# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COX1 PF00115.20 KDO15665.1 - 1.1e-152 508.9 58.8 1.4e-152 508.5 58.8 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Oxidored_q3 PF00499.20 KDO15666.1 - 7.6e-34 116.5 18.9 1.2e-33 115.8 18.9 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PepSY_TM PF03929.16 KDO15666.1 - 0.31 10.7 0.0 0.31 10.7 0.0 2.1 2 1 0 2 2 2 0 PepSY-associated TM region UPF0242 PF06785.11 KDO15666.1 - 8 6.5 8.3 36 4.4 4.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATP-synt_C PF00137.21 KDO15667.1 - 6.5e-12 45.6 11.7 7.9e-12 45.4 11.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.13 KDO15667.1 - 0.097 11.0 4.4 0.1 11.0 4.4 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Complex1_30kDa PF00329.19 KDO15668.1 - 4.5e-41 140.3 0.0 5.6e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Cytochrome_B PF00033.19 KDO15669.1 - 1.6e-80 269.4 17.4 1.6e-80 269.4 17.4 2.1 3 1 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 KDO15669.1 - 1.8e-43 148.5 12.8 1.8e-43 148.5 12.8 2.0 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 KDO15669.1 - 1.6e-36 124.7 5.5 1.6e-36 124.7 5.5 3.0 3 1 1 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Oxidored_q4 PF00507.19 KDO15670.1 - 1.1e-29 102.5 6.6 1.1e-29 102.5 6.6 1.6 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Ninjurin PF04923.12 KDO15670.1 - 0.1 12.5 2.3 0.14 12.1 2.1 1.5 1 1 0 1 1 1 0 Ninjurin DUF4212 PF13937.6 KDO15670.1 - 0.15 12.4 11.6 5.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF3169 PF11368.8 KDO15670.1 - 0.22 11.0 0.2 0.22 11.0 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) EVC2_like PF12297.8 KDO15670.1 - 0.28 9.8 0.0 0.28 9.8 0.0 1.4 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein TssO PF17561.2 KDO15670.1 - 0.55 10.3 3.3 0.79 9.8 3.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO DHHC PF01529.20 KDO15670.1 - 0.84 9.7 9.3 2 8.6 9.3 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Molybdopterin PF00384.22 KDO15671.1 - 6.3e-47 160.5 0.1 5.3e-33 114.6 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 KDO15671.1 - 5.4e-14 51.5 0.1 5.4e-14 51.5 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 KDO15671.1 - 1.9e-12 47.1 0.0 3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 KDO15671.1 - 4.6e-06 26.5 0.2 9.5e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KDO15671.1 - 0.13 12.1 1.4 4 7.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain NADHdh PF00146.21 KDO15672.1 - 5.4e-125 416.6 19.0 6.2e-125 416.4 19.0 1.0 1 0 0 1 1 1 1 NADH dehydrogenase TCR_zetazeta PF11628.8 KDO15672.1 - 3.1 7.6 6.6 13 5.5 0.7 2.9 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Oxidored_q2 PF00420.24 KDO15673.1 - 7.9e-18 64.0 13.4 1e-17 63.7 13.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Proton_antipo_M PF00361.20 KDO15674.1 - 1.1e-83 280.9 23.1 1.1e-83 280.9 23.1 2.7 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 KDO15674.1 - 1.3e-19 70.1 6.5 1.3e-19 70.1 6.5 4.1 3 1 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 KDO15674.1 - 9.7e-17 61.1 17.4 9.7e-17 61.1 17.4 5.2 3 2 1 4 4 4 2 NADH dehydrogenase subunit 5 C-terminus HTH_17 PF12728.7 KDO15674.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Proton_antipo_M PF00361.20 KDO15675.1 - 5.2e-67 226.1 33.9 5.2e-67 226.1 33.9 2.2 2 0 0 2 2 2 1 Proton-conducting membrane transporter Ribosomal_S10 PF00338.22 KDO15676.1 - 1.3e-13 51.0 2.6 1.5e-13 50.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Phos_pyr_kin PF08543.12 KDO15676.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Ribosomal_S7 PF00177.21 KDO15677.1 - 2e-15 56.7 0.7 3.4e-15 56.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4508 PF14969.6 KDO15677.1 - 0.007 16.6 2.1 0.51 10.6 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) ATP-synt_ab PF00006.25 KDO15678.1 - 8.6e-71 238.0 0.0 1.4e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KDO15678.1 - 1.1e-46 158.3 3.1 1.9e-46 157.5 3.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KDO15678.1 - 6.2e-13 49.1 0.7 1.5e-12 47.8 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 KDO15678.1 - 0.00018 21.6 0.3 0.0045 17.1 0.3 2.6 1 1 0 1 1 1 1 HAS barrel domain Ribosomal_L5_C PF00673.21 KDO15679.1 - 2.6e-12 46.7 0.8 4e-12 46.2 0.3 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KDO15679.1 - 4.3e-06 27.0 5.6 4.3e-06 27.0 5.6 2.1 2 1 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L14 PF00238.19 KDO15680.1 - 2e-32 111.8 3.4 2.3e-32 111.6 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RsgI_N PF12791.7 KDO15680.1 - 0.045 13.7 0.8 0.045 13.7 0.8 2.9 3 1 1 4 4 4 0 Anti-sigma factor N-terminus Myco_arth_vir_N PF09610.10 KDO15680.1 - 2.8 8.1 10.2 6.8 6.9 0.1 2.7 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) TatC PF00902.18 KDO15681.1 - 3.6e-21 75.9 39.8 4.5e-21 75.6 39.8 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Ribosomal_S11 PF00411.19 KDO15682.1 - 2.1e-15 57.0 0.0 2.8e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S13 PF00416.22 KDO15683.1 - 5.3e-20 72.1 3.8 5.1e-18 65.7 3.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Med26 PF08711.11 KDO15683.1 - 0.17 11.9 3.6 0.11 12.5 0.9 2.0 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Ribosomal_L2_C PF03947.18 KDO15684.1 - 7.4e-53 178.1 0.4 1.4e-52 177.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KDO15684.1 - 1.9e-25 88.6 2.5 3.2e-25 87.9 1.3 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Terminase_1 PF03354.15 KDO15684.1 - 0.066 11.7 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase Ribosomal_S3_C PF00189.20 KDO15685.1 - 3e-13 50.1 0.1 6.2e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Ribosomal_L16 PF00252.18 KDO15686.1 - 3.1e-42 143.7 1.5 3.4e-42 143.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Biotin_lipoyl_2 PF13533.6 KDO15686.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like DLP_helical PF18709.1 KDO15686.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain YMF19 PF02326.15 KDO15687.1 - 5.8e-08 33.4 16.4 5.8e-08 33.4 16.4 2.0 1 1 1 2 2 2 1 Plant ATP synthase F0 ATP-synt_B PF00430.18 KDO15687.1 - 0.06 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ribosomal_S14 PF00253.21 KDO15688.1 - 3.4e-19 68.3 0.2 5.2e-19 67.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S8 PF00410.19 KDO15689.1 - 5.8e-31 107.1 7.0 6.5e-31 106.9 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 DUF2513 PF10711.9 KDO15689.1 - 0.0038 17.5 0.3 0.0061 16.8 0.3 1.4 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) Endonuc_subdom PF09062.10 KDO15689.1 - 0.029 15.2 4.9 0.055 14.3 4.9 1.4 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain pXO2-72 PF17443.2 KDO15689.1 - 2.3 8.5 7.4 0.23 11.8 2.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein pXO2-72 Ribosomal_L6 PF00347.23 KDO15690.1 - 7e-14 52.3 0.0 1.2e-07 32.3 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S2 PF00318.20 KDO15691.1 - 4.2e-24 85.0 6.9 6.7e-14 51.6 1.8 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S4 PF00163.19 KDO15692.1 - 0.0019 19.1 5.5 0.0038 18.1 5.5 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF3288 PF11691.8 KDO15692.1 - 0.11 12.5 1.3 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) Complex1_49kDa PF00346.19 KDO15693.1 - 1.5e-122 407.9 0.0 2e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KDO15693.1 - 0.0007 18.6 0.0 0.0016 17.5 0.0 1.6 2 0 0 2 2 2 1 Nickel-dependent hydrogenase Proton_antipo_M PF00361.20 KDO15694.1 - 1.4e-76 257.5 31.6 1.4e-76 257.5 31.6 2.8 3 1 0 3 3 3 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 KDO15694.1 - 7.6e-05 22.8 21.0 7.6e-05 22.8 21.0 5.6 4 2 1 5 5 5 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF3377 PF11857.8 KDO15694.1 - 0.028 14.3 0.7 0.028 14.3 0.7 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) COX3 PF00510.18 KDO15695.1 - 1.6e-113 378.8 33.0 1.8e-113 378.6 33.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III ATP-synt_A PF00119.20 KDO15696.1 - 6.8e-48 163.4 38.2 8.3e-48 163.1 38.2 1.0 1 0 0 1 1 1 1 ATP synthase A chain COX2 PF00116.20 KDO15697.1 - 8.8e-62 206.3 1.1 9.1e-62 206.3 0.1 1.5 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 KDO15697.1 - 1.2e-29 102.3 4.4 2.4e-29 101.3 4.4 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF2244 PF10003.9 KDO15698.1 - 0.031 14.0 0.2 0.031 14.0 0.2 1.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) 2TM PF13239.6 KDO15698.1 - 0.055 13.8 0.2 0.088 13.1 0.2 1.4 1 0 0 1 1 1 0 2TM domain Transglut_core PF01841.19 KDO15698.1 - 0.3 11.5 1.9 1.6 9.2 1.9 2.0 1 1 0 1 1 1 0 Transglutaminase-like superfamily SecY PF00344.20 KDO15700.1 - 2.3e-65 220.9 13.4 2.6e-65 220.7 13.4 1.0 1 0 0 1 1 1 1 SecY translocase YlaH PF14036.6 KDO15700.1 - 2.9 8.3 6.9 5.3 7.4 0.2 3.2 3 0 0 3 3 3 0 YlaH-like protein p450 PF00067.22 KDO15701.1 - 1.1e-07 31.0 0.0 1.3e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4 PF00097.25 KDO15702.1 - 4.5e-06 26.4 13.5 6.3e-06 26.0 13.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO15702.1 - 8.2e-06 25.6 12.2 1.2e-05 25.0 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KDO15702.1 - 8.8e-06 25.8 6.3 1.1e-05 25.5 6.3 1.2 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KDO15702.1 - 9.6e-06 25.4 4.9 1.3e-05 25.0 4.9 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KDO15702.1 - 0.00012 22.1 10.6 0.0002 21.5 10.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO15702.1 - 0.00016 21.6 10.4 0.00025 21.0 10.4 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO15702.1 - 0.00047 20.0 12.0 0.0006 19.6 12.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO15702.1 - 0.014 15.7 12.2 0.022 15.1 12.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KDO15702.1 - 0.056 13.4 12.9 0.12 12.4 13.0 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO15702.1 - 0.66 9.9 11.0 0.95 9.4 11.0 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MYND PF01753.18 KDO15702.1 - 3.2 7.9 9.5 1.4 9.1 1.1 2.2 2 0 0 2 2 2 0 MYND finger Pro-kuma_activ PF09286.11 KDO15703.1 - 6.1e-14 52.5 0.0 1.1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DEC-1_N PF04625.13 KDO15703.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Voltage_CLC PF00654.20 KDO15704.1 - 3.4e-43 148.3 9.4 3.4e-43 148.3 9.4 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel Haem_degrading PF03928.14 KDO15704.1 - 0.021 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Haem-degrading LRR_8 PF13855.6 KDO15705.1 - 9.9e-17 60.5 19.3 5.1e-09 35.8 1.8 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KDO15705.1 - 9.3e-13 48.2 12.0 0.0005 20.4 0.1 3.9 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO15705.1 - 8.9e-09 34.7 10.2 0.56 10.4 0.0 5.6 5 0 0 5 5 5 5 Leucine Rich repeat LRR_9 PF14580.6 KDO15705.1 - 3.2e-08 33.3 2.1 5.2e-08 32.6 2.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KDO15705.1 - 0.0012 19.0 8.5 32 5.6 0.1 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat Methyltransf_13 PF08421.11 KDO15706.1 - 0.055 13.7 0.1 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative zinc binding domain SNAP PF14938.6 KDO15708.1 - 1.4e-10 41.1 3.0 1.5e-10 41.0 3.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 KDO15708.1 - 0.028 14.2 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat NSF PF02071.20 KDO15708.1 - 0.042 14.5 1.2 2.1 9.4 0.0 3.1 2 1 1 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat PhageMin_Tail PF10145.9 KDO15708.1 - 0.061 13.2 0.2 0.064 13.1 0.2 1.0 1 0 0 1 1 1 0 Phage-related minor tail protein TPR_2 PF07719.17 KDO15708.1 - 0.089 12.9 0.6 0.39 11.0 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO15708.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 KDO15710.1 - 3.8e-07 31.1 0.0 8.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO15710.1 - 0.00031 20.6 0.2 0.00049 20.0 0.2 1.3 1 0 0 1 1 1 1 Trypsin Cpn60_TCP1 PF00118.24 KDO15712.1 - 0.056 12.1 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Ank_4 PF13637.6 KDO15714.1 - 0.043 14.4 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Use1 PF09753.9 KDO15715.1 - 2.4e-07 30.8 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Zip PF02535.22 KDO15716.1 - 1.7e-11 43.9 12.9 4.7e-10 39.2 5.0 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1453 PF07301.11 KDO15716.1 - 0.046 13.7 2.8 0.049 13.6 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1453) Tmemb_14 PF03647.13 KDO15716.1 - 0.41 11.4 0.1 0.41 11.4 0.1 3.1 3 1 0 3 3 3 0 Transmembrane proteins 14C Acyl_transf_3 PF01757.22 KDO15716.1 - 4.8 6.2 15.3 0.14 11.2 4.5 2.8 2 1 0 3 3 3 0 Acyltransferase family NACHT PF05729.12 KDO15719.1 - 4.7e-08 33.1 0.1 6.2e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KDO15719.1 - 0.00088 19.7 0.0 0.0016 18.8 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO15719.1 - 0.0022 18.4 0.4 0.0044 17.4 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO15719.1 - 0.0048 17.2 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KDO15719.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO15719.1 - 0.046 12.9 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 KDO15719.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KDO15719.1 - 0.11 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO15719.1 - 0.2 12.1 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Aa_trans PF01490.18 KDO15720.1 - 5.9e-10 38.4 0.7 6.1e-10 38.4 0.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM238 PF15125.6 KDO15720.1 - 0.018 15.2 1.5 0.023 14.9 1.5 1.1 1 0 0 1 1 1 0 TMEM238 protein family Aa_trans PF01490.18 KDO15721.1 - 1.6e-23 83.1 10.9 1.9e-23 82.8 10.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2157 PF09925.9 KDO15721.1 - 6.5 6.5 9.4 1.6 8.5 0.6 3.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Flavin_Reduct PF01613.18 KDO15722.1 - 6.9e-19 68.4 0.3 9.4e-19 68.0 0.3 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KDO15722.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ERbeta_N PF12497.8 KDO15723.1 - 0.12 12.2 0.7 0.13 12.1 0.7 1.0 1 0 0 1 1 1 0 Estrogen receptor beta CN_hydrolase PF00795.22 KDO15726.1 - 2.5e-12 46.7 0.0 2.7e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CDK2AP PF09806.9 KDO15728.1 - 0.16 12.0 5.5 0.25 11.4 5.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein EF-hand_8 PF13833.6 KDO15730.1 - 5.3e-20 71.0 2.4 9.5e-12 44.6 0.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KDO15730.1 - 1.6e-19 70.1 0.4 6.6e-13 48.9 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO15730.1 - 8.5e-18 62.5 7.2 2.6e-07 29.7 1.5 3.6 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO15730.1 - 3.4e-12 45.3 1.3 0.00015 21.4 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 KDO15730.1 - 3.2e-11 43.4 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO15730.1 - 4.2e-05 22.9 5.3 0.031 13.8 1.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 KDO15730.1 - 0.001 19.0 0.5 0.011 15.7 0.3 2.1 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand UPF0029 PF01205.19 KDO15731.1 - 8.5e-17 61.4 0.1 1.2e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RT_RNaseH_2 PF17919.1 KDO15732.1 - 0.096 12.7 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF2767 PF10965.8 KDO15732.1 - 0.14 12.1 3.8 0.19 11.7 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2767) Ephrin_rec_like PF07699.13 KDO15734.1 - 5.2e-06 26.1 80.5 0.00065 19.4 9.7 9.4 2 2 8 10 10 10 9 Putative ephrin-receptor like NCD3G PF07562.14 KDO15734.1 - 0.00094 19.1 5.6 0.00094 19.1 5.6 8.5 2 2 5 9 9 9 6 Nine Cysteines Domain of family 3 GPCR Cnn_1N PF07989.11 KDO15735.1 - 0.00083 19.5 2.5 0.0015 18.7 2.5 1.4 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 TCR PF03638.15 KDO15737.1 - 0.0098 16.2 17.7 0.0098 16.2 17.7 4.3 2 1 2 4 4 4 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Frag1 PF10277.9 KDO15738.1 - 6.7e-13 48.7 20.6 8.2e-13 48.4 20.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SdpI PF13630.6 KDO15738.1 - 7.2 6.8 12.9 0.083 13.0 3.0 2.6 3 1 0 3 3 3 0 SdpI/YhfL protein family Med26 PF08711.11 KDO15739.1 - 3.6e-08 33.3 0.3 1.2e-07 31.7 0.2 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RTP1_C1 PF10363.9 KDO15739.1 - 0.022 14.9 0.3 0.038 14.2 0.3 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 BID PF06393.11 KDO15739.1 - 0.06 12.9 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) ArnB_C PF18677.1 KDO15739.1 - 0.2 11.8 1.6 0.17 12.0 0.5 1.4 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain adh_short PF00106.25 KDO15741.1 - 1.3e-18 67.2 0.4 1.4e-18 67.0 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO15741.1 - 1.4e-10 41.1 0.2 1.5e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO15741.1 - 4.7e-07 29.9 0.4 5.6e-07 29.6 0.4 1.0 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KDO15741.1 - 0.071 13.0 0.3 0.078 12.9 0.3 1.3 1 1 0 1 1 1 0 YjeF-related protein N-terminus zf_CopZ PF18423.1 KDO15743.1 - 0.073 13.0 0.5 0.18 11.8 0.5 1.6 1 0 0 1 1 1 0 Zinc binding domain Lectin_N PF03954.14 KDO15744.1 - 0.098 12.4 2.3 0.19 11.5 2.3 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4231 PF14015.6 KDO15744.1 - 6.4 7.3 8.1 13 6.3 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) VIT1 PF01988.19 KDO15745.1 - 1.6e-09 38.0 3.4 2.4e-09 37.4 3.4 1.3 1 1 0 1 1 1 1 VIT family Frag1 PF10277.9 KDO15747.1 - 0.013 15.1 0.8 0.015 14.9 0.8 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF3228 PF11539.8 KDO15748.1 - 1e-31 110.0 0.0 1.7e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) SWIM PF04434.17 KDO15748.1 - 5.8e-06 25.9 1.7 1.2e-05 24.9 0.2 2.2 2 0 0 2 2 2 1 SWIM zinc finger zf-CCHC_2 PF13696.6 KDO15748.1 - 0.038 13.8 0.4 0.088 12.7 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle PALP PF00291.25 KDO15749.1 - 2.5e-45 155.1 0.0 3.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 KDO15749.1 - 0.009 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DFP PF04127.15 KDO15749.1 - 0.16 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF4265 PF14085.6 KDO15750.1 - 0.00025 21.0 1.8 0.00081 19.4 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4265) CtIP_N PF10482.9 KDO15750.1 - 0.00038 20.5 8.4 0.00038 20.5 8.4 2.8 2 1 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain IFT57 PF10498.9 KDO15750.1 - 0.00093 18.3 13.9 0.00093 18.3 13.9 1.9 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 KDO15750.1 - 0.0033 16.3 33.4 0.55 9.1 0.6 3.1 1 1 2 3 3 3 3 Spc7 kinetochore protein FlxA PF14282.6 KDO15750.1 - 0.011 15.7 16.6 0.13 12.3 3.5 4.3 1 1 3 4 4 4 0 FlxA-like protein DUF2465 PF10239.9 KDO15750.1 - 0.021 14.1 12.4 0.29 10.3 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2465) YabA PF06156.13 KDO15750.1 - 0.022 15.4 22.9 12 6.6 0.6 5.2 2 1 2 4 4 4 0 Initiation control protein YabA APG6_N PF17675.1 KDO15750.1 - 0.023 15.3 38.2 1.8 9.1 10.9 4.2 1 1 2 3 3 3 0 Apg6 coiled-coil region KASH_CCD PF14662.6 KDO15750.1 - 0.032 14.1 30.8 0.51 10.1 14.5 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 KDO15750.1 - 0.051 12.9 26.9 1.2 8.5 12.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HOOK PF05622.12 KDO15750.1 - 0.067 11.3 29.8 0.15 10.2 29.8 1.6 1 1 0 1 1 1 0 HOOK protein TolA_bind_tri PF16331.5 KDO15750.1 - 0.1 12.7 24.7 0.17 11.9 6.4 4.4 3 1 1 4 4 4 0 TolA binding protein trimerisation ATG16 PF08614.11 KDO15750.1 - 0.11 12.8 43.3 1 9.5 21.0 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fungal_TACC PF12709.7 KDO15750.1 - 0.13 12.8 0.3 0.13 12.8 0.3 4.7 4 2 1 5 5 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 KDO15750.1 - 0.18 11.6 24.2 3.2 7.6 0.1 5.8 2 1 5 7 7 7 0 Septum formation initiator Fez1 PF06818.15 KDO15750.1 - 0.24 11.8 31.0 0.41 11.1 17.0 2.5 1 1 1 2 2 2 0 Fez1 Seryl_tRNA_N PF02403.22 KDO15750.1 - 0.32 11.2 25.0 3.3 8.0 3.8 4.9 1 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 KDO15750.1 - 0.42 11.0 26.5 2.2 8.7 7.8 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) CENP-H PF05837.12 KDO15750.1 - 0.48 10.8 31.7 0.7 10.3 8.4 4.6 2 1 2 4 4 4 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 KDO15750.1 - 0.71 9.9 33.1 1.5 8.8 11.0 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 KDO15750.1 - 0.87 10.0 8.4 0.89 9.9 0.2 4.0 2 2 1 3 3 3 0 TSC-22/dip/bun family LCD1 PF09798.9 KDO15750.1 - 0.93 7.9 18.4 0.17 10.3 5.4 2.2 1 1 1 2 2 2 0 DNA damage checkpoint protein Cauli_DNA-bind PF03310.13 KDO15750.1 - 1.4 9.0 4.8 1.5 8.9 0.4 2.7 1 1 0 2 2 2 0 Caulimovirus DNA-binding protein DUF1664 PF07889.12 KDO15750.1 - 1.6 8.8 18.1 2.5 8.2 2.9 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) YwqJ-deaminase PF14431.6 KDO15750.1 - 1.6 8.9 6.9 0.74 10.0 3.3 2.3 1 1 1 2 2 2 0 YwqJ-like deaminase HALZ PF02183.18 KDO15750.1 - 1.8 8.8 18.8 4.3 7.6 0.1 6.3 6 1 1 7 7 7 0 Homeobox associated leucine zipper UPF0242 PF06785.11 KDO15750.1 - 1.9 8.5 25.8 0.38 10.8 13.0 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KDO15750.1 - 2.1 8.4 22.6 2.7 8.0 0.5 4.9 3 3 2 5 5 5 0 Prefoldin subunit DUF4795 PF16043.5 KDO15750.1 - 4.3 6.9 22.5 36 3.9 22.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KLRAQ PF10205.9 KDO15750.1 - 4.6 7.5 17.9 2.4 8.5 3.5 3.8 1 1 3 4 4 4 0 Predicted coiled-coil domain-containing protein DUF1192 PF06698.11 KDO15750.1 - 7.4 6.7 16.8 9.7 6.3 1.6 4.9 4 2 1 5 5 5 0 Protein of unknown function (DUF1192) FapA PF03961.13 KDO15750.1 - 8.7 4.8 15.5 4.1 5.9 4.8 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF948 PF06103.11 KDO15750.1 - 9.1 6.6 20.1 11 6.4 3.5 4.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 KDO15750.1 - 9.7 5.9 37.4 8.4e+02 -0.4 37.4 2.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RSN1_TM PF13967.6 KDO15751.1 - 3e-27 95.3 0.0 3.5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport LRR_6 PF13516.6 KDO15754.1 - 0.12 12.4 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat AA_permease_2 PF13520.6 KDO15756.1 - 7.2e-08 31.7 25.3 8.4e-08 31.5 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO15756.1 - 1e-07 30.9 21.1 2e-07 30.0 21.1 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO15757.1 - 2.6e-07 29.8 13.8 4e-07 29.2 11.6 2.0 1 1 1 2 2 2 1 Amino acid permease CbtB PF09489.10 KDO15757.1 - 0.016 15.3 8.0 2.1 8.5 0.0 3.5 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtB) LRR_8 PF13855.6 KDO15758.1 - 9.7e-09 34.9 1.9 2e-08 33.9 1.9 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KDO15758.1 - 8.7e-08 32.4 1.6 1.1e-06 28.9 0.3 2.8 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO15758.1 - 2.8e-06 27.7 12.0 5.5e-06 26.7 12.0 1.5 1 0 0 1 1 1 1 LNR domain PX PF00787.24 KDO15759.1 - 1.1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PX domain HpcH_HpaI PF03328.14 KDO15763.1 - 1.6e-14 53.6 0.0 1.8e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PP2C PF00481.21 KDO15764.1 - 2.2e-23 83.2 0.0 2.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C EMP70 PF02990.16 KDO15767.1 - 5.1e-132 441.2 23.8 5.1e-132 441.2 23.8 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 AbrB_C PF18277.1 KDO15768.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AbrB C-terminal domain AAA PF00004.29 KDO15769.1 - 1.6e-35 122.4 0.0 3.5e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO15769.1 - 2.1e-08 34.0 0.0 5.9e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO15769.1 - 9.8e-07 28.9 0.2 4.8e-06 26.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO15769.1 - 7e-06 26.4 0.2 0.015 15.5 0.0 3.1 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 KDO15769.1 - 0.00085 19.7 0.1 0.0061 17.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KDO15769.1 - 0.0037 17.4 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KDO15769.1 - 0.021 14.6 0.1 0.47 10.1 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 KDO15769.1 - 0.022 15.0 0.0 0.076 13.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO15769.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KDO15769.1 - 0.04 13.8 0.1 11 5.9 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_14 PF13173.6 KDO15769.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KDO15769.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 KDO15769.1 - 0.067 13.3 0.0 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 KDO15769.1 - 0.085 12.6 0.1 0.56 9.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO15769.1 - 0.089 13.3 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 KDO15769.1 - 0.096 12.5 0.1 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA+ lid domain AAA_11 PF13086.6 KDO15769.1 - 0.098 12.4 0.1 0.21 11.3 0.0 1.6 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 KDO15769.1 - 0.1 11.9 0.1 2.4 7.4 0.0 2.0 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 KDO15769.1 - 0.14 11.6 0.1 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KDO15769.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Talin_middle PF09141.10 KDO15769.1 - 0.47 10.5 2.7 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Talin, middle domain Cation_efflux PF01545.21 KDO15770.1 - 0.0047 16.7 1.2 0.0052 16.5 1.2 1.1 1 0 0 1 1 1 1 Cation efflux family EGF_2 PF07974.13 KDO15771.1 - 2.4e-05 24.6 1.5 2.4e-05 24.6 1.5 2.2 3 0 0 3 3 3 1 EGF-like domain hEGF PF12661.7 KDO15771.1 - 0.15 12.7 5.4 0.76 10.5 5.4 2.3 1 0 0 1 1 1 0 Human growth factor-like EGF CwsA PF10814.8 KDO15772.1 - 0.0013 18.9 0.3 0.0022 18.1 0.3 1.3 1 0 0 1 1 1 1 Cell wall synthesis protein CwsA Transcrip_reg PF01709.20 KDO15773.1 - 1.5e-72 243.9 0.2 1.8e-72 243.7 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator Glyoxalase_3 PF13468.6 KDO15773.1 - 0.0093 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Tetraspanin PF00335.20 KDO15774.1 - 3.1e-17 63.1 7.2 3.8e-17 62.8 7.2 1.2 1 0 0 1 1 1 1 Tetraspanin family SCAMP PF04144.13 KDO15774.1 - 0.0022 18.3 4.5 0.0034 17.7 4.5 1.5 1 0 0 1 1 1 1 SCAMP family DUF373 PF04123.13 KDO15774.1 - 0.0031 17.0 3.4 0.004 16.6 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Tweety PF04906.13 KDO15774.1 - 0.017 13.8 1.0 0.029 13.0 1.0 1.3 1 0 0 1 1 1 0 Tweety COX1 PF00115.20 KDO15774.1 - 0.032 13.1 7.5 0.039 12.8 7.5 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Abhydrolase_9_N PF15420.6 KDO15774.1 - 0.1 12.6 1.7 0.17 11.9 1.7 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF3043 PF11241.8 KDO15774.1 - 0.18 11.8 0.6 0.32 11.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PPR_1 PF12854.7 KDO15774.1 - 0.34 10.7 2.5 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 PPR repeat DUF2981 PF11200.8 KDO15774.1 - 0.37 10.5 6.6 0.55 9.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF3098 PF11297.8 KDO15774.1 - 0.42 10.2 10.4 5.6 6.6 6.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Claudin_3 PF06653.11 KDO15774.1 - 0.45 10.4 9.0 0.97 9.4 9.0 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like OAD_gamma PF04277.13 KDO15774.1 - 0.84 10.3 4.9 16 6.2 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF2749 PF10907.8 KDO15774.1 - 1.8 8.8 5.6 1 9.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Phage_holin_3_6 PF07332.11 KDO15774.1 - 2.3 8.3 18.7 0.31 11.1 8.7 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Sulfotransfer_1 PF00685.27 KDO15776.1 - 1.5e-07 31.1 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KDO15776.1 - 0.028 14.8 0.0 0.94 9.8 0.0 2.3 1 1 0 2 2 2 0 Sulfotransferase family Sulfotransfer_2 PF03567.14 KDO15776.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Pkinase PF00069.25 KDO15777.1 - 7.3e-47 159.9 0.0 1e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO15777.1 - 2.2e-45 155.0 0.0 2.9e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO15777.1 - 0.0013 18.7 0.0 0.0067 16.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO15777.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pex2_Pex12 PF04757.14 KDO15777.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region LapA_dom PF06305.11 KDO15777.1 - 0.13 12.1 0.4 0.37 10.6 0.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PX PF00787.24 KDO15780.1 - 5.8e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 PX domain Sugar_tr PF00083.24 KDO15783.1 - 6.8e-27 94.4 9.3 7.9e-27 94.2 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO15783.1 - 2.4e-19 69.5 17.7 3.3e-19 69.0 17.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KDO15783.1 - 7.6e-05 22.2 4.4 9.5e-05 21.8 4.4 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 KDO15783.1 - 0.00033 19.7 1.9 0.00046 19.2 1.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KDO15783.1 - 0.00076 18.0 1.3 0.00087 17.8 1.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KDO15783.1 - 0.0065 15.1 4.6 0.0084 14.7 4.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TetR_C_14 PF17754.1 KDO15784.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 MftR C-terminal domain DUF4035 PF13227.6 KDO15787.1 - 0.064 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) ATP1G1_PLM_MAT8 PF02038.16 KDO15788.1 - 0.093 12.2 0.4 0.23 10.9 0.1 1.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Homoserine_dh PF00742.19 KDO15792.1 - 3.1e-22 79.3 0.0 3.4e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Homoserine dehydrogenase THF_DHG_CYH_C PF02882.19 KDO15794.1 - 0.011 15.0 0.6 0.14 11.5 0.6 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1577 PF07614.11 KDO15794.1 - 0.075 12.1 0.0 0.092 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Macro PF01661.21 KDO15795.1 - 2.2e-06 27.7 0.1 0.00011 22.2 0.1 2.4 1 1 0 1 1 1 1 Macro domain DUF368 PF04018.13 KDO15795.1 - 0.075 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Remorin_C PF03763.13 KDO15796.1 - 0.051 13.4 1.5 0.069 13.0 1.5 1.3 1 1 0 1 1 1 0 Remorin, C-terminal region DUF3138 PF11336.8 KDO15796.1 - 0.7 8.4 4.4 0.74 8.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DAGK_cat PF00781.24 KDO15798.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ras PF00071.22 KDO15799.1 - 2e-33 115.3 0.0 3.2e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO15799.1 - 9.5e-26 90.4 0.0 1.6e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO15799.1 - 6.4e-15 55.0 0.0 9.2e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO15799.1 - 5.7e-06 25.9 0.0 8.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO15799.1 - 3e-05 24.1 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO15799.1 - 0.00014 21.4 0.7 0.0032 17.0 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KDO15799.1 - 0.00045 20.0 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KDO15799.1 - 0.00068 19.1 0.5 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO15799.1 - 0.0076 15.5 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 KDO15799.1 - 0.05 13.4 0.5 6 6.6 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KDO15799.1 - 0.067 13.6 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF1980 PF09323.10 KDO15799.1 - 0.5 10.2 1.8 0.69 9.8 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) YL1 PF05764.13 KDO15799.1 - 1.1 9.4 7.0 0.19 11.8 2.6 1.8 2 0 0 2 2 2 0 YL1 nuclear protein ABC2_membrane PF01061.24 KDO15801.1 - 1.1e-27 96.9 30.3 6.1e-21 74.8 16.9 3.0 2 1 1 3 3 3 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 KDO15801.1 - 0.19 11.0 21.0 0.69 9.1 21.0 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 KDO15801.1 - 4.8 6.2 31.8 0.037 13.1 19.6 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Mg_trans_NIPA PF05653.14 KDO15802.1 - 1.6e-09 37.3 2.7 2.3e-09 36.8 2.7 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA Adaptin_N PF01602.20 KDO15803.1 - 0.067 11.7 0.0 0.11 11.1 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region Ku_C PF03730.14 KDO15806.1 - 0.73 10.6 5.4 1.6 9.4 5.4 1.6 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm LRR_4 PF12799.7 KDO15808.1 - 0.0033 17.8 0.3 0.29 11.6 0.1 3.1 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO15808.1 - 0.075 13.1 3.6 15 5.9 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Calpain_III PF01067.22 KDO15809.1 - 7.8e-21 74.8 0.4 2.2e-05 24.7 0.0 4.1 2 2 0 3 3 3 3 Calpain large subunit, domain III PDZ_2 PF13180.6 KDO15812.1 - 0.0012 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO15812.1 - 0.014 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KDO15812.1 - 0.014 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DUF3584 PF12128.8 KDO15812.1 - 0.11 10.1 12.1 0.13 9.7 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM76 PF16046.5 KDO15812.1 - 0.98 8.7 7.2 0.69 9.2 5.6 1.5 1 1 0 1 1 1 0 FAM76 protein Ank_5 PF13857.6 KDO15813.1 - 2.1e-12 47.0 2.5 0.035 14.4 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO15813.1 - 3.8e-11 43.4 0.9 1.2e-05 25.8 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO15813.1 - 1e-05 26.0 3.7 0.061 13.9 0.1 3.6 2 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO15813.1 - 0.00077 19.7 0.1 16 6.5 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 KDO15814.1 - 6.5e-54 180.5 16.6 2.2e-14 53.8 0.1 5.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO15814.1 - 1.9e-45 152.6 17.8 9.6e-12 45.2 0.1 5.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO15814.1 - 1.4e-39 129.6 8.1 0.001 19.3 0.0 8.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KDO15814.1 - 2.7e-38 129.5 16.6 1.1e-08 35.2 1.2 6.9 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO15814.1 - 4.4e-37 124.9 19.8 3e-06 27.4 0.4 8.3 9 0 0 9 9 9 8 Ankyrin repeat PH PF00169.29 KDO15816.1 - 1.7e-15 57.4 0.1 3.5e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 PH domain RA PF00788.23 KDO15816.1 - 9.3e-07 29.4 0.6 2.2e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 KDO15816.1 - 1.2e-05 25.7 0.1 0.00023 21.5 0.1 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KDO15816.1 - 0.0034 17.6 0.2 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain USP7_C2 PF14533.6 KDO15816.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal RGS PF00615.19 KDO15816.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Regulator of G protein signaling domain Ran_BP1 PF00638.18 KDO15817.1 - 8e-09 35.8 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KDO15817.1 - 0.39 11.6 54.4 2.7e+02 2.5 19.2 3.3 1 1 1 2 2 2 0 Nucleoporin FG repeat region bZIP_2 PF07716.15 KDO15818.1 - 0.0028 17.7 5.6 0.0028 17.7 5.6 2.1 2 0 0 2 2 2 1 Basic region leucine zipper T7SS_ESX_EspC PF10824.8 KDO15818.1 - 0.079 13.4 0.1 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm CALM_bind PF16025.5 KDO15818.1 - 2.2 8.8 9.0 9.6 6.8 9.0 2.3 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding Dynein_heavy PF03028.15 KDO15820.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain FAD_oxidored PF12831.7 KDO15821.1 - 6.2e-07 29.1 0.0 7.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO15821.1 - 7.5e-07 28.6 0.1 1.3e-06 27.8 0.1 1.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KDO15821.1 - 1.9e-06 26.9 0.1 2.3e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KDO15821.1 - 5.3e-06 25.9 0.1 7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO15821.1 - 9.2e-05 22.6 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KDO15821.1 - 0.00034 19.9 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KDO15821.1 - 0.001 18.3 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KDO15821.1 - 0.0016 19.0 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO15821.1 - 0.0033 16.7 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO15821.1 - 0.0046 16.6 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KDO15821.1 - 0.032 13.5 0.0 0.07 12.4 0.0 1.5 1 1 1 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KDO15821.1 - 0.074 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KDO15821.1 - 0.13 12.1 0.1 0.3 11.0 0.0 1.5 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArsA_ATPase PF02374.15 KDO15821.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase INTS2 PF14750.6 KDO15825.1 - 0.0046 14.6 0.0 0.0046 14.6 0.0 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 ELFV_dehydrog PF00208.21 KDO15826.1 - 8.1e-57 192.7 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KDO15826.1 - 1.2e-09 36.4 0.0 2.4e-07 28.8 0.0 2.3 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase fn3 PF00041.21 KDO15827.1 - 3.1e-06 27.4 1.7 7.4e-06 26.2 1.7 1.6 1 0 0 1 1 1 1 Fibronectin type III domain TIG PF01833.24 KDO15827.1 - 0.0014 18.7 3.2 0.011 15.8 0.0 3.2 3 0 0 3 3 3 1 IPT/TIG domain DUF3787 PF12655.7 KDO15827.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) RRM_1 PF00076.22 KDO15828.1 - 0.00028 20.6 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HalX PF08663.10 KDO15828.1 - 0.0043 17.3 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 HalX domain zf-DBF PF07535.12 KDO15830.1 - 0.12 12.5 7.8 0.36 11.0 0.1 3.2 4 0 0 4 4 4 0 DBF zinc finger Atx10homo_assoc PF09759.9 KDO15831.1 - 7.1e-31 106.2 0.1 1.3e-30 105.3 0.1 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KDO15831.1 - 0.036 14.1 0.2 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KDO15831.1 - 0.22 11.9 1.5 0.6 10.5 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat Peptidase_S46 PF10459.9 KDO15833.1 - 0.0027 16.4 0.2 0.0027 16.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase S46 Trypsin_2 PF13365.6 KDO15833.1 - 0.0096 16.8 0.1 0.013 16.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO15833.1 - 0.024 14.5 0.4 0.027 14.3 0.4 1.1 1 0 0 1 1 1 0 Trypsin Peptidase_S39 PF02122.15 KDO15833.1 - 0.044 13.3 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase S39 Peptidase_C4 PF00863.19 KDO15833.1 - 0.11 11.8 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C4 DnaJ-X PF14308.6 KDO15834.1 - 0.0071 15.8 1.1 0.026 14.0 1.1 1.7 1 1 0 1 1 1 1 X-domain of DnaJ-containing DUF3829 PF12889.7 KDO15834.1 - 0.068 12.6 0.4 0.08 12.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) 14-3-3 PF00244.20 KDO15834.1 - 0.078 12.5 0.2 0.079 12.5 0.2 1.0 1 0 0 1 1 1 0 14-3-3 protein GIT_SHD PF08518.11 KDO15834.1 - 0.23 11.1 1.4 0.49 10.1 1.4 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT BRCT_2 PF16589.5 KDO15837.1 - 3.2e-13 49.9 0.0 6.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO15837.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KDO15837.1 - 2.3e-06 27.4 0.2 4.5e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KDO15837.1 - 1.1e-05 25.6 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS PF00817.20 KDO15837.1 - 0.0039 17.2 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DUF3148 PF11347.8 KDO15837.1 - 0.17 11.7 0.1 1 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) DEC-1_N PF04625.13 KDO15837.1 - 1.1 8.2 4.5 1.5 7.7 4.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase_Tyr PF07714.17 KDO15838.1 - 7.7e-36 123.7 0.0 9.4e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO15838.1 - 1.1e-34 120.0 0.0 1.6e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO15838.1 - 0.00013 20.9 0.0 0.00019 20.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO15838.1 - 0.00066 19.7 0.3 0.0028 17.6 0.2 1.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO15838.1 - 0.00074 18.9 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.14 KDO15838.1 - 0.1 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Kinase-like PF14531.6 KDO15838.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2807 PF10988.8 KDO15839.1 - 6e-17 62.0 12.1 6.1e-12 45.7 8.2 2.3 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain Rieske PF00355.26 KDO15840.1 - 0.00027 20.8 0.3 0.00029 20.7 0.3 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KDO15840.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Ribosomal_S8 PF00410.19 KDO15847.1 - 3e-12 46.6 0.0 3.3e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Cnn_1N PF07989.11 KDO15849.1 - 0.0024 18.0 4.7 2.9 8.1 0.0 2.8 2 1 0 2 2 2 2 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 KDO15849.1 - 0.017 15.0 1.3 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 KDO15849.1 - 0.041 14.0 7.5 1.9 8.6 0.3 2.7 1 1 2 3 3 3 0 bZIP transcription factor Syntaxin-6_N PF09177.11 KDO15849.1 - 0.052 14.1 3.7 0.069 13.7 3.7 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TPD52 PF04201.15 KDO15849.1 - 0.066 12.8 2.8 0.1 12.2 2.8 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Isochorismatase PF00857.20 KDO15849.1 - 0.066 13.4 0.2 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Isochorismatase family FlaC_arch PF05377.11 KDO15849.1 - 0.1 13.0 1.8 0.51 10.8 0.3 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) NEMO PF11577.8 KDO15849.1 - 0.21 11.7 8.2 0.46 10.5 7.7 2.0 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO UPF0242 PF06785.11 KDO15849.1 - 0.4 10.8 14.7 0.53 10.4 12.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KDO15849.1 - 0.71 10.4 17.4 0.96 9.9 1.9 3.1 1 1 1 2 2 2 0 Cell division protein ZapB LIN52 PF10044.9 KDO15849.1 - 0.72 10.6 7.0 7.8 7.3 2.6 2.3 1 1 1 2 2 2 0 Retinal tissue protein Retrotrans_gag PF03732.17 KDO15849.1 - 0.76 10.1 7.4 1.2 9.5 0.6 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein bZIP_2 PF07716.15 KDO15849.1 - 1.9 8.6 16.1 1.9 8.6 3.2 3.3 1 1 3 4 4 4 0 Basic region leucine zipper FAM76 PF16046.5 KDO15849.1 - 1.9 7.7 6.3 2.2 7.5 6.3 1.1 1 0 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 KDO15849.1 - 2.2 8.7 12.3 1.4 9.3 5.2 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 KDO15849.1 - 7.6 6.4 12.7 7.6 6.4 1.7 2.7 1 1 2 3 3 3 0 Septum formation initiator DUF1929 PF09118.11 KDO15851.1 - 4.4 7.7 6.9 0.46 10.8 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1929) ABC_tran PF00005.27 KDO15852.1 - 1.4e-07 32.1 0.0 1.7e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 KDO15852.1 - 0.02 15.1 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KDO15852.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PITH PF06201.13 KDO15854.1 - 2.1e-09 37.8 0.0 2.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Imp-YgjV PF10688.9 KDO15855.1 - 0.079 12.8 0.7 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial inner membrane protein PAN_3 PF08277.12 KDO15855.1 - 0.11 12.3 1.0 0.25 11.2 1.0 1.5 1 0 0 1 1 1 0 PAN-like domain Sugar_tr PF00083.24 KDO15856.1 - 4.8e-16 58.7 12.6 5.4e-16 58.5 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO15856.1 - 1.9e-05 23.8 4.2 2.1e-05 23.6 4.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SNAPc_SNAP43 PF09808.9 KDO15857.1 - 7e-09 35.9 0.2 1e-08 35.3 0.2 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 RIFIN PF02009.16 KDO15858.1 - 3.2 7.5 6.3 3.8 7.3 6.3 1.1 1 0 0 1 1 1 0 Rifin PARM PF17061.5 KDO15858.1 - 7.1 6.7 38.9 8.2 6.5 38.9 1.0 1 0 0 1 1 1 0 PARM MutS_V PF00488.21 KDO15860.1 - 2.4e-38 132.1 0.6 8.9e-37 126.9 0.6 2.1 1 1 0 1 1 1 1 MutS domain V ABC_tran PF00005.27 KDO15860.1 - 0.002 18.6 1.1 0.0036 17.8 0.2 1.8 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 KDO15860.1 - 0.0069 16.1 0.0 0.085 12.6 0.0 2.5 1 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 KDO15860.1 - 0.017 15.4 0.4 0.085 13.1 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO15860.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO15860.1 - 0.036 13.9 0.1 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Defensin_1 PF00323.19 KDO15863.1 - 0.35 11.5 0.6 0.35 11.5 0.6 2.2 2 0 0 2 2 2 0 Mammalian defensin Arrestin_C PF02752.22 KDO15866.1 - 4.1e-11 43.5 0.0 4.6e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Elicitin PF00964.17 KDO15867.1 - 0.0004 20.4 1.9 0.0004 20.4 1.9 2.1 1 1 0 1 1 1 1 Elicitin SART-1 PF03343.13 KDO15870.1 - 3.3e-50 171.3 9.0 3.3e-50 171.3 9.0 2.1 2 0 0 2 2 2 1 SART-1 family Mito_carr PF00153.27 KDO15871.1 - 5e-12 45.6 5.8 3.1e-05 23.8 0.5 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein EGF_2 PF07974.13 KDO15872.1 - 4.3e-09 36.6 43.7 0.00027 21.2 7.1 4.5 4 0 0 4 4 4 4 EGF-like domain EGF PF00008.27 KDO15872.1 - 0.0083 16.4 31.3 0.18 12.2 2.7 4.5 4 0 0 4 4 4 3 EGF-like domain Hydrolase PF00702.26 KDO15873.1 - 2.4e-11 44.3 1.2 3.5e-11 43.8 1.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KDO15873.1 - 3e-05 23.9 0.7 3.7e-05 23.6 0.7 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KDO15874.1 - 1.7e-34 118.1 11.0 6.2e-14 52.2 0.8 3.3 3 0 0 3 3 3 3 Heavy-metal-associated domain Tox-PL-2 PF15643.6 KDO15874.1 - 0.13 12.5 0.8 5.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Papain fold toxin 2 Gp37 PF09646.10 KDO15874.1 - 0.18 11.6 0.2 18 5.2 0.1 2.8 2 1 1 3 3 3 0 Gp37 protein Fer2_BFD PF04324.15 KDO15874.1 - 0.19 12.1 6.0 33 4.9 0.1 4.1 3 1 0 3 3 3 0 BFD-like [2Fe-2S] binding domain DUF1970 PF09301.10 KDO15874.1 - 0.53 10.6 8.2 2.3 8.5 1.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1970) Trypsin_2 PF13365.6 KDO15875.1 - 2.3e-08 35.1 0.1 2.9e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO15875.1 - 0.00051 19.9 1.4 0.00059 19.7 1.4 1.4 1 1 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.13 KDO15875.1 - 0.003 16.8 0.5 0.004 16.4 0.5 1.1 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 KDO15875.1 - 0.01 14.6 0.1 0.024 13.3 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 Peptidase_C4 PF00863.19 KDO15875.1 - 0.034 13.4 0.3 0.078 12.3 0.2 1.6 1 1 1 2 2 2 0 Peptidase family C4 Peptidase_C3 PF00548.20 KDO15875.1 - 0.082 12.8 0.1 0.094 12.6 0.1 1.3 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) Peptidase_S7 PF00949.21 KDO15875.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ERCC4 PF02732.15 KDO15876.1 - 2.4e-18 66.8 0.0 3.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain TPR_2 PF07719.17 KDO15877.1 - 6e-17 60.3 0.1 0.00021 21.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO15877.1 - 5.8e-14 51.5 2.6 1.1e-06 28.2 0.2 3.4 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 KDO15877.1 - 1e-13 50.4 0.1 1.4e-05 24.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO15877.1 - 9.1e-11 41.9 3.9 0.001 19.3 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO15877.1 - 1e-10 41.5 3.5 0.00076 20.1 0.1 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO15877.1 - 7.1e-10 38.3 0.1 0.00024 21.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO15877.1 - 1.1e-09 38.7 13.3 6.3e-06 26.7 1.3 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO15877.1 - 2.9e-07 30.0 2.0 0.011 15.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO15877.1 - 7.9e-07 29.3 0.4 1.4 9.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO15877.1 - 1.4e-06 28.7 2.7 7e-05 23.3 0.9 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO15877.1 - 8.8e-06 25.8 0.1 0.0042 17.4 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO15877.1 - 2.1e-05 24.6 1.8 0.00027 21.0 1.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO15877.1 - 0.00019 21.6 0.1 0.00055 20.1 0.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KDO15877.1 - 0.0003 20.6 8.5 1 9.3 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KDO15877.1 - 0.0034 17.1 0.4 0.011 15.4 0.3 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain Cnd2 PF05786.14 KDO15877.1 - 0.0044 15.8 1.2 0.0045 15.7 1.2 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 TPR_MalT PF17874.1 KDO15877.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region YfiO PF13525.6 KDO15877.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein DNA_pol_phi PF04931.13 KDO15877.1 - 1.3 7.1 12.8 1.5 6.8 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 KDO15877.1 - 1.7 9.4 12.3 2.8 8.7 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 KDO15877.1 - 7.2 4.8 7.8 9.2 4.4 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cation_ATPase PF13246.6 KDO15878.1 - 2e-08 34.2 0.0 1.4e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO15878.1 - 2e-07 31.5 0.0 7.8e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DIM PF08194.12 KDO15878.1 - 0.38 11.0 3.1 0.4 10.9 0.9 2.2 2 0 0 2 2 2 0 DIM protein Glyco_transf_43 PF03360.16 KDO15879.1 - 0.055 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 43 Bac_surface_Ag PF01103.23 KDO15880.1 - 1.1e-05 25.1 0.0 1.2e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Surface antigen Peptidase_C69 PF03577.15 KDO15881.1 - 0.00024 20.2 0.0 0.00026 20.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C69 ACBP PF00887.19 KDO15882.1 - 9.7e-15 54.6 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Cmyb_C PF09316.10 KDO15882.1 - 0.059 13.1 0.2 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 C-myb, C-terminal PH PF00169.29 KDO15884.1 - 1.7e-08 34.9 0.0 2.7e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO15884.1 - 9e-05 22.7 0.1 0.00016 21.9 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO15884.1 - 0.00038 20.8 3.1 0.025 15.0 1.9 2.1 1 1 0 2 2 2 2 Pleckstrin homology domain Pkinase PF00069.25 KDO15886.1 - 8.7e-07 28.6 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2167 PF09935.9 KDO15887.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) SNF2_N PF00176.23 KDO15888.1 - 1e-61 208.6 0.0 1.8e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KDO15888.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit F-box-like PF12937.7 KDO15888.1 - 0.01 15.7 0.2 0.027 14.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KDO15888.1 - 0.046 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 KDO15888.1 - 0.077 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 F-box LRR_6 PF13516.6 KDO15893.1 - 8.2e-23 78.5 7.3 0.25 11.5 0.1 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 KDO15893.1 - 2e-11 43.9 0.1 0.015 15.7 0.0 5.3 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO15893.1 - 4.9e-08 32.6 3.1 0.14 11.9 0.8 5.1 4 2 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KDO15893.1 - 3.4e-05 23.8 0.1 26 5.9 0.0 5.9 6 1 0 6 6 6 1 Leucine Rich Repeat RGS PF00615.19 KDO15894.1 - 7.1e-06 26.3 0.0 3.4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain MatE PF01554.18 KDO15896.1 - 2.9e-29 101.8 44.0 4.4e-18 65.4 14.5 2.9 3 0 0 3 3 3 2 MatE B12D PF06522.11 KDO15897.1 - 9.3e-11 41.4 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PhzC-PhzF PF02567.16 KDO15898.1 - 2.2e-49 168.5 0.0 2.4e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein PIG-H PF10181.9 KDO15899.1 - 8.5e-16 57.6 0.2 1.3e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Peptidase_C78 PF07910.13 KDO15900.1 - 4.1e-43 147.3 0.0 4.8e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KDO15900.1 - 0.012 15.1 0.0 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C54 GCIP PF13324.6 KDO15903.1 - 0.056 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Peptidase_S28 PF05577.12 KDO15905.1 - 6.2e-15 54.9 0.0 6.8e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 MatE PF01554.18 KDO15906.1 - 3.4e-23 82.1 10.5 3.8e-23 81.9 10.5 1.0 1 0 0 1 1 1 1 MatE DUF3566 PF12089.8 KDO15906.1 - 0.047 14.0 1.0 0.047 14.0 1.0 1.6 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Pyridoxal_deC PF00282.19 KDO15908.1 - 0.058 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Hist_deacetyl PF00850.19 KDO15909.1 - 3.8e-81 272.9 0.2 4.3e-81 272.7 0.2 1.0 1 0 0 1 1 1 1 Histone deacetylase domain IF3_C PF00707.22 KDO15910.1 - 8.2e-06 25.7 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain KIAA1430 PF13879.6 KDO15913.1 - 0.00074 20.2 7.2 0.077 13.8 0.2 2.5 2 1 1 3 3 3 2 KIAA1430 homologue C2 PF00168.30 KDO15913.1 - 0.0047 17.2 0.0 0.0098 16.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain TUDOR_5 PF18359.1 KDO15913.1 - 0.0087 15.7 0.2 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF2804 PF10974.8 KDO15914.1 - 1.5e-33 116.7 0.0 1.8e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Ephrin_rec_like PF07699.13 KDO15916.1 - 1.6e-05 24.6 23.0 0.0067 16.2 2.6 3.6 1 1 2 3 3 3 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 KDO15916.1 - 0.2 12.1 18.8 4.5 7.8 1.9 4.1 2 1 2 4 4 4 0 TNFR/NGFR cysteine-rich region Sp38 PF07354.12 KDO15916.1 - 2.4 7.5 19.5 0.47 9.9 3.6 2.9 1 1 2 3 3 3 0 Zona-pellucida-binding protein (Sp38) FA_hydroxylase PF04116.13 KDO15919.1 - 7.3e-17 62.0 17.5 7.3e-17 62.0 17.5 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily tRNA_anti-codon PF01336.25 KDO15920.1 - 2.1e-05 24.4 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 KDO15920.1 - 0.00011 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 RMI2 PF16100.5 KDO15920.1 - 0.00051 19.9 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 DUF1285 PF06938.11 KDO15920.1 - 0.061 13.3 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) EBV-NA3 PF05009.12 KDO15921.1 - 1.4 8.3 3.5 1.4 8.4 3.5 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Clat_adaptor_s PF01217.20 KDO15922.1 - 1.2e-50 171.1 0.2 1.3e-50 171.0 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MIT PF04212.18 KDO15923.1 - 8.8e-24 83.4 0.4 1.2e-23 82.9 0.4 1.2 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain USP8_dimer PF08969.11 KDO15923.1 - 0.063 13.5 1.5 0.15 12.2 1.5 1.7 1 1 0 1 1 1 0 USP8 dimerisation domain AAA PF00004.29 KDO15924.1 - 9.4e-44 149.0 0.0 1.1e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KDO15924.1 - 1.8e-06 28.0 0.0 1.8e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO15924.1 - 2e-06 27.6 0.0 2.6e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KDO15924.1 - 4.5e-06 27.1 0.0 0.00055 20.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO15924.1 - 1.2e-05 25.7 0.1 0.0048 17.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO15924.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KDO15924.1 - 5.7e-05 23.2 0.0 8.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KDO15924.1 - 0.00011 22.4 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KDO15924.1 - 0.00032 20.5 0.0 0.00052 19.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO15924.1 - 0.0004 20.9 0.1 0.00079 20.0 0.0 1.5 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KDO15924.1 - 0.00061 20.0 0.0 0.0009 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KDO15924.1 - 0.00063 19.1 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KDO15924.1 - 0.00065 20.1 0.0 0.00096 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ATPase PF06745.13 KDO15924.1 - 0.0012 18.3 0.1 0.42 9.9 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 KDO15924.1 - 0.0019 17.8 0.1 0.3 10.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 KDO15924.1 - 0.0034 17.8 0.0 0.0053 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KDO15924.1 - 0.0044 16.2 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KDO15924.1 - 0.0073 15.8 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KDO15924.1 - 0.0084 15.4 0.1 0.58 9.4 0.1 2.2 1 1 1 2 2 2 1 Zeta toxin NACHT PF05729.12 KDO15924.1 - 0.0092 15.9 0.0 0.27 11.1 0.0 2.1 1 1 1 2 2 2 1 NACHT domain ATPase_2 PF01637.18 KDO15924.1 - 0.01 15.7 0.0 0.6 10.0 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KDO15924.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KDO15924.1 - 0.019 14.7 0.0 0.15 11.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 KDO15924.1 - 0.024 14.0 0.0 6.2 6.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein KAP_NTPase PF07693.14 KDO15924.1 - 0.031 13.5 0.0 0.98 8.6 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Guanylate_kin PF00625.21 KDO15924.1 - 0.039 13.7 0.0 0.83 9.3 0.0 2.1 1 1 0 2 2 2 0 Guanylate kinase PhoH PF02562.16 KDO15924.1 - 0.041 13.3 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 KDO15924.1 - 0.041 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 KDO15924.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KDO15924.1 - 0.062 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KDO15924.1 - 0.081 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Torsin CPT PF07931.12 KDO15924.1 - 0.084 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zot PF05707.12 KDO15924.1 - 0.1 12.2 0.2 1.9 8.1 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Bac_DnaA PF00308.18 KDO15924.1 - 0.12 12.2 0.0 0.57 10.0 0.0 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_21 PF13304.6 KDO15924.1 - 0.15 11.9 0.3 2.1 8.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 KDO15924.1 - 0.18 11.7 0.1 6.1 6.7 0.0 2.1 1 1 1 2 2 2 0 NTPase DUF2075 PF09848.9 KDO15924.1 - 0.18 11.0 0.0 0.38 9.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HK PF02110.15 KDO15925.1 - 0.14 11.6 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family zf-C2H2 PF00096.26 KDO15926.1 - 6.9e-18 64.0 31.2 1.7e-05 25.0 1.0 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO15926.1 - 1e-15 57.0 25.2 0.0013 19.4 1.9 5.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO15926.1 - 3e-12 46.3 29.8 0.00025 21.3 2.0 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KDO15926.1 - 2.1e-05 24.1 20.3 0.2 11.4 0.3 5.0 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KDO15926.1 - 3.6e-05 24.0 12.4 0.0064 16.8 1.6 2.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 KDO15926.1 - 0.0035 18.0 11.5 0.021 15.5 1.0 2.3 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 KDO15926.1 - 0.18 11.9 12.5 0.6 10.2 0.0 3.5 2 2 2 4 4 4 0 Aberrant zinc-finger DUF5579 PF17742.1 KDO15926.1 - 0.28 10.7 2.3 3.5 7.1 0.2 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5579) FOXP-CC PF16159.5 KDO15926.1 - 0.93 10.2 7.8 28 5.5 0.1 3.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KDO15926.1 - 5.3 7.2 26.0 0.059 13.4 4.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Tub PF01167.18 KDO15929.1 - 2.4e-59 201.0 0.2 2.9e-59 200.8 0.2 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 KDO15929.1 - 0.00042 20.0 1.3 0.00083 19.0 0.1 2.0 2 1 0 3 3 3 1 Domain of unknown function (DUF3527) Nsp1_C PF05064.13 KDO15930.1 - 6.6e-19 67.8 3.2 6.6e-19 67.8 3.2 2.1 2 0 0 2 2 2 1 Nsp1-like C-terminal region Rad9 PF04139.13 KDO15930.1 - 0.19 11.1 1.5 0.56 9.6 0.3 1.9 1 1 1 2 2 2 0 Rad9 LMBR1 PF04791.16 KDO15930.1 - 0.24 10.2 3.8 0.32 9.9 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Snapin_Pallidin PF14712.6 KDO15930.1 - 0.29 11.6 8.1 1.3 9.5 0.7 2.7 1 1 1 2 2 2 0 Snapin/Pallidin Nucleoporin_FG2 PF15967.5 KDO15930.1 - 0.34 9.4 18.2 0.66 8.5 18.2 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF4164 PF13747.6 KDO15930.1 - 0.42 10.9 7.0 0.49 10.7 0.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Spc24 PF08286.11 KDO15930.1 - 1.9 8.7 9.8 8.3 6.7 2.0 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 KDO15930.1 - 2.1 8.4 7.9 4.7 7.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KDO15930.1 - 4.4 7.5 7.4 6.5 6.9 3.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TF_Zn_Ribbon PF08271.12 KDO15931.1 - 0.0074 15.8 3.6 0.12 11.9 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-HIT PF04438.16 KDO15931.1 - 0.12 12.3 1.0 0.12 12.3 1.0 2.7 2 1 0 2 2 2 0 HIT zinc finger zinc_ribbon_2 PF13240.6 KDO15931.1 - 0.61 9.9 11.7 5.8 6.8 0.7 3.6 3 1 0 3 3 3 0 zinc-ribbon domain PolC_DP2 PF03833.13 KDO15931.1 - 0.61 7.9 1.7 0.66 7.8 1.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf_UBZ PF18439.1 KDO15931.1 - 2.1 8.0 8.3 4 7.1 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger EMP24_GP25L PF01105.24 KDO15932.1 - 1.7e-05 24.8 0.1 1.7e-05 24.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sars6 PF12133.8 KDO15932.1 - 0.13 12.2 0.1 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus DSPc PF00782.20 KDO15934.1 - 5.9e-17 61.7 0.0 8.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO15934.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO15934.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KDO15934.1 - 0.032 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 KDO15934.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase2 PF03162.13 KDO15934.1 - 0.22 11.1 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family RRM_1 PF00076.22 KDO15935.1 - 1.2e-32 111.6 0.0 3.9e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO15935.1 - 2.3e-09 37.2 0.0 0.00051 20.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO15935.1 - 3.7e-05 23.6 0.1 0.26 11.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KDO15935.1 - 0.00086 19.2 0.0 0.095 12.7 0.0 2.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KDO15935.1 - 0.0041 17.4 0.9 5 7.3 0.0 3.6 2 2 2 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter TFIIF_alpha PF05793.12 KDO15935.1 - 0.021 13.4 7.2 0.024 13.3 7.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_TAC_13 PF16459.5 KDO15935.1 - 0.073 13.5 0.0 9.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone, TAC YL1 PF05764.13 KDO15935.1 - 0.21 11.7 5.2 0.25 11.4 5.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PIH1_CS PF18201.1 KDO15936.1 - 2.6e-10 40.6 0.0 7.4e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain Aldedh PF00171.22 KDO15937.1 - 0.00051 18.7 0.1 0.00054 18.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF362 PF04015.12 KDO15937.1 - 0.16 12.2 0.1 0.22 11.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF362) Glyco_hydro38C2 PF17677.1 KDO15938.1 - 0.0092 16.1 0.0 0.036 14.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_transf_8 PF01501.20 KDO15939.1 - 0.00022 20.8 0.3 0.24 10.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KDO15939.1 - 0.0085 15.5 0.1 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative LXG PF04740.12 KDO15940.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Gag_p10 PF02337.17 KDO15940.1 - 0.028 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral GAG p10 protein Methyltransf_23 PF13489.6 KDO15941.1 - 1.6e-05 24.8 0.0 2.3e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO15941.1 - 8.7e-05 22.0 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO15941.1 - 0.0013 19.3 0.8 0.003 18.2 0.8 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO15941.1 - 0.0029 18.2 0.5 0.0056 17.3 0.5 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO15941.1 - 0.007 15.9 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KDO15941.1 - 0.0088 15.8 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO15941.1 - 0.0091 15.3 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KDO15941.1 - 0.049 12.5 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 KDO15941.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.6 1 1 1 2 2 2 0 Tellurite resistance protein TehB MetW PF07021.12 KDO15941.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KDO15941.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MatE PF01554.18 KDO15942.1 - 5.5e-29 100.9 29.5 1.8e-16 60.2 10.0 2.3 2 0 0 2 2 2 2 MatE Fumarate_red_C PF02300.17 KDO15944.1 - 0.097 12.8 0.4 0.097 12.8 0.4 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit C Myticin-prepro PF10690.9 KDO15944.1 - 2.4 8.5 10.0 0.064 13.5 1.4 2.5 2 1 1 3 3 3 0 Myticin pre-proprotein from the mussel ATP-synt_C PF00137.21 KDO15945.1 - 2.2e-28 98.4 32.6 8.4e-15 54.9 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1869 PF08956.10 KDO15945.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) SLATT_5 PF18160.1 KDO15945.1 - 0.61 9.4 1.6 0.7 9.2 0.0 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PEX11 PF05648.14 KDO15950.1 - 1.5e-12 47.5 0.1 1.8e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ANAPC4_WD40 PF12894.7 KDO15951.1 - 2.1e-05 24.7 0.0 1.4 9.3 0.0 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO15951.1 - 0.005 17.6 0.1 5.7 8.0 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat GxDLY PF14607.6 KDO15951.1 - 0.023 14.5 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type LRR_8 PF13855.6 KDO15952.1 - 1.3e-08 34.5 6.3 1e-06 28.4 2.2 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO15952.1 - 7e-08 32.7 7.0 0.0096 16.3 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO15952.1 - 2.5e-06 27.1 2.4 0.86 9.8 0.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 KDO15952.1 - 0.027 15.0 7.0 7 7.6 0.2 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 KDO15952.1 - 0.052 13.1 0.2 0.14 11.6 0.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeat zf-CCCH PF00642.24 KDO15953.1 - 0.028 14.4 1.3 0.061 13.3 0.5 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SHR-BD PF06650.12 KDO15955.1 - 7.4e-25 87.8 0.0 1.5e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KDO15955.1 - 5.8e-08 32.7 0.3 1.1e-07 31.8 0.3 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 KDO15955.1 - 0.00051 19.0 0.0 0.00097 18.1 0.0 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain FA_desaturase PF00487.24 KDO15957.1 - 1.4e-23 84.0 5.4 1.7e-23 83.7 5.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Peptidase_C1 PF00112.23 KDO15958.1 - 1.6e-07 31.7 0.1 1.9e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease MFS_1 PF07690.16 KDO15959.1 - 0.0056 15.6 0.1 0.0066 15.4 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CAP59_mtransfer PF11735.8 KDO15960.1 - 3.4e-10 40.0 0.0 4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PGF-CTERM PF18204.1 KDO15960.1 - 0.24 11.4 1.7 0.46 10.5 1.7 1.5 1 0 0 1 1 1 0 PGF-CTERM motif 2OG-FeII_Oxy_3 PF13640.6 KDO15962.1 - 1.6e-09 38.5 0.0 0.00024 21.9 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KDO15962.1 - 0.0067 16.9 0.0 0.043 14.3 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PLCC PF14466.6 KDO15962.1 - 0.2 11.8 0.0 4.5 7.4 0.0 2.2 2 0 0 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein MFS_1 PF07690.16 KDO15963.1 - 2.7e-20 72.6 31.0 2.7e-20 72.6 31.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily LMBR1 PF04791.16 KDO15964.1 - 1e-41 143.5 27.4 9.5e-39 133.7 27.4 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein C2 PF00168.30 KDO15965.1 - 0.0018 18.6 0.6 0.012 15.8 0.1 2.1 2 0 0 2 2 2 1 C2 domain Peptidase_M14 PF00246.24 KDO15966.1 - 2.5e-08 34.1 0.0 1.1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase Ion_trans_2 PF07885.16 KDO15967.1 - 0.00073 19.4 1.7 0.0011 18.8 1.7 1.3 1 0 0 1 1 1 1 Ion channel PhoR PF11808.8 KDO15967.1 - 1.1 9.7 4.1 11 6.5 0.0 2.9 2 1 1 3 3 3 0 Phosphate regulon sensor protein PhoR DHHC PF01529.20 KDO15968.1 - 0.005 16.9 6.1 0.0064 16.6 6.1 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DuoxA PF10204.9 KDO15968.1 - 1.6 7.7 8.7 1.8 7.5 8.7 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor SlyX PF04102.12 KDO15971.1 - 0.0091 16.6 0.2 0.011 16.4 0.2 1.1 1 0 0 1 1 1 1 SlyX WD40 PF00400.32 KDO15973.1 - 1.9e-05 25.3 0.1 0.0062 17.4 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO15973.1 - 0.0057 16.9 0.0 0.091 13.1 0.0 2.3 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Importin_rep PF18773.1 KDO15973.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Importin 13 repeat His_Phos_1 PF00300.22 KDO15974.1 - 2.6e-32 112.1 1.0 2.9e-32 111.9 1.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Proteasome PF00227.26 KDO15975.1 - 2.2e-58 196.9 0.1 3.1e-58 196.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO15975.1 - 7.8e-14 51.0 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2110 PF09883.9 KDO15975.1 - 0.09 12.4 0.4 0.36 10.4 0.1 2.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) CBFD_NFYB_HMF PF00808.23 KDO15976.1 - 0.039 14.2 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GST_C_4 PF14834.6 KDO15977.1 - 0.16 12.3 2.5 0.8 10.1 1.3 2.4 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF1515 PF07439.11 KDO15978.1 - 0.06 13.4 0.1 0.063 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CCDC85 PF10226.9 KDO15978.1 - 0.078 12.7 0.1 0.13 11.9 0.1 1.3 1 1 0 1 1 1 0 CCDC85 family Hexapep PF00132.24 KDO15979.1 - 0.00011 21.8 0.1 0.00014 21.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) ATG16 PF08614.11 KDO15981.1 - 0.0061 16.8 11.7 0.0061 16.8 11.7 3.1 2 2 1 3 3 3 1 Autophagy protein 16 (ATG16) YjfB_motility PF14070.6 KDO15981.1 - 0.052 13.7 4.0 0.094 12.9 0.8 2.5 2 0 0 2 2 2 0 Putative motility protein DUF3810 PF12725.7 KDO15981.1 - 0.13 11.5 1.6 0.24 10.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ESM4 PF15952.5 KDO15981.1 - 0.17 12.3 5.3 0.31 11.4 5.3 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family MitMem_reg PF13012.6 KDO15981.1 - 1.5 9.3 7.5 8.2 6.9 7.5 2.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Occludin_ELL PF07303.13 KDO15981.1 - 5.1 7.9 7.7 2.1 9.1 1.8 2.9 1 1 2 3 3 3 0 Occludin homology domain Csm1_N PF18504.1 KDO15981.1 - 5.2 7.5 22.2 3.9 7.9 0.1 5.2 4 2 1 5 5 5 0 Csm1 N-terminal domain Fib_alpha PF08702.10 KDO15981.1 - 6.9 6.8 9.3 8.8 6.5 7.4 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 KDO15983.1 - 1.5e-43 149.1 0.0 2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO15983.1 - 1.3e-42 145.9 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO15983.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2207 PF09972.9 KDO15983.1 - 0.043 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) APH PF01636.23 KDO15983.1 - 0.14 12.0 0.0 0.51 10.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO15983.1 - 0.21 10.5 0.0 2.7 6.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain DUF1180 PF06679.12 KDO15983.1 - 0.74 10.2 0.1 0.74 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Beta-APP PF03494.13 KDO15983.1 - 1.1 9.2 2.7 2.1 8.3 2.7 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) AMP-binding PF00501.28 KDO15984.1 - 4e-17 61.9 0.0 9.1e-17 60.7 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Tudor_4 PF18358.1 KDO15989.1 - 0.076 12.6 0.1 0.69 9.6 0.1 2.4 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain CSTF_C PF14304.6 KDO15990.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal PapD-like PF14874.6 KDO15993.1 - 1e-05 25.6 0.0 0.0098 16.0 0.0 2.3 2 0 0 2 2 2 2 Flagellar-associated PapD-like ASH PF15780.5 KDO15993.1 - 6.5e-05 23.1 0.0 0.035 14.3 0.0 3.1 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF2383 PF09537.10 KDO15993.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Pkinase PF00069.25 KDO15994.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain TPR_10 PF13374.6 KDO15995.1 - 0.00088 19.1 0.1 0.62 10.0 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TAF6_C PF07571.13 KDO15995.1 - 0.013 15.8 0.4 0.034 14.5 0.1 1.8 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain TPR_12 PF13424.6 KDO15995.1 - 0.04 14.2 0.1 3.3 8.1 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Rubis-subs-bind PF09273.11 KDO15996.1 - 1.4e-13 51.7 0.0 2.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Peptidase_C3 PF00548.20 KDO15997.1 - 0.037 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) LisH_2 PF16045.5 KDO16000.1 - 0.15 11.1 0.2 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 LisH PLRV_ORF5 PF01690.17 KDO16003.1 - 1.2 7.8 2.6 1.8 7.2 2.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FA_hydroxylase PF04116.13 KDO16004.1 - 3.5e-05 24.2 7.3 3.5e-05 24.2 7.3 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ank_2 PF12796.7 KDO16005.1 - 1.3e-06 28.9 0.1 1.7e-05 25.3 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO16005.1 - 0.00065 20.0 0.7 0.012 15.9 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16005.1 - 0.00095 19.4 0.1 0.18 12.5 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KDO16005.1 - 0.0021 18.6 0.1 0.032 14.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ApoLp-III PF07464.11 KDO16006.1 - 0.002 18.3 3.0 0.0029 17.7 3.0 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) RasGAP_C PF03836.15 KDO16006.1 - 0.027 14.6 0.3 0.047 13.8 0.3 1.4 1 0 0 1 1 1 0 RasGAP C-terminus bZIP_2 PF07716.15 KDO16006.1 - 0.03 14.4 1.2 0.068 13.3 1.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 KDO16006.1 - 0.033 14.4 0.5 0.064 13.5 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper M PF02370.16 KDO16006.1 - 0.092 13.3 2.7 0.12 13.0 0.3 2.6 3 0 0 3 3 3 0 M protein repeat Ion_trans PF00520.31 KDO16006.1 - 0.17 11.1 0.6 0.23 10.6 0.6 1.2 1 0 0 1 1 1 0 Ion transport protein DUF1039 PF06287.11 KDO16006.1 - 0.26 11.8 3.5 6.5 7.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1039) DUF3138 PF11336.8 KDO16006.1 - 0.38 9.3 4.5 0.52 8.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CLZ PF16526.5 KDO16006.1 - 0.79 10.1 4.5 0.42 11.0 1.2 2.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GIT_CC PF16559.5 KDO16006.1 - 2.6 8.0 7.0 0.85 9.5 3.8 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3652 PF12372.8 KDO16007.1 - 0.14 12.1 0.2 0.39 10.7 0.2 1.8 1 0 0 1 1 1 0 Huntingtin protein region KIX_2 PF16987.5 KDO16009.1 - 2e-10 40.5 2.3 2.2e-10 40.4 2.3 1.0 1 0 0 1 1 1 1 KIX domain RGS PF00615.19 KDO16010.1 - 1.8e-37 128.2 1.8 5e-18 65.5 0.2 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain YkyB PF14177.6 KDO16010.1 - 0.021 15.1 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 YkyB-like protein EF-hand_1 PF00036.32 KDO16011.1 - 1.6e-09 36.6 2.0 4.6e-06 25.8 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO16011.1 - 1.7e-07 31.5 0.5 3e-07 30.8 0.2 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO16011.1 - 6.4e-07 28.6 1.6 0.0047 16.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO16011.1 - 1.7e-06 27.5 1.7 0.0003 20.5 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO16011.1 - 4e-05 23.4 2.3 0.0018 18.1 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair ABC_membrane PF00664.23 KDO16012.1 - 1.8e-08 34.3 13.8 2.5e-08 33.9 13.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO16012.1 - 1.6e-05 25.4 0.2 3.2e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 KDO16012.1 - 0.0023 18.0 0.6 0.0037 17.4 0.6 1.3 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KDO16012.1 - 0.0064 16.4 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO16012.1 - 0.011 15.5 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KDO16012.1 - 0.022 14.2 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 KDO16012.1 - 0.03 13.5 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KDO16012.1 - 0.043 13.9 0.2 0.095 12.8 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO16012.1 - 0.076 13.4 1.3 0.13 12.7 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KDO16012.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO16012.1 - 0.14 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KDO16012.1 - 0.15 11.6 0.2 0.33 10.5 0.2 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain YjcB PF15940.5 KDO16012.1 - 0.26 11.5 4.1 0.21 11.8 1.6 2.2 2 0 0 2 2 2 0 Family of unknown function Acyl_transf_3 PF01757.22 KDO16013.1 - 6.9e-05 22.1 2.7 0.00011 21.4 2.7 1.3 1 1 0 1 1 1 1 Acyltransferase family PAN_4 PF14295.6 KDO16014.1 - 0.00036 20.4 10.3 0.0012 18.7 2.8 2.2 2 0 0 2 2 2 2 PAN domain Dickkopf_N PF04706.12 KDO16014.1 - 0.067 13.7 2.1 0.067 13.7 2.1 2.0 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Lustrin_cystein PF14625.6 KDO16014.1 - 0.086 13.2 1.8 0.086 13.2 1.8 2.2 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain CarbpepA_inh PF02977.15 KDO16014.1 - 0.78 9.6 8.9 0.3 10.9 2.6 2.3 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor SAM_2 PF07647.17 KDO16016.1 - 0.017 15.2 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KDO16016.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF4203 PF13886.6 KDO16018.1 - 0.00013 21.8 7.4 0.00013 21.8 7.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) OATP PF03137.20 KDO16018.1 - 0.015 13.6 0.4 0.017 13.4 0.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3382 PF11862.8 KDO16018.1 - 3.3 8.1 8.6 11 6.3 4.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Myb_DNA-binding PF00249.31 KDO16019.1 - 0.0054 16.9 0.0 3.9 7.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Cript PF10235.9 KDO16020.1 - 9.7 6.8 12.5 5.4 7.7 8.5 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Ion_trans PF00520.31 KDO16021.1 - 1.6e-81 273.2 18.6 6.3e-43 146.8 10.3 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KDO16021.1 - 4.9e-06 25.5 27.4 0.0016 17.2 0.9 5.1 5 0 0 5 5 5 5 Polycystin cation channel Pkinase_Tyr PF07714.17 KDO16022.1 - 1.7e-23 83.3 0.0 1e-19 70.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO16022.1 - 3.8e-22 78.9 0.0 3.9e-20 72.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Abhydrolase_1 PF00561.20 KDO16024.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO16024.1 - 0.0047 17.6 0.4 0.0051 17.5 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MukB_hinge PF16330.5 KDO16024.1 - 0.21 11.3 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 MukB hinge domain ubiquitin PF00240.23 KDO16025.1 - 0.00047 19.9 0.4 0.0035 17.1 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin family Scaffolding_pro PF11418.8 KDO16026.1 - 0.017 15.7 1.7 0.66 10.6 0.3 2.6 1 1 1 2 2 2 0 Phi29 scaffolding protein APC_N_CC PF16689.5 KDO16026.1 - 0.07 13.2 3.2 5.1 7.2 0.3 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Swi5 PF07061.11 KDO16026.1 - 0.71 10.0 0.1 0.71 10.0 0.1 3.2 3 1 0 3 3 3 0 Swi5 YabA PF06156.13 KDO16026.1 - 1 10.0 12.2 0.19 12.4 2.2 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Ricin_B_lectin PF00652.22 KDO16027.1 - 7.3e-25 87.7 17.3 1.6e-12 47.8 4.4 3.1 2 1 0 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO16027.1 - 5.7e-14 52.6 16.5 0.0015 19.2 0.9 4.3 2 2 1 4 4 4 4 Ricin-type beta-trefoil lectin domain-like HHH_3 PF12836.7 KDO16028.1 - 0.00026 21.2 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 KDO16028.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Epimerase PF01370.21 KDO16029.1 - 3e-19 69.4 0.1 3.3e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO16029.1 - 1.9e-13 50.7 0.1 2.2e-13 50.5 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KDO16029.1 - 5.2e-13 48.8 0.6 1.4e-05 24.4 0.2 2.0 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KDO16029.1 - 6.9e-11 42.1 0.1 7.8e-11 42.0 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KDO16029.1 - 9e-11 41.3 0.0 1e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KDO16029.1 - 1.4e-09 37.5 0.4 8.1e-09 35.0 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO16029.1 - 4.8e-09 35.7 0.1 5.8e-09 35.5 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KDO16029.1 - 1.1e-08 34.9 0.0 1.3e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KDO16029.1 - 0.00015 22.0 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KDO16029.1 - 0.00056 19.4 0.0 0.0007 19.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO16029.1 - 0.0068 16.3 0.5 0.013 15.4 0.5 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KDO16029.1 - 0.04 14.2 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3694 PF12473.8 KDO16030.1 - 5.8e-06 27.0 1.4 3.7e-05 24.4 0.6 2.4 2 1 0 2 2 2 1 Kinesin protein ABC_membrane PF00664.23 KDO16031.1 - 2.5e-13 50.3 0.0 2.9e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region LRR_6 PF13516.6 KDO16032.1 - 0.0013 18.6 0.1 0.005 16.8 0.0 1.8 2 0 0 2 2 2 1 Leucine Rich repeat FANC_SAP PF18081.1 KDO16033.1 - 3.9 7.7 7.1 7 6.9 0.1 3.0 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain Prenyltrans PF00432.21 KDO16034.1 - 1.2e-15 56.9 0.4 1.8e-05 24.3 0.0 3.2 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Castor_Poll_mid PF06241.12 KDO16036.1 - 1.3e-25 89.4 0.0 3.1e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel GBP PF02263.19 KDO16037.1 - 1.8e-52 178.2 1.2 1e-41 142.9 0.1 2.1 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 KDO16037.1 - 0.15 12.4 0.5 1.2 9.5 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain NOA36 PF06524.12 KDO16037.1 - 1.9 7.8 7.3 3.7 6.8 7.3 1.4 1 0 0 1 1 1 0 NOA36 protein Peptidase_S8 PF00082.22 KDO16039.1 - 1.8e-34 119.3 0.4 2.5e-34 118.9 0.4 1.2 1 0 0 1 1 1 1 Subtilase family ECR1_N PF14382.6 KDO16039.1 - 0.0029 17.4 0.1 0.54 10.1 0.0 3.1 3 0 0 3 3 3 2 Exosome complex exonuclease RRP4 N-terminal region NuA4 PF09340.10 KDO16042.1 - 7.6e-14 51.3 0.0 1.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Glycoprotein_G PF00802.19 KDO16042.1 - 0.55 9.5 4.3 0.86 8.9 4.3 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G RRN3 PF05327.11 KDO16045.1 - 0.0048 15.5 2.9 0.0055 15.3 2.9 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 KDO16045.1 - 0.0099 15.6 0.8 0.013 15.2 0.8 1.2 1 0 0 1 1 1 1 FAM176 family BUD22 PF09073.10 KDO16045.1 - 0.033 13.5 3.5 0.033 13.5 3.5 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KDO16045.1 - 0.074 12.4 19.0 0.094 12.0 19.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KDO16045.1 - 0.15 10.1 16.6 0.18 9.8 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 KDO16045.1 - 0.23 11.5 7.3 0.35 10.9 7.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2722 PF10846.8 KDO16045.1 - 0.25 10.2 1.1 0.2 10.6 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sigma70_ner PF04546.13 KDO16045.1 - 0.27 11.1 13.5 0.3 11.0 13.5 1.2 1 1 0 1 1 1 0 Sigma-70, non-essential region Utp14 PF04615.13 KDO16045.1 - 0.27 9.8 5.4 0.33 9.5 5.4 1.1 1 0 0 1 1 1 0 Utp14 protein GCIP PF13324.6 KDO16045.1 - 0.58 9.7 5.2 0.63 9.6 5.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 KDO16045.1 - 1.2 7.3 12.0 1.4 7.1 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Rhabdo_ncap PF00945.18 KDO16045.1 - 1.3 7.8 4.0 1.6 7.5 4.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cwf_Cwc_15 PF04889.12 KDO16045.1 - 2.9 7.6 19.8 3.9 7.2 19.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 KDO16045.1 - 3.1 6.8 24.9 3.9 6.5 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KDO16045.1 - 4.1 6.7 12.3 5.3 6.4 12.3 1.1 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 KDO16045.1 - 8 6.9 18.1 18 5.8 18.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BAR PF03114.18 KDO16046.1 - 0.003 17.2 2.1 0.0047 16.6 1.9 1.6 1 1 0 1 1 1 1 BAR domain DUF3128 PF11326.8 KDO16048.1 - 6.7e-16 58.4 0.2 1.6e-15 57.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) START PF01852.19 KDO16048.1 - 2.6e-07 30.3 0.1 4.2e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO16048.1 - 0.084 13.1 9.0 0.18 12.0 9.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KDO16048.1 - 7.8 6.7 23.1 19 5.5 22.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger RabGAP-TBC PF00566.18 KDO16049.1 - 1.9e-44 151.9 1.1 5.7e-43 147.1 0.5 2.0 2 0 0 2 2 2 2 Rab-GTPase-TBC domain AAA_lid_3 PF17862.1 KDO16050.1 - 8.1e-14 51.2 0.4 1.3e-13 50.5 0.4 1.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KDO16050.1 - 1.1e-10 42.1 0.0 2.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Tegument_dsDNA PF12818.7 KDO16051.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.0 1 0 0 1 1 1 0 dsDNA viral tegument protein Ank PF00023.30 KDO16052.1 - 1.8e-16 59.7 0.3 4.9e-05 23.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KDO16052.1 - 2.5e-16 60.0 0.0 4.1e-07 30.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16052.1 - 4e-14 52.8 0.1 7.8e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16052.1 - 2.5e-13 48.9 0.1 0.00068 19.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KDO16052.1 - 6.8e-13 48.6 0.1 6.3e-05 23.2 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) HOIP-UBA PF16678.5 KDO16052.1 - 0.011 15.8 0.2 0.044 13.8 0.2 2.1 1 1 0 1 1 1 0 HOIP UBA domain pair Ank_2 PF12796.7 KDO16053.1 - 4.1e-18 65.7 14.5 4e-05 24.1 0.4 5.9 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16053.1 - 1.9e-13 50.6 13.0 0.039 14.5 0.3 7.0 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16053.1 - 1.7e-08 34.1 14.5 0.41 11.4 0.0 10.7 12 0 0 12 12 12 1 Ankyrin repeat Ank_5 PF13857.6 KDO16053.1 - 5.6e-07 29.7 20.0 5.8 7.4 0.0 9.0 3 1 7 10 10 10 4 Ankyrin repeats (many copies) DUF5049 PF16468.5 KDO16053.1 - 0.0018 18.1 0.0 2.8 7.9 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF5049) HTH_22 PF13309.6 KDO16053.1 - 0.08 13.0 0.0 7.9 6.6 0.0 3.2 3 1 0 3 3 3 0 HTH domain Ank PF00023.30 KDO16053.1 - 0.082 13.4 15.6 16 6.1 0.2 7.4 5 3 1 6 6 6 0 Ankyrin repeat BTG PF07742.12 KDO16054.1 - 0.027 14.3 0.2 0.034 14.0 0.2 1.2 1 0 0 1 1 1 0 BTG family DUF2423 PF10338.9 KDO16054.1 - 4.3 7.6 6.7 4.5e+02 1.2 6.7 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2423) DNA_pol_E_B PF04042.16 KDO16056.1 - 7.4e-37 126.7 0.2 1.1e-36 126.1 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 KDO16056.1 - 0.0018 18.5 0.1 0.0045 17.2 0.1 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF3228 PF11539.8 KDO16056.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Ricin_B_lectin PF00652.22 KDO16057.1 - 7.3e-13 48.9 7.0 9.8e-07 29.1 0.4 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO16057.1 - 1.6e-05 25.5 3.7 0.027 15.2 0.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF2154 PF09922.9 KDO16059.1 - 8.8e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF Mor PF08765.11 KDO16059.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family MIP PF00230.20 KDO16060.1 - 2e-26 93.1 2.8 2.5e-26 92.8 2.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1418 PF07214.12 KDO16060.1 - 0.064 13.1 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) PRORP PF16953.5 KDO16064.1 - 2.6e-23 82.8 1.1 2.9e-23 82.7 1.1 1.0 1 0 0 1 1 1 1 Protein-only RNase P RNase_Zc3h12a PF11977.8 KDO16064.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain DUF423 PF04241.15 KDO16066.1 - 3.7 7.8 6.5 8.2 6.7 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DSBA PF01323.20 KDO16067.1 - 0.036 13.8 0.1 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain MCR_beta PF02241.18 KDO16069.1 - 0.033 13.8 0.2 0.079 12.5 0.2 1.6 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain E1_dh PF00676.20 KDO16070.1 - 9.5e-51 172.5 0.0 1.3e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KDO16070.1 - 6.3e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain MatE PF01554.18 KDO16071.1 - 1.1e-30 106.5 37.3 2e-18 66.5 15.1 2.3 2 0 0 2 2 2 2 MatE TPR_1 PF00515.28 KDO16072.1 - 3.9e-08 32.8 0.0 0.0021 17.8 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16072.1 - 9e-06 26.2 0.0 1.8e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16072.1 - 6.9e-05 22.7 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO16072.1 - 0.002 18.2 0.0 0.0062 16.7 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO16072.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO16072.1 - 0.017 15.3 0.0 5.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO16072.1 - 0.022 14.4 0.0 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 TPR repeat TPR_14 PF13428.6 KDO16072.1 - 0.067 14.0 0.0 4.1 8.5 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO16072.1 - 0.069 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HECT PF00632.25 KDO16073.1 - 1.5e-56 192.1 0.0 2.6e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) EF-hand_7 PF13499.6 KDO16073.1 - 4.6e-10 39.8 0.7 1.5e-05 25.3 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO16073.1 - 9e-08 31.5 0.0 0.0058 16.5 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KDO16073.1 - 8.4e-05 21.9 0.0 0.46 10.2 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KDO16073.1 - 0.046 14.0 0.1 4.2 7.8 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KDO16074.1 - 5.5e-18 63.1 1.4 1.5e-06 27.3 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KDO16074.1 - 5.8e-17 61.9 2.4 1.1e-08 35.4 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO16074.1 - 5e-16 57.2 5.1 2e-06 27.3 0.4 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KDO16074.1 - 1.5e-11 44.0 0.6 0.0001 22.1 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KDO16074.1 - 8.4e-08 32.4 0.4 4.3e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO16074.1 - 9.2e-08 31.3 1.8 0.023 14.2 0.0 3.5 3 1 0 3 3 3 2 EF hand DnaG_DnaB_bind PF08278.11 KDO16074.1 - 0.017 15.7 0.5 0.24 12.0 0.1 2.0 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding EF-hand_4 PF12763.7 KDO16074.1 - 0.044 13.7 0.7 0.66 10.0 0.1 2.4 2 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Beta-lactamase2 PF13354.6 KDO16074.1 - 0.11 12.1 0.0 1.3 8.6 0.0 2.0 1 1 1 2 2 2 0 Beta-lactamase enzyme family CAP_GLY PF01302.25 KDO16075.1 - 5.6e-19 67.9 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain DnaJ PF00226.31 KDO16075.1 - 1.8e-16 60.0 0.3 2.8e-16 59.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DENN PF02141.21 KDO16077.1 - 4.8e-26 91.9 0.2 6.4e-26 91.4 0.2 1.1 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KDO16077.1 - 7.7e-08 33.0 0.5 1.5e-07 32.0 0.5 1.5 1 0 0 1 1 1 1 uDENN domain Pkinase PF00069.25 KDO16078.1 - 1.2e-44 152.7 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16078.1 - 1.9e-22 79.8 0.0 2.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO16078.1 - 8e-07 28.6 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO16078.1 - 2.1e-05 24.6 0.2 0.00078 19.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO16078.1 - 0.00032 19.7 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KDO16078.1 - 0.00041 20.0 0.1 0.00097 18.8 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KDO16078.1 - 0.0079 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Baculo_19 PF04798.12 KDO16078.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.8 2 1 1 3 3 3 0 Baculovirus 19 kDa protein conserved region Myosin_tail_1 PF01576.19 KDO16078.1 - 0.29 8.9 0.3 0.35 8.6 0.3 1.0 1 0 0 1 1 1 0 Myosin tail Glycohydro_20b2 PF14845.6 KDO16081.1 - 0.14 12.8 0.1 0.18 12.5 0.1 1.2 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like FlgD_ig PF13860.6 KDO16082.1 - 0.084 12.8 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain Lipase_3 PF01764.25 KDO16083.1 - 0.023 14.6 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) 7tm_7 PF08395.12 KDO16083.1 - 1 8.5 11.6 0.39 9.9 1.4 3.2 3 0 0 3 3 3 0 7tm Chemosensory receptor TauD PF02668.16 KDO16084.1 - 7.3e-38 130.9 0.0 1.3e-37 130.1 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KDO16084.1 - 4.7e-18 65.6 0.0 1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) HD PF01966.22 KDO16084.1 - 6.7e-05 23.1 0.8 0.00013 22.2 0.8 1.4 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KDO16084.1 - 0.014 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 HDOD domain HD_4 PF13328.6 KDO16084.1 - 0.019 14.7 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 HD domain CsiD PF08943.10 KDO16084.1 - 0.054 12.6 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 CsiD 2OG-FeII_Oxy_2 PF13532.6 KDO16086.1 - 7.2e-09 36.1 0.0 8.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 KDO16088.1 - 4e-27 95.5 0.1 5.2e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO16088.1 - 0.00051 20.7 1.9 0.00077 20.1 1.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ras PF00071.22 KDO16089.1 - 1.5e-10 40.9 0.1 1.7e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO16089.1 - 1.8e-08 34.7 0.0 2e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KDO16089.1 - 0.0019 18.2 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KDO16089.1 - 0.0054 16.4 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO16089.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 KDO16089.1 - 0.013 14.6 0.0 0.014 14.5 0.0 1.0 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KDO16089.1 - 0.032 13.7 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KDO16089.1 - 0.037 13.4 0.0 0.037 13.4 0.0 1.0 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KDO16089.1 - 0.038 14.4 0.0 0.038 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KDO16089.1 - 0.044 14.0 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KDO16089.1 - 0.063 12.4 0.0 0.063 12.4 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KDO16089.1 - 0.08 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO16089.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KDO16089.1 - 0.16 12.5 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 ABC transporter Glutaredoxin PF00462.24 KDO16090.1 - 2.3e-18 66.1 0.1 3.7e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KDO16090.1 - 0.00022 21.6 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KDO16090.1 - 0.0011 18.7 0.5 0.014 15.2 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain GST_N_2 PF13409.6 KDO16090.1 - 0.0046 17.2 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO16090.1 - 0.012 16.0 0.0 0.018 15.5 0.0 1.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 KDO16090.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KDO16090.1 - 0.039 14.4 0.2 0.051 14.0 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KDO16090.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin AAA PF00004.29 KDO16091.1 - 1.6e-07 31.8 0.0 3.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KDO16091.1 - 1.4e-06 28.3 0.5 0.014 15.3 0.0 2.4 1 1 1 2 2 2 2 NTPase AAA_16 PF13191.6 KDO16091.1 - 1.8e-06 28.5 0.0 3.1e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KDO16091.1 - 3.1e-06 26.8 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 KDO16091.1 - 2.6e-05 24.3 0.0 6.3e-05 23.0 0.0 1.6 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KDO16091.1 - 2.7e-05 24.2 0.0 9.5e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO16091.1 - 5.1e-05 23.1 0.0 0.00011 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO16091.1 - 0.00011 22.5 0.0 0.00032 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO16091.1 - 0.00021 21.8 0.0 0.00042 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO16091.1 - 0.00033 20.8 0.0 0.00067 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KDO16091.1 - 0.00039 19.9 0.2 0.0041 16.5 0.2 2.2 1 1 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 KDO16091.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KDO16091.1 - 0.0016 18.8 0.0 0.0054 17.1 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.18 KDO16091.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KDO16091.1 - 0.002 17.9 0.0 0.2 11.4 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KDO16091.1 - 0.0023 17.7 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KDO16091.1 - 0.0048 17.4 0.1 0.0077 16.7 0.1 1.6 1 1 0 1 1 1 1 ABC transporter MCM PF00493.23 KDO16091.1 - 0.0051 15.9 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 MCM P-loop domain Zeta_toxin PF06414.12 KDO16091.1 - 0.006 15.9 0.0 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 KDO16091.1 - 0.0062 15.6 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 KDO16091.1 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.11 KDO16091.1 - 0.0082 16.0 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KDO16091.1 - 0.0095 15.7 0.1 0.039 13.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 KDO16091.1 - 0.0096 15.1 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_28 PF13521.6 KDO16091.1 - 0.0097 16.2 0.0 0.022 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KDO16091.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KDO16091.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO16091.1 - 0.012 15.9 0.0 0.028 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO16091.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KDO16091.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 KDO16091.1 - 0.018 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CbiA PF01656.23 KDO16091.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 KDO16091.1 - 0.031 14.7 0.1 0.28 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KDO16091.1 - 0.032 14.3 0.0 0.049 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) KTI12 PF08433.10 KDO16091.1 - 0.033 13.6 0.1 0.19 11.2 0.0 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 ResIII PF04851.15 KDO16091.1 - 0.04 13.9 0.1 0.21 11.6 0.0 2.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 KDO16091.1 - 0.048 12.8 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.22 KDO16091.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase ATPase_2 PF01637.18 KDO16091.1 - 0.059 13.3 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KDO16091.1 - 0.061 13.1 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KDO16091.1 - 0.062 12.9 0.1 0.52 9.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KDO16091.1 - 0.065 12.6 0.1 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 KDO16091.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 KDO16091.1 - 0.1 12.2 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Translin PF01997.16 KDO16093.1 - 7.2e-05 22.9 0.0 7.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Translin family C2 PF00168.30 KDO16094.1 - 1.1e-15 57.8 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain Arrestin_N PF00339.29 KDO16096.1 - 7.3e-14 52.0 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KDO16096.1 - 3.6e-08 33.9 0.0 1.6e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain TMEM190 PF15431.6 KDO16096.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 Arrestin_C PF02752.22 KDO16097.1 - 8.1e-10 39.3 0.0 2.4e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ank_4 PF13637.6 KDO16098.1 - 9.8e-18 64.3 9.2 0.0015 19.0 0.1 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO16098.1 - 1.4e-16 60.9 4.0 1.6e-06 28.6 0.3 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO16098.1 - 7e-12 45.3 5.6 0.06 13.7 0.1 7.1 3 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16098.1 - 2e-07 30.8 1.5 53 4.9 0.0 8.1 9 0 0 9 9 9 0 Ankyrin repeat Ank PF00023.30 KDO16098.1 - 0.036 14.5 2.0 1.3e+02 3.3 0.0 5.4 4 2 0 4 4 4 0 Ankyrin repeat TctC PF03401.14 KDO16100.1 - 0.061 12.4 0.0 0.066 12.3 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor DUF3798 PF12683.7 KDO16100.1 - 0.25 10.8 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) E1-E2_ATPase PF00122.20 KDO16101.1 - 0.23 11.0 0.0 0.66 9.5 0.0 1.7 2 0 0 2 2 2 0 E1-E2 ATPase TrkA_TMD PF18613.1 KDO16101.1 - 0.41 10.1 3.3 1.1 8.8 3.3 1.6 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain FliE PF02049.18 KDO16103.1 - 0.084 13.0 0.8 0.12 12.5 0.8 1.2 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE GlcNAc PF11397.8 KDO16104.1 - 9.4e-18 64.8 0.1 1.5e-09 37.8 0.1 2.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) ORC6 PF05460.13 KDO16105.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Zip PF02535.22 KDO16106.1 - 7.9e-24 84.5 12.1 2.1e-17 63.4 5.9 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Mobilization_B PF17511.2 KDO16107.1 - 0.012 15.9 0.4 0.014 15.8 0.4 1.2 1 0 0 1 1 1 0 Mobilization protein B SlyX PF04102.12 KDO16107.1 - 0.36 11.5 4.9 1.4 9.6 0.1 2.5 2 1 0 2 2 2 0 SlyX p450 PF00067.22 KDO16108.1 - 4.1e-13 48.9 0.0 2.5e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Kelch_2 PF07646.15 KDO16108.1 - 0.098 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Kelch motif CH_2 PF06294.11 KDO16109.1 - 8.2e-36 122.0 1.0 3.5e-35 120.0 0.0 2.2 2 1 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KDO16109.1 - 1.7e-17 63.0 0.0 3.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 KDO16109.1 - 0.0023 18.1 0.3 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF641 PF04859.12 KDO16109.1 - 0.0039 17.5 3.4 0.0054 17.1 1.8 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) FAM196 PF15265.6 KDO16109.1 - 0.0064 16.1 0.6 0.0064 16.1 0.6 1.2 1 0 0 1 1 1 1 FAM196 family HrpB7 PF09486.10 KDO16109.1 - 0.012 16.1 1.4 0.018 15.4 1.4 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) UPF0242 PF06785.11 KDO16109.1 - 0.022 14.9 6.9 0.052 13.7 6.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 KDO16109.1 - 0.039 13.8 8.0 2.7 7.9 1.0 3.3 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase dTDP_sugar_isom PF00908.17 KDO16109.1 - 0.055 13.2 0.2 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase FAM76 PF16046.5 KDO16109.1 - 0.093 12.1 1.2 0.11 11.8 1.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF16 PF01519.16 KDO16109.1 - 0.12 12.8 4.5 0.079 13.4 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 BST2 PF16716.5 KDO16109.1 - 2.3 8.8 10.1 3.7 8.2 7.8 2.2 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 TRAF_BIRC3_bd PF16673.5 KDO16111.1 - 0.23 11.3 0.2 0.38 10.6 0.2 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Glyco_hydro_17 PF00332.18 KDO16112.1 - 0.0014 18.3 1.8 0.15 11.6 1.8 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Bindin PF02084.15 KDO16112.1 - 0.066 13.5 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Bindin Acyltransferase PF01553.21 KDO16113.1 - 5.7e-07 29.2 0.0 2.4e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase LSM PF01423.22 KDO16114.1 - 2.7e-14 52.6 0.1 3e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO16114.1 - 5.6e-05 23.2 0.0 6.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain UME PF08064.13 KDO16115.1 - 0.048 13.6 2.4 0.53 10.2 0.2 2.8 3 0 0 3 3 3 0 UME (NUC010) domain Ribosomal_L1 PF00687.21 KDO16116.1 - 2e-14 53.8 0.2 2.2e-14 53.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family EamA PF00892.20 KDO16117.1 - 5.1e-08 33.2 8.4 5.1e-08 33.2 8.4 3.4 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 KDO16117.1 - 1.1e-06 28.4 7.7 1.4e-06 28.0 7.2 1.5 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KDO16117.1 - 5.7e-06 25.8 5.2 5.7e-06 25.8 5.2 1.5 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KDO16117.1 - 0.041 13.2 9.1 0.071 12.5 9.1 1.4 1 0 0 1 1 1 0 Triose-phosphate Transporter family Nsp1_C PF05064.13 KDO16118.1 - 0.036 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region CorA PF01544.18 KDO16118.1 - 0.059 12.7 0.1 0.065 12.5 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0184 PF03670.13 KDO16118.1 - 0.14 12.6 0.5 0.2 12.1 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) ABC_tran PF00005.27 KDO16120.1 - 1.9e-10 41.4 0.0 3.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KDO16120.1 - 0.0011 18.5 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KDO16120.1 - 0.037 14.3 1.3 0.75 10.1 1.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit S1_2 PF13509.6 KDO16122.1 - 0.039 14.0 0.0 0.23 11.5 0.0 2.4 3 0 0 3 3 3 0 S1 domain SPG4 PF17325.2 KDO16122.1 - 1.6 9.8 4.7 0.98 10.5 0.2 2.3 2 0 0 2 2 2 0 Stationary phase protein 4 AP3D1 PF06375.11 KDO16122.1 - 2.3 8.4 11.7 0.67 10.2 1.6 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 tRNA-synt_1b PF00579.25 KDO16124.1 - 1.3e-09 37.8 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Arf PF00025.21 KDO16125.1 - 1.5e-51 174.4 0.0 2e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KDO16125.1 - 5.4e-13 48.8 0.0 6.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO16125.1 - 2.7e-12 46.9 0.0 3.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO16125.1 - 5.6e-08 32.4 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO16125.1 - 1.4e-07 31.0 0.2 0.00081 18.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO16125.1 - 1.8e-06 28.0 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO16125.1 - 0.0054 16.1 0.0 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 KDO16125.1 - 0.059 12.7 0.0 0.086 12.1 0.0 1.3 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_24 PF13479.6 KDO16125.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KDO16125.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain DHHC PF01529.20 KDO16126.1 - 1.7e-20 73.5 9.7 1.7e-20 73.5 9.7 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3440 PF11922.8 KDO16126.1 - 0.048 13.4 0.7 0.048 13.4 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Fer4_2 PF12797.7 KDO16126.1 - 0.82 9.9 7.6 0.31 11.2 1.2 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Aa_trans PF01490.18 KDO16127.1 - 6.4e-43 147.0 35.7 1.2e-41 142.8 35.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.24 KDO16128.1 - 7.8e-20 71.2 6.3 1.3e-19 70.4 6.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO16128.1 - 4.7e-11 42.2 5.7 5.4e-11 42.0 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KDO16128.1 - 0.0022 16.6 2.1 0.0026 16.4 2.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Rick_17kDa_Anti PF05433.15 KDO16128.1 - 0.032 14.1 3.6 0.032 14.1 3.6 2.1 2 1 0 2 2 2 0 Glycine zipper 2TM domain OATP PF03137.20 KDO16128.1 - 0.096 11.0 0.8 0.11 10.8 0.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3980 PF13140.6 KDO16128.1 - 0.12 12.8 2.5 2.8 8.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Aa_trans PF01490.18 KDO16132.1 - 2.2e-06 26.7 5.5 2.7e-06 26.4 5.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.22 KDO16134.1 - 9.8e-08 31.7 0.2 4.1e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3592 PF12158.8 KDO16136.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) HSF_DNA-bind PF00447.17 KDO16139.1 - 4.1e-25 88.2 1.7 7.9e-25 87.3 1.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding HA2 PF04408.23 KDO16140.1 - 5e-24 84.7 0.2 9e-24 83.8 0.2 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KDO16140.1 - 1.3e-20 73.6 0.0 4e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KDO16140.1 - 1.3e-10 41.5 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO16140.1 - 0.00031 20.5 0.2 0.0008 19.2 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KDO16140.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Malate_synthase PF01274.22 KDO16141.1 - 0.086 11.1 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Malate synthase Kinesin PF00225.23 KDO16143.1 - 3e-92 309.1 1.5 4.5e-92 308.5 1.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO16143.1 - 4.5e-18 65.6 0.0 2.7e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding RILP PF11461.8 KDO16143.1 - 0.15 12.3 1.7 0.54 10.5 1.7 2.0 1 0 0 1 1 1 0 Rab interacting lysosomal protein PKcGMP_CC PF16808.5 KDO16143.1 - 2.3 8.1 9.7 0.12 12.2 0.4 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Anoctamin PF04547.12 KDO16146.1 - 7.4e-18 64.6 4.3 9.7e-18 64.2 4.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel cNMP_binding PF00027.29 KDO16146.1 - 0.0033 17.5 0.0 0.0085 16.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Anoct_dimer PF16178.5 KDO16146.1 - 0.14 11.8 0.0 9.5 5.9 0.1 2.2 1 1 1 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Mg_trans_NIPA PF05653.14 KDO16148.1 - 1.1e-10 41.2 0.1 1.1e-10 41.1 0.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA Elongin_A PF06881.11 KDO16149.1 - 0.012 16.1 0.2 0.018 15.6 0.2 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MgtE_N PF03448.17 KDO16149.1 - 0.013 16.1 0.5 1.2 9.8 0.0 2.1 1 1 1 2 2 2 0 MgtE intracellular N domain ABC_membrane PF00664.23 KDO16150.1 - 9.4 5.8 12.1 0.69 9.5 2.8 3.0 1 1 2 3 3 3 0 ABC transporter transmembrane region Mg_trans_NIPA PF05653.14 KDO16151.1 - 3.2e-13 49.5 0.6 3.9e-13 49.2 0.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF3392 PF11872.8 KDO16151.1 - 0.0014 18.8 1.3 0.0021 18.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) Mg_trans_NIPA PF05653.14 KDO16152.1 - 4.4e-24 85.1 3.1 5.6e-24 84.8 3.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KDO16152.1 - 1.9e-08 34.5 1.3 1.9e-08 34.5 1.3 2.9 2 1 0 3 3 3 1 EamA-like transporter family DMT_6 PF04342.12 KDO16152.1 - 0.00062 19.9 3.4 0.014 15.6 0.7 2.3 2 0 0 2 2 2 1 Putative member of DMT superfamily (DUF486) DUF3382 PF11862.8 KDO16152.1 - 0.018 15.3 4.9 0.042 14.1 2.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3382) DUF2721 PF11026.8 KDO16152.1 - 0.22 11.4 4.7 7.8 6.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2304 PF10066.9 KDO16152.1 - 0.36 11.1 8.8 0.11 12.8 5.4 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) GAF PF01590.26 KDO16153.1 - 1e-06 29.4 0.1 2.3e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 KDO16153.1 - 0.00012 22.1 4.3 0.00026 21.0 4.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 KDO16153.1 - 0.00065 20.0 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain DUF1451 PF07295.11 KDO16153.1 - 0.79 9.8 3.6 1.2 9.2 3.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Arm_2 PF04826.13 KDO16155.1 - 1e-05 25.1 0.0 0.0012 18.3 0.1 2.7 2 1 1 3 3 3 2 Armadillo-like Arm PF00514.23 KDO16155.1 - 0.38 10.8 3.0 4.5 7.4 0.1 3.6 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat SPX PF03105.19 KDO16156.1 - 1.1e-16 61.7 16.5 8.9e-09 35.7 1.2 3.2 1 1 2 3 3 3 3 SPX domain CCDC154 PF15450.6 KDO16156.1 - 0.00024 19.8 0.7 0.00024 19.8 0.7 1.4 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 154 YPEB PF14620.6 KDO16156.1 - 0.00093 18.6 0.5 0.0013 18.2 0.5 1.2 1 0 0 1 1 1 1 YpeB sporulation TRCF PF03461.15 KDO16156.1 - 0.058 13.8 0.4 0.13 12.6 0.2 1.7 2 0 0 2 2 2 0 TRCF domain DUF4064 PF13273.6 KDO16157.1 - 0.057 13.7 0.8 0.13 12.6 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) TMEM132D_C PF15706.5 KDO16157.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Metallophos PF00149.28 KDO16160.1 - 2.8e-08 34.5 1.7 1.6e-07 32.1 1.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CBAH PF02275.18 KDO16161.1 - 4.3e-05 23.3 0.0 5.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family PP2C PF00481.21 KDO16164.1 - 1.7e-44 152.4 0.0 2.9e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 KDO16164.1 - 9.8e-06 25.1 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C_2 PF13672.6 KDO16164.1 - 2e-05 24.3 0.1 3.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO16164.1 - 0.021 14.8 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF2165 PF09933.9 KDO16165.1 - 0.097 12.7 0.0 0.097 12.7 0.0 1.5 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) Endonuclease_NS PF01223.23 KDO16166.1 - 3e-29 102.5 0.1 3.9e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KDO16166.1 - 0.018 15.2 0.4 0.052 13.7 0.4 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Erf4 PF10256.9 KDO16167.1 - 1.2e-05 25.4 0.0 1.6e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Cyt_bd_oxida_I PF01654.17 KDO16167.1 - 0.24 10.0 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Peptidase_M24 PF00557.24 KDO16168.1 - 6.8e-27 94.5 0.1 6.8e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 NTPase_I-T PF01931.18 KDO16169.1 - 1.7e-56 190.5 0.0 1.9e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF2476 PF10630.9 KDO16169.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) Ras PF00071.22 KDO16170.1 - 1.8e-30 105.7 0.0 3e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO16170.1 - 8.8e-24 84.0 0.0 1.8e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KDO16170.1 - 9.4e-09 35.4 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KDO16170.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO16170.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO16170.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO16170.1 - 0.024 14.5 0.0 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DCB PF16213.5 KDO16172.1 - 1.5e-10 41.0 0.2 2.3e-10 40.5 0.2 1.3 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 COG7 PF10191.9 KDO16173.1 - 2.2e-05 22.9 0.2 4e-05 22.1 0.0 1.6 2 1 0 2 2 2 1 Golgi complex component 7 (COG7) RINT1_TIP1 PF04437.13 KDO16173.1 - 0.00055 19.0 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Sec6 PF06046.13 KDO16173.1 - 0.0049 15.3 0.0 0.0099 14.3 0.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KDO16173.1 - 0.01 14.9 0.1 0.022 13.7 0.0 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal VPS53_C PF16854.5 KDO16173.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Porin_3 PF01459.22 KDO16174.1 - 3.4e-25 89.0 0.2 3.8e-25 88.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin FNIP PF05725.12 KDO16178.1 - 0.01 16.0 1.5 0.6 10.3 0.4 2.6 2 0 0 2 2 2 0 FNIP Repeat TB2_DP1_HVA22 PF03134.19 KDO16179.1 - 0.01 15.8 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family B2-adapt-app_C PF09066.10 KDO16180.1 - 6e-05 23.1 0.0 0.0002 21.4 0.0 1.9 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain OrsD PF12013.8 KDO16181.1 - 2.6e-06 27.8 0.7 2.6e-06 27.8 0.7 1.8 2 1 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D Aa_trans PF01490.18 KDO16182.1 - 2.9e-11 42.7 1.1 3.4e-11 42.5 1.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_4 PF18186.1 KDO16182.1 - 0.055 13.1 1.5 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Bac_export_2 PF01312.19 KDO16182.1 - 0.069 12.4 1.1 1.1 8.5 0.2 2.1 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family PKD_channel PF08016.12 KDO16182.1 - 0.08 11.6 2.0 0.11 11.2 2.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel Ank_2 PF12796.7 KDO16183.1 - 3.3e-37 126.9 5.9 6.3e-11 42.7 0.5 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KDO16183.1 - 6e-30 102.4 17.8 0.00031 21.0 0.1 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KDO16183.1 - 8.5e-30 102.7 15.3 1.2e-09 38.5 0.0 8.0 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16183.1 - 2.5e-29 98.0 12.8 0.019 15.5 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KDO16183.1 - 2.9e-26 91.2 11.6 5e-06 26.7 0.0 7.8 4 3 4 8 8 8 7 Ankyrin repeats (many copies) BTB PF00651.31 KDO16183.1 - 3.9e-14 52.8 0.0 2.1e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain FYVE PF01363.21 KDO16183.1 - 1.6e-12 47.3 4.9 3.3e-12 46.4 4.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger zf-H2C2 PF09337.10 KDO16184.1 - 0.043 14.0 0.2 0.091 13.0 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase PF00069.25 KDO16186.1 - 8.2e-15 54.9 0.0 8.9e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16186.1 - 1.4e-12 47.5 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 KDO16187.1 - 1.8e-18 66.6 27.0 3.6e-14 52.5 7.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KDO16187.1 - 7.8e-05 21.7 8.0 7.8e-05 21.7 8.0 1.5 1 1 1 2 2 2 1 MFS_1 like family IQ PF00612.27 KDO16188.1 - 1.3e-05 24.6 25.6 0.0016 18.1 0.3 3.9 4 0 0 4 4 4 3 IQ calmodulin-binding motif Fibin PF15819.5 KDO16188.1 - 0.068 12.9 3.7 0.097 12.4 2.7 1.8 1 1 0 1 1 1 0 Fin bud initiation factor homologue Allexi_40kDa PF05549.11 KDO16188.1 - 1.5 8.3 10.2 0.4 10.2 1.9 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein HAGH_C PF16123.5 KDO16188.1 - 2.9 8.5 7.0 1.7 9.2 0.2 3.1 2 2 1 3 3 3 0 Hydroxyacylglutathione hydrolase C-terminus UPF0242 PF06785.11 KDO16188.1 - 5.2 7.1 24.1 0.057 13.5 5.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GDPD PF03009.17 KDO16189.1 - 7.2e-09 35.7 0.0 8.2e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Gemin6 PF06372.12 KDO16191.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Gemin6 protein Fip1 PF05182.13 KDO16192.1 - 0.027 14.0 0.5 0.052 13.1 0.5 1.4 1 0 0 1 1 1 0 Fip1 motif Ricin_B_lectin PF00652.22 KDO16193.1 - 8.6e-14 51.9 0.4 1e-13 51.7 0.4 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KDO16193.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Peptidase_C1 PF00112.23 KDO16194.1 - 3.7e-56 190.7 0.6 5.4e-56 190.1 0.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Ricin_B_lectin PF00652.22 KDO16194.1 - 0.0089 16.3 2.4 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain LCE PF14672.6 KDO16194.1 - 0.16 12.6 6.5 0.45 11.2 6.5 1.8 1 0 0 1 1 1 0 Late cornified envelope Ribonuc_red_sm PF00268.21 KDO16195.1 - 2.3e-32 112.6 0.0 2.8e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PX PF00787.24 KDO16196.1 - 1.2e-08 34.9 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF4375 PF14300.6 KDO16197.1 - 0.04 14.2 0.4 0.043 14.1 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) GvpL_GvpF PF06386.11 KDO16197.1 - 0.23 11.3 5.2 0.25 11.2 5.2 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Sigma70_r1_1 PF03979.14 KDO16199.1 - 0.026 14.6 0.1 0.93 9.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 RTTN_N PF14726.6 KDO16201.1 - 0.021 15.6 0.0 0.038 14.8 0.0 1.5 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning TonB_C PF03544.14 KDO16201.1 - 0.22 12.0 0.5 5.5 7.5 0.1 2.5 3 0 0 3 3 3 0 Gram-negative bacterial TonB protein C-terminal Metallophos PF00149.28 KDO16202.1 - 1.8e-32 113.5 0.0 4e-32 112.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cu-oxidase_2 PF07731.14 KDO16202.1 - 2.8e-12 46.6 0.2 5.2e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Multicopper oxidase FYVE PF01363.21 KDO16203.1 - 2.5e-14 53.2 13.8 4.7e-14 52.3 13.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO16203.1 - 0.00023 21.4 3.8 0.00046 20.4 3.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 KDO16203.1 - 0.26 11.5 6.8 0.7 10.2 6.8 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KDO16203.1 - 0.39 11.1 12.2 1.1 9.7 12.2 1.8 1 0 0 1 1 1 0 Ring finger domain GPR15L PF15854.5 KDO16203.1 - 5.2 7.4 12.5 5.3 7.3 1.7 2.4 1 1 1 2 2 2 0 G-protein coupled receptor ligand 15 Kinesin PF00225.23 KDO16205.1 - 2e-98 329.4 0.0 3.3e-98 328.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO16205.1 - 1.7e-24 86.4 0.0 3.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF4140 PF13600.6 KDO16205.1 - 0.11 13.0 12.4 2.2 8.7 4.3 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) PHD PF00628.29 KDO16205.1 - 0.22 11.5 13.5 0.03 14.2 9.3 1.8 2 0 0 2 2 2 0 PHD-finger DUF4407 PF14362.6 KDO16205.1 - 0.87 8.9 9.8 2.3 7.5 9.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 KDO16205.1 - 1.2 9.4 7.0 4.8 7.6 2.4 2.6 1 1 1 2 2 2 0 Tup N-terminal FlxA PF14282.6 KDO16205.1 - 1.5 8.9 13.3 1.3 9.0 4.3 2.9 3 0 0 3 3 3 0 FlxA-like protein Golgin_A5 PF09787.9 KDO16205.1 - 2 7.8 15.0 0.082 12.4 5.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 SlyX PF04102.12 KDO16205.1 - 3.2 8.5 13.3 2.2 9.0 3.4 4.1 3 1 1 4 4 4 0 SlyX Pkinase PF00069.25 KDO16207.1 - 3.8e-72 242.8 0.0 4.8e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16207.1 - 5e-44 150.5 0.0 6.4e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO16207.1 - 1.6e-07 31.0 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO16207.1 - 0.00012 21.5 1.4 0.00021 20.7 1.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO16207.1 - 0.0036 16.9 0.8 0.0068 16.0 0.8 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO16207.1 - 0.018 15.0 0.3 0.17 11.8 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Yippee-Mis18 PF03226.14 KDO16208.1 - 1.1e-10 41.7 0.3 1.5e-10 41.3 0.3 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Sec23_Sec24 PF04810.15 KDO16208.1 - 3.1 7.9 7.8 5.1 7.2 0.9 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Ras PF00071.22 KDO16210.1 - 2.8e-55 186.4 0.1 3.2e-55 186.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO16210.1 - 1.6e-20 73.5 0.1 2.2e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO16210.1 - 2.4e-10 40.2 0.1 2.8e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KDO16210.1 - 1.4e-06 28.4 0.1 0.024 14.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO16210.1 - 0.00033 20.3 0.2 0.0017 18.0 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO16210.1 - 0.00096 19.2 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KDO16210.1 - 0.03 13.6 0.1 0.14 11.4 0.0 2.0 3 0 0 3 3 3 0 Septin G-alpha PF00503.20 KDO16210.1 - 0.051 12.7 0.2 5.5 6.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 KDO16210.1 - 0.058 12.8 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KDO16210.1 - 0.073 13.5 0.1 0.086 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KDO16210.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain HAP1_N PF04849.13 KDO16211.1 - 1.1e-05 24.9 4.0 1.6e-05 24.3 4.0 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region MCM_bind PF09739.9 KDO16212.1 - 1.5e-29 102.9 0.0 1.6e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor DUF1479 PF07350.12 KDO16212.1 - 0.091 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Robl_LC7 PF03259.17 KDO16213.1 - 1.5e-20 72.8 0.0 1.6e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KDO16213.1 - 0.00019 21.3 0.0 0.00021 21.1 0.0 1.3 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 CHASE8 PF17152.4 KDO16213.1 - 0.024 14.9 0.0 0.036 14.3 0.0 1.3 1 1 0 1 1 1 0 Periplasmic sensor domain V-ATPase_H_C PF11698.8 KDO16214.1 - 0.00024 21.2 0.1 0.98 9.5 0.0 2.8 2 2 1 3 3 3 2 V-ATPase subunit H HEAT PF02985.22 KDO16214.1 - 0.00032 20.7 0.5 5.3 7.6 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KDO16214.1 - 0.00061 20.1 2.6 0.0021 18.4 0.2 2.5 2 1 0 2 2 2 1 HEAT repeats Arm_2 PF04826.13 KDO16214.1 - 0.0028 17.2 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 KDO16214.1 - 0.0061 16.6 0.2 1.9 8.7 0.0 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KDO16214.1 - 0.016 13.8 0.4 1.1 7.7 0.1 2.1 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 KDO16214.1 - 0.022 14.8 2.7 1.5 8.9 0.5 2.5 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO16214.1 - 0.052 14.1 0.2 0.67 10.5 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat WW PF00397.26 KDO16215.1 - 1.3e-21 76.3 7.0 2.9e-10 40.0 1.1 2.7 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KDO16215.1 - 5.8e-05 23.4 6.5 0.038 14.3 2.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 KDO16215.1 - 0.0015 18.4 0.8 0.24 11.4 0.1 2.4 2 0 0 2 2 2 2 PQQ enzyme repeat WD40_3 PF15911.5 KDO16215.1 - 0.0025 17.8 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Pkinase PF00069.25 KDO16216.1 - 5.8e-16 58.6 0.0 7.3e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16216.1 - 2.5e-15 56.5 0.0 3.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TraB PF01963.17 KDO16216.1 - 0.14 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 TraB family FYVE PF01363.21 KDO16218.1 - 1.8e-12 47.2 12.3 2.2e-12 46.9 12.3 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO16218.1 - 0.83 9.9 10.2 2.2 8.5 10.3 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Lipase_3 PF01764.25 KDO16219.1 - 4.2e-17 62.3 0.0 7.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 KDO16219.1 - 1.4e-05 25.1 7.4 2.8e-05 24.2 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger Abhydrolase_3 PF07859.13 KDO16219.1 - 0.0046 16.8 2.9 0.009 15.9 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2048 PF09752.9 KDO16219.1 - 0.015 14.4 0.2 0.024 13.7 0.2 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Hydrolase_4 PF12146.8 KDO16219.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KDO16219.1 - 0.084 11.8 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KDO16219.1 - 0.098 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold FYVE_2 PF02318.16 KDO16219.1 - 0.59 10.4 3.0 40 4.4 2.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Pyr_redox_2 PF07992.14 KDO16220.1 - 0.065 12.5 0.0 0.23 10.6 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Longin PF13774.6 KDO16222.1 - 0.00053 20.0 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF4884 PF16225.5 KDO16222.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Arm PF00514.23 KDO16224.1 - 0.017 15.1 0.1 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 KDO16226.1 - 1.5e-08 35.1 9.6 0.0013 19.2 0.8 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16226.1 - 1.8e-08 34.7 12.9 0.0022 18.5 0.2 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16226.1 - 0.00014 22.1 11.2 0.76 10.2 0.1 5.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16226.1 - 0.0075 16.7 9.2 1.6 9.6 0.0 5.5 7 0 0 7 7 7 1 Ankyrin repeat Abhydrolase_1 PF00561.20 KDO16228.1 - 1.6e-18 67.3 0.1 1.4e-17 64.2 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO16228.1 - 9.5e-18 64.2 0.0 2.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KDO16228.1 - 0.00089 18.6 0.0 0.81 8.9 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 ECH_1 PF00378.20 KDO16230.1 - 2.7e-50 171.0 0.1 1.6e-49 168.5 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO16230.1 - 2.7e-28 99.5 0.4 1.1e-25 90.8 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_6 PF01341.17 KDO16232.1 - 3.3e-25 89.5 0.1 4.1e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 TIP49_C PF17856.1 KDO16232.1 - 0.14 12.3 0.2 0.29 11.3 0.0 1.5 2 0 0 2 2 2 0 TIP49 AAA-lid domain DUF3336 PF11815.8 KDO16233.1 - 1.9e-27 95.7 0.0 5.3e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KDO16233.1 - 1e-20 74.8 0.1 1.6e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3821 PF12863.7 KDO16233.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) HrpB1_HrpK PF09613.10 KDO16235.1 - 0.0075 15.9 0.4 0.0087 15.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) FlgN PF05130.12 KDO16235.1 - 0.017 15.6 0.9 0.022 15.3 0.9 1.1 1 0 0 1 1 1 0 FlgN protein Lactamase_B_2 PF12706.7 KDO16236.1 - 4.1e-34 117.9 0.1 4.9e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KDO16236.1 - 2.3e-06 27.6 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO16236.1 - 0.004 17.2 1.0 0.034 14.1 0.3 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO16237.1 - 1.7e-10 40.8 0.2 1.3e-06 28.1 0.4 2.3 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KDO16237.1 - 7.6e-08 32.4 0.0 9.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO16237.1 - 0.031 14.3 0.2 0.06 13.3 0.2 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lar_restr_allev PF14354.6 KDO16239.1 - 0.029 14.7 0.6 0.051 14.0 0.6 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar F-box PF00646.33 KDO16241.1 - 3.9e-08 33.0 0.6 3.9e-08 33.0 0.6 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KDO16241.1 - 2.6e-05 24.0 0.5 6.4e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 F-box-like Arf PF00025.21 KDO16242.1 - 1.1e-12 47.8 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arf PF00025.21 KDO16243.1 - 2.4e-67 225.8 0.0 2.8e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO16243.1 - 4.2e-15 56.0 0.1 5.7e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO16243.1 - 1.6e-12 47.3 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KDO16243.1 - 5.1e-12 45.6 0.0 6.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO16243.1 - 2.3e-11 43.4 1.1 1.7e-08 34.0 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KDO16243.1 - 3.8e-09 36.3 0.0 4.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO16243.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO16243.1 - 0.0038 16.8 0.1 0.018 14.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.18 KDO16243.1 - 0.012 14.9 0.1 0.018 14.3 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AA_permease_2 PF13520.6 KDO16245.1 - 6e-35 120.9 37.4 2.6e-34 118.8 37.4 1.8 1 1 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 KDO16246.1 - 1.7e-19 70.2 18.3 4.6e-05 23.9 0.1 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16246.1 - 3.6e-15 56.1 13.8 0.0098 16.5 0.0 6.7 6 2 0 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16246.1 - 1.8e-12 47.3 19.0 0.075 13.4 0.0 9.1 4 3 6 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16246.1 - 4.2e-09 35.9 7.9 32 5.6 0.0 8.7 10 0 0 10 10 10 0 Ankyrin repeat Ank PF00023.30 KDO16246.1 - 0.0032 17.8 6.9 52 4.5 0.9 6.4 4 2 1 5 5 5 0 Ankyrin repeat DUF5049 PF16468.5 KDO16246.1 - 0.0035 17.2 2.2 8.6 6.3 0.0 5.3 4 2 3 7 7 7 1 Domain of unknown function (DUF5049) DUF3447 PF11929.8 KDO16246.1 - 0.0054 16.7 0.0 0.53 10.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) SURNod19 PF07712.12 KDO16248.1 - 2e-13 49.9 0.1 4e-13 48.9 0.1 1.4 1 1 0 1 1 1 1 Stress up-regulated Nod 19 Rtt106 PF08512.12 KDO16249.1 - 1.3e-24 86.4 0.0 1.8e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Histone chaperone Rttp106-like YL1 PF05764.13 KDO16249.1 - 0.15 12.2 25.9 0.18 11.9 25.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.11 KDO16249.1 - 0.3 10.6 14.8 0.34 10.5 14.8 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KDO16249.1 - 0.85 7.8 21.9 1 7.5 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 KDO16249.1 - 7.6 5.4 17.9 10 5.0 17.9 1.2 1 0 0 1 1 1 0 Paf1 Ctr PF04145.15 KDO16250.1 - 5.5e-15 56.3 14.5 7.9e-10 39.5 9.5 2.2 1 1 1 2 2 2 2 Ctr copper transporter family HMA PF00403.26 KDO16250.1 - 5.2e-05 23.6 0.1 7.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain MTES_1575 PF18741.1 KDO16251.1 - 0.028 14.6 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 REase_MTES_1575 AA_kinase PF00696.28 KDO16252.1 - 0.00027 20.6 0.2 0.00032 20.4 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family BTB_2 PF02214.22 KDO16254.1 - 0.0001 22.6 0.0 0.00031 21.1 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain CheB_methylest PF01339.17 KDO16254.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 CheB methylesterase Peptidase_M32 PF02074.15 KDO16254.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase NUDE_C PF04880.13 KDO16255.1 - 0.26 11.8 5.4 0.28 11.6 5.4 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Utp12 PF04003.12 KDO16258.1 - 0.0011 19.3 0.4 0.0038 17.5 0.4 2.0 1 0 0 1 1 1 1 Dip2/Utp12 Family FYVE PF01363.21 KDO16259.1 - 6.8e-14 51.8 18.0 1.3e-13 50.9 18.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO16259.1 - 3.5e-08 34.1 0.2 1.2e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KDO16259.1 - 2.8e-05 24.4 0.1 6.6e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO16259.1 - 0.12 12.5 9.6 0.25 11.6 9.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Ank_2 PF12796.7 KDO16261.1 - 5.7e-08 33.2 0.4 0.00016 22.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16261.1 - 1.8e-07 31.6 2.1 0.0082 16.7 0.0 4.3 3 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16261.1 - 0.00082 19.6 2.8 7.4 7.5 0.0 5.9 6 1 1 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KDO16261.1 - 0.11 12.8 1.9 49 4.4 0.0 4.5 2 1 2 5 5 5 0 Ankyrin repeats (many copies) DUF1116 PF06545.11 KDO16262.1 - 0.0048 16.4 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) PH_9 PF15410.6 KDO16262.1 - 0.057 13.8 0.7 0.51 10.7 0.1 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain COG4 PF08318.12 KDO16263.1 - 2.5e-32 112.3 0.0 3.7e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 KDO16263.1 - 0.00041 19.4 0.0 0.00078 18.5 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Ion_trans PF00520.31 KDO16264.1 - 9.3e-20 70.9 11.8 1.7e-19 70.1 11.8 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO16264.1 - 6.4e-12 45.3 0.8 6.4e-12 45.3 0.8 2.4 3 1 0 3 3 3 1 Ion channel WD40 PF00400.32 KDO16265.1 - 1.6e-27 95.2 8.7 9.6e-08 32.6 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO16265.1 - 3.7e-10 40.0 0.5 7.5e-05 23.0 0.1 4.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO16265.1 - 7.2e-08 32.5 0.3 0.034 14.0 0.0 3.4 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KDO16265.1 - 0.0044 17.0 0.0 0.023 14.7 0.0 2.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KDO16265.1 - 0.0075 15.1 0.6 2 7.1 0.0 3.0 1 1 2 3 3 3 2 Nup133 N terminal like AAA_18 PF13238.6 KDO16266.1 - 5.8e-05 23.7 0.5 0.00028 21.4 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KDO16266.1 - 0.00063 19.9 1.8 0.0045 17.2 1.8 2.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KDO16266.1 - 0.0012 18.2 0.0 0.0036 16.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KDO16266.1 - 0.0015 18.5 0.3 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KDO16266.1 - 0.0055 17.1 0.2 0.032 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KDO16266.1 - 0.0089 16.3 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO16266.1 - 0.0089 15.6 0.0 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KDO16266.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KDO16266.1 - 0.018 15.5 0.3 0.073 13.6 0.3 2.1 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KDO16266.1 - 0.023 14.7 2.3 0.092 12.7 0.8 2.6 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KDO16266.1 - 0.024 15.1 0.1 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KDO16266.1 - 0.027 14.2 0.5 0.066 12.9 0.5 1.8 1 1 0 1 1 1 0 Cytidylate kinase SKI PF01202.22 KDO16266.1 - 0.033 14.3 0.4 4.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 KDO16266.1 - 0.048 13.4 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 KDO16266.1 - 0.065 13.3 1.1 0.16 12.0 1.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 KDO16266.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KDO16266.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DOT1 PF08123.13 KDO16268.1 - 3.7e-11 42.9 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 KDO16268.1 - 0.037 13.5 0.0 0.091 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_31 PF13847.6 KDO16268.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.7 KDO16269.1 - 0.0019 18.9 5.5 0.0031 18.2 5.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KDO16269.1 - 0.017 15.0 0.3 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 Lipase (class 3) LCAT PF02450.15 KDO16269.1 - 0.089 11.9 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase AAA_16 PF13191.6 KDO16269.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF3948 PF13134.6 KDO16270.1 - 0.098 12.4 0.2 0.32 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) C2 PF00168.30 KDO16271.1 - 2e-07 31.2 0.0 2.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain AMP-binding PF00501.28 KDO16272.1 - 5.3e-71 239.4 0.0 6.5e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF751 PF05421.11 KDO16273.1 - 0.015 16.0 0.5 0.024 15.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF751) RIFIN PF02009.16 KDO16273.1 - 0.035 14.0 0.8 0.039 13.9 0.8 1.1 1 0 0 1 1 1 0 Rifin Adeno_E3_CR2 PF02439.15 KDO16273.1 - 0.12 12.2 1.4 0.2 11.4 1.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4366 PF14283.6 KDO16273.1 - 0.12 12.4 3.6 0.19 11.7 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Carn_acyltransf PF00755.20 KDO16274.1 - 6.5e-07 28.4 2.2 7.4e-07 28.2 2.2 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase PF00069.25 KDO16275.1 - 0.0036 16.7 0.0 0.0036 16.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16275.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3697 PF12478.8 KDO16275.1 - 0.044 13.9 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 YlbD_coat PF14071.6 KDO16276.1 - 0.0054 17.0 1.7 0.0054 17.0 1.7 1.6 2 0 0 2 2 2 1 Putative coat protein DUF4476 PF14771.6 KDO16279.1 - 0.0011 19.2 0.0 0.029 14.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) AbbA_antirepres PF14156.6 KDO16279.1 - 0.19 11.6 0.0 0.51 10.3 0.0 1.7 1 0 0 1 1 1 0 Antirepressor AbbA Glyco_hydro_28 PF00295.17 KDO16280.1 - 0.00013 21.1 0.3 0.00014 21.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ricin_B_lectin PF00652.22 KDO16286.1 - 7.5e-06 26.2 0.0 1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain COQ9 PF08511.11 KDO16286.1 - 0.063 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 COQ9 Nitr_red_alph_N PF14710.6 KDO16286.1 - 0.11 13.0 1.4 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal Mito_carr PF00153.27 KDO16287.1 - 6e-36 122.3 0.3 4.1e-22 77.9 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Metallophos PF00149.28 KDO16288.1 - 6.7e-15 56.1 2.5 8.8e-15 55.8 2.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO16288.1 - 0.0036 17.5 0.0 0.0036 17.5 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Myosin_tail_1 PF01576.19 KDO16290.1 - 0.0046 14.8 0.2 0.005 14.7 0.2 1.0 1 0 0 1 1 1 1 Myosin tail LRR_6 PF13516.6 KDO16291.1 - 2.6e-10 39.5 11.6 0.00013 21.7 0.3 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 KDO16291.1 - 1.1e-06 28.2 6.1 0.067 13.0 0.1 4.4 3 2 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KDO16291.1 - 2.6e-05 24.1 4.7 19 6.3 0.1 5.4 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 KDO16291.1 - 0.0016 18.8 5.0 4.6 7.8 0.1 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) IQ PF00612.27 KDO16292.1 - 2.3e-07 30.0 28.0 0.02 14.6 0.7 5.8 4 1 0 4 4 4 4 IQ calmodulin-binding motif Gasdermin_C PF17708.1 KDO16292.1 - 0.042 13.9 1.3 0.14 12.3 1.3 1.8 1 0 0 1 1 1 0 Gasdermin PUB domain GRDP-like PF07173.12 KDO16293.1 - 4e-08 34.0 0.1 8.4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like DZR PF12773.7 KDO16293.1 - 0.041 13.9 2.4 0.43 10.6 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-FLZ PF04570.14 KDO16293.1 - 1 8.9 3.0 1.9 8.0 1.0 2.4 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 Zn_ribbon_recom PF13408.6 KDO16293.1 - 1.7 9.2 6.4 6.1 7.4 0.2 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain MAS20 PF02064.15 KDO16294.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Cation_ATPase_N PF00690.26 KDO16295.1 - 1.2e-14 53.7 0.0 1.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2431 PF10354.9 KDO16296.1 - 1.4e-09 38.5 0.0 1.7e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ROKNT PF08067.11 KDO16298.1 - 0.14 12.5 1.9 2.2 8.6 0.3 2.1 1 1 1 2 2 2 0 ROKNT (NUC014) domain Gal_Lectin PF02140.18 KDO16299.1 - 9.6e-86 282.3 23.6 4.4e-17 62.3 0.1 5.1 5 0 0 5 5 5 5 Galactose binding lectin domain DUF3395 PF11875.8 KDO16299.1 - 0.11 12.4 0.0 29 4.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3395) DUF1970 PF09301.10 KDO16299.1 - 0.64 10.3 10.0 7.9 6.8 0.6 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) EGF_2 PF07974.13 KDO16300.1 - 0.00035 20.9 46.0 0.011 16.0 14.0 5.1 4 1 0 4 4 4 3 EGF-like domain EGF PF00008.27 KDO16300.1 - 0.0028 17.9 36.9 0.0033 17.7 8.6 4.6 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KDO16300.1 - 0.021 15.5 36.5 0.025 15.2 6.7 5.9 5 1 0 5 5 5 0 Human growth factor-like EGF DUF2773 PF10971.8 KDO16300.1 - 0.03 14.5 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) PQQ_3 PF13570.6 KDO16300.1 - 0.25 11.9 1.2 1.3 9.6 0.2 2.8 2 0 0 2 2 2 0 PQQ-like domain ABC_tran PF00005.27 KDO16301.1 - 5.4e-28 98.2 0.0 1.1e-27 97.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO16301.1 - 3.3e-11 43.5 2.3 1e-08 35.4 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KDO16301.1 - 6.1e-08 32.2 7.0 8.6e-08 31.7 7.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 KDO16301.1 - 0.0014 19.0 0.1 0.003 18.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KDO16301.1 - 0.0019 17.6 0.2 0.11 11.9 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 KDO16301.1 - 0.019 15.7 0.1 2.1 9.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KDO16301.1 - 0.11 12.1 0.7 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KDO16301.1 - 0.17 11.8 0.0 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain EAP30 PF04157.16 KDO16302.1 - 3.5e-28 98.5 0.0 3.9e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family HTH_24 PF13412.6 KDO16302.1 - 0.045 13.3 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KDO16302.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain LRR_8 PF13855.6 KDO16303.1 - 1.8e-06 27.6 5.4 0.00097 18.9 2.6 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO16303.1 - 5.5e-05 23.5 1.5 5.5e-05 23.5 1.5 2.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Peptidase_M48 PF01435.18 KDO16304.1 - 4.2e-37 127.8 0.0 7.4e-37 127.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 Ank_4 PF13637.6 KDO16305.1 - 2.4e-29 101.3 6.0 8.8e-14 51.7 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO16305.1 - 1.3e-27 96.2 3.2 1.3e-17 64.1 1.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO16305.1 - 5.6e-25 86.7 12.9 1.4e-07 31.7 0.3 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KDO16305.1 - 2.2e-23 79.8 4.2 3.5e-05 23.9 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KDO16305.1 - 6e-18 64.7 7.4 7.2e-09 35.8 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF3037 PF11236.8 KDO16307.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Euplotes_phero PF05842.11 KDO16310.1 - 0.25 11.9 4.6 0.4 11.3 4.6 1.3 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Ank_4 PF13637.6 KDO16312.1 - 2.1e-15 56.9 14.3 4.9e-05 23.8 0.4 5.3 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO16312.1 - 6.5e-14 52.3 12.2 7.6e-07 29.6 1.9 3.7 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO16312.1 - 3.1e-08 33.2 8.5 1.5 9.6 0.2 7.4 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KDO16312.1 - 2.1e-05 24.7 12.9 1.8 9.0 0.2 6.3 3 1 4 7 7 7 3 Ankyrin repeats (many copies) CDO_I PF05995.12 KDO16312.1 - 7.9 5.8 8.9 1.5 8.1 0.4 3.0 3 0 0 3 3 3 0 Cysteine dioxygenase type I PIG-L PF02585.17 KDO16313.1 - 1.8e-10 41.5 0.2 4.1e-10 40.4 0.2 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_3 PF08277.12 KDO16313.1 - 0.02 14.7 0.3 0.046 13.5 0.3 1.5 1 0 0 1 1 1 0 PAN-like domain DGOK PF05035.12 KDO16313.1 - 0.051 12.5 0.1 0.081 11.8 0.1 1.3 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase TM231 PF10149.9 KDO16314.1 - 1.1e-45 156.3 0.0 1.2e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 ELMO_CED12 PF04727.13 KDO16315.1 - 7e-29 101.2 0.0 1.5e-28 100.1 0.0 1.5 1 1 0 1 1 1 1 ELMO/CED-12 family VbhA PF18495.1 KDO16315.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Antitoxin VbhA ENTH PF01417.20 KDO16316.1 - 0.0088 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KDO16316.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 ANTH domain MF_alpha_N PF05436.11 KDO16317.1 - 0.088 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus TPR_12 PF13424.6 KDO16318.1 - 1.4e-15 57.3 18.1 6.4e-06 26.4 3.6 3.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO16318.1 - 1.5e-15 56.2 5.5 0.00019 21.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16318.1 - 3.3e-13 48.6 9.1 0.0041 17.1 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KDO16318.1 - 4.7e-13 48.2 10.9 0.001 18.9 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO16318.1 - 9.8e-09 34.8 4.1 0.061 13.6 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO16318.1 - 5.6e-07 29.2 11.3 0.0021 17.8 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO16318.1 - 0.00027 20.4 11.6 0.038 13.4 6.2 2.2 2 0 0 2 2 2 2 MalT-like TPR region MIT PF04212.18 KDO16318.1 - 0.00085 19.3 2.6 0.051 13.7 0.5 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KDO16318.1 - 0.0017 19.0 13.1 0.39 11.7 0.0 4.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO16318.1 - 0.0074 16.8 7.4 0.16 12.7 0.2 3.6 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16318.1 - 0.014 16.0 16.7 2.7 8.7 2.4 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KDO16318.1 - 0.033 13.4 2.9 0.25 10.5 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO16318.1 - 0.05 13.3 2.4 5.6 6.7 0.1 4.0 4 1 1 5 5 5 0 TPR repeat TPR_17 PF13431.6 KDO16318.1 - 0.084 13.3 4.2 36 5.1 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO16318.1 - 1.2 9.3 11.5 1.2 9.3 2.7 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat 14-3-3 PF00244.20 KDO16319.1 - 1.3e-60 204.7 0.0 1.5e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein HNF-1A_C PF04813.12 KDO16321.1 - 0.071 13.9 2.2 0.15 12.9 2.2 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Aa_trans PF01490.18 KDO16322.1 - 1.4e-06 27.3 1.3 1.5e-06 27.2 1.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO16322.1 - 4.8e-05 22.6 1.4 5.2e-05 22.5 1.4 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF919 PF06034.11 KDO16324.1 - 0.005 16.7 0.4 0.0088 15.9 0.4 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) HrpB1_HrpK PF09613.10 KDO16326.1 - 0.039 13.6 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) OHCU_decarbox PF09349.10 KDO16326.1 - 0.18 12.3 0.7 0.52 10.8 0.3 1.8 2 0 0 2 2 2 0 OHCU decarboxylase VirD1 PF07328.11 KDO16327.1 - 0.0032 17.5 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 T-DNA border endonuclease VirD1 Ank_3 PF13606.6 KDO16328.1 - 0.0003 21.0 0.0 0.00078 19.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 KDO16328.1 - 0.00064 20.2 0.5 0.16 12.6 0.1 2.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16328.1 - 0.0031 17.8 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO16328.1 - 0.0033 18.0 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO16328.1 - 0.0069 16.8 0.1 0.014 15.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat DUF2924 PF11149.8 KDO16328.1 - 0.044 14.2 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) DUF347 PF03988.12 KDO16329.1 - 0.11 12.7 0.9 0.19 11.9 0.9 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DRMBL PF07522.14 KDO16331.1 - 2.9e-29 101.5 0.1 4e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Ank_4 PF13637.6 KDO16332.1 - 0.012 16.2 1.0 1.3 9.7 0.1 3.8 2 2 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16332.1 - 0.012 16.0 0.4 47 5.0 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KDO16332.1 - 0.04 14.5 1.7 5.9 7.5 1.4 3.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) UTP15_C PF09384.10 KDO16332.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 UTP15 C terminal MFS_1 PF07690.16 KDO16333.1 - 1e-10 41.1 23.0 1.8e-09 37.0 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO16333.1 - 3.1e-09 36.2 14.3 3.8e-09 35.9 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4231 PF14015.6 KDO16333.1 - 0.14 12.6 2.7 0.48 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Sugar_tr PF00083.24 KDO16334.1 - 1.3e-26 93.5 10.6 1.5e-26 93.3 10.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO16334.1 - 9.8e-26 90.5 19.3 1.2e-25 90.2 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KDO16334.1 - 2e-05 23.3 3.7 2.1e-05 23.1 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KDO16334.1 - 3.3e-05 23.4 10.4 4.2e-05 23.0 10.4 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB zf-C2H2 PF00096.26 KDO16336.1 - 1.2e-16 60.1 27.4 0.0013 19.0 2.7 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO16336.1 - 6e-12 45.4 28.4 1.4e-05 25.2 2.4 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO16336.1 - 5.8e-08 32.9 34.1 0.03 15.1 1.7 5.7 6 0 0 6 6 5 5 C2H2-type zinc finger FOXP-CC PF16159.5 KDO16336.1 - 0.0018 18.9 13.4 6.8 7.4 0.1 5.0 2 1 3 5 5 5 3 FOXP coiled-coil domain zf-met PF12874.7 KDO16336.1 - 0.0026 18.1 10.5 0.54 10.7 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KDO16336.1 - 0.0095 16.6 13.6 0.08 13.6 2.9 2.7 3 0 0 3 3 3 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 KDO16336.1 - 0.011 16.0 9.9 3.9 7.8 0.9 3.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KDO16336.1 - 0.06 13.1 27.9 0.11 12.3 0.7 5.0 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KDO16336.1 - 0.1 12.9 14.1 0.53 10.6 0.2 5.4 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF842 PF05811.13 KDO16336.1 - 0.46 10.2 2.4 13 5.5 0.3 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) zf-C2H2_aberr PF17017.5 KDO16336.1 - 0.52 10.4 9.9 19 5.4 0.1 3.7 1 1 2 4 4 4 0 Aberrant zinc-finger CCAP PF11105.8 KDO16336.1 - 1.4 8.9 3.4 1.1 9.2 0.2 2.0 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a U-box PF04564.15 KDO16337.1 - 1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO16337.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF853 PF05872.12 KDO16337.1 - 0.084 11.4 0.1 0.096 11.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FAA_hydrolase PF01557.18 KDO16338.1 - 3.9e-59 199.9 0.0 5.1e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KDO16338.1 - 2.4e-31 108.1 0.0 4.8e-31 107.1 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal TPR_12 PF13424.6 KDO16339.1 - 2.6e-05 24.4 0.1 3.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO16339.1 - 0.0015 18.0 1.0 0.0016 17.9 1.0 1.0 1 0 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 KDO16339.1 - 0.0022 17.8 0.1 0.066 13.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat FAM194 PF14977.6 KDO16340.1 - 1.5e-06 27.7 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FAM194 protein SelR PF01641.18 KDO16340.1 - 4e-06 26.9 0.0 7.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SelR domain Helicase_C PF00271.31 KDO16341.1 - 4.1e-15 56.1 0.1 8.5e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KDO16341.1 - 0.069 12.3 0.0 0.082 12.1 0.0 1.3 1 1 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ANAPC4_WD40 PF12894.7 KDO16343.1 - 8.2e-06 26.0 0.1 4.4 7.7 0.0 4.2 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO16343.1 - 0.0017 19.1 2.8 0.94 10.5 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KDO16343.1 - 0.0035 17.4 0.0 0.0098 15.9 0.0 1.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Hist_deacetyl PF00850.19 KDO16344.1 - 4.5e-20 72.3 0.0 7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Tim17 PF02466.19 KDO16346.1 - 1.1e-19 70.9 7.4 1.3e-19 70.6 7.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KDO16346.1 - 0.0013 19.0 7.3 0.16 12.4 3.7 2.8 2 1 1 3 3 3 2 Reactive mitochondrial oxygen species modulator 1 ABC_tran PF00005.27 KDO16349.1 - 1.9e-09 38.2 0.0 9.5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KDO16349.1 - 0.045 13.5 0.0 0.086 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Lipocalin_3 PF12702.7 KDO16349.1 - 0.073 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipocalin-like SMC_N PF02463.19 KDO16349.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KDO16349.1 - 0.095 12.9 1.0 1.1 9.6 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KDO16350.1 - 2.9e-44 150.7 0.0 5.1e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO16350.1 - 2.7e-06 27.2 0.1 3.5e-05 23.6 0.0 2.5 3 1 1 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KDO16350.1 - 3e-06 27.7 2.0 0.0013 19.1 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain Vps4_C PF09336.10 KDO16350.1 - 0.00011 22.1 0.0 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 KDO16350.1 - 0.00016 22.2 0.0 0.00027 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KDO16350.1 - 0.00019 21.2 1.1 0.78 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain IstB_IS21 PF01695.17 KDO16350.1 - 0.00023 20.9 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO16350.1 - 0.00054 20.2 0.1 0.0069 16.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KDO16350.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KDO16350.1 - 0.0022 18.0 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KDO16350.1 - 0.0024 18.0 0.0 0.39 10.8 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain ATPase PF06745.13 KDO16350.1 - 0.0026 17.2 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 KaiC Parvo_NS1 PF01057.17 KDO16350.1 - 0.0032 16.6 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 KDO16350.1 - 0.0034 17.4 0.2 0.02 14.9 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KDO16350.1 - 0.0039 16.6 0.0 0.0095 15.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KDO16350.1 - 0.0043 17.4 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KDO16350.1 - 0.0049 17.0 0.0 0.044 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KDO16350.1 - 0.0091 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KDO16350.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KDO16350.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KDO16350.1 - 0.014 15.5 0.0 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO16350.1 - 0.02 14.5 0.7 0.039 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO16350.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO16350.1 - 0.021 14.7 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KDO16350.1 - 0.022 15.3 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KDO16350.1 - 0.027 14.2 0.0 0.12 12.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KDO16350.1 - 0.028 14.7 3.4 1 9.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.11 KDO16350.1 - 0.037 13.9 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KDO16350.1 - 0.038 13.7 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KDO16350.1 - 0.043 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KDO16350.1 - 0.047 12.9 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KDO16350.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO16350.1 - 0.17 11.0 0.0 0.43 9.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain CbiG_C PF01890.16 KDO16350.1 - 0.68 10.5 3.4 3.4 8.3 1.5 2.6 2 1 1 3 3 2 0 Cobalamin synthesis G C-terminus Nuc_sug_transp PF04142.15 KDO16352.1 - 2.2e-06 27.1 3.6 2.7e-06 26.8 3.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF5326 PF17260.2 KDO16352.1 - 1.4 9.1 4.1 0.82 9.9 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Tim17 PF02466.19 KDO16353.1 - 0.00029 21.2 0.2 0.0021 18.4 0.1 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family LRR_4 PF12799.7 KDO16355.1 - 1.2e-07 31.9 4.9 0.00016 21.9 0.7 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO16355.1 - 1.1e-05 25.0 4.3 0.0047 16.7 0.2 3.1 1 1 2 3 3 3 3 Leucine rich repeat Pkinase_Tyr PF07714.17 KDO16355.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 KDO16355.1 - 0.018 15.0 0.8 7.2 6.9 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat Nuc_deoxyri_tr2 PF15891.5 KDO16356.1 - 5.4e-08 33.1 0.5 1.2e-05 25.5 0.2 2.3 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like HECT PF00632.25 KDO16358.1 - 9.1e-75 252.0 0.0 1.3e-74 251.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO16358.1 - 1.5e-06 27.4 1.1 3.1e-06 26.4 1.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others KIX_2 PF16987.5 KDO16359.1 - 0.057 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 KIX domain HEAT PF02985.22 KDO16363.1 - 0.0067 16.6 3.7 2.5 8.6 0.1 3.6 4 1 1 5 5 5 2 HEAT repeat ABG_transport PF03806.13 KDO16363.1 - 0.16 10.2 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Arrestin_N PF00339.29 KDO16364.1 - 1.3e-10 41.5 0.0 1.6e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 KDO16365.1 - 5e-17 62.3 0.0 7e-14 52.1 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KDO16365.1 - 3.7e-08 33.9 0.0 1.2e-07 32.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KDO16365.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like DUF2574 PF10836.8 KDO16365.1 - 0.033 14.1 0.2 0.088 12.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Rgp1 PF08737.10 KDO16365.1 - 0.1 11.8 2.0 0.33 10.1 0.6 2.3 2 1 1 3 3 3 0 Rgp1 EGF_2 PF07974.13 KDO16366.1 - 2.3e-12 47.0 108.7 0.00052 20.3 7.3 9.4 10 0 0 10 10 10 7 EGF-like domain hEGF PF12661.7 KDO16366.1 - 5e-07 30.1 89.2 0.0037 17.8 5.5 9.3 8 0 0 8 8 8 6 Human growth factor-like EGF EGF PF00008.27 KDO16366.1 - 3.6e-06 27.2 87.9 0.00034 20.8 3.7 8.6 8 0 0 8 8 8 6 EGF-like domain DUF3000 PF11452.8 KDO16368.1 - 0.2 11.2 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) HEAT PF02985.22 KDO16369.1 - 1.4e-05 24.9 2.9 0.008 16.4 0.2 4.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KDO16369.1 - 0.017 15.5 4.7 2.4 8.6 0.1 4.6 4 2 0 4 4 4 0 HEAT repeats Arm PF00514.23 KDO16369.1 - 0.034 14.2 0.8 0.33 11.1 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KDO16369.1 - 0.086 13.4 4.7 8.2 7.1 0.1 4.7 3 2 2 5 5 5 0 HEAT-like repeat Pet191_N PF10203.9 KDO16370.1 - 3.8e-23 81.5 9.0 4.3e-23 81.4 9.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 cNMP_binding PF00027.29 KDO16371.1 - 2.4e-16 59.5 0.1 4.3e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO16371.1 - 8.4e-05 21.9 0.5 0.00014 21.2 0.5 1.3 1 0 0 1 1 1 1 Ion transport protein DUF2281 PF10047.9 KDO16371.1 - 0.056 14.2 0.7 6.3 7.6 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2281) DEAD_2 PF06733.15 KDO16373.1 - 2.5e-49 167.3 0.5 3.7e-49 166.7 0.5 1.3 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 KDO16373.1 - 0.003 17.4 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KDO16373.1 - 0.012 15.7 1.7 0.16 12.0 0.2 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KDO16373.1 - 0.1 12.0 0.0 2.3 7.6 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein RtcB PF01139.17 KDO16374.1 - 1.7e-06 27.5 2.1 2e-06 27.3 2.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB PRP38 PF03371.15 KDO16376.1 - 5e-56 189.3 0.1 5.7e-56 189.1 0.1 1.0 1 0 0 1 1 1 1 PRP38 family PBP1_TM PF14812.6 KDO16376.1 - 9.1 6.7 12.6 16 6.0 12.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF998 PF06197.13 KDO16377.1 - 0.012 15.2 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Mito_carr PF00153.27 KDO16378.1 - 2.1e-23 82.1 0.1 2.4e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein RabGAP-TBC PF00566.18 KDO16379.1 - 1.5e-14 54.2 0.0 2.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HA PF03457.14 KDO16380.1 - 2.6e-19 69.3 0.5 0.00099 19.4 0.0 7.2 7 0 0 7 7 7 6 Helicase associated domain HYLS1_C PF15311.6 KDO16380.1 - 0.14 12.9 0.1 48 4.8 0.0 4.2 5 0 0 5 5 5 0 Hydrolethalus syndrome protein 1 C-terminus HA PF03457.14 KDO16381.1 - 0.0061 16.9 0.0 0.0079 16.5 0.0 1.2 1 0 0 1 1 1 1 Helicase associated domain Spt20 PF12090.8 KDO16382.1 - 2.2 7.8 10.2 2.3 7.8 10.2 1.1 1 0 0 1 1 1 0 Spt20 family Polyketide_cyc PF03364.20 KDO16383.1 - 1.9e-24 86.3 0.2 2.9e-24 85.7 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KDO16383.1 - 8.8e-07 29.3 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EF-hand_1 PF00036.32 KDO16383.1 - 8e-05 21.9 0.1 0.00072 18.9 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO16383.1 - 0.00028 20.6 0.1 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KDO16383.1 - 0.00044 19.6 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KDO16383.1 - 0.013 15.9 0.3 0.13 12.7 0.3 2.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KDO16383.1 - 0.03 14.2 0.1 0.085 12.7 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain pair Mito_carr PF00153.27 KDO16385.1 - 4.5e-10 39.3 0.5 3.4e-08 33.3 0.5 2.0 1 1 0 1 1 1 1 Mitochondrial carrier protein ETF PF01012.21 KDO16385.1 - 0.074 12.9 0.1 0.08 12.8 0.1 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Mo25 PF08569.11 KDO16386.1 - 2.4e-08 33.7 0.0 3e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like DUF3412 PF11892.8 KDO16386.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3412) AAA_lid_3 PF17862.1 KDO16387.1 - 5e-10 39.0 0.0 7.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KDO16387.1 - 4.2e-09 36.9 0.1 5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TP_methylase PF00590.20 KDO16388.1 - 6.4e-22 78.5 0.0 6.8e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DHH PF01368.20 KDO16388.1 - 0.048 13.9 0.0 0.18 12.0 0.0 1.8 1 1 1 2 2 2 0 DHH family CMD PF02627.20 KDO16389.1 - 0.16 12.0 5.4 0.39 10.8 0.3 3.1 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family Spc7 PF08317.11 KDO16390.1 - 0.028 13.3 1.2 0.045 12.6 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1515 PF07439.11 KDO16390.1 - 0.033 14.2 0.5 0.055 13.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) LPP PF04728.13 KDO16391.1 - 0.0087 16.4 0.5 0.0087 16.4 0.5 7.0 6 2 2 8 8 7 1 Lipoprotein leucine-zipper TMF_TATA_bd PF12325.8 KDO16391.1 - 0.093 12.9 54.0 1.1 9.5 2.6 6.3 3 2 3 6 6 6 0 TATA element modulatory factor 1 TATA binding HOOK PF05622.12 KDO16391.1 - 0.12 10.5 48.6 0.0056 14.9 12.6 3.7 2 1 1 3 3 3 0 HOOK protein Reprolysin_4 PF13583.6 KDO16391.1 - 0.33 10.6 6.0 1 9.0 6.0 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fez1 PF06818.15 KDO16391.1 - 0.63 10.5 48.2 0.18 12.2 12.2 4.4 3 2 2 5 5 5 0 Fez1 NAD_binding_6 PF08030.12 KDO16391.1 - 0.68 10.0 3.0 0.4 10.8 0.4 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NPV_P10 PF05531.12 KDO16391.1 - 1.4 9.4 27.4 0.19 12.2 1.3 5.4 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 KDO16391.1 - 3 8.0 34.4 5.8 7.1 0.2 6.8 5 2 1 6 6 6 0 TolA binding protein trimerisation Phage_tail_T PF06223.12 KDO16391.1 - 4.3 7.9 7.8 29 5.3 0.5 4.2 2 1 1 3 3 3 0 Minor tail protein T Mt_ATP-synt_D PF05873.12 KDO16391.1 - 6.1 6.7 12.6 3.8 7.3 4.6 3.1 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Lipoprotein_6 PF01441.19 KDO16391.1 - 9.1 6.3 17.2 0.094 12.7 3.2 3.4 2 1 1 3 3 3 0 Lipoprotein DUF2680 PF10925.8 KDO16391.1 - 9.5 6.3 9.5 56 3.9 0.1 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) PHC2_SAM_assoc PF16616.5 KDO16392.1 - 0.13 13.1 4.0 0.23 12.3 4.0 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 FAM76 PF16046.5 KDO16392.1 - 1.2 8.5 12.9 1.4 8.2 12.9 1.1 1 0 0 1 1 1 0 FAM76 protein DUF5327 PF17261.2 KDO16392.1 - 1.5 9.6 8.2 0.22 12.3 3.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5327) FKBP_N PF01346.18 KDO16392.1 - 8.8 7.4 12.0 2.9 8.9 4.5 2.4 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peptidase_C69 PF03577.15 KDO16394.1 - 4e-34 118.2 0.0 6.1e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 KDO16394.1 - 0.12 12.3 0.2 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Phage Head-Tail Attachment DUF1419 PF07215.11 KDO16394.1 - 0.16 12.1 0.1 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) DUF3708 PF12501.8 KDO16394.1 - 0.65 9.8 3.9 3.6 7.3 0.9 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Mito_morph_reg PF14972.6 KDO16395.1 - 0.0083 15.7 0.9 0.0089 15.6 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator Trypsin_2 PF13365.6 KDO16396.1 - 2.3e-17 64.3 0.2 4.5e-17 63.3 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ricin_B_lectin PF00652.22 KDO16396.1 - 2.6e-10 40.6 0.6 7.2e-10 39.2 0.6 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO16396.1 - 0.00026 21.6 1.0 0.002 18.8 1.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO16396.1 - 0.0041 16.7 0.1 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain Peptidase_S46 PF10459.9 KDO16396.1 - 0.14 10.8 1.9 2.7 6.5 0.4 2.3 2 0 0 2 2 2 0 Peptidase S46 DZR PF12773.7 KDO16398.1 - 0.052 13.6 0.4 0.08 13.0 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon PknG_rubred PF16919.5 KDO16398.1 - 0.11 12.7 1.2 0.15 12.2 1.2 1.2 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Sugar_tr PF00083.24 KDO16399.1 - 2.2e-10 40.0 0.2 2.4e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2062 PF09835.9 KDO16400.1 - 2.7e-12 46.8 8.8 3.4e-12 46.5 8.8 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) TMEM208_SND2 PF05620.11 KDO16400.1 - 0.6 9.9 2.9 0.82 9.4 2.9 1.3 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 BT1 PF03092.16 KDO16403.1 - 1e-08 33.9 0.5 1.1e-08 33.7 0.5 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 KDO16403.1 - 0.00017 20.6 0.5 0.00017 20.6 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 KDO16403.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 VIT family Ank_2 PF12796.7 KDO16404.1 - 8.7e-07 29.5 0.0 1e-06 29.2 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16404.1 - 6.7e-06 26.6 0.1 0.0034 17.9 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16404.1 - 8e-05 22.8 0.1 0.014 15.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16404.1 - 0.0019 18.6 0.2 0.0074 16.7 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeat PX PF00787.24 KDO16406.1 - 5.8e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PX domain EGF_2 PF07974.13 KDO16407.1 - 1.3e-05 25.5 29.5 5.4e-05 23.5 14.0 2.9 1 1 1 2 2 2 2 EGF-like domain cEGF PF12662.7 KDO16407.1 - 0.011 15.7 11.6 0.51 10.3 1.4 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF PF00008.27 KDO16407.1 - 0.016 15.5 13.4 0.016 15.5 13.4 2.7 2 1 0 2 2 2 0 EGF-like domain EB PF01683.18 KDO16407.1 - 2.7 8.3 27.3 0.98 9.8 11.0 2.6 2 1 0 2 2 2 0 EB module Laminin_EGF PF00053.24 KDO16407.1 - 5.1 7.3 26.6 1.3 9.2 12.7 2.3 1 1 1 2 2 2 0 Laminin EGF domain Glyoxalase PF00903.25 KDO16411.1 - 4.5e-09 36.6 1.0 1e-05 25.7 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KDO16411.1 - 1.9e-07 31.3 0.1 0.0012 19.1 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KDO16411.1 - 1.5e-06 28.4 0.3 3.8e-05 23.9 0.1 3.0 3 1 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KDO16411.1 - 0.057 13.5 0.3 17 5.5 0.0 3.0 3 1 0 3 3 3 0 Glyoxalase-like domain MatE PF01554.18 KDO16412.1 - 1.3e-27 96.4 5.8 2e-27 95.8 5.8 1.3 1 0 0 1 1 1 1 MatE Polysacc_synt_C PF14667.6 KDO16412.1 - 9.8e-06 25.7 6.0 9.8e-06 25.7 6.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Cation_efflux PF01545.21 KDO16413.1 - 0.00068 19.4 0.1 0.00088 19.1 0.1 1.2 1 0 0 1 1 1 1 Cation efflux family NBD_C PF17042.5 KDO16413.1 - 0.15 12.6 1.3 1.9 8.9 0.3 2.2 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain Glycos_transf_1 PF00534.20 KDO16414.1 - 6e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO16414.1 - 8.6e-07 29.5 0.0 2.7e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO16414.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 PRK PF00485.18 KDO16414.1 - 0.051 13.3 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SDF PF00375.18 KDO16415.1 - 0.00025 20.2 0.9 0.00026 20.1 0.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Cep57_CLD PF14073.6 KDO16417.1 - 6.4e-07 29.6 48.7 0.0013 18.7 8.1 3.6 1 1 3 4 4 4 2 Centrosome localisation domain of Cep57 Cast PF10174.9 KDO16417.1 - 0.00079 17.8 12.4 0.00079 17.8 12.4 3.4 1 1 2 3 3 3 2 RIM-binding protein of the cytomatrix active zone TMF_DNA_bd PF12329.8 KDO16417.1 - 0.016 15.2 0.7 0.016 15.2 0.7 6.1 3 2 4 7 7 7 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 KDO16417.1 - 0.65 9.4 49.1 1.7 8.0 6.6 3.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3698 PF12479.8 KDO16417.1 - 1.7 9.2 4.2 2.2 8.9 0.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3698) BRI3BP PF14965.6 KDO16417.1 - 2 7.9 7.6 8.1 5.9 0.4 3.5 3 0 0 3 3 3 0 Negative regulator of p53/TP53 Csm1_N PF18504.1 KDO16417.1 - 4.3 7.7 36.8 0.61 10.5 0.9 6.7 3 3 4 8 8 8 0 Csm1 N-terminal domain TPR_1 PF00515.28 KDO16418.1 - 3e-12 45.8 5.2 3.2e-07 29.9 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16418.1 - 1.1e-11 43.9 7.0 4.1e-06 26.5 0.4 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO16418.1 - 3.2e-07 29.9 4.6 3.6e-06 26.6 0.0 3.5 2 1 2 4 4 4 1 TPR repeat TPR_8 PF13181.6 KDO16418.1 - 4.2e-06 26.6 2.0 0.0048 17.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO16418.1 - 0.00011 22.3 3.9 0.08 13.1 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16418.1 - 0.00011 22.8 9.1 0.00045 20.8 0.1 3.5 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO16418.1 - 0.00011 22.4 4.2 0.003 17.8 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KDO16418.1 - 0.0028 16.9 4.6 2.2 7.4 0.0 3.5 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 KDO16418.1 - 0.0078 15.9 1.2 0.1 12.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KDO16418.1 - 0.0096 15.3 1.7 0.014 14.8 1.7 1.3 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 KDO16418.1 - 0.029 15.2 9.0 0.46 11.4 0.1 4.3 3 1 2 5 5 4 0 Tetratricopeptide repeat Apc13p PF05839.11 KDO16418.1 - 0.045 13.9 0.3 0.089 13.0 0.3 1.4 1 0 0 1 1 1 0 Apc13p protein Strep_his_triad PF04270.13 KDO16418.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Streptococcal histidine triad protein TPR_6 PF13174.6 KDO16418.1 - 0.45 11.2 5.5 1.5 9.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO16418.1 - 2.1 8.4 4.5 24 5.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DIM1 PF02966.16 KDO16419.1 - 5.2e-47 159.0 0.3 6.1e-47 158.7 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KDO16419.1 - 0.0037 17.2 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Gemini_AC4_5_2 PF08464.10 KDO16420.1 - 0.065 13.2 0.1 0.084 12.8 0.1 1.1 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region CBM_1 PF00734.18 KDO16421.1 - 2.7e-25 88.0 43.7 2e-10 40.4 10.4 5.0 5 0 0 5 5 5 4 Fungal cellulose binding domain VP4_2 PF08935.10 KDO16421.1 - 0.019 15.5 0.6 0.055 14.1 0.1 2.0 3 0 0 3 3 3 0 Viral protein VP4 subunit Toxin_7 PF05980.12 KDO16421.1 - 0.039 14.2 0.5 0.039 14.2 0.5 3.5 4 0 0 4 4 4 0 Toxin 7 HOCHOB PF17943.1 KDO16421.1 - 0.2 12.4 12.5 3.1 8.5 0.3 3.2 2 1 1 3 3 3 0 Homeobox-cysteine loop-homeobox UCR_hinge PF02320.16 KDO16421.1 - 0.27 11.5 0.3 0.27 11.5 0.3 3.7 3 1 1 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein CBM_1 PF00734.18 KDO16422.1 - 2.8e-08 33.6 9.4 2.8e-08 33.6 9.4 4.5 5 1 1 6 6 6 1 Fungal cellulose binding domain CarbpepA_inh PF02977.15 KDO16422.1 - 0.019 14.8 0.9 0.019 14.8 0.9 3.4 3 1 0 3 3 3 0 Carboxypeptidase A inhibitor Dickkopf_N PF04706.12 KDO16422.1 - 8.6 6.9 28.8 0.25 11.9 1.7 3.9 3 2 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Abhydrolase_1 PF00561.20 KDO16423.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO16423.1 - 0.00036 19.9 0.0 0.19 10.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF3724 PF12521.8 KDO16423.1 - 0.0093 15.8 0.1 0.031 14.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3724) Abhydrolase_6 PF12697.7 KDO16423.1 - 0.07 13.7 0.0 0.23 12.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family SNF2_N PF00176.23 KDO16424.1 - 4.3e-55 186.9 0.1 8.2e-55 185.9 0.0 1.4 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO16424.1 - 3e-16 59.7 0.0 9e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO16424.1 - 1.8e-10 41.1 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO16424.1 - 3.9e-07 30.0 0.0 8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KDO16424.1 - 0.00034 19.9 0.4 0.0027 16.9 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 KDO16424.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KDO16424.1 - 0.033 13.9 0.0 0.088 12.5 0.0 1.8 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_12 PF13087.6 KDO16424.1 - 0.17 11.5 0.1 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Haem_degrading PF03928.14 KDO16427.1 - 0.055 13.5 1.6 0.068 13.2 1.6 1.3 1 1 0 1 1 1 0 Haem-degrading DUF3228 PF11539.8 KDO16428.1 - 8.3e-76 253.8 0.0 9.7e-76 253.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) LRR_4 PF12799.7 KDO16430.1 - 2.3e-37 126.4 39.7 6.4e-09 35.9 0.6 7.2 3 1 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO16430.1 - 3.4e-22 78.0 26.4 2.2e-06 27.4 1.6 5.8 1 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KDO16430.1 - 6.3e-21 74.6 11.4 6.7e-12 45.3 0.9 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KDO16430.1 - 2.5e-05 24.2 19.7 6.5 7.7 0.2 9.4 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KDO16430.1 - 0.0036 17.2 22.4 2.1 8.6 0.0 8.9 10 0 0 10 10 10 1 Leucine Rich repeat DUF2322 PF10084.9 KDO16430.1 - 0.13 12.3 1.5 1.8 8.6 0.0 3.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) Glycos_transf_1 PF00534.20 KDO16432.1 - 0.00023 20.8 0.1 0.00065 19.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO16432.1 - 0.029 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ank_2 PF12796.7 KDO16434.1 - 2.9e-18 66.2 0.8 1e-08 35.6 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO16434.1 - 2.2e-14 53.3 3.0 4.3e-06 26.9 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO16434.1 - 7e-14 52.0 0.5 1.4e-06 28.7 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16434.1 - 2.9e-13 48.7 1.0 6.3e-05 23.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO16434.1 - 2.7e-12 46.5 3.3 3.7e-06 27.1 0.2 3.6 4 0 0 4 4 4 2 Ankyrin repeat LTXXQ PF07813.12 KDO16436.1 - 0.091 13.5 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein DEK_C PF08766.11 KDO16437.1 - 6.2e-05 22.8 1.3 6.2e-05 22.8 1.3 1.8 2 0 0 2 2 2 1 DEK C terminal domain RWP-RK PF02042.15 KDO16439.1 - 6.9e-12 45.2 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain Sugar_tr PF00083.24 KDO16440.1 - 4.9e-41 141.0 28.4 7.6e-26 91.0 6.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO16440.1 - 3.2e-29 102.0 56.4 9.6e-26 90.5 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KDO16440.1 - 0.0027 16.0 0.6 0.0054 15.0 0.6 1.4 1 0 0 1 1 1 1 BT1 family MFS_2 PF13347.6 KDO16440.1 - 0.0041 15.7 7.0 0.0041 15.7 7.0 3.0 1 1 1 3 3 3 1 MFS/sugar transport protein DUF4293 PF14126.6 KDO16440.1 - 0.48 10.7 7.9 0.45 10.8 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) TRP PF06011.12 KDO16441.1 - 9.4e-07 27.9 8.8 1.1e-06 27.7 8.8 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF1422 PF07226.11 KDO16441.1 - 0.089 12.8 10.7 1.5 8.8 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) OppC_N PF12911.7 KDO16441.1 - 7.8 6.6 7.1 0.93 9.5 0.7 2.5 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C CorA PF01544.18 KDO16442.1 - 4e-09 36.2 3.1 5.4e-09 35.8 3.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CDC45 PF02724.14 KDO16443.1 - 7.3e-171 569.7 0.4 1.6e-170 568.6 0.4 1.5 1 1 0 1 1 1 1 CDC45-like protein U3_snoRNA_assoc PF08297.11 KDO16443.1 - 0.012 16.3 0.4 0.012 16.3 0.4 1.6 2 0 0 2 2 2 0 U3 snoRNA associated U-box PF04564.15 KDO16444.1 - 3.8e-19 68.6 0.0 5.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO16444.1 - 6e-06 26.0 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO16444.1 - 0.0079 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF2576 PF10845.8 KDO16444.1 - 0.077 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) NOA36 PF06524.12 KDO16446.1 - 0.039 13.3 6.9 0.051 12.9 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 KDO16446.1 - 0.42 10.9 5.8 0.74 10.1 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) 60KD_IMP PF02096.20 KDO16447.1 - 2.2e-06 27.7 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Pkinase PF00069.25 KDO16448.1 - 3.7e-68 229.7 0.0 4.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16448.1 - 2.4e-29 102.4 0.0 4e-29 101.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO16448.1 - 0.0047 16.3 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO16448.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO16448.1 - 0.022 14.7 1.6 0.52 10.2 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO16448.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Hid1 PF12722.7 KDO16448.1 - 0.35 9.0 1.4 4 5.4 0.0 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Lectin_C PF00059.21 KDO16449.1 - 0.085 13.6 0.3 0.18 12.5 0.1 1.7 2 0 0 2 2 2 0 Lectin C-type domain EF-hand_6 PF13405.6 KDO16450.1 - 0.028 14.4 0.3 0.4 10.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 KDO16450.1 - 0.044 13.3 0.5 0.7 9.5 0.0 2.7 3 0 0 3 3 3 0 EF hand EF-hand_1 PF00036.32 KDO16450.1 - 0.14 11.8 0.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF1778 PF08681.11 KDO16451.1 - 0.077 12.9 0.1 0.2 11.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1778) DUF3944 PF13099.6 KDO16451.1 - 0.24 11.3 0.2 1.9 8.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3944) Peptidase_S28 PF05577.12 KDO16452.1 - 5.1e-19 68.4 0.1 6.5e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Thiolase_N PF00108.23 KDO16454.1 - 1.8e-28 99.6 0.1 2e-28 99.5 0.1 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain CHAT PF12770.7 KDO16455.1 - 0.081 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 CHAT domain Ank_2 PF12796.7 KDO16456.1 - 0.00029 21.4 0.0 0.24 12.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16456.1 - 0.01 16.4 0.7 0.78 10.4 0.6 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16456.1 - 0.095 13.1 4.1 11 6.5 0.7 3.6 2 2 2 4 4 4 0 Ankyrin repeats (many copies) LisH_2 PF16045.5 KDO16456.1 - 0.2 10.7 0.1 11 5.2 0.0 2.3 2 0 0 2 2 2 0 LisH HEAT PF02985.22 KDO16458.1 - 1.3e-10 40.6 17.2 0.0069 16.5 0.0 8.4 8 1 1 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KDO16458.1 - 4.9e-10 39.7 10.6 0.16 12.5 0.1 6.9 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 KDO16458.1 - 4.9e-07 30.1 11.7 0.067 13.6 0.2 6.0 5 2 1 6 6 6 1 HEAT repeats RTP1_C1 PF10363.9 KDO16458.1 - 3.2e-06 27.3 7.3 0.002 18.3 0.2 4.8 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KDO16458.1 - 0.00039 20.5 13.1 0.65 10.0 0.7 5.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KDO16458.1 - 0.004 17.0 9.6 3.4 7.6 0.0 5.6 5 2 1 6 6 6 1 UME (NUC010) domain Sec7_N PF12783.7 KDO16458.1 - 0.0075 16.2 5.6 15 5.5 0.0 5.9 5 2 1 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Dopey_N PF04118.14 KDO16458.1 - 0.01 15.0 7.5 0.7 9.0 2.0 4.3 2 2 1 3 3 3 0 Dopey, N-terminal HEAT_UF PF18817.1 KDO16458.1 - 0.011 15.9 0.4 0.085 13.1 0.2 2.6 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 CLASP_N PF12348.8 KDO16458.1 - 0.015 14.9 5.0 2.5 7.6 0.0 4.3 3 2 1 4 4 4 0 CLASP N terminal DUF3385 PF11865.8 KDO16458.1 - 0.04 13.8 7.2 3.8 7.4 0.0 5.7 4 2 3 8 8 8 0 Domain of unknown function (DUF3385) SwrA PF17423.2 KDO16458.1 - 0.088 12.8 0.6 3.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Swarming motility protein Tti2 PF10521.9 KDO16458.1 - 0.1 12.1 9.6 2.6 7.5 0.0 4.9 4 2 1 5 5 5 0 Tti2 family MMS19_N PF14500.6 KDO16458.1 - 0.27 10.8 11.8 2.7 7.5 0.0 5.0 4 2 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Pes-10 PF07149.11 KDO16458.1 - 0.56 9.2 4.4 4.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Pes-10 RasGEF_N_2 PF14663.6 KDO16458.1 - 7.4 7.0 6.2 14 6.1 0.1 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Stevor PF17410.2 KDO16460.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4094 PF13334.6 KDO16460.1 - 0.031 14.7 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Nucleoporin2 PF04096.14 KDO16461.1 - 1.3e-06 28.6 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase TLD PF07534.16 KDO16462.1 - 7.1e-31 107.3 0.0 1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 TLD EF-hand_6 PF13405.6 KDO16462.1 - 0.093 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KDO16462.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 EF hand zf-RING_2 PF13639.6 KDO16463.1 - 1.8e-13 50.6 5.4 3.2e-13 49.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO16463.1 - 7.2e-11 41.8 6.3 1.3e-10 40.9 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO16463.1 - 5.3e-10 39.0 3.8 9.1e-10 38.3 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO16463.1 - 5.2e-09 36.2 6.9 1.2e-08 35.1 6.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO16463.1 - 5.4e-09 35.8 4.7 1.1e-08 34.8 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO16463.1 - 1.1e-08 34.9 1.5 1.1e-08 34.9 1.5 1.8 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO16463.1 - 1.2e-07 31.5 4.6 1.2e-07 31.5 4.6 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KDO16463.1 - 1.6e-07 30.9 2.6 1.6e-07 30.9 2.6 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KDO16463.1 - 2.2e-05 24.5 0.9 6.8e-05 22.9 1.1 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO16463.1 - 0.00018 21.4 4.9 0.00032 20.6 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KDO16463.1 - 0.0029 17.2 6.4 0.006 16.2 6.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO16463.1 - 0.0067 16.4 6.3 0.021 14.9 6.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 KDO16463.1 - 0.014 15.6 0.0 0.092 12.9 0.0 2.2 3 0 0 3 3 3 0 U-box domain RINGv PF12906.7 KDO16463.1 - 0.021 14.9 2.6 0.059 13.5 2.6 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO16463.1 - 0.15 12.3 5.7 3.5 7.9 5.7 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 KDO16463.1 - 0.38 10.7 3.1 0.76 9.7 3.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.11 KDO16463.1 - 1.4 9.3 6.0 3 8.2 6.0 1.6 1 1 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KDO16463.1 - 1.5 8.7 5.3 0.72 9.7 2.6 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KDO16463.1 - 3.6 7.7 13.0 0.38 10.8 5.5 2.7 2 1 1 3 3 2 0 Zinc-finger GlcNAc PF11397.8 KDO16464.1 - 1.2e-47 163.1 2.4 5e-40 138.0 2.1 2.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) FliE PF02049.18 KDO16465.1 - 0.053 13.7 0.9 0.063 13.4 0.9 1.2 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Phosphodiest PF01663.22 KDO16466.1 - 4.6e-10 39.6 0.1 5.9e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Cu-oxidase PF00394.22 KDO16467.1 - 6.7e-37 127.1 0.1 1.3e-35 122.9 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KDO16467.1 - 5.5e-36 123.2 8.0 1.2e-33 115.6 0.7 4.2 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KDO16467.1 - 3e-31 108.0 12.7 6.5e-28 97.2 1.6 3.7 3 1 0 3 3 3 2 Multicopper oxidase HEAT_EZ PF13513.6 KDO16468.1 - 0.00014 22.3 0.6 0.06 13.9 0.1 3.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KDO16468.1 - 0.00027 21.3 2.0 0.0013 19.1 2.0 2.1 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KDO16468.1 - 0.014 15.6 0.7 0.12 12.7 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat CPP1-like PF11833.8 KDO16468.1 - 0.036 13.7 0.3 0.06 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4614 PF15391.6 KDO16468.1 - 0.2 11.6 1.2 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) PQQ_3 PF13570.6 KDO16469.1 - 0.083 13.4 4.4 0.92 10.1 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain MMR_HSR1_Xtn PF16897.5 KDO16473.1 - 2.8e-41 139.8 0.8 5e-41 139.0 0.8 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KDO16473.1 - 4.3e-20 71.9 0.0 9.5e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KDO16473.1 - 9.9e-19 67.2 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KDO16473.1 - 3e-10 39.9 0.1 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KDO16473.1 - 0.00045 19.3 0.2 0.0038 16.3 0.2 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KDO16473.1 - 0.0012 18.9 1.0 0.29 11.2 0.0 2.6 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KDO16473.1 - 0.064 12.8 1.2 2.3 7.7 1.2 3.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KDO16473.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Ank_2 PF12796.7 KDO16475.1 - 9.3e-42 141.5 0.4 1.3e-16 61.0 0.0 4.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16475.1 - 5e-34 116.2 7.3 7.5e-09 36.0 0.1 7.0 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16475.1 - 4.2e-26 90.7 9.2 8.8e-08 32.3 0.1 6.1 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO16475.1 - 3.6e-25 87.2 13.2 8.4e-05 22.8 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 KDO16475.1 - 1.6e-21 74.0 6.3 0.00031 21.0 0.0 8.5 9 0 0 9 9 9 4 Ankyrin repeat WW PF00397.26 KDO16475.1 - 0.00022 21.3 0.7 0.00041 20.4 0.7 1.5 1 0 0 1 1 1 1 WW domain Herpes_TK_C PF08465.10 KDO16476.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal DUF4477 PF14780.6 KDO16477.1 - 7.8e-06 25.6 2.1 9.6e-06 25.3 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Sas10_Utp3 PF04000.15 KDO16477.1 - 0.03 14.9 0.1 0.84 10.3 0.0 2.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family GAT PF03127.14 KDO16477.1 - 0.056 13.8 0.5 0.2 12.0 0.2 1.9 1 1 1 2 2 2 0 GAT domain FlgN PF05130.12 KDO16477.1 - 0.085 13.4 2.4 0.15 12.6 2.4 1.3 1 0 0 1 1 1 0 FlgN protein Claudin_3 PF06653.11 KDO16479.1 - 4.5 7.2 12.8 0.064 13.2 2.2 2.3 1 1 0 2 2 2 0 Tight junction protein, Claudin-like Abhydrolase_6 PF12697.7 KDO16481.1 - 0.024 15.2 4.0 0.046 14.3 4.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KDO16481.1 - 0.032 13.9 0.2 0.074 12.8 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein Ion_trans PF00520.31 KDO16485.1 - 4.3e-55 186.6 31.6 1.1e-39 136.1 19.0 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KDO16485.1 - 6.8e-08 31.6 29.1 8.2e-07 28.0 8.0 4.2 3 1 1 4 4 4 3 Polycystin cation channel START PF01852.19 KDO16486.1 - 5.2e-12 45.6 0.0 7.9e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 START domain CDC45 PF02724.14 KDO16487.1 - 0.006 14.9 11.0 0.0065 14.8 11.0 1.1 1 0 0 1 1 1 1 CDC45-like protein RLI PF04068.15 KDO16487.1 - 1.4 8.8 11.6 35 4.3 9.8 2.9 2 0 0 2 2 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI V-SNARE PF05008.15 KDO16488.1 - 8.2e-05 22.9 0.2 0.00012 22.4 0.2 1.3 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus FAM184 PF15665.5 KDO16488.1 - 0.038 13.8 0.1 0.046 13.5 0.1 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B MukF_M PF17192.4 KDO16488.1 - 0.05 13.3 0.2 0.062 13.0 0.2 1.2 1 0 0 1 1 1 0 MukF middle domain GP41 PF00517.17 KDO16488.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 Retroviral envelope protein DUF1216 PF06746.11 KDO16488.1 - 0.14 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) zf-CCCH PF00642.24 KDO16489.1 - 2e-15 56.2 18.0 2e-05 24.3 0.4 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO16489.1 - 1.6e-14 53.4 20.2 1.7e-05 24.7 4.3 3.5 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 KDO16489.1 - 1.6e-12 48.0 11.0 0.00034 21.3 0.7 3.3 2 1 1 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 KDO16489.1 - 6.2e-11 41.8 21.1 0.00062 19.5 4.5 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KDO16489.1 - 0.0041 17.3 12.9 0.0063 16.7 5.7 2.3 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KDO16489.1 - 0.021 15.3 11.8 3.3 8.3 0.2 4.1 3 1 1 4 4 4 0 RNA-binding, Nab2-type zinc finger V-SNARE_C PF12352.8 KDO16490.1 - 7.6e-09 35.7 1.0 9.5e-09 35.4 1.0 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.12 KDO16490.1 - 6.2e-05 23.0 1.6 7.5e-05 22.8 1.6 1.1 1 0 0 1 1 1 1 Laminin Domain II SNARE PF05739.19 KDO16490.1 - 0.00058 19.8 3.5 0.0034 17.3 0.8 2.4 2 1 0 2 2 2 1 SNARE domain DUF745 PF05335.13 KDO16490.1 - 0.012 15.4 2.0 0.013 15.2 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DLP_helical PF18709.1 KDO16490.1 - 0.021 14.0 0.4 0.027 13.7 0.4 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain KxDL PF10241.9 KDO16490.1 - 0.063 13.6 0.4 0.089 13.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF1664 PF07889.12 KDO16490.1 - 0.064 13.3 0.4 0.074 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3053 PF11254.8 KDO16490.1 - 0.14 11.7 0.9 0.17 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Alanine_zipper PF11839.8 KDO16490.1 - 0.18 12.2 2.4 0.34 11.3 0.1 2.0 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein zf-RING_2 PF13639.6 KDO16491.1 - 1.4e-09 38.1 4.5 2.4e-09 37.4 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO16491.1 - 1.2e-06 28.1 2.0 1.2e-06 28.1 2.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO16491.1 - 1.7e-06 28.0 4.6 8.3e-06 25.7 0.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO16491.1 - 6.6e-06 25.9 3.5 9.6e-06 25.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO16491.1 - 1.8e-05 24.6 4.5 4.3e-05 23.4 4.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO16491.1 - 2.5e-05 24.1 2.6 4.7e-05 23.2 2.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO16491.1 - 0.00023 20.9 6.6 0.001 18.8 6.7 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO16491.1 - 0.00044 20.2 0.4 0.00068 19.6 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO16491.1 - 0.00051 19.6 4.9 0.0009 18.8 4.9 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO16491.1 - 0.0014 18.5 7.1 0.0046 16.8 1.3 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KDO16491.1 - 0.004 16.9 1.2 0.0072 16.1 1.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF2225 PF09986.9 KDO16491.1 - 0.023 14.4 0.8 0.037 13.7 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-rbx1 PF12678.7 KDO16491.1 - 0.03 14.6 7.6 0.047 14.0 5.7 2.2 1 1 2 3 3 3 0 RING-H2 zinc finger domain zf-Di19 PF05605.12 KDO16491.1 - 0.067 13.5 5.5 1.2 9.4 0.7 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.6 KDO16491.1 - 0.1 12.8 6.4 0.2 11.9 6.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KDO16491.1 - 0.4 10.6 4.5 1.3 9.0 3.0 2.2 1 1 1 2 2 2 0 PHD-finger zf-TFIIB PF13453.6 KDO16491.1 - 0.64 9.4 3.3 5.1 6.5 3.3 2.2 1 1 0 1 1 1 0 Transcription factor zinc-finger Paramecium_SA PF01508.16 KDO16492.1 - 1.2 9.6 12.6 0.6 10.6 7.0 2.6 2 1 0 2 2 2 0 Paramecium surface antigen domain Transp_Tc5_C PF04236.15 KDO16492.1 - 3.5 8.1 12.1 1.6 9.2 0.1 3.8 2 1 2 4 4 4 0 Tc5 transposase C-terminal domain Senescence_reg PF04520.13 KDO16493.1 - 0.008 17.0 0.2 0.014 16.2 0.2 1.5 1 1 0 1 1 1 1 Senescence regulator RCC1 PF00415.18 KDO16494.1 - 2.8e-51 171.9 26.0 9.7e-12 45.3 0.3 8.6 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO16494.1 - 8.6e-21 73.2 43.9 7.8e-06 25.5 0.2 7.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 KDO16494.1 - 0.0052 16.5 1.8 0.0092 15.7 1.8 1.4 1 0 0 1 1 1 1 SAP domain Pox_Ag35 PF03286.14 KDO16494.1 - 0.022 14.6 4.6 0.04 13.7 4.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 KDO16494.1 - 0.027 14.2 8.2 0.051 13.3 8.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KDO16494.1 - 0.037 13.4 3.3 0.052 12.9 3.3 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 KDO16494.1 - 0.04 13.5 5.3 0.058 13.0 5.3 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KDO16494.1 - 0.055 12.8 11.4 0.085 12.2 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KDO16494.1 - 0.086 11.0 4.3 0.12 10.5 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KDO16494.1 - 0.11 10.8 4.0 0.17 10.2 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KDO16494.1 - 0.34 10.8 5.3 0.54 10.1 5.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KDO16494.1 - 0.61 8.1 14.5 0.86 7.6 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 KDO16494.1 - 3.7 7.8 13.8 6.5 6.9 13.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 KDO16494.1 - 7.3 7.3 20.4 1.4 9.6 16.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ephrin_rec_like PF07699.13 KDO16495.1 - 4.8e-05 23.0 126.9 0.0015 18.2 3.2 13.9 6 3 7 13 13 13 9 Putative ephrin-receptor like PDZ_6 PF17820.1 KDO16497.1 - 4.2e-10 39.3 0.9 0.00023 20.9 0.0 3.3 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 KDO16497.1 - 0.00016 22.0 0.0 0.04 14.3 0.0 3.2 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KDO16497.1 - 0.17 12.2 0.1 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Ion_trans_2 PF07885.16 KDO16498.1 - 2.5e-14 53.0 2.0 3.9e-14 52.4 2.0 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KDO16498.1 - 3.8e-08 32.9 0.7 5e-08 32.5 0.7 1.2 1 0 0 1 1 1 1 Ion transport protein DSHCT PF08148.12 KDO16499.1 - 1e-54 184.6 0.3 5e-54 182.4 0.3 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KDO16499.1 - 4.2e-20 72.8 0.0 5.6e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DUF3516 PF12029.8 KDO16499.1 - 0.13 11.4 0.2 0.19 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Myosin_head PF00063.21 KDO16501.1 - 3.3e-57 194.2 0.0 5.3e-57 193.5 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KDO16501.1 - 5.3e-06 26.9 0.1 2.1e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 KDO16501.1 - 0.0012 18.9 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KDO16501.1 - 0.0019 18.0 0.9 0.0037 17.0 0.9 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO16501.1 - 0.0036 17.6 0.1 0.0064 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KDO16501.1 - 0.004 16.5 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.9 KDO16501.1 - 0.0053 16.0 0.1 0.007 15.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KDO16501.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KDO16501.1 - 0.016 14.8 0.4 0.037 13.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KDO16501.1 - 0.018 14.1 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KDO16501.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 KDO16501.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 KDO16501.1 - 0.17 12.3 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KDO16501.1 - 0.21 11.6 0.1 0.38 10.8 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GYF_2 PF14237.6 KDO16502.1 - 7.9e-15 54.4 0.1 8.9e-15 54.2 0.1 1.0 1 0 0 1 1 1 1 GYF domain 2 GYF PF02213.16 KDO16502.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 GYF domain AMP-binding PF00501.28 KDO16503.1 - 1.1e-17 63.7 0.0 1.2e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TTD PF12148.8 KDO16503.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Tandem tudor domain within UHRF1 cobW PF02492.19 KDO16505.1 - 3.1e-18 66.0 1.0 3.5e-18 65.8 1.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 KDO16505.1 - 0.00016 21.5 0.1 0.00018 21.4 0.1 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KDO16505.1 - 0.0018 18.3 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KDO16505.1 - 0.0025 17.8 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KDO16505.1 - 0.0049 16.8 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KDO16505.1 - 0.006 17.0 0.0 0.0062 16.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KDO16505.1 - 0.0079 16.5 0.0 0.0098 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO16505.1 - 0.011 15.8 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO16505.1 - 0.013 15.8 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO16505.1 - 0.013 16.0 0.1 0.017 15.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO16505.1 - 0.026 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KDO16505.1 - 0.029 13.4 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KDO16505.1 - 0.033 13.9 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KDO16505.1 - 0.041 13.6 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KDO16505.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase NTPase_1 PF03266.15 KDO16505.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.6 KDO16505.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO16505.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KDO16505.1 - 0.16 12.4 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KDO16505.1 - 0.17 12.1 0.1 0.26 11.5 0.0 1.4 2 0 0 2 2 1 0 AAA domain BTB_2 PF02214.22 KDO16510.1 - 2.4e-12 47.0 0.0 3.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain EF-hand_1 PF00036.32 KDO16511.1 - 1.2e-09 37.1 0.0 0.0011 18.4 0.0 2.9 2 0 0 2 2 2 2 EF hand LRR_6 PF13516.6 KDO16511.1 - 2.4e-09 36.5 6.4 0.0038 17.2 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat EF-hand_6 PF13405.6 KDO16511.1 - 1.9e-07 30.5 0.1 0.017 15.0 0.0 3.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KDO16511.1 - 2.5e-07 31.1 0.0 9e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair DUF4476 PF14771.6 KDO16511.1 - 4.9e-05 23.5 1.4 1.3 9.3 0.0 4.3 5 0 0 5 5 5 2 Domain of unknown function (DUF4476) LRR_1 PF00560.33 KDO16511.1 - 7.8e-05 22.7 1.5 34 5.5 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat EF-hand_8 PF13833.6 KDO16511.1 - 0.00057 19.7 0.1 0.15 11.9 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO16511.1 - 0.0012 18.3 0.0 0.0035 16.8 0.0 1.9 1 0 0 1 1 1 1 EF hand LRR_4 PF12799.7 KDO16511.1 - 0.013 15.9 3.9 2.7 8.5 0.4 3.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO16511.1 - 0.038 13.8 5.1 1 9.2 1.6 3.4 1 1 1 2 2 2 0 Leucine rich repeat SDF PF00375.18 KDO16514.1 - 0.0069 15.5 0.7 0.0077 15.3 0.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LigB PF02900.18 KDO16515.1 - 7.8e-37 126.8 0.0 1e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GAPES3 PF17154.4 KDO16515.1 - 0.073 13.0 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Oxygenase-NA PF09859.9 KDO16516.1 - 0.092 12.3 0.7 0.12 11.9 0.7 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA UPF0029 PF01205.19 KDO16516.1 - 0.14 12.5 1.0 0.18 12.2 0.5 1.5 1 1 1 2 2 2 0 Uncharacterized protein family UPF0029 V_ATPase_I PF01496.19 KDO16517.1 - 2.6e-135 452.4 0.0 2.9e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YqhR PF11085.8 KDO16517.1 - 0.07 13.0 2.0 0.11 12.4 2.0 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR CDT1_C PF16679.5 KDO16517.1 - 0.73 10.3 2.6 0.61 10.6 0.2 2.1 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain RdRP PF05183.12 KDO16519.1 - 9.3e-121 404.3 0.0 1.2e-120 403.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Guanylate_cyc PF00211.20 KDO16520.1 - 4.6e-10 39.4 0.0 3.5e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2206 PF09971.9 KDO16520.1 - 0.019 13.7 0.1 0.034 12.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Ion_trans PF00520.31 KDO16520.1 - 0.044 13.0 8.9 0.059 12.6 8.5 1.5 1 1 0 1 1 1 0 Ion transport protein TPR_2 PF07719.17 KDO16520.1 - 0.083 13.0 0.1 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat VIT1 PF01988.19 KDO16521.1 - 1.2e-13 51.4 0.1 2.5e-13 50.4 0.1 1.5 1 1 0 1 1 1 1 VIT family DUF2934 PF11154.8 KDO16521.1 - 0.12 12.1 0.4 0.23 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) PRT_C PF08372.10 KDO16525.1 - 0.041 13.6 0.4 0.063 13.0 0.4 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal UQ_con PF00179.26 KDO16526.1 - 3.5e-22 78.5 0.0 5.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EF-hand_1 PF00036.32 KDO16526.1 - 1.2e-12 46.4 1.3 2.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO16526.1 - 1e-10 41.9 0.1 1.7e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO16526.1 - 1e-09 37.5 1.1 5.9e-05 22.4 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO16526.1 - 3.7e-09 35.8 0.3 0.00052 19.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO16526.1 - 1.3e-07 31.4 4.0 5e-06 26.3 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO16526.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO16526.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.32 KDO16527.1 - 0.0002 22.1 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat GFO_IDH_MocA_C PF02894.17 KDO16528.1 - 0.011 15.8 0.0 0.044 13.8 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KDO16529.1 - 0.046 14.5 0.0 0.049 14.5 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Aldedh PF00171.22 KDO16532.1 - 1.8e-09 36.6 0.0 2.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PufQ PF05398.11 KDO16533.1 - 0.049 13.8 0.2 0.093 12.9 0.2 1.5 1 0 0 1 1 1 0 PufQ cytochrome subunit AMP-binding_C PF13193.6 KDO16534.1 - 2e-14 54.3 0.0 2.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WW PF00397.26 KDO16535.1 - 1.3e-09 37.9 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 WW domain Mito_fiss_reg PF05308.11 KDO16535.1 - 0.019 15.1 2.1 0.044 13.9 2.1 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF3235 PF11574.8 KDO16535.1 - 0.078 13.9 0.1 0.078 13.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DivIC PF04977.15 KDO16535.1 - 7.5 6.4 8.7 1.8 8.4 4.6 2.1 2 1 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.6 KDO16539.1 - 2.6e-18 66.3 8.2 7.6e-17 61.5 8.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4349) PIG-Y PF15159.6 KDO16539.1 - 0.21 12.5 2.8 0.57 11.1 0.9 2.3 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PsbM PF05151.12 KDO16541.1 - 0.55 10.1 3.8 1.5 8.7 1.1 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) TBCC PF07986.12 KDO16543.1 - 1.3e-12 47.5 0.0 2.4e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor C Ank_2 PF12796.7 KDO16545.1 - 1.3e-33 115.4 5.9 1.5e-16 60.8 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) TIR_2 PF13676.6 KDO16545.1 - 9.4e-30 103.6 0.0 5.2e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 TIR domain Ank PF00023.30 KDO16545.1 - 5.7e-24 83.5 8.2 1.3e-05 25.4 0.1 6.7 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KDO16545.1 - 6.1e-22 75.4 3.4 7.5e-06 25.9 0.1 7.2 6 1 1 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KDO16545.1 - 2.2e-21 75.9 6.2 8.8e-08 32.5 0.1 5.7 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16545.1 - 4.7e-19 68.2 1.8 8.2e-09 35.6 0.1 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) TIR PF01582.20 KDO16545.1 - 2e-09 37.5 0.0 3.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 KDO16545.1 - 0.0016 18.8 0.0 1.2 9.4 0.1 3.3 3 1 0 3 3 3 1 MTH538 TIR-like domain (DUF1863) DUF3040 PF11239.8 KDO16546.1 - 0.089 13.1 0.2 0.19 12.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Glyco_trans_1_4 PF13692.6 KDO16548.1 - 1.3e-10 41.9 0.0 2.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KDO16548.1 - 3e-08 33.4 0.0 1.1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF2517 PF10725.9 KDO16548.1 - 0.035 13.9 0.0 0.75 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) DUF2807 PF10988.8 KDO16549.1 - 1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain DisA_N PF02457.16 KDO16549.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Ank_2 PF12796.7 KDO16550.1 - 1.2e-12 48.3 28.9 0.00031 21.3 0.8 4.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16550.1 - 3.4e-07 30.7 11.6 0.0011 19.5 0.3 5.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16550.1 - 2e-05 24.6 13.9 35 5.4 0.0 8.2 8 1 1 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KDO16550.1 - 0.00022 21.4 18.2 7.1 7.1 0.1 7.7 3 2 4 8 8 8 3 Ankyrin repeats (many copies) AAA_28 PF13521.6 KDO16550.1 - 0.058 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 KDO16551.1 - 5.2e-06 27.0 0.0 6.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Metallophos_3 PF14582.6 KDO16551.1 - 0.072 12.4 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PTN13_u3 PF16599.5 KDO16552.1 - 0.26 11.3 0.4 0.37 10.8 0.4 1.1 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ CPP1-like PF11833.8 KDO16553.1 - 0.012 15.3 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HALZ PF02183.18 KDO16554.1 - 0.09 13.0 16.6 0.24 11.7 0.0 4.5 4 1 0 4 4 4 0 Homeobox associated leucine zipper TPR_1 PF00515.28 KDO16555.1 - 2.1e-14 52.6 2.6 5.1e-05 22.9 0.0 3.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16555.1 - 1.2e-10 40.6 2.5 0.0004 20.3 0.6 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO16555.1 - 1.5e-07 31.4 2.5 4.2e-06 26.8 1.3 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO16555.1 - 4.4e-06 26.3 1.3 1.3 9.3 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO16555.1 - 4.4e-06 26.9 1.7 0.00032 20.9 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO16555.1 - 8.2e-06 25.6 0.9 0.025 14.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO16555.1 - 0.00076 19.5 0.6 1.3 9.2 0.0 2.6 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KDO16555.1 - 0.00088 19.9 3.8 3.4 8.7 2.3 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO16555.1 - 0.0049 17.1 0.7 0.76 10.3 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16555.1 - 0.023 15.4 3.3 0.45 11.2 1.5 2.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO16555.1 - 0.05 14.3 2.4 1.8 9.4 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO16555.1 - 0.051 13.3 1.2 13 5.6 0.0 3.3 2 2 1 3 3 3 0 TPR repeat TEBP_beta PF07404.11 KDO16556.1 - 0.035 13.5 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Cadherin-like PF12733.7 KDO16556.1 - 0.11 13.1 0.0 13 6.4 0.0 2.4 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain LRR_6 PF13516.6 KDO16557.1 - 2e-11 43.0 2.4 0.0031 17.4 0.1 4.5 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 KDO16557.1 - 6.1e-07 29.7 0.1 5.8e-05 23.4 0.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO16557.1 - 3.2e-06 26.8 0.1 0.00023 20.9 0.0 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KDO16557.1 - 0.0098 16.3 0.0 31 5.7 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich Repeat BT1 PF03092.16 KDO16558.1 - 9.9e-10 37.2 3.7 1.2e-09 37.0 3.7 1.0 1 0 0 1 1 1 1 BT1 family PUCC PF03209.15 KDO16558.1 - 0.00011 21.4 0.7 0.00016 20.8 0.7 1.2 1 0 0 1 1 1 1 PUCC protein Cation_ATPase_C PF00689.21 KDO16558.1 - 0.021 14.5 2.0 0.028 14.1 2.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Acatn PF13000.7 KDO16558.1 - 0.054 12.0 0.5 0.06 11.8 0.5 1.2 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 p25-alpha PF05517.12 KDO16559.1 - 1.1e-10 41.8 2.3 3.6e-06 27.2 0.0 3.4 2 1 0 2 2 2 2 p25-alpha CH PF00307.31 KDO16559.1 - 0.00022 21.4 0.0 0.00064 19.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KDO16559.1 - 0.011 15.8 0.1 0.052 13.7 0.0 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein RPN13_C PF16550.5 KDO16559.1 - 0.039 14.1 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 UCH-binding domain CAMSAP_CH PF11971.8 KDO16559.1 - 0.075 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain F420_oxidored PF03807.17 KDO16560.1 - 1.5e-08 35.1 0.1 1.9e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent EF1_GNE PF00736.19 KDO16561.1 - 1.4 9.1 6.9 24 5.2 0.2 3.8 2 1 0 2 2 2 0 EF-1 guanine nucleotide exchange domain Type2_restr_D3 PF16902.5 KDO16561.1 - 1.9 8.5 6.3 3.5 7.6 0.2 3.8 4 0 0 4 4 4 0 Type-2 restriction enzyme D3 domain ENTH PF01417.20 KDO16563.1 - 0.069 13.2 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 ENTH domain DUF4203 PF13886.6 KDO16564.1 - 1.1e-46 159.1 29.1 1.1e-46 159.1 29.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Sperm_Ag_HE2 PF05324.13 KDO16564.1 - 0.1 13.0 1.0 0.2 12.1 0.3 1.8 2 0 0 2 2 2 0 Sperm antigen HE2 DUF2142 PF09913.9 KDO16565.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF4203 PF13886.6 KDO16566.1 - 2.5e-12 46.9 20.0 2.5e-12 46.9 20.0 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Glu_syn_central PF04898.14 KDO16566.1 - 0.12 11.8 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Peptidase_C69 PF03577.15 KDO16567.1 - 2e-05 23.7 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 TPR_1 PF00515.28 KDO16568.1 - 6.9e-06 25.7 0.1 0.00018 21.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16568.1 - 1.1e-05 25.1 0.4 0.00044 20.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16568.1 - 0.00013 22.6 0.7 0.00036 21.1 0.5 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Sel1 PF08238.12 KDO16568.1 - 0.075 13.8 0.1 0.31 11.8 0.0 2.0 2 0 0 2 2 2 0 Sel1 repeat TPR_12 PF13424.6 KDO16568.1 - 0.19 12.0 1.6 0.77 10.1 0.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_3 PF05977.13 KDO16569.1 - 0.005 15.3 0.1 0.0094 14.4 0.1 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector Mito_carr PF00153.27 KDO16571.1 - 1.7e-22 79.2 0.1 6e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial carrier protein zf-B_box PF00643.24 KDO16572.1 - 1.9e-07 31.1 25.9 0.00037 20.6 7.7 2.4 2 0 0 2 2 2 2 B-box zinc finger FYVE PF01363.21 KDO16572.1 - 4.1 7.6 27.4 1.8 8.8 11.7 2.8 1 1 1 2 2 2 0 FYVE zinc finger A_thal_3526 PF09713.10 KDO16573.1 - 2.3e-25 88.6 0.3 4e-25 87.8 0.3 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) QLQ PF08880.11 KDO16573.1 - 0.026 14.3 1.5 0.026 14.3 1.5 2.1 3 0 0 3 3 3 0 QLQ LRR_8 PF13855.6 KDO16574.1 - 3.8e-29 100.2 22.4 2.3e-11 43.3 0.2 4.1 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KDO16574.1 - 4.6e-29 100.0 11.3 1.4e-07 31.7 1.4 4.1 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO16574.1 - 3.6e-10 38.9 17.2 1 10.2 0.2 7.8 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.6 KDO16574.1 - 5e-09 35.9 2.7 3.2e-05 23.5 0.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KDO16574.1 - 3.9e-06 26.5 9.2 21 5.5 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_3 PF07725.12 KDO16574.1 - 4 7.4 10.3 33 4.5 0.0 5.7 6 1 0 6 6 6 0 Leucine Rich Repeat Peptidase_C1 PF00112.23 KDO16575.1 - 0.00013 22.2 0.3 0.039 14.0 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease TPR_21 PF09976.9 KDO16575.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Endosulfine PF04667.17 KDO16576.1 - 4.9e-05 23.4 0.2 8.2e-05 22.7 0.2 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Glyco_hydro_18 PF00704.28 KDO16577.1 - 2.5e-11 43.9 0.1 3.1e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EF-hand_7 PF13499.6 KDO16581.1 - 1.8e-31 108.4 12.5 2.1e-10 40.9 0.0 6.4 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 KDO16581.1 - 1.2e-21 74.8 14.6 0.00091 19.0 0.3 8.5 9 0 0 9 9 9 6 EF-hand domain EF-hand_1 PF00036.32 KDO16581.1 - 1.8e-21 74.0 19.3 2.9e-05 23.3 0.0 7.4 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 KDO16581.1 - 2.7e-20 72.0 8.6 3.2e-08 33.3 0.0 7.4 6 2 2 8 8 8 5 EF-hand domain pair EF-hand_5 PF13202.6 KDO16581.1 - 2.9e-12 45.5 19.5 0.01 15.3 0.1 6.2 7 0 0 7 7 7 4 EF hand EF-hand_4 PF12763.7 KDO16581.1 - 0.0012 18.8 0.3 9.4 6.2 0.0 3.6 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KDO16581.1 - 0.0034 17.7 0.3 16 5.9 0.0 4.5 5 0 0 5 5 5 1 EF-hand domain EF-hand_11 PF08976.11 KDO16581.1 - 0.018 15.9 0.0 17 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_9 PF14658.6 KDO16581.1 - 0.086 13.2 4.7 1.3 9.4 0.1 4.0 4 0 0 4 4 4 0 EF-hand domain DUF4611 PF15387.6 KDO16581.1 - 1.4 9.2 7.0 2.1 8.6 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Fumble PF03630.14 KDO16582.1 - 8.1e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Fumble DUF4203 PF13886.6 KDO16584.1 - 0.0001 22.1 26.1 0.00017 21.3 26.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2070 PF09843.9 KDO16584.1 - 9 4.4 11.8 11 4.1 11.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PI3_PI4_kinase PF00454.27 KDO16585.1 - 2.2e-72 243.9 0.1 3.4e-72 243.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KDO16585.1 - 5.7e-45 151.8 0.1 1.3e-44 150.6 0.1 1.7 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FAT PF02259.23 KDO16585.1 - 1e-26 94.0 0.1 1.6e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 FAT domain IL11 PF07400.11 KDO16585.1 - 0.08 12.6 0.7 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Interleukin 11 Toprim PF01751.22 KDO16586.1 - 1.9e-15 56.9 0.0 2.2e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Toprim domain p450 PF00067.22 KDO16587.1 - 2e-18 66.4 0.0 7.8e-17 61.2 0.0 2.7 2 1 1 3 3 3 2 Cytochrome P450 Ribosomal_L20 PF00453.18 KDO16588.1 - 2.7e-37 127.1 0.7 3e-37 127.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 SMC_ScpA PF02616.14 KDO16588.1 - 0.036 14.0 0.2 0.042 13.8 0.2 1.1 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Syntaxin_2 PF14523.6 KDO16589.1 - 1 9.8 13.0 4.2 7.8 10.6 2.7 1 1 1 2 2 2 0 Syntaxin-like protein LRR_6 PF13516.6 KDO16592.1 - 0.024 14.7 1.7 42 4.6 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 KDO16592.1 - 0.047 14.1 0.6 4.7 7.8 0.0 2.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) PX PF00787.24 KDO16593.1 - 5.9e-10 39.1 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF2205 PF10224.9 KDO16593.1 - 6.6e-06 26.0 1.0 0.00026 20.9 1.0 2.3 2 0 0 2 2 2 1 Short coiled-coil protein Cob_adeno_trans PF01923.18 KDO16593.1 - 0.0043 17.2 0.3 0.0043 17.2 0.3 1.8 2 0 0 2 2 2 1 Cobalamin adenosyltransferase RRN3 PF05327.11 KDO16593.1 - 0.0063 15.1 2.6 0.0075 14.9 2.6 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_r1_1 PF03979.14 KDO16593.1 - 3.4 7.8 16.0 0.12 12.4 7.9 2.5 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 SQHop_cyclase_C PF13243.6 KDO16595.1 - 2.1e-49 168.4 1.3 2.8e-49 168.0 1.3 1.2 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KDO16595.1 - 4.5e-22 77.5 8.4 1.2e-07 31.4 0.0 5.0 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KDO16595.1 - 3.8e-07 29.5 2.7 0.17 10.9 0.0 4.8 4 2 2 6 6 6 4 Squalene-hopene cyclase N-terminal domain Pec_lyase PF09492.10 KDO16595.1 - 0.00011 21.7 0.1 0.83 8.9 0.0 3.9 3 1 0 4 4 4 2 Pectic acid lyase TED_complement PF07678.14 KDO16595.1 - 0.00017 20.7 0.0 0.21 10.6 0.0 3.6 2 1 0 3 3 3 2 A-macroglobulin TED domain zf-PARP PF00645.18 KDO16596.1 - 1.8e-06 28.7 0.7 1.3e-05 26.0 0.7 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RecA_dep_nuc PF16786.5 KDO16596.1 - 0.047 13.8 0.3 0.056 13.6 0.3 1.1 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease zf-PARP PF00645.18 KDO16597.1 - 2.5e-09 37.9 1.4 1.2e-08 35.7 1.4 1.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MatE PF01554.18 KDO16599.1 - 3.1e-38 131.0 30.9 4.5e-22 78.4 10.1 2.3 2 0 0 2 2 2 2 MatE Adeno_E3_CR2 PF02439.15 KDO16599.1 - 0.66 9.8 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Thioredoxin PF00085.20 KDO16601.1 - 1.2e-10 41.2 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO16601.1 - 0.0072 16.8 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KDO16601.1 - 0.0093 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KDO16601.1 - 0.031 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KDO16601.1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin MCU PF04678.13 KDO16603.1 - 5.2e-29 101.6 1.3 6.3e-29 101.3 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter FragX_IP PF05994.11 KDO16605.1 - 3.3e-95 319.9 0.0 1.9e-74 251.2 0.0 2.4 1 1 1 2 2 2 2 Cytoplasmic Fragile-X interacting family Tubulin PF00091.25 KDO16606.1 - 1.7e-08 34.9 0.0 1.9e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF1168 PF06658.12 KDO16607.1 - 0.056 13.2 13.2 0.081 12.7 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2315 PF10231.9 KDO16607.1 - 0.23 11.6 8.6 0.44 10.7 7.9 1.7 1 1 1 2 2 2 0 Apoptogenic protein 1 Serinc PF03348.15 KDO16608.1 - 4e-57 194.1 3.1 4.6e-57 193.9 3.1 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Big_3_4 PF13754.6 KDO16610.1 - 0.088 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function PBP_N PF17093.5 KDO16611.1 - 0.029 14.6 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus HA PF03457.14 KDO16613.1 - 0.085 13.2 0.2 0.72 10.2 0.0 2.3 3 0 0 3 3 3 0 Helicase associated domain BTB_2 PF02214.22 KDO16614.1 - 7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KDO16616.1 - 7.9e-05 22.9 0.0 0.00019 21.7 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KDO16616.1 - 0.00036 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MIR PF02815.19 KDO16617.1 - 1.5e-11 44.5 0.1 5.8e-06 26.3 0.0 3.9 2 1 2 4 4 4 3 MIR domain Ins145_P3_rec PF08709.11 KDO16617.1 - 4.7e-11 42.3 0.3 2.4e-10 40.0 0.1 2.2 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.6 KDO16617.1 - 0.0014 19.3 0.0 0.12 13.1 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF4272 PF14094.6 KDO16619.1 - 0.0092 15.2 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4272) LEDGF PF11467.8 KDO16619.1 - 0.24 11.0 0.1 0.88 9.2 0.0 1.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) LRR_6 PF13516.6 KDO16619.1 - 2.1 8.6 9.2 26 5.2 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Asn_synthase PF00733.21 KDO16620.1 - 8.5e-15 55.3 0.0 1.2e-14 54.8 0.0 1.3 1 1 0 1 1 1 1 Asparagine synthase Pox_MCEL PF03291.16 KDO16621.1 - 9.2e-09 34.8 0.0 3e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme AAA_25 PF13481.6 KDO16623.1 - 0.13 11.8 0.1 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Mnd1 PF03962.15 KDO16624.1 - 1.3e-24 86.2 0.1 3.2e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KDO16624.1 - 4.9e-18 65.0 0.8 4.9e-18 65.0 0.8 2.0 3 0 0 3 3 1 1 Leucine zipper with capping helix domain RPW8 PF05659.11 KDO16624.1 - 0.0026 17.5 0.8 0.005 16.5 0.8 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 THOC7 PF05615.13 KDO16624.1 - 0.0034 17.7 5.0 0.0049 17.1 5.0 1.4 1 1 0 1 1 1 1 Tho complex subunit 7 Spc7 PF08317.11 KDO16624.1 - 0.023 13.6 9.0 0.26 10.1 9.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_F PF12259.8 KDO16624.1 - 0.036 12.6 1.2 0.042 12.4 1.2 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF4407 PF14362.6 KDO16624.1 - 0.045 13.1 3.4 0.056 12.8 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KDO16624.1 - 0.052 12.1 6.8 0.07 11.7 6.8 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF812 PF05667.11 KDO16624.1 - 0.054 12.4 6.1 0.074 11.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 KDO16624.1 - 0.075 12.4 10.4 0.13 11.6 10.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Val_tRNA-synt_C PF10458.9 KDO16624.1 - 0.28 11.5 5.8 0.36 11.2 0.1 3.0 2 1 2 4 4 3 0 Valyl tRNA synthetase tRNA binding arm APG6_N PF17675.1 KDO16624.1 - 0.35 11.4 10.9 0.66 10.5 10.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KDO16624.1 - 0.39 10.8 12.4 1.1 9.3 12.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KDO16624.1 - 0.57 10.7 11.6 1.4 9.4 1.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-K PF11802.8 KDO16624.1 - 0.71 9.4 9.3 1.7 8.2 9.3 1.6 1 1 0 1 1 1 0 Centromere-associated protein K Viral_P18 PF04521.13 KDO16624.1 - 0.94 9.3 4.8 0.44 10.3 0.5 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DHR10 PF18595.1 KDO16624.1 - 1.3 9.1 16.8 1 9.5 13.3 2.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain PilO PF04350.13 KDO16624.1 - 2.3 8.4 8.2 0.6 10.2 3.8 2.2 2 1 1 3 3 3 0 Pilus assembly protein, PilO DegS PF05384.11 KDO16624.1 - 5.7 6.4 11.0 3 7.3 5.5 2.5 2 1 0 2 2 2 0 Sensor protein DegS DivIC PF04977.15 KDO16624.1 - 9.2 6.1 13.0 13 5.6 4.6 2.8 1 1 1 2 2 2 0 Septum formation initiator Ank_2 PF12796.7 KDO16625.1 - 1.3e-66 221.1 29.3 1e-15 58.0 0.1 4.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16625.1 - 5.2e-35 119.4 9.2 7.4e-09 36.0 0.1 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16625.1 - 8.1e-30 99.5 14.1 0.00093 19.5 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KDO16625.1 - 6.2e-21 74.2 20.0 1e-06 28.9 0.6 7.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO16625.1 - 1.8e-16 59.7 28.6 0.0019 18.6 0.1 8.8 8 1 0 8 8 8 6 Ankyrin repeat DUF1764 PF08576.10 KDO16626.1 - 6.7e-22 78.3 2.3 6.7e-22 78.3 2.3 2.1 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Dynactin_p62 PF05502.13 KDO16626.1 - 0.039 12.7 6.4 0.045 12.5 6.4 1.0 1 0 0 1 1 1 0 Dynactin p62 family Tli4_N PF18443.1 KDO16626.1 - 0.2 12.0 3.3 0.16 12.4 0.3 2.0 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain PDCD2_C PF04194.13 KDO16626.1 - 0.31 11.1 11.9 3.5 7.7 11.9 2.0 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain PA26 PF04636.13 KDO16626.1 - 1.4 7.8 5.2 1.5 7.6 5.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spt5_N PF11942.8 KDO16626.1 - 2.4 9.2 14.0 1.3 10.1 11.2 1.8 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Alpha-2-MRAP_N PF06400.11 KDO16626.1 - 10 6.2 14.6 63 3.6 14.6 1.9 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain Dynein_C PF18199.1 KDO16627.1 - 9.9e-08 31.6 0.0 6.4e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain C-terminal domain Mog1 PF04603.12 KDO16628.1 - 1.7e-36 125.6 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NIF PF03031.18 KDO16630.1 - 3.3e-13 49.7 0.1 3.9e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Astacin PF01400.24 KDO16632.1 - 1.7e-14 53.9 0.4 1.2e-12 47.8 0.4 2.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Geminin PF07412.12 KDO16633.1 - 0.076 12.8 0.7 0.076 12.8 0.7 1.7 1 1 1 2 2 2 0 Geminin SlyX PF04102.12 KDO16633.1 - 0.15 12.7 6.0 1.3 9.7 1.5 2.4 2 1 0 2 2 2 0 SlyX SDA1 PF05285.12 KDO16634.1 - 1.2 8.5 13.8 1.1 8.6 13.8 1.1 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 KDO16634.1 - 1.3 8.9 22.3 1.5 8.7 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KDO16634.1 - 3.2 5.8 13.1 2.9 6.0 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2076 PF09849.9 KDO16634.1 - 5.5 6.9 11.3 6 6.8 11.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PARG_cat PF05028.14 KDO16635.1 - 0.35 10.1 2.8 9.6 5.4 0.1 2.0 2 0 0 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) ARL17 PF15840.5 KDO16635.1 - 0.59 10.5 12.2 2.9 8.3 0.3 3.4 2 1 1 3 3 3 0 ADP-ribosylation factor-like protein 17 Ion_trans PF00520.31 KDO16636.1 - 1.4e-55 188.2 31.8 3.9e-35 121.2 13.6 2.1 2 0 0 2 2 2 2 Ion transport protein DUF4834 PF16118.5 KDO16636.1 - 0.0064 17.4 0.9 0.94 10.5 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) Lustrin_cystein PF14625.6 KDO16636.1 - 0.028 14.8 0.9 0.053 13.9 0.9 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Neur_chan_memb PF02932.16 KDO16636.1 - 0.079 13.0 0.3 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tir_receptor_N PF07490.11 KDO16636.1 - 0.18 11.6 1.4 15 5.3 0.0 2.2 1 1 1 2 2 2 0 Translocated intimin receptor (Tir) N-terminus OppC_N PF12911.7 KDO16636.1 - 0.39 10.7 15.0 6.5 6.8 0.4 4.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C TFIIE-A_C PF11521.8 KDO16636.1 - 0.7 10.2 1.9 1.3 9.4 0.4 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha BDHCT_assoc PF16204.5 KDO16636.1 - 1.9 8.2 5.3 0.29 10.8 1.1 1.7 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein HemY_N PF07219.13 KDO16636.1 - 3.8 7.7 6.0 9.6 6.5 0.0 3.4 3 0 0 3 3 3 0 HemY protein N-terminus Kinesin PF00225.23 KDO16637.1 - 2.9e-27 95.5 0.9 3e-22 79.0 0.1 2.0 1 1 1 2 2 2 2 Kinesin motor domain DnaJ_C PF01556.18 KDO16638.1 - 1.3e-39 135.7 0.4 1.5e-39 135.4 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KDO16638.1 - 1.2e-14 54.4 19.3 1.2e-14 54.4 19.3 1.8 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.19 KDO16638.1 - 0.013 15.5 6.8 0.95 9.5 0.1 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KDO16638.1 - 1.1 9.4 7.7 2.4 8.3 1.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF2614 PF11023.8 KDO16638.1 - 1.1 9.3 4.0 0.33 11.1 0.7 1.7 1 1 0 2 2 2 0 Zinc-ribbon containing domain zf-RING_10 PF16685.5 KDO16638.1 - 5 7.3 9.5 6.6 6.9 6.9 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 ATP-synt_G PF04718.15 KDO16639.1 - 0.13 13.1 0.0 0.16 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit Utp12 PF04003.12 KDO16640.1 - 1.7e-20 73.3 0.3 3.2e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Sigma70_ner PF04546.13 KDO16640.1 - 1.1 9.1 19.4 0.19 11.6 5.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region BUD22 PF09073.10 KDO16640.1 - 1.3 8.3 20.0 0.076 12.3 2.1 2.1 2 0 0 2 2 2 0 BUD22 BTV_NS2 PF04514.12 KDO16640.1 - 2 7.2 18.2 0.19 10.5 3.6 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DNA_pol_phi PF04931.13 KDO16640.1 - 9.3 4.2 32.0 1 7.4 17.5 2.1 2 0 0 2 2 2 0 DNA polymerase phi Chibby PF14645.6 KDO16644.1 - 0.015 15.7 1.2 0.044 14.2 1.2 1.8 1 0 0 1 1 1 0 Chibby family APG6_N PF17675.1 KDO16644.1 - 1.4 9.4 9.7 0.18 12.3 5.0 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region EF-hand_1 PF00036.32 KDO16645.1 - 8.7e-18 62.5 0.4 1.6e-08 33.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO16645.1 - 1e-13 50.0 0.7 1.3e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KDO16645.1 - 4.2e-13 48.1 1.3 3e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO16645.1 - 5.6e-12 45.9 0.1 1.1e-11 45.0 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO16645.1 - 5.6e-07 29.3 1.9 0.003 17.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KDO16645.1 - 0.22 11.5 1.0 11 6.1 0.0 2.2 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_3 PF00933.21 KDO16647.1 - 5e-38 131.2 0.1 6e-38 131.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Exo_endo_phos PF03372.23 KDO16648.1 - 1.6e-07 31.1 1.0 2.1e-07 30.7 1.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family V-set_2 PF15910.5 KDO16649.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 ICOS V-set domain PT PF04886.12 KDO16650.1 - 1.3e-10 40.6 69.2 1.6e-05 24.4 15.5 4.4 2 1 2 4 4 4 4 PT repeat Myosin_N PF02736.19 KDO16653.1 - 2.6e-07 30.4 0.1 3.7e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.21 KDO16653.1 - 6.9e-07 27.9 0.0 7.9e-07 27.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) zf-BED PF02892.15 KDO16655.1 - 0.005 16.8 2.9 0.7 10.0 0.4 2.2 2 0 0 2 2 2 2 BED zinc finger zf_PR_Knuckle PF18445.1 KDO16655.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 PR zinc knuckle motif UQ_con PF00179.26 KDO16656.1 - 4.2e-08 32.9 0.0 4.8e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC2_membrane_3 PF12698.7 KDO16660.1 - 2.9e-14 53.0 6.3 2.9e-14 53.0 6.3 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KDO16660.1 - 0.0073 15.6 5.4 0.0073 15.6 5.4 1.8 3 0 0 3 3 3 1 ABC-2 family transporter protein PspB PF06667.12 KDO16660.1 - 0.01 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B RdRP_4 PF02123.16 KDO16661.1 - 0.073 11.9 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase ATG16 PF08614.11 KDO16665.1 - 0.00023 21.5 4.3 0.00034 20.9 4.3 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 KDO16665.1 - 0.0041 16.9 1.7 0.054 13.2 0.2 2.0 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Com_YlbF PF06133.11 KDO16665.1 - 0.017 15.7 0.4 0.066 13.8 0.2 1.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA TMF_DNA_bd PF12329.8 KDO16665.1 - 0.044 13.8 0.4 0.73 9.9 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Apolipo_F PF15148.6 KDO16665.1 - 0.049 13.1 0.8 0.095 12.2 0.1 1.7 2 0 0 2 2 2 0 Apolipoprotein F Hemerythrin PF01814.23 KDO16665.1 - 0.053 14.1 1.0 1.2 9.8 0.2 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain MbeD_MobD PF04899.12 KDO16665.1 - 0.059 13.5 2.1 0.18 11.9 2.1 1.8 1 1 0 1 1 1 0 MbeD/MobD like SlyX PF04102.12 KDO16665.1 - 0.1 13.2 4.8 4.1 8.1 2.4 2.4 2 1 0 2 2 2 0 SlyX DUF2968 PF11180.8 KDO16665.1 - 0.56 9.8 10.5 1.1 8.9 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) APG6_N PF17675.1 KDO16665.1 - 0.88 10.1 5.2 1.7 9.2 0.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 KDO16666.1 - 0.0062 16.9 0.6 0.0098 16.3 0.6 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 KDO16666.1 - 0.027 14.3 1.0 0.048 13.4 1.0 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 KDO16666.1 - 0.076 13.3 0.5 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper AUX_IAA PF02309.16 KDO16666.1 - 5.3 6.8 7.1 0.75 9.6 2.2 1.8 2 0 0 2 2 2 0 AUX/IAA family Pkinase_Tyr PF07714.17 KDO16667.1 - 1.3e-16 60.7 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO16667.1 - 9.6e-09 35.0 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.15 KDO16667.1 - 0.058 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KDO16667.1 - 0.12 13.2 0.1 0.64 10.9 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KDO16667.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CrgA PF06781.12 KDO16668.1 - 0.015 15.4 0.1 0.052 13.6 0.0 1.7 1 1 1 2 2 2 0 Cell division protein CrgA DUF2811 PF10929.8 KDO16668.1 - 0.046 14.0 0.1 0.066 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Metallophos PF00149.28 KDO16669.1 - 2.6e-09 37.9 0.0 4.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_4 PF13637.6 KDO16670.1 - 1.7e-12 47.6 0.3 1.4e-08 35.1 0.1 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16670.1 - 8e-10 38.1 0.1 0.00079 19.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO16670.1 - 2.3e-08 34.5 0.2 3e-08 34.1 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO16670.1 - 5.9e-07 29.6 1.2 0.0085 16.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO16670.1 - 3.7e-06 27.1 0.4 0.0063 16.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2122 PF09895.9 KDO16670.1 - 0.027 14.8 0.1 0.033 14.6 0.1 1.1 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) cNMP_binding PF00027.29 KDO16671.1 - 4.6e-38 129.2 0.3 1.4e-18 66.7 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DUF5586 PF17824.1 KDO16671.1 - 0.00054 19.2 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) ATP-synt_DE_N PF02823.16 KDO16671.1 - 0.0051 16.7 0.0 4.6 7.2 0.0 2.5 2 0 0 2 2 2 2 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF5044 PF16447.5 KDO16671.1 - 0.011 15.5 0.1 0.33 10.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5044) MAM33 PF02330.16 KDO16671.1 - 0.013 15.5 0.7 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein EF-hand_14 PF17959.1 KDO16671.1 - 0.026 14.9 0.2 7 7.1 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Dpy-30 PF05186.13 KDO16671.1 - 0.15 11.8 0.3 0.83 9.4 0.2 2.3 2 1 0 2 2 2 0 Dpy-30 motif Proteasome PF00227.26 KDO16672.1 - 4.4e-26 91.5 0.2 1.1e-25 90.3 0.2 1.5 1 1 0 1 1 1 1 Proteasome subunit Abhydrolase_6 PF12697.7 KDO16673.1 - 2.6e-12 47.8 2.0 3.4e-12 47.4 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO16673.1 - 1.1e-11 44.8 0.0 1.9e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO16673.1 - 9.5e-09 34.9 0.2 9.1e-08 31.6 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Tup_N PF08581.10 KDO16674.1 - 9.8e-05 22.6 1.5 9.8e-05 22.6 1.5 4.0 2 2 0 3 3 3 1 Tup N-terminal Syntaxin PF00804.25 KDO16674.1 - 0.0041 16.8 5.4 0.0041 16.8 5.4 2.1 1 1 1 2 2 2 1 Syntaxin Med9 PF07544.13 KDO16674.1 - 0.027 14.5 0.5 0.027 14.5 0.5 3.5 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 KDO16674.1 - 0.069 13.6 14.6 9 6.8 0.1 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KDO16674.1 - 0.077 12.8 20.2 0.18 11.6 5.2 3.5 2 2 2 4 4 4 0 Septum formation initiator DUF848 PF05852.11 KDO16674.1 - 0.22 11.6 12.0 0.062 13.4 1.5 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3138 PF11336.8 KDO16674.1 - 0.32 9.6 0.6 0.38 9.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TPR_MLP1_2 PF07926.12 KDO16674.1 - 0.51 10.4 21.8 0.37 10.8 9.1 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HEPN_Cthe2314 PF18730.1 KDO16674.1 - 0.66 10.0 9.0 3.3 7.7 1.6 2.5 1 1 0 2 2 2 0 Cthe_2314-like HEPN WHEP-TRS PF00458.20 KDO16674.1 - 0.76 10.0 8.1 8.7 6.6 7.9 2.6 1 1 0 1 1 1 0 WHEP-TRS domain COG2 PF06148.11 KDO16674.1 - 0.78 9.8 13.9 4.4 7.4 10.9 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC92 PF14916.6 KDO16674.1 - 0.86 9.4 6.4 2.6 7.9 3.0 3.1 2 1 1 3 3 3 0 Coiled-coil domain of unknown function CENP-Q PF13094.6 KDO16674.1 - 1.4 9.1 20.9 4.8 7.3 9.4 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit OrfB_IS605 PF01385.19 KDO16674.1 - 1.6 9.0 11.8 0.043 14.1 1.8 2.6 2 1 1 3 3 3 0 Probable transposase APG6_N PF17675.1 KDO16674.1 - 1.6 9.2 24.9 6 7.4 3.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 KDO16674.1 - 1.8 9.2 11.4 5.9 7.5 0.7 2.9 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Uso1_p115_C PF04871.13 KDO16674.1 - 2.7 8.4 18.8 1.3 9.4 6.7 3.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 KDO16674.1 - 2.8 8.2 6.7 2.9 8.2 4.7 2.3 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 KDO16674.1 - 3.2 8.4 19.0 5.1 7.8 2.0 4.5 1 1 3 4 4 4 0 SlyX BST2 PF16716.5 KDO16674.1 - 3.4 8.3 18.2 2.2 8.9 1.8 3.6 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 YtxH PF12732.7 KDO16674.1 - 3.5 8.2 8.5 5.7e+02 1.1 8.5 3.0 1 1 0 1 1 1 0 YtxH-like protein Fib_alpha PF08702.10 KDO16674.1 - 3.8 7.7 18.4 1.2 9.3 6.7 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KDO16674.1 - 4 7.5 21.7 0.72 9.9 17.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KDO16674.1 - 4.1 5.9 18.9 0.17 10.5 6.5 2.1 1 1 1 2 2 2 0 AAA domain DUF3450 PF11932.8 KDO16674.1 - 4.3 6.6 18.3 3.6 6.8 7.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HrpB2 PF09487.10 KDO16674.1 - 4.7 7.7 7.7 2.4 8.6 0.6 2.7 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) TSNAXIP1_N PF15739.5 KDO16674.1 - 5.2 7.5 19.7 1.7 9.0 1.9 2.9 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus HisKA PF00512.25 KDO16674.1 - 6.5 6.9 9.9 0.97 9.5 0.3 3.4 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain betaPIX_CC PF16523.5 KDO16674.1 - 8.9 6.2 26.4 0.2 11.5 3.6 4.0 2 2 2 4 4 4 0 betaPIX coiled coil PKD_channel PF08016.12 KDO16676.1 - 0.066 11.9 5.8 0.1 11.2 5.8 1.3 1 0 0 1 1 1 0 Polycystin cation channel Ion_trans PF00520.31 KDO16676.1 - 0.14 11.3 11.0 0.18 11.0 11.0 1.2 1 0 0 1 1 1 0 Ion transport protein MFS_1 PF07690.16 KDO16677.1 - 6.2e-07 28.6 15.9 7.7e-07 28.4 15.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_8 PF13181.6 KDO16679.1 - 2e-05 24.4 0.3 0.1 12.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16679.1 - 0.00022 21.1 2.9 0.077 13.1 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO16679.1 - 0.0025 17.5 1.5 0.36 10.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO16679.1 - 0.0032 17.7 0.1 0.046 14.1 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO16679.1 - 0.0073 16.9 0.7 0.18 12.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO16679.1 - 0.034 14.2 0.2 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO16679.1 - 0.3 10.8 2.2 0.4 10.4 0.1 2.2 3 0 0 3 3 3 0 TPR repeat Herpes_glycop PF01528.16 KDO16681.1 - 0.054 12.3 2.4 0.064 12.1 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M FYVE PF01363.21 KDO16683.1 - 1.1e-14 54.3 8.5 2e-14 53.5 8.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger TBCC_N PF16752.5 KDO16683.1 - 0.0088 16.5 0.2 0.017 15.5 0.2 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain FYVE_2 PF02318.16 KDO16683.1 - 0.1 12.8 5.5 0.21 11.8 5.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_2 PF13639.6 KDO16683.1 - 2.8 8.4 12.7 8.6 6.8 12.9 1.8 1 1 0 1 1 1 0 Ring finger domain DUF2256 PF10013.9 KDO16683.1 - 4.9 7.4 8.3 1.7 8.8 3.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KDO16683.1 - 8.1 6.4 9.1 1.5 8.7 4.3 2.1 2 0 0 2 2 2 0 HIT zinc finger SpoU_methylase PF00588.19 KDO16684.1 - 0.0014 18.8 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family PARP PF00644.20 KDO16685.1 - 4.4e-05 23.2 1.0 0.0048 16.5 0.2 2.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Beta-lactamase PF00144.24 KDO16686.1 - 1.9e-38 132.5 5.8 7.1e-38 130.7 5.8 1.7 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO16686.1 - 0.0014 18.2 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase enzyme family Pkinase PF00069.25 KDO16687.1 - 6.4e-36 124.1 0.0 8.1e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16687.1 - 4.5e-34 117.9 0.0 6e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO16687.1 - 0.024 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thiolase_C PF02803.18 KDO16688.1 - 0.078 12.6 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Thiolase, C-terminal domain Syntaxin-6_N PF09177.11 KDO16689.1 - 0.0019 18.7 0.8 0.002 18.7 0.8 1.1 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 KDO16689.1 - 0.0021 18.0 0.9 0.0026 17.7 0.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Nsp1_C PF05064.13 KDO16689.1 - 0.0038 17.0 0.6 0.0042 16.9 0.6 1.0 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF5086 PF16985.5 KDO16689.1 - 0.05 13.5 0.2 0.056 13.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) DHR10 PF18595.1 KDO16689.1 - 0.055 13.5 6.8 0.085 12.9 6.8 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Spc24 PF08286.11 KDO16689.1 - 0.065 13.5 0.9 0.075 13.3 0.9 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Globin PF00042.22 KDO16690.1 - 0.054 14.1 0.5 0.79 10.3 0.5 2.2 1 1 0 1 1 1 0 Globin CBM_1 PF00734.18 KDO16692.1 - 3.1e-11 43.0 7.3 6.5e-11 42.0 7.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO16692.1 - 1.4e-08 34.2 63.7 0.0025 17.3 15.1 3.6 1 1 1 2 2 2 1 PT repeat CDC27 PF09507.10 KDO16692.1 - 5.3 6.3 14.8 5.5 6.3 14.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NFACT-C PF11923.8 KDO16694.1 - 2.8e-32 110.8 0.2 6.8e-32 109.6 0.0 1.7 2 0 0 2 2 2 1 NFACT protein C-terminal domain MetJ PF01340.20 KDO16694.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Met Apo-repressor, MetJ OTU PF02338.19 KDO16695.1 - 2.6e-23 82.9 2.3 3.6e-23 82.4 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KDO16695.1 - 6.8e-06 25.7 1.2 0.00062 19.3 0.0 2.7 3 1 0 3 3 3 2 Peptidase C65 Otubain FlgI PF02119.16 KDO16695.1 - 0.046 12.7 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar P-ring protein Golgin_A5 PF09787.9 KDO16695.1 - 0.26 10.7 14.2 0.043 13.3 6.6 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Beta-APP PF03494.13 KDO16696.1 - 0.23 11.4 0.0 0.51 10.2 0.0 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Ank_4 PF13637.6 KDO16698.1 - 1.8e-07 31.6 0.3 0.0046 17.5 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO16698.1 - 4.4e-06 27.2 0.1 7.6e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO16698.1 - 1.2e-05 25.5 0.3 0.2 12.1 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO16698.1 - 0.087 13.3 0.1 13 6.4 0.1 3.1 1 1 0 1 1 1 0 Ankyrin repeat CENP-F_leu_zip PF10473.9 KDO16699.1 - 0.00013 22.0 2.3 0.00013 22.0 2.3 2.6 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KDO16699.1 - 0.0026 15.4 23.4 0.0031 15.1 23.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CEP209_CC5 PF16574.5 KDO16699.1 - 0.0031 17.7 0.5 0.0031 17.7 0.5 2.4 1 1 1 2 2 2 1 Coiled-coil region of centrosome protein CE290 SHE3 PF17078.5 KDO16699.1 - 0.018 14.8 9.0 0.058 13.1 9.0 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 SlyX PF04102.12 KDO16699.1 - 0.023 15.3 1.6 0.023 15.3 1.6 3.7 1 1 3 4 4 4 0 SlyX AATase PF07247.12 KDO16699.1 - 0.098 11.2 0.1 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 Alcohol acetyltransferase Macoilin PF09726.9 KDO16699.1 - 0.1 11.2 16.5 0.16 10.5 16.5 1.3 1 1 0 1 1 1 0 Macoilin family FlaC_arch PF05377.11 KDO16699.1 - 0.12 12.8 0.5 1.4 9.3 0.0 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 KDO16699.1 - 0.34 10.7 11.0 0.24 11.2 7.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 KDO16699.1 - 0.38 11.3 2.5 3 8.4 2.5 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RNA_lig_T4_1 PF09511.10 KDO16699.1 - 0.56 10.0 6.7 0.97 9.2 6.7 1.5 1 1 0 1 1 1 0 RNA ligase DUF3450 PF11932.8 KDO16699.1 - 0.66 9.2 15.5 0.87 8.8 15.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KDO16699.1 - 1.3 9.6 5.5 2.1 8.9 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fez1 PF06818.15 KDO16699.1 - 1.6 9.1 15.3 2 8.8 14.4 1.5 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.12 KDO16699.1 - 2.2 8.3 8.7 4.2 7.4 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KDO16699.1 - 2.3 8.2 7.7 9.1 6.2 0.0 3.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase THOC7 PF05615.13 KDO16699.1 - 2.9 8.2 21.1 0.32 11.3 10.1 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 ADIP PF11559.8 KDO16699.1 - 3.9 7.5 18.5 13 5.8 12.0 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 KDO16699.1 - 4.7 5.7 11.8 0.41 9.2 2.9 2.0 1 1 1 2 2 2 0 AAA domain DUF724 PF05266.14 KDO16699.1 - 7.5 6.3 14.6 6.8 6.5 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) NAD_binding_6 PF08030.12 KDO16700.1 - 4.6e-12 46.3 0.0 1.2e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KDO16700.1 - 1.5e-08 35.3 0.0 2.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KDO16700.1 - 1.4e-07 31.5 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Acyltransferase PF01553.21 KDO16702.1 - 1.4e-08 34.4 0.0 3.2e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase CENP-H PF05837.12 KDO16703.1 - 0.15 12.5 14.1 0.33 11.4 14.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CENP-K PF11802.8 KDO16703.1 - 0.31 10.6 12.5 0.37 10.3 12.5 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Band_3_cyto PF07565.13 KDO16703.1 - 0.56 10.0 9.2 0.69 9.7 9.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3450 PF11932.8 KDO16703.1 - 0.67 9.2 22.7 0.92 8.8 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_23 PF13476.6 KDO16703.1 - 0.78 10.2 9.5 1 9.8 9.5 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 KDO16703.1 - 1.5 8.6 10.8 1.8 8.3 10.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 KDO16703.1 - 1.8 8.5 8.6 2.5 8.1 8.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CSRNP_N PF16019.5 KDO16703.1 - 2.1 8.2 9.1 2.7 7.9 9.1 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4407 PF14362.6 KDO16703.1 - 3.9 6.7 16.5 4.7 6.5 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Folliculin PF11704.8 KDO16703.1 - 4.4 7.2 9.7 5.6 6.8 9.7 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 KDO16703.1 - 4.9 5.8 9.4 5.5 5.7 9.4 1.1 1 0 0 1 1 1 0 Presenilin DUF737 PF05300.11 KDO16703.1 - 6.6 7.0 19.7 10 6.4 19.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Sec62 PF03839.16 KDO16703.1 - 6.8 6.1 9.9 7.8 5.9 9.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TMPIT PF07851.13 KDO16703.1 - 8 5.6 9.1 8.2 5.6 9.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1699 PF08004.11 KDO16704.1 - 0.021 14.5 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) DUF4181 PF13789.6 KDO16707.1 - 1.4 9.3 6.3 0.27 11.5 1.7 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) PAM2 PF07145.15 KDO16709.1 - 0.0055 16.3 0.0 0.0055 16.3 0.0 1.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Pex14_N PF04695.13 KDO16709.1 - 0.015 16.0 3.5 0.015 16.0 3.5 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Amidohydro_1 PF01979.20 KDO16710.1 - 2.5e-31 109.2 0.1 2.9e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KDO16710.1 - 3.3e-10 40.1 0.0 3.4e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family MORN PF02493.20 KDO16711.1 - 2.1e-77 250.6 97.8 2.2e-07 30.4 0.7 17.6 17 0 0 17 17 17 16 MORN repeat IQ PF00612.27 KDO16711.1 - 0.0016 18.1 2.9 1.5 8.8 0.9 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif FOXP-CC PF16159.5 KDO16711.1 - 7.4 7.3 8.2 15 6.3 4.0 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain Dimer_Tnp_hAT PF05699.14 KDO16712.1 - 0.0043 16.8 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1455 PF07306.11 KDO16712.1 - 0.052 13.5 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) Metallophos PF00149.28 KDO16713.1 - 7.9e-15 55.9 0.0 1.4e-14 55.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO16713.1 - 5.3e-05 23.5 0.0 0.00054 20.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WHH PF14414.6 KDO16713.1 - 0.081 12.8 0.6 0.19 11.6 0.6 1.5 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH UDG PF03167.19 KDO16713.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily PPR_long PF17177.4 KDO16715.1 - 0.014 14.7 8.6 0.86 8.9 0.5 4.3 2 2 3 5 5 5 0 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KDO16716.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.6 2 0 0 2 2 2 0 PPR repeat family Myb_DNA-binding PF00249.31 KDO16720.1 - 8.4e-11 41.9 7.9 1.3e-06 28.4 1.1 3.1 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO16720.1 - 2.4e-10 40.5 1.3 2.9e-05 24.2 0.0 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain CRS1_YhbY PF01985.21 KDO16720.1 - 0.074 13.2 0.3 2.6 8.3 0.1 2.2 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain Kelch_4 PF13418.6 KDO16721.1 - 4.3e-13 49.0 0.0 3.4e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KDO16721.1 - 1.5e-11 44.2 0.0 1e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO16721.1 - 2.6e-07 30.7 0.1 0.00025 21.2 0.1 2.3 2 1 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 KDO16721.1 - 8.6e-06 25.6 0.6 0.065 13.2 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KDO16721.1 - 2.7e-05 23.9 1.9 6.7e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 KDO16721.1 - 0.00032 20.2 1.2 0.0065 16.0 0.1 2.6 3 1 0 3 3 3 1 Kelch motif Trypsin_2 PF13365.6 KDO16723.1 - 8.3e-20 72.2 0.0 1.5e-19 71.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KDO16723.1 - 0.0017 17.1 0.7 0.14 10.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 DUF4649 PF15507.6 KDO16723.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) NifU PF01106.17 KDO16723.1 - 0.31 11.2 1.8 1.4 9.1 0.2 2.7 3 0 0 3 3 3 0 NifU-like domain PPC PF04151.15 KDO16723.1 - 3.1 9.0 6.0 0.53 11.4 0.6 2.5 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Disintegrin PF00200.23 KDO16724.1 - 1.3e-39 134.9 189.4 4.4e-06 27.4 2.3 15.0 10 5 2 12 12 12 10 Disintegrin MatE PF01554.18 KDO16725.1 - 1.5e-28 99.5 20.6 7.1e-28 97.3 11.2 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO16725.1 - 6.3e-05 23.1 3.2 6.3e-05 23.1 3.2 3.5 1 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain CcmB PF03379.13 KDO16725.1 - 0.019 14.5 1.4 0.019 14.5 1.4 2.5 2 1 1 3 3 3 0 CcmB protein CSG2 PF16965.5 KDO16726.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DHHC PF01529.20 KDO16730.1 - 4.6e-24 85.0 14.5 5.8e-22 78.2 14.5 2.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF2177 PF09945.9 KDO16730.1 - 2.5 8.2 8.2 0.15 12.2 1.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) LRR_8 PF13855.6 KDO16731.1 - 2.7e-16 59.1 20.8 5.9e-10 38.8 4.0 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO16731.1 - 1.9e-11 44.0 6.2 2.7e-06 27.6 2.7 2.7 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO16731.1 - 1.5e-10 40.3 8.5 0.02 14.9 0.4 4.6 3 1 1 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KDO16731.1 - 1.7e-07 30.8 3.1 1.2 10.0 0.1 4.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 KDO16731.1 - 0.0058 16.1 0.1 0.0091 15.5 0.1 1.4 1 1 0 1 1 1 1 Leucine-rich repeat Nucleoside_tran PF01733.18 KDO16733.1 - 4.1e-17 62.5 6.1 4.1e-17 62.5 6.1 2.5 2 1 1 3 3 3 2 Nucleoside transporter DUF2198 PF09964.9 KDO16733.1 - 4.9 7.3 9.3 3.4 7.8 1.8 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) Lactamase_B PF00753.27 KDO16734.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF996 PF06195.13 KDO16736.1 - 0.025 14.9 0.2 0.034 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF4064 PF13273.6 KDO16736.1 - 0.043 14.1 0.3 0.061 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2070 PF09843.9 KDO16736.1 - 0.049 11.9 2.2 0.055 11.8 2.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Elicitin PF00964.17 KDO16736.1 - 0.1 12.7 1.0 0.16 12.0 1.0 1.3 1 0 0 1 1 1 0 Elicitin GTP_EFTU PF00009.27 KDO16737.1 - 1.6e-34 119.1 2.5 3e-32 111.7 2.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO16737.1 - 1.6e-09 37.8 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KDO16737.1 - 1.1e-07 31.6 1.7 3e-07 30.1 0.1 2.7 4 0 0 4 4 4 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KDO16737.1 - 2.3e-06 27.6 1.4 0.00062 19.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 KDO16737.1 - 3.1e-05 23.5 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 KDO16737.1 - 3.9e-05 23.4 0.0 7.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KDO16737.1 - 0.0062 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KDO16737.1 - 0.0063 16.1 0.1 0.019 14.5 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 KDO16737.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Ras family ATP_bind_1 PF03029.17 KDO16737.1 - 0.012 15.4 0.1 0.14 11.9 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 KDO16737.1 - 0.012 14.6 1.1 0.025 13.6 0.7 1.7 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 KDO16737.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KDO16737.1 - 0.032 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_ATPase PF09818.9 KDO16737.1 - 0.065 12.0 0.0 2 7.1 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 KDO16737.1 - 0.082 13.4 0.2 0.78 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KDO16737.1 - 0.18 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3464 PF11947.8 KDO16738.1 - 4.8 6.9 4.6 2.1 8.1 2.7 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Mlo PF03094.15 KDO16739.1 - 2.4e-06 26.2 0.9 2.6e-06 26.1 0.9 1.0 1 0 0 1 1 1 1 Mlo family Zip PF02535.22 KDO16739.1 - 0.059 12.6 0.5 0.058 12.6 0.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_19 PF14559.6 KDO16740.1 - 6.8e-19 68.2 17.5 2.3e-08 34.4 1.7 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO16740.1 - 4.2e-12 45.8 11.5 0.00012 22.6 0.2 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16740.1 - 1.6e-11 43.4 21.5 8.7e-05 22.3 0.5 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO16740.1 - 5.5e-10 38.6 19.7 6.5e-05 22.6 0.6 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16740.1 - 3.6e-09 37.1 13.5 4e-05 24.2 0.4 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO16740.1 - 5.8e-09 36.0 7.0 0.0061 16.7 1.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO16740.1 - 3.4e-07 30.5 10.9 0.00079 19.7 1.6 4.4 3 2 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO16740.1 - 1e-06 28.9 13.8 0.00017 21.8 1.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KDO16740.1 - 2.7e-06 27.2 16.6 0.0075 16.4 0.3 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO16740.1 - 2.2e-05 24.2 9.5 0.0062 16.4 0.5 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KDO16740.1 - 0.00054 19.6 0.6 0.0014 18.2 0.4 2.0 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 KDO16740.1 - 0.00062 19.8 5.1 1.1 9.3 0.0 3.6 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 KDO16740.1 - 0.00096 18.6 6.9 0.0036 16.7 0.2 2.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 KDO16740.1 - 0.0023 17.6 17.7 0.046 13.4 1.3 6.4 5 2 2 7 7 7 2 TPR repeat YfiO PF13525.6 KDO16740.1 - 0.0036 17.1 7.9 0.021 14.6 0.5 2.6 3 0 0 3 3 3 2 Outer membrane lipoprotein TPR_6 PF13174.6 KDO16740.1 - 0.0053 17.3 0.8 0.0053 17.3 0.8 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO16740.1 - 0.035 14.1 13.7 3.7 7.8 0.6 5.5 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO16740.1 - 0.036 14.5 10.0 1.9 9.0 0.3 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Amidase02_C PF12123.8 KDO16740.1 - 0.25 11.1 1.4 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF2989 PF11207.8 KDO16740.1 - 0.48 10.1 4.8 2 8.1 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2989) MIT PF04212.18 KDO16740.1 - 2.7 8.1 5.2 33 4.7 0.1 3.8 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain CBM_1 PF00734.18 KDO16744.1 - 1.2e-05 25.2 11.2 1.2e-05 25.2 11.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain CHCH PF06747.13 KDO16744.1 - 0.026 14.7 4.0 0.21 11.8 0.3 2.3 2 0 0 2 2 2 0 CHCH domain Aldedh PF00171.22 KDO16745.1 - 1.2e-71 241.6 0.1 1.4e-71 241.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1350 PF07082.11 KDO16745.1 - 0.062 12.6 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Mg_trans_NIPA PF05653.14 KDO16746.1 - 3.3e-34 118.3 19.0 1.6e-33 116.1 19.0 1.8 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KDO16746.1 - 1.9e-05 24.9 4.3 1.9e-05 24.9 4.3 3.1 2 1 1 3 3 3 2 EamA-like transporter family DUF3392 PF11872.8 KDO16746.1 - 0.011 16.0 0.9 0.011 16.0 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) DMT_6 PF04342.12 KDO16746.1 - 0.035 14.3 0.7 0.035 14.3 0.7 2.9 3 1 0 3 3 3 0 Putative member of DMT superfamily (DUF486) DUF373 PF04123.13 KDO16746.1 - 0.74 9.2 15.3 0.48 9.8 11.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) TMEM234 PF10639.9 KDO16746.1 - 1.2 9.1 7.8 0.35 10.9 0.3 2.9 3 1 0 3 3 3 0 Putative transmembrane family 234 Tmemb_55A PF09788.9 KDO16746.1 - 3.6 6.6 5.9 1.6 7.7 0.4 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A CLP1_P PF16575.5 KDO16747.1 - 6.2e-53 179.4 0.0 8.8e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KDO16747.1 - 5.7e-24 84.8 0.1 8.8e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLASP_N PF12348.8 KDO16748.1 - 1.8e-07 31.0 0.2 2.6e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KDO16748.1 - 0.2 12.0 2.1 22 5.7 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat Ricin_B_lectin PF00652.22 KDO16749.1 - 5.8e-25 88.0 9.0 6e-08 33.0 0.1 3.7 3 1 0 3 3 3 3 Ricin-type beta-trefoil lectin domain PAN_4 PF14295.6 KDO16749.1 - 3.7e-09 36.3 6.7 1.3e-08 34.6 6.7 2.1 1 0 0 1 1 1 1 PAN domain RicinB_lectin_2 PF14200.6 KDO16749.1 - 2.2e-06 28.3 9.2 0.28 11.9 0.1 4.8 2 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Trypan_PARP PF05887.11 KDO16749.1 - 0.00058 19.9 19.8 0.092 12.7 14.6 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) PAN_1 PF00024.26 KDO16749.1 - 0.0067 16.4 0.2 0.031 14.2 0.2 2.3 1 0 0 1 1 1 1 PAN domain TonB_N PF16031.5 KDO16749.1 - 0.68 10.4 38.0 3.3 8.2 4.5 2.7 2 0 0 2 2 2 0 TonB polyproline region Cellulase PF00150.18 KDO16750.1 - 3.1e-05 23.6 1.4 3.4e-05 23.4 1.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Treacle PF03546.14 KDO16751.1 - 0.22 10.3 0.3 0.32 9.8 0.3 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DUF2457 PF10446.9 KDO16751.1 - 0.63 9.1 4.9 0.94 8.6 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_C1 PF00112.23 KDO16755.1 - 0.00014 22.1 0.1 0.00018 21.7 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease bZIP_1 PF00170.21 KDO16756.1 - 0.011 15.8 1.8 0.015 15.4 1.8 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KDO16756.1 - 0.014 15.4 1.8 0.022 14.8 1.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DASH_Hsk3 PF08227.11 KDO16756.1 - 0.034 14.5 0.7 0.066 13.6 0.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like HrpB7 PF09486.10 KDO16756.1 - 0.038 14.4 0.1 0.053 13.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) MCC-bdg_PDZ PF10506.9 KDO16756.1 - 0.044 13.8 0.1 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TRAF_BIRC3_bd PF16673.5 KDO16756.1 - 0.17 11.7 0.8 0.26 11.1 0.8 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain FAIM1 PF06905.13 KDO16757.1 - 0.062 13.0 0.1 0.084 12.6 0.1 1.1 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) UBA PF00627.31 KDO16759.1 - 1.1e-12 47.5 0.8 1.8e-12 46.9 0.8 1.3 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 KDO16759.1 - 0.00052 19.7 0.0 0.0009 18.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KDO16759.1 - 0.0043 16.8 1.2 0.0074 16.1 1.2 1.4 1 0 0 1 1 1 1 UBA-like domain RuvA_C PF07499.13 KDO16759.1 - 0.056 13.9 0.4 0.091 13.2 0.4 1.3 1 0 0 1 1 1 0 RuvA, C-terminal domain UBA_3 PF09288.10 KDO16759.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF1154 PF06631.11 KDO16760.1 - 1.9 8.6 6.5 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) DUF4254 PF14063.6 KDO16760.1 - 8.6 6.2 9.9 0.094 12.5 1.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) PA PF02225.22 KDO16761.1 - 1.2e-11 44.4 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 PA domain Ras PF00071.22 KDO16763.1 - 9.4e-43 145.6 0.0 1.1e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO16763.1 - 4.1e-24 85.1 0.0 6.1e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO16763.1 - 9.8e-12 44.7 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO16763.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO16763.1 - 0.097 12.0 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region tRNA-synt_2 PF00152.20 KDO16764.1 - 5.3e-11 42.2 0.0 6.8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GST_C_2 PF13410.6 KDO16764.1 - 0.058 13.4 0.0 0.23 11.5 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Exo70 PF03081.15 KDO16767.1 - 1.2e-40 139.8 0.0 2.2e-40 138.9 0.0 1.5 1 1 0 1 1 1 1 Exo70 exocyst complex subunit COG6 PF06419.11 KDO16767.1 - 3.1e-06 25.7 3.5 7.4e-05 21.2 0.1 2.6 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 Sec34 PF04136.15 KDO16767.1 - 0.00023 21.1 0.2 0.00059 19.7 0.0 1.7 2 0 0 2 2 2 1 Sec34-like family ABC_membrane PF00664.23 KDO16768.1 - 1.9e-40 139.3 15.4 2.4e-40 138.9 15.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO16768.1 - 0.00036 21.1 0.4 0.00062 20.3 0.4 1.4 1 0 0 1 1 1 1 ABC transporter OapA_N PF08525.11 KDO16768.1 - 0.13 12.2 1.4 0.31 11.0 1.4 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif MeaB PF03308.16 KDO16768.1 - 0.14 11.1 0.0 0.33 9.9 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KDO16768.1 - 0.23 11.9 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO16769.1 - 1.6e-07 31.9 0.0 2.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KDO16769.1 - 0.0056 16.1 0.2 0.0071 15.8 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain FKBP_N_2 PF18023.1 KDO16769.1 - 0.028 14.5 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal WD40 PF00400.32 KDO16771.1 - 7.3e-07 29.8 4.8 0.00029 21.6 0.9 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO16771.1 - 0.0095 16.2 0.6 4.7 7.6 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO16771.1 - 0.097 12.5 1.2 3 7.7 0.0 2.7 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DENN PF02141.21 KDO16772.1 - 1.8e-53 181.3 4.5 3.2e-53 180.4 4.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain ArfGap PF01412.18 KDO16772.1 - 1.3e-29 102.7 0.1 2e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf uDENN PF03456.18 KDO16772.1 - 1.8e-14 54.2 0.2 3.9e-14 53.1 0.2 1.6 1 0 0 1 1 1 1 uDENN domain LD_cluster2 PF18163.1 KDO16773.1 - 0.24 10.9 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster2 LRR_6 PF13516.6 KDO16775.1 - 1.7e-20 71.2 29.3 6.7e-05 22.6 0.0 9.1 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 KDO16775.1 - 2.7e-06 27.6 6.8 0.017 15.5 0.0 5.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO16775.1 - 0.0026 18.1 1.6 92 4.2 0.0 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO16775.1 - 0.023 14.5 8.7 47 3.9 0.2 5.9 4 2 0 4 4 4 0 Leucine rich repeat ADH_zinc_N PF00107.26 KDO16777.1 - 1e-09 38.5 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO16777.1 - 1.4e-06 29.4 0.0 3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO16777.1 - 3.2e-05 23.8 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KDO16777.1 - 0.006 15.9 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1664 PF07889.12 KDO16778.1 - 0.011 15.7 11.0 0.22 11.6 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 KDO16778.1 - 0.044 13.5 12.9 0.53 10.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) ADIP PF11559.8 KDO16778.1 - 0.045 13.8 14.5 0.4 10.7 2.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Dad4 PF08650.10 KDO16778.1 - 0.052 13.5 1.2 3.3 7.7 0.2 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad4 Spc42p PF11544.8 KDO16778.1 - 0.072 13.1 7.5 4.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p SCO1-SenC PF02630.14 KDO16778.1 - 0.14 12.1 0.7 0.42 10.5 0.2 1.9 1 1 1 2 2 2 0 SCO1/SenC BLOC1_2 PF10046.9 KDO16778.1 - 0.15 12.4 10.9 1.6 9.1 0.9 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 KDO16778.1 - 0.18 9.7 8.7 0.33 8.9 8.7 1.3 1 1 0 1 1 1 0 Prominin KxDL PF10241.9 KDO16778.1 - 0.19 12.1 11.2 0.56 10.5 1.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 KDO16778.1 - 0.31 11.0 8.7 0.37 10.8 2.9 2.2 1 1 1 2 2 2 0 Laminin Domain II VGCC_beta4Aa_N PF12052.8 KDO16778.1 - 0.55 10.4 3.0 2.7 8.2 0.5 2.7 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal TPR_MLP1_2 PF07926.12 KDO16778.1 - 0.57 10.3 12.0 1.1 9.3 6.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 KDO16778.1 - 0.7 10.2 16.2 0.35 11.2 1.7 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 KDO16778.1 - 0.73 10.0 12.4 8.8 6.5 2.0 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 KDO16778.1 - 1.5 9.2 12.8 10 6.5 13.1 1.9 1 1 0 1 1 1 0 Fez1 PI3K_P85_iSH2 PF16454.5 KDO16778.1 - 1.9 8.0 14.7 0.53 9.9 7.5 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 KDO16778.1 - 6 7.4 12.5 9.6 6.7 12.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 KDO16778.1 - 6.7 5.2 7.3 11 4.5 7.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 KDO16778.1 - 9 6.4 16.2 0.46 10.5 4.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding RINGv PF12906.7 KDO16779.1 - 0.017 15.3 5.4 0.038 14.1 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain PRA1 PF03208.19 KDO16779.1 - 0.19 11.3 6.3 0.96 9.1 0.7 2.1 2 0 0 2 2 2 0 PRA1 family protein Bac_export_2 PF01312.19 KDO16779.1 - 0.31 10.2 4.8 1.8 7.7 0.1 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family RINGv PF12906.7 KDO16780.1 - 0.0053 16.9 0.6 0.0079 16.3 0.6 1.3 1 0 0 1 1 1 1 RING-variant domain PHD_4 PF16866.5 KDO16780.1 - 0.012 15.7 0.7 0.016 15.3 0.7 1.3 1 0 0 1 1 1 0 PHD-finger TMEM144 PF07857.12 KDO16781.1 - 1.2e-29 103.3 0.3 1.4e-29 103.1 0.3 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 KDO16781.1 - 8.6e-07 28.6 0.2 1e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 Sugar transport protein EamA PF00892.20 KDO16781.1 - 0.009 16.2 1.1 0.009 16.2 1.1 1.8 1 1 1 2 2 2 1 EamA-like transporter family YhhN PF07947.14 KDO16781.1 - 0.011 15.4 2.3 0.014 15.0 2.3 1.2 1 0 0 1 1 1 0 YhhN family Peptidase_M14 PF00246.24 KDO16786.1 - 4.4e-06 26.7 0.1 5.6e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Semialdhyde_dh PF01118.24 KDO16787.1 - 2.6e-07 31.1 0.1 7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KDO16787.1 - 0.0084 15.7 0.1 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KDO16787.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Auto_anti-p27 PF06677.12 KDO16788.1 - 2.2e-30 104.5 15.2 4.9e-16 58.6 5.5 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRPl_C4 PF17026.5 KDO16788.1 - 0.0025 17.9 2.7 0.86 9.7 0.2 2.3 2 0 0 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type CxC6 PF18721.1 KDO16788.1 - 0.0061 16.8 0.7 2 8.8 0.1 2.3 2 0 0 2 2 2 2 CxC6 like cysteine cluster associated with KDZ transposases zf-C2H2_jaz PF12171.8 KDO16788.1 - 0.0071 16.6 2.6 0.41 11.0 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding IBR PF01485.21 KDO16788.1 - 0.14 12.4 5.8 1.3 9.3 0.2 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-LITAF-like PF10601.9 KDO16788.1 - 0.17 12.2 8.3 2.7 8.3 0.2 2.4 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain DUF5327 PF17261.2 KDO16788.1 - 8.3 7.2 9.6 9 7.1 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5327) CLIP1_ZNF PF16641.5 KDO16788.1 - 9.1 6.3 7.3 3.7 7.5 1.1 2.3 2 0 0 2 2 2 0 CLIP1 zinc knuckle ubiquitin PF00240.23 KDO16789.1 - 0.00027 20.6 0.1 0.047 13.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family PI-PLC-X PF00388.19 KDO16789.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF829 PF05705.14 KDO16790.1 - 2.1e-07 31.1 0.0 2.3e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF829 PF05705.14 KDO16791.1 - 2.6e-31 109.4 0.0 2.9e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF829 PF05705.14 KDO16792.1 - 1.5e-35 123.3 0.0 1.8e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Glycolytic PF00274.19 KDO16793.1 - 0.015 14.1 0.0 4.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-I Catalase_C PF18011.1 KDO16793.1 - 0.021 14.5 0.0 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 C-terminal domain found in long catalases FN3_7 PF18447.1 KDO16793.1 - 0.13 12.5 2.3 17 5.8 0.0 3.4 3 0 0 3 3 3 0 Fibronectin type III domain APG17 PF04108.12 KDO16793.1 - 0.18 10.9 0.8 16 4.5 0.0 2.7 3 0 0 3 3 3 0 Autophagy protein Apg17 IQ PF00612.27 KDO16795.1 - 0.00015 21.2 18.3 0.025 14.3 1.8 5.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif SpoIID PF08486.10 KDO16798.1 - 0.067 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Stage II sporulation protein FA_hydroxylase PF04116.13 KDO16799.1 - 5.4e-30 104.5 12.7 5.4e-30 104.5 12.7 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA_lid_4 PF17864.1 KDO16800.1 - 0.057 13.2 0.2 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 RuvB AAA lid domain SseC PF04888.12 KDO16800.1 - 0.11 12.1 8.7 0.14 11.7 8.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PRT_C PF08372.10 KDO16800.1 - 0.13 12.0 0.8 0.45 10.3 0.3 2.1 2 1 1 3 3 3 0 Plant phosphoribosyltransferase C-terminal DivIC PF04977.15 KDO16800.1 - 0.34 10.7 3.2 0.37 10.6 1.3 2.0 1 1 0 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.20 KDO16800.1 - 1.1 9.3 10.1 0.07 13.1 4.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF932 PF06067.11 KDO16800.1 - 1.3 8.7 6.7 0.92 9.2 2.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF932) SlyX PF04102.12 KDO16800.1 - 1.7 9.3 11.1 0.12 13.1 4.5 2.5 2 1 0 2 2 2 0 SlyX DUF16 PF01519.16 KDO16800.1 - 2.1 8.9 7.1 13 6.4 7.1 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 COG2 PF06148.11 KDO16800.1 - 2.2 8.3 6.5 1.1 9.4 3.1 2.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 THOC7 PF05615.13 KDO16800.1 - 2.4 8.5 9.5 3.4 7.9 5.9 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 APG6_N PF17675.1 KDO16800.1 - 3.5 8.2 11.9 19 5.8 11.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Ank_2 PF12796.7 KDO16801.1 - 1.3e-12 48.1 0.0 1.6e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO16801.1 - 3.9e-09 36.0 0.1 0.002 18.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO16801.1 - 8e-09 35.6 0.1 0.0039 17.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO16801.1 - 3.2e-08 33.6 0.4 0.0052 17.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KDO16801.1 - 1.6e-07 31.8 0.1 4.3e-07 30.3 0.1 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) IQ PF00612.27 KDO16802.1 - 1.5e-05 24.4 1.7 2.7e-05 23.5 0.0 2.3 3 0 0 3 3 3 1 IQ calmodulin-binding motif DUF3584 PF12128.8 KDO16802.1 - 0.06 10.9 23.8 0.077 10.5 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ApoO PF09769.9 KDO16802.1 - 0.2 11.6 2.8 0.48 10.4 0.5 2.2 2 0 0 2 2 2 0 Apolipoprotein O Cep57_MT_bd PF06657.13 KDO16802.1 - 0.32 11.5 20.2 0.22 12.0 5.7 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 KDO16802.1 - 0.35 11.2 28.3 1 9.7 10.0 2.4 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KDO16802.1 - 0.37 9.6 31.1 0.43 9.4 17.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KDO16802.1 - 0.4 11.1 11.4 2.2 8.8 0.2 3.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 KDO16802.1 - 0.55 11.0 16.5 5.5 7.8 7.2 3.0 2 1 0 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 KDO16802.1 - 0.73 9.9 11.4 2.1 8.4 4.4 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CEP63 PF17045.5 KDO16802.1 - 0.8 9.6 23.5 0.43 10.4 12.9 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa PI3K_P85_iSH2 PF16454.5 KDO16802.1 - 1 9.0 25.2 0.92 9.1 1.8 3.3 2 2 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain E2F_CC-MB PF16421.5 KDO16802.1 - 1.4 9.4 11.5 2 8.8 3.4 2.3 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF2408 PF10303.9 KDO16802.1 - 1.7 9.2 20.4 0.4 11.2 9.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) YabA PF06156.13 KDO16802.1 - 2.6 8.7 21.0 0.86 10.3 4.3 2.8 2 2 1 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KDO16802.1 - 2.9 8.1 25.7 1.8 8.8 6.9 3.1 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 KDO16802.1 - 3.8 6.9 28.2 2.1 7.8 11.8 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 GrpE PF01025.19 KDO16802.1 - 6.4 6.4 25.2 4.7 6.8 8.2 2.9 1 1 1 2 2 2 0 GrpE HAUS-augmin3 PF14932.6 KDO16802.1 - 6.9 6.2 22.8 3.9 7.0 8.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TPR_1 PF00515.28 KDO16803.1 - 2.1e-23 81.1 1.1 1.9e-06 27.4 0.0 3.5 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO16803.1 - 6.2e-20 69.6 2.1 3.8e-05 23.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO16803.1 - 4.9e-15 54.9 2.1 2.3e-05 24.0 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KDO16803.1 - 2.3e-12 46.1 0.4 0.0016 18.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO16803.1 - 1.8e-10 41.0 0.8 3.2e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO16803.1 - 6.3e-06 26.2 3.4 0.002 18.4 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO16803.1 - 1.5e-05 25.4 0.3 0.00053 20.4 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO16803.1 - 1.6e-05 24.9 0.5 0.00088 19.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO16803.1 - 1.7e-05 25.2 0.3 0.03 15.1 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO16803.1 - 2.9e-05 24.6 0.1 0.037 14.7 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO16803.1 - 0.00017 21.4 0.2 9.4 6.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO16803.1 - 0.00025 21.5 0.1 2.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 KDO16803.1 - 0.0068 16.5 0.1 6.4 6.8 0.0 3.2 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) eIF3_N PF09440.10 KDO16803.1 - 0.0094 16.4 0.3 0.019 15.4 0.3 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain DUF5588 PF17826.1 KDO16803.1 - 0.018 13.9 0.4 0.043 12.7 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5588) ANAPC3 PF12895.7 KDO16803.1 - 0.035 14.3 3.7 0.25 11.6 3.6 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KDO16803.1 - 0.33 11.1 2.5 0.65 10.1 0.0 2.8 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat UPRTase PF14681.6 KDO16805.1 - 4.5e-24 85.1 0.0 4.8e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PrgI PF12666.7 KDO16807.1 - 0.36 11.6 5.3 0.53 11.0 0.5 2.1 2 0 0 2 2 2 0 PrgI family protein Glyco_hydro_62 PF03664.13 KDO16812.1 - 1.4e-08 34.4 0.1 1.7e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_30 PF02055.16 KDO16813.1 - 1.1e-16 60.8 0.0 1.4e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 30 TIM-barrel domain CrgA PF06781.12 KDO16814.1 - 5.5 7.1 8.1 0.15 12.2 0.4 2.3 2 1 0 2 2 2 0 Cell division protein CrgA DUF5381 PF17353.2 KDO16814.1 - 5.6 6.7 7.5 1.5 8.5 4.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5381) ARS2 PF04959.13 KDO16816.1 - 0.00041 20.8 0.6 0.0008 19.8 0.6 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-BED PF02892.15 KDO16816.1 - 0.021 14.8 0.8 0.071 13.1 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KDO16816.1 - 0.037 14.4 0.5 0.037 14.4 0.5 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KDO16816.1 - 0.13 13.2 0.2 0.13 13.2 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KDO16816.1 - 3.9 7.8 9.3 0.11 12.8 2.3 2.2 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SNARE_assoc PF09335.11 KDO16817.1 - 3.3e-06 27.6 5.9 9.9e-05 22.8 5.9 2.3 1 1 0 1 1 1 1 SNARE associated Golgi protein ELO PF01151.18 KDO16818.1 - 8.8e-69 231.8 19.4 1e-68 231.6 19.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_2 PF12796.7 KDO16819.1 - 0.00027 21.5 0.3 0.098 13.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16819.1 - 0.0065 17.0 1.7 0.15 12.7 0.3 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF5338 PF17273.2 KDO16821.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Helo_like_N PF17111.5 KDO16822.1 - 0.041 13.2 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins zf-B_box PF00643.24 KDO16824.1 - 1.4e-09 37.9 17.8 4.2e-07 30.0 3.4 2.4 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 KDO16824.1 - 0.003 17.2 0.1 0.15 11.6 0.3 2.7 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF4531 PF15041.6 KDO16824.1 - 0.012 15.8 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) PUMA PF15826.5 KDO16824.1 - 0.055 13.6 0.5 0.055 13.6 0.5 1.8 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis zf-Mss51 PF13824.6 KDO16824.1 - 0.068 13.3 3.3 0.2 11.8 3.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 IBR PF01485.21 KDO16824.1 - 0.83 9.9 12.6 4 7.7 3.2 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Keratin_2_tail PF16210.5 KDO16825.1 - 8.8 6.6 31.1 11 6.3 31.1 1.1 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail zf-LSD1 PF06943.12 KDO16826.1 - 9.5e-05 22.2 14.4 0.00082 19.2 4.0 5.5 6 0 0 6 6 6 2 LSD1 zinc finger zinc-ribbons_6 PF07191.12 KDO16826.1 - 0.00029 20.8 13.9 0.25 11.4 0.3 3.6 3 1 0 3 3 3 3 zinc-ribbons TackOD1 PF18551.1 KDO16826.1 - 0.0014 18.3 8.2 0.0014 18.3 8.2 2.3 2 1 0 2 2 2 1 Thaumarchaeal output domain 1 zinc_ribbon_4 PF13717.6 KDO16826.1 - 0.0065 16.4 1.2 0.0065 16.4 1.2 6.3 5 1 2 7 7 7 2 zinc-ribbon domain Ribosomal_S27e PF01667.17 KDO16826.1 - 0.015 15.0 1.1 0.015 15.0 1.1 5.3 4 2 2 6 6 6 0 Ribosomal protein S27 Zn_Tnp_IS1595 PF12760.7 KDO16826.1 - 0.098 12.6 0.1 0.098 12.6 0.1 5.2 4 2 0 4 4 4 0 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.14 KDO16826.1 - 0.15 11.9 0.3 0.45 10.4 0.3 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zinc_ribbon_12 PF11331.8 KDO16826.1 - 0.71 9.7 31.1 0.62 9.9 1.9 5.4 3 1 2 5 5 5 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KDO16826.1 - 1.6 8.9 27.8 11 6.2 0.2 6.1 4 1 4 8 8 8 0 Zinc ribbon domain Mu-like_Com PF10122.9 KDO16826.1 - 1.7 8.1 27.4 0.73 9.3 1.0 4.8 5 1 1 6 6 6 0 Mu-like prophage protein Com IBR PF01485.21 KDO16826.1 - 1.8 8.9 22.0 9.9 6.5 0.9 4.6 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KDO16826.1 - 2.5 8.4 28.5 1.2 9.4 0.9 5.6 4 2 2 6 6 6 0 zinc-ribbon PHD PF00628.29 KDO16826.1 - 3.3 7.7 0.0 3.3 7.7 0.0 5.1 3 1 1 4 4 4 0 PHD-finger zf-4CXXC_R1 PF10497.9 KDO16826.1 - 7.4 6.9 11.9 4.3 7.6 0.3 2.9 1 1 2 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DNA_RNApol_7kD PF03604.13 KDO16826.1 - 9.4 6.0 21.3 1.7 8.4 0.6 4.7 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Oscp1 PF10188.9 KDO16827.1 - 3.1e-65 219.5 5.1 4e-65 219.2 5.1 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 FYDLN_acid PF09538.10 KDO16827.1 - 2.3 8.9 7.6 17 6.1 7.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Notch PF00066.17 KDO16828.1 - 5.4e-06 26.8 13.8 1.6e-05 25.2 14.0 1.7 1 1 1 2 2 2 1 LNR domain RepA1_leader PF08048.12 KDO16828.1 - 0.04 14.2 0.9 8.2 6.8 1.0 3.0 2 0 0 2 2 2 0 Tap RepA1 leader peptide DUF4787 PF16029.5 KDO16828.1 - 0.31 11.2 3.1 0.63 10.2 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) LRR_4 PF12799.7 KDO16828.1 - 1.2 9.6 5.1 26 5.4 0.0 3.3 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Tim44 PF04280.15 KDO16829.1 - 9.3e-14 51.8 0.1 1e-13 51.7 0.1 1.0 1 0 0 1 1 1 1 Tim44-like domain AAR2 PF05282.11 KDO16830.1 - 1.4e-50 172.7 8.4 5.7e-36 124.6 7.4 2.0 1 1 1 2 2 2 2 AAR2 protein DUF111 PF01969.17 KDO16831.1 - 2e-109 366.2 0.0 2.2e-109 366.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 TRAPP PF04051.16 KDO16832.1 - 1.9e-11 43.9 0.0 2.1e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HlyE PF06109.13 KDO16833.1 - 0.032 13.6 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Haemolysin E (HlyE) Taxilin PF09728.9 KDO16836.1 - 0.089 12.0 1.6 0.084 12.0 1.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Phycobilisome PF00502.19 KDO16837.1 - 0.025 14.5 0.3 0.029 14.3 0.3 1.0 1 0 0 1 1 1 0 Phycobilisome protein Hydantoinase_B PF02538.14 KDO16837.1 - 0.1 11.0 1.1 0.098 11.1 1.1 1.0 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Sugar_transport PF06800.12 KDO16839.1 - 0.021 14.2 0.0 0.024 14.0 0.0 1.0 1 0 0 1 1 1 0 Sugar transport protein FYVE PF01363.21 KDO16840.1 - 4.6e-11 42.7 10.2 4.6e-11 42.7 10.2 1.8 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO16840.1 - 0.0024 18.1 7.6 0.0024 18.1 7.6 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger VanY PF02557.17 KDO16841.1 - 0.12 12.2 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DnaJ_C PF01556.18 KDO16843.1 - 1.3e-39 135.6 0.0 1.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KDO16843.1 - 1e-12 48.2 13.5 2.5e-12 46.9 13.5 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KDO16843.1 - 0.0012 18.8 16.4 0.065 13.2 5.2 3.5 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KDO16843.1 - 0.76 9.8 8.3 0.36 10.9 0.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ABM PF03992.16 KDO16844.1 - 8.5e-13 48.2 0.1 1e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 KDO16844.1 - 0.00052 19.5 0.0 0.00061 19.3 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase DUF1330 PF07045.11 KDO16844.1 - 0.022 15.1 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Dabb PF07876.12 KDO16844.1 - 0.038 14.6 0.0 0.049 14.3 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain PH PF00169.29 KDO16845.1 - 0.15 12.6 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 PH domain Peptidase_M50B PF13398.6 KDO16846.1 - 2.1e-06 27.5 9.5 3.8e-06 26.7 9.4 1.5 1 1 0 1 1 1 1 Peptidase M50B-like TMEM220 PF15071.6 KDO16846.1 - 0.048 14.4 4.9 1.2 9.9 3.0 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix WD40 PF00400.32 KDO16849.1 - 2.1e-28 98.0 10.2 3e-08 34.2 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO16849.1 - 5.8e-13 48.9 1.1 0.0006 20.1 0.1 5.4 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO16849.1 - 1.1e-05 24.6 0.1 0.038 13.0 0.0 2.9 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KDO16849.1 - 0.0055 16.6 0.1 0.51 10.3 0.1 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 KDO16849.1 - 0.023 14.6 0.2 0.061 13.2 0.1 1.9 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Gmad1 PF10647.9 KDO16849.1 - 0.051 13.3 0.1 1.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Ndufs5 PF10200.9 KDO16850.1 - 6.6e-05 23.1 0.0 8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KDO16850.1 - 0.037 14.4 1.0 0.07 13.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Ribosomal_L12 PF00542.19 KDO16851.1 - 2.2e-23 82.4 9.1 2.2e-23 82.4 9.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ricin_B_lectin PF00652.22 KDO16852.1 - 0.0016 18.7 0.0 0.0025 18.1 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 KDO16852.1 - 0.0035 17.0 0.3 0.0055 16.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Sds3 PF08598.11 KDO16853.1 - 4e-06 27.0 3.0 4e-06 27.0 3.0 1.4 2 0 0 2 2 2 1 Sds3-like TRPM_tetra PF16519.5 KDO16853.1 - 0.043 13.9 0.8 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM MCD_N PF17408.2 KDO16853.1 - 0.16 12.2 3.9 0.28 11.3 2.2 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Jun PF03957.13 KDO16854.1 - 0.34 10.8 5.3 0.035 14.0 1.2 1.5 2 0 0 2 2 2 0 Jun-like transcription factor Syntaxin-6_N PF09177.11 KDO16855.1 - 0.063 13.8 0.0 0.12 12.9 0.0 1.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HEAT PF02985.22 KDO16856.1 - 0.0015 18.7 0.2 0.33 11.3 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KDO16856.1 - 0.0081 16.7 2.1 0.23 12.0 0.0 2.9 3 0 0 3 3 3 1 HEAT-like repeat CENP-B_dimeris PF09026.10 KDO16856.1 - 0.021 15.2 0.9 2 8.8 0.4 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Importin_rep_6 PF18829.1 KDO16856.1 - 0.052 13.7 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Importin repeat 6 Cyclase PF04199.13 KDO16857.1 - 2.1e-15 57.1 0.0 2.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Ank_2 PF12796.7 KDO16858.1 - 4.2e-15 56.1 1.5 4.4e-08 33.6 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO16858.1 - 3.7e-12 46.5 1.0 6.2e-08 33.0 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO16858.1 - 4.4e-10 39.6 0.9 0.00015 22.0 0.1 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO16858.1 - 1.7e-08 34.5 8.2 0.05 14.1 0.3 3.5 2 1 1 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KDO16858.1 - 2.2e-08 33.7 1.4 0.1 13.2 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeat Peptidase_M13 PF01431.21 KDO16859.1 - 2.3e-68 229.9 0.0 2.8e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KDO16859.1 - 0.016 15.0 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M13 Peptidase_M48 PF01435.18 KDO16859.1 - 0.032 14.0 0.0 0.066 13.0 0.0 1.4 2 0 0 2 2 2 0 Peptidase family M48 NDK PF00334.19 KDO16860.1 - 2.9e-30 105.0 0.0 2.1e-29 102.2 0.0 1.9 2 0 0 2 2 2 1 Nucleoside diphosphate kinase MORN PF02493.20 KDO16861.1 - 7.9e-38 126.1 43.7 3.2e-07 29.9 1.1 8.4 8 0 0 8 8 8 8 MORN repeat HECT PF00632.25 KDO16863.1 - 5.4e-42 144.3 0.1 3.3e-30 105.6 0.0 2.0 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) CLZ PF16526.5 KDO16868.1 - 0.034 14.5 0.2 0.042 14.2 0.2 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UN_NPL4 PF11543.8 KDO16869.1 - 0.15 12.6 0.0 0.21 12.1 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 MMR_HSR1_Xtn PF16897.5 KDO16873.1 - 1e-38 131.6 0.0 2.2e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KDO16873.1 - 8.2e-20 71.0 0.1 3e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KDO16873.1 - 1e-15 57.5 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KDO16873.1 - 8.3e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO16873.1 - 0.00063 19.8 0.7 0.21 11.7 0.0 2.8 2 1 1 3 3 3 2 Dynamin family AAA_28 PF13521.6 KDO16873.1 - 0.016 15.5 0.1 0.045 14.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KDO16873.1 - 0.033 14.4 0.7 0.24 11.6 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO16873.1 - 0.035 13.6 0.3 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 KDO16873.1 - 0.046 14.1 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PUB PF09409.10 KDO16874.1 - 1.6e-10 40.8 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 KDO16874.1 - 1.4e-08 34.8 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 KDO16876.1 - 4.6e-09 36.0 0.0 1.3e-08 34.5 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Yip1 PF04893.17 KDO16877.1 - 6.6e-16 58.5 17.2 8.6e-16 58.1 17.2 1.2 1 0 0 1 1 1 1 Yip1 domain Globin PF00042.22 KDO16878.1 - 0.00019 22.0 0.6 0.0012 19.4 0.5 2.3 2 1 0 2 2 2 1 Globin PX PF00787.24 KDO16880.1 - 7e-11 42.1 0.0 9.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 PX domain CotH PF08757.11 KDO16880.1 - 0.049 13.1 0.0 0.059 12.9 0.0 1.0 1 0 0 1 1 1 0 CotH kinase protein YrpD PF15493.6 KDO16880.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, YrpD Ion_trans PF00520.31 KDO16881.1 - 4.5e-86 288.1 33.2 5.8e-47 160.0 4.4 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KDO16881.1 - 1.3e-06 27.4 38.3 0.022 13.4 1.5 6.1 4 2 2 6 6 6 6 Polycystin cation channel cNMP_binding PF00027.29 KDO16882.1 - 2.8e-19 69.0 0.0 5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO16882.1 - 1.6e-14 53.7 7.3 2.4e-14 53.2 7.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO16882.1 - 0.34 10.9 6.5 0.037 14.0 1.7 2.0 2 0 0 2 2 2 0 Ion channel Titin_Ig-rpts PF06582.12 KDO16883.1 - 0.046 13.7 3.3 0.31 11.0 0.1 2.7 3 0 0 3 3 3 0 Titin repeat Frankia_peptide PF14407.6 KDO16883.1 - 0.081 12.9 1.0 0.36 10.9 0.1 2.4 1 1 1 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. THOC7 PF05615.13 KDO16883.1 - 0.18 12.1 6.3 0.64 10.3 5.2 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Phage_GP20 PF06810.11 KDO16885.1 - 0.016 15.0 5.2 0.02 14.7 5.2 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 ArAE_2_N PF10337.9 KDO16885.1 - 0.12 11.3 1.9 0.13 11.2 1.9 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF5320 PF17253.2 KDO16885.1 - 0.92 10.6 3.4 0.78 10.9 0.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Vps5 PF09325.10 KDO16886.1 - 0.00079 19.0 1.6 0.0012 18.4 1.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DASH_Dad2 PF08654.10 KDO16886.1 - 0.015 15.7 0.3 0.025 15.0 0.3 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF4609 PF15382.6 KDO16886.1 - 0.016 15.0 0.1 0.044 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) Phage_GP20 PF06810.11 KDO16886.1 - 0.021 14.6 1.0 0.035 13.9 1.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Phi_1 PF04674.12 KDO16886.1 - 0.026 13.8 0.3 0.036 13.4 0.3 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region bZIP_1 PF00170.21 KDO16886.1 - 0.049 13.7 1.8 0.049 13.7 1.8 1.7 2 0 0 2 2 2 0 bZIP transcription factor DDA1 PF10172.9 KDO16886.1 - 0.085 13.1 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase DUF5320 PF17253.2 KDO16886.1 - 0.11 13.6 1.1 0.16 13.1 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF5375 PF17345.2 KDO16886.1 - 0.14 12.1 1.7 0.25 11.3 0.8 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5375) DUF4140 PF13600.6 KDO16886.1 - 1.1 9.7 6.7 0.21 12.0 1.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 KDO16888.1 - 0.01 16.0 3.0 0.012 15.7 3.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KDO16888.1 - 0.039 14.3 4.9 2.4 8.5 0.2 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KDO16888.1 - 0.054 13.6 4.1 0.054 13.6 4.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Terminase_1 PF03354.15 KDO16888.1 - 0.1 11.2 1.4 1.1 7.8 0.0 1.9 1 1 1 2 2 2 0 Phage Terminase pXO2-34 PF17362.2 KDO16888.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function bZIP_1 PF00170.21 KDO16888.1 - 0.33 11.1 4.3 0.32 11.1 1.7 1.9 1 1 2 3 3 3 0 bZIP transcription factor YabA PF06156.13 KDO16888.1 - 0.79 10.4 4.9 3.2 8.4 4.9 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DnaJ PF00226.31 KDO16889.1 - 8.4e-22 77.1 0.1 2.3e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain COLFI PF01410.18 KDO16889.1 - 0.16 11.2 0.4 0.22 10.8 0.4 1.2 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain BaffR-Tall_bind PF09256.10 KDO16889.1 - 0.21 11.4 0.2 0.45 10.3 0.2 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding MAS20 PF02064.15 KDO16889.1 - 0.32 11.1 6.8 3.2 7.8 0.5 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor EF-hand_7 PF13499.6 KDO16891.1 - 0.00091 19.6 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair DUF5580 PF17743.1 KDO16891.1 - 0.04 12.5 0.0 0.043 12.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_6 PF13405.6 KDO16891.1 - 0.041 13.8 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Globin PF00042.22 KDO16893.1 - 0.043 14.4 5.4 0.056 14.0 2.8 2.3 2 1 0 2 2 2 0 Globin PNGaseA PF12222.8 KDO16893.1 - 0.14 11.0 0.1 0.18 10.7 0.1 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A CBM_1 PF00734.18 KDO16894.1 - 6.7e-12 45.1 7.4 6.7e-12 45.1 7.4 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain LPMO_10 PF03067.15 KDO16894.1 - 2.9e-06 28.1 0.9 2.9e-06 28.1 0.9 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PT PF04886.12 KDO16894.1 - 0.0028 17.2 32.9 0.024 14.2 5.9 3.7 1 1 1 2 2 2 1 PT repeat IBR PF01485.21 KDO16895.1 - 9.8e-14 51.3 34.1 3.1e-08 33.7 6.2 4.1 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KDO16895.1 - 5.7e-07 29.3 1.8 5.7e-07 29.3 1.8 4.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO16895.1 - 1.8e-06 28.2 2.0 1.8e-06 28.2 2.0 4.8 5 2 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KDO16895.1 - 1.1e-05 25.2 2.1 1.1e-05 25.2 2.1 4.8 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO16895.1 - 0.00035 20.7 3.0 0.00035 20.7 3.0 5.2 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO16895.1 - 0.0064 16.4 2.4 0.0064 16.4 2.4 5.0 3 1 2 5 5 5 1 zinc-RING finger domain MoaE PF02391.17 KDO16896.1 - 5e-23 81.5 0.0 5.5e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 MoaE protein FYVE PF01363.21 KDO16897.1 - 1.3e-12 47.7 14.2 2.1e-12 47.0 14.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO16897.1 - 0.84 9.9 13.8 1.9 8.7 13.8 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger zf-AD PF07776.15 KDO16897.1 - 3.7 7.8 12.6 1.3 9.3 1.3 2.7 1 1 2 3 3 3 0 Zinc-finger associated domain (zf-AD) ABC_tran PF00005.27 KDO16898.1 - 3.1e-26 92.5 0.1 1.2e-25 90.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KDO16898.1 - 2.7e-22 79.7 11.1 5.5e-22 78.7 11.1 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO16898.1 - 2.1e-06 27.3 0.3 0.0026 17.2 0.1 2.4 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO16898.1 - 4.3e-05 23.5 0.2 0.36 10.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO16898.1 - 0.00067 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO16898.1 - 0.0014 18.9 2.1 0.021 15.1 0.7 2.8 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 KDO16898.1 - 0.0038 17.1 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO16898.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO16898.1 - 0.018 14.6 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KDO16898.1 - 0.018 15.3 0.1 0.26 11.5 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_membrane_2 PF06472.15 KDO16898.1 - 0.022 14.2 1.9 0.046 13.1 1.9 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_23 PF13476.6 KDO16898.1 - 0.06 13.8 1.2 0.092 13.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KDO16898.1 - 0.084 12.6 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Septin PF00735.18 KDO16898.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_30 PF13604.6 KDO16898.1 - 0.089 12.5 0.0 0.25 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KDO16898.1 - 0.1 13.1 0.1 1.9 8.9 0.1 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KDO16898.1 - 0.15 12.0 0.2 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KDO16898.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Cation_efflux PF01545.21 KDO16899.1 - 2.8e-48 164.3 1.5 4.2e-48 163.7 1.5 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 KDO16899.1 - 0.00011 21.6 7.4 0.00024 20.5 7.4 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4766 PF15973.5 KDO16899.1 - 0.0022 18.5 13.9 0.0052 17.4 13.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4766) NESP55 PF06390.12 KDO16899.1 - 0.0031 17.1 0.2 0.0046 16.6 0.2 1.2 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) DctM PF06808.12 KDO16900.1 - 0.002 17.1 0.7 0.0023 16.8 0.7 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Gly-zipper_Omp PF13488.6 KDO16900.1 - 0.0065 16.4 2.8 0.011 15.7 2.8 1.3 1 1 0 1 1 1 1 Glycine zipper Sacchrp_dh_NADP PF03435.18 KDO16902.1 - 1.2e-12 48.2 0.5 1.3e-12 48.1 0.5 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KDO16902.1 - 0.097 12.9 0.2 0.2 11.9 0.2 1.6 1 1 0 1 1 1 0 TrkA-N domain NMT PF01233.19 KDO16903.1 - 8.6e-75 249.9 0.0 1.7e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 KDO16903.1 - 4.2e-73 245.3 0.0 7.2e-73 244.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 KDO16903.1 - 0.00095 19.2 0.3 0.0019 18.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO16903.1 - 0.036 14.3 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Cytadhesin_P30 PF07271.11 KDO16903.1 - 0.24 10.9 1.6 30 4.1 2.3 2.3 2 0 0 2 2 2 0 Cytadhesin P30/P32 TPR_2 PF07719.17 KDO16905.1 - 0.0018 18.3 0.1 0.0057 16.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO16905.1 - 0.017 15.3 0.6 0.067 13.4 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO16905.1 - 0.037 14.3 0.1 0.079 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO16905.1 - 0.068 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 KDO16906.1 - 2e-10 41.0 0.0 2 9.4 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO16906.1 - 0.00017 21.8 0.0 0.17 12.2 0.0 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Aa_trans PF01490.18 KDO16907.1 - 2.7e-09 36.2 3.2 3.4e-09 35.9 3.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2157 PF09925.9 KDO16907.1 - 0.029 14.2 3.4 0.087 12.6 0.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF3959 PF13105.6 KDO16907.1 - 0.031 13.8 2.3 0.058 12.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF3099 PF11298.8 KDO16907.1 - 9.3 6.5 8.7 0.95 9.6 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) Pyr_redox_dim PF02852.22 KDO16908.1 - 3.3e-38 130.3 0.1 4.2e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Epimerase PF01370.21 KDO16909.1 - 4.1e-11 42.8 0.0 8e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KDO16909.1 - 1.8e-09 37.1 0.0 7.4e-09 35.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KDO16909.1 - 0.0085 15.3 1.2 0.015 14.5 0.2 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KDO16909.1 - 0.12 11.7 0.1 1.4 8.2 0.0 2.3 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase CxC4 PF18717.1 KDO16909.1 - 0.15 11.9 0.4 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Ras PF00071.22 KDO16910.1 - 9.6e-45 152.1 0.0 1.1e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO16910.1 - 1.1e-11 44.9 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KDO16910.1 - 3.9e-06 26.9 0.0 0.055 13.4 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO16910.1 - 4.6e-05 23.5 0.0 6.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO16910.1 - 8.1e-05 22.2 0.0 0.0002 20.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KDO16910.1 - 0.0077 16.6 0.0 0.019 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KDO16910.1 - 0.012 15.2 0.7 0.45 10.0 0.7 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TMF_DNA_bd PF12329.8 KDO16911.1 - 0.29 11.2 4.5 15 5.6 0.6 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KDO16911.1 - 6.1 7.1 19.7 0.43 10.8 0.2 4.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding PI3K_P85_iSH2 PF16454.5 KDO16912.1 - 0.06 12.9 17.1 0.32 10.6 0.5 4.2 4 1 0 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cep57_CLD_2 PF14197.6 KDO16912.1 - 0.08 13.0 0.5 0.08 13.0 0.5 5.3 3 2 1 5 5 5 0 Centrosome localisation domain of PPC89 PKcGMP_CC PF16808.5 KDO16912.1 - 0.15 12.0 6.6 0.28 11.1 0.3 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DASH_Dam1 PF08653.10 KDO16912.1 - 0.16 11.8 4.9 17 5.3 0.2 4.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 zf-C4H2 PF10146.9 KDO16912.1 - 0.98 9.7 15.5 3.2 8.0 3.7 2.6 1 1 0 2 2 2 0 Zinc finger-containing protein Phage_lysozyme2 PF18013.1 KDO16912.1 - 0.99 9.4 3.4 1.2 9.2 1.1 2.2 2 0 0 2 2 2 0 Phage tail lysozyme DUF948 PF06103.11 KDO16912.1 - 1.1 9.5 12.1 35 4.7 1.0 4.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KDO16912.1 - 1.5 9.2 28.1 0.14 12.5 7.7 2.8 2 1 0 2 2 2 0 Fez1 FapA PF03961.13 KDO16912.1 - 1.7 7.2 5.2 3.3 6.2 0.5 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A SPATA24 PF15175.6 KDO16912.1 - 5.6 6.8 19.2 0.11 12.3 3.3 3.5 2 1 1 3 3 3 0 Spermatogenesis-associated protein 24 GAS PF13851.6 KDO16912.1 - 5.7 6.2 27.7 0.58 9.5 3.8 4.0 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding BST2 PF16716.5 KDO16912.1 - 8.3 7.1 37.2 3.1 8.4 0.1 5.5 3 2 2 5 5 5 0 Bone marrow stromal antigen 2 DUF3584 PF12128.8 KDO16912.1 - 8.3 3.8 40.1 0.89 7.0 18.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Disintegrin PF00200.23 KDO16914.1 - 6.4e-19 68.5 93.3 1.3e-05 25.9 9.5 7.2 4 3 1 5 5 5 5 Disintegrin SKN1 PF03935.15 KDO16915.1 - 2.5e-48 164.7 17.5 1.6e-26 92.8 0.6 5.1 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) PP28 PF10252.9 KDO16917.1 - 3.2 8.3 13.1 0.1 13.0 2.1 3.0 3 0 0 3 3 3 0 Casein kinase substrate phosphoprotein PP28 SfLAP PF11139.8 KDO16918.1 - 0.0054 16.2 6.1 0.0054 16.2 6.1 1.5 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein WES_acyltransf PF03007.16 KDO16919.1 - 0.022 14.5 0.1 0.038 13.8 0.1 1.4 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1295 PF06966.12 KDO16920.1 - 1.6e-60 204.6 1.0 2e-60 204.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KDO16920.1 - 4.5e-08 33.2 3.2 1.8e-07 31.2 0.6 2.7 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KDO16920.1 - 0.002 18.5 0.8 0.0052 17.2 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KDO16920.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase CPP1-like PF11833.8 KDO16920.1 - 8 6.1 8.9 0.23 11.1 2.2 1.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TPR_10 PF13374.6 KDO16921.1 - 0.00015 21.5 0.1 0.00035 20.3 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO16921.1 - 0.0013 19.0 0.5 0.0022 18.3 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Guanylate_cyc PF00211.20 KDO16922.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain zf-CW PF07496.15 KDO16924.1 - 0.00092 19.2 0.3 0.002 18.1 0.3 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger TPR_19 PF14559.6 KDO16925.1 - 0.068 13.7 0.8 0.18 12.3 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO16925.1 - 0.075 13.9 2.0 0.67 10.9 1.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_S21 PF01165.20 KDO16925.1 - 0.14 11.9 0.0 0.41 10.4 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein S21 TPR_11 PF13414.6 KDO16925.1 - 0.26 11.0 0.2 0.71 9.6 0.0 1.8 2 0 0 2 2 2 0 TPR repeat zf-RING_11 PF17123.5 KDO16926.1 - 2.5e-05 23.9 0.5 2.5e-05 23.9 0.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO16926.1 - 8.8e-05 22.7 7.7 0.00023 21.4 7.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO16926.1 - 0.00014 21.6 10.0 0.00065 19.5 10.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO16926.1 - 0.00023 21.4 10.6 0.0008 19.7 10.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO16926.1 - 0.0032 17.4 4.5 0.0074 16.3 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO16926.1 - 0.015 15.2 9.5 0.038 13.9 9.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO16926.1 - 0.019 14.9 9.2 0.045 13.7 9.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 KDO16926.1 - 0.49 10.3 4.7 7.6 6.4 3.2 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Aa_trans PF01490.18 KDO16927.1 - 1.4e-17 63.6 5.6 1.7e-17 63.3 5.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RCC1 PF00415.18 KDO16930.1 - 2.5e-37 127.3 14.1 8.7e-11 42.3 0.7 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO16930.1 - 2.2e-15 56.0 14.0 3.4e-08 33.1 3.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat FGE-sulfatase PF03781.16 KDO16931.1 - 4.7e-22 78.8 5.0 7.5e-22 78.1 2.3 2.6 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KDO16931.1 - 2.5e-07 31.3 1.9 1.5e-06 28.7 0.2 2.6 2 0 0 2 2 2 1 DinB superfamily Ank_2 PF12796.7 KDO16933.1 - 1.6e-22 79.9 6.6 4.9e-13 49.5 1.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO16933.1 - 1.7e-21 76.0 4.8 1.7e-10 41.0 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO16933.1 - 1.3e-14 52.9 1.9 1.1e-05 25.4 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO16933.1 - 3.6e-14 52.9 1.2 0.0015 19.1 0.1 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO16933.1 - 1.2e-13 50.9 6.2 0.0019 18.6 0.2 3.6 4 0 0 4 4 4 3 Ankyrin repeat DUF1949 PF09186.11 KDO16933.1 - 0.01 15.7 0.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DnaJ PF00226.31 KDO16934.1 - 4e-21 74.9 0.6 5.9e-21 74.4 0.6 1.2 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 KDO16934.1 - 1.2e-15 57.9 29.7 3e-14 53.3 13.3 2.4 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein TMEM52 PF14979.6 KDO16934.1 - 0.18 11.7 5.4 0.24 11.3 4.2 1.9 2 0 0 2 2 2 0 Transmembrane 52 Corona_S2 PF01601.16 KDO16934.1 - 9.2 4.6 5.8 15 4.0 5.8 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FAM176 PF14851.6 KDO16936.1 - 0.019 14.6 0.2 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 FAM176 family MPP6 PF10175.9 KDO16936.1 - 0.24 11.9 3.1 0.78 10.2 3.1 1.8 1 1 0 1 1 1 0 M-phase phosphoprotein 6 LIN37 PF15306.6 KDO16936.1 - 0.4 10.9 3.3 0.52 10.5 3.1 1.4 1 1 0 1 1 1 0 LIN37 PIP5K PF01504.18 KDO16937.1 - 4.3e-71 239.3 0.0 8.3e-71 238.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-BED PF02892.15 KDO16937.1 - 0.08 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger 7TM_GPCR_Srsx PF10320.9 KDO16937.1 - 0.14 11.5 9.4 0.075 12.4 6.5 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx EcoEI_R_C PF08463.10 KDO16937.1 - 0.16 12.1 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 EcoEI R protein C-terminal 7tm_1 PF00001.21 KDO16937.1 - 1.5 8.1 6.6 0.17 11.2 1.8 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Rhomboid PF01694.22 KDO16938.1 - 3.9e-39 134.1 18.3 7.5e-39 133.1 16.4 1.9 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 KDO16938.1 - 0.0011 19.0 0.2 0.0011 19.0 0.2 1.7 2 1 0 2 2 2 1 Der1-like family DUF1751 PF08551.10 KDO16938.1 - 0.075 13.6 0.1 0.075 13.6 0.1 2.3 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) MnhB PF04039.13 KDO16938.1 - 0.93 9.8 14.4 0.91 9.8 0.3 3.1 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Transp_Tc5_C PF04236.15 KDO16939.1 - 2.4 8.6 17.2 0.56 10.6 1.4 3.9 1 1 2 3 3 3 0 Tc5 transposase C-terminal domain Peptidase_C1 PF00112.23 KDO16940.1 - 5.6e-40 137.8 2.2 7.3e-40 137.4 2.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Ank_4 PF13637.6 KDO16942.1 - 0.082 13.5 0.1 59 4.4 0.0 3.7 3 1 0 3 3 3 0 Ankyrin repeats (many copies) adh_short PF00106.25 KDO16944.1 - 6.9e-08 32.2 0.2 8.2e-08 31.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO16944.1 - 1.7e-06 28.1 0.2 2.4e-06 27.6 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KDO16944.1 - 0.00021 21.0 0.8 0.0003 20.4 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 KDO16944.1 - 0.0006 19.5 0.2 0.00073 19.2 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KDO16944.1 - 0.0049 16.7 0.7 0.0061 16.4 0.7 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 KDO16944.1 - 0.017 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KDO16944.1 - 0.023 14.1 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KDO16944.1 - 0.078 12.9 0.1 0.09 12.6 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4HBT PF03061.22 KDO16945.1 - 0.049 14.0 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Thioesterase superfamily TYW3 PF02676.14 KDO16949.1 - 2.2e-58 197.2 0.0 3.6e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase TYW3 Kelch_4 PF13418.6 KDO16949.1 - 1.5e-16 60.1 0.6 1.5e-07 31.3 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO16949.1 - 2.3e-13 49.9 0.0 6.1e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KDO16949.1 - 5.4e-13 48.9 1.9 9e-05 22.7 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO16949.1 - 1.5e-10 40.9 0.5 0.0043 17.0 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 KDO16949.1 - 5.7e-10 38.6 0.0 0.0014 18.2 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KDO16949.1 - 5.5e-06 26.2 2.1 0.044 13.8 0.0 3.5 4 0 0 4 4 4 2 Kelch motif RAG2 PF03089.14 KDO16949.1 - 0.083 11.9 0.1 0.35 9.8 0.0 1.9 1 1 1 2 2 2 0 Recombination activating protein 2 Abhydrolase_1 PF00561.20 KDO16950.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO16950.1 - 2.7e-09 36.6 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO16950.1 - 6.4e-05 23.7 2.3 0.00024 21.8 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Histone PF00125.24 KDO16952.1 - 2e-53 180.2 0.9 2.3e-53 180.1 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KDO16952.1 - 0.00035 21.2 2.1 0.00044 20.8 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KDO16952.1 - 0.0011 19.3 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KDO16952.1 - 0.0016 18.5 0.3 0.0028 17.7 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KDO16952.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO16952.1 - 0.059 13.5 0.1 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CorA PF01544.18 KDO16953.1 - 1.5e-52 178.7 5.2 5.8e-45 153.8 2.4 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein ESR1_C PF12743.7 KDO16953.1 - 0.052 13.3 0.4 0.14 11.9 0.4 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal EF-hand_6 PF13405.6 KDO16953.1 - 0.09 12.8 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 KDO16954.1 - 2e-76 256.9 0.2 2.3e-76 256.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO16954.1 - 9.5e-40 136.5 0.1 1.2e-39 136.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO16954.1 - 2.8e-09 36.7 0.1 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KDO16954.1 - 4.1e-07 30.6 3.2 8.9e-07 29.5 3.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KDO16954.1 - 2.2e-06 26.8 0.0 3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO16954.1 - 4.1e-05 22.7 0.2 6.1e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KDO16954.1 - 0.00075 19.2 0.1 0.67 9.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KDO16954.1 - 0.0028 17.1 0.3 0.0057 16.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO16954.1 - 0.0035 17.3 0.0 0.013 15.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 KDO16955.1 - 9.8e-14 51.0 10.4 1.4e-13 50.4 10.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO16955.1 - 4.6e-05 23.7 10.9 7.7e-05 22.9 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO16955.1 - 0.00014 21.7 11.5 0.00022 21.0 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO16955.1 - 0.0024 17.8 10.0 0.0038 17.2 10.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO16955.1 - 0.0079 16.1 10.1 0.013 15.3 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO16955.1 - 0.015 15.1 11.9 0.029 14.2 11.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KDO16955.1 - 0.22 11.3 8.0 0.43 10.4 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KDO16955.1 - 2.6 8.3 11.5 4.9 7.4 11.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EF-hand_7 PF13499.6 KDO16956.1 - 1.3e-23 83.2 3.8 2.6e-08 34.2 0.6 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO16956.1 - 3.1e-20 70.1 4.3 0.00059 19.2 0.0 5.7 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KDO16956.1 - 1.1e-18 65.4 6.6 0.0014 18.4 0.0 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KDO16956.1 - 3.5e-14 52.4 6.1 0.00015 21.5 0.2 5.0 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO16956.1 - 7.6e-11 41.0 5.3 0.57 9.8 0.0 5.5 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.9 KDO16956.1 - 3e-09 37.2 0.0 0.15 12.4 0.0 3.3 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KDO16956.1 - 0.0043 17.0 0.3 1.5 8.7 0.0 3.6 4 0 0 4 4 4 1 Tellurite resistance protein TerB EF-hand_9 PF14658.6 KDO16956.1 - 0.0085 16.4 0.1 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KDO16956.1 - 0.063 13.2 3.3 0.4 10.6 0.3 3.1 3 2 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KDO16956.1 - 0.081 12.8 1.6 44 3.9 0.2 3.8 3 1 0 3 3 3 0 Caleosin related protein DNA_ligase_OB_2 PF14743.6 KDO16958.1 - 3.1e-26 91.2 0.2 6.1e-26 90.2 0.2 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain BRCT PF00533.26 KDO16958.1 - 3.1e-16 59.5 0.0 8.8e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KDO16958.1 - 9.2e-12 44.7 0.2 7.9e-10 38.6 0.1 2.7 2 0 0 2 2 2 1 twin BRCT domain DNA_ligase_A_M PF01068.21 KDO16958.1 - 1.7e-10 40.9 0.0 3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 KDO16958.1 - 7e-08 32.8 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Thioredoxin_8 PF13905.6 KDO16959.1 - 4.5e-16 59.0 0.0 5.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO16959.1 - 9e-07 28.8 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KDO16959.1 - 1.9e-05 24.5 0.0 2.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO16959.1 - 6.5e-05 22.7 0.0 7.5e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 KDO16959.1 - 0.049 14.1 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO16959.1 - 0.057 13.6 0.0 0.091 12.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 KDO16959.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_9 PF14595.6 KDO16959.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Myb_DNA-binding PF00249.31 KDO16962.1 - 5e-10 39.4 0.2 7.7e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO16962.1 - 0.00015 21.9 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3275 PF11679.8 KDO16962.1 - 0.14 12.1 7.9 0.18 11.8 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MFS_1 PF07690.16 KDO16963.1 - 1.2e-10 40.9 25.7 1.2e-10 40.9 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KDO16964.1 - 0.00074 18.5 5.3 0.00091 18.2 5.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ycf66_N PF07444.11 KDO16966.1 - 0.041 14.0 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 Ycf66 protein N-terminus Ricin_B_lectin PF00652.22 KDO16968.1 - 1.3e-16 61.0 0.9 1.9e-16 60.4 0.9 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO16968.1 - 1.2e-10 42.0 0.7 4.9e-06 27.2 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF1181 PF06680.11 KDO16969.1 - 0.041 13.7 0.2 0.05 13.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1181) Glyco_hydro_72 PF03198.14 KDO16971.1 - 1.8e-34 119.4 0.2 1.7e-24 86.7 0.1 2.7 1 1 1 2 2 2 2 Glucanosyltransferase DSBA PF01323.20 KDO16972.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF4200 PF13863.6 KDO16973.1 - 4.4e-35 120.7 22.5 4.4e-35 120.7 22.5 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) DUF948 PF06103.11 KDO16973.1 - 0.38 11.1 6.4 1.3 9.3 1.7 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YvrJ PF12841.7 KDO16973.1 - 0.39 10.3 1.1 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 YvrJ protein family NPV_P10 PF05531.12 KDO16973.1 - 6.9 7.2 11.3 0.91 10.0 0.3 3.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein p450 PF00067.22 KDO16975.1 - 4.5e-05 22.4 0.0 5.2e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3510 PF12022.8 KDO16977.1 - 4.2e-25 88.6 0.0 9.2e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) TALPID3 PF15324.6 KDO16979.1 - 0.0079 13.9 0.8 0.009 13.8 0.8 1.0 1 0 0 1 1 1 1 Hedgehog signalling target P33MONOX PF15302.6 KDO16979.1 - 0.092 12.4 0.8 0.11 12.2 0.8 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase zf-CCHC_2 PF13696.6 KDO16980.1 - 4.6e-06 26.3 6.1 7.6e-06 25.6 6.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KDO16980.1 - 5.8e-06 26.5 1.0 0.001 19.3 0.1 2.3 1 1 1 2 2 2 2 Retrotransposon gag protein zf-CCHC PF00098.23 KDO16980.1 - 0.00031 20.7 5.4 0.00031 20.7 5.4 2.2 2 0 0 2 2 2 1 Zinc knuckle Ribonuc_red_lgN PF00317.21 KDO16980.1 - 2.8 8.0 4.8 25 5.0 0.1 2.9 3 0 0 3 3 3 0 Ribonucleotide reductase, all-alpha domain Abhydrolase_3 PF07859.13 KDO16981.1 - 2.1e-28 99.6 0.1 2.8e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KDO16981.1 - 2e-15 56.6 0.0 2.3e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KDO16981.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KDO16981.1 - 0.025 14.1 0.0 0.11 12.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) COesterase PF00135.28 KDO16981.1 - 0.1 11.4 0.1 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Rotamase_3 PF13616.6 KDO16985.1 - 1.2e-17 64.5 0.0 1.8e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KDO16985.1 - 1.2e-13 51.8 0.0 1.7e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KDO16985.1 - 0.0023 18.7 0.0 0.003 18.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain RibD_C PF01872.17 KDO16987.1 - 0.013 15.4 0.1 0.014 15.2 0.1 1.0 1 0 0 1 1 1 0 RibD C-terminal domain Skp1_POZ PF03931.15 KDO16988.1 - 1.6e-21 76.2 0.1 2.7e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KDO16988.1 - 1.4e-12 47.5 0.1 3e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 KDO16988.1 - 7.1e-05 23.0 0.1 0.00071 19.8 0.1 2.0 1 1 0 1 1 1 1 BTB/POZ domain IFT46_B_C PF12317.8 KDO16988.1 - 0.028 14.1 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF3138 PF11336.8 KDO16989.1 - 2.2 6.8 3.5 2.6 6.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Metallophos PF00149.28 KDO16990.1 - 2.6e-06 28.1 1.9 1.5e-05 25.6 1.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP1 PF08601.10 KDO16990.1 - 0.043 13.6 0.8 0.067 12.9 0.8 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 FSA_C PF10479.9 KDO16990.1 - 1.9 6.6 5.3 2.5 6.1 5.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Disintegrin PF00200.23 KDO16991.1 - 3.7e-26 91.7 123.2 3.5e-05 24.5 12.7 9.6 7 4 0 7 7 7 7 Disintegrin Bromodomain PF00439.25 KDO16994.1 - 1.4e-31 108.4 0.0 1.2e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 Bromodomain PGA2 PF07543.12 KDO16994.1 - 0.79 9.7 9.3 1.3 9.0 9.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 KDO16994.1 - 4.5 5.2 15.2 6.9 4.6 15.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_17 PF00332.18 KDO16997.1 - 3.6e-05 23.5 0.1 0.0003 20.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF4232 PF14016.6 KDO17000.1 - 0.32 11.1 4.2 0.31 11.2 3.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) DAHP_synth_1 PF00793.20 KDO17001.1 - 1.4e-96 322.6 0.0 2.2e-96 322.0 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family DUF4442 PF14539.6 KDO17002.1 - 1.2e-31 109.5 0.2 1.4e-31 109.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) LRR_4 PF12799.7 KDO17003.1 - 0.00032 21.0 0.3 0.00094 19.5 0.1 2.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO17003.1 - 0.025 14.6 0.1 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KDO17003.1 - 0.03 14.8 0.3 1.5 9.6 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat NMO PF03060.15 KDO17004.1 - 4.6e-18 65.7 0.0 6.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KDO17004.1 - 0.15 11.0 0.0 0.32 9.9 0.0 1.5 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain KH_1 PF00013.29 KDO17005.1 - 2.1e-05 24.3 0.0 0.62 9.9 0.0 3.4 3 0 0 3 3 3 2 KH domain YuzL PF14115.6 KDO17006.1 - 0.0006 20.2 18.5 0.66 10.5 0.8 4.7 4 3 0 4 4 4 3 YuzL-like protein TMEM247 PF15444.6 KDO17006.1 - 0.034 14.2 6.5 0.062 13.3 1.6 2.1 1 1 1 2 2 2 0 Transmembrane protein 247 DUF908 PF06012.12 KDO17006.1 - 4.8 6.5 9.8 6.2 6.1 9.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SNAP PF14938.6 KDO17007.1 - 0.0097 15.4 1.1 0.0097 15.4 1.1 2.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP ABATE PF07336.11 KDO17008.1 - 0.072 13.8 3.5 3.6 8.3 1.2 3.0 2 1 0 2 2 2 0 Putative stress-induced transcription regulator Fungal_KA1 PF16797.5 KDO17008.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal kinase associated-1 domain AbiJ_NTD5 PF18865.1 KDO17008.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 HEAT_2 PF13646.6 KDO17008.1 - 0.13 12.6 6.0 1.7 9.1 0.2 4.2 4 2 1 5 5 5 0 HEAT repeats TAF4 PF05236.14 KDO17009.1 - 0.059 13.1 1.1 0.076 12.8 1.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GPI-anchored PF10342.9 KDO17010.1 - 0.0044 17.8 0.0 0.005 17.6 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 KDO17011.1 - 3.2e-48 164.4 0.0 3.7e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17011.1 - 2.4e-23 82.7 0.0 5e-23 81.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO17011.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO17011.1 - 0.12 12.3 2.0 0.14 12.1 0.3 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO17012.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain GTP_EFTU PF00009.27 KDO17013.1 - 4.4e-23 81.8 0.5 8.3e-23 80.9 0.5 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO17013.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KDO17013.1 - 0.0011 19.3 0.0 0.0037 17.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 KDO17013.1 - 0.0035 16.9 0.3 0.14 11.7 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KDO17013.1 - 0.008 15.2 0.5 0.32 9.9 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KDO17013.1 - 0.031 14.0 0.6 11 5.8 0.0 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PCI PF01399.27 KDO17015.1 - 1.3e-19 70.6 0.7 7.1e-18 65.1 0.2 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KDO17015.1 - 1.2e-09 37.7 0.1 4e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KDO17015.1 - 0.046 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain CHASE3 PF05227.13 KDO17016.1 - 0.017 15.0 0.8 0.017 15.0 0.8 4.6 2 2 0 3 3 3 0 CHASE3 domain T7SS_ESX_EspC PF10824.8 KDO17016.1 - 6.7 7.3 8.7 11 6.5 0.2 3.7 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF4419 PF14388.6 KDO17017.1 - 2e-90 303.3 0.0 2.3e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) UCH PF00443.29 KDO17018.1 - 4.5e-45 154.2 0.0 6.5e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO17018.1 - 1.2e-33 117.1 0.8 2.3e-33 116.2 0.1 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TUG-UBL1 PF11470.8 KDO17018.1 - 0.11 12.8 0.0 0.87 9.9 0.0 2.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain MRNIP PF15749.5 KDO17018.1 - 0.2 12.4 0.8 6.6 7.5 0.0 2.8 2 0 0 2 2 2 0 MRN-interacting protein Mpp10 PF04006.12 KDO17020.1 - 0.1 11.0 4.2 0.14 10.5 4.2 1.2 1 0 0 1 1 1 0 Mpp10 protein MTS PF05175.14 KDO17024.1 - 1.7e-10 40.7 0.0 1.3e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KDO17024.1 - 3.4e-05 23.4 0.0 0.00058 19.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO17024.1 - 0.00069 20.3 0.0 0.0013 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KDO17024.1 - 0.0042 16.8 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase UPF0020 PF01170.18 KDO17024.1 - 0.0051 16.5 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KDO17024.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Exo_endo_phos PF03372.23 KDO17025.1 - 1.3e-10 41.3 0.0 2.8e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aminotran_3 PF00202.21 KDO17026.1 - 0.0002 20.1 0.0 0.00021 20.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Thioredoxin PF00085.20 KDO17028.1 - 3.8e-24 84.6 0.1 4.4e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO17028.1 - 1.3e-05 25.6 0.2 0.00039 20.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO17028.1 - 2.1e-05 24.6 0.0 3.6e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KDO17028.1 - 4e-05 23.4 0.0 4.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KDO17028.1 - 0.0014 18.5 0.1 0.0026 17.7 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KDO17028.1 - 0.0016 18.7 0.0 0.05 13.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 KDO17028.1 - 0.003 17.3 0.1 0.034 13.9 0.0 2.0 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 KDO17028.1 - 0.0035 17.5 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 KDO17028.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KDO17029.1 - 1e-09 38.3 0.0 1.1e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Lactamase_B PF00753.27 KDO17030.1 - 1.4e-08 35.0 2.5 6.2e-08 32.9 2.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Sulfotransfer_3 PF13469.6 KDO17030.1 - 0.048 14.0 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family CxxCxxCC PF03692.15 KDO17031.1 - 1.5e-13 51.2 2.1 2.6e-13 50.4 2.1 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain MgtE_N PF03448.17 KDO17031.1 - 0.015 15.9 0.4 0.053 14.1 0.1 1.9 2 0 0 2 2 2 0 MgtE intracellular N domain Pox_Rif PF03340.13 KDO17031.1 - 0.088 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein EF-hand_1 PF00036.32 KDO17034.1 - 8.6e-07 28.1 0.7 0.015 14.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KDO17034.1 - 1.1e-06 28.1 3.9 0.057 13.4 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KDO17034.1 - 2.6e-06 27.8 2.2 0.0013 19.1 0.7 2.7 2 2 0 2 2 2 2 EF-hand domain pair MtN3_slv PF03083.16 KDO17035.1 - 8.4e-20 70.6 8.3 2e-09 37.4 0.0 2.9 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange Peptidase_C1_2 PF03051.15 KDO17036.1 - 2.8e-138 461.4 0.0 3.2e-138 461.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO17036.1 - 5.4e-06 26.6 0.6 0.00082 19.5 0.3 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Abhydrolase_1 PF00561.20 KDO17039.1 - 1.1e-16 61.3 0.0 1.7e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO17039.1 - 8.8e-11 41.5 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO17039.1 - 2.5e-09 38.1 1.0 4.4e-09 37.3 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KDO17039.1 - 0.044 13.6 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ank_2 PF12796.7 KDO17040.1 - 3.9e-06 27.4 2.4 8.3e-06 26.3 0.5 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17040.1 - 4.2e-06 27.2 3.3 0.0015 19.0 0.2 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17040.1 - 3.9e-05 23.7 2.3 5.1 8.0 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KDO17040.1 - 0.37 11.2 3.0 1 9.8 0.1 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LRAT PF04970.13 KDO17041.1 - 8.2e-07 29.4 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Cep57_MT_bd PF06657.13 KDO17041.1 - 0.075 13.5 0.7 0.15 12.5 0.7 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 NOA36 PF06524.12 KDO17041.1 - 3.7 6.8 13.2 5.9 6.1 13.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1664 PF07889.12 KDO17044.1 - 0.091 12.8 1.0 2.6 8.1 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3631 PF12307.8 KDO17044.1 - 0.16 12.2 3.0 0.8 9.9 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3631) Pkinase PF00069.25 KDO17045.1 - 4.2e-50 170.6 0.0 5.1e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17045.1 - 4.1e-29 101.7 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO17045.1 - 4.2e-05 23.0 0.2 7.5e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO17045.1 - 0.00012 21.6 0.1 0.00066 19.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KDO17045.1 - 0.00017 21.6 1.2 0.13 12.2 0.1 2.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO17045.1 - 0.074 12.0 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO17045.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MMR_HSR1 PF01926.23 KDO17048.1 - 3.2e-21 75.6 0.2 8e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO17048.1 - 3.4e-10 39.8 0.1 3.2e-07 30.1 0.1 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KDO17048.1 - 6.4e-10 39.3 2.1 8.2e-05 22.7 0.1 2.6 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 KDO17048.1 - 6.6e-09 35.5 0.3 1.2e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KDO17048.1 - 6.6e-09 35.4 0.2 1.3e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KDO17048.1 - 1.3e-05 25.1 0.6 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KDO17048.1 - 0.00056 20.2 0.1 0.0022 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain Arf PF00025.21 KDO17048.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO17048.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KDO17048.1 - 0.0018 18.1 0.1 0.022 14.6 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GBP PF02263.19 KDO17048.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Roc PF08477.13 KDO17048.1 - 0.022 15.0 0.0 0.061 13.5 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KDO17048.1 - 0.041 13.5 1.6 0.22 11.1 0.8 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KDO17048.1 - 0.084 12.1 0.3 0.28 10.4 0.1 1.9 2 1 0 2 2 2 0 Septin AAA_16 PF13191.6 KDO17048.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain HlyE PF06109.13 KDO17049.1 - 2e-15 56.9 0.1 2.6e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Haemolysin E (HlyE) DUF2732 PF10809.8 KDO17049.1 - 0.022 14.6 1.5 0.065 13.1 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) CTK3 PF12243.8 KDO17049.1 - 0.039 14.0 0.4 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Baculo_PEP_C PF04513.12 KDO17049.1 - 0.052 13.6 1.1 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1269 PF06897.12 KDO17049.1 - 0.12 12.7 0.3 0.25 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TALPID3 PF15324.6 KDO17051.1 - 0.43 8.2 4.4 0.42 8.2 4.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DEC-1_N PF04625.13 KDO17051.1 - 0.44 9.5 11.0 0.47 9.4 11.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region C2 PF00168.30 KDO17052.1 - 3.4e-22 78.7 0.0 2e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain Pex24p PF06398.11 KDO17052.1 - 0.011 14.7 4.4 0.012 14.6 4.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Sel1 PF08238.12 KDO17053.1 - 3.3e-12 46.6 27.7 2.8e-05 24.6 0.4 7.2 7 1 0 7 7 7 4 Sel1 repeat TPR_7 PF13176.6 KDO17053.1 - 0.011 15.7 6.9 5.2 7.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO17053.1 - 3.4 8.5 19.4 17 6.3 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat C12orf66_like PF09404.10 KDO17055.1 - 2.1e-25 89.5 3.2 5.5e-08 32.1 0.1 4.1 4 0 0 4 4 4 4 KICSTOR complex C12orf66 like FtsX_ECD PF18075.1 KDO17055.1 - 0.23 12.1 0.2 1.2 9.8 0.0 2.0 1 1 1 2 2 2 0 FtsX extracellular domain ThiF PF00899.21 KDO17056.1 - 3.1e-70 236.3 0.1 3.8e-70 236.0 0.1 1.0 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KDO17056.1 - 1.5e-10 41.5 0.3 8.5e-06 25.9 0.1 3.0 2 1 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KDO17056.1 - 4.2e-05 23.9 0.3 0.00011 22.6 0.1 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KDO17056.1 - 0.0011 19.1 0.2 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KDO17056.1 - 0.0011 19.3 0.9 0.0038 17.5 0.9 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KDO17056.1 - 0.08 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KDO17056.1 - 0.089 13.4 0.6 0.2 12.3 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KDO17056.1 - 0.091 13.0 0.1 0.28 11.4 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain HECT PF00632.25 KDO17058.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 KDO17059.1 - 2.9e-25 89.4 0.0 3e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KDO17060.1 - 5.5e-05 22.6 2.8 0.00018 21.0 2.8 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2890 PF11081.8 KDO17060.1 - 0.013 15.6 3.6 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Myb_DNA-binding PF00249.31 KDO17061.1 - 2.3e-11 43.7 0.0 3.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain MFS_2 PF13347.6 KDO17063.1 - 1.3e-05 24.0 31.9 0.0025 16.5 18.6 3.7 2 2 0 2 2 2 2 MFS/sugar transport protein LRR_4 PF12799.7 KDO17064.1 - 4.2e-07 30.2 5.2 0.00079 19.8 3.4 4.0 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO17064.1 - 5.7e-07 29.2 3.5 2.4e-06 27.2 0.9 2.9 2 1 0 2 2 2 1 Leucine rich repeat Notch PF00066.17 KDO17064.1 - 1e-05 25.9 6.1 2.2e-05 24.8 6.1 1.6 1 0 0 1 1 1 1 LNR domain LRR_9 PF14580.6 KDO17064.1 - 0.0071 15.9 2.1 0.0085 15.6 0.8 1.7 2 0 0 2 2 2 1 Leucine-rich repeat GMC_oxred_N PF00732.19 KDO17065.1 - 5.9e-39 134.2 0.1 6.4e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KDO17065.1 - 1.8e-05 24.8 0.3 6.3e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KDO17065.1 - 0.002 17.3 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KDO17065.1 - 0.0047 16.6 0.2 0.0049 16.5 0.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO17065.1 - 0.021 14.1 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KDO17065.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KDO17065.1 - 0.078 11.7 0.1 0.099 11.3 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KDO17065.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Peptidase_S8 PF00082.22 KDO17066.1 - 3.8e-40 138.0 0.3 7.3e-40 137.1 0.3 1.5 1 0 0 1 1 1 1 Subtilase family HTH_25 PF13413.6 KDO17066.1 - 0.048 13.5 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF493 PF04359.14 KDO17066.1 - 0.066 13.8 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF493) Cohesin_HEAT PF12765.7 KDO17066.1 - 0.098 13.0 0.6 0.22 11.9 0.6 1.6 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion MJ1316 PF04457.12 KDO17067.1 - 3.5e-24 85.3 2.2 5.7e-24 84.6 2.2 1.3 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain RWD PF05773.22 KDO17067.1 - 0.025 14.8 0.0 0.93 9.8 0.0 2.3 1 1 0 1 1 1 0 RWD domain CCDC53 PF10152.9 KDO17067.1 - 0.12 12.8 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TPR_2 PF07719.17 KDO17068.1 - 1.8e-05 24.5 12.2 2.1 8.7 0.1 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO17068.1 - 5.8e-05 22.7 3.3 0.12 12.1 0.1 4.0 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 KDO17068.1 - 0.0018 18.0 0.0 18 5.3 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO17068.1 - 0.012 15.7 1.2 0.012 15.7 1.2 4.8 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO17068.1 - 0.066 13.9 0.4 0.066 13.9 0.4 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO17068.1 - 0.21 12.0 10.8 0.75 10.3 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17068.1 - 2.5 9.1 31.3 21 6.3 0.4 9.3 6 1 5 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO17068.1 - 6 7.4 12.1 1.1e+02 3.4 0.1 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat ParcG PF10274.9 KDO17069.1 - 4.1e-22 79.2 0.0 5.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Sensor PF13796.6 KDO17070.1 - 0.088 12.9 10.6 0.14 12.2 8.0 2.0 1 1 1 2 2 2 0 Putative sensor ODV-E18 PF10717.9 KDO17070.1 - 2.8 7.9 6.9 3 7.8 2.3 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pkinase PF00069.25 KDO17071.1 - 6.2e-61 206.1 0.0 7.7e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17071.1 - 2.9e-47 161.1 0.1 3.8e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO17071.1 - 1.3e-05 24.2 0.0 4.8e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO17071.1 - 0.0028 16.6 1.3 0.0062 15.5 1.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO17071.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO17071.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO17071.1 - 0.042 13.2 0.1 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO17071.1 - 0.066 12.8 0.4 0.15 11.6 0.4 1.6 1 1 0 1 1 1 0 RIO1 family Epimerase PF01370.21 KDO17072.1 - 0.085 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KDO17073.1 - 1.3e-07 30.9 31.7 1.1e-05 24.5 10.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5337 PF17272.2 KDO17073.1 - 1.1 9.1 6.8 8.3 6.3 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Endonuc-HincII PF09226.11 KDO17074.1 - 0.22 10.8 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease HincII MRP-S35 PF10246.9 KDO17076.1 - 0.087 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Thiolase_N PF00108.23 KDO17077.1 - 5.9e-13 48.8 0.1 6.4e-13 48.7 0.1 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Calcyon PF06387.11 KDO17077.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.0 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Ank_4 PF13637.6 KDO17080.1 - 8.7e-15 54.9 0.9 3e-09 37.2 0.2 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17080.1 - 2.8e-13 49.8 0.2 8.8e-07 29.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17080.1 - 5.1e-13 49.4 0.0 8.2e-06 26.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO17080.1 - 1.2e-12 47.6 0.9 0.00066 20.0 0.3 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KDO17080.1 - 2.5e-12 45.8 0.4 3.9e-05 23.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DMP1 PF07263.11 KDO17080.1 - 0.013 14.5 8.9 0.021 13.7 8.9 1.3 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) NOA36 PF06524.12 KDO17080.1 - 5.4 6.3 10.7 8.4 5.6 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein MAPEG PF01124.18 KDO17081.1 - 2.1e-16 60.0 1.9 2.8e-16 59.6 1.9 1.2 1 0 0 1 1 1 1 MAPEG family DUF1322 PF07032.11 KDO17083.1 - 0.11 13.0 0.4 24 5.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) DHC_N2 PF08393.13 KDO17084.1 - 9.1e-54 183.1 0.4 9.1e-54 183.1 0.4 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Vps5 PF09325.10 KDO17085.1 - 0.015 14.8 0.5 0.061 12.9 0.1 2.1 1 1 2 3 3 3 0 Vps5 C terminal like WXG100 PF06013.12 KDO17085.1 - 0.026 14.8 2.8 0.046 14.0 2.8 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Hemerythrin PF01814.23 KDO17085.1 - 2.8 8.6 10.4 1.6 9.4 2.0 2.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Peptidase_C48 PF02902.19 KDO17086.1 - 8.9e-08 32.2 0.0 2.7e-07 30.7 0.0 1.6 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Striatin PF08232.12 KDO17086.1 - 0.066 13.8 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 Striatin family Filo_VP35 PF02097.15 KDO17086.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Peptidase_C48 PF02902.19 KDO17087.1 - 8.6e-05 22.5 0.1 0.00014 21.7 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ank_2 PF12796.7 KDO17088.1 - 2e-63 211.0 23.2 3.3e-13 50.0 1.2 6.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17088.1 - 6.9e-57 189.1 20.8 4.8e-10 39.8 0.1 8.6 2 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17088.1 - 2.1e-47 153.6 24.6 9.7e-05 22.5 0.1 13.1 13 0 0 13 13 13 12 Ankyrin repeat Ank PF00023.30 KDO17088.1 - 7.7e-40 133.6 47.5 0.00011 22.5 0.4 12.9 12 1 1 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KDO17088.1 - 1.5e-38 130.3 34.6 1.2e-07 31.8 0.7 10.2 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 KDO17088.1 - 0.24 11.3 3.5 1.1e+02 2.8 0.0 4.9 4 0 0 4 4 4 0 Superinfection immunity protein Ank_2 PF12796.7 KDO17089.1 - 0.0032 18.0 0.3 0.0036 17.9 0.3 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17089.1 - 0.04 14.5 0.1 0.05 14.2 0.1 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ABC2_membrane PF01061.24 KDO17090.1 - 3.9e-71 238.8 71.1 4.3e-39 134.1 33.3 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KDO17090.1 - 4e-18 66.3 0.0 3.2e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter PDR_CDR PF06422.12 KDO17090.1 - 3e-07 30.2 9.9 0.00013 21.8 0.1 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KDO17090.1 - 5.2e-06 25.8 66.0 0.0018 17.4 30.7 3.5 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO17090.1 - 4.8e-05 23.3 0.5 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO17090.1 - 0.00016 21.7 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KDO17090.1 - 0.0029 17.3 1.1 0.021 14.5 0.5 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KDO17090.1 - 0.014 14.8 0.1 0.041 13.3 0.1 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO17090.1 - 0.02 15.1 0.1 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO17090.1 - 0.1 12.1 0.2 0.34 10.5 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO17090.1 - 0.15 12.4 0.1 0.53 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KDO17090.1 - 0.36 11.3 0.7 0.55 10.7 0.1 1.5 2 0 0 2 2 1 0 AAA domain Spore_YhaL PF14147.6 KDO17090.1 - 0.56 9.9 2.0 35 4.2 0.1 2.8 2 0 0 2 2 2 0 Sporulation protein YhaL PLAC8 PF04749.17 KDO17091.1 - 1.6e-09 38.7 2.6 2e-09 38.4 2.6 1.1 1 0 0 1 1 1 1 PLAC8 family fn3 PF00041.21 KDO17092.1 - 9.4e-47 157.3 0.0 1.7e-13 50.7 0.0 6.4 6 0 0 6 6 6 6 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO17092.1 - 5.3e-11 42.9 0.0 0.63 10.7 0.2 6.0 6 0 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain WD40 PF00400.32 KDO17092.1 - 1.4e-08 35.2 3.7 0.038 14.9 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat SusE PF14292.6 KDO17092.1 - 0.0047 17.1 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 SusE outer membrane protein Malate_DH PF12434.8 KDO17093.1 - 0.15 12.1 0.6 0.15 12.1 0.6 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Ank_2 PF12796.7 KDO17094.1 - 2.5e-34 117.7 10.8 3.8e-14 53.0 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO17094.1 - 8.3e-24 83.4 3.9 8.6e-08 32.3 0.8 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17094.1 - 7e-23 80.7 11.8 1.8e-06 28.4 0.4 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO17094.1 - 1.1e-20 73.0 9.9 1.2e-05 25.5 0.4 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KDO17094.1 - 5.2e-19 66.3 4.4 0.00081 19.7 0.0 6.3 5 0 0 5 5 5 4 Ankyrin repeat Ion_trans PF00520.31 KDO17094.1 - 4.1e-06 26.2 17.5 4.1e-06 26.2 17.5 2.1 1 1 1 2 2 2 1 Ion transport protein PhoLip_ATPase_C PF16212.5 KDO17095.1 - 2.8e-40 138.6 6.6 2.8e-40 138.6 6.6 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO17095.1 - 2.6e-18 65.5 0.2 7e-18 64.1 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO17095.1 - 6.9e-13 49.4 0.2 1.2e-06 29.0 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO17095.1 - 2.3e-11 43.6 0.0 9e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO17095.1 - 2.5e-09 36.9 0.1 2.5e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO17095.1 - 0.0058 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2781 PF10914.8 KDO17095.1 - 0.023 15.1 0.9 0.074 13.5 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) MpPF26 PF07666.11 KDO17095.1 - 0.2 11.7 2.8 0.45 10.6 2.8 1.6 1 0 0 1 1 1 0 M penetrans paralogue family 26 EF-hand_5 PF13202.6 KDO17096.1 - 9e-12 43.9 0.1 1.5e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 KDO17096.1 - 1.1e-11 43.4 0.2 9.3e-05 21.7 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO17096.1 - 4e-10 40.0 0.2 7.1e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO17096.1 - 5.1e-09 35.3 0.1 0.0012 18.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KDO17096.1 - 2.7e-06 27.1 0.0 1.4e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO17096.1 - 0.015 15.6 0.1 0.035 14.4 0.1 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.10 KDO17096.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Pseudomurein-binding repeat Ank_4 PF13637.6 KDO17097.1 - 2.7e-27 94.8 16.6 6.5e-06 26.6 0.8 8.8 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17097.1 - 6.5e-24 83.7 20.7 0.076 13.4 0.0 10.3 4 2 7 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17097.1 - 9.6e-23 80.6 9.5 6.5e-08 33.1 0.1 4.9 2 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17097.1 - 8.5e-13 47.3 8.8 1.4 9.7 0.0 10.8 12 0 0 12 12 12 2 Ankyrin repeat SAM_2 PF07647.17 KDO17097.1 - 0.041 14.0 0.6 24 5.1 0.0 3.9 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Ank PF00023.30 KDO17097.1 - 0.045 14.2 8.2 67 4.2 0.0 6.7 2 2 3 5 5 5 0 Ankyrin repeat DUF4880 PF16220.5 KDO17097.1 - 0.045 13.6 2.2 1.9 8.5 0.1 3.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) DUF249 PF03158.13 KDO17097.1 - 0.11 12.2 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Multigene family 530 protein HTH_23 PF13384.6 KDO17098.1 - 5.7e-08 32.3 0.2 8e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KDO17098.1 - 4.5e-05 23.6 0.2 0.00012 22.3 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KDO17098.1 - 5.4e-05 23.2 0.2 0.0001 22.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KDO17098.1 - 0.00032 20.3 0.4 0.0017 18.0 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 KDO17098.1 - 0.0011 18.9 0.2 0.0038 17.2 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KDO17098.1 - 0.0014 19.2 4.8 0.0014 19.2 2.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KDO17098.1 - 0.0037 17.1 0.2 0.27 11.2 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_Tnp_ISL3 PF13542.6 KDO17098.1 - 0.012 15.0 0.0 0.073 12.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.19 KDO17098.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_33 PF13592.6 KDO17098.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix COX15-CtaA PF02628.15 KDO17099.1 - 7.2e-43 146.9 0.2 9.9e-43 146.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PNGaseA PF12222.8 KDO17101.1 - 1e-88 298.1 3.3 1.3e-88 297.8 3.3 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A CBM_1 PF00734.18 KDO17103.1 - 2.3e-12 46.6 8.6 5.7e-12 45.4 8.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO17103.1 - 7.9e-07 28.5 31.3 0.00016 21.2 3.1 3.6 2 2 1 3 3 3 2 PT repeat DUF4106 PF13388.6 KDO17103.1 - 0.24 10.6 10.8 0.28 10.4 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Stk19 PF10494.9 KDO17105.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 Fer4_2 PF12797.7 KDO17107.1 - 0.064 13.4 3.4 0.064 13.4 3.4 1.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KDO17108.1 - 5.1 7.4 18.6 11 6.4 3.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Pyr_redox_2 PF07992.14 KDO17109.1 - 7.2e-31 107.5 0.1 9.4e-31 107.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO17109.1 - 1.6e-10 41.4 0.4 1.6e-07 31.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SH2 PF00017.24 KDO17109.1 - 2.8e-07 30.6 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Pyr_redox_3 PF13738.6 KDO17109.1 - 0.0002 20.8 0.0 0.00064 19.1 0.0 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KDO17109.1 - 0.00036 19.8 0.3 0.0024 17.1 0.2 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KDO17109.1 - 0.00041 20.0 6.9 1.6 8.2 3.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO17109.1 - 0.00073 19.7 1.2 0.098 12.9 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KDO17109.1 - 0.0012 18.8 4.1 0.084 12.9 0.0 4.0 2 2 2 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KDO17109.1 - 0.0052 15.9 0.3 0.023 13.8 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KDO17109.1 - 0.0059 15.9 0.6 0.62 9.3 0.4 2.3 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.21 KDO17109.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 KDO17109.1 - 0.16 10.8 1.0 8.2 5.1 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Abhydrolase_4 PF08386.10 KDO17110.1 - 2.4e-12 46.9 0.0 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KDO17111.1 - 0.0088 15.7 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1336 PF07059.12 KDO17112.1 - 1.6e-54 185.4 0.0 2.1e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) FAD-oxidase_C PF02913.19 KDO17113.1 - 1.5e-51 175.4 0.0 1.7e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Cyclin_N PF00134.23 KDO17114.1 - 0.0017 18.1 0.1 0.0031 17.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO17114.1 - 0.043 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain WW PF00397.26 KDO17115.1 - 0.12 12.4 5.1 0.46 10.6 5.1 1.8 1 1 0 1 1 1 0 WW domain RAB3GAP2_C PF14656.6 KDO17117.1 - 9.4e-15 53.9 0.0 1.2e-08 33.7 0.0 3.0 2 1 1 3 3 3 3 Rab3 GTPase-activating protein regulatory subunit C-terminus MRP_L53 PF10780.9 KDO17119.1 - 0.00077 19.6 0.2 0.0015 18.6 0.2 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF3455 PF11937.8 KDO17120.1 - 0.034 14.5 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Autoind_synth PF00765.17 KDO17121.1 - 0.043 13.4 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Autoinducer synthase GAS PF13851.6 KDO17122.1 - 0.0038 16.6 15.9 0.0038 16.6 15.9 4.5 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding Vip3A_N PF12495.8 KDO17122.1 - 0.086 12.7 0.5 1.6 8.6 0.2 2.8 2 1 1 3 3 3 0 Vegetative insecticide protein 3A N terminal Spc7 PF08317.11 KDO17122.1 - 0.4 9.5 55.4 1.7 7.4 19.9 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein Flagellin_N PF00669.20 KDO17122.1 - 3.3 7.8 12.2 0.23 11.6 5.1 2.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region APG17 PF04108.12 KDO17122.1 - 8.4 5.4 43.1 0.035 13.2 10.5 4.2 2 1 2 4 4 4 0 Autophagy protein Apg17 ATG16 PF08614.11 KDO17122.1 - 8.6 6.5 65.4 0.031 14.5 9.4 4.1 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KDO17122.1 - 9.7 6.7 68.2 0.033 14.7 15.7 4.8 2 1 1 4 4 4 0 Apg6 coiled-coil region Phage_integrase PF00589.22 KDO17123.1 - 4.2e-05 23.4 0.0 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family Ank_2 PF12796.7 KDO17124.1 - 1.3e-22 80.1 10.9 1.6e-07 31.8 0.6 6.4 5 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO17124.1 - 1.5e-14 53.9 18.7 0.0049 17.1 0.1 10.2 6 3 5 11 11 11 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17124.1 - 1.8e-13 50.7 19.0 1.6e-05 25.3 0.5 9.2 5 3 7 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17124.1 - 6.4e-09 35.3 13.3 12 6.8 0.0 11.2 12 1 1 13 13 13 2 Ankyrin repeat RicinB_lectin_2 PF14200.6 KDO17125.1 - 0.0055 17.4 3.2 0.037 14.7 0.5 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ank_2 PF12796.7 KDO17126.1 - 2.4e-11 44.1 0.4 1.3e-05 25.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO17126.1 - 7.1e-08 32.6 1.5 0.28 11.6 0.1 4.2 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17126.1 - 1.5e-07 31.8 0.3 0.00015 22.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17126.1 - 9.1e-06 25.7 0.2 2.6 8.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO17126.1 - 0.022 15.2 3.6 11 6.6 0.1 4.1 1 1 1 2 2 2 0 Ankyrin repeat DNA_pol_phi PF04931.13 KDO17127.1 - 0.052 11.7 14.0 0.078 11.1 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KDO17127.1 - 0.13 10.7 6.5 0.15 10.6 5.1 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KDO17127.1 - 0.15 10.3 4.1 0.22 9.8 4.1 1.3 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 KDO17127.1 - 0.25 11.8 0.7 2.9 8.4 0.4 3.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Sporozoite_P67 PF05642.11 KDO17127.1 - 0.45 8.5 6.0 0.64 8.0 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KDO17127.1 - 0.69 8.1 10.3 1 7.5 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KDO17127.1 - 1.1 8.5 8.0 1.9 7.8 8.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 KDO17127.1 - 1.9 7.8 10.6 2.7 7.3 10.6 1.1 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.6 KDO17127.1 - 3.1 7.5 8.8 5.5 6.7 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.14 KDO17127.1 - 4.7 6.9 10.8 13 5.5 10.8 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SpoIIE PF07228.12 KDO17128.1 - 0.0019 18.2 0.2 0.003 17.5 0.2 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) MU2_FHA PF18221.1 KDO17128.1 - 0.02 15.0 0.0 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Mutator 2 Fork head associated domain Pex16 PF08610.10 KDO17129.1 - 6.7e-59 199.7 0.0 8.4e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PDZ_2 PF13180.6 KDO17130.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Inv-AAD PF18785.1 KDO17131.1 - 1.7e-27 95.8 0.4 1e-25 90.1 0.4 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KDO17131.1 - 1.7e-21 76.0 1.3 2e-21 75.7 1.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KDO17131.1 - 7.3e-08 32.3 0.1 1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KDO17131.1 - 0.12 12.2 0.6 0.67 9.8 0.6 2.0 1 1 0 1 1 1 0 APOBEC-like N-terminal domain EF-hand_1 PF00036.32 KDO17133.1 - 7e-06 25.2 0.9 1.8e-05 23.9 0.9 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO17133.1 - 0.00043 20.0 1.0 0.0013 18.5 1.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KDO17133.1 - 0.0021 18.5 0.1 0.0061 17.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO17133.1 - 0.0042 16.5 1.0 0.01 15.3 1.0 1.6 1 0 0 1 1 1 1 EF hand RRN3 PF05327.11 KDO17133.1 - 0.042 12.4 0.7 0.064 11.8 0.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NHL PF01436.21 KDO17135.1 - 5.4e-22 76.7 5.5 8.3e-08 31.9 0.0 4.3 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 KDO17135.1 - 6.8e-07 29.1 0.1 0.0017 18.0 0.0 2.4 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 KDO17135.1 - 6.5e-05 22.8 0.0 0.073 13.1 0.0 2.9 2 0 0 2 2 2 2 Beta-propeller repeat OLF PF02191.16 KDO17135.1 - 0.049 13.1 0.1 2.2 7.7 0.0 2.7 1 1 2 3 3 3 0 Olfactomedin-like domain SdiA-regulated PF06977.11 KDO17135.1 - 0.056 12.7 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 SdiA-regulated US22 PF02393.16 KDO17135.1 - 0.059 13.6 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 US22 like E3_UbLigase_RBR PF18091.1 KDO17138.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain Tup_N PF08581.10 KDO17138.1 - 0.024 14.9 1.3 0.2 12.0 0.5 2.2 2 0 0 2 2 2 0 Tup N-terminal Fez1 PF06818.15 KDO17138.1 - 0.036 14.5 9.6 0.066 13.7 9.6 1.4 1 1 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 KDO17138.1 - 0.13 12.4 0.5 5.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 KDO17138.1 - 0.22 11.5 2.4 9.4 6.2 0.0 2.8 2 2 0 2 2 2 0 Prefoldin subunit Bap31_Bap29_C PF18035.1 KDO17138.1 - 0.26 11.3 2.8 0.79 9.8 0.8 2.6 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain TolA_bind_tri PF16331.5 KDO17138.1 - 0.86 9.7 5.6 4.3 7.5 2.9 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 KDO17138.1 - 0.94 10.0 7.2 1 9.9 3.7 2.3 2 1 0 2 2 2 0 Cell division protein ZapB GrpE PF01025.19 KDO17138.1 - 1.1 8.9 7.1 9 5.9 3.8 2.3 1 1 0 2 2 2 0 GrpE Jnk-SapK_ap_N PF09744.9 KDO17138.1 - 2.6 8.2 14.3 1.3 9.2 0.8 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KDO17138.1 - 7.6 6.8 8.0 12 6.2 2.6 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II ADIP PF11559.8 KDO17138.1 - 9.5 6.3 10.0 15 5.6 5.9 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding NUDIX PF00293.28 KDO17139.1 - 0.078 13.0 0.1 0.2 11.7 0.1 1.8 1 1 0 1 1 1 0 NUDIX domain PAP2 PF01569.21 KDO17141.1 - 2.4e-19 69.4 7.3 2.4e-19 69.4 7.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KDO17141.1 - 2.2e-05 24.2 10.4 0.0013 18.5 10.3 2.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KDO17141.1 - 0.0066 17.0 2.2 0.0066 17.0 2.2 2.5 2 1 0 2 2 2 1 PAP2 superfamily C-terminal AMP-binding PF00501.28 KDO17142.1 - 2.1e-42 145.2 0.5 3.5e-42 144.5 0.5 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 KDO17142.1 - 6.5e-31 106.0 12.0 8e-09 35.7 0.1 8.8 8 0 0 8 8 8 7 PQQ-like domain PQQ_2 PF13360.6 KDO17142.1 - 7e-21 74.9 0.3 2e-11 43.9 0.1 3.3 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KDO17142.1 - 1.6e-13 49.8 1.0 7.4e-05 22.5 0.1 4.7 4 0 0 4 4 4 3 PQQ enzyme repeat PP-binding PF00550.25 KDO17142.1 - 6.5e-06 26.4 0.1 1.3e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site SUKH-4 PF14435.6 KDO17142.1 - 0.057 13.5 5.8 0.69 9.9 0.3 3.9 3 2 1 4 4 4 0 SUKH-4 immunity protein DHFR_1 PF00186.19 KDO17143.1 - 6.8e-37 126.6 0.0 7.8e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase NAD_binding_6 PF08030.12 KDO17144.1 - 8.8e-10 38.9 0.0 2.9e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KDO17144.1 - 7.1e-09 36.3 0.0 1e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KDO17146.1 - 2.8e-10 40.5 0.0 1.5e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KDO17146.1 - 2.6e-06 28.0 0.0 6.1e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KDO17146.1 - 8.9e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Peptidase_C26 PF07722.13 KDO17147.1 - 4.7e-18 65.7 0.0 2e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KDO17147.1 - 1.2e-09 38.2 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF2929 PF11151.8 KDO17148.1 - 0.086 13.1 1.8 0.21 11.9 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2929) Ank_2 PF12796.7 KDO17150.1 - 2e-29 102.0 6.8 1.7e-14 54.2 0.5 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17150.1 - 2.3e-22 79.1 5.7 2.2e-08 34.5 0.3 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO17150.1 - 2.5e-18 65.6 20.4 0.00022 21.6 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KDO17150.1 - 7.7e-17 59.7 8.3 0.041 14.4 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KDO17150.1 - 8.2e-17 61.1 18.2 6.9e-08 32.6 1.1 5.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) MlaD PF02470.20 KDO17152.1 - 0.088 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 MlaD protein HMG14_17 PF01101.18 KDO17153.1 - 0.12 13.4 12.8 0.15 13.0 12.8 1.1 1 0 0 1 1 1 0 HMG14 and HMG17 DUF5338 PF17273.2 KDO17154.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Helo_like_N PF17111.5 KDO17155.1 - 0.035 13.5 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF5054 PF16477.5 KDO17155.1 - 0.17 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) Glyco_hydro_18 PF00704.28 KDO17158.1 - 0.00017 21.5 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_tran PF00005.27 KDO17159.1 - 1.4e-11 45.1 0.0 2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KDO17159.1 - 0.0037 17.7 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KDO17159.1 - 0.0051 16.1 0.1 0.011 15.0 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KDO17159.1 - 0.0085 15.8 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO17159.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KDO17159.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KDO17159.1 - 0.077 12.4 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO17159.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KDO17159.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 KDO17159.1 - 0.14 12.2 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Cyclin_C_2 PF16899.5 KDO17161.1 - 0.034 14.5 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain Dabb PF07876.12 KDO17162.1 - 5.4e-20 71.8 0.0 6.1e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain LAMTOR5 PF16672.5 KDO17164.1 - 2.8e-09 36.8 0.0 3.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 MatE PF01554.18 KDO17166.1 - 7.1e-12 45.3 6.2 7.1e-12 45.3 6.2 1.5 2 0 0 2 2 2 1 MatE YlaH PF14036.6 KDO17166.1 - 0.038 14.3 1.8 0.33 11.3 0.5 2.4 2 0 0 2 2 2 0 YlaH-like protein ORC5_C PF14630.6 KDO17167.1 - 0.049 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Macoilin PF09726.9 KDO17168.1 - 0.0014 17.3 7.0 0.0015 17.2 7.0 1.1 1 0 0 1 1 1 1 Macoilin family SNAPc19 PF15497.6 KDO17168.1 - 0.0022 18.4 1.3 0.0071 16.8 1.3 1.8 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Tmemb_cc2 PF10267.9 KDO17168.1 - 0.0099 15.1 8.5 0.0061 15.8 7.3 1.4 1 1 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF1690 PF07956.11 KDO17168.1 - 0.014 15.8 2.6 0.022 15.2 2.6 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2046 PF09755.9 KDO17168.1 - 0.054 12.7 1.0 0.077 12.2 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Serine_rich PF08824.10 KDO17168.1 - 0.14 12.2 2.6 0.25 11.3 1.9 1.5 1 1 0 1 1 1 0 Serine rich protein interaction domain DUF948 PF06103.11 KDO17168.1 - 0.3 11.4 3.1 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 KDO17168.1 - 0.46 10.3 5.5 0.71 9.7 5.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 PP1c_bdg PF10488.9 KDO17168.1 - 5.8 6.3 13.6 0.47 9.9 9.3 1.4 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region Glyco_hydro_18 PF00704.28 KDO17169.1 - 9.6e-06 25.5 0.0 5.1e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 Ku_C PF03730.14 KDO17171.1 - 0.051 14.3 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm PDZ_1 PF12812.7 KDO17172.1 - 2e-24 85.4 0.0 6.6e-17 61.3 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.6 KDO17172.1 - 9e-14 51.6 0.0 0.011 16.0 0.0 4.5 4 0 0 4 4 4 4 PDZ domain Trypsin_2 PF13365.6 KDO17172.1 - 1.1e-12 49.1 3.9 1.3e-07 32.7 0.1 3.5 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KDO17172.1 - 1.4e-12 47.2 0.3 0.019 14.8 0.0 4.8 5 0 0 5 5 5 4 PDZ domain PDZ PF00595.24 KDO17172.1 - 1.3e-09 38.3 0.0 0.00057 20.2 0.0 4.1 4 0 0 4 4 4 2 PDZ domain Peptidase_S46 PF10459.9 KDO17172.1 - 0.0029 16.3 0.3 0.004 15.9 0.3 1.1 1 0 0 1 1 1 1 Peptidase S46 DUF31 PF01732.16 KDO17172.1 - 0.3 10.6 0.3 0.42 10.1 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 KDO17172.1 - 0.38 10.6 1.9 0.59 10.0 1.0 1.7 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease UreE_N PF02814.15 KDO17172.1 - 0.47 10.1 2.5 1.8 8.2 0.2 2.9 4 0 0 4 4 4 0 UreE urease accessory protein, N-terminal domain Vps62 PF06101.11 KDO17174.1 - 0.083 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 SLED PF12140.8 KDO17174.1 - 0.11 13.0 1.1 2.1 8.9 0.1 2.9 3 1 0 3 3 3 0 SLED domain LRR_6 PF13516.6 KDO17174.1 - 0.41 10.8 4.5 1.5 9.0 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat HSP70 PF00012.20 KDO17175.1 - 6.6e-27 94.0 0.0 7.3e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Kelch_3 PF13415.6 KDO17176.1 - 1.7e-08 34.6 0.0 1.7e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO17176.1 - 7.2e-05 22.7 0.0 0.69 10.0 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KDO17176.1 - 0.0014 18.6 0.0 0.2 11.7 0.0 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain MARVEL PF01284.23 KDO17177.1 - 0.63 10.1 15.9 1.5 8.8 15.9 1.7 1 1 0 1 1 1 0 Membrane-associating domain Ank_2 PF12796.7 KDO17178.1 - 0.00016 22.2 2.5 0.03 14.9 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17178.1 - 0.27 11.9 8.4 8.4 7.1 0.1 3.9 3 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17178.1 - 5.8 7.8 5.7 19 6.2 0.0 4.0 5 1 0 5 5 5 0 Ankyrin repeat Pkinase PF00069.25 KDO17179.1 - 3e-22 79.2 0.0 4.1e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17179.1 - 2.7e-20 72.8 0.0 3.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO17179.1 - 8.6e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DEP PF00610.21 KDO17180.1 - 4.6e-09 36.2 0.0 9.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EMP70 PF02990.16 KDO17180.1 - 0.036 12.7 4.9 0.047 12.4 4.9 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Pox_A30L_A26L PF06086.12 KDO17180.1 - 0.077 12.7 0.2 0.64 9.7 0.0 2.3 2 1 1 3 3 3 0 Orthopoxvirus A26L/A30L protein VPS11_C PF12451.8 KDO17183.1 - 0.069 13.4 1.5 0.069 13.4 1.5 2.0 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DNA_binding_2 PF13724.6 KDO17183.1 - 0.26 11.7 1.7 0.27 11.6 0.2 1.8 1 1 1 2 2 2 0 DNA-binding domain FliT PF05400.13 KDO17183.1 - 0.4 11.5 10.7 0.19 12.6 0.6 2.5 1 1 1 2 2 2 0 Flagellar protein FliT Pkinase_Tyr PF07714.17 KDO17184.1 - 2.9e-40 138.2 0.0 3.2e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17184.1 - 2.8e-38 131.8 0.0 3.6e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO17184.1 - 0.0089 16.0 0.0 0.063 13.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CxC1 PF18802.1 KDO17185.1 - 0.22 11.7 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases FYVE PF01363.21 KDO17186.1 - 0.01 15.9 1.1 0.017 15.2 1.1 1.3 1 0 0 1 1 1 0 FYVE zinc finger Zip PF02535.22 KDO17187.1 - 1.9e-31 109.5 11.5 2.1e-31 109.4 11.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_5_2 PF16079.5 KDO17187.1 - 1.2 9.6 8.2 1.1 9.6 0.9 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V MatE PF01554.18 KDO17189.1 - 3.3e-42 143.9 29.5 6.9e-24 84.3 8.3 2.3 2 0 0 2 2 2 2 MatE DUF5102 PF17104.5 KDO17191.1 - 0.047 13.7 3.2 0.06 13.4 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) DUF3108 PF11306.8 KDO17191.1 - 0.082 12.9 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) HTH_41 PF14502.6 KDO17192.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain M16C_assoc PF08367.11 KDO17193.1 - 0.1 11.7 0.8 0.12 11.5 0.8 1.1 1 0 0 1 1 1 0 Peptidase M16C associated hNIFK_binding PF12196.8 KDO17194.1 - 0.21 11.1 1.1 0.74 9.4 0.1 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK p450 PF00067.22 KDO17196.1 - 7.9e-62 209.5 0.0 1.3e-61 208.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DAGAT PF03982.13 KDO17198.1 - 3.5e-14 52.4 0.0 4.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ank_2 PF12796.7 KDO17199.1 - 2.4e-81 268.4 12.1 2.2e-17 63.4 0.0 6.9 1 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17199.1 - 9.4e-63 200.7 19.0 0.00023 21.3 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 KDO17199.1 - 3e-62 206.3 16.5 3.8e-09 36.9 0.0 10.8 4 2 7 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17199.1 - 4e-62 205.5 30.8 4e-09 36.6 0.0 14.5 1 1 14 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.30 KDO17199.1 - 1e-54 180.7 33.9 1.6e-05 25.1 0.0 15.0 15 1 1 16 16 16 14 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO17201.1 - 9.4e-17 61.1 0.0 3.4e-13 49.5 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO17201.1 - 1.4e-09 37.8 0.0 4.9e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain PLATZ PF04640.14 KDO17206.1 - 0.023 15.3 0.6 0.038 14.6 0.2 1.5 2 0 0 2 2 2 0 PLATZ transcription factor PLATZ PF04640.14 KDO17207.1 - 0.014 16.0 0.9 0.024 15.3 0.9 1.4 1 0 0 1 1 1 0 PLATZ transcription factor zf-MYND PF01753.18 KDO17207.1 - 0.34 11.0 4.6 0.66 10.1 4.6 1.5 1 1 0 1 1 1 0 MYND finger DUF1833 PF08875.11 KDO17208.1 - 0.012 15.2 0.1 0.019 14.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1833) TPP_enzyme_C PF02775.21 KDO17209.1 - 0.044 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Corona_7 PF02398.16 KDO17209.1 - 0.087 13.4 0.1 9.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Coronavirus protein 7 BBS1 PF14779.6 KDO17211.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Sugar_tr PF00083.24 KDO17212.1 - 6.1e-33 114.4 33.0 5.4e-32 111.2 33.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO17212.1 - 5.2e-19 68.4 43.5 1.5e-15 57.0 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO17212.1 - 0.00026 19.6 1.0 0.00026 19.6 1.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YqhR PF11085.8 KDO17212.1 - 1.6 8.7 9.6 2.5 8.0 2.6 2.6 2 0 0 2 2 2 0 Conserved membrane protein YqhR zf-MYND PF01753.18 KDO17213.1 - 3.1e-08 33.6 9.7 3.1e-08 33.6 9.7 3.8 3 2 1 4 4 4 1 MYND finger MukF_C PF17193.4 KDO17214.1 - 0.031 14.4 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 MukF C-terminal domain Mito_carr PF00153.27 KDO17215.1 - 1.9e-19 69.4 0.0 2e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Pkinase_Tyr PF07714.17 KDO17217.1 - 6.6e-50 169.8 0.0 8.1e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17217.1 - 1.9e-48 165.1 0.0 2.7e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO17217.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SKG6 PF08693.10 KDO17217.1 - 0.0042 16.5 0.2 0.0092 15.4 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 KDO17217.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO17217.1 - 0.022 14.7 0.1 0.053 13.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO17217.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO17217.1 - 0.15 11.0 0.0 0.32 9.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Wbp11 PF09429.10 KDO17218.1 - 9.4e-10 38.8 9.4 1e-09 38.6 9.4 1.0 1 0 0 1 1 1 1 WW domain binding protein 11 ABC2_membrane PF01061.24 KDO17219.1 - 9.7e-39 133.0 22.7 1.6e-38 132.2 22.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO17219.1 - 2.9e-23 82.9 0.0 4.3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO17219.1 - 1.4e-08 34.9 0.0 0.00029 20.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KDO17219.1 - 3.1e-05 23.2 22.8 3.1e-05 23.2 22.8 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KDO17219.1 - 0.0025 17.7 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO17219.1 - 0.051 13.3 0.4 0.1 12.3 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 KDO17219.1 - 3.8 6.7 13.1 8.6 5.5 13.0 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 KDO17220.1 - 1.7e-06 28.6 0.1 2.5e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KDO17220.1 - 6.4e-05 22.9 0.1 6.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO17220.1 - 0.00018 21.2 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO17220.1 - 0.0031 17.1 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO17220.1 - 0.0036 17.7 0.0 0.0044 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KDO17220.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KDO17220.1 - 0.02 14.7 0.2 0.032 14.1 0.1 1.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KDO17220.1 - 0.043 14.0 0.3 0.84 9.9 0.1 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KDO17220.1 - 0.054 13.8 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KDO17220.1 - 0.069 12.5 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SMC_N PF02463.19 KDO17220.1 - 0.077 12.4 0.1 0.096 12.1 0.1 1.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain CPT PF07931.12 KDO17220.1 - 0.088 12.6 0.1 0.77 9.6 0.1 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KDO17220.1 - 0.11 12.7 0.2 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 KDO17220.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Guanylate kinase AAA_35 PF14516.6 KDO17220.1 - 0.24 10.2 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PIG-L PF02585.17 KDO17221.1 - 0.00046 20.8 1.3 0.0015 19.2 1.3 1.8 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase GSCFA PF08885.11 KDO17221.1 - 0.059 13.0 0.1 0.092 12.4 0.1 1.2 1 0 0 1 1 1 0 GSCFA family SAP PF02037.27 KDO17223.1 - 1.1e-11 44.2 0.4 2e-11 43.4 0.4 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KDO17223.1 - 0.0085 15.8 0.1 0.0085 15.8 0.1 2.8 3 0 0 3 3 3 1 HeH/LEM domain Chorion_2 PF03964.15 KDO17223.1 - 0.97 10.3 9.0 0.12 13.2 1.3 2.5 1 1 1 2 2 2 0 Chorion family 2 Acetyltransf_1 PF00583.25 KDO17224.1 - 2.2e-07 31.1 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO17224.1 - 9.4e-06 25.6 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO17224.1 - 0.0021 18.5 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2710 PF10921.8 KDO17224.1 - 0.085 13.3 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) HECT PF00632.25 KDO17226.1 - 3.3e-68 230.4 0.0 4.3e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DNA_ligase_A_N PF04675.14 KDO17226.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA ligase N terminus ABC_tran PF00005.27 KDO17228.1 - 3.5e-45 153.9 0.0 9.5e-32 110.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO17228.1 - 3.7e-45 154.7 9.8 4.7e-45 154.4 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO17228.1 - 1e-09 38.2 2.4 0.0028 17.1 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO17228.1 - 0.0015 18.9 0.9 0.0079 16.6 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KDO17228.1 - 0.0023 18.1 4.3 4.7 7.5 0.4 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KDO17228.1 - 0.0083 16.4 0.6 0.12 12.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KDO17228.1 - 0.011 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KDO17228.1 - 0.019 13.8 3.7 0.29 9.9 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KDO17228.1 - 0.082 12.2 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 KDO17228.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KDO17228.1 - 0.15 11.8 4.1 0.25 11.0 2.0 2.5 2 1 0 2 2 2 0 AAA domain Ank_4 PF13637.6 KDO17229.1 - 2.2e-37 126.9 13.8 3.6e-14 52.9 0.2 7.3 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17229.1 - 7.4e-36 122.6 3.9 1.3e-11 44.9 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17229.1 - 2.2e-28 95.1 4.9 0.0001 22.4 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KDO17229.1 - 8.3e-28 96.1 15.4 1.5e-10 41.1 0.2 7.1 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO17229.1 - 3.6e-27 93.6 9.1 4.1e-06 27.0 0.1 8.4 8 0 0 8 8 8 6 Ankyrin repeat DP PF08781.10 KDO17230.1 - 1.8e-36 125.0 1.5 4.6e-36 123.8 1.5 1.7 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KDO17230.1 - 1.1e-24 86.2 0.1 1.1e-24 86.2 0.1 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain PBP1_TM PF14812.6 KDO17230.1 - 0.0014 18.9 2.1 0.0049 17.2 2.1 2.0 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KDO17230.1 - 0.035 13.9 10.2 0.14 11.9 4.9 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KDO17230.1 - 0.27 10.5 4.4 0.46 9.8 4.4 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KDO17230.1 - 0.47 10.9 10.1 1 9.8 10.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KDO17230.1 - 0.54 9.9 4.6 0.24 11.1 0.9 2.2 2 0 0 2 2 2 0 FAM176 family NGF PF00243.18 KDO17232.1 - 0.029 14.6 0.0 0.03 14.6 0.0 1.0 1 0 0 1 1 1 0 Nerve growth factor family RNA_pol_Rpb2_3 PF04565.16 KDO17232.1 - 0.13 12.4 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 ABC_tran PF00005.27 KDO17235.1 - 0.0028 18.2 0.0 0.012 16.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KDO17235.1 - 0.07 12.6 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Pkinase PF00069.25 KDO17236.1 - 1.9e-35 122.5 0.0 2.6e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17236.1 - 1.7e-32 112.8 0.0 2.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17236.1 - 2.4e-05 23.8 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO17236.1 - 0.0029 16.4 0.0 0.004 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO17236.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO17236.1 - 0.048 13.6 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO17237.1 - 2.1e-14 53.6 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KDO17237.1 - 7.3e-14 51.9 0.7 3.8e-10 40.1 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17237.1 - 1.5e-12 47.9 0.3 1.5e-12 47.9 0.3 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KDO17237.1 - 2.3e-12 46.8 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KDO17237.1 - 8.1e-11 42.0 5.9 0.00016 21.9 1.3 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17237.1 - 9.1e-11 41.0 1.5 0.0027 18.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KDO17237.1 - 1e-07 32.1 10.9 0.0016 18.8 0.1 4.0 5 0 0 5 5 5 2 Ankyrin repeat AAA_12 PF13087.6 KDO17238.1 - 1.5e-33 116.1 0.1 7.8e-33 113.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KDO17238.1 - 5.3e-28 98.5 0.6 1.4e-13 51.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KDO17238.1 - 3.9e-06 26.7 1.4 0.0027 17.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 KDO17238.1 - 0.00017 21.7 0.0 0.0018 18.3 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KDO17238.1 - 0.0069 16.7 2.2 0.022 15.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KDO17238.1 - 0.0084 16.5 0.5 0.085 13.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO17238.1 - 0.021 14.4 0.3 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KDO17238.1 - 0.061 12.8 0.1 0.29 10.6 0.0 2.2 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain Med26 PF08711.11 KDO17238.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain AAA_22 PF13401.6 KDO17238.1 - 0.15 12.4 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO17238.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KH_1 PF00013.29 KDO17239.1 - 0.001 18.8 0.1 0.035 13.9 0.0 2.4 2 1 0 2 2 2 2 KH domain Dynein_light PF01221.18 KDO17240.1 - 2.2e-22 79.2 0.1 2.6e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Lipocalin_5 PF13924.6 KDO17240.1 - 0.039 13.7 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Lipocalin-like domain fn3 PF00041.21 KDO17241.1 - 7.3e-09 35.9 0.1 1.3e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Ank_5 PF13857.6 KDO17241.1 - 7.1e-06 26.2 0.0 2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17241.1 - 0.001 19.6 0.1 0.0049 17.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17241.1 - 0.0015 18.8 0.0 0.0079 16.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KDO17241.1 - 0.019 15.6 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KDO17241.1 - 0.059 13.8 0.0 0.88 10.1 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat FYVE PF01363.21 KDO17244.1 - 2.6e-11 43.5 24.7 1.2e-10 41.4 24.7 2.3 1 1 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO17244.1 - 3.7e-10 40.0 7.3 3.7e-10 40.0 7.3 3.3 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO17244.1 - 7e-08 32.2 7.6 7e-08 32.2 7.6 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO17244.1 - 6.6e-06 26.3 6.5 6.6e-06 26.3 6.5 3.4 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO17244.1 - 1.1e-05 25.0 2.2 1.1e-05 25.0 2.2 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO17244.1 - 2.6e-05 24.0 5.2 2.6e-05 24.0 5.2 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO17244.1 - 0.00018 21.0 3.7 0.00018 21.0 3.7 2.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KDO17244.1 - 0.0013 18.6 7.4 0.0013 18.6 7.4 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO17244.1 - 0.011 15.7 2.0 0.011 15.7 2.0 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.16 KDO17244.1 - 0.016 15.4 8.8 0.04 14.1 8.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF983 PF06170.12 KDO17244.1 - 1.2 9.6 7.6 9.2 6.7 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF983) zinc_ribbon_16 PF17034.5 KDO17244.1 - 2.9 8.1 14.4 0.33 11.2 3.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon like family zinc_ribbon_9 PF14369.6 KDO17244.1 - 10 6.5 14.1 12 6.3 0.4 4.0 3 0 0 3 3 3 0 zinc-ribbon PPI_Ypi1 PF07491.11 KDO17245.1 - 1.1e-07 31.5 12.2 1.1e-07 31.5 12.2 2.1 1 1 1 2 2 2 1 Protein phosphatase inhibitor RhoGEF67_u1 PF16615.5 KDO17245.1 - 0.022 15.3 2.9 0.022 15.3 2.9 1.6 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 Myb_DNA-binding PF00249.31 KDO17247.1 - 8.4e-10 38.7 0.3 1.3e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO17247.1 - 0.00047 20.3 0.3 0.00083 19.6 0.3 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Cupin_4 PF08007.12 KDO17248.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein CRA_rpt PF07046.11 KDO17248.1 - 0.18 12.0 5.7 1.7 8.9 5.7 2.2 1 1 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat SMK-1 PF04802.15 KDO17250.1 - 4.1e-36 124.6 0.1 1.1e-35 123.2 0.1 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF3829 PF12889.7 KDO17251.1 - 0.0085 15.6 0.7 0.01 15.3 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) Exonuc_VII_L PF02601.15 KDO17251.1 - 0.013 15.1 3.2 0.016 14.8 3.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Casc1 PF12366.8 KDO17251.1 - 0.063 12.8 0.6 0.074 12.6 0.6 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Ribosomal_L14e PF01929.17 KDO17251.1 - 0.22 12.0 6.3 0.28 11.7 5.9 1.4 1 1 0 1 1 1 0 Ribosomal protein L14 Aa_trans PF01490.18 KDO17252.1 - 5.3e-28 97.9 12.2 5.9e-28 97.7 12.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_2 PF12796.7 KDO17254.1 - 6.8e-07 29.8 1.6 0.00061 20.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17254.1 - 7.4e-05 23.2 0.3 0.035 14.7 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17254.1 - 0.012 15.9 2.7 21 5.6 0.0 4.0 2 2 2 4 4 4 0 Ankyrin repeats (many copies) Erythro-docking PF09277.11 KDO17254.1 - 0.033 14.1 0.2 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Erythronolide synthase, docking FolB PF02152.18 KDO17254.1 - 0.14 12.8 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase Ank_3 PF13606.6 KDO17254.1 - 0.16 12.6 0.6 1.6e+02 3.4 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Thioredoxin PF00085.20 KDO17256.1 - 2.9e-13 49.7 0.0 3.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KDO17256.1 - 7.4e-06 25.9 0.0 9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 KDO17256.1 - 0.00029 20.8 0.0 0.00057 19.8 0.0 1.3 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 KDO17256.1 - 0.00057 19.3 0.0 0.00069 19.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KDO17256.1 - 0.0008 19.8 0.1 0.008 16.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KDO17256.1 - 0.0027 17.7 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KDO17256.1 - 0.032 14.3 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain DIM1 PF02966.16 KDO17256.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 AMP-binding PF00501.28 KDO17257.1 - 9.1e-50 169.5 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO17257.1 - 0.0044 18.0 0.2 0.0097 16.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KDO17259.1 - 4.5e-32 111.4 0.0 6.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO17259.1 - 3.4e-20 72.8 0.2 5e-20 72.3 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO17259.1 - 1.2e-07 31.4 0.7 1.7e-06 27.6 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO17259.1 - 4.1e-05 24.0 2.1 6.3e-05 23.4 0.6 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KDO17259.1 - 8.3e-05 22.4 1.1 0.0002 21.1 1.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO17259.1 - 9.6e-05 22.0 1.2 0.09 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KDO17259.1 - 0.0003 21.1 1.3 0.0024 18.1 1.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KDO17259.1 - 0.00031 20.4 0.4 0.00081 19.1 0.4 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO17259.1 - 0.0083 16.0 0.9 0.66 9.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO17259.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KDO17259.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KDO17259.1 - 0.019 15.2 0.2 0.24 11.7 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO17259.1 - 0.02 15.1 0.2 0.054 13.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO17259.1 - 0.022 14.5 0.1 0.87 9.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KDO17259.1 - 0.026 14.5 0.1 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KDO17259.1 - 0.033 14.6 0.2 0.34 11.3 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KDO17259.1 - 0.044 12.6 0.2 0.12 11.1 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DEAD PF00270.29 KDO17259.1 - 0.11 12.2 0.5 0.51 10.1 0.5 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KDO17259.1 - 0.13 12.3 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KDO17259.1 - 0.14 12.0 0.3 2.8 7.8 0.1 2.2 2 0 0 2 2 2 0 NTPase Nop53 PF07767.11 KDO17260.1 - 0.032 13.6 7.6 0.046 13.1 7.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop25 PF09805.9 KDO17260.1 - 0.41 11.1 9.9 0.64 10.5 9.9 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) FYDLN_acid PF09538.10 KDO17260.1 - 0.51 11.0 12.4 1.2 9.9 12.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 KDO17260.1 - 0.6 8.3 11.4 0.9 7.7 11.4 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KDO17260.1 - 0.77 7.8 10.2 0.83 7.7 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi APG6_N PF17675.1 KDO17260.1 - 1.1 9.9 7.3 1.8 9.1 7.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2457 PF10446.9 KDO17260.1 - 1.9 7.5 12.8 2.5 7.1 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 KDO17260.1 - 5.6 5.4 6.2 7 5.1 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.8 KDO17260.1 - 9.5 6.4 15.3 31 4.7 14.3 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 KDO17260.1 - 9.7 5.2 9.9 13 4.8 9.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Peptidase_C97 PF05903.14 KDO17263.1 - 1.2e-33 116.0 0.0 1.6e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 KDO17263.1 - 0.01 16.2 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) CAP PF00188.26 KDO17265.1 - 1.6e-11 45.2 4.4 2.2e-11 44.7 4.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sugarporin_N PF11471.8 KDO17266.1 - 0.038 14.0 0.2 0.069 13.1 0.2 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Plasmid_RAQPRD PF09686.10 KDO17266.1 - 0.18 12.1 1.6 0.58 10.4 1.6 1.9 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) CCDC106 PF15794.5 KDO17266.1 - 0.2 11.3 0.8 0.36 10.5 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4140 PF13600.6 KDO17266.1 - 0.4 11.2 2.3 3.3 8.2 1.0 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GTP_EFTU PF00009.27 KDO17267.1 - 4.1e-28 98.3 0.4 5.2e-28 97.9 0.4 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ChaC PF04752.12 KDO17267.1 - 5.3e-17 62.4 0.0 7.9e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein MMR_HSR1 PF01926.23 KDO17267.1 - 7.8e-05 22.7 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KDO17267.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Septin DSPc PF00782.20 KDO17267.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AIG1 PF04548.16 KDO17267.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 KDO17267.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KDO17267.1 - 0.099 12.2 0.0 0.85 9.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B CH_2 PF06294.11 KDO17268.1 - 2.2e-18 66.1 0.0 2.5e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 KDO17268.1 - 0.066 13.4 0.0 0.066 13.4 0.0 1.2 1 1 0 1 1 1 0 Calponin homology (CH) domain Methyltr_RsmB-F PF01189.17 KDO17269.1 - 3.5e-40 137.8 0.0 3.7e-39 134.5 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F zf-CCHC_2 PF13696.6 KDO17269.1 - 2.3e-08 33.7 4.9 4.3e-08 32.8 4.9 1.5 1 0 0 1 1 1 1 Zinc knuckle FtsJ PF01728.19 KDO17269.1 - 0.004 17.3 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-CCHC PF00098.23 KDO17269.1 - 0.013 15.6 0.6 0.025 14.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Hormone_4 PF00220.17 KDO17269.1 - 0.32 11.1 1.4 0.73 9.9 1.4 1.5 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Methyltransf_7 PF03492.15 KDO17270.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DivIVA PF05103.13 KDO17271.1 - 0.0087 16.1 1.0 3.7 7.6 0.1 2.4 2 0 0 2 2 2 2 DivIVA protein DUF2046 PF09755.9 KDO17271.1 - 0.018 14.3 3.5 0.22 10.7 3.5 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) bMG3 PF11974.8 KDO17271.1 - 0.07 13.2 0.2 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain Cnn_1N PF07989.11 KDO17271.1 - 0.12 12.5 3.1 1.9 8.7 0.3 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 HIP1_clath_bdg PF16515.5 KDO17271.1 - 0.25 12.0 3.8 0.32 11.6 0.2 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 KDO17271.1 - 0.86 9.4 4.4 0.98 9.2 1.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Methyltransf_PK PF05891.12 KDO17272.1 - 1.2e-73 247.3 0.0 1.5e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KDO17272.1 - 3.3e-10 40.6 0.0 6.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO17272.1 - 5.8e-10 39.7 0.0 9.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO17272.1 - 1.9e-07 31.7 0.0 3.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KDO17272.1 - 5.5e-07 29.1 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KDO17272.1 - 7e-07 29.2 0.0 1.4e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO17272.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fer4_5 PF12801.7 KDO17272.1 - 0.09 12.7 0.5 0.17 11.9 0.5 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Methyltransf_3 PF01596.17 KDO17272.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase HU-CCDC81_euk_2 PF18289.1 KDO17273.1 - 3.9e-15 55.8 0.1 6.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 KDO17273.1 - 4.2e-10 39.7 0.0 7.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 SNARE PF05739.19 KDO17277.1 - 2e-12 46.9 0.2 2e-12 46.9 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KDO17277.1 - 2.1e-07 30.8 9.9 0.00069 19.4 0.4 2.5 3 0 0 3 3 3 2 Syntaxin V-ATPase_G_2 PF16999.5 KDO17277.1 - 0.0045 17.4 2.1 0.0045 17.4 2.1 2.4 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit MCPsignal PF00015.21 KDO17277.1 - 0.025 14.4 0.6 0.025 14.4 0.6 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GTA_holin_3TM PF11351.8 KDO17277.1 - 0.091 13.3 0.2 0.091 13.3 0.2 2.7 1 1 3 4 4 4 0 Holin of 3TMs, for gene-transfer release OmpH PF03938.14 KDO17277.1 - 6.5 7.1 12.8 17 5.8 12.6 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-M PF11111.8 KDO17281.1 - 0.019 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) SR-25 PF10500.9 KDO17281.1 - 2.4 7.7 7.8 3.2 7.3 7.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Helicase_C PF00271.31 KDO17282.1 - 3.6e-30 104.6 0.0 6.6e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO17282.1 - 1.6e-05 24.8 0.1 3.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PTA_PTB PF01515.19 KDO17282.1 - 0.057 12.7 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase AMP_N PF05195.16 KDO17282.1 - 0.13 12.0 0.0 2.5 7.9 0.0 2.6 3 1 0 3 3 3 0 Aminopeptidase P, N-terminal domain ABC_membrane PF00664.23 KDO17284.1 - 6.8e-18 65.3 12.6 9.4e-18 64.8 12.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO17284.1 - 1.1e-12 48.6 0.0 2.3e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 KDO17284.1 - 4e-05 23.7 0.0 6.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin family AAA_25 PF13481.6 KDO17284.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KDO17284.1 - 0.0031 17.6 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 KDO17284.1 - 0.0069 15.8 0.4 0.048 13.1 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO17284.1 - 0.0099 15.8 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO17284.1 - 0.012 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO17284.1 - 0.014 15.8 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 KDO17284.1 - 0.014 14.5 0.0 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 KDO17284.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO17284.1 - 0.094 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KDO17284.1 - 0.18 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KDO17284.1 - 0.26 11.0 0.0 0.35 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain TTL PF03133.15 KDO17285.1 - 6.9e-72 242.1 0.0 1.3e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO17285.1 - 1.2e-06 28.0 3.2 7.7e-06 25.3 0.0 3.2 3 1 1 4 4 4 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO17285.1 - 0.064 12.5 0.0 0.89 8.7 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KDO17285.1 - 0.15 12.1 0.0 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain CobD_Cbib PF03186.13 KDO17286.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 CobD/Cbib protein COX6C PF02937.15 KDO17287.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Methyltransf_10 PF05971.12 KDO17289.1 - 1.2e-78 264.4 0.0 4.4e-77 259.4 0.0 2.0 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KDO17289.1 - 5.2e-08 32.6 0.0 7.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KDO17289.1 - 5.2e-05 22.8 0.0 7.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KDO17289.1 - 0.0003 20.7 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 KDO17289.1 - 0.0036 16.9 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase UPF0020 PF01170.18 KDO17289.1 - 0.0038 16.9 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KDO17289.1 - 0.0063 17.2 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO17289.1 - 0.074 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO17289.1 - 0.17 12.6 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KDO17289.1 - 0.19 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DcpS_C PF11969.8 KDO17294.1 - 2.1e-23 82.9 0.1 2.7e-23 82.6 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KDO17294.1 - 1.9e-11 44.6 2.6 5.7e-11 43.0 2.6 1.6 1 1 0 1 1 1 1 HIT domain Jacalin PF01419.17 KDO17295.1 - 1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain LGT PF01790.18 KDO17296.1 - 0.0006 19.1 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Sulf_transp PF04143.14 KDO17298.1 - 7.4e-12 45.4 23.7 7.4e-12 45.4 23.7 2.4 1 1 0 2 2 2 1 Sulphur transport Hol_Tox PF16935.5 KDO17298.1 - 0.32 11.1 4.4 0.56 10.3 0.2 3.1 4 0 0 4 4 4 0 Putative Holin-like Toxin (Hol-Tox) FYVE_2 PF02318.16 KDO17299.1 - 0.22 11.8 6.6 0.48 10.6 6.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 KDO17299.1 - 1.1 9.3 13.8 2.5 8.2 13.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain MCM_bind PF09739.9 KDO17300.1 - 0.13 10.7 0.2 0.43 9.0 0.0 1.7 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor ADH_zinc_N_2 PF13602.6 KDO17301.1 - 3.3e-11 44.3 0.0 3.3e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 KDO17302.1 - 4e-14 52.6 0.2 8.2e-14 51.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17302.1 - 2.4e-11 43.4 0.0 4.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Oberon_cc PF16312.5 KDO17302.1 - 0.096 12.6 12.8 0.16 11.9 12.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of Oberon SOGA PF11365.8 KDO17302.1 - 0.56 11.4 7.7 0.91 10.7 6.4 1.9 1 1 1 2 2 2 0 Protein SOGA Rtf2 PF04641.12 KDO17302.1 - 1.6 8.0 5.8 2.3 7.5 5.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger OmpH PF03938.14 KDO17302.1 - 2.3 8.6 10.2 4.6 7.6 10.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MYO10_CC PF16735.5 KDO17302.1 - 2.6 8.2 10.9 5 7.3 1.8 2.8 1 1 1 2 2 2 0 Unconventional myosin-X coiled coil domain YlqD PF11068.8 KDO17302.1 - 4.1 7.8 7.4 7.9 6.9 7.4 1.5 1 1 0 1 1 1 0 YlqD protein Pkinase_Tyr PF07714.17 KDO17303.1 - 2.4e-10 40.1 0.0 3e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17303.1 - 8.7e-09 35.1 0.0 2.8e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain CCDC144C PF14915.6 KDO17303.1 - 0.0034 16.6 3.6 0.0063 15.7 3.6 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Kdo PF06293.14 KDO17303.1 - 0.0069 15.8 0.5 0.013 14.9 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAM184 PF15665.5 KDO17303.1 - 0.058 13.2 3.6 0.098 12.4 3.6 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Pkinase PF00069.25 KDO17304.1 - 3.7e-18 65.8 0.0 6.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17304.1 - 6e-17 61.8 0.0 9.4e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17304.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_A_type_inc PF04508.12 KDO17304.1 - 0.0055 16.5 1.2 0.012 15.4 1.2 1.5 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Oberon_cc PF16312.5 KDO17304.1 - 0.0061 16.5 5.0 0.011 15.7 5.0 1.3 1 0 0 1 1 1 1 Coiled-coil region of Oberon Kdo PF06293.14 KDO17304.1 - 0.026 13.9 3.4 0.039 13.3 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO17304.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain AA_permease PF00324.21 KDO17306.1 - 9.4e-18 64.0 35.5 1.3e-17 63.5 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO17306.1 - 5.9e-14 51.7 36.5 8.8e-14 51.2 36.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO17307.1 - 2.4e-11 43.1 33.2 6.9e-10 38.3 16.3 2.3 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KDO17307.1 - 3.8e-11 42.2 16.1 3.8e-11 42.2 16.1 2.4 1 1 0 2 2 2 1 Amino acid permease DUF2516 PF10724.9 KDO17307.1 - 3.7 7.9 6.5 0.53 10.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) HrpB7 PF09486.10 KDO17308.1 - 0.042 14.2 0.6 0.088 13.2 0.2 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2066 PF09839.9 KDO17308.1 - 0.077 12.4 0.3 6.1 6.2 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) DUF4097 PF13349.6 KDO17309.1 - 1.1e-11 44.6 3.1 1.1e-11 44.6 3.1 2.1 1 1 1 2 2 2 1 Putative adhesin TF_Otx PF03529.13 KDO17309.1 - 0.016 15.6 2.8 0.016 15.6 2.8 1.9 2 0 0 2 2 2 0 Otx1 transcription factor LRR_4 PF12799.7 KDO17310.1 - 2.8e-13 49.8 6.1 8.8e-07 29.2 0.5 3.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO17310.1 - 3.5e-09 36.3 6.0 1.1e-05 25.1 0.4 2.9 3 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 KDO17310.1 - 9.5e-07 28.5 0.1 1.9e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KDO17310.1 - 0.00016 21.7 1.9 8.4 7.4 0.1 4.3 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 KDO17310.1 - 0.00028 20.7 2.1 1.1 9.4 0.3 3.7 4 0 0 4 4 4 2 Leucine Rich repeat Peptidase_C2 PF00648.21 KDO17311.1 - 2.3e-08 33.5 0.0 3.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease ATP_bind_1 PF03029.17 KDO17312.1 - 5.2e-73 245.8 0.1 1.6e-72 244.2 0.1 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Pkinase PF00069.25 KDO17312.1 - 2.1e-39 135.5 0.0 4.7e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO17312.1 - 1.5e-32 111.5 0.0 4.8e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO17312.1 - 1.9e-16 60.1 0.0 4.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17312.1 - 1.8e-06 27.5 0.0 3.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like CbiA PF01656.23 KDO17312.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KDO17312.1 - 0.031 13.3 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KDO17312.1 - 0.063 13.1 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop YrbL-PhoP_reg PF10707.9 KDO17312.1 - 0.093 12.2 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2633 PF11119.8 KDO17313.1 - 0.012 15.5 0.1 5.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) FliE PF02049.18 KDO17313.1 - 0.73 10.0 7.3 2.1 8.5 0.4 3.4 2 2 2 4 4 4 0 Flagellar hook-basal body complex protein FliE Mito_carr PF00153.27 KDO17315.1 - 2.3e-71 235.8 0.9 6e-27 93.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO17315.1 - 0.013 14.6 0.7 4.1 6.5 0.1 2.7 3 1 0 3 3 3 0 Gammaproteobacterial serine protease CRCB PF02537.15 KDO17315.1 - 0.04 14.2 0.8 0.91 9.9 0.2 2.3 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) DUF5518 PF17647.1 KDO17315.1 - 0.25 11.5 5.2 0.96 9.6 0.0 3.5 3 1 1 4 4 4 0 Family of unknown function (DUF5518) Mito_carr PF00153.27 KDO17316.1 - 7.3e-65 215.0 2.6 2.2e-26 91.6 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO17316.1 - 0.00017 20.9 0.3 0.11 11.6 0.0 2.9 2 1 0 3 3 3 2 Gammaproteobacterial serine protease Tim17 PF02466.19 KDO17316.1 - 0.006 16.9 1.1 0.13 12.6 0.4 2.7 2 2 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Transthyretin PF00576.21 KDO17317.1 - 0.062 14.0 0.0 0.07 13.8 0.0 1.0 1 0 0 1 1 1 0 HIUase/Transthyretin family Myb_DNA-binding PF00249.31 KDO17318.1 - 2.9e-07 30.6 2.4 0.00037 20.6 0.1 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO17318.1 - 6.2e-06 26.4 0.1 0.00016 21.9 0.0 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain DUF2016 PF09436.10 KDO17318.1 - 0.094 12.5 0.1 9.9 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) MCLC PF05934.11 KDO17319.1 - 0.78 8.4 5.6 0.91 8.2 5.6 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Lipoxygenase PF00305.19 KDO17323.1 - 3.3e-05 22.5 0.2 5.9e-05 21.7 0.2 1.4 1 1 0 1 1 1 1 Lipoxygenase Allene_ox_cyc PF06351.11 KDO17324.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Ribosomal_S7 PF00177.21 KDO17325.1 - 9.2e-13 48.1 0.4 1.1e-12 47.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Lipase_bact_N PF12262.8 KDO17325.1 - 0.065 12.6 0.0 0.073 12.4 0.0 1.0 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal DUF3138 PF11336.8 KDO17326.1 - 1.6 7.3 4.1 1.7 7.2 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_28 PF13521.6 KDO17327.1 - 2.4e-13 50.7 0.1 4.8e-13 49.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain SecE PF00584.20 KDO17329.1 - 6.7e-15 54.8 0.1 7.7e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ank_4 PF13637.6 KDO17330.1 - 2.8e-16 59.7 3.7 3.3e-09 37.1 0.3 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17330.1 - 6.1e-15 53.8 1.1 5.2e-07 29.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO17330.1 - 1.5e-12 47.3 4.8 5.3e-06 26.6 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO17330.1 - 9.6e-12 44.9 2.5 7e-07 29.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17330.1 - 1.5e-11 44.7 0.2 1.5e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) DegS PF05384.11 KDO17331.1 - 0.0032 17.0 2.8 0.0038 16.7 2.8 1.0 1 0 0 1 1 1 1 Sensor protein DegS Ste5_C PF12194.8 KDO17331.1 - 0.042 13.8 0.2 0.046 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein kinase Fus3-binding Phage_r1t_holin PF16945.5 KDO17332.1 - 0.02 15.0 3.0 0.02 15.0 3.0 3.9 2 1 2 4 4 4 0 Putative lactococcus lactis phage r1t holin RNase_T PF00929.24 KDO17333.1 - 6.4e-15 56.1 0.0 9.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KDO17333.1 - 0.0064 16.2 0.0 0.034 13.9 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease COG6 PF06419.11 KDO17334.1 - 0.0086 14.3 0.8 0.013 13.8 0.8 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PAG PF15347.6 KDO17334.1 - 0.029 13.4 0.4 0.035 13.1 0.4 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Apolipoprotein PF01442.18 KDO17334.1 - 0.032 14.1 0.5 0.032 14.1 0.5 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain CBP_GIL PF10995.8 KDO17339.1 - 0.053 12.2 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL YqaJ PF09588.10 KDO17340.1 - 0.00011 22.4 0.1 0.025 14.7 0.1 2.4 2 1 0 2 2 2 2 YqaJ-like viral recombinase domain Peptidase_S24 PF00717.23 KDO17341.1 - 2.1e-09 37.2 0.0 3.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KDO17341.1 - 1.3e-07 31.5 0.1 0.00016 21.5 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TRAPPC9-Trs120 PF08626.11 KDO17343.1 - 0.0062 14.0 0.0 0.0087 13.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Nucleoporin_FG PF13634.6 KDO17344.1 - 1.2 10.0 11.9 18 6.3 11.9 2.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region zf-CXXC PF02008.20 KDO17345.1 - 2.5 8.2 18.7 3.3 7.8 2.6 2.7 2 0 0 2 2 2 0 CXXC zinc finger domain MFS_1 PF07690.16 KDO17346.1 - 1.9e-22 79.7 46.2 1e-15 57.6 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1218 PF06749.12 KDO17346.1 - 0.0034 17.9 0.1 0.0034 17.9 0.1 3.3 3 2 0 3 3 3 1 Protein of unknown function (DUF1218) MFS_1_like PF12832.7 KDO17346.1 - 1.5 7.6 16.6 0.24 10.2 8.3 2.9 1 1 1 2 2 2 0 MFS_1 like family Disintegrin PF00200.23 KDO17347.1 - 1.6e-37 128.1 186.2 3.6e-05 24.5 12.6 12.7 9 6 0 9 9 9 9 Disintegrin ABC2_membrane PF01061.24 KDO17348.1 - 8e-09 35.2 8.5 4.3e-08 32.8 8.5 1.8 1 1 0 1 1 1 1 ABC-2 type transporter EXS PF03124.14 KDO17348.1 - 0.008 15.5 4.7 0.0084 15.5 4.7 1.0 1 0 0 1 1 1 1 EXS family TMEM135_C_rich PF15982.5 KDO17348.1 - 0.016 15.8 0.5 0.019 15.5 0.5 1.2 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF3021 PF11457.8 KDO17348.1 - 0.039 14.3 5.8 0.049 14.0 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Polysacc_synt_C PF14667.6 KDO17348.1 - 0.94 9.5 8.2 1.4 9.0 8.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Pkinase PF00069.25 KDO17349.1 - 1.9e-27 96.3 0.0 2.2e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17349.1 - 1.2e-25 90.3 0.0 1.3e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO17349.1 - 0.00026 19.9 0.4 0.00031 19.7 0.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO17349.1 - 0.00089 18.7 0.0 0.0011 18.4 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO17349.1 - 0.00091 18.6 0.3 0.0011 18.3 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nrap_D2 PF17403.2 KDO17349.1 - 0.094 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Glutaredoxin PF00462.24 KDO17350.1 - 1.1e-11 44.8 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Bac_GH3_C PF18034.1 KDO17350.1 - 0.047 13.4 0.0 0.063 13.0 0.0 1.3 1 1 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Methyltransf_16 PF10294.9 KDO17351.1 - 8.7e-26 90.7 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KDO17351.1 - 0.00013 22.6 0.1 0.0017 19.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO17351.1 - 0.00093 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO17351.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KDO17351.1 - 0.01 16.6 0.1 0.4 11.4 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 KDO17351.1 - 0.067 12.5 0.2 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Spt4 PF06093.13 KDO17354.1 - 1.1e-33 115.1 0.7 1.4e-33 114.8 0.7 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Sec61_beta PF03911.16 KDO17355.1 - 3.9e-20 71.6 0.1 5.1e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family Ank_2 PF12796.7 KDO17356.1 - 3e-46 155.9 3.7 3.7e-09 37.1 0.0 6.9 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17356.1 - 5.7e-38 128.8 11.5 1.5e-05 25.4 0.0 10.3 4 3 9 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17356.1 - 2.9e-32 107.1 7.3 0.0024 18.2 0.0 13.3 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 KDO17356.1 - 1.2e-31 108.3 12.0 0.00025 21.3 0.1 10.2 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO17356.1 - 3.7e-17 61.9 29.5 0.082 13.4 0.1 11.6 11 2 2 13 13 13 6 Ankyrin repeat MMACHC PF16690.5 KDO17357.1 - 0.037 13.7 0.0 0.04 13.5 0.0 1.0 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Use1 PF09753.9 KDO17358.1 - 0.00021 21.1 0.0 0.00026 20.8 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 EAV_GP5 PF15981.5 KDO17358.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.5 1 1 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus Use1 PF09753.9 KDO17359.1 - 0.045 13.5 0.0 0.05 13.3 0.0 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 CX9C PF16860.5 KDO17361.1 - 3.9e-05 23.6 0.2 4.8e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 KDO17361.1 - 0.0047 17.1 0.5 0.0056 16.9 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein zf-CCHC_6 PF15288.6 KDO17361.1 - 0.033 14.0 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle UPF0203 PF05254.12 KDO17361.1 - 0.065 13.5 0.8 0.51 10.6 0.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Sdh5 PF03937.16 KDO17362.1 - 3e-20 72.0 0.1 4.9e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Phage_int_SAM_5 PF13102.6 KDO17362.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain Tim17 PF02466.19 KDO17363.1 - 1.5e-08 35.0 3.5 1.9e-08 34.7 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KDO17363.1 - 0.065 13.6 4.8 0.17 12.3 3.7 2.0 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 RWP-RK PF02042.15 KDO17364.1 - 9.3e-08 31.9 4.0 1.5e-07 31.2 4.0 1.4 1 0 0 1 1 1 1 RWP-RK domain PAN_4 PF14295.6 KDO17367.1 - 6.2e-06 26.0 5.7 1.5e-05 24.8 5.7 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KDO17367.1 - 0.00024 21.0 0.3 0.00024 21.0 0.3 1.9 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 KDO17367.1 - 0.014 15.5 5.8 0.036 14.2 5.8 1.7 1 0 0 1 1 1 0 PAN-like domain TNFR_c6 PF00020.18 KDO17368.1 - 6.2e-10 39.3 59.1 4.7e-05 23.7 8.4 5.5 2 1 4 6 6 6 4 TNFR/NGFR cysteine-rich region TPD52 PF04201.15 KDO17369.1 - 0.022 14.4 0.9 0.022 14.4 0.9 5.6 3 2 2 5 5 5 0 Tumour protein D52 family Fez1 PF06818.15 KDO17369.1 - 0.024 15.1 79.2 0.079 13.4 10.4 4.6 2 1 2 4 4 4 0 Fez1 DUF1803 PF08820.10 KDO17369.1 - 0.029 14.4 0.4 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) Transglut_N PF00868.20 KDO17369.1 - 0.18 12.2 4.2 0.2 12.0 1.6 2.5 1 1 1 2 2 2 0 Transglutaminase family Ehrlichia_rpt PF09528.10 KDO17370.1 - 0.13 11.8 0.5 0.23 11.0 0.5 1.3 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Nramp PF01566.18 KDO17371.1 - 2.6e-71 240.5 3.6 4.6e-71 239.7 3.6 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein LRR_4 PF12799.7 KDO17373.1 - 3.5e-15 55.9 6.4 2.8e-07 30.7 0.4 3.9 1 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO17373.1 - 1.1e-10 41.1 15.2 5.4e-07 29.3 2.4 2.8 2 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KDO17373.1 - 2.3e-06 27.2 2.0 0.0015 18.1 0.2 2.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KDO17373.1 - 1.2e-05 24.9 13.3 0.31 11.2 0.2 5.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 KDO17373.1 - 1.3e-05 25.1 8.9 11 7.0 0.6 5.4 3 1 1 4 4 4 3 Leucine Rich Repeat zf-CCHC_2 PF13696.6 KDO17375.1 - 0.003 17.3 1.5 0.0048 16.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KDO17375.1 - 0.043 13.8 1.9 0.087 12.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 KDO17375.1 - 0.077 12.5 1.4 0.13 11.8 1.4 1.3 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC PF00098.23 KDO17375.1 - 0.24 11.5 2.8 0.43 10.8 2.8 1.4 1 0 0 1 1 1 0 Zinc knuckle PBP1_TM PF14812.6 KDO17375.1 - 0.47 10.9 3.4 0.15 12.4 0.6 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3425 PF11905.8 KDO17376.1 - 0.00025 21.0 0.1 0.0003 20.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF2011 PF09428.10 KDO17376.1 - 0.049 13.9 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) PAN_4 PF14295.6 KDO17377.1 - 1.7e-20 72.6 35.9 2.1e-06 27.5 5.9 4.7 4 1 0 4 4 4 4 PAN domain PAN_2 PF08276.11 KDO17377.1 - 4e-06 26.8 33.9 0.061 13.4 2.4 4.4 4 0 0 4 4 4 4 PAN-like domain Whib PF02467.16 KDO17377.1 - 0.13 12.9 14.0 13 6.5 0.3 4.2 4 0 0 4 4 4 0 Transcription factor WhiB PAN_3 PF08277.12 KDO17377.1 - 0.15 11.9 30.7 0.08 12.8 2.2 4.4 4 0 0 4 4 4 0 PAN-like domain TALPID3 PF15324.6 KDO17377.1 - 1.7 6.2 4.1 2.3 5.8 4.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Ank_2 PF12796.7 KDO17378.1 - 1e-21 77.3 0.1 9.8e-11 42.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO17378.1 - 1.2e-15 57.2 0.8 3.6e-05 24.0 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO17378.1 - 7.7e-13 48.7 0.1 1.5e-06 28.6 0.0 2.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17378.1 - 5.2e-11 41.8 0.0 0.00085 19.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KDO17378.1 - 7.5e-07 29.3 0.3 0.0043 17.3 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FTZ PF03867.14 KDO17379.1 - 0.093 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Kazal_2 PF07648.15 KDO17381.1 - 5.3e-10 39.3 26.6 8.8e-09 35.4 1.6 4.2 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO17381.1 - 0.0069 16.4 6.7 0.0069 16.4 6.7 3.7 1 1 2 3 3 3 1 Kazal-type serine protease inhibitor domain Sds3 PF08598.11 KDO17383.1 - 4.3e-05 23.6 2.9 0.00013 22.0 2.9 1.8 1 1 0 1 1 1 1 Sds3-like fn3_PAP PF17808.1 KDO17383.1 - 0.045 13.9 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Use1 PF09753.9 KDO17384.1 - 0.00029 20.7 0.3 0.00034 20.4 0.3 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2927 PF11150.8 KDO17384.1 - 0.0055 16.8 0.7 0.0067 16.5 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2927) Nnf1 PF03980.14 KDO17384.1 - 0.018 15.4 2.3 0.027 14.8 2.3 1.3 1 0 0 1 1 1 0 Nnf1 AdoHcyase PF05221.17 KDO17385.1 - 7e-37 127.2 0.0 7.4e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KDO17385.1 - 1.8e-26 93.2 0.1 2.5e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Na_Ala_symp PF01235.17 KDO17385.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family Cob_adeno_trans PF01923.18 KDO17385.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Ribosomal_L21p PF00829.21 KDO17386.1 - 1.9e-31 108.3 2.6 2.3e-31 108.1 2.6 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CBM9_1 PF06452.11 KDO17388.1 - 9.4e-12 45.2 0.1 1.3e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 KDO17388.1 - 4.7e-06 26.4 0.0 7.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate-binding family 9 DUF2689 PF10894.8 KDO17388.1 - 0.14 11.9 0.2 13 5.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2689) zf-RanBP PF00641.18 KDO17389.1 - 0.037 13.3 3.8 0.077 12.3 3.8 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KDO17389.1 - 0.58 9.6 3.7 2.2 7.7 3.7 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DivIC PF04977.15 KDO17390.1 - 0.65 9.8 4.4 1.5 8.6 4.4 1.6 1 0 0 1 1 1 0 Septum formation initiator PIP5K PF01504.18 KDO17392.1 - 2.3e-66 223.8 0.0 3.4e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 KDO17392.1 - 5.9e-07 29.0 8.6 9.8e-07 28.3 8.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KDO17392.1 - 3.1e-05 23.3 6.1 8e-05 21.9 5.9 1.8 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KDO17392.1 - 0.00028 20.3 9.1 0.00049 19.5 9.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KDO17392.1 - 0.012 15.0 5.3 0.018 14.4 5.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx BT1 PF03092.16 KDO17394.1 - 9.2e-12 43.9 9.9 1.1e-08 33.9 0.9 3.3 2 1 1 3 3 3 3 BT1 family Actin PF00022.19 KDO17394.1 - 7.6e-10 37.9 0.0 1.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Actin HUN PF08729.10 KDO17394.1 - 0.037 14.0 0.8 0.066 13.2 0.8 1.3 1 0 0 1 1 1 0 HPC2 and ubinuclein domain BT1 PF03092.16 KDO17395.1 - 8.2e-12 44.1 11.6 2.2e-09 36.1 2.0 3.3 3 0 0 3 3 3 3 BT1 family Protocadherin PF08374.11 KDO17397.1 - 0.00048 20.2 0.8 0.00085 19.4 0.8 1.5 1 1 0 1 1 1 1 Protocadherin Trp_oprn_chp PF09534.10 KDO17397.1 - 0.001 18.9 1.1 0.0013 18.6 1.1 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 KDO17397.1 - 0.011 16.6 0.0 0.017 16.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KDO17397.1 - 0.015 14.2 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 KDO17397.1 - 0.092 12.6 0.3 0.092 12.6 0.3 1.5 1 1 1 2 2 2 0 Rifin DUF1180 PF06679.12 KDO17397.1 - 2.8 8.3 7.9 0.57 10.6 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) zf-TRAF PF02176.18 KDO17398.1 - 8.8e-16 58.4 32.3 1.6e-05 25.5 3.9 5.0 2 2 3 5 5 5 5 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KDO17398.1 - 0.055 13.9 29.6 0.094 13.2 4.2 3.8 1 1 1 3 3 3 0 TRAF-like zinc-finger Sina PF03145.16 KDO17398.1 - 4.1 7.3 27.0 1.1 9.1 3.4 4.3 1 1 4 5 5 5 0 Seven in absentia protein family DUF1619 PF07773.11 KDO17399.1 - 3e-30 106.3 0.4 2.2e-28 100.1 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) Cpn60_TCP1 PF00118.24 KDO17401.1 - 8e-80 268.8 3.8 8.9e-80 268.7 3.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcrB PF01884.17 KDO17401.1 - 0.0013 18.3 0.2 1.7 8.1 0.1 2.3 2 0 0 2 2 2 2 PcrB family DUF2150 PF09920.9 KDO17401.1 - 0.38 10.7 2.0 0.68 9.9 0.0 2.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2150) DUF333 PF03891.15 KDO17402.1 - 0.017 15.3 0.1 0.31 11.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF333) DUF4246 PF14033.6 KDO17403.1 - 0.0073 15.5 0.1 0.02 14.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) bZIP_1 PF00170.21 KDO17407.1 - 0.049 13.7 7.4 1.8 8.7 5.7 2.1 2 0 0 2 2 2 0 bZIP transcription factor KdpD PF02702.17 KDO17407.1 - 0.054 13.0 0.4 0.064 12.7 0.4 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain bZIP_2 PF07716.15 KDO17407.1 - 0.09 12.9 0.2 0.09 12.9 0.2 2.6 2 1 0 2 2 2 0 Basic region leucine zipper RIBIOP_C PF04950.12 KDO17407.1 - 0.24 10.8 0.5 0.29 10.5 0.5 1.0 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PET117 PF15786.5 KDO17407.1 - 5.8 7.2 10.2 2 8.7 6.2 2.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Radical_SAM PF04055.21 KDO17408.1 - 0.013 15.9 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Radical SAM superfamily zf-C2H2_10 PF16588.5 KDO17408.1 - 0.41 10.4 2.4 0.7 9.7 2.4 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger CSRNP_N PF16019.5 KDO17409.1 - 4.1e-10 40.0 0.2 7e-10 39.2 0.2 1.4 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus HA PF03457.14 KDO17409.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Helicase associated domain MFS_3 PF05977.13 KDO17409.1 - 0.16 10.3 0.0 0.17 10.2 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector PIG-P PF08510.12 KDO17412.1 - 1.4e-37 128.3 6.2 1.7e-37 128.0 6.2 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KDO17412.1 - 2.7e-05 24.4 6.6 4.5e-05 23.7 6.6 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) FixQ PF05545.11 KDO17412.1 - 0.056 13.4 0.8 0.056 13.4 0.8 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4519 PF15012.6 KDO17412.1 - 4.3 7.6 5.7 0.45 10.7 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Peptidase_S24 PF00717.23 KDO17413.1 - 1.4e-09 37.8 0.0 3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KDO17413.1 - 0.015 15.1 0.0 2.7 7.8 0.0 2.7 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Uma2 PF05685.12 KDO17413.1 - 0.094 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative restriction endonuclease EGF_2 PF07974.13 KDO17414.1 - 4e-06 27.1 16.8 0.0023 18.2 8.2 2.4 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 KDO17414.1 - 0.00047 20.2 13.1 0.14 12.4 6.0 2.5 2 0 0 2 2 2 2 Laminin EGF domain EGF PF00008.27 KDO17414.1 - 0.0021 18.3 8.3 0.3 11.4 0.1 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KDO17414.1 - 0.17 12.6 0.6 0.17 12.6 0.6 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF KH_1 PF00013.29 KDO17414.1 - 0.21 11.4 0.0 23 4.9 0.0 2.3 2 0 0 2 2 2 0 KH domain EGF_Tenascin PF18720.1 KDO17414.1 - 0.25 11.4 13.4 0.31 11.1 0.9 2.6 2 0 0 2 2 2 0 Tenascin EGF domain I-EGF_1 PF18372.1 KDO17414.1 - 5.2 7.2 9.6 16 5.7 3.8 2.6 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KDO17415.1 - 1.3e-09 38.2 43.3 2.7e-05 24.4 3.9 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_Tenascin PF18720.1 KDO17415.1 - 1.7e-05 24.8 35.2 0.2 11.7 7.4 4.5 4 0 0 4 4 4 4 Tenascin EGF domain EGF PF00008.27 KDO17415.1 - 0.0006 20.1 34.2 0.012 15.9 3.1 4.7 4 0 0 4 4 4 2 EGF-like domain Laminin_EGF PF00053.24 KDO17415.1 - 0.0011 19.0 33.9 0.025 14.7 7.4 3.7 2 1 1 3 3 3 2 Laminin EGF domain hEGF PF12661.7 KDO17415.1 - 0.018 15.6 33.6 0.039 14.6 4.2 5.1 4 0 0 4 4 4 0 Human growth factor-like EGF Sep15_SelM PF08806.11 KDO17416.1 - 1.3e-07 31.7 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain TOBE PF03459.17 KDO17416.1 - 0.18 12.1 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 TOBE domain Carn_acyltransf PF00755.20 KDO17420.1 - 1.4e-143 479.6 0.0 1.2e-133 446.9 0.0 2.0 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase p450 PF00067.22 KDO17422.1 - 1.2e-46 159.4 0.0 6.4e-36 124.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DAO PF01266.24 KDO17423.1 - 1.6e-39 136.5 0.0 2e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO17423.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO17423.1 - 0.035 12.8 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Ribosomal_S6e PF01092.19 KDO17423.1 - 0.091 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e RINGv PF12906.7 KDO17423.1 - 0.16 12.2 0.4 0.31 11.2 0.4 1.4 1 0 0 1 1 1 0 RING-variant domain DAO PF01266.24 KDO17424.1 - 5.2e-36 125.0 0.0 5.9e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO17424.1 - 0.0027 16.5 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KDO17424.1 - 0.0055 16.0 0.0 0.0074 15.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S6e PF01092.19 KDO17424.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S6e NadA PF02445.16 KDO17425.1 - 0.0081 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Quinolinate synthetase A protein DAO PF01266.24 KDO17426.1 - 3e-39 135.6 4.5 3.3e-39 135.4 4.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO17426.1 - 9.8e-06 24.9 0.5 1.4e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KDO17426.1 - 0.00013 22.3 0.1 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KDO17426.1 - 0.0016 18.9 1.7 0.0079 16.7 1.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KDO17426.1 - 0.0017 17.6 2.4 0.011 15.0 1.7 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO17426.1 - 0.0054 16.7 0.1 0.024 14.6 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KDO17426.1 - 0.011 16.0 1.0 0.045 14.0 0.5 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KDO17426.1 - 0.021 14.1 0.6 0.066 12.5 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KDO17426.1 - 0.046 13.3 0.1 0.27 10.8 0.3 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KDO17426.1 - 0.14 11.4 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KDO17426.1 - 0.18 12.1 0.3 0.63 10.3 0.2 1.8 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 KDO17426.1 - 0.51 9.4 1.8 0.75 8.8 1.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TPR_12 PF13424.6 KDO17427.1 - 1.6e-11 44.3 14.2 1e-06 28.9 1.3 4.8 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO17427.1 - 8.1e-11 41.2 14.1 0.00092 19.2 0.6 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO17427.1 - 4.2e-08 32.8 0.5 0.12 12.7 0.1 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO17427.1 - 7.2e-08 31.9 6.4 0.0017 18.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO17427.1 - 8.3e-08 31.7 4.6 0.00078 19.2 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO17427.1 - 6.7e-07 29.0 14.0 0.0016 18.2 0.2 6.1 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17427.1 - 1.3e-06 28.7 22.5 0.49 11.3 0.1 6.9 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO17427.1 - 2.1e-06 28.1 12.4 0.0092 16.5 1.2 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 KDO17427.1 - 9.6e-06 25.4 4.7 0.002 17.9 1.3 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 KDO17427.1 - 1.3e-05 25.7 19.0 0.027 15.1 5.4 6.2 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO17427.1 - 1.4e-05 25.4 4.1 0.64 10.8 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat Paf67 PF10255.9 KDO17427.1 - 0.012 14.7 0.0 1.9 7.4 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_17 PF13431.6 KDO17427.1 - 0.039 14.3 5.9 8.1 7.1 1.5 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO17427.1 - 0.039 14.6 12.0 0.13 12.9 1.5 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO17427.1 - 0.062 13.5 4.7 0.86 9.9 0.9 3.8 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Abhydrolase_6 PF12697.7 KDO17428.1 - 2e-08 35.1 2.5 2.6e-08 34.7 2.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO17428.1 - 3.4e-06 26.5 0.1 2.9e-05 23.5 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KDO17428.1 - 5.5e-06 26.0 0.1 3e-05 23.6 0.0 2.0 1 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KDO17428.1 - 5.8e-05 22.8 0.1 0.0003 20.5 0.1 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KDO17428.1 - 0.0012 18.5 0.0 0.61 9.7 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KDO17428.1 - 0.0042 16.8 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KDO17428.1 - 0.072 12.6 0.8 0.86 9.0 0.3 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase SBF PF01758.16 KDO17429.1 - 3.4e-38 131.3 15.1 3.4e-38 131.3 15.1 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 KDO17429.1 - 6.9e-09 35.5 23.4 8.4e-09 35.2 23.4 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) LRR_6 PF13516.6 KDO17431.1 - 1.4e-15 55.9 7.0 0.0011 18.8 0.1 4.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KDO17431.1 - 2e-06 28.0 0.1 0.062 13.7 0.0 3.8 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO17431.1 - 0.0085 15.8 0.3 2.6 7.9 0.4 3.8 2 1 1 3 3 3 2 Leucine rich repeat Aminotran_4 PF01063.19 KDO17432.1 - 1.3e-06 28.4 0.1 2.6e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Amino-transferase class IV GvpK PF05121.12 KDO17432.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein K Abhydrolase_1 PF00561.20 KDO17433.1 - 4.4e-26 92.1 0.0 3.6e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO17433.1 - 2.4e-13 51.2 6.8 2.9e-13 50.9 6.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO17433.1 - 1.6e-11 43.9 2.3 4.8e-11 42.4 2.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KDO17433.1 - 0.0046 16.5 0.3 0.65 9.4 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Thioesterase PF00975.20 KDO17433.1 - 0.0053 16.9 0.3 0.012 15.7 0.3 1.9 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KDO17433.1 - 0.0062 16.3 1.3 0.014 15.2 1.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 KDO17433.1 - 0.059 12.1 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 KDO17434.1 - 3.5e-20 72.7 0.1 3e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO17434.1 - 8.7e-15 54.6 0.1 1.4e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO17434.1 - 9.3e-13 49.3 0.8 1.2e-12 48.9 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KDO17434.1 - 0.001 18.7 0.0 0.91 9.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KDO17434.1 - 0.021 14.3 0.9 0.7 9.3 0.1 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KDO17434.1 - 0.022 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.18 KDO17434.1 - 0.037 13.6 0.0 0.073 12.7 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 KDO17434.1 - 0.038 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 KDO17435.1 - 2.7e-20 73.1 0.1 4e-19 69.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO17435.1 - 4.1e-15 57.0 3.8 5.2e-15 56.6 3.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO17435.1 - 7.6e-14 51.5 0.2 1.1e-13 51.0 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 KDO17435.1 - 0.024 13.3 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Thioesterase PF00975.20 KDO17435.1 - 0.075 13.1 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 KDO17435.1 - 0.12 11.9 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 KDO17435.1 - 0.15 11.7 0.5 0.38 10.4 0.5 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KDO17436.1 - 1.2e-24 87.3 1.1 9.4e-20 71.3 0.4 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO17436.1 - 2.5e-12 47.9 15.0 3.4e-12 47.5 15.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO17436.1 - 5.5e-12 45.5 2.6 1.2e-11 44.4 2.6 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KDO17436.1 - 0.0017 17.9 0.3 0.0017 17.9 0.3 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KDO17436.1 - 0.0022 17.7 0.4 0.014 15.1 0.3 2.3 1 1 0 2 2 2 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 KDO17436.1 - 0.01 15.6 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KDO17436.1 - 0.1 12.7 0.9 0.25 11.4 0.9 1.7 1 1 1 2 2 2 0 Thioesterase domain Uma2 PF05685.12 KDO17437.1 - 0.073 12.6 0.0 0.076 12.5 0.0 1.0 1 0 0 1 1 1 0 Putative restriction endonuclease UBM PF14377.6 KDO17439.1 - 0.034 13.6 0.1 0.13 11.7 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin binding region DUF3499 PF12005.8 KDO17439.1 - 0.16 12.6 0.0 0.64 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) CENP-B_dimeris PF09026.10 KDO17440.1 - 0.045 14.1 0.8 0.046 14.1 0.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KDO17440.1 - 0.053 13.2 2.6 0.061 13.0 2.6 1.0 1 0 0 1 1 1 0 FAM176 family Pox_RNA_Pol_19 PF05320.12 KDO17440.1 - 0.2 11.6 1.2 0.21 11.6 1.2 1.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Stk19 PF10494.9 KDO17441.1 - 2.4e-22 79.8 0.0 3.6e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF1640 PF07798.11 KDO17443.1 - 2.2e-08 34.3 4.4 7e-07 29.5 4.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Peroxidase_2 PF01328.17 KDO17443.1 - 0.11 13.0 0.2 0.14 12.7 0.2 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 Peptidase_S28 PF05577.12 KDO17446.1 - 7.8e-108 361.0 0.1 9.1e-108 360.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 KDO17446.1 - 8.3e-05 22.3 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 KDO17446.1 - 0.00024 19.9 0.1 0.00039 19.2 0.1 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S28 PF05577.12 KDO17448.1 - 7.2e-36 123.9 0.1 8.7e-36 123.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Deltaretro_Tax PF05599.11 KDO17448.1 - 0.12 12.9 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Dynein_C PF18199.1 KDO17449.1 - 5e-54 183.6 0.0 5.6e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain zf-C3HC4_4 PF15227.6 KDO17450.1 - 4.6e-06 26.7 11.8 4.6e-06 26.7 11.8 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO17450.1 - 7.6e-05 22.7 8.7 7.6e-05 22.7 8.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO17450.1 - 7.9e-05 22.4 11.4 0.00026 20.8 11.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO17450.1 - 0.00018 21.3 11.0 0.00018 21.3 11.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO17450.1 - 0.00042 20.6 14.2 0.00042 20.6 14.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KDO17450.1 - 0.057 13.4 14.4 0.17 11.9 14.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO17450.1 - 0.18 11.7 12.0 0.54 10.2 12.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DNA_pol_phi PF04931.13 KDO17450.1 - 0.33 9.0 6.6 0.43 8.6 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_10 PF16685.5 KDO17450.1 - 0.84 9.8 11.6 2.2 8.5 11.3 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KDO17450.1 - 2 8.4 23.1 0.082 12.8 15.8 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF3245 PF11595.8 KDO17450.1 - 4 7.9 5.7 13 6.2 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) Complex1_LYR PF05347.15 KDO17451.1 - 7.2e-14 51.6 0.9 9.9e-14 51.1 0.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO17451.1 - 1.1e-05 26.0 0.7 1.4e-05 25.8 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like zf-ribbon_3 PF13248.6 KDO17451.1 - 3.3e-05 23.1 3.1 3.3e-05 23.1 3.1 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Complex1_LYR_1 PF13232.6 KDO17451.1 - 0.0054 17.3 0.3 0.0091 16.6 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like DZR PF12773.7 KDO17451.1 - 0.009 16.0 10.0 0.014 15.4 10.0 1.6 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KDO17451.1 - 0.015 16.1 2.5 0.015 16.1 2.5 1.5 1 1 0 1 1 1 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KDO17451.1 - 0.034 13.9 5.2 0.13 12.0 5.2 2.0 1 1 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KDO17451.1 - 0.037 14.2 1.5 0.1 12.8 1.5 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PLATZ PF04640.14 KDO17451.1 - 0.053 14.2 2.0 0.06 14.0 1.8 1.5 1 1 0 1 1 1 0 PLATZ transcription factor Cwf_Cwc_15 PF04889.12 KDO17451.1 - 0.068 12.9 0.2 0.078 12.7 0.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HypA PF01155.19 KDO17451.1 - 0.16 12.0 1.8 0.13 12.3 1.0 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cript PF10235.9 KDO17451.1 - 0.26 11.9 4.3 0.16 12.5 2.5 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-NADH-PPase PF09297.11 KDO17451.1 - 0.75 9.5 9.3 1.9 8.2 0.3 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain TF_Zn_Ribbon PF08271.12 KDO17451.1 - 1.2 8.7 3.8 3.9 7.1 3.8 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding DUF35_N PF12172.8 KDO17451.1 - 2.4 8.1 7.0 0.65 9.9 3.6 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C3HC4_4 PF15227.6 KDO17452.1 - 6.1e-08 32.7 12.0 2.5e-07 30.7 12.1 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO17452.1 - 0.00017 21.5 8.5 0.00017 21.5 8.5 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO17452.1 - 0.0021 17.8 18.4 0.0041 17.0 18.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO17452.1 - 0.0066 16.3 16.2 0.02 14.7 16.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO17452.1 - 0.0077 16.1 16.0 0.0077 16.1 16.0 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO17452.1 - 0.038 14.0 14.7 0.098 12.6 14.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO17452.1 - 2.3 8.1 19.3 4.6 7.2 19.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4196 PF13846.6 KDO17452.1 - 2.7 8.2 24.6 0.066 13.4 17.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) zf-TRM13_CCCH PF11722.8 KDO17454.1 - 0.35 10.7 3.0 0.66 9.8 1.7 2.2 2 1 1 3 3 3 0 CCCH zinc finger in TRM13 protein Retrotrans_gag PF03732.17 KDO17455.1 - 0.00083 19.6 0.3 0.00083 19.6 0.3 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KDO17455.1 - 0.01 15.9 4.3 0.016 15.2 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle TBCC_N PF16752.5 KDO17455.1 - 0.015 15.7 2.0 0.097 13.1 0.1 2.3 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain zf-CCHC_3 PF13917.6 KDO17455.1 - 0.017 15.1 1.1 0.033 14.2 0.4 1.7 2 0 0 2 2 2 0 Zinc knuckle ABATE PF07336.11 KDO17455.1 - 0.11 13.1 11.0 0.045 14.4 1.7 3.2 1 1 2 3 3 3 0 Putative stress-induced transcription regulator Hist_deacetyl PF00850.19 KDO17456.1 - 3e-49 168.2 0.5 3.3e-49 168.0 0.5 1.0 1 0 0 1 1 1 1 Histone deacetylase domain PEP_mutase PF13714.6 KDO17458.1 - 3.6e-53 180.5 0.1 4.1e-53 180.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KDO17458.1 - 2.9e-13 49.2 0.3 3.7e-13 48.8 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KDO17458.1 - 0.0006 19.3 0.0 0.0014 18.0 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase DndB PF14072.6 KDO17459.1 - 0.00069 18.9 0.0 0.00075 18.8 0.0 1.1 1 0 0 1 1 1 1 DNA-sulfur modification-associated ParBc PF02195.18 KDO17459.1 - 0.00072 19.8 0.1 0.0022 18.3 0.1 1.8 1 1 0 1 1 1 1 ParB-like nuclease domain DUF1015 PF06245.11 KDO17459.1 - 0.0028 16.6 0.1 0.0028 16.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) ParBc_2 PF08857.11 KDO17459.1 - 0.0046 17.1 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative ParB-like nuclease RES PF08808.11 KDO17459.1 - 0.023 14.5 0.9 0.03 14.2 0.9 1.1 1 0 0 1 1 1 0 RES domain DUF834 PF05754.14 KDO17459.1 - 0.22 11.6 0.9 20 5.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF834) RFC1 PF08519.12 KDO17460.1 - 0.19 11.9 0.5 0.34 11.1 0.5 1.4 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain PBP1_TM PF14812.6 KDO17460.1 - 4.9 7.6 16.2 1.8 9.0 11.6 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYVE PF01363.21 KDO17461.1 - 2.3e-10 40.5 12.4 5.5e-10 39.2 12.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO17461.1 - 0.0085 16.3 7.7 0.021 15.0 7.7 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger TraG-D_C PF12696.7 KDO17461.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG GlcNAc-1_reg PF18440.1 KDO17462.1 - 0.021 15.1 0.3 0.033 14.4 0.3 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Syntaxin_2 PF14523.6 KDO17464.1 - 2.6e-09 37.4 5.6 5.7e-09 36.3 3.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein FAA_hydrolase_N PF09298.11 KDO17464.1 - 0.011 16.0 1.2 0.011 16.0 1.2 2.0 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal PhageMin_Tail PF10145.9 KDO17464.1 - 0.016 15.0 3.2 0.034 14.0 2.8 1.6 1 1 0 1 1 1 0 Phage-related minor tail protein YusW PF14039.6 KDO17464.1 - 0.094 13.2 2.8 0.099 13.2 0.3 2.2 2 1 1 3 3 3 0 YusW-like protein Syntaxin PF00804.25 KDO17464.1 - 0.13 11.9 8.8 3.1 7.4 8.8 2.3 1 1 0 1 1 1 0 Syntaxin ING PF12998.7 KDO17464.1 - 0.15 12.6 1.7 0.56 10.8 0.3 2.0 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Sec8_exocyst PF04048.14 KDO17464.1 - 0.17 11.8 4.2 0.38 10.6 2.4 2.3 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF5344 PF17279.2 KDO17464.1 - 0.17 12.5 4.4 7.6 7.2 0.9 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Mod_r PF07200.13 KDO17464.1 - 0.65 10.1 6.9 12 6.0 6.6 2.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.10 KDO17464.1 - 0.94 9.7 7.6 4.5 7.5 1.5 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SSXT PF05030.12 KDO17465.1 - 0.046 13.4 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) DUF4562 PF15123.6 KDO17465.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) PH PF00169.29 KDO17467.1 - 2.4e-06 28.0 0.0 3.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 PH domain Axin_b-cat_bind PF08833.10 KDO17467.1 - 0.024 14.7 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Axin beta-catenin binding domain 4HBT PF03061.22 KDO17469.1 - 3.8e-21 75.2 0.3 1e-13 51.4 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 KDO17469.1 - 0.0001 21.8 0.3 0.15 11.6 0.5 2.4 2 0 0 2 2 2 2 MaoC like domain Adeno_E3_15_3 PF03307.14 KDO17469.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region zf_CCCH_4 PF18345.1 KDO17470.1 - 3.2e-19 68.3 40.0 2.9e-07 30.3 4.6 5.4 5 0 0 5 5 5 3 Zinc finger domain zf-CCCH PF00642.24 KDO17470.1 - 3.9e-18 64.9 30.5 1.5e-10 40.7 2.6 4.3 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO17470.1 - 7e-11 41.7 32.4 2.1e-06 27.4 0.6 4.7 5 0 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 KDO17470.1 - 1e-10 42.3 19.3 2.5e-05 24.9 0.9 3.3 1 1 0 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 KDO17470.1 - 7.6e-10 38.9 33.1 0.0002 21.7 3.2 4.6 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KDO17470.1 - 0.00021 21.5 17.1 0.0062 16.7 3.2 3.3 1 1 1 3 3 3 2 Zinc-finger containing family bZIP_1 PF00170.21 KDO17471.1 - 1.1 9.4 3.8 4.9 7.3 1.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor CAF1-p150_C2 PF15539.6 KDO17472.1 - 0.2 11.1 2.9 3 7.2 0.7 2.0 1 1 1 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term AA_permease_2 PF13520.6 KDO17473.1 - 2e-12 46.7 37.7 1.6e-11 43.7 24.1 2.4 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KDO17473.1 - 5.2e-05 22.0 23.9 5.2e-05 22.0 23.9 2.4 1 1 0 2 2 2 2 Amino acid permease Pkinase_Tyr PF07714.17 KDO17475.1 - 3.7e-37 128.0 0.0 2e-36 125.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17475.1 - 2.1e-36 125.6 0.0 2.7e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO17475.1 - 0.0023 16.8 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO17475.1 - 0.0089 16.0 0.3 0.016 15.1 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO17475.1 - 0.011 15.1 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Viral_DNA_bp PF00747.17 KDO17476.1 - 0.14 9.3 0.0 0.18 9.0 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein Phage_terminase PF10668.9 KDO17476.1 - 0.19 11.8 0.3 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Phage terminase small subunit MA3 PF02847.17 KDO17478.1 - 1.1e-25 89.8 0.2 1.7e-25 89.2 0.2 1.3 1 0 0 1 1 1 1 MA3 domain CCDC24 PF15669.5 KDO17478.1 - 0.12 12.2 1.0 0.18 11.7 1.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family FAM176 PF14851.6 KDO17478.1 - 6.3 6.5 6.9 1.8 8.2 0.6 2.5 2 1 0 2 2 2 0 FAM176 family CDC50 PF03381.15 KDO17479.1 - 1.7e-85 286.9 0.0 2.7e-85 286.3 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family YpzI PF14140.6 KDO17479.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 YpzI-like protein CDC50 PF03381.15 KDO17480.1 - 1.1e-78 264.6 0.0 1.5e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PP2C PF00481.21 KDO17481.1 - 9.8e-32 110.6 0.0 3.2e-31 108.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C WW PF00397.26 KDO17483.1 - 0.0012 18.8 0.8 0.1 12.7 0.1 2.6 2 0 0 2 2 2 2 WW domain DUF2508 PF10704.9 KDO17483.1 - 0.29 11.3 2.6 6.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Ank_2 PF12796.7 KDO17484.1 - 2e-38 130.9 5.5 6.7e-13 49.0 0.0 6.1 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17484.1 - 4.2e-31 103.5 10.2 7.8e-05 22.8 0.1 9.1 9 1 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 KDO17484.1 - 1.6e-30 105.1 5.9 3e-05 24.5 0.1 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17484.1 - 3.7e-24 84.5 9.1 3.4e-08 33.6 0.0 7.0 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO17484.1 - 8.7e-20 70.2 15.8 0.00089 19.6 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat DUF3015 PF11220.8 KDO17484.1 - 0.072 12.9 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) Med8 PF10232.9 KDO17485.1 - 8.3e-11 41.9 9.2 2.2e-10 40.6 9.2 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Peptidase_M48 PF01435.18 KDO17486.1 - 3.7e-25 88.8 0.0 1.3e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M1 PF01433.20 KDO17486.1 - 0.068 12.7 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M1 domain Imm75 PF15660.6 KDO17486.1 - 0.1 12.9 0.5 23 5.3 0.0 2.8 3 0 0 3 3 3 0 Putative Immunity protein 75 RNAse_A_bac PF18431.1 KDO17487.1 - 0.0057 17.6 0.0 0.0097 16.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial CdiA-CT RNAse A domain NOA36 PF06524.12 KDO17491.1 - 0.082 12.2 3.3 0.11 11.8 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KDO17491.1 - 0.27 10.9 6.5 0.37 10.5 6.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M1 PF01433.20 KDO17494.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain TsaE PF02367.17 KDO17495.1 - 7.4e-18 64.8 0.1 8.4e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tfb5 PF06331.12 KDO17496.1 - 1.3e-25 89.1 0.0 1.5e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 2OG-FeII_Oxy PF03171.20 KDO17497.1 - 0.00019 21.9 0.0 0.00027 21.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KDO17497.1 - 0.00052 20.9 0.0 0.00076 20.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KDO17497.1 - 0.0012 19.1 0.3 0.016 15.4 0.2 2.0 1 1 1 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.6 KDO17499.1 - 4.6e-43 147.6 36.8 1.4e-41 142.7 36.8 2.1 1 1 0 1 1 1 1 Amino acid permease PKD_channel PF08016.12 KDO17502.1 - 8.9e-17 60.9 17.2 4.8e-11 42.0 11.7 2.5 1 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 KDO17502.1 - 3.8e-05 23.0 16.6 0.00013 21.3 16.6 1.9 1 1 0 1 1 1 1 Ion transport protein HTH_23 PF13384.6 KDO17502.1 - 0.026 14.3 0.2 0.065 13.1 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KDO17502.1 - 0.15 12.2 0.2 0.33 11.1 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Lipase_3 PF01764.25 KDO17503.1 - 3.9e-28 98.1 0.0 6.1e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KDO17503.1 - 0.0007 19.2 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KDO17503.1 - 0.0012 19.5 0.1 0.0015 19.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO17503.1 - 0.0086 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.7 KDO17504.1 - 3.9e-19 69.0 7.8 6e-07 30.0 0.3 6.4 4 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17504.1 - 7.3e-11 42.4 20.7 0.71 10.5 0.2 9.5 5 3 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17504.1 - 1.3e-09 37.5 7.1 16 6.5 0.0 10.4 11 0 0 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 KDO17504.1 - 1.2e-05 25.5 12.9 5.1 7.5 0.0 8.6 8 1 2 10 10 10 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17506.1 - 9.6e-29 99.8 1.1 1.4e-13 51.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO17506.1 - 2.2e-14 53.2 4.8 0.0018 18.7 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO17506.1 - 9.9e-14 51.5 1.2 1.9e-06 28.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17506.1 - 4.3e-13 49.2 1.2 5.2e-10 39.4 0.2 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17506.1 - 1.1e-11 43.9 0.2 0.034 14.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat AAA PF00004.29 KDO17506.1 - 2.3e-08 34.5 0.0 4.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO17506.1 - 0.00035 20.9 0.1 0.055 13.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KDO17506.1 - 0.0013 19.1 0.5 0.0043 17.5 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain NACHT PF05729.12 KDO17506.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.26 KDO17506.1 - 0.0029 17.3 0.1 0.065 12.9 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 KDO17506.1 - 0.0079 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO17506.1 - 0.015 15.4 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KDO17506.1 - 0.02 15.0 0.0 0.072 13.2 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 KDO17506.1 - 0.025 14.0 0.0 1.6 8.1 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein ResIII PF04851.15 KDO17506.1 - 0.027 14.5 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KDO17506.1 - 0.031 14.0 0.2 0.091 12.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KDO17506.1 - 0.034 13.5 0.0 0.67 9.3 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KDO17506.1 - 0.039 13.7 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CoaE PF01121.20 KDO17506.1 - 0.066 12.9 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_7 PF12775.7 KDO17506.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KDO17506.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO17506.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO17506.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 KDO17506.1 - 0.2 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Retrotrans_gag PF03732.17 KDO17507.1 - 4.7e-12 46.0 0.1 1.1e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 KDO17507.1 - 0.0038 17.8 0.1 0.011 16.3 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KDO17507.1 - 0.024 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KDO17507.1 - 0.038 14.5 1.7 0.11 13.1 0.1 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease MADF_DNA_bdg PF10545.9 KDO17507.1 - 0.057 13.7 0.2 0.21 11.9 0.2 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3886 PF13025.6 KDO17507.1 - 0.51 10.6 6.4 5.9 7.2 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) PEP-utilisers_N PF05524.13 KDO17507.1 - 1.7 8.8 14.3 2.7 8.2 12.7 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Dabb PF07876.12 KDO17510.1 - 1.2e-19 70.7 0.0 1.4e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TMEM169 PF15052.6 KDO17511.1 - 0.056 13.6 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 TMEM169 protein family Tad PF13400.6 KDO17511.1 - 5.2 7.5 6.6 6.6 7.1 6.6 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Sugar_tr PF00083.24 KDO17512.1 - 3e-26 92.3 19.7 2.9e-14 52.8 12.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO17512.1 - 2e-16 59.9 9.9 4.2e-08 32.5 0.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 KDO17512.1 - 0.049 14.0 4.0 0.16 12.3 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) FTR1 PF03239.14 KDO17512.1 - 0.056 12.6 0.3 0.056 12.6 0.3 1.6 2 0 0 2 2 2 0 Iron permease FTR1 family Trep_Strep PF09605.10 KDO17512.1 - 0.4 10.6 0.0 0.4 10.6 0.0 3.2 2 1 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) HIG_1_N PF04588.13 KDO17512.1 - 0.76 10.1 9.3 1.5 9.1 6.1 2.7 2 1 0 2 2 2 0 Hypoxia induced protein conserved region Ras PF00071.22 KDO17513.1 - 6.6e-54 181.9 0.0 7.6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO17513.1 - 4.6e-21 75.2 0.0 6.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO17513.1 - 2.3e-09 37.0 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO17513.1 - 0.00046 19.8 0.0 0.00092 18.8 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Cation_ATPase_N PF00690.26 KDO17514.1 - 1.1e-11 44.2 0.0 1.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PIF1 PF05970.14 KDO17516.1 - 0.0042 16.3 0.0 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase PV-1 PF06637.11 KDO17516.1 - 0.5 9.1 7.2 0.79 8.5 7.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3752 PF12572.8 KDO17516.1 - 0.8 10.2 10.9 1.5 9.3 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Cellulase-like PF12876.7 KDO17517.1 - 0.14 11.4 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-binding cellulase-like PDEase_I PF00233.19 KDO17519.1 - 3.3e-64 216.9 0.0 5.6e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KDO17519.1 - 1.9e-19 70.6 0.6 9.1e-14 52.2 0.1 3.5 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KDO17519.1 - 8.9e-09 35.8 0.0 0.0019 18.5 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KDO17519.1 - 0.011 16.1 0.0 0.1 12.9 0.0 2.7 2 1 0 2 2 2 0 GAF domain EF-hand_6 PF13405.6 KDO17522.1 - 2.2e-11 42.7 1.0 2.2e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KDO17522.1 - 2.8e-11 43.7 0.1 3.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO17522.1 - 5.2e-10 38.1 2.4 5.3e-05 22.5 0.2 2.8 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 KDO17522.1 - 8e-08 31.4 1.0 0.00075 18.9 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO17522.1 - 9.1e-06 25.4 0.1 0.071 13.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 KDO17522.1 - 0.02 14.9 0.0 0.68 9.8 0.0 2.0 1 1 1 2 2 2 0 Caleosin related protein zf-CCHC_5 PF14787.6 KDO17522.1 - 0.09 12.5 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Methyltransf_16 PF10294.9 KDO17523.1 - 7.7e-15 55.1 0.0 1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KDO17523.1 - 0.032 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 KDO17524.1 - 1.3e-27 97.0 0.0 1.9e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Beta_helix PF13229.6 KDO17524.1 - 2.6e-20 72.9 4.2 2.9e-09 37.0 0.0 2.4 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KDO17524.1 - 1.7e-11 43.8 0.3 9.2e-09 34.9 0.4 2.0 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) HCV_NS4a PF01006.20 KDO17524.1 - 0.14 11.9 9.7 1.1 9.1 0.2 3.9 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a Peptidase_S8 PF00082.22 KDO17526.1 - 5.6e-37 127.6 2.9 1.1e-36 126.6 2.9 1.6 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 KDO17526.1 - 3.9e-19 69.1 10.8 2.9e-14 53.4 0.9 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO17526.1 - 1.7e-06 28.6 7.2 0.025 15.3 0.0 3.5 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Actino_peptide PF14408.6 KDO17526.1 - 0.079 13.1 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes CDtoxinA PF03498.14 KDO17526.1 - 0.099 12.2 0.4 0.29 10.7 0.1 1.9 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Peptidase_C2 PF00648.21 KDO17527.1 - 1.1e-42 146.1 0.0 3.2e-42 144.6 0.0 1.7 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 KDO17527.1 - 0.00016 21.7 1.2 0.00016 21.7 1.2 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain CHAD PF05235.14 KDO17527.1 - 0.017 15.1 2.8 0.026 14.5 2.8 1.3 1 0 0 1 1 1 0 CHAD domain Prefoldin_2 PF01920.20 KDO17528.1 - 2.5e-18 65.9 0.8 2.8e-18 65.8 0.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 KDO17528.1 - 0.0048 17.0 0.5 0.0091 16.1 0.5 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad3 DivIVA PF05103.13 KDO17528.1 - 0.02 15.0 1.5 0.084 13.0 0.6 2.0 2 0 0 2 2 2 0 DivIVA protein DUF1488 PF07369.11 KDO17528.1 - 0.027 14.5 0.2 0.068 13.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1488) DUF2630 PF10944.8 KDO17528.1 - 0.048 14.1 1.6 1.8 9.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) TraC_F_IV PF11130.8 KDO17528.1 - 0.077 12.6 1.0 0.17 11.5 1.0 1.5 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer zf-Tim10_DDP PF02953.15 KDO17529.1 - 2.6e-18 65.4 6.4 3.3e-18 65.1 6.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.20 KDO17529.1 - 0.0064 16.6 1.3 0.0071 16.4 1.3 1.1 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region Herpes_BLRF2 PF05812.12 KDO17529.1 - 0.02 15.0 0.3 0.021 14.9 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein CARD_2 PF16739.5 KDO17529.1 - 0.022 14.7 1.2 0.027 14.4 1.1 1.3 1 1 0 1 1 1 0 Caspase recruitment domain Vicilin_N PF04702.12 KDO17529.1 - 0.25 11.1 10.1 0.32 10.8 10.1 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Ribosomal_S21e PF01249.18 KDO17530.1 - 3.8e-36 123.0 0.0 4.5e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e PAN_1 PF00024.26 KDO17531.1 - 1.4e-11 44.2 10.9 0.0098 15.8 0.3 5.4 3 2 2 5 5 5 4 PAN domain PIG-L PF02585.17 KDO17531.1 - 6.6e-06 26.8 0.1 3.1e-05 24.6 0.1 2.2 2 1 0 2 2 2 1 GlcNAc-PI de-N-acetylase PX PF00787.24 KDO17531.1 - 0.002 18.1 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 PX domain PAN_4 PF14295.6 KDO17531.1 - 0.012 15.5 11.5 0.44 10.5 0.3 4.6 4 0 0 4 4 4 0 PAN domain PAN_2 PF08276.11 KDO17531.1 - 0.74 10.0 3.6 7.7 6.7 0.6 2.9 2 0 0 2 2 2 0 PAN-like domain TPR_2 PF07719.17 KDO17532.1 - 1.2e-18 65.6 6.1 0.0003 20.7 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KDO17532.1 - 7e-17 61.3 1.5 5.2e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO17532.1 - 1.1e-15 57.1 2.8 2.9e-09 36.4 0.0 5.4 6 1 0 6 6 6 2 TPR repeat TPR_1 PF00515.28 KDO17532.1 - 5.7e-14 51.2 9.4 0.0064 16.3 0.0 7.3 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO17532.1 - 1.9e-12 46.3 1.0 0.016 15.4 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17532.1 - 3.5e-11 43.0 0.4 0.74 10.8 0.0 6.3 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO17532.1 - 5.6e-08 32.3 1.7 0.27 11.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO17532.1 - 1.7e-07 31.4 5.9 0.58 10.5 0.0 5.5 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO17532.1 - 0.00013 22.6 2.1 0.76 10.5 0.0 4.1 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KDO17532.1 - 0.00094 18.5 0.1 2 7.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO17532.1 - 0.0017 18.6 10.0 0.92 9.8 0.2 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KDO17532.1 - 0.0027 18.2 3.0 7 7.2 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO17532.1 - 0.046 14.1 10.9 3.8 8.1 0.0 5.1 5 2 1 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 KDO17532.1 - 0.36 10.9 1.5 18 5.5 0.0 3.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Disintegrin PF00200.23 KDO17533.1 - 4.1e-24 85.2 81.1 1.8e-05 25.4 16.0 7.9 5 3 2 7 7 7 7 Disintegrin CAF1 PF04857.20 KDO17535.1 - 1.1e-21 77.4 4.4 2.2e-12 46.8 0.0 2.8 2 1 0 2 2 2 2 CAF1 family ribonuclease p450 PF00067.22 KDO17537.1 - 3.3e-09 36.0 0.0 4.2e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.17 KDO17538.1 - 5.9e-05 22.5 0.0 6.3e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17538.1 - 0.002 17.6 0.0 0.002 17.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KDO17539.1 - 4.8e-06 26.1 0.0 0.00091 18.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KDO17539.1 - 0.0057 16.0 0.1 0.0067 15.8 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KDO17539.1 - 0.019 14.2 0.0 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase MTHFR PF02219.17 KDO17540.1 - 1.5e-19 70.4 0.0 1.7e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4157 PF13699.6 KDO17541.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Stap_Strp_tox_C PF02876.17 KDO17543.1 - 0.07 13.4 0.3 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain V-SNARE PF05008.15 KDO17546.1 - 1.8e-14 53.9 3.7 1.8e-14 53.9 3.7 1.9 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KDO17546.1 - 2e-07 31.2 2.8 2e-07 31.2 2.8 2.1 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KDO17546.1 - 3e-07 30.2 7.2 4.3e-06 26.5 0.2 3.5 1 1 3 4 4 4 1 Sec20 Tropomyosin PF00261.20 KDO17546.1 - 0.00041 19.8 10.4 0.013 14.9 1.1 2.1 2 0 0 2 2 2 2 Tropomyosin DUF1664 PF07889.12 KDO17546.1 - 0.0015 18.6 8.7 0.12 12.4 0.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KDO17546.1 - 0.0058 16.6 11.4 0.23 11.5 1.0 2.9 1 1 0 2 2 2 2 Laminin Domain II DUF4407 PF14362.6 KDO17546.1 - 0.0093 15.3 5.0 0.012 15.0 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PRT_C PF08372.10 KDO17546.1 - 0.019 14.8 0.4 1.4 8.6 0.0 2.4 2 1 1 3 3 3 0 Plant phosphoribosyltransferase C-terminal DUF1640 PF07798.11 KDO17546.1 - 0.023 14.7 8.1 0.035 14.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Synaptobrevin PF00957.21 KDO17546.1 - 0.036 13.9 0.2 0.036 13.9 0.2 2.0 2 0 0 2 2 2 0 Synaptobrevin TOM20_plant PF06552.12 KDO17546.1 - 0.047 13.4 0.9 0.48 10.1 0.1 2.1 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2408 PF10303.9 KDO17546.1 - 0.058 14.0 5.1 0.14 12.8 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PilJ PF13675.6 KDO17546.1 - 0.06 13.4 4.1 0.11 12.5 3.0 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HrpB7 PF09486.10 KDO17546.1 - 0.07 13.5 11.9 0.26 11.6 3.4 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) RGS12_us1 PF16613.5 KDO17546.1 - 0.074 13.4 1.0 0.2 12.0 1.0 1.7 1 0 0 1 1 1 0 Unstructured region of RGS12 DUF4208 PF13907.6 KDO17546.1 - 0.075 13.5 1.4 0.15 12.5 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) AAA_13 PF13166.6 KDO17546.1 - 0.1 11.2 8.6 0.14 10.8 8.6 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KDO17546.1 - 0.14 11.0 10.5 0.18 10.6 10.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KDO17546.1 - 0.18 12.3 3.4 2.8 8.5 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KDO17546.1 - 0.22 11.0 10.6 0.34 10.4 10.6 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit ZnuA PF01297.17 KDO17546.1 - 0.35 10.3 2.4 0.61 9.5 2.0 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Nsp1_C PF05064.13 KDO17546.1 - 0.37 10.6 5.8 6.8 6.5 0.1 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region Fib_alpha PF08702.10 KDO17546.1 - 0.38 10.9 8.4 0.79 9.9 6.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 KDO17546.1 - 0.4 10.9 8.1 9.6 6.5 0.3 3.2 2 1 1 3 3 3 0 Haemolysin XhlA EzrA PF06160.12 KDO17546.1 - 0.98 7.5 11.3 2.6 6.1 11.3 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA PMC2NT PF08066.12 KDO17546.1 - 1.1 10.0 4.3 7.8 7.3 0.2 2.5 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Nup54 PF13874.6 KDO17546.1 - 1.7 8.8 7.7 1.3 9.1 6.0 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.11 KDO17546.1 - 2.7 8.6 8.0 24 5.6 8.0 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 KDO17546.1 - 2.8 8.3 11.7 8.6 6.7 0.6 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 KDO17546.1 - 3 8.3 11.2 5.1 7.6 4.0 3.0 1 1 2 3 3 3 0 Snapin/Pallidin Occludin_ELL PF07303.13 KDO17546.1 - 3.7 8.3 7.7 31 5.4 0.2 3.0 2 1 0 2 2 2 0 Occludin homology domain TEX13 PF15186.6 KDO17546.1 - 4.2 7.0 8.9 2.2 8.0 1.9 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF16 PF01519.16 KDO17546.1 - 4.5 7.8 10.9 8.7 6.9 6.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2205 PF10224.9 KDO17546.1 - 6 6.9 9.4 0.56 10.2 1.9 2.8 1 1 2 3 3 3 0 Short coiled-coil protein DUF2203 PF09969.9 KDO17546.1 - 6.9 7.4 9.8 20 5.9 0.7 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CcmD PF04995.14 KDO17547.1 - 0.47 10.6 2.7 1.5 9.0 2.7 1.9 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Ssu72 PF04722.13 KDO17548.1 - 2.3e-44 151.2 0.0 2.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein FlaC_arch PF05377.11 KDO17549.1 - 0.0058 17.0 2.3 0.012 16.0 0.1 2.5 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 KDO17549.1 - 0.0083 16.4 1.0 0.0083 16.4 1.0 2.6 2 1 1 3 3 3 1 Csm1 N-terminal domain PBC PF03792.13 KDO17549.1 - 0.017 14.9 6.3 0.025 14.4 6.3 1.3 1 0 0 1 1 1 0 PBC domain GAS PF13851.6 KDO17549.1 - 0.021 14.2 8.2 0.032 13.6 8.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 KDO17549.1 - 0.042 13.2 9.2 0.027 13.8 2.0 2.1 1 1 1 2 2 2 0 Tropomyosin DivIC PF04977.15 KDO17549.1 - 0.59 9.9 4.2 0.27 11.0 0.3 2.3 2 1 0 2 2 2 0 Septum formation initiator Cep57_CLD_2 PF14197.6 KDO17549.1 - 0.68 10.1 7.1 5 7.3 0.2 2.6 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 KDO17549.1 - 1.1 9.3 11.3 1.8 8.6 2.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KDO17549.1 - 2.1 8.4 5.2 1.9 8.5 0.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5309 PF17236.2 KDO17550.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5309) Pkinase_Tyr PF07714.17 KDO17552.1 - 5.5e-10 39.0 0.0 6.2e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17552.1 - 2.9e-09 36.7 0.0 3.4e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain SicP-binding PF09119.10 KDO17552.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 SicP binding Clathrin PF00637.20 KDO17556.1 - 0.0011 18.8 3.1 0.065 13.1 0.5 3.0 1 1 2 3 3 3 2 Region in Clathrin and VPS TBPIP_N PF15517.6 KDO17556.1 - 0.02 14.9 0.2 5 7.2 0.1 3.1 3 0 0 3 3 3 0 TBP-interacting protein N-terminus Nic96 PF04097.14 KDO17556.1 - 0.036 12.5 0.5 0.24 9.8 0.1 2.0 2 0 0 2 2 2 0 Nup93/Nic96 HHH_3 PF12836.7 KDO17557.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 KDO17557.1 - 0.052 12.9 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K TPR_8 PF13181.6 KDO17558.1 - 0.036 14.3 0.1 0.085 13.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO17558.1 - 0.11 12.6 1.1 0.74 10.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PC_rep PF01851.22 KDO17559.1 - 1.9e-06 28.0 7.4 0.44 11.1 0.0 5.3 5 0 0 5 5 5 3 Proteasome/cyclosome repeat APC1_C PF18122.1 KDO17559.1 - 0.14 12.1 2.9 0.098 12.6 0.8 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain AAA_22 PF13401.6 KDO17560.1 - 2.4e-05 24.6 0.1 0.0002 21.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain FHA PF00498.26 KDO17560.1 - 3.2e-05 24.2 0.0 9.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 FHA domain AAA_16 PF13191.6 KDO17560.1 - 7.5e-05 23.2 0.0 0.00024 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain CHAT PF12770.7 KDO17560.1 - 0.0018 17.8 0.0 0.0087 15.5 0.0 2.0 1 1 0 1 1 1 1 CHAT domain AAA_30 PF13604.6 KDO17560.1 - 0.0081 15.9 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KDO17560.1 - 0.037 13.9 0.1 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KDO17560.1 - 0.059 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KDO17560.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF667 PF05018.13 KDO17562.1 - 1e-30 106.9 0.0 2.9e-30 105.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF667) PAT1 PF09770.9 KDO17563.1 - 0.0002 19.8 31.7 0.0002 19.8 31.7 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 KDO17563.1 - 0.0011 17.0 13.8 0.0012 16.9 13.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GREB1 PF15782.5 KDO17563.1 - 0.3 8.2 20.9 0.31 8.1 20.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 KDO17563.1 - 0.39 9.7 18.3 0.51 9.3 18.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CCSAP PF15748.5 KDO17563.1 - 0.48 10.6 27.6 0.73 10.0 27.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AAA_23 PF13476.6 KDO17563.1 - 0.51 10.8 24.5 0.85 10.1 24.5 1.5 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 KDO17563.1 - 0.82 8.4 22.1 1.2 7.8 22.1 1.4 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 KDO17563.1 - 0.93 9.1 25.2 1.5 8.4 25.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0565 PF10561.9 KDO17563.1 - 1.4 8.1 8.5 2 7.5 8.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF45 PF01863.17 KDO17563.1 - 3 7.8 15.3 6.3 6.8 15.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 RR_TM4-6 PF06459.12 KDO17563.1 - 3.8 7.3 21.7 6.2 6.6 21.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 KDO17563.1 - 7.2 6.1 33.4 17 4.9 33.4 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit PSI_PsaF PF02507.15 KDO17563.1 - 7.7 6.3 10.3 18 5.1 10.3 1.7 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Rrn6 PF10214.9 KDO17563.1 - 8.2 4.8 31.5 12 4.2 31.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LSM PF01423.22 KDO17564.1 - 1.2e-10 40.9 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SymE_toxin PF08845.10 KDO17564.1 - 0.016 15.2 0.9 0.034 14.2 0.1 1.8 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system EMP24_GP25L PF01105.24 KDO17565.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD VirB8 PF04335.13 KDO17565.1 - 0.14 11.9 0.9 0.2 11.5 0.4 1.5 1 1 0 1 1 1 0 VirB8 protein CDC45 PF02724.14 KDO17566.1 - 3.4e-15 55.4 2.6 3.9e-15 55.2 2.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Isochorismatase PF00857.20 KDO17567.1 - 1.7e-24 87.0 0.0 2.4e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 KDO17568.1 - 4.6e-28 98.6 0.0 6.7e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family AAA PF00004.29 KDO17569.1 - 2.9e-53 179.8 0.0 2.6e-40 137.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO17569.1 - 1.3e-10 41.7 0.5 0.027 14.8 0.1 4.0 2 2 0 3 3 3 3 AAA domain AAA_16 PF13191.6 KDO17569.1 - 1e-09 39.0 0.3 0.00067 20.1 0.1 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KDO17569.1 - 2.1e-07 31.0 0.1 0.0029 17.6 0.1 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KDO17569.1 - 5e-07 29.6 0.0 0.0068 16.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 KDO17569.1 - 8.5e-07 28.8 0.1 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KDO17569.1 - 1.3e-06 28.6 0.0 2.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 KDO17569.1 - 2.2e-06 27.1 0.1 0.0098 15.1 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Mg_chelatase PF01078.21 KDO17569.1 - 3.3e-06 26.7 0.5 0.0031 16.9 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KDO17569.1 - 3.8e-06 26.3 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KDO17569.1 - 1.8e-05 25.0 0.0 0.2 11.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KDO17569.1 - 3.3e-05 23.6 0.1 0.00035 20.3 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 KDO17569.1 - 5.7e-05 22.6 0.1 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 KDO17569.1 - 7.9e-05 22.4 0.0 0.093 12.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO17569.1 - 9.8e-05 21.7 0.1 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 KDO17569.1 - 0.00012 21.6 0.1 5 6.5 0.0 3.9 3 1 1 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 KDO17569.1 - 0.00017 21.9 0.0 0.098 13.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KDO17569.1 - 0.00022 21.0 0.0 0.16 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KDO17569.1 - 0.00022 21.2 1.7 0.3 11.0 0.0 3.3 3 2 1 4 4 3 2 NACHT domain ABC_tran PF00005.27 KDO17569.1 - 0.0003 21.3 0.1 0.02 15.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 KDO17569.1 - 0.0004 20.4 0.0 0.94 9.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KDO17569.1 - 0.00064 19.3 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 KDO17569.1 - 0.00071 19.5 0.2 1.4 8.8 0.0 3.7 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KDO17569.1 - 0.00082 19.4 0.0 0.055 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KDO17569.1 - 0.0015 18.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KDO17569.1 - 0.0018 17.8 0.1 0.87 9.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 KDO17569.1 - 0.0037 17.8 0.0 0.76 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO17569.1 - 0.0041 16.7 4.4 2.1 7.9 0.3 3.8 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.6 KDO17569.1 - 0.007 16.7 0.6 1.6 9.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KDO17569.1 - 0.0073 16.0 0.3 2.8 7.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KDO17569.1 - 0.0093 15.9 0.0 0.064 13.2 0.0 2.2 3 0 0 3 3 2 1 Rad17 P-loop domain ResIII PF04851.15 KDO17569.1 - 0.013 15.5 0.0 8.3 6.4 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KDO17569.1 - 0.017 15.4 0.0 2 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KDO17569.1 - 0.02 15.3 0.0 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KDO17569.1 - 0.024 14.4 0.0 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO17569.1 - 0.03 13.5 0.2 0.52 9.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KDO17569.1 - 0.041 13.6 0.2 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KDO17569.1 - 0.042 13.6 0.0 6.1 6.5 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 KDO17569.1 - 0.055 12.9 0.0 5.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 KDO17569.1 - 0.069 12.4 0.3 4.1 6.5 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 KDO17569.1 - 0.16 11.0 0.0 11 5.0 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 KDO17569.1 - 0.24 11.2 0.9 23 4.7 0.1 3.1 2 2 2 4 4 4 0 DEAD/DEAH box helicase DUF676 PF05057.14 KDO17573.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KDO17573.1 - 0.026 15.1 0.2 0.038 14.6 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 KDO17574.1 - 7.2e-16 58.2 2.5 6e-15 55.2 2.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO17574.1 - 2e-09 37.3 1.4 7.9e-09 35.4 1.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO17574.1 - 0.00013 21.9 1.3 0.025 14.5 0.2 2.0 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KDO17574.1 - 0.0052 16.3 0.1 0.0055 16.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KDO17575.1 - 7.5e-54 182.9 0.0 1.1e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17575.1 - 1.8e-51 175.0 0.0 2.3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO17575.1 - 6.4e-06 26.4 5.7 0.18 12.3 0.2 6.0 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO17575.1 - 0.00015 20.7 0.1 0.00022 20.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO17575.1 - 0.0011 18.3 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FNIP PF05725.12 KDO17575.1 - 0.0092 16.1 7.4 5.2 7.3 0.8 4.9 2 2 1 4 4 4 1 FNIP Repeat APH PF01636.23 KDO17575.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Dabb PF07876.12 KDO17575.1 - 0.059 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain FTA2 PF13095.6 KDO17575.1 - 0.15 11.7 0.0 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SAM_2 PF07647.17 KDO17576.1 - 4.8e-07 29.8 0.0 1.4e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO17576.1 - 3.7e-06 27.3 0.0 6.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CtIP_N PF10482.9 KDO17576.1 - 0.056 13.5 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Pkinase PF00069.25 KDO17577.1 - 3.6e-59 200.3 0.0 1.1e-58 198.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17577.1 - 1.8e-24 86.4 0.0 9.7e-24 84.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17577.1 - 8.7e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO17577.1 - 0.00079 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KDO17577.1 - 0.011 14.7 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KDO17577.1 - 0.037 12.8 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KDO17577.1 - 0.072 12.7 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KDO17577.1 - 0.13 12.1 0.7 0.92 9.4 0.5 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 KDO17578.1 - 8.8e-50 168.7 1.7 8.8e-50 168.7 1.7 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KDO17578.1 - 6.8e-37 126.9 10.5 5.1e-18 65.4 1.4 3.6 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KDO17578.1 - 5.9e-22 77.6 0.0 1.5e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO17578.1 - 4.5e-18 66.3 0.0 2.6e-08 34.4 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KDO17578.1 - 3.7e-05 23.6 3.4 0.0028 17.5 0.3 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO17578.1 - 0.0055 16.4 0.0 0.067 12.9 0.0 2.4 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus MORN PF02493.20 KDO17580.1 - 3.9e-63 205.7 115.6 8.9e-07 28.4 1.0 18.3 19 0 0 19 19 19 15 MORN repeat BT1 PF03092.16 KDO17581.1 - 4.3e-14 51.6 11.4 4.7e-14 51.5 0.9 2.3 2 0 0 2 2 2 2 BT1 family AphA_like PF14557.6 KDO17582.1 - 0.35 10.6 3.2 30 4.3 0.0 4.0 4 0 0 4 4 4 0 Putative AphA-like transcriptional regulator TPR_19 PF14559.6 KDO17583.1 - 2.9e-10 40.5 20.6 4.2e-06 27.2 0.7 6.4 6 2 2 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO17583.1 - 1.4e-07 31.7 25.0 0.0091 16.2 0.9 5.7 5 2 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KDO17583.1 - 3.7e-05 24.2 18.9 0.0041 17.8 1.9 6.7 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO17583.1 - 5.4e-05 23.0 24.7 0.44 10.8 0.1 7.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO17583.1 - 9.1e-05 23.0 14.8 0.0032 18.1 0.3 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO17583.1 - 0.0014 18.8 16.8 0.12 12.7 1.4 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO17583.1 - 0.0031 17.6 7.5 0.29 11.3 1.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO17583.1 - 0.0042 17.0 6.5 5.4 7.3 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KDO17583.1 - 0.0057 16.1 3.4 0.034 13.6 1.0 3.0 2 2 1 4 4 4 1 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 KDO17583.1 - 0.06 13.0 5.4 11 5.6 0.1 4.6 3 2 2 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) SRP_TPR_like PF17004.5 KDO17583.1 - 0.084 12.9 8.8 0.042 13.9 0.8 3.3 4 0 0 4 4 4 0 Putative TPR-like repeat TPR_8 PF13181.6 KDO17583.1 - 0.084 13.1 7.8 7.9 7.0 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO17583.1 - 0.11 12.4 0.3 0.11 12.4 0.3 7.3 7 1 1 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO17583.1 - 0.14 12.3 5.3 7.2 6.8 0.5 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat EnY2 PF10163.9 KDO17584.1 - 7.3e-14 51.9 0.9 9.3e-14 51.6 0.7 1.3 1 1 0 1 1 1 1 Transcription factor e(y)2 DUF4090 PF13319.6 KDO17584.1 - 0.017 15.3 0.1 0.018 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) LRR_6 PF13516.6 KDO17585.1 - 0.17 12.0 0.5 12 6.2 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich repeat DUF3499 PF12005.8 KDO17587.1 - 0.0078 16.8 0.2 0.047 14.3 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3499) Ras PF00071.22 KDO17588.1 - 5.1e-75 250.5 0.0 8.4e-40 136.0 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KDO17588.1 - 7.2e-49 165.0 0.0 2.4e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO17588.1 - 5.2e-15 55.3 0.0 4e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KDO17588.1 - 7e-06 26.0 0.4 1.1 9.1 0.0 4.0 4 0 0 4 4 4 1 RsgA GTPase Gtr1_RagA PF04670.12 KDO17588.1 - 1.1e-05 24.9 0.0 0.061 12.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region ArgoMid PF16487.5 KDO17588.1 - 1.3e-05 25.3 0.3 0.13 12.5 0.1 2.4 2 0 0 2 2 2 2 Mid domain of argonaute MMR_HSR1 PF01926.23 KDO17588.1 - 1.9e-05 24.7 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO17588.1 - 0.0019 17.7 0.0 0.23 11.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KDO17588.1 - 0.0033 17.8 0.0 0.24 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KDO17588.1 - 0.012 15.1 0.1 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO17588.1 - 0.025 15.0 0.3 17 5.8 0.0 3.5 2 2 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KDO17588.1 - 0.027 14.6 0.1 5.2 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KDO17588.1 - 0.039 13.1 0.3 32 3.5 0.1 3.5 3 1 1 4 4 4 0 G-protein alpha subunit OKR_DC_1_N PF03709.15 KDO17588.1 - 0.052 13.8 0.1 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_29 PF13555.6 KDO17588.1 - 0.068 12.9 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KDO17588.1 - 0.17 11.6 0.1 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KDO17588.1 - 0.18 12.1 0.0 8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KDO17588.1 - 0.27 11.1 0.4 24 4.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain zf-C3HC4 PF00097.25 KDO17589.1 - 2.2e-09 37.0 3.0 3.4e-09 36.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO17589.1 - 6.9e-09 35.4 6.6 2.6e-08 33.6 6.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO17589.1 - 2.8e-08 34.0 5.4 4.2e-08 33.4 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO17589.1 - 7.9e-08 32.2 1.7 7.9e-08 32.2 1.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO17589.1 - 2e-07 30.9 2.9 2.8e-07 30.4 2.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO17589.1 - 3.1e-06 27.2 1.0 4.9e-06 26.5 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO17589.1 - 7.6e-06 25.7 4.0 1.1e-05 25.2 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO17589.1 - 3.1e-05 24.0 4.7 5.2e-05 23.3 4.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KDO17589.1 - 9.4e-05 22.6 3.8 0.00033 20.9 4.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KDO17589.1 - 0.00079 19.2 1.2 0.0016 18.2 1.2 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KDO17589.1 - 0.0016 18.3 5.9 0.0057 16.5 1.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 KDO17589.1 - 0.013 15.3 0.3 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-CRD PF17979.1 KDO17589.1 - 0.017 15.3 2.2 0.035 14.2 2.1 1.6 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions DUF1244 PF06844.11 KDO17589.1 - 0.18 12.0 0.7 2.1 8.6 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1244) DZR PF12773.7 KDO17589.1 - 0.19 11.8 2.7 1.4 9.0 2.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 KDO17589.1 - 0.26 11.1 7.6 3.4 7.5 8.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KDO17589.1 - 1.5 9.1 6.1 10 6.4 0.0 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain PAN_4 PF14295.6 KDO17592.1 - 1.9e-14 53.3 16.1 1.9e-07 30.9 4.6 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 KDO17592.1 - 1.5e-13 50.5 11.7 4.3e-07 29.8 2.9 2.6 2 1 1 3 3 3 2 PAN domain PAN_2 PF08276.11 KDO17592.1 - 0.026 14.6 4.0 0.026 14.6 4.0 2.4 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.12 KDO17592.1 - 0.056 13.3 13.3 0.7 9.7 4.3 2.3 2 0 0 2 2 2 0 PAN-like domain Med3 PF11593.8 KDO17592.1 - 0.69 9.0 2.4 0.89 8.7 2.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ABC2_membrane PF01061.24 KDO17593.1 - 1.2e-39 135.9 17.6 1.6e-39 135.5 17.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO17593.1 - 1.1e-26 94.0 0.0 1.6e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO17593.1 - 9.1e-07 29.0 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KDO17593.1 - 7.7e-05 22.0 19.8 0.00016 20.9 19.8 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KDO17593.1 - 9.7e-05 22.3 0.1 0.00017 21.6 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO17593.1 - 0.0022 17.7 0.2 0.0053 16.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO17593.1 - 0.0028 18.0 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KDO17593.1 - 0.0053 16.2 0.1 0.09 12.2 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KDO17593.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KDO17593.1 - 0.093 12.3 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KDO17593.1 - 0.14 11.4 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC2_membrane_2 PF12679.7 KDO17593.1 - 5.8 6.1 9.6 12 5.0 9.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_membrane PF00664.23 KDO17594.1 - 7.3e-51 173.4 5.5 1.3e-50 172.6 5.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO17594.1 - 4.7e-17 62.8 0.0 8.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KDO17594.1 - 0.0044 16.7 0.6 0.012 15.4 0.3 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO17594.1 - 0.022 14.4 0.1 0.052 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KDO17594.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 KDO17594.1 - 0.025 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KDO17594.1 - 0.058 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KDO17594.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO17594.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO17594.1 - 0.11 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO17594.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KDO17594.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 KDO17594.1 - 0.23 11.2 0.0 0.32 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KDO17594.1 - 0.23 11.5 0.1 0.36 10.9 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain MutS_V PF00488.21 KDO17595.1 - 5.2e-75 251.6 0.7 9e-75 250.8 0.7 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KDO17595.1 - 1e-34 119.1 0.0 2.5e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KDO17595.1 - 6e-33 114.7 1.1 3.4e-32 112.2 0.9 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KDO17595.1 - 2.9e-11 43.5 0.0 6.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KDO17595.1 - 2.7e-06 27.7 0.0 1.2e-05 25.7 0.0 2.0 1 1 1 2 2 2 1 MutS domain II AAA_27 PF13514.6 KDO17595.1 - 0.028 14.0 0.0 0.36 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 KDO17596.1 - 0.00019 21.3 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO17596.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain UCH PF00443.29 KDO17597.1 - 5.8e-28 98.1 0.0 8.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 KDO17602.1 - 0.00018 22.1 0.8 0.078 13.6 0.9 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17602.1 - 0.0005 20.6 2.0 2.3 8.9 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17602.1 - 0.013 15.9 7.3 6.6 7.7 0.1 5.1 5 1 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 KDO17602.1 - 0.15 12.5 2.4 1.2 9.5 0.0 3.2 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Na_Pi_cotrans PF02690.15 KDO17603.1 - 2.5e-37 128.1 18.0 5.3e-20 71.9 6.0 2.8 3 0 0 3 3 3 2 Na+/Pi-cotransporter RhodobacterPufX PF11511.8 KDO17603.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.3 3 0 0 3 3 3 0 Intrinsic membrane protein PufX RRP14 PF15459.6 KDO17604.1 - 2.7e-07 31.1 1.0 2.7e-07 31.1 1.0 2.1 2 0 0 2 2 2 1 60S ribosome biogenesis protein Rrp14 REC1 PF18501.1 KDO17605.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha helical recognition lobe domain GMP_PDE_delta PF05351.11 KDO17606.1 - 9.3e-61 204.5 0.3 1.3e-60 204.0 0.3 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit SET PF00856.28 KDO17607.1 - 5.6e-10 39.9 0.1 4.5e-07 30.4 0.0 2.2 1 1 1 2 2 2 2 SET domain zf-MYND PF01753.18 KDO17607.1 - 9.3e-07 28.8 9.6 9.3e-07 28.8 9.6 2.1 2 0 0 2 2 2 1 MYND finger Pkinase PF00069.25 KDO17608.1 - 7.8e-66 222.1 0.0 9.3e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17608.1 - 4.4e-44 150.7 0.0 5.6e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17608.1 - 2.9e-07 30.1 0.0 1.1e-05 24.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO17608.1 - 3.9e-06 25.9 0.0 5.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO17608.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO17608.1 - 0.051 13.5 0.0 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO17608.1 - 0.11 11.4 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Nop16 PF09420.10 KDO17609.1 - 0.0034 17.4 0.0 0.0044 17.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Mg_trans_NIPA PF05653.14 KDO17611.1 - 3.5e-12 46.1 9.9 6e-12 45.3 9.9 1.3 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KDO17611.1 - 0.0034 17.6 22.7 0.029 14.6 1.6 3.2 2 1 0 2 2 2 2 EamA-like transporter family DUF2101 PF09874.9 KDO17611.1 - 0.022 14.5 0.2 0.061 13.0 0.2 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) UPF0242 PF06785.11 KDO17611.1 - 0.12 12.5 1.0 0.23 11.5 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF308 PF03729.13 KDO17611.1 - 1.9 8.9 17.3 2.4 8.5 4.0 3.3 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4231 PF14015.6 KDO17611.1 - 2.1 8.9 4.8 1.9 9.0 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_A8 PF01252.18 KDO17611.1 - 5.4 7.3 7.2 14 5.9 5.4 2.5 1 1 1 2 2 2 0 Signal peptidase (SPase) II vATP-synt_E PF01991.18 KDO17613.1 - 0.041 13.3 0.0 0.045 13.2 0.0 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF4619 PF15398.6 KDO17614.1 - 0.059 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) rve_3 PF13683.6 KDO17614.1 - 0.077 12.8 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain Viral_Rep PF02407.16 KDO17614.1 - 0.11 12.7 0.4 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 Putative viral replication protein HU-CCDC81_euk_2 PF18289.1 KDO17615.1 - 1.9e-12 47.1 0.0 5.7e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 KDO17615.1 - 1.7e-07 31.3 0.1 2.1e-06 27.8 0.1 2.5 1 1 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Bac_DNA_binding PF00216.21 KDO17615.1 - 0.0067 16.6 0.0 5.8 7.2 0.0 3.0 3 0 0 3 3 3 2 Bacterial DNA-binding protein Peroxidase_2 PF01328.17 KDO17617.1 - 5.9e-34 118.2 0.0 7.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EFhand_Ca_insen PF08726.10 KDO17617.1 - 0.034 14.2 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand TMEM151 PF14857.6 KDO17619.1 - 0.15 10.9 0.2 0.18 10.7 0.2 1.1 1 0 0 1 1 1 0 TMEM151 family DUF3165 PF11364.8 KDO17619.1 - 0.7 10.3 11.4 1.4 9.3 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3165) DUF2273 PF10031.9 KDO17619.1 - 1.2 9.2 0.1 1.2 9.2 0.1 4.4 4 1 0 4 4 4 0 Small integral membrane protein (DUF2273) DHHC PF01529.20 KDO17619.1 - 4 7.5 5.8 1.1 9.3 2.2 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase ZZ PF00569.17 KDO17621.1 - 6.6e-35 118.7 18.5 3e-08 33.4 0.4 6.2 6 0 0 6 6 6 6 Zinc finger, ZZ type Cytochrome_C554 PF13435.6 KDO17621.1 - 0.31 12.0 0.1 0.31 12.0 0.1 4.5 4 1 2 6 6 6 0 Cytochrome c554 and c-prime Sugar_tr PF00083.24 KDO17623.1 - 8e-106 354.6 23.7 9.1e-106 354.4 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO17623.1 - 1.2e-26 93.5 41.4 1.6e-18 66.8 16.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KDO17623.1 - 0.0072 14.9 3.0 0.0072 14.9 3.0 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.24 KDO17624.1 - 5.4e-105 351.9 27.0 6.3e-105 351.6 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO17624.1 - 3.4e-29 101.9 28.9 5.1e-21 75.0 6.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO17625.1 - 2.4e-32 112.4 12.6 2.6e-32 112.3 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO17625.1 - 3.4e-09 36.1 5.7 4.1e-09 35.8 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM100 PF16311.5 KDO17625.1 - 1.5 8.4 6.2 2.6 7.6 2.7 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 Redoxin PF08534.10 KDO17626.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin FYVE PF01363.21 KDO17627.1 - 9.1e-06 25.7 6.7 1.7e-05 24.9 6.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 KDO17627.1 - 0.0013 19.1 1.9 0.0027 18.0 1.9 1.6 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 KDO17627.1 - 0.17 11.8 2.8 0.42 10.5 2.8 1.6 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.24 KDO17627.1 - 5.3 7.3 9.1 0.76 10.0 4.5 1.9 2 0 0 2 2 2 0 B-box zinc finger FMN_bind_2 PF04299.12 KDO17628.1 - 7.8e-49 165.6 0.0 9.5e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF5316 PF17247.2 KDO17629.1 - 0.16 12.0 0.1 0.49 10.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5316) K-cyclin_vir_C PF09080.10 KDO17629.1 - 0.39 11.2 3.8 2.1 8.8 0.6 2.9 3 1 0 3 3 3 0 K cyclin, C terminal Guanylate_cyc PF00211.20 KDO17630.1 - 3.7e-05 23.4 0.0 0.00064 19.4 0.0 2.2 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 KDO17630.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M17 PF00883.21 KDO17631.1 - 4e-62 210.3 0.4 4.5e-62 210.1 0.4 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17 PF00883.21 KDO17633.1 - 3.5e-66 223.6 1.7 4.5e-66 223.2 1.7 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KDO17633.1 - 3e-16 59.8 0.0 6.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 tRNA_lig_CPD PF08302.11 KDO17634.1 - 0.0035 16.8 0.0 0.0079 15.7 0.0 1.5 1 1 1 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain TPR_1 PF00515.28 KDO17635.1 - 1.2e-22 78.7 0.0 1.8e-06 27.5 0.0 4.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO17635.1 - 1.4e-18 65.4 0.0 4.1e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO17635.1 - 1.3e-13 50.4 0.0 9.4e-08 31.6 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KDO17635.1 - 6.4e-10 38.4 0.0 0.16 12.2 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO17635.1 - 1.2e-08 35.4 0.0 0.00016 22.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO17635.1 - 1.3e-07 31.5 0.0 0.0086 16.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO17635.1 - 2.4e-07 30.8 0.1 4e-05 23.7 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO17635.1 - 5.6e-07 29.1 0.1 0.03 14.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17635.1 - 4.3e-06 27.1 0.0 1.6 9.7 0.0 4.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO17635.1 - 3.1e-05 24.2 0.5 0.75 10.1 0.0 3.3 1 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO17635.1 - 9.2e-05 22.4 0.0 0.18 11.9 0.0 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.15 KDO17635.1 - 0.0033 17.5 0.3 0.38 10.8 0.5 2.5 2 0 0 2 2 2 1 MAS20 protein import receptor TPR_19 PF14559.6 KDO17635.1 - 0.0063 17.0 7.8 0.89 10.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Spore_III_AB PF09548.10 KDO17635.1 - 0.13 12.3 0.8 0.33 11.0 0.8 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RXT2_N PF08595.11 KDO17635.1 - 9.3 6.3 9.3 8.3 6.4 2.6 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-RanBP PF00641.18 KDO17636.1 - 2.1e-08 33.3 1.9 4.4e-08 32.3 1.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 KDO17636.1 - 0.0027 17.7 1.2 0.0032 17.4 0.3 1.6 2 0 0 2 2 2 1 Double zinc ribbon CpXC PF14353.6 KDO17636.1 - 0.016 15.2 0.5 0.023 14.8 0.4 1.4 1 1 0 1 1 1 0 CpXC protein Rubredoxin_2 PF18073.1 KDO17636.1 - 0.02 14.6 0.7 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Vps36-NZF-N PF16988.5 KDO17636.1 - 0.032 13.6 1.4 0.27 10.7 1.4 2.2 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Mito_carr PF00153.27 KDO17637.1 - 1.3e-24 85.9 0.1 2.6e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein 5_nucleotid_C PF02872.18 KDO17639.1 - 2.8e-17 63.4 0.0 5.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KDO17639.1 - 0.057 13.9 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Pkinase_Tyr PF07714.17 KDO17642.1 - 1.1e-54 185.4 0.0 1.4e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17642.1 - 4.1e-53 180.4 0.0 5.3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO17642.1 - 0.0033 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO17642.1 - 0.012 14.9 0.0 0.026 13.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RyR PF02026.16 KDO17643.1 - 3.8e-43 145.6 0.0 1.1e-20 73.6 0.0 2.4 2 0 0 2 2 2 2 RyR domain Pkinase PF00069.25 KDO17643.1 - 5.6e-34 117.7 0.0 7.9e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17643.1 - 9.1e-15 54.6 0.0 2.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO17643.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO17643.1 - 6.6e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO17643.1 - 0.034 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family HrpB7 PF09486.10 KDO17644.1 - 0.0068 16.8 0.9 0.0089 16.4 0.4 1.5 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) Ysc84 PF04366.12 KDO17646.1 - 6.9e-21 74.3 0.2 3.5e-16 59.1 0.0 2.6 2 0 0 2 2 2 2 Las17-binding protein actin regulator FYVE PF01363.21 KDO17646.1 - 3.3e-13 49.6 5.1 3.3e-13 49.6 5.1 3.1 3 1 0 3 3 3 1 FYVE zinc finger zf-ribbon_3 PF13248.6 KDO17646.1 - 0.0018 17.6 1.0 0.0018 17.6 1.0 3.9 4 1 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KDO17646.1 - 0.0023 17.6 4.9 0.0023 17.6 4.9 3.9 5 0 0 5 5 5 1 zinc-ribbon domain DZR PF12773.7 KDO17646.1 - 0.016 15.2 0.7 0.016 15.2 0.7 4.3 3 1 0 3 3 3 0 Double zinc ribbon Prok-RING_2 PF14445.6 KDO17646.1 - 0.029 14.5 3.5 0.029 14.5 3.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 DUF778 PF05608.12 KDO17647.1 - 1.7e-06 28.6 1.5 1.7e-06 28.6 1.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF778) Ribosomal_L7Ae PF01248.26 KDO17649.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PEP-utilizers PF00391.23 KDO17649.1 - 0.017 14.8 0.7 0.056 13.2 0.7 1.9 2 1 0 2 2 2 0 PEP-utilising enzyme, mobile domain TPP_enzyme_C PF02775.21 KDO17649.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RNase_P_pop3 PF08228.11 KDO17649.1 - 0.07 13.2 0.2 0.088 12.8 0.2 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Asp_Arg_Hydrox PF05118.15 KDO17650.1 - 2.6e-43 147.6 0.0 4.5e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 KDO17650.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUSP PF06337.12 KDO17651.1 - 0.00024 21.6 0.0 0.00064 20.3 0.0 1.8 1 1 0 1 1 1 1 DUSP domain TRP PF06011.12 KDO17652.1 - 1.2e-08 34.1 1.7 1.2e-08 34.1 1.7 2.0 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel TipAS PF07739.13 KDO17653.1 - 0.15 12.6 0.3 0.3 11.6 0.3 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain LapA_dom PF06305.11 KDO17655.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HemY_N PF07219.13 KDO17656.1 - 0.021 15.0 1.0 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 HemY protein N-terminus Nop53 PF07767.11 KDO17656.1 - 0.67 9.3 6.6 0.89 8.9 6.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PLAC9 PF15205.6 KDO17659.1 - 0.015 15.7 0.0 0.015 15.7 0.0 1.8 2 0 0 2 2 2 0 Placenta-specific protein 9 VPS9 PF02204.18 KDO17660.1 - 2.1e-05 24.7 0.0 2.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain gpW PF02831.15 KDO17661.1 - 0.13 12.2 3.2 0.11 12.4 0.4 2.5 2 0 0 2 2 2 0 gpW DUF1664 PF07889.12 KDO17661.1 - 0.2 11.7 9.1 4.6 7.3 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Pox_Ag35 PF03286.14 KDO17661.1 - 0.25 11.1 1.7 0.65 9.8 1.7 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CLZ PF16526.5 KDO17661.1 - 0.33 11.4 9.2 2.3 8.6 0.4 4.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 KDO17661.1 - 0.72 9.9 22.9 0.073 13.2 6.4 3.7 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KDO17661.1 - 1.2 9.3 8.5 5.4 7.2 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KDO17661.1 - 1.5 9.1 5.4 3 8.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 KDO17661.1 - 5.8 7.4 15.4 2 8.9 4.0 3.1 2 0 0 2 2 2 0 Cell division protein ZapB TolA_bind_tri PF16331.5 KDO17661.1 - 6.2 7.0 12.1 8.1 6.6 3.6 3.6 3 0 0 3 3 3 0 TolA binding protein trimerisation Syntaxin-6_N PF09177.11 KDO17661.1 - 7.9 7.1 13.0 13 6.4 0.9 3.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Peptidase_C26 PF07722.13 KDO17663.1 - 3.2e-24 85.9 0.0 7.4e-23 81.4 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 GATase PF00117.28 KDO17663.1 - 5.3e-13 49.2 0.0 7.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KDO17663.1 - 0.048 13.5 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 SNO glutamine amidotransferase family GRDP-like PF07173.12 KDO17664.1 - 6.1e-13 49.6 0.6 1.2e-12 48.7 0.6 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Tyrosinase PF00264.20 KDO17665.1 - 1e-20 75.0 0.8 2.3e-20 73.8 0.1 1.8 2 1 0 2 2 2 1 Common central domain of tyrosinase DAP3 PF10236.9 KDO17665.1 - 0.093 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Tyrosinase PF00264.20 KDO17666.1 - 1.1e-22 81.4 0.2 2.1e-22 80.5 0.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Mannosyl_trans3 PF11051.8 KDO17667.1 - 9.6e-33 113.7 0.0 6.9e-32 110.9 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative MCM_bind PF09739.9 KDO17667.1 - 0.19 10.1 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PIF1 PF05970.14 KDO17668.1 - 3.5e-30 105.4 0.0 1.7e-29 103.1 0.0 1.9 1 1 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KDO17668.1 - 0.00066 17.7 0.0 0.0011 17.0 0.0 1.3 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KDO17668.1 - 0.00073 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1191 PF06697.12 KDO17669.1 - 0.83 9.4 4.7 6.5 6.5 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1191) DUF1522 PF07482.11 KDO17670.1 - 0.14 12.5 0.2 0.22 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) DUF2079 PF09852.9 KDO17670.1 - 0.73 8.6 2.0 0.91 8.3 2.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) BRCT_2 PF16589.5 KDO17671.1 - 1.5e-11 44.5 0.0 1.9e-07 31.4 0.0 2.8 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KDO17671.1 - 6.6e-10 38.8 0.0 1.6e-06 27.9 0.0 2.8 2 1 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 KDO17671.1 - 0.0056 17.0 0.0 0.8 10.1 0.0 3.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KDO17671.1 - 0.1 12.9 0.0 3.8 7.9 0.0 2.6 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain SWIB PF02201.18 KDO17671.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 SWIB/MDM2 domain Kinesin PF00225.23 KDO17672.1 - 1.5e-52 178.6 0.9 1.7e-52 178.5 0.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF2232 PF09991.9 KDO17673.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FYVE PF01363.21 KDO17674.1 - 3.8e-16 59.0 7.6 7.1e-16 58.1 7.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO17674.1 - 0.016 15.4 4.8 0.032 14.4 4.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 KDO17674.1 - 0.64 9.9 12.0 0.051 13.5 7.1 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO17674.1 - 3.4 7.7 11.6 7 6.7 11.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CHORD PF04968.12 KDO17677.1 - 0.0016 19.1 3.3 0.004 17.9 3.3 1.6 1 0 0 1 1 1 1 CHORD MAGE PF01454.19 KDO17678.1 - 3.3e-08 33.5 0.0 3.8e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 MAGE family CENP-T_C PF15511.6 KDO17679.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO17679.1 - 9e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO17679.1 - 0.00044 20.4 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO17679.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO17679.1 - 0.0024 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO17679.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO17679.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KDO17680.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO17680.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO17680.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO17680.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO17680.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO17680.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO17680.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated APG6 PF04111.12 KDO17682.1 - 2.2e-52 177.6 0.0 3.3e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KDO17682.1 - 0.0003 21.3 3.1 0.46 11.0 2.9 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region NleF_casp_inhib PF16809.5 KDO17689.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor Ank_2 PF12796.7 KDO17690.1 - 1e-27 96.5 0.0 1.9e-11 44.4 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO17690.1 - 5.7e-17 61.6 0.4 3.9e-07 30.2 0.1 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17690.1 - 1.4e-16 60.6 0.0 6.7e-08 32.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17690.1 - 8e-15 53.5 0.2 0.0017 18.7 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO17690.1 - 1.5e-12 47.3 0.5 0.018 15.5 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat FYVE PF01363.21 KDO17690.1 - 0.002 18.2 8.7 0.0048 17.0 8.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Cytochrom_CIII PF02085.16 KDO17690.1 - 0.0022 18.3 2.9 0.004 17.5 2.9 1.4 1 0 0 1 1 1 1 Class III cytochrome C family Cytochrom_c3_2 PF14537.6 KDO17690.1 - 0.0031 17.9 0.6 0.0031 17.9 0.6 1.9 2 0 0 2 2 2 1 Cytochrome c3 PSCyt3 PF07627.11 KDO17690.1 - 0.0035 17.6 4.2 0.045 14.0 0.0 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1588) Siva PF05458.12 KDO17690.1 - 0.041 13.6 6.2 0.068 12.9 6.2 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Cytochrome_C7 PF14522.6 KDO17690.1 - 2.1 8.4 11.5 9.4 6.3 11.6 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c cobW PF02492.19 KDO17692.1 - 3.8e-36 124.3 0.9 5.1e-36 123.9 0.9 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KDO17692.1 - 0.00021 21.2 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 KDO17692.1 - 0.00094 19.0 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KDO17692.1 - 0.0015 18.4 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO17692.1 - 0.0074 15.9 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_19 PF13245.6 KDO17692.1 - 0.0074 16.6 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KDO17692.1 - 0.0081 16.2 0.0 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KDO17692.1 - 0.009 16.4 0.1 0.06 13.7 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KDO17692.1 - 0.0093 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO17692.1 - 0.014 15.6 0.6 0.08 13.1 0.6 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KDO17692.1 - 0.026 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KDO17692.1 - 0.028 14.7 0.1 0.12 12.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO17692.1 - 0.06 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KDO17692.1 - 0.066 13.0 1.8 0.16 11.7 1.8 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KDO17692.1 - 0.079 12.7 0.0 0.3 10.9 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KDO17692.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NKAIN PF05640.14 KDO17692.1 - 0.099 11.9 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein Myotub-related PF06602.14 KDO17693.1 - 1.2e-118 396.1 0.0 1.6e-118 395.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain RabGAP-TBC PF00566.18 KDO17693.1 - 5.1e-28 98.2 0.0 2.3e-26 92.8 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 KDO17693.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO17693.1 - 0.00013 22.3 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRAM PF02893.20 KDO17693.1 - 0.042 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 GRAM domain IRK_C PF17655.1 KDO17694.1 - 2.6e-20 72.7 0.5 9.7e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KDO17694.1 - 4.5e-11 42.7 7.6 7.3e-09 35.6 7.6 2.4 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain SAC3_GANP PF03399.16 KDO17694.1 - 0.046 13.1 0.2 0.075 12.4 0.2 1.2 1 0 0 1 1 1 0 SAC3/GANP family Ion_trans_2 PF07885.16 KDO17694.1 - 1.5 8.8 12.3 2.8 8.0 11.4 1.9 1 1 1 2 2 2 0 Ion channel Linker_histone PF00538.19 KDO17695.1 - 4e-17 62.3 0.2 4e-17 62.3 0.2 3.1 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 KDO17695.1 - 7.5e-08 32.7 80.2 7.5e-08 32.7 80.2 2.2 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 PTEN_C2 PF10409.9 KDO17696.1 - 1.8e-08 34.2 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PI3_PI4_kinase PF00454.27 KDO17697.1 - 3.7e-27 95.7 0.0 1.5e-26 93.7 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KDO17697.1 - 2.4e-05 24.0 0.0 6.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 FATC domain EF-hand_1 PF00036.32 KDO17699.1 - 4.2e-20 69.7 3.4 5.3e-05 22.5 0.0 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KDO17699.1 - 1.6e-18 66.9 0.5 5.6e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO17699.1 - 1.6e-17 61.9 5.8 0.0024 17.7 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO17699.1 - 5.7e-13 47.7 4.9 0.0095 15.4 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KDO17699.1 - 5.4e-09 35.8 6.0 6.9e-06 25.8 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 KDO17699.1 - 0.085 13.1 0.0 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Dockerin type I domain IQ PF00612.27 KDO17699.1 - 0.5 10.3 8.1 0.13 12.1 3.7 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif EF-hand_7 PF13499.6 KDO17700.1 - 5.2e-21 74.9 3.5 7.3e-11 42.4 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO17700.1 - 2.6e-20 70.6 3.0 0.00016 21.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 KDO17700.1 - 5.9e-20 69.3 8.2 1.5e-07 30.4 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 KDO17700.1 - 4.8e-19 66.9 5.8 4.5e-05 22.7 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KDO17700.1 - 3.2e-15 55.7 6.1 4.8e-11 42.3 0.4 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO17700.1 - 0.002 18.4 0.1 2.2 8.6 0.0 3.2 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KDO17700.1 - 0.0024 18.0 4.2 1.9 8.7 0.4 4.4 4 0 0 4 4 4 1 Dockerin type I domain HU-CCDC81_euk_2 PF18289.1 KDO17701.1 - 8.9e-06 25.8 0.1 2.1e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 Mlo PF03094.15 KDO17704.1 - 1.6e-05 23.5 0.4 0.028 12.8 0.0 2.1 2 0 0 2 2 2 2 Mlo family DUF996 PF06195.13 KDO17704.1 - 0.00097 19.4 0.9 0.0072 16.6 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF996) Yip1 PF04893.17 KDO17704.1 - 0.0066 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Yip1 domain Viral_Beta_CD PF04530.12 KDO17704.1 - 0.025 14.9 0.1 5.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family Gaa1 PF04114.14 KDO17704.1 - 0.026 13.6 3.0 0.035 13.1 3.0 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component GWT1 PF06423.12 KDO17704.1 - 0.036 14.2 1.4 0.1 12.7 0.9 1.9 1 1 1 2 2 2 0 GWT1 DUF4064 PF13273.6 KDO17704.1 - 0.038 14.3 7.9 2 8.8 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF5362 PF17319.2 KDO17704.1 - 0.058 13.2 4.0 1.9 8.4 0.1 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5362) MFS_2 PF13347.6 KDO17704.1 - 0.063 11.8 3.7 0.81 8.2 2.7 2.0 1 1 1 2 2 2 0 MFS/sugar transport protein OppC_N PF12911.7 KDO17704.1 - 0.078 13.0 0.2 17 5.5 0.0 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C RAMP4 PF06624.12 KDO17704.1 - 0.086 12.9 0.3 0.24 11.5 0.1 1.9 1 1 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF3671 PF12420.8 KDO17704.1 - 0.089 12.9 1.7 18 5.4 4.5 2.2 1 1 1 2 2 2 0 Protein of unknown function ABG_transport PF03806.13 KDO17704.1 - 0.12 10.6 2.4 0.29 9.3 2.6 1.5 1 1 0 1 1 1 0 AbgT putative transporter family Orf78 PF06024.12 KDO17704.1 - 0.2 12.0 0.7 22 5.4 0.2 2.3 2 0 0 2 2 2 0 Orf78 (ac78) EI24 PF07264.11 KDO17704.1 - 0.76 10.0 5.3 1.8 8.8 5.1 1.8 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) CbtA PF09490.10 KDO17704.1 - 3.3 7.4 6.4 33 4.1 6.4 2.0 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF3522 PF12036.8 KDO17705.1 - 4.6e-26 92.3 11.0 8.9e-26 91.3 11.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) EGF_2 PF07974.13 KDO17705.1 - 0.057 13.8 7.6 0.13 12.6 7.6 1.6 1 0 0 1 1 1 0 EGF-like domain D_CNTX PF17492.2 KDO17705.1 - 5.7 7.2 6.5 5.7 7.2 3.6 2.3 2 0 0 2 2 2 0 Delta Ctenitoxins Pox_LP_H2 PF03356.15 KDO17706.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Viral late protein H2 CTV_P6 PF06706.11 KDO17706.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein CPSase_L_D3 PF02787.19 KDO17706.1 - 1.8 8.9 5.1 37 4.7 0.1 3.4 3 0 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HA PF03457.14 KDO17707.1 - 1.6e-08 34.8 0.0 0.0055 17.0 0.0 2.1 2 0 0 2 2 2 2 Helicase associated domain HA PF03457.14 KDO17708.1 - 4.7e-10 39.6 0.1 0.015 15.6 0.0 4.4 4 0 0 4 4 4 4 Helicase associated domain HA PF03457.14 KDO17709.1 - 1.2e-26 92.8 0.0 6.6e-07 29.6 0.0 7.6 8 1 1 9 9 9 3 Helicase associated domain HA PF03457.14 KDO17710.1 - 1e-17 64.2 0.0 1.8e-06 28.2 0.0 4.6 5 0 0 5 5 5 4 Helicase associated domain BET PF17035.5 KDO17712.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation P53_tetramer PF07710.11 KDO17712.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 P53 tetramerisation motif Ribosomal_L16 PF00252.18 KDO17713.1 - 6.2e-38 129.8 0.0 8e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L15e PF00827.17 KDO17714.1 - 2.6e-19 69.7 1.2 2.8e-19 69.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Myb_DNA-binding PF00249.31 KDO17715.1 - 1.3e-12 47.7 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO17715.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 KDO17716.1 - 5e-08 32.7 0.0 6.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.31 KDO17717.1 - 1.4e-11 44.4 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain COMM_domain PF07258.14 KDO17717.1 - 4.8e-05 23.4 0.0 9.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 COMM domain DUF3022 PF11226.8 KDO17717.1 - 0.044 14.2 0.3 0.088 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Tmemb_161AB PF10268.9 KDO17718.1 - 8e-42 143.5 0.4 1e-41 143.1 0.4 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Anticodon_1 PF08264.13 KDO17719.1 - 2.4e-39 134.7 0.0 3.3e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 KDO17720.1 - 8e-07 29.3 1.4 1.5e-06 28.4 1.1 1.5 1 1 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Inhibitor_Mig-6 PF11555.8 KDO17720.1 - 0.16 12.1 0.5 0.21 11.7 0.5 1.4 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 TPR_1 PF00515.28 KDO17722.1 - 3.6e-29 99.3 9.7 0.00041 20.0 0.0 9.4 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KDO17722.1 - 4.3e-22 76.4 12.8 0.00077 19.4 0.0 7.9 9 1 0 9 9 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO17722.1 - 1.2e-15 56.9 2.8 3.6e-05 23.3 0.0 5.9 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.6 KDO17722.1 - 1e-14 53.4 6.9 0.0068 16.5 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KDO17722.1 - 4.5e-11 43.2 0.7 0.016 15.9 0.1 4.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO17722.1 - 1.1e-10 41.7 5.3 0.002 18.4 0.3 4.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO17722.1 - 1.4e-09 37.7 2.0 0.0076 16.6 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO17722.1 - 6.7e-09 35.8 2.7 0.017 15.3 0.0 5.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO17722.1 - 0.00058 20.3 0.0 0.55 10.8 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO17722.1 - 0.00059 19.7 2.3 75 3.7 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17722.1 - 0.001 19.7 2.1 37 5.5 0.0 6.7 3 2 4 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO17722.1 - 0.038 14.2 5.2 0.042 14.1 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Vta1_C PF18097.1 KDO17722.1 - 0.095 12.4 0.0 1.1 9.0 0.0 2.8 2 0 0 2 2 2 0 Vta1 C-terminal domain NARP1 PF12569.8 KDO17722.1 - 0.11 11.4 1.6 3.1 6.6 0.1 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 KDO17722.1 - 0.2 12.1 1.1 2.6 8.5 0.0 2.8 2 1 1 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KDO17722.1 - 1.2 9.9 7.5 42 5.1 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat Metallophos PF00149.28 KDO17727.1 - 0.0049 17.4 0.0 0.0052 17.3 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KDO17730.1 - 0.16 12.5 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ESSS PF10183.9 KDO17731.1 - 0.0033 17.6 0.8 0.01 16.0 0.8 1.8 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TFA2_Winged_2 PF18121.1 KDO17731.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Acyl_transf_1 PF00698.21 KDO17732.1 - 7e-23 81.6 5.1 8.3e-23 81.4 5.1 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KDO17732.1 - 0.0032 17.2 0.6 0.03 14.1 0.6 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Histone PF00125.24 KDO17733.1 - 8.1e-53 178.3 1.3 9e-53 178.1 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KDO17733.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KDO17733.1 - 0.00028 21.5 0.3 0.00033 21.3 0.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO17733.1 - 0.00048 20.2 0.0 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KDO17733.1 - 0.0028 17.9 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO17733.1 - 0.12 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Defensin_RK-1 PF17860.1 KDO17736.1 - 0.38 11.2 3.4 15 6.1 0.1 2.9 2 1 0 2 2 2 0 RK-1-like defensin SDF PF00375.18 KDO17737.1 - 4.2e-53 180.8 28.7 5.3e-53 180.4 28.7 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5409 PF17421.2 KDO17737.1 - 0.036 14.8 0.4 0.14 12.9 0.4 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5409) MFS_1_like PF12832.7 KDO17738.1 - 6.3e-62 209.6 26.7 9.2e-62 209.1 26.7 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO17738.1 - 1.7e-22 79.9 67.0 3.2e-17 62.5 38.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO17738.1 - 8.5e-12 44.8 20.8 1.1e-11 44.4 20.8 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO17738.1 - 1e-08 34.4 17.7 1.4e-08 33.9 17.7 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 KDO17738.1 - 0.0085 14.5 21.2 0.014 13.8 21.2 1.3 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 KDO17739.1 - 3.5e-42 144.7 21.8 1.3e-38 132.9 13.9 2.0 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KDO17739.1 - 5.9e-12 45.2 27.4 7.1e-10 38.3 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO17739.1 - 3.7e-05 22.9 6.1 3.7e-05 22.9 6.1 1.5 1 1 1 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO17739.1 - 0.00032 19.6 0.9 0.00032 19.6 0.9 2.1 1 1 1 2 2 2 1 LacY proton/sugar symporter UNC-93 PF05978.16 KDO17739.1 - 0.015 15.0 3.6 0.061 13.0 3.6 2.1 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 OATP PF03137.20 KDO17739.1 - 0.58 8.4 8.3 0.32 9.2 1.9 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KDO17739.1 - 2.1 6.6 9.5 3.3 6.0 9.1 1.5 1 1 0 1 1 1 0 Transmembrane secretion effector MFS_1_like PF12832.7 KDO17740.1 - 3.4e-39 134.8 11.1 4.5e-33 114.6 6.6 2.0 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KDO17740.1 - 9.7e-14 51.1 14.6 3.4e-11 42.7 14.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO17740.1 - 5.1e-08 32.3 4.4 3.4e-06 26.3 1.2 2.0 1 1 1 2 2 2 2 Nucleoside H+ symporter PUCC PF03209.15 KDO17740.1 - 4.2e-05 22.7 3.8 6.8e-05 22.0 3.8 1.3 1 0 0 1 1 1 1 PUCC protein LacY_symp PF01306.19 KDO17740.1 - 0.0021 16.9 1.1 0.054 12.3 0.1 2.1 1 1 1 2 2 2 2 LacY proton/sugar symporter OATP PF03137.20 KDO17740.1 - 0.025 12.9 2.1 0.039 12.2 2.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KDO17740.1 - 0.47 8.8 5.4 0.33 9.3 2.9 1.7 1 1 1 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 KDO17741.1 - 3.5e-47 161.1 22.4 5.6e-31 107.8 9.7 2.3 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KDO17741.1 - 6.5e-10 38.5 37.2 3.3e-05 23.0 15.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO17741.1 - 7.3e-10 38.4 12.1 6.3e-05 22.1 2.8 2.1 1 1 1 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 KDO17741.1 - 0.0017 17.2 14.4 0.38 9.5 8.5 3.1 1 1 1 2 2 2 2 LacY proton/sugar symporter PDR_CDR PF06422.12 KDO17741.1 - 0.041 13.8 0.3 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 CDR ABC transporter Methyltransf_23 PF13489.6 KDO17742.1 - 4.7e-10 39.6 0.0 9.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO17742.1 - 1.9e-06 28.5 0.0 0.13 13.0 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KDO17742.1 - 5.3e-06 26.3 0.0 0.073 12.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KDO17742.1 - 7.7e-05 23.3 0.1 0.0092 16.6 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO17742.1 - 0.00021 21.9 0.0 0.11 13.2 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain DUF938 PF06080.12 KDO17742.1 - 0.0037 17.1 0.0 1.8 8.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF938) MTS PF05175.14 KDO17742.1 - 0.004 16.7 0.0 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KDO17742.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase DHHC PF01529.20 KDO17743.1 - 2.4e-16 60.1 3.1 2.4e-16 60.1 3.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase BT1 PF03092.16 KDO17743.1 - 5.1e-09 34.9 1.8 8.1e-09 34.2 1.8 1.2 1 0 0 1 1 1 1 BT1 family PUCC PF03209.15 KDO17743.1 - 0.00028 20.0 0.4 0.00064 18.8 0.4 1.6 1 0 0 1 1 1 1 PUCC protein DUF1533 PF07550.11 KDO17744.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) DUF2607 PF10795.9 KDO17744.1 - 0.39 10.9 14.3 2 8.6 7.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) Pkinase PF00069.25 KDO17745.1 - 6.6e-65 219.1 0.0 7.7e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17745.1 - 9.8e-20 70.9 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO17745.1 - 8.2e-07 29.2 0.0 3.4e-05 23.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO17745.1 - 0.0013 17.6 0.1 0.0047 15.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO17745.1 - 0.0039 16.6 0.4 0.0085 15.5 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO17745.1 - 0.014 15.0 0.2 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ALO PF04030.14 KDO17747.1 - 4.5e-22 79.1 0.0 1.2e-21 77.7 0.0 1.7 1 1 1 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KDO17747.1 - 3.1e-18 65.9 3.3 5.6e-18 65.0 3.3 1.5 1 0 0 1 1 1 1 FAD binding domain DHBP_synthase PF00926.19 KDO17749.1 - 1.7e-56 190.8 0.0 2.5e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 KDO17749.1 - 0.026 14.1 0.0 7 6.2 0.0 2.4 1 1 1 2 2 2 0 GTP cyclohydrolase II Abhydrolase_1 PF00561.20 KDO17750.1 - 3.4e-29 102.3 1.5 2.6e-26 92.8 0.7 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO17750.1 - 2.9e-16 59.4 0.0 6.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KDO17750.1 - 0.0083 15.4 0.1 0.15 11.3 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 SKN1 PF03935.15 KDO17752.1 - 4.9e-61 206.6 20.8 3.4e-26 91.7 1.7 5.1 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) DUF5454 PF17535.2 KDO17752.1 - 0.17 11.2 0.4 0.29 10.5 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5454) CwfJ_C_1 PF04677.15 KDO17759.1 - 4.4e-31 107.3 0.0 6.4e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KDO17759.1 - 9.4e-27 93.8 0.0 2.8e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Peptidase_S10 PF00450.22 KDO17762.1 - 4e-113 379.0 0.0 5.1e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KDO17763.1 - 4.9e-94 316.1 0.1 6.1e-94 315.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase dCMP_cyt_deam_1 PF00383.23 KDO17765.1 - 4e-16 58.7 1.1 5.2e-16 58.4 1.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KDO17765.1 - 4.1e-12 46.5 1.1 1.6e-09 38.1 0.9 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KDO17765.1 - 0.096 12.3 2.3 5.8 6.5 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PAN_4 PF14295.6 KDO17766.1 - 5.2e-19 67.9 24.3 8e-08 32.1 0.6 4.4 4 0 0 4 4 4 3 PAN domain PAN_2 PF08276.11 KDO17766.1 - 0.0056 16.8 21.6 0.97 9.6 3.2 3.7 3 0 0 3 3 3 3 PAN-like domain PAN_3 PF08277.12 KDO17766.1 - 2 8.3 20.7 0.88 9.4 1.9 3.8 4 0 0 4 4 4 0 PAN-like domain Transposase_21 PF02992.14 KDO17766.1 - 5.9 6.1 5.5 22 4.2 0.3 2.3 2 0 0 2 2 2 0 Transposase family tnp2 LodA_N PF17990.1 KDO17768.1 - 0.17 11.8 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal Crystall PF00030.19 KDO17769.1 - 0.00085 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Syncollin PF15138.6 KDO17769.1 - 0.0067 16.6 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 Syncollin Crystall_3 PF08964.10 KDO17769.1 - 0.053 13.7 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin BPL_LplA_LipB PF03099.19 KDO17770.1 - 6e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4495 PF14906.6 KDO17771.1 - 0.26 10.3 2.0 0.42 9.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) RGS_DHEX PF18148.1 KDO17771.1 - 9.3 6.4 10.2 0.72 10.0 2.4 2.4 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Sulfotransfer_2 PF03567.14 KDO17772.1 - 0.032 14.2 1.0 0.035 14.0 1.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Sel1 PF08238.12 KDO17773.1 - 1.3e-20 73.4 26.4 8.7e-05 23.1 0.2 7.9 7 1 0 7 7 7 5 Sel1 repeat TPPK_C PF12555.8 KDO17774.1 - 8.4 6.5 8.7 26 4.9 0.0 3.4 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Wound_ind PF08186.11 KDO17777.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 Wound-inducible basic protein family DUF4131 PF13567.6 KDO17779.1 - 0.49 10.0 11.8 0.31 10.7 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PAP2 PF01569.21 KDO17781.1 - 3.8e-23 81.8 7.9 9.3e-23 80.5 7.9 1.6 1 0 0 1 1 1 1 PAP2 superfamily DUF5426 PF17473.2 KDO17781.1 - 0.24 11.7 4.2 1 9.6 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5426) EamA PF00892.20 KDO17781.1 - 1.4 9.1 10.3 0.2 11.8 3.3 2.8 3 1 0 3 3 3 0 EamA-like transporter family PAP2_3 PF14378.6 KDO17781.1 - 4.3 7.0 19.4 1.4 8.6 3.6 2.7 2 1 1 3 3 3 0 PAP2 superfamily PhoD PF09423.10 KDO17782.1 - 2.6e-23 82.6 1.2 2.1e-21 76.3 1.2 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase Cupin_4 PF08007.12 KDO17785.1 - 4.8e-15 55.8 2.0 1.1e-14 54.7 1.4 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 KDO17785.1 - 2.8e-12 46.9 0.0 4.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KDO17785.1 - 0.00078 19.1 0.0 0.003 17.3 0.0 1.9 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 KDO17785.1 - 0.00091 19.6 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase CPSF73-100_C PF11718.8 KDO17785.1 - 0.59 9.6 2.2 1.7 8.1 2.3 1.7 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Ion_trans PF00520.31 KDO17786.1 - 2.8e-05 23.5 10.0 4.6e-05 22.8 10.0 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KDO17786.1 - 0.03 13.0 12.8 0.0063 15.2 8.1 1.9 1 1 1 2 2 2 0 Polycystin cation channel CrgA PF06781.12 KDO17786.1 - 5.5 7.1 5.3 25 5.0 2.8 2.6 2 0 0 2 2 2 0 Cell division protein CrgA Baculo_PEP_C PF04513.12 KDO17786.1 - 8.4 6.4 13.9 6.4 6.8 2.5 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 KDO17787.1 - 5.8e-15 55.7 0.3 9.4e-15 55.0 0.3 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17787.1 - 2.6e-14 51.9 0.1 1.2e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KDO17787.1 - 5e-13 48.9 0.4 1.9e-05 24.9 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO17787.1 - 5.7e-13 48.8 3.4 5.5e-09 36.1 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17787.1 - 2.1e-11 44.1 0.3 2.1e-08 34.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF5133 PF17196.4 KDO17787.1 - 0.096 12.9 0.6 0.48 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF5133) Ank_2 PF12796.7 KDO17788.1 - 1.5e-20 73.6 0.6 5.7e-13 49.3 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17788.1 - 9e-18 62.5 0.7 7.4e-07 29.0 0.1 4.9 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KDO17788.1 - 1e-17 64.2 1.2 9.3e-12 45.2 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO17788.1 - 1.2e-16 60.3 5.2 2.4e-09 37.2 0.3 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO17788.1 - 2e-15 56.7 3.3 2.8e-08 33.8 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) CDP-OH_P_transf PF01066.21 KDO17789.1 - 3.7e-13 50.0 0.6 3.7e-13 50.0 0.6 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4059 PF13268.6 KDO17789.1 - 0.047 14.1 0.2 0.13 12.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) LRR_4 PF12799.7 KDO17790.1 - 2.4e-06 27.8 2.2 0.13 12.7 0.0 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Coatomer_g_Cpla PF16381.5 KDO17790.1 - 0.015 15.4 2.6 11 6.2 0.1 3.2 1 1 3 4 4 4 0 Coatomer subunit gamma-1 C-terminal appendage platform LRR_6 PF13516.6 KDO17790.1 - 0.072 13.2 18.6 5.8 7.2 0.1 5.6 5 1 1 6 6 6 0 Leucine Rich repeat Tubulin_C PF03953.17 KDO17791.1 - 0.089 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin C-terminal domain Aida_C2 PF14186.6 KDO17795.1 - 3.3e-17 62.5 0.0 4e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Cytoskeletal adhesion Ion_trans PF00520.31 KDO17796.1 - 2.2e-05 23.8 15.0 2.2e-05 23.8 15.0 2.7 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO17796.1 - 2.7e-05 23.0 9.7 5.5e-05 22.0 9.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 KDO17797.1 - 1.5e-11 44.8 6.8 1.8e-06 28.4 0.8 3.4 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17797.1 - 3.8e-07 30.5 1.7 0.0094 16.5 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17797.1 - 0.00069 19.9 3.8 7.5 7.5 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KDO17797.1 - 0.0015 18.8 5.0 6.9 7.1 0.2 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO17797.1 - 0.0077 16.6 3.1 0.33 11.5 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat DUF2235 PF09994.9 KDO17798.1 - 4.7e-56 190.3 0.0 7.6e-56 189.6 0.0 1.3 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ADIP PF11559.8 KDO17799.1 - 0.014 15.5 4.8 0.014 15.5 4.8 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KDO17799.1 - 0.19 11.8 10.9 0.43 10.6 10.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LXG PF04740.12 KDO17799.1 - 0.28 10.9 5.7 0.58 9.8 5.7 1.6 1 0 0 1 1 1 0 LXG domain of WXG superfamily COG2 PF06148.11 KDO17799.1 - 0.29 11.2 2.0 1.3 9.1 1.6 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 KDO17799.1 - 0.4 10.7 14.4 0.24 11.5 10.4 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KDO17799.1 - 0.43 8.7 6.9 0.29 9.2 5.4 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA YabA PF06156.13 KDO17799.1 - 1.1 9.9 3.5 4.6 8.0 1.6 2.5 2 1 0 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KDO17799.1 - 3.1 8.1 7.9 0.45 10.8 2.6 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 KDO17799.1 - 7.4 5.4 13.5 0.71 8.7 9.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-B_dimeris PF09026.10 KDO17800.1 - 0.0035 17.7 7.0 0.0046 17.3 7.0 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Ctr PF04145.15 KDO17800.1 - 0.077 13.6 0.0 0.089 13.4 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family MFMR_assoc PF16596.5 KDO17800.1 - 0.11 13.0 3.2 0.14 12.6 3.2 1.1 1 0 0 1 1 1 0 Disordered region downstream of MFMR DNA_pol_phi PF04931.13 KDO17800.1 - 0.13 10.4 4.7 0.14 10.2 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KDO17800.1 - 1.9 8.2 12.3 2.5 7.8 12.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 KDO17800.1 - 2.4 6.1 9.7 2.7 6.0 9.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NOA36 PF06524.12 KDO17800.1 - 2.5 7.4 7.6 3.2 7.0 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein CS PF04969.16 KDO17801.1 - 2.7e-08 34.7 0.0 6.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 CS domain SAGA-Tad1 PF12767.7 KDO17801.1 - 0.012 15.4 1.7 0.014 15.2 1.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pinin_SDK_memA PF04696.13 KDO17801.1 - 0.22 11.6 13.1 0.41 10.7 13.1 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Pkinase_Tyr PF07714.17 KDO17802.1 - 1.2e-08 34.6 0.0 2.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 KDO17802.1 - 3.2e-05 23.8 5.1 0.12 12.4 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KDO17802.1 - 0.0031 17.5 0.6 0.066 13.2 0.0 3.2 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Pkinase PF00069.25 KDO17802.1 - 0.0052 16.2 0.1 0.0052 16.2 0.1 2.6 2 1 0 2 2 2 1 Protein kinase domain DUF1664 PF07889.12 KDO17802.1 - 2.9 8.0 11.3 0.19 11.8 2.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 KDO17802.1 - 2.9 7.5 25.4 0.36 10.5 0.9 3.8 2 2 1 3 3 3 0 SWI5-dependent HO expression protein 3 RRM_1 PF00076.22 KDO17803.1 - 2.7e-06 27.1 0.0 6.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO17803.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Na_Ca_ex PF01699.24 KDO17804.1 - 6.3e-12 45.7 7.7 8.7e-12 45.2 7.7 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein zf-A20 PF01754.16 KDO17805.1 - 3.7e-11 42.7 5.9 3.7e-11 42.7 5.9 2.1 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.16 KDO17805.1 - 2.9e-07 30.5 4.4 2.9e-07 30.5 4.4 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger Syndecan PF01034.20 KDO17806.1 - 8e-05 22.5 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 Syndecan domain VSP PF03302.13 KDO17806.1 - 0.00064 18.7 1.0 0.00072 18.5 1.0 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3283 PF11686.8 KDO17806.1 - 0.00091 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3283) DUF2681 PF10883.8 KDO17806.1 - 0.01 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Amnionless PF14828.6 KDO17806.1 - 0.03 13.2 0.0 0.031 13.1 0.0 1.0 1 0 0 1 1 1 0 Amnionless 7TM_GPCR_Srw PF10324.9 KDO17806.1 - 0.18 11.0 0.0 0.19 11.0 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw MtrF PF09472.10 KDO17806.1 - 0.22 10.9 3.4 0.33 10.4 3.4 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PTP_tm PF18861.1 KDO17806.1 - 0.66 9.9 4.2 0.94 9.4 3.7 1.3 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD99L2 PF12301.8 KDO17806.1 - 2.1 8.6 5.8 1.4 9.2 4.6 1.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 Ank_2 PF12796.7 KDO17807.1 - 2.4e-26 92.1 7.2 2.4e-08 34.4 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17807.1 - 1.5e-19 70.0 6.4 1.4e-06 28.7 0.0 5.2 2 2 3 6 6 6 5 Ankyrin repeats (many copies) PDZ_6 PF17820.1 KDO17807.1 - 4.1e-19 68.2 12.9 0.00019 21.2 0.6 6.1 5 1 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KDO17807.1 - 1.4e-13 51.0 0.0 0.0032 17.7 0.1 5.5 5 0 0 5 5 5 3 PDZ domain Ank_5 PF13857.6 KDO17807.1 - 6.2e-12 45.5 9.6 0.0034 17.7 0.1 6.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17807.1 - 1.4e-11 43.5 6.9 0.0069 16.8 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat PDZ PF00595.24 KDO17807.1 - 9.6e-09 35.5 0.0 3.2 8.2 0.0 5.3 5 0 0 5 5 5 3 PDZ domain Ank PF00023.30 KDO17807.1 - 1e-08 35.2 8.5 0.0026 18.1 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeat GRASP55_65 PF04495.14 KDO17807.1 - 5.6e-08 33.2 0.0 0.0037 17.6 0.0 3.6 3 0 0 3 3 3 2 GRASP55/65 PDZ-like domain Drc1-Sld2 PF11719.8 KDO17808.1 - 0.00086 19.0 13.0 0.014 15.0 0.4 2.9 2 1 1 3 3 3 2 DNA replication and checkpoint protein DUF728 PF05304.12 KDO17809.1 - 3.2 7.6 6.4 0.54 10.1 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF728) DUF658 PF04936.12 KDO17809.1 - 4.2 7.1 14.7 0.55 10.0 9.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF658) Pkinase PF00069.25 KDO17810.1 - 6.5e-49 166.7 0.0 8.3e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17810.1 - 3.9e-28 98.5 0.0 5.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17810.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO17810.1 - 0.00089 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO17810.1 - 0.0013 17.8 0.4 0.002 17.1 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO17810.1 - 0.0068 15.2 0.1 0.0077 15.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO17810.1 - 0.014 15.3 0.3 0.014 15.3 0.3 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 KDO17811.1 - 2e-52 175.7 13.5 2.7e-09 37.5 0.1 6.7 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17811.1 - 2.4e-46 155.5 4.7 2.8e-15 56.5 0.0 8.8 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO17811.1 - 2.5e-38 128.8 21.2 4.6e-08 33.2 0.0 11.9 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 KDO17811.1 - 1.3e-35 121.0 12.1 8.6e-12 45.1 0.0 8.9 6 3 5 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17811.1 - 1.9e-35 116.8 4.8 5.3e-05 23.3 0.0 13.0 13 0 0 13 13 13 6 Ankyrin repeat Pkinase PF00069.25 KDO17811.1 - 5.7e-33 114.4 0.0 1.2e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17811.1 - 3.6e-32 111.7 0.0 6.3e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO17811.1 - 0.011 15.1 0.0 0.04 13.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DZR PF12773.7 KDO17811.1 - 0.16 12.0 9.0 0.31 11.1 9.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon Shugoshin_N PF07558.11 KDO17812.1 - 3.4 7.6 7.2 1.2 9.1 0.1 4.0 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region LRR_6 PF13516.6 KDO17813.1 - 0.00077 19.3 7.4 0.11 12.6 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KDO17813.1 - 0.028 14.2 1.3 7.6 6.4 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat DUF1677 PF07911.13 KDO17814.1 - 0.0066 16.8 0.1 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1677) UPF0167 PF03691.14 KDO17814.1 - 0.069 12.9 0.3 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-FCS PF06467.14 KDO17814.1 - 0.93 9.5 4.0 1.8 8.6 4.0 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-FCS PF06467.14 KDO17815.1 - 0.32 11.0 3.6 0.2 11.7 1.7 1.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Tmemb_185A PF10269.9 KDO17816.1 - 3e-06 27.1 24.0 0.0031 17.3 1.1 2.9 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Tmemb_185A PF10269.9 KDO17817.1 - 3.9e-08 33.3 22.2 0.00085 19.1 2.9 3.2 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein HTH_Tnp_Tc5 PF03221.16 KDO17818.1 - 2.9e-09 36.8 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 KDO17818.1 - 7e-06 25.5 0.1 1.9e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KDO17818.1 - 0.00013 21.6 0.4 0.012 15.3 0.1 2.7 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KDO17818.1 - 0.00081 19.0 1.0 0.00081 19.0 1.0 2.2 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain UPF0122 PF04297.14 KDO17818.1 - 0.0026 18.0 0.0 0.0062 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_29 PF13551.6 KDO17818.1 - 0.0061 16.6 1.0 2.9 8.0 0.2 2.7 2 0 0 2 2 2 2 Winged helix-turn helix HTH_11 PF08279.12 KDO17818.1 - 0.027 14.4 0.1 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 KDO17818.1 - 0.027 14.6 7.3 0.98 9.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Tmemb_185A PF10269.9 KDO17819.1 - 4.1e-05 23.4 35.5 0.00092 19.0 1.5 3.8 1 1 1 3 3 3 3 Transmembrane Fragile-X-F protein Hanta_G1 PF01567.16 KDO17819.1 - 1.2 7.7 4.3 0.48 9.0 0.3 2.0 2 0 0 2 2 2 0 Hantavirus glycoprotein G1 PhoR PF11808.8 KDO17819.1 - 3 8.3 0.0 3 8.3 0.0 4.7 3 2 2 5 5 5 0 Phosphate regulon sensor protein PhoR Tmemb_185A PF10269.9 KDO17820.1 - 2.1e-07 30.9 24.0 0.0028 17.4 8.3 3.2 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein DUF3938 PF13074.6 KDO17820.1 - 0.14 12.4 2.5 0.21 11.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) RseC_MucC PF04246.12 KDO17820.1 - 1 9.3 5.0 0.57 10.1 1.9 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ank_2 PF12796.7 KDO17821.1 - 1.1e-24 86.8 4.5 1.6e-05 25.4 0.1 6.2 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17821.1 - 3.5e-15 56.1 14.1 1.5e-06 28.6 0.2 8.3 5 4 4 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO17821.1 - 2.1e-14 53.4 17.2 0.1 13.0 0.1 10.1 4 3 7 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17821.1 - 3.5e-09 36.2 16.1 11 7.0 0.0 11.7 13 1 1 14 14 14 2 Ankyrin repeat Ank PF00023.30 KDO17821.1 - 0.034 14.6 4.4 36 5.0 0.0 6.0 4 3 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 KDO17822.1 - 2.8e-17 63.1 1.5 3e-08 34.1 0.0 4.3 1 1 4 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17822.1 - 7.9e-14 50.4 5.9 0.04 14.5 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KDO17822.1 - 6.6e-13 48.6 1.9 3.8e-08 33.4 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO17822.1 - 1.7e-12 47.1 0.5 0.062 13.8 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KDO17822.1 - 1e-10 41.9 0.7 0.00092 19.7 0.0 5.1 4 2 2 6 6 6 2 Ankyrin repeats (many copies) UBA_2 PF08587.11 KDO17823.1 - 0.011 15.9 0.2 0.025 14.7 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Myb_DNA-bind_4 PF13837.6 KDO17823.1 - 0.014 15.8 0.1 0.014 15.8 0.1 2.8 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0556 PF10572.9 KDO17823.1 - 0.065 12.7 1.4 0.12 11.8 1.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 Pkinase PF00069.25 KDO17825.1 - 6.7e-34 117.5 0.0 8.7e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17825.1 - 4.4e-15 55.7 0.0 5.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO17825.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KDO17825.1 - 0.08 12.2 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Allene_ox_cyc PF06351.11 KDO17826.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Ribosomal_S7 PF00177.21 KDO17827.1 - 5.4e-29 100.8 1.1 7.1e-29 100.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDF PF00375.18 KDO17828.1 - 3e-71 240.5 45.9 2.2e-70 237.7 45.9 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO17829.1 - 5e-77 259.5 29.5 1.3e-76 258.1 29.5 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO17830.1 - 3.3e-69 233.8 39.5 1.5e-68 231.6 39.5 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Kinesin PF00225.23 KDO17832.1 - 1.8e-97 326.3 0.0 2.1e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO17832.1 - 1.5e-24 86.7 0.0 2.3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding HD_assoc PF13286.6 KDO17832.1 - 0.088 13.3 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 Phosphohydrolase-associated domain adh_short PF00106.25 KDO17833.1 - 3.6e-19 69.0 1.7 5.5e-19 68.4 1.7 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO17833.1 - 6.8e-14 52.0 1.9 1.6e-13 50.7 2.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO17833.1 - 2.8e-08 33.9 0.4 4e-08 33.4 0.4 1.1 1 0 0 1 1 1 1 KR domain DUF853 PF05872.12 KDO17833.1 - 0.025 13.2 0.9 0.029 13.0 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PLDc_2 PF13091.6 KDO17835.1 - 0.1 12.5 0.3 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 PLD-like domain PLDc_2 PF13091.6 KDO17836.1 - 2.2e-11 43.8 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 KDO17836.1 - 0.041 14.1 0.5 0.094 12.9 0.5 1.7 1 0 0 1 1 1 0 Phospholipase D Active site motif GDNF PF02351.16 KDO17836.1 - 0.095 13.7 0.6 0.16 13.0 0.6 1.3 1 0 0 1 1 1 0 GDNF/GAS1 domain DZR PF12773.7 KDO17837.1 - 0.0046 16.9 0.5 0.029 14.4 0.4 1.9 1 1 1 2 2 2 1 Double zinc ribbon zf_C2H2_10 PF18414.1 KDO17837.1 - 0.021 14.3 0.1 0.079 12.5 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc_ribbon_2 PF13240.6 KDO17837.1 - 0.059 13.1 2.3 7.3 6.5 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Ank_2 PF12796.7 KDO17838.1 - 7.5e-43 145.0 5.0 1.2e-15 57.9 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO17838.1 - 5.6e-34 115.1 14.7 3.7e-05 24.0 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KDO17838.1 - 4.1e-33 109.7 1.9 0.00019 21.6 0.0 7.6 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KDO17838.1 - 2.5e-29 101.0 10.4 2.8e-07 30.7 0.5 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO17838.1 - 2.6e-26 91.6 8.2 5.9e-08 33.1 0.1 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) MscS_porin PF12795.7 KDO17838.1 - 0.14 11.7 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain MFS_1 PF07690.16 KDO17839.1 - 0.0031 16.5 23.2 0.015 14.2 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 KDO17839.1 - 0.0035 16.7 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17839.1 - 0.0037 16.7 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4667 PF15700.5 KDO17840.1 - 0.0052 16.9 0.4 0.0088 16.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) AMP-binding PF00501.28 KDO17841.1 - 1.6e-33 116.0 0.0 2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HHH_3 PF12836.7 KDO17842.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 KDO17842.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 KDO17843.1 - 5e-06 26.7 0.1 6.3e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 KDO17844.1 - 0.00047 20.4 0.1 0.00065 19.9 0.1 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif YtxC PF08812.11 KDO17844.1 - 0.012 15.3 0.4 0.013 15.1 0.4 1.0 1 0 0 1 1 1 0 YtxC-like family DZR PF12773.7 KDO17845.1 - 1.3e-07 31.6 21.8 1.4e-05 25.0 5.4 2.9 1 1 0 2 2 2 2 Double zinc ribbon zf-RanBP PF00641.18 KDO17845.1 - 0.0098 15.2 2.6 0.0098 15.2 2.6 4.7 4 1 0 4 4 4 3 Zn-finger in Ran binding protein and others Importin_rep_4 PF18808.1 KDO17846.1 - 2.7e-10 40.4 0.2 1.3e-09 38.2 0.0 2.2 3 0 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 KDO17846.1 - 1.4e-07 31.8 1.5 0.09 13.2 0.0 5.8 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 KDO17846.1 - 2e-06 27.5 6.6 17 6.0 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Arm PF00514.23 KDO17846.1 - 0.062 13.4 0.8 97 3.2 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KDO17846.1 - 0.4 11.3 5.9 28 5.3 0.0 5.4 6 1 0 6 6 6 0 HEAT-like repeat Arm PF00514.23 KDO17847.1 - 6.2e-69 226.1 36.2 3.6e-07 30.0 0.0 19.0 19 0 0 19 19 19 17 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO17847.1 - 1.9e-11 44.2 24.0 0.0088 16.4 0.3 8.2 4 3 5 10 10 10 6 HEAT repeats HEAT PF02985.22 KDO17847.1 - 1.6e-08 34.1 23.6 0.89 10.0 0.0 10.7 10 0 0 10 10 10 3 HEAT repeat Atx10homo_assoc PF09759.9 KDO17847.1 - 3.8e-06 26.8 0.5 1.4 8.9 0.0 5.5 5 1 1 6 6 6 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KDO17847.1 - 0.00017 21.1 0.0 0.27 10.6 0.0 4.2 4 1 0 4 4 4 1 Armadillo-like HEAT_EZ PF13513.6 KDO17847.1 - 0.0009 19.7 37.2 0.17 12.4 0.1 9.7 6 2 4 11 11 11 4 HEAT-like repeat KAP PF05804.12 KDO17847.1 - 0.031 12.4 0.0 0.059 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) HEAT_PBS PF03130.16 KDO17848.1 - 0.11 13.3 0.7 32 5.6 0.1 3.7 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat Biotin_lipoyl PF00364.22 KDO17849.1 - 2.4e-15 56.1 0.1 3.9e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KDO17849.1 - 0.00013 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Peptidase_M14 PF00246.24 KDO17850.1 - 2.4e-21 76.8 0.0 2.7e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Phage_integrase PF00589.22 KDO17851.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Phage integrase family LRR_6 PF13516.6 KDO17852.1 - 1.2e-08 34.4 1.3 0.02 14.9 0.1 6.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 KDO17852.1 - 7e-06 26.3 0.1 0.0022 18.3 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO17852.1 - 0.0067 16.8 3.5 13 6.8 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KDO17852.1 - 0.011 15.5 1.7 0.14 12.0 0.0 3.6 4 1 0 4 4 4 0 Leucine rich repeat AA_permease_2 PF13520.6 KDO17853.1 - 3.9e-43 147.9 33.9 4.3e-43 147.7 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease SpoU_methylase PF00588.19 KDO17854.1 - 1.8e-18 67.1 0.0 2.2e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Dynamin_M PF01031.20 KDO17856.1 - 0.2 10.8 8.8 0.075 12.2 5.6 1.7 2 0 0 2 2 2 0 Dynamin central region P4Ha_N PF08336.11 KDO17856.1 - 1.6 8.8 5.9 7.7 6.5 0.0 3.3 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region zf-C4H2 PF10146.9 KDO17856.1 - 2.7 8.2 11.8 3.1 8.0 8.5 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein Med9 PF07544.13 KDO17856.1 - 3.4 7.8 8.2 2 8.6 1.5 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 cNMP_binding PF00027.29 KDO17857.1 - 3.6e-14 52.6 0.0 8e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RGS PF00615.19 KDO17857.1 - 4.3e-13 49.6 0.0 1.3e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain PCNA_C PF02747.15 KDO17857.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain BK_channel_a PF03493.18 KDO17859.1 - 7.6e-16 58.1 0.0 1.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit FYVE PF01363.21 KDO17860.1 - 1.2e-08 34.9 10.8 3.4e-08 33.5 10.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO17860.1 - 0.00019 21.6 3.7 0.00047 20.4 3.7 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger START PF01852.19 KDO17860.1 - 0.025 14.0 0.6 0.12 11.7 0.2 2.2 1 1 1 2 2 2 0 START domain PAPS_reduct PF01507.19 KDO17861.1 - 9e-26 91.0 0.0 1.2e-23 84.1 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FYVE PF01363.21 KDO17862.1 - 1.3e-10 41.3 16.0 3.1e-10 40.0 16.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO17862.1 - 0.0022 18.2 8.0 0.0046 17.2 8.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger START PF01852.19 KDO17862.1 - 0.019 14.4 0.1 0.069 12.6 0.1 1.8 2 0 0 2 2 2 0 START domain zf-RING_2 PF13639.6 KDO17862.1 - 1.6 9.1 19.1 0.58 10.5 15.4 2.3 2 0 0 2 2 2 0 Ring finger domain DUF4428 PF14471.6 KDO17862.1 - 2.9 7.9 8.3 7 6.7 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) FDF PF09532.10 KDO17863.1 - 1.5e-05 25.8 0.1 5.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 FDF domain WCCH PF03716.14 KDO17865.1 - 0.17 11.6 4.6 14 5.5 0.7 4.2 2 1 1 3 3 3 0 WCCH motif CCDC85 PF10226.9 KDO17867.1 - 0.0016 18.2 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 CCDC85 family FAM176 PF14851.6 KDO17867.1 - 0.0083 15.8 0.0 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 FAM176 family DivIC PF04977.15 KDO17867.1 - 0.015 15.0 0.2 0.015 15.0 0.2 2.5 2 1 0 2 2 2 0 Septum formation initiator TMEM237 PF15383.6 KDO17867.1 - 0.066 12.3 0.1 0.54 9.3 0.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 237 APG6_N PF17675.1 KDO17867.1 - 0.099 13.2 0.4 0.099 13.2 0.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TTC5_OB PF16669.5 KDO17867.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain DUF3357 PF11837.8 KDO17867.1 - 1.1 9.7 6.6 3 8.3 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) zf-met2 PF12907.7 KDO17868.1 - 0.67 10.1 3.7 0.78 9.9 0.9 2.2 2 0 0 2 2 2 0 Zinc-binding zf_C2H2_ZHX PF18387.1 KDO17869.1 - 7.4e-08 31.9 14.2 0.6 9.8 0.0 6.2 6 0 0 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KDO17869.1 - 1.1e-07 32.0 28.4 0.19 12.0 0.5 7.1 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KDO17869.1 - 2.1e-05 24.2 13.8 0.33 10.8 2.9 5.5 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KDO17869.1 - 6.3e-05 23.2 28.6 0.039 14.4 0.2 7.9 9 1 0 9 9 8 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 KDO17869.1 - 0.0013 19.0 9.1 0.23 11.8 0.1 4.8 4 2 1 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KDO17869.1 - 0.0063 16.9 27.7 0.66 10.6 1.5 6.9 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO17869.1 - 0.012 16.4 34.4 1.7 9.7 1.6 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KDO17869.1 - 0.013 15.3 18.1 0.54 10.1 0.1 5.1 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 KDO17869.1 - 0.021 14.8 8.2 0.37 10.8 0.0 3.9 3 2 1 4 4 4 0 CpXC protein OrsD PF12013.8 KDO17869.1 - 0.067 13.6 20.4 2.6 8.5 0.2 6.3 6 1 1 7 7 7 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF2719 PF10891.8 KDO17869.1 - 0.16 11.9 0.3 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2719) zf-C2H2_aberr PF17017.5 KDO17869.1 - 0.78 9.9 5.1 11 6.1 0.4 3.7 2 2 1 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 KDO17869.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DUF629 PF04780.12 KDO17869.1 - 4.5 5.7 4.2 28 3.0 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF629) PhnA_Zn_Ribbon PF08274.12 KDO17869.1 - 6.1 6.9 11.5 9.9 6.2 0.2 4.8 4 0 0 4 4 4 0 PhnA Zinc-Ribbon DUF4527 PF15030.6 KDO17870.1 - 0.2 11.1 1.8 0.22 10.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) HisG PF01634.18 KDO17871.1 - 1.4e-54 184.3 0.1 2e-54 183.9 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KDO17871.1 - 9.1e-26 89.8 0.0 1.7e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain DoxX PF07681.12 KDO17871.1 - 0.042 14.4 0.0 0.11 13.1 0.0 1.6 1 1 0 1 1 1 0 DoxX SBP_bac_3 PF00497.20 KDO17871.1 - 0.056 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DASH_Duo1 PF08651.10 KDO17872.1 - 0.00078 19.2 1.2 0.001 18.8 1.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 WXG100 PF06013.12 KDO17872.1 - 0.0039 17.4 0.9 0.0057 16.9 0.9 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Matrilin_ccoil PF10393.9 KDO17872.1 - 0.051 13.5 0.2 0.066 13.1 0.2 1.2 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2070 PF09843.9 KDO17873.1 - 5.3 5.2 10.1 6.2 5.0 10.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2530 PF10745.9 KDO17873.1 - 8.4 6.7 13.6 13 6.1 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4381 PF14316.6 KDO17873.1 - 9.1 6.5 8.5 0.49 10.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PUF PF00806.19 KDO17875.1 - 2.8e-05 23.5 0.0 1.1 9.0 0.0 4.6 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat Ribonuclease_3 PF00636.26 KDO17875.1 - 0.066 13.8 1.6 0.31 11.7 0.6 2.2 2 1 0 2 2 2 0 Ribonuclease III domain PUF PF00806.19 KDO17876.1 - 1.6e-05 24.3 0.0 0.087 12.6 0.0 3.3 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat Enterotoxin_b PF01376.18 KDO17876.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain HTH_32 PF13565.6 KDO17876.1 - 0.091 13.4 0.6 4.6 7.9 0.6 2.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF591 PF04569.14 KDO17876.1 - 0.18 11.9 0.1 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function Sds3 PF08598.11 KDO17877.1 - 3.6e-08 33.7 0.5 3.6e-08 33.7 0.5 1.6 2 0 0 2 2 2 1 Sds3-like Ribosomal_L32p PF01783.23 KDO17878.1 - 1.3e-10 41.4 5.4 1.8e-10 40.9 5.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Ank_5 PF13857.6 KDO17879.1 - 1.2e-23 82.8 8.8 1.7e-06 28.2 0.1 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO17879.1 - 1e-22 80.5 3.1 2.6e-07 31.1 0.2 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17879.1 - 4e-16 59.1 2.6 8.9e-07 29.4 0.1 5.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17879.1 - 2.1e-15 55.2 9.8 0.0066 16.9 0.1 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KDO17879.1 - 7e-10 38.9 17.8 0.0028 18.0 0.4 6.5 6 1 0 6 6 6 3 Ankyrin repeat TPR_8 PF13181.6 KDO17879.1 - 0.0017 18.4 2.3 0.099 12.9 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17879.1 - 0.036 14.9 0.2 0.036 14.9 0.2 7.1 7 1 1 8 8 6 0 Tetratricopeptide repeat RGS PF00615.19 KDO17879.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain TPR_1 PF00515.28 KDO17879.1 - 0.22 11.4 3.0 21 5.1 0.1 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO17879.1 - 0.42 10.3 9.9 7.6 6.3 0.5 4.3 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 KDO17879.1 - 0.63 10.3 9.6 0.65 10.2 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-B_box PF00643.24 KDO17879.1 - 0.7 10.1 15.8 2.3 8.4 15.8 2.0 1 0 0 1 1 1 0 B-box zinc finger TPR_7 PF13176.6 KDO17879.1 - 2.4 8.4 10.7 1.9 8.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Helicase_C PF00271.31 KDO17880.1 - 0.018 15.3 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain TPR_2 PF07719.17 KDO17881.1 - 0.0091 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO17881.1 - 0.054 13.3 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 KDO17882.1 - 2.5e-61 204.3 12.6 3.3e-12 46.8 0.0 6.7 3 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO17882.1 - 3.6e-55 183.6 9.5 1.7e-15 57.2 0.1 9.3 4 4 6 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KDO17882.1 - 3.9e-46 153.5 22.0 9.5e-06 25.8 0.1 12.7 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 KDO17882.1 - 6.6e-43 144.2 14.4 3.6e-10 39.9 0.0 10.3 5 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO17882.1 - 1.5e-42 138.7 5.7 0.00016 21.9 0.0 12.6 13 0 0 13 13 13 8 Ankyrin repeat Pkinase PF00069.25 KDO17882.1 - 1.5e-31 109.7 0.0 4e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17882.1 - 4.7e-31 108.0 0.0 1.3e-30 106.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase LIF_OSM PF01291.17 KDO17882.1 - 0.0022 18.2 0.1 0.0061 16.7 0.1 1.7 1 0 0 1 1 1 1 LIF / OSM family DZR PF12773.7 KDO17882.1 - 0.033 14.2 7.1 0.087 12.9 7.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 KDO17882.1 - 1.7 8.8 6.2 0.14 12.3 0.5 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 KAP PF05804.12 KDO17883.1 - 0.045 11.9 0.0 0.057 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) DUF4419 PF14388.6 KDO17886.1 - 8e-96 321.0 0.0 9.8e-96 320.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) ABC_tran PF00005.27 KDO17888.1 - 4.1e-28 98.6 0.0 6.5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO17888.1 - 6.5e-25 88.3 10.7 1.1e-24 87.5 10.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO17888.1 - 1.8e-06 27.6 0.2 0.0003 20.3 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO17888.1 - 2.1e-06 27.8 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KDO17888.1 - 0.00014 21.8 0.2 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO17888.1 - 0.00029 21.3 0.3 0.0016 18.9 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO17888.1 - 0.00034 20.9 0.1 0.0018 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KDO17888.1 - 0.00055 18.8 0.2 0.23 10.2 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Septin PF00735.18 KDO17888.1 - 0.004 16.5 0.0 0.0062 15.8 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_23 PF13476.6 KDO17888.1 - 0.0068 16.9 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KDO17888.1 - 0.0094 16.4 0.0 0.054 13.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KDO17888.1 - 0.012 15.3 0.0 0.04 13.7 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO17888.1 - 0.033 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Herpes_Helicase PF02689.14 KDO17888.1 - 0.056 11.4 0.0 0.08 10.9 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_25 PF13481.6 KDO17888.1 - 0.063 12.9 0.2 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KDO17888.1 - 0.063 13.5 0.2 0.26 11.5 0.1 2.2 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KDO17888.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KDO17888.1 - 0.11 12.5 0.3 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KDO17888.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 KDO17888.1 - 0.15 12.5 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pkinase_Tyr PF07714.17 KDO17892.1 - 5.6e-50 170.0 0.0 7.4e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17892.1 - 2.7e-47 161.3 0.0 4e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO17892.1 - 0.0012 17.8 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC_membrane PF00664.23 KDO17893.1 - 7.6e-21 75.0 9.3 7.6e-21 75.0 9.3 1.8 2 0 0 2 2 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO17893.1 - 2.6e-14 53.9 0.0 4.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KDO17893.1 - 0.014 15.8 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KDO17893.1 - 0.014 15.6 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KDO17893.1 - 0.035 13.8 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KDO17893.1 - 0.043 13.4 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KDO17893.1 - 0.058 13.1 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KDO17893.1 - 0.085 12.6 0.3 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KDO17893.1 - 0.095 12.4 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KDO17893.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KDO17893.1 - 0.24 11.9 2.4 0.17 12.4 0.3 1.7 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 KDO17896.1 - 1.5e-25 89.7 0.2 1.8e-20 73.0 0.0 3.3 1 1 2 3 3 3 3 SNF2 family N-terminal domain ResIII PF04851.15 KDO17896.1 - 0.0046 17.0 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KDO17896.1 - 0.085 13.2 0.0 0.36 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.31 KDO17897.1 - 0.00013 22.2 0.0 0.0002 21.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TPR_12 PF13424.6 KDO17898.1 - 1.2e-06 28.7 2.8 7.4e-05 23.0 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Acetyltransf_7 PF13508.7 KDO17899.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NifU_N PF01592.16 KDO17901.1 - 1.7e-55 186.6 0.3 2.1e-55 186.3 0.3 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Exo_endo_phos PF03372.23 KDO17903.1 - 2.5e-09 37.0 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dicty_REP PF05086.12 KDO17904.1 - 0.054 11.5 2.1 0.054 11.5 2.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KDO17904.1 - 0.063 13.2 1.3 0.077 13.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RabGAP-TBC PF00566.18 KDO17906.1 - 1e-32 113.6 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 KDO17906.1 - 0.00036 20.3 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO17906.1 - 0.0097 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Sina PF03145.16 KDO17907.1 - 0.0054 16.7 0.5 0.0087 16.0 0.5 1.3 1 0 0 1 1 1 1 Seven in absentia protein family Late_protein_L2 PF00513.18 KDO17907.1 - 0.034 13.2 1.9 0.027 13.5 1.0 1.2 1 1 0 1 1 1 0 Late Protein L2 TMEM43 PF07787.12 KDO17908.1 - 3.5e-37 128.1 0.0 4.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 Ank_2 PF12796.7 KDO17909.1 - 2.4e-08 34.4 0.1 1.2e-07 32.2 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO17909.1 - 6.5e-07 29.2 0.5 0.00028 21.1 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KDO17909.1 - 1.7e-06 28.2 0.9 0.0012 19.2 0.4 3.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KDO17909.1 - 6.4e-06 26.6 0.1 2.4e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) WW PF00397.26 KDO17909.1 - 1.8e-05 24.7 0.2 3.3e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 WW domain Ank_5 PF13857.6 KDO17909.1 - 0.017 15.5 0.1 0.059 13.7 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PKD_channel PF08016.12 KDO17910.1 - 2.2e-08 33.2 8.1 5.5e-08 31.9 8.1 1.7 1 0 0 1 1 1 1 Polycystin cation channel DUF4164 PF13747.6 KDO17910.1 - 0.0083 16.4 2.3 0.016 15.4 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Tmemb_cc2 PF10267.9 KDO17910.1 - 0.19 10.8 0.2 0.32 10.1 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Latarcin PF10279.9 KDO17910.1 - 0.26 11.7 0.6 0.71 10.3 0.6 1.7 1 0 0 1 1 1 0 Latarcin precursor DUF5453 PF17534.2 KDO17911.1 - 0.36 10.8 2.3 1 9.3 2.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Ion_trans PF00520.31 KDO17911.1 - 0.61 9.3 9.3 0.45 9.7 7.6 1.7 1 1 0 1 1 1 0 Ion transport protein IPTL-CTERM PF18203.1 KDO17912.1 - 0.0034 17.2 3.6 0.0051 16.7 0.6 2.5 2 0 0 2 2 2 1 IPTL-CTERM motif DUF4231 PF14015.6 KDO17912.1 - 0.018 15.5 1.8 0.021 15.3 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) TPR_8 PF13181.6 KDO17912.1 - 0.083 13.1 0.8 6.5 7.2 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ADSL_C PF10397.9 KDO17912.1 - 0.13 12.8 0.2 3.3 8.3 0.0 2.6 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus DUF3082 PF11282.8 KDO17912.1 - 0.16 12.2 3.0 4.9 7.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3082) TssN PF17555.2 KDO17912.1 - 0.33 10.3 1.5 0.44 9.9 1.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4131 PF13567.6 KDO17912.1 - 0.56 9.8 5.9 0.54 9.9 4.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PKD_channel PF08016.12 KDO17913.1 - 0.00026 19.8 4.3 0.00033 19.4 4.3 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KDO17913.1 - 0.00051 19.3 3.2 0.00062 19.1 3.2 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5476 PF17570.2 KDO17913.1 - 0.033 14.6 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5476) HrpB2 PF09487.10 KDO17914.1 - 0.058 13.8 1.9 0.075 13.5 1.9 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Cuticle_3 PF11018.8 KDO17917.1 - 0.02 15.1 51.0 0.5 10.5 26.1 2.9 1 1 2 3 3 3 0 Pupal cuticle protein C1 MyTH4 PF00784.17 KDO17918.1 - 0.01 16.3 2.7 2.5 8.7 0.1 3.3 2 1 1 3 3 3 0 MyTH4 domain DUF5024 PF16427.5 KDO17918.1 - 0.055 13.8 0.0 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) Fic_N PF13784.6 KDO17918.1 - 0.091 12.8 0.5 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Fic/DOC family N-terminal DUF2944 PF11161.8 KDO17922.1 - 0.015 15.2 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Pkinase_Tyr PF07714.17 KDO17924.1 - 1.1e-41 142.9 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17924.1 - 2.6e-33 115.5 0.0 3.5e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HALZ PF02183.18 KDO17924.1 - 0.14 12.4 0.2 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4558 PF15104.6 KDO17926.1 - 3.9e-17 62.1 4.0 5e-17 61.7 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) URO-D PF01208.17 KDO17927.1 - 8.4e-49 166.6 0.0 9.3e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TraH_2 PF06871.11 KDO17927.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 TraH_2 DUF1664 PF07889.12 KDO17928.1 - 0.0018 18.3 17.7 0.04 14.0 0.6 4.2 1 1 4 5 5 5 2 Protein of unknown function (DUF1664) FlxA PF14282.6 KDO17928.1 - 0.013 15.4 1.7 0.013 15.4 1.7 3.8 3 1 1 4 4 3 0 FlxA-like protein Tup_N PF08581.10 KDO17928.1 - 0.022 15.0 0.3 0.022 15.0 0.3 5.3 2 2 2 5 5 5 0 Tup N-terminal Flagellin_C PF00700.21 KDO17928.1 - 0.037 14.4 8.7 2 8.8 0.1 3.9 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region DUF948 PF06103.11 KDO17928.1 - 0.13 12.6 15.6 0.82 10.0 0.2 4.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DASH_Hsk3 PF08227.11 KDO17928.1 - 0.14 12.5 10.3 1.6 9.2 0.2 4.5 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like DUF3037 PF11236.8 KDO17928.1 - 0.15 12.5 11.9 0.037 14.5 2.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) YscO-like PF16789.5 KDO17928.1 - 0.22 11.6 22.5 1 9.4 15.3 3.2 2 1 1 3 3 3 0 YscO-like protein Acetyltransf_11 PF13720.6 KDO17928.1 - 0.59 10.6 2.2 1.9 9.0 0.3 2.8 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Noelin-1 PF12308.8 KDO17928.1 - 0.9 9.6 12.9 0.11 12.4 0.6 3.6 2 2 2 5 5 5 0 Neurogenesis glycoprotein Matrilin_ccoil PF10393.9 KDO17928.1 - 1.8 8.5 5.6 1.9 8.4 0.1 3.5 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin LOH1CR12 PF10158.9 KDO17928.1 - 3 7.9 8.3 0.22 11.6 1.7 2.3 2 1 1 3 3 3 0 Tumour suppressor protein Uso1_p115_C PF04871.13 KDO17928.1 - 9.8 6.6 28.4 2.5 8.5 4.0 3.6 2 2 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Acyl_transf_3 PF01757.22 KDO17930.1 - 2.8e-20 72.7 21.7 4.5e-20 72.0 21.7 1.3 1 0 0 1 1 1 1 Acyltransferase family Elicitin PF00964.17 KDO17931.1 - 0.003 17.6 2.9 0.003 17.6 2.9 4.1 4 1 0 4 4 4 2 Elicitin Nucleoside_tran PF01733.18 KDO17932.1 - 5.9e-17 62.0 12.2 6.2e-16 58.7 12.2 2.1 1 1 0 1 1 1 1 Nucleoside transporter Sugar_tr PF00083.24 KDO17932.1 - 0.00089 18.2 28.0 0.0016 17.4 17.5 2.6 1 1 1 3 3 3 3 Sugar (and other) transporter RbsD_FucU PF05025.13 KDO17933.1 - 7e-35 120.4 0.0 8.1e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family BT1 PF03092.16 KDO17934.1 - 5.9e-12 44.6 7.1 4.8e-10 38.3 0.4 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO17934.1 - 1e-05 24.7 9.3 8.4e-05 21.7 2.4 2.9 2 2 0 2 2 2 2 PUCC protein MerE PF05052.12 KDO17935.1 - 0.005 16.7 1.7 0.005 16.7 1.7 2.3 2 0 0 2 2 2 1 MerE protein PMP22_Claudin PF00822.20 KDO17935.1 - 0.0085 16.0 1.3 0.023 14.6 1.3 1.7 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family HupE_UreJ_2 PF13795.6 KDO17935.1 - 0.013 15.2 4.9 0.041 13.5 1.5 2.4 2 1 0 2 2 2 0 HupE / UreJ protein Secretin_N_2 PF07655.13 KDO17938.1 - 0.71 10.4 9.8 1.9 9.1 9.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Gemini_AL1_M PF08283.11 KDO17939.1 - 0.14 12.3 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Geminivirus rep protein central domain IBV_3A PF03617.13 KDO17940.1 - 0.14 12.2 0.2 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 IBV 3A protein DUF677 PF05055.12 KDO17945.1 - 7.3 5.4 7.2 7.9 5.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Aa_trans PF01490.18 KDO17947.1 - 3.4e-08 32.6 2.6 4.2e-08 32.3 2.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Yip1 PF04893.17 KDO17947.1 - 0.00094 18.9 1.1 0.0012 18.6 1.1 1.1 1 0 0 1 1 1 1 Yip1 domain ABC2_membrane PF01061.24 KDO17949.1 - 1.1e-31 109.9 14.3 1.2e-31 109.8 14.3 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KDO17949.1 - 0.88 8.6 19.7 1.7 7.7 19.7 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein FYVE PF01363.21 KDO17950.1 - 3.9e-15 55.7 12.1 5.9e-15 55.2 12.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 KDO17950.1 - 6.4e-05 23.3 0.1 0.00012 22.4 0.1 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KDO17950.1 - 0.00019 22.0 0.2 0.00044 20.9 0.2 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KDO17950.1 - 0.0013 19.1 0.1 0.0024 18.2 0.1 1.4 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO17950.1 - 0.0054 16.9 7.4 0.0098 16.1 7.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_5 PF14634.6 KDO17950.1 - 0.85 9.6 13.4 1.6 8.7 13.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 KDO17950.1 - 3 7.9 8.4 88 3.2 8.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon LCAT PF02450.15 KDO17952.1 - 1.6e-55 188.9 0.0 3.2e-55 187.9 0.0 1.3 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KDO17952.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KDO17952.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MFS_1 PF07690.16 KDO17954.1 - 2.2e-16 59.8 24.2 4e-16 58.9 24.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO17954.1 - 5.5e-05 22.2 12.3 0.00014 20.9 12.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO17955.1 - 1.3e-08 34.1 29.9 2.9e-07 29.8 12.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sex_peptide PF08138.11 KDO17955.1 - 4.4 7.5 5.6 1.2 9.3 1.4 2.3 2 0 0 2 2 2 0 Sex peptide (SP) family GSP_synth PF03738.14 KDO17956.1 - 1.5e-24 86.9 0.0 1.6e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CotH PF08757.11 KDO17958.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 CotH kinase protein Esterase PF00756.20 KDO17959.1 - 4.2e-57 193.7 0.0 4.8e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KDO17959.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KDO17959.1 - 0.0006 19.3 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KDO17959.1 - 0.023 14.4 0.1 0.04 13.6 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KDO17959.1 - 0.047 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KDO17959.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 KDO17959.1 - 0.13 11.8 0.0 0.54 9.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family RRM_1 PF00076.22 KDO17960.1 - 2.2e-41 139.5 0.0 1.6e-14 53.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO17960.1 - 4e-06 26.9 0.1 0.058 13.5 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO17960.1 - 0.018 15.0 0.0 0.2 11.7 0.0 2.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KDO17960.1 - 0.026 14.2 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_3 PF08777.11 KDO17960.1 - 0.071 13.2 0.0 0.37 10.9 0.0 2.1 3 0 0 3 3 3 0 RNA binding motif LolA PF03548.15 KDO17960.1 - 0.21 11.3 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA His_Phos_2 PF00328.22 KDO17961.1 - 8.8e-17 61.5 0.0 3.2e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KDO17963.1 - 2.2e-15 56.9 0.0 5.6e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Ricin_B_lectin PF00652.22 KDO17964.1 - 2.1e-14 53.8 2.4 3.1e-14 53.3 2.4 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO17964.1 - 7.7e-09 36.2 2.6 0.00036 21.2 0.4 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO17964.1 - 0.0011 18.6 0.8 0.0024 17.5 0.8 1.7 1 1 0 1 1 1 1 Cytolethal distending toxin A/C domain Trypsin_2 PF13365.6 KDO17965.1 - 1.1e-10 42.6 0.1 2.1e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO17965.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin Ricin_B_lectin PF00652.22 KDO17965.1 - 0.00035 20.8 0.9 0.003 17.8 0.1 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO17965.1 - 0.054 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Y_phosphatase2 PF03162.13 KDO17966.1 - 3.8e-55 186.0 0.0 4.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KDO17966.1 - 1.1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KDO17966.1 - 0.00062 19.6 0.0 0.00084 19.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO17966.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PB1 PF00564.24 KDO17967.1 - 1.7e-06 27.8 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PB1 domain UBA_4 PF14555.6 KDO17967.1 - 0.012 15.4 0.1 0.029 14.2 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain DUF3510 PF12022.8 KDO17967.1 - 0.053 13.9 0.3 0.59 10.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) AD PF09793.9 KDO17967.1 - 0.055 13.6 0.2 1.2 9.4 0.1 2.4 1 1 1 2 2 2 0 Anticodon-binding domain CUE PF02845.16 KDO17967.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 CUE domain Mob1_phocein PF03637.17 KDO17968.1 - 3e-09 37.1 2.2 2.9e-08 33.9 1.5 2.0 1 1 1 2 2 2 2 Mob1/phocein family DUF1635 PF07795.11 KDO17969.1 - 0.048 13.5 1.6 0.094 12.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) bMG10 PF17973.1 KDO17969.1 - 0.13 12.5 0.0 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain Toprim_C_rpt PF13368.6 KDO17970.1 - 0.0022 17.9 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase C-terminal repeat DUF3039 PF11238.8 KDO17970.1 - 0.027 14.2 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-HIT PF04438.16 KDO17970.1 - 0.029 14.2 0.7 0.042 13.7 0.1 1.6 2 0 0 2 2 2 0 HIT zinc finger WD40 PF00400.32 KDO17974.1 - 2.2e-33 113.7 17.2 2.2e-07 31.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KDO17974.1 - 6.9e-05 22.3 0.3 0.00027 20.4 0.1 2.0 2 1 1 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 KDO17974.1 - 0.00011 22.4 0.4 3.3 8.1 0.0 4.9 2 1 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KDO17974.1 - 0.15 11.1 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Peptidase_C70 PF12385.8 KDO17975.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 WD40 PF00400.32 KDO17975.1 - 0.055 14.4 0.1 1.4 10.0 0.1 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat F-box PF00646.33 KDO17975.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KDO17975.1 - 0.079 12.9 0.6 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 F-box-like DUF2431 PF10354.9 KDO17977.1 - 1.3e-06 28.8 0.0 1.9e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 KDO17977.1 - 0.0024 18.3 0.0 0.0044 17.4 0.0 1.3 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Cytomega_TRL10 PF06084.11 KDO17980.1 - 0.019 15.0 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein TMEM154 PF15102.6 KDO17980.1 - 0.021 14.7 0.4 0.038 13.9 0.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 KDO17980.1 - 0.061 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF5305 PF17231.2 KDO17980.1 - 0.17 11.3 0.2 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) CcmH PF03918.14 KDO17980.1 - 0.2 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein RIFIN PF02009.16 KDO17980.1 - 0.3 10.9 0.0 0.39 10.6 0.0 1.1 1 0 0 1 1 1 0 Rifin MGC-24 PF05283.11 KDO17980.1 - 0.37 11.2 6.1 0.68 10.4 6.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PRCC PF10253.9 KDO17984.1 - 2.7 8.7 6.2 3.6 8.3 6.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DNA_pol_phi PF04931.13 KDO17986.1 - 0.0009 17.5 11.6 0.00097 17.4 11.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KDO17986.1 - 0.026 14.3 9.6 0.027 14.2 9.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 KDO17986.1 - 0.072 12.2 10.2 0.078 12.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.8 KDO17986.1 - 0.52 9.4 5.2 0.48 9.5 5.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KDO17986.1 - 0.58 8.4 5.3 0.52 8.5 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KDO17986.1 - 0.72 9.1 9.6 0.81 9.0 9.6 1.1 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 KDO17986.1 - 0.73 8.8 5.6 0.72 8.8 5.6 1.1 1 0 0 1 1 1 0 Pes-10 Tom22 PF04281.13 KDO17986.1 - 1 9.1 7.0 1.4 8.7 7.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RRN3 PF05327.11 KDO17986.1 - 2.5 6.5 7.1 2.5 6.5 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 cNMP_binding PF00027.29 KDO17988.1 - 1.8e-29 101.6 0.2 3.4e-12 46.3 0.0 5.1 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain RGS PF00615.19 KDO17988.1 - 3.9e-06 27.1 0.0 1.7e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain MobB PF03205.14 KDO17988.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Motile_Sperm PF00635.26 KDO17989.1 - 8e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Erf4 PF10256.9 KDO17989.1 - 0.0019 18.3 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Rap1a PF18602.1 KDO17989.1 - 0.06 13.7 0.0 0.64 10.4 0.0 2.4 2 0 0 2 2 2 0 Rap1a immunity proteins F-box-like PF12937.7 KDO17990.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KDO17990.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box domain TPR_2 PF07719.17 KDO17991.1 - 1.2e-38 128.0 3.2 0.00013 21.8 0.0 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KDO17991.1 - 1.7e-34 116.3 8.1 1.3e-05 24.8 0.0 8.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KDO17991.1 - 4.5e-31 104.4 6.2 0.00088 19.3 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO17991.1 - 4.8e-25 87.0 3.5 1.9e-06 27.5 0.0 8.1 5 1 3 8 8 8 5 TPR repeat TPR_12 PF13424.6 KDO17991.1 - 1.5e-19 70.1 9.6 9.5e-05 22.6 0.1 6.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO17991.1 - 9.1e-19 67.8 0.5 0.00056 20.5 0.0 5.6 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO17991.1 - 2e-16 58.7 0.7 0.12 12.5 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO17991.1 - 6.8e-15 54.3 6.9 0.034 14.5 0.0 8.4 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO17991.1 - 2.4e-14 52.8 2.9 0.0079 16.9 0.0 8.0 5 3 5 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO17991.1 - 4.3e-13 49.2 0.1 0.00038 20.5 0.0 5.3 1 1 4 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO17991.1 - 9.9e-13 48.1 8.6 0.0022 18.2 0.5 5.7 2 2 5 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KDO17991.1 - 3.2e-11 43.6 0.7 0.19 12.2 0.1 6.3 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KDO17991.1 - 1.5e-09 37.9 4.8 14 6.6 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO17991.1 - 4.6e-08 32.7 5.3 3.1 7.8 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KDO17991.1 - 6.6e-05 22.3 0.2 1.8 7.7 0.0 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KDO17991.1 - 0.00025 20.1 1.4 0.11 11.4 0.1 3.0 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 KDO17991.1 - 0.002 18.1 6.7 10 6.2 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 KDO17991.1 - 0.0036 17.7 0.1 0.059 13.8 0.0 2.8 3 1 0 3 3 2 1 Bacterial transcriptional activator domain PknG_TPR PF16918.5 KDO17991.1 - 0.0057 15.4 0.1 2.4 6.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_MalT PF17874.1 KDO17991.1 - 0.0095 15.3 0.3 0.22 10.8 0.0 3.1 2 2 1 4 4 4 1 MalT-like TPR region Fis1_TPR_C PF14853.6 KDO17991.1 - 0.01 15.9 0.2 8.7 6.5 0.0 3.5 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat OMS28_porin PF03532.13 KDO17991.1 - 0.051 12.8 0.6 0.22 10.7 0.1 1.9 2 0 0 2 2 2 0 OMS28 porin Wzy_C_2 PF11846.8 KDO17991.1 - 0.054 13.4 0.1 3.8 7.4 0.0 3.4 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Clathrin PF00637.20 KDO17991.1 - 0.088 12.7 1.2 0.63 9.9 0.1 2.8 3 1 0 3 3 3 0 Region in Clathrin and VPS MIT PF04212.18 KDO17991.1 - 0.14 12.2 3.9 70 3.6 0.0 5.2 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TSC22 PF01166.18 KDO17992.1 - 3.8e-05 23.9 2.5 0.35 11.2 0.0 4.8 4 0 0 4 4 4 1 TSC-22/dip/bun family HALZ PF02183.18 KDO17992.1 - 0.00011 22.3 8.9 2.4 8.4 0.0 5.3 5 0 0 5 5 4 2 Homeobox associated leucine zipper ATG16 PF08614.11 KDO17992.1 - 0.0061 16.8 45.8 0.071 13.3 10.4 4.5 3 1 1 4 4 4 3 Autophagy protein 16 (ATG16) YabA PF06156.13 KDO17992.1 - 0.0067 17.0 11.4 2.7 8.7 0.1 4.9 2 1 0 4 4 4 1 Initiation control protein YabA Phage_GP20 PF06810.11 KDO17992.1 - 0.0069 16.2 15.7 0.0099 15.7 4.1 3.7 1 1 2 3 3 3 1 Phage minor structural protein GP20 GIT_CC PF16559.5 KDO17992.1 - 0.0086 15.9 1.3 0.057 13.3 0.1 3.1 3 0 0 3 3 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 KDO17992.1 - 0.013 15.9 0.5 0.013 15.9 0.5 6.2 5 2 1 6 6 6 0 Cell division protein ZapB CCDC74_C PF14917.6 KDO17992.1 - 0.016 15.7 0.1 0.13 12.8 0.0 2.6 2 0 0 2 2 1 0 Coiled coil protein 74, C terminal SHE3 PF17078.5 KDO17992.1 - 0.022 14.5 11.7 3.4 7.3 2.6 3.4 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 KDO17992.1 - 0.039 14.1 3.1 2.9 8.1 0.2 4.3 4 0 0 4 4 4 0 bZIP transcription factor Spc7 PF08317.11 KDO17992.1 - 0.041 12.8 27.8 0.019 13.9 7.4 3.6 2 1 1 4 4 4 0 Spc7 kinetochore protein DUF4878 PF12870.7 KDO17992.1 - 0.06 13.6 0.4 0.37 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Fez1 PF06818.15 KDO17992.1 - 0.077 13.4 26.8 0.038 14.5 8.6 2.9 2 1 1 3 3 3 0 Fez1 Gon7 PF08738.10 KDO17992.1 - 0.087 12.9 0.3 0.087 12.9 0.3 2.8 1 1 1 2 2 2 0 Gon7 family TMF_TATA_bd PF12325.8 KDO17992.1 - 0.19 11.9 0.1 0.19 11.9 0.1 5.0 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF5595 PF18077.1 KDO17992.1 - 0.27 11.3 4.5 6.9 6.8 0.1 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF5595) MPS2 PF17060.5 KDO17992.1 - 0.37 10.0 3.1 3.8 6.7 0.6 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 CENP-F_leu_zip PF10473.9 KDO17992.1 - 0.38 10.8 18.0 0.061 13.3 2.6 4.5 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 KDO17992.1 - 0.55 10.6 10.6 2.7 8.3 0.1 5.4 3 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 KDO17992.1 - 0.6 9.6 28.3 0.083 12.5 10.5 4.1 2 1 2 5 5 5 0 Intermediate filament protein SKA1 PF07160.12 KDO17992.1 - 0.85 9.4 9.5 0.96 9.2 0.6 3.3 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 FAM76 PF16046.5 KDO17992.1 - 1.2 8.5 6.9 1.4 8.2 4.6 2.3 2 0 0 2 2 2 0 FAM76 protein Prominin PF05478.11 KDO17992.1 - 2.8 5.8 4.2 3.1 5.6 2.0 2.0 1 1 1 2 2 2 0 Prominin Phage_fiber_2 PF03406.13 KDO17992.1 - 3.1 7.4 8.2 4.2 7.0 0.3 3.7 4 0 0 4 4 3 0 Phage tail fibre repeat APG6_N PF17675.1 KDO17992.1 - 8.5 6.9 38.7 4.9 7.7 6.4 5.4 2 1 4 6 6 5 0 Apg6 coiled-coil region DUF724 PF05266.14 KDO17992.1 - 9.4 6.0 15.6 0.36 10.6 1.0 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KDO17994.1 - 0.04 14.0 0.4 8 6.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 KDO17994.1 - 0.071 13.5 1.0 1.5 9.3 0.0 2.7 2 1 1 3 3 3 0 DASH complex subunit Dad2 Pkinase_Tyr PF07714.17 KDO17995.1 - 1.8e-34 119.2 0.0 4.8e-33 114.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17995.1 - 5.7e-33 114.4 0.0 9e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO17995.1 - 0.00069 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO17995.1 - 0.0027 17.0 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO17995.1 - 0.0073 15.3 0.0 0.0095 14.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KDO17995.1 - 0.013 15.2 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO17995.1 - 0.015 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO17995.1 - 0.057 12.2 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO17996.1 - 8e-24 84.3 0.0 1.9e-23 83.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17996.1 - 1.9e-18 66.8 0.0 3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO17997.1 - 8.5e-27 94.1 0.0 1.3e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO17997.1 - 1.9e-20 73.3 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO17997.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 KDO17998.1 - 8.8e-11 42.0 6.4 1.9e-10 40.9 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO17998.1 - 1e-07 31.7 7.7 2.1e-07 30.6 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO17998.1 - 2.8e-07 30.2 2.7 6.3e-07 29.0 2.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO17998.1 - 2.8e-07 30.7 4.1 7.6e-07 29.3 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO17998.1 - 3.5e-06 26.9 6.0 7.1e-06 25.9 6.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO17998.1 - 1.2e-05 25.0 6.0 2.7e-05 24.0 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO17998.1 - 3.9e-05 23.6 1.7 9.7e-05 22.3 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KDO17998.1 - 0.00012 21.6 5.2 0.00025 20.6 5.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KDO17998.1 - 0.00014 21.7 7.1 0.00025 20.9 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO17998.1 - 0.00025 20.8 7.0 0.00045 20.0 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO17998.1 - 0.0019 18.2 3.0 0.0053 16.8 3.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KDO17998.1 - 0.008 16.3 5.4 0.024 14.8 5.4 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KDO17998.1 - 0.051 13.6 2.8 0.14 12.2 2.8 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 KDO17998.1 - 0.22 11.9 2.6 0.59 10.5 2.6 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KDO17998.1 - 0.43 10.4 10.2 0.87 9.4 10.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KDO17998.1 - 0.74 10.0 8.4 1.8 8.8 8.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_10 PF16685.5 KDO17998.1 - 0.79 9.9 5.6 1.5 9.0 5.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 ABC_tran PF00005.27 KDO18001.1 - 1.1e-41 142.5 0.0 6e-28 98.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO18001.1 - 8.2e-24 84.7 21.5 1.1e-14 54.7 6.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO18001.1 - 2.3e-11 43.6 2.5 0.033 13.6 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO18001.1 - 1.3e-08 35.0 0.8 0.016 15.0 0.0 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO18001.1 - 5.6e-08 32.4 0.6 0.021 14.6 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO18001.1 - 3.5e-07 30.3 0.0 0.015 15.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO18001.1 - 2.4e-05 24.7 0.3 0.54 10.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KDO18001.1 - 7.7e-05 22.8 0.1 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 KDO18001.1 - 7.9e-05 23.1 0.1 0.53 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KDO18001.1 - 0.0001 22.9 0.1 0.34 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KDO18001.1 - 0.0001 21.7 0.3 0.49 9.7 0.2 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 KDO18001.1 - 0.0011 18.7 0.0 0.59 9.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO18001.1 - 0.0027 17.6 0.5 2.7 7.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KDO18001.1 - 0.0045 16.8 0.4 1.1 8.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KDO18001.1 - 0.0058 15.7 0.0 0.66 9.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.29 KDO18001.1 - 0.0061 16.3 2.9 0.034 13.9 1.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase cobW PF02492.19 KDO18001.1 - 0.0061 16.2 0.1 0.92 9.1 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KDO18001.1 - 0.0089 15.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KDO18001.1 - 0.037 13.8 0.0 5.4 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KDO18001.1 - 0.039 14.1 1.2 11 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 KDO18001.1 - 0.088 11.9 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KDO18001.1 - 0.09 12.5 0.3 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KDO18001.1 - 0.099 12.6 0.9 16 5.3 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 KDO18001.1 - 0.1 12.1 0.1 10 5.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KDO18001.1 - 0.11 11.4 0.0 10 4.9 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 KDO18001.1 - 0.13 12.8 0.0 6.2 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO18001.1 - 0.14 12.2 0.9 0.58 10.2 0.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KDO18001.1 - 0.17 12.1 0.0 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KDO18001.1 - 0.2 11.5 1.1 13 5.6 0.0 3.5 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 KDO18001.1 - 0.22 10.3 0.2 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Phage_holin_2_2 PF10746.9 KDO18001.1 - 4.8 6.9 6.4 1.4 8.7 2.5 2.1 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II PDT PF00800.18 KDO18005.1 - 8.6e-08 32.2 0.1 2.2e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 Prephenate dehydratase Aminotran_1_2 PF00155.21 KDO18005.1 - 0.0089 15.2 0.0 0.0089 15.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II ABATE PF07336.11 KDO18007.1 - 0.036 14.7 3.8 0.18 12.4 0.6 2.5 2 1 1 3 3 3 0 Putative stress-induced transcription regulator DSPc PF00782.20 KDO18008.1 - 3.6e-08 33.3 0.0 6.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO18008.1 - 3.3e-07 30.1 0.1 5.7e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KDO18008.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) KOG2701 PF09762.9 KDO18010.1 - 4.6e-16 59.6 0.0 7.2e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein (DUF2037) DUF2909 PF11137.8 KDO18011.1 - 0.0032 17.3 1.6 0.038 13.9 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2909) MARVEL PF01284.23 KDO18011.1 - 0.0067 16.5 0.2 0.0087 16.1 0.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain NrsF PF06532.11 KDO18011.1 - 0.016 14.9 7.1 0.018 14.8 6.8 1.3 1 1 0 1 1 1 0 Negative regulator of sigma F DUF5353 PF17304.2 KDO18011.1 - 0.13 12.1 0.9 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5353) Insulin_TMD PF17870.1 KDO18011.1 - 0.31 11.1 0.1 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Glyco_hydro_53 PF07745.13 KDO18013.1 - 0.0013 17.8 0.0 0.0026 16.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 Glyco_hydro_108 PF05838.12 KDO18013.1 - 0.13 12.8 0.1 0.26 11.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 108 MHYT PF03707.16 KDO18013.1 - 0.49 10.6 3.6 1.4 9.2 0.5 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat TMEM154 PF15102.6 KDO18013.1 - 8.3 6.3 12.3 4.6 7.1 0.4 2.3 1 1 1 2 2 2 0 TMEM154 protein family FYVE PF01363.21 KDO18014.1 - 2.7e-13 49.8 4.9 5.1e-13 49.0 4.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18014.1 - 0.0024 18.1 1.9 0.0057 16.9 1.9 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO18015.1 - 6.9e-12 45.3 11.7 1.6e-11 44.2 11.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18015.1 - 0.041 14.1 6.8 0.089 13.0 6.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 KDO18015.1 - 0.21 11.6 7.5 0.47 10.5 7.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger MgpC PF05220.12 KDO18017.1 - 0.028 13.8 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 MgpC protein precursor Spc7 PF08317.11 KDO18019.1 - 0.0038 16.1 2.4 0.007 15.3 2.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KDO18019.1 - 0.67 10.0 6.7 1.6 8.8 6.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 KDO18020.1 - 3.6e-58 197.0 0.0 1.7e-38 132.5 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18020.1 - 5.1e-25 88.2 0.0 1.9e-15 56.9 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KDO18020.1 - 2.6e-06 28.0 0.6 5.9e-06 26.9 0.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KDO18020.1 - 0.13 11.8 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KDO18020.1 - 0.4 9.9 2.3 1.5 8.0 0.0 2.3 2 1 1 3 3 3 0 Kinase-like p25-alpha PF05517.12 KDO18021.1 - 0.0049 17.0 0.0 0.4 10.8 0.0 3.3 3 0 0 3 3 3 1 p25-alpha EF-hand_like PF09279.11 KDO18021.1 - 0.026 15.0 0.3 3.1 8.3 0.1 3.0 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Exo_endo_phos PF03372.23 KDO18022.1 - 6.9e-09 35.6 0.0 7.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_1 PF00561.20 KDO18023.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO18023.1 - 0.00054 19.3 0.0 0.0093 15.3 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KDO18023.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CCDC85 PF10226.9 KDO18024.1 - 0.0022 17.7 1.6 0.0034 17.1 1.6 1.2 1 0 0 1 1 1 1 CCDC85 family Uso1_p115_C PF04871.13 KDO18024.1 - 1.3 9.4 5.3 2.4 8.5 5.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region F-box PF00646.33 KDO18026.1 - 0.00016 21.4 0.2 0.00061 19.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KDO18026.1 - 0.041 13.8 1.5 0.11 12.4 0.1 2.5 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.6 KDO18026.1 - 0.34 10.7 6.7 33 4.3 0.0 5.3 3 2 0 3 3 3 0 Leucine rich repeat Ank_2 PF12796.7 KDO18027.1 - 5e-12 46.2 0.3 1.3e-11 44.9 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18027.1 - 2.8e-11 43.7 0.2 8.8e-11 42.1 0.3 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18027.1 - 3.5e-11 43.1 3.1 2.8e-07 30.7 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KDO18027.1 - 4.8e-10 39.1 9.9 8.1e-10 38.4 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 KDO18027.1 - 5.9e-09 36.0 0.9 4.2e-05 23.8 0.2 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO18027.1 - 2.6e-08 33.5 0.3 0.0035 17.7 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 KDO18027.1 - 0.011 15.6 10.6 0.022 14.6 10.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UvrD_C_2 PF13538.6 KDO18028.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain C2 PF00168.30 KDO18028.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 C2 domain Methyltransf_4 PF02390.17 KDO18029.1 - 4.3e-24 84.9 0.0 5.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KDO18029.1 - 1e-05 25.2 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF2431 PF10354.9 KDO18029.1 - 0.026 14.8 0.0 0.067 13.5 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2431) HSF_DNA-bind PF00447.17 KDO18031.1 - 2.2e-23 82.7 0.7 3e-23 82.3 0.7 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4988 PF16378.5 KDO18031.1 - 0.042 13.5 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Chibby PF14645.6 KDO18031.1 - 0.044 14.2 0.1 0.062 13.7 0.1 1.3 1 0 0 1 1 1 0 Chibby family CCDC154 PF15450.6 KDO18031.1 - 0.16 10.5 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 RSN1_7TM PF02714.15 KDO18032.1 - 1.5e-31 109.8 19.1 2.6e-31 108.9 19.1 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KDO18032.1 - 4.3e-11 42.8 0.2 4.3e-11 42.8 0.2 4.1 4 2 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KDO18032.1 - 5.6e-07 30.0 0.0 3.8e-05 24.0 0.0 2.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CCSMST1 PF15013.6 KDO18032.1 - 0.091 12.9 0.1 8.2 6.7 0.0 3.1 2 0 0 2 2 2 0 CCSMST1 family DENN PF02141.21 KDO18033.1 - 2.1e-12 47.4 0.5 1.1e-11 45.1 0.1 2.4 2 1 1 3 3 3 1 DENN (AEX-3) domain RGS PF00615.19 KDO18033.1 - 8.4e-09 35.7 0.0 0.0017 18.6 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain LRR_6 PF13516.6 KDO18034.1 - 8.5e-12 44.1 8.2 0.017 15.1 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 KDO18034.1 - 0.00031 21.1 4.2 0.037 14.5 0.0 3.6 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO18034.1 - 0.39 10.5 6.7 20 5.0 0.0 4.1 4 1 1 5 5 5 0 Leucine rich repeat Goodbye PF17109.5 KDO18035.1 - 1.9 8.9 7.5 0.31 11.5 0.2 3.2 2 2 1 4 4 4 0 fungal STAND N-terminal Goodbye domain Sec3_C_2 PF15278.6 KDO18035.1 - 2.4 8.6 6.1 1.8 9.0 0.5 3.0 3 0 0 3 3 3 0 Sec3 exocyst complex subunit V_ATPase_I PF01496.19 KDO18035.1 - 7.5 4.3 18.4 19 3.0 18.4 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family KLRAQ PF10205.9 KDO18035.1 - 7.8 6.8 22.3 0.056 13.7 8.3 3.1 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein AMP-binding PF00501.28 KDO18036.1 - 1.9e-25 89.4 0.0 4e-25 88.3 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO18036.1 - 0.0025 18.8 0.6 0.011 16.7 0.7 2.0 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_Tnp_Tc5 PF03221.16 KDO18037.1 - 0.007 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Acyl-CoA_dh_2 PF08028.11 KDO18037.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain bPH_2 PF03703.14 KDO18038.1 - 0.062 13.5 0.0 0.27 11.4 0.0 1.9 1 1 1 2 2 2 0 Bacterial PH domain CCDC92 PF14916.6 KDO18039.1 - 0.00043 20.0 0.2 1.5 8.6 0.0 3.4 2 0 0 2 2 2 2 Coiled-coil domain of unknown function Filament PF00038.21 KDO18039.1 - 0.088 12.4 32.7 0.061 12.9 2.6 4.7 3 1 1 4 4 4 0 Intermediate filament protein FlaC_arch PF05377.11 KDO18039.1 - 0.09 13.2 3.2 14 6.2 0.0 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KDO18039.1 - 0.13 12.4 15.3 4.1 7.6 1.9 3.7 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Trimer_CC PF08954.11 KDO18039.1 - 0.21 11.2 3.4 8.7 6.0 0.0 4.0 3 1 1 4 4 4 0 Trimerisation motif TACC_C PF05010.14 KDO18039.1 - 0.24 11.2 23.7 0.37 10.5 2.4 3.4 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Syntaxin_2 PF14523.6 KDO18039.1 - 0.44 10.9 0.0 0.44 10.9 0.0 5.0 2 1 2 4 4 4 0 Syntaxin-like protein DUF4852 PF16144.5 KDO18039.1 - 0.6 10.3 3.9 0.23 11.6 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4852) PKcGMP_CC PF16808.5 KDO18039.1 - 2.3 8.2 8.9 5.8 6.9 0.1 4.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ThiF PF00899.21 KDO18041.1 - 3.8e-11 42.8 0.0 4.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KDO18041.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KDO18041.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA TfuA PF07812.12 KDO18041.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 TfuA-like protein MFS_1 PF07690.16 KDO18042.1 - 8.5e-29 100.6 20.0 9.7e-16 57.6 6.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KDO18042.1 - 0.00018 20.1 2.9 0.00018 20.1 2.9 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector DUF4246 PF14033.6 KDO18044.1 - 7.7e-31 107.7 0.0 1e-29 103.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) Ank_2 PF12796.7 KDO18044.1 - 1.2e-20 73.9 2.5 2.1e-10 41.0 0.3 5.6 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO18044.1 - 3e-19 68.8 1.6 2.5e-06 27.6 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO18044.1 - 1.5e-16 60.6 1.1 0.0018 18.8 0.1 5.8 3 2 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18044.1 - 6.7e-15 53.7 6.5 0.035 14.6 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KDO18044.1 - 2.8e-10 40.2 3.7 0.24 11.9 0.0 6.7 6 1 0 6 6 6 3 Ankyrin repeat PAN_4 PF14295.6 KDO18045.1 - 6.6e-07 29.1 1.2 0.00052 19.9 0.1 2.3 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 KDO18045.1 - 0.13 12.1 2.2 0.15 11.9 0.3 1.9 2 1 0 2 2 2 0 PAN-like domain KH_8 PF17903.1 KDO18047.1 - 6.3e-26 90.3 0.0 8.2e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Krr1 KH1 domain DUF608 PF04685.13 KDO18047.1 - 0.1 11.8 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Spc7 PF08317.11 KDO18048.1 - 0.0099 14.8 13.7 0.031 13.2 0.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein KASH_CCD PF14662.6 KDO18048.1 - 0.093 12.5 12.3 0.084 12.7 3.4 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Laps PF10169.9 KDO18048.1 - 0.15 12.6 6.6 0.74 10.4 4.2 2.2 1 1 1 2 2 2 0 Learning-associated protein AAA_28 PF13521.6 KDO18048.1 - 0.37 11.0 4.7 0.21 11.8 1.3 2.2 1 1 1 2 2 2 0 AAA domain DUF16 PF01519.16 KDO18048.1 - 0.78 10.2 4.3 3.1 8.3 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 ZapB PF06005.12 KDO18048.1 - 1.8 9.0 11.9 19 5.8 1.3 3.6 1 1 1 2 2 2 0 Cell division protein ZapB TBCC_N PF16752.5 KDO18048.1 - 2.2 8.7 9.2 0.48 10.9 1.1 2.9 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain BST2 PF16716.5 KDO18048.1 - 8.1 7.1 14.9 1.7 9.3 2.8 3.5 2 2 0 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 KDO18048.1 - 8.4 6.3 14.8 3.4 7.5 0.2 3.9 2 2 2 4 4 4 0 Septum formation initiator Enkurin PF13864.6 KDO18049.1 - 0.047 14.1 0.5 0.12 12.8 0.5 1.7 1 0 0 1 1 1 0 Calmodulin-binding FKBP_C PF00254.28 KDO18050.1 - 9e-36 122.1 0.0 1.1e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IF4E PF01652.18 KDO18051.1 - 3.2e-39 134.3 0.8 3.9e-39 134.0 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RtcR PF06956.11 KDO18051.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase YrhK PF14145.6 KDO18052.1 - 2.1e-26 91.5 27.9 9.4e-11 41.4 5.4 3.4 3 0 0 3 3 3 3 YrhK-like protein DUF4386 PF14329.6 KDO18052.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4386) TraQ PF09679.10 KDO18052.1 - 0.33 10.9 1.4 23 5.0 0.6 2.8 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF3668 PF12416.8 KDO18053.1 - 2.8e-15 56.7 0.1 7.1e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Cep120 protein DUF3439 PF11921.8 KDO18053.1 - 1.3 9.0 7.9 0.54 10.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PX PF00787.24 KDO18054.1 - 2.4e-08 33.9 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-RING_2 PF13639.6 KDO18055.1 - 4.1e-10 39.8 6.4 4.1e-10 39.8 6.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KDO18055.1 - 2.5e-06 27.7 7.4 5.5e-06 26.6 7.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO18055.1 - 1.7e-05 24.5 7.6 8.9e-05 22.3 7.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO18055.1 - 4.7e-05 23.3 4.5 0.00012 21.9 4.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO18055.1 - 8.1e-05 22.4 6.3 8.1e-05 22.4 6.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO18055.1 - 0.00013 21.8 5.2 0.00032 20.5 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO18055.1 - 0.00014 21.8 2.2 0.00014 21.8 2.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO18055.1 - 0.00028 20.6 1.1 0.00083 19.0 1.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 KDO18055.1 - 0.011 15.9 5.1 0.058 13.6 5.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PX PF00787.24 KDO18055.1 - 0.014 15.3 0.2 0.02 14.9 0.2 1.2 1 0 0 1 1 1 0 PX domain Prok-RING_4 PF14447.6 KDO18055.1 - 0.018 14.9 6.9 0.018 14.9 6.9 2.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO18055.1 - 0.076 12.6 10.2 0.28 10.8 10.2 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO18055.1 - 0.16 12.0 4.2 0.52 10.4 4.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KDO18055.1 - 0.32 11.2 7.4 0.6 10.3 6.8 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KDO18055.1 - 1.2 9.0 5.6 2.5 8.0 5.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KDO18056.1 - 6e-11 42.5 8.1 1e-10 41.7 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO18056.1 - 1.6e-08 34.7 4.6 1.4e-07 31.7 5.6 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO18056.1 - 2.6e-07 30.3 8.4 4.5e-07 29.6 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO18056.1 - 4.1e-06 26.4 5.2 8.2e-06 25.5 5.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO18056.1 - 4.9e-06 26.3 6.7 8.3e-06 25.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO18056.1 - 3.2e-05 23.8 8.1 6.6e-05 22.8 8.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO18056.1 - 0.00011 22.1 3.6 0.00018 21.4 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO18056.1 - 0.00017 21.6 2.4 0.0066 16.5 2.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO18056.1 - 0.00045 20.0 2.8 0.00086 19.1 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO18056.1 - 0.068 12.8 2.7 0.14 11.8 2.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KDO18056.1 - 0.088 13.0 4.2 0.27 11.4 4.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KDO18056.1 - 0.15 12.2 7.9 0.43 10.8 7.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 KDO18056.1 - 1.4 8.9 7.5 0.11 12.5 1.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Methyltransf_11 PF08241.12 KDO18057.1 - 7.8e-18 64.9 0.0 1.9e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO18057.1 - 1.7e-16 60.7 0.0 3.8e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18057.1 - 1.1e-13 51.7 0.0 1.9e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO18057.1 - 1.5e-13 50.8 0.0 1.9e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO18057.1 - 1.6e-10 41.0 0.0 1.9e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KDO18057.1 - 9.3e-07 28.7 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KDO18057.1 - 9.3e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KDO18057.1 - 0.00043 19.9 0.0 0.00082 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KDO18057.1 - 0.0036 17.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 KDO18057.1 - 0.0039 18.2 0.0 0.009 17.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 KDO18057.1 - 0.0096 16.0 0.0 0.014 15.5 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 KDO18057.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF938 PF06080.12 KDO18057.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.20 KDO18057.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KDO18057.1 - 0.042 12.9 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KDO18057.1 - 0.054 13.2 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) tRNA_U5-meth_tr PF05958.11 KDO18057.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Bin3 PF06859.12 KDO18057.1 - 0.17 12.5 0.0 0.46 11.2 0.0 1.6 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) PCMT PF01135.19 KDO18057.1 - 0.21 11.3 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NUDIX PF00293.28 KDO18058.1 - 4.8e-16 59.0 0.2 6e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Pur_ac_phosph_N PF16656.5 KDO18059.1 - 2.7e-16 59.9 1.7 5.3e-16 59.0 0.0 2.4 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KDO18059.1 - 0.00061 20.3 0.0 0.00089 19.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 KDO18059.1 - 0.07 13.2 0.1 0.37 10.9 0.0 2.0 1 1 1 2 2 2 0 Fn3-like domain from Purple Acid Phosphatase Glyoxalase PF00903.25 KDO18060.1 - 2.1e-05 24.7 0.2 0.00015 21.9 0.2 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3626 PF12294.8 KDO18060.1 - 0.024 13.7 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Glyoxalase_4 PF13669.6 KDO18060.1 - 0.048 13.9 0.0 0.075 13.3 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KDO18061.1 - 0.052 13.7 0.1 0.1 12.8 0.1 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Elicitin PF00964.17 KDO18063.1 - 0.0015 18.6 0.7 0.0015 18.6 0.7 1.6 1 1 1 2 2 2 1 Elicitin MGC-24 PF05283.11 KDO18063.1 - 0.018 15.5 4.8 0.018 15.5 4.8 1.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-C2H2 PF00096.26 KDO18064.1 - 0.0085 16.5 4.6 0.013 15.9 1.0 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 KDO18064.1 - 0.1 13.0 2.9 0.24 11.9 2.9 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KDO18064.1 - 0.11 12.9 0.2 0.23 11.9 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Herpes_glycop_D PF01537.17 KDO18064.1 - 0.11 12.7 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus glycoprotein D/GG/GX domain zf-C2H2_11 PF16622.5 KDO18064.1 - 0.19 11.5 0.8 0.37 10.6 0.8 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KDO18064.1 - 1.3 10.0 6.5 0.46 11.4 2.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.20 KDO18065.1 - 2.4e-20 73.0 0.2 3.1e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2 PF00096.26 KDO18065.1 - 7.7e-05 22.9 7.2 0.024 15.1 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO18065.1 - 0.00017 22.2 5.8 0.029 15.2 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KDO18065.1 - 0.056 13.8 2.0 12 6.3 0.0 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KDO18065.1 - 0.23 11.5 5.7 1.6 8.8 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KDO18065.1 - 0.5 10.3 7.7 2.1 8.4 1.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KDO18065.1 - 1.3 8.8 0.0 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Rubredoxin metal binding domain CpXC PF14353.6 KDO18065.1 - 2.6 8.1 5.9 8.6 6.4 3.7 2.9 2 2 1 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.10 KDO18065.1 - 4.2 7.6 7.9 32 4.7 0.1 3.4 2 1 1 3 3 3 0 Zinc ribbon domain Cytochrome_C7 PF14522.6 KDO18065.1 - 7.9 6.6 8.4 14 5.7 6.1 2.6 2 1 1 3 3 3 0 Cytochrome c7 and related cytochrome c Glyoxalase PF00903.25 KDO18066.1 - 6.7e-05 23.1 0.1 0.00018 21.7 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KDO18066.1 - 0.01 16.0 0.1 0.052 13.7 0.1 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KDO18066.1 - 0.03 14.6 0.2 0.23 11.7 0.2 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Caudo_TAP PF02413.17 KDO18067.1 - 0.036 14.2 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK OTU PF02338.19 KDO18068.1 - 2.3e-15 57.2 0.0 6.1e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease UIM PF02809.20 KDO18068.1 - 0.0071 16.2 25.3 0.75 9.9 2.5 5.1 4 0 0 4 4 4 4 Ubiquitin interaction motif Peptidase_C65 PF10275.9 KDO18068.1 - 0.071 12.5 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain DNTTIP1_dimer PF18192.1 KDO18068.1 - 0.18 12.2 0.1 3.3 8.1 0.0 2.6 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain CDP-OH_P_transf PF01066.21 KDO18070.1 - 5.1 8.0 7.2 0.97 10.3 0.1 3.3 3 2 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Raptor_N PF14538.6 KDO18071.1 - 6.5e-68 227.3 0.0 1.1e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KDO18071.1 - 1.8e-11 44.4 1.9 0.28 12.1 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO18071.1 - 1.1e-05 25.7 0.0 1 9.7 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KDO18071.1 - 0.0013 19.0 0.0 0.0044 17.4 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats Peptidase_C14 PF00656.22 KDO18071.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Caspase domain PQQ_3 PF13570.6 KDO18071.1 - 0.044 14.3 0.5 0.42 11.2 0.2 2.7 2 0 0 2 2 2 0 PQQ-like domain Cnd1 PF12717.7 KDO18071.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Ank_4 PF13637.6 KDO18072.1 - 2.3e-10 40.8 0.7 4.7e-05 23.9 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO18072.1 - 2.6e-08 34.0 0.3 6.6e-05 23.2 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO18072.1 - 1.3e-07 32.1 0.1 3.1e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO18072.1 - 1.7e-07 31.0 0.6 0.0002 21.6 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO18072.1 - 7.3e-06 26.2 1.7 7.5e-05 22.9 0.8 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RabGAP-TBC PF00566.18 KDO18074.1 - 1.2e-41 142.8 0.2 3e-41 141.4 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FYVE PF01363.21 KDO18074.1 - 6.4e-14 51.8 2.9 1.7e-13 50.5 2.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger ACBP PF00887.19 KDO18074.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Acyl CoA binding protein OPT PF03169.15 KDO18075.1 - 3.6e-98 329.8 52.5 4.3e-98 329.5 52.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nramp PF01566.18 KDO18077.1 - 0.018 14.0 0.2 0.029 13.3 0.2 1.3 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein DUF3879 PF12995.7 KDO18078.1 - 0.097 12.4 0.4 2.7 7.7 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) Ank_2 PF12796.7 KDO18079.1 - 1.6e-28 99.1 10.5 3.1e-06 27.7 0.1 6.4 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18079.1 - 1.3e-18 67.0 20.9 5.4e-05 23.7 0.1 8.8 5 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18079.1 - 6.5e-18 64.6 18.1 0.11 12.9 0.0 11.2 3 2 8 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18079.1 - 2.4e-12 45.9 16.7 6.9 7.6 0.0 12.1 9 2 4 13 13 13 3 Ankyrin repeat Ank PF00023.30 KDO18079.1 - 2.2e-09 37.3 10.0 0.69 10.5 0.0 9.0 5 3 1 6 6 6 2 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO18081.1 - 3.1e-42 144.6 0.0 4.1e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18081.1 - 4.6e-42 144.2 0.0 6.5e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO18081.1 - 0.00018 21.0 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 KDO18081.1 - 0.00035 20.5 7.9 0.0022 18.0 8.0 2.1 1 1 0 1 1 1 1 Double zinc ribbon APH PF01636.23 KDO18081.1 - 0.0035 17.3 0.0 0.0068 16.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family zinc_ribbon_2 PF13240.6 KDO18081.1 - 0.0036 17.0 6.4 0.21 11.3 0.3 3.0 3 0 0 3 3 3 2 zinc-ribbon domain Haspin_kinase PF12330.8 KDO18081.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KDO18081.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Fer4_13 PF13370.6 KDO18081.1 - 0.035 14.7 0.3 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I zf-ribbon_3 PF13248.6 KDO18081.1 - 0.071 12.5 8.7 1.4 8.4 0.1 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Stc1 PF12898.7 KDO18081.1 - 0.082 13.5 8.3 1.9 9.1 0.7 2.3 1 1 1 2 2 2 0 Stc1 domain TF_Zn_Ribbon PF08271.12 KDO18081.1 - 0.15 11.6 7.3 0.17 11.4 0.7 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 KDO18081.1 - 0.27 12.0 5.8 0.92 10.3 5.8 1.8 1 1 0 1 1 1 0 zinc-ribbon family zf_UBZ PF18439.1 KDO18081.1 - 1.3 8.6 4.1 7.6 6.2 0.1 3.0 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KDO18081.1 - 1.8 8.7 5.9 2 8.5 0.3 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ank_2 PF12796.7 KDO18082.1 - 7e-59 196.4 40.1 2.3e-12 47.3 2.9 8.2 4 1 4 8 8 8 6 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO18082.1 - 2.2e-45 155.1 0.0 3.3e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18082.1 - 5.2e-44 150.5 0.0 8.2e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO18082.1 - 1.2e-34 118.3 29.4 2.7e-07 31.0 0.0 9.6 7 2 2 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18082.1 - 1.3e-33 111.2 33.7 0.11 13.2 0.1 15.1 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.6 KDO18082.1 - 2.4e-27 94.6 48.4 4.5e-05 23.6 2.3 12.4 5 3 8 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 KDO18082.1 - 2.5e-27 94.1 65.4 0.0036 17.7 0.1 14.1 11 3 3 14 14 14 10 Ankyrin repeat Kdo PF06293.14 KDO18082.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4913 PF16259.5 KDO18082.1 - 0.11 12.5 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) DZR PF12773.7 KDO18082.1 - 0.42 10.7 9.0 0.84 9.7 9.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon SR-25 PF10500.9 KDO18082.1 - 0.97 9.0 3.8 1.7 8.2 3.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Init_tRNA_PT PF04179.12 KDO18082.1 - 1.3 9.4 8.6 5 7.5 0.1 4.5 4 1 1 5 5 5 0 Rit1 DUSP-like domain DUF2390 PF09523.10 KDO18082.1 - 2.2 8.6 7.5 10 6.5 0.1 4.5 2 2 3 5 5 5 0 Protein of unknown function (DUF2390) MFS_1 PF07690.16 KDO18083.1 - 5.1e-13 48.7 76.1 4e-09 35.9 40.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KDO18083.1 - 5.6e-06 26.0 8.0 0.0068 15.9 0.5 2.9 1 1 2 3 3 3 2 Nodulin-like DUF1065 PF06358.11 KDO18083.1 - 0.064 13.2 1.1 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) Pkinase PF00069.25 KDO18084.1 - 2.7e-44 151.5 0.0 3.8e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18084.1 - 2.9e-43 148.0 0.0 4.2e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KDO18084.1 - 3.4e-23 82.0 4.0 1e-11 45.2 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18084.1 - 1.3e-19 70.2 3.1 3.6e-08 33.8 0.1 4.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18084.1 - 9.1e-17 59.5 2.7 0.05 14.2 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KDO18084.1 - 1.3e-14 54.0 7.1 6.1e-05 23.2 0.2 5.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO18084.1 - 2.8e-13 49.7 11.9 0.019 15.4 0.2 6.7 7 0 0 7 7 7 4 Ankyrin repeat Kdo PF06293.14 KDO18084.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 KDO18084.1 - 0.71 9.9 7.9 1.5 8.9 7.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 KDO18084.1 - 3.6 7.0 10.5 0.16 11.3 3.9 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ABC_tran PF00005.27 KDO18085.1 - 3.9e-21 76.0 0.0 5.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KDO18085.1 - 0.00071 20.0 0.2 0.0018 18.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO18085.1 - 0.0056 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO18085.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KDO18085.1 - 0.044 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain IstB_IS21 PF01695.17 KDO18085.1 - 0.05 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 KDO18085.1 - 0.063 12.4 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KDO18085.1 - 0.069 13.3 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KDO18085.1 - 0.075 13.1 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SMC_N PF02463.19 KDO18085.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO18085.1 - 0.15 11.9 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KDO18085.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO18085.1 - 0.2 11.7 0.1 0.42 10.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Asparaginase_2 PF01112.18 KDO18086.1 - 2.1e-13 50.0 4.2 2.3e-13 49.9 4.2 1.0 1 0 0 1 1 1 1 Asparaginase FR47 PF08445.10 KDO18087.1 - 5.3e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KDO18087.1 - 2.2e-05 24.7 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO18087.1 - 5.2e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO18087.1 - 0.00015 21.7 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO18087.1 - 0.023 15.4 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GST_C_3 PF14497.6 KDO18088.1 - 5.5e-14 52.2 0.1 8.8e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO18088.1 - 4.6e-05 23.7 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO18088.1 - 0.00088 19.4 0.0 0.0019 18.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO18088.1 - 0.00095 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PWI PF01480.17 KDO18088.1 - 0.081 13.2 0.1 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 PWI domain GST_C_3 PF14497.6 KDO18089.1 - 1.9e-13 50.5 0.0 3.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO18089.1 - 6.8e-07 29.2 1.2 4.2e-06 26.7 1.2 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO18089.1 - 1.6e-05 25.1 0.0 2.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO18089.1 - 0.00028 21.1 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lant_dehydr_C PF14028.6 KDO18090.1 - 0.015 14.8 0.9 0.029 13.9 0.9 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF769 PF05590.11 KDO18090.1 - 0.23 10.9 0.1 0.33 10.4 0.1 1.2 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) PTPlike_phytase PF14566.6 KDO18091.1 - 6.2e-65 218.1 0.5 4.9e-44 150.2 0.0 2.4 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase PF00102.27 KDO18091.1 - 0.00028 20.5 0.1 0.31 10.6 0.0 2.5 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 KDO18091.1 - 0.00034 20.4 0.0 0.27 11.0 0.0 2.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO18091.1 - 0.043 13.8 0.2 3.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Tyrosine phosphatase family DUF4248 PF14053.6 KDO18091.1 - 0.13 12.3 0.1 61 3.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) SlyX PF04102.12 KDO18092.1 - 0.013 16.1 1.0 0.021 15.4 1.0 1.3 1 0 0 1 1 1 0 SlyX DUF2654 PF10849.8 KDO18092.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) DUF2730 PF10805.8 KDO18092.1 - 0.11 12.5 0.2 0.28 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Glyco_hydro_3 PF00933.21 KDO18093.1 - 3.6e-22 79.1 0.0 5.5e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KDO18093.1 - 3.3e-21 76.2 0.0 4.9e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KDO18093.1 - 2e-07 31.0 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Vps54 PF07928.12 KDO18094.1 - 2.2e-44 151.2 2.6 1.2e-43 148.7 2.6 2.4 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KDO18094.1 - 3e-18 66.1 11.3 2.6e-17 63.0 0.6 3.1 3 0 0 3 3 3 2 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 KDO18094.1 - 0.0035 17.4 3.9 0.0035 17.4 3.9 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF334 PF03904.13 KDO18094.1 - 0.024 14.2 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sec8_exocyst PF04048.14 KDO18094.1 - 0.084 12.8 6.8 0.073 13.0 3.6 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TrbC PF04956.13 KDO18094.1 - 0.13 12.5 0.9 0.55 10.5 0.9 2.1 1 0 0 1 1 1 0 TrbC/VIRB2 family Flagellin_N PF00669.20 KDO18094.1 - 0.33 11.1 3.2 28 4.8 0.1 3.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region COG5 PF10392.9 KDO18094.1 - 1 9.5 12.9 0.61 10.3 4.4 4.0 4 0 0 4 4 4 0 Golgi transport complex subunit 5 SpoIIIAH PF12685.7 KDO18094.1 - 3.6 7.4 10.5 0.7 9.7 0.7 2.8 2 1 0 2 2 2 0 SpoIIIAH-like protein HECT PF00632.25 KDO18096.1 - 1.4e-82 277.6 0.0 1.8e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO18096.1 - 0.00042 19.6 0.8 0.00082 18.6 0.8 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KDO18096.1 - 0.04 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Glyco_hydro_20 PF00728.22 KDO18099.1 - 2.4e-93 313.4 0.0 2.9e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KDO18099.1 - 5.6e-12 46.5 0.1 4.5e-11 43.6 0.1 2.2 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KDO18099.1 - 1.1e-07 32.7 0.2 6.5e-07 30.2 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 RecO_N_2 PF13114.6 KDO18099.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 RecO N terminal AP_endonuc_2 PF01261.24 KDO18099.1 - 0.14 11.6 0.0 7.4 5.9 0.0 2.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel ERp29 PF07749.12 KDO18100.1 - 1.4e-17 64.4 0.1 1.6e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain FA_desaturase_2 PF03405.14 KDO18100.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase HECT PF00632.25 KDO18101.1 - 1.6e-75 254.4 0.0 2.5e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO18101.1 - 0.012 14.9 1.8 0.023 14.0 1.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SNN_transmemb PF09049.10 KDO18102.1 - 4.1 7.4 9.7 0.21 11.5 3.1 2.3 2 0 0 2 2 2 0 Stannin transmembrane DUF3392 PF11872.8 KDO18102.1 - 5.2 7.4 8.9 21 5.4 1.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3392) HECT PF00632.25 KDO18103.1 - 5.3e-73 246.2 0.0 7.3e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps36-NZF-N PF16988.5 KDO18103.1 - 0.28 10.6 2.9 1.9 8.0 2.9 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TMEM171 PF15471.6 KDO18105.1 - 0.041 12.9 2.2 0.046 12.7 2.2 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Glyco_transf_22 PF03901.17 KDO18106.1 - 2.9e-47 161.8 21.5 3.4e-47 161.6 21.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Abhydrolase_1 PF00561.20 KDO18107.1 - 1.1e-10 41.6 0.0 5.3e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO18107.1 - 0.0011 18.4 0.1 0.018 14.3 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO18107.1 - 0.0064 16.6 0.0 0.051 13.7 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein CrgA PF06781.12 KDO18107.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA Aldedh PF00171.22 KDO18109.1 - 4.1e-135 450.9 0.2 4.7e-135 450.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 KDO18109.1 - 0.04 13.9 0.4 0.09 12.7 0.4 1.5 1 0 0 1 1 1 0 Ribosome recycling factor LuxC PF05893.14 KDO18109.1 - 0.052 12.6 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) OmdA PF13376.6 KDO18109.1 - 0.097 12.7 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Ank_5 PF13857.6 KDO18110.1 - 2.1e-06 27.9 0.0 0.14 12.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO18110.1 - 3.5e-06 27.5 0.0 1.3 9.7 0.0 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO18110.1 - 0.00036 20.8 0.4 11 7.0 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Sugar_tr PF00083.24 KDO18111.1 - 1.2e-94 317.7 20.0 1.5e-94 317.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO18111.1 - 4.8e-33 114.5 25.9 3.1e-22 79.0 9.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO18111.1 - 2.7e-07 29.4 1.9 2.7e-07 29.4 1.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_1 PF00583.25 KDO18113.1 - 3.8e-05 23.9 0.0 6.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO18113.1 - 0.00018 21.8 0.0 0.00035 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO18113.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KDO18113.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyl_transf_3 PF01757.22 KDO18115.1 - 8.5e-09 34.9 19.1 3.9e-08 32.8 19.1 1.9 1 1 0 1 1 1 1 Acyltransferase family Rad1 PF02144.16 KDO18116.1 - 8.8e-27 93.8 2.9 1.1e-26 93.5 2.9 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Waikav_capsid_1 PF12264.8 KDO18116.1 - 0.045 13.3 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Retrotran_gag_2 PF14223.6 KDO18118.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-ribbon_3 PF13248.6 KDO18118.1 - 0.57 9.7 1.9 1.4 8.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain LRV PF01816.17 KDO18121.1 - 1.4 9.4 12.9 0.94 10.0 1.1 4.1 3 0 0 3 3 3 0 Leucine rich repeat variant BT1 PF03092.16 KDO18123.1 - 9.4e-17 60.4 13.7 7.7e-15 54.1 0.9 2.2 2 0 0 2 2 2 2 BT1 family BT1 PF03092.16 KDO18124.1 - 1.8e-15 56.2 13.6 5.5e-14 51.3 2.2 2.3 2 0 0 2 2 2 2 BT1 family Otopetrin PF03189.13 KDO18124.1 - 0.013 14.4 3.3 0.025 13.4 2.4 1.8 2 0 0 2 2 2 0 Otopetrin Peptidase_C2 PF00648.21 KDO18126.1 - 4.6e-53 180.2 0.1 1.9e-52 178.2 0.1 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease IL32 PF15225.6 KDO18128.1 - 0.097 13.0 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Interleukin 32 Zmiz1_N PF18028.1 KDO18128.1 - 0.13 12.5 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain HlyE PF06109.13 KDO18128.1 - 0.21 10.9 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) zf-H2C2_2 PF13465.6 KDO18129.1 - 0.13 12.8 0.7 0.39 11.2 0.7 1.8 1 1 0 1 1 1 0 Zinc-finger double domain Thg1 PF04446.12 KDO18130.1 - 2.1e-50 169.9 0.0 3.4e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KDO18130.1 - 1e-36 125.8 0.3 1.5e-36 125.2 0.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain DUF1912 PF08930.10 KDO18130.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) GDPD PF03009.17 KDO18131.1 - 6.2e-15 55.6 0.0 1.3e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DNase-RNase PF02577.14 KDO18133.1 - 0.05 13.3 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Bifunctional nuclease Vpu PF00558.19 KDO18134.1 - 0.045 13.5 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 Vpu protein LRR_6 PF13516.6 KDO18135.1 - 8.1e-05 22.4 2.9 11 6.3 0.0 6.0 7 0 0 7 7 7 3 Leucine Rich repeat DUF433 PF04255.14 KDO18135.1 - 0.12 12.3 0.1 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Methyltransf_18 PF12847.7 KDO18138.1 - 0.0065 16.4 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_M14 PF00246.24 KDO18139.1 - 1.7e-18 67.4 0.8 9.1e-18 65.1 0.8 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase EphA2_TM PF14575.6 KDO18139.1 - 0.058 14.3 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DEC-1_N PF04625.13 KDO18140.1 - 0.22 10.5 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_trans_1_4 PF13692.6 KDO18141.1 - 8.2e-07 29.5 0.0 2.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KDO18141.1 - 1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO18141.1 - 0.0085 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 AKAP7_NLS PF10469.9 KDO18142.1 - 1.7e-31 109.7 0.0 2.9e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 KDO18142.1 - 1.8e-23 83.0 2.2 3.1e-23 82.3 2.2 1.4 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain ParcG PF10274.9 KDO18143.1 - 6.3e-43 147.0 0.0 7.9e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Elicitin PF00964.17 KDO18145.1 - 5.2e-06 26.5 0.1 1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Elicitin Med3 PF11593.8 KDO18145.1 - 0.8 8.8 6.1 1.1 8.3 6.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MORN PF02493.20 KDO18148.1 - 2.3e-14 52.3 11.5 0.00012 21.7 0.1 3.3 3 0 0 3 3 3 3 MORN repeat DJ-1_PfpI PF01965.24 KDO18149.1 - 1e-21 77.4 0.0 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KDO18149.1 - 0.061 12.4 0.0 0.15 11.1 0.0 1.6 1 1 1 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Elicitin PF00964.17 KDO18150.1 - 0.0024 17.9 1.1 0.0024 17.9 1.1 3.4 3 0 0 3 3 3 2 Elicitin FeS PF04060.13 KDO18150.1 - 0.052 13.2 0.4 0.13 11.9 0.4 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster Elicitin PF00964.17 KDO18151.1 - 5.1e-06 26.5 11.2 3.5e-05 23.8 2.7 6.6 7 2 0 7 7 7 2 Elicitin DUF1403 PF07183.11 KDO18151.1 - 0.022 14.3 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1403) Stm1_N PF09598.10 KDO18151.1 - 1.1 10.2 7.0 2.6 9.0 7.0 1.5 1 0 0 1 1 1 0 Stm1 Fer4_7 PF12838.7 KDO18151.1 - 2.3 8.9 7.7 19 6.0 0.1 3.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Triabin PF03973.13 KDO18151.1 - 5.4 6.9 10.6 1.1 9.2 0.3 3.7 4 0 0 4 4 4 0 Triabin GCP_N_terminal PF17681.1 KDO18152.1 - 5.2e-13 49.3 0.0 5.8e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF846 PF05832.12 KDO18153.1 - 3.5e-55 185.8 9.8 4.3e-55 185.6 9.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 KDO18153.1 - 0.056 13.8 8.3 1.1 9.6 0.8 2.2 2 0 0 2 2 2 0 YwiC-like protein UPF0014 PF03649.13 KDO18153.1 - 0.55 9.5 8.9 0.31 10.3 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) RabGAP-TBC PF00566.18 KDO18154.1 - 0.00066 19.4 0.0 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TLD PF07534.16 KDO18154.1 - 0.012 15.9 0.0 0.75 10.0 0.0 2.2 1 1 1 2 2 2 0 TLD TauD PF02668.16 KDO18156.1 - 3e-12 46.9 0.0 3.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Bac_small_YrzI PF09501.10 KDO18156.1 - 0.14 12.3 0.1 0.88 9.8 0.1 2.0 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Fijivirus_P9-2 PF06837.11 KDO18158.1 - 0.19 11.2 0.5 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Fijivirus P9-2 protein GMP_PDE_delta PF05351.11 KDO18159.1 - 0.078 13.0 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 GMP-PDE, delta subunit BAT PF15915.5 KDO18159.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Ank_2 PF12796.7 KDO18160.1 - 7.7e-15 55.3 0.5 2.2e-07 31.4 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO18160.1 - 9.7e-10 37.9 4.1 1.8 9.4 0.1 6.5 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KDO18160.1 - 3.9e-09 36.9 1.2 1.2e-05 25.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18160.1 - 4.7e-06 26.8 2.7 2 8.8 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO18160.1 - 0.062 13.8 7.9 1.9 9.1 0.1 4.5 5 0 0 5 5 5 0 Ankyrin repeat SDA1 PF05285.12 KDO18163.1 - 0.093 12.1 13.9 0.13 11.7 13.9 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 KDO18163.1 - 0.47 9.0 17.5 0.65 8.5 17.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 KDO18163.1 - 2.6 7.3 17.3 3.6 6.8 17.3 1.2 1 0 0 1 1 1 0 BUD22 Rtf2 PF04641.12 KDO18164.1 - 0.44 9.9 4.4 0.2 11.0 2.1 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 KDO18164.1 - 0.61 10.0 0.1 0.61 10.0 0.1 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Glycos_transf_1 PF00534.20 KDO18165.1 - 0.00098 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO18165.1 - 0.0022 18.4 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO18165.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 zf-HC2 PF13490.6 KDO18165.1 - 0.16 12.2 0.3 0.49 10.7 0.3 1.9 1 0 0 1 1 1 0 Putative zinc-finger Glycos_transf_1 PF00534.20 KDO18167.1 - 3e-11 43.2 0.0 4.4e-05 23.1 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO18167.1 - 1.4e-07 32.0 0.0 0.0052 17.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 VHP PF02209.19 KDO18167.1 - 0.12 12.4 0.2 49 4.1 0.0 3.5 3 0 0 3 3 3 0 Villin headpiece domain Glycos_transf_1 PF00534.20 KDO18168.1 - 9.5e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO18168.1 - 0.039 14.4 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Hydrolase_4 PF12146.8 KDO18169.1 - 1.3e-07 31.1 0.0 8.2e-06 25.3 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO18169.1 - 1.3e-06 28.3 0.1 0.00041 20.1 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO18169.1 - 2.9e-05 24.8 1.5 4.4e-05 24.2 1.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KDO18169.1 - 0.00035 20.3 0.1 0.00042 20.0 0.1 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KDO18169.1 - 0.011 15.6 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 KDO18169.1 - 0.039 13.6 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Ntox14 PF15522.6 KDO18170.1 - 0.023 14.1 2.5 0.87 9.0 0.3 2.2 1 1 0 2 2 2 0 Novel toxin 14 DUF1394 PF07159.12 KDO18171.1 - 2.1e-36 125.7 0.0 2.5e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Rad51 PF08423.11 KDO18173.1 - 1.3e-29 103.3 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KDO18173.1 - 2.1e-09 37.1 0.9 1.8e-08 34.1 0.9 2.3 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KDO18173.1 - 2.6e-08 33.7 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KDO18173.1 - 8e-06 25.5 0.3 0.00053 19.5 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KDO18173.1 - 0.00043 19.7 0.0 0.0075 15.6 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain NACHT PF05729.12 KDO18173.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KDO18173.1 - 0.046 13.5 0.4 0.2 11.4 0.1 2.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 KDO18173.1 - 0.096 13.2 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO18173.1 - 0.28 11.5 0.8 2 8.7 0.8 2.2 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KDO18173.1 - 0.28 10.3 0.1 0.46 9.6 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein Ank_2 PF12796.7 KDO18174.1 - 6.8e-23 81.1 1.8 1.2e-06 29.0 0.0 5.5 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO18174.1 - 4.7e-17 61.8 8.0 0.0011 19.2 0.1 10.9 7 4 5 12 12 12 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO18174.1 - 1.4e-15 57.4 5.7 0.00012 22.6 0.1 7.9 6 3 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18174.1 - 3.6e-10 39.2 2.5 0.16 12.6 0.0 9.2 9 1 1 10 10 10 1 Ankyrin repeat Ank PF00023.30 KDO18174.1 - 1e-05 25.7 0.6 25 5.5 0.0 7.6 7 3 1 8 8 8 1 Ankyrin repeat Ank_2 PF12796.7 KDO18177.1 - 8.7e-07 29.4 0.3 2.2e-06 28.2 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO18177.1 - 0.00062 20.0 1.4 0.44 10.9 0.3 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18177.1 - 0.0045 17.4 0.3 0.68 10.7 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KDO18177.1 - 0.0047 17.5 0.4 0.021 15.4 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Cnd1 PF12717.7 KDO18180.1 - 3.7e-05 23.8 3.1 0.13 12.3 0.1 3.8 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KDO18180.1 - 0.00011 22.7 0.1 0.21 12.2 0.0 4.0 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KDO18180.1 - 0.00054 20.0 15.3 7.4 7.1 0.0 9.0 10 1 1 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 KDO18180.1 - 0.00093 19.5 7.9 0.09 13.2 0.1 4.9 5 1 0 5 5 5 1 HEAT repeats UNC45-central PF11701.8 KDO18180.1 - 0.0022 18.0 0.1 0.6 10.1 0.1 3.5 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KDO18180.1 - 0.23 12.0 15.9 18 5.9 0.1 7.4 6 3 3 9 9 9 0 HEAT-like repeat RIX1 PF08167.12 KDO18180.1 - 2.8 7.7 5.2 2.7 7.7 0.1 3.4 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HECT PF00632.25 KDO18181.1 - 9.9e-66 222.3 0.0 1.3e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO18181.1 - 2.6e-05 23.4 1.9 5.9e-05 22.3 1.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KDO18181.1 - 0.012 15.0 0.5 0.022 14.1 0.5 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain bZIP_1 PF00170.21 KDO18184.1 - 0.031 14.4 5.3 0.053 13.6 5.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor ETF PF01012.21 KDO18185.1 - 0.055 13.4 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Peptidase_M14 PF00246.24 KDO18187.1 - 1.5e-31 110.3 0.0 1.8e-31 110.1 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase zf-MYND PF01753.18 KDO18188.1 - 1.3e-06 28.4 8.6 2e-06 27.7 8.6 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KDO18188.1 - 0.16 12.1 3.3 0.31 11.2 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_M14 PF00246.24 KDO18189.1 - 6.8e-33 114.7 0.0 9.2e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase TMEM89 PF15098.6 KDO18195.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 TMEM89 protein family VHL PF01847.16 KDO18196.1 - 1.3e-19 69.9 0.3 6.2e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 VHL beta domain C2 PF00168.30 KDO18196.1 - 3.8e-15 56.1 0.0 1.2e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain Ceramidase PF05875.12 KDO18199.1 - 9.4e-54 182.6 15.4 1.2e-53 182.2 15.4 1.1 1 0 0 1 1 1 1 Ceramidase ECF_trnsprt PF12822.7 KDO18199.1 - 5.1 7.2 7.5 0.86 9.7 2.8 2.2 2 1 1 3 3 3 0 ECF transporter, substrate-specific component Chorismate_bind PF00425.18 KDO18201.1 - 1.7e-86 290.0 0.0 2.3e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KDO18201.1 - 1.8e-15 57.2 0.0 3.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KDO18201.1 - 9.5e-08 32.4 0.1 3.3e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KDO18201.1 - 3.9e-06 26.8 0.0 8.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DEAD PF00270.29 KDO18203.1 - 2.3e-45 154.5 0.1 4.4e-45 153.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO18203.1 - 7e-27 94.0 0.0 1.9e-24 86.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO18203.1 - 0.00016 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KDO18204.1 - 8.5e-48 163.0 0.0 2.9e-47 161.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18204.1 - 8.9e-23 80.9 0.0 1.5e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO18204.1 - 9.8e-07 28.9 1.4 0.0015 18.5 0.1 2.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO18204.1 - 6.9e-06 25.6 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO18204.1 - 5.4e-05 22.1 0.0 7.9e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO18204.1 - 0.00044 19.7 0.0 0.033 13.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO18204.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KDO18204.1 - 0.22 10.4 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CorA PF01544.18 KDO18205.1 - 4.8e-08 32.7 8.0 1.6e-07 31.0 8.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EamA PF00892.20 KDO18207.1 - 3.5e-20 72.6 33.5 2.4e-10 40.7 14.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 KDO18208.1 - 7.4e-100 327.7 53.0 3.6e-18 65.9 0.8 6.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 KDO18208.1 - 1.3e-54 180.4 37.8 4.9e-07 29.9 0.1 11.8 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 KDO18208.1 - 7.3e-53 176.3 17.9 8.2e-10 39.0 0.4 8.0 6 1 2 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18208.1 - 2.1e-49 159.7 18.4 1.1e-05 25.4 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 KDO18208.1 - 4.8e-44 147.8 31.4 1.9e-07 31.2 1.5 9.9 5 3 6 11 11 11 9 Ankyrin repeats (many copies) DUF5535 PF17687.1 KDO18208.1 - 0.011 15.9 0.2 11 6.2 0.0 4.8 2 2 5 7 7 7 0 Family of unknown function (DUF5535) Nitro_FeMo-Co PF02579.17 KDO18208.1 - 0.012 15.9 2.0 9.3 6.7 0.1 4.0 2 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor BiPBP_C PF06832.12 KDO18208.1 - 0.017 15.1 3.7 3.4 7.8 0.0 4.8 3 1 1 5 5 5 0 Penicillin-Binding Protein C-terminus Family Mur_ligase PF01225.25 KDO18208.1 - 0.022 15.1 0.4 0.61 10.4 0.1 3.4 2 2 1 3 3 3 0 Mur ligase family, catalytic domain YlzJ PF14035.6 KDO18208.1 - 0.2 11.9 0.0 49 4.2 0.0 3.8 4 1 1 5 5 5 0 YlzJ-like protein VWA_3_C PF18571.1 KDO18208.1 - 0.45 10.4 7.6 75 3.3 0.0 6.0 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain EccE PF11203.8 KDO18208.1 - 0.75 10.2 10.4 0.098 13.0 1.5 3.5 2 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE ENTH PF01417.20 KDO18210.1 - 2.3e-10 40.6 0.0 2.7e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KDO18210.1 - 0.00022 20.3 0.0 0.00024 20.2 0.0 1.0 1 0 0 1 1 1 1 ANTH domain MatE PF01554.18 KDO18211.1 - 6.7e-44 149.4 33.5 8.7e-24 84.0 8.3 2.3 2 0 0 2 2 2 2 MatE PP2C PF00481.21 KDO18212.1 - 1.5e-34 119.8 0.0 3.2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 KDO18212.1 - 5.9e-22 78.3 0.0 9.4e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO18212.1 - 1.4e-19 70.0 0.1 8.6e-13 48.2 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO18212.1 - 2.6e-09 36.7 0.0 4.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 KDO18212.1 - 6.7e-06 25.9 0.0 8.3e-05 22.3 0.0 2.4 3 0 0 3 3 3 1 Protein phosphatase 2C Arm PF00514.23 KDO18213.1 - 3.1e-169 544.7 129.4 1.7e-09 37.4 0.0 43.9 47 0 0 47 47 47 30 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO18213.1 - 1.2e-32 112.1 87.0 0.032 14.6 0.2 24.3 12 8 14 27 27 27 14 HEAT repeats Arm_2 PF04826.13 KDO18213.1 - 2.1e-28 99.5 13.5 5.4e-05 22.8 0.0 13.9 6 2 6 15 15 15 10 Armadillo-like HEAT_EZ PF13513.6 KDO18213.1 - 1.3e-20 73.4 103.3 0.00049 20.5 0.0 22.9 21 5 6 27 27 27 10 HEAT-like repeat V-ATPase_H_N PF03224.14 KDO18213.1 - 4.2e-20 72.3 1.7 0.068 12.4 0.0 11.0 4 3 2 7 7 7 6 V-ATPase subunit H KAP PF05804.12 KDO18213.1 - 1.2e-11 43.6 0.0 0.021 13.0 0.0 7.8 7 1 0 7 7 7 3 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KDO18213.1 - 8.2e-06 25.9 11.2 5.4 7.0 0.1 8.6 7 2 2 9 9 9 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KDO18213.1 - 0.0028 17.2 8.4 0.14 11.7 0.0 5.0 6 0 0 6 6 6 1 CLASP N terminal HEAT PF02985.22 KDO18213.1 - 0.07 13.4 100.8 0.074 13.3 0.1 27.9 33 0 0 33 33 31 0 HEAT repeat Nipped-B_C PF12830.7 KDO18213.1 - 0.089 12.7 11.4 44 3.9 0.0 7.4 7 0 0 7 7 7 0 Sister chromatid cohesion C-terminus NopRA1 PF16201.5 KDO18213.1 - 0.17 11.4 9.8 6.6 6.3 0.0 6.0 7 0 0 7 7 7 0 Nucleolar pre-ribosomal-associated protein 1 Cas_Csx9 PF09658.10 KDO18213.1 - 0.21 10.7 0.9 8 5.5 0.0 3.5 4 1 1 5 5 5 0 CRISPR-associated protein (Cas_Csx9) CTNNBL PF08216.11 KDO18213.1 - 0.31 11.2 8.9 76 3.5 0.0 7.7 9 0 0 9 9 8 0 Catenin-beta-like, Arm-motif containing nuclear Vps52 PF04129.12 KDO18214.1 - 6.2e-06 25.2 0.1 1.5e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family COG6 PF06419.11 KDO18214.1 - 0.01 14.1 0.1 0.019 13.2 0.0 1.4 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Pkinase PF00069.25 KDO18215.1 - 3.6e-39 134.7 0.0 1.8e-38 132.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18215.1 - 4.7e-36 124.4 0.0 1.7e-34 119.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO18215.1 - 0.0011 17.8 2.3 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO18215.1 - 0.037 13.4 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO18215.1 - 0.13 11.2 0.6 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KDO18215.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Spermine_synth PF01564.17 KDO18217.1 - 0.0073 15.7 0.1 0.0098 15.3 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Pkinase PF00069.25 KDO18218.1 - 3.1e-40 138.2 0.0 2.1e-38 132.2 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18218.1 - 5.1e-34 117.7 0.0 3.3e-32 111.8 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO18218.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO18218.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO18218.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO18218.1 - 0.042 12.8 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KDO18218.1 - 0.057 12.2 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KDO18218.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 KDO18219.1 - 8e-45 153.2 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18219.1 - 3e-41 141.4 0.0 3.6e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO18219.1 - 0.0022 16.8 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO18219.1 - 0.0077 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO18219.1 - 0.068 12.1 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KDO18220.1 - 3.5e-13 49.4 0.0 2e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18220.1 - 3e-12 46.5 0.0 6.3e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KDO18220.1 - 0.00022 20.9 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KDO18221.1 - 2.4e-65 220.5 0.0 3.1e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18221.1 - 3.9e-29 101.7 0.0 9.6e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18221.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO18221.1 - 0.00017 21.0 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO18221.1 - 0.011 14.7 0.1 0.019 13.9 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KDO18221.1 - 0.017 14.8 0.3 0.043 13.4 0.3 1.6 1 0 0 1 1 1 0 RIO1 family Mal_decarbox_Al PF16957.5 KDO18221.1 - 0.038 12.3 0.0 0.059 11.7 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter FTA2 PF13095.6 KDO18221.1 - 0.039 13.6 0.1 0.088 12.4 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KDO18221.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KDO18221.1 - 0.17 10.7 0.1 0.29 9.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO18221.1 - 0.3 11.0 1.4 1.1 9.2 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_11 PF08241.12 KDO18227.1 - 1.7e-09 38.2 0.1 2.4e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO18227.1 - 1.8e-08 34.9 0.1 2.8e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO18227.1 - 9.6e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KDO18227.1 - 4.8e-06 26.4 0.0 5.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18227.1 - 0.0048 17.6 0.1 0.0062 17.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO18227.1 - 0.025 14.1 0.1 0.04 13.5 0.1 1.3 1 1 0 1 1 1 0 Methyltransferase small domain EI24 PF07264.11 KDO18228.1 - 1 9.6 8.3 2 8.6 8.4 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) COPI_assoc PF08507.10 KDO18228.1 - 8.7 6.4 10.8 0.49 10.4 2.0 2.7 2 1 0 2 2 2 0 COPI associated protein HEAT_EZ PF13513.6 KDO18230.1 - 0.026 15.0 0.7 4.8 7.8 0.0 3.0 2 1 1 3 3 3 0 HEAT-like repeat Adaptin_N PF01602.20 KDO18230.1 - 0.075 11.6 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Kazal_1 PF00050.21 KDO18231.1 - 5.9e-36 122.3 33.4 8.8e-10 38.4 3.8 4.3 2 2 2 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KDO18231.1 - 2.5e-34 117.1 38.4 9.4e-10 38.5 3.6 4.7 4 1 1 5 5 5 4 Kazal-type serine protease inhibitor domain FYVE PF01363.21 KDO18232.1 - 0.0032 17.6 8.6 0.0079 16.3 8.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 KDO18232.1 - 0.015 15.0 5.1 0.028 14.1 5.1 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DZR PF12773.7 KDO18232.1 - 0.045 13.8 8.6 0.2 11.7 8.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 KDO18232.1 - 0.23 11.8 3.7 0.75 10.2 3.7 1.9 1 0 0 1 1 1 0 C1 domain zf-C3HC4_3 PF13920.6 KDO18232.1 - 0.74 9.7 11.3 0.21 11.5 4.3 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KDO18232.1 - 2.1 8.4 11.0 15 5.6 5.6 2.7 1 1 1 2 2 2 0 zinc-ribbons zf-B_box PF00643.24 KDO18232.1 - 2.7 8.2 13.5 0.73 10.0 7.6 2.7 2 1 0 2 2 2 0 B-box zinc finger TIR_2 PF13676.6 KDO18233.1 - 4.9e-14 52.9 0.0 1e-13 51.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR-like PF10137.9 KDO18233.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain SAM_1 PF00536.30 KDO18233.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) adh_short PF00106.25 KDO18234.1 - 5e-32 110.9 0.2 4.3e-27 94.9 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO18234.1 - 7e-20 71.6 0.8 4.1e-19 69.1 0.8 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO18234.1 - 6e-11 42.6 0.5 1.1e-10 41.7 0.5 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO18234.1 - 6.7e-07 29.0 0.0 9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KDO18234.1 - 0.011 16.0 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain YjeF_N PF03853.15 KDO18234.1 - 0.027 14.3 0.2 0.057 13.3 0.2 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.8 KDO18234.1 - 0.029 14.1 0.1 0.079 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KDO18234.1 - 0.031 14.4 0.1 0.053 13.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KDO18234.1 - 0.2 11.0 0.1 0.34 10.2 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Exo_endo_phos PF03372.23 KDO18236.1 - 4.8e-13 49.2 1.8 1.3e-12 47.7 1.8 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EGF_2 PF07974.13 KDO18240.1 - 1.1e-18 67.3 106.0 4.6e-06 26.9 5.3 10.6 11 0 0 11 11 11 6 EGF-like domain EGF PF00008.27 KDO18240.1 - 2.2e-05 24.6 12.7 9.2e-05 22.7 3.3 9.8 10 0 0 10 10 10 5 EGF-like domain Laminin_EGF PF00053.24 KDO18240.1 - 0.00015 21.8 72.7 0.0044 17.1 4.8 8.5 8 1 0 8 8 8 6 Laminin EGF domain Helicase_C PF00271.31 KDO18241.1 - 2.4e-20 72.9 0.0 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain fragilysinNterm PF16376.5 KDO18241.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of fragilysin PAN_4 PF14295.6 KDO18242.1 - 9.6e-43 143.9 59.7 7.6e-08 32.2 1.5 7.9 7 0 0 7 7 7 6 PAN domain PAN_1 PF00024.26 KDO18242.1 - 5.8e-42 141.5 35.7 1e-07 31.8 0.2 9.2 6 3 2 9 9 9 8 PAN domain PAN_2 PF08276.11 KDO18242.1 - 1.1e-07 31.9 44.6 0.049 13.8 0.4 7.5 7 0 0 7 7 7 5 PAN-like domain PIG-L PF02585.17 KDO18242.1 - 0.00044 20.9 0.0 0.00091 19.9 0.0 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_3 PF08277.12 KDO18242.1 - 0.0094 15.7 4.0 0.0094 15.7 4.0 6.8 7 0 0 7 7 7 3 PAN-like domain MANEC PF07502.14 KDO18242.1 - 0.022 15.0 0.5 0.022 15.0 0.5 6.5 8 0 0 8 8 8 0 MANEC domain RLAN PF14401.6 KDO18242.1 - 0.16 11.6 0.0 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain GRDP-like PF07173.12 KDO18244.1 - 5.2e-15 56.3 0.4 5.1e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Glycine-rich domain-containing protein-like Myb_DNA-binding PF00249.31 KDO18245.1 - 6.7e-10 39.0 0.7 8.8e-10 38.6 0.1 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO18245.1 - 0.033 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KDO18245.1 - 0.07 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain PH PF00169.29 KDO18246.1 - 6.5e-14 52.3 0.0 9.6e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_2 PF08458.10 KDO18246.1 - 0.00033 21.0 0.2 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Plant pleckstrin homology-like region PH_9 PF15410.6 KDO18246.1 - 0.023 15.0 0.6 0.094 13.1 0.7 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO18246.1 - 0.075 13.1 0.1 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_13 PF16652.5 KDO18246.1 - 0.15 11.9 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain NAD_binding_6 PF08030.12 KDO18247.1 - 4.5e-34 117.8 0.0 8.2e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO18247.1 - 7e-21 74.4 0.0 1.8e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KDO18247.1 - 3.4e-15 56.3 6.0 7.2e-15 55.2 6.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KDO18247.1 - 0.0013 19.4 0.0 0.0057 17.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Ldt_C PF17969.1 KDO18247.1 - 0.084 13.6 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 L,D-transpeptidase C-terminal domain EF-hand_7 PF13499.6 KDO18247.1 - 0.14 12.6 0.1 0.41 11.1 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair MORN PF02493.20 KDO18249.1 - 4.3e-06 26.3 10.8 0.0013 18.5 3.5 3.7 4 0 0 4 4 4 2 MORN repeat Glyco_hydro_72 PF03198.14 KDO18250.1 - 2.4e-36 125.6 5.5 3.6e-35 121.7 5.5 2.2 1 1 0 1 1 1 1 Glucanosyltransferase SwrA PF17423.2 KDO18250.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Swarming motility protein DUF16 PF01519.16 KDO18251.1 - 0.003 18.0 12.1 0.0067 16.9 4.6 2.5 2 0 0 2 2 2 1 Protein of unknown function DUF16 MOSC_N PF03476.16 KDO18251.1 - 0.0034 17.2 1.2 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain His_Phos_2 PF00328.22 KDO18251.1 - 0.005 16.2 3.2 0.0075 15.7 3.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF725 PF05267.12 KDO18251.1 - 0.01 15.8 2.4 0.021 14.8 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF2408 PF10303.9 KDO18251.1 - 0.013 16.1 14.0 0.19 12.3 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF3145 PF11343.8 KDO18251.1 - 0.02 14.5 0.4 0.048 13.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Fez1 PF06818.15 KDO18251.1 - 0.048 14.1 23.7 0.027 14.9 5.5 3.0 1 1 1 2 2 2 0 Fez1 bZIP_Maf PF03131.17 KDO18251.1 - 0.16 12.5 19.9 0.075 13.6 3.7 4.0 2 2 2 4 4 4 0 bZIP Maf transcription factor JIP_LZII PF16471.5 KDO18251.1 - 0.32 11.2 18.1 1.8 8.8 5.4 3.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Fzo_mitofusin PF04799.13 KDO18251.1 - 0.42 10.1 17.7 0.19 11.3 0.8 3.4 2 1 2 4 4 4 0 fzo-like conserved region Cob_adeno_trans PF01923.18 KDO18251.1 - 0.48 10.5 12.7 0.16 12.1 5.1 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Cep57_CLD PF14073.6 KDO18251.1 - 0.63 10.0 23.2 0.41 10.6 12.3 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Plk4_PB2 PF18409.1 KDO18251.1 - 1 10.1 4.5 2.4 8.9 0.6 2.8 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 TEX13 PF15186.6 KDO18251.1 - 1.1 8.9 25.8 0.53 10.0 5.7 3.2 2 1 0 3 3 3 0 Testis-expressed sequence 13 protein family HAUS-augmin3 PF14932.6 KDO18251.1 - 1.6 8.3 28.3 0.46 10.0 15.2 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2937 PF11157.8 KDO18251.1 - 2.2 8.0 9.6 0.071 12.8 2.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) TPR_MLP1_2 PF07926.12 KDO18251.1 - 2.4 8.2 29.6 0.72 9.9 16.6 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 KDO18251.1 - 2.8 8.1 27.7 1.2 9.3 5.1 4.6 3 2 1 4 4 4 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 KDO18251.1 - 3.6 7.8 28.1 0.76 10.0 5.4 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 KDO18251.1 - 4.1 7.8 14.0 1.7 9.0 5.5 3.5 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM76 PF16046.5 KDO18251.1 - 5.7 6.2 12.9 5 6.4 6.6 2.2 2 0 0 2 2 2 0 FAM76 protein CENP-H PF05837.12 KDO18251.1 - 5.9 7.4 27.2 0.11 12.9 3.0 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KDO18251.1 - 5.9 7.1 34.1 17 5.5 19.2 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc29 PF17082.5 KDO18251.1 - 7.2 6.4 13.3 3.1 7.6 7.8 2.8 1 1 0 2 2 2 0 Spindle Pole Component 29 YabA PF06156.13 KDO18251.1 - 9.2 7.0 20.6 1.2 9.8 0.6 3.9 2 2 1 3 3 3 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 KDO18251.1 - 9.5 6.9 27.4 4.7 7.9 1.5 4.4 1 1 4 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Peptidase_S8 PF00082.22 KDO18253.1 - 4.9e-37 127.8 2.5 1.3e-36 126.4 2.5 1.7 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 KDO18255.1 - 7.9e-19 68.0 10.6 0.00057 20.4 0.2 6.2 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18255.1 - 6.9e-15 55.2 24.8 0.0009 19.8 0.1 7.4 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18255.1 - 1.2e-09 38.2 19.1 1.2 9.6 0.0 9.0 6 2 3 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18255.1 - 6.4e-08 32.3 14.2 1.9 9.3 0.1 9.8 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 KDO18255.1 - 4 8.1 13.9 7.9 7.1 0.1 6.2 4 3 1 5 5 5 0 Ankyrin repeat Peptidase_S8 PF00082.22 KDO18256.1 - 4.4e-34 118.1 3.2 3.7e-32 111.8 3.2 2.3 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 KDO18258.1 - 1.7e-34 118.3 6.1 9.3e-18 64.6 0.6 3.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO18258.1 - 9.3e-29 99.1 4.8 9.3e-14 51.3 0.7 3.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO18258.1 - 1.7e-23 82.7 1.0 5.3e-12 46.0 0.1 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO18258.1 - 4.3e-19 68.0 3.9 3.1e-07 30.5 0.1 4.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KDO18258.1 - 6.2e-19 66.1 0.1 9e-07 28.7 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat YjgF_endoribonc PF14588.6 KDO18258.1 - 0.08 13.1 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease Pkinase PF00069.25 KDO18259.1 - 0.045 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain DZR PF12773.7 KDO18259.1 - 0.49 10.5 12.5 2.5 8.2 12.6 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 KDO18259.1 - 4 7.7 11.4 3.6 7.8 1.4 2.4 1 1 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KDO18260.1 - 1.3e-10 41.4 10.1 6.7e-09 35.9 10.1 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO18260.1 - 4.2e-09 36.1 0.8 4.2e-09 36.1 0.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO18260.1 - 2.4e-08 34.0 0.0 6.3e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 PX domain zf-rbx1 PF12678.7 KDO18260.1 - 9.1e-08 32.3 7.4 2.1e-07 31.1 7.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO18260.1 - 2.5e-07 30.4 5.0 5.4e-07 29.4 5.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO18260.1 - 2.4e-06 27.2 3.9 9.1e-05 22.1 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO18260.1 - 3.2e-05 23.8 2.8 4.1e-05 23.5 1.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO18260.1 - 7.2e-05 22.7 5.7 0.00027 20.8 5.7 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO18260.1 - 8.6e-05 22.3 0.4 8.6e-05 22.3 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO18260.1 - 0.00023 21.0 0.5 0.00023 21.0 0.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO18260.1 - 0.0016 18.5 3.6 0.0034 17.4 3.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KDO18260.1 - 0.018 15.3 3.2 0.039 14.2 3.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Sigma70_ner PF04546.13 KDO18260.1 - 0.13 12.1 1.2 0.23 11.3 1.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RINGv PF12906.7 KDO18260.1 - 0.16 12.1 5.5 0.12 12.5 1.1 2.4 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 KDO18260.1 - 0.17 12.0 6.0 0.27 11.4 1.7 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO18260.1 - 0.89 9.4 6.9 0.45 10.4 1.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KDO18260.1 - 1.5 8.5 9.8 0.037 13.7 2.9 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KDO18261.1 - 2e-13 50.4 8.1 2e-13 50.4 8.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KDO18261.1 - 1.1e-08 34.8 9.3 1.8e-08 34.1 7.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO18261.1 - 1.5e-08 34.5 4.8 3.9e-08 33.2 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KDO18261.1 - 1.6e-08 34.7 10.9 5.3e-08 33.0 10.2 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO18261.1 - 4.4e-07 29.6 10.6 4.4e-07 29.6 10.6 2.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO18261.1 - 2.1e-06 27.6 8.7 5.5e-06 26.2 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KDO18261.1 - 2.2e-06 27.3 4.5 6.6e-06 25.8 4.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KDO18261.1 - 2.5e-05 24.2 7.4 6.4e-05 22.9 7.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KDO18261.1 - 0.00082 19.5 11.1 0.0011 19.1 9.0 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain RINGv PF12906.7 KDO18261.1 - 0.0017 18.5 6.1 0.0041 17.2 5.7 1.9 1 1 0 1 1 1 1 RING-variant domain Prok-RING_1 PF14446.6 KDO18261.1 - 0.0026 17.6 2.6 0.0026 17.6 2.6 2.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KDO18261.1 - 0.004 17.0 10.7 0.004 17.0 10.7 2.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO18261.1 - 0.015 15.1 13.8 0.031 14.1 6.3 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KDO18261.1 - 0.023 14.5 5.5 0.057 13.2 5.5 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KDO18261.1 - 0.068 12.8 10.4 0.16 11.7 10.4 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KDO18261.1 - 0.16 11.8 10.5 0.31 10.9 10.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HTH_43 PF09904.9 KDO18261.1 - 0.21 11.6 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix zf-C3HC4_4 PF15227.6 KDO18261.1 - 0.62 10.3 11.9 11 6.3 10.1 3.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 KDO18261.1 - 7.4 6.8 13.1 0.097 12.9 3.9 2.1 1 1 1 2 2 2 0 Zinc-ribbon like family PX PF00787.24 KDO18262.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-RING_2 PF13639.6 KDO18262.1 - 0.0072 16.6 10.1 0.018 15.3 10.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO18262.1 - 0.064 13.0 5.7 0.15 11.8 5.7 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KDO18262.1 - 0.64 10.0 8.2 1.2 9.1 8.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RVT_1 PF00078.27 KDO18263.1 - 4.7e-14 52.4 0.0 8.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KDO18263.1 - 4e-06 26.7 0.0 8.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KDO18263.1 - 0.0042 16.6 0.1 0.0079 15.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Questin_oxidase PF14027.6 KDO18263.1 - 0.073 12.6 0.0 1.3 8.5 0.0 2.2 2 1 0 2 2 2 0 Questin oxidase-like zf-RING_2 PF13639.6 KDO18264.1 - 6.2e-14 52.0 3.1 4.5e-11 42.9 1.1 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 KDO18264.1 - 8.8e-11 41.9 5.6 4e-09 36.6 5.6 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO18264.1 - 8.3e-10 38.2 0.4 2.4e-05 24.0 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO18264.1 - 4.6e-09 36.0 5.7 2.7e-08 33.5 1.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO18264.1 - 5.7e-06 26.3 0.6 5.7e-06 26.3 0.6 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO18264.1 - 8.3e-06 25.7 4.1 2.4e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO18264.1 - 1.1e-05 25.3 2.2 8e-05 22.6 1.3 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO18264.1 - 1.5e-05 24.7 8.0 8.6e-05 22.3 6.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO18264.1 - 1.6e-05 24.6 0.5 1.6e-05 24.6 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO18264.1 - 0.00022 21.0 0.4 0.00022 21.0 0.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KDO18264.1 - 0.0066 16.6 1.9 0.0066 16.6 1.9 2.3 2 1 1 3 3 3 1 RING-variant domain Zn_ribbon_17 PF17120.5 KDO18264.1 - 0.028 14.0 1.6 0.028 14.0 1.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO18264.1 - 0.064 13.1 2.1 0.18 11.6 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 KDO18264.1 - 8.3 6.5 10.7 0.083 12.9 2.0 2.1 2 0 0 2 2 2 0 Zinc-finger zf-RING_2 PF13639.6 KDO18265.1 - 9e-14 51.5 10.1 1.8e-13 50.6 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO18265.1 - 6.4e-09 35.5 12.4 7.2e-09 35.4 10.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO18265.1 - 3.5e-08 33.1 7.5 6.8e-08 32.1 7.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO18265.1 - 4.3e-08 33.3 11.8 1.1e-07 32.1 11.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO18265.1 - 4e-07 29.8 10.5 8.4e-07 28.8 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO18265.1 - 7.2e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 PX domain zf-RING_UBOX PF13445.6 KDO18265.1 - 1.7e-06 28.0 6.4 3.4e-06 27.0 6.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO18265.1 - 1e-05 25.4 9.2 1.9e-05 24.5 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO18265.1 - 6.7e-05 22.7 6.4 0.00014 21.6 6.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO18265.1 - 0.00018 21.5 9.3 0.00099 19.1 9.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO18265.1 - 0.0031 17.3 13.5 0.0067 16.3 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KDO18265.1 - 0.011 15.8 10.5 0.032 14.3 10.5 1.8 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KDO18265.1 - 0.093 12.4 12.3 0.25 11.0 12.4 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO18265.1 - 1.4 8.7 7.0 3.8 7.4 7.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 KDO18265.1 - 9.6 6.3 13.3 0.096 12.7 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger zf-RING_2 PF13639.6 KDO18266.1 - 4.9e-11 42.8 8.2 4.9e-11 42.8 8.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO18266.1 - 1.5e-08 34.8 7.9 3.5e-08 33.6 7.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO18266.1 - 2.2e-07 30.6 8.5 4.3e-07 29.7 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO18266.1 - 5.5e-07 29.6 0.0 9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 KDO18266.1 - 2.1e-06 27.4 5.0 2.1e-06 27.4 5.0 2.4 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO18266.1 - 2.1e-06 27.5 11.1 9.5e-06 25.4 11.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO18266.1 - 2.8e-06 27.3 4.5 1.1e-05 25.4 4.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO18266.1 - 8.2e-06 25.7 7.2 1.8e-05 24.6 7.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_16 PF17034.5 KDO18266.1 - 0.00021 21.5 1.4 0.00041 20.6 1.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family zf-RING_UBOX PF13445.6 KDO18266.1 - 0.00063 19.7 2.0 0.00063 19.7 2.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO18266.1 - 0.00068 19.4 7.5 0.0018 18.1 7.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO18266.1 - 0.0089 15.9 8.4 0.056 13.3 8.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KDO18266.1 - 0.041 14.0 7.1 0.21 11.8 7.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain CTU2 PF10288.9 KDO18266.1 - 0.27 11.5 1.8 0.38 11.0 0.1 1.9 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 RINGv PF12906.7 KDO18266.1 - 0.34 11.1 7.0 1.1 9.4 7.0 1.9 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KDO18266.1 - 5.6 6.7 10.1 4.7 6.9 7.8 2.1 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KDO18266.1 - 6.3 7.0 8.9 0.77 10.0 2.8 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Asp PF00026.23 KDO18267.1 - 1.6e-45 155.9 0.0 2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO18267.1 - 3.4e-11 43.7 0.1 1.7e-06 28.4 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KDO18267.1 - 0.051 14.2 0.0 2 9.1 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease Peptidase_C1 PF00112.23 KDO18268.1 - 3.7e-17 63.1 0.3 5.6e-17 62.6 0.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KDO18268.1 - 1.4e-12 47.8 0.2 3.3e-12 46.7 0.2 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3464 PF11947.8 KDO18270.1 - 0.96 9.2 5.2 1.4 8.7 5.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S8 PF00082.22 KDO18274.1 - 4.2e-35 121.5 1.5 7.5e-35 120.6 1.5 1.5 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 KDO18275.1 - 8.4e-34 117.2 3.1 1.3e-33 116.5 3.1 1.3 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 KDO18275.1 - 2.2e-13 50.6 0.5 3.8e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Peptidase_S8 PF00082.22 KDO18277.1 - 5.5e-36 124.4 1.2 1.5e-35 122.9 1.2 1.8 1 1 0 1 1 1 1 Subtilase family PAN_4 PF14295.6 KDO18278.1 - 2.7e-16 59.2 16.1 5.4e-08 32.6 3.2 2.5 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 KDO18278.1 - 8.4e-14 51.3 11.4 1e-06 28.6 4.0 2.1 1 1 1 2 2 2 2 PAN domain PAN_2 PF08276.11 KDO18278.1 - 0.033 14.3 6.9 0.033 14.3 6.9 2.4 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.12 KDO18278.1 - 0.077 12.8 13.7 0.31 10.9 1.7 2.2 2 0 0 2 2 2 0 PAN-like domain PAN_4 PF14295.6 KDO18279.1 - 1.2e-09 37.9 4.2 2.3e-09 37.0 4.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KDO18279.1 - 0.00012 22.0 2.8 0.00017 21.5 2.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KDO18279.1 - 0.28 11.0 5.3 0.3 10.9 3.8 1.8 1 1 1 2 2 2 0 PAN-like domain RNase_T PF00929.24 KDO18280.1 - 9.7e-15 55.5 0.1 1.5e-14 54.9 0.1 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KDO18280.1 - 0.012 15.4 0.0 0.055 13.2 0.0 2.1 1 1 0 1 1 1 0 3'-5' exonuclease MFS_2 PF13347.6 KDO18281.1 - 1.4e-07 30.5 11.8 1.4e-07 30.5 11.8 3.5 3 1 1 4 4 4 3 MFS/sugar transport protein MobA_MobL PF03389.15 KDO18282.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 MobA/MobL family HTH_23 PF13384.6 KDO18283.1 - 0.004 16.9 0.2 0.0092 15.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_22 PF13309.6 KDO18283.1 - 0.0061 16.6 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_11 PF08279.12 KDO18283.1 - 0.049 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 KDO18283.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KDO18283.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 NSP11 PF06471.12 KDO18283.1 - 0.11 11.0 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 NSP11 GntR PF00392.21 KDO18283.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family RSN1_7TM PF02714.15 KDO18285.1 - 4e-07 29.6 5.0 4e-07 29.6 5.0 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KDO18285.1 - 3.5e-05 24.1 4.2 8.9e-05 22.8 0.2 2.9 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter DUF4279 PF14106.6 KDO18285.1 - 0.038 14.2 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) RRM_1 PF00076.22 KDO18285.1 - 0.084 12.7 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Telomere_reg-2 PF10193.9 KDO18285.1 - 0.092 13.2 0.7 0.21 12.1 0.7 1.5 1 0 0 1 1 1 0 Telomere length regulation protein WD40 PF00400.32 KDO18286.1 - 7.7e-15 55.0 22.3 0.18 12.7 0.3 8.9 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO18286.1 - 5.2e-09 36.3 1.3 0.085 13.2 0.0 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 KDO18286.1 - 4.8e-05 23.1 0.1 0.00014 21.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO18286.1 - 6.1e-05 23.4 0.1 0.00016 22.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO18286.1 - 6.8e-05 22.2 0.3 0.00017 20.9 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KDO18286.1 - 0.00013 21.3 0.5 0.00036 19.9 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO18286.1 - 0.0015 18.3 0.2 0.0051 16.6 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain His_Phos_1 PF00300.22 KDO18286.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) CREPT PF16566.5 KDO18287.1 - 0.038 14.2 0.1 0.038 14.2 0.1 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PH PF00169.29 KDO18290.1 - 2.7e-08 34.3 0.0 1.6e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO18290.1 - 0.0001 22.7 0.5 0.0011 19.3 0.5 2.2 1 1 1 2 2 2 1 Pleckstrin homology domain Acyltransferase PF01553.21 KDO18293.1 - 2.8e-17 62.6 0.0 5.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KDO18293.1 - 6.5e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus YdaS_antitoxin PF15943.5 KDO18296.1 - 0.035 14.0 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF1645 PF07816.11 KDO18296.1 - 9.1 6.8 8.3 3.4 8.2 4.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) Pkinase_Tyr PF07714.17 KDO18297.1 - 7.5e-31 107.3 0.0 1.5e-30 106.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18297.1 - 1.4e-23 83.6 0.0 2.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Herpes_gE PF02480.16 KDO18297.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kdo PF06293.14 KDO18297.1 - 0.055 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCAF_N PF06466.11 KDO18297.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Vps62 PF06101.11 KDO18298.1 - 0.095 11.0 0.1 1.5 7.0 0.0 2.0 1 1 0 2 2 2 0 Vacuolar protein sorting-associated protein 62 C1_2 PF03107.16 KDO18299.1 - 0.0031 17.8 0.1 0.0066 16.7 0.1 1.5 1 0 0 1 1 1 1 C1 domain TPR_12 PF13424.6 KDO18299.1 - 0.05 13.9 1.8 0.081 13.2 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO18299.1 - 0.14 12.0 0.4 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 KDO18300.1 - 6.3e-19 68.1 38.2 9.3e-19 67.5 38.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO18300.1 - 2.2e-16 59.5 34.4 3.9e-16 58.7 34.4 1.4 1 1 0 1 1 1 1 Amino acid permease OppC_N PF12911.7 KDO18300.1 - 0.044 13.8 0.6 4.2 7.4 0.6 3.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C EVI2A PF05399.11 KDO18300.1 - 1.7 8.2 6.1 4.7 6.7 1.0 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF4212 PF13937.6 KDO18300.1 - 4.9 7.6 8.6 2.9 8.3 0.1 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4212) YCII PF03795.14 KDO18304.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain Epimerase PF01370.21 KDO18305.1 - 3.1e-25 89.0 0.0 4.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KDO18305.1 - 5.3e-20 72.1 0.0 4.8e-17 62.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KDO18305.1 - 4.5e-12 45.7 0.0 6.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KDO18305.1 - 5.1e-10 38.8 0.0 7.1e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KDO18305.1 - 7.3e-09 35.2 0.0 3.4e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KDO18305.1 - 8.2e-07 28.4 0.0 9.5e-06 25.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KDO18305.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding MULE PF10551.9 KDO18306.1 - 0.00032 21.1 0.0 0.00078 19.8 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Pkinase PF00069.25 KDO18307.1 - 4e-64 216.5 0.0 5.4e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18307.1 - 8.2e-34 117.0 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO18307.1 - 0.00023 21.2 0.0 0.0019 18.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO18307.1 - 0.0025 17.2 0.0 0.062 12.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO18307.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4586 PF15239.6 KDO18309.1 - 0.003 17.8 0.8 0.0049 17.1 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) zf-rbx1 PF12678.7 KDO18310.1 - 5.2e-08 33.1 0.3 7.3e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KDO18310.1 - 2.9e-07 30.7 0.4 4.4e-07 30.1 0.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KDO18310.1 - 1.2e-05 25.3 0.1 1.8e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KDO18310.1 - 3.3e-05 23.7 0.2 4.6e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO18310.1 - 0.0014 18.3 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KDO18310.1 - 0.003 17.4 0.4 0.0047 16.7 0.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SAP PF02037.27 KDO18310.1 - 0.0065 16.2 0.4 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 KDO18310.1 - 0.0094 15.8 5.3 0.022 14.6 5.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO18310.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 KDO18310.1 - 0.069 13.3 0.7 0.12 12.5 0.7 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO18310.1 - 0.13 12.5 3.5 0.33 11.2 3.5 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 KDO18310.1 - 0.16 11.9 0.3 0.16 11.9 0.3 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 KDO18310.1 - 0.16 12.0 2.2 0.15 12.1 0.9 1.7 1 1 1 2 2 2 0 RING-type zinc-finger Acyltransferase PF01553.21 KDO18311.1 - 7.6e-14 51.5 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase ABC_tran PF00005.27 KDO18313.1 - 1.1e-10 42.2 0.0 7.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SbcCD_C PF13558.6 KDO18313.1 - 0.0018 18.4 0.1 0.022 15.0 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KDO18313.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO18313.1 - 0.028 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Lipocalin_3 PF12702.7 KDO18313.1 - 0.035 14.2 0.1 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipocalin-like Pkinase PF00069.25 KDO18314.1 - 4.2e-35 121.4 0.0 4.7e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18314.1 - 1.3e-33 116.3 0.0 1.5e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18314.1 - 0.0014 18.0 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO18314.1 - 0.0034 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO18314.1 - 0.0055 15.5 0.0 0.0074 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO18314.1 - 0.04 13.3 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 KDO18315.1 - 1.8e-06 28.5 0.7 1.3e-05 25.7 0.2 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18315.1 - 2.3e-05 24.9 0.1 4.7e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18315.1 - 0.00027 21.1 0.6 0.75 10.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO18315.1 - 0.0043 17.3 0.5 0.095 13.0 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Dymeclin PF09742.9 KDO18316.1 - 3.5e-68 230.6 6.0 4e-68 230.4 6.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KDO18316.1 - 0.058 11.5 0.1 0.69 8.0 0.0 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.22 KDO18317.1 - 3.4e-28 97.3 0.0 5.3e-10 39.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO18317.1 - 8.2e-06 25.6 0.0 0.034 14.0 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif CDC45 PF02724.14 KDO18317.1 - 8.9 4.5 11.4 12 4.1 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 KDO18318.1 - 7e-14 51.7 0.0 3.2e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO18318.1 - 2.2e-09 37.1 0.0 6.6e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 KDO18319.1 - 1.4e-11 43.9 12.8 2.9e-07 30.1 3.8 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO18319.1 - 9.3e-10 38.6 7.3 1.2e-05 25.5 1.7 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO18319.1 - 2.7e-09 36.3 1.4 0.00062 19.6 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KDO18319.1 - 1.3e-05 24.8 0.2 1.7e-05 24.4 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KDO18319.1 - 0.00066 19.9 2.1 1.7 9.5 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat AA_permease_2 PF13520.6 KDO18320.1 - 8.8e-39 133.5 41.2 9.2e-38 130.2 41.2 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO18320.1 - 1.7e-32 112.6 35.3 2.6e-32 112.1 35.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KDO18320.1 - 1e-07 31.9 1.6 1e-07 31.9 1.6 3.5 5 0 0 5 5 5 1 C-terminus of AA_permease AA_permease_2 PF13520.6 KDO18321.1 - 2.6e-39 135.3 37.4 2.6e-39 135.3 37.4 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KDO18321.1 - 7.9e-28 97.3 35.9 1.2e-27 96.7 35.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KDO18321.1 - 3.2e-13 49.5 1.1 3.2e-13 49.5 1.1 3.1 3 0 0 3 3 3 1 C-terminus of AA_permease EptA_B_N PF08019.12 KDO18321.1 - 0.3 11.0 13.4 3.7 7.4 5.6 2.8 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB AA_permease_2 PF13520.6 KDO18322.1 - 2.3e-45 155.2 39.3 2.4e-45 155.1 38.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO18322.1 - 5.9e-34 117.5 36.0 8.3e-34 117.0 36.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KDO18322.1 - 1.3e-10 41.2 1.2 1.3e-10 41.2 1.2 4.5 5 0 0 5 5 5 1 C-terminus of AA_permease Pyridoxal_deC PF00282.19 KDO18323.1 - 5.1e-32 111.0 0.0 2.4e-28 98.9 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KDO18323.1 - 7.5e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KDO18323.1 - 0.031 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II BT1 PF03092.16 KDO18324.1 - 7.5e-12 44.2 1.1 8.1e-12 44.1 1.1 1.0 1 0 0 1 1 1 1 BT1 family Peptidase_U4 PF03419.13 KDO18324.1 - 0.0082 15.5 3.3 0.0099 15.2 3.3 1.0 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Arb1 PF09692.10 KDO18324.1 - 0.22 10.7 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Ricin_B_lectin PF00652.22 KDO18325.1 - 5.2e-06 26.7 1.1 7.7e-06 26.2 1.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO18325.1 - 0.00027 21.6 1.2 0.0029 18.3 0.5 2.5 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KDO18327.1 - 7.8e-05 22.9 0.7 0.00011 22.4 0.7 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO18327.1 - 0.0011 19.6 0.7 0.0029 18.3 0.7 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like GSP_synth PF03738.14 KDO18329.1 - 1.1e-16 60.9 0.0 1.2e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp GSP_synth PF03738.14 KDO18330.1 - 1.6e-30 106.5 0.0 2.2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 KDO18330.1 - 3e-07 30.9 0.0 8.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 CHAP domain GSP_synth PF03738.14 KDO18332.1 - 7.6e-63 212.9 0.0 1.4e-62 212.1 0.0 1.4 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 KDO18332.1 - 1.6e-08 35.0 0.0 3.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 CHAP domain Mpv17_PMP22 PF04117.12 KDO18333.1 - 6.5e-07 29.5 0.7 1.2e-06 28.7 0.1 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ank_2 PF12796.7 KDO18334.1 - 4.2e-37 126.6 10.1 1.4e-15 57.6 2.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18334.1 - 4.3e-30 103.7 4.2 1.1e-07 32.2 0.0 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO18334.1 - 3.4e-28 96.8 15.3 0.00038 20.8 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KDO18334.1 - 4.9e-28 94.1 5.8 0.0022 18.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KDO18334.1 - 4.2e-26 90.7 17.6 7.4e-10 38.9 0.7 6.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) DZR PF12773.7 KDO18334.1 - 0.00075 19.5 6.3 0.0014 18.6 6.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon Cytochrom_c3_2 PF14537.6 KDO18334.1 - 0.016 15.6 0.8 0.033 14.7 0.8 1.5 1 0 0 1 1 1 0 Cytochrome c3 DUF4799 PF16056.5 KDO18334.1 - 2.7 7.1 7.0 5 6.2 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4799) Ank_2 PF12796.7 KDO18335.1 - 5.4e-43 145.5 8.7 1.4e-16 60.9 0.4 5.1 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18335.1 - 8.7e-40 134.6 4.5 3.7e-11 43.3 0.0 8.3 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18335.1 - 5.8e-35 115.4 7.4 0.00019 21.6 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KDO18335.1 - 8.1e-34 115.3 18.5 9.9e-08 32.1 0.3 9.0 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO18335.1 - 2.9e-27 93.9 25.3 0.00024 21.4 0.3 10.1 11 0 0 11 11 11 6 Ankyrin repeat DUF2807 PF10988.8 KDO18336.1 - 2.1e-16 60.2 4.3 1.5e-10 41.2 2.3 2.3 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain DUF2807 PF10988.8 KDO18337.1 - 0.0026 17.6 1.3 0.14 12.0 0.6 2.2 2 0 0 2 2 2 2 Putative auto-transporter adhesin, head GIN domain PAN_4 PF14295.6 KDO18338.1 - 3.1e-13 49.4 13.6 3.4e-07 30.0 1.1 2.9 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 KDO18338.1 - 2.5e-09 37.0 6.0 0.00017 21.5 0.3 3.6 3 1 1 4 4 4 2 PAN domain PDR_assoc PF08370.11 KDO18339.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Plant PDR ABC transporter associated MORN PF02493.20 KDO18341.1 - 3.9e-11 42.1 32.1 0.0084 16.0 0.1 9.8 10 0 0 10 10 10 6 MORN repeat Ank_2 PF12796.7 KDO18343.1 - 1.7e-15 57.4 1.6 1.7e-08 34.9 0.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO18343.1 - 1.3e-08 34.4 5.4 0.00039 20.7 0.2 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KDO18343.1 - 1.2e-07 32.1 1.9 0.065 13.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO18343.1 - 5.5e-07 29.7 8.4 0.0016 18.8 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO18343.1 - 9.7e-07 29.0 4.9 0.0093 16.3 0.2 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO18344.1 - 2.6e-53 178.5 22.2 1.5e-11 44.7 3.3 7.5 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18344.1 - 1.8e-42 143.2 19.4 8.1e-09 35.9 0.1 10.2 7 2 2 9 9 9 7 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO18344.1 - 3.9e-39 134.6 0.0 6.3e-37 127.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Ank_3 PF13606.6 KDO18344.1 - 4.9e-38 124.8 20.6 0.0013 19.0 0.0 13.3 14 0 0 14 14 14 10 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO18344.1 - 5.1e-33 114.4 0.0 1.7e-30 106.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Ank PF00023.30 KDO18344.1 - 2.1e-29 100.7 30.5 4.1e-05 23.8 0.0 10.9 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KDO18344.1 - 1.8e-25 88.6 23.3 2.2e-06 27.8 1.4 9.5 5 3 4 10 10 10 7 Ankyrin repeats (many copies) Kinase-like PF14531.6 KDO18344.1 - 7.7e-06 25.4 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO18344.1 - 0.035 13.5 0.0 0.37 10.1 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_U32 PF01136.19 KDO18345.1 - 0.2 10.8 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 Bac_surface_Ag PF01103.23 KDO18346.1 - 3.3e-29 102.4 0.0 4.2e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KDO18346.1 - 0.0072 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Surface antigen variable number repeat ShlB PF03865.13 KDO18346.1 - 0.069 12.6 0.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_1 PF08478.10 KDO18346.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 POTRA domain, FtsQ-type TRAM_LAG1_CLN8 PF03798.16 KDO18347.1 - 1.8e-31 109.4 22.6 2.7e-31 108.9 22.6 1.3 1 0 0 1 1 1 1 TLC domain Ank_4 PF13637.6 KDO18348.1 - 2.4e-14 53.5 0.6 6.6e-06 26.6 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO18348.1 - 3.6e-14 53.1 3.5 1.9e-12 47.6 0.8 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO18348.1 - 1.6e-12 46.4 0.1 0.00065 20.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO18348.1 - 1.6e-12 47.3 0.8 0.00023 21.4 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO18348.1 - 1.2e-11 44.5 2.6 9.5e-05 22.7 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat TRAM_LAG1_CLN8 PF03798.16 KDO18350.1 - 4.9e-34 117.8 15.7 7.5e-34 117.2 15.7 1.3 1 0 0 1 1 1 1 TLC domain Glu_dehyd_C PF16912.5 KDO18351.1 - 0.02 14.4 0.1 0.02 14.4 0.1 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NOA36 PF06524.12 KDO18352.1 - 9.7 5.4 12.8 10 5.3 12.8 1.0 1 0 0 1 1 1 0 NOA36 protein OppC_N PF12911.7 KDO18353.1 - 0.098 12.6 2.1 0.14 12.1 0.1 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C UvsY PF11056.8 KDO18355.1 - 0.046 14.1 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF1016_N PF17761.1 KDO18355.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain Sugar_tr PF00083.24 KDO18359.1 - 3.4e-27 95.4 5.6 4.6e-27 95.0 5.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO18359.1 - 8.3e-19 67.7 10.8 9.9e-19 67.5 10.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KDO18359.1 - 0.016 13.8 8.4 0.0055 15.3 4.9 1.8 1 1 1 2 2 2 0 MFS/sugar transport protein AbiJ_NTD5 PF18865.1 KDO18359.1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 VIT1 PF01988.19 KDO18359.1 - 6.1 6.6 8.5 0.86 9.4 1.8 2.3 2 1 0 2 2 2 0 VIT family ABC_trans_N PF14510.6 KDO18360.1 - 0.15 12.7 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC-transporter N-terminal Disintegrin PF00200.23 KDO18363.1 - 3.9e-23 82.0 83.7 8.8e-05 23.2 3.9 7.9 5 4 1 6 6 6 6 Disintegrin DUF4246 PF14033.6 KDO18364.1 - 2.1e-36 126.0 0.0 2.8e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PfkB PF00294.24 KDO18366.1 - 3.7e-41 141.4 0.0 4.8e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase LRR_8 PF13855.6 KDO18369.1 - 6.3e-18 64.3 21.7 0.0014 18.3 0.1 6.9 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KDO18369.1 - 6.2e-14 51.9 30.3 0.00058 20.2 1.1 7.8 4 1 3 8 8 8 5 Leucine Rich repeats (2 copies) START PF01852.19 KDO18369.1 - 3.2e-06 26.7 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO18369.1 - 2.3e-05 24.4 12.3 5.9e-05 23.1 12.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18369.1 - 0.0013 18.9 6.1 0.0023 18.1 6.1 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger LRR_1 PF00560.33 KDO18369.1 - 0.0045 17.3 13.5 3.8 8.4 0.1 7.1 6 1 1 7 7 7 2 Leucine Rich Repeat Tom6 PF17112.5 KDO18369.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal LRR_6 PF13516.6 KDO18369.1 - 0.1 12.7 29.5 0.53 10.5 0.1 7.8 11 0 0 11 11 11 0 Leucine Rich repeat FNIP PF05725.12 KDO18369.1 - 0.52 10.5 14.6 4.7 7.5 0.4 4.5 5 0 0 5 5 5 0 FNIP Repeat GST_C_5 PF16865.5 KDO18371.1 - 7.9e-12 45.7 0.1 2.5e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO18371.1 - 1.8e-10 41.1 0.0 4.6e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO18371.1 - 1.4e-09 37.8 0.2 2.7e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO18371.1 - 1.1e-08 35.3 0.0 3.9e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO18371.1 - 2.6e-07 30.8 0.0 4.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO18371.1 - 3.1e-06 27.3 0.1 5.2e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO18371.1 - 0.0023 18.1 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KDO18372.1 - 4e-14 53.1 0.1 1.1e-13 51.7 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO18372.1 - 6.6e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO18372.1 - 7.3e-08 32.6 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO18372.1 - 2.2e-07 30.8 0.6 4.1e-07 29.9 0.6 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO18372.1 - 1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO18372.1 - 8.4e-06 25.9 0.1 1.5e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO18372.1 - 0.024 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HMGL-like PF00682.19 KDO18374.1 - 4.6e-22 78.8 0.0 5.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Ribosomal_L31e PF01198.19 KDO18376.1 - 0.056 13.7 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L31e LRR_4 PF12799.7 KDO18377.1 - 5.4e-05 23.5 0.1 0.053 14.0 0.1 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO18377.1 - 0.0019 18.1 6.5 0.047 13.8 0.1 4.8 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.6 KDO18377.1 - 0.31 10.8 2.6 54 3.7 0.1 4.2 4 1 0 4 4 4 0 Leucine rich repeat ABC_membrane PF00664.23 KDO18378.1 - 1.3e-17 64.3 7.6 1.9e-17 63.8 7.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Disintegrin PF00200.23 KDO18382.1 - 1.6e-05 25.6 12.9 0.00015 22.4 3.8 3.6 2 1 1 3 3 3 3 Disintegrin Bax1-I PF01027.20 KDO18383.1 - 5.6e-32 111.3 28.0 6.8e-32 111.0 28.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FAD_binding_3 PF01494.19 KDO18384.1 - 2.2e-30 106.1 0.0 3.1e-20 72.7 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Sugar_tr PF00083.24 KDO18385.1 - 7.2e-107 358.1 21.4 8.1e-107 357.9 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO18385.1 - 3.7e-29 101.7 31.0 8.5e-20 71.0 8.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO18385.1 - 0.00019 20.0 0.9 0.00031 19.3 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KDO18385.1 - 0.0069 15.0 3.5 0.0069 15.0 3.5 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein Ribonucleas_3_3 PF14622.6 KDO18386.1 - 5.8e-35 120.2 0.0 1.3e-17 64.2 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KDO18386.1 - 5.6e-34 116.9 0.7 2.6e-15 56.9 0.1 3.5 2 1 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 KDO18386.1 - 0.002 18.8 0.0 0.0063 17.2 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif Sacchrp_dh_C PF16653.5 KDO18387.1 - 6.3e-84 282.2 0.0 8.1e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KDO18387.1 - 4e-16 59.4 0.1 6.1e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KDO18387.1 - 0.055 13.9 0.2 0.14 12.6 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KDO18387.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Atg14 PF10186.9 KDO18388.1 - 6.2e-11 41.9 1.3 1e-10 41.3 1.3 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 KDO18388.1 - 0.59 9.3 5.7 0.98 8.6 5.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ABC_tran_Xtn PF12848.7 KDO18388.1 - 4 7.5 12.0 7.4 6.7 12.0 1.4 1 0 0 1 1 1 0 ABC transporter Snf7 PF03357.21 KDO18388.1 - 6.6 6.3 12.6 12 5.5 12.6 1.3 1 0 0 1 1 1 0 Snf7 Cadherin_C_2 PF16492.5 KDO18391.1 - 0.022 15.5 0.0 0.048 14.4 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4448 PF14610.6 KDO18391.1 - 0.052 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ISK_Channel PF02060.15 KDO18391.1 - 0.092 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Gram_pos_anchor PF00746.21 KDO18391.1 - 0.16 11.9 1.3 0.25 11.3 1.3 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif FYVE PF01363.21 KDO18394.1 - 1.1e-07 31.9 10.5 1.1e-07 31.9 10.5 2.2 2 0 0 2 2 2 1 FYVE zinc finger zinc_ribbon_5 PF13719.6 KDO18394.1 - 0.0016 18.2 4.9 0.031 14.0 5.2 2.6 1 1 1 2 2 2 1 zinc-ribbon domain FYVE_2 PF02318.16 KDO18394.1 - 0.09 13.0 9.7 0.18 12.0 9.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KDO18395.1 - 3.4e-05 23.9 13.9 6.5e-05 23.0 13.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger SH3-RhoG_link PF16609.5 KDO18395.1 - 0.0013 18.5 0.1 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region FYVE_2 PF02318.16 KDO18395.1 - 0.0053 17.0 8.2 0.0081 16.4 8.2 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_2 PF14445.6 KDO18395.1 - 0.057 13.6 1.3 0.057 13.6 1.3 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FYVE PF01363.21 KDO18396.1 - 0.00019 21.5 12.3 0.00065 19.8 12.3 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18396.1 - 0.00097 19.3 9.3 0.0024 18.1 9.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger START PF01852.19 KDO18397.1 - 2.8e-05 23.6 0.1 4.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO18397.1 - 0.00046 20.3 15.4 0.0015 18.6 15.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18397.1 - 0.086 13.1 11.7 0.12 12.6 10.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger IRK_C PF17655.1 KDO18398.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 KDO18398.1 - 0.00013 21.9 2.6 0.00013 21.9 2.6 2.2 1 1 1 2 2 2 2 Ion channel IRK PF01007.20 KDO18398.1 - 1.7 8.4 7.4 16 5.3 7.4 2.1 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 KDO18399.1 - 6.3e-09 35.7 0.1 1.6e-08 34.3 0.0 1.7 2 1 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 KDO18399.1 - 3.6e-07 30.0 2.8 8e-07 28.9 2.8 1.7 1 0 0 1 1 1 1 Ion channel IRK PF01007.20 KDO18399.1 - 0.0017 18.2 4.2 0.014 15.2 4.2 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ank_2 PF12796.7 KDO18402.1 - 6.5e-176 571.4 92.7 5.8e-18 65.3 0.2 14.0 1 1 14 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.30 KDO18402.1 - 3.5e-132 425.7 107.0 1.4e-05 25.3 0.4 28.2 28 0 0 28 28 28 25 Ankyrin repeat Ank_5 PF13857.6 KDO18402.1 - 5.9e-117 380.2 85.4 6.2e-10 39.1 0.4 21.4 6 6 15 22 22 22 22 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO18402.1 - 4.1e-114 371.6 67.1 8e-09 35.9 0.0 22.1 5 4 20 25 25 25 24 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18402.1 - 1.3e-102 323.3 54.8 0.00024 21.3 0.0 28.7 29 0 0 29 29 28 22 Ankyrin repeat Mur_ligase PF01225.25 KDO18402.1 - 4.7e-09 36.4 9.2 2 8.8 0.0 8.3 8 2 0 8 8 8 3 Mur ligase family, catalytic domain BiPBP_C PF06832.12 KDO18402.1 - 8.4e-07 28.9 8.9 1.9 8.6 0.0 9.4 9 3 2 12 12 11 1 Penicillin-Binding Protein C-terminus Family NUDIX PF00293.28 KDO18402.1 - 5.8e-06 26.4 0.4 0.00024 21.1 0.4 3.2 1 1 0 1 1 1 1 NUDIX domain DUF3107 PF11305.8 KDO18402.1 - 0.00019 21.6 7.6 8.3 6.7 0.0 9.2 8 3 3 11 11 11 1 Protein of unknown function (DUF3107) EccE PF11203.8 KDO18402.1 - 0.00028 21.2 32.3 0.4 11.0 1.3 6.5 7 1 0 7 7 6 4 Putative type VII ESX secretion system translocon, EccE Il2rg PF15874.5 KDO18402.1 - 0.0033 17.6 12.4 24 5.3 0.0 8.8 6 3 4 10 10 10 0 Putative Interleukin 2 receptor, gamma chain Nitro_FeMo-Co PF02579.17 KDO18402.1 - 0.0044 17.3 10.6 11 6.5 0.1 6.6 7 1 1 8 8 8 1 Dinitrogenase iron-molybdenum cofactor Glyoxalase_6 PF18029.1 KDO18402.1 - 0.012 16.4 17.7 18 6.1 0.1 6.9 6 0 0 6 6 6 0 Glyoxalase-like domain HEM4 PF02602.15 KDO18402.1 - 0.02 14.2 7.1 59 2.9 0.0 6.9 8 1 1 9 9 9 0 Uroporphyrinogen-III synthase HemD DUF99 PF01949.16 KDO18402.1 - 0.77 9.1 5.0 3.7 6.9 0.1 3.3 4 0 0 4 4 3 0 Protein of unknown function DUF99 Erythro-docking PF09277.11 KDO18402.1 - 1.3 9.0 20.0 14 5.7 0.4 8.2 9 0 0 9 9 9 0 Erythronolide synthase, docking Ank_2 PF12796.7 KDO18403.1 - 1.3e-42 144.3 12.2 5.2e-12 46.2 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KDO18403.1 - 1.9e-41 138.7 22.5 3e-06 27.4 0.4 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KDO18403.1 - 4.3e-36 122.5 14.5 2.7e-10 40.3 1.4 6.3 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18403.1 - 2.8e-29 97.9 3.3 0.0006 20.1 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KDO18403.1 - 2.2e-27 95.1 9.0 5.5e-07 30.0 0.2 6.9 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Mur_ligase PF01225.25 KDO18403.1 - 0.0026 18.1 2.8 2.5 8.5 0.1 4.1 3 1 1 5 5 5 1 Mur ligase family, catalytic domain Il2rg PF15874.5 KDO18403.1 - 0.0032 17.7 3.6 11 6.3 0.1 4.2 4 1 0 4 4 4 1 Putative Interleukin 2 receptor, gamma chain HEM4 PF02602.15 KDO18403.1 - 0.0036 16.7 0.4 3.1 7.1 0.0 3.7 1 1 0 2 2 2 1 Uroporphyrinogen-III synthase HemD DUF3107 PF11305.8 KDO18403.1 - 0.0076 16.5 1.9 20 5.5 0.0 4.5 3 2 1 4 4 4 0 Protein of unknown function (DUF3107) EccE PF11203.8 KDO18403.1 - 0.098 13.0 1.0 13 6.2 0.2 3.2 1 1 2 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Erythro-docking PF09277.11 KDO18403.1 - 0.13 12.2 1.9 24 4.9 0.1 4.3 4 1 1 5 5 5 0 Erythronolide synthase, docking Nitro_FeMo-Co PF02579.17 KDO18403.1 - 0.33 11.3 1.2 15 6.0 0.0 2.9 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor ORF_2_N PF18492.1 KDO18403.1 - 0.89 9.8 10.9 3.3 7.9 1.2 3.8 3 1 1 4 4 4 0 Open reading frame 2 N-terminal domain Ribosomal_L28e PF01778.17 KDO18405.1 - 9.7e-39 132.7 1.7 9.7e-39 132.7 1.7 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KDO18405.1 - 6.8e-24 84.4 2.9 6.8e-24 84.4 2.9 1.7 2 0 0 2 2 2 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.15 KDO18405.1 - 0.1 12.2 2.2 0.11 12.1 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1151 PF06625.11 KDO18405.1 - 0.77 9.7 10.7 1.1 9.3 10.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) PQQ_3 PF13570.6 KDO18406.1 - 0.0011 19.4 0.9 0.12 12.9 0.0 3.6 4 0 0 4 4 4 1 PQQ-like domain Methyltr_RsmB-F PF01189.17 KDO18409.1 - 7.4e-73 244.5 0.0 1.5e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KDO18409.1 - 6.3e-08 33.0 0.0 1.9e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 KDO18409.1 - 2.8e-05 24.0 0.0 6.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KDO18409.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KDO18409.1 - 0.00021 22.0 0.2 0.00073 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KDO18409.1 - 0.00097 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KDO18409.1 - 0.0022 17.4 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SDA1 PF05285.12 KDO18409.1 - 3.8 6.8 69.8 0.19 11.1 30.2 2.5 2 0 0 2 2 2 0 SDA1 RRM_1 PF00076.22 KDO18410.1 - 0.14 12.0 1.0 0.29 11.0 0.0 2.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 KDO18410.1 - 0.24 10.7 25.3 0.31 10.3 25.3 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KDO18410.1 - 0.84 9.0 27.2 1.1 8.6 27.2 1.3 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.13 KDO18410.1 - 1.1 8.3 14.0 1.2 8.1 14.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.12 KDO18410.1 - 9.1 4.3 28.4 12 4.0 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.7 KDO18413.1 - 2.6e-20 72.8 0.0 1.8e-18 66.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO18413.1 - 1.9e-18 66.0 0.0 1e-07 32.0 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO18413.1 - 7.1e-18 64.4 0.0 5.8e-06 26.5 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO18413.1 - 1.2e-17 64.0 0.0 7.8e-08 32.7 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18413.1 - 1e-16 59.3 0.0 2.4e-06 27.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Pkinase PF00069.25 KDO18414.1 - 6.6e-34 117.5 0.0 1.5e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18414.1 - 5.5e-33 114.3 0.0 9.6e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KDO18414.1 - 4.8e-22 78.3 3.2 8.3e-10 39.1 0.3 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18414.1 - 2.9e-17 62.8 0.7 4e-05 24.1 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO18414.1 - 1.8e-15 56.6 7.6 1.3e-05 25.4 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KDO18414.1 - 5e-14 51.0 0.5 0.0032 17.8 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KDO18414.1 - 2.1e-08 34.3 4.2 7.9e-05 22.9 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) DZR PF12773.7 KDO18414.1 - 0.37 10.8 8.8 1 9.5 8.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KDO18414.1 - 0.53 11.1 4.8 1.3 9.8 4.8 1.7 1 0 0 1 1 1 0 zinc-ribbon family Cytochrom_c3_2 PF14537.6 KDO18414.1 - 2.9 8.4 8.1 8 7.0 8.1 1.8 1 0 0 1 1 1 0 Cytochrome c3 PH PF00169.29 KDO18417.1 - 1.9e-07 31.6 0.0 2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO18417.1 - 0.0022 18.2 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KDO18418.1 - 3.5e-16 59.6 0.0 4.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO18418.1 - 2.2e-07 31.2 0.5 3.9e-07 30.4 0.5 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO18418.1 - 0.0012 19.0 0.5 0.0081 16.4 0.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO18418.1 - 0.0037 17.6 0.0 0.0077 16.6 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO18418.1 - 0.011 15.8 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KDO18419.1 - 5.6e-13 49.3 0.0 7.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO18419.1 - 2e-06 28.2 0.0 7.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO18419.1 - 8.7e-05 22.6 0.0 0.00062 19.8 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO18419.1 - 0.00013 22.1 0.1 0.0029 17.9 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO18419.1 - 0.0043 17.4 0.2 0.2 12.0 0.0 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KDO18420.1 - 3.2e-12 46.9 0.0 4.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO18420.1 - 0.00065 20.1 0.6 0.0015 18.9 0.6 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO18420.1 - 0.0041 17.2 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.6 KDO18420.1 - 0.0052 17.0 1.0 0.087 13.1 1.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO18420.1 - 0.009 16.4 0.1 0.068 13.5 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain HGTP_anticodon PF03129.20 KDO18422.1 - 3.5e-20 71.9 0.0 4.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain FAP PF07174.11 KDO18424.1 - 2 7.8 22.1 2.9 7.3 22.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) AA_kinase PF00696.28 KDO18425.1 - 4.8e-17 62.4 0.1 6.7e-17 61.9 0.1 1.3 1 1 0 1 1 1 1 Amino acid kinase family Ank_2 PF12796.7 KDO18428.1 - 1.5e-33 115.2 5.5 6.1e-12 46.0 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18428.1 - 1.1e-24 86.4 11.9 3.8e-09 36.9 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18428.1 - 3.4e-23 81.4 5.1 3.7e-11 43.1 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18428.1 - 5.9e-17 60.0 2.2 4.9e-06 26.5 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KDO18428.1 - 2e-16 59.6 8.8 6.5e-08 32.7 0.8 4.5 5 0 0 5 5 4 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 KDO18428.1 - 1.4e-09 37.7 17.7 1.8e-09 37.3 9.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO18428.1 - 0.0014 18.4 11.7 0.0014 18.4 11.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO18428.1 - 0.0027 17.6 11.9 0.0027 17.6 11.9 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KDO18428.1 - 0.013 15.5 17.5 11 6.1 17.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 KDO18428.1 - 0.017 14.4 1.3 0.017 14.4 1.3 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 KDO18428.1 - 0.12 11.8 6.1 5.3 6.6 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Gin PF10764.9 KDO18428.1 - 0.67 10.0 7.2 2.1 8.4 7.2 1.9 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DUF2039 PF10217.9 KDO18428.1 - 1.2 9.5 12.3 5.1 7.5 12.3 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 KDO18428.1 - 4.6 7.1 12.1 4.9 7.0 2.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain MatE PF01554.18 KDO18429.1 - 1.5e-10 41.0 1.7 7.1e-10 38.8 0.4 1.9 2 0 0 2 2 2 1 MatE DUF4191 PF13829.6 KDO18429.1 - 0.2 11.0 0.6 0.26 10.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) MatE PF01554.18 KDO18430.1 - 4.2e-35 120.8 30.9 2.2e-24 86.0 14.9 2.1 2 0 0 2 2 2 2 MatE MatE PF01554.18 KDO18431.1 - 3.2e-48 163.4 29.5 2.1e-24 86.0 10.3 2.1 2 0 0 2 2 2 2 MatE MatE PF01554.18 KDO18432.1 - 4.6e-45 153.2 34.8 2.1e-23 82.8 9.0 2.2 2 0 0 2 2 2 2 MatE tRNA_m1G_MT PF01746.21 KDO18434.1 - 1.6e-28 99.8 0.0 2.3e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF3108 PF11306.8 KDO18434.1 - 0.076 13.0 0.3 0.56 10.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3108) DUF5102 PF17104.5 KDO18434.1 - 0.19 11.7 4.0 0.24 11.4 3.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Vta1 PF04652.16 KDO18435.1 - 4.5e-45 153.2 0.3 6.2e-45 152.7 0.3 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KDO18435.1 - 0.00027 20.5 0.6 0.00027 20.5 0.6 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain MatE PF01554.18 KDO18436.1 - 3.6e-23 82.0 7.5 3.6e-23 82.0 7.5 1.8 2 0 0 2 2 2 1 MatE Ank_2 PF12796.7 KDO18437.1 - 7.3e-10 39.3 0.2 0.00018 22.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO18437.1 - 0.019 15.4 1.5 0.86 10.2 0.1 3.0 2 1 1 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 KDO18437.1 - 0.05 14.2 0.5 0.21 12.2 0.5 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18437.1 - 0.067 13.8 0.7 19 6.2 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Zn_Tnp_IS91 PF14319.6 KDO18437.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain AhpC-TSA PF00578.21 KDO18439.1 - 2.1e-38 131.0 0.0 4.1e-38 130.1 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KDO18439.1 - 2.2e-16 59.9 0.0 3.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KDO18439.1 - 2.3e-13 49.8 0.1 4.1e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KDO18439.1 - 0.028 14.3 0.1 0.064 13.2 0.0 1.7 2 1 0 2 2 2 0 SCO1/SenC Lung_7-TM_R PF06814.13 KDO18440.1 - 2.6e-49 168.1 14.2 3.2e-49 167.8 14.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KDO18440.1 - 0.00071 19.1 16.6 0.0014 18.0 16.4 1.6 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Peptidase_C25_C PF03785.14 KDO18440.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain EF-hand_1 PF00036.32 KDO18441.1 - 1.5e-24 83.6 1.8 2.9e-05 23.3 0.0 5.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KDO18441.1 - 5.5e-20 71.6 3.6 3.6e-07 30.5 0.5 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO18441.1 - 5.5e-19 66.4 4.0 0.00066 19.4 0.4 5.9 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 KDO18441.1 - 5.3e-13 47.8 1.9 9.4e-05 21.7 0.0 5.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KDO18441.1 - 2.9e-09 36.6 4.1 0.049 13.5 0.0 4.9 4 1 1 5 5 5 4 EF-hand domain pair DUF5631 PF18645.1 KDO18441.1 - 0.15 12.5 0.4 0.47 10.9 0.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5631) Sun2_CC2 PF18580.1 KDO18441.1 - 0.64 10.3 4.7 13 6.1 0.1 3.1 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 DUF4381 PF14316.6 KDO18442.1 - 0.059 13.6 0.1 0.062 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PAN_4 PF14295.6 KDO18443.1 - 1.7e-10 40.7 11.1 3.4e-08 33.2 2.2 2.4 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 KDO18443.1 - 1.7e-07 31.1 0.5 1.7e-07 31.1 0.5 1.6 1 1 1 2 2 2 1 PAN domain SDF PF00375.18 KDO18444.1 - 2.4e-67 227.7 45.8 7e-67 226.1 45.8 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family NolB PF17398.2 KDO18444.1 - 0.088 13.2 2.5 0.17 12.3 2.5 1.4 1 0 0 1 1 1 0 Nodulation protein NolB DUF5409 PF17421.2 KDO18444.1 - 0.16 12.7 0.7 0.58 10.9 0.7 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5409) SDF PF00375.18 KDO18445.1 - 4.7e-71 239.9 39.8 2.7e-70 237.4 39.8 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO18446.1 - 8.8e-71 239.0 47.0 9.6e-70 235.6 47.0 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Pkinase PF00069.25 KDO18447.1 - 5.3e-06 26.0 0.1 5.8e-06 25.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18447.1 - 0.0031 16.8 0.1 0.0033 16.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KDO18447.1 - 0.012 15.8 0.2 0.013 15.7 0.2 1.1 1 0 0 1 1 1 0 ABC1 family DUF4533 PF15047.6 KDO18447.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) PUF PF00806.19 KDO18452.1 - 0.028 14.1 0.1 0.081 12.7 0.1 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat UbiA PF01040.18 KDO18455.1 - 4.9e-51 173.4 16.3 6e-51 173.2 16.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DNA_pol_E_B PF04042.16 KDO18457.1 - 2.3e-32 112.1 0.5 3.1e-32 111.6 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B zf-3CxxC_2 PF17180.4 KDO18457.1 - 2.8e-09 37.6 4.7 2.8e-09 37.6 4.7 1.7 2 0 0 2 2 2 1 Zinc-binding domain UPF0515 PF15135.6 KDO18457.1 - 0.024 14.0 2.8 0.054 12.9 2.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 KDO18457.1 - 1.6 9.2 10.6 76 3.9 10.6 2.8 1 1 0 1 1 1 0 Zinc-binding domain Lipase_GDSL_2 PF13472.6 KDO18459.1 - 3.5e-27 96.0 0.0 4.4e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO18459.1 - 7.4e-17 62.0 0.0 1.3e-16 61.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KDO18460.1 - 1.8e-27 96.9 0.1 2.3e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO18460.1 - 6.5e-15 55.6 0.0 2.6e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KDO18460.1 - 0.028 14.5 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Mesd PF10185.9 KDO18461.1 - 2.7e-08 33.9 1.8 4.4e-08 33.2 1.8 1.3 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF3381 PF11861.8 KDO18461.1 - 0.92 9.3 11.4 0.18 11.6 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) AOX PF01786.17 KDO18463.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase EGF_2 PF07974.13 KDO18463.1 - 0.035 14.5 7.6 0.085 13.2 7.6 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3522 PF12036.8 KDO18464.1 - 0.00019 21.8 1.2 0.00019 21.8 1.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) DUF4131 PF13567.6 KDO18464.1 - 0.25 11.0 1.1 0.29 10.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pox_LP_H2 PF03356.15 KDO18465.1 - 0.0075 16.2 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Viral late protein H2 CTV_P6 PF06706.11 KDO18465.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein MFS_1_like PF12832.7 KDO18466.1 - 2e-60 204.7 24.1 3.7e-60 203.8 24.1 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO18466.1 - 3.8e-18 65.5 37.6 4.1e-11 42.4 9.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO18466.1 - 8e-11 41.5 21.3 1e-10 41.2 21.3 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO18466.1 - 1.1e-08 34.3 16.1 2.1e-07 30.1 16.1 2.4 1 1 0 1 1 1 1 LacY proton/sugar symporter Pkinase PF00069.25 KDO18467.1 - 1.8e-58 198.0 0.0 2.7e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO18467.1 - 4.6e-50 167.6 0.3 1e-17 63.9 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO18467.1 - 1.5e-29 103.1 0.0 2.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L18_c PF14204.6 KDO18467.1 - 0.038 14.9 0.1 0.073 14.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region PDZ PF00595.24 KDO18469.1 - 2.8e-08 34.0 0.0 3.1e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO18469.1 - 2.4e-07 30.5 0.0 3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Na_H_Exchanger PF00999.21 KDO18470.1 - 8.5e-10 38.0 8.2 9.3e-10 37.8 8.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Herpes_BLLF1 PF05109.13 KDO18470.1 - 0.27 9.1 0.0 0.27 9.1 0.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) adh_short PF00106.25 KDO18472.1 - 2.2e-22 79.5 0.4 5e-15 55.5 0.0 2.4 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO18472.1 - 1.2e-16 61.0 0.8 1.7e-14 54.0 0.8 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KDO18472.1 - 0.00039 20.5 0.1 0.00068 19.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KDO18472.1 - 0.085 12.7 0.3 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 KDO18473.1 - 5.3e-42 143.9 0.0 7.5e-42 143.4 0.0 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 SPT6_acidic PF14632.6 KDO18473.1 - 0.048 14.3 6.0 0.12 12.9 6.0 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PBP1_TM PF14812.6 KDO18473.1 - 9 6.7 8.0 18 5.8 8.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spc7 PF08317.11 KDO18474.1 - 0.0028 16.6 6.9 0.0028 16.6 6.9 5.5 2 2 2 5 5 5 2 Spc7 kinetochore protein bZIP_1 PF00170.21 KDO18474.1 - 0.007 16.4 47.1 1.9 8.6 0.2 9.3 7 1 1 8 8 8 3 bZIP transcription factor ADIP PF11559.8 KDO18474.1 - 0.019 15.1 5.2 0.019 15.1 5.2 8.1 4 2 4 8 8 8 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 KDO18474.1 - 0.18 11.7 32.3 0.16 11.9 0.9 7.3 7 0 0 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor Filament PF00038.21 KDO18474.1 - 0.26 10.8 65.4 0.27 10.8 2.7 5.9 2 1 3 5 5 5 0 Intermediate filament protein Glyco_transf_18 PF15024.6 KDO18474.1 - 1.1 7.8 9.3 0.05 12.2 1.4 2.4 2 1 1 3 3 3 0 Glycosyltransferase family 18 Leu_zip PF15294.6 KDO18474.1 - 2.4 7.6 61.6 0.23 10.9 10.2 5.2 2 2 2 4 4 4 0 Leucine zipper CENP-F_leu_zip PF10473.9 KDO18474.1 - 2.9 7.9 82.6 0.26 11.3 11.3 6.8 3 3 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KDO18474.1 - 3.2 7.9 95.1 0.18 12.0 21.3 7.3 1 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KDO18474.1 - 5.3 7.5 73.4 1.3 9.4 9.6 5.3 1 1 4 5 5 5 0 Fez1 NPV_P10 PF05531.12 KDO18474.1 - 6.3 7.4 32.7 0.19 12.2 2.3 7.9 6 2 2 8 8 7 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 KDO18474.1 - 8.4 6.9 35.1 4.1 7.9 2.7 9.3 7 3 2 9 9 9 0 Lipoprotein leucine-zipper Viral_P18 PF04521.13 KDO18475.1 - 0.12 12.2 0.0 0.12 12.2 0.0 8.1 8 3 1 11 11 11 0 ssRNA positive strand viral 18kD cysteine rich protein Transthyretin PF00576.21 KDO18475.1 - 0.71 10.6 4.0 12 6.6 0.1 4.0 3 0 0 3 3 3 0 HIUase/Transthyretin family Surfac_D-trimer PF09006.11 KDO18475.1 - 0.77 9.7 2.9 14 5.6 0.1 4.8 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Kinesin PF00225.23 KDO18476.1 - 5.3e-17 61.7 0.0 3.3e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain UBN_AB PF14075.6 KDO18476.1 - 0.49 10.1 7.6 1.7 8.3 7.6 1.9 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Lipase_GDSL_2 PF13472.6 KDO18477.1 - 4.7e-27 95.5 0.4 6.2e-27 95.1 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO18477.1 - 3.8e-20 72.7 0.0 4.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KDO18477.1 - 0.0032 17.2 0.1 0.015 15.0 0.1 1.8 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX Mesd PF10185.9 KDO18478.1 - 1.1e-06 28.7 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor EGF_2 PF07974.13 KDO18480.1 - 8.1e-24 83.7 95.4 4.3e-07 30.2 3.7 8.6 8 0 0 8 8 8 6 EGF-like domain Laminin_EGF PF00053.24 KDO18480.1 - 4.8e-06 26.6 75.6 0.0016 18.5 4.2 6.9 6 1 0 6 6 6 6 Laminin EGF domain EGF PF00008.27 KDO18480.1 - 0.00013 22.2 87.4 0.0048 17.2 7.8 9.3 10 0 0 10 10 10 5 EGF-like domain hEGF PF12661.7 KDO18480.1 - 7.5 7.4 86.2 0.08 13.6 6.2 9.5 8 0 0 8 8 8 0 Human growth factor-like EGF PAP2_C PF14360.6 KDO18481.1 - 7.2e-12 45.7 6.7 7.2e-12 45.7 6.7 2.8 4 0 0 4 4 4 1 PAP2 superfamily C-terminal YrhC PF14143.6 KDO18481.1 - 1.7 8.8 7.8 0.15 12.2 1.1 2.3 2 0 0 2 2 2 0 YrhC-like protein ABC2_membrane PF01061.24 KDO18482.1 - 1.3e-31 109.7 24.7 1.3e-31 109.7 24.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KDO18482.1 - 8.3e-30 104.1 0.1 1.4e-29 103.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO18482.1 - 4.6e-12 46.4 0.1 2.7e-06 27.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO18482.1 - 9.8e-06 25.2 0.0 0.00041 19.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KDO18482.1 - 2.1e-05 24.2 0.1 5.7e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KDO18482.1 - 0.00016 21.3 0.1 0.00052 19.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO18482.1 - 0.0007 20.0 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KDO18482.1 - 0.0011 18.9 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KDO18482.1 - 0.0022 18.5 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO18482.1 - 0.0028 17.9 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDR_CDR PF06422.12 KDO18482.1 - 0.0072 16.2 0.2 0.0072 16.2 0.2 2.8 2 1 1 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KDO18482.1 - 0.0099 15.0 25.0 0.02 14.0 25.1 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein T2SSE PF00437.20 KDO18482.1 - 0.011 14.8 0.2 0.069 12.2 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein NACHT PF05729.12 KDO18482.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KDO18482.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KDO18482.1 - 0.03 13.0 0.1 0.72 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO18482.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 KDO18482.1 - 0.046 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 KDO18482.1 - 0.055 13.2 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KDO18482.1 - 0.06 13.0 0.1 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 KDO18482.1 - 0.081 13.4 0.0 0.28 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KDO18482.1 - 0.094 12.9 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Kelch_3 PF13415.6 KDO18483.1 - 0.016 15.5 0.2 0.055 13.8 0.1 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain FYVE PF01363.21 KDO18484.1 - 6e-06 26.3 16.3 6e-06 26.3 16.3 3.0 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18484.1 - 0.0028 17.8 11.3 0.0028 17.8 11.3 2.7 2 0 0 2 2 2 2 FYVE-type zinc finger HscB_4_cys PF18256.1 KDO18485.1 - 0.00012 21.7 1.9 0.2 11.5 0.3 2.8 2 0 0 2 2 2 2 Co-chaperone HscB tetracysteine metal binding motif Tenui_NS3 PF05310.12 KDO18485.1 - 0.0011 19.2 1.9 0.36 10.9 0.0 2.2 2 0 0 2 2 2 2 Tenuivirus movement protein zf-FCS PF06467.14 KDO18485.1 - 0.006 16.5 0.5 1.7 8.6 0.1 2.9 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.6 KDO18485.1 - 0.0075 15.6 4.7 0.81 9.2 0.3 3.0 3 0 0 3 3 3 2 zinc-ribbon domain zf_C2H2_13 PF18508.1 KDO18485.1 - 0.022 14.3 1.5 0.51 10.0 0.2 2.7 2 0 0 2 2 2 0 Zinc finger domain E7 PF00527.18 KDO18485.1 - 0.029 14.5 0.3 6.6 7.0 0.1 2.6 2 0 0 2 2 2 0 E7 protein, Early protein ROS_MUCR PF05443.11 KDO18485.1 - 0.068 13.2 1.2 12 5.9 0.2 3.1 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-CCHC PF00098.23 KDO18485.1 - 0.24 11.5 1.3 9.5 6.5 0.1 2.9 2 0 0 2 2 2 0 Zinc knuckle zf-BED PF02892.15 KDO18485.1 - 0.57 10.3 13.1 0.08 13.0 2.3 2.5 2 0 0 2 2 2 0 BED zinc finger RPA_interact_C PF14768.6 KDO18485.1 - 0.72 10.5 8.6 1.3 9.7 0.3 2.8 3 0 0 3 3 3 0 Replication protein A interacting C-terminal HypA PF01155.19 KDO18485.1 - 0.79 9.8 3.6 13 5.8 0.1 2.6 3 0 0 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sgf11 PF08209.11 KDO18485.1 - 1.5 8.5 10.1 5.4 6.7 0.1 4.0 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-B_box PF00643.24 KDO18485.1 - 3.6 7.8 7.8 5 7.4 0.1 2.8 3 0 0 3 3 2 0 B-box zinc finger DZR PF12773.7 KDO18485.1 - 5.2 7.2 8.7 6 7.0 0.3 3.0 3 0 0 3 3 3 0 Double zinc ribbon zf-C2HE PF16278.5 KDO18485.1 - 6.7 7.3 9.3 17 5.9 1.5 3.0 2 2 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2688 PF10892.8 KDO18485.1 - 7.4 6.1 9.6 37 3.9 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) Cyclin_N PF00134.23 KDO18486.1 - 2e-11 43.8 0.0 8.3e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF2306 PF10067.9 KDO18487.1 - 4.2e-14 53.0 10.2 4.2e-14 53.0 10.2 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) FAD_binding_6 PF00970.24 KDO18487.1 - 2.4e-09 37.4 0.0 5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KDO18487.1 - 0.0015 18.6 0.1 0.02 15.0 0.1 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF420 PF04238.12 KDO18487.1 - 0.02 15.2 12.1 0.041 14.2 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF420) NAD_binding_1 PF00175.21 KDO18487.1 - 0.033 14.9 0.0 0.6 10.8 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain SDF PF00375.18 KDO18488.1 - 9.4e-53 179.6 13.2 3.6e-52 177.7 13.2 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4586 PF15239.6 KDO18489.1 - 0.0023 18.2 0.3 0.12 12.6 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4586) LRR_6 PF13516.6 KDO18493.1 - 3.2e-10 39.2 17.6 0.0011 18.8 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 KDO18493.1 - 5.9e-06 26.5 3.2 0.026 14.9 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO18493.1 - 0.00027 20.6 0.3 0.00027 20.6 0.3 4.0 3 2 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KDO18493.1 - 0.003 17.9 3.3 2.3 9.1 0.0 5.2 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 KDO18493.1 - 0.004 16.7 0.2 0.47 9.9 0.1 2.4 2 0 0 2 2 2 2 Leucine-rich repeat Lipase_3 PF01764.25 KDO18494.1 - 1.6e-08 34.6 0.1 4.2e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 KDO18494.1 - 0.0035 17.2 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KDO18494.1 - 0.009 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KDO18494.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KDO18494.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KDO18494.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 KDO18494.1 - 0.026 14.4 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 KDO18494.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 KDO18494.1 - 0.047 14.3 0.0 0.051 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tricorn_C1 PF14684.6 KDO18494.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Tricorn protease C1 domain YbaB_DNA_bd PF02575.16 KDO18494.1 - 0.094 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DLH PF01738.18 KDO18494.1 - 0.095 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF676 PF05057.14 KDO18494.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Mnd1 PF03962.15 KDO18496.1 - 1.3e-24 86.2 0.1 3.2e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KDO18496.1 - 7.6e-17 61.2 2.3 1.2e-16 60.6 1.3 1.9 2 0 0 2 2 1 1 Leucine zipper with capping helix domain RPW8 PF05659.11 KDO18496.1 - 0.0025 17.5 0.7 0.0049 16.6 0.7 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 THOC7 PF05615.13 KDO18496.1 - 0.0038 17.5 4.3 0.0054 17.0 4.3 1.4 1 1 0 1 1 1 1 Tho complex subunit 7 Spc7 PF08317.11 KDO18496.1 - 0.017 14.0 7.9 0.28 10.0 8.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 KDO18496.1 - 0.025 13.5 4.5 0.033 13.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Baculo_F PF12259.8 KDO18496.1 - 0.038 12.5 0.9 0.043 12.3 0.9 1.1 1 0 0 1 1 1 0 Baculovirus F protein FapA PF03961.13 KDO18496.1 - 0.046 12.3 6.1 0.062 11.9 6.1 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KDO18496.1 - 0.049 13.0 3.6 0.061 12.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KDO18496.1 - 0.06 12.7 9.8 0.1 11.9 9.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Val_tRNA-synt_C PF10458.9 KDO18496.1 - 0.25 11.6 5.1 0.36 11.1 0.1 3.0 2 1 2 4 4 3 0 Valyl tRNA synthetase tRNA binding arm TPR_MLP1_2 PF07926.12 KDO18496.1 - 0.39 10.8 11.4 1.1 9.4 11.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KDO18496.1 - 0.41 11.2 10.2 0.79 10.2 10.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Viral_P18 PF04521.13 KDO18496.1 - 0.85 9.4 4.5 0.39 10.5 0.6 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein NPV_P10 PF05531.12 KDO18496.1 - 1.1 9.8 12.5 2 8.9 2.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 KDO18496.1 - 1.3 9.1 16.2 1.1 9.4 12.7 2.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain PilO PF04350.13 KDO18496.1 - 3.4 7.8 7.8 0.83 9.8 3.3 2.2 2 1 1 3 3 3 0 Pilus assembly protein, PilO DegS PF05384.11 KDO18496.1 - 3.4 7.2 10.3 1.6 8.2 5.1 2.5 2 1 0 2 2 2 0 Sensor protein DegS ADIP PF11559.8 KDO18496.1 - 3.8 7.6 13.2 2.2 8.4 1.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KDO18496.1 - 7.2 6.5 12.7 11 5.9 4.4 2.8 1 1 1 2 2 2 0 Septum formation initiator AAA_25 PF13481.6 KDO18497.1 - 3.7e-23 82.1 0.0 7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 KDO18497.1 - 6.5e-10 39.3 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Toprim-like DnaB_C PF03796.15 KDO18497.1 - 2.5e-08 33.6 0.0 6e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KDO18497.1 - 3.5e-07 30.6 0.2 2.3e-06 28.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 KDO18497.1 - 2.9e-06 26.8 0.0 6.5e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 KDO18497.1 - 2.9e-05 24.5 0.0 7.3e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Toprim_3 PF13362.6 KDO18497.1 - 4.2e-05 23.8 0.0 0.00037 20.8 0.0 2.3 2 0 0 2 2 2 1 Toprim domain ABC_tran PF00005.27 KDO18497.1 - 0.00032 21.2 0.1 0.00064 20.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter Toprim_4 PF13662.6 KDO18497.1 - 0.00081 19.8 0.0 0.0028 18.1 0.0 1.9 2 0 0 2 2 1 1 Toprim domain IstB_IS21 PF01695.17 KDO18497.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KDO18497.1 - 0.0025 17.8 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 KDO18497.1 - 0.0034 17.3 0.2 0.0073 16.2 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.6 KDO18497.1 - 0.0034 17.9 2.0 0.0035 17.9 0.2 1.9 3 0 0 3 3 1 1 AAA domain AAA_28 PF13521.6 KDO18497.1 - 0.0038 17.5 0.5 0.011 15.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO18497.1 - 0.0065 16.9 0.2 0.14 12.6 0.1 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KDO18497.1 - 0.008 16.2 0.1 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KDO18497.1 - 0.0083 15.8 0.2 0.033 13.9 0.2 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 KDO18497.1 - 0.0091 15.6 0.2 0.029 13.9 0.2 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KDO18497.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KDO18497.1 - 0.018 14.5 0.1 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 KDO18497.1 - 0.022 14.7 0.1 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KDO18497.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KDO18497.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Toprim PF01751.22 KDO18497.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 Toprim domain AAA_5 PF07728.14 KDO18497.1 - 0.049 13.6 0.1 0.78 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KDO18497.1 - 0.055 12.6 0.1 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.6 KDO18497.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KDO18497.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase VirE PF05272.11 KDO18497.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_18 PF13238.6 KDO18497.1 - 0.14 12.7 0.2 0.48 11.0 0.1 1.9 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KDO18497.1 - 0.21 11.5 0.2 0.48 10.3 0.2 1.6 1 0 0 1 1 1 0 NTPase Pecanex_C PF05041.15 KDO18500.1 - 3.7e-30 105.2 0.0 6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Vps39_1 PF10366.9 KDO18500.1 - 0.13 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Snf7 PF03357.21 KDO18501.1 - 1.3e-46 158.4 10.4 1.5e-46 158.2 10.4 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KDO18501.1 - 0.0011 19.3 6.5 0.055 13.9 0.7 2.8 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KDO18501.1 - 0.0037 16.9 3.0 0.0048 16.5 3.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF641 PF04859.12 KDO18501.1 - 0.01 16.2 4.6 0.019 15.3 0.1 2.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) XhlA PF10779.9 KDO18501.1 - 0.02 15.1 0.2 0.02 15.1 0.2 2.8 3 1 0 3 3 2 0 Haemolysin XhlA Prefoldin_2 PF01920.20 KDO18501.1 - 0.026 14.5 0.5 0.026 14.5 0.5 3.6 2 1 1 3 3 3 0 Prefoldin subunit HSBP1 PF06825.12 KDO18501.1 - 0.082 12.8 0.1 0.082 12.8 0.1 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 ALMT PF11744.8 KDO18501.1 - 0.083 11.7 0.9 0.089 11.6 0.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RPW8 PF05659.11 KDO18501.1 - 0.086 12.5 5.7 0.065 12.9 3.1 1.8 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.11 KDO18501.1 - 0.1 11.5 9.4 0.14 11.0 9.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KDO18501.1 - 0.15 12.1 4.3 7.8 6.5 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.6 KDO18501.1 - 0.17 12.3 2.4 3.3 8.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) CLZ PF16526.5 KDO18501.1 - 0.17 12.2 0.1 0.17 12.2 0.1 3.2 3 1 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KDO18501.1 - 0.23 11.5 7.0 1.6 8.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 KDO18501.1 - 0.37 10.3 0.1 0.37 10.3 0.1 2.4 3 0 0 3 3 3 0 Intermediate filament protein DUF724 PF05266.14 KDO18501.1 - 0.57 10.0 11.4 1.2 9.0 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FapA PF03961.13 KDO18501.1 - 0.59 8.7 8.4 0.65 8.5 7.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 KDO18501.1 - 0.72 9.1 8.5 3.2 7.0 8.5 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 KDO18501.1 - 0.83 7.5 5.5 1 7.2 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 KDO18501.1 - 0.88 9.7 13.9 5.1 7.3 1.8 2.9 2 1 1 3 3 3 0 Swi5 SNARE PF05739.19 KDO18501.1 - 0.94 9.5 2.4 10 6.2 0.1 2.7 3 0 0 3 3 2 0 SNARE domain DUF2730 PF10805.8 KDO18501.1 - 1.4 9.1 5.1 1.7 8.8 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 KDO18501.1 - 1.5 9.1 20.2 0.14 12.4 2.5 3.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF2890 PF11081.8 KDO18501.1 - 1.6 8.8 7.9 2.2 8.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) MutS_IV PF05190.18 KDO18501.1 - 1.6 9.1 6.4 6.5 7.2 0.9 2.4 1 1 1 2 2 2 0 MutS family domain IV PRKG1_interact PF15898.5 KDO18501.1 - 2.9 8.8 12.2 1.2 10.1 8.1 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 KDO18501.1 - 3.2 8.2 8.4 0.75 10.2 0.1 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) YlqD PF11068.8 KDO18501.1 - 3.4 8.1 11.4 0.58 10.5 4.9 2.2 1 1 1 2 2 2 0 YlqD protein Latarcin PF10279.9 KDO18501.1 - 7.5 7.0 8.7 2.4 8.6 1.7 2.8 2 2 0 2 2 2 0 Latarcin precursor ABC_tran PF00005.27 KDO18502.1 - 1.4e-45 155.2 0.2 3.7e-22 79.3 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KDO18502.1 - 1.1e-23 83.1 9.1 6.1e-22 77.5 8.6 2.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KDO18502.1 - 5.5e-18 65.8 8.7 0.00012 22.0 0.1 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO18502.1 - 4.6e-12 45.9 1.8 0.00058 19.4 0.1 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO18502.1 - 3.4e-08 33.1 0.3 0.0091 15.7 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO18502.1 - 2.1e-06 27.8 0.0 0.036 14.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO18502.1 - 1.7e-05 24.8 0.0 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KDO18502.1 - 2.5e-05 24.6 0.3 0.18 12.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.6 KDO18502.1 - 6.8e-05 22.7 13.1 0.063 13.0 0.1 3.7 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KDO18502.1 - 9.1e-05 23.0 16.2 0.0037 17.8 0.2 4.1 3 2 0 3 3 2 2 AAA domain NACHT PF05729.12 KDO18502.1 - 0.00017 21.6 0.7 0.14 12.0 0.2 2.9 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KDO18502.1 - 0.00037 20.8 0.4 0.14 12.4 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KDO18502.1 - 0.00091 19.0 0.7 2.2 8.0 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 KDO18502.1 - 0.0012 18.6 0.8 1.3 8.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KDO18502.1 - 0.0014 18.0 0.1 2 7.7 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.6 KDO18502.1 - 0.0018 17.9 0.0 1.3 8.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KDO18502.1 - 0.0027 18.1 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF3584 PF12128.8 KDO18502.1 - 0.0034 15.0 0.2 0.0034 15.0 0.2 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) FeoB_N PF02421.18 KDO18502.1 - 0.0038 16.8 1.4 0.16 11.5 0.1 2.7 3 0 0 3 3 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 KDO18502.1 - 0.0042 17.6 0.2 7.4 7.1 0.0 3.3 4 0 0 4 4 2 0 AAA domain Dynamin_N PF00350.23 KDO18502.1 - 0.0047 17.0 8.2 0.62 10.1 0.0 3.7 3 1 1 4 4 3 2 Dynamin family NB-ARC PF00931.22 KDO18502.1 - 0.0048 16.1 0.5 0.27 10.4 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.6 KDO18502.1 - 0.0057 17.1 0.2 0.49 10.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KDO18502.1 - 0.0066 16.6 7.9 0.34 11.0 0.0 4.0 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_33 PF13671.6 KDO18502.1 - 0.013 15.6 3.1 2.2 8.4 0.1 3.2 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KDO18502.1 - 0.015 15.2 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 NTPase Septin PF00735.18 KDO18502.1 - 0.021 14.1 0.0 6.5 5.9 0.0 2.6 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 KDO18502.1 - 0.027 13.6 0.3 3.6 6.6 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit DAP3 PF10236.9 KDO18502.1 - 0.034 13.3 1.9 24 4.0 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 KDO18502.1 - 0.037 14.1 0.4 6.1 6.9 0.0 3.5 3 1 1 4 4 3 0 AAA domain AAA_7 PF12775.7 KDO18502.1 - 0.04 13.4 0.1 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KDO18502.1 - 0.058 13.1 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 KDO18502.1 - 0.059 13.6 0.4 5.5 7.3 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 KDO18502.1 - 0.061 13.3 0.3 9.3 6.3 0.1 2.9 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 KDO18502.1 - 0.061 13.2 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 KDO18502.1 - 0.067 13.2 0.1 12 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Peptidase_M49 PF03571.15 KDO18502.1 - 0.074 11.4 1.0 0.15 10.4 1.0 1.4 1 0 0 1 1 1 0 Peptidase family M49 SRP54 PF00448.22 KDO18502.1 - 0.074 12.7 0.3 2.2 7.9 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.14 KDO18502.1 - 0.086 12.7 0.1 2.1 8.2 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KDO18502.1 - 0.11 12.1 0.7 0.78 9.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 KDO18502.1 - 0.2 11.1 6.1 0.98 8.8 0.1 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein AAA PF00004.29 KDO18502.1 - 0.23 11.9 0.8 5 7.6 0.1 3.1 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NPV_P10 PF05531.12 KDO18502.1 - 0.24 11.9 0.9 0.74 10.3 0.9 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Rop PF01815.16 KDO18502.1 - 0.27 11.1 1.8 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Rop protein DUF16 PF01519.16 KDO18502.1 - 0.43 11.1 7.6 6.7 7.3 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 ATP_bind_1 PF03029.17 KDO18502.1 - 0.9 9.3 3.1 16 5.2 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.6 KDO18502.1 - 0.95 8.0 12.9 2.6 6.6 0.0 4.0 4 1 0 4 4 4 0 AAA domain 7TMR-HDED PF07697.11 KDO18502.1 - 4.6 7.3 6.5 18 5.4 6.5 2.0 1 1 0 1 1 1 0 7TM-HD extracellular Cellulase PF00150.18 KDO18503.1 - 7.1e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KDO18504.1 - 9.7e-22 77.7 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TGF_beta_GS PF08515.12 KDO18504.1 - 0.11 12.0 0.5 0.24 10.9 0.5 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif DUF5305 PF17231.2 KDO18504.1 - 0.17 11.2 0.1 4 6.8 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Thioredoxin_6 PF13848.6 KDO18505.1 - 1.1e-05 25.4 0.0 0.0014 18.6 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 KDO18505.1 - 0.00012 22.0 0.0 0.00081 19.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin PhoR PF11808.8 KDO18506.1 - 3.7 8.0 5.7 0.42 11.0 1.4 1.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Cellulase PF00150.18 KDO18507.1 - 3e-20 72.8 0.0 4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5411 PF17424.2 KDO18507.1 - 0.13 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5411) HlyE PF06109.13 KDO18508.1 - 1e-06 28.3 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Haemolysin E (HlyE) SesA PF17107.5 KDO18508.1 - 0.0036 17.5 0.7 0.13 12.5 0.5 2.6 1 1 2 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Med14 PF08638.11 KDO18508.1 - 0.074 12.5 0.3 0.14 11.5 0.3 1.6 1 1 0 1 1 1 0 Mediator complex subunit MED14 Hemerythrin PF01814.23 KDO18508.1 - 0.12 13.0 0.3 0.35 11.5 0.1 1.9 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Orn_DAP_Arg_deC PF00278.22 KDO18509.1 - 9.8e-20 70.6 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 KDO18509.1 - 3e-05 23.5 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain AhpC-TSA PF00578.21 KDO18510.1 - 1.4e-07 31.5 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO18510.1 - 1.9e-05 24.4 0.1 3.6e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KDO18510.1 - 8.3e-05 22.8 0.2 0.00023 21.4 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO18510.1 - 0.00015 21.7 0.0 0.00048 20.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO18510.1 - 0.00055 20.4 0.1 0.0011 19.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO18510.1 - 0.067 13.4 0.1 0.19 11.9 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like cNMP_binding PF00027.29 KDO18511.1 - 5.9e-18 64.7 1.3 5e-11 42.5 0.1 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Peptidase_M8 PF01457.16 KDO18512.1 - 1.4e-06 27.3 0.0 8.4e-06 24.7 0.0 1.8 1 1 0 1 1 1 1 Leishmanolysin DUF3626 PF12294.8 KDO18512.1 - 0.0084 15.2 0.0 0.01 14.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) COG6 PF06419.11 KDO18513.1 - 1e-80 271.8 0.0 1.2e-80 271.5 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Far-17a_AIG1 PF04750.14 KDO18515.1 - 0.00012 21.5 10.6 0.00012 21.5 10.6 1.6 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein PsbN PF02468.15 KDO18515.1 - 0.03 14.2 0.7 0.16 11.8 0.7 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Far-17a_AIG1 PF04750.14 KDO18516.1 - 0.024 14.0 15.7 0.086 12.1 14.7 2.3 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein Anophelin PF10731.9 KDO18516.1 - 0.85 9.5 2.3 24 4.8 0.3 2.9 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito Far-17a_AIG1 PF04750.14 KDO18517.1 - 9.4e-07 28.3 14.9 4.6e-06 26.1 14.8 2.1 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Cation_ATPase_C PF00689.21 KDO18518.1 - 0.44 10.2 5.2 1.1 8.9 5.2 2.0 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus UEV PF05743.13 KDO18519.1 - 0.1 12.4 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 UEV domain HOOK PF05622.12 KDO18521.1 - 0.00076 17.8 6.7 0.00097 17.4 6.7 1.0 1 0 0 1 1 1 1 HOOK protein DUF4407 PF14362.6 KDO18521.1 - 0.0032 16.9 5.8 0.0037 16.6 5.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SOGA PF11365.8 KDO18521.1 - 0.0045 18.1 3.4 4.8 8.4 0.0 2.8 2 1 0 2 2 2 1 Protein SOGA Tmemb_cc2 PF10267.9 KDO18521.1 - 0.0063 15.7 3.2 0.011 14.9 3.2 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Mod_r PF07200.13 KDO18521.1 - 0.0087 16.2 7.9 0.0087 16.2 7.9 1.8 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 KDO18521.1 - 0.0099 16.0 0.8 0.15 12.2 0.8 2.7 1 1 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.8 KDO18521.1 - 0.011 15.9 2.6 0.011 15.9 2.6 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3452 PF11934.8 KDO18521.1 - 0.013 15.0 0.1 0.026 14.1 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) MPS2 PF17060.5 KDO18521.1 - 0.022 14.0 2.4 0.026 13.8 2.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 GIT_CC PF16559.5 KDO18521.1 - 0.033 14.1 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nnf1 PF03980.14 KDO18521.1 - 0.06 13.7 6.6 0.23 11.9 0.1 2.5 2 0 0 2 2 2 0 Nnf1 CEP63 PF17045.5 KDO18521.1 - 0.07 13.0 9.2 1.6 8.5 4.7 2.2 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa FH2 PF02181.23 KDO18521.1 - 0.077 12.1 4.7 0.042 13.0 1.3 1.8 2 0 0 2 2 2 0 Formin Homology 2 Domain YabA PF06156.13 KDO18521.1 - 0.081 13.6 4.8 0.28 11.8 4.8 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 KDO18521.1 - 0.11 12.6 8.1 0.62 10.2 1.7 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KDO18521.1 - 0.19 10.6 9.5 0.46 9.3 0.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein STAT_alpha PF01017.20 KDO18521.1 - 0.26 11.2 7.2 0.12 12.3 3.9 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain BCDHK_Adom3 PF10436.9 KDO18521.1 - 0.28 11.0 2.4 0.77 9.6 1.8 1.8 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase KASH_CCD PF14662.6 KDO18521.1 - 0.29 10.9 8.4 0.86 9.4 3.4 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Syntaxin-6_N PF09177.11 KDO18521.1 - 0.38 11.3 7.1 0.66 10.6 1.4 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KfrA_N PF11740.8 KDO18521.1 - 0.47 11.1 10.1 0.93 10.2 4.5 2.6 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Herpes_BLRF2 PF05812.12 KDO18521.1 - 0.71 10.0 5.8 0.52 10.5 1.8 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein HalX PF08663.10 KDO18521.1 - 1.2 9.6 8.7 1.7 9.0 1.5 2.7 1 1 1 2 2 2 0 HalX domain APG6_N PF17675.1 KDO18521.1 - 1.5 9.3 14.8 0.081 13.5 5.5 2.2 1 1 0 2 2 2 0 Apg6 coiled-coil region KLRAQ PF10205.9 KDO18521.1 - 1.9 8.8 8.5 0.97 9.7 4.3 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein BST2 PF16716.5 KDO18521.1 - 4.8 7.8 11.9 6.1 7.5 0.3 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 HR1 PF02185.16 KDO18521.1 - 5 7.3 10.1 8.9 6.5 6.5 2.8 2 1 0 2 2 1 0 Hr1 repeat UPF0242 PF06785.11 KDO18521.1 - 5.1 7.2 10.8 62 3.6 10.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KDO18521.1 - 6.1 6.1 9.0 20 4.4 9.0 1.9 1 1 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 KDO18521.1 - 9.3 6.7 9.0 6.8 7.1 0.1 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Ferritin_2 PF13668.6 KDO18522.1 - 0.009 16.2 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain SDF PF00375.18 KDO18523.1 - 2.4e-97 326.4 33.5 2.7e-97 326.3 33.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FYVE PF01363.21 KDO18524.1 - 2.7e-05 24.2 6.2 4.9e-05 23.4 6.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 KDO18524.1 - 0.012 15.3 2.2 0.023 14.4 2.2 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Pkinase PF00069.25 KDO18525.1 - 8.2e-52 176.2 0.0 1.1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18525.1 - 2.5e-47 161.4 0.0 3.1e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 KDO18525.1 - 0.00076 18.8 3.0 0.00076 18.8 3.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 KDO18525.1 - 0.002 17.0 0.1 0.003 16.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Adeno_E3_CR2 PF02439.15 KDO18525.1 - 0.0023 17.6 0.7 0.0043 16.8 0.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Kinase-like PF14531.6 KDO18525.1 - 0.0066 15.8 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like EphA2_TM PF14575.6 KDO18525.1 - 0.032 15.1 0.1 0.059 14.3 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 KDO18525.1 - 0.033 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syndecan PF01034.20 KDO18525.1 - 0.041 13.8 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain SRTM1 PF15872.5 KDO18525.1 - 0.086 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Protocadherin PF08374.11 KDO18525.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Protocadherin Haspin_kinase PF12330.8 KDO18525.1 - 0.11 11.4 0.0 0.66 8.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KDO18525.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3357 PF11837.8 KDO18525.1 - 0.16 12.4 1.5 19 5.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Pkinase PF00069.25 KDO18526.1 - 3.3e-51 174.2 0.0 4.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18526.1 - 1.3e-47 162.3 0.0 1.8e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase T4SS_CagC PF16943.5 KDO18526.1 - 0.003 17.7 0.2 0.028 14.6 0.2 2.3 2 0 0 2 2 2 1 Cag pathogenicity island, type IV secretory system Pkinase_fungal PF17667.1 KDO18526.1 - 0.0044 15.8 0.1 0.0067 15.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO18526.1 - 0.0089 15.4 0.0 0.037 13.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO18526.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBR PF01485.21 KDO18529.1 - 1.5e-11 44.4 16.6 6.9e-09 35.8 3.3 2.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-UDP PF14569.6 KDO18529.1 - 0.15 12.2 8.7 1 9.6 0.8 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger C1_4 PF07975.12 KDO18529.1 - 0.16 12.2 6.8 0.24 11.7 3.0 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain LCAT PF02450.15 KDO18531.1 - 8e-57 193.2 0.0 1.3e-56 192.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Acyl_transf_1 PF00698.21 KDO18531.1 - 3.1e-37 128.8 0.9 4.8e-37 128.2 0.9 1.2 1 0 0 1 1 1 1 Acyl transferase domain DUF676 PF05057.14 KDO18531.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KDO18531.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ank_2 PF12796.7 KDO18532.1 - 1.1e-25 90.1 28.4 5.8e-09 36.4 1.8 6.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18532.1 - 2.3e-20 72.7 15.8 2.6e-06 27.9 0.2 8.2 4 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18532.1 - 5.6e-18 64.8 26.8 0.015 15.6 0.2 11.1 3 2 8 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18532.1 - 2.6e-12 45.7 14.1 0.37 11.5 0.1 10.0 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 KDO18532.1 - 1.7e-06 28.2 26.5 0.66 10.5 1.3 8.2 5 4 2 7 7 7 4 Ankyrin repeat Ribonuclease_T2 PF00445.18 KDO18533.1 - 0.00026 21.3 0.0 0.00043 20.6 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease T2 family Esterase PF00756.20 KDO18535.1 - 1.8e-36 126.1 0.3 2e-36 125.9 0.3 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KDO18535.1 - 3.6e-05 23.4 0.3 0.00038 20.0 0.2 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO18535.1 - 0.00057 19.2 0.2 0.00087 18.6 0.1 1.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KDO18535.1 - 0.0007 18.6 0.0 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KDO18535.1 - 0.0036 17.0 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KDO18535.1 - 0.011 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 KDO18535.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 KDO18535.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF1190 PF06693.11 KDO18537.1 - 0.011 16.1 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) EMP70 PF02990.16 KDO18538.1 - 4.3e-159 530.5 5.4 6.2e-159 530.0 5.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 KDO18538.1 - 0.0025 16.8 13.6 0.0025 16.8 13.6 3.1 1 1 2 3 3 3 1 Major Facilitator Superfamily TatD_DNase PF01026.21 KDO18539.1 - 6.4e-25 88.0 0.0 1.1e-21 77.4 0.0 2.1 1 1 1 2 2 2 2 TatD related DNase UL41A PF17591.2 KDO18539.1 - 0.11 12.7 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL41A ubiquitin PF00240.23 KDO18541.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin family ubiquitin PF00240.23 KDO18542.1 - 1.3e-18 66.5 0.1 9.9e-18 63.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KDO18542.1 - 1.9e-10 40.4 0.4 4.2e-09 36.1 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_2 PF13639.6 KDO18542.1 - 4.7e-05 23.6 3.1 0.0001 22.6 3.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO18542.1 - 0.77 9.6 3.8 2.7 7.9 3.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO18542.1 - 1.2 9.5 4.6 5.3 7.4 4.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain DnaJ PF00226.31 KDO18543.1 - 1.2e-21 76.6 0.1 1.2e-21 76.6 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 KDO18543.1 - 7.9e-10 38.8 7.3 1.1e-08 35.1 4.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO18543.1 - 6.7e-08 32.7 2.9 6.7e-08 32.7 2.9 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KDO18543.1 - 1.3e-06 28.6 3.6 0.00053 20.3 0.5 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KDO18543.1 - 4.5e-06 27.0 12.9 0.0049 17.1 0.3 3.1 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 KDO18543.1 - 1.6e-05 25.1 5.0 0.041 14.3 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO18543.1 - 1.8e-05 25.2 3.2 0.027 15.3 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KDO18543.1 - 0.003 17.5 6.7 0.095 12.7 2.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-DBF PF07535.12 KDO18543.1 - 0.021 14.9 2.3 0.058 13.5 0.2 2.6 2 0 0 2 2 2 0 DBF zinc finger Lipase_3 PF01764.25 KDO18545.1 - 1.1e-08 35.1 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO18545.1 - 0.0012 19.5 3.2 0.0012 19.5 3.2 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family CAT PF00302.18 KDO18545.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase Esterase PF00756.20 KDO18545.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase ABC1 PF03109.16 KDO18546.1 - 2.4e-20 72.9 0.0 4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KDO18546.1 - 9.2e-08 31.8 0.0 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KDO18546.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO18546.1 - 0.016 15.1 0.1 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PhosphMutase PF10143.9 KDO18547.1 - 0.00015 21.7 0.2 0.0002 21.3 0.2 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 KDO18547.1 - 0.017 14.5 0.0 0.018 14.4 0.0 1.0 1 0 0 1 1 1 0 Metalloenzyme superfamily Pkinase PF00069.25 KDO18548.1 - 7.2e-32 110.8 0.0 9.1e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18548.1 - 1.3e-31 109.8 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18548.1 - 0.00025 20.5 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SKN1 PF03935.15 KDO18549.1 - 5.7e-61 206.5 19.4 5.7e-25 87.7 0.3 5.4 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO18549.1 - 0.063 13.6 4.2 0.065 13.5 1.7 2.3 2 0 0 2 2 2 0 EB module Ank_2 PF12796.7 KDO18550.1 - 3.8e-39 133.2 9.4 8.2e-12 45.6 0.1 6.7 4 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18550.1 - 1.8e-32 111.3 5.6 1.6e-09 38.1 0.1 8.9 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO18550.1 - 3.3e-31 108.6 0.0 5.7e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18550.1 - 1e-24 87.2 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KDO18550.1 - 3e-24 84.7 7.9 0.00012 22.3 0.2 7.2 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18550.1 - 3.6e-20 69.9 9.2 0.0037 17.7 0.0 10.9 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 KDO18550.1 - 9.7e-18 63.8 17.6 0.016 15.6 0.0 9.8 10 0 0 10 10 10 5 Ankyrin repeat Kdo PF06293.14 KDO18550.1 - 0.098 12.0 0.2 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TraH_2 PF06871.11 KDO18550.1 - 0.13 11.9 0.4 0.3 10.7 0.2 1.7 2 0 0 2 2 2 0 TraH_2 CBM_1 PF00734.18 KDO18551.1 - 2.6e-17 62.5 27.2 1.2e-09 38.0 6.2 4.2 6 0 0 6 6 6 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO18551.1 - 0.014 15.7 9.0 0.068 13.4 0.5 3.3 3 0 0 3 3 3 0 Toxin 7 PAN_4 PF14295.6 KDO18551.1 - 0.044 13.7 0.8 0.044 13.7 0.8 3.9 3 1 0 4 4 4 0 PAN domain CBM_1 PF00734.18 KDO18552.1 - 1.2e-17 63.6 29.3 7.7e-10 38.6 13.3 4.3 7 0 0 7 7 7 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO18552.1 - 0.0059 16.8 8.6 0.33 11.2 0.3 3.1 3 0 0 3 3 3 2 Toxin 7 VP4_2 PF08935.10 KDO18552.1 - 0.025 15.1 0.6 0.066 13.8 0.6 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit CBM_1 PF00734.18 KDO18553.1 - 5.1e-17 61.5 30.8 3.5e-10 39.7 12.9 3.6 4 0 0 4 4 4 2 Fungal cellulose binding domain DUF4454 PF14628.6 KDO18553.1 - 0.034 14.0 0.5 0.063 13.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Glycolytic PF00274.19 KDO18553.1 - 0.083 11.6 0.3 0.12 11.1 0.3 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Toxin_7 PF05980.12 KDO18553.1 - 0.35 11.2 10.6 0.83 10.0 0.7 3.0 3 0 0 3 3 3 0 Toxin 7 CBM_1 PF00734.18 KDO18554.1 - 4.5e-18 64.9 22.1 4.4e-10 39.3 6.2 4.2 6 0 0 6 6 6 2 Fungal cellulose binding domain RE_HindIII PF09518.10 KDO18554.1 - 0.071 12.3 0.5 0.1 11.8 0.5 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease CBM_1 PF00734.18 KDO18555.1 - 1.6e-16 59.9 26.4 2.5e-10 40.1 7.7 3.5 3 1 0 3 3 3 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO18555.1 - 0.081 13.2 7.2 1.1 9.6 2.5 3.0 2 0 0 2 2 2 0 Toxin 7 Dickkopf_N PF04706.12 KDO18555.1 - 7.3 7.2 12.7 0.76 10.3 0.4 3.2 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region ADK PF00406.22 KDO18556.1 - 1.7e-45 154.8 0.0 2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KDO18556.1 - 9.1e-25 87.7 0.0 1.6e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO18556.1 - 4.8e-07 30.4 0.0 8.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO18556.1 - 0.0017 18.6 0.0 0.0052 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KDO18556.1 - 0.0054 16.7 0.2 0.036 14.0 0.0 2.4 2 1 0 2 2 2 1 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 KDO18556.1 - 0.0074 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Limkain-b1 PF11608.8 KDO18556.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Thymidylate_kin PF02223.17 KDO18556.1 - 0.013 15.2 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Hydin_ADK PF17213.3 KDO18556.1 - 0.042 14.1 0.2 10 6.4 0.1 2.2 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Ala_racemase_N PF01168.20 KDO18557.1 - 0.071 12.8 1.0 0.43 10.2 0.0 2.5 2 1 0 2 2 2 0 Alanine racemase, N-terminal domain LRR_6 PF13516.6 KDO18557.1 - 0.16 12.1 5.5 0.27 11.4 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat SDF PF00375.18 KDO18560.1 - 1.2e-62 212.2 36.2 3.7e-60 204.0 36.2 2.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SAT PF16073.5 KDO18562.1 - 0.00023 21.0 0.2 0.00049 19.9 0.2 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Nif11 PF07862.11 KDO18562.1 - 0.02 15.2 0.9 0.15 12.4 0.0 2.8 3 0 0 3 3 3 0 Nif11 domain Prefoldin PF02996.17 KDO18565.1 - 2.6e-27 95.1 0.1 3.2e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Cauli_AT PF03233.13 KDO18565.1 - 0.032 14.2 0.2 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Aphid transmission protein Prefoldin_2 PF01920.20 KDO18565.1 - 0.054 13.5 0.0 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 KDO18565.1 - 0.057 13.0 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TPR_2 PF07719.17 KDO18568.1 - 1.4e-28 96.7 8.3 0.0022 18.0 0.0 9.4 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KDO18568.1 - 2.4e-28 96.8 6.3 9.6e-06 25.2 0.0 8.8 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KDO18568.1 - 1.7e-20 73.1 4.9 0.00086 19.5 0.0 6.7 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KDO18568.1 - 4e-20 70.3 2.1 0.031 14.5 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KDO18568.1 - 1e-17 64.4 5.2 0.00091 19.7 0.0 6.8 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO18568.1 - 1.3e-17 64.2 4.9 0.021 15.4 0.0 6.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KDO18568.1 - 4.6e-16 58.1 6.8 0.00047 20.8 0.0 8.9 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO18568.1 - 1e-13 50.6 8.4 0.0067 16.7 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO18568.1 - 2.9e-10 39.4 7.9 0.18 11.9 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO18568.1 - 1.7e-09 37.7 3.5 0.8 10.5 0.1 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO18568.1 - 6e-09 35.9 4.0 0.018 15.2 0.1 4.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO18568.1 - 8.7e-08 31.7 13.0 0.098 12.4 0.0 7.1 6 2 2 8 8 8 2 TPR repeat TPR_15 PF13429.6 KDO18568.1 - 4e-05 23.0 3.8 0.0077 15.5 0.0 4.4 2 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO18568.1 - 0.0014 18.8 14.9 0.9 9.8 0.1 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KDO18568.1 - 0.015 15.3 1.3 1.3 9.1 0.1 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KDO18568.1 - 0.017 15.0 8.0 0.57 10.1 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KDO18568.1 - 0.05 13.3 0.4 1.5 8.5 0.1 2.7 2 2 0 2 2 2 0 26S proteasome subunit RPN7 Sel1 PF08238.12 KDO18569.1 - 9.1e-32 108.8 22.3 3.9e-06 27.4 0.1 8.7 8 1 1 9 9 9 7 Sel1 repeat TPR_6 PF13174.6 KDO18569.1 - 0.005 17.4 13.9 0.029 15.0 0.3 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KDO18570.1 - 0.00028 21.5 0.0 0.00051 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18570.1 - 0.00031 21.4 0.0 0.00055 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO18570.1 - 0.00079 19.3 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO18570.1 - 0.001 19.7 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO18570.1 - 0.095 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 KDO18577.1 - 2.6e-37 126.4 34.3 4.9e-07 30.2 0.4 8.2 9 0 0 9 9 9 6 Sel1 repeat TPR_6 PF13174.6 KDO18577.1 - 0.0023 18.4 21.3 1.1 10.1 0.2 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO18577.1 - 0.24 11.6 0.1 0.24 11.6 0.1 8.8 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO18577.1 - 0.54 11.2 0.0 0.54 11.2 0.0 6.0 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO18577.1 - 0.71 9.8 0.0 0.71 9.8 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO18577.1 - 1.4 9.3 0.0 1.4 9.3 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO18577.1 - 4 7.7 14.3 9.5 6.5 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO18578.1 - 2.6e-61 207.3 0.0 3.3e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18578.1 - 7.2e-28 97.6 0.0 9.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18578.1 - 4.5e-09 36.1 0.0 6.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 KDO18578.1 - 7.7e-05 23.2 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KDO18578.1 - 0.0002 20.3 0.2 0.00033 19.6 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO18578.1 - 0.019 14.4 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO18578.1 - 0.02 13.9 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KDO18578.1 - 0.023 13.6 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO18578.1 - 0.048 13.6 0.9 0.31 10.9 0.8 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KDO18578.1 - 0.3 11.8 4.6 0.67 10.7 4.6 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain FtsJ PF01728.19 KDO18579.1 - 5.3e-31 108.1 0.0 9.5e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Globin PF00042.22 KDO18580.1 - 0.00033 21.2 0.1 0.00077 20.0 0.1 1.6 1 1 0 1 1 1 1 Globin TusA PF01206.17 KDO18580.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA CFC PF09443.10 KDO18581.1 - 0.019 14.8 1.3 0.044 13.6 1.3 1.6 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Wax2_C PF12076.8 KDO18581.1 - 0.095 12.4 2.0 0.18 11.5 2.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain AIF-MLS PF14962.6 KDO18582.1 - 0.031 14.2 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence EF-hand_7 PF13499.6 KDO18583.1 - 4.1e-17 62.4 2.4 1.6e-12 47.7 0.4 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO18583.1 - 4.2e-15 54.1 5.1 9.2e-07 28.0 0.2 4.3 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KDO18583.1 - 1.8e-13 50.1 2.1 6.4e-09 35.5 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO18583.1 - 3.2e-13 48.5 5.3 5.1e-07 29.1 0.1 4.1 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KDO18583.1 - 1e-06 27.9 2.4 0.00066 19.1 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 KDO18583.1 - 0.11 12.4 0.2 0.5 10.3 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand PRP4 PF08799.11 KDO18583.1 - 7.7 6.2 6.8 4.4 6.9 0.0 3.1 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like Fer2 PF00111.27 KDO18584.1 - 8.5e-07 28.8 0.5 1.2e-06 28.4 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_2 PF01799.20 KDO18584.1 - 0.00028 20.9 0.3 0.00028 20.9 0.3 1.8 2 0 0 2 2 2 1 [2Fe-2S] binding domain DHODB_Fe-S_bind PF10418.9 KDO18584.1 - 0.011 15.6 1.1 0.011 15.6 1.1 1.8 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2_3 PF13085.6 KDO18584.1 - 0.13 12.2 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain MORN PF02493.20 KDO18585.1 - 1.5e-28 96.9 40.6 6.9e-06 25.6 1.8 8.4 8 0 0 8 8 8 8 MORN repeat IKI3 PF04762.12 KDO18588.1 - 1.2e-149 500.2 1.2 8.5e-80 269.0 0.0 3.1 1 1 1 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 KDO18588.1 - 0.0011 19.2 5.2 0.026 14.8 0.3 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Tim17 PF02466.19 KDO18589.1 - 9.6e-20 71.0 7.8 1.2e-19 70.7 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KDO18589.1 - 0.0025 18.1 7.4 0.16 12.4 3.7 2.8 2 1 1 3 3 3 2 Reactive mitochondrial oxygen species modulator 1 HSA PF07529.13 KDO18591.1 - 5e-12 46.0 5.0 2e-11 44.0 4.9 2.1 1 1 0 1 1 1 1 HSA Myb_DNA-binding PF00249.31 KDO18591.1 - 1.4e-05 25.2 1.3 0.00014 22.0 0.3 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO18591.1 - 0.0002 21.5 1.6 0.0004 20.6 0.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain SNF2_N PF00176.23 KDO18591.1 - 0.0018 17.1 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DUF2457 PF10446.9 KDO18591.1 - 1.7 7.7 12.5 3.5 6.7 12.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TPH PF13868.6 KDO18592.1 - 6.1e-11 41.4 14.0 6.1e-11 41.4 14.0 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain EFhand_Ca_insen PF08726.10 KDO18592.1 - 0.022 14.8 0.2 0.059 13.5 0.2 1.8 1 0 0 1 1 1 0 Ca2+ insensitive EF hand HATPase_c_4 PF13749.6 KDO18592.1 - 0.079 13.1 0.8 0.21 11.7 0.8 1.8 1 0 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal DUF2175 PF09943.9 KDO18592.1 - 9.6 6.6 8.5 3.1 8.2 4.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) IQ PF00612.27 KDO18593.1 - 0.0068 16.1 2.6 0.03 14.1 2.6 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dynein_light PF01221.18 KDO18594.1 - 2.5e-25 88.6 0.3 2.9e-25 88.4 0.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 COOH-NH2_lig PF14395.6 KDO18594.1 - 0.0043 16.3 0.0 0.0048 16.2 0.0 1.1 1 0 0 1 1 1 1 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF4854 PF16146.5 KDO18594.1 - 0.018 15.4 0.1 0.022 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) ApoO PF09769.9 KDO18594.1 - 0.061 13.3 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O ACBP PF00887.19 KDO18595.1 - 7e-11 42.2 0.0 2e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein US22 PF02393.16 KDO18595.1 - 0.0021 18.4 4.1 0.084 13.1 0.0 4.0 4 1 0 4 4 4 1 US22 like Herpes_UL3 PF03369.13 KDO18595.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL3 protein Peptidase_C1 PF00112.23 KDO18597.1 - 2e-60 204.6 13.3 2.2e-60 204.4 12.4 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO18597.1 - 4.9e-06 25.6 2.3 0.0031 16.4 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KDO18597.1 - 0.093 13.2 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) BT1 PF03092.16 KDO18598.1 - 4.2e-14 51.7 10.2 2.8e-13 48.9 1.8 2.4 2 0 0 2 2 2 2 BT1 family BT1 PF03092.16 KDO18602.1 - 1.1e-17 63.5 12.3 3.3e-15 55.3 2.2 2.4 2 0 0 2 2 2 2 BT1 family OrsD PF12013.8 KDO18603.1 - 0.18 12.2 2.3 0.56 10.7 0.1 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 KDO18604.1 - 1.6e-13 50.9 0.0 3.9e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KDO18604.1 - 7e-08 32.7 0.0 2.9e-07 30.8 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KDO18604.1 - 5.7e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KDO18604.1 - 1.2e-05 25.5 6.1 1.2e-05 25.5 6.1 3.9 3 0 0 3 3 2 1 Ring finger domain IBR PF01485.21 KDO18604.1 - 5.5e-05 23.3 3.5 5.5e-05 23.3 3.5 4.5 4 0 0 4 4 4 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KDO18604.1 - 0.00022 21.0 5.8 0.00022 21.0 5.8 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO18604.1 - 0.00049 20.1 9.2 0.00049 20.1 9.2 3.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO18604.1 - 0.0014 18.5 7.8 0.0014 18.5 7.8 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) AAA_30 PF13604.6 KDO18604.1 - 0.0022 17.8 0.1 0.0053 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KDO18604.1 - 0.0031 17.3 0.0 0.0084 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO18604.1 - 0.0038 17.5 0.0 0.015 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO18604.1 - 0.0063 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KDO18604.1 - 0.019 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain GerPB PF10803.8 KDO18604.1 - 0.026 14.6 0.2 7.8 6.7 0.1 2.4 2 0 0 2 2 2 0 Spore germination GerPB AAA_16 PF13191.6 KDO18604.1 - 0.08 13.3 0.1 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain BUD22 PF09073.10 KDO18604.1 - 0.89 8.8 7.2 1.9 7.7 0.7 2.1 2 0 0 2 2 2 0 BUD22 DLIC PF05783.11 KDO18605.1 - 2.1e-07 30.2 0.0 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 KDO18605.1 - 0.00082 19.6 0.0 0.0027 17.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TIG PF01833.24 KDO18606.1 - 0.064 13.3 1.2 3.8 7.6 0.1 2.4 2 0 0 2 2 2 0 IPT/TIG domain PQQ_3 PF13570.6 KDO18606.1 - 6.2 7.4 18.3 29 5.3 0.2 5.4 4 1 0 4 4 4 0 PQQ-like domain Ank_2 PF12796.7 KDO18607.1 - 5.4e-110 360.2 25.1 1.3e-19 70.5 0.3 8.8 2 1 9 11 11 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18607.1 - 3e-80 263.7 15.7 2.3e-11 44.0 0.1 13.6 4 4 10 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.30 KDO18607.1 - 7e-80 260.3 42.6 2e-07 31.1 0.6 15.9 17 0 0 17 17 16 13 Ankyrin repeat Ank_3 PF13606.6 KDO18607.1 - 1.1e-71 228.1 19.1 8.7e-05 22.7 0.0 16.7 17 0 0 17 17 17 15 Ankyrin repeat Ank_5 PF13857.6 KDO18607.1 - 8.8e-68 223.5 28.0 7.3e-10 38.9 0.2 12.5 4 2 9 13 13 13 13 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO18607.1 - 1.1e-43 149.4 0.0 1.5e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18607.1 - 4.5e-43 147.5 0.0 6.5e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO18607.1 - 0.0014 17.6 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO18607.1 - 0.0071 15.2 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sbt_1 PF05982.12 KDO18607.1 - 0.035 13.4 0.3 2.2 7.4 0.1 2.8 3 0 0 3 3 3 0 Na+-dependent bicarbonate transporter superfamily GATase_7 PF13537.6 KDO18607.1 - 0.12 12.3 0.0 74 3.3 0.0 3.9 3 0 0 3 3 3 0 Glutamine amidotransferase domain PEGA PF08308.11 KDO18607.1 - 0.12 12.2 0.0 48 4.0 0.0 4.5 5 0 0 5 5 5 0 PEGA domain Methyltr_RsmB-F PF01189.17 KDO18612.1 - 3.6e-13 49.6 0.0 5.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F SMC_N PF02463.19 KDO18613.1 - 4e-32 111.4 0.0 1.1e-31 110.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO18613.1 - 2e-19 70.9 0.2 2e-19 70.9 0.2 5.8 2 2 2 5 5 5 1 AAA domain AAA_15 PF13175.6 KDO18613.1 - 5.8e-12 46.0 8.4 5.8e-12 46.0 8.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KDO18613.1 - 3.4e-09 36.9 0.3 0.00018 21.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO18613.1 - 0.00011 21.8 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.19 KDO18613.1 - 0.00052 19.9 29.2 0.00052 19.9 29.2 3.7 2 1 1 3 3 3 1 Ezrin/radixin/moesin family SbcCD_C PF13558.6 KDO18613.1 - 0.014 15.6 0.1 0.059 13.6 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UvrA_DNA-bind PF17755.1 KDO18613.1 - 0.022 15.1 0.2 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 UvrA DNA-binding domain CCDC144C PF14915.6 KDO18614.1 - 0.037 13.1 3.3 0.97 8.5 0.2 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Fez1 PF06818.15 KDO18614.1 - 0.11 12.9 0.9 0.16 12.4 0.9 1.2 1 0 0 1 1 1 0 Fez1 YscO PF07321.12 KDO18614.1 - 0.48 10.4 6.4 0.92 9.5 6.3 1.4 1 1 0 1 1 1 0 Type III secretion protein YscO ECH_1 PF00378.20 KDO18615.1 - 7.1e-15 55.0 0.1 7.6e-15 54.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO18615.1 - 0.0011 18.6 0.5 0.11 12.0 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase TRAM_LAG1_CLN8 PF03798.16 KDO18616.1 - 1.9e-19 70.2 15.4 2.7e-19 69.7 15.4 1.2 1 0 0 1 1 1 1 TLC domain PIG-Y PF15159.6 KDO18620.1 - 1.3e-20 74.0 1.6 1.7e-20 73.7 1.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LRR_4 PF12799.7 KDO18621.1 - 0.19 12.2 0.1 0.9 10.1 0.0 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO18621.1 - 0.44 10.3 2.5 0.79 9.5 1.2 2.2 2 1 0 2 2 2 0 Leucine rich repeat Pkinase PF00069.25 KDO18622.1 - 1.6e-44 152.2 0.0 2.1e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18622.1 - 1.1e-43 149.4 0.0 1.3e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO18622.1 - 7.1e-06 26.1 0.1 0.0098 15.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO18622.1 - 0.0032 16.3 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO18622.1 - 0.028 13.4 0.0 0.066 12.2 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Cupin_5 PF06172.11 KDO18623.1 - 9.6e-28 97.1 0.0 1.2e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) zf-C4H2 PF10146.9 KDO18624.1 - 0.0028 18.0 2.8 0.0059 16.9 2.8 1.5 1 0 0 1 1 1 1 Zinc finger-containing protein Elicitin PF00964.17 KDO18625.1 - 3.5e-06 27.0 0.1 4.9e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO18626.1 - 6.2e-08 32.6 0.1 8.5e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO18627.1 - 1.6e-05 24.9 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO18628.1 - 8.8e-05 22.5 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Elicitin DUF4381 PF14316.6 KDO18628.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Elicitin PF00964.17 KDO18629.1 - 0.022 14.8 0.3 0.044 13.9 0.3 1.5 1 1 0 1 1 1 0 Elicitin TGF_beta_GS PF08515.12 KDO18631.1 - 0.037 13.5 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif UL73_N PF12522.8 KDO18631.1 - 2.9 7.7 5.3 6 6.7 5.3 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal CxC6 PF18721.1 KDO18634.1 - 2 8.7 30.4 1.4 9.2 1.5 4.1 1 1 3 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases MULE PF10551.9 KDO18638.1 - 5e-06 26.8 0.1 2.9e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 KDO18638.1 - 0.0055 16.4 0.2 0.0055 16.4 0.2 2.0 2 0 0 2 2 2 1 SWIM zinc finger Spem1 PF15670.5 KDO18644.1 - 0.091 12.3 0.2 0.1 12.2 0.2 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 Filamin PF00630.19 KDO18647.1 - 5.7e-41 139.5 0.0 1.4e-08 35.4 0.0 7.9 8 0 0 8 8 8 6 Filamin/ABP280 repeat Invasin_D3 PF09134.10 KDO18647.1 - 2.2e-12 47.1 38.8 0.0034 17.7 0.6 8.9 8 0 0 8 8 8 5 Invasin, domain 3 PA14 PF07691.12 KDO18647.1 - 8.6e-08 32.1 0.3 2.1e-06 27.6 0.0 3.0 3 0 0 3 3 3 1 PA14 domain EGF_2 PF07974.13 KDO18647.1 - 6.9e-06 26.3 27.9 0.0012 19.2 10.3 3.0 2 0 0 2 2 2 2 EGF-like domain Calx-beta PF03160.14 KDO18647.1 - 2.1e-05 24.6 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Calx-beta domain GLEYA PF10528.9 KDO18647.1 - 0.031 14.7 0.4 0.55 10.7 0.1 3.4 2 1 0 2 2 2 0 GLEYA domain Cadherin_5 PF17892.1 KDO18647.1 - 0.12 12.4 3.9 2 8.5 0.1 3.4 3 0 0 3 3 3 0 Cadherin-like domain zf-TAZ PF02135.16 KDO18648.1 - 9.8e-23 80.4 47.5 4.3e-13 49.5 19.9 3.4 3 0 0 3 3 3 2 TAZ zinc finger LPD11 PF18824.1 KDO18648.1 - 0.01 15.9 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 zf_CCCH_4 PF18345.1 KDO18648.1 - 0.033 14.3 0.3 0.1 12.7 0.3 1.9 1 0 0 1 1 1 0 Zinc finger domain zf-C2HC PF01530.18 KDO18648.1 - 0.47 10.7 4.7 5.5 7.3 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2HC type DUF4045 PF13254.6 KDO18648.1 - 3.3 7.3 26.8 0.73 9.4 20.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Hid1 PF12722.7 KDO18648.1 - 5.4 5.0 21.8 8.7 4.3 21.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 KDO18648.1 - 6.4 5.5 19.9 9.7 4.9 19.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 KDO18648.1 - 8.8 4.7 30.0 8.2 4.8 29.2 1.4 1 1 0 1 1 1 0 Macoilin family tRNA-synt_2b PF00587.25 KDO18649.1 - 7.7e-40 136.8 0.0 1.4e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KDO18649.1 - 5.9e-20 71.2 0.2 1.1e-19 70.4 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KDO18649.1 - 4.5e-09 36.3 0.1 2.6e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain NHL PF01436.21 KDO18650.1 - 2e-21 74.9 2.7 2.5e-07 30.4 0.7 6.4 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 KDO18650.1 - 0.03 13.9 5.4 0.18 11.3 0.5 3.5 2 2 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 KDO18650.1 - 0.63 10.1 6.6 7.2 6.7 0.3 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Kelch_5 PF13854.6 KDO18651.1 - 1.9e-41 139.5 6.5 9.7e-07 28.7 0.0 6.5 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KDO18651.1 - 1.5e-31 108.0 17.2 5.7e-08 32.9 0.1 8.1 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO18651.1 - 8.5e-31 105.2 8.9 5.6e-05 23.3 0.0 7.2 5 2 2 7 7 7 6 Kelch motif Kelch_4 PF13418.6 KDO18651.1 - 6.5e-30 102.9 12.9 1.2e-07 31.7 0.1 6.2 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KDO18651.1 - 3.1e-29 99.8 16.8 0.00028 20.8 0.2 7.2 6 2 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KDO18651.1 - 1.6e-28 98.0 8.1 5.5e-05 22.7 0.1 6.6 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 KDO18651.1 - 0.0036 17.7 8.9 1.4 9.5 0.1 5.5 5 0 0 5 5 5 1 PQQ-like domain RAG2 PF03089.14 KDO18651.1 - 0.064 12.2 1.8 0.5 9.3 0.0 3.1 4 1 1 5 5 5 0 Recombination activating protein 2 Cytochrom_D1 PF02239.16 KDO18652.1 - 0.024 13.2 0.1 0.043 12.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain BTB_2 PF02214.22 KDO18653.1 - 4.1e-15 55.9 0.0 1.1e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF948 PF06103.11 KDO18653.1 - 1 9.7 6.5 7.1 7.0 3.0 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 KDO18653.1 - 3.5 7.6 8.3 0.82 9.7 1.3 3.0 3 0 0 3 3 3 0 Serine rich protein interaction domain Dimer_Tnp_hAT PF05699.14 KDO18654.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BTB_2 PF02214.22 KDO18655.1 - 1.8e-12 47.4 0.0 3.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 KDO18655.1 - 2.3e-06 27.7 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BTB_3 PF16017.5 KDO18655.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Dimer_Tnp_hAT PF05699.14 KDO18657.1 - 0.0066 16.2 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C3H2C3 PF17122.5 KDO18657.1 - 0.59 10.2 0.1 0.59 10.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger Metallothio_Euk PF12749.7 KDO18658.1 - 0.0053 16.9 55.6 38 4.5 55.6 2.6 1 1 0 1 1 1 1 Eukaryotic metallothionein Metallothio_PEC PF02068.16 KDO18658.1 - 0.12 12.7 53.0 0.17 12.3 32.9 2.5 1 1 1 2 2 2 0 Plant PEC family metallothionein MM_CoA_mutase PF01642.22 KDO18659.1 - 1.8e-235 782.4 0.1 2.1e-235 782.1 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KDO18659.1 - 1.5e-14 54.0 0.0 3.7e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain SNARE_assoc PF09335.11 KDO18660.1 - 3.2e-16 59.9 8.3 2.9e-14 53.6 7.7 2.2 2 0 0 2 2 2 2 SNARE associated Golgi protein Phage_holin_2_4 PF16082.5 KDO18660.1 - 0.03 14.0 0.2 0.065 13.0 0.1 1.6 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like TMEM223 PF14640.6 KDO18661.1 - 2.6e-11 44.0 0.1 4e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 223 BT1 PF03092.16 KDO18662.1 - 1.9e-11 42.9 5.7 1.9e-11 42.9 5.7 2.2 2 0 0 2 2 2 2 BT1 family Kinesin PF00225.23 KDO18663.1 - 4.5e-111 371.0 0.1 9e-110 366.7 0.0 2.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KDO18663.1 - 4.1e-22 78.7 0.0 1.5e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Bac_DnaA PF00308.18 KDO18663.1 - 0.0062 16.4 0.1 0.039 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein LUC7 PF03194.15 KDO18664.1 - 1.6e-78 263.9 1.5 2.2e-78 263.4 1.5 1.3 1 1 0 1 1 1 1 LUC7 N_terminus Mu-like_Pro PF10123.9 KDO18664.1 - 0.1 12.2 2.3 0.14 11.7 2.3 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF4897 PF16238.5 KDO18664.1 - 0.16 11.8 0.7 0.26 11.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) ADH_zinc_N PF00107.26 KDO18665.1 - 2.2e-16 60.0 0.6 4e-16 59.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO18665.1 - 5.2e-07 29.5 0.0 0.00032 20.5 0.0 2.7 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KDO18665.1 - 0.00037 21.5 0.2 0.0022 19.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Peripla_BP_4 PF13407.6 KDO18665.1 - 0.0036 16.9 0.4 0.0099 15.5 0.1 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain TrkA_N PF02254.18 KDO18665.1 - 0.0049 17.1 0.5 0.0099 16.1 0.5 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 KDO18665.1 - 0.014 15.3 0.2 0.025 14.5 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Histone PF00125.24 KDO18666.1 - 3.3e-19 69.5 0.2 4.2e-19 69.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KDO18666.1 - 0.00048 20.6 0.0 0.00082 19.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KDO18666.1 - 0.00067 19.9 0.1 0.0017 18.6 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KDO18666.1 - 0.0033 17.5 0.2 0.0039 17.2 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 KDO18666.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ADH_zinc_N PF00107.26 KDO18668.1 - 7.2e-19 68.0 1.0 1.4e-18 67.2 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO18668.1 - 4.8e-07 29.6 0.0 0.0002 21.2 0.0 3.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KDO18668.1 - 0.0016 18.7 0.4 0.0028 17.9 0.4 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 KDO18668.1 - 0.0016 18.4 0.3 0.0027 17.6 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N_2 PF13602.6 KDO18668.1 - 0.002 19.2 0.2 0.012 16.6 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KDO18668.1 - 0.0051 17.0 0.2 0.0099 16.1 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peripla_BP_4 PF13407.6 KDO18668.1 - 0.0051 16.4 0.4 0.016 14.8 0.4 1.8 1 1 0 1 1 1 1 Periplasmic binding protein domain NmrA PF05368.13 KDO18668.1 - 0.017 14.7 0.3 0.033 13.8 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family PGM_PMM_II PF02879.16 KDO18668.1 - 0.052 14.2 0.1 0.35 11.5 0.1 2.2 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CDT1_C PF16679.5 KDO18668.1 - 0.18 12.3 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain ADH_zinc_N PF00107.26 KDO18669.1 - 2.2e-11 43.9 0.2 3.8e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO18669.1 - 1.1e-06 28.5 0.0 3e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KDO18669.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KDO18669.1 - 0.0035 18.4 0.0 0.0069 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CDT1_C PF16679.5 KDO18669.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Nucleoside_tran PF01733.18 KDO18671.1 - 4.4e-07 29.6 0.1 4.7e-07 29.5 0.1 1.0 1 0 0 1 1 1 1 Nucleoside transporter Trehalase PF01204.18 KDO18672.1 - 4.1e-132 441.6 0.7 4.9e-132 441.4 0.7 1.0 1 0 0 1 1 1 1 Trehalase Nucleoside_tran PF01733.18 KDO18673.1 - 4e-19 69.1 14.0 1.3e-17 64.2 14.0 2.2 1 1 0 1 1 1 1 Nucleoside transporter TssO PF17561.2 KDO18673.1 - 0.17 12.0 0.5 0.36 10.9 0.5 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF5090 PF17009.5 KDO18673.1 - 0.29 11.1 2.5 0.67 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) UQ_con PF00179.26 KDO18674.1 - 4.1e-10 39.5 0.0 7.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TIM PF00121.18 KDO18676.1 - 2.8e-81 272.5 0.3 4.1e-81 271.9 0.3 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_C PF02800.20 KDO18676.1 - 8.3e-69 230.2 0.0 1.6e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KDO18676.1 - 3.6e-35 120.3 0.0 8.2e-35 119.2 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KDO18676.1 - 0.016 15.4 0.2 0.099 12.8 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Syntaxin-18_N PF10496.9 KDO18678.1 - 0.029 14.6 0.3 0.05 13.8 0.3 1.3 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus PLAC8 PF04749.17 KDO18682.1 - 3.5e-19 69.6 20.1 6.3e-19 68.8 20.1 1.4 1 0 0 1 1 1 1 PLAC8 family LPMO_10 PF03067.15 KDO18683.1 - 3.9e-21 76.6 0.5 3.9e-21 76.6 0.5 2.0 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_1 PF00734.18 KDO18683.1 - 1.8e-10 40.6 5.1 6.5e-10 38.8 5.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO18683.1 - 2.6e-09 36.5 35.4 8.9e-06 25.2 14.4 3.2 1 1 2 3 3 3 2 PT repeat DUF4106 PF13388.6 KDO18683.1 - 0.0043 16.4 11.8 0.0063 15.8 11.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Glycoprotein_G PF00802.19 KDO18683.1 - 0.38 10.1 17.1 0.68 9.2 17.1 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G LPMO_10 PF03067.15 KDO18684.1 - 1.3e-23 84.7 0.7 1.9e-23 84.2 0.0 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_1 PF00734.18 KDO18684.1 - 1.9e-11 43.7 8.3 6.7e-11 41.9 8.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain MGC-24 PF05283.11 KDO18684.1 - 1.7 9.1 7.5 0.26 11.7 3.0 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trypan_PARP PF05887.11 KDO18684.1 - 3 7.8 10.2 0.62 10.0 4.4 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 KDO18684.1 - 3.1 6.9 4.7 4.6 6.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MMR_HSR1 PF01926.23 KDO18685.1 - 0.00045 20.3 0.0 0.0014 18.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lipase_3 PF01764.25 KDO18685.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO18685.1 - 0.0085 16.7 6.1 0.072 13.7 0.1 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Dynamin_N PF00350.23 KDO18685.1 - 0.032 14.3 0.0 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DUF2974 PF11187.8 KDO18685.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CBM_20 PF00686.19 KDO18686.1 - 1.3e-15 57.1 0.0 4e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain cNMP_binding PF00027.29 KDO18686.1 - 1.3e-12 47.6 0.0 3.2e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain F5_F8_type_C PF00754.25 KDO18686.1 - 0.00012 22.2 0.0 0.0005 20.2 0.0 1.9 1 1 0 1 1 1 1 F5/8 type C domain UBM PF14377.6 KDO18686.1 - 0.092 12.2 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Ras PF00071.22 KDO18687.1 - 3.2e-54 182.9 0.0 4.1e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO18687.1 - 2.3e-29 102.0 0.0 3.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO18687.1 - 1.5e-15 57.1 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO18687.1 - 3.2e-05 23.5 0.1 0.0001 21.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KDO18687.1 - 7.3e-05 22.7 0.1 0.049 13.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KDO18687.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KDO18687.1 - 0.00041 19.8 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO18687.1 - 0.00074 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO18687.1 - 0.0032 17.0 0.1 0.018 14.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KDO18687.1 - 0.0035 17.1 0.0 0.0086 15.8 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KDO18687.1 - 0.029 14.7 0.1 0.057 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Bac_DnaA PF00308.18 KDO18687.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial dnaA protein DLIC PF05783.11 KDO18687.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_18 PF13238.6 KDO18687.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KDO18687.1 - 0.17 11.8 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Frag1 PF10277.9 KDO18688.1 - 2.4e-14 53.4 17.8 3.4e-14 52.9 17.8 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2298 PF10060.9 KDO18688.1 - 0.00082 18.2 4.2 0.0011 17.7 4.2 1.2 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) DUF4231 PF14015.6 KDO18688.1 - 0.28 11.7 2.9 0.41 11.1 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Cyt_bd_oxida_II PF02322.15 KDO18688.1 - 0.35 10.2 14.3 0.8 9.0 9.7 2.3 2 1 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Aminotran_5 PF00266.19 KDO18689.1 - 1.2e-22 80.4 0.1 1.4e-22 80.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Mito_carr PF00153.27 KDO18690.1 - 5.2e-64 212.2 1.8 2.7e-21 75.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ELMO_CED12 PF04727.13 KDO18692.1 - 7.9e-24 84.7 0.0 1.2e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Cellulase PF00150.18 KDO18694.1 - 4e-24 85.5 0.0 5.6e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KDO18695.1 - 2e-25 89.8 0.0 2.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Band_7 PF01145.25 KDO18697.1 - 1.2e-22 80.8 0.0 1.2e-22 80.8 0.0 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF3629 PF12302.8 KDO18697.1 - 0.004 16.6 2.5 0.0088 15.5 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3629) DUF4058 PF13267.6 KDO18697.1 - 0.4 10.1 9.1 0.025 14.0 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4058) FYVE PF01363.21 KDO18698.1 - 6.4e-17 61.5 10.2 1.2e-16 60.6 10.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO18698.1 - 3.8e-10 40.5 0.0 8.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO18698.1 - 1.5e-05 25.3 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain zf-RING_5 PF14634.6 KDO18698.1 - 5 7.2 10.4 14 5.7 10.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Ank_2 PF12796.7 KDO18699.1 - 1.8e-65 217.5 27.2 2.7e-14 53.5 0.2 7.9 4 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO18699.1 - 8.1e-45 150.3 30.3 3.7e-10 39.8 0.2 12.7 6 4 9 15 15 15 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO18699.1 - 2.7e-43 145.8 22.1 6.6e-08 32.9 0.1 10.7 7 4 2 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18699.1 - 2.9e-37 122.4 21.7 0.0037 17.7 0.0 16.7 17 0 0 17 17 17 7 Ankyrin repeat Pkinase PF00069.25 KDO18699.1 - 2.9e-37 128.5 0.0 5.3e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18699.1 - 7.5e-35 120.5 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KDO18699.1 - 1.3e-23 82.4 42.6 9.8e-05 22.6 0.1 13.7 15 1 1 16 16 16 5 Ankyrin repeat Kdo PF06293.14 KDO18699.1 - 0.0064 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin_5 PF13743.6 KDO18699.1 - 0.083 12.6 0.5 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin Phage_T7_Capsid PF05396.11 KDO18699.1 - 0.19 12.1 0.5 2.3 8.6 0.2 2.7 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Ank_2 PF12796.7 KDO18700.1 - 8e-96 314.8 29.4 1.4e-15 57.6 2.2 10.2 4 2 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18700.1 - 2e-82 270.5 18.0 1.3e-12 47.9 0.2 13.6 7 4 7 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18700.1 - 4e-77 244.9 15.3 0.00073 19.8 0.0 21.6 22 0 0 22 22 22 16 Ankyrin repeat Ank_5 PF13857.6 KDO18700.1 - 1.6e-66 219.5 36.4 4.3e-10 39.6 0.1 15.8 5 4 11 17 17 17 13 Ankyrin repeats (many copies) Ank PF00023.30 KDO18700.1 - 1.6e-59 195.9 48.0 6.4e-05 23.2 0.1 19.5 21 0 0 21 21 21 14 Ankyrin repeat Pkinase PF00069.25 KDO18700.1 - 7.1e-37 127.2 0.0 1.4e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18700.1 - 6.8e-35 120.6 0.0 1.1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18700.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO18700.1 - 0.0024 17.3 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SEP PF08059.13 KDO18700.1 - 0.17 12.5 0.0 51 4.5 0.0 3.0 2 0 0 2 2 2 0 SEP domain Cellulase PF00150.18 KDO18701.1 - 5.2e-18 65.5 0.0 7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GHL10 PF02638.15 KDO18703.1 - 0.077 12.1 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 DSPc PF00782.20 KDO18704.1 - 8.2e-07 28.9 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KDO18704.1 - 0.049 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF4139 PF13598.6 KDO18705.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) DUF3130 PF11328.8 KDO18706.1 - 0.25 11.6 0.9 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 WD40 PF00400.32 KDO18713.1 - 2.5e-33 113.6 26.5 1.4e-06 28.9 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO18713.1 - 1.1e-11 44.8 0.2 0.22 11.8 0.0 5.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO18713.1 - 0.002 17.5 0.2 0.53 9.5 0.1 2.9 1 1 1 2 2 2 2 WD40-like domain PPR_2 PF13041.6 KDO18714.1 - 1.3e-06 28.4 0.0 0.018 15.2 0.0 2.7 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.20 KDO18714.1 - 4.8e-06 26.4 0.2 0.12 12.7 0.0 3.1 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 KDO18714.1 - 1.6e-05 24.9 0.0 0.00099 19.1 0.0 2.9 2 1 1 3 3 3 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KDO18714.1 - 0.00013 21.6 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_long PF17177.4 KDO18714.1 - 0.0094 15.3 0.2 0.02 14.3 0.2 1.6 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Herpes_BBRF1 PF04793.12 KDO18714.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 BRRF1-like protein AAA PF00004.29 KDO18715.1 - 1e-12 48.6 0.2 1.7e-12 47.9 0.2 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KDO18715.1 - 1.3e-12 47.8 0.1 2.4e-10 40.4 0.6 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KDO18715.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO18715.1 - 2.5e-06 28.0 0.0 0.00015 22.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO18715.1 - 2.6e-05 24.0 0.1 0.00013 21.8 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KDO18715.1 - 5.4e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KDO18715.1 - 0.00011 22.5 0.2 0.06 13.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KDO18715.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KDO18715.1 - 0.00053 19.8 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KDO18715.1 - 0.001 18.5 0.0 0.031 13.7 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0020 PF01170.18 KDO18715.1 - 0.0031 17.2 0.0 0.012 15.3 0.0 1.9 3 0 0 3 3 3 1 Putative RNA methylase family UPF0020 AAA_19 PF13245.6 KDO18715.1 - 0.0034 17.7 0.4 0.013 15.8 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KDO18715.1 - 0.0045 16.9 0.1 0.0078 16.1 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KDO18715.1 - 0.0059 16.4 0.1 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KDO18715.1 - 0.01 15.8 0.4 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 NTPase TniB PF05621.11 KDO18715.1 - 0.012 15.0 0.1 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KDO18715.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KDO18715.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KDO18715.1 - 0.024 14.4 0.4 1.9 8.2 0.0 2.6 2 1 1 3 3 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KDO18715.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KDO18715.1 - 0.044 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KDO18715.1 - 0.054 13.2 0.3 0.19 11.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO18715.1 - 0.074 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KDO18715.1 - 0.089 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_18 PF13238.6 KDO18715.1 - 0.16 12.5 0.1 0.36 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KDO18715.1 - 0.24 10.6 0.3 3.1 6.9 0.3 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_C PF00271.31 KDO18716.1 - 9.3e-19 67.8 0.1 7.4e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 KDO18716.1 - 1.1e-07 31.6 5.7 1.1e-07 31.6 5.7 3.0 3 0 0 3 3 3 1 PHD-finger Rtf2 PF04641.12 KDO18716.1 - 3.1e-06 26.8 7.4 3.1e-06 26.8 7.4 2.6 3 0 0 3 3 3 1 Rtf2 RING-finger HDA2-3 PF11496.8 KDO18716.1 - 0.01 15.0 0.0 0.01 15.0 0.0 2.6 1 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Cys_rich_CPCC PF14206.6 KDO18716.1 - 0.029 14.2 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 Cysteine-rich CPCC DUF5076 PF16826.5 KDO18716.1 - 0.094 12.7 0.6 0.26 11.2 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) HIP1_clath_bdg PF16515.5 KDO18717.1 - 0.011 16.4 5.1 0.011 16.4 5.1 9.6 2 1 7 10 10 10 0 Clathrin-binding domain of Huntingtin-interacting protein 1 adh_short PF00106.25 KDO18718.1 - 2.5e-26 92.4 0.6 2.5e-25 89.1 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO18718.1 - 4.8e-20 72.1 0.3 2.9e-10 40.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KDO18718.1 - 0.0016 18.4 0.2 0.0052 16.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KDO18718.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KDO18718.1 - 0.031 13.8 0.1 0.057 13.0 0.1 1.4 2 0 0 2 2 2 0 NmrA-like family HTH_Tnp_IS1 PF12759.7 KDO18718.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 InsA C-terminal domain RmlD_sub_bind PF04321.17 KDO18718.1 - 0.038 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KDO18719.1 - 3.4e-27 95.2 0.8 4.6e-27 94.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO18719.1 - 6.8e-25 88.0 1.3 8.1e-25 87.7 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KDO18719.1 - 9.9e-07 28.8 0.3 1.5e-06 28.2 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KDO18719.1 - 0.0023 17.5 0.1 0.0034 17.0 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KDO18719.1 - 0.0036 16.4 0.1 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 KDO18719.1 - 0.0072 15.8 0.1 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KDO18719.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase SDF PF00375.18 KDO18720.1 - 6.2e-13 48.5 4.3 8e-13 48.2 4.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Gly-zipper_Omp PF13488.6 KDO18720.1 - 0.0028 17.6 0.6 0.0051 16.8 0.6 1.4 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 KDO18720.1 - 0.04 13.8 1.6 0.078 12.9 1.6 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF3482 PF11981.8 KDO18720.1 - 0.078 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Cyclin_N PF00134.23 KDO18721.1 - 2.2e-09 37.1 0.0 3.3e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.7 KDO18723.1 - 2.1e-52 175.6 11.1 3e-17 63.0 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18723.1 - 1.2e-41 140.5 11.3 9.1e-14 51.6 0.2 8.0 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18723.1 - 1.3e-35 117.4 21.1 8.4e-05 22.7 0.1 11.0 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 KDO18723.1 - 1e-31 108.0 34.2 1e-05 25.8 0.7 10.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KDO18723.1 - 1.5e-28 98.5 23.6 1.2e-07 31.9 0.3 7.5 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ub-Mut7C PF14451.6 KDO18723.1 - 0.13 12.1 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin ACT PF01842.25 KDO18723.1 - 1 9.2 3.3 4.5 7.1 0.0 3.5 5 0 0 5 5 5 0 ACT domain WD40 PF00400.32 KDO18726.1 - 1.7e-26 91.9 15.8 1.2e-06 29.1 0.0 8.3 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO18726.1 - 3.9e-17 62.3 0.0 0.0018 18.5 0.0 6.2 2 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO18726.1 - 3.1e-05 23.1 0.2 0.28 10.1 0.1 4.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KDO18726.1 - 0.0006 18.5 0.8 0.77 8.2 0.1 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain DUF1513 PF07433.11 KDO18726.1 - 0.0043 16.2 0.0 0.17 11.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) PD40 PF07676.12 KDO18726.1 - 0.012 15.5 1.4 45 4.2 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KDO18726.1 - 0.094 12.0 0.0 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 KDO18726.1 - 0.73 10.4 6.3 8.4 7.0 0.2 4.7 4 1 1 5 5 5 0 PQQ-like domain Proteasome_A_N PF10584.9 KDO18726.1 - 1.5 8.5 6.9 1.8 8.3 0.0 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature AMP-binding PF00501.28 KDO18730.1 - 9.2e-84 281.5 0.0 1.1e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 KDO18731.1 - 3.7e-67 226.5 0.0 4.3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18731.1 - 4.8e-22 78.5 0.0 1.2e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KDO18731.1 - 3.4e-08 33.7 0.0 4.3e-06 26.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO18731.1 - 0.00082 18.3 0.1 0.0027 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO18731.1 - 0.0041 16.5 1.4 0.0071 15.7 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO18731.1 - 0.017 14.8 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_C1 PF00112.23 KDO18732.1 - 1.3e-05 25.4 0.5 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Acetyltransf_10 PF13673.7 KDO18734.1 - 2.4e-15 56.6 0.0 3.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO18734.1 - 2.9e-06 27.6 0.0 4.3e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO18734.1 - 2.2e-05 24.7 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KDO18734.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein PLAC8 PF04749.17 KDO18735.1 - 7.2e-10 39.8 1.2 1.3e-09 38.9 1.2 1.4 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.17 KDO18739.1 - 9e-38 130.0 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18739.1 - 4.2e-35 121.4 0.0 6.2e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO18739.1 - 0.0003 20.2 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO18739.1 - 0.0025 17.2 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO18739.1 - 0.087 11.8 0.0 9.5 5.0 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain EphA2_TM PF14575.6 KDO18739.1 - 0.14 13.0 0.0 0.28 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Homeodomain PF00046.29 KDO18741.1 - 2.2e-05 24.2 6.8 0.026 14.3 0.3 3.2 3 2 0 3 3 3 2 Homeodomain DUF4456 PF14644.6 KDO18741.1 - 0.015 15.0 2.6 3.2 7.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) Ldi PF18566.1 KDO18741.1 - 0.41 10.1 1.6 0.54 9.7 0.1 1.8 2 0 0 2 2 2 0 Linalool dehydratase/isomerase CRISPR_Cse2 PF09485.10 KDO18741.1 - 4.3 7.9 5.7 8.3 6.9 0.4 2.8 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Aldo_ket_red PF00248.21 KDO18742.1 - 9.3e-70 235.1 0.0 1e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Taxilin PF09728.9 KDO18743.1 - 0.0023 17.1 0.6 0.0049 16.1 0.2 1.7 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Fez1 PF06818.15 KDO18743.1 - 0.033 14.7 3.8 0.067 13.6 3.8 1.5 1 0 0 1 1 1 0 Fez1 PBP1_TM PF14812.6 KDO18743.1 - 0.07 13.5 4.9 0.055 13.8 2.1 2.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KDO18743.1 - 0.1 12.3 5.7 0.13 11.9 5.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2203 PF09969.9 KDO18743.1 - 0.22 12.3 3.4 1.5 9.5 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Jnk-SapK_ap_N PF09744.9 KDO18743.1 - 0.97 9.6 10.7 3.1 8.0 4.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 KDO18743.1 - 1.1 8.8 5.8 0.52 9.9 2.7 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 NOA36 PF06524.12 KDO18743.1 - 2.4 7.4 5.7 3.7 6.8 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein Lebercilin PF15619.6 KDO18743.1 - 4 7.1 12.2 16 5.1 12.2 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Aldo_ket_red PF00248.21 KDO18744.1 - 4e-54 183.8 0.0 4.8e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KDO18745.1 - 1.4e-72 244.4 0.0 1.5e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBM_1 PF00734.18 KDO18746.1 - 0.00019 21.3 11.2 0.00019 21.3 11.2 4.5 6 1 0 6 6 6 1 Fungal cellulose binding domain Peptidase_M14 PF00246.24 KDO18747.1 - 3.8e-38 131.9 0.0 5.3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Cyclin_N PF00134.23 KDO18747.1 - 2.2e-13 50.1 1.5 3.7e-13 49.3 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO18747.1 - 0.0062 16.6 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Acyltransferase PF01553.21 KDO18748.1 - 8.2e-15 54.6 0.0 1.8e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Glycos_trans_3N PF02885.17 KDO18748.1 - 0.084 12.7 0.6 1.3 8.9 0.1 2.8 2 1 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Disintegrin PF00200.23 KDO18750.1 - 3.3e-20 72.6 64.8 2.1e-05 25.2 14.4 6.2 4 3 1 5 5 5 5 Disintegrin Atg14 PF10186.9 KDO18751.1 - 7.9e-05 21.9 10.4 7.9e-05 21.9 10.4 2.0 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 NRBF2 PF08961.10 KDO18751.1 - 0.00063 19.4 4.0 0.0014 18.2 4.0 1.7 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Filament PF00038.21 KDO18751.1 - 0.00076 19.1 12.4 0.0015 18.2 12.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein Spc29 PF17082.5 KDO18751.1 - 0.016 15.0 4.0 0.04 13.8 4.0 1.7 1 0 0 1 1 1 0 Spindle Pole Component 29 VirD1 PF07328.11 KDO18751.1 - 0.042 13.8 0.2 0.11 12.5 0.0 1.8 2 0 0 2 2 1 0 T-DNA border endonuclease VirD1 DUF4140 PF13600.6 KDO18751.1 - 0.061 13.8 20.4 0.12 12.8 4.0 2.9 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) USP8_interact PF08941.10 KDO18751.1 - 0.067 13.0 8.9 0.099 12.5 6.2 2.1 1 1 1 2 2 2 0 USP8 interacting Mto2_bdg PF12808.7 KDO18751.1 - 0.22 11.9 4.3 7.1 7.0 0.2 3.6 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4763 PF15960.5 KDO18751.1 - 0.24 10.6 11.5 0.045 13.1 7.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 KDO18751.1 - 0.25 10.2 17.0 1.3 7.9 17.1 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KDO18751.1 - 0.36 11.3 13.9 0.34 11.3 12.0 1.9 1 1 1 2 2 2 0 Fez1 DUF2353 PF09789.9 KDO18751.1 - 0.51 9.7 14.4 1.7 7.9 14.4 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Phage_GP20 PF06810.11 KDO18751.1 - 0.59 9.9 14.5 0.87 9.4 12.5 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 KDO18751.1 - 0.65 9.2 10.0 1 8.5 10.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KDO18751.1 - 0.76 9.6 18.6 2.3 8.1 13.3 3.1 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 KDO18751.1 - 1.1 9.4 20.0 0.038 14.1 10.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 KDO18751.1 - 1.2 7.6 10.0 1.7 7.1 10.0 1.2 1 0 0 1 1 1 0 Macoilin family DUF5339 PF17274.2 KDO18751.1 - 1.8 9.5 17.3 11 7.0 8.4 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5339) V_ATPase_I PF01496.19 KDO18751.1 - 1.9 6.3 4.5 2.4 6.0 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 KDO18751.1 - 2 8.8 15.6 1.4 9.3 9.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KDO18751.1 - 2.6 8.1 22.6 0.042 13.9 7.7 3.2 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CdvA PF18822.1 KDO18751.1 - 3.2 7.6 15.2 4.1 7.2 4.4 2.9 2 1 0 3 3 3 0 CdvA-like coiled-coil domain ADIP PF11559.8 KDO18751.1 - 4.2 7.4 18.9 0.72 9.9 13.4 2.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KDO18751.1 - 8.6 5.6 15.1 8.2 5.7 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KDO18751.1 - 8.8 6.9 20.7 55 4.3 0.7 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region FAM76 PF16046.5 KDO18751.1 - 9.5 5.5 9.4 14 4.9 9.4 1.2 1 0 0 1 1 1 0 FAM76 protein Sin_N PF04801.13 KDO18752.1 - 5.9e-66 223.4 0.1 1.1e-65 222.6 0.1 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region DnaJ PF00226.31 KDO18753.1 - 8.8e-22 77.0 0.5 2.3e-21 75.7 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain WW PF00397.26 KDO18754.1 - 3.3e-07 30.3 1.3 5.1e-07 29.7 1.3 1.3 1 0 0 1 1 1 1 WW domain Cytochrom_c3_2 PF14537.6 KDO18754.1 - 0.0075 16.7 0.9 0.012 16.0 0.1 1.8 2 0 0 2 2 2 1 Cytochrome c3 Cytochrome_C7 PF14522.6 KDO18754.1 - 0.055 13.5 1.2 0.34 10.9 1.3 2.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-RING_7 PF02591.15 KDO18754.1 - 0.062 13.5 0.2 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain FUN14 PF04930.15 KDO18755.1 - 6.8e-23 80.9 0.4 1e-22 80.3 0.4 1.3 1 0 0 1 1 1 1 FUN14 family Dockerin_1 PF00404.18 KDO18755.1 - 0.016 15.4 0.5 0.029 14.5 0.5 1.4 1 0 0 1 1 1 0 Dockerin type I domain SoDot-IcmSS PF16848.5 KDO18755.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative EF-hand_6 PF13405.6 KDO18755.1 - 0.091 12.7 0.3 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain Cas_CT1975 PF09344.10 KDO18755.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 CT1975-like protein YqzM PF14141.6 KDO18755.1 - 0.16 12.0 1.0 0.77 9.9 0.0 2.3 3 0 0 3 3 3 0 YqzM-like protein Ndc1_Nup PF09531.10 KDO18756.1 - 1 7.9 5.4 1.1 7.8 5.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3040 PF11239.8 KDO18756.1 - 1.6 9.1 3.8 16 5.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Ank_4 PF13637.6 KDO18757.1 - 0.043 14.4 0.1 0.29 11.8 0.1 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) APG6 PF04111.12 KDO18758.1 - 1.3e-59 201.1 0.0 1.8e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain zf-C2H2_8 PF15909.5 KDO18758.1 - 0.044 14.1 0.4 0.077 13.3 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon NIL PF09383.10 KDO18758.1 - 0.12 12.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 NIL domain Ank_2 PF12796.7 KDO18760.1 - 6.4e-22 78.0 25.5 4.6e-08 33.5 0.7 6.3 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18760.1 - 7.2e-14 52.0 21.0 0.00048 20.6 0.0 7.7 6 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18760.1 - 4.9e-09 36.3 17.5 0.31 11.4 0.1 8.2 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18760.1 - 5e-09 35.7 22.0 2.6 8.9 0.1 11.3 10 2 2 12 12 12 3 Ankyrin repeat Ank PF00023.30 KDO18760.1 - 0.34 11.4 17.8 5.7 7.6 0.0 7.5 6 4 0 6 6 6 0 Ankyrin repeat TPH PF13868.6 KDO18761.1 - 1.6e-29 102.6 78.7 1.6e-29 102.6 78.7 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Elong_Iki1 PF10483.9 KDO18762.1 - 8.8e-10 38.6 0.0 2.3e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Elongator subunit Iki1 Aa_trans PF01490.18 KDO18763.1 - 3e-14 52.5 22.5 4.4e-14 52.0 22.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_8 PF13855.6 KDO18764.1 - 6.9e-22 77.0 18.0 9e-11 41.4 3.4 4.4 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KDO18764.1 - 7.4e-20 70.7 23.7 1.5e-05 25.3 0.4 6.5 3 1 6 9 9 9 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO18764.1 - 7.3e-07 28.9 8.5 0.0035 16.9 1.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KDO18764.1 - 3.8e-06 26.9 0.1 0.068 13.1 0.1 3.1 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KDO18764.1 - 0.00028 21.0 15.4 2.8 8.8 0.2 7.7 7 2 0 7 7 7 1 Leucine Rich Repeat CREPT PF16566.5 KDO18764.1 - 0.066 13.4 0.5 8.6 6.5 0.1 3.0 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour LRR_6 PF13516.6 KDO18764.1 - 2.1 8.6 20.1 1.4 9.2 0.2 6.1 7 0 0 7 7 7 0 Leucine Rich repeat DUF4800 PF16057.5 KDO18766.1 - 0.64 9.2 2.1 0.61 9.3 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Globin PF00042.22 KDO18768.1 - 0.0042 17.6 2.6 0.037 14.6 2.6 2.3 1 1 0 1 1 1 1 Globin Lipocalin_4 PF13648.6 KDO18770.1 - 0.11 13.5 1.1 0.4 11.7 1.1 1.9 1 1 0 1 1 1 0 Lipocalin-like domain DUF281 PF03436.13 KDO18770.1 - 0.79 10.2 5.7 2.7 8.5 5.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF281) Ank_2 PF12796.7 KDO18773.1 - 1.6e-73 243.3 26.8 2.6e-11 43.9 0.6 11.3 4 3 5 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18773.1 - 3.9e-53 177.2 35.8 6.2e-06 26.7 0.1 15.2 9 4 7 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18773.1 - 2.2e-52 168.9 41.8 0.00075 19.8 0.0 21.2 23 0 0 23 23 23 12 Ankyrin repeat Ank_5 PF13857.6 KDO18773.1 - 8.6e-41 137.5 53.8 6.6e-08 32.7 0.8 15.2 7 6 11 18 18 18 11 Ankyrin repeats (many copies) Ank PF00023.30 KDO18773.1 - 5.3e-39 131.0 50.5 0.00051 20.4 0.9 17.0 19 0 0 19 19 19 10 Ankyrin repeat MadL PF03817.13 KDO18773.1 - 0.23 11.5 0.6 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Malonate transporter MadL subunit ScsC_N PF18312.1 KDO18773.1 - 0.58 10.0 3.1 41 4.1 0.1 3.6 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain Pkinase_Tyr PF07714.17 KDO18774.1 - 9.3e-25 87.4 0.0 1.1e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18774.1 - 8.9e-22 77.7 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Elicitin PF00964.17 KDO18775.1 - 0.0014 18.7 1.0 0.0014 18.7 1.0 5.8 6 1 0 6 6 6 2 Elicitin FeS PF04060.13 KDO18775.1 - 0.0033 17.1 3.1 2.9 7.6 0.2 3.6 2 0 0 2 2 2 2 Putative Fe-S cluster FNIP_M PF14637.6 KDO18775.1 - 0.02 14.9 0.0 8 6.4 0.0 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain NADH_4Fe-4S PF10589.9 KDO18775.1 - 0.049 13.7 5.0 1.2 9.2 0.4 3.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Phytochelatin PF05023.14 KDO18775.1 - 0.23 10.7 3.7 6.6 5.9 0.2 2.6 2 1 0 2 2 2 0 Phytochelatin synthase NfrA_C PF13283.6 KDO18775.1 - 0.28 10.7 1.1 4.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term Lipocalin_4 PF13648.6 KDO18775.1 - 0.81 10.7 3.5 0.69 10.9 0.4 2.5 2 0 0 2 2 2 0 Lipocalin-like domain UCH PF00443.29 KDO18777.1 - 1e-42 146.4 0.0 1.5e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO18777.1 - 3e-31 109.2 0.4 1.1e-30 107.3 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KDO18777.1 - 0.0013 18.3 1.0 0.29 10.6 1.0 3.3 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase p450 PF00067.22 KDO18778.1 - 5.8e-23 81.4 0.0 6.4e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trm112p PF03966.16 KDO18779.1 - 0.27 11.8 3.4 7.4 7.2 0.0 3.2 3 1 0 3 3 3 0 Trm112p-like protein RMP PF14996.6 KDO18780.1 - 8.1e-41 139.8 10.1 8.1e-41 139.8 10.1 1.7 1 1 1 2 2 2 1 Retinal Maintenance Pet191_N PF10203.9 KDO18781.1 - 3.8e-23 81.5 9.0 4.3e-23 81.4 9.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 cNMP_binding PF00027.29 KDO18782.1 - 4.4e-16 58.7 0.1 8e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO18782.1 - 3.8e-15 55.8 4.2 6e-15 55.1 4.2 1.3 1 0 0 1 1 1 1 Ion transport protein DUF2281 PF10047.9 KDO18782.1 - 0.17 12.6 0.6 8.5 7.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2281) DNA_ligase_A_M PF01068.21 KDO18783.1 - 6.7e-44 150.0 0.0 1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KDO18783.1 - 1.6e-24 87.1 0.2 2.9e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KDO18783.1 - 4.7e-24 84.9 0.0 1.9e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KDO18783.1 - 5.5e-09 36.5 0.0 8.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KDO18783.1 - 1.9e-05 24.6 0.0 4.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.6 KDO18783.1 - 0.02 14.9 0.3 0.7 10.0 0.0 2.9 3 0 0 3 3 3 0 DNA ligase OB-like domain PhnI PF05861.12 KDO18783.1 - 0.042 12.7 0.1 0.064 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Pkinase_Tyr PF07714.17 KDO18784.1 - 3.1e-22 79.1 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18784.1 - 5.9e-14 52.1 0.0 1.3e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain F-box PF00646.33 KDO18784.1 - 0.0032 17.3 0.0 0.038 13.9 0.0 2.4 2 0 0 2 2 2 1 F-box domain Terminase_6 PF03237.15 KDO18785.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family Pkinase_Tyr PF07714.17 KDO18786.1 - 1.9e-19 69.9 0.0 6.6e-19 68.2 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18786.1 - 4.7e-13 49.1 0.0 8.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF4690 PF15756.5 KDO18786.1 - 0.6 10.7 4.8 1.7 9.3 4.8 1.8 1 1 0 1 1 1 0 Small Novel Rich in Cartilage MGC-24 PF05283.11 KDO18786.1 - 1.6 9.2 10.5 0.12 12.9 1.1 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MSA-2c PF12238.8 KDO18786.1 - 1.8 8.5 6.8 3.8 7.5 6.8 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF1180 PF06679.12 KDO18786.1 - 3.2 8.2 6.6 15 6.0 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 KDO18787.1 - 6.9e-26 91.2 0.0 9.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18787.1 - 5.3e-24 84.9 0.0 8.2e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 KDO18787.1 - 4.8 6.7 9.6 11 5.5 9.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase_Tyr PF07714.17 KDO18788.1 - 5e-25 88.3 0.0 1.1e-24 87.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18788.1 - 2.2e-19 69.9 0.0 3.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MHYT PF03707.16 KDO18788.1 - 0.0055 16.8 0.1 0.018 15.2 0.1 1.9 1 0 0 1 1 1 1 Bacterial signalling protein N terminal repeat LRR_4 PF12799.7 KDO18788.1 - 0.019 15.4 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 KDO18788.1 - 0.15 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family MGC-24 PF05283.11 KDO18788.1 - 0.35 11.3 7.6 0.046 14.2 2.4 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1180 PF06679.12 KDO18788.1 - 3 8.2 5.3 5.1 7.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) VWA_N2 PF16164.5 KDO18788.1 - 3.8 7.7 6.6 10 6.4 6.6 1.7 1 0 0 1 1 1 0 VWA N-terminal zf-RING_2 PF13639.6 KDO18789.1 - 3.4e-14 52.9 7.5 5.6e-14 52.2 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 KDO18789.1 - 4.1e-14 52.4 0.1 6.9e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KDO18789.1 - 2.2e-10 40.6 4.6 5.6e-10 39.3 4.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO18789.1 - 2.8e-09 36.7 7.2 5e-09 35.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO18789.1 - 7.9e-09 35.1 6.2 9.7e-09 34.8 2.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KDO18789.1 - 3.6e-08 32.9 4.4 9.1e-08 31.6 4.4 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KDO18789.1 - 4.5e-07 29.6 6.1 4.5e-07 29.6 6.1 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO18789.1 - 1.4e-06 28.0 5.5 1.4e-06 28.0 5.5 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO18789.1 - 2.5e-05 24.1 5.6 4.5e-05 23.3 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO18789.1 - 3.5e-05 23.6 7.0 6.1e-05 22.8 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO18789.1 - 3.7e-05 23.7 2.0 7.6e-05 22.7 2.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO18789.1 - 5e-05 23.2 0.9 5e-05 23.2 0.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.11 KDO18789.1 - 0.0086 16.4 7.6 0.015 15.6 7.6 1.4 1 0 0 1 1 1 1 RING-like domain FANCL_C PF11793.8 KDO18789.1 - 0.013 15.7 6.0 0.12 12.6 6.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KDO18789.1 - 0.021 14.9 7.6 0.05 13.7 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KDO18789.1 - 0.048 13.7 3.8 0.12 12.5 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_10 PF16685.5 KDO18789.1 - 0.086 13.0 3.7 0.15 12.2 3.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zf_RING PF16744.5 KDO18789.1 - 0.16 12.1 4.8 0.66 10.1 4.9 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 KDO18789.1 - 0.47 10.7 7.6 0.16 12.3 3.5 2.2 2 1 1 3 3 3 0 PHD-like zinc-binding domain zf-RING_4 PF14570.6 KDO18789.1 - 0.75 9.6 4.3 1.5 8.7 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KDO18789.1 - 1.2 9.0 5.8 2.9 7.9 5.8 1.7 1 1 0 1 1 1 0 PHD-finger EMP24_GP25L PF01105.24 KDO18790.1 - 2.7e-35 122.0 0.0 3.1e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AKNA PF12443.8 KDO18790.1 - 0.0082 16.8 1.1 0.4 11.3 0.2 2.2 2 0 0 2 2 2 1 AT-hook-containing transcription factor DUF5519 PF17648.1 KDO18790.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) AAA PF00004.29 KDO18791.1 - 1.1e-54 184.4 0.0 1.5e-43 148.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO18791.1 - 1.1e-11 45.4 1.3 0.0019 18.6 0.4 4.2 3 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KDO18791.1 - 4.1e-08 33.1 0.0 6.4e-05 22.8 0.0 3.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO18791.1 - 4.4e-06 26.7 0.1 0.044 13.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KDO18791.1 - 2.2e-05 25.0 0.0 0.00073 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO18791.1 - 2.6e-05 24.0 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KDO18791.1 - 3.5e-05 23.4 0.0 0.044 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 KDO18791.1 - 4.2e-05 23.5 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KDO18791.1 - 9.9e-05 22.6 0.1 0.014 15.7 0.1 3.3 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 KDO18791.1 - 0.00026 20.3 0.0 0.054 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Vps4_C PF09336.10 KDO18791.1 - 0.00032 20.6 0.0 0.0012 18.8 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 KDO18791.1 - 0.00057 19.2 0.0 0.0039 16.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 KDO18791.1 - 0.00087 19.0 1.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_14 PF13173.6 KDO18791.1 - 0.0011 19.1 0.0 0.14 12.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KDO18791.1 - 0.0013 19.1 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KDO18791.1 - 0.0013 18.2 0.1 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KDO18791.1 - 0.0018 17.4 0.0 0.46 9.5 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 KDO18791.1 - 0.0032 17.4 0.1 0.55 10.1 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 KDO18791.1 - 0.0035 17.1 0.1 0.15 11.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KDO18791.1 - 0.0048 16.3 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 KaiC Parvo_NS1 PF01057.17 KDO18791.1 - 0.0053 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KDO18791.1 - 0.0059 16.8 0.0 0.1 12.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KDO18791.1 - 0.0067 16.2 0.0 0.26 11.0 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KDO18791.1 - 0.0073 16.2 0.0 0.29 11.0 0.0 2.9 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KDO18791.1 - 0.0073 16.4 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KDO18791.1 - 0.0085 16.2 0.0 0.95 9.6 0.0 3.7 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_25 PF13481.6 KDO18791.1 - 0.015 14.9 0.1 0.097 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO18791.1 - 0.031 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KDO18791.1 - 0.034 14.6 0.1 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 KDO18791.1 - 0.039 13.7 0.3 7.8 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KDO18791.1 - 0.045 13.6 0.0 2.6 7.9 0.0 3.1 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 KDO18791.1 - 0.068 12.3 0.0 0.95 8.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 KDO18791.1 - 0.071 12.5 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein Cytidylate_kin PF02224.18 KDO18791.1 - 0.079 12.7 0.2 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 KDO18791.1 - 0.083 12.8 0.0 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 KDO18791.1 - 0.1 12.5 0.0 6.3 6.6 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KDO18791.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KDO18791.1 - 0.13 12.2 0.1 50 3.7 0.0 3.4 3 0 0 3 3 3 0 RsgA GTPase AAA_19 PF13245.6 KDO18791.1 - 0.21 11.9 6.3 2.2 8.6 0.0 3.7 3 1 0 3 3 3 0 AAA domain Methyltr_RsmB-F PF01189.17 KDO18793.1 - 9.2e-20 71.1 0.1 2.1e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F SDA1 PF05285.12 KDO18793.1 - 0.013 15.0 18.6 0.016 14.6 18.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KDO18793.1 - 0.017 13.4 16.5 0.02 13.1 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KDO18793.1 - 0.071 12.7 17.0 0.14 11.7 17.0 1.5 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 KDO18793.1 - 0.18 10.5 5.6 0.19 10.5 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Menin PF05053.13 KDO18793.1 - 0.55 8.5 9.4 0.66 8.3 9.4 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.14 KDO18793.1 - 1.2 7.3 12.8 1.7 6.9 12.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KDO18793.1 - 3.8 5.5 7.5 4.1 5.4 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_2 PF12796.7 KDO18794.1 - 3.3e-54 181.4 17.1 8.6e-13 48.7 0.0 7.0 4 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18794.1 - 1.7e-47 159.2 12.7 9e-13 48.5 0.0 9.6 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18794.1 - 4e-40 131.2 6.6 4.8e-06 26.5 0.0 13.4 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 KDO18794.1 - 3.6e-38 129.1 16.4 2.2e-08 34.2 0.1 9.7 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO18794.1 - 1.9e-37 126.1 18.5 1.7e-07 31.4 0.0 12.2 13 0 0 13 13 13 8 Ankyrin repeat Pkinase PF00069.25 KDO18794.1 - 3.3e-26 92.2 0.0 7.5e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18794.1 - 4.7e-25 88.4 0.0 1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18794.1 - 0.092 12.0 0.0 3.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DZR PF12773.7 KDO18794.1 - 0.34 11.0 11.7 0.11 12.5 6.4 2.8 2 1 2 4 4 4 0 Double zinc ribbon HEAT PF02985.22 KDO18795.1 - 6.8e-05 22.8 0.0 0.00043 20.3 0.0 2.5 1 0 0 1 1 1 1 HEAT repeat CLASP_N PF12348.8 KDO18795.1 - 0.011 15.3 0.4 0.55 9.8 0.0 2.5 2 1 0 2 2 2 0 CLASP N terminal Glycos_transf_1 PF00534.20 KDO18796.1 - 0.001 18.6 0.1 0.0025 17.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO18796.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Herpes_capsid PF06112.11 KDO18797.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MA3 PF02847.17 KDO18800.1 - 0.0057 16.6 1.0 0.0075 16.2 1.0 1.3 1 0 0 1 1 1 1 MA3 domain SAM_KSR1 PF13543.6 KDO18800.1 - 0.069 13.3 6.5 0.13 12.4 6.5 1.4 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Exonuc_VII_L PF02601.15 KDO18800.1 - 0.069 12.7 6.5 0.08 12.5 6.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 KDO18800.1 - 0.091 11.3 3.0 0.092 11.3 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PEPcase_2 PF14010.6 KDO18800.1 - 0.23 9.9 2.3 0.26 9.8 2.3 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase FdhE PF04216.12 KDO18800.1 - 0.24 11.3 3.9 0.27 11.1 3.9 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation FliP PF00813.20 KDO18800.1 - 0.37 10.6 1.3 0.48 10.3 1.3 1.2 1 0 0 1 1 1 0 FliP family SLIDE PF09111.10 KDO18800.1 - 1 9.4 7.4 0.92 9.6 3.1 2.0 1 1 1 2 2 2 0 SLIDE DUF4061 PF13270.6 KDO18800.1 - 1.1 9.7 12.4 5.1 7.5 12.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) FapA PF03961.13 KDO18800.1 - 1.8 7.1 9.2 2 6.9 9.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A CDC37_N PF03234.14 KDO18800.1 - 2.1 9.3 8.8 2.9 8.8 8.8 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding UPF0242 PF06785.11 KDO18800.1 - 2.4 8.2 15.6 3.2 7.8 15.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Arc_C PF18162.1 KDO18803.1 - 0.043 13.7 0.0 0.16 11.8 0.0 1.8 1 1 1 2 2 2 0 Arc C-lobe YwiC PF14256.6 KDO18804.1 - 0.18 12.1 5.3 0.077 13.3 2.4 1.9 2 0 0 2 2 2 0 YwiC-like protein DUF4149 PF13664.6 KDO18804.1 - 3.6 8.0 8.5 61 4.0 8.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) PAP_assoc PF03828.19 KDO18807.1 - 6.6e-16 58.3 0.0 1.3e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KDO18807.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF2621 PF11084.8 KDO18807.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Acyl_transf_3 PF01757.22 KDO18808.1 - 4e-15 55.7 34.9 1.4e-14 54.0 30.8 2.8 1 1 1 2 2 2 1 Acyltransferase family UDPGP PF01704.18 KDO18809.1 - 8.3e-11 41.2 0.0 9.6e-11 40.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ricin_B_lectin PF00652.22 KDO18810.1 - 1.3e-31 109.5 15.5 1.5e-14 54.3 3.1 3.6 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO18810.1 - 2.6e-13 50.5 7.8 7.2e-05 23.5 0.7 3.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_17 PF00332.18 KDO18810.1 - 0.018 14.6 1.4 0.028 14.0 0.9 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 PQQ PF01011.21 KDO18810.1 - 0.055 13.4 0.1 14 5.8 0.0 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Ricin_B_lectin PF00652.22 KDO18811.1 - 4.9e-31 107.6 12.4 2.7e-15 56.8 2.3 3.4 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO18811.1 - 7.1e-14 52.3 8.6 3.9e-06 27.5 0.9 3.7 1 1 3 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO18811.1 - 0.00016 21.3 0.6 0.056 13.0 0.1 2.6 2 1 1 3 3 3 2 Cytolethal distending toxin A/C domain Glyco_hydro_17 PF00332.18 KDO18811.1 - 0.03 13.9 0.5 0.059 13.0 0.5 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Sds3 PF08598.11 KDO18812.1 - 4e-07 30.3 2.9 8.4e-07 29.2 2.9 1.4 1 0 0 1 1 1 1 Sds3-like Bromo_coat PF01318.18 KDO18812.1 - 0.028 14.5 0.1 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Bromovirus coat protein TRPM_tetra PF16519.5 KDO18812.1 - 0.051 13.7 0.8 0.99 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetramerisation domain of TRPM MCD_N PF17408.2 KDO18812.1 - 3.5 7.8 7.6 1 9.5 1.6 2.6 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain Peptidase_C1 PF00112.23 KDO18813.1 - 4.2e-79 265.7 4.0 5.6e-79 265.2 4.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.15 KDO18813.1 - 1.4e-13 51.4 0.1 8.2e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 ML domain Inhibitor_I29 PF08246.12 KDO18813.1 - 5.2e-11 42.8 1.7 5.2e-11 42.8 1.7 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KDO18813.1 - 8e-07 28.2 0.9 0.00024 20.0 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family SKN1 PF03935.15 KDO18814.1 - 9.2e-57 192.6 18.0 8.8e-39 133.3 11.9 5.0 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO18814.1 - 0.063 13.6 6.0 0.026 14.8 2.8 2.1 2 0 0 2 2 2 0 EB module Pico_P2A PF00947.19 KDO18814.1 - 0.073 13.1 1.1 1.6 8.8 0.2 2.5 1 1 1 2 2 2 0 Picornavirus core protein 2A DX PF01666.17 KDO18814.1 - 1 9.8 7.6 1.5 9.3 0.9 2.9 3 0 0 3 3 3 0 DX module Nodulin_late PF07127.11 KDO18814.1 - 1.1 9.6 3.9 0.69 10.3 1.2 2.0 2 0 0 2 2 2 0 Late nodulin protein VPS13_C PF16909.5 KDO18815.1 - 2.4e-22 79.5 1.6 6.1e-20 71.7 0.1 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal C2 PF00168.30 KDO18815.1 - 2.4e-20 72.8 0.0 9.3e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain SHR-BD PF06650.12 KDO18815.1 - 2.2e-13 50.2 0.0 6.1e-11 42.2 0.0 3.9 3 1 1 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_1 PF00036.32 KDO18816.1 - 1.3e-10 40.1 0.4 8.5e-07 28.1 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO18816.1 - 1.9e-09 37.8 1.2 4.3e-09 36.7 1.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO18816.1 - 1.7e-08 33.7 0.6 4.4e-05 23.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO18816.1 - 5.4e-06 25.7 0.4 3.9e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 EF hand VPS13 PF16908.5 KDO18816.1 - 0.00016 21.6 0.3 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal EF-hand_8 PF13833.6 KDO18816.1 - 0.002 17.9 0.2 0.0054 16.6 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair Chorein_N PF12624.7 KDO18816.1 - 0.0051 16.9 0.1 0.03 14.4 0.0 2.4 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 Pro-kuma_activ PF09286.11 KDO18817.1 - 2e-13 50.9 0.0 3.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KDO18817.1 - 3.9e-07 29.6 0.1 6.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Subtilase family LRR_6 PF13516.6 KDO18819.1 - 0.03 14.3 5.2 11 6.4 0.1 4.6 4 1 0 4 4 4 0 Leucine Rich repeat DUF4350 PF14258.6 KDO18819.1 - 0.083 13.3 0.3 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) LRR_4 PF12799.7 KDO18819.1 - 3.5 8.2 10.6 32 5.1 0.3 4.4 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) PH PF00169.29 KDO18820.1 - 0.00021 21.8 0.1 0.00026 21.5 0.1 1.2 1 0 0 1 1 1 1 PH domain Cytochrom_C PF00034.21 KDO18821.1 - 7.6e-13 49.4 0.4 1.2e-12 48.8 0.4 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KDO18821.1 - 1.3e-06 28.6 4.1 6e-06 26.5 4.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KDO18821.1 - 0.0046 16.7 0.6 0.0099 15.6 0.2 1.7 2 1 0 2 2 2 1 Cytochrome c-550 domain Brix PF04427.18 KDO18822.1 - 3.7e-20 72.9 1.1 4.2e-20 72.7 1.1 1.0 1 0 0 1 1 1 1 Brix domain EcoRII-C PF09019.11 KDO18822.1 - 0.017 15.2 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 EcoRII C terminal CN_hydrolase PF00795.22 KDO18823.1 - 5.3e-37 127.6 0.0 6.8e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_S15 PF00312.22 KDO18824.1 - 7.1e-34 115.9 1.7 9.6e-34 115.4 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Sec20 PF03908.13 KDO18824.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.5 1 1 0 1 1 1 0 Sec20 HR1 PF02185.16 KDO18824.1 - 0.4 10.8 4.6 0.17 12.0 1.7 1.8 2 0 0 2 2 2 0 Hr1 repeat MORN PF02493.20 KDO18825.1 - 5.2e-31 104.7 44.9 8.9e-07 28.5 0.8 7.1 7 0 0 7 7 7 6 MORN repeat EF-hand_7 PF13499.6 KDO18825.1 - 0.0017 18.8 0.0 0.0039 17.6 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO18825.1 - 0.071 13.1 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Ssu72 PF04722.13 KDO18826.1 - 3.3e-65 219.3 0.0 3.6e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein FlaC_arch PF05377.11 KDO18827.1 - 0.00023 21.5 2.3 0.0016 18.8 0.1 2.9 2 1 0 3 3 3 1 Flagella accessory protein C (FlaC) PBC PF03792.13 KDO18827.1 - 0.00098 18.9 6.6 0.0021 17.9 6.6 1.6 1 1 0 1 1 1 1 PBC domain GAS PF13851.6 KDO18827.1 - 0.0042 16.5 9.5 0.0058 16.0 9.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 KDO18827.1 - 0.0063 16.8 1.2 0.0063 16.8 1.2 3.0 3 1 0 3 3 3 1 Csm1 N-terminal domain BLOC1_2 PF10046.9 KDO18827.1 - 0.072 13.4 5.4 0.2 12.0 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KDO18827.1 - 0.11 12.5 12.7 0.99 9.5 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 KDO18827.1 - 0.24 11.5 7.2 1.9 8.6 0.3 2.7 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Baculo_PEP_C PF04513.12 KDO18827.1 - 0.55 10.3 6.9 0.83 9.7 0.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KDO18827.1 - 0.62 10.6 4.0 7 7.2 2.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prp19 PF08606.11 KDO18827.1 - 0.77 9.8 8.3 2.6 8.1 1.9 2.7 2 1 0 2 2 2 0 Prp19/Pso4-like Laminin_II PF06009.12 KDO18827.1 - 0.83 9.7 12.9 4 7.4 4.5 2.3 1 1 1 2 2 2 0 Laminin Domain II UPF0242 PF06785.11 KDO18827.1 - 0.86 9.7 9.0 0.35 11.0 1.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KDO18827.1 - 1.4 8.7 8.6 0.23 11.2 1.3 2.8 2 2 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 KDO18827.1 - 5.7 7.3 6.8 1 9.6 0.6 2.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain CTP_transf_1 PF01148.20 KDO18830.1 - 2.7e-37 129.0 13.7 1e-35 123.8 11.2 2.4 2 1 0 2 2 2 2 Cytidylyltransferase family AMPK1_CBM PF16561.5 KDO18831.1 - 2.8e-34 117.2 0.3 5e-34 116.4 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KDO18831.1 - 2.5e-25 88.5 2.0 2.5e-25 88.5 2.0 1.7 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Ost5 PF05251.12 KDO18832.1 - 4.7e-20 71.6 7.9 5.1e-20 71.5 7.9 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 FixS PF03597.15 KDO18832.1 - 8 6.3 12.7 1.7 8.4 4.7 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type GSHPx PF00255.19 KDO18833.1 - 1.3e-37 127.6 0.0 1.7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KDO18833.1 - 1.4e-06 28.3 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO18833.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin Pribosyltran PF00156.27 KDO18837.1 - 7.9e-21 74.2 0.1 1.3e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KDO18837.1 - 0.12 11.9 0.4 0.19 11.2 0.4 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase zf-RVT PF13966.6 KDO18843.1 - 0.0032 18.1 0.2 0.0032 18.1 0.2 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF2742 PF10888.8 KDO18843.1 - 3.3 8.0 6.4 1.4 9.2 0.2 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2742) PseudoU_synth_1 PF01416.20 KDO18844.1 - 2.5e-27 95.5 0.0 1.8e-24 86.3 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase GRP PF07172.11 KDO18845.1 - 0.0035 18.0 29.8 0.018 15.7 29.8 1.9 1 1 0 1 1 1 1 Glycine rich protein family Keratin_2_tail PF16210.5 KDO18845.1 - 1 9.6 29.3 1.4 9.2 29.3 1.1 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail Trypan_PARP PF05887.11 KDO18845.1 - 1.7 8.6 28.7 0.023 14.6 16.5 2.9 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) RCC1 PF00415.18 KDO18846.1 - 1e-22 80.5 0.3 3e-12 47.0 0.0 2.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO18846.1 - 1e-10 41.1 0.8 0.00027 20.7 0.5 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KDO18846.1 - 3.4e-07 30.0 16.4 1.8e-06 27.8 16.4 2.3 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KDO18846.1 - 0.029 14.3 10.8 0.067 13.1 10.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4213 PF13938.6 KDO18846.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation Zf_RING PF16744.5 KDO18846.1 - 1.4 9.0 7.7 2.6 8.2 7.7 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger DnaJ PF00226.31 KDO18847.1 - 6.9e-25 87.0 1.3 8.8e-25 86.6 1.3 1.1 1 0 0 1 1 1 1 DnaJ domain FAD_binding_8 PF08022.12 KDO18848.1 - 1.3e-19 70.3 0.5 2.5e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KDO18848.1 - 1e-13 51.5 13.4 2.1e-13 50.5 13.4 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO18848.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KDO18848.1 - 0.025 14.9 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF35_N PF12172.8 KDO18848.1 - 0.064 13.1 0.2 0.064 13.1 0.2 1.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 KDO18849.1 - 1.7e-48 165.3 0.0 2.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18849.1 - 3.5e-44 151.0 0.0 4.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO18849.1 - 1.4e-08 34.3 3.9 1e-06 28.4 0.3 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO18849.1 - 2.7e-08 34.0 1.2 1.8e-05 25.0 0.5 2.9 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO18849.1 - 2.5e-06 27.1 0.0 0.34 11.1 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KDO18849.1 - 0.00053 20.2 0.4 5.8 7.9 0.1 4.0 4 0 0 4 4 4 1 Leucine Rich Repeat SKG6 PF08693.10 KDO18849.1 - 0.0017 17.7 0.4 0.0032 16.8 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kinase-like PF14531.6 KDO18849.1 - 0.0018 17.7 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO18849.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_9 PF14580.6 KDO18849.1 - 0.022 14.2 0.1 0.3 10.6 0.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeat Pkinase PF00069.25 KDO18850.1 - 7.1e-42 143.6 0.0 9.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18850.1 - 3.9e-39 134.5 0.0 5.4e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO18850.1 - 3.3e-07 30.0 5.0 0.0013 18.4 2.8 3.3 1 1 1 3 3 3 2 Leucine rich repeat SKG6 PF08693.10 KDO18850.1 - 0.0054 16.1 2.6 0.011 15.2 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_4 PF12799.7 KDO18850.1 - 0.033 14.6 3.6 0.033 14.6 3.6 2.7 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) MHYT PF03707.16 KDO18850.1 - 0.034 14.3 1.5 0.14 12.3 1.5 2.1 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat LRR_6 PF13516.6 KDO18850.1 - 0.035 14.2 4.4 13 6.1 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Methyltransf_25 PF13649.6 KDO18851.1 - 6.4e-35 119.8 0.0 2e-17 63.7 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KDO18851.1 - 1e-33 115.8 0.0 3.8e-17 62.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KDO18851.1 - 2.3e-27 95.6 0.0 1.4e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KDO18851.1 - 1.5e-26 93.2 0.0 3e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18851.1 - 4.7e-22 78.6 0.0 2.2e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 KDO18851.1 - 6.6e-15 55.1 0.0 1.3e-13 50.9 0.0 2.1 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KDO18851.1 - 3.1e-13 49.6 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CheR PF01739.18 KDO18851.1 - 1.6e-11 44.1 0.0 0.00054 19.5 0.0 3.3 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.12 KDO18851.1 - 3.2e-11 43.2 0.0 2.1e-08 33.9 0.0 2.9 3 0 0 3 3 3 1 AdoMet dependent proline di-methyltransferase TPMT PF05724.11 KDO18851.1 - 5.2e-09 36.1 0.0 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 KDO18851.1 - 8.8e-09 34.7 0.0 8.3e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) NodS PF05401.11 KDO18851.1 - 1.8e-07 31.0 0.0 7.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 KDO18851.1 - 3.1e-07 30.1 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 KDO18851.1 - 2.4e-06 27.5 0.0 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KDO18851.1 - 9.1e-05 21.9 0.0 0.53 9.7 0.0 2.5 3 0 0 3 3 3 2 Tellurite resistance protein TehB RrnaAD PF00398.20 KDO18851.1 - 9.5e-05 21.6 0.0 0.00045 19.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KDO18851.1 - 0.0005 19.4 0.0 0.14 11.4 0.0 2.5 2 1 0 2 2 2 1 O-methyltransferase domain MetW PF07021.12 KDO18851.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 KDO18851.1 - 0.014 14.0 0.0 0.83 8.1 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 KDO18851.1 - 0.036 13.5 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KDO18851.1 - 0.042 13.8 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Bin3 PF06859.12 KDO18851.1 - 0.1 13.3 0.0 11 6.7 0.0 2.7 2 1 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 KDO18852.1 - 1.5e-20 73.7 0.2 2.4e-17 63.4 0.0 3.1 3 1 1 4 4 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 KDO18852.1 - 9.9e-20 71.0 0.0 3.2e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO18852.1 - 1.3e-19 70.6 0.1 4.9e-17 62.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO18852.1 - 3.7e-19 69.0 0.0 1.8e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18852.1 - 1.3e-14 54.7 0.0 2.8e-12 47.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KDO18852.1 - 3.5e-14 52.8 0.0 1.3e-13 50.9 0.0 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KDO18852.1 - 4.6e-08 32.7 0.1 1.1e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 KDO18852.1 - 8.1e-06 25.5 0.0 0.001 18.6 0.0 3.0 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 KDO18852.1 - 9.2e-06 24.8 0.0 3.5e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KDO18852.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 KDO18852.1 - 0.00055 19.7 0.0 0.0015 18.3 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KDO18852.1 - 0.00056 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KDO18852.1 - 0.002 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KDO18852.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KDO18852.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Pkinase PF00069.25 KDO18853.1 - 8.1e-50 169.6 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18853.1 - 1.2e-45 155.9 0.0 1.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO18853.1 - 7.6e-07 28.8 5.1 0.00032 20.4 0.3 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO18853.1 - 1.2e-06 28.7 1.7 5.3e-05 23.5 0.4 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 KDO18853.1 - 9.6e-05 21.8 0.3 0.00028 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like LRR_6 PF13516.6 KDO18853.1 - 0.0083 16.1 0.1 8.4 6.7 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeat LRR_9 PF14580.6 KDO18853.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Pkinase_fungal PF17667.1 KDO18853.1 - 0.077 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO18853.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RSN1_7TM PF02714.15 KDO18854.1 - 9.9e-28 97.2 12.8 2.6e-27 95.9 12.8 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KDO18854.1 - 3.4e-26 91.9 0.3 3.2e-25 88.7 0.0 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KDO18854.1 - 7.6e-22 78.4 1.1 1.8e-19 70.6 1.1 2.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 KDO18854.1 - 0.011 14.5 0.4 0.022 13.6 0.4 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF848 PF05852.11 KDO18854.1 - 0.09 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_TATA_bd PF12325.8 KDO18855.1 - 3.9 7.7 19.9 0.82 9.9 8.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RSN1_7TM PF02714.15 KDO18856.1 - 2.2e-41 142.0 20.2 1.1e-40 139.7 20.2 2.1 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KDO18856.1 - 3.3e-28 98.4 1.0 3.3e-28 98.4 1.0 3.4 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KDO18856.1 - 8.9e-23 81.4 1.9 6e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 KDO18856.1 - 0.15 10.8 5.7 0.065 12.1 3.0 1.6 1 1 0 1 1 1 0 Calcium-activated chloride channel RSN1_7TM PF02714.15 KDO18857.1 - 1.9e-49 168.5 17.2 3.6e-49 167.5 17.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KDO18857.1 - 1.8e-34 118.7 0.8 1.8e-34 118.7 0.8 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KDO18857.1 - 6.8e-24 85.0 0.4 3.6e-22 79.4 0.4 2.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4684 PF15736.5 KDO18857.1 - 0.028 13.1 0.9 0.042 12.5 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) SET_assoc PF11767.8 KDO18857.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated LAGLIDADG_WhiA PF14527.6 KDO18858.1 - 0.0098 15.9 0.2 7 6.8 0.0 3.4 4 0 0 4 4 3 1 WhiA LAGLIDADG-like domain Zw10 PF06248.13 KDO18858.1 - 0.013 14.2 1.3 0.017 13.7 1.3 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DASH_Dad2 PF08654.10 KDO18858.1 - 0.022 15.2 6.6 0.061 13.8 6.6 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 LCD1 PF09798.9 KDO18858.1 - 0.053 12.0 10.6 0.076 11.5 10.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TBCC_N PF16752.5 KDO18858.1 - 0.054 14.0 8.9 0.13 12.7 8.9 1.6 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain UPF0242 PF06785.11 KDO18858.1 - 0.059 13.5 12.0 0.11 12.5 12.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Rho_Binding PF08912.11 KDO18858.1 - 0.18 12.6 7.1 1.1 10.1 1.3 2.6 2 0 0 2 2 2 0 Rho Binding BORCS8 PF10167.9 KDO18858.1 - 0.21 11.5 5.0 5.9 6.9 2.1 3.0 2 2 1 3 3 3 0 BLOC-1-related complex sub-unit 8 DUF4407 PF14362.6 KDO18858.1 - 0.4 10.0 7.4 0.66 9.3 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 KDO18858.1 - 0.41 11.0 8.5 7 7.1 2.2 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Myb_DNA-bind_6 PF13921.6 KDO18858.1 - 1.9 8.8 5.5 23 5.4 1.1 2.7 1 1 1 2 2 2 0 Myb-like DNA-binding domain Fungal_TACC PF12709.7 KDO18858.1 - 2.4 8.7 8.7 12 6.4 3.5 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 KDO18858.1 - 3.2 8.3 15.8 3.6 8.1 13.6 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Prefoldin PF02996.17 KDO18858.1 - 4 7.4 8.6 2 8.3 3.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit Glu-tRNAGln PF02686.15 KDO18858.1 - 4.9 7.5 7.3 4.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit PRP1_N PF06424.12 KDO18858.1 - 7 7.0 15.2 83 3.6 14.0 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal DivIC PF04977.15 KDO18858.1 - 7.9 6.3 11.9 9 6.1 4.9 2.4 2 0 0 2 2 2 0 Septum formation initiator Elicitin PF00964.17 KDO18859.1 - 6.5e-07 29.4 0.8 1e-06 28.7 0.8 1.4 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO18860.1 - 4.6e-07 29.9 1.0 4.6e-07 29.9 1.0 1.7 2 0 0 2 2 2 1 Elicitin Glyco_transf_22 PF03901.17 KDO18862.1 - 5e-23 82.0 2.9 5.8e-23 81.8 2.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MitoNEET_N PF10660.9 KDO18864.1 - 2.6e-14 53.0 0.5 3.5e-14 52.5 0.5 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 KDO18864.1 - 9.2e-11 41.8 1.0 1.8e-10 40.9 1.0 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type PH PF00169.29 KDO18865.1 - 5.6e-09 36.5 0.0 9.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 KDO18865.1 - 0.0021 17.9 0.4 0.011 15.6 0.1 2.0 1 1 0 2 2 2 1 Pleckstrin homology domain Neuropep_like PF15161.6 KDO18865.1 - 0.026 14.2 0.1 0.082 12.6 0.1 1.9 1 0 0 1 1 1 0 Neuropeptide-like SPG48 PF14764.6 KDO18866.1 - 0.094 13.2 3.0 0.17 12.4 0.6 2.9 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking HSP70 PF00012.20 KDO18867.1 - 3.3e-137 458.2 12.6 4.6e-137 457.7 12.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO18867.1 - 1.3e-08 34.1 6.1 1.4e-07 30.7 2.8 2.5 2 1 0 2 2 2 2 MreB/Mbl protein cPLA2_C2 PF18695.1 KDO18867.1 - 0.13 12.3 0.2 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain DUF2451 PF10474.9 KDO18868.1 - 3.2e-46 158.0 0.5 6.7e-46 157.0 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KDO18868.1 - 6.6e-27 94.5 2.3 4.4e-26 91.8 2.3 2.2 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex EAV_GS PF01309.18 KDO18868.1 - 0.045 13.4 0.1 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein DUF1836 PF08876.11 KDO18868.1 - 0.077 13.0 0.1 0.3 11.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Glutaredoxin PF00462.24 KDO18869.1 - 3.6e-51 171.2 0.0 3.3e-16 59.2 0.0 3.5 3 0 0 3 3 3 3 Glutaredoxin SH3BGR PF04908.15 KDO18869.1 - 0.0013 18.9 0.0 1.5 9.0 0.0 3.5 3 1 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Thioredoxin PF00085.20 KDO18869.1 - 0.0015 18.5 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin 6PF2K PF01591.18 KDO18869.1 - 0.0025 17.2 0.0 1.4 8.2 0.0 3.0 3 0 0 3 3 3 1 6-phosphofructo-2-kinase GST_N_3 PF13417.6 KDO18869.1 - 0.009 16.4 0.0 1.7 9.1 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain ZinT PF09223.11 KDO18869.1 - 0.016 15.1 0.1 3.3 7.6 0.0 2.5 3 0 0 3 3 3 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment RdRP PF05183.12 KDO18869.1 - 0.064 11.9 0.0 28 3.2 0.0 2.9 1 1 2 3 3 3 0 RNA dependent RNA polymerase CxC1 PF18802.1 KDO18869.1 - 0.092 12.9 0.0 20 5.4 0.0 3.0 3 0 0 3 3 3 0 CxC1 like cysteine cluster associated with KDZ transposases Ricin_B_lectin PF00652.22 KDO18870.1 - 1.3e-06 28.7 0.5 1e-05 25.8 0.4 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO18870.1 - 0.0022 18.7 0.1 0.11 13.2 0.0 2.5 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like EAP30 PF04157.16 KDO18871.1 - 5.5e-41 140.4 1.9 7e-41 140.0 1.9 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KDO18871.1 - 1.6e-15 57.0 0.1 1e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KDO18871.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 GRAM domain HTH_24 PF13412.6 KDO18871.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran PF00005.27 KDO18876.1 - 1.7e-14 54.5 0.0 2.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO18876.1 - 5.5e-12 45.9 2.8 7e-12 45.6 2.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF87 PF01935.17 KDO18876.1 - 0.0059 16.7 0.3 0.018 15.1 0.2 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 KDO18876.1 - 0.0063 16.6 0.3 0.022 14.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO18876.1 - 0.028 14.1 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO18876.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO18876.1 - 0.16 12.2 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KDO18876.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ldt_C PF17969.1 KDO18878.1 - 0.041 14.6 0.0 0.12 13.1 0.0 1.7 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain bZIP_1 PF00170.21 KDO18878.1 - 0.42 10.7 6.9 0.62 10.2 6.9 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KDO18878.1 - 0.58 10.3 5.6 1.2 9.2 5.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CHD5 PF04420.14 KDO18879.1 - 2.2e-10 40.6 0.0 2.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 CHD5-like protein DEAD PF00270.29 KDO18880.1 - 7.9e-30 103.9 0.0 4.2e-28 98.3 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO18880.1 - 1.2e-28 99.6 0.0 4.2e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 KDO18880.1 - 0.0031 17.5 1.6 0.0031 17.5 1.6 2.0 2 0 0 2 2 2 1 Zinc knuckle SecA_DEAD PF07517.14 KDO18880.1 - 0.021 14.1 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Carn_acyltransf PF00755.20 KDO18882.1 - 1.6e-151 505.9 0.0 1.8e-151 505.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PH PF00169.29 KDO18883.1 - 6.6e-14 52.3 0.1 8.9e-07 29.4 0.0 3.2 2 1 1 3 3 3 2 PH domain PH_11 PF15413.6 KDO18883.1 - 3.3e-07 30.7 4.2 0.00081 19.8 1.5 3.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KDO18883.1 - 0.0012 18.6 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 KDO18883.1 - 0.0028 17.5 0.0 0.04 13.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KDO18883.1 - 0.073 13.4 0.0 8.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 KDO18883.1 - 0.091 13.1 0.5 13 6.2 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_5 PF15405.6 KDO18883.1 - 0.11 12.6 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain CRCB PF02537.15 KDO18884.1 - 4.2e-30 103.9 28.3 1.4e-17 63.8 6.8 2.6 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Methyltransf_5 PF01795.19 KDO18885.1 - 2.3e-88 296.7 0.0 2.6e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KDO18885.1 - 0.00012 22.7 0.0 0.00035 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO18885.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18885.1 - 0.013 16.3 0.0 0.069 13.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DIM1 PF02966.16 KDO18886.1 - 9.5e-66 219.6 0.1 1.1e-65 219.4 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KDO18886.1 - 0.0088 16.0 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KDO18886.1 - 0.053 13.8 0.1 0.08 13.3 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like LSM PF01423.22 KDO18887.1 - 8.7e-21 73.4 0.0 1e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KDO18887.1 - 0.055 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain UDPG_MGDP_dh_N PF03721.14 KDO18888.1 - 5.2e-57 192.5 0.0 1.6e-56 190.9 0.0 1.8 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KDO18888.1 - 3.2e-32 110.6 0.0 6.8e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KDO18888.1 - 1.9e-30 105.4 0.1 1.4e-28 99.3 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Apyrase PF06079.11 KDO18889.1 - 2.1e-88 296.3 0.0 2.4e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Apyrase Ribosomal_60s PF00428.19 KDO18890.1 - 6.3e-21 74.8 10.2 7.5e-21 74.5 10.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Adaptin_N PF01602.20 KDO18891.1 - 4.6e-106 355.5 6.2 6.5e-106 355.0 6.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KDO18891.1 - 5.3e-18 65.6 2.4 2.2e-13 50.6 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KDO18891.1 - 6.6e-05 23.2 0.0 1.3 9.4 0.0 3.8 3 1 0 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 KDO18891.1 - 0.00062 19.9 0.8 0.48 10.6 0.2 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KDO18891.1 - 0.028 13.6 0.9 0.21 10.8 0.1 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DM4_12 PF07841.13 KDO18891.1 - 0.039 14.6 0.1 0.56 10.9 0.0 2.9 3 0 0 3 3 3 0 DM4/DM12 family HEAT PF02985.22 KDO18891.1 - 0.063 13.6 0.1 58 4.3 0.0 4.4 4 1 0 4 4 4 0 HEAT repeat MMS19_C PF12460.8 KDO18891.1 - 0.3 10.2 4.3 0.22 10.6 1.0 2.4 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal DUF2151 PF10221.9 KDO18891.1 - 1.9 7.0 9.8 3.8 6.0 9.8 1.5 1 0 0 1 1 1 0 Cell cycle and development regulator Snf7 PF03357.21 KDO18892.1 - 2.2e-14 53.5 8.4 2.7e-14 53.1 8.4 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KDO18892.1 - 0.0067 16.4 1.3 0.0087 16.0 1.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cep57_MT_bd PF06657.13 KDO18892.1 - 0.13 12.8 1.4 0.97 9.9 0.1 2.7 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Cytochrom_B562 PF07361.11 KDO18892.1 - 0.33 11.6 10.7 0.073 13.7 2.2 2.9 2 1 0 2 2 2 0 Cytochrome b562 MA3 PF02847.17 KDO18893.1 - 0.13 12.2 4.3 0.16 12.0 3.5 1.6 1 1 0 1 1 1 0 MA3 domain DUF4407 PF14362.6 KDO18893.1 - 1.4 8.2 16.0 2 7.7 15.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FH2 PF02181.23 KDO18893.1 - 1.7 7.7 18.8 0.3 10.2 2.7 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain FUSC PF04632.12 KDO18893.1 - 3.7 6.0 12.6 0.61 8.6 3.6 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 KDO18893.1 - 4.5 7.3 33.7 2.7 8.0 2.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KDO18893.1 - 4.9 7.2 26.5 3.3 7.8 15.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KDO18893.1 - 6.2 6.3 20.1 12 5.3 20.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit KLRAQ PF10205.9 KDO18893.1 - 7.7 6.8 21.3 0.051 13.8 5.3 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein NPV_P10 PF05531.12 KDO18893.1 - 8.2 7.0 9.5 22 5.6 4.0 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Erp_C PF06780.11 KDO18893.1 - 9 6.3 10.6 12 5.9 5.9 2.3 1 1 1 2 2 2 0 Erp protein C-terminus TMPIT PF07851.13 KDO18893.1 - 9.1 5.4 14.0 3.8 6.7 11.4 1.6 1 1 0 1 1 1 0 TMPIT-like protein SKA1 PF07160.12 KDO18893.1 - 9.8 5.9 19.9 1.4 8.8 3.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 KDO18896.1 - 9.7e-06 25.7 4.3 0.00014 22.0 5.3 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF29 PF01724.16 KDO18896.1 - 0.011 16.0 1.6 0.019 15.2 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 HAUS-augmin3 PF14932.6 KDO18896.1 - 0.049 13.2 4.5 0.069 12.7 4.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2046 PF09755.9 KDO18896.1 - 0.058 12.6 6.0 0.084 12.1 6.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Allexi_40kDa PF05549.11 KDO18896.1 - 0.071 12.6 3.0 0.12 11.9 3.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1690 PF07956.11 KDO18896.1 - 0.18 12.2 4.1 0.31 11.5 4.1 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) PRKG1_interact PF15898.5 KDO18896.1 - 0.29 12.0 5.8 0.51 11.3 5.8 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DivIVA PF05103.13 KDO18896.1 - 1.2 9.3 5.3 2 8.5 5.3 1.3 1 0 0 1 1 1 0 DivIVA protein Prefoldin PF02996.17 KDO18896.1 - 4.5 7.2 5.3 2.6 8.0 0.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit GspL_C PF12693.7 KDO18897.1 - 0.028 14.3 0.3 0.05 13.4 0.3 1.4 1 0 0 1 1 1 0 GspL periplasmic domain ADP_PFK_GK PF04587.15 KDO18898.1 - 1e-93 314.3 0.0 1.2e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF1148 PF06618.11 KDO18898.1 - 0.011 15.9 0.1 0.03 14.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Glycos_transf_2 PF00535.26 KDO18899.1 - 1.8e-28 99.5 0.0 2.7e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KDO18899.1 - 1.7e-10 41.2 0.0 2.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KDO18899.1 - 0.0072 15.8 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glu_syn_central PF04898.14 KDO18899.1 - 0.094 12.2 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain RcpB PF16971.5 KDO18899.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit F-box-like PF12937.7 KDO18900.1 - 0.0015 18.4 0.1 0.0033 17.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO18900.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain Vps5 PF09325.10 KDO18901.1 - 2.6e-35 122.1 1.5 3.3e-35 121.7 1.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KDO18901.1 - 7.1e-26 90.4 0.3 2.3e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KDO18901.1 - 0.00018 21.1 2.7 0.0026 17.2 2.7 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.13 KDO18901.1 - 0.0011 18.6 2.4 0.0017 18.0 2.4 1.2 1 0 0 1 1 1 1 Arfaptin-like domain GrpE PF01025.19 KDO18901.1 - 0.03 14.0 3.3 0.023 14.3 1.8 1.5 2 0 0 2 2 2 0 GrpE FAM92 PF06730.11 KDO18901.1 - 0.076 12.4 3.1 0.17 11.3 2.5 1.8 1 1 1 2 2 2 0 FAM92 protein MOZ_SAS PF01853.18 KDO18901.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Myb_DNA-binding PF00249.31 KDO18903.1 - 3.4e-20 72.0 5.3 1.8e-09 37.6 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO18903.1 - 5e-16 58.7 0.0 2.5e-08 34.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO18903.1 - 0.00017 21.9 4.2 0.0026 18.1 0.3 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain PXPV PF12778.7 KDO18903.1 - 0.51 10.3 9.7 2.3 8.2 9.7 2.1 1 0 0 1 1 1 0 PXPV repeat (3 copies) Glyco_hydro_63N PF16923.5 KDO18904.1 - 2.7e-29 102.9 0.1 3e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain WD40 PF00400.32 KDO18905.1 - 3.7e-05 24.4 8.4 0.00021 22.0 0.2 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat RNase_P_Rpp14 PF01900.19 KDO18906.1 - 2.6e-07 30.8 0.1 3.3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Pkinase_Tyr PF07714.17 KDO18907.1 - 2.9e-27 95.6 0.0 3.8e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO18907.1 - 1.8e-18 66.9 0.0 2.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MGC-24 PF05283.11 KDO18907.1 - 0.00022 21.7 0.2 0.00022 21.7 0.2 3.3 3 0 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Cytomega_TRL10 PF06084.11 KDO18907.1 - 0.0063 16.5 0.0 0.037 14.0 0.0 2.3 2 0 0 2 2 2 1 Cytomegalovirus TRL10 protein Syndecan PF01034.20 KDO18907.1 - 0.012 15.5 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Pox_A14 PF05767.12 KDO18907.1 - 0.016 15.3 0.0 0.11 12.7 0.0 2.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PTP_tm PF18861.1 KDO18907.1 - 0.051 13.6 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4366 PF14283.6 KDO18907.1 - 0.092 12.8 0.4 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Phage_HK97_TLTM PF06120.11 KDO18907.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein RIFIN PF02009.16 KDO18907.1 - 0.25 11.2 0.0 0.43 10.4 0.0 1.3 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 KDO18907.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 TMEM154 protein family Ribosomal_L27e PF01777.18 KDO18908.1 - 1.7e-24 86.0 6.0 2.3e-24 85.6 6.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KDO18908.1 - 0.00062 19.6 1.8 0.00062 19.6 1.8 2.3 3 0 0 3 3 3 1 KOW motif zf-C2H2_jaz PF12171.8 KDO18909.1 - 2.8e-06 27.5 5.6 0.00017 21.8 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KDO18909.1 - 1.6e-05 25.3 4.2 0.016 16.0 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KDO18909.1 - 4.7e-05 23.6 3.2 0.042 14.3 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KDO18909.1 - 0.0057 16.9 3.1 0.12 12.6 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KDO18909.1 - 0.017 15.5 3.5 1.1 9.7 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KDO18909.1 - 0.12 12.3 9.2 2 8.4 3.1 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF629 PF04780.12 KDO18909.1 - 0.15 10.6 0.8 0.21 10.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-BED PF02892.15 KDO18909.1 - 0.2 11.7 7.2 2.4 8.3 2.0 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KDO18909.1 - 0.23 11.8 3.4 11 6.4 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KDO18909.1 - 0.27 11.3 3.1 6.4 6.9 0.0 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.13 KDO18909.1 - 1.6 8.8 5.7 13 5.9 1.8 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Mlo PF03094.15 KDO18910.1 - 1e-05 24.2 5.1 0.014 13.8 0.3 2.4 2 0 0 2 2 2 2 Mlo family Spc110_C PF18520.1 KDO18910.1 - 0.076 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain PACT_coil_coil PF10495.9 KDO18910.1 - 0.098 13.2 0.2 0.22 12.1 0.2 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Malic_M PF03949.15 KDO18911.1 - 2.1e-94 315.6 0.5 2.7e-94 315.2 0.5 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KDO18911.1 - 3.2e-74 248.7 0.0 5.6e-74 247.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pyr_redox_2 PF07992.14 KDO18911.1 - 0.082 12.1 0.2 0.17 11.1 0.1 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF525 PF04379.14 KDO18912.1 - 9.5e-20 70.6 0.0 1.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 ApaG domain Complex1_LYR PF05347.15 KDO18912.1 - 0.00023 21.1 0.1 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO18912.1 - 0.011 16.5 0.0 0.018 15.8 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like PI3_PI4_kinase PF00454.27 KDO18917.1 - 2.3e-21 76.8 0.1 7.6e-17 62.0 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase WW PF00397.26 KDO18918.1 - 1.3e-05 25.1 0.7 2.9e-05 24.1 0.7 1.6 1 0 0 1 1 1 1 WW domain CENP-B_dimeris PF09026.10 KDO18918.1 - 0.26 11.7 14.9 0.36 11.2 14.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO18918.1 - 0.83 8.9 4.8 0.88 8.8 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KDO18918.1 - 7.5 6.2 11.4 9.3 5.9 11.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.16 KDO18921.1 - 3.4e-12 46.0 34.4 4.7e-12 45.5 34.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RPAP1_C PF08620.10 KDO18923.1 - 5.3e-22 77.7 0.0 1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KDO18923.1 - 3.7e-11 42.6 0.4 8.3e-11 41.5 0.4 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal zf-met2 PF12907.7 KDO18924.1 - 7e-15 54.9 3.3 1.2e-14 54.2 3.3 1.4 1 0 0 1 1 1 1 Zinc-binding zf-BED PF02892.15 KDO18924.1 - 0.012 15.6 0.4 0.019 15.0 0.4 1.3 1 0 0 1 1 1 0 BED zinc finger 4F5 PF04419.14 KDO18924.1 - 1.3 9.9 14.2 2.9 8.8 14.2 1.7 1 1 0 1 1 1 0 4F5 protein family MFS_1 PF07690.16 KDO18925.1 - 4.3e-08 32.5 32.0 2.9e-05 23.2 9.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KDO18926.1 - 6.3e-47 158.1 24.5 3.7e-14 53.1 0.6 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18926.1 - 4.1e-27 94.2 4.7 2.5e-08 34.3 0.0 6.6 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18926.1 - 2.2e-25 85.9 9.7 0.00017 21.7 0.1 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KDO18926.1 - 1.4e-21 75.9 17.6 0.0019 18.6 0.4 8.0 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KDO18926.1 - 1.7e-19 69.6 14.2 1e-06 28.9 0.4 6.5 4 3 4 8 8 8 4 Ankyrin repeats (many copies) RecR PF02132.15 KDO18926.1 - 0.92 9.1 2.9 2.9 7.5 0.1 2.7 3 0 0 3 3 3 0 RecR protein MFS_1 PF07690.16 KDO18927.1 - 8.1e-11 41.4 36.3 4e-09 35.9 24.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily RPN7 PF10602.9 KDO18928.1 - 2.1e-51 174.1 2.5 4.3e-51 173.1 1.7 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KDO18928.1 - 2.6e-14 53.6 0.0 7.1e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain ComR_TPR PF18710.1 KDO18928.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.9 1 1 0 1 1 1 1 ComR tetratricopeptide Ank_2 PF12796.7 KDO18930.1 - 3.7e-42 142.8 2.4 1.6e-10 41.4 0.2 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18930.1 - 4.4e-36 122.8 1.9 2.7e-08 34.2 0.0 7.0 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18930.1 - 1.4e-26 89.6 7.8 0.012 16.1 0.0 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 KDO18930.1 - 1.7e-23 82.0 17.6 0.0017 18.7 0.1 9.7 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KDO18930.1 - 7.1e-22 77.2 14.1 0.00037 20.7 0.0 7.6 1 1 8 9 9 9 7 Ankyrin repeats (many copies) 2-oxogl_dehyd_N PF16078.5 KDO18931.1 - 1.9e-20 72.1 0.5 2.6e-20 71.7 0.5 1.2 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Ntox17 PF15524.6 KDO18931.1 - 0.0028 17.9 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Novel toxin 17 EF-hand_6 PF13405.6 KDO18932.1 - 1.8e-11 43.0 9.7 0.029 14.3 0.5 7.3 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 KDO18932.1 - 2.8e-10 40.5 2.1 0.42 11.1 0.0 6.4 6 1 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 KDO18932.1 - 1.6e-08 33.5 5.2 0.029 13.9 0.1 5.9 6 0 0 6 6 6 3 EF hand DUF5580 PF17743.1 KDO18932.1 - 2.3e-05 23.2 0.0 0.031 12.8 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5580) EF-hand_8 PF13833.6 KDO18932.1 - 0.0037 17.1 0.0 2.8 7.8 0.0 4.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO18932.1 - 0.042 13.4 1.2 0.11 12.0 0.3 2.3 2 0 0 2 2 2 0 EF hand RST PF12174.8 KDO18932.1 - 0.59 10.1 4.1 78 3.3 0.0 4.2 5 0 0 5 5 5 0 RCD1-SRO-TAF4 (RST) plant domain zf-TAZ PF02135.16 KDO18933.1 - 8.4e-05 23.0 2.4 0.00012 22.4 2.4 1.2 1 0 0 1 1 1 1 TAZ zinc finger TTL PF03133.15 KDO18934.1 - 1.9e-100 335.8 0.2 2.6e-100 335.3 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO18934.1 - 7.7e-08 31.9 0.1 5.1e-05 22.7 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO18934.1 - 4.5e-05 22.8 0.0 0.0028 16.9 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Inhibitor_I66 PF16850.5 KDO18934.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I66 RimK PF08443.11 KDO18934.1 - 0.073 12.7 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Myb_DNA-binding PF00249.31 KDO18935.1 - 3.6e-27 94.3 0.4 1.4e-12 47.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO18935.1 - 1.4e-20 73.3 0.3 4.8e-13 49.2 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO18935.1 - 2.2e-07 30.7 0.0 0.00016 21.5 0.2 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 KDO18935.1 - 0.11 12.5 0.0 35 4.5 0.0 2.9 3 0 0 3 3 3 0 SLIDE GIT_CC PF16559.5 KDO18935.1 - 0.15 11.9 2.2 0.34 10.8 2.2 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FYVE PF01363.21 KDO18936.1 - 0.00019 21.5 15.1 0.00048 20.2 15.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO18936.1 - 0.055 13.7 12.5 0.17 12.1 12.5 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 KDO18936.1 - 0.072 13.4 9.3 0.22 11.9 9.3 1.8 1 0 0 1 1 1 0 C1 domain Laminin_EGF PF00053.24 KDO18936.1 - 0.57 10.4 6.7 2.3 8.4 2.3 2.7 1 1 1 2 2 2 0 Laminin EGF domain zf-B_box PF00643.24 KDO18936.1 - 2.8 8.2 12.5 0.21 11.8 6.4 2.2 2 1 0 2 2 2 0 B-box zinc finger Harakiri PF15196.6 KDO18937.1 - 0.036 14.5 3.7 0.043 14.3 2.5 1.7 1 1 0 1 1 1 0 Activator of apoptosis harakiri YidD PF01809.18 KDO18940.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor AMP-binding PF00501.28 KDO18941.1 - 8e-86 288.3 0.1 9.9e-86 287.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thump_like PF18096.1 KDO18941.1 - 0.017 15.1 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 0 THUMP domain-like AMP-binding PF00501.28 KDO18942.1 - 8.1e-60 202.6 0.1 1.2e-59 202.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 KDO18942.1 - 0.00024 21.1 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas2CT1978) Acyl-CoA_dh_N PF02771.16 KDO18943.1 - 6.1e-30 104.2 0.0 7.7e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 KDO18943.1 - 0.0075 16.8 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KDO18943.1 - 0.023 14.9 0.3 0.046 13.9 0.1 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KDO18944.1 - 5.6e-35 120.8 0.8 6.2e-35 120.6 0.8 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KDO18944.1 - 1.8e-15 57.4 0.0 2.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ALP_N PF17989.1 KDO18944.1 - 0.039 14.1 0.0 8 6.6 0.0 2.1 1 1 1 2 2 2 0 Actin like proteins N terminal domain NAD_synthase PF02540.17 KDO18945.1 - 2e-07 30.4 0.0 7.8e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 KDO18945.1 - 2.4e-06 26.6 0.0 0.00076 18.4 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 KDO18945.1 - 2.9e-05 23.9 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 KDO18945.1 - 4.5e-05 23.0 0.0 0.077 12.5 0.0 2.5 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 KDO18945.1 - 0.019 14.7 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.19 KDO18945.1 - 0.044 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Peptidase_A8 PF01252.18 KDO18947.1 - 0.0033 17.7 3.2 0.004 17.4 3.2 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II PhoR PF11808.8 KDO18947.1 - 1.3 9.4 4.3 0.83 10.1 2.6 1.5 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR DUF202 PF02656.15 KDO18947.1 - 2.2 8.8 11.5 0.35 11.4 6.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) N2227 PF07942.12 KDO18948.1 - 3.5e-79 265.8 0.0 4.3e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KDO18948.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO18948.1 - 0.001 19.8 0.0 0.0023 18.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO18948.1 - 0.017 15.8 0.0 0.15 12.7 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 KDO18949.1 - 1.2e-08 34.7 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18949.1 - 8.6e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 KDO18950.1 - 0.00064 19.6 0.3 1.8 8.8 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KDO18950.1 - 0.0018 18.6 2.8 0.032 14.6 0.7 3.3 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO18950.1 - 0.0018 18.5 2.6 0.74 10.6 0.2 4.3 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 KDO18950.1 - 0.11 12.3 5.2 0.41 10.4 1.9 3.1 3 1 0 3 3 3 0 Leucine rich repeat TPR_12 PF13424.6 KDO18951.1 - 1.9e-12 47.3 10.3 0.0052 17.0 1.5 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO18951.1 - 3.2e-10 39.6 11.9 0.00012 21.8 0.6 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO18951.1 - 0.015 15.3 3.9 2.5 8.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO18951.1 - 0.087 13.0 4.0 24 5.4 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CAP PF00188.26 KDO18952.1 - 2.8e-08 34.6 0.7 6.3e-08 33.5 0.7 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DPBB_1 PF03330.18 KDO18952.1 - 0.038 14.3 0.3 0.12 12.7 0.3 1.8 1 0 0 1 1 1 0 Lytic transglycolase MHC_II_beta PF00969.19 KDO18952.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain CAP PF00188.26 KDO18955.1 - 2e-09 38.4 1.1 3.3e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Ank_2 PF12796.7 KDO18956.1 - 2.3e-23 82.5 22.9 9.8e-08 32.5 0.3 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18956.1 - 7.7e-23 80.6 17.8 1.1e-06 29.0 0.6 6.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18956.1 - 1.7e-20 72.8 19.2 0.0071 16.6 0.3 8.9 1 1 8 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO18956.1 - 1.4e-10 40.5 13.6 0.4 11.4 0.2 9.3 7 2 3 10 10 10 2 Ankyrin repeat Ank PF00023.30 KDO18956.1 - 0.00012 22.4 14.6 17 6.1 0.4 8.4 3 2 3 6 6 6 1 Ankyrin repeat DUF5049 PF16468.5 KDO18956.1 - 0.0024 17.7 2.3 24 4.9 0.0 6.3 5 2 3 8 8 8 0 Domain of unknown function (DUF5049) DUF1707 PF08044.11 KDO18956.1 - 0.025 14.6 10.2 9.4 6.4 0.1 5.8 4 2 1 5 5 5 0 Domain of unknown function (DUF1707) Vps23_core PF09454.10 KDO18956.1 - 0.062 13.3 0.1 3.9 7.5 0.0 3.6 5 0 0 5 5 5 0 Vps23 core domain Pkinase PF00069.25 KDO18958.1 - 7.3e-32 110.8 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO18958.1 - 1.3e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO18958.1 - 0.098 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Aa_trans PF01490.18 KDO18960.1 - 1e-36 126.6 22.7 1.4e-36 126.2 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_10 PF13374.6 KDO18961.1 - 1.2e-12 47.3 3.2 3.7e-05 23.5 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO18961.1 - 1.3e-12 47.8 10.4 0.00021 21.5 0.2 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO18961.1 - 5.8e-08 32.2 0.3 0.0017 18.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO18961.1 - 1.4e-07 31.1 0.1 0.065 13.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO18961.1 - 4.7e-07 29.5 0.2 0.11 12.7 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO18961.1 - 2.6e-05 23.9 2.8 0.11 12.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO18961.1 - 0.00031 21.3 7.9 1.2 10.1 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO18961.1 - 0.036 14.7 5.7 2.9 8.8 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO18961.1 - 0.85 10.3 4.7 72 4.1 0.5 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO18962.1 - 1.4e-08 34.9 9.0 0.00043 20.5 1.7 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO18962.1 - 2.6e-08 33.5 7.3 0.021 14.7 0.1 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO18962.1 - 0.79 10.0 3.9 7.3 7.0 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.19 KDO18963.1 - 1.4e-37 128.9 0.0 1.5e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ABC_membrane PF00664.23 KDO18964.1 - 4.2e-24 85.6 7.1 5.3e-24 85.3 7.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Tcp11 PF05794.13 KDO18964.1 - 0.0084 15.2 0.3 0.011 14.9 0.3 1.1 1 0 0 1 1 1 1 T-complex protein 11 WSS_VP PF12175.8 KDO18964.1 - 0.21 11.0 0.3 0.43 10.0 0.1 1.6 1 1 1 2 2 2 0 White spot syndrome virus structural envelope protein VP SRC-1 PF08832.10 KDO18965.1 - 0.023 15.7 0.8 0.14 13.3 0.1 2.1 1 1 2 3 3 3 0 Steroid receptor coactivator ATP_synt_H PF05493.13 KDO18966.1 - 4.8e-14 52.6 7.4 6.4e-14 52.2 7.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4064 PF13273.6 KDO18966.1 - 0.0033 17.7 1.0 0.004 17.4 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Macro PF01661.21 KDO18967.1 - 3.2e-26 91.7 0.1 5.4e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO_2 PF13716.6 KDO18967.1 - 5.7e-24 84.8 0.1 1.1e-23 84.0 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KDO18967.1 - 0.0019 18.0 0.2 0.011 15.4 0.2 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain WD40 PF00400.32 KDO18968.1 - 6.1e-07 30.0 16.7 0.044 14.7 0.0 6.1 6 2 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KDO18968.1 - 0.0012 17.7 0.1 0.017 13.9 0.0 2.6 2 1 0 2 2 2 1 Nup133 N terminal like ABC_membrane PF00664.23 KDO18969.1 - 1.3e-51 175.8 12.3 9.8e-37 127.1 3.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO18969.1 - 4.9e-49 166.4 0.0 2.3e-28 99.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO18969.1 - 4.4e-12 45.9 3.3 0.0081 15.6 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO18969.1 - 3.1e-06 26.8 0.2 0.064 13.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO18969.1 - 3.2e-06 27.2 0.1 0.042 13.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KDO18969.1 - 0.00017 21.5 0.6 0.19 11.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO18969.1 - 0.00018 21.5 0.5 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO18969.1 - 0.00026 21.4 6.9 0.057 13.8 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain T2SSE PF00437.20 KDO18969.1 - 0.00035 19.7 0.2 0.29 10.1 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_22 PF13401.6 KDO18969.1 - 0.00072 19.8 1.6 0.19 12.0 0.1 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KDO18969.1 - 0.0013 18.0 0.1 1 8.6 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 KDO18969.1 - 0.0017 18.1 1.4 2.2 8.0 0.0 3.4 4 0 0 4 4 4 1 IstB-like ATP binding protein Dynamin_N PF00350.23 KDO18969.1 - 0.0029 17.7 3.3 0.48 10.5 0.1 2.6 3 0 0 3 3 2 2 Dynamin family AAA_23 PF13476.6 KDO18969.1 - 0.013 16.0 0.0 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KDO18969.1 - 0.017 14.7 1.3 0.81 9.3 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KDO18969.1 - 0.02 15.0 3.2 0.093 12.8 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KDO18969.1 - 0.022 15.3 0.1 4.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KDO18969.1 - 0.022 13.9 0.5 1.1 8.4 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.12 KDO18969.1 - 0.024 14.6 2.0 0.37 10.7 0.0 3.0 3 0 0 3 3 2 0 NACHT domain AAA_7 PF12775.7 KDO18969.1 - 0.024 14.2 0.1 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KDO18969.1 - 0.024 14.8 1.0 0.58 10.3 0.2 2.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO18969.1 - 0.036 14.3 0.1 7.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KDO18969.1 - 0.038 13.8 0.4 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KDO18969.1 - 0.043 13.5 3.1 7.9 6.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KDO18969.1 - 0.053 12.5 0.6 0.25 10.3 0.2 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KDO18969.1 - 0.057 13.4 0.2 5.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KDO18969.1 - 0.11 11.4 2.2 6.9 5.5 0.0 2.5 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain 60KD_IMP PF02096.20 KDO18969.1 - 0.12 12.2 0.3 1 9.2 0.1 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein FtsK_SpoIIIE PF01580.18 KDO18969.1 - 0.14 11.5 1.5 5.8 6.2 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 KDO18969.1 - 0.16 11.1 0.2 0.82 8.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) S-AdoMet_synt_C PF02773.16 KDO18969.1 - 0.18 11.8 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain DUF3177 PF11375.8 KDO18969.1 - 0.18 11.5 3.6 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) Tcp11 PF05794.13 KDO18969.1 - 0.24 10.4 0.2 0.76 8.8 0.1 1.9 3 0 0 3 3 3 0 T-complex protein 11 IIGP PF05049.13 KDO18969.1 - 0.32 10.0 0.5 3.6 6.5 0.2 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NTPase_1 PF03266.15 KDO18969.1 - 0.63 9.9 2.8 31 4.5 0.1 3.5 4 0 0 4 4 4 0 NTPase SAP PF02037.27 KDO18972.1 - 0.13 12.0 0.7 14 5.6 0.1 2.2 2 0 0 2 2 2 0 SAP domain Smg8_Smg9 PF10220.9 KDO18973.1 - 4.6e-30 104.7 3.2 3.1e-16 58.9 0.1 4.2 4 1 0 4 4 4 3 Smg8_Smg9 CTI PF06934.11 KDO18973.1 - 0.14 10.7 0.1 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) zf-RING_2 PF13639.6 KDO18975.1 - 8.3e-12 45.2 12.0 8.3e-12 45.2 12.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KDO18975.1 - 4.7e-08 32.6 9.8 4.7e-08 32.6 9.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO18975.1 - 8.9e-07 28.7 12.1 8.9e-07 28.7 12.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO18975.1 - 1e-06 28.9 11.8 4.8e-06 26.7 11.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO18975.1 - 4.3e-06 26.5 11.2 4.3e-06 26.5 11.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO18975.1 - 2.2e-05 24.3 9.6 4.8e-05 23.2 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO18975.1 - 0.00073 19.5 10.5 0.0016 18.4 10.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO18975.1 - 0.0008 19.2 8.3 0.0018 18.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO18975.1 - 0.018 14.9 10.7 0.035 13.9 10.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO18975.1 - 0.29 11.2 7.3 0.82 9.8 7.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO18975.1 - 0.61 9.7 10.3 0.15 11.7 7.2 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KDO18975.1 - 4 7.7 9.6 16 5.7 9.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain NA37 PF04245.13 KDO18976.1 - 0.025 14.1 0.4 0.025 14.1 0.4 2.7 2 1 1 3 3 3 0 37-kD nucleoid-associated bacterial protein DUF16 PF01519.16 KDO18976.1 - 0.31 11.6 10.9 1.6 9.3 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF16 RecC_C PF17946.1 KDO18976.1 - 0.39 10.5 2.9 0.34 10.7 0.2 2.0 2 0 0 2 2 2 0 RecC C-terminal domain PIH1_CS PF18201.1 KDO18977.1 - 1.5e-07 31.7 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain FOP_dimer PF09398.10 KDO18979.1 - 9.8e-13 48.2 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KDO18979.1 - 4.6e-12 44.7 0.1 6.9e-12 44.2 0.1 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 KDO18979.1 - 0.0021 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 LisH NARP1 PF12569.8 KDO18981.1 - 0.97 8.3 13.3 1.1 8.1 13.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PT PF04886.12 KDO18982.1 - 2.4e-12 46.2 47.6 1.3e-06 27.8 19.4 5.2 2 2 1 3 3 3 2 PT repeat CAP PF00188.26 KDO18982.1 - 2.7e-09 37.9 2.4 6e-09 36.8 2.4 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PT PF04886.12 KDO18983.1 - 1.5e-23 82.0 67.1 1.8e+04 -15.1 67.1 4.9 1 1 0 1 1 1 0 PT repeat Zip PF02535.22 KDO18983.1 - 8.9 5.4 6.7 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter LRR_8 PF13855.6 KDO18985.1 - 2.1e-10 40.2 3.6 8.2e-07 28.7 0.6 3.2 1 1 2 3 3 3 3 Leucine rich repeat Notch PF00066.17 KDO18985.1 - 1.7e-06 28.4 8.8 4e-06 27.2 8.8 1.6 1 0 0 1 1 1 1 LNR domain LRR_4 PF12799.7 KDO18985.1 - 0.00078 19.8 11.0 0.27 11.7 0.0 4.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO18985.1 - 2 9.3 9.1 40 5.3 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat DUF3678 PF12435.8 KDO18985.1 - 3.3 7.2 8.2 0.17 11.3 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) LRR_8 PF13855.6 KDO18987.1 - 1.1e-15 57.1 2.3 4.7e-09 35.9 0.1 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO18987.1 - 1.2e-10 41.4 1.0 1.4e-05 25.3 0.1 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO18987.1 - 0.00095 19.6 12.9 0.00095 19.6 12.9 1.9 2 0 0 2 2 2 1 LNR domain LRR_9 PF14580.6 KDO18987.1 - 0.0029 17.1 0.1 0.0054 16.2 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Rhomboid PF01694.22 KDO18987.1 - 1.2 9.1 7.3 0.15 12.1 1.7 2.2 3 0 0 3 3 3 0 Rhomboid family LRR_8 PF13855.6 KDO18989.1 - 7.6e-12 44.8 13.8 5.9e-06 25.9 1.2 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO18989.1 - 0.0001 22.6 4.2 0.0071 16.7 0.4 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO18989.1 - 0.00027 21.3 14.7 0.00059 20.2 14.7 1.6 1 0 0 1 1 1 1 LNR domain LRR_1 PF00560.33 KDO18989.1 - 0.14 12.8 1.2 41 5.3 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat TPR_12 PF13424.6 KDO18991.1 - 1.4e-17 63.7 5.0 7.5e-05 23.0 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO18991.1 - 3.1e-09 36.4 0.2 0.001 18.8 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO18991.1 - 0.0021 18.0 0.5 3.8 7.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO18991.1 - 0.0059 16.7 0.0 0.16 12.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO18991.1 - 0.014 15.2 0.1 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 KDO18992.1 - 1.6e-61 204.8 25.2 7.4e-19 68.1 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO18992.1 - 6.8e-55 182.8 15.7 9.9e-14 51.5 0.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO18992.1 - 1.7e-45 155.5 0.0 2.4e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 KDO18992.1 - 5.3e-43 144.5 14.8 2.6e-12 46.7 0.1 7.7 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO18992.1 - 5.5e-42 143.8 0.0 8.2e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KDO18992.1 - 8.8e-39 127.1 9.5 8.1e-06 25.8 0.0 9.0 9 0 0 9 9 8 8 Ankyrin repeat Ank PF00023.30 KDO18992.1 - 2.2e-32 110.1 17.2 2.1e-05 24.7 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Kinase-like PF14531.6 KDO18992.1 - 0.0019 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO18992.1 - 0.0064 15.3 1.3 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO18992.1 - 0.045 12.7 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO18992.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO18992.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RanBP PF00641.18 KDO18992.1 - 0.087 12.2 2.7 0.16 11.3 2.7 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others TPR_12 PF13424.6 KDO18993.1 - 3.4e-12 46.5 9.4 5.2e-08 33.1 1.1 4.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO18993.1 - 7.6e-06 25.6 6.7 0.00028 20.7 0.4 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO18993.1 - 0.00045 20.8 10.6 1.3 10.1 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO18993.1 - 0.0095 16.0 0.7 53 4.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO18993.1 - 0.1 13.1 2.1 7.9 7.1 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO18993.1 - 0.19 11.8 1.2 12 6.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO18993.1 - 2.3 9.0 12.0 0.83 10.4 2.6 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO18993.1 - 3.8 8.4 9.5 25 5.9 0.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GNVR PF13807.6 KDO18994.1 - 0.0042 17.0 0.2 0.0059 16.5 0.2 1.1 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase CMAS PF02353.20 KDO18995.1 - 5.9e-05 22.5 0.0 7.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MFS_2 PF13347.6 KDO18995.1 - 0.076 11.6 0.1 0.088 11.3 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Ras PF00071.22 KDO18996.1 - 7e-65 217.6 0.6 8.2e-65 217.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO18996.1 - 2.6e-35 121.3 0.2 3.8e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO18996.1 - 2.9e-17 62.6 0.1 3.8e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO18996.1 - 3.2e-07 30.1 0.4 8.4e-07 28.7 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO18996.1 - 2.4e-06 27.1 0.2 2.8e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KDO18996.1 - 0.00054 19.2 1.2 0.049 12.8 0.4 2.9 1 1 1 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KDO18996.1 - 0.00056 19.9 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KDO18996.1 - 0.00093 18.7 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO18996.1 - 0.0015 18.6 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ser_hydrolase PF06821.13 KDO18996.1 - 0.007 16.2 0.1 0.014 15.2 0.1 1.4 1 1 0 1 1 1 1 Serine hydrolase AAA PF00004.29 KDO18996.1 - 0.016 15.6 0.0 0.25 11.8 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KDO18996.1 - 0.071 12.6 0.2 0.33 10.5 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KDO18996.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KDO18996.1 - 0.079 12.2 0.1 0.19 11.0 0.1 1.6 1 1 0 1 1 1 0 Septin AAA_7 PF12775.7 KDO18996.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region WD40 PF00400.32 KDO18997.1 - 4.6e-50 166.5 18.9 2.3e-07 31.4 2.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO18997.1 - 1.2e-17 63.9 0.3 0.0063 16.8 0.0 6.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO18997.1 - 1e-06 28.3 0.0 0.1 11.9 0.0 3.2 1 1 2 3 3 3 3 WD40-like domain Nup160 PF11715.8 KDO18997.1 - 1.7e-06 27.0 1.5 0.035 12.8 0.0 4.0 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO18997.1 - 0.0086 15.1 4.8 0.13 11.2 1.0 3.8 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PKD PF00801.20 KDO18997.1 - 0.031 14.1 2.8 6.2 6.8 0.0 3.5 3 0 0 3 3 3 0 PKD domain Ank_4 PF13637.6 KDO18999.1 - 2.1e-25 88.8 1.2 1.8e-10 41.1 0.0 4.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO18999.1 - 2.6e-25 88.2 3.6 1.3e-08 35.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO18999.1 - 2e-22 79.6 0.4 1.1e-15 58.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO18999.1 - 4.6e-20 69.6 0.2 2e-07 30.8 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO18999.1 - 6.2e-17 61.2 0.8 8.8e-06 25.9 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat DUF4985 PF16373.5 KDO18999.1 - 0.026 15.0 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function RIO1 PF01163.22 KDO19000.1 - 6.9e-50 169.3 0.1 1.2e-49 168.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KDO19000.1 - 8.7e-34 115.6 0.2 3.8e-33 113.6 0.3 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KDO19000.1 - 2.7e-08 34.1 2.0 0.0032 17.4 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO19000.1 - 5.5e-06 25.9 0.3 0.00032 20.1 0.3 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KDO19000.1 - 0.00015 21.2 0.0 0.00088 18.7 0.0 2.0 1 1 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 KDO19000.1 - 0.077 12.6 1.0 0.29 10.7 0.2 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase PseudoU_synth_1 PF01416.20 KDO19000.1 - 0.15 12.6 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 tRNA pseudouridine synthase TPR_2 PF07719.17 KDO19001.1 - 1.1e-11 43.9 0.5 0.019 15.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO19001.1 - 5.6e-08 32.6 0.1 0.0096 16.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO19001.1 - 5.7e-08 32.3 3.1 4.5e-06 26.2 0.1 3.3 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 KDO19001.1 - 8.3e-08 32.6 11.8 3.3e-05 24.3 0.9 3.4 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19001.1 - 1.7e-06 27.6 0.2 0.035 13.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO19001.1 - 2e-06 27.9 2.4 2.4e-06 27.7 0.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KDO19001.1 - 3.5e-06 27.6 11.8 4.9e-05 23.9 2.9 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO19001.1 - 0.00019 22.0 12.7 0.0033 18.1 0.5 4.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO19001.1 - 0.0095 16.1 0.1 23 5.5 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO19001.1 - 0.1 13.3 5.2 2 9.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 KDO19001.1 - 0.58 10.2 3.6 0.94 9.5 0.2 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 KDO19001.1 - 1.8 8.8 15.7 0.69 10.1 4.7 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 KDO19002.1 - 1.3e-12 47.7 0.7 3e-12 46.5 0.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO19002.1 - 0.0022 18.2 0.1 0.0062 16.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF5133 PF17196.4 KDO19002.1 - 0.086 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) DUF1660 PF07874.11 KDO19002.1 - 0.092 13.3 2.7 35 5.0 0.0 3.5 3 0 0 3 3 3 0 Prophage protein (DUF1660) STAC2_u1 PF16664.5 KDO19002.1 - 1 9.8 7.2 0.2 12.1 0.5 2.7 3 0 0 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 WW PF00397.26 KDO19003.1 - 0.00032 20.7 0.1 0.00054 20.0 0.1 1.3 1 0 0 1 1 1 1 WW domain Ebola_NP PF05505.12 KDO19003.1 - 0.084 11.2 1.2 0.12 10.6 1.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein IQ PF00612.27 KDO19003.1 - 0.42 10.5 4.0 1.2 9.1 4.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Com_YlbF PF06133.11 KDO19003.1 - 2.2 8.9 7.5 16 6.2 6.2 2.3 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DEAD PF00270.29 KDO19004.1 - 6.6e-39 133.5 0.2 1.3e-38 132.5 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO19004.1 - 6.1e-24 84.5 0.0 3e-22 79.1 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KDO19004.1 - 5.1e-19 68.2 0.1 1.1e-18 67.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) UQ_con PF00179.26 KDO19005.1 - 2.6e-13 49.8 0.1 3.6e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_transf_22 PF03901.17 KDO19006.1 - 5.2e-86 289.5 21.0 6.2e-86 289.2 21.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EBV-NA3 PF05009.12 KDO19007.1 - 0.08 12.5 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Rieske PF00355.26 KDO19012.1 - 0.071 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain FAD_binding_2 PF00890.24 KDO19012.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF4371 PF14291.6 KDO19013.1 - 1.9e-05 24.5 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KDO19013.1 - 0.026 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Pkinase PF00069.25 KDO19014.1 - 4.1e-31 108.3 0.0 5.2e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19014.1 - 5.2e-27 94.8 0.0 6.2e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19014.1 - 0.00057 19.3 0.0 0.00071 19.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KDO19015.1 - 6.1e-34 117.6 0.0 9.7e-32 110.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19015.1 - 1.5e-32 112.9 0.0 3e-31 108.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19015.1 - 4.4e-05 22.9 0.0 5.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 KDO19015.1 - 0.032 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PIP49_C PF12260.8 KDO19015.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 KDO19015.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO19016.1 - 1.8e-21 76.7 0.0 2.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19016.1 - 2.5e-21 76.1 0.0 3.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO19016.1 - 0.0037 16.3 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain BT1 PF03092.16 KDO19017.1 - 7.5e-05 21.2 1.2 7.6e-05 21.1 0.7 1.4 1 1 0 1 1 1 1 BT1 family PUCC PF03209.15 KDO19017.1 - 0.00017 20.7 0.3 0.00028 20.0 0.3 1.3 1 0 0 1 1 1 1 PUCC protein DUF4474 PF14751.6 KDO19017.1 - 0.025 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) MadL PF03817.13 KDO19017.1 - 0.11 12.5 0.3 0.11 12.5 0.3 1.6 2 0 0 2 2 2 0 Malonate transporter MadL subunit Lipase_GDSL_2 PF13472.6 KDO19018.1 - 3.3e-24 86.3 0.2 4e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO19018.1 - 2.7e-14 53.6 0.0 4.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF459 PF04311.13 KDO19018.1 - 0.032 13.2 0.0 0.068 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF459) Filamin PF00630.19 KDO19019.1 - 4.5e-23 82.0 0.0 4.1e-07 30.8 0.0 6.5 6 1 0 6 6 6 3 Filamin/ABP280 repeat PA14 PF07691.12 KDO19019.1 - 6.4e-08 32.5 0.1 9.2e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 PA14 domain Invasin_D3 PF09134.10 KDO19019.1 - 4.8e-07 30.0 24.3 0.007 16.7 4.6 6.0 6 1 0 6 6 6 4 Invasin, domain 3 GLEYA PF10528.9 KDO19019.1 - 0.026 15.0 0.1 0.23 11.9 0.1 2.7 1 1 0 1 1 1 0 GLEYA domain Y_Y_Y PF07495.13 KDO19019.1 - 0.062 13.3 0.1 53 3.9 0.0 3.9 4 0 0 4 4 4 0 Y_Y_Y domain nlz1 PF12402.8 KDO19019.1 - 2.1 8.9 7.0 4.6 7.7 0.2 3.7 3 0 0 3 3 3 0 NocA-like zinc-finger protein 1 zf-TAZ PF02135.16 KDO19020.1 - 4.9e-30 103.8 67.4 1e-12 48.3 19.9 4.3 4 0 0 4 4 4 3 TAZ zinc finger KIX_2 PF16987.5 KDO19020.1 - 5.1e-16 58.4 2.7 8.7e-09 35.3 1.2 5.0 4 0 0 4 4 4 2 KIX domain KIX PF02172.16 KDO19020.1 - 4.6e-08 33.2 0.8 0.00083 19.6 0.2 2.9 2 0 0 2 2 2 2 KIX domain Med15 PF09606.10 KDO19020.1 - 0.00011 21.0 47.9 0.00011 21.0 47.9 4.1 2 1 2 4 4 4 3 ARC105 or Med15 subunit of Mediator complex non-fungal zf_CCCH_4 PF18345.1 KDO19020.1 - 0.077 13.1 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-TAZ PF02135.16 KDO19023.1 - 1.2e-12 48.1 16.0 1.2e-12 48.1 16.0 1.6 2 0 0 2 2 2 1 TAZ zinc finger Cytadhesin_P30 PF07271.11 KDO19023.1 - 0.0051 16.4 30.8 0.0072 15.9 30.8 1.2 1 0 0 1 1 1 1 Cytadhesin P30/P32 Menin PF05053.13 KDO19023.1 - 0.22 9.9 0.7 0.27 9.5 0.7 1.1 1 0 0 1 1 1 0 Menin HAT_KAT11 PF08214.11 KDO19024.1 - 1.5e-28 100.1 2.4 2.6e-27 96.0 2.4 2.4 1 1 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 KDO19024.1 - 4.1e-20 71.7 3.0 6.7e-19 67.8 0.0 2.8 3 0 0 3 3 3 1 Bromodomain zf-TAZ PF02135.16 KDO19024.1 - 4e-13 49.6 12.6 4e-13 49.6 12.6 4.0 4 0 0 4 4 4 1 TAZ zinc finger ZZ PF00569.17 KDO19024.1 - 1.1e-10 41.1 9.9 1.1e-10 41.1 9.9 4.7 5 1 0 5 5 5 1 Zinc finger, ZZ type PHD PF00628.29 KDO19024.1 - 0.0001 22.1 6.6 0.0001 22.1 6.6 5.2 4 1 0 4 4 4 1 PHD-finger DUF902 PF06001.13 KDO19024.1 - 0.01 16.3 6.5 0.036 14.5 6.5 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) Baculo_IE-1 PF05290.11 KDO19024.1 - 0.13 12.3 8.8 0.038 13.9 1.2 3.2 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) Sirohm_synth_C PF14823.6 KDO19024.1 - 0.61 9.8 3.2 12 5.6 0.2 3.9 4 0 0 4 4 4 0 Sirohaem biosynthesis protein C-terminal YebO PF13974.6 KDO19024.1 - 5.2 7.2 7.5 45 4.2 7.5 2.7 1 1 0 1 1 1 0 YebO-like protein MFS_1 PF07690.16 KDO19025.1 - 2.5e-20 72.7 31.1 2.5e-20 72.7 31.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Oxidored_FMN PF00724.20 KDO19026.1 - 4e-12 46.0 0.0 4.3e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KDO19027.1 - 2.1e-78 264.0 0.0 3.6e-78 263.2 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 KDO19028.1 - 2.1e-38 132.4 33.5 7.5e-26 91.0 4.7 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO19028.1 - 2.1e-27 96.0 48.6 3.7e-24 85.3 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sipho_tail PF05709.11 KDO19028.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein Mito_carr PF00153.27 KDO19029.1 - 4.2e-48 161.2 1.4 2.6e-21 75.3 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Ricin_B_lectin PF00652.22 KDO19029.1 - 6.6e-05 23.2 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Pkinase_Tyr PF07714.17 KDO19030.1 - 4.1e-50 170.5 0.0 5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19030.1 - 3e-48 164.5 0.0 4.1e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO19030.1 - 0.00037 19.9 0.0 0.00058 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SKG6 PF08693.10 KDO19030.1 - 0.0058 16.0 0.3 0.012 15.0 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 KDO19030.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO19030.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO19030.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19030.1 - 0.15 11.0 0.0 0.32 9.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Wbp11 PF09429.10 KDO19031.1 - 3e-11 43.6 13.4 3e-11 43.6 13.4 2.3 1 1 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.7 KDO19031.1 - 1.3e-07 32.2 1.1 1.3e-07 32.2 1.1 2.1 2 1 0 2 2 2 1 mRNA biogenesis factor Atg14 PF10186.9 KDO19031.1 - 0.095 11.8 3.8 0.12 11.5 3.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NYD-SP12_N PF15015.6 KDO19031.1 - 0.16 10.3 6.0 0.18 10.1 6.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal EMC3_TMCO1 PF01956.16 KDO19031.1 - 1.4 8.6 3.3 16 5.2 0.0 2.1 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PEP-utilisers_N PF05524.13 KDO19031.1 - 2.4 8.4 7.5 77 3.5 7.5 2.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Glucan_synthase PF02364.15 KDO19032.1 - 1.4e-187 625.5 6.8 2.7e-165 551.8 2.9 2.6 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO19032.1 - 1.4e-23 83.7 0.3 1.5e-21 77.1 0.3 2.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Orthoreo_P10 PF07204.11 KDO19032.1 - 0.016 15.1 0.0 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EF-hand_5 PF13202.6 KDO19032.1 - 0.07 12.6 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 EF hand MIT PF04212.18 KDO19032.1 - 0.35 11.0 2.6 0.24 11.5 0.2 1.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain WW PF00397.26 KDO19033.1 - 1.2e-17 63.7 9.7 1.3e-08 34.8 1.7 2.5 2 0 0 2 2 2 2 WW domain zf-B_box PF00643.24 KDO19033.1 - 0.00036 20.6 4.1 0.00036 20.6 4.1 2.8 2 1 1 3 3 3 2 B-box zinc finger PQQ PF01011.21 KDO19033.1 - 0.011 15.6 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Glyco_hyd_101C PF17451.2 KDO19033.1 - 0.031 14.6 0.8 0.87 9.9 0.3 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Minor_tail_Z PF06763.11 KDO19033.1 - 0.2 11.5 3.0 5.8 6.7 0.5 2.4 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Myb_DNA-binding PF00249.31 KDO19034.1 - 7.5e-40 134.9 14.0 1.1e-13 51.1 0.8 4.3 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO19034.1 - 5.4e-36 122.6 6.6 1e-16 60.9 0.2 4.3 2 1 2 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 KDO19034.1 - 0.0039 17.2 0.0 6.2 6.9 0.0 3.4 3 1 1 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 KDO19034.1 - 0.016 15.6 7.1 3.7 8.0 0.1 3.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 KDO19034.1 - 0.021 14.9 3.8 14 5.8 0.1 3.5 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 KDO19034.1 - 0.059 13.3 0.1 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Myb DNA-binding like Sporozoite_P67 PF05642.11 KDO19034.1 - 0.78 7.7 5.6 1.1 7.2 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KDO19034.1 - 3.4 6.9 10.1 5.4 6.2 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_6 PF13516.6 KDO19035.1 - 7.7e-14 50.5 0.8 0.0081 16.1 0.0 5.9 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KDO19035.1 - 1.6e-07 31.5 0.6 0.0012 19.1 0.0 3.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19035.1 - 6.8e-05 22.5 5.4 0.0056 16.4 0.0 4.0 4 2 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 KDO19035.1 - 0.0003 20.3 0.5 0.0078 15.7 0.2 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KDO19035.1 - 0.05 14.2 0.2 50 5.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat HECT PF00632.25 KDO19036.1 - 9.1e-68 229.0 0.0 1.1e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FIBP PF05427.11 KDO19038.1 - 2.9e-69 234.1 0.0 1.2e-53 182.7 0.0 2.1 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) PUB PF09409.10 KDO19039.1 - 2.6e-14 52.9 0.0 6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 PUB domain Pex14_N PF04695.13 KDO19039.1 - 1.6e-11 45.1 4.0 4.8e-11 43.6 4.0 2.0 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 KDO19039.1 - 4.9e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) V-SNARE PF05008.15 KDO19039.1 - 0.03 14.7 3.0 0.078 13.4 3.0 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Xpo1 PF08389.12 KDO19040.1 - 0.0027 17.8 1.4 0.33 11.0 0.1 3.8 3 1 1 4 4 4 1 Exportin 1-like protein VCPO_N PF17897.1 KDO19040.1 - 0.36 10.6 2.4 0.74 9.6 1.0 2.0 2 0 0 2 2 2 0 Vanadium chloroperoxidase N-terminal domain SUI1 PF01253.22 KDO19041.1 - 2.5e-20 72.8 0.1 5.5e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 RXT2_N PF08595.11 KDO19041.1 - 0.0028 17.7 1.7 0.0057 16.7 1.7 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal GCIP PF13324.6 KDO19041.1 - 0.055 13.1 0.7 0.078 12.6 0.7 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting eIF-3c_N PF05470.12 KDO19041.1 - 0.11 10.8 0.5 0.14 10.4 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CENP-B_dimeris PF09026.10 KDO19041.1 - 0.15 12.5 10.9 0.28 11.6 10.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO19041.1 - 0.34 10.2 5.7 0.52 9.6 5.7 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 KDO19041.1 - 0.56 10.5 10.9 0.37 11.0 7.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KDO19041.1 - 0.84 7.7 6.5 0.26 9.3 3.8 1.5 2 0 0 2 2 2 0 DNA polymerase phi DUF2457 PF10446.9 KDO19041.1 - 0.9 8.6 8.8 1.4 8.0 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KDO19041.1 - 1.5 7.0 3.3 2.6 6.2 3.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 KDO19041.1 - 2.7 7.6 11.3 0.39 10.4 6.8 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AFG1_ATPase PF03969.16 KDO19042.1 - 1.6e-100 336.5 0.8 2.1e-100 336.2 0.8 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.6 KDO19042.1 - 0.001 19.1 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain EF-hand_7 PF13499.6 KDO19042.1 - 0.0017 18.8 0.1 0.0078 16.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Bac_DnaA PF00308.18 KDO19042.1 - 0.0025 17.7 3.2 0.094 12.5 0.1 3.0 3 1 0 3 3 3 1 Bacterial dnaA protein AAA_16 PF13191.6 KDO19042.1 - 0.0047 17.3 0.4 2 8.8 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KDO19042.1 - 0.031 14.7 0.1 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KDO19042.1 - 0.046 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin EF-hand_1 PF00036.32 KDO19042.1 - 0.05 13.2 1.3 0.4 10.3 0.1 3.2 4 0 0 4 4 4 0 EF hand AAA_22 PF13401.6 KDO19042.1 - 0.059 13.7 0.0 0.42 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain EF-hand_6 PF13405.6 KDO19042.1 - 0.11 12.5 0.2 0.78 9.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain GBP PF02263.19 KDO19043.1 - 0.008 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain zf-C2H2_6 PF13912.6 KDO19044.1 - 0.085 12.9 0.1 0.085 12.9 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KDO19044.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KDO19044.1 - 0.4 11.7 0.2 0.4 11.7 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_S8 PF00082.22 KDO19045.1 - 5.9e-41 140.7 1.2 1.4e-40 139.5 1.2 1.6 1 1 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 KDO19046.1 - 2e-36 125.8 3.5 2e-36 125.8 3.5 2.8 4 0 0 4 4 4 1 Subtilase family Ricin_B_lectin PF00652.22 KDO19046.1 - 3.3e-25 88.8 9.6 1.2e-12 48.2 1.3 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19046.1 - 4.7e-09 36.8 5.7 0.002 18.8 0.3 3.9 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Peptidase_S8 PF00082.22 KDO19047.1 - 5.2e-36 124.4 3.6 1.1e-35 123.4 3.6 1.6 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 KDO19047.1 - 9.9e-26 90.5 3.3 7.7e-12 45.6 2.4 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19047.1 - 3e-09 37.5 6.3 0.00014 22.6 1.5 4.2 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO19047.1 - 0.034 13.7 2.8 0.038 13.6 0.1 2.2 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Peptidase_S8 PF00082.22 KDO19048.1 - 2.2e-28 99.4 5.7 4e-28 98.5 5.7 1.4 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 KDO19048.1 - 2.1e-25 89.4 7.0 3.7e-12 46.6 2.3 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19048.1 - 1.7e-08 35.0 10.6 0.0012 19.5 2.3 4.1 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Lyase_aromatic PF00221.19 KDO19049.1 - 0.21 10.2 3.0 0.53 8.9 1.8 1.9 2 0 0 2 2 2 0 Aromatic amino acid lyase Med3 PF11593.8 KDO19049.1 - 2.2 7.4 6.3 2.9 7.0 6.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_S8 PF00082.22 KDO19051.1 - 3.2e-32 112.0 3.7 2.8e-31 108.9 2.2 2.8 2 1 0 2 2 2 1 Subtilase family Ricin_B_lectin PF00652.22 KDO19051.1 - 8.7e-25 87.4 12.1 1.6e-12 47.8 1.8 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19051.1 - 6.9e-09 36.3 7.2 0.00093 19.9 0.2 3.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like PAN_4 PF14295.6 KDO19052.1 - 2.4e-08 33.8 5.5 3.6e-08 33.2 5.5 1.3 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KDO19052.1 - 8.6e-05 22.4 3.7 0.00011 22.1 3.7 1.1 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KDO19052.1 - 0.016 15.0 2.4 0.02 14.7 2.4 1.2 1 0 0 1 1 1 0 PAN-like domain Na_H_Exchanger PF00999.21 KDO19053.1 - 5.7e-63 213.0 40.6 7.2e-63 212.7 40.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-TAZ PF02135.16 KDO19054.1 - 0.0017 18.8 11.1 0.0062 17.0 11.1 1.9 1 1 0 1 1 1 1 TAZ zinc finger DSPn PF14671.6 KDO19055.1 - 2.4e-29 102.6 0.3 4e-29 101.9 0.2 1.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KDO19055.1 - 2.4e-14 53.3 0.0 9.4e-13 48.1 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO19055.1 - 4.4e-05 23.2 0.0 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO19055.1 - 0.0002 21.5 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KDO19055.1 - 0.0081 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PapJ PF14855.6 KDO19055.1 - 0.22 11.2 0.2 0.38 10.4 0.2 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone PDCD7 PF16021.5 KDO19058.1 - 0.026 13.7 2.1 0.028 13.5 2.1 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 Ago_PAZ PF18309.1 KDO19058.1 - 0.048 14.3 0.6 1.4 9.7 0.1 2.1 1 1 1 2 2 2 0 Argonaute PAZ domain IBR PF01485.21 KDO19060.1 - 4.3e-05 23.7 34.0 0.00023 21.3 2.6 3.9 3 2 1 4 4 4 3 IBR domain, a half RING-finger domain PolC_DP2 PF03833.13 KDO19060.1 - 8.1 4.2 6.0 11 3.8 6.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DLIC PF05783.11 KDO19061.1 - 8.3e-10 38.1 0.0 1e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 KDO19061.1 - 1.1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO19061.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 KDO19061.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KDO19061.1 - 0.11 12.3 2.8 0.21 11.4 0.1 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KDO19061.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 KDO19061.1 - 0.22 11.2 0.0 0.33 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PQQ_3 PF13570.6 KDO19062.1 - 0.035 14.6 9.9 11 6.6 0.4 4.6 4 1 0 4 4 4 0 PQQ-like domain Ank_2 PF12796.7 KDO19063.1 - 3.2e-32 111.0 5.3 1.7e-15 57.4 0.7 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19063.1 - 1.6e-21 76.4 1.1 8.3e-09 35.8 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19063.1 - 1.6e-19 67.9 0.8 0.00096 19.4 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KDO19063.1 - 8.2e-17 60.8 11.0 0.00056 20.2 0.4 6.0 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO19063.1 - 4.2e-14 52.4 7.3 0.0004 20.6 0.2 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19064.1 - 1.8e-82 272.0 12.1 1.4e-19 70.4 0.3 7.3 2 1 4 7 7 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KDO19064.1 - 1.4e-72 237.2 35.6 1.8e-07 31.3 0.0 13.5 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.6 KDO19064.1 - 1.1e-69 230.0 14.9 9.5e-08 32.4 0.1 11.5 3 3 9 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19064.1 - 2.4e-61 203.0 36.3 2.5e-10 40.4 0.1 10.0 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19064.1 - 8.2e-60 191.7 16.1 7.7e-05 22.8 0.0 13.8 14 0 0 14 14 14 12 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO19064.1 - 7.5e-44 150.0 0.0 1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19064.1 - 3.3e-43 148.0 0.0 4.8e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO19064.1 - 0.00054 19.0 0.1 0.00073 18.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO19064.1 - 0.0079 15.0 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase GATase_7 PF13537.6 KDO19064.1 - 0.082 12.8 0.0 68 3.4 0.0 4.0 3 1 0 3 3 3 0 Glutamine amidotransferase domain Sbt_1 PF05982.12 KDO19064.1 - 0.11 11.7 1.2 2.1 7.5 0.2 2.7 2 1 0 3 3 3 0 Na+-dependent bicarbonate transporter superfamily LRR_6 PF13516.6 KDO19066.1 - 0.0046 16.9 4.6 5.1 7.4 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KDO19066.1 - 0.015 15.7 0.0 1 9.9 0.0 3.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) PilS PF08805.11 KDO19066.1 - 0.17 11.7 1.5 0.38 10.6 0.7 1.8 1 1 1 2 2 2 0 PilS N terminal Mersacidin PF16934.5 KDO19066.1 - 0.18 11.6 3.1 1 9.2 3.1 2.3 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) DnaJ PF00226.31 KDO19067.1 - 2.4e-19 69.2 0.1 3.7e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 KDO19068.1 - 8.5e-08 31.9 10.8 8.5e-08 31.9 10.8 4.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO19068.1 - 0.00077 19.3 7.0 0.00077 19.3 7.0 3.5 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO19068.1 - 0.0035 17.2 8.7 0.0035 17.2 8.7 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 KDO19068.1 - 0.02 15.4 3.2 0.02 15.4 3.2 5.7 7 0 0 7 7 7 0 Zinc finger, C2H2 type PP2C PF00481.21 KDO19069.1 - 5e-41 141.0 0.0 7.7e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO19069.1 - 0.0011 18.7 2.7 0.0035 17.0 2.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO19069.1 - 0.031 14.2 0.4 0.093 12.6 0.4 1.8 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Bactofilin PF04519.13 KDO19070.1 - 4.2e-17 62.2 1.7 7.1e-17 61.5 1.7 1.4 1 0 0 1 1 1 1 Polymer-forming cytoskeletal DTHCT PF08070.11 KDO19070.1 - 5 7.9 6.6 0.27 12.0 0.3 2.1 3 0 0 3 3 3 0 DTHCT (NUC029) region SPX PF03105.19 KDO19071.1 - 2e-13 51.0 0.1 2.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 SPX domain GDPD PF03009.17 KDO19071.1 - 2e-09 37.6 0.1 0.00045 20.0 0.1 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_4 PF15227.6 KDO19071.1 - 4.7e-08 33.1 11.9 8.5e-08 32.2 11.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KDO19071.1 - 7.1e-08 32.7 12.9 1.3e-07 31.9 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO19071.1 - 9.1e-07 28.8 9.3 2.2e-06 27.6 9.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO19071.1 - 9.7e-07 28.5 12.9 1.7e-06 27.7 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO19071.1 - 1.1e-05 25.2 8.8 1.9e-05 24.4 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO19071.1 - 1.6e-05 24.7 12.9 2.6e-05 24.0 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO19071.1 - 8.1e-05 22.5 11.0 0.00014 21.7 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KDO19071.1 - 0.013 15.2 2.9 0.013 15.2 2.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KDO19071.1 - 0.055 13.3 14.3 0.27 11.1 14.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO19071.1 - 0.11 12.7 3.7 0.19 11.9 3.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KDO19071.1 - 3.6 7.5 6.3 7.3 6.5 6.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PH PF00169.29 KDO19072.1 - 1.6e-09 38.2 1.0 1.2e-08 35.4 1.0 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO19072.1 - 0.00022 21.5 0.0 0.035 14.4 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KDO19072.1 - 0.0047 17.3 2.3 0.021 15.3 2.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Tuberculin PF12198.8 KDO19072.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Theoretical tuberculin protein Mcp5_PH PF12814.7 KDO19072.1 - 0.16 12.1 0.3 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology TMF_TATA_bd PF12325.8 KDO19073.1 - 1.6 9.0 88.5 0.029 14.6 9.6 7.8 1 1 4 7 7 7 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 KDO19073.1 - 4.2 4.8 109.0 0.19 9.2 43.4 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) FAST_2 PF08368.12 KDO19073.1 - 8.1 7.3 8.9 3.5 8.5 0.2 4.2 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 2 PIRT PF15099.6 KDO19077.1 - 0.24 11.0 1.0 0.32 10.6 1.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Ricin_B_lectin PF00652.22 KDO19078.1 - 0.00016 21.9 2.2 0.00024 21.3 2.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19078.1 - 0.0043 17.8 0.2 0.0043 17.8 0.2 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KDO19079.1 - 0.00055 20.2 0.0 0.00093 19.5 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19079.1 - 0.0026 18.4 0.0 0.0062 17.2 0.0 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Mce4_CUP1 PF11887.8 KDO19080.1 - 0.013 15.0 0.2 0.021 14.3 0.2 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative STAT_alpha PF01017.20 KDO19080.1 - 0.15 11.9 0.6 1.8 8.4 0.6 2.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF1843 PF08898.10 KDO19080.1 - 2.7 8.6 4.5 51 4.5 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Ricin_B_lectin PF00652.22 KDO19081.1 - 1.7e-06 28.3 1.0 2.8e-06 27.6 1.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19081.1 - 0.0033 18.1 0.1 0.0033 18.1 0.1 2.2 3 1 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like G-patch PF01585.23 KDO19082.1 - 2.3e-17 62.6 0.1 3.5e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KDO19082.1 - 1.7e-07 31.2 0.1 1.7e-07 31.2 0.1 1.7 2 0 0 2 2 2 1 G-patch domain LRR_4 PF12799.7 KDO19083.1 - 0.091 13.2 0.0 6.3 7.4 0.0 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) MMTV_SAg PF01054.17 KDO19084.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Mouse mammary tumour virus superantigen DUF815 PF05673.13 KDO19087.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) LRR_4 PF12799.7 KDO19087.1 - 0.13 12.8 0.3 2.3 8.8 0.3 3.0 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) SR-25 PF10500.9 KDO19088.1 - 0.21 11.2 4.6 0.25 10.9 4.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-HC5HC2H PF13771.6 KDO19089.1 - 0.0089 16.3 0.4 0.018 15.2 0.4 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KDO19089.1 - 0.055 13.6 0.5 0.21 11.7 0.9 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.8 KDO19089.1 - 0.056 13.6 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KDO19089.1 - 0.098 12.6 1.2 0.21 11.5 0.7 1.9 1 1 0 1 1 1 0 PHD-finger GMC_oxred_C PF05199.13 KDO19090.1 - 2.6e-14 54.0 1.5 3.3e-14 53.6 1.5 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DEAD PF00270.29 KDO19091.1 - 3.4e-44 150.7 0.0 5.3e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO19091.1 - 1.4e-31 109.1 0.0 3.5e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO19091.1 - 0.0021 18.1 0.0 0.0046 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KDO19091.1 - 0.019 15.3 0.1 0.083 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Metal_CEHH PF14455.6 KDO19091.1 - 0.053 13.1 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Predicted metal binding domain UTP25 PF06862.12 KDO19091.1 - 0.13 11.0 0.0 0.75 8.5 0.0 2.2 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Peptidase_C69 PF03577.15 KDO19092.1 - 7.6e-42 143.6 7.7 6.2e-41 140.6 7.7 2.0 1 1 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 KDO19092.1 - 0.039 13.8 0.1 0.099 12.5 0.1 1.7 1 0 0 1 1 1 0 Phage Head-Tail Attachment DAP_epimerase PF01678.19 KDO19093.1 - 8.5e-42 142.2 2.1 1.3e-21 77.0 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase GFA PF04828.14 KDO19094.1 - 1.8e-08 34.6 1.2 1.8e-08 34.6 1.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PLAC8 PF04749.17 KDO19095.1 - 2e-20 73.6 16.1 2.6e-20 73.2 16.1 1.1 1 0 0 1 1 1 1 PLAC8 family DUF4491 PF14898.6 KDO19095.1 - 0.056 13.9 0.9 0.12 12.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) PLAC8 PF04749.17 KDO19096.1 - 5e-19 69.2 11.9 7.8e-19 68.5 11.9 1.3 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KDO19097.1 - 1.5e-19 70.8 21.6 2.6e-19 70.0 21.6 1.4 1 1 0 1 1 1 1 PLAC8 family NDC10_II PF16787.5 KDO19098.1 - 1.1e-25 90.3 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 AIP3 PF03915.13 KDO19098.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 NDC10_II PF16787.5 KDO19099.1 - 1.6e-26 93.1 0.0 2.1e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Peptidase_C69 PF03577.15 KDO19100.1 - 8.7e-36 123.7 0.1 1.8e-35 122.7 0.1 1.4 1 1 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 KDO19100.1 - 0.073 13.0 0.3 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Phage Head-Tail Attachment Period_C PF12114.8 KDO19101.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF3410 PF11890.8 KDO19102.1 - 0.0027 17.4 0.3 0.053 13.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3410) betaPIX_CC PF16523.5 KDO19102.1 - 0.03 14.1 0.6 5.8 6.8 0.1 2.7 3 0 0 3 3 3 0 betaPIX coiled coil DUF2046 PF09755.9 KDO19105.1 - 0.066 12.4 1.4 0.11 11.8 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) PRK PF00485.18 KDO19106.1 - 3.9e-07 30.0 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KDO19106.1 - 3.5e-05 24.0 0.0 6.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO19106.1 - 0.00025 21.6 0.0 0.00036 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO19106.1 - 0.00035 19.7 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KDO19106.1 - 0.0058 17.1 0.0 0.0082 16.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 KDO19106.1 - 0.0063 16.6 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 KDO19106.1 - 0.0075 15.6 0.0 0.015 14.6 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KDO19106.1 - 0.01 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO19106.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KDO19106.1 - 0.018 15.0 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 KDO19106.1 - 0.026 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KDO19106.1 - 0.028 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KDO19106.1 - 0.03 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KDO19106.1 - 0.036 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 KDO19106.1 - 0.043 14.2 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KDO19106.1 - 0.047 14.0 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO19106.1 - 0.048 13.9 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tubulin_2 PF13809.6 KDO19106.1 - 0.056 12.6 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like NACHT PF05729.12 KDO19106.1 - 0.056 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KDO19106.1 - 0.071 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KDO19106.1 - 0.074 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase NTPase_1 PF03266.15 KDO19106.1 - 0.094 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KDO19106.1 - 0.097 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KDO19106.1 - 0.11 13.0 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KDO19106.1 - 0.12 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KDO19106.1 - 0.16 12.3 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 KDO19106.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase KAP_NTPase PF07693.14 KDO19106.1 - 0.21 10.8 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Ribosomal_L19e PF01280.20 KDO19108.1 - 2.6e-64 215.6 11.0 2.6e-64 215.6 11.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e GST_C_3 PF14497.6 KDO19109.1 - 1.1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO19109.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF998 PF06197.13 KDO19109.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) SET PF00856.28 KDO19110.1 - 7.8e-13 49.2 0.0 1.6e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 KDO19110.1 - 0.029 14.2 0.2 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 F-box-like tRNA-synt_His PF13393.6 KDO19111.1 - 7.6e-44 150.2 0.0 1.3e-43 149.4 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 KDO19111.1 - 1.4e-13 51.2 0.0 2e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KDO19111.1 - 1.4e-10 41.2 0.0 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 KDO19111.1 - 0.0023 17.5 0.0 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) MukB PF04310.12 KDO19111.1 - 0.14 12.0 0.2 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 MukB N-terminal Terpene_synth_C PF03936.16 KDO19112.1 - 0.05 12.9 0.1 0.068 12.5 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain SHS2_Rpb7-N PF03876.17 KDO19114.1 - 7.9e-14 51.8 0.5 3.7e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KDO19114.1 - 9.8e-10 38.6 0.2 2.1e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Complex1_LYR PF05347.15 KDO19115.1 - 6e-09 35.8 0.3 7.9e-09 35.4 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) FtsA PF14450.6 KDO19115.1 - 0.019 15.4 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Cell division protein FtsA Complex1_LYR_2 PF13233.6 KDO19115.1 - 0.075 13.8 0.0 0.089 13.5 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Ribosomal_L40e PF01020.17 KDO19116.1 - 7.4e-29 99.4 10.7 8.5e-29 99.2 10.7 1.1 1 0 0 1 1 1 1 Ribosomal L40e family WD40 PF00400.32 KDO19117.1 - 9.4e-47 156.0 22.2 3.5e-08 34.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO19117.1 - 3.2e-09 37.0 1.0 0.16 12.3 0.0 5.0 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KDO19117.1 - 0.0019 16.8 0.1 0.26 9.8 0.1 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KDO19117.1 - 0.0031 16.5 0.1 17 4.2 0.0 4.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO19117.1 - 0.0038 17.1 0.0 0.027 14.4 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KDO19117.1 - 0.013 14.2 7.1 0.26 9.9 0.0 4.1 3 1 1 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KDO19117.1 - 0.058 12.7 0.0 7.3 5.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Cmc1 PF08583.10 KDO19118.1 - 4.7e-14 52.2 1.6 4.7e-14 52.2 1.6 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KDO19118.1 - 0.027 14.7 0.4 0.033 14.4 0.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 KDO19118.1 - 0.099 12.8 0.9 0.21 11.8 0.9 1.7 1 0 0 1 1 1 0 CHCH domain DUF4246 PF14033.6 KDO19119.1 - 3.5e-36 125.3 0.0 5.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ank_4 PF13637.6 KDO19119.1 - 1.3e-28 99.0 4.9 8e-08 32.7 0.2 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19119.1 - 3.7e-27 94.7 6.2 7.9e-08 32.8 0.3 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO19119.1 - 3e-19 68.8 11.2 0.00012 22.3 0.1 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19119.1 - 3.7e-15 54.5 5.6 0.23 12.1 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KDO19119.1 - 3.9e-12 46.0 23.7 0.07 13.6 0.1 7.7 8 1 0 8 8 8 5 Ankyrin repeat CDT1 PF08839.11 KDO19120.1 - 1.4e-11 45.0 0.0 1.6e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor CDT1 like Dynamin_M PF01031.20 KDO19122.1 - 1.6e-07 30.8 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KDO19122.1 - 0.00061 19.9 0.1 0.0025 17.9 0.1 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain Adeno_VII PF03228.14 KDO19122.1 - 0.094 13.4 0.1 2 9.0 0.0 2.4 2 1 1 3 3 3 0 Adenoviral core protein VII Pkinase PF00069.25 KDO19123.1 - 2.8e-68 230.1 0.0 3.9e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19123.1 - 8.3e-37 126.9 0.0 1.4e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO19123.1 - 1.1e-10 41.9 0.4 2.2e-10 41.0 0.4 1.4 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 KDO19123.1 - 8.7e-05 22.0 0.2 0.00023 20.6 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO19123.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KDO19123.1 - 0.0024 18.3 0.8 0.0083 16.5 0.7 2.0 1 1 1 2 2 2 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 KDO19123.1 - 0.0028 16.5 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO19123.1 - 0.014 15.3 0.1 1.1 9.1 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO19123.1 - 0.047 12.7 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PH_8 PF15409.6 KDO19123.1 - 0.12 12.7 0.7 0.5 10.7 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain WD40 PF00400.32 KDO19124.1 - 1.2e-40 136.8 23.3 8e-09 36.0 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO19124.1 - 4.4e-17 62.2 6.6 0.00036 20.8 0.2 6.2 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC_2 PF13696.6 KDO19124.1 - 4.9e-17 61.4 24.8 2.5e-10 40.0 4.2 3.8 3 0 0 3 3 3 2 Zinc knuckle eIF2A PF08662.11 KDO19124.1 - 2e-09 37.6 2.1 0.012 15.5 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A zf-CCHC PF00098.23 KDO19124.1 - 4.6e-05 23.3 11.4 0.00039 20.4 4.1 3.4 3 0 0 3 3 3 2 Zinc knuckle Nucleoporin_N PF08801.11 KDO19124.1 - 0.004 16.0 0.3 2.3 6.9 0.0 2.2 1 1 0 2 2 2 2 Nup133 N terminal like zf-CCHC_3 PF13917.6 KDO19124.1 - 0.0061 16.5 9.0 0.11 12.5 3.8 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 KDO19124.1 - 1.1 9.1 11.4 4 7.2 5.1 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KDO19124.1 - 6.1 6.7 6.1 5.4 6.8 0.6 2.6 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C1 PF00112.23 KDO19127.1 - 2.6e-27 96.4 0.0 3.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO19127.1 - 0.024 13.4 0.4 0.037 12.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase C1-like family DUF4231 PF14015.6 KDO19128.1 - 5.7 7.5 5.9 38 4.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Toprim_2 PF13155.6 KDO19131.1 - 0.031 14.7 0.1 0.035 14.5 0.1 1.1 1 0 0 1 1 1 0 Toprim-like Ligase_CoA PF00549.19 KDO19131.1 - 0.043 13.6 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 CoA-ligase Arf PF00025.21 KDO19132.1 - 3.4e-66 222.0 0.1 3.9e-66 221.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO19132.1 - 2.9e-14 53.0 0.3 1.2e-09 37.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KDO19132.1 - 7.1e-13 48.8 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO19132.1 - 2.9e-12 46.4 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KDO19132.1 - 5.2e-10 39.1 0.0 6.2e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KDO19132.1 - 5.5e-10 39.0 0.0 6.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO19132.1 - 3.9e-07 30.1 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO19132.1 - 0.014 15.9 0.1 0.025 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KDO19132.1 - 0.024 14.2 0.0 0.25 10.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KDO19132.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KDO19132.1 - 0.079 12.5 0.0 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO19132.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.2 2 1 0 2 2 2 0 NACHT domain Vac14_Fig4_bd PF11916.8 KDO19134.1 - 2.3e-72 242.4 11.4 2.3e-72 242.4 11.4 2.6 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KDO19134.1 - 9.1e-48 160.8 0.1 2.4e-41 140.2 0.0 4.5 2 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KDO19134.1 - 1.9e-13 49.4 5.9 5.7e-05 23.0 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 KDO19134.1 - 9.6e-10 38.7 1.6 0.0012 19.0 0.0 4.5 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO19134.1 - 5e-08 33.3 0.1 0.18 12.4 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KDO19134.1 - 4.1e-06 27.1 0.5 2.5 8.5 0.0 5.5 4 3 1 5 5 5 2 HEAT repeats Tti2 PF10521.9 KDO19134.1 - 1.8e-05 24.5 3.0 0.0067 16.0 0.0 3.7 3 1 1 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 KDO19134.1 - 0.031 14.5 2.6 1.1 9.5 0.7 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KDO19134.1 - 0.084 13.2 0.6 1.8 8.9 0.0 3.4 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain RasGEF_N_2 PF14663.6 KDO19134.1 - 0.11 13.0 2.5 4.1 7.8 0.0 3.8 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TIP120 PF08623.10 KDO19134.1 - 0.23 11.2 5.8 1.9 8.2 0.4 3.4 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) Acyl_transf_3 PF01757.22 KDO19135.1 - 6.6e-20 71.4 44.0 6.6e-20 71.4 44.0 1.9 1 1 1 2 2 2 1 Acyltransferase family START PF01852.19 KDO19137.1 - 9.6e-08 31.7 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 START domain Rrp15p PF07890.12 KDO19139.1 - 1.8e-21 76.9 6.0 1.8e-21 76.9 6.0 1.8 2 0 0 2 2 2 1 Rrp15p YL1 PF05764.13 KDO19139.1 - 0.11 12.5 12.6 0.15 12.1 12.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Sox_N PF12444.8 KDO19139.1 - 5.4 8.2 9.9 0.65 11.2 3.8 2.4 3 0 0 3 3 3 0 Sox developmental protein N terminal Acetyltransf_9 PF13527.7 KDO19140.1 - 0.0014 18.8 0.1 0.0066 16.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO19140.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO19140.1 - 0.0017 18.5 0.0 0.0053 17.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO19140.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO19140.1 - 0.13 12.9 0.1 0.42 11.3 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain LTV PF04180.14 KDO19141.1 - 1.6e-28 100.5 24.1 2.6e-18 67.0 14.4 2.6 1 1 1 2 2 2 2 Low temperature viability protein EFhand_Ca_insen PF08726.10 KDO19141.1 - 0.004 17.2 0.5 0.068 13.3 0.3 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand LYRIC PF15686.5 KDO19141.1 - 0.23 11.0 8.1 0.35 10.4 8.1 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Acatn PF13000.7 KDO19143.1 - 0.04 12.4 0.0 0.045 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Ank_5 PF13857.6 KDO19145.1 - 0.00054 20.2 0.2 0.59 10.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO19145.1 - 0.0058 17.2 0.1 0.017 15.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19145.1 - 0.021 15.4 0.1 0.048 14.3 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19146.1 - 3.6e-08 33.8 0.4 1.3e-05 25.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19146.1 - 6.9e-05 23.4 0.1 0.00017 22.1 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO19146.1 - 0.0041 17.4 0.1 0.58 10.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19146.1 - 0.0064 16.9 0.1 1.3 9.8 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat TetR_C_6 PF13977.6 KDO19146.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal DUF5049 PF16468.5 KDO19146.1 - 0.16 11.9 0.0 6.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) IBR PF01485.21 KDO19147.1 - 0.00018 21.6 13.5 0.00018 21.6 13.5 4.6 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain Ank_4 PF13637.6 KDO19148.1 - 0.0026 18.3 0.5 0.23 12.1 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19148.1 - 0.0098 16.2 0.3 7.1 7.1 0.3 3.3 1 1 2 3 3 3 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 KDO19148.1 - 0.022 14.6 0.1 1 9.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5049) Ank_2 PF12796.7 KDO19148.1 - 0.062 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) ADH_zinc_N PF00107.26 KDO19149.1 - 2.8e-15 56.4 0.3 2.8e-15 56.4 0.3 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO19149.1 - 4.8e-11 43.8 0.4 1.4e-10 42.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO19149.1 - 3.9e-09 36.4 0.1 9.7e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EcKinase PF02958.20 KDO19149.1 - 0.018 14.4 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase ATP-synt_G PF04718.15 KDO19150.1 - 0.06 14.2 0.0 0.079 13.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit DnaJ_C PF01556.18 KDO19151.1 - 3.6e-40 137.4 0.3 4.4e-40 137.2 0.3 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KDO19151.1 - 2.5e-15 56.6 18.7 5.3e-15 55.5 18.7 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KDO19151.1 - 0.013 15.6 5.3 2 8.5 1.5 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 KDO19151.1 - 0.18 11.9 0.4 0.41 10.7 0.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Anti-TRAP PF15777.5 KDO19151.1 - 0.34 10.9 11.1 1.2 9.1 0.9 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KDO19151.1 - 1 9.5 7.2 2.1 8.5 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 KDO19151.1 - 3.8 7.7 8.3 0.39 10.9 1.4 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 Ank_4 PF13637.6 KDO19154.1 - 0.014 16.0 0.6 7.1 7.3 0.0 3.3 2 1 2 4 4 4 0 Ankyrin repeats (many copies) ABC2_membrane PF01061.24 KDO19155.1 - 9.9e-64 214.6 59.5 2.4e-34 118.6 30.0 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO19155.1 - 1e-33 116.7 0.0 1.1e-17 64.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO19155.1 - 8.5e-06 25.8 0.0 0.47 10.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO19155.1 - 2e-05 24.6 0.0 0.00078 19.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KDO19155.1 - 4e-05 23.3 1.2 0.0075 16.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO19155.1 - 5.5e-05 22.8 0.3 0.22 11.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KDO19155.1 - 0.00012 22.5 0.0 0.27 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KDO19155.1 - 0.00054 20.2 0.2 0.97 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KDO19155.1 - 0.001 19.2 0.1 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO19155.1 - 0.0021 18.5 1.1 0.18 12.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KDO19155.1 - 0.0022 18.0 0.1 0.85 9.6 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KDO19155.1 - 0.0052 16.5 1.3 2.1 8.0 0.5 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KDO19155.1 - 0.013 16.1 0.3 0.62 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KDO19155.1 - 0.019 14.1 47.5 0.012 14.8 17.0 2.6 3 0 0 3 3 2 0 ABC-2 family transporter protein SMC_N PF02463.19 KDO19155.1 - 0.021 14.3 0.3 16 4.8 0.0 3.7 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KDO19155.1 - 0.021 15.3 0.1 6.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KDO19155.1 - 0.035 13.4 0.1 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 KDO19155.1 - 0.059 13.8 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 KDO19155.1 - 0.081 12.8 2.2 0.6 10.0 0.0 2.8 3 0 0 3 3 3 0 NTPase cobW PF02492.19 KDO19155.1 - 0.088 12.4 2.3 5.6 6.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KDO19155.1 - 0.089 13.1 1.2 1 9.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO19155.1 - 0.11 12.2 3.3 3.4 7.3 0.5 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO19155.1 - 0.14 11.4 0.9 7.9 5.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin MCM PF00493.23 KDO19155.1 - 0.15 11.2 0.2 0.5 9.4 0.1 1.8 2 0 0 2 2 2 0 MCM P-loop domain NACHT PF05729.12 KDO19155.1 - 0.16 11.9 2.4 8.5 6.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 KDO19155.1 - 0.27 10.7 0.9 14 5.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 KDO19155.1 - 4.1 7.4 4.9 27 4.8 0.8 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Dicer_N PF17895.1 KDO19156.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain Wzy_C PF04932.15 KDO19157.1 - 0.018 14.7 5.8 1.4 8.5 0.3 2.7 2 0 0 2 2 2 0 O-Antigen ligase BT1 PF03092.16 KDO19158.1 - 1.3e-10 40.1 1.4 1.3e-10 40.1 1.4 3.1 2 1 1 3 3 3 2 BT1 family PUCC PF03209.15 KDO19158.1 - 0.0011 18.1 5.2 0.013 14.6 0.4 2.8 2 0 0 2 2 2 2 PUCC protein E1-E2_ATPase PF00122.20 KDO19158.1 - 2 7.9 7.7 0.23 10.9 0.3 2.9 3 0 0 3 3 3 0 E1-E2 ATPase Cupin_4 PF08007.12 KDO19159.1 - 1.8e-12 47.3 0.1 2.6e-11 43.6 0.1 2.2 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KDO19159.1 - 8.1e-10 38.8 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KDO19159.1 - 0.00039 20.1 0.0 0.017 14.9 0.0 3.1 4 0 0 4 4 4 1 Cupin domain JmjC PF02373.22 KDO19159.1 - 0.0063 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Elicitin PF00964.17 KDO19160.1 - 0.0022 18.0 4.0 0.0022 18.0 4.0 2.3 2 0 0 2 2 2 2 Elicitin zinc_ribbon_11 PF11682.8 KDO19162.1 - 0.0021 18.0 0.1 0.0037 17.3 0.1 1.3 1 0 0 1 1 1 1 Probable zinc-ribbon Elicitin PF00964.17 KDO19166.1 - 0.00013 22.0 3.1 0.00013 22.0 3.1 3.5 3 1 0 3 3 3 2 Elicitin RED_N PF07808.13 KDO19167.1 - 0.0021 17.7 0.8 0.0021 17.7 0.8 2.1 1 1 1 2 2 2 1 RED-like protein N-terminal region Gpi16 PF04113.14 KDO19168.1 - 1.2e-13 50.5 0.1 1.5e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component SPRY PF00622.28 KDO19170.1 - 1.4e-07 31.7 0.0 4.3e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 SPRY domain ATP-grasp_5 PF13549.6 KDO19170.1 - 0.0065 15.9 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Neuralized PF07177.12 KDO19170.1 - 0.032 14.3 0.0 0.053 13.5 0.0 1.3 1 1 0 1 1 1 0 Neuralized SPRY PF00622.28 KDO19171.1 - 7.8e-06 26.0 0.0 1.5e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 SPRY domain ketoacyl-synt PF00109.26 KDO19172.1 - 3.7e-59 200.3 0.7 5.4e-59 199.8 0.7 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KDO19172.1 - 2.6e-37 127.4 0.6 6.5e-36 122.9 0.7 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KDO19172.1 - 0.00041 19.8 0.2 0.00071 19.0 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain NMD3 PF04981.13 KDO19173.1 - 7.5e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NMD3 family PQ-loop PF04193.14 KDO19174.1 - 4.5e-09 35.9 2.2 8.9e-09 35.0 2.2 1.5 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 KDO19174.1 - 0.0016 18.4 3.5 0.003 17.5 3.5 1.4 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange IFT20 PF14931.6 KDO19178.1 - 1.8e-38 131.4 14.1 2e-38 131.2 14.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 CSN7a_helixI PF18392.1 KDO19178.1 - 0.0068 16.3 0.5 0.013 15.3 0.4 1.6 1 1 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Arm_2 PF04826.13 KDO19179.1 - 3.3e-06 26.8 0.0 0.00031 20.3 0.1 2.7 2 1 1 3 3 3 2 Armadillo-like DUF4880 PF16220.5 KDO19179.1 - 0.12 12.3 3.3 0.4 10.6 3.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) PDZ_6 PF17820.1 KDO19180.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO19180.1 - 1.5e-05 25.3 0.0 2.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Methyltransf_15 PF09445.10 KDO19181.1 - 4.8e-35 120.6 0.0 6.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KDO19181.1 - 5.5e-07 29.5 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KDO19181.1 - 2.2e-06 28.2 0.0 5.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO19181.1 - 1.9e-05 24.4 0.0 5.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 KDO19181.1 - 8.2e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KDO19181.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KDO19181.1 - 0.0014 19.3 0.0 0.0051 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.8 KDO19181.1 - 0.02 14.1 0.4 0.075 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) Methyltransf_18 PF12847.7 KDO19181.1 - 0.034 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KDO19181.1 - 0.052 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) KIX_2 PF16987.5 KDO19182.1 - 0.00035 20.5 0.0 0.00035 20.5 0.0 2.3 3 0 0 3 3 3 1 KIX domain Macoilin PF09726.9 KDO19182.1 - 9.1 4.7 14.2 17 3.8 14.2 1.5 1 0 0 1 1 1 0 Macoilin family UQ_con PF00179.26 KDO19183.1 - 1.2e-42 144.9 0.0 1.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KDO19183.1 - 0.21 11.8 0.0 0.74 10.1 0.0 1.8 2 0 0 2 2 2 0 RWD domain B56 PF01603.20 KDO19184.1 - 2.5e-18 66.2 0.0 1.5e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) PAM2 PF07145.15 KDO19184.1 - 0.13 12.0 1.4 0.33 10.7 1.4 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Metal_resist PF13801.6 KDO19184.1 - 1.4 9.1 7.4 0.14 12.3 0.6 2.4 2 0 0 2 2 2 0 Heavy-metal resistance SUZ PF12752.7 KDO19184.1 - 6.5 7.6 7.7 0.92 10.3 0.3 2.9 2 1 0 2 2 2 0 SUZ domain Synaptobrevin PF00957.21 KDO19185.1 - 4.9e-31 106.4 0.5 8.5e-31 105.6 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KDO19185.1 - 2e-24 85.4 0.1 3.6e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Orbi_VP3 PF01700.16 KDO19185.1 - 9.7e-05 20.5 0.2 0.00013 20.0 0.2 1.2 1 0 0 1 1 1 1 Orbivirus VP3 (T2) protein DUF1765 PF08578.10 KDO19186.1 - 8.5e-09 35.9 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) CH PF00307.31 KDO19187.1 - 1.5e-13 50.9 0.1 0.00019 21.6 0.0 4.9 5 0 0 5 5 5 4 Calponin homology (CH) domain MFS_1 PF07690.16 KDO19189.1 - 0.00087 18.3 5.6 0.001 18.1 5.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KDO19190.1 - 4.1e-13 49.0 36.6 4.1e-13 49.0 36.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KDO19191.1 - 1.7e-11 43.7 17.9 3.3e-11 42.7 17.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Anophelin PF10731.9 KDO19191.1 - 5 7.0 5.0 1.1 9.1 0.3 2.4 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito MFS_1 PF07690.16 KDO19192.1 - 1.2e-15 57.3 26.7 1.2e-15 57.3 26.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3464 PF11947.8 KDO19192.1 - 0.26 11.0 0.5 0.65 9.7 0.5 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 KDO19194.1 - 2.6e-11 43.0 31.3 2.2e-09 36.7 16.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO19194.1 - 0.0069 15.3 2.4 0.0069 15.3 2.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter BRI3BP PF14965.6 KDO19194.1 - 0.06 12.9 3.8 1.5 8.3 1.4 3.0 2 1 0 2 2 2 0 Negative regulator of p53/TP53 SpdB PF05122.13 KDO19195.1 - 0.082 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Mobile element transfer protein Ank_4 PF13637.6 KDO19196.1 - 5.5e-19 68.3 4.3 2.8e-14 53.3 0.9 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19196.1 - 3.6e-16 59.5 0.8 2.9e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO19196.1 - 1.8e-13 50.2 5.3 7.9e-07 29.2 0.2 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO19196.1 - 8e-13 48.3 1.8 8.8e-09 35.5 0.3 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19196.1 - 3.1e-11 42.4 2.7 8.6e-05 22.7 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat SNF2_N PF00176.23 KDO19197.1 - 3.9e-62 210.0 0.0 8e-62 209.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO19197.1 - 4.1e-08 33.5 0.0 8.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KDO19197.1 - 2.8e-07 30.3 4.2 5.3e-07 29.4 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KDO19197.1 - 5.3e-05 23.0 7.2 0.00011 22.0 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO19197.1 - 0.00052 19.8 8.4 0.001 18.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO19197.1 - 0.00064 19.7 4.2 0.00095 19.1 3.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO19197.1 - 0.0011 18.9 8.4 0.0021 18.0 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 KDO19197.1 - 0.004 17.2 0.0 0.014 15.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KDO19197.1 - 0.0045 17.3 8.4 0.01 16.1 8.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_14 PF17978.1 KDO19197.1 - 0.012 16.1 3.0 0.03 14.7 3.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ERCC3_RAD25_C PF16203.5 KDO19197.1 - 0.012 14.8 0.0 0.044 13.0 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase F-box-like PF12937.7 KDO19197.1 - 0.028 14.3 0.2 0.07 13.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KDO19197.1 - 0.031 14.2 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain zf-C3HC4_2 PF13923.6 KDO19197.1 - 0.2 11.5 6.4 0.54 10.2 6.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO19197.1 - 0.33 11.2 6.6 1.2 9.4 6.6 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KDO19197.1 - 0.49 10.3 1.8 0.88 9.5 1.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 KDO19197.1 - 0.72 9.8 4.3 2 8.4 4.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KDO19197.1 - 6.5 6.6 6.9 12 5.8 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DIT1_PvcA PF05141.12 KDO19199.1 - 5.4e-78 262.2 0.0 4.9e-77 259.1 0.0 2.1 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KDO19199.1 - 4.2e-28 98.9 0.3 7e-28 98.2 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2358 PF10184.9 KDO19199.1 - 0.06 13.6 0.2 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) DUF5570 PF17731.1 KDO19200.1 - 0.17 12.0 2.0 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5570) Ank_2 PF12796.7 KDO19201.1 - 2.5e-65 217.0 5.1 3.3e-17 62.8 0.0 4.7 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KDO19201.1 - 1.5e-41 139.1 8.8 9.6e-07 29.0 0.0 8.1 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KDO19201.1 - 9.3e-40 134.5 13.8 1.3e-11 44.8 0.1 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19201.1 - 1.2e-34 117.9 13.6 4.5e-13 49.2 0.2 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19201.1 - 1e-30 102.3 3.7 0.0012 19.1 0.0 7.7 8 1 1 9 9 9 6 Ankyrin repeat DUF5570 PF17731.1 KDO19202.1 - 0.16 12.0 1.1 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5570) DUF2722 PF10846.8 KDO19202.1 - 0.99 8.3 2.1 0.67 8.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TauD PF02668.16 KDO19203.1 - 1.5e-17 64.3 0.6 1.7e-17 64.1 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ank_2 PF12796.7 KDO19204.1 - 7e-07 29.8 0.5 0.27 11.8 0.1 4.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19204.1 - 0.00092 19.7 3.1 14 6.4 0.1 6.2 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19204.1 - 0.0025 18.1 9.0 11 6.5 0.0 6.9 6 3 3 9 9 9 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19204.1 - 0.079 13.6 5.7 1.7e+02 3.4 0.0 6.9 9 0 0 9 9 9 0 Ankyrin repeat PMSR PF01625.21 KDO19205.1 - 9.8e-61 204.4 0.8 1.2e-60 204.2 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ank_2 PF12796.7 KDO19206.1 - 3e-16 59.8 0.9 3.2e-07 30.8 0.1 4.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19206.1 - 4.4e-10 39.9 10.2 0.0046 17.5 0.5 6.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19206.1 - 2.8e-09 37.0 12.7 2.3 8.6 0.2 7.1 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19206.1 - 1.8e-05 24.8 10.3 35 5.4 0.1 7.2 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 KDO19206.1 - 1.2 9.7 6.5 1.1e+02 3.5 0.0 4.5 3 2 0 3 3 3 0 Ankyrin repeat Mannosyl_trans3 PF11051.8 KDO19207.1 - 4.9e-33 114.7 0.0 7.1e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 KDO19208.1 - 1.2e-33 116.7 0.0 1.6e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Peptidase_S28 PF05577.12 KDO19209.1 - 1.4e-93 314.1 1.0 1.6e-93 313.9 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO19209.1 - 0.0003 19.6 0.0 0.00057 18.7 0.0 1.5 1 1 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KDO19209.1 - 0.00099 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family EamA PF00892.20 KDO19210.1 - 1.3e-19 70.7 36.9 4.1e-11 43.2 16.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KDO19210.1 - 2.2e-08 34.0 14.7 5.1e-08 32.8 14.7 1.8 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KDO19210.1 - 2.8e-05 23.5 11.0 2.8e-05 23.5 11.0 2.7 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KDO19210.1 - 0.00039 19.9 12.6 0.00045 19.7 11.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family Sugar_transport PF06800.12 KDO19210.1 - 0.0036 16.7 2.0 0.0036 16.7 2.0 3.9 2 1 2 4 4 4 2 Sugar transport protein DUF3955 PF13127.6 KDO19210.1 - 0.025 14.4 1.5 0.025 14.4 1.5 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3955) Phage_holin_3_2 PF04550.12 KDO19210.1 - 0.61 10.7 3.3 0.75 10.4 0.1 2.7 3 0 0 3 3 3 0 Phage holin family 2 Chordopox_A13L PF05961.11 KDO19210.1 - 5.9 7.2 7.8 15 5.9 0.1 2.9 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Multi_Drug_Res PF00893.19 KDO19210.1 - 7 7.4 11.8 0.19 12.4 1.8 3.1 3 1 0 3 3 3 0 Small Multidrug Resistance protein Peptidase_S28 PF05577.12 KDO19211.1 - 2.7e-91 306.5 1.2 3.1e-91 306.3 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO19211.1 - 0.0001 21.1 1.5 0.00013 20.8 0.0 1.9 2 1 1 3 3 3 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KDO19211.1 - 0.00032 20.2 0.1 0.00072 19.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KDO19211.1 - 0.0035 17.0 1.3 0.066 12.8 0.1 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KDO19212.1 - 2.8e-33 115.4 0.0 3.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 KDO19213.1 - 1.6e-98 330.4 2.0 2e-98 330.0 2.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO19213.1 - 4.5e-05 22.3 0.1 9.1e-05 21.3 0.1 1.5 2 0 0 2 2 2 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KDO19213.1 - 0.00048 19.7 0.0 0.00091 18.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family OPT PF03169.15 KDO19214.1 - 3.9e-82 276.8 45.7 9.7e-52 176.4 21.8 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Thr_synth_N PF14821.6 KDO19216.1 - 3e-29 101.1 0.0 6.3e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KDO19216.1 - 6.1e-20 71.8 0.0 6.7e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DnaJ PF00226.31 KDO19219.1 - 5.1e-18 65.0 1.5 7.6e-18 64.4 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_66 PF13199.6 KDO19219.1 - 0.027 13.2 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 LRR_4 PF12799.7 KDO19220.1 - 5.8e-09 36.1 1.0 0.00072 19.9 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19220.1 - 1.5e-07 31.1 1.5 0.0013 18.5 0.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KDO19220.1 - 0.013 15.9 4.1 1.3 9.8 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2267 PF10025.9 KDO19220.1 - 0.047 14.0 0.1 0.6 10.4 0.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Crystall PF00030.19 KDO19221.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Defb50 PF17546.2 KDO19221.1 - 0.75 9.7 5.1 47 4.0 0.1 3.6 3 0 0 3 3 3 0 Beta defensin 50 DPPIV_N PF00930.21 KDO19223.1 - 3.6e-68 229.9 0.0 1.6e-66 224.5 0.0 2.0 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KDO19223.1 - 2.1e-46 158.1 0.2 3e-46 157.6 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KDO19223.1 - 2e-10 40.7 3.7 3e-09 36.9 2.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 KDO19223.1 - 0.045 13.7 0.3 6.7 6.8 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DLH PF01738.18 KDO19223.1 - 0.051 13.1 0.8 0.61 9.6 0.8 2.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KDO19223.1 - 0.087 12.1 0.9 0.4 9.9 0.8 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF5043 PF16446.5 KDO19224.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) Methyltransf_7 PF03492.15 KDO19226.1 - 1.5e-41 142.8 0.0 1.9e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase START PF01852.19 KDO19227.1 - 0.00039 19.9 0.0 0.0006 19.3 0.0 1.2 1 0 0 1 1 1 1 START domain Mannosyl_trans3 PF11051.8 KDO19228.1 - 6.9e-36 124.0 0.0 2.4e-24 86.2 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative zf-C3HC4_3 PF13920.6 KDO19228.1 - 6.5e-13 48.3 10.3 1.4e-12 47.3 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KDO19228.1 - 3.2e-10 40.0 0.2 8.3e-10 38.7 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO19228.1 - 6.3e-08 33.0 0.2 2.9e-07 30.9 0.2 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19228.1 - 5.8e-07 30.0 0.0 1.9e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-RING_2 PF13639.6 KDO19228.1 - 5.2e-06 26.7 11.1 1.7e-05 25.0 11.1 2.0 1 0 0 1 1 1 1 Ring finger domain Ank PF00023.30 KDO19228.1 - 5.5e-06 26.6 0.4 2.5e-05 24.5 0.1 2.4 2 0 0 2 2 1 1 Ankyrin repeat Ank_3 PF13606.6 KDO19228.1 - 2.9e-05 24.1 0.0 0.00015 21.9 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat Prok-RING_4 PF14447.6 KDO19228.1 - 0.0043 16.9 11.0 0.0092 15.8 11.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO19228.1 - 0.0078 16.2 10.4 0.019 14.9 10.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain PH PF00169.29 KDO19228.1 - 0.022 15.3 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 PH domain zf-C3HC4_2 PF13923.6 KDO19228.1 - 0.041 13.7 15.6 0.021 14.7 13.0 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KDO19228.1 - 1.4 8.8 7.5 3.6 7.4 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KDO19228.1 - 1.6 8.4 7.2 3.6 7.3 7.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 KDO19228.1 - 8.4 6.7 12.8 28 5.0 12.8 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KDO19232.1 - 4e-05 23.7 17.0 0.0001 22.4 17.0 1.6 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO19232.1 - 0.0032 17.7 6.2 0.0071 16.5 6.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3074 PF11274.8 KDO19232.1 - 0.0078 16.2 0.0 0.19 11.7 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3074) FpoO PF10621.9 KDO19232.1 - 0.27 11.5 4.7 0.52 10.6 4.7 1.4 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Siva PF05458.12 KDO19232.1 - 0.86 9.3 8.5 1.7 8.3 8.5 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-C3HC4 PF00097.25 KDO19232.1 - 4.2 7.3 12.1 1.1e+02 2.8 13.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sugarporin_N PF11471.8 KDO19236.1 - 0.067 13.2 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Nnf1 PF03980.14 KDO19236.1 - 0.072 13.5 0.2 7 7.1 0.1 2.2 2 0 0 2 2 2 0 Nnf1 WW PF00397.26 KDO19238.1 - 0.074 13.2 0.4 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 WW domain Pkinase PF00069.25 KDO19239.1 - 1.1e-49 169.2 0.0 1.4e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19239.1 - 1.1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO19239.1 - 2.2e-06 26.9 0.0 2.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO19239.1 - 1.5e-05 24.0 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO19239.1 - 4.1e-05 23.0 0.4 5.7e-05 22.6 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO19239.1 - 4.2e-05 23.6 4.1 0.012 15.5 1.4 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO19239.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KDO19239.1 - 0.061 12.9 0.0 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KDO19239.1 - 0.098 12.2 0.1 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase LRR_6 PF13516.6 KDO19240.1 - 2.4e-08 33.4 1.4 0.016 15.2 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KDO19240.1 - 0.005 17.2 6.9 0.47 10.9 0.1 5.5 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO19240.1 - 0.024 14.1 1.6 0.55 9.7 0.5 2.7 2 1 1 3 3 3 0 Leucine-rich repeat LRR_8 PF13855.6 KDO19240.1 - 0.029 14.1 8.7 1.9 8.3 0.1 4.9 4 1 1 5 5 5 0 Leucine rich repeat DUF2889 PF11136.8 KDO19240.1 - 0.15 12.3 0.2 0.38 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) UBM PF14377.6 KDO19240.1 - 0.4 10.2 4.1 0.13 11.7 0.5 2.1 2 0 0 2 2 2 0 Ubiquitin binding region LRR_6 PF13516.6 KDO19242.1 - 3.3e-09 36.0 4.4 0.00028 20.7 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 KDO19242.1 - 0.00033 21.0 2.9 3.3 8.3 0.2 5.0 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19242.1 - 0.034 13.9 6.0 1.5 8.6 0.5 4.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 KDO19243.1 - 3.1e-06 26.8 8.3 0.65 10.2 0.0 5.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KDO19243.1 - 0.0015 18.9 0.3 1.1 9.8 0.0 4.1 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19243.1 - 0.002 17.8 1.1 0.98 9.2 0.0 4.3 3 1 0 3 3 3 1 Leucine rich repeat DOMON PF03351.17 KDO19244.1 - 7.2e-23 81.2 0.0 1.6e-08 34.8 0.0 3.3 3 0 0 3 3 3 3 DOMON domain Ferric_reduct PF01794.19 KDO19244.1 - 8.9e-13 48.5 12.8 8.9e-13 48.5 12.8 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO19244.1 - 5.3e-11 42.9 0.0 3.2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO19244.1 - 4e-05 23.7 0.0 9.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KDO19244.1 - 0.00011 22.7 0.0 0.00043 20.9 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Pkinase_Tyr PF07714.17 KDO19245.1 - 2.1e-50 171.4 0.0 2.6e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19245.1 - 1.2e-46 159.2 0.0 1.7e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 KDO19245.1 - 3.1e-08 33.8 0.0 6.5e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 C2 domain RIO1 PF01163.22 KDO19245.1 - 0.0022 17.7 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KDO19245.1 - 0.0022 16.8 0.1 0.0034 16.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO19245.1 - 0.0045 16.0 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO19245.1 - 0.026 13.9 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO19245.1 - 0.027 14.4 0.3 1.3 8.9 0.3 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO19245.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KDO19246.1 - 3.1e-36 125.0 0.0 4.3e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19246.1 - 2.7e-35 122.0 0.0 4.1e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 KDO19246.1 - 4.8e-09 36.4 0.0 8.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kdo PF06293.14 KDO19246.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family B9-C2 PF07162.11 KDO19246.1 - 0.019 15.2 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary basal body-associated, B9 protein Kinase-like PF14531.6 KDO19246.1 - 0.05 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO19246.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.23 KDO19247.1 - 0.00016 21.7 0.1 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GBP PF02263.19 KDO19247.1 - 0.00067 19.0 0.0 0.0021 17.4 0.0 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KDO19247.1 - 0.0026 17.8 0.2 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 Dynamin family RHD3 PF05879.12 KDO19247.1 - 0.0038 15.5 0.5 0.0082 14.3 0.0 1.8 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) Pkinase_Tyr PF07714.17 KDO19248.1 - 2.8e-85 285.7 0.0 4.7e-52 176.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO19248.1 - 4.6e-77 259.0 0.0 8.3e-48 163.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain C2 PF00168.30 KDO19248.1 - 5.6e-08 33.0 0.1 1.1e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KDO19248.1 - 2.1e-06 27.3 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO19248.1 - 0.00033 19.5 0.0 0.00086 18.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KDO19248.1 - 0.00054 20.0 0.5 0.78 9.6 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO19248.1 - 0.0015 18.2 0.2 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KDO19248.1 - 0.002 17.5 0.2 0.52 9.6 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO19248.1 - 0.18 10.8 0.5 1 8.3 0.0 2.3 3 0 0 3 3 3 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 KDO19251.1 - 3.7e-36 124.7 0.0 2.3e-25 89.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO19251.1 - 1.5e-29 103.2 0.0 1.3e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KDO19251.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO19251.1 - 0.031 13.6 0.1 0.061 12.7 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acylphosphatase PF00708.18 KDO19254.1 - 1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Methyltransf_15 PF09445.10 KDO19255.1 - 1.4e-16 60.5 0.1 2e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Nup35_RRM PF05172.13 KDO19255.1 - 0.017 15.1 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Methyltr_RsmB-F PF01189.17 KDO19255.1 - 0.035 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FYVE PF01363.21 KDO19256.1 - 2e-14 53.4 12.7 2e-14 53.4 12.7 1.7 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO19256.1 - 0.14 12.4 5.9 0.3 11.3 5.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C4_ClpX PF06689.13 KDO19256.1 - 0.54 10.2 3.1 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-RING_5 PF14634.6 KDO19256.1 - 0.94 9.5 10.0 3 7.9 10.0 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Siva PF05458.12 KDO19256.1 - 1.5 8.5 6.1 2.9 7.5 6.1 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_2 PF13639.6 KDO19256.1 - 2 8.8 9.4 5.3 7.5 9.4 1.8 1 0 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 KDO19256.1 - 2.1 8.7 11.1 0.22 11.9 6.3 1.8 2 0 0 2 2 2 0 C1 domain Codanin-1_C PF15296.6 KDO19257.1 - 7.6e-05 22.8 0.0 0.00063 19.8 0.0 2.6 2 0 0 2 2 2 1 Codanin-1 C-terminus AAA_2 PF07724.14 KDO19258.1 - 3.7e-52 176.9 0.0 1.7e-49 168.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KDO19258.1 - 1.9e-32 111.3 5.5 1.9e-32 111.3 5.5 2.4 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KDO19258.1 - 2.9e-25 88.1 1.5 8.6e-25 86.6 0.0 2.8 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KDO19258.1 - 5.5e-22 78.6 0.0 1.7e-12 47.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KDO19258.1 - 2e-16 60.2 0.0 1.5e-10 41.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO19258.1 - 4.7e-10 39.9 3.4 0.002 18.4 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KDO19258.1 - 7.1e-09 36.3 7.5 3.3e-05 24.3 0.1 4.7 4 1 0 4 4 4 2 AAA ATPase domain AAA_7 PF12775.7 KDO19258.1 - 1.1e-06 28.3 0.0 0.037 13.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 KDO19258.1 - 1.7e-06 27.8 0.1 0.047 13.4 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 KDO19258.1 - 2.9e-06 26.8 0.1 0.092 12.1 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KDO19258.1 - 3.7e-06 26.8 0.0 0.023 14.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KDO19258.1 - 2.9e-05 24.1 0.1 1.8 8.4 0.0 4.1 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KDO19258.1 - 5.1e-05 23.8 1.2 0.66 10.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KDO19258.1 - 8.3e-05 22.3 0.7 1 8.9 0.0 4.4 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 KDO19258.1 - 0.00011 22.6 0.0 0.69 10.3 0.0 3.1 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.12 KDO19258.1 - 0.00011 22.1 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 KDO19258.1 - 0.00024 21.1 0.1 1.1 9.2 0.0 2.8 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KDO19258.1 - 0.00032 20.5 1.4 0.87 9.3 0.7 3.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KDO19258.1 - 0.00056 20.1 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KDO19258.1 - 0.00076 19.5 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO19258.1 - 0.0014 18.6 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KDO19258.1 - 0.0015 18.3 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KDO19258.1 - 0.0022 18.4 0.3 1.5 9.1 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KDO19258.1 - 0.0025 18.3 10.0 0.055 14.0 0.0 3.3 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KDO19258.1 - 0.0031 17.7 0.0 5.2 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KDO19258.1 - 0.01 15.1 0.9 0.89 8.7 0.0 3.1 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_28 PF13521.6 KDO19258.1 - 0.013 15.7 6.4 2.8 8.2 0.0 4.3 4 1 1 5 5 4 0 AAA domain ABC_tran PF00005.27 KDO19258.1 - 0.014 16.0 0.6 5.3 7.6 0.0 3.2 3 1 0 3 3 3 0 ABC transporter T2SSE PF00437.20 KDO19258.1 - 0.018 14.1 0.2 0.11 11.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 KDO19258.1 - 0.043 13.6 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 KDO19258.1 - 0.06 13.2 0.0 20 5.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KDO19258.1 - 0.06 13.0 0.4 22 4.6 0.0 3.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DivIC PF04977.15 KDO19258.1 - 0.1 12.3 3.2 0.26 11.1 3.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Nop16 PF09420.10 KDO19258.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.2 2 1 0 2 2 1 0 Ribosome biogenesis protein Nop16 KTI12 PF08433.10 KDO19258.1 - 0.11 11.9 0.6 1.3 8.4 0.0 2.6 3 0 0 3 3 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 KDO19258.1 - 0.13 12.2 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 NTPase DNA_pol3_delta2 PF13177.6 KDO19258.1 - 0.14 11.9 0.0 32 4.2 0.0 3.4 4 0 0 4 4 3 0 DNA polymerase III, delta subunit PduV-EutP PF10662.9 KDO19258.1 - 0.16 11.7 0.0 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation betaPIX_CC PF16523.5 KDO19258.1 - 0.67 9.8 4.7 2.6 7.9 4.7 2.0 2 0 0 2 2 1 0 betaPIX coiled coil Spc7 PF08317.11 KDO19258.1 - 2.4 7.0 9.2 3.9 6.3 9.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_11 PF13086.6 KDO19258.1 - 2.7 7.7 7.3 66 3.2 6.7 2.8 2 1 0 2 2 2 0 AAA domain APG6_N PF17675.1 KDO19258.1 - 5.7 7.5 12.6 11 6.5 12.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_17 PF13207.6 KDO19258.1 - 6.1 7.3 8.7 66 3.9 0.1 3.6 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 KDO19259.1 - 1.5e-66 224.5 0.0 1.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19259.1 - 1.6e-44 152.1 0.0 2.1e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19259.1 - 3e-07 30.1 0.1 1.1e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO19259.1 - 3.9e-06 25.9 0.0 5.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO19259.1 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO19259.1 - 0.053 13.4 0.0 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19259.1 - 0.11 11.4 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain GMP_PDE_delta PF05351.11 KDO19260.1 - 9.3e-61 204.5 0.3 1.3e-60 204.0 0.3 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit DUF5592 PF17332.2 KDO19261.1 - 0.36 11.4 0.1 0.36 11.4 0.1 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5592) SURF6 PF04935.12 KDO19263.1 - 2.5e-24 86.2 42.9 2.5e-24 86.2 42.9 2.4 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KDO19263.1 - 2e-06 28.3 0.8 2e-06 28.3 0.8 6.8 4 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 G-gamma PF00631.22 KDO19264.1 - 4.7e-12 45.7 0.0 5.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain Paralemmin PF03285.15 KDO19264.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 Paralemmin ABC_tran_CTD PF16326.5 KDO19264.1 - 0.019 15.2 0.2 0.024 14.9 0.2 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain LPP PF04728.13 KDO19264.1 - 0.048 14.0 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Pkinase PF00069.25 KDO19265.1 - 2.3e-47 161.6 0.0 4.1e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19265.1 - 1.5e-31 109.7 0.0 2.1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KDO19265.1 - 8.5e-08 31.9 1.9 1.4e-05 24.6 1.9 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 KDO19265.1 - 2.1e-05 24.5 2.4 0.1 12.7 0.9 2.7 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain APH PF01636.23 KDO19265.1 - 0.00039 20.4 0.4 0.00095 19.1 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO19265.1 - 0.0033 16.3 0.0 0.0078 15.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO19265.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PUF PF00806.19 KDO19266.1 - 0.025 14.3 0.3 0.071 12.8 0.1 1.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat FTCD_N PF07837.12 KDO19267.1 - 0.12 12.2 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain GTP_EFTU PF00009.27 KDO19269.1 - 4.8e-64 215.5 0.0 7.6e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KDO19269.1 - 1.2e-26 92.6 0.1 2.7e-26 91.4 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KDO19269.1 - 1.6e-21 76.1 0.0 4.7e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 KDO19269.1 - 5.2e-14 52.1 0.0 1.2e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 KDO19269.1 - 6.1e-09 35.8 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KDO19269.1 - 1.5e-07 31.7 0.0 3.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO19269.1 - 0.0023 18.0 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nramp PF01566.18 KDO19270.1 - 1.6e-104 349.7 25.7 2e-104 349.4 25.7 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Pkinase_Tyr PF07714.17 KDO19271.1 - 1.4e-45 155.6 0.0 1.9e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19271.1 - 5.8e-45 153.7 0.0 8e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 KDO19271.1 - 0.00024 21.4 9.0 0.023 15.1 0.0 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO19271.1 - 0.05 14.1 0.1 9.5 7.2 0.1 3.6 2 1 0 2 2 2 0 Leucine Rich Repeat PsbX PF06596.11 KDO19271.1 - 1.7 8.7 8.2 1.4 9.0 5.7 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) LRR_8 PF13855.6 KDO19271.1 - 4.2 7.2 6.1 2.5 7.9 0.7 3.2 2 1 1 3 3 3 0 Leucine rich repeat PsbX PF06596.11 KDO19272.1 - 0.35 10.9 6.8 0.83 9.7 6.8 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) WASH-7_mid PF14744.6 KDO19274.1 - 2.5e-140 467.5 3.2 2.5e-140 467.5 3.2 2.0 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_N PF14745.6 KDO19274.1 - 1.6e-101 340.6 0.0 3.8e-72 243.6 0.0 2.2 1 1 1 2 2 2 2 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 KDO19274.1 - 2.4e-59 200.0 5.0 5.6e-59 198.8 5.0 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal zf-RING_2 PF13639.6 KDO19275.1 - 2.8e-12 46.7 9.9 7e-12 45.5 9.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO19275.1 - 3.9e-09 36.2 9.9 8.1e-09 35.2 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO19275.1 - 5.2e-07 29.3 5.2 1.3e-06 28.1 5.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO19275.1 - 5.5e-07 29.3 7.5 1.2e-06 28.2 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO19275.1 - 7.9e-07 29.1 0.5 6.2e-06 26.2 0.3 1.9 2 0 0 2 2 2 1 PX domain zf-RING_UBOX PF13445.6 KDO19275.1 - 8.9e-07 28.8 2.9 8.9e-07 28.8 2.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO19275.1 - 3e-06 27.0 8.9 5.1e-06 26.2 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO19275.1 - 1.4e-05 25.3 11.8 1.4e-05 25.3 11.8 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO19275.1 - 0.0002 21.2 8.7 0.00042 20.2 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KDO19275.1 - 0.00065 19.5 3.5 0.002 17.9 2.7 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KDO19275.1 - 0.0015 18.6 10.1 0.007 16.4 10.1 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KDO19275.1 - 0.025 14.8 6.1 0.052 13.8 6.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 KDO19275.1 - 0.077 12.9 10.9 0.15 11.9 10.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GAF_3 PF13492.6 KDO19275.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 GAF domain Zn_ribbon_17 PF17120.5 KDO19275.1 - 0.17 11.5 9.5 0.34 10.6 9.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KDO19275.1 - 0.22 11.6 7.7 0.66 10.1 7.7 1.9 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 KDO19275.1 - 0.84 9.8 6.9 2.1 8.6 6.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 KDO19275.1 - 0.9 9.5 8.3 1.2 9.2 2.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KDO19275.1 - 8.2 6.3 9.7 16 5.4 9.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KDO19276.1 - 3.7e-11 43.2 4.7 1e-10 41.7 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19276.1 - 1.9e-10 40.9 4.9 5e-10 39.5 4.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO19276.1 - 1.3e-07 31.3 3.9 2.6e-07 30.4 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO19276.1 - 6.7e-07 29.3 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-ANAPC11 PF12861.7 KDO19276.1 - 2.8e-06 27.3 6.0 4e-06 26.8 3.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO19276.1 - 5.9e-05 22.9 4.6 5.9e-05 22.9 4.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO19276.1 - 7e-05 22.8 2.2 0.00017 21.6 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO19276.1 - 7.6e-05 22.4 4.5 7.6e-05 22.4 4.5 2.4 2 1 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO19276.1 - 0.00021 21.1 15.5 0.00046 20.0 12.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KDO19276.1 - 0.00089 19.4 3.5 0.0061 16.7 3.5 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 KDO19276.1 - 0.016 15.0 2.6 0.034 14.0 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KDO19276.1 - 0.34 10.8 5.4 0.86 9.5 5.4 1.8 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KDO19276.1 - 1.4 8.8 10.5 3 7.8 8.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KDO19276.1 - 4.3 7.5 12.7 0.33 11.0 5.5 2.5 2 0 0 2 2 2 0 Zinc-finger Pkinase PF00069.25 KDO19278.1 - 1.1e-47 162.6 0.0 1.4e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19278.1 - 2.5e-43 148.3 0.0 3.3e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO19278.1 - 1.7e-06 27.6 0.3 3.4e-06 26.6 0.2 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO19278.1 - 4.6e-06 25.7 0.1 6.5e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO19278.1 - 0.0022 18.0 0.6 0.027 14.4 0.4 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO19278.1 - 0.18 11.1 0.0 0.19 11.0 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Dimer_Tnp_hAT PF05699.14 KDO19279.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SOG2 PF10428.9 KDO19280.1 - 0.42 9.8 6.4 0.52 9.5 6.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1418 PF07214.12 KDO19280.1 - 0.63 9.9 2.1 9.4 6.2 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) BNR PF02012.20 KDO19281.1 - 0.023 14.6 1.7 0.73 10.1 0.1 3.3 3 0 0 3 3 3 0 BNR/Asp-box repeat ETRAMP PF09716.10 KDO19281.1 - 0.041 13.9 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-CGNR PF11706.8 KDO19281.1 - 0.042 13.7 0.3 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 CGNR zinc finger Thaumatin PF00314.17 KDO19282.1 - 2.6e-05 23.9 6.8 0.011 15.4 1.7 3.1 1 1 1 2 2 2 2 Thaumatin family GHMP_kinases_N PF00288.26 KDO19285.1 - 4e-13 49.4 2.2 1.5e-12 47.6 2.2 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KDO19285.1 - 3.5e-06 27.3 0.0 9.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal zf-Nse PF11789.8 KDO19286.1 - 1.1e-14 53.9 0.2 2e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KDO19286.1 - 4.8e-05 23.1 0.1 9.7e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO19286.1 - 0.001 19.1 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 KDO19286.1 - 0.0021 18.2 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 KDO19286.1 - 0.0078 16.5 0.2 0.014 15.8 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19286.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 KDO19286.1 - 0.012 15.3 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.25 KDO19286.1 - 0.12 12.2 1.0 0.19 11.7 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CxC6 PF18721.1 KDO19287.1 - 0.41 11.0 9.5 1.6 9.1 7.3 2.2 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Indigoidine_A PF04227.12 KDO19288.1 - 1.3e-69 234.7 4.7 1.6e-69 234.5 4.7 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Aha1_N PF09229.11 KDO19289.1 - 1e-22 80.8 0.1 2.1e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF1079 PF06435.11 KDO19289.1 - 0.057 13.6 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) VHS PF00790.19 KDO19290.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 VHS domain BTK PF00779.19 KDO19292.1 - 0.11 12.4 4.3 0.056 13.3 1.0 2.1 2 0 0 2 2 2 0 BTK motif Pkinase PF00069.25 KDO19293.1 - 6.1e-54 183.2 0.0 8.8e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19293.1 - 1.8e-37 129.0 0.0 3.1e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-B_box PF00643.24 KDO19293.1 - 7e-06 26.1 2.9 1.4e-05 25.2 2.9 1.5 1 0 0 1 1 1 1 B-box zinc finger Pkinase_fungal PF17667.1 KDO19293.1 - 4.7e-05 22.3 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase SAM_1 PF00536.30 KDO19293.1 - 0.0046 17.4 0.2 0.016 15.6 0.2 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO19293.1 - 0.007 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CEBP_ZZ PF16366.5 KDO19293.1 - 0.013 15.7 2.9 0.029 14.6 2.9 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Kdo PF06293.14 KDO19293.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO19293.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KDO19294.1 - 1.1e-57 195.4 0.0 2.8e-55 187.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19294.1 - 1.1e-31 110.1 0.0 1.9e-29 102.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO19294.1 - 7.4e-06 25.0 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO19294.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO19294.1 - 0.0027 17.1 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO19294.1 - 0.0053 16.7 2.2 0.0061 16.5 0.3 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KDO19294.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PUL PF08324.11 KDO19296.1 - 0.025 13.8 3.0 0.086 12.1 3.0 1.7 1 1 0 1 1 1 0 PUL domain RabGAP-TBC PF00566.18 KDO19297.1 - 3.1e-28 98.9 2.5 7.2e-15 55.2 1.4 2.4 2 1 0 2 2 2 2 Rab-GTPase-TBC domain PH PF00169.29 KDO19297.1 - 0.053 14.0 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 PH domain Cnn_1N PF07989.11 KDO19298.1 - 0.0028 17.8 5.0 2.9 8.1 0.0 2.8 2 1 0 2 2 2 2 Centrosomin N-terminal motif 1 Isochorismatase PF00857.20 KDO19298.1 - 0.019 15.2 0.2 0.037 14.2 0.1 1.4 1 1 0 1 1 1 0 Isochorismatase family Syntaxin-6_N PF09177.11 KDO19298.1 - 0.065 13.8 3.7 0.086 13.4 3.7 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 KDO19298.1 - 0.087 12.9 7.6 3.7 7.7 0.3 2.7 1 1 1 2 2 2 0 bZIP transcription factor TPD52 PF04201.15 KDO19298.1 - 0.11 12.2 3.1 0.17 11.5 3.1 1.4 1 0 0 1 1 1 0 Tumour protein D52 family FlaC_arch PF05377.11 KDO19298.1 - 0.11 12.9 1.8 0.51 10.8 0.3 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) NEMO PF11577.8 KDO19298.1 - 0.19 11.8 7.8 0.4 10.7 7.1 2.0 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO FAM76 PF16046.5 KDO19298.1 - 0.47 9.8 6.1 0.54 9.6 6.1 1.1 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 KDO19298.1 - 0.48 10.5 14.4 0.65 10.1 11.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KDO19298.1 - 0.77 10.2 17.3 0.56 10.7 1.3 3.1 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 KDO19298.1 - 0.85 9.7 14.0 2 8.6 3.3 3.3 2 1 1 3 3 3 0 Basic region leucine zipper Retrotrans_gag PF03732.17 KDO19298.1 - 1.7 9.0 7.7 2.4 8.5 0.6 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Macoilin PF09726.9 KDO19298.1 - 2 6.8 11.2 2.4 6.6 11.2 1.0 1 0 0 1 1 1 0 Macoilin family Csm1_N PF18504.1 KDO19298.1 - 2.2 8.7 12.4 1.7 9.0 5.4 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain PX PF00787.24 KDO19299.1 - 2.5e-18 66.1 0.3 4.1e-18 65.4 0.3 1.4 1 0 0 1 1 1 1 PX domain DUF4609 PF15382.6 KDO19299.1 - 0.051 13.5 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) Prominin PF05478.11 KDO19300.1 - 3.5e-08 31.9 5.7 9.8e-06 23.8 0.0 2.6 3 0 0 3 3 3 2 Prominin Med4 PF10018.9 KDO19302.1 - 1e-17 64.5 0.8 2.2e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 1-cysPrx_C PF10417.9 KDO19302.1 - 0.00017 21.4 0.3 0.16 11.9 0.1 2.7 2 0 0 2 2 2 2 C-terminal domain of 1-Cys peroxiredoxin DUF4794 PF16042.5 KDO19302.1 - 0.31 12.0 3.7 5.9 7.9 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4794) BBP1_C PF15272.6 KDO19302.1 - 0.43 10.4 6.2 0.051 13.4 2.0 1.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Vma12 PF11712.8 KDO19303.1 - 1.6e-14 54.2 0.9 2e-14 53.8 0.9 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4407 PF14362.6 KDO19303.1 - 0.00078 18.9 0.7 0.00078 18.9 0.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) PelG PF16933.5 KDO19303.1 - 0.0087 15.0 0.3 0.011 14.6 0.3 1.1 1 0 0 1 1 1 1 Putative exopolysaccharide Exporter (EPS-E) DUF1772 PF08592.11 KDO19303.1 - 0.015 15.6 0.4 0.028 14.7 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) ArsP_1 PF03773.13 KDO19303.1 - 0.041 13.0 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Predicted permease ATP-grasp_3 PF02655.14 KDO19303.1 - 0.089 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Holin_BhlA PF10960.8 KDO19303.1 - 0.81 9.7 3.7 14 5.7 0.1 2.3 2 0 0 2 2 2 0 BhlA holin family PX PF00787.24 KDO19305.1 - 0.00092 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 PX domain MFS_1 PF07690.16 KDO19306.1 - 5.5e-14 51.9 19.8 5.5e-14 51.9 19.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KDO19307.1 - 9.1e-13 47.8 26.5 9.1e-13 47.8 26.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily AAA PF00004.29 KDO19308.1 - 1e-05 26.0 0.0 1.9e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KDO19308.1 - 1.7e-05 24.8 0.1 3.9e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO19308.1 - 8.5e-05 23.0 0.1 0.0003 21.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain FHA PF00498.26 KDO19308.1 - 0.00042 20.6 0.0 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain CHAT PF12770.7 KDO19308.1 - 0.00048 19.6 0.7 0.00081 18.9 0.7 1.5 1 0 0 1 1 1 1 CHAT domain IstB_IS21 PF01695.17 KDO19308.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO19308.1 - 0.003 17.8 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO19308.1 - 0.016 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO19308.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KDO19308.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KDO19308.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 NTPase Ribosomal_L36 PF00444.18 KDO19308.1 - 0.21 11.8 0.3 0.53 10.5 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L36 zf-C2H2 PF00096.26 KDO19310.1 - 7.7e-19 67.0 22.4 8.6e-06 25.9 0.8 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO19310.1 - 1.9e-17 62.8 14.4 1.1e-05 25.6 0.8 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO19310.1 - 2.1e-13 49.8 19.7 0.001 19.7 0.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KDO19310.1 - 8.3e-06 26.0 7.2 0.094 13.0 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KDO19310.1 - 3.2e-05 24.2 7.8 0.042 14.1 0.9 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 KDO19310.1 - 0.00012 22.3 1.8 0.028 14.8 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KDO19310.1 - 0.0096 15.9 0.2 0.0096 15.9 0.2 3.0 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KDO19310.1 - 0.093 12.5 5.1 2.4 8.0 0.3 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KDO19310.1 - 0.095 13.3 7.3 2.5 8.8 0.4 3.7 3 1 0 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KDO19310.1 - 1.8 9.3 7.6 2.5 8.8 0.7 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2 PF00096.26 KDO19311.1 - 2e-19 68.9 28.0 3.8e-07 30.2 1.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO19311.1 - 3.6e-14 52.2 24.6 3.8e-05 24.1 0.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO19311.1 - 2.1e-11 43.7 24.9 0.0025 18.2 0.3 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 KDO19311.1 - 0.00013 22.1 11.3 0.066 13.5 2.1 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KDO19311.1 - 0.001 18.8 13.6 0.0022 17.7 2.3 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KDO19311.1 - 0.0019 18.5 1.6 0.0019 18.5 1.6 2.3 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 KDO19311.1 - 0.0062 16.6 13.3 0.89 9.7 1.3 4.5 3 1 1 4 4 4 2 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 KDO19311.1 - 0.017 15.4 14.2 0.44 10.9 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CCHC_2 PF13696.6 KDO19311.1 - 0.03 14.1 0.6 0.074 12.9 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_9 PF16293.5 KDO19311.1 - 0.036 13.9 0.2 0.036 13.9 0.2 2.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KDO19311.1 - 0.037 14.0 19.1 0.046 13.7 0.5 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KDO19311.1 - 0.037 14.6 12.9 1.1 9.9 0.9 3.9 1 1 3 4 4 4 0 FOXP coiled-coil domain GAGA PF09237.11 KDO19311.1 - 0.063 13.1 4.9 0.26 11.1 0.2 2.5 2 0 0 2 2 2 0 GAGA factor Zn-C2H2_12 PF18112.1 KDO19311.1 - 0.085 13.3 5.0 98 3.6 0.2 4.4 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Ribosomal_L28 PF00830.19 KDO19311.1 - 0.15 12.3 2.0 1.6 9.0 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L28 family zf-met PF12874.7 KDO19311.1 - 0.21 12.1 0.2 0.21 12.1 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KDO19311.1 - 0.39 10.7 0.1 0.39 10.7 0.1 3.8 4 1 0 4 4 3 0 zinc-finger of a C2HC-type zf-RRN7 PF11781.8 KDO19311.1 - 0.63 9.8 0.1 0.63 9.8 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-H2C2_5 PF13909.6 KDO19311.1 - 0.66 9.8 15.6 5.4 6.9 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KDO19311.1 - 1.7 8.7 8.5 1.3 9.1 0.2 3.2 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KDO19312.1 - 4.4e-20 71.0 23.9 1.2e-06 28.7 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO19312.1 - 5.1e-15 54.9 21.4 0.00016 22.3 0.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO19312.1 - 2.2e-12 46.8 20.7 0.0054 17.1 0.3 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KDO19312.1 - 6.5e-05 23.2 10.7 0.017 15.4 3.1 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KDO19312.1 - 0.00041 20.6 3.9 0.00063 20.0 1.6 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KDO19312.1 - 0.0024 18.1 15.0 0.41 11.0 0.3 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KDO19312.1 - 0.003 18.1 11.5 0.78 10.4 0.8 3.8 2 1 2 4 4 4 2 FOXP coiled-coil domain zf_ZIC PF18366.1 KDO19312.1 - 0.019 15.0 8.7 0.67 10.1 0.1 4.3 4 0 0 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 KDO19312.1 - 0.042 13.6 11.9 0.21 11.4 1.3 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KDO19312.1 - 0.14 12.9 5.2 0.79 10.4 0.4 2.4 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KDO19312.1 - 0.14 12.0 4.7 0.44 10.4 0.1 3.4 3 2 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF4764 PF15961.5 KDO19312.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_aberr PF17017.5 KDO19312.1 - 0.21 11.7 8.1 0.77 9.9 0.1 3.4 1 1 3 4 4 4 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KDO19312.1 - 0.25 11.1 11.2 5.1 6.9 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain CpXC PF14353.6 KDO19312.1 - 0.77 9.8 3.7 6.5 6.8 0.1 2.6 1 1 1 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.6 KDO19312.1 - 3.7 7.6 19.0 0.64 10.1 0.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KDO19313.1 - 1.2e-21 75.9 19.8 6e-06 26.4 0.3 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO19313.1 - 1.1e-16 60.1 18.0 0.00014 22.4 0.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO19313.1 - 1.5e-15 56.8 20.9 4.4e-07 30.0 0.4 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KDO19313.1 - 1.4e-06 28.4 13.7 0.021 15.1 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KDO19313.1 - 8.7e-05 22.8 6.0 0.017 15.4 2.7 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 KDO19313.1 - 0.00092 19.5 12.5 0.0025 18.2 0.2 3.5 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KDO19313.1 - 0.0015 18.5 0.2 0.0015 18.5 0.2 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger DUF4764 PF15961.5 KDO19313.1 - 0.0015 17.3 0.1 0.0019 17.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) zf-C2H2_aberr PF17017.5 KDO19313.1 - 0.0031 17.7 7.0 0.36 11.0 0.1 3.1 1 1 0 2 2 2 2 Aberrant zinc-finger Tyr-DNA_phospho PF06087.12 KDO19313.1 - 0.0062 15.5 0.0 0.0071 15.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-C2H2_11 PF16622.5 KDO19313.1 - 0.047 13.5 6.5 0.9 9.4 0.5 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KDO19313.1 - 0.086 12.5 0.9 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KDO19313.1 - 0.093 13.0 7.1 0.34 11.2 0.8 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KDO19313.1 - 0.097 12.4 14.0 1.5 8.6 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KDO19313.1 - 0.11 12.8 5.0 0.085 13.2 0.9 2.2 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 KDO19313.1 - 0.81 10.4 8.8 2.5 8.9 1.3 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 KDO19313.1 - 1.8 9.3 8.7 5.9 7.6 0.3 3.8 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KDO19314.1 - 3.8e-20 71.3 22.2 2.7e-07 30.7 1.2 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KDO19314.1 - 5.1e-20 70.8 24.6 8.2e-06 26.0 0.5 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO19314.1 - 1.6e-14 53.3 22.3 0.0016 19.1 0.3 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KDO19314.1 - 1.1e-06 28.7 13.0 0.067 13.5 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO19314.1 - 3.4e-05 24.1 4.9 0.11 12.9 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type GAGA PF09237.11 KDO19314.1 - 0.00035 20.3 3.1 0.44 10.4 0.2 3.0 3 1 0 3 3 3 2 GAGA factor zf-C2H2_aberr PF17017.5 KDO19314.1 - 0.0012 19.0 5.2 0.21 11.7 0.1 3.0 1 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_9 PF16293.5 KDO19314.1 - 0.0044 16.8 0.1 1 9.3 0.0 3.1 3 0 0 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KDO19314.1 - 0.008 16.5 8.7 0.16 12.3 5.9 2.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KDO19314.1 - 0.013 16.1 10.9 2.5 8.8 0.9 3.9 1 1 3 4 4 4 0 FOXP coiled-coil domain Tyr-DNA_phospho PF06087.12 KDO19314.1 - 0.014 14.3 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase DUF4764 PF15961.5 KDO19314.1 - 0.023 13.4 0.1 0.035 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Vps36-NZF-N PF16988.5 KDO19314.1 - 0.03 13.7 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Di19 PF05605.12 KDO19314.1 - 0.03 14.6 11.6 0.075 13.3 2.1 3.0 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.18 KDO19314.1 - 0.057 14.1 8.4 2 9.2 1.4 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_6 PF13912.6 KDO19314.1 - 0.057 13.4 0.2 0.057 13.4 0.2 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf_UBZ PF18439.1 KDO19314.1 - 0.079 12.6 1.3 7.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RAG1 PF10426.9 KDO19314.1 - 0.15 12.3 0.2 7.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_11 PF16622.5 KDO19314.1 - 0.3 10.9 8.8 1 9.2 0.5 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KDO19314.1 - 0.48 10.8 4.2 0.54 10.6 0.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KDO19314.1 - 1.1 9.7 6.9 19 5.8 0.0 4.1 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KDO19314.1 - 1.4 8.8 13.7 12 5.8 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain IBR PF01485.21 KDO19314.1 - 8.7 6.7 11.8 48 4.3 8.7 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Pyrid_oxidase_2 PF13883.6 KDO19315.1 - 1.9e-42 145.1 0.0 2.5e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KDO19315.1 - 2.5e-07 30.8 0.0 5.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SPDY PF03771.16 KDO19315.1 - 0.036 14.0 1.7 0.18 11.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF317) CCB1 PF12046.8 KDO19315.1 - 0.062 12.6 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF2613 PF11021.8 KDO19315.1 - 0.45 10.7 4.5 0.33 11.1 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) BT1 PF03092.16 KDO19316.1 - 1.5e-14 53.2 14.7 1.8e-14 52.9 0.8 2.7 1 1 0 3 3 3 2 BT1 family MFS_1 PF07690.16 KDO19316.1 - 1.7e-06 27.2 34.0 1.7e-06 27.2 34.0 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1634 PF07843.11 KDO19316.1 - 1.5 8.9 9.1 2.6 8.2 1.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1634) Ank_4 PF13637.6 KDO19317.1 - 0.05 14.2 1.4 0.42 11.3 0.2 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF1843 PF08898.10 KDO19317.1 - 0.83 10.2 3.9 1.1 9.8 0.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) Pkinase PF00069.25 KDO19318.1 - 9e-71 238.3 0.0 1.1e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19318.1 - 7e-34 117.3 0.0 9.5e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KDO19318.1 - 4.8e-07 30.4 2.2 3.7e-05 24.3 0.8 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KDO19318.1 - 0.004 16.5 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PX PF00787.24 KDO19318.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 PX domain Haspin_kinase PF12330.8 KDO19318.1 - 0.051 12.5 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KDO19318.1 - 0.19 11.3 0.0 3 7.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HECT PF00632.25 KDO19321.1 - 1.4e-53 182.4 0.0 2.2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.6 KDO19321.1 - 6.6e-19 68.6 0.4 8.3e-12 45.5 0.0 4.0 3 1 1 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily MIB_HERC2 PF06701.13 KDO19321.1 - 3.7e-15 55.9 0.5 3.7e-15 55.9 0.5 3.1 3 0 0 3 3 3 1 Mib_herc2 SPRY PF00622.28 KDO19321.1 - 4.6e-12 46.1 0.0 1.3e-10 41.5 0.0 2.5 2 0 0 2 2 2 1 SPRY domain SH3_2 PF07653.17 KDO19321.1 - 0.2 11.3 0.0 0.67 9.7 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain SDA1 PF05285.12 KDO19321.1 - 0.28 10.6 3.4 0.5 9.7 3.4 1.2 1 0 0 1 1 1 0 SDA1 HEAT_2 PF13646.6 KDO19321.1 - 0.41 11.1 9.0 0.14 12.6 0.3 4.1 3 0 0 3 3 3 0 HEAT repeats Nop14 PF04147.12 KDO19321.1 - 8.9 4.4 7.8 14 3.7 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family TSP_1 PF00090.19 KDO19322.1 - 2.6e-10 40.4 152.3 3.5e-06 27.1 4.0 14.8 13 1 1 14 14 14 9 Thrombospondin type 1 domain PTN_MK_C PF01091.18 KDO19322.1 - 0.0024 18.2 4.2 0.022 15.2 0.2 12.8 10 3 2 13 13 13 6 PTN/MK heparin-binding protein family, C-terminal domain Defensin_2 PF01097.18 KDO19322.1 - 3.1 7.8 11.0 1.9 8.5 0.0 5.2 4 0 0 4 4 4 0 Arthropod defensin DnaJ-X PF14308.6 KDO19323.1 - 1.4e-39 135.7 4.5 1.4e-39 135.7 4.5 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KDO19323.1 - 4.6e-26 90.7 0.3 1.5e-25 89.1 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 KDO19323.1 - 6.9e-05 23.1 0.1 0.00024 21.4 0.1 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain HECT PF00632.25 KDO19324.1 - 3.6e-45 154.8 0.0 7.2e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.6 KDO19324.1 - 8.3e-20 71.5 0.0 7.2e-11 42.5 0.0 4.3 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily MIB_HERC2 PF06701.13 KDO19324.1 - 1.4e-16 60.5 18.4 2.7e-14 53.2 7.1 2.7 2 0 0 2 2 2 2 Mib_herc2 SPRY PF00622.28 KDO19324.1 - 3.4e-14 53.0 0.0 1.1e-12 48.1 0.0 2.6 2 0 0 2 2 2 1 SPRY domain CUB PF00431.20 KDO19324.1 - 1.9e-12 47.5 0.0 0.13 12.6 0.0 4.6 4 0 0 4 4 4 3 CUB domain UBA PF00627.31 KDO19324.1 - 0.0017 18.2 1.2 0.0029 17.5 0.3 2.0 2 0 0 2 2 2 1 UBA/TS-N domain SH3_3 PF08239.11 KDO19324.1 - 0.0089 16.3 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KDO19324.1 - 0.28 11.0 1.2 0.95 9.3 1.2 2.0 1 0 0 1 1 1 0 Bacterial SH3 domain Myotub-related PF06602.14 KDO19325.1 - 1e-130 435.8 0.0 1.4e-130 435.3 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KDO19325.1 - 0.0007 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KDO19325.1 - 0.0041 16.9 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO19325.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CHAP PF05257.16 KDO19326.1 - 1.1e-12 48.3 0.1 1.8e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 CHAP domain DUF4774 PF15999.5 KDO19327.1 - 0.12 12.2 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) Ank PF00023.30 KDO19330.1 - 4.3e-73 238.8 4.9 3.6e-08 33.5 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank_2 PF12796.7 KDO19330.1 - 2.6e-71 236.2 1.0 7.6e-17 61.7 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19330.1 - 9e-60 198.3 0.8 1.1e-09 38.7 0.0 8.9 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19330.1 - 1.3e-53 172.6 0.1 3.8e-05 23.8 0.0 10.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 KDO19330.1 - 2.3e-47 158.5 12.0 1.5e-10 41.1 0.1 7.3 2 2 3 7 7 7 7 Ankyrin repeats (many copies) PEGA PF08308.11 KDO19330.1 - 1.6e-06 27.9 1.2 11 6.0 0.0 6.8 6 1 1 7 7 7 1 PEGA domain T6SS-SciN PF12790.7 KDO19330.1 - 0.02 14.6 1.6 25 4.6 0.0 4.4 5 0 0 5 5 5 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 LuxT_C PF18285.1 KDO19330.1 - 0.044 14.3 0.1 38 4.9 0.0 4.0 2 1 1 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Ser_hydrolase PF06821.13 KDO19330.1 - 0.13 12.1 3.1 37 4.1 0.1 4.6 3 2 2 5 5 5 0 Serine hydrolase Nse4-Nse3_bdg PF15412.6 KDO19330.1 - 1.1 9.4 2.7 30 4.8 0.0 3.7 5 0 0 5 5 5 0 Binding domain of Nse4/EID3 to Nse3-MAGE MMR_HSR1 PF01926.23 KDO19334.1 - 4.7e-21 75.0 0.2 1e-20 73.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO19334.1 - 3.6e-10 39.7 0.1 7.6e-08 32.1 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KDO19334.1 - 1e-09 38.7 2.1 9.2e-05 22.6 0.1 2.6 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 KDO19334.1 - 8.4e-09 35.1 0.3 1.6e-08 34.2 0.3 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KDO19334.1 - 9.2e-09 34.9 0.2 1.8e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 AIG1 family KH_2 PF07650.17 KDO19334.1 - 7.1e-08 32.2 0.3 2e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 KH domain RsgA_GTPase PF03193.16 KDO19334.1 - 2e-05 24.5 0.5 0.027 14.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KDO19334.1 - 0.00082 19.7 0.1 0.0029 17.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain Arf PF00025.21 KDO19334.1 - 0.0015 18.0 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO19334.1 - 0.0019 17.6 0.1 0.0047 16.3 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KDO19334.1 - 0.0027 17.5 0.1 0.03 14.1 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GBP PF02263.19 KDO19334.1 - 0.018 14.3 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Roc PF08477.13 KDO19334.1 - 0.03 14.5 0.0 0.081 13.2 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KDO19334.1 - 0.06 12.9 1.6 0.28 10.8 0.7 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KDO19334.1 - 0.11 11.8 0.1 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Septin KH_1 PF00013.29 KDO19334.1 - 0.18 11.7 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 KH domain EXS PF03124.14 KDO19335.1 - 1e-65 222.3 21.5 1.8e-65 221.5 21.5 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KDO19335.1 - 1.1e-11 45.3 12.4 2.1e-06 27.9 0.3 3.1 1 1 2 3 3 3 3 SPX domain NUC130_3NT PF08158.12 KDO19335.1 - 0.00027 21.2 0.1 0.0008 19.7 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain SNF2_N PF00176.23 KDO19336.1 - 9e-46 156.2 0.0 5.1e-45 153.7 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO19336.1 - 2.5e-15 56.8 0.0 4.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KDO19336.1 - 0.0015 17.7 0.0 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Macro PF01661.21 KDO19336.1 - 0.0024 17.9 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 Macro domain ResIII PF04851.15 KDO19336.1 - 0.0041 17.2 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KDO19336.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase EXS PF03124.14 KDO19337.1 - 3.8e-70 236.8 23.1 3.8e-70 236.8 23.1 1.6 2 0 0 2 2 2 1 EXS family SPX PF03105.19 KDO19337.1 - 2.3e-10 40.9 11.4 2.4e-06 27.7 3.0 3.1 1 1 2 3 3 3 3 SPX domain EXS PF03124.14 KDO19338.1 - 4e-44 151.3 18.9 1.9e-23 83.3 7.0 2.7 2 1 1 3 3 3 2 EXS family SPX PF03105.19 KDO19338.1 - 2.4e-13 50.8 6.3 1.4e-05 25.2 2.7 3.1 1 1 2 3 3 3 3 SPX domain Exotox-A_target PF09102.10 KDO19338.1 - 0.084 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Exotoxin A, targeting MFS_1 PF07690.16 KDO19339.1 - 9.7e-06 24.7 17.6 9.8e-05 21.4 11.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Toxin_GhoT_OrtT PF10753.9 KDO19339.1 - 0.046 14.0 1.7 1.1 9.6 0.3 3.0 2 0 0 2 2 2 0 Toxin GhoT_OrtT MgtE PF01769.16 KDO19339.1 - 9.1 6.7 10.7 13 6.2 3.5 2.7 2 1 0 2 2 2 0 Divalent cation transporter BT1 PF03092.16 KDO19340.1 - 2e-15 56.0 19.5 2e-10 39.5 0.9 3.4 2 1 1 3 3 3 3 BT1 family MFS_1 PF07690.16 KDO19341.1 - 0.041 12.8 7.5 0.082 11.8 1.6 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily ATP_bind_3 PF01171.20 KDO19342.1 - 4.2e-38 130.9 0.0 6e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 KDO19342.1 - 1.5e-05 24.6 0.0 0.0051 16.3 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KDO19342.1 - 3.2e-05 23.2 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KDO19342.1 - 7e-05 22.7 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 KDO19342.1 - 0.00038 19.4 0.0 0.0006 18.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KDO19342.1 - 0.004 16.8 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KDO19342.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family RPA_interact_N PF14766.6 KDO19342.1 - 0.15 11.7 2.3 0.14 11.8 0.8 1.8 2 0 0 2 2 2 0 Replication protein A interacting N-terminal TSNAXIP1_N PF15739.5 KDO19346.1 - 9.9e-13 48.4 3.1 9.9e-13 48.4 3.1 3.1 1 1 2 3 3 3 1 Translin-associated factor X-interacting N-terminus KASH_CCD PF14662.6 KDO19346.1 - 0.0062 16.4 16.7 0.11 12.3 4.3 2.6 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH TcdB_N PF12918.7 KDO19346.1 - 0.026 14.8 0.8 4.9 7.5 0.2 3.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain NPV_P10 PF05531.12 KDO19346.1 - 0.11 13.0 5.1 0.23 12.0 1.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.13 KDO19346.1 - 0.13 12.2 6.7 0.11 12.5 2.7 2.6 1 1 1 2 2 2 0 Sec20 GAS PF13851.6 KDO19346.1 - 0.15 11.4 19.2 0.23 10.8 2.7 3.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 KDO19346.1 - 0.75 9.9 16.0 1.2 9.2 10.7 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Exonuc_VII_L PF02601.15 KDO19346.1 - 0.83 9.2 10.6 1.3 8.5 10.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_Mu_Gam PF07352.12 KDO19346.1 - 1.3 8.9 8.0 0.44 10.4 3.9 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein CENP-H PF05837.12 KDO19346.1 - 2.3 8.7 14.6 2.6 8.5 2.9 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) THOC7 PF05615.13 KDO19346.1 - 2.6 8.3 11.5 1.9 8.7 9.4 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 STAT_int PF02865.17 KDO19346.1 - 6.2 7.3 11.0 3.6 8.1 1.0 2.9 1 1 1 2 2 2 0 STAT protein, protein interaction domain APG6_N PF17675.1 KDO19346.1 - 7.3 7.1 18.4 4.2e+02 1.4 18.3 3.0 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-RING_2 PF13639.6 KDO19347.1 - 3.7e-13 49.6 5.5 9.2e-13 48.3 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19347.1 - 2.9e-09 37.1 7.0 9.1e-09 35.5 7.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO19347.1 - 2.2e-08 33.8 6.4 7.4e-08 32.1 6.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO19347.1 - 1.1e-07 31.6 3.6 2e-07 30.8 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO19347.1 - 2.7e-07 30.3 3.8 7e-07 29.0 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO19347.1 - 5.9e-07 29.4 2.3 1.4e-06 28.3 2.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger PX PF00787.24 KDO19347.1 - 2.4e-06 27.5 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 KDO19347.1 - 3.8e-06 26.5 2.5 1.2e-05 25.0 2.5 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO19347.1 - 7.8e-05 22.5 3.6 7.8e-05 22.5 3.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO19347.1 - 0.00028 20.9 3.5 0.00071 19.6 3.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO19347.1 - 0.0055 16.3 6.3 0.015 14.9 6.3 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO19347.1 - 0.0091 15.8 6.4 0.017 15.0 4.0 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KDO19347.1 - 0.011 15.7 2.5 0.011 15.7 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 KDO19347.1 - 0.015 15.4 2.6 0.17 12.1 2.6 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KDO19347.1 - 0.02 15.0 4.4 0.02 15.0 4.4 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KDO19347.1 - 0.11 12.6 3.9 0.32 11.2 3.9 1.8 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 KDO19347.1 - 0.17 11.8 1.7 0.43 10.4 1.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KDO19347.1 - 1.2 9.3 5.6 6.5 7.0 5.9 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 Zf_RING PF16744.5 KDO19347.1 - 1.9 8.6 5.5 1.7 8.8 2.8 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger AMP-binding PF00501.28 KDO19348.1 - 2.9e-20 72.3 0.7 3.8e-20 71.9 0.7 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PBECR3 PF18812.1 KDO19348.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 zf-RING_2 PF13639.6 KDO19349.1 - 5.6e-12 45.8 11.4 1.1e-11 44.9 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO19349.1 - 2.6e-09 36.9 2.3 2.6e-09 36.9 2.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO19349.1 - 3.6e-08 33.0 5.5 3.6e-08 33.0 5.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO19349.1 - 9e-06 25.9 13.6 3.1e-05 24.2 13.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KDO19349.1 - 2e-05 24.3 8.8 4.5e-05 23.2 8.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO19349.1 - 2.2e-05 24.2 10.6 4.2e-05 23.3 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO19349.1 - 2.7e-05 23.9 12.8 8.8e-05 22.3 12.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO19349.1 - 0.00054 19.9 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Prok-RING_4 PF14447.6 KDO19349.1 - 0.0083 16.0 10.6 0.064 13.1 10.7 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO19349.1 - 0.0084 16.0 8.8 0.016 15.1 8.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 KDO19349.1 - 0.25 11.5 10.3 2.3 8.5 10.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KDO19349.1 - 0.48 10.5 10.5 2.7 8.1 10.5 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KDO19349.1 - 0.92 9.7 10.9 1.7 8.8 6.4 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KDO19350.1 - 1.2e-12 47.9 5.4 2.7e-12 46.8 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19350.1 - 1.4e-09 38.1 6.0 4.5e-09 36.5 6.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO19350.1 - 3.5e-07 30.2 1.9 3.5e-07 30.2 1.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO19350.1 - 7e-07 29.1 4.3 1.7e-06 27.8 4.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO19350.1 - 1e-06 28.5 4.0 1.9e-06 27.6 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO19350.1 - 1.6e-06 27.8 7.0 6.7e-06 25.8 7.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO19350.1 - 2e-06 27.7 0.9 2e-06 27.7 0.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO19350.1 - 1.1e-05 25.0 4.0 1.1e-05 25.0 4.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 KDO19350.1 - 1.3e-05 25.3 3.3 9.5e-05 22.5 3.3 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KDO19350.1 - 6.2e-05 22.8 4.7 0.00014 21.6 4.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO19350.1 - 0.00082 18.9 6.3 0.0022 17.5 6.2 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO19350.1 - 0.0012 18.7 3.2 0.0051 16.6 2.9 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KDO19350.1 - 0.0029 17.4 5.1 0.019 14.8 5.3 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 PX PF00787.24 KDO19350.1 - 0.0041 17.1 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 PX domain Med27 PF11571.8 KDO19350.1 - 0.006 16.9 1.5 4.9 7.6 0.5 3.2 2 1 1 3 3 3 1 Mediator complex subunit 27 RINGv PF12906.7 KDO19350.1 - 0.098 12.8 5.9 0.27 11.4 5.9 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KDO19350.1 - 0.11 12.5 2.3 0.35 10.9 2.3 1.9 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 KDO19350.1 - 0.12 12.7 0.6 0.12 12.7 0.6 1.8 2 0 0 2 2 1 0 RING-like domain Prok-RING_1 PF14446.6 KDO19350.1 - 0.16 11.9 5.1 0.39 10.7 1.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RVT PF13966.6 KDO19350.1 - 1.4 9.7 5.2 13 6.6 0.6 3.5 4 0 0 4 4 4 0 zinc-binding in reverse transcriptase zf-C3HC4_4 PF15227.6 KDO19350.1 - 1.7 8.9 6.2 14 6.0 6.6 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KDO19351.1 - 1.4e-13 51.0 4.3 3.2e-13 49.8 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19351.1 - 1.6e-09 37.9 6.1 3.7e-09 36.7 6.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO19351.1 - 3.5e-08 33.3 1.8 1.4e-07 31.4 0.3 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO19351.1 - 9e-08 31.8 9.2 1.1e-07 31.6 6.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO19351.1 - 4.5e-07 29.5 3.4 7.7e-07 28.8 1.0 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO19351.1 - 5.3e-07 29.4 3.3 9.9e-07 28.5 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO19351.1 - 5.8e-07 29.4 3.9 1.3e-06 28.3 3.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 KDO19351.1 - 2.6e-06 27.5 1.7 1e-05 25.6 1.7 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KDO19351.1 - 2.7e-06 27.4 3.6 5e-06 26.5 2.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO19351.1 - 8.6e-05 22.3 5.3 0.0001 22.1 4.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO19351.1 - 0.0021 17.6 4.8 0.0046 16.5 4.8 1.6 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO19351.1 - 0.0095 15.8 11.3 0.018 14.9 8.3 2.5 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KDO19351.1 - 0.012 15.8 3.3 0.024 14.7 3.3 1.6 1 0 0 1 1 1 0 RING-variant domain PX PF00787.24 KDO19351.1 - 0.036 14.0 0.0 0.083 12.9 0.0 1.5 1 1 0 1 1 1 0 PX domain zf-RING_10 PF16685.5 KDO19351.1 - 0.038 14.1 4.6 0.038 14.1 4.6 1.8 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING-like PF08746.11 KDO19351.1 - 0.052 13.9 0.8 0.052 13.9 0.8 1.9 2 0 0 2 2 1 0 RING-like domain zf-Nse PF11789.8 KDO19351.1 - 0.14 12.0 4.6 0.62 9.9 2.2 2.4 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 KDO19351.1 - 0.71 9.9 6.3 0.45 10.5 0.4 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 KDO19351.1 - 0.94 9.7 7.8 8 6.7 3.6 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KDO19352.1 - 1.7e-10 41.1 5.3 3.5e-10 40.0 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19352.1 - 1.6e-07 31.5 6.6 4.3e-07 30.1 6.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO19352.1 - 7.2e-06 25.8 4.9 1.5e-05 24.8 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO19352.1 - 1.9e-05 24.4 6.4 5.2e-05 23.0 6.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO19352.1 - 2.1e-05 24.5 3.2 5.6e-05 23.1 3.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KDO19352.1 - 4.1e-05 23.2 7.1 0.00013 21.6 7.1 1.9 1 1 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KDO19352.1 - 6.1e-05 22.8 3.3 0.00016 21.4 3.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KDO19352.1 - 0.00013 21.9 1.8 0.00071 19.6 2.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO19352.1 - 0.00021 21.2 3.9 0.00044 20.1 3.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KDO19352.1 - 0.0021 17.6 5.4 0.0057 16.3 5.4 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KDO19352.1 - 0.0044 16.8 3.2 0.011 15.6 3.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KDO19352.1 - 0.0079 16.3 5.1 0.066 13.4 5.1 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KDO19352.1 - 0.012 15.6 3.2 0.042 13.9 3.2 1.9 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KDO19352.1 - 0.027 14.6 4.1 0.068 13.3 4.1 1.7 1 1 0 1 1 1 0 RING-variant domain UL41A PF17591.2 KDO19352.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A zf-Nse PF11789.8 KDO19352.1 - 0.2 11.5 3.2 0.17 11.7 1.3 2.1 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KDO19352.1 - 0.53 10.5 4.2 0.24 11.6 1.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING OTT_1508_deam PF14441.6 KDO19352.1 - 2.1 8.4 5.4 0.55 10.3 1.9 1.9 2 0 0 2 2 2 0 OTT_1508-like deaminase zf-RING_2 PF13639.6 KDO19353.1 - 4.3e-10 39.8 6.1 9.2e-10 38.7 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO19353.1 - 5e-08 33.1 9.1 2.3e-07 31.0 9.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO19353.1 - 3e-07 30.4 2.7 5.6e-07 29.5 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO19353.1 - 1.1e-05 25.3 4.5 1.9e-05 24.5 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO19353.1 - 2.5e-05 24.0 8.4 3.4e-05 23.6 2.3 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO19353.1 - 2.8e-05 23.9 5.8 6.1e-05 22.8 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO19353.1 - 6.3e-05 22.6 4.8 0.00014 21.5 4.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO19353.1 - 0.00018 21.3 11.1 0.0013 18.5 11.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO19353.1 - 0.00039 20.2 5.5 0.0017 18.1 5.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KDO19353.1 - 0.0044 17.0 2.4 0.0044 17.0 2.4 2.6 3 0 0 3 3 3 1 Zinc-finger zf-RING_UBOX PF13445.6 KDO19353.1 - 0.0065 16.5 7.8 0.013 15.5 7.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 KDO19353.1 - 0.046 13.6 1.6 0.17 11.7 1.6 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PX PF00787.24 KDO19353.1 - 0.085 12.9 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 PX domain FANCL_C PF11793.8 KDO19353.1 - 0.15 12.3 3.4 0.34 11.1 3.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KDO19353.1 - 0.41 10.3 10.9 0.92 9.2 9.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KDO19353.1 - 1.2 9.3 6.2 3.3 7.9 6.2 1.7 1 1 0 1 1 1 0 RING-variant domain E6 PF00518.17 KDO19354.1 - 3.9 8.0 11.0 0.75 10.3 0.1 3.4 2 1 1 3 3 3 0 Early Protein (E6) CEBP_ZZ PF16366.5 KDO19356.1 - 0.019 15.2 2.2 0.039 14.2 2.2 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_14 PF17978.1 KDO19356.1 - 0.059 13.8 3.4 0.09 13.2 3.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KDO19356.1 - 0.44 10.8 7.6 0.21 11.8 4.2 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KDO19356.1 - 1.5 9.0 7.7 3.9 7.7 7.8 1.8 1 1 1 2 2 2 0 FYVE zinc finger IBR PF01485.21 KDO19357.1 - 8.2e-14 51.6 40.6 3.1e-08 33.7 17.8 3.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-B_box PF00643.24 KDO19357.1 - 3.4 7.9 38.6 1.3 9.3 4.3 4.6 4 1 0 4 4 4 0 B-box zinc finger IBR PF01485.21 KDO19358.1 - 3.3e-17 62.5 71.0 2.9e-08 33.8 6.4 6.4 5 1 1 6 6 6 4 IBR domain, a half RING-finger domain IBR PF01485.21 KDO19359.1 - 2.3e-12 47.0 49.4 1.1e-06 28.8 20.2 3.4 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 KDO19359.1 - 0.029 14.3 3.2 0.029 14.3 3.2 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain RNA_POL_M_15KD PF02150.16 KDO19359.1 - 0.037 13.9 0.6 0.037 13.9 0.6 4.0 2 2 1 3 3 3 0 RNA polymerases M/15 Kd subunit zf-RING_2 PF13639.6 KDO19359.1 - 3.4 8.1 51.8 0.9 9.9 9.9 4.4 3 1 1 4 4 4 0 Ring finger domain IBR PF01485.21 KDO19360.1 - 9.5e-14 51.4 54.2 1.5e-08 34.8 6.6 3.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-B_box PF00643.24 KDO19360.1 - 1.4 9.1 48.4 1.5 9.1 10.0 4.8 4 1 0 4 4 4 0 B-box zinc finger IBR PF01485.21 KDO19361.1 - 0.0027 17.9 10.1 0.0035 17.5 10.1 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Pkinase_Tyr PF07714.17 KDO19364.1 - 1.1e-46 159.3 0.0 1.5e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19364.1 - 6.9e-46 156.7 0.0 1.6e-45 155.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KDO19364.1 - 1.8e-06 27.6 4.2 0.0015 18.2 1.6 2.5 2 0 0 2 2 2 2 Leucine rich repeat Pkinase_fungal PF17667.1 KDO19364.1 - 0.013 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO19364.1 - 0.027 13.4 0.0 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain LRR_4 PF12799.7 KDO19364.1 - 0.032 14.7 12.0 1.4 9.5 2.4 3.2 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) APH PF01636.23 KDO19364.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 KDO19364.1 - 6.2 7.2 7.4 25 5.3 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase PF00069.25 KDO19365.1 - 9.8e-38 130.0 0.0 8.5e-37 126.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19365.1 - 5e-36 124.3 0.0 5.5e-35 120.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO19365.1 - 2.8e-05 24.2 0.1 0.016 15.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 KDO19365.1 - 0.0015 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase_fungal PF17667.1 KDO19365.1 - 0.067 11.9 0.0 0.13 11.1 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO19366.1 - 1.7e-48 165.2 0.0 2.3e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19366.1 - 1.1e-43 149.6 0.0 1.6e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 KDO19366.1 - 0.0031 16.9 3.1 0.0056 16.1 3.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 KDO19366.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3153 PF11353.8 KDO19366.1 - 0.18 11.4 1.1 1.2 8.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) IFT46_B_C PF12317.8 KDO19368.1 - 2.1e-46 158.4 0.0 2.9e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Cwf_Cwc_15 PF04889.12 KDO19368.1 - 0.067 12.9 13.5 0.097 12.4 13.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 KDO19368.1 - 0.52 10.3 3.2 0.77 9.8 3.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KDO19368.1 - 0.84 10.1 13.3 1.7 9.1 13.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 KDO19368.1 - 1.8 8.4 7.2 2.7 7.8 7.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.6 KDO19368.1 - 2.3 8.5 7.0 4.2 7.7 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KDO19368.1 - 2.9 5.9 9.8 4.1 5.4 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mid1 PF12929.7 KDO19369.1 - 6.4e-17 61.9 14.8 5.3e-13 48.9 6.3 2.0 1 1 0 2 2 2 2 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KDO19369.1 - 0.00089 19.9 9.8 0.011 16.3 9.8 2.4 1 1 0 1 1 1 1 Fz domain Adeno_PVIII PF01310.18 KDO19370.1 - 0.02 14.5 0.6 0.034 13.7 0.6 1.3 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII MSA-2c PF12238.8 KDO19370.1 - 0.13 12.2 1.2 0.29 11.1 1.2 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Spc7 PF08317.11 KDO19370.1 - 0.17 10.8 10.4 0.34 9.8 10.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 KDO19370.1 - 0.17 12.1 13.6 20 5.3 0.1 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) LicD PF04991.13 KDO19371.1 - 6.4e-19 69.0 0.0 6e-11 42.9 0.0 2.4 1 1 0 2 2 2 2 LicD family GCFC PF07842.12 KDO19372.1 - 0.00042 20.0 0.1 0.00072 19.3 0.1 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein AAA_27 PF13514.6 KDO19372.1 - 0.13 11.9 0.5 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 KDO19374.1 - 6.1e-14 52.7 0.1 1.4e-13 51.5 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_6 PF13516.6 KDO19375.1 - 9.7e-09 34.6 1.5 0.0021 18.0 0.0 3.3 3 0 0 3 3 3 3 Leucine Rich repeat LRR_8 PF13855.6 KDO19375.1 - 1.3e-06 28.1 0.9 0.0023 17.7 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO19375.1 - 4.2e-05 23.8 0.3 0.033 14.6 0.1 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO19375.1 - 0.0053 17.1 0.3 15 6.6 0.2 3.3 2 1 1 3 3 3 1 Leucine Rich Repeat Herpes_DNAp_acc PF04929.12 KDO19376.1 - 0.53 9.2 9.0 0.59 9.1 9.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Gly-zipper_Omp PF13488.6 KDO19377.1 - 0.0001 22.2 8.6 0.00017 21.5 8.6 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 KDO19377.1 - 0.0019 17.9 5.2 0.0034 17.1 5.2 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper EAL PF00563.20 KDO19377.1 - 0.031 13.8 0.2 0.046 13.2 0.2 1.3 1 0 0 1 1 1 0 EAL domain Gly-zipper_OmpA PF13436.6 KDO19377.1 - 0.045 13.5 6.2 0.079 12.8 6.2 1.3 1 0 0 1 1 1 0 Glycine-zipper domain Ribo_biogen_C PF04034.13 KDO19377.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal Rick_17kDa_Anti PF05433.15 KDO19377.1 - 0.23 11.4 12.3 0.47 10.4 12.3 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Peptidase_S8 PF00082.22 KDO19379.1 - 1.6e-36 126.1 0.0 3e-36 125.2 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PAN_4 PF14295.6 KDO19380.1 - 0.49 10.3 6.1 1.9 8.4 1.3 2.5 2 0 0 2 2 2 0 PAN domain YbfN PF13982.6 KDO19380.1 - 0.73 10.1 4.5 1.9 8.8 0.8 2.5 1 1 0 2 2 2 0 YbfN-like lipoprotein NIF PF03031.18 KDO19381.1 - 4.6e-57 192.2 0.2 6.1e-57 191.8 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Cyt-b5 PF00173.28 KDO19382.1 - 8.3e-21 73.9 0.1 1.1e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2996 PF11210.8 KDO19382.1 - 0.023 15.1 0.0 0.026 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) DZR PF12773.7 KDO19383.1 - 0.033 14.2 1.5 0.056 13.5 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Vps36-NZF-N PF16988.5 KDO19383.1 - 0.069 12.5 1.2 0.13 11.7 1.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_ribbon_SprT PF17283.2 KDO19383.1 - 0.26 11.2 0.2 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-RanBP PF00641.18 KDO19383.1 - 0.35 10.2 5.6 0.63 9.4 5.6 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Cyt-b5 PF00173.28 KDO19384.1 - 2.2e-20 72.6 0.1 3e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1298 PF06974.13 KDO19386.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) FYVE PF01363.21 KDO19387.1 - 3.7e-15 55.8 10.9 6.3e-15 55.1 10.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO19387.1 - 0.0031 17.7 6.0 0.004 17.3 6.0 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO19388.1 - 4.7e-10 39.5 9.8 4.7e-10 39.5 9.8 2.5 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO19388.1 - 0.00026 21.3 2.7 0.00026 21.3 2.7 3.5 3 1 1 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KDO19388.1 - 0.0014 18.3 4.0 0.0014 18.3 4.0 2.4 3 0 0 3 3 3 1 RING-like zinc finger Vps39_2 PF10367.9 KDO19388.1 - 0.034 14.6 1.4 0.034 14.6 1.4 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 FYVE_2 PF02318.16 KDO19388.1 - 0.44 10.8 10.6 0.18 12.0 6.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C2HC5 PF06221.13 KDO19388.1 - 0.9 9.6 9.9 9.2 6.3 7.5 3.0 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type PH PF00169.29 KDO19390.1 - 0.00049 20.6 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Apt1 PF10351.9 KDO19390.1 - 0.18 10.7 5.4 0.34 9.7 5.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nucleoporin_FG PF13634.6 KDO19391.1 - 0.12 13.3 10.0 0.12 13.3 8.0 1.9 2 0 0 2 2 2 0 Nucleoporin FG repeat region Ricin_B_lectin PF00652.22 KDO19392.1 - 2.7e-14 53.5 0.1 6.3e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO19392.1 - 0.00071 20.3 0.0 0.024 15.3 0.0 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CotJB PF12652.7 KDO19392.1 - 0.083 13.1 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 CotJB protein PRCC PF10253.9 KDO19392.1 - 0.83 10.4 6.8 1.2 9.9 6.8 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SPX PF03105.19 KDO19392.1 - 1.7 8.5 9.5 2.1 8.2 9.5 1.1 1 0 0 1 1 1 0 SPX domain DUF3530 PF12048.8 KDO19392.1 - 8.4 5.7 6.4 15 4.9 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) EF-hand_1 PF00036.32 KDO19393.1 - 2.4e-11 42.3 0.0 1.7e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO19393.1 - 5.7e-10 38.3 0.1 0.001 18.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO19393.1 - 1.6e-09 36.8 0.4 0.002 17.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO19393.1 - 3.4e-08 33.8 0.0 7.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO19393.1 - 6.4e-07 29.1 0.3 0.0059 16.4 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO19393.1 - 0.018 15.3 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain PAP_assoc PF03828.19 KDO19394.1 - 3.9e-12 46.2 0.8 6.9e-12 45.4 0.1 1.9 2 1 0 2 2 2 1 Cid1 family poly A polymerase Nrap_D2 PF17403.2 KDO19394.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain NTP_transf_2 PF01909.23 KDO19394.1 - 0.0073 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KDO19394.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PAP_central PF04928.17 KDO19394.1 - 0.1 11.5 0.2 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Poly(A) polymerase central domain RVT_1 PF00078.27 KDO19395.1 - 2.1e-07 30.7 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_14 PF13428.6 KDO19396.1 - 0.076 13.9 3.3 3.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO19396.1 - 0.085 13.2 0.3 2 8.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_membrane PF00664.23 KDO19398.1 - 0.00021 21.0 0.1 0.00052 19.7 0.1 1.8 2 1 0 2 2 2 1 ABC transporter transmembrane region Abhydrolase_4 PF08386.10 KDO19399.1 - 9.8e-05 22.4 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein VEGFR-2_TMD PF17988.1 KDO19399.1 - 0.0066 15.9 2.4 0.016 14.6 2.4 1.7 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain Mucin15 PF15672.5 KDO19399.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 RPAP3_C PF13877.6 KDO19399.1 - 0.2 12.2 0.0 0.42 11.2 0.0 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Gram_pos_anchor PF00746.21 KDO19399.1 - 3 7.9 6.4 0.41 10.6 1.8 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif GRDP-like PF07173.12 KDO19400.1 - 8.7e-16 58.9 0.1 1.7e-15 57.9 0.1 1.5 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Abhydrolase_4 PF08386.10 KDO19401.1 - 6.5e-05 23.0 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Podoplanin PF05808.11 KDO19401.1 - 0.0042 17.2 0.7 0.0042 17.2 0.7 1.7 2 0 0 2 2 2 1 Podoplanin Hydrolase_4 PF12146.8 KDO19401.1 - 0.021 14.1 0.0 0.27 10.4 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF4064 PF13273.6 KDO19401.1 - 0.089 13.1 0.2 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Abhydrolase_1 PF00561.20 KDO19401.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribonuclease_T2 PF00445.18 KDO19402.1 - 1.4e-29 103.6 0.4 1.8e-29 103.2 0.4 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Pex24p PF06398.11 KDO19403.1 - 0.00062 18.9 5.0 0.0016 17.5 5.0 1.6 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Vps62 PF06101.11 KDO19404.1 - 0.11 10.8 0.0 1.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 62 US22 PF02393.16 KDO19406.1 - 0.068 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 US22 like Pkinase_Tyr PF07714.17 KDO19407.1 - 7.6e-52 176.2 0.0 1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19407.1 - 5.1e-48 163.7 0.0 6.9e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO19407.1 - 0.0001 21.2 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO19407.1 - 0.00058 19.3 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO19407.1 - 0.25 10.2 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KDO19408.1 - 1e-27 97.1 0.0 1.2e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19408.1 - 1.1e-20 74.2 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO19408.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KDO19409.1 - 3.7e-47 160.8 0.0 4.9e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19409.1 - 6.4e-45 153.6 0.0 8.6e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO19409.1 - 0.00014 20.7 0.1 0.00021 20.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO19409.1 - 0.006 16.0 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4381 PF14316.6 KDO19409.1 - 0.015 15.5 0.4 0.038 14.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CrgA PF06781.12 KDO19409.1 - 0.045 13.8 0.0 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 Cell division protein CrgA Kinase-like PF14531.6 KDO19409.1 - 0.19 11.0 0.1 0.4 10.0 0.1 1.4 1 1 0 1 1 1 0 Kinase-like CcmD PF04995.14 KDO19409.1 - 0.52 10.4 4.0 1.4 9.1 4.0 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pkinase_Tyr PF07714.17 KDO19410.1 - 3e-36 125.0 0.0 1.8e-35 122.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19410.1 - 8.2e-36 123.7 0.0 1.1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO19410.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO19410.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO19410.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO19410.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2384 PF09722.10 KDO19411.1 - 0.069 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Pkinase PF00069.25 KDO19413.1 - 1.9e-43 148.7 0.0 2.8e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19413.1 - 2.3e-43 148.3 0.1 3.1e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO19413.1 - 9.4e-06 25.1 0.4 1.5e-05 24.4 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO19413.1 - 0.00022 20.3 0.8 0.00049 19.2 0.8 1.5 1 1 0 1 1 1 1 Haspin like kinase domain MGC-24 PF05283.11 KDO19413.1 - 0.019 15.4 1.2 0.019 15.4 1.2 2.4 1 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Kinase-like PF14531.6 KDO19413.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Kinase-like DUF4381 PF14316.6 KDO19413.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Gram_pos_anchor PF00746.21 KDO19413.1 - 0.12 12.4 0.4 0.27 11.2 0.4 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HTH_33 PF13592.6 KDO19416.1 - 0.16 11.7 0.7 0.25 11.0 0.7 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Cnd3 PF12719.7 KDO19418.1 - 4.9e-24 85.0 1.5 4.9e-24 85.0 1.5 1.9 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CCDC-167 PF15188.6 KDO19418.1 - 0.00037 20.8 0.9 0.001 19.3 0.9 1.8 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 VWA_2 PF13519.6 KDO19419.1 - 1.7e-11 44.7 0.3 1.1e-10 42.1 0.1 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KDO19419.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 KDO19419.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Disintegrin PF00200.23 KDO19420.1 - 4.4e-23 81.9 83.9 1.5e-05 25.7 6.1 8.1 5 4 1 6 6 6 6 Disintegrin Cir_N PF10197.9 KDO19423.1 - 0.0062 16.7 6.9 0.0062 16.7 6.9 3.4 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR E1-E2_ATPase PF00122.20 KDO19424.1 - 2.4e-26 92.4 1.8 6.1e-26 91.0 1.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KDO19424.1 - 1.8e-16 61.0 0.1 1.1e-08 35.7 0.0 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KDO19424.1 - 3.1e-10 40.2 1.8 8.4e-10 38.8 0.9 2.0 1 1 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 KDO19424.1 - 3.6e-07 29.8 0.0 7.9e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Catalase_C PF18011.1 KDO19424.1 - 0.026 14.2 0.0 2.4 7.8 0.0 3.2 3 0 0 3 3 3 0 C-terminal domain found in long catalases Cation_ATPase PF13246.6 KDO19424.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) LapA_dom PF06305.11 KDO19424.1 - 9.7 6.1 7.9 5.7 6.8 1.5 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_38N PF01074.22 KDO19426.1 - 1.3e-78 264.3 5.5 1.8e-78 263.8 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KDO19426.1 - 4.8e-32 111.8 0.0 9.6e-32 110.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KDO19426.1 - 4.1e-21 74.9 0.5 8.8e-21 73.9 0.5 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KDO19426.1 - 0.094 12.8 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Herpes_glycop PF01528.16 KDO19428.1 - 0.054 12.3 2.4 0.064 12.1 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PP2C PF00481.21 KDO19430.1 - 1.7e-63 214.6 0.0 2.1e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO19430.1 - 2.1e-07 30.8 0.0 5.1e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C RsmJ PF04378.13 KDO19431.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Spc24 PF08286.11 KDO19431.1 - 0.31 11.3 1.8 11 6.3 1.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TRAF_BIRC3_bd PF16673.5 KDO19432.1 - 0.052 13.4 0.1 20 5.1 0.0 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain GAS PF13851.6 KDO19433.1 - 0.018 14.4 3.7 0.36 10.1 0.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 KDO19433.1 - 0.021 15.1 0.3 0.021 15.1 0.3 1.9 2 0 0 2 2 2 0 Tup N-terminal JAKMIP_CC3 PF16034.5 KDO19433.1 - 0.039 13.9 2.4 0.087 12.8 2.4 1.6 1 0 0 1 1 1 0 JAKMIP CC3 domain Csm1_N PF18504.1 KDO19433.1 - 0.099 13.0 3.2 2 8.8 0.3 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc24 PF08286.11 KDO19433.1 - 0.58 10.4 2.3 1.1 9.5 2.3 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 KDO19433.1 - 0.72 10.1 3.6 3.8 7.8 2.3 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MerR-DNA-bind PF09278.11 KDO19433.1 - 6.2 7.4 9.2 1.2 9.8 0.7 3.2 2 1 1 3 3 3 0 MerR, DNA binding P21-Arc PF04062.14 KDO19434.1 - 0.12 12.4 1.6 10 6.1 0.0 2.2 2 0 0 2 2 2 0 ARP2/3 complex ARPC3 (21 kDa) subunit BBS2_C PF14782.6 KDO19434.1 - 0.28 9.9 1.1 0.45 9.2 1.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PX PF00787.24 KDO19435.1 - 0.0084 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF2120 PF09893.9 KDO19435.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) zf-CCCH_4 PF18044.1 KDO19437.1 - 5.2e-09 35.7 5.0 5.2e-09 35.7 5.0 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO19437.1 - 1.5e-07 31.2 8.6 3.6e-07 30.0 8.6 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KDO19437.1 - 2.9e-07 30.2 3.4 7.8e-07 28.8 3.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO19437.1 - 0.0014 19.3 1.2 0.0024 18.5 1.2 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 KDO19437.1 - 0.14 12.4 0.6 0.23 11.7 0.6 1.3 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KDO19437.1 - 2.2 8.9 9.4 0.93 10.1 6.2 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PH PF00169.29 KDO19438.1 - 1.3e-07 32.1 0.0 1.7e-05 25.3 0.0 2.8 3 0 0 3 3 3 2 PH domain DUF1043 PF06295.12 KDO19438.1 - 2.7 8.0 6.2 11 6.1 2.5 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1043) HAD_2 PF13419.6 KDO19439.1 - 1.2e-23 84.2 0.0 1.4e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO19439.1 - 3.9e-13 50.2 0.0 8.2e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KDO19439.1 - 0.0001 22.4 0.0 0.062 13.4 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO19439.1 - 0.00026 21.4 0.0 0.00034 21.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO19439.1 - 0.0097 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Utp21 PF04192.12 KDO19440.1 - 2.2e-45 155.0 0.0 7.4e-45 153.3 0.0 1.8 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KDO19440.1 - 1.4e-30 104.9 21.8 3.8e-10 40.2 2.7 10.6 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO19440.1 - 2e-16 60.0 0.0 9.2e-05 22.7 0.0 6.2 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO19440.1 - 1.9e-06 26.8 9.2 0.42 9.2 0.1 5.0 2 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KDO19440.1 - 1.4e-05 24.6 0.0 1.2 8.4 0.0 3.8 3 1 0 3 3 3 3 WD40-like domain Cytochrom_D1 PF02239.16 KDO19440.1 - 0.00074 18.2 0.0 0.0027 16.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Hira PF07569.11 KDO19440.1 - 0.022 14.5 1.9 14 5.3 0.0 4.2 5 0 0 5 5 5 0 TUP1-like enhancer of split HPS3_N PF14761.6 KDO19440.1 - 0.097 12.2 0.0 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 KDO19440.1 - 0.11 11.4 0.1 2.8 6.8 0.0 3.0 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M24 PF00557.24 KDO19442.1 - 4.7e-27 95.0 0.8 6.2e-27 94.6 0.8 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DZR PF12773.7 KDO19443.1 - 0.058 13.4 7.0 3.7 7.6 0.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon COPI_assoc PF08507.10 KDO19444.1 - 1.6e-13 50.8 8.7 2.2e-13 50.4 8.7 1.2 1 0 0 1 1 1 1 COPI associated protein Pox_P35 PF03213.14 KDO19444.1 - 0.032 13.5 2.4 0.048 12.9 2.4 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein S_4TM PF18159.1 KDO19444.1 - 0.096 12.0 2.7 0.15 11.3 2.7 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3784 PF12650.7 KDO19444.1 - 8.4 6.7 12.6 3.4 7.9 4.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) cNMP_binding PF00027.29 KDO19445.1 - 1.4e-09 37.9 0.1 5.8e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain FERM_M PF00373.18 KDO19445.1 - 0.039 14.3 0.5 0.12 12.8 0.1 2.1 2 1 0 2 2 2 0 FERM central domain CSRNP_N PF16019.5 KDO19446.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus RRM_1 PF00076.22 KDO19447.1 - 8.2e-81 265.8 0.3 5.2e-20 71.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KDO19447.1 - 9e-29 99.5 0.4 1.7e-27 95.4 0.3 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KDO19447.1 - 1e-08 34.8 0.0 0.02 14.5 0.0 3.8 2 2 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KDO19447.1 - 1.5e-06 28.1 0.2 1.8 8.6 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KDO19447.1 - 0.00044 20.3 0.0 9.7 6.4 0.0 4.1 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 KDO19447.1 - 0.00076 19.5 0.2 8.3 6.5 0.1 4.1 4 0 0 4 4 4 1 RNA binding motif SET_assoc PF11767.8 KDO19447.1 - 0.0032 17.1 0.1 8.1 6.2 0.0 3.7 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated DUF4523 PF15023.6 KDO19447.1 - 0.02 14.7 0.0 2 8.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4523) Peripla_BP_4 PF13407.6 KDO19447.1 - 0.088 12.4 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain RRM_2 PF04059.12 KDO19447.1 - 0.1 12.8 0.0 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif 2 TC1 PF15063.6 KDO19447.1 - 0.12 12.2 0.0 7.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Thyroid cancer protein 1 RRM_occluded PF16842.5 KDO19447.1 - 0.14 12.1 0.0 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif OB_RNB PF08206.11 KDO19447.1 - 0.46 10.2 1.8 37 4.1 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain Dynactin_p62 PF05502.13 KDO19448.1 - 1.7e-07 30.4 9.3 0.00077 18.4 6.7 2.8 1 1 1 2 2 2 2 Dynactin p62 family zinc-ribbons_6 PF07191.12 KDO19448.1 - 0.0089 16.0 1.1 0.0089 16.0 1.1 2.4 1 1 1 2 2 2 1 zinc-ribbons HscB_4_cys PF18256.1 KDO19448.1 - 4.6 7.1 7.0 0.62 9.9 0.1 3.0 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif MCM PF00493.23 KDO19449.1 - 7.8e-104 345.7 0.1 1.3e-103 345.0 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KDO19449.1 - 8.5e-36 122.6 0.1 1.6e-35 121.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KDO19449.1 - 2.9e-25 88.5 2.9 2.9e-25 88.5 2.9 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 KDO19449.1 - 2.9e-19 69.3 0.1 1.6e-18 66.9 0.1 2.3 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 KDO19449.1 - 5e-10 39.1 0.0 3.4e-08 33.1 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KDO19449.1 - 1.3e-06 28.9 0.5 3.2e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KDO19449.1 - 0.00012 22.1 0.0 0.00046 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 KDO19449.1 - 0.0012 19.4 1.3 0.14 12.8 0.4 3.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 KDO19449.1 - 0.0013 18.5 0.0 0.0061 16.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KDO19449.1 - 0.0019 18.0 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FYVE PF01363.21 KDO19451.1 - 8.2e-17 61.1 8.0 2e-16 59.8 8.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KDO19451.1 - 6.9e-08 32.9 0.0 1.2e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 PH domain ACBP PF00887.19 KDO19451.1 - 2.7e-06 27.5 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein FYVE_2 PF02318.16 KDO19451.1 - 0.002 18.3 4.0 0.0043 17.3 4.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger cEGF PF12662.7 KDO19451.1 - 0.34 10.9 3.5 0.72 9.8 3.5 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like zinc_ribbon_12 PF11331.8 KDO19451.1 - 5.3 6.9 9.9 46 3.9 0.1 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain COPI_assoc PF08507.10 KDO19452.1 - 7.2e-15 55.2 9.0 9.2e-15 54.9 9.0 1.2 1 0 0 1 1 1 1 COPI associated protein EnY2 PF10163.9 KDO19453.1 - 2.7e-33 114.2 0.5 3.4e-33 113.8 0.5 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Importin_rep_6 PF18829.1 KDO19453.1 - 0.045 13.9 0.1 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Importin repeat 6 DUF4090 PF13319.6 KDO19453.1 - 0.046 14.0 0.1 0.088 13.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4090) DUF668 PF05003.12 KDO19453.1 - 0.078 13.4 0.4 0.79 10.2 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF668) HHH_9 PF17674.1 KDO19453.1 - 0.86 10.5 3.2 17 6.4 3.2 2.1 1 1 0 1 1 1 0 HHH domain TPR_19 PF14559.6 KDO19454.1 - 7.5e-11 42.4 19.9 3.3e-06 27.5 0.5 6.5 6 2 2 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO19454.1 - 4.8e-07 29.9 26.2 0.0098 16.1 0.8 5.8 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KDO19454.1 - 2.4e-06 27.2 25.1 0.12 12.5 0.2 7.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO19454.1 - 6.1e-06 26.6 18.3 0.0037 18.0 1.9 6.8 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO19454.1 - 2.7e-05 24.7 13.2 0.0019 18.8 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO19454.1 - 7.8e-05 22.7 6.1 0.019 15.1 0.3 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO19454.1 - 0.002 18.0 6.9 5.1 7.4 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO19454.1 - 0.0022 18.3 19.5 0.023 15.0 2.7 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO19454.1 - 0.015 15.3 5.1 0.7 10.0 0.5 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 KDO19454.1 - 0.016 14.8 5.0 11 5.7 0.1 4.9 3 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 KDO19454.1 - 0.018 14.5 5.3 0.042 13.3 1.7 2.9 3 1 1 4 4 4 0 Coatomer epsilon subunit SRP_TPR_like PF17004.5 KDO19454.1 - 0.032 14.3 7.6 0.036 14.1 0.3 3.4 4 0 0 4 4 4 0 Putative TPR-like repeat TPR_8 PF13181.6 KDO19454.1 - 0.034 14.3 9.7 1.9 8.9 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19454.1 - 3.1 7.8 25.8 0.16 11.8 0.4 7.3 7 1 1 8 8 8 0 Tetratricopeptide repeat P63C PF10546.9 KDO19455.1 - 0.013 16.0 0.2 49 4.6 0.0 4.6 6 0 0 6 6 6 0 P63C domain Uso1_p115_head PF04869.14 KDO19456.1 - 0.017 14.3 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region NanE PF04131.14 KDO19456.1 - 0.049 12.8 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PUF PF00806.19 KDO19457.1 - 2.7e-45 149.6 0.3 1.9e-05 24.1 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH_4 PF18044.1 KDO19457.1 - 4e-07 29.7 4.8 1e-06 28.4 4.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KDO19457.1 - 4.2e-06 27.4 0.1 9.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 KDO19457.1 - 0.00011 22.0 4.6 0.00022 21.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO19457.1 - 0.00019 21.4 7.8 0.00036 20.5 7.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KDO19457.1 - 0.029 14.8 5.1 0.057 13.9 5.1 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger AAA_lid_4 PF17864.1 KDO19457.1 - 0.6 9.9 1.8 29 4.5 0.0 3.0 3 0 0 3 3 3 0 RuvB AAA lid domain FHA PF00498.26 KDO19458.1 - 3.2e-15 56.2 0.0 6.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO19458.1 - 1.3e-07 31.8 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SMN PF06003.12 KDO19458.1 - 0.0087 15.3 1.2 0.015 14.6 1.2 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Glucan_synthase PF02364.15 KDO19459.1 - 3.8e-186 620.8 13.4 1.5e-166 556.0 9.9 2.2 1 1 1 2 2 2 2 1,3-beta-glucan synthase component Sugar_tr PF00083.24 KDO19459.1 - 2.1e-24 86.2 30.9 5e-24 85.0 30.9 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter FKS1_dom1 PF14288.6 KDO19459.1 - 6.2e-24 84.8 4.5 1.8e-23 83.3 3.2 2.5 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RNA_lig_T4_1 PF09511.10 KDO19460.1 - 0.0052 16.7 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DUF4823 PF16105.5 KDO19460.1 - 0.024 14.5 0.3 0.44 10.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4823) SSL_OB PF09199.10 KDO19460.1 - 0.092 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain Ank_2 PF12796.7 KDO19461.1 - 7.3e-11 42.5 5.3 0.00061 20.3 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO19461.1 - 2.9e-09 37.0 6.2 0.55 10.6 0.2 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO19461.1 - 4.2e-07 30.4 10.9 0.031 14.9 0.2 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19461.1 - 3.2e-06 27.0 1.5 4 8.3 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Phage_int_SAM_1 PF02899.17 KDO19461.1 - 0.03 14.6 0.3 1.8 8.9 0.0 3.3 2 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Ank PF00023.30 KDO19461.1 - 0.053 14.0 1.4 14 6.4 0.0 4.3 3 2 0 3 3 3 0 Ankyrin repeat Cuticle_4 PF15955.5 KDO19461.1 - 0.53 11.0 5.5 0.12 13.1 1.3 2.1 2 1 0 2 2 2 0 Cuticle protein DUF4690 PF15756.5 KDO19462.1 - 0.0015 19.1 2.4 0.0022 18.5 2.4 1.4 1 1 0 1 1 1 1 Small Novel Rich in Cartilage YjbE PF11106.8 KDO19462.1 - 2 8.7 14.6 5.2 7.4 14.6 1.6 1 1 0 1 1 1 0 Exopolysaccharide production protein YjbE DUF2613 PF11021.8 KDO19462.1 - 2.2 8.5 7.2 0.32 11.1 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) CLASP_N PF12348.8 KDO19463.1 - 5.4e-06 26.1 0.1 6.5e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 CLASP N terminal SLC12 PF03522.15 KDO19464.1 - 2.6e-09 36.6 0.0 2.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Solute carrier family 12 Retrotran_gag_2 PF14223.6 KDO19464.1 - 0.05 13.3 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NMT1_2 PF13379.6 KDO19464.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family LRR_6 PF13516.6 KDO19467.1 - 1.6e-07 30.8 2.8 0.65 10.2 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeat PX PF00787.24 KDO19472.1 - 4.3e-05 23.5 0.0 8.4e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 PX domain DUF1390 PF07150.11 KDO19472.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF3024 PF11225.8 KDO19472.1 - 0.19 12.0 0.0 0.86 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) PIP5K PF01504.18 KDO19473.1 - 2.6e-60 204.0 3.1 9.8e-52 175.9 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Adeno_E3B PF03376.14 KDO19473.1 - 0.0073 16.5 0.9 0.022 15.0 0.9 1.7 1 0 0 1 1 1 1 Adenovirus E3B protein RCR PF12273.8 KDO19473.1 - 0.92 10.2 2.5 1 10.1 1.0 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DHHC PF01529.20 KDO19473.1 - 1.8 8.6 5.3 7 6.8 5.3 2.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase FixH PF05751.11 KDO19473.1 - 4.1 7.4 7.7 0.77 9.8 1.6 2.3 2 0 0 2 2 2 0 FixH CaMKII_AD PF08332.10 KDO19474.1 - 1.3e-23 83.5 0.2 2.6e-23 82.6 0.2 1.5 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain ADK PF00406.22 KDO19474.1 - 5.6e-14 52.5 0.0 9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KDO19474.1 - 1.2e-09 38.7 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF4440 PF14534.6 KDO19474.1 - 1.8e-07 31.5 0.0 3.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KDO19474.1 - 1.8e-06 28.2 0.3 2.2e-05 24.7 0.2 2.4 3 0 0 3 3 3 1 SnoaL-like domain DUF5492 PF17596.2 KDO19474.1 - 0.13 12.6 0.1 0.34 11.3 0.1 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5492) Lamprin PF06403.11 KDO19474.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Lamprin Kelch_3 PF13415.6 KDO19475.1 - 1.4e-14 53.9 2.1 0.0012 19.1 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO19475.1 - 6.2e-11 42.0 0.0 0.36 10.9 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KDO19475.1 - 9.5e-09 35.1 0.4 0.012 15.6 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO19475.1 - 0.056 13.0 0.0 2.4 7.8 0.0 3.4 4 0 0 4 4 4 0 Kelch motif PRIMA1 PF16101.5 KDO19476.1 - 8.1e-05 22.6 0.3 8.1e-05 22.6 0.3 2.2 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 Mid2 PF04478.12 KDO19476.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KDO19476.1 - 0.013 15.5 1.0 0.033 14.1 1.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family SRTM1 PF15872.5 KDO19476.1 - 0.038 14.2 0.2 0.099 12.8 0.2 1.7 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Cation_ATPase_C PF00689.21 KDO19476.1 - 0.078 12.7 1.0 4.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus OAD_gamma PF04277.13 KDO19476.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MtrF PF09472.10 KDO19476.1 - 1.8 8.0 7.9 4.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3021 PF11457.8 KDO19476.1 - 3.2 8.1 6.1 0.46 10.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Pox_D3 PF04580.13 KDO19477.1 - 0.087 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein BRX PF08381.11 KDO19477.1 - 0.1 12.0 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 LRR_6 PF13516.6 KDO19478.1 - 0.0003 20.6 2.1 0.0044 16.9 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeat DUF420 PF04238.12 KDO19484.1 - 0.078 13.3 2.4 3.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF420) BT1 PF03092.16 KDO19486.1 - 1.4e-14 53.3 11.4 2.4e-14 52.5 0.7 2.4 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO19486.1 - 1.1e-09 37.7 23.4 1.1e-09 37.7 23.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SET PF00856.28 KDO19489.1 - 0.012 16.0 0.3 0.041 14.3 0.3 1.9 1 1 0 1 1 1 0 SET domain DUF4054 PF13262.6 KDO19490.1 - 0.1 12.6 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Peptidase_C1 PF00112.23 KDO19493.1 - 3.1e-53 181.1 9.5 3.1e-53 181.1 9.5 1.6 2 0 0 2 2 2 1 Papain family cysteine protease PT PF04886.12 KDO19493.1 - 0.024 14.2 59.8 4.1e+02 0.6 18.9 4.4 1 1 1 2 2 2 0 PT repeat Peptidase_C1_2 PF03051.15 KDO19493.1 - 0.09 11.5 2.0 0.36 9.5 0.3 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Inhibitor_I29 PF08246.12 KDO19493.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Pkinase PF00069.25 KDO19494.1 - 5.5e-52 176.7 0.0 7.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19494.1 - 6.9e-51 173.0 0.0 9.1e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO19494.1 - 0.0018 17.2 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO19494.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4444 PF14563.6 KDO19494.1 - 0.025 14.2 0.1 0.071 12.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) APH PF01636.23 KDO19494.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C1 PF00112.23 KDO19496.1 - 1.4e-50 172.4 3.3 1.7e-50 172.2 3.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO19496.1 - 0.0015 17.4 0.1 0.047 12.4 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family SlpA PF03217.14 KDO19496.1 - 0.019 15.6 2.3 0.5 11.0 0.2 2.4 2 0 0 2 2 2 0 Surface later protein A domain Ank_2 PF12796.7 KDO19497.1 - 3e-08 34.1 10.6 0.012 16.2 0.2 4.6 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19497.1 - 1.4e-05 25.6 9.8 0.41 11.3 0.1 5.8 3 3 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19497.1 - 0.001 19.3 13.1 0.99 9.8 0.0 6.2 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19497.1 - 0.3 11.8 10.0 76 4.4 0.1 7.0 6 2 2 8 8 8 0 Ankyrin repeat Pkinase PF00069.25 KDO19500.1 - 3.5e-52 177.4 0.0 5.7e-52 176.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19500.1 - 5.8e-24 84.8 0.0 7.6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO19500.1 - 3.4e-07 30.4 3.5 0.0023 17.9 0.4 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO19500.1 - 2.8e-05 23.6 0.0 5.5e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO19500.1 - 0.0023 16.8 0.0 0.0053 15.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KDO19500.1 - 0.0035 16.9 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KDO19500.1 - 0.046 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_11 PF16859.5 KDO19500.1 - 0.27 11.6 6.4 1.6 9.1 0.1 3.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pox_ser-thr_kin PF05445.11 KDO19500.1 - 0.33 9.9 0.0 0.47 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IncD PF17628.2 KDO19503.1 - 0.59 9.9 4.2 5.8 6.7 1.8 2.2 2 0 0 2 2 2 0 Inclusion membrane protein D DUF4203 PF13886.6 KDO19505.1 - 4.5e-10 39.5 14.3 6.4e-10 39.0 14.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Peptidase_C47 PF05543.13 KDO19505.1 - 0.081 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Staphopain peptidase C47 UPF0047 PF01894.17 KDO19505.1 - 0.2 11.8 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 DUF2374 PF09574.10 KDO19505.1 - 0.74 9.7 9.2 0.075 12.9 3.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (Duf2374) DUF2613 PF11021.8 KDO19505.1 - 1.7 8.8 5.9 18 5.5 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF4203 PF13886.6 KDO19506.1 - 6.5e-40 137.0 33.8 7.7e-40 136.7 33.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Robl_LC7 PF03259.17 KDO19511.1 - 2.5e-05 24.0 0.3 0.0016 18.1 0.3 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain PRKCSH-like PF12999.7 KDO19512.1 - 3.9e-34 118.0 1.2 3.9e-34 118.0 1.2 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KDO19512.1 - 8.2e-30 103.5 0.2 1.8e-29 102.4 0.0 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KDO19512.1 - 0.0047 16.8 0.1 0.0047 16.8 0.1 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 PRKCSH PF07915.13 KDO19512.1 - 0.0091 17.0 0.1 0.024 15.6 0.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 KDO19512.1 - 1.1 9.6 17.5 4.1 7.7 6.0 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Extensin_2 PF04554.13 KDO19513.1 - 0.42 10.7 32.4 16 5.7 27.3 2.4 1 1 1 2 2 2 0 Extensin-like region ATP-synt PF00231.19 KDO19514.1 - 2e-73 247.6 2.5 2.3e-73 247.4 2.5 1.0 1 0 0 1 1 1 1 ATP synthase THOC7 PF05615.13 KDO19514.1 - 0.25 11.6 2.4 2.1 8.6 2.3 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 TPR_2 PF07719.17 KDO19515.1 - 1.4e-08 34.2 5.0 0.016 15.3 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19515.1 - 2.4e-07 30.3 1.4 0.49 10.3 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Arm PF00514.23 KDO19515.1 - 0.0004 20.3 2.8 2.7 8.2 0.0 4.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat TPR_14 PF13428.6 KDO19515.1 - 0.00057 20.5 18.0 0.047 14.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO19515.1 - 0.0075 16.5 1.1 0.0075 16.5 1.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO19515.1 - 0.026 14.7 1.2 1.8 9.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 KDO19515.1 - 0.3 11.5 3.0 5.6 7.5 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat TPR_9 PF13371.6 KDO19515.1 - 0.31 11.2 20.5 0.05 13.8 1.3 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO19515.1 - 0.52 10.0 4.2 5.6 6.7 0.1 2.9 3 0 0 3 3 3 0 TPR repeat Fis1_TPR_C PF14853.6 KDO19515.1 - 6.6 6.9 12.1 0.092 12.8 0.7 3.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Tctex-1 PF03645.13 KDO19516.1 - 2e-26 92.2 0.2 2.3e-26 92.0 0.2 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 KDO19516.1 - 0.061 12.9 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family PhoLip_ATPase_C PF16212.5 KDO19518.1 - 5e-63 213.2 18.2 5e-63 213.2 18.2 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO19518.1 - 1.6e-18 66.1 0.3 4.4e-18 64.7 0.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO19518.1 - 1.1e-12 48.7 0.1 1.3e-06 28.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO19518.1 - 3.1e-11 43.2 0.0 1.1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO19518.1 - 1.6e-09 37.5 0.2 1.6e-09 37.5 0.2 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO19518.1 - 0.0073 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ibs_toxin PF13956.6 KDO19518.1 - 0.058 13.4 1.1 0.22 11.6 1.1 2.0 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system PAN_4 PF14295.6 KDO19519.1 - 1.9e-24 85.3 43.5 3.4e-09 36.5 4.9 4.4 5 0 0 5 5 5 3 PAN domain Tyrosinase PF00264.20 KDO19519.1 - 5.2e-23 82.5 3.3 3.3e-11 43.9 0.2 2.6 1 1 1 2 2 2 2 Common central domain of tyrosinase PAN_1 PF00024.26 KDO19519.1 - 3.8e-16 58.8 9.2 7.7e-05 22.6 0.4 3.7 1 1 2 3 3 3 3 PAN domain CAP_N PF01213.19 KDO19519.1 - 0.015 14.8 0.4 0.029 13.9 0.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MANEC PF07502.14 KDO19519.1 - 0.024 14.9 17.0 2.6 8.4 0.4 4.6 4 0 0 4 4 4 0 MANEC domain PAN_3 PF08277.12 KDO19519.1 - 10 6.0 18.0 6.3 6.7 1.2 3.7 3 0 0 3 3 3 0 PAN-like domain Tyrosinase PF00264.20 KDO19520.1 - 1.1e-21 78.2 3.9 5.2e-11 43.3 0.5 2.5 1 1 1 2 2 2 2 Common central domain of tyrosinase PT PF04886.12 KDO19520.1 - 1.5e-12 46.8 93.7 0.0001 21.8 25.0 4.7 1 1 2 3 3 3 3 PT repeat PAN_4 PF14295.6 KDO19520.1 - 1.9e-06 27.7 17.7 0.0005 19.9 3.8 3.1 3 0 0 3 3 3 2 PAN domain ZirS_C PF16583.5 KDO19520.1 - 0.018 14.6 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Pkinase PF00069.25 KDO19522.1 - 5.3e-47 160.4 0.0 7.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19522.1 - 8.3e-46 156.4 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO19522.1 - 0.0008 18.3 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO19522.1 - 0.0095 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain TMEM154 PF15102.6 KDO19522.1 - 0.54 10.2 4.4 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family SDF PF00375.18 KDO19524.1 - 2e-20 73.2 1.1 2.3e-20 73.0 1.1 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2070 PF09843.9 KDO19524.1 - 0.012 14.0 0.9 0.015 13.6 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RdRP PF05183.12 KDO19525.1 - 5.9e-144 480.9 0.0 7.6e-144 480.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase VIT PF08487.10 KDO19525.1 - 0.0029 17.8 0.2 0.006 16.8 0.2 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain LEA_4 PF02987.16 KDO19526.1 - 2.1e-13 50.1 35.0 3.4e-07 30.2 5.9 2.7 1 1 2 3 3 3 3 Late embryogenesis abundant protein Apolipoprotein PF01442.18 KDO19526.1 - 2e-05 24.6 5.0 7.6e-05 22.7 5.1 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KDO19526.1 - 2.4e-05 24.8 11.5 0.0001 22.8 11.5 1.9 1 1 0 1 1 1 1 YtxH-like protein DUF883 PF05957.13 KDO19526.1 - 0.00028 21.4 9.6 0.0013 19.3 9.2 1.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.11 KDO19526.1 - 0.062 13.4 1.9 0.067 13.3 1.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MT0933_antitox PF14013.6 KDO19526.1 - 0.11 12.9 16.9 2.1 8.7 10.9 2.5 1 1 1 2 2 2 0 MT0933-like antitoxin protein Phasin PF05597.11 KDO19526.1 - 0.11 12.5 8.1 1.5 8.8 1.8 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3810 PF12725.7 KDO19526.1 - 0.13 11.5 1.3 0.15 11.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Oleosin PF01277.17 KDO19526.1 - 0.35 10.6 5.7 1.7 8.4 0.3 2.1 1 1 1 2 2 2 0 Oleosin ATP-synt_B PF00430.18 KDO19526.1 - 0.35 11.0 5.7 0.47 10.6 5.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CENP-H PF05837.12 KDO19526.1 - 0.43 11.0 6.2 0.54 10.7 6.2 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1771 PF08590.10 KDO19526.1 - 2.6 8.5 8.9 8.5 6.8 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1771) TMPIT PF07851.13 KDO19526.1 - 4.5 6.4 4.6 4.8 6.3 4.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein LEA_4 PF02987.16 KDO19527.1 - 4e-10 39.6 26.6 5.3e-06 26.4 4.8 2.3 1 1 1 2 2 2 2 Late embryogenesis abundant protein YtxH PF12732.7 KDO19527.1 - 1.7e-05 25.2 7.3 2.4e-05 24.8 7.3 1.4 1 0 0 1 1 1 1 YtxH-like protein DUF883 PF05957.13 KDO19527.1 - 8.5e-05 23.1 6.3 0.0001 22.8 6.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KDO19527.1 - 0.00025 21.0 3.4 0.002 18.0 1.3 1.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain CdvA PF18822.1 KDO19527.1 - 0.006 16.4 2.3 0.0078 16.0 2.3 1.1 1 0 0 1 1 1 1 CdvA-like coiled-coil domain DUF1771 PF08590.10 KDO19527.1 - 0.057 13.8 4.9 0.085 13.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) MT0933_antitox PF14013.6 KDO19527.1 - 0.13 12.6 13.8 0.13 12.6 7.0 2.3 1 1 1 2 2 2 0 MT0933-like antitoxin protein ATP-synt_B PF00430.18 KDO19527.1 - 0.2 11.7 5.2 0.24 11.5 5.2 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Phasin PF05597.11 KDO19527.1 - 0.36 10.8 5.5 1.1 9.3 3.3 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3810 PF12725.7 KDO19527.1 - 0.46 9.8 1.8 0.52 9.6 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ISG65-75 PF11727.8 KDO19527.1 - 0.59 9.3 11.3 0.61 9.3 11.3 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Oleosin PF01277.17 KDO19527.1 - 1.7 8.4 4.5 5.9 6.7 1.1 2.0 1 1 1 2 2 2 0 Oleosin RdRP PF05183.12 KDO19528.1 - 1.1e-148 496.5 0.0 1.3e-148 496.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Vps62 PF06101.11 KDO19530.1 - 0.11 10.8 0.1 4.8 5.4 0.0 2.1 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 62 DUF4404 PF14357.6 KDO19530.1 - 0.4 11.3 2.5 24 5.7 0.5 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) Syntaxin_2 PF14523.6 KDO19530.1 - 0.91 9.9 3.0 2.1 8.8 0.1 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF883 PF05957.13 KDO19531.1 - 0.029 15.0 0.4 0.12 13.0 0.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Vps62 PF06101.11 KDO19532.1 - 0.00066 18.1 0.2 0.042 12.2 0.1 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 62 Vps62 PF06101.11 KDO19533.1 - 0.0016 16.8 0.2 0.018 13.4 0.1 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 62 DIM PF08194.12 KDO19534.1 - 0.0029 17.8 0.7 0.0079 16.4 0.7 1.8 1 0 0 1 1 1 1 DIM protein Vps62 PF06101.11 KDO19534.1 - 0.02 13.2 0.3 0.26 9.6 0.1 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 62 Pkinase_Tyr PF07714.17 KDO19535.1 - 5.4e-36 124.2 0.0 7.6e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19535.1 - 2.3e-29 102.6 0.0 2.8e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-RVT PF13966.6 KDO19535.1 - 0.0067 17.1 1.2 0.0067 17.1 1.2 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Ank_2 PF12796.7 KDO19536.1 - 1.2e-64 214.9 0.2 3.2e-14 53.3 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO19536.1 - 2.4e-48 161.6 15.9 2e-09 37.5 0.0 9.7 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO19536.1 - 2.8e-44 148.9 1.6 4.7e-08 33.4 0.0 8.6 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19536.1 - 5.3e-43 140.1 10.6 0.0022 18.3 0.0 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 KDO19536.1 - 3e-33 112.8 24.6 0.0019 18.6 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat LicD PF04991.13 KDO19537.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 LicD family DUF1010 PF06231.11 KDO19537.1 - 0.025 15.1 0.1 0.11 13.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) LicD PF04991.13 KDO19538.1 - 0.0002 21.6 1.1 0.00027 21.1 0.0 1.7 2 0 0 2 2 2 1 LicD family Elicitin PF00964.17 KDO19539.1 - 0.015 15.4 4.8 0.015 15.4 4.8 3.9 3 1 1 4 4 4 0 Elicitin FeS PF04060.13 KDO19539.1 - 0.12 12.0 1.4 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 Putative Fe-S cluster PT PF04886.12 KDO19539.1 - 1.2 8.7 18.4 3.1 7.4 18.4 1.7 1 0 0 1 1 1 0 PT repeat DUF281 PF03436.13 KDO19539.1 - 5.2 7.5 7.9 3.7 8.0 3.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF281) Choline_transpo PF04515.12 KDO19541.1 - 3.3e-14 52.8 10.2 1e-11 44.6 8.9 2.9 1 1 1 2 2 2 2 Plasma-membrane choline transporter DUF5400 PF17379.2 KDO19541.1 - 0.21 12.1 5.6 0.071 13.6 2.9 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5400) DUF3573 PF12097.8 KDO19542.1 - 0.058 12.2 1.1 0.087 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) bZIP_2 PF07716.15 KDO19542.1 - 0.18 11.9 8.1 0.45 10.6 8.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper EBP50_C PF09007.11 KDO19542.1 - 1.9 9.5 12.8 0.61 11.1 8.2 2.3 3 0 0 3 3 3 0 EBP50, C-terminal TolA_bind_tri PF16331.5 KDO19542.1 - 3.7 7.7 10.7 14 5.8 5.2 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation Pkinase_Tyr PF07714.17 KDO19543.1 - 4e-58 196.7 0.0 8.4e-44 149.8 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KDO19543.1 - 8.4e-51 172.9 0.0 2.3e-43 148.5 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain C2 PF00168.30 KDO19543.1 - 2.4e-09 37.4 0.0 4.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kdo PF06293.14 KDO19543.1 - 1.9e-08 33.9 0.9 0.0015 17.9 0.5 2.6 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO19543.1 - 1e-05 25.0 0.6 0.1 11.9 0.1 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO19543.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO19543.1 - 0.034 14.1 2.9 0.26 11.2 0.5 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family MBOAT PF03062.19 KDO19544.1 - 9.9e-37 127.1 7.5 2.1e-36 126.0 7.5 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF2198 PF09964.9 KDO19544.1 - 6 7.0 7.3 0.23 11.6 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Pkinase PF00069.25 KDO19548.1 - 1.2e-38 133.0 0.0 1.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19548.1 - 9.3e-14 51.3 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO19548.1 - 6.5e-05 22.4 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO19548.1 - 0.00044 20.2 0.9 0.0027 17.7 0.8 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO19548.1 - 0.0008 19.0 0.0 0.008 15.7 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KDO19548.1 - 0.0032 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 KDO19548.1 - 0.054 14.0 0.2 0.13 12.8 0.2 1.7 1 1 0 1 1 1 0 PH domain V_ATPase_I PF01496.19 KDO19549.1 - 5.8 4.7 5.2 9.7 4.0 5.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec7 PF01369.20 KDO19550.1 - 6.8e-60 201.9 0.0 1.5e-59 200.8 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KDO19550.1 - 6.9e-23 81.3 4.0 6.9e-23 81.3 4.0 2.2 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KDO19550.1 - 2.2e-05 24.2 0.1 5.5e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Thioredoxin PF00085.20 KDO19551.1 - 2.8e-18 65.8 0.0 3.4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO19551.1 - 0.00022 21.7 0.2 0.004 17.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KDO19551.1 - 0.071 12.9 0.0 0.095 12.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 KDO19551.1 - 0.081 13.3 0.0 0.24 11.7 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin-like CCDC53 PF10152.9 KDO19557.1 - 2.8e-06 27.8 0.5 7e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex BAR PF03114.18 KDO19557.1 - 0.0001 22.1 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 BAR domain Pkinase PF00069.25 KDO19558.1 - 2.9e-34 118.6 0.0 4e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19558.1 - 1.3e-31 109.9 0.0 2.3e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO19558.1 - 4.7e-05 22.8 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L12 PF00542.19 KDO19560.1 - 5.6e-23 81.1 8.2 5.6e-23 81.1 8.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KDO19560.1 - 0.0045 16.7 3.2 0.0045 16.7 3.2 3.3 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain Pkinase PF00069.25 KDO19561.1 - 3.9e-37 128.0 0.0 2.4e-35 122.2 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19561.1 - 4.5e-35 121.2 0.0 1.5e-33 116.2 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase DUF2207 PF09972.9 KDO19561.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) S1FA PF04689.13 KDO19561.1 - 0.066 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA APH PF01636.23 KDO19561.1 - 0.089 12.7 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19561.1 - 0.18 10.7 0.0 3.1 6.7 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Beta-APP PF03494.13 KDO19561.1 - 0.2 11.5 3.4 0.38 10.6 3.4 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) LRR_4 PF12799.7 KDO19562.1 - 8.9e-06 26.0 9.3 0.00048 20.5 3.9 2.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19562.1 - 1.3e-05 24.9 0.4 3.6e-05 23.4 0.2 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 KDO19562.1 - 0.00028 21.0 2.0 0.095 13.3 0.1 3.0 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO19562.1 - 0.065 13.3 0.0 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat BT1 PF03092.16 KDO19564.1 - 2.2e-18 65.8 16.5 3.9e-17 61.7 4.5 2.3 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO19564.1 - 7.2e-10 38.3 34.1 7.2e-10 38.3 34.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M13_N PF05649.13 KDO19565.1 - 4.1e-54 184.7 0.0 6.5e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO19565.1 - 7.9e-46 156.2 0.1 9.9e-45 152.7 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M13 PTH2 PF01981.16 KDO19566.1 - 6.6e-46 155.4 0.6 6.6e-46 155.4 0.6 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 FAM176 PF14851.6 KDO19566.1 - 8 6.1 6.4 21 4.7 6.4 1.7 1 1 0 1 1 1 0 FAM176 family FH2 PF02181.23 KDO19567.1 - 0.058 12.5 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain HAUS-augmin3 PF14932.6 KDO19567.1 - 0.063 12.9 1.9 0.085 12.4 0.7 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TipAS PF07739.13 KDO19567.1 - 0.25 11.9 3.0 0.4 11.2 2.9 1.6 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Tup_N PF08581.10 KDO19567.1 - 0.67 10.3 3.6 4 7.8 0.6 2.6 2 1 0 2 2 2 0 Tup N-terminal DUF974 PF06159.13 KDO19568.1 - 2.8e-53 181.3 0.0 8.6e-53 179.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 KDO19568.1 - 3.2e-06 26.8 1.8 0.094 12.1 0.2 3.1 2 1 1 3 3 3 3 TRAPP trafficking subunit Trs65 Yop-YscD_cpl PF16697.5 KDO19569.1 - 6e-06 26.5 0.0 0.05 13.9 0.0 2.4 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KDO19569.1 - 6.3e-06 26.5 0.0 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 2 FHA domain BT1 PF03092.16 KDO19570.1 - 5.2e-17 61.3 3.1 7.4e-17 60.8 3.1 1.2 1 0 0 1 1 1 1 BT1 family cNMP_binding PF00027.29 KDO19570.1 - 2.8e-13 49.8 0.0 8.3e-12 45.0 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Yop-YscD_cpl PF16697.5 KDO19570.1 - 3.9e-09 36.7 0.0 9.2e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KDO19570.1 - 3.8e-06 27.1 0.0 9.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain PUCC PF03209.15 KDO19570.1 - 0.00013 21.1 2.5 0.00013 21.1 2.5 1.7 1 1 1 2 2 2 1 PUCC protein RTC PF01137.21 KDO19571.1 - 2.3e-60 203.6 0.9 3.1e-60 203.1 0.9 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TatD_DNase PF01026.21 KDO19571.1 - 4.5e-59 199.9 0.0 7.6e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase EF-hand_7 PF13499.6 KDO19572.1 - 1.3e-11 44.8 0.0 2.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO19572.1 - 3.2e-11 41.9 0.0 5.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO19572.1 - 1.2e-09 37.4 0.0 0.0005 19.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain IQ PF00612.27 KDO19572.1 - 4.6e-09 35.3 22.3 0.0082 15.9 0.3 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif EF-hand_5 PF13202.6 KDO19572.1 - 1.5e-08 33.7 0.0 0.0081 15.6 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO19572.1 - 5.4e-07 29.4 0.0 0.00033 20.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair Ly49 PF08391.10 KDO19572.1 - 4 7.8 6.9 0.64 10.4 2.5 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region zf-CCCH PF00642.24 KDO19574.1 - 2.3e-08 33.8 14.3 7.4e-08 32.1 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO19574.1 - 2.1e-07 30.6 17.6 6e-06 25.9 4.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger CTD_bind PF04818.13 KDO19574.1 - 5.7e-07 30.3 0.0 1.1e-06 29.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_CCCH_4 PF18345.1 KDO19574.1 - 1.9e-06 27.7 18.9 4e-05 23.5 3.7 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KDO19574.1 - 1.4e-05 25.7 7.5 0.012 16.3 1.3 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KDO19574.1 - 0.0023 18.2 1.5 0.2 11.9 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KDO19574.1 - 0.017 15.6 12.5 0.032 14.7 2.8 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger CDO_I PF05995.12 KDO19575.1 - 1e-29 103.0 0.0 1.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KDO19575.1 - 0.0023 17.4 0.3 0.013 15.0 0.3 2.0 1 1 0 1 1 1 1 PCO_ADO Metallophos PF00149.28 KDO19576.1 - 3.9e-12 47.1 0.2 8.6e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO19576.1 - 0.00044 20.5 0.0 0.001 19.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDO_I PF05995.12 KDO19577.1 - 4.4e-32 110.7 0.0 4.9e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KDO19577.1 - 7.2e-05 22.3 0.1 0.00061 19.3 0.1 2.1 1 1 0 1 1 1 1 PCO_ADO DOT1 PF08123.13 KDO19578.1 - 1.3e-16 60.7 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KDO19578.1 - 0.14 12.0 0.2 0.45 10.3 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pro_isomerase PF00160.21 KDO19579.1 - 2.3e-47 161.2 0.1 4e-47 160.4 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CDC45 PF02724.14 KDO19579.1 - 0.0045 15.3 15.8 0.005 15.2 15.8 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF936 PF06075.12 KDO19579.1 - 0.24 10.2 18.8 0.27 10.1 18.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Rtf2 PF04641.12 KDO19579.1 - 2 7.7 13.6 3 7.2 13.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger API5 PF05918.11 KDO19579.1 - 2.8 6.6 9.7 3.9 6.2 9.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RR_TM4-6 PF06459.12 KDO19579.1 - 7.6 6.3 9.5 11 5.7 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SBP_bac_6 PF13343.6 KDO19580.1 - 8.5e-16 58.1 1.7 2.8e-15 56.4 1.7 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KDO19580.1 - 2.6e-06 27.6 10.9 1e-05 25.7 10.9 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KDO19580.1 - 0.00023 21.0 0.3 0.0049 16.6 0.0 2.4 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein Nup160 PF11715.8 KDO19581.1 - 1.8e-09 36.8 0.0 4.2e-09 35.6 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ank_2 PF12796.7 KDO19582.1 - 1.1e-60 202.2 29.3 1.6e-18 67.1 0.0 8.4 2 1 10 12 12 12 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19582.1 - 3.9e-39 132.5 4.9 1.1e-09 38.7 0.1 8.3 6 1 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19582.1 - 1.4e-37 127.2 17.1 5.8e-09 36.1 0.2 10.5 5 3 6 12 12 12 7 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO19582.1 - 6e-35 120.9 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KDO19582.1 - 1.5e-34 114.1 10.0 0.00011 22.3 0.0 13.3 13 0 0 13 13 13 6 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO19582.1 - 2.3e-33 115.6 0.0 3.7e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KDO19582.1 - 6.2e-30 102.3 19.6 0.00011 22.4 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat Kinase-like PF14531.6 KDO19582.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Big_10 PF17964.1 KDO19582.1 - 0.16 11.9 0.1 23 4.9 0.0 2.8 2 0 0 2 2 2 0 Bacterial Ig domain Alpha_kinase PF02816.18 KDO19583.1 - 6.6e-44 150.2 0.0 9.4e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Stc1 PF12898.7 KDO19583.1 - 0.014 16.0 1.6 0.014 16.0 1.6 2.3 1 1 1 2 2 2 0 Stc1 domain zf-trcl PF13451.6 KDO19583.1 - 0.066 13.1 1.0 0.066 13.1 1.0 2.8 2 2 0 2 2 2 0 Probable zinc-ribbon domain MCR PF18509.1 KDO19583.1 - 0.083 12.5 2.6 0.37 10.4 2.6 2.2 1 0 0 1 1 1 0 Magnetochrome domain Zn-ribbon_8 PF09723.10 KDO19583.1 - 0.15 12.2 4.2 6.3 7.0 0.4 2.7 2 1 1 3 3 3 0 Zinc ribbon domain Prok-RING_1 PF14446.6 KDO19583.1 - 0.34 10.9 5.6 0.24 11.4 0.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 KDO19583.1 - 1.3 9.5 4.8 3.4 8.1 3.3 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Alpha_kinase PF02816.18 KDO19584.1 - 1.3e-44 152.5 0.0 2.1e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KDO19584.1 - 1.7e-06 28.6 0.0 3.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain OST-HTH PF12872.7 KDO19584.1 - 0.0029 17.4 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain VWA PF00092.28 KDO19584.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DnaJ_CXXCXGXG PF00684.19 KDO19584.1 - 0.15 12.4 3.5 4 7.9 0.1 2.7 2 0 0 2 2 2 0 DnaJ central domain Pkinase_Tyr PF07714.17 KDO19585.1 - 2.6e-26 92.5 0.0 3.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19585.1 - 3.4e-26 92.2 0.0 4.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO19585.1 - 0.00026 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 KDO19585.1 - 0.00046 20.7 0.0 0.00094 19.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Kinase-like PF14531.6 KDO19585.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ank_5 PF13857.6 KDO19585.1 - 0.0021 18.3 0.2 0.0066 16.7 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) APH PF01636.23 KDO19585.1 - 0.0025 17.8 0.1 0.0045 16.9 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ank PF00023.30 KDO19585.1 - 0.014 15.9 0.6 6.5 7.4 0.1 3.1 2 0 0 2 2 2 0 Ankyrin repeat Haspin_kinase PF12330.8 KDO19585.1 - 0.11 11.4 0.1 0.2 10.6 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO19585.1 - 0.12 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ank_3 PF13606.6 KDO19585.1 - 0.13 12.9 0.1 3.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KDO19586.1 - 9.5e-55 183.1 0.9 7.4e-17 61.7 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19586.1 - 3.3e-54 180.6 9.4 1.3e-11 44.7 0.0 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO19586.1 - 4.5e-44 147.0 3.7 5.7e-07 29.7 0.1 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KDO19586.1 - 1.3e-42 138.8 6.9 3.2e-06 27.0 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KDO19586.1 - 2.2e-41 139.4 8.7 1.8e-09 37.7 0.0 6.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) ANT PF03374.14 KDO19586.1 - 0.043 14.1 0.0 3.4 8.0 0.0 2.6 2 1 1 3 3 3 0 Phage antirepressor protein KilAC domain BLACT_WH PF17778.1 KDO19586.1 - 0.051 13.6 0.0 23 5.1 0.0 3.4 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain VHL_C PF17211.3 KDO19586.1 - 0.056 13.5 0.2 54 3.9 0.0 3.8 4 0 0 4 4 4 0 VHL box domain Pkinase_Tyr PF07714.17 KDO19587.1 - 2.5e-07 30.2 0.0 3.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19587.1 - 0.00016 21.2 0.0 0.00075 18.9 0.1 1.8 1 1 1 2 2 2 1 Protein kinase domain Peptidase_S28 PF05577.12 KDO19589.1 - 1.5e-107 360.1 0.1 1.8e-107 359.8 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 KDO19589.1 - 3.2e-05 23.7 0.2 7.9e-05 22.4 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 KDO19589.1 - 0.0003 19.6 0.1 0.00048 18.9 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Thiolase_N PF00108.23 KDO19590.1 - 9.5e-77 257.9 3.4 4.6e-76 255.6 1.3 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KDO19590.1 - 1e-49 167.2 1.2 2.8e-49 165.9 0.8 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Mito_carr PF00153.27 KDO19591.1 - 5.2e-59 196.2 0.1 4.4e-20 71.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KDO19591.1 - 0.00018 21.8 0.6 0.0015 18.9 0.2 2.3 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family CbtB PF09489.10 KDO19591.1 - 0.02 15.0 0.1 0.083 13.0 0.1 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF2570 PF10828.8 KDO19591.1 - 0.24 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1358 PF07096.11 KDO19592.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) eIF-5a PF01287.20 KDO19593.1 - 0.0021 18.1 0.2 0.0049 16.9 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SUI1 PF01253.22 KDO19594.1 - 7.8e-15 55.2 0.1 2.4e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KDO19594.1 - 2.8e-06 27.9 0.0 1e-05 26.1 0.0 2.1 1 0 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 KDO19594.1 - 0.0046 16.9 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 KDO19594.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain HECT PF00632.25 KDO19595.1 - 6.4e-60 203.2 0.0 9.1e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO19596.1 - 3.2e-08 32.7 18.4 0.0002 20.6 6.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Ank_4 PF13637.6 KDO19596.1 - 0.00011 22.7 1.1 0.013 16.1 0.2 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19596.1 - 0.00012 22.5 1.2 0.019 15.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19596.1 - 0.00029 21.1 0.2 2.1 9.2 0.1 3.9 2 0 0 2 2 2 2 Ankyrin repeat DZR PF12773.7 KDO19596.1 - 0.0016 18.4 8.1 0.0054 16.7 8.0 1.9 1 1 1 2 2 2 2 Double zinc ribbon Ank_5 PF13857.6 KDO19596.1 - 0.0057 16.9 1.1 0.062 13.6 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) PqqD PF05402.12 KDO19596.1 - 0.55 10.6 2.1 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) OrfB_Zn_ribbon PF07282.11 KDO19596.1 - 3.3 7.7 5.9 10 6.1 5.9 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.5 KDO19596.1 - 4.7 6.7 12.4 2.5 7.6 1.0 3.3 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Nop14 PF04147.12 KDO19596.1 - 6.2 4.9 20.9 0.069 11.4 6.6 2.4 2 0 0 2 2 2 0 Nop14-like family B-block_TFIIIC PF04182.12 KDO19597.1 - 1.2e-06 28.6 0.1 2.3e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC NDUF_B6 PF09782.9 KDO19597.1 - 0.043 14.0 0.2 0.089 12.9 0.2 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit PBP1_TM PF14812.6 KDO19597.1 - 3.5 8.1 6.0 42 4.6 2.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal fn3 PF00041.21 KDO19598.1 - 2.4e-45 152.8 0.0 3.6e-13 49.6 0.0 6.6 6 0 0 6 6 6 6 Fibronectin type III domain WD40 PF00400.32 KDO19598.1 - 3.2e-19 68.9 12.6 6.8e-06 26.7 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Pur_ac_phosph_N PF16656.5 KDO19598.1 - 1.1e-09 38.7 0.0 1.1 9.9 0.2 5.8 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain ANAPC4_WD40 PF12894.7 KDO19598.1 - 0.00045 20.5 0.1 0.61 10.4 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SusE PF14292.6 KDO19598.1 - 0.033 14.4 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 0 SusE outer membrane protein Na_H_Exchanger PF00999.21 KDO19599.1 - 4.4e-53 180.5 47.2 5.3e-53 180.2 47.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ank_2 PF12796.7 KDO19600.1 - 1.8e-21 76.5 8.5 3.5e-09 37.1 0.7 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO19600.1 - 1.4e-17 63.5 10.4 0.00017 21.8 0.1 5.3 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19600.1 - 7.1e-15 53.6 5.6 0.0014 19.0 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KDO19600.1 - 1.5e-14 54.2 7.3 0.0026 18.3 0.2 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO19600.1 - 5.6e-14 51.9 10.7 0.00017 21.9 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat PKS_DE PF18369.1 KDO19600.1 - 3 8.5 4.8 1.3 9.7 0.2 2.7 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain TFIID_20kDa PF03847.13 KDO19601.1 - 3.8e-19 69.0 0.1 7.5e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KDO19601.1 - 3e-05 24.1 0.1 3.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO19601.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SWIM PF04434.17 KDO19602.1 - 0.00023 20.8 0.2 0.00062 19.4 0.2 1.8 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 KDO19602.1 - 0.0061 16.9 0.0 0.099 13.1 0.0 2.9 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 KDO19602.1 - 1.4 8.9 4.1 0.61 10.1 1.0 2.0 2 0 0 2 2 2 0 MuDR family transposase Aa_trans PF01490.18 KDO19603.1 - 2.1e-59 201.3 24.4 2.6e-59 201.0 24.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.22 KDO19604.1 - 2.1e-21 75.5 0.2 7.6e-21 73.7 0.1 2.0 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 KDO19604.1 - 5.9e-16 58.9 4.0 5.9e-16 58.9 4.0 1.9 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_occluded PF16842.5 KDO19604.1 - 0.0033 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KDO19604.1 - 0.019 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO19604.1 - 0.023 14.8 0.0 0.069 13.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Pkinase_Tyr PF07714.17 KDO19605.1 - 8.4e-118 392.3 0.0 5.1e-41 140.7 0.0 4.0 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 KDO19605.1 - 3.8e-108 360.8 0.0 6.1e-39 134.0 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Kinase-like PF14531.6 KDO19605.1 - 3.6e-07 29.8 0.0 0.0025 17.2 0.0 3.3 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KDO19605.1 - 2.6e-06 27.0 0.9 0.31 10.4 0.1 3.9 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO19605.1 - 2e-05 23.6 0.3 0.032 13.0 0.1 2.4 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 KDO19605.1 - 0.0016 18.4 12.9 0.47 10.3 0.3 5.2 3 3 1 4 4 4 2 Phosphotransferase enzyme family Pkinase PF00069.25 KDO19609.1 - 3.1e-39 134.9 0.0 3.9e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19609.1 - 6.2e-39 133.8 0.0 7.9e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2207 PF09972.9 KDO19609.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase_fungal PF17667.1 KDO19609.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Beta-APP PF03494.13 KDO19609.1 - 0.046 13.6 1.4 0.089 12.7 1.4 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) BatD PF13584.6 KDO19609.1 - 0.048 12.5 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance S1FA PF04689.13 KDO19609.1 - 0.089 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA APH PF01636.23 KDO19609.1 - 0.094 12.6 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19609.1 - 0.18 10.7 0.0 3.1 6.6 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KDO19610.1 - 2.2e-11 43.6 0.0 1.1e-10 41.3 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19610.1 - 3e-07 30.1 0.0 1.1e-06 28.2 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KDO19610.1 - 1.3e-05 24.8 3.8 3e-05 23.7 0.1 2.7 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO19610.1 - 3.8e-05 24.0 10.2 0.0097 16.3 0.6 4.1 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Gram_pos_anchor PF00746.21 KDO19610.1 - 0.068 13.1 0.9 0.13 12.2 0.9 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LRR_1 PF00560.33 KDO19610.1 - 0.076 13.6 7.9 2.4 9.0 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat CD34_antigen PF06365.12 KDO19610.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Ribosomal_L12 PF00542.19 KDO19611.1 - 3.1e-23 81.9 8.2 6.6e-23 80.8 8.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KDO19611.1 - 8e-05 22.3 2.6 8e-05 22.3 2.6 3.2 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain Pkinase_Tyr PF07714.17 KDO19613.1 - 6e-28 97.8 0.0 9.8e-28 97.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19613.1 - 8e-27 94.2 0.0 9.7e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO19613.1 - 0.00062 19.2 0.1 0.00087 18.7 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO19613.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KDO19614.1 - 5.3e-29 101.4 0.0 6.9e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19614.1 - 1.9e-24 86.4 0.0 3.4e-24 85.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO19614.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CCDC53 PF10152.9 KDO19615.1 - 8.9e-06 26.2 0.1 8.9e-06 26.2 0.1 2.6 3 1 0 3 3 3 1 Subunit CCDC53 of WASH complex BAR PF03114.18 KDO19615.1 - 7.9e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 BAR domain Thioredoxin PF00085.20 KDO19618.1 - 1.2e-18 67.0 0.0 1.4e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO19618.1 - 8.4e-05 23.0 0.2 0.0017 18.8 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KDO19618.1 - 0.048 14.0 0.0 0.14 12.5 0.0 1.6 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KDO19618.1 - 0.049 13.4 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Sec7 PF01369.20 KDO19619.1 - 9.5e-61 204.7 0.2 2e-60 203.6 0.1 1.6 2 0 0 2 2 2 1 Sec7 domain HEAT PF02985.22 KDO19619.1 - 0.15 12.4 0.2 0.72 10.3 0.2 2.3 1 0 0 1 1 1 0 HEAT repeat V_ATPase_I PF01496.19 KDO19620.1 - 4 5.2 4.6 5.9 4.7 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 KDO19621.1 - 8.5e-38 130.2 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19621.1 - 7.5e-14 51.6 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO19621.1 - 0.00015 21.1 0.1 0.00026 20.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO19621.1 - 0.00017 21.6 1.4 0.0045 17.0 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO19621.1 - 0.00087 18.9 0.1 0.0089 15.6 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KDO19621.1 - 0.0025 16.6 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 KDO19621.1 - 0.054 14.0 0.2 0.14 12.7 0.2 1.8 1 1 0 1 1 1 0 PH domain Choline_kinase PF01633.20 KDO19621.1 - 0.18 11.4 0.3 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase MBOAT PF03062.19 KDO19623.1 - 9.3e-36 123.9 8.7 1.7e-35 123.1 8.2 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CBP_BcsF PF11120.8 KDO19623.1 - 0.61 10.3 2.6 28 4.9 0.1 3.0 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF DNA_pol_A_exoN PF18305.1 KDO19624.1 - 0.047 14.0 2.1 0.075 13.3 0.2 2.3 2 1 0 2 2 2 0 3' to 5' exonuclease C-terminal domain MerB PF03243.15 KDO19624.1 - 0.091 12.9 0.7 0.27 11.4 0.6 1.9 2 0 0 2 2 2 0 Alkylmercury lyase Glyco_hydro_42M PF08532.10 KDO19624.1 - 0.1 12.1 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain DUF463 PF04317.12 KDO19625.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 YcjX-like family, DUF463 Pkinase_Tyr PF07714.17 KDO19626.1 - 2.7e-56 190.7 0.0 1.3e-41 142.6 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KDO19626.1 - 1.3e-49 168.9 0.0 2e-40 138.8 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Kdo PF06293.14 KDO19626.1 - 2.3e-08 33.7 0.7 0.00085 18.7 0.3 2.4 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO19626.1 - 5.7e-06 25.8 0.5 0.076 12.3 0.1 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO19626.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO19626.1 - 0.073 13.0 2.8 0.12 12.3 0.8 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family IATP PF04568.12 KDO19627.1 - 0.0086 16.5 2.2 0.019 15.4 2.2 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP T4SS PF07996.11 KDO19627.1 - 0.019 15.4 4.2 0.021 15.2 2.6 1.7 1 1 0 1 1 1 0 Type IV secretion system proteins bZIP_2 PF07716.15 KDO19627.1 - 0.046 13.8 7.1 0.12 12.5 7.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF3573 PF12097.8 KDO19627.1 - 0.086 11.7 1.1 0.13 11.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlxA PF14282.6 KDO19627.1 - 0.18 11.8 9.9 0.027 14.4 5.6 1.9 2 0 0 2 2 2 0 FlxA-like protein PRP9_N PF16958.5 KDO19627.1 - 1.7 8.7 8.9 0.46 10.5 5.1 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus bZIP_1 PF00170.21 KDO19627.1 - 2 8.6 8.5 2.6 8.2 6.8 2.0 3 0 0 3 3 3 0 bZIP transcription factor Bud13 PF09736.9 KDO19627.1 - 6.6 7.1 10.0 6.9 7.1 8.3 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Jnk-SapK_ap_N PF09744.9 KDO19627.1 - 6.9 6.9 9.7 31 4.7 9.4 2.2 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 FlxA PF14282.6 KDO19628.1 - 0.13 12.3 4.7 1.4 8.9 1.6 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF2205 PF10224.9 KDO19628.1 - 1 9.4 11.9 2.9 7.9 2.0 3.1 2 1 1 3 3 3 0 Short coiled-coil protein DivIC PF04977.15 KDO19628.1 - 1.7 8.5 9.1 2.7 7.8 2.6 2.5 2 0 0 2 2 2 0 Septum formation initiator PRKG1_interact PF15898.5 KDO19628.1 - 1.9 9.4 16.8 3.6 8.5 6.5 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PhnG PF06754.12 KDO19628.1 - 2.1 8.3 12.0 1.5 8.8 1.1 2.8 2 1 1 3 3 3 0 Phosphonate metabolism protein PhnG FAD_syn PF06574.12 KDO19630.1 - 0.05 13.5 0.1 0.063 13.2 0.1 1.1 1 0 0 1 1 1 0 FAD synthetase IPK PF03770.16 KDO19632.1 - 3.9e-51 173.7 0.0 1.1e-50 172.2 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase Glyoxalase PF00903.25 KDO19633.1 - 4.5e-06 26.9 0.0 8.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO19633.1 - 5.3e-05 24.0 0.0 6.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KDO19633.1 - 0.0003 20.7 0.0 0.00045 20.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Autoind_bind PF03472.15 KDO19633.1 - 0.048 13.1 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Autoinducer binding domain TruB_C PF09142.11 KDO19633.1 - 0.075 12.8 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PX PF00787.24 KDO19634.1 - 6.7e-05 22.8 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Aminotran_MocR PF12897.7 KDO19634.1 - 0.051 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase TPR_2 PF07719.17 KDO19635.1 - 3.9e-14 51.5 12.1 0.0035 17.3 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO19635.1 - 1.2e-09 38.6 19.6 6.1e-05 23.6 0.4 6.7 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO19635.1 - 1.6e-08 34.7 28.7 0.00048 20.7 0.1 9.9 7 3 4 11 11 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19635.1 - 2.2e-07 30.4 10.6 0.0032 17.2 0.0 6.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO19635.1 - 2e-06 27.6 4.3 0.018 15.2 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO19635.1 - 8.6e-06 25.3 6.6 0.043 13.5 0.1 5.7 5 1 1 6 6 6 2 TPR repeat TPR_12 PF13424.6 KDO19635.1 - 6e-05 23.3 33.1 0.085 13.2 0.6 7.2 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO19635.1 - 7.2e-05 22.6 10.6 0.51 10.5 0.1 6.7 7 1 1 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO19635.1 - 0.00019 21.6 7.5 0.063 13.5 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KDO19635.1 - 0.00083 19.5 13.2 0.33 11.1 0.1 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO19635.1 - 0.0025 18.3 24.5 0.15 12.6 0.1 6.7 3 3 1 6 6 6 3 Tetratricopeptide repeat Coatomer_E PF04733.14 KDO19635.1 - 0.0037 16.7 1.9 5.2 6.4 0.0 3.9 3 1 1 4 4 4 1 Coatomer epsilon subunit TPR_21 PF09976.9 KDO19635.1 - 0.039 13.7 6.7 1.5 8.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KDO19635.1 - 0.43 10.5 0.0 0.43 10.5 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO19635.1 - 0.52 10.8 0.0 0.52 10.8 0.0 6.6 9 1 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO19635.1 - 3.4 8.5 13.7 29 5.6 0.1 6.7 7 2 1 8 8 7 0 Tetratricopeptide repeat LOR PF04525.12 KDO19638.1 - 1.5e-10 41.0 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related LOR PF04525.12 KDO19639.1 - 2.8e-08 33.6 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related zf-CCCH PF00642.24 KDO19641.1 - 1.4e-20 72.7 16.2 4.2e-12 45.7 5.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO19641.1 - 3.4e-13 49.2 16.8 1.9e-07 30.9 5.4 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KDO19641.1 - 1.1e-12 47.4 12.8 4e-07 29.7 2.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KDO19641.1 - 7.9e-05 23.3 9.3 0.011 16.4 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KDO19641.1 - 0.00023 21.5 10.3 0.0042 17.5 1.5 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger PMR5N PF14416.6 KDO19641.1 - 0.61 10.4 2.9 6.7 7.1 0.3 2.5 1 1 1 2 2 2 0 PMR5 N terminal Domain Transp_Tc5_C PF04236.15 KDO19642.1 - 0.67 10.4 5.8 1.5 9.2 0.8 2.7 1 1 2 3 3 3 0 Tc5 transposase C-terminal domain HAP1_N PF04849.13 KDO19644.1 - 0.23 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF4431 PF14485.6 KDO19645.1 - 0.037 13.8 0.2 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) ATG16 PF08614.11 KDO19646.1 - 0.0029 17.9 11.1 0.0053 17.0 11.1 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) FAM184 PF15665.5 KDO19646.1 - 0.011 15.5 7.8 0.017 14.9 7.8 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 KDO19646.1 - 0.024 14.6 9.2 0.034 14.2 5.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KDO19646.1 - 0.031 14.7 4.0 0.04 14.4 4.0 1.2 1 0 0 1 1 1 0 Fez1 FAM76 PF16046.5 KDO19646.1 - 0.076 12.4 4.4 0.092 12.1 4.4 1.1 1 0 0 1 1 1 0 FAM76 protein HALZ PF02183.18 KDO19646.1 - 0.15 12.3 1.3 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phage_GP20 PF06810.11 KDO19646.1 - 0.42 10.4 6.9 0.56 10.0 5.7 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Activator-TraM PF11657.8 KDO19646.1 - 0.51 10.2 6.9 0.73 9.7 6.2 1.6 1 1 0 1 1 1 0 Transcriptional activator TraM DUF1664 PF07889.12 KDO19646.1 - 1.3 9.0 4.8 2 8.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AEP1 PF17049.5 KDO19648.1 - 0.0085 15.2 0.3 0.028 13.5 0.3 1.7 1 1 0 1 1 1 1 ATPase expression protein 1 DUF4071 PF13281.6 KDO19648.1 - 0.022 13.8 1.2 0.035 13.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF5309 PF17236.2 KDO19648.1 - 0.043 13.2 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5309) OTU PF02338.19 KDO19649.1 - 4.1e-11 43.5 0.1 1.1e-10 42.1 0.1 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Wbp11 PF09429.10 KDO19649.1 - 0.012 16.0 0.6 0.012 16.0 0.6 2.6 2 1 0 2 2 2 0 WW domain binding protein 11 SnoaL_2 PF12680.7 KDO19652.1 - 0.13 12.9 1.0 0.8 10.4 0.4 2.4 1 1 1 2 2 2 0 SnoaL-like domain bZIP_2 PF07716.15 KDO19653.1 - 0.028 14.5 7.3 0.05 13.7 7.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Defensin_5 PF18251.1 KDO19653.1 - 0.094 12.8 0.9 0.27 11.4 0.2 2.0 2 0 0 2 2 2 0 Fungal defensin Copsin bZIP_1 PF00170.21 KDO19653.1 - 0.26 11.4 4.4 0.52 10.5 4.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KDO19656.1 - 0.014 15.4 7.3 0.027 14.6 7.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Trm112p PF03966.16 KDO19657.1 - 0.0027 18.2 0.4 0.0068 17.0 0.4 1.6 1 1 0 1 1 1 1 Trm112p-like protein ELYS PF13934.6 KDO19658.1 - 3.2e-09 37.1 4.5 3.2e-09 37.1 4.5 1.7 2 0 0 2 2 2 1 Nuclear pore complex assembly SWIM PF04434.17 KDO19660.1 - 0.0021 17.7 0.1 0.0043 16.7 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger HA PF03457.14 KDO19662.1 - 1.4e-18 66.9 0.0 7.7e-07 29.3 0.0 4.7 5 0 0 5 5 5 4 Helicase associated domain PHTB1_C PF14728.6 KDO19663.1 - 1.3e-60 205.5 0.3 1.7e-60 205.1 0.3 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 KDO19663.1 - 3.5e-59 201.2 0.0 5e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus Med14 PF08638.11 KDO19663.1 - 0.0046 16.4 0.3 0.0079 15.6 0.3 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 PWWP PF00855.17 KDO19665.1 - 8e-15 55.0 0.2 8e-15 55.0 0.2 2.3 2 1 0 2 2 2 1 PWWP domain PE-PPE PF08237.11 KDO19665.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain PHTB1_C PF14728.6 KDO19666.1 - 2.4e-111 372.5 2.5 7.4e-111 370.9 2.5 1.7 1 1 0 1 1 1 1 PTHB1 C-terminus Med14 PF08638.11 KDO19666.1 - 0.0048 16.3 0.1 0.0083 15.6 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 LtuB PF17455.2 KDO19666.1 - 0.15 12.7 0.5 8.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Late transcription unit B NPCBM_assoc PF10633.9 KDO19666.1 - 1.8 8.8 5.4 2.7 8.3 3.7 2.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Peptidase_S74 PF13884.6 KDO19668.1 - 3.2e-08 33.8 0.4 5.1e-08 33.1 0.4 1.3 1 0 0 1 1 1 1 Chaperone of endosialidase PSI PF01437.25 KDO19668.1 - 1.6 9.3 23.4 0.013 16.1 11.7 2.3 2 0 0 2 2 2 0 Plexin repeat Tafi-CsgC PF10610.9 KDO19669.1 - 0.099 12.8 2.1 4.4 7.6 0.1 2.3 1 1 1 2 2 2 0 Thin aggregative fimbriae synthesis protein Epiglycanin_TR PF05647.11 KDO19669.1 - 0.34 10.8 7.1 3.4 7.7 0.6 2.5 1 1 1 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Peptidase_S74 PF13884.6 KDO19670.1 - 1.3e-09 38.3 0.1 2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Chaperone of endosialidase ABC_tran PF00005.27 KDO19672.1 - 4e-21 76.0 0.5 1.8e-10 41.5 0.0 2.3 1 1 1 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO19672.1 - 2.4e-05 23.9 1.6 0.045 13.2 0.3 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 KDO19672.1 - 2.9e-05 23.9 0.4 5.6e-05 22.9 0.4 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 KDO19672.1 - 0.0053 17.1 0.1 0.0081 16.5 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KDO19672.1 - 0.007 16.4 0.2 0.018 15.1 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 KDO19672.1 - 0.008 16.3 0.4 0.025 14.7 0.4 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 KDO19672.1 - 0.015 15.1 0.3 3.8 7.2 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO19672.1 - 0.025 14.3 0.4 0.09 12.5 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KDO19672.1 - 0.058 12.3 0.2 0.12 11.3 0.2 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KDO19672.1 - 0.061 13.6 0.7 0.47 10.7 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KDO19672.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 KDO19672.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 KDO19673.1 - 4.6e-15 56.0 0.0 6.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO19673.1 - 2e-09 37.1 0.0 5.7e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO19673.1 - 1.2e-06 29.3 2.1 4.7e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family TTL PF03133.15 KDO19674.1 - 5.2e-73 245.7 0.0 1.1e-72 244.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO19674.1 - 7.2e-07 28.7 2.7 7.7e-06 25.3 0.0 3.2 3 1 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO19674.1 - 0.076 12.2 0.0 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KDO19674.1 - 0.19 11.8 0.0 0.83 9.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain ABC_tran PF00005.27 KDO19675.1 - 3.3e-50 170.2 0.0 1.2e-30 106.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO19675.1 - 4.6e-47 161.0 28.6 9.9e-35 120.5 15.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO19675.1 - 2.3e-10 40.3 4.5 0.011 15.1 0.4 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO19675.1 - 2.5e-07 30.8 0.2 0.015 15.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KDO19675.1 - 1.4e-06 28.5 0.4 0.00015 21.9 0.0 2.6 3 0 0 3 3 2 1 Dynamin family AAA_22 PF13401.6 KDO19675.1 - 5.9e-06 26.6 0.0 0.091 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO19675.1 - 1.4e-05 24.7 2.1 0.068 12.9 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO19675.1 - 5.3e-05 22.9 0.2 0.01 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO19675.1 - 7.5e-05 22.0 0.1 0.15 11.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 KDO19675.1 - 9.1e-05 22.9 0.4 0.066 13.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KDO19675.1 - 0.0001 22.3 3.9 0.35 10.6 0.2 3.7 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO19675.1 - 0.00011 22.2 0.3 0.053 13.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KDO19675.1 - 0.0012 18.9 2.7 0.12 12.5 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KDO19675.1 - 0.0018 18.8 0.6 1.3 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 KDO19675.1 - 0.002 17.1 0.6 1.5 7.6 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KDO19675.1 - 0.0029 16.7 0.1 2.5 7.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KDO19675.1 - 0.0067 15.8 1.6 1.6 8.0 0.2 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family cobW PF02492.19 KDO19675.1 - 0.012 15.3 0.7 0.76 9.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KDO19675.1 - 0.016 15.0 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KDO19675.1 - 0.019 14.7 1.7 6 6.5 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 KDO19675.1 - 0.048 14.2 0.1 8.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO19675.1 - 0.051 13.1 0.3 8.1 5.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KDO19675.1 - 0.059 13.5 0.1 3.4 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KDO19675.1 - 0.065 13.6 0.0 9.9 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KDO19675.1 - 0.09 13.0 0.1 26 5.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KDO19675.1 - 0.15 11.9 2.2 3.6 7.3 0.3 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 KDO19675.1 - 0.22 10.3 0.2 2 7.2 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF2075 PF09848.9 KDO19675.1 - 0.25 10.6 0.3 5.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KDO19675.1 - 0.32 10.3 0.8 5.3 6.3 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin CHAT PF12770.7 KDO19677.1 - 4.7e-13 49.2 0.0 8.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 CHAT domain IstB_IS21 PF01695.17 KDO19677.1 - 0.0028 17.4 0.1 0.0073 16.0 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KDO19677.1 - 0.0071 16.7 0.0 0.043 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KDO19677.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO19677.1 - 0.082 13.2 0.4 0.97 9.7 0.4 2.5 1 1 0 1 1 1 0 AAA domain SQHop_cyclase_N PF13249.6 KDO19677.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain SET PF00856.28 KDO19679.1 - 1.4e-23 84.1 0.9 2.1e-09 38.0 0.1 3.8 2 2 1 3 3 3 2 SET domain SAF PF08666.12 KDO19679.1 - 0.00097 19.7 0.0 2.8 8.6 0.0 3.5 4 0 0 4 4 4 2 SAF domain DUF378 PF04070.12 KDO19680.1 - 0.034 14.0 0.3 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF378) DLH PF01738.18 KDO19681.1 - 3.3e-25 88.9 0.0 4e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KDO19681.1 - 1.1e-07 31.7 1.9 6.6e-07 29.2 1.5 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KDO19681.1 - 0.037 13.6 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KDO19681.1 - 0.064 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HSF_DNA-bind PF00447.17 KDO19682.1 - 9.2e-15 55.0 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Integrin_b_cyt PF08725.11 KDO19682.1 - 0.0011 18.5 21.2 0.013 15.2 0.1 6.9 3 1 5 8 8 8 3 Integrin beta cytoplasmic domain MIF4G_like PF09088.11 KDO19682.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 MIF4G like HSF_DNA-bind PF00447.17 KDO19683.1 - 6.5e-08 33.1 0.0 9.8e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 HSF-type DNA-binding Dmrt1 PF12374.8 KDO19683.1 - 6.5 7.3 7.8 24 5.4 1.3 2.6 2 1 1 3 3 3 0 Double-sex mab3 related transcription factor 1 Pkinase PF00069.25 KDO19684.1 - 1.3e-51 175.5 0.0 1.7e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19684.1 - 5.4e-30 104.5 0.0 1.6e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19684.1 - 8.5e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO19684.1 - 0.00013 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO19684.1 - 0.00079 19.4 0.0 0.21 11.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO19684.1 - 0.027 13.8 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.24 KDO19686.1 - 4.4e-09 36.3 0.0 7.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO19689.1 - 1.7e-10 40.9 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 KDO19690.1 - 1.2e-47 162.4 0.0 1.5e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19690.1 - 4.3e-45 154.1 0.0 5.7e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO19690.1 - 0.016 14.0 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase GcpE PF04551.14 KDO19690.1 - 0.017 14.2 0.0 0.066 12.3 0.0 1.7 2 0 0 2 2 2 0 GcpE protein APH PF01636.23 KDO19690.1 - 0.065 13.2 0.2 0.13 12.1 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19690.1 - 0.12 11.3 0.0 0.5 9.2 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain SVIP PF15811.5 KDO19691.1 - 1.3e-05 25.5 1.3 2.2e-05 24.8 1.3 1.4 1 0 0 1 1 1 1 Small VCP/p97-interacting protein Not3 PF04065.15 KDO19694.1 - 1.6e-85 286.2 14.9 2.1e-85 285.9 14.9 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KDO19694.1 - 4.4e-42 143.3 6.6 1.2e-41 141.9 6.6 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family FYVE PF01363.21 KDO19695.1 - 0.00054 20.0 24.4 0.0016 18.6 24.4 1.8 1 1 0 1 1 1 1 FYVE zinc finger Tim44 PF04280.15 KDO19697.1 - 6.4e-06 26.3 1.5 6.2e-05 23.1 1.5 2.2 1 1 0 1 1 1 1 Tim44-like domain Es2 PF09751.9 KDO19698.1 - 2.9e-55 188.8 13.0 2.9e-44 152.5 5.8 2.3 1 1 1 2 2 2 2 Nuclear protein Es2 p450 PF00067.22 KDO19699.1 - 1.2e-34 119.9 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_1 PF11427.8 KDO19699.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_38 PF13936.6 KDO19699.1 - 0.00061 19.5 1.4 0.0023 17.6 1.4 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain TMEM208_SND2 PF05620.11 KDO19702.1 - 1e-06 28.6 0.9 1.2e-06 28.5 0.9 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 zf-U1 PF06220.12 KDO19704.1 - 8.9e-06 25.4 1.1 1.4e-05 24.7 1.1 1.4 1 0 0 1 1 1 1 U1 zinc finger Spt5_N PF11942.8 KDO19704.1 - 0.012 16.6 4.6 0.016 16.1 4.6 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal bZIP_1 PF00170.21 KDO19705.1 - 1.7 8.8 5.9 0.75 9.9 3.1 1.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_1 PF00170.21 KDO19707.1 - 0.54 10.4 3.7 1.3 9.2 3.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_1 PF00170.21 KDO19708.1 - 0.1 12.7 4.8 0.23 11.6 4.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor RGS PF00615.19 KDO19709.1 - 0.00011 22.5 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4728 PF15860.5 KDO19710.1 - 2.2 9.0 6.2 0.48 11.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) DM4_12 PF07841.13 KDO19711.1 - 0.11 13.2 0.1 0.33 11.7 0.0 1.7 1 1 1 2 2 2 0 DM4/DM12 family DUF4139 PF13598.6 KDO19713.1 - 0.0099 15.6 0.2 0.019 14.7 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DSPc PF00782.20 KDO19714.1 - 2.5e-10 40.3 0.0 3.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KDO19714.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Tax PF02959.16 KDO19715.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax CEBP_ZZ PF16366.5 KDO19716.1 - 0.00051 20.2 2.7 0.0016 18.6 2.7 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain TPR_2 PF07719.17 KDO19717.1 - 3.8e-09 36.0 3.0 0.00068 19.6 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19717.1 - 4.7e-07 29.4 1.3 0.025 14.4 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO19717.1 - 6.1e-05 23.6 7.1 0.00022 21.8 6.8 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO19717.1 - 0.0021 18.7 5.1 0.033 15.0 0.7 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO19717.1 - 0.0027 17.9 3.8 0.0058 16.9 2.6 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO19717.1 - 0.0099 15.5 2.1 1.5 8.5 0.3 2.5 2 0 0 2 2 2 2 TPR repeat 2OG-FeII_Oxy_3 PF13640.6 KDO19717.1 - 0.021 15.7 0.0 0.04 14.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_19 PF14559.6 KDO19717.1 - 0.028 14.9 3.4 0.09 13.3 3.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO19717.1 - 0.05 13.8 0.8 0.12 12.7 0.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KDO19717.1 - 1.2 8.7 3.3 1.2 8.7 0.5 2.2 2 0 0 2 2 2 0 SHNi-TPR Methyltransf_2 PF00891.18 KDO19718.1 - 6.1e-45 153.1 0.1 7.5e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KDO19718.1 - 3.5e-09 36.5 0.0 7.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 KDO19718.1 - 0.00034 20.4 0.0 0.00096 18.9 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 KDO19718.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DprA_WH PF17782.1 KDO19718.1 - 0.031 14.4 0.4 0.07 13.3 0.4 1.5 1 0 0 1 1 1 0 DprA winged helix domain MarR_2 PF12802.7 KDO19718.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 MarR family AAA_assoc_C PF09821.9 KDO19718.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal AAA-associated domain Pkinase PF00069.25 KDO19719.1 - 1.1e-46 159.3 0.0 1.1e-45 156.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19719.1 - 6.9e-43 146.8 0.0 1.6e-41 142.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO19719.1 - 0.0077 16.2 0.7 0.046 13.6 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19719.1 - 0.02 13.8 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain CTP_transf_1 PF01148.20 KDO19720.1 - 2.3e-69 234.1 22.1 3e-69 233.7 22.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Lenti_VIF_2 PF07401.12 KDO19720.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein ELL PF10390.9 KDO19721.1 - 0.0034 16.9 1.7 0.0037 16.8 1.7 1.2 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL AsnA PF03590.15 KDO19721.1 - 0.013 15.3 1.9 0.016 14.9 1.9 1.1 1 0 0 1 1 1 0 Aspartate-ammonia ligase HEPN_DZIP3 PF18738.1 KDO19721.1 - 0.041 13.6 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Med28 PF11594.8 KDO19721.1 - 0.042 13.9 1.3 0.65 10.1 0.0 2.3 1 1 1 2 2 2 0 Mediator complex subunit 28 PMEI PF04043.15 KDO19721.1 - 0.054 13.8 5.0 0.21 11.9 4.9 1.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Prominin PF05478.11 KDO19721.1 - 0.092 10.7 1.5 0.12 10.4 1.5 1.2 1 0 0 1 1 1 0 Prominin Lectin_N PF03954.14 KDO19721.1 - 0.14 11.9 1.7 0.76 9.5 0.6 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain V-SNARE PF05008.15 KDO19721.1 - 0.16 12.4 4.3 0.24 11.8 2.0 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Mt_ATP-synt_D PF05873.12 KDO19721.1 - 0.17 11.7 4.4 0.38 10.6 3.2 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) ParE_toxin PF05016.15 KDO19721.1 - 0.19 12.4 1.0 0.76 10.4 0.5 2.1 1 1 1 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE FAM184 PF15665.5 KDO19721.1 - 0.26 11.1 10.4 0.46 10.2 10.4 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Sipho_Gp157 PF05565.11 KDO19721.1 - 0.85 9.6 8.5 4.4 7.3 4.1 2.8 1 1 2 3 3 3 0 Siphovirus Gp157 KxDL PF10241.9 KDO19721.1 - 1.1 9.5 6.0 2.5 8.4 1.0 3.0 2 1 0 3 3 3 0 Uncharacterized conserved protein MFS_1 PF07690.16 KDO19722.1 - 1.3e-34 119.7 36.5 1.3e-34 119.7 36.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sex_peptide PF08138.11 KDO19722.1 - 0.068 13.3 0.4 0.21 11.8 0.4 1.8 1 0 0 1 1 1 0 Sex peptide (SP) family DNA_pol_E_B PF04042.16 KDO19723.1 - 8.4e-39 133.1 0.7 1.2e-38 132.6 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KDO19723.1 - 7e-05 22.9 0.9 0.0003 20.9 0.9 1.9 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.25 KDO19725.1 - 1.3e-33 116.5 0.0 1.5e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19725.1 - 7.2e-30 104.1 0.0 8.5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KDO19726.1 - 6.7e-56 189.4 0.0 1.1e-55 188.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19726.1 - 1.9e-49 168.4 0.0 3.3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO19726.1 - 0.0016 18.5 0.7 0.012 15.6 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO19726.1 - 0.008 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO19727.1 - 1.3e-30 106.6 0.0 1.9e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19727.1 - 1.6e-23 83.4 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Use1 PF09753.9 KDO19728.1 - 1.3e-07 31.7 0.7 1.6e-07 31.3 0.5 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 CinA_KH PF18146.1 KDO19728.1 - 0.016 15.3 0.5 0.039 14.1 0.5 1.8 1 1 1 2 2 2 0 Damage-inducible protein CinA KH domain Imm7 PF15585.6 KDO19728.1 - 0.024 14.9 0.4 0.062 13.6 0.2 1.6 1 1 1 2 2 2 0 Immunity protein 7 RdgC PF04381.12 KDO19728.1 - 0.034 13.4 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Putative exonuclease, RdgC DUF2937 PF11157.8 KDO19728.1 - 0.06 13.1 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) UTP25 PF06862.12 KDO19730.1 - 8.5e-42 143.5 0.3 9.1e-42 143.4 0.3 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ank_2 PF12796.7 KDO19732.1 - 3.7e-50 168.4 13.5 9.2e-15 55.0 0.2 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19732.1 - 6.3e-39 131.9 16.9 1e-09 38.7 0.3 7.1 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19732.1 - 8.5e-37 124.8 21.8 1.1e-07 32.0 0.1 7.9 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19732.1 - 1e-36 120.7 9.8 0.0003 21.0 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KDO19732.1 - 1.5e-29 101.1 21.1 0.0001 22.6 0.6 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ion_trans PF00520.31 KDO19732.1 - 0.0031 16.8 16.2 0.0031 16.8 16.2 2.2 2 0 0 2 2 2 1 Ion transport protein MCM PF00493.23 KDO19733.1 - 2.5e-98 327.7 0.0 3.7e-98 327.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KDO19733.1 - 3.4e-37 127.1 0.0 6.5e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KDO19733.1 - 8.1e-23 80.7 4.3 1.5e-22 79.8 1.0 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KDO19733.1 - 2.2e-18 66.8 0.7 7.3e-18 65.1 0.3 2.1 2 0 0 2 2 1 1 MCM N-terminal domain MCM2_N PF12619.8 KDO19733.1 - 2.9e-10 40.6 33.1 2.9e-10 40.6 33.1 3.8 3 1 1 4 4 4 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KDO19733.1 - 8e-10 38.5 0.1 2.7e-07 30.2 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO19733.1 - 2.4e-05 24.4 0.0 9.1e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KDO19733.1 - 0.00011 22.0 0.1 0.0019 18.0 0.0 2.9 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KDO19733.1 - 0.011 15.5 0.0 0.12 12.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KDO19733.1 - 0.02 15.3 0.0 0.079 13.4 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 KDO19733.1 - 0.027 14.6 1.0 0.064 13.4 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Rz1 PF06085.11 KDO19733.1 - 0.12 12.1 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor KBP_C PF12309.8 KDO19735.1 - 1.7e-51 175.8 0.0 6.2e-47 160.8 0.0 2.2 2 0 0 2 2 2 2 KIF-1 binding protein C terminal TPR_7 PF13176.6 KDO19735.1 - 0.0023 17.8 11.6 2.9 8.1 0.4 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19735.1 - 0.0047 16.7 0.1 0.86 9.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO19735.1 - 0.016 15.0 6.7 30 4.7 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO19735.1 - 0.018 15.3 10.4 2.7 8.4 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO19735.1 - 0.02 15.0 13.7 0.4 10.9 0.0 6.0 7 1 0 7 7 7 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 KDO19736.1 - 3.9e-13 49.5 5.3 7.7e-13 48.6 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO19736.1 - 3.2e-11 42.9 5.4 6.1e-11 42.0 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO19736.1 - 2.4e-09 37.3 7.3 5.2e-09 36.2 7.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO19736.1 - 4.2e-08 32.9 4.1 7.8e-08 32.1 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO19736.1 - 9.3e-07 28.5 5.4 1.4e-06 28.0 4.4 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KDO19736.1 - 9.3e-06 25.4 5.8 1.6e-05 24.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO19736.1 - 1.2e-05 25.2 3.9 2.7e-05 24.1 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO19736.1 - 5e-05 23.2 3.1 8.3e-05 22.5 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO19736.1 - 6.6e-05 22.7 2.9 0.00012 21.9 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO19736.1 - 0.00053 20.0 3.6 0.0009 19.3 3.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KDO19736.1 - 0.0058 16.8 1.7 0.019 15.1 1.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING RINGv PF12906.7 KDO19736.1 - 0.011 15.8 2.6 0.025 14.7 2.6 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KDO19736.1 - 0.024 14.4 4.0 0.048 13.5 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KDO19736.1 - 0.026 14.6 3.4 0.062 13.4 3.4 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_10 PF16685.5 KDO19736.1 - 0.041 14.0 1.2 0.073 13.2 1.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KDO19736.1 - 0.25 11.6 6.2 1.1 9.4 6.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KDO19736.1 - 0.29 10.8 6.0 0.58 9.8 6.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KDO19736.1 - 3.5 8.0 7.2 6.7 7.1 7.2 1.5 1 1 0 1 1 1 0 RING-like domain Utp14 PF04615.13 KDO19737.1 - 6.6e-99 332.5 43.7 6.6e-99 332.5 43.7 2.1 2 0 0 2 2 2 1 Utp14 protein Phage_rep_O PF04492.13 KDO19737.1 - 0.082 13.5 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage replication protein O Utp14 PF04615.13 KDO19738.1 - 1.2e-54 186.1 20.5 1.2e-54 186.1 20.5 1.5 1 1 0 1 1 1 1 Utp14 protein GAS PF13851.6 KDO19739.1 - 0.18 11.2 15.3 3.9 6.8 2.2 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.6 KDO19739.1 - 1.5 9.0 6.9 4.2 7.5 2.9 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 KDO19739.1 - 1.9 9.1 6.9 0.76 10.4 1.1 2.9 2 1 0 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 KDO19739.1 - 2.3 9.2 18.2 0.082 13.8 4.3 3.3 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 KDO19739.1 - 7.8 6.6 30.3 4.6 7.3 5.8 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein SDF PF00375.18 KDO19740.1 - 4.2e-44 151.2 34.0 1.2e-24 87.0 13.4 3.9 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family Peptidase_C1 PF00112.23 KDO19741.1 - 4.6e-58 196.9 9.3 6.9e-58 196.3 9.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO19741.1 - 0.015 14.1 1.6 0.23 10.2 0.1 2.3 2 0 0 2 2 2 0 Peptidase C1-like family SDF PF00375.18 KDO19743.1 - 1.6e-39 136.0 17.3 1.3e-22 80.4 11.3 2.4 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family DUF4658 PF15555.6 KDO19743.1 - 1.8 8.7 4.3 16 5.7 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) AMP-binding PF00501.28 KDO19744.1 - 9.3e-60 202.4 0.0 1.3e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO19744.1 - 3.6e-16 59.9 0.1 1.3e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF5476 PF17570.2 KDO19745.1 - 0.053 13.9 5.2 0.92 9.9 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5476) MT PF12777.7 KDO19746.1 - 1.3e-14 54.0 0.0 3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor IQ PF00612.27 KDO19746.1 - 0.019 14.7 19.1 0.41 10.6 0.6 4.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif LRR_6 PF13516.6 KDO19747.1 - 1.4e-06 27.9 4.2 2.2 8.5 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich repeat MIP PF00230.20 KDO19748.1 - 1.9e-34 119.3 2.4 2.6e-34 118.9 2.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein PHTB1_C PF14728.6 KDO19748.1 - 0.013 14.6 3.4 0.12 11.5 0.3 2.1 1 1 1 2 2 2 0 PTHB1 C-terminus MIP PF00230.20 KDO19749.1 - 9.9e-56 189.0 8.7 1.3e-55 188.6 8.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1418 PF07214.12 KDO19749.1 - 0.55 10.1 2.5 0.33 10.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF2154 PF09922.9 KDO19750.1 - 1e-05 25.4 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF Mor PF08765.11 KDO19750.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family Peptidase_C1 PF00112.23 KDO19751.1 - 2.4e-56 191.3 12.3 4.5e-56 190.4 12.3 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO19751.1 - 0.00082 18.3 2.0 0.033 13.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family CMAS PF02353.20 KDO19752.1 - 7.3e-08 32.0 0.1 1.5e-07 31.0 0.0 1.5 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Anoctamin PF04547.12 KDO19752.1 - 0.049 12.5 0.0 0.049 12.5 0.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel Stealth_CR2 PF11380.8 KDO19754.1 - 5.5e-43 145.5 0.0 1.7e-41 140.8 0.0 2.5 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KDO19754.1 - 8.7e-16 57.6 4.9 2.7e-15 56.0 4.9 1.9 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 KDO19754.1 - 7.4e-13 48.0 2.6 7.4e-13 48.0 2.6 2.1 2 0 0 2 2 2 1 Stealth protein CR1, conserved region 1 Notch PF00066.17 KDO19754.1 - 4.8e-12 46.1 28.9 1.1e-06 29.0 7.9 2.6 2 0 0 2 2 2 2 LNR domain Stealth_CR4 PF17103.5 KDO19754.1 - 1.1e-10 41.2 0.1 2.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 RNase_T PF00929.24 KDO19755.1 - 4.1e-07 30.7 0.0 1.1e-06 29.3 0.0 1.8 1 1 0 1 1 1 1 Exonuclease Leo1 PF04004.13 KDO19756.1 - 7.3e-34 117.0 0.1 7.3e-34 117.0 0.1 1.7 2 0 0 2 2 2 1 Leo1-like protein LTXXQ PF07813.12 KDO19756.1 - 0.8 10.5 7.0 0.13 13.0 0.9 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein DUF3245 PF11595.8 KDO19756.1 - 3.3 8.2 12.1 0.33 11.4 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) ATG16 PF08614.11 KDO19757.1 - 0.0047 17.2 14.4 0.0047 17.2 14.4 2.8 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 KDO19757.1 - 0.022 14.0 30.1 0.055 12.7 30.1 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region HALZ PF02183.18 KDO19757.1 - 0.36 11.1 12.7 1.9 8.8 0.9 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper UPF0242 PF06785.11 KDO19757.1 - 0.96 9.5 30.8 0.62 10.1 11.1 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KDO19757.1 - 3.4 5.4 11.7 1.8 6.4 9.3 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3138 PF11336.8 KDO19757.1 - 8.1 4.9 9.0 3.5 6.1 5.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3138) Jnk-SapK_ap_N PF09744.9 KDO19757.1 - 10 6.4 34.0 0.78 9.9 8.3 3.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Ras PF00071.22 KDO19758.1 - 2e-47 160.8 0.1 2.5e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO19758.1 - 1.5e-20 73.6 0.1 2e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO19758.1 - 2.5e-10 40.1 0.2 3e-10 39.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KDO19758.1 - 0.0003 20.7 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO19758.1 - 0.00034 20.2 0.2 0.0017 17.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO19758.1 - 0.00095 19.2 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KDO19758.1 - 0.024 13.9 0.1 0.13 11.5 0.0 2.0 2 1 0 2 2 2 0 Septin G-alpha PF00503.20 KDO19758.1 - 0.046 12.9 0.1 5.1 6.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KDO19758.1 - 0.065 13.6 0.1 0.084 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KDO19758.1 - 0.13 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KDO19759.1 - 2.2e-63 214.1 0.0 3.4e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19759.1 - 1.1e-45 156.0 0.0 1.7e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF547 PF04784.14 KDO19759.1 - 4.3e-21 75.2 0.0 7.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Response_reg PF00072.24 KDO19759.1 - 3.5e-20 72.2 0.3 7.6e-20 71.2 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KDO19759.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO19759.1 - 0.055 12.2 0.0 0.12 11.1 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase zf-RING_2 PF13639.6 KDO19760.1 - 2.2e-10 40.7 5.0 2.2e-10 40.7 5.0 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO19760.1 - 1.1e-08 34.7 2.5 1.1e-08 34.7 2.5 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO19760.1 - 2.1e-08 33.9 4.9 2.1e-08 33.9 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO19760.1 - 8.6e-07 28.7 3.2 1.7e-06 27.8 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO19760.1 - 4.9e-06 26.7 7.5 1.7e-05 25.0 7.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO19760.1 - 4e-05 23.5 2.5 7e-05 22.7 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO19760.1 - 0.00034 20.6 0.3 0.00034 20.6 0.3 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO19760.1 - 0.00062 19.6 2.1 0.0014 18.4 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO19760.1 - 0.0061 16.4 4.9 0.016 15.1 4.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO19760.1 - 0.059 13.4 0.9 0.15 12.1 0.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ComFB PF10719.9 KDO19760.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Late competence development protein ComFB Zn_ribbon_17 PF17120.5 KDO19760.1 - 0.24 11.1 2.8 0.44 10.2 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KDO19760.1 - 1.5 9.0 5.3 2 8.6 3.6 2.1 2 1 0 2 2 2 0 RING-variant domain Pkinase PF00069.25 KDO19761.1 - 1.7e-45 155.5 0.0 2.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19761.1 - 3.5e-14 52.7 0.0 5.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO19761.1 - 0.00014 21.8 0.0 0.005 16.8 0.0 2.6 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO19761.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO19761.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KDO19761.1 - 0.14 11.7 0.1 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Cwf_Cwc_15 PF04889.12 KDO19761.1 - 0.16 11.7 12.6 0.34 10.6 12.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KDO19761.1 - 7.5 5.9 8.1 10 5.4 8.1 1.1 1 0 0 1 1 1 0 SDA1 PCI PF01399.27 KDO19762.1 - 3.5e-12 46.7 1.2 1e-11 45.2 1.2 1.8 1 0 0 1 1 1 1 PCI domain NUDIX PF00293.28 KDO19763.1 - 1.3e-06 28.4 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Anoctamin PF04547.12 KDO19764.1 - 4.5e-101 338.9 3.1 5.6e-101 338.6 3.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF5455 PF17537.2 KDO19764.1 - 0.16 12.4 3.8 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5455) CTD_bind PF04818.13 KDO19765.1 - 1.4e-05 25.8 0.0 3.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Fib_alpha PF08702.10 KDO19765.1 - 0.25 11.5 3.1 0.22 11.7 0.5 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DZR PF12773.7 KDO19766.1 - 9.7e-06 25.5 5.3 9.7e-06 25.5 5.3 2.5 1 1 0 2 2 2 2 Double zinc ribbon HHH_3 PF12836.7 KDO19767.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 KDO19767.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K AMP-binding PF00501.28 KDO19768.1 - 8.4e-86 288.2 0.0 1.2e-85 287.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 KDO19768.1 - 0.094 12.8 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) AMP-binding PF00501.28 KDO19769.1 - 3.5e-84 282.9 0.0 4.4e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme START PF01852.19 KDO19770.1 - 6.5e-21 74.7 0.0 3.3e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 START domain PH PF00169.29 KDO19770.1 - 1.7e-08 34.9 0.0 4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO19770.1 - 0.0056 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Aminotran_1_2 PF00155.21 KDO19773.1 - 4.2e-54 184.1 0.0 4.9e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KDO19773.1 - 0.00016 20.3 0.0 0.00024 19.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Abhydrolase_9_N PF15420.6 KDO19774.1 - 0.091 12.8 3.1 0.2 11.6 0.8 1.9 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Ank_2 PF12796.7 KDO19776.1 - 5.5e-75 248.0 62.6 1.3e-13 51.3 0.4 8.4 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19776.1 - 4.6e-43 145.0 31.2 1.6e-06 28.5 0.1 11.3 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19776.1 - 6e-40 130.7 39.4 0.00023 21.3 0.1 15.8 16 0 0 16 16 16 9 Ankyrin repeat Ank_5 PF13857.6 KDO19776.1 - 1.4e-38 130.5 38.0 1e-06 28.9 0.5 11.9 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 KDO19776.1 - 1.8e-30 104.0 53.8 0.00061 20.1 0.3 14.0 16 0 0 16 16 16 10 Ankyrin repeat VWA_3_C PF18571.1 KDO19776.1 - 2.5 8.1 5.2 5 7.1 0.2 3.7 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 KDO19777.1 - 2.8e-31 107.9 5.2 3.4e-12 46.8 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19777.1 - 6e-29 100.1 9.8 9.6e-09 35.6 0.2 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19777.1 - 1.2e-27 95.6 8.7 3.1e-08 33.7 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19777.1 - 1.2e-24 83.7 7.7 4.5e-05 23.5 0.0 7.0 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KDO19777.1 - 3.2e-19 68.5 10.4 0.0023 18.3 0.2 7.0 7 0 0 7 7 7 6 Ankyrin repeat SDF PF00375.18 KDO19778.1 - 2.4e-52 178.3 32.0 1.7e-51 175.5 32.0 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4501 PF14946.6 KDO19778.1 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Fascin PF06268.13 KDO19778.1 - 0.049 13.9 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Fascin domain Inositol_P PF00459.25 KDO19779.1 - 2e-11 43.9 0.0 4e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Agenet PF05641.12 KDO19780.1 - 3.1e-10 40.3 7.1 0.066 13.7 0.2 5.8 6 0 0 6 6 6 3 Agenet domain DUF4537 PF15057.6 KDO19780.1 - 7.3e-05 22.8 0.7 0.044 13.8 0.1 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4537) SMN PF06003.12 KDO19780.1 - 0.047 13.0 0.0 1.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) DUF4314 PF14192.6 KDO19780.1 - 0.17 11.9 0.5 0.82 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) Tcp10_C PF07202.13 KDO19780.1 - 0.19 11.7 1.1 0.99 9.3 0.1 2.6 3 0 0 3 3 3 0 T-complex protein 10 C-terminus SseC PF04888.12 KDO19780.1 - 6.6 6.2 6.7 12 5.4 6.7 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Arf PF00025.21 KDO19781.1 - 1.2e-13 50.8 0.0 2.9e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO19781.1 - 3e-07 29.9 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KDO19781.1 - 4.9e-05 22.8 0.0 7.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO19781.1 - 0.0039 17.2 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO19781.1 - 0.0079 15.6 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KDO19781.1 - 0.046 14.1 0.1 0.083 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KDO19781.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Acyl_transf_3 PF01757.22 KDO19783.1 - 5.1e-14 52.1 24.8 7e-08 31.9 7.8 2.6 2 1 1 3 3 3 2 Acyltransferase family DUF3899 PF13038.6 KDO19783.1 - 0.12 12.9 1.2 9.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) MerC PF03203.14 KDO19783.1 - 0.8 10.2 6.4 0.7 10.4 0.2 2.6 2 0 0 2 2 2 0 MerC mercury resistance protein Acyl_transf_3 PF01757.22 KDO19784.1 - 1.6e-21 76.7 32.8 2.4e-21 76.2 32.8 1.2 1 0 0 1 1 1 1 Acyltransferase family ERbeta_N PF12497.8 KDO19785.1 - 0.12 12.1 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Estrogen receptor beta Glyco_hydro_16 PF00722.21 KDO19786.1 - 4.8e-24 84.8 8.0 1.8e-11 43.9 0.5 4.4 3 2 0 3 3 3 3 Glycosyl hydrolases family 16 Elicitin PF00964.17 KDO19787.1 - 0.0017 18.4 2.1 0.0017 18.4 2.1 2.0 1 1 1 2 2 2 1 Elicitin Trypsin_2 PF13365.6 KDO19788.1 - 1.1e-08 36.1 0.0 2.6e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain WW PF00397.26 KDO19788.1 - 0.051 13.7 8.1 0.093 12.8 2.2 2.6 2 0 0 2 2 2 0 WW domain IQ PF00612.27 KDO19788.1 - 0.052 13.4 11.7 0.42 10.5 0.6 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif MCD_N PF17408.2 KDO19788.1 - 0.056 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Elicitin PF00964.17 KDO19789.1 - 2.4e-08 34.0 0.5 0.00029 20.9 0.1 2.4 2 0 0 2 2 2 2 Elicitin Trp_oprn_chp PF09534.10 KDO19789.1 - 0.019 14.8 3.9 0.019 14.8 3.9 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1206 PF06724.11 KDO19789.1 - 0.076 13.1 4.2 0.16 12.0 4.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Saf_2TM PF18303.1 KDO19789.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain CcmD PF04995.14 KDO19789.1 - 0.33 11.1 2.7 0.7 10.0 2.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TMEM51 PF15345.6 KDO19789.1 - 0.38 10.6 4.4 1.5 8.6 0.3 2.7 2 1 1 3 3 3 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 KDO19789.1 - 2.4 8.2 6.0 0.56 10.2 0.2 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Secretin_N_2 PF07655.13 KDO19789.1 - 5.7 7.6 16.7 0.28 11.8 9.0 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain TRAM_LAG1_CLN8 PF03798.16 KDO19790.1 - 4.1e-19 69.1 16.5 4.1e-19 69.1 16.5 1.5 2 0 0 2 2 2 1 TLC domain zf-RanBP PF00641.18 KDO19792.1 - 0.042 13.2 1.3 0.042 13.2 1.3 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Tnp_zf-ribbon_2 PF13842.6 KDO19792.1 - 1.6 9.6 19.0 0.14 13.0 9.9 2.8 2 2 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PIG-Y PF15159.6 KDO19795.1 - 1e-20 74.4 1.6 1.3e-20 74.1 1.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Pkinase PF00069.25 KDO19796.1 - 7.8e-14 51.7 0.0 8.6e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19796.1 - 1.4e-13 50.8 0.0 1.4e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO19796.1 - 0.0043 17.0 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19796.1 - 0.019 13.9 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Fructosamin_kin PF03881.14 KDO19796.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 KDO19797.1 - 0.025 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Zn_Tnp_IS1595 PF12760.7 KDO19797.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Pkinase_Tyr PF07714.17 KDO19798.1 - 1.4e-26 93.4 0.0 2.3e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19798.1 - 4.4e-24 85.3 0.0 6.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO19798.1 - 1.5e-05 25.0 0.1 0.011 15.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO19798.1 - 0.024 13.6 0.0 0.053 12.5 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Cupin_5 PF06172.11 KDO19799.1 - 3.4e-27 95.3 0.0 4.7e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Pkinase PF00069.25 KDO19799.1 - 1.3e-10 41.1 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19799.1 - 6e-09 35.6 0.0 8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Elicitin PF00964.17 KDO19800.1 - 7.6e-06 25.9 0.3 2.1e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Elicitin DUF5325 PF17259.2 KDO19800.1 - 0.086 12.7 2.2 0.25 11.2 2.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Elicitin PF00964.17 KDO19801.1 - 2.5e-07 30.7 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO19802.1 - 1.5e-05 25.0 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO19803.1 - 0.00032 20.7 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO19804.1 - 0.03 14.4 0.1 0.093 12.8 0.1 1.8 1 1 1 2 2 2 0 Elicitin Peptidase_M14 PF00246.24 KDO19805.1 - 5.3e-06 26.4 0.0 6.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Reo_sigmaC PF04582.12 KDO19805.1 - 0.12 12.7 0.1 0.25 11.6 0.0 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain Phage_integrase PF00589.22 KDO19806.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUF3523 PF12037.8 KDO19807.1 - 3.2e-41 141.5 18.4 4.8e-41 140.9 18.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KDO19807.1 - 2.7e-21 76.4 0.0 8.9e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO19807.1 - 1.2e-05 25.2 0.0 3.4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KDO19807.1 - 2.7e-05 24.4 0.0 0.0049 17.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KDO19807.1 - 9.7e-05 21.8 0.1 0.00023 20.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO19807.1 - 0.00025 21.0 0.2 0.0024 17.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO19807.1 - 0.0025 18.2 10.4 0.008 16.6 0.0 3.7 2 2 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 KDO19807.1 - 0.0026 17.4 3.0 0.21 11.1 0.0 3.0 2 2 1 3 3 3 1 AAA domain MRF_C1 PF13887.6 KDO19807.1 - 0.0053 15.9 0.0 0.017 14.3 0.0 1.9 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Zot PF05707.12 KDO19807.1 - 0.0061 16.2 0.8 0.22 11.1 0.0 3.0 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_3 PF07726.11 KDO19807.1 - 0.0085 16.0 0.0 0.039 13.8 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KDO19807.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO19807.1 - 0.015 15.8 0.4 0.1 13.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KDO19807.1 - 0.057 13.4 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KDO19807.1 - 0.059 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO19807.1 - 0.2 12.1 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KDO19807.1 - 0.21 12.0 0.2 0.21 12.0 0.2 3.5 3 1 1 5 5 4 0 AAA domain AAA_11 PF13086.6 KDO19807.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.7 2 1 0 2 2 1 0 AAA domain DUF2259 PF10016.9 KDO19807.1 - 2.2 8.2 8.6 11 5.9 7.5 2.3 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) 2OG-FeII_Oxy_3 PF13640.6 KDO19808.1 - 1.8e-15 57.6 0.1 3.1e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KDO19809.1 - 4.8e-14 53.0 0.0 9.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M14 PF00246.24 KDO19810.1 - 1.4e-37 130.1 0.0 1.8e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ACC_epsilon PF13822.6 KDO19810.1 - 3.8 8.3 5.3 0.6 10.8 1.2 1.8 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Aminotran_5 PF00266.19 KDO19811.1 - 1.4e-13 50.5 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KDO19811.1 - 0.00012 20.8 0.0 0.0002 20.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2154 PF09922.9 KDO19812.1 - 2e-05 24.4 0.2 4.4e-05 23.3 0.2 1.6 1 1 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF RCC1 PF00415.18 KDO19813.1 - 6.6e-48 161.1 15.6 4.1e-12 46.5 0.1 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO19813.1 - 1.9e-28 97.6 46.2 1.4e-07 31.1 0.3 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat VPS9 PF02204.18 KDO19813.1 - 0.00027 21.1 0.0 0.00049 20.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain NitrOD5 PF11537.8 KDO19817.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 PUL PF08324.11 KDO19819.1 - 3.1e-34 118.5 4.3 5.1e-34 117.8 4.3 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KDO19819.1 - 5e-22 78.3 0.0 9.4e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KDO19819.1 - 3e-17 62.7 17.4 0.00024 21.8 1.3 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Got1 PF04178.12 KDO19820.1 - 2.6e-28 98.7 18.3 3e-28 98.5 17.4 1.5 1 1 1 2 2 2 2 Got1/Sft2-like family COX15-CtaA PF02628.15 KDO19820.1 - 0.0035 16.5 7.0 0.0035 16.5 7.0 1.3 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein YfhO PF09586.10 KDO19820.1 - 0.63 8.2 8.6 0.74 8.0 8.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Tweety PF04906.13 KDO19820.1 - 2.1 6.9 7.6 1.1 7.8 3.7 1.9 2 0 0 2 2 2 0 Tweety EamA PF00892.20 KDO19824.1 - 0.0006 20.0 4.7 0.00074 19.7 4.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family EamA PF00892.20 KDO19825.1 - 1e-17 64.6 36.7 3.7e-11 43.3 18.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO19825.1 - 0.0002 20.8 1.5 0.0002 20.8 1.5 2.2 1 1 1 2 2 2 1 Triose-phosphate Transporter family Ank_4 PF13637.6 KDO19827.1 - 1.1e-18 67.4 0.0 5.7e-08 33.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19827.1 - 3.8e-17 62.1 0.0 2.4e-05 24.5 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19827.1 - 8.6e-17 61.5 0.0 5.7e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19827.1 - 1.3e-13 49.8 0.1 3.1e-05 24.0 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO19827.1 - 1.6e-13 50.4 0.2 0.00075 19.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat XOO_2897-deam PF14440.6 KDO19828.1 - 0.16 12.1 4.4 0.41 10.8 0.3 2.5 1 1 2 3 3 3 0 Xanthomonas XOO_2897-like deaminase Iso_dh PF00180.20 KDO19828.1 - 0.54 9.3 2.4 0.62 9.2 2.4 1.1 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Glutaredoxin2_C PF04399.13 KDO19828.1 - 0.84 9.5 6.1 0.29 11.0 1.1 2.2 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain IPK PF03770.16 KDO19828.1 - 1.1 9.1 5.0 1.4 8.8 5.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase USP8_interact PF08941.10 KDO19828.1 - 4 7.2 6.5 0.5 10.2 0.9 2.1 1 1 0 2 2 2 0 USP8 interacting Coq4 PF05019.13 KDO19829.1 - 2.7e-85 285.2 0.0 3.1e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Methyltransf_16 PF10294.9 KDO19830.1 - 1.5e-16 60.6 0.0 2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KDO19830.1 - 5.6e-07 29.5 0.0 7.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO19830.1 - 8.9e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO19830.1 - 0.00036 20.1 0.0 0.00053 19.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KDO19830.1 - 0.00052 19.8 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO19830.1 - 0.0037 17.9 0.0 0.0094 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO19830.1 - 0.011 16.4 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KDO19830.1 - 0.011 16.4 0.1 0.036 14.8 0.1 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.17 KDO19830.1 - 0.033 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Mob1_phocein PF03637.17 KDO19831.1 - 0.018 15.0 3.9 0.32 11.0 0.5 2.1 1 1 1 2 2 2 0 Mob1/phocein family FH2 PF02181.23 KDO19832.1 - 1.9e-63 214.8 0.0 7.1e-63 213.0 0.0 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 KDO19832.1 - 1.6e-23 83.8 9.8 6.3e-07 29.9 0.2 4.0 1 1 2 3 3 3 3 Subunit CCDC53 of WASH complex Drf_GBD PF06371.13 KDO19832.1 - 8e-23 81.0 0.1 2.6e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KDO19832.1 - 1.5e-10 41.0 0.0 5.4e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Diaphanous FH3 Domain SesA PF17107.5 KDO19832.1 - 0.013 15.6 0.6 12 6.1 0.1 3.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1192 PF06698.11 KDO19832.1 - 0.028 14.4 4.1 0.11 12.6 4.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Sec2p PF06428.11 KDO19832.1 - 0.061 13.3 1.6 0.11 12.5 0.3 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Lzipper-MIP1 PF14389.6 KDO19832.1 - 0.07 13.4 0.3 0.27 11.6 0.3 2.1 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 ABC_tran_CTD PF16326.5 KDO19832.1 - 0.11 12.8 2.2 1.3 9.3 0.9 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Phage_GPO PF05929.11 KDO19832.1 - 1.4 8.5 5.2 16 5.0 0.1 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3618 PF12277.8 KDO19832.1 - 1.5 9.1 5.6 1.2 9.5 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) ABC_tran PF00005.27 KDO19833.1 - 7.2e-58 195.0 0.0 2.3e-29 102.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO19833.1 - 9e-34 117.1 45.8 2.3e-20 73.0 11.7 4.1 3 1 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO19833.1 - 1.6e-19 70.9 0.2 3.5e-06 27.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO19833.1 - 9e-06 25.6 0.0 0.069 12.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.6 KDO19833.1 - 0.0018 18.5 0.1 4.7 7.5 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KDO19833.1 - 0.0024 17.5 2.2 0.12 12.1 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO19833.1 - 0.0034 17.9 2.8 0.22 12.0 0.2 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO19833.1 - 0.0079 15.7 0.0 6.9 6.0 0.0 3.4 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO19833.1 - 0.013 15.4 0.1 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF4162 PF13732.6 KDO19833.1 - 0.084 13.6 0.0 2.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DUF4690 PF15756.5 KDO19833.1 - 0.13 12.9 1.9 0.4 11.3 1.9 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Zeta_toxin PF06414.12 KDO19833.1 - 0.24 10.6 0.3 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KDO19833.1 - 0.34 10.5 3.4 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5373 PF17343.2 KDO19833.1 - 0.36 10.7 0.0 0.36 10.7 0.0 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5373) MukB PF04310.12 KDO19833.1 - 0.44 10.3 2.0 9.7 5.9 0.3 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_30 PF13604.6 KDO19833.1 - 0.58 9.8 3.4 18 5.0 0.7 2.8 2 1 1 3 3 3 0 AAA domain ABC2_membrane_2 PF12679.7 KDO19833.1 - 1.8 7.8 26.3 0.28 10.4 10.6 3.7 3 1 0 4 4 4 0 ABC-2 family transporter protein MFS_1 PF07690.16 KDO19834.1 - 0.13 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily ABC_tran PF00005.27 KDO19835.1 - 8.6e-58 194.7 0.0 2.3e-29 102.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO19835.1 - 7.3e-37 127.3 38.2 4.4e-22 78.7 12.3 3.5 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO19835.1 - 1.5e-19 70.9 0.2 3.4e-06 27.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO19835.1 - 8.5e-06 25.7 0.0 0.068 12.9 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.6 KDO19835.1 - 0.0019 18.4 0.1 4.7 7.5 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KDO19835.1 - 0.0026 17.5 2.2 0.12 12.1 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO19835.1 - 0.0032 18.0 2.8 0.21 12.0 0.2 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO19835.1 - 0.0073 15.8 0.0 6.9 6.0 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain PspB PF06667.12 KDO19835.1 - 0.0088 16.1 0.0 0.032 14.3 0.0 2.0 1 0 0 1 1 1 1 Phage shock protein B RsgA_GTPase PF03193.16 KDO19835.1 - 0.03 14.2 0.5 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KDO19835.1 - 0.24 10.6 0.3 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KDO19835.1 - 0.34 10.5 3.4 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 KDO19835.1 - 0.43 10.3 2.0 9.6 5.9 0.3 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_30 PF13604.6 KDO19835.1 - 0.56 9.9 3.4 17 5.0 0.7 2.8 2 1 1 3 3 3 0 AAA domain ABC2_membrane_2 PF12679.7 KDO19835.1 - 1.9 7.7 23.1 0.0092 15.3 9.8 3.0 2 1 1 3 3 3 0 ABC-2 family transporter protein Ank_2 PF12796.7 KDO19836.1 - 1.7e-11 44.6 11.2 2.1e-06 28.2 0.7 3.3 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19836.1 - 0.00042 20.8 5.0 0.0066 17.0 0.1 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19836.1 - 0.00098 19.4 5.6 8.5 6.8 0.1 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19836.1 - 0.0013 19.0 5.5 19 6.3 0.0 5.7 7 0 0 7 7 7 2 Ankyrin repeat Toxin_14 PF07829.11 KDO19836.1 - 0.083 12.8 0.5 0.21 11.6 0.5 1.6 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein Coat_F PF07875.12 KDO19836.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Coat F domain CDC45 PF02724.14 KDO19837.1 - 0.5 8.6 10.4 0.71 8.1 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein cNMP_binding PF00027.29 KDO19838.1 - 7.6e-42 141.3 0.1 3.3e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CE2_N PF17996.1 KDO19840.1 - 2.9e-11 43.3 0.0 8.8e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 KDO19840.1 - 2.3e-10 41.2 0.0 3.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO19840.1 - 0.055 13.4 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_hydro_85 PF03644.13 KDO19841.1 - 7.9e-09 35.4 0.1 1.6e-08 34.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 MR_MLE_C PF13378.6 KDO19841.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like Gal-3-0_sulfotr PF06990.11 KDO19841.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Spore_permease PF03845.13 KDO19841.1 - 0.16 10.8 0.4 0.28 10.0 0.4 1.3 1 0 0 1 1 1 0 Spore germination protein TackOD1 PF18551.1 KDO19842.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-Di19 PF05605.12 KDO19842.1 - 0.028 14.7 0.1 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KDO19842.1 - 0.088 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Abhydrolase_1 PF00561.20 KDO19843.1 - 2.4e-06 27.4 0.0 3.5e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO19843.1 - 0.0008 18.7 0.0 0.0062 15.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PDZ PF00595.24 KDO19844.1 - 2.6e-12 46.9 0.0 0.0072 16.7 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PA PF02225.22 KDO19844.1 - 1.2e-10 41.2 0.0 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 2 PA domain PDZ_6 PF17820.1 KDO19844.1 - 3.9e-08 33.0 0.1 0.016 15.0 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KDO19844.1 - 8.3e-07 29.2 0.4 0.013 15.8 0.0 4.1 4 0 0 4 4 4 1 PDZ domain Ank_2 PF12796.7 KDO19845.1 - 1.6e-17 63.9 0.3 8.4e-07 29.5 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19845.1 - 6.5e-10 38.4 1.7 1.9 9.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KDO19845.1 - 1.1e-05 25.9 0.1 0.0083 16.7 0.0 4.2 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO19845.1 - 0.00027 21.2 1.8 3.6 8.2 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KDO19845.1 - 0.00075 19.7 1.3 6.2 7.3 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19846.1 - 1.5e-16 60.7 0.0 0.00016 22.2 0.0 5.4 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19846.1 - 1.7e-09 38.0 1.4 0.1 13.2 0.0 5.9 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO19846.1 - 3e-08 33.3 5.1 1.3 9.8 0.0 8.3 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KDO19846.1 - 8.1e-06 26.0 0.7 0.48 10.8 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO19846.1 - 6.5e-05 23.2 8.6 5.5 7.6 0.1 6.9 8 0 0 8 8 8 2 Ankyrin repeat THF_DHG_CYH_C PF02882.19 KDO19847.1 - 5.1e-61 204.7 0.6 7.5e-61 204.1 0.6 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KDO19847.1 - 1.3e-34 118.9 0.1 1.8e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain p25-alpha PF05517.12 KDO19848.1 - 1.1e-09 38.6 1.7 1.6e-05 25.1 0.0 3.2 2 1 0 2 2 2 2 p25-alpha CH PF00307.31 KDO19848.1 - 1.1e-05 25.5 0.0 3.9e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Spc29 PF17082.5 KDO19848.1 - 0.0023 17.8 0.1 0.0088 15.9 0.1 2.0 1 0 0 1 1 1 1 Spindle Pole Component 29 CH_2 PF06294.11 KDO19848.1 - 0.017 15.2 0.0 0.071 13.2 0.0 2.1 1 0 0 1 1 1 0 CH-like domain in sperm protein ZapB PF06005.12 KDO19848.1 - 0.066 13.7 6.0 0.086 13.3 0.0 3.8 5 0 0 5 5 5 0 Cell division protein ZapB RPN13_C PF16550.5 KDO19848.1 - 0.12 12.5 0.5 1 9.6 0.1 2.6 2 0 0 2 2 2 0 UCH-binding domain BLOC1_2 PF10046.9 KDO19848.1 - 0.15 12.3 4.4 0.13 12.6 1.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KDO19848.1 - 0.3 11.7 3.6 24 5.6 0.2 4.0 3 0 0 3 3 3 0 SlyX DUF4795 PF16043.5 KDO19848.1 - 0.61 9.7 5.6 2.8 7.5 3.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 KDO19848.1 - 1.4 9.1 9.9 0.026 14.8 1.6 2.4 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KDO19848.1 - 2 8.6 7.1 0.13 12.4 0.2 2.7 3 0 0 3 3 3 0 bZIP transcription factor F420_oxidored PF03807.17 KDO19849.1 - 1.1e-07 32.3 0.1 2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 KDO19849.1 - 2.9e-06 27.5 2.3 4.5e-06 26.8 0.4 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation TRC8_N PF13705.6 KDO19849.1 - 0.059 12.3 0.6 0.13 11.1 0.6 1.5 1 1 0 1 1 1 0 TRC8 N-terminal domain PHD PF00628.29 KDO19850.1 - 9.4e-12 44.6 23.8 8e-09 35.3 3.6 4.0 3 1 1 4 4 4 2 PHD-finger PWWP PF00855.17 KDO19850.1 - 1.3e-10 41.6 0.1 3.2e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H PF13771.6 KDO19850.1 - 0.00034 20.8 9.9 0.0054 17.0 0.7 3.4 4 0 0 4 4 4 2 PHD-like zinc-binding domain FANCL_C PF11793.8 KDO19850.1 - 0.0054 16.9 14.4 0.046 13.9 2.6 3.5 3 0 0 3 3 3 2 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 KDO19850.1 - 0.018 15.2 1.0 0.018 15.2 1.0 3.6 3 2 1 4 4 4 0 PHD-zinc-finger like domain zf-rbx1 PF12678.7 KDO19850.1 - 0.1 12.9 13.8 0.43 10.9 4.6 3.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain TylF PF05711.11 KDO19851.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Lipoprotein_16 PF03923.13 KDO19851.1 - 0.24 11.0 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized lipoprotein TLV_coat PF00429.19 KDO19852.1 - 0.015 14.0 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) TFIIS_M PF07500.14 KDO19853.1 - 2.4e-18 66.6 5.2 2.4e-18 66.6 5.2 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KDO19853.1 - 2.8e-17 62.3 3.8 4.6e-17 61.6 3.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KDO19853.1 - 9.1e-14 51.2 0.8 3.8e-13 49.2 0.8 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LEDGF PF11467.8 KDO19853.1 - 0.021 14.4 0.7 0.1 12.2 0.1 2.5 1 1 1 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) zf-DNL PF05180.12 KDO19853.1 - 0.022 14.7 1.0 0.055 13.4 1.0 1.7 1 0 0 1 1 1 0 DNL zinc finger zinc_ribbon_6 PF14599.6 KDO19853.1 - 4.7 7.3 7.8 5.4 7.1 0.3 3.2 3 0 0 3 3 3 0 Zinc-ribbon IF4E PF01652.18 KDO19856.1 - 1.4e-41 141.9 0.1 1.7e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_S9 PF00326.21 KDO19857.1 - 1.9e-40 138.6 0.0 2.8e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KDO19857.1 - 1.6e-10 40.9 0.4 1.6e-09 37.7 0.4 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KDO19857.1 - 2.4e-07 30.6 0.2 5.3e-07 29.5 0.2 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KDO19857.1 - 3.8e-07 30.2 2.9 3.1e-05 23.9 2.9 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KDO19857.1 - 4.2e-05 23.6 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 KDO19857.1 - 0.00016 21.1 1.5 0.00071 19.0 1.5 1.9 2 0 0 2 2 2 1 Secretory lipase Hydrolase_4 PF12146.8 KDO19857.1 - 0.00016 21.0 0.1 0.4 9.9 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KDO19857.1 - 0.0016 18.0 0.2 0.0026 17.3 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Gmad1 PF10647.9 KDO19857.1 - 0.005 16.6 0.2 2.7 7.7 0.3 2.5 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Abhydrolase_4 PF08386.10 KDO19857.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein AXE1 PF05448.12 KDO19857.1 - 0.069 11.8 0.1 0.17 10.5 0.1 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KDO19857.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Pox_MCEL PF03291.16 KDO19858.1 - 5.1e-43 147.5 0.0 1.9e-42 145.6 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KDO19858.1 - 2.2e-09 37.9 0.3 1.1e-07 32.5 0.3 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO19858.1 - 5.2e-08 33.5 0.0 1.6e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO19858.1 - 1.3e-07 31.5 0.0 3.3e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO19858.1 - 2e-05 25.2 0.1 0.0011 19.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO19858.1 - 0.00025 20.9 0.0 0.00068 19.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 KDO19858.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) WW PF00397.26 KDO19858.1 - 0.019 15.0 1.2 0.019 15.0 1.2 2.1 2 0 0 2 2 2 0 WW domain Methyltransf_4 PF02390.17 KDO19858.1 - 0.023 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Cache_3-Cache_2 PF17201.4 KDO19860.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain RabGAP-TBC PF00566.18 KDO19862.1 - 1.1e-11 44.8 2.2 1.7e-11 44.2 0.5 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 KDO19862.1 - 4e-09 36.9 0.1 0.25 12.3 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO19862.1 - 0.056 13.8 0.0 14 6.1 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Complex1_51K PF01512.17 KDO19863.1 - 1.3e-47 161.5 0.0 4.1e-47 159.9 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KDO19863.1 - 1.8e-28 98.4 0.1 3.4e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KDO19863.1 - 3.2e-09 36.5 0.0 6.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Exonuc_VII_S PF02609.16 KDO19863.1 - 0.74 9.9 1.8 2 8.6 0.4 2.4 2 1 1 3 3 3 0 Exonuclease VII small subunit DUF726 PF05277.12 KDO19864.1 - 4.2e-83 279.1 0.0 5.1e-69 232.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Thioesterase PF00975.20 KDO19864.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain FWWh PF14922.6 KDO19865.1 - 4.4e-33 114.3 0.5 5.9e-33 113.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function UQ_con PF00179.26 KDO19866.1 - 1e-32 112.7 0.0 1.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme B2-adapt-app_C PF09066.10 KDO19867.1 - 1e-09 38.5 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain CDC45 PF02724.14 KDO19867.1 - 0.076 11.3 3.9 0.15 10.4 3.9 1.4 1 0 0 1 1 1 0 CDC45-like protein XRCC4 PF06632.12 KDO19867.1 - 0.72 8.6 3.3 1.2 8.0 3.3 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DEAD PF00270.29 KDO19869.1 - 1.3e-36 126.0 0.0 1.8e-35 122.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO19869.1 - 7e-21 74.7 0.0 3.6e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO19869.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CH PF00307.31 KDO19870.1 - 1.5e-74 247.2 3.8 2.7e-19 69.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KDO19870.1 - 1.2e-12 48.0 0.1 4.1e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO19870.1 - 9.5e-12 43.6 0.1 3e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KDO19870.1 - 2.6e-11 43.2 1.6 1.7e-06 27.8 0.1 4.2 5 0 0 5 5 5 2 CAMSAP CH domain EF-hand_5 PF13202.6 KDO19870.1 - 1.1e-10 40.5 0.3 5e-06 25.8 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO19870.1 - 8.1e-09 34.7 0.3 1.6e-05 24.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO19870.1 - 3.4e-07 30.0 0.1 0.061 13.2 0.0 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO19870.1 - 0.00082 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO19870.1 - 0.0027 18.0 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region CH_2 PF06294.11 KDO19870.1 - 0.0065 16.6 0.2 10 6.3 0.0 3.6 4 0 0 4 4 4 2 CH-like domain in sperm protein DEAD PF00270.29 KDO19871.1 - 2.5e-46 157.6 0.0 4.9e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO19871.1 - 3.1e-25 88.7 0.1 1.2e-23 83.6 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 KDO19871.1 - 3.8e-22 78.4 0.0 1.2e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 KDO19871.1 - 2e-09 37.7 0.0 2e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KDO19871.1 - 0.0017 17.7 10.1 0.056 12.8 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 KDO19871.1 - 0.0084 15.8 0.2 0.036 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AP3D1 PF06375.11 KDO19871.1 - 0.34 11.1 17.0 0.64 10.2 17.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Spore_coat_CotO PF14153.6 KDO19871.1 - 1.6 8.6 11.2 3.3 7.6 11.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO ATG11 PF10377.9 KDO19871.1 - 2.4 8.3 9.3 13 5.9 0.0 2.7 2 1 0 2 2 2 0 Autophagy-related protein 11 SR-25 PF10500.9 KDO19871.1 - 2.8 7.5 18.1 4.6 6.8 18.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SWIRM-assoc_2 PF16496.5 KDO19871.1 - 3.7 6.3 13.5 2.6 6.8 11.2 1.7 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Peptidase_C1 PF00112.23 KDO19872.1 - 7.5e-41 140.6 0.1 9.8e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO19872.1 - 0.01 14.6 0.6 0.016 14.0 0.6 1.2 1 0 0 1 1 1 0 Peptidase C1-like family SNRNP27 PF08648.12 KDO19872.1 - 0.089 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Taxilin PF09728.9 KDO19874.1 - 0.0012 18.0 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein SHE3 PF17078.5 KDO19874.1 - 0.018 14.8 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 COG5 PF10392.9 KDO19874.1 - 0.034 14.3 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Spc29 PF17082.5 KDO19874.1 - 0.035 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Angiomotin_C PF12240.8 KDO19874.1 - 0.04 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Angiomotin C terminal DUF4795 PF16043.5 KDO19875.1 - 0.037 13.6 0.2 0.037 13.6 0.2 4.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) DUF4047 PF13256.6 KDO19875.1 - 0.038 14.2 0.6 0.038 14.2 0.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4047) SHE3 PF17078.5 KDO19875.1 - 0.11 12.3 0.1 0.11 12.3 0.1 4.2 4 0 0 4 4 4 0 SWI5-dependent HO expression protein 3 NPV_P10 PF05531.12 KDO19875.1 - 0.66 10.5 17.1 1.4 9.4 0.8 5.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 KDO19875.1 - 1.5 8.9 19.7 1.9 8.6 0.5 5.6 5 1 0 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 KDO19875.1 - 1.6 8.9 20.4 2.1 8.5 0.1 4.5 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 KDO19875.1 - 4 7.8 15.8 28 5.0 2.1 5.7 6 0 0 6 6 6 0 Homeobox associated leucine zipper Tup_N PF08581.10 KDO19875.1 - 4.6 7.6 13.7 29 5.1 1.4 4.8 4 1 0 4 4 4 0 Tup N-terminal Prenylcys_lyase PF07156.14 KDO19877.1 - 2.4e-81 273.7 0.0 3.5e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KDO19877.1 - 2.7e-19 69.8 0.6 9.5e-19 68.0 0.0 2.1 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KDO19877.1 - 2e-14 53.5 0.6 5.4e-14 52.2 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KDO19877.1 - 4e-07 30.0 2.1 2.2e-05 24.2 0.8 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO19877.1 - 5.6e-07 29.1 0.1 0.00075 18.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO19877.1 - 3.4e-05 24.3 0.2 0.019 15.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KDO19877.1 - 6.8e-05 22.3 0.1 0.00012 21.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KDO19877.1 - 0.00054 19.1 0.2 0.00088 18.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KDO19877.1 - 0.0068 16.4 0.1 3.4 7.6 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KDO19877.1 - 0.0075 15.0 0.1 0.99 8.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KDO19877.1 - 0.0094 15.0 0.1 2.5 7.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KDO19877.1 - 0.059 12.6 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KDO19877.1 - 0.1 11.9 0.1 3.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO19877.1 - 0.16 11.3 0.3 0.26 10.6 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KDO19877.1 - 0.22 11.4 0.3 0.72 9.7 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SHE3 PF17078.5 KDO19878.1 - 0.0052 16.5 3.0 0.0052 16.5 3.0 5.1 2 2 1 4 4 4 2 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 KDO19878.1 - 0.023 14.7 0.1 0.023 14.7 0.1 7.0 3 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KDO19878.1 - 0.079 12.3 51.5 0.64 9.3 3.9 5.9 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding MPS2 PF17060.5 KDO19878.1 - 6.5 5.9 23.1 1.3 8.2 4.2 4.4 2 1 2 5 5 5 0 Monopolar spindle protein 2 RicinB_lectin_2 PF14200.6 KDO19879.1 - 8.4e-07 29.6 8.0 0.17 12.6 0.0 5.0 1 1 5 6 6 6 4 Ricin-type beta-trefoil lectin domain-like PUA_3 PF17785.1 KDO19879.1 - 0.041 13.7 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 PUA-like domain TonB_2 PF13103.6 KDO19879.1 - 0.099 12.9 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 TonB C terminal PhnA_Zn_Ribbon PF08274.12 KDO19879.1 - 1.4 9.0 8.3 18 5.4 0.1 4.1 5 0 0 5 5 5 0 PhnA Zinc-Ribbon DUF1765 PF08578.10 KDO19881.1 - 9.8e-08 32.5 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) WD40 PF00400.32 KDO19882.1 - 3.1e-16 59.4 12.3 1.5e-07 32.0 0.4 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO19882.1 - 1.3e-06 28.6 0.0 3 8.2 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPIP1 PF15338.6 KDO19882.1 - 0.027 14.5 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Prot_ATP_ID_OB PF16450.5 KDO19882.1 - 0.038 14.0 0.2 0.092 12.7 0.2 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Beach PF02138.18 KDO19882.1 - 0.24 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Ion_trans PF00520.31 KDO19883.1 - 1.4e-19 70.3 21.4 2.2e-19 69.7 21.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO19883.1 - 2e-11 43.7 4.2 2e-11 43.7 4.2 3.0 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 KDO19883.1 - 0.00035 20.6 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PSGP PF07276.11 KDO19883.1 - 3.2 8.3 5.0 21 5.8 0.7 2.8 2 0 0 2 2 2 0 Apopolysialoglycoprotein (PSGP) LRR_4 PF12799.7 KDO19886.1 - 0.018 15.5 2.5 1.5 9.4 0.0 4.2 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) p450 PF00067.22 KDO19887.1 - 6.7e-81 272.4 0.0 8.1e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Es2 PF09751.9 KDO19888.1 - 2.1e-53 182.6 14.1 1.8e-44 153.2 7.7 2.3 1 1 1 2 2 2 2 Nuclear protein Es2 Tim44 PF04280.15 KDO19889.1 - 3.7e-06 27.1 1.8 3.7e-05 23.9 1.8 2.2 1 1 0 1 1 1 1 Tim44-like domain Arteri_nsp7a PF16749.5 KDO19890.1 - 0.033 14.4 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha LURAP PF14854.6 KDO19890.1 - 0.14 12.2 0.8 0.2 11.6 0.8 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein Pkinase_Tyr PF07714.17 KDO19891.1 - 2.4e-44 151.6 0.0 3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19891.1 - 2.4e-40 138.6 0.0 3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GcpE PF04551.14 KDO19891.1 - 0.015 14.4 0.0 0.061 12.4 0.0 1.8 2 0 0 2 2 2 0 GcpE protein Pkinase_fungal PF17667.1 KDO19891.1 - 0.027 13.2 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO19891.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aminotran_4 PF01063.19 KDO19891.1 - 0.072 12.9 0.1 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 Amino-transferase class IV Haspin_kinase PF12330.8 KDO19891.1 - 0.094 11.6 0.0 0.47 9.3 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain PX PF00787.24 KDO19892.1 - 2.4e-10 40.4 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 PX domain CBS PF00571.28 KDO19895.1 - 1.1e-22 80.2 0.7 2.8e-06 27.7 0.3 4.4 4 0 0 4 4 4 4 CBS domain PX PF00787.24 KDO19896.1 - 4.2e-09 36.4 0.0 7.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 PX domain CPSase_L_D2 PF02786.17 KDO19898.1 - 1.6e-104 348.0 0.2 4.1e-81 271.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KDO19898.1 - 2.9e-49 166.1 0.0 6e-49 165.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KDO19898.1 - 8.2e-47 159.4 0.0 7.7e-46 156.3 0.0 2.5 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KDO19898.1 - 2e-39 134.7 0.1 3.9e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KDO19898.1 - 1.8e-18 66.5 0.0 5.6e-17 61.7 0.0 3.2 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.22 KDO19898.1 - 7.1e-15 55.0 0.1 5.7e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KDO19898.1 - 9.2e-14 51.3 0.1 1e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KDO19898.1 - 2e-10 40.5 0.1 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 KDO19898.1 - 0.00018 21.3 1.1 0.027 14.2 1.1 2.3 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 KDO19898.1 - 0.00053 19.8 0.1 0.058 13.2 0.0 2.9 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KDO19898.1 - 0.0019 18.3 0.4 1 9.4 0.0 3.1 3 0 0 3 3 3 1 ATP-grasp domain DJ-1_PfpI PF01965.24 KDO19898.1 - 0.0032 17.3 0.1 0.73 9.6 0.0 3.1 3 0 0 3 3 3 1 DJ-1/PfpI family ATP-grasp_5 PF13549.6 KDO19898.1 - 0.035 13.6 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain TrkA_N PF02254.18 KDO19898.1 - 0.04 14.2 0.1 14 6.0 0.0 2.9 2 0 0 2 2 2 0 TrkA-N domain B12-binding PF02310.19 KDO19898.1 - 0.1 12.6 0.0 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 B12 binding domain Pkinase PF00069.25 KDO19899.1 - 2e-50 171.6 0.0 2.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19899.1 - 2.8e-31 108.8 0.0 1.8e-30 106.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19899.1 - 0.00014 21.2 0.3 0.00093 18.6 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO19899.1 - 0.00035 19.5 0.3 0.0011 17.8 0.1 1.6 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KDO19899.1 - 0.00075 19.5 1.3 0.0019 18.1 0.6 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO19899.1 - 0.019 14.3 0.3 0.051 12.9 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4PPT_N PF17837.1 KDO19899.1 - 0.033 14.3 0.1 0.091 12.9 0.1 1.7 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain YrbL-PhoP_reg PF10707.9 KDO19899.1 - 0.073 12.6 0.4 2 7.9 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SPATA9 PF15824.5 KDO19900.1 - 0.19 11.0 0.4 0.3 10.3 0.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Pkinase PF00069.25 KDO19901.1 - 1.3e-51 175.5 0.0 1.8e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19901.1 - 3.1e-30 105.3 0.0 9.5e-30 103.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19901.1 - 9.7e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO19901.1 - 0.00011 21.2 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO19901.1 - 0.00079 19.4 0.0 0.19 11.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO19901.1 - 0.016 14.6 0.2 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.17 KDO19902.1 - 6e-09 36.4 0.0 1.2e-08 35.4 0.0 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 KDO19903.1 - 4.8e-14 52.8 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Integrin_b_cyt PF08725.11 KDO19903.1 - 0.03 14.0 21.5 0.82 9.4 0.3 7.2 3 1 6 9 9 9 0 Integrin beta cytoplasmic domain MIF4G_like PF09088.11 KDO19903.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 MIF4G like DLH PF01738.18 KDO19904.1 - 6.5e-05 22.6 0.0 7.7e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KDO19904.1 - 0.082 11.9 0.1 0.091 11.8 0.1 1.0 1 0 0 1 1 1 0 Chlorophyllase BK_channel_a PF03493.18 KDO19905.1 - 4.8e-23 81.2 0.0 1.3e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO19905.1 - 2.6e-11 43.3 11.7 1.5e-10 40.8 11.7 2.3 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KDO19905.1 - 6e-05 22.4 6.4 0.00012 21.4 6.4 1.5 1 0 0 1 1 1 1 Ion transport protein TrkA_C PF02080.21 KDO19905.1 - 0.00015 21.5 0.0 0.25 11.2 0.0 4.0 4 0 0 4 4 4 1 TrkA-C domain TrkA_N PF02254.18 KDO19905.1 - 0.0089 16.3 0.2 0.82 10.0 0.0 2.8 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.26 KDO19905.1 - 0.01 15.6 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel IRK PF01007.20 KDO19905.1 - 0.024 14.5 0.2 0.024 14.5 0.2 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain GGDEF_2 PF17853.1 KDO19905.1 - 0.18 12.0 1.7 0.34 11.2 0.1 2.3 3 0 0 3 3 3 0 GGDEF-like domain DUF2811 PF10929.8 KDO19905.1 - 0.42 10.9 1.6 2.8 8.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2811) SET PF00856.28 KDO19906.1 - 2.3e-23 83.4 0.8 2.7e-09 37.6 0.1 3.9 2 2 1 3 3 3 2 SET domain SAF PF08666.12 KDO19906.1 - 0.0037 17.9 0.0 11 6.7 0.0 3.5 4 0 0 4 4 4 2 SAF domain CHAT PF12770.7 KDO19908.1 - 1.1e-13 51.3 0.5 1.8e-13 50.5 0.0 1.6 2 0 0 2 2 2 1 CHAT domain AAA_16 PF13191.6 KDO19908.1 - 0.00032 21.1 0.1 0.0014 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KDO19908.1 - 0.0023 17.7 0.1 0.0059 16.4 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 KDO19908.1 - 0.021 15.3 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KDO19908.1 - 0.037 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KDO19908.1 - 0.047 14.0 0.4 0.4 10.9 0.4 2.4 1 1 0 1 1 1 0 AAA domain SQHop_cyclase_N PF13249.6 KDO19908.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain AAA_30 PF13604.6 KDO19908.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO19908.1 - 0.17 11.8 0.9 1.1 9.1 0.6 2.5 2 1 0 2 2 2 0 NACHT domain GLE1 PF07817.13 KDO19909.1 - 5.7e-11 42.1 0.0 9.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Guanylate_cyc PF00211.20 KDO19910.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain COG2 PF06148.11 KDO19911.1 - 0.0039 17.3 2.1 0.0039 17.3 2.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 HSBP1 PF06825.12 KDO19911.1 - 0.037 13.9 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 YscO-like PF16789.5 KDO19911.1 - 0.17 11.9 17.4 0.12 12.4 13.7 2.1 1 1 1 2 2 2 0 YscO-like protein DUF1664 PF07889.12 KDO19911.1 - 0.2 11.7 10.4 0.098 12.7 1.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KDO19911.1 - 0.51 9.6 13.4 0.73 9.1 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KxDL PF10241.9 KDO19911.1 - 0.58 10.5 15.8 9.6 6.6 0.2 3.7 2 1 2 4 4 4 0 Uncharacterized conserved protein PIP5K PF01504.18 KDO19911.1 - 0.71 9.0 4.4 0.27 10.4 1.1 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF948 PF06103.11 KDO19911.1 - 1.1 9.5 5.8 5.5 7.3 1.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KDO19911.1 - 1.5 8.9 6.3 1.6 8.8 2.9 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 KDO19911.1 - 1.6 9.1 20.8 5.9 7.3 1.4 2.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 KDO19911.1 - 1.8 8.8 9.7 0.54 10.5 4.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KDO19911.1 - 2.1 8.4 29.7 1.8 8.6 5.1 3.1 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 KDO19911.1 - 3.6 7.8 10.9 1.9 8.7 0.2 3.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 KDO19911.1 - 5.7 7.2 23.1 10 6.3 15.2 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 URO-D PF01208.17 KDO19912.1 - 5.8e-89 298.6 0.1 7.3e-89 298.3 0.1 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) BamHI PF02923.15 KDO19913.1 - 0.042 13.6 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease BamHI LRR_8 PF13855.6 KDO19914.1 - 0.00074 19.2 0.1 0.00074 19.2 0.1 2.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 KDO19914.1 - 0.001 19.4 2.2 0.0057 17.0 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KDO19914.1 - 0.0057 16.6 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DUF4035 PF13227.6 KDO19914.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Pkinase PF00069.25 KDO19915.1 - 1.6e-71 240.7 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19915.1 - 3e-36 125.0 0.0 3.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO19915.1 - 1.4e-06 27.9 0.0 4e-06 26.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KDO19915.1 - 0.00035 20.0 1.2 0.00056 19.3 0.3 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KDO19915.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 KDO19915.1 - 0.017 15.1 0.1 0.045 13.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KDO19915.1 - 0.09 12.4 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KDO19915.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_11 PF13414.6 KDO19916.1 - 1.1e-18 66.6 6.3 1.6e-10 40.5 0.7 4.1 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 KDO19916.1 - 8.8e-16 56.7 7.4 5.4e-08 32.4 0.4 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO19916.1 - 2.6e-15 55.5 11.4 1.8e-07 30.7 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO19916.1 - 1.4e-14 53.3 8.6 0.00078 19.7 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO19916.1 - 3e-10 40.1 7.8 7.1e-05 23.3 1.2 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO19916.1 - 6e-08 33.1 5.7 0.0002 21.8 0.6 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO19916.1 - 1.2e-07 31.9 11.8 0.00036 20.7 0.7 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO19916.1 - 1e-06 28.5 2.0 0.0016 18.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO19916.1 - 5.5e-06 26.9 13.3 0.00021 21.9 5.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KDO19916.1 - 1.9e-05 24.5 0.4 3.1e-05 23.8 0.4 1.3 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.6 KDO19916.1 - 0.0022 17.9 0.1 0.0022 17.9 0.1 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO19916.1 - 0.0046 16.8 8.2 0.029 14.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KDO19916.1 - 0.0098 16.3 3.3 0.8 10.1 0.3 2.3 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_4 PF07721.14 KDO19916.1 - 0.021 15.4 10.4 0.46 11.2 3.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KDO19916.1 - 0.039 14.3 4.0 0.35 11.2 0.3 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 KDO19916.1 - 0.17 10.8 0.4 0.24 10.3 0.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Proteasome PF00227.26 KDO19917.1 - 6.1e-57 192.2 0.0 7.3e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO19917.1 - 1.5e-12 46.9 0.0 2.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Caudo_TAP PF02413.17 KDO19918.1 - 0.043 14.0 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK OTU PF02338.19 KDO19919.1 - 2.7e-15 57.0 0.0 6.9e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease UIM PF02809.20 KDO19919.1 - 0.0092 15.8 21.9 0.75 9.9 2.5 5.2 4 0 0 4 4 4 2 Ubiquitin interaction motif Peptidase_C65 PF10275.9 KDO19919.1 - 0.047 13.1 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase C65 Otubain QueF_N PF14819.6 KDO19919.1 - 0.11 12.9 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term HEAT_2 PF13646.6 KDO19921.1 - 1.2e-11 44.8 1.6 2.9e-07 30.8 0.2 3.6 3 2 0 3 3 3 2 HEAT repeats WD40 PF00400.32 KDO19921.1 - 1.9e-11 44.3 1.6 0.28 12.1 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 KDO19921.1 - 5.9e-11 41.6 6.8 0.17 12.2 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KDO19921.1 - 6.8e-09 36.0 1.3 0.001 19.5 0.2 4.1 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 KDO19921.1 - 6.1e-07 29.6 0.0 0.066 13.2 0.0 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 KDO19921.1 - 7.5e-06 26.2 0.0 1 9.7 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4042 PF13251.6 KDO19921.1 - 0.0028 17.4 0.1 0.027 14.2 0.0 2.6 2 1 2 4 4 4 1 Domain of unknown function (DUF4042) PQQ_3 PF13570.6 KDO19921.1 - 0.082 13.4 1.8 0.58 10.7 0.9 2.8 2 1 0 2 2 2 0 PQQ-like domain Adaptin_N PF01602.20 KDO19921.1 - 0.13 10.8 0.3 0.73 8.3 0.1 1.9 2 1 1 3 3 3 0 Adaptin N terminal region Ank_4 PF13637.6 KDO19922.1 - 5.1e-13 49.3 1.7 3.9e-05 24.1 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO19922.1 - 6.3e-11 42.2 0.8 2.8e-05 24.4 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO19922.1 - 4.4e-10 39.6 1.0 1.4e-09 38.1 0.5 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19922.1 - 2.9e-09 37.4 0.3 8.5e-09 35.9 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19922.1 - 3.4e-08 33.1 0.9 0.00043 20.5 0.2 2.8 3 0 0 3 3 3 2 Ankyrin repeat FA_desaturase PF00487.24 KDO19923.1 - 7.8e-08 32.5 24.4 5.2e-05 23.2 18.1 2.4 1 1 1 2 2 2 2 Fatty acid desaturase Lon_C PF05362.13 KDO19924.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain Ribosomal_S8 PF00410.19 KDO19925.1 - 6.8e-22 77.8 0.1 1.2e-21 77.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 NOB1_Zn_bind PF08772.11 KDO19926.1 - 0.042 14.0 0.1 0.085 13.0 0.1 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Penaeidin PF05927.11 KDO19926.1 - 0.093 13.5 1.9 0.27 12.0 0.4 2.2 2 0 0 2 2 2 0 Penaeidin Diphthami_syn_2 PF01902.17 KDO19927.1 - 1.4e-44 152.2 0.0 2.3e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KDO19927.1 - 5.6e-27 94.2 0.8 6.2e-12 45.6 0.0 3.3 2 1 0 2 2 2 2 Endoribonuclease L-PSP DUF2102 PF09875.9 KDO19929.1 - 10 5.9 10.1 5.4 6.8 2.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) FeS PF04060.13 KDO19930.1 - 4.7 7.0 8.0 24 4.7 0.0 3.8 4 0 0 4 4 4 0 Putative Fe-S cluster Fip1 PF05182.13 KDO19931.1 - 8.9e-25 85.9 1.1 1.9e-24 84.9 1.1 1.6 1 0 0 1 1 1 1 Fip1 motif Pap_E4 PF02711.14 KDO19931.1 - 1.7 9.7 8.2 0.63 11.0 4.9 2.0 2 0 0 2 2 2 0 E4 protein Ribosomal_L21e PF01157.18 KDO19932.1 - 1.3e-45 153.3 8.7 2.2e-45 152.6 8.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Glucan_synthase PF02364.15 KDO19933.1 - 2.9e-187 624.5 17.5 8e-168 560.2 4.3 2.8 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO19933.1 - 3.7e-15 56.4 0.1 2.3e-13 50.6 0.1 3.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 PIN_6 PF17146.4 KDO19933.1 - 0.084 13.4 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 PIN domain of ribonuclease Fig1 PF12351.8 KDO19933.1 - 0.15 12.0 4.6 0.4 10.6 4.6 1.7 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 zf-met PF12874.7 KDO19935.1 - 0.00075 19.8 1.5 0.0013 19.0 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KDO19935.1 - 0.009 16.3 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KDO19935.1 - 0.032 14.5 2.1 0.057 13.7 2.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Mucin PF01456.17 KDO19935.1 - 1.7 8.6 8.8 0.21 11.6 4.5 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Peripla_BP_2 PF01497.18 KDO19936.1 - 1.4e-09 37.9 0.0 2.8e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein T4_Rnl2_C PF18043.1 KDO19937.1 - 0.0067 16.5 0.0 0.0076 16.4 0.0 1.1 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal DUF4203 PF13886.6 KDO19938.1 - 0.56 9.8 28.9 79 2.8 28.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4203 PF13886.6 KDO19939.1 - 3.8e-08 33.3 28.1 4.6e-08 33.0 28.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3039 PF11238.8 KDO19940.1 - 0.075 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) DUF4203 PF13886.6 KDO19940.1 - 0.26 10.9 30.1 0.11 12.2 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) PIP5K PF01504.18 KDO19941.1 - 1.9e-63 214.2 0.0 2.9e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DLIC PF05783.11 KDO19941.1 - 0.18 10.6 0.1 0.28 9.9 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ParD_like PF11903.8 KDO19941.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.4 3 0 0 3 3 3 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system SelK_SelG PF10961.8 KDO19944.1 - 0.16 12.6 0.1 0.42 11.3 0.1 1.6 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Pkinase PF00069.25 KDO19946.1 - 0.00082 18.8 0.0 0.00086 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19946.1 - 0.00097 18.5 0.0 0.0011 18.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4345 PF14248.6 KDO19948.1 - 8.4 6.3 15.0 1.4 8.8 10.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) HTH_37 PF13744.6 KDO19949.1 - 0.16 11.9 0.1 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Abhydrolase_6 PF12697.7 KDO19951.1 - 0.0061 17.2 3.7 0.0061 17.2 3.7 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KDO19951.1 - 0.028 14.1 0.2 0.11 12.1 0.2 1.9 1 1 0 1 1 1 0 PGAP1-like protein Ank_2 PF12796.7 KDO19953.1 - 1.6e-72 240.1 14.9 4.2e-15 56.1 0.0 6.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19953.1 - 3.2e-50 162.2 5.3 0.0011 19.3 0.0 14.4 14 0 0 14 14 14 12 Ankyrin repeat Ank PF00023.30 KDO19953.1 - 8.8e-49 161.9 34.0 1.3e-05 25.4 0.1 13.6 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.6 KDO19953.1 - 1.6e-45 152.9 10.9 1.2e-07 32.1 0.1 9.5 3 1 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19953.1 - 7e-40 134.6 23.0 2e-06 28.0 1.1 10.9 2 2 9 12 12 12 11 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO19953.1 - 9.7e-38 129.9 0.0 2.8e-37 128.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19953.1 - 1.4e-35 123.0 0.0 2.6e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO19953.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO19953.1 - 0.0043 17.0 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO19953.1 - 0.0044 16.4 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO19953.1 - 0.0095 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Fer4_13 PF13370.6 KDO19953.1 - 0.12 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I DUF4398 PF14346.6 KDO19953.1 - 0.88 10.2 12.6 1.1 10.0 3.4 4.7 4 2 2 6 6 6 0 Domain of unknown function (DUF4398) Ank_2 PF12796.7 KDO19954.1 - 3e-35 120.6 12.8 1.1e-12 48.3 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19954.1 - 9.5e-26 87.0 9.5 0.024 15.1 0.0 7.8 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KDO19954.1 - 3.7e-22 77.7 30.1 0.0014 19.0 0.1 7.5 7 1 1 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 KDO19954.1 - 5.7e-21 74.6 8.1 9e-08 32.5 0.0 5.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19954.1 - 8.8e-14 51.4 16.8 0.00051 20.3 0.1 6.3 3 2 5 8 8 8 5 Ankyrin repeats (many copies) PGM_PMM_III PF02880.16 KDO19954.1 - 0.013 15.7 0.8 0.031 14.5 0.7 1.6 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Init_tRNA_PT PF04179.12 KDO19954.1 - 0.1 12.9 0.7 2.2 8.6 0.1 2.6 1 1 0 2 2 2 0 Rit1 DUSP-like domain DUF4398 PF14346.6 KDO19954.1 - 0.78 10.4 11.3 2.2 8.9 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) ABC_membrane PF00664.23 KDO19955.1 - 1.8e-44 152.4 17.1 6e-24 85.1 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO19955.1 - 7.8e-36 123.6 0.0 7.7e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KDO19955.1 - 9.4e-08 31.7 0.2 0.033 13.9 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO19955.1 - 1.8e-07 31.2 0.0 0.00048 20.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO19955.1 - 2.4e-07 31.3 0.0 0.016 15.6 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO19955.1 - 1.2e-05 25.3 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 KDO19955.1 - 0.00027 20.1 0.0 0.32 10.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 KDO19955.1 - 0.00061 19.9 2.1 0.13 12.3 0.0 2.7 3 0 0 3 3 2 1 Dynamin family AAA_25 PF13481.6 KDO19955.1 - 0.00064 19.4 0.5 1.7 8.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KDO19955.1 - 0.0016 18.2 0.1 0.2 11.4 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein SMC_N PF02463.19 KDO19955.1 - 0.0017 17.9 0.3 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KDO19955.1 - 0.0021 17.5 0.1 0.68 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KDO19955.1 - 0.0055 17.0 0.1 4.4 7.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KDO19955.1 - 0.0072 16.4 0.0 0.1 12.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KDO19955.1 - 0.013 15.7 0.0 9.2 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO19955.1 - 0.014 14.6 0.1 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KDO19955.1 - 0.016 15.3 0.1 0.77 9.8 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 KDO19955.1 - 0.017 15.0 0.1 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KDO19955.1 - 0.023 14.8 0.0 0.93 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO19955.1 - 0.031 14.7 0.1 7.3 7.0 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_15 PF13175.6 KDO19955.1 - 0.034 13.9 0.0 7.1 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KDO19955.1 - 0.047 14.1 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KDO19955.1 - 0.058 13.1 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO19955.1 - 0.058 13.9 0.0 2.4 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO19955.1 - 0.06 13.9 0.2 20 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KDO19955.1 - 0.067 13.4 0.1 10 6.3 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 KDO19955.1 - 0.072 12.7 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KDO19955.1 - 0.074 12.9 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 KDO19955.1 - 0.15 12.0 0.0 0.8 9.6 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KDO19955.1 - 0.15 11.5 0.2 9.9 5.6 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region CLP1_P PF16575.5 KDO19955.1 - 0.25 11.1 0.2 1 9.2 0.1 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Ank_5 PF13857.6 KDO19956.1 - 5e-08 33.1 0.4 5e-06 26.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19956.1 - 5.9e-07 30.0 0.1 8.1e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19956.1 - 7.4e-07 29.0 0.2 0.02 15.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KDO19956.1 - 3.2e-05 24.2 0.9 0.0011 19.3 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KDO19956.1 - 0.00067 20.2 0.0 0.0013 19.3 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Disintegrin PF00200.23 KDO19957.1 - 3.5e-13 50.1 49.5 3e-05 24.7 3.3 4.8 3 2 1 4 4 4 4 Disintegrin LRR_6 PF13516.6 KDO19958.1 - 1.8e-25 86.8 12.9 0.0078 16.2 0.1 11.5 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 KDO19958.1 - 1.8e-12 47.3 0.4 0.028 14.9 0.1 6.1 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19958.1 - 2.2e-07 30.5 8.7 0.49 10.2 0.0 6.3 4 3 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 KDO19958.1 - 5.9e-07 29.2 0.0 13 6.8 0.0 6.9 7 0 0 7 7 7 1 Leucine Rich Repeat Ank_4 PF13637.6 KDO19960.1 - 5.6e-22 77.8 0.1 8.2e-08 32.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19960.1 - 3.9e-20 71.6 1.3 1.7e-09 37.8 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO19960.1 - 1.9e-18 66.8 0.1 1e-10 42.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO19960.1 - 6.1e-17 60.0 0.0 2.9e-06 27.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KDO19960.1 - 1.2e-14 53.9 1.1 0.00035 20.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat ALF PF03752.13 KDO19960.1 - 0.068 13.2 4.4 3.9 7.5 0.0 3.2 4 0 0 4 4 4 0 Short repeats of unknown function Myotub-related PF06602.14 KDO19961.1 - 2.5e-137 457.5 0.0 3.8e-137 457.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 KDO19961.1 - 4.5e-19 68.4 10.4 1e-18 67.2 10.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase PF00102.27 KDO19961.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KDO19961.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO19961.1 - 0.0042 17.1 0.1 0.0076 16.2 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.20 KDO19961.1 - 0.0056 16.6 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 GRAM domain 3-PAP PF12578.8 KDO19961.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein NAD_binding_6 PF08030.12 KDO19964.1 - 9.4e-11 42.1 0.0 9.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Elicitin PF00964.17 KDO19966.1 - 5.2e-07 29.7 0.4 8.3e-07 29.0 0.4 1.4 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO19967.1 - 4e-07 30.0 0.9 4e-07 30.0 0.9 1.7 2 0 0 2 2 2 1 Elicitin Diphtheria_C PF02763.14 KDO19969.1 - 0.023 14.4 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain GH114_assoc PF14741.6 KDO19969.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Aldo_ket_red PF00248.21 KDO19970.1 - 1.7e-41 142.4 0.0 1.7e-40 139.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.21 KDO19971.1 - 0.22 11.7 9.7 0.047 13.8 4.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF4606 PF15379.6 KDO19971.1 - 4.9 7.4 7.1 12 6.2 0.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) DnaJ PF00226.31 KDO19972.1 - 1.5e-21 76.2 1.9 1.5e-21 76.2 1.9 1.6 2 0 0 2 2 2 1 DnaJ domain Pox_A_type_inc PF04508.12 KDO19973.1 - 0.0046 16.7 1.2 3.9 7.5 0.0 3.1 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat GAS PF13851.6 KDO19973.1 - 0.0069 15.8 4.9 0.0069 15.8 4.9 3.7 3 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 KDO19973.1 - 0.15 10.9 5.9 4.1 6.2 0.1 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein Sec16 PF12932.7 KDO19973.1 - 0.49 11.0 3.8 32 5.2 0.0 2.7 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region EMP24_GP25L PF01105.24 KDO19973.1 - 0.58 10.1 9.7 0.79 9.6 7.1 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF724 PF05266.14 KDO19973.1 - 2.2 8.1 15.9 0.39 10.5 3.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KDO19973.1 - 3.4 7.7 25.1 2.9 8.0 5.3 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KDO19973.1 - 3.7 6.1 18.1 0.17 10.5 3.0 3.0 3 0 0 3 3 3 0 AAA domain FlxA PF14282.6 KDO19973.1 - 6.9 6.7 20.1 0.089 12.8 2.8 3.9 3 2 1 4 4 4 0 FlxA-like protein Cep57_CLD_2 PF14197.6 KDO19973.1 - 7.9 6.6 27.3 0.68 10.1 6.1 4.6 4 2 0 4 4 4 0 Centrosome localisation domain of PPC89 GpcrRhopsn4 PF10192.9 KDO19974.1 - 5.6e-45 153.8 12.9 5.6e-45 153.8 12.9 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KDO19974.1 - 0.0026 17.1 12.9 0.0043 16.4 12.9 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor Nucleos_tra2_N PF01773.20 KDO19974.1 - 6.2 7.5 12.0 4.6 7.9 0.6 3.8 4 0 0 4 4 4 0 Na+ dependent nucleoside transporter N-terminus Holin_SPP1 PF04688.13 KDO19974.1 - 8.3 6.7 6.1 3.3 8.0 2.6 2.2 2 0 0 2 2 2 0 SPP1 phage holin YrhK PF14145.6 KDO19976.1 - 5.2e-20 71.1 22.7 6e-08 32.4 3.9 3.5 3 0 0 3 3 3 3 YrhK-like protein DUF308 PF03729.13 KDO19976.1 - 6.7 7.1 17.0 2.2 8.7 1.5 3.4 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Pkinase PF00069.25 KDO19977.1 - 1.3e-48 165.7 0.0 1.9e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO19977.1 - 4e-47 160.7 0.0 5.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO19977.1 - 4.1e-09 36.6 9.9 0.00034 20.9 0.4 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO19977.1 - 0.00039 20.0 1.2 0.00084 18.9 1.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat Pkinase_fungal PF17667.1 KDO19977.1 - 0.0037 16.1 0.0 0.0054 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 KDO19977.1 - 0.02 14.9 2.7 20 5.5 0.1 4.2 3 1 1 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KDO19977.1 - 0.044 14.3 4.5 27 5.8 0.1 4.9 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO19977.1 - 0.059 13.1 12.6 0.55 10.0 1.1 3.7 2 1 3 5 5 5 0 Leucine rich repeat T4SS_CagC PF16943.5 KDO19977.1 - 0.075 13.2 0.1 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system APH PF01636.23 KDO19977.1 - 0.094 12.6 0.1 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO19977.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CSRNP_N PF16019.5 KDO19978.1 - 7e-05 22.8 0.1 0.00014 21.9 0.1 1.4 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus DUF3516 PF12029.8 KDO19978.1 - 0.04 13.0 0.4 0.052 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) cNMP_binding PF00027.29 KDO19979.1 - 1.3e-45 153.4 0.5 1.9e-18 66.3 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain FERM_M PF00373.18 KDO19979.1 - 0.24 11.8 1.6 0.66 10.4 0.0 2.6 4 0 0 4 4 4 0 FERM central domain SURF1 PF02104.15 KDO19980.1 - 2.3e-31 109.4 0.1 2.8e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 SURF1 family HTH_Tnp_Tc5 PF03221.16 KDO19981.1 - 1.2e-10 41.3 0.3 2.5e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HpaB_N PF11794.8 KDO19981.1 - 0.055 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Phage_int_SAM_4 PF13495.6 KDO19982.1 - 0.018 15.5 0.1 0.047 14.2 0.1 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DnaJ PF00226.31 KDO19983.1 - 2.4e-06 27.6 0.3 2.4e-06 27.6 0.3 3.2 4 0 0 4 4 4 1 DnaJ domain MAT1 PF06391.13 KDO19983.1 - 0.00096 19.0 14.7 0.00096 19.0 14.7 1.6 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 Fe_hyd_lg_C PF02906.14 KDO19983.1 - 0.062 13.0 2.3 0.11 12.1 2.2 1.4 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain V_ATPase_I PF01496.19 KDO19983.1 - 8.1 4.2 8.8 10 3.9 8.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IQ PF00612.27 KDO19984.1 - 0.69 9.9 17.7 0.032 14.0 5.7 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Peptidase_S8 PF00082.22 KDO19986.1 - 3e-12 46.4 0.1 3.5e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 KDO19987.1 - 8.1e-34 117.2 5.1 1.3e-33 116.5 5.1 1.4 1 0 0 1 1 1 1 Subtilase family RVT_3 PF13456.6 KDO19987.1 - 0.0028 17.4 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like SLH PF00395.20 KDO19987.1 - 0.12 12.3 0.0 0.49 10.4 0.0 2.0 1 0 0 1 1 1 0 S-layer homology domain Ysc84 PF04366.12 KDO19988.1 - 1.9e-30 105.3 0.1 2.2e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator Lipase_GDSL_2 PF13472.6 KDO19989.1 - 2.4e-26 93.2 0.0 2.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO19989.1 - 1.1e-15 58.1 0.0 2e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF459 PF04311.13 KDO19989.1 - 0.0013 17.9 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF459) Lipase_GDSL_2 PF13472.6 KDO19990.1 - 3.4e-23 83.0 0.1 4e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO19990.1 - 3.3e-14 53.3 0.0 6.6e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Terminase_GpA PF05876.12 KDO19990.1 - 0.011 14.4 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Pkinase_Tyr PF07714.17 KDO19991.1 - 2.3e-31 109.0 0.0 4.3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO19991.1 - 5.3e-30 104.7 0.0 1.1e-29 103.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KDO19991.1 - 0.092 12.3 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-RING_9 PF13901.6 KDO19992.1 - 0.0026 17.8 3.8 0.0042 17.1 3.8 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KDO19992.1 - 0.012 15.8 3.2 0.024 14.8 3.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 KDO19992.1 - 0.028 14.3 3.3 0.028 14.3 3.3 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KDO19992.1 - 0.042 14.2 5.9 0.1 12.9 5.9 1.7 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 KDO19992.1 - 0.16 12.1 4.4 0.69 10.0 3.5 2.5 2 1 1 3 3 3 0 PHD-finger Prok-RING_1 PF14446.6 KDO19992.1 - 0.19 11.6 5.5 0.6 10.1 5.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 KDO19992.1 - 0.73 9.8 6.8 3.6 7.5 6.8 2.1 1 1 0 1 1 1 0 PHD-finger Adeno_IVa2 PF02456.15 KDO19993.1 - 0.17 10.7 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein SpoU_methylase PF00588.19 KDO19994.1 - 9.3e-27 93.9 0.1 1.2e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family PdxJ PF03740.13 KDO19994.1 - 0.019 14.1 0.1 0.5 9.4 0.0 2.0 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ FYVE PF01363.21 KDO19995.1 - 1.1e-14 54.3 8.5 2e-14 53.5 8.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger TBCC_N PF16752.5 KDO19995.1 - 0.00089 19.7 0.2 0.0018 18.7 0.2 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain FYVE_2 PF02318.16 KDO19995.1 - 0.03 14.5 4.9 0.2 11.9 5.5 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.6 KDO19995.1 - 1.9 8.9 12.2 6.1 7.3 12.4 1.8 1 1 0 1 1 1 0 Ring finger domain DUF2256 PF10013.9 KDO19995.1 - 4.8 7.4 8.3 1.7 8.8 3.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KDO19995.1 - 7 6.6 9.1 1.5 8.7 4.3 2.2 2 0 0 2 2 2 0 HIT zinc finger LRR_6 PF13516.6 KDO19996.1 - 3.5e-15 54.7 13.2 0.28 11.3 0.0 8.2 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 KDO19996.1 - 2.2e-05 24.4 4.3 3.3 8.6 0.2 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 KDO19996.1 - 0.0021 18.4 10.0 7.6 7.1 0.0 5.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO19996.1 - 0.0049 16.6 11.1 43 4.0 3.9 5.6 3 1 1 4 4 4 1 Leucine rich repeat Ank_2 PF12796.7 KDO19999.1 - 8.8e-32 109.6 0.3 7.6e-10 39.3 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO19999.1 - 3.8e-21 75.2 2.7 8.3e-07 29.4 0.1 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO19999.1 - 7.2e-20 70.8 1.5 1.7e-06 28.2 0.1 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) WW PF00397.26 KDO19999.1 - 9.6e-16 57.6 5.5 3.6e-07 30.1 0.3 2.8 2 0 0 2 2 2 2 WW domain Ank_3 PF13606.6 KDO19999.1 - 6.5e-15 53.8 2.4 0.25 12.0 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KDO19999.1 - 7.3e-15 54.7 3.4 0.041 14.3 0.1 7.0 7 0 0 7 7 7 4 Ankyrin repeat Glyco_hyd_101C PF17451.2 KDO19999.1 - 0.0027 18.0 5.1 0.16 12.3 0.1 3.0 3 0 0 3 3 3 2 Glycosyl hydrolase 101 beta sandwich domain Polysacc_deac_1 PF01522.21 KDO19999.1 - 0.039 13.8 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase SprA-related PF12118.8 KDO19999.1 - 0.12 11.5 8.6 0.22 10.6 8.6 1.3 1 0 0 1 1 1 0 SprA-related family TipAS PF07739.13 KDO19999.1 - 9.5 6.8 7.4 1.4e+02 3.0 0.0 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain CoA_binding_3 PF13727.6 KDO20000.1 - 0.027 14.5 3.0 0.028 14.4 1.5 1.7 1 1 0 1 1 1 0 CoA-binding domain PRA1 PF03208.19 KDO20000.1 - 1.3 8.7 9.1 1.3 8.6 1.1 2.0 1 1 1 2 2 2 0 PRA1 family protein FtsL PF04999.13 KDO20000.1 - 2.5 8.1 5.3 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Cell division protein FtsL AIF_C PF14721.6 KDO20001.1 - 3.6e-19 69.4 0.0 1.7e-08 34.9 0.0 2.3 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 KDO20001.1 - 2.5e-17 63.0 0.0 3.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO20001.1 - 2.8e-07 31.0 0.0 5.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Acylphosphatase PF00708.18 KDO20006.1 - 9.3e-12 45.2 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Methyltransf_15 PF09445.10 KDO20007.1 - 1.3e-16 60.6 0.1 1.9e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 KDO20007.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Pkinase PF00069.25 KDO20008.1 - 2.7e-11 43.4 0.1 8.8e-09 35.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20008.1 - 3.6e-05 23.2 0.0 3.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO20008.1 - 0.084 12.2 0.0 0.084 12.2 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Trypsin_2 PF13365.6 KDO20010.1 - 0.00014 22.8 0.1 0.00017 22.5 0.1 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DDE_Tnp_4 PF13359.6 KDO20011.1 - 1e-07 31.8 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1389 PF07146.11 KDO20012.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) Phage_GP20 PF06810.11 KDO20012.1 - 0.045 13.5 17.8 0.047 13.5 1.3 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 Atx10homo_assoc PF09759.9 KDO20012.1 - 1.2 9.2 6.2 2.6 8.1 0.6 2.5 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Trypsin_2 PF13365.6 KDO20013.1 - 6.2e-17 62.9 0.1 1.1e-16 62.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain CBM_1 PF00734.18 KDO20013.1 - 5.4e-11 42.3 4.1 1.9e-10 40.5 4.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO20013.1 - 3.3e-06 26.5 58.2 0.0002 20.8 22.3 3.7 3 1 1 4 4 4 3 PT repeat Trypsin PF00089.26 KDO20013.1 - 0.00053 19.9 4.9 0.0037 17.1 4.9 2.1 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KDO20013.1 - 0.031 12.9 0.8 2.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 SOG2 PF10428.9 KDO20013.1 - 3.6 6.7 5.8 5.1 6.2 5.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KDO20013.1 - 6.8 6.5 9.6 10 5.9 9.6 1.2 1 0 0 1 1 1 0 SPX domain RHS_repeat PF05593.14 KDO20014.1 - 0.093 13.3 0.2 0.19 12.3 0.2 1.5 1 0 0 1 1 1 0 RHS Repeat RCC1 PF00415.18 KDO20020.1 - 1.8e-73 243.0 11.3 2.2e-15 57.0 0.0 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO20020.1 - 3.5e-44 147.8 29.2 3.2e-09 36.3 0.0 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KDO20020.1 - 0.0019 18.7 2.2 27 5.2 0.0 5.1 4 2 1 6 6 6 1 SUKH-3 immunity protein DUF4213 PF13938.6 KDO20020.1 - 0.0033 17.6 0.9 2.8 8.2 0.0 3.2 3 1 0 3 3 3 2 Putative heavy-metal chelation Methyltranf_PUA PF13636.6 KDO20020.1 - 0.051 13.6 0.6 9 6.4 0.1 2.6 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF Thioredoxin_8 PF13905.6 KDO20021.1 - 1.9e-29 101.8 0.0 3.2e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO20021.1 - 1.9e-10 40.6 0.0 1.2e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 KDO20021.1 - 2.4e-05 24.1 0.0 4.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KDO20021.1 - 6.9e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KDO20021.1 - 0.00068 20.1 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain fn3 PF00041.21 KDO20021.1 - 0.0011 19.3 0.2 0.076 13.4 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Thioredoxin_9 PF14595.6 KDO20021.1 - 0.024 14.4 0.0 0.44 10.3 0.1 2.6 2 1 0 2 2 2 0 Thioredoxin CATSPERB PF15149.6 KDO20021.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family Elicitin PF00964.17 KDO20022.1 - 0.0014 18.7 2.0 0.0017 18.4 0.4 1.9 1 1 1 2 2 2 1 Elicitin Zip PF02535.22 KDO20023.1 - 9.7e-40 136.8 19.5 1.3e-38 133.0 19.5 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter PTR2 PF00854.21 KDO20024.1 - 0.00015 20.8 1.6 0.00015 20.8 1.6 1.9 2 0 0 2 2 2 1 POT family PTR2 PF00854.21 KDO20025.1 - 2.3e-06 26.7 0.2 4.3e-06 25.8 0.2 1.4 1 1 0 1 1 1 1 POT family zf-CCCH PF00642.24 KDO20027.1 - 4.3e-09 36.1 2.6 4.3e-09 36.1 2.6 2.4 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KDO20027.1 - 4e-06 26.6 6.1 7.3e-06 25.7 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO20027.1 - 7.4e-06 26.2 8.4 7.4e-06 26.2 8.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO20027.1 - 1.9e-05 24.6 7.9 4.2e-05 23.5 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KDO20027.1 - 3.1e-05 23.9 5.0 8.8e-05 22.4 5.0 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KDO20027.1 - 0.00027 20.7 10.0 0.00058 19.7 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO20027.1 - 0.00032 20.6 11.2 0.00064 19.6 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KDO20027.1 - 0.00055 19.7 9.1 0.0011 18.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 KDO20027.1 - 0.004 16.9 3.3 0.004 16.9 3.3 2.7 3 0 0 3 3 3 1 CCCH-type zinc finger zf-RING_10 PF16685.5 KDO20027.1 - 0.016 15.3 4.8 0.016 15.3 4.8 1.7 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KDO20027.1 - 0.033 14.3 7.8 0.091 12.9 7.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KDO20027.1 - 0.15 12.0 6.3 0.32 10.9 6.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.12 KDO20027.1 - 0.17 11.9 5.8 0.42 10.6 5.8 1.7 1 0 0 1 1 1 0 zinc-ribbons FYVE PF01363.21 KDO20027.1 - 0.27 11.4 8.9 0.89 9.7 8.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-CCCH_2 PF14608.6 KDO20027.1 - 9.2 6.9 9.6 0.75 10.4 4.2 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger HAUS-augmin3 PF14932.6 KDO20028.1 - 0.0039 16.8 13.5 0.0039 16.8 13.5 5.6 1 1 4 5 5 5 1 HAUS augmin-like complex subunit 3 Filament PF00038.21 KDO20028.1 - 0.25 10.9 71.7 0.13 11.8 10.5 4.2 1 1 3 4 4 4 0 Intermediate filament protein DUF4062 PF13271.6 KDO20028.1 - 5.9 7.3 6.9 5.7 7.4 0.3 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4062) TACC_C PF05010.14 KDO20029.1 - 3.7e-06 26.9 68.7 4.1e-06 26.7 24.7 4.0 1 1 2 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 KDO20029.1 - 8.8e-05 21.4 10.6 8.8e-05 21.4 10.6 4.0 1 1 2 4 4 4 2 AAA domain HALZ PF02183.18 KDO20029.1 - 0.0038 17.4 3.1 0.0038 17.4 3.1 9.3 9 0 0 9 9 9 1 Homeobox associated leucine zipper DUF148 PF02520.17 KDO20029.1 - 0.011 15.8 4.0 0.011 15.8 4.0 7.6 5 3 0 7 7 7 0 Domain of unknown function DUF148 CCDC144C PF14915.6 KDO20029.1 - 0.022 13.9 83.9 0.014 14.5 17.3 4.3 1 1 2 4 4 4 0 CCDC144C protein coiled-coil region TPR_MLP1_2 PF07926.12 KDO20029.1 - 0.061 13.4 105.6 0.2 11.7 13.6 7.4 2 2 5 7 7 7 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KDO20029.1 - 0.068 13.2 51.3 0.71 9.9 2.7 7.8 3 2 5 9 9 9 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KDO20029.1 - 0.11 11.4 90.9 0.027 13.4 9.0 5.4 1 1 4 6 6 6 0 Spc7 kinetochore protein Filament PF00038.21 KDO20029.1 - 0.26 10.9 80.6 0.038 13.6 8.5 5.4 1 1 4 5 5 5 0 Intermediate filament protein Golgin_A5 PF09787.9 KDO20029.1 - 0.28 10.6 84.0 0.011 15.3 8.0 5.5 1 1 4 5 5 5 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KDO20029.1 - 0.92 9.5 49.0 0.15 12.1 3.7 6.5 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 KDO20029.1 - 1.3 7.3 83.4 0.049 12.0 12.1 3.6 1 1 1 3 3 3 0 Mitotic checkpoint protein Fez1 PF06818.15 KDO20029.1 - 1.7 9.0 84.3 0.42 11.1 5.0 5.5 1 1 4 5 5 4 0 Fez1 MbeD_MobD PF04899.12 KDO20032.1 - 0.011 15.8 3.0 0.057 13.5 2.6 2.4 1 1 1 2 2 2 0 MbeD/MobD like CorA PF01544.18 KDO20032.1 - 8.2 5.7 6.6 2.7 7.2 2.2 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1359 PF07097.11 KDO20033.1 - 0.12 12.6 0.1 0.32 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) DUF4140 PF13600.6 KDO20033.1 - 0.13 12.7 2.6 0.19 12.2 0.1 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.18 KDO20033.1 - 0.19 11.0 3.5 5.1 6.3 0.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Methyltransf_25 PF13649.6 KDO20035.1 - 1.1e-08 35.6 0.1 1.9e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO20035.1 - 2.1e-06 27.6 0.0 2.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KDO20035.1 - 8.3e-06 25.8 0.1 1.2e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KDO20035.1 - 8.8e-06 25.3 0.1 1.2e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 KDO20035.1 - 7.2e-05 23.4 0.1 0.00016 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO20035.1 - 0.00013 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 KDO20035.1 - 0.00015 21.3 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 KDO20035.1 - 0.001 18.6 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KDO20035.1 - 0.002 18.0 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KDO20035.1 - 0.0056 16.3 0.1 0.0075 15.9 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 KDO20035.1 - 0.02 15.6 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KDO20035.1 - 0.038 13.5 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 KDO20035.1 - 0.063 12.9 0.2 0.82 9.3 0.2 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 KDO20035.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KDO20035.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 KDO20035.1 - 0.2 11.2 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Dpy-30 PF05186.13 KDO20037.1 - 1.9e-05 24.3 2.9 0.047 13.4 0.7 2.5 2 0 0 2 2 2 2 Dpy-30 motif HEAT_EZ PF13513.6 KDO20037.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 HEAT-like repeat RrnaAD PF00398.20 KDO20038.1 - 1.8e-07 30.5 0.0 2.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KDO20038.1 - 8.8e-05 23.1 0.0 0.00015 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO20038.1 - 0.0047 16.8 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KDO20038.1 - 0.0075 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KDO20038.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO20038.1 - 0.067 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LRR_9 PF14580.6 KDO20039.1 - 5.8e-18 65.0 0.2 1.4e-17 63.7 0.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat C2 PF00168.30 KDO20039.1 - 8.8e-15 54.9 0.1 4.5e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain LRR_4 PF12799.7 KDO20039.1 - 9.7e-12 44.9 8.7 2.6e-06 27.7 0.4 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO20039.1 - 1e-09 38.0 3.3 1e-09 38.0 3.3 4.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KDO20039.1 - 0.0049 17.2 5.6 0.48 11.2 0.1 5.0 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO20039.1 - 0.015 15.3 7.4 8 6.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat N-Term_TEN PF11474.8 KDO20039.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Ly49 PF08391.10 KDO20039.1 - 6.1 7.2 8.6 0.12 12.7 0.7 2.2 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region HECT PF00632.25 KDO20041.1 - 1.5e-55 188.9 0.0 2.4e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KDO20041.1 - 2.3e-21 76.1 0.0 4.4e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PCMT PF01135.19 KDO20041.1 - 8e-15 55.2 0.0 1.6e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KDO20041.1 - 0.003 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WWE PF02825.20 KDO20041.1 - 0.01 16.4 0.0 0.026 15.1 0.0 1.7 1 0 0 1 1 1 0 WWE domain REV1_C PF16727.5 KDO20041.1 - 4.1 7.9 4.9 1.2 9.6 0.2 2.6 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain DnaJ PF00226.31 KDO20042.1 - 1.8e-06 28.0 1.8 3e-06 27.2 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain GHL13 PF14883.6 KDO20042.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 7tm_2 PF00002.24 KDO20043.1 - 4e-18 65.6 16.5 2.8e-17 62.9 16.5 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KDO20043.1 - 3.2e-15 56.1 10.8 4.5e-15 55.6 10.8 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KDO20043.1 - 1.9e-06 27.8 8.7 2.5e-06 27.4 7.7 1.7 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 TMEM192 PF14802.6 KDO20043.1 - 0.94 8.5 2.9 0.81 8.7 0.7 1.9 2 0 0 2 2 2 0 TMEM192 family EamA PF00892.20 KDO20044.1 - 3.2e-09 37.1 34.2 0.00014 22.0 15.4 2.4 2 0 0 2 2 2 2 EamA-like transporter family FH2 PF02181.23 KDO20046.1 - 0.0073 15.5 0.8 0.0085 15.2 0.8 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Jnk-SapK_ap_N PF09744.9 KDO20046.1 - 0.0081 16.4 1.7 0.0091 16.2 1.7 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ANAPC_CDC26 PF10471.9 KDO20046.1 - 0.024 15.4 1.2 0.057 14.3 1.0 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 HTH_16 PF12645.7 KDO20046.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MbeD_MobD PF04899.12 KDO20046.1 - 0.033 14.3 2.6 0.053 13.6 2.5 1.5 1 1 0 1 1 1 0 MbeD/MobD like Tweety PF04906.13 KDO20046.1 - 0.044 12.4 1.5 0.05 12.3 1.5 1.1 1 0 0 1 1 1 0 Tweety DUF2968 PF11180.8 KDO20046.1 - 0.67 9.6 10.4 4.5 6.9 9.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Tmemb_9 PF05434.11 KDO20047.1 - 0.17 11.8 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 TMEM9 DUF4175 PF13779.6 KDO20047.1 - 0.23 9.3 0.3 0.25 9.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) IQ PF00612.27 KDO20048.1 - 0.0012 18.4 0.8 0.0012 18.4 0.8 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif ArnB_C PF18677.1 KDO20048.1 - 0.024 14.7 1.6 0.21 11.7 0.2 2.1 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain CAF-1_p150 PF11600.8 KDO20048.1 - 0.1 12.3 9.2 0.12 12.1 9.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WD40 PF00400.32 KDO20049.1 - 1e-17 64.1 10.2 0.0006 20.6 0.0 8.6 9 0 0 9 9 9 3 WD domain, G-beta repeat EF-hand_1 PF00036.32 KDO20049.1 - 2.4e-15 54.8 5.4 0.0092 15.5 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO20049.1 - 4.1e-15 56.0 5.2 1.5e-07 31.8 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO20049.1 - 8.3e-14 50.3 3.4 0.0093 15.8 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO20049.1 - 4.8e-09 35.3 6.1 0.11 12.0 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KDO20049.1 - 0.00041 20.1 3.3 0.31 10.9 0.2 4.0 3 1 1 4 4 4 2 EF-hand domain pair PQQ_3 PF13570.6 KDO20049.1 - 1.5 9.4 3.2 1.3 9.6 0.3 2.5 3 0 0 3 3 3 0 PQQ-like domain GlcNAc PF11397.8 KDO20050.1 - 1.6e-43 149.6 0.0 8.3e-37 127.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 KDO20050.1 - 0.014 15.2 0.0 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 EF-hand_1 PF00036.32 KDO20051.1 - 6.7e-11 40.9 2.4 0.0012 18.3 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KDO20051.1 - 9.3e-08 32.4 4.2 0.00018 21.9 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO20051.1 - 1.1e-07 31.2 4.0 0.073 13.0 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KDO20051.1 - 0.00011 21.5 3.2 0.045 13.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO20051.1 - 0.094 12.6 1.0 5.7 6.9 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair GlcNAc PF11397.8 KDO20052.1 - 3.5e-26 92.5 0.1 8e-19 68.3 0.0 2.5 1 1 2 3 3 3 2 Glycosyltransferase (GlcNAc) Pkinase_Tyr PF07714.17 KDO20053.1 - 6.1e-42 143.7 0.0 6.9e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20053.1 - 1.3e-40 139.5 0.0 1.7e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO20053.1 - 0.00035 20.6 1.2 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO20053.1 - 0.00082 18.3 0.1 0.0011 17.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO20053.1 - 0.0017 17.4 0.0 0.0023 16.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO20053.1 - 0.028 13.8 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20053.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Ank_2 PF12796.7 KDO20054.1 - 2.8e-61 204.1 19.2 6.6e-14 52.3 0.0 6.6 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20054.1 - 1.9e-46 155.5 21.4 1.6e-08 34.6 0.4 8.2 4 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20054.1 - 5.6e-46 154.4 5.0 5.2e-10 39.7 0.1 7.9 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20054.1 - 3.6e-43 140.6 11.9 9.8e-05 22.5 0.0 11.2 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 KDO20054.1 - 2.7e-39 131.9 31.2 7.2e-06 26.2 0.1 10.6 10 2 1 11 11 11 7 Ankyrin repeat FYVE PF01363.21 KDO20055.1 - 5.3e-24 84.1 35.6 1.3e-15 57.3 10.8 2.3 2 0 0 2 2 2 2 FYVE zinc finger DUF3018 PF11455.8 KDO20055.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Sensor PF13796.6 KDO20056.1 - 0.0026 17.8 4.2 0.0026 17.8 4.2 1.3 1 1 0 1 1 1 1 Putative sensor MgtC PF02308.16 KDO20056.1 - 0.037 14.4 3.9 0.041 14.3 3.4 1.3 1 1 0 1 1 1 0 MgtC family Ctr PF04145.15 KDO20056.1 - 2.2 8.9 10.7 0.82 10.3 4.7 2.0 1 1 1 2 2 2 0 Ctr copper transporter family Myb_DNA-binding PF00249.31 KDO20058.1 - 5.6e-08 32.8 0.1 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MRC1 PF09444.10 KDO20058.1 - 0.057 13.9 2.7 0.97 9.9 1.0 2.1 2 0 0 2 2 2 0 MRC1-like domain DNA_alkylation PF08713.11 KDO20059.1 - 0.057 13.1 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme RuvX PF03652.15 KDO20059.1 - 0.13 12.7 0.1 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Thioredoxin_8 PF13905.6 KDO20060.1 - 7.1e-19 67.9 0.4 5.9e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KDO20060.1 - 9.6e-09 35.1 0.4 6.3e-06 26.0 0.0 2.4 2 1 0 2 2 2 2 Redoxin Thioredoxin PF00085.20 KDO20060.1 - 1.5e-07 31.3 0.0 9.2e-06 25.6 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin AhpC-TSA PF00578.21 KDO20060.1 - 3.1e-05 23.9 0.1 0.00017 21.5 0.0 2.0 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KDO20060.1 - 0.0011 18.7 0.1 0.023 14.5 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO20060.1 - 0.0023 18.4 0.1 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain DUF953 PF06110.11 KDO20060.1 - 0.029 14.0 0.3 0.45 10.1 0.3 2.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) APOBEC4 PF18775.1 KDO20060.1 - 0.15 12.2 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 APOBEC4 Thioredoxin_8 PF13905.6 KDO20061.1 - 5.5e-17 61.9 0.0 1.6e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 KDO20061.1 - 8.6e-07 28.9 0.0 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 KDO20061.1 - 1.1e-06 28.4 0.0 0.00018 21.2 0.0 2.2 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KDO20061.1 - 0.00026 20.9 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KDO20061.1 - 0.0039 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KDO20061.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 KDO20061.1 - 0.026 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KDO20061.1 - 0.065 13.4 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Myb_DNA-binding PF00249.31 KDO20062.1 - 5e-08 33.0 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain MnmE_helical PF12631.7 KDO20062.1 - 0.059 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 MnmE helical domain Kinase-PPPase PF03618.14 KDO20062.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase/pyrophosphorylase PX PF00787.24 KDO20063.1 - 6.7e-07 29.3 0.1 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 PX domain Sel1 PF08238.12 KDO20064.1 - 1.6e-27 95.3 6.3 2.3e-07 31.3 0.0 6.5 7 0 0 7 7 7 4 Sel1 repeat TPR_2 PF07719.17 KDO20064.1 - 0.11 12.7 0.1 12 6.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 KDO20065.1 - 1.6e-41 140.2 0.4 1.7e-15 56.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4148 PF13663.6 KDO20065.1 - 0.11 12.7 0.4 0.24 11.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) LRR_4 PF12799.7 KDO20069.1 - 0.031 14.7 0.4 1.4 9.5 0.0 3.7 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO20069.1 - 0.033 14.0 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat DNase-RNase PF02577.14 KDO20069.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Bifunctional nuclease LRR_2 PF07723.13 KDO20072.1 - 0.65 10.8 5.3 16 6.4 0.4 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Pentapeptide_4 PF13599.6 KDO20073.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DJ-1_PfpI PF01965.24 KDO20075.1 - 2.2e-21 76.4 0.0 2.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family HA PF03457.14 KDO20076.1 - 3.1e-27 94.7 0.2 3.3e-06 27.3 0.0 7.4 7 1 0 7 7 7 6 Helicase associated domain LRR_4 PF12799.7 KDO20078.1 - 0.064 13.7 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Ank_4 PF13637.6 KDO20079.1 - 5.6e-08 33.2 0.1 4.4e-07 30.3 0.0 2.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20079.1 - 2.2e-07 31.3 0.1 1.6e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO20079.1 - 3.8e-05 24.0 0.6 0.13 12.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO20079.1 - 0.014 15.7 0.1 0.074 13.4 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20079.1 - 0.026 15.0 0.0 0.98 10.2 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Cwf_Cwc_15 PF04889.12 KDO20079.1 - 0.22 11.2 11.5 0.33 10.7 11.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 KDO20079.1 - 3.2 8.5 12.6 6.6 7.5 12.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_17 PF17120.5 KDO20080.1 - 1.1e-10 41.0 14.6 1.1e-10 41.0 14.6 2.4 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KDO20080.1 - 6.6e-05 23.1 7.5 6.6e-05 23.1 7.5 2.7 1 1 1 2 2 2 1 Zinc-ribbon like family WD40 PF00400.32 KDO20080.1 - 0.00019 22.1 0.0 0.00019 22.1 0.0 3.2 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 KDO20080.1 - 0.0036 17.6 3.7 0.0036 17.6 3.7 2.6 2 0 0 2 2 2 1 Ring finger domain DZR PF12773.7 KDO20080.1 - 0.4 10.8 10.2 1.7 8.8 10.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 KDO20080.1 - 4.4 7.2 11.8 0.29 11.0 3.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 KDO20080.1 - 4.4 5.0 4.2 5.9 4.6 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Lipase_3 PF01764.25 KDO20081.1 - 8.3e-07 29.0 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KDO20081.1 - 0.0097 15.5 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) MMR_HSR1 PF01926.23 KDO20081.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO20081.1 - 0.023 15.0 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 KDO20081.1 - 0.052 14.2 5.5 0.053 14.1 0.0 2.8 2 1 1 3 3 3 0 Alpha/beta hydrolase family VirE PF05272.11 KDO20081.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E TPR_9 PF13371.6 KDO20083.1 - 4.7e-07 29.9 0.2 4.7e-07 29.9 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20083.1 - 1.2e-05 24.9 0.0 0.0034 17.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20083.1 - 2.9e-05 23.9 0.0 0.019 15.0 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20083.1 - 0.0008 20.0 0.1 0.0008 20.0 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20083.1 - 0.087 13.2 0.0 0.62 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20083.1 - 0.66 11.0 0.0 0.66 11.0 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 KDO20084.1 - 6.9e-16 58.3 14.1 4.2e-05 24.2 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KDO20084.1 - 2.4e-10 39.9 14.5 2.4e-10 39.9 14.5 2.1 1 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KDO20084.1 - 0.00039 20.6 7.6 0.00039 20.6 7.6 2.5 1 1 1 2 2 2 1 Zinc-ribbon like family zf-RING_2 PF13639.6 KDO20084.1 - 0.01 16.1 3.3 0.01 16.1 3.3 2.6 2 0 0 2 2 2 0 Ring finger domain Phage_min_tail PF05939.13 KDO20084.1 - 0.013 15.8 0.1 0.037 14.4 0.1 1.7 1 0 0 1 1 1 0 Phage minor tail protein DZR PF12773.7 KDO20084.1 - 0.95 9.5 9.7 3.5 7.7 9.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon DEK_C PF08766.11 KDO20086.1 - 2.6e-05 24.0 2.8 2.6e-05 24.0 2.8 1.4 2 0 0 2 2 2 1 DEK C terminal domain TubC_N PF18563.1 KDO20086.1 - 0.069 13.1 0.1 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 TubC N-terminal docking domain LAT PF15234.6 KDO20087.1 - 0.0095 15.7 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Linker for activation of T-cells AJAP1_PANP_C PF15298.6 KDO20087.1 - 0.12 12.6 2.4 0.16 12.2 2.4 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus EF-hand_7 PF13499.6 KDO20088.1 - 9.8e-09 35.6 0.3 2.2e-08 34.4 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO20088.1 - 2.6e-07 29.7 5.7 0.00082 18.8 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO20088.1 - 3.4e-06 26.5 0.6 0.012 15.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO20088.1 - 7.3e-06 25.2 1.8 0.0049 16.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO20088.1 - 0.0073 16.1 3.5 0.013 15.3 1.5 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 KDO20088.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain HutP PF09021.11 KDO20089.1 - 0.069 13.5 1.0 0.18 12.1 1.0 1.7 1 0 0 1 1 1 0 HutP Fib_alpha PF08702.10 KDO20089.1 - 0.22 11.7 11.0 3.3 7.9 0.9 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 KDO20089.1 - 0.27 11.1 1.7 5.6 6.9 0.2 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Med9 PF07544.13 KDO20089.1 - 9.8 6.3 11.8 5.9 7.0 1.0 3.8 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Ribonuc_2-5A PF06479.12 KDO20090.1 - 0.031 14.5 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease 2-5A Peptidase_M48 PF01435.18 KDO20091.1 - 9.5e-12 45.1 0.4 2.4e-11 43.8 0.4 1.7 1 1 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.6 KDO20091.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Glyco_transf_20 PF00982.21 KDO20092.1 - 5.9e-96 322.0 0.0 2.4e-95 320.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KDO20092.1 - 2.4e-37 128.3 0.0 6.7e-37 126.8 0.0 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 KDO20092.1 - 2.8e-08 33.6 0.0 5.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Hydrolase_3 PF08282.12 KDO20092.1 - 0.016 15.0 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.14 KDO20093.1 - 3.5e-21 75.4 0.5 3.5e-21 75.4 0.5 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KDO20093.1 - 8e-17 61.3 0.9 1.5e-08 34.7 0.4 3.9 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KDO20093.1 - 0.019 15.1 0.0 1.2 9.2 0.0 3.1 4 0 0 4 4 4 0 Multicopper oxidase Cu-oxidase_2 PF07731.14 KDO20094.1 - 2e-21 76.2 0.6 2e-21 76.2 0.6 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KDO20094.1 - 4e-12 46.2 0.3 3.2e-09 36.8 0.4 3.2 2 1 0 2 2 2 1 Multicopper oxidase UPF0176_N PF17773.1 KDO20095.1 - 9.2e-13 48.4 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KDO20095.1 - 9.1e-09 35.8 0.0 1.4e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zinc_ribbon_9 PF14369.6 KDO20095.1 - 0.0038 17.4 0.3 0.024 14.9 0.5 2.1 1 1 1 2 2 2 1 zinc-ribbon Rhodanese_C PF12368.8 KDO20095.1 - 0.0056 17.0 0.4 0.011 16.1 0.4 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal DUF2430 PF10353.9 KDO20095.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) Myotub-related PF06602.14 KDO20096.1 - 5.2e-128 426.9 0.0 7.1e-128 426.4 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KDO20096.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO20096.1 - 0.027 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO20096.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase 3-PAP PF12578.8 KDO20096.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.7 4 0 0 4 4 4 0 Myotubularin-associated protein Cation_ATPase_C PF00689.21 KDO20097.1 - 2.8e-06 27.2 0.2 2.8e-06 27.2 0.2 2.6 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO20097.1 - 0.0019 17.8 0.0 0.0019 17.8 0.0 2.4 4 0 0 4 4 4 1 E1-E2 ATPase Not3 PF04065.15 KDO20098.1 - 0.037 13.4 0.1 0.088 12.2 0.1 1.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component bZIP_1 PF00170.21 KDO20099.1 - 0.093 12.8 2.0 0.17 12.0 2.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor CENP-F_N PF10481.9 KDO20100.1 - 0.0086 15.7 1.4 0.015 15.0 1.4 1.4 1 0 0 1 1 1 1 Cenp-F N-terminal domain FYVE PF01363.21 KDO20100.1 - 0.019 15.1 15.0 0.055 13.6 15.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger Phage_GP20 PF06810.11 KDO20100.1 - 0.21 11.4 3.5 0.51 10.1 2.6 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 C1_2 PF03107.16 KDO20100.1 - 0.4 11.0 9.5 0.11 12.8 6.0 1.9 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 KDO20100.1 - 0.57 10.3 7.2 3 8.0 6.8 2.1 1 1 1 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.16 KDO20100.1 - 0.67 10.2 6.0 2.1 8.6 6.0 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger SlyX PF04102.12 KDO20100.1 - 3.5 8.3 5.4 0.6 10.8 1.1 2.0 2 0 0 2 2 2 0 SlyX zf-RING_2 PF13639.6 KDO20100.1 - 5.2 7.5 8.8 34 4.9 5.2 2.7 2 0 0 2 2 2 0 Ring finger domain FAA_hydrolase PF01557.18 KDO20101.1 - 4.9e-68 229.1 0.0 6.2e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 KDO20101.1 - 0.067 14.1 0.1 0.15 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) DUF4381 PF14316.6 KDO20106.1 - 0.34 11.2 9.9 0.95 9.7 0.5 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Ribosomal_L7Ae PF01248.26 KDO20107.1 - 9.7e-11 41.3 0.2 1.9e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 KDO20107.1 - 2.7e-06 27.1 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.26 KDO20107.1 - 0.036 14.5 0.0 7.9 7.0 0.0 2.9 2 0 0 2 2 2 0 Heavy-metal-associated domain DSS1_SEM1 PF05160.13 KDO20107.1 - 0.28 11.3 3.7 6.7 6.9 0.3 2.4 2 0 0 2 2 2 0 DSS1/SEM1 family NAM-associated PF14303.6 KDO20107.1 - 6.4 7.5 9.7 3.5 8.3 7.5 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain NAD_binding_8 PF13450.6 KDO20108.1 - 2.1e-12 47.1 0.1 1.1e-11 44.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KDO20108.1 - 1.3e-10 41.1 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KDO20108.1 - 5.5e-09 36.1 0.2 4.6e-08 33.0 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 KDO20108.1 - 9.8e-05 21.6 0.1 0.00014 21.1 0.1 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase FAD_binding_2 PF00890.24 KDO20108.1 - 0.0012 18.0 0.8 0.0051 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KDO20108.1 - 0.002 17.4 0.0 0.041 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO20108.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KDO20108.1 - 0.047 14.2 0.2 0.15 12.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C1 PF00112.23 KDO20109.1 - 9.5e-58 195.8 14.1 9.5e-58 195.8 14.1 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20109.1 - 0.00054 18.9 2.4 0.075 11.8 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family FAM193_C PF15914.5 KDO20109.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 FAM193 family C-terminal Inhibitor_I29 PF08246.12 KDO20109.1 - 0.19 12.2 0.3 0.45 11.0 0.3 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) PT PF04886.12 KDO20109.1 - 0.27 10.8 9.4 0.55 9.8 9.4 1.4 1 0 0 1 1 1 0 PT repeat ABC_tran PF00005.27 KDO20110.1 - 2.4e-29 102.6 0.0 3.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO20110.1 - 2.3e-24 86.5 6.7 3.6e-24 85.9 6.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO20110.1 - 3.3e-08 33.2 0.0 0.00028 20.4 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO20110.1 - 7.4e-06 26.0 0.3 0.14 12.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO20110.1 - 0.00013 22.4 0.0 0.00034 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO20110.1 - 0.00037 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO20110.1 - 0.00067 19.9 0.6 0.058 13.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KDO20110.1 - 0.0016 19.0 0.0 0.0028 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO20110.1 - 0.003 17.2 0.0 0.063 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO20110.1 - 0.0034 17.3 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KDO20110.1 - 0.012 15.3 0.0 0.043 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_membrane_2 PF06472.15 KDO20110.1 - 0.023 14.1 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_15 PF13175.6 KDO20110.1 - 0.032 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KDO20110.1 - 0.04 13.8 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 KDO20110.1 - 0.071 13.3 0.0 0.27 11.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KDO20110.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 KDO20110.1 - 0.14 10.9 0.1 6.7 5.4 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Rad17 PF03215.15 KDO20110.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KDO20110.1 - 0.17 11.9 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Elicitin PF00964.17 KDO20111.1 - 0.0061 16.6 0.1 0.0076 16.3 0.1 1.2 1 0 0 1 1 1 1 Elicitin BT1 PF03092.16 KDO20114.1 - 1.1e-16 60.2 15.7 7e-16 57.6 1.8 2.4 2 1 0 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO20114.1 - 3.4e-08 32.8 44.8 2.4e-05 23.4 23.8 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KDO20114.1 - 0.00014 20.8 18.0 0.00014 20.8 18.0 2.4 1 1 1 2 2 2 1 MFS_1 like family DUF2085 PF09858.9 KDO20114.1 - 0.54 10.8 15.6 0.64 10.5 1.4 4.4 3 1 0 4 4 4 0 Predicted membrane protein (DUF2085) Phage_holin_2_1 PF04971.12 KDO20114.1 - 5.2 7.1 8.3 3.6 7.7 3.8 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S LRR_6 PF13516.6 KDO20115.1 - 1.1e-08 34.5 6.9 0.26 11.4 0.0 6.4 7 0 0 7 7 7 4 Leucine Rich repeat Ank_4 PF13637.6 KDO20116.1 - 0.0017 18.9 0.7 0.13 12.8 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) PHD PF00628.29 KDO20116.1 - 0.047 13.6 1.5 0.17 11.8 1.5 1.9 1 1 0 1 1 1 0 PHD-finger Ank_5 PF13857.6 KDO20116.1 - 0.075 13.4 0.5 21 5.6 0.0 3.7 3 2 1 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20116.1 - 0.12 13.0 0.0 2.4 8.8 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Prim_Zn_Ribbon PF08273.12 KDO20116.1 - 0.45 10.8 3.5 2 8.7 3.5 2.1 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Chordopox_L2 PF05803.12 KDO20117.1 - 0.24 11.3 3.7 0.44 10.4 0.1 2.7 2 0 0 2 2 2 0 Chordopoxvirus L2 protein YtpI PF14007.6 KDO20119.1 - 0.02 15.0 0.4 0.092 12.9 0.1 2.3 2 0 0 2 2 2 0 YtpI-like protein LRR_8 PF13855.6 KDO20121.1 - 1.1e-19 69.9 13.1 9.9e-09 34.8 1.5 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO20121.1 - 2.7e-10 40.3 1.0 0.00011 22.5 0.2 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO20121.1 - 9.7e-07 28.5 0.2 3 8.7 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRRNT_2 PF08263.12 KDO20121.1 - 0.024 15.0 4.9 0.061 13.6 4.9 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KDO20121.1 - 0.055 13.5 1.1 8.4 6.7 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat eIF2_C PF09173.11 KDO20122.1 - 2.4e-11 43.7 0.0 3.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 KDO20122.1 - 0.0009 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GSH-S_N PF02951.14 KDO20123.1 - 0.16 12.1 0.7 7.7 6.7 0.0 2.8 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain PAN_4 PF14295.6 KDO20126.1 - 1.6e-63 210.4 92.1 2e-09 37.2 3.3 10.0 9 0 0 9 9 9 9 PAN domain 3-dmu-9_3-mt PF06983.13 KDO20126.1 - 1.3e-05 25.7 16.6 5.8 7.5 0.1 7.1 7 1 0 7 7 7 2 3-demethylubiquinone-9 3-methyltransferase Sid-5 PF17204.3 KDO20126.1 - 0.00014 21.9 0.1 47 4.2 0.0 4.4 4 0 0 4 4 4 0 Sid-5 family CssAB PF16831.5 KDO20126.1 - 0.0016 18.8 7.2 18 5.7 0.0 5.8 6 0 0 6 6 6 2 CS6 fimbrial subunits A and B, Coli surface antigen 6 JAB PF01398.21 KDO20126.1 - 0.024 14.6 0.2 31 4.6 0.0 4.6 5 0 0 5 5 5 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Whib PF02467.16 KDO20126.1 - 0.12 12.9 42.1 3.3 8.4 0.2 8.9 9 0 0 9 9 9 0 Transcription factor WhiB MAR_sialic_bdg PF10564.9 KDO20126.1 - 0.51 10.4 65.3 1.1 9.3 1.1 9.1 9 0 0 9 9 9 0 Sialic-acid binding micronemal adhesive repeat LRR_4 PF12799.7 KDO20127.1 - 3.4e-05 24.1 7.6 0.07 13.6 0.7 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO20127.1 - 0.00013 21.8 13.4 15 6.0 0.0 6.8 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KDO20127.1 - 0.0011 19.3 10.3 9.9 7.2 0.0 6.8 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 KDO20127.1 - 0.3 10.9 16.6 9.2 6.1 0.9 5.6 5 1 1 6 6 6 0 Leucine rich repeat Elicitin PF00964.17 KDO20129.1 - 0.022 14.9 0.3 0.2 11.7 0.2 2.5 2 1 1 3 3 3 0 Elicitin MSA-2c PF12238.8 KDO20129.1 - 3.8 7.5 6.1 19 5.1 0.9 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Elicitin PF00964.17 KDO20130.1 - 2.2e-06 27.7 3.4 0.033 14.3 0.2 2.5 2 0 0 2 2 2 2 Elicitin Glycos_trans_3N PF02885.17 KDO20130.1 - 0.057 13.3 0.4 3 7.8 0.0 2.8 2 1 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Pkinase_Tyr PF07714.17 KDO20132.1 - 2e-52 178.1 0.0 2.6e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20132.1 - 7e-49 166.6 0.0 9.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO20132.1 - 5.5e-06 25.9 0.0 9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Crystall PF00030.19 KDO20132.1 - 8.5e-06 25.9 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 2 Beta/Gamma crystallin Pkinase_fungal PF17667.1 KDO20132.1 - 0.00016 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO20132.1 - 0.0028 17.6 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO20132.1 - 0.016 14.2 0.0 0.074 12.0 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Inhibitor_I36 PF03995.13 KDO20132.1 - 0.02 14.8 0.3 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 Peptidase inhibitor family I36 RskA PF10099.9 KDO20132.1 - 0.084 13.2 0.1 0.084 13.2 0.1 1.9 2 0 0 2 2 1 0 Anti-sigma-K factor rskA FTA2 PF13095.6 KDO20132.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KDO20132.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KDO20132.1 - 0.2 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 KDO20133.1 - 1.1e-15 58.0 3.9 5.2e-07 30.2 0.3 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20133.1 - 1.5e-15 57.3 9.0 0.00066 20.2 0.0 5.5 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20133.1 - 5.5e-13 48.9 5.0 0.022 15.1 0.1 6.2 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20133.1 - 1.2e-08 34.5 2.1 11 7.0 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 KDO20133.1 - 0.017 15.6 0.7 35 5.1 0.3 4.7 2 1 0 2 2 2 0 Ankyrin repeat ABC_tran PF00005.27 KDO20134.1 - 1.1e-26 94.0 0.0 2.2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO20134.1 - 4.7e-21 75.7 10.1 7.5e-21 75.0 10.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO20134.1 - 2.5e-06 27.1 0.8 0.0038 16.7 0.1 2.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO20134.1 - 5.1e-05 23.2 0.3 0.41 10.4 0.0 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO20134.1 - 0.00046 20.6 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO20134.1 - 0.00098 19.4 1.2 0.023 14.9 0.7 2.7 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 KDO20134.1 - 0.0028 17.3 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO20134.1 - 0.0034 17.3 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KDO20134.1 - 0.026 14.1 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_membrane_2 PF06472.15 KDO20134.1 - 0.039 13.3 3.0 0.2 11.0 3.1 2.1 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_23 PF13476.6 KDO20134.1 - 0.067 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO20134.1 - 0.076 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO20134.1 - 0.11 12.2 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KDO20134.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KDO20134.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KDO20134.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 KDO20134.1 - 0.17 12.3 0.1 2.4 8.6 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3817 PF12823.7 KDO20134.1 - 4 8.3 7.8 0.39 11.6 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3817) HD PF01966.22 KDO20135.1 - 1.3e-11 44.8 0.2 2.7e-11 43.7 0.2 1.6 1 0 0 1 1 1 1 HD domain LRR_6 PF13516.6 KDO20136.1 - 1.5e-05 24.6 18.4 0.03 14.3 0.0 6.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KDO20136.1 - 0.0052 17.2 2.1 0.78 10.3 0.2 4.2 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) UBM PF14377.6 KDO20136.1 - 0.054 12.9 0.4 0.74 9.4 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin binding region LRR_8 PF13855.6 KDO20136.1 - 0.17 11.7 0.0 0.17 11.7 0.0 3.4 3 1 0 3 3 3 0 Leucine rich repeat DUF2065 PF09838.9 KDO20136.1 - 0.8 9.8 4.0 24 5.0 0.3 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) LRR_4 PF12799.7 KDO20139.1 - 0.049 14.1 6.9 2.2 8.8 1.0 4.5 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) DUF3701 PF12482.8 KDO20139.1 - 0.054 13.6 0.2 0.15 12.1 0.2 1.8 1 0 0 1 1 1 0 Phage integrase protein DPBB_1 PF03330.18 KDO20140.1 - 4.7e-05 23.6 0.2 0.0001 22.5 0.2 1.6 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KDO20140.1 - 0.0025 17.7 1.4 0.0039 17.0 1.4 1.3 1 0 0 1 1 1 1 Barwin family Dpy-30 PF05186.13 KDO20141.1 - 3.1e-06 26.8 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 Dpy-30 motif Fanconi_C PF02106.15 KDO20141.1 - 0.051 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group C protein ArnB_C PF18677.1 KDO20141.1 - 0.84 9.8 3.4 3.7 7.7 0.2 3.2 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain MscS_porin PF12795.7 KDO20142.1 - 0.3 10.6 20.5 0.63 9.5 20.5 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GvpK PF05121.12 KDO20142.1 - 0.44 10.6 6.9 2.5 8.2 1.7 2.6 1 1 0 2 2 2 0 Gas vesicle protein K V_ATPase_I PF01496.19 KDO20142.1 - 1.3 6.8 7.0 2 6.3 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 KDO20142.1 - 1.9 8.8 5.1 7 7.0 4.7 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 KDO20142.1 - 2 7.7 13.2 3.3 7.0 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 KDO20142.1 - 2.1 8.8 13.5 0.34 11.3 8.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KDO20142.1 - 4.2 7.4 16.7 0.39 10.7 5.6 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YjbH PF06082.11 KDO20142.1 - 4.5 6.0 6.1 6.4 5.5 6.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH THOC7 PF05615.13 KDO20142.1 - 7.3 6.9 15.6 0.42 10.9 5.3 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 TPR_12 PF13424.6 KDO20143.1 - 1.8e-06 28.1 0.1 7.8e-05 22.9 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20143.1 - 0.014 15.3 0.4 7 6.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP13 PF12921.7 KDO20143.1 - 0.027 14.3 0.1 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATPase expression MNHE PF01899.16 KDO20144.1 - 0.34 10.7 1.3 16 5.2 0.0 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Ank_2 PF12796.7 KDO20145.1 - 1.6e-16 60.6 9.2 0.00012 22.6 0.0 5.4 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20145.1 - 2.6e-16 59.8 13.2 0.0026 18.3 0.2 7.8 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20145.1 - 7e-10 38.3 7.5 5.9 7.8 0.0 10.1 11 0 0 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 KDO20145.1 - 9.1e-08 32.2 11.8 0.49 10.8 0.6 8.5 4 2 6 10 10 10 2 Ankyrin repeats (many copies) Y2_Tnp PF04986.13 KDO20145.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DUF5049 PF16468.5 KDO20145.1 - 0.054 13.4 0.2 14 5.7 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5049) Abhydrolase_1 PF00561.20 KDO20146.1 - 8.6e-16 58.4 0.0 1.2e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO20146.1 - 6.6e-11 41.9 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO20146.1 - 1.1e-09 39.2 0.1 2.3e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KDO20146.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ank_2 PF12796.7 KDO20148.1 - 1.9e-12 47.6 9.3 2.1e-05 25.0 0.6 3.7 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20148.1 - 1.2e-07 32.1 12.2 0.0045 17.5 0.3 5.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20148.1 - 2.4e-06 27.4 7.0 16 6.5 0.1 7.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 KDO20148.1 - 0.0031 17.8 10.5 2.4 8.6 0.2 5.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) PH PF00169.29 KDO20149.1 - 2.2e-16 60.3 0.1 3.3e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO20149.1 - 1.6e-07 31.7 3.7 0.0047 17.3 0.1 3.9 4 1 0 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.6 KDO20149.1 - 4.7e-05 23.6 0.0 0.00013 22.1 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KDO20149.1 - 0.077 13.1 0.1 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 PH domain EMP24_GP25L PF01105.24 KDO20150.1 - 3.9e-17 62.8 2.1 2.1e-15 57.2 2.1 2.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ID PF18543.1 KDO20151.1 - 0.44 10.6 6.3 4.6 7.3 0.2 3.8 4 0 0 4 4 4 0 Intracellular delivery domain DUF3659 PF12396.8 KDO20151.1 - 2.6 8.0 32.4 3.4 7.6 7.1 5.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3659) TRP PF06011.12 KDO20152.1 - 0.0019 17.0 17.5 0.021 13.6 17.4 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel SIT PF15330.6 KDO20152.1 - 0.089 13.2 3.9 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMCO5 PF14992.6 KDO20154.1 - 0.012 15.2 3.3 0.02 14.5 3.3 1.4 1 0 0 1 1 1 0 TMCO5 family DUF3450 PF11932.8 KDO20154.1 - 0.012 14.9 2.5 0.024 13.9 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ALIX_LYPXL_bnd PF13949.6 KDO20154.1 - 0.062 12.6 5.0 0.14 11.4 5.0 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV ATG16 PF08614.11 KDO20154.1 - 0.14 12.4 10.7 0.23 11.7 10.4 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KDO20154.1 - 0.17 10.7 7.5 0.3 9.9 7.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FliT PF05400.13 KDO20154.1 - 0.43 11.4 2.7 1.1 10.2 1.2 2.2 2 1 0 2 2 2 0 Flagellar protein FliT DUF148 PF02520.17 KDO20154.1 - 0.52 10.4 10.5 0.066 13.3 5.1 2.2 2 1 1 3 3 3 0 Domain of unknown function DUF148 APG6_N PF17675.1 KDO20154.1 - 0.67 10.5 7.6 0.54 10.8 4.8 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 KDO20154.1 - 1.1 9.5 7.9 0.34 11.2 3.8 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.6 KDO20154.1 - 2.5 7.6 10.7 0.2 11.2 6.0 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 NDT80_PhoG PF05224.12 KDO20155.1 - 0.063 13.5 0.0 0.068 13.4 0.0 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family BLM10_mid PF16507.5 KDO20156.1 - 0.086 11.5 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region Myb_DNA-binding PF00249.31 KDO20157.1 - 0.0019 18.4 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO20158.1 - 3.5e-11 43.1 0.0 6.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20158.1 - 0.046 14.0 0.2 0.094 13.0 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PaREP1 PF05942.11 KDO20158.1 - 0.061 13.2 0.5 0.093 12.7 0.5 1.2 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Pkinase_Tyr PF07714.17 KDO20159.1 - 1.7e-46 158.6 0.0 4.1e-28 98.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO20159.1 - 3.3e-45 154.5 0.0 4.2e-31 108.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 KDO20159.1 - 1.4e-16 60.8 0.1 3.8e-08 33.8 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20159.1 - 4.3e-12 46.3 0.4 5.7e-05 23.6 0.0 4.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20159.1 - 1.2e-09 38.2 0.3 2.9e-05 24.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO20159.1 - 1.1e-07 32.0 6.3 0.021 15.2 0.0 5.4 6 0 0 6 6 5 2 Ankyrin repeat Ank_3 PF13606.6 KDO20159.1 - 3.7e-07 29.9 0.6 0.55 11.0 0.0 6.0 6 0 0 6 6 5 1 Ankyrin repeat Pkinase_fungal PF17667.1 KDO20159.1 - 0.00012 21.0 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO20159.1 - 0.01 15.2 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KDO20159.1 - 0.025 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO20159.1 - 0.1 12.5 3.1 0.91 9.4 0.4 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family zf-tcix PF14952.6 KDO20159.1 - 0.12 12.0 2.0 0.34 10.6 2.0 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Kdo PF06293.14 KDO20159.1 - 0.25 10.7 1.4 2.1 7.6 0.4 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.6 KDO20159.1 - 1.4 8.4 9.3 12 5.5 0.7 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Ank_2 PF12796.7 KDO20160.1 - 1.5e-23 83.1 9.0 1.3e-11 44.9 0.4 3.2 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20160.1 - 4.1e-11 43.2 0.2 2.7e-05 24.6 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20160.1 - 2.2e-10 39.8 1.7 0.004 17.5 0.0 5.4 6 0 0 6 6 4 3 Ankyrin repeat Ank PF00023.30 KDO20160.1 - 1.1e-09 38.3 10.6 0.0017 18.7 0.2 5.1 4 1 1 5 5 4 2 Ankyrin repeat Pkinase PF00069.25 KDO20160.1 - 9.4e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 KDO20160.1 - 2.1e-08 34.2 5.7 6.2e-07 29.6 0.3 3.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO20160.1 - 7.7e-08 31.9 0.0 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C4pol PF14260.6 KDO20160.1 - 0.036 14.5 7.8 0.23 12.0 1.1 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 KDO20160.1 - 0.28 11.2 11.3 1.8 8.7 11.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KDO20160.1 - 1.6 8.8 8.8 4.7 7.3 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbons NOB1_Zn_bind PF08772.11 KDO20160.1 - 4.2 7.6 10.8 1.2 9.4 2.3 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-CHY PF05495.12 KDO20160.1 - 5.5 7.6 11.0 1.2 9.6 0.6 2.3 1 1 1 2 2 2 0 CHY zinc finger HypA PF01155.19 KDO20160.1 - 5.9 7.0 10.5 8 6.5 5.6 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pkinase_Tyr PF07714.17 KDO20161.1 - 3.1e-52 177.4 0.0 4.3e-24 85.2 0.0 4.0 3 2 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KDO20161.1 - 1.3e-51 175.5 0.0 1.9e-26 93.0 0.0 3.8 3 2 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 KDO20161.1 - 0.0011 18.3 0.3 10 5.4 0.0 3.3 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO20161.1 - 0.0053 16.4 0.0 0.21 11.2 0.0 2.8 3 0 0 3 3 3 1 RIO1 family FTA2 PF13095.6 KDO20161.1 - 0.027 14.1 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_5 PF13857.6 KDO20161.1 - 0.051 13.9 0.2 5.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Kinase-like PF14531.6 KDO20161.1 - 0.18 11.1 0.3 47 3.1 0.0 3.0 3 0 0 3 3 3 0 Kinase-like NESP55 PF06390.12 KDO20162.1 - 0.19 11.3 11.4 0.058 13.0 8.1 1.8 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 KDO20162.1 - 0.71 9.9 7.9 1.3 9.0 7.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RVT_2 PF07727.14 KDO20166.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KDO20167.1 - 6e-15 55.2 0.0 2.7e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20167.1 - 3.5e-11 43.0 0.0 1.6e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20168.1 - 5.1e-14 52.2 0.0 1.2e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20168.1 - 1e-09 38.1 0.0 3.8e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain zinc_ribbon_2 PF13240.6 KDO20168.1 - 0.29 10.9 3.4 4.7 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KDO20168.1 - 0.45 10.0 6.4 6.4 6.3 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KDO20168.1 - 7.7 6.8 7.4 17 5.7 0.3 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Pkinase PF00069.25 KDO20169.1 - 1.7e-34 119.4 0.0 4.1e-32 111.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20169.1 - 1e-32 113.5 0.0 7.7e-30 104.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO20169.1 - 0.00028 20.0 0.0 0.00036 19.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO20169.1 - 0.0025 17.8 0.1 0.12 12.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO20169.1 - 0.0032 16.8 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO20169.1 - 0.0039 16.0 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO20169.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ank_2 PF12796.7 KDO20170.1 - 2.3e-64 214.0 31.2 7.6e-15 55.3 3.3 7.4 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20170.1 - 4.9e-49 164.1 18.3 1.8e-08 34.7 0.1 9.6 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20170.1 - 4.6e-46 149.5 22.7 0.00052 20.3 0.1 14.2 14 0 0 14 14 14 11 Ankyrin repeat Ank PF00023.30 KDO20170.1 - 1.1e-37 126.8 38.9 1.4e-05 25.4 0.4 14.6 13 1 1 14 14 14 10 Ankyrin repeat Pkinase PF00069.25 KDO20170.1 - 1.1e-35 123.3 0.0 4.9e-34 117.9 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Ank_5 PF13857.6 KDO20170.1 - 2.4e-35 120.1 32.1 3e-08 33.8 1.4 10.1 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO20170.1 - 8.6e-30 103.9 0.0 4.2e-28 98.3 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO20170.1 - 0.0043 15.9 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO20170.1 - 0.0055 16.1 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20170.1 - 0.0059 16.0 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO20170.1 - 0.22 10.4 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KDO20171.1 - 1.7e-15 57.0 0.0 6.6e-15 55.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20171.1 - 7e-11 42.0 0.0 3.3e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO20171.1 - 0.064 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIIC_sub6 PF10419.9 KDO20174.1 - 4.6e-11 42.5 0.0 6.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain BLACT_WH PF17778.1 KDO20175.1 - 1.8e-10 40.7 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain W2 PF02020.18 KDO20176.1 - 1.8e-19 69.6 0.9 3.2e-19 68.9 0.9 1.4 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon MRG PF05712.13 KDO20176.1 - 0.0037 16.6 0.1 1 8.6 0.0 2.1 1 1 1 2 2 2 2 MRG LktC PF06261.11 KDO20176.1 - 0.072 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC HAGH_C PF16123.5 KDO20177.1 - 8.3e-25 87.1 0.1 1.2e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KDO20177.1 - 1.4e-10 41.5 5.8 1.4e-10 41.5 5.8 2.4 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO20177.1 - 0.077 12.5 5.6 0.1 12.1 0.5 2.7 2 1 0 2 2 2 0 Beta-lactamase superfamily domain RCC1 PF00415.18 KDO20178.1 - 3.9e-56 187.5 15.3 9.8e-13 48.5 0.2 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO20178.1 - 6.7e-20 70.4 43.6 5.7e-05 22.8 3.1 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat zf-RING_2 PF13639.6 KDO20178.1 - 4.5e-09 36.5 11.1 4.5e-09 36.5 11.1 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KDO20178.1 - 5.6e-07 29.8 8.2 1.7e-06 28.2 8.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KDO20178.1 - 2.1e-05 24.3 3.4 2.1e-05 24.3 3.4 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KDO20178.1 - 0.00032 20.5 10.6 0.00032 20.5 10.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO20178.1 - 0.00033 20.4 8.7 0.00033 20.4 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO20178.1 - 0.00057 19.7 10.8 0.00057 19.7 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO20178.1 - 0.00076 19.5 3.9 0.00076 19.5 3.9 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO20178.1 - 0.01 15.8 11.9 0.01 15.8 11.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO20178.1 - 0.054 13.6 4.4 0.17 12.0 4.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 KDO20178.1 - 0.061 12.7 1.8 0.099 12.0 1.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3246 PF11596.8 KDO20178.1 - 0.19 11.1 3.2 0.34 10.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DivIC PF04977.15 KDO20178.1 - 0.43 10.4 3.1 0.74 9.6 2.5 1.8 1 1 0 1 1 1 0 Septum formation initiator zf-C3HC4_4 PF15227.6 KDO20178.1 - 0.65 10.2 14.0 0.15 12.2 8.0 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KDO20178.1 - 0.67 9.8 4.5 1.5 8.7 4.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4611 PF15387.6 KDO20178.1 - 0.83 9.9 3.6 2 8.7 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-RING_11 PF17123.5 KDO20178.1 - 1.3 8.9 10.9 3.6 7.4 7.9 2.8 2 0 0 2 2 2 0 RING-like zinc finger ARL2_Bind_BART PF11527.8 KDO20179.1 - 1.4e-17 63.9 1.2 1.6e-17 63.7 1.2 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Hydrolase_4 PF12146.8 KDO20180.1 - 6.9e-13 48.4 0.2 8.7e-13 48.1 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO20180.1 - 4.7e-11 42.8 0.1 6.2e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO20180.1 - 3.6e-07 31.0 4.9 5.5e-07 30.4 4.9 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KDO20180.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Asp2 PF16929.5 KDO20180.1 - 0.01 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Esterase PF00756.20 KDO20180.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF5399 PF17377.2 KDO20181.1 - 8.7 6.2 5.8 3.2 7.6 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5399) DUF2798 PF11391.8 KDO20182.1 - 1.4 9.0 3.7 1.1 9.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) EF-hand_1 PF00036.32 KDO20183.1 - 2.2e-10 39.3 0.1 4.6e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO20183.1 - 2.3e-09 37.5 0.1 2.5e-07 31.0 0.0 2.5 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO20183.1 - 1.4e-07 30.7 0.5 0.0062 16.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO20183.1 - 1.9e-06 27.3 2.0 0.06 13.3 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KDO20183.1 - 2.7e-05 23.9 0.4 0.00012 21.9 0.2 2.3 1 1 1 2 2 2 1 EF-hand domain pair DUF2827 PF10933.8 KDO20183.1 - 0.13 11.0 0.2 0.23 10.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Ank_2 PF12796.7 KDO20184.1 - 0.0057 17.2 0.0 0.0081 16.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO20184.1 - 0.075 13.6 0.0 20 6.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat UPRTase PF14681.6 KDO20186.1 - 0.0039 16.7 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DSPn PF14671.6 KDO20188.1 - 1.3e-32 113.2 0.3 1.5e-32 113.0 0.3 1.0 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Metallophos PF00149.28 KDO20189.1 - 1.5e-16 61.5 1.9 2.8e-16 60.6 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO20189.1 - 5.2e-09 36.8 0.2 1.7e-08 35.2 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KDO20189.1 - 1.1e-07 32.3 0.4 2.6e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 KDO20189.1 - 0.00023 21.4 0.1 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.31 KDO20190.1 - 5.1e-11 42.6 0.0 7.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDZ_2 PF13180.6 KDO20191.1 - 0.092 13.1 0.1 15 6.0 0.0 2.3 2 0 0 2 2 2 0 PDZ domain ubiquitin PF00240.23 KDO20196.1 - 8.6e-34 115.1 0.4 1.1e-33 114.8 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO20196.1 - 1.5e-15 56.8 0.7 1.9e-15 56.4 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO20196.1 - 3.1e-05 24.4 0.1 0.00013 22.4 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO20196.1 - 0.00065 19.8 0.4 0.0019 18.3 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KDO20196.1 - 0.0091 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KDO20196.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KDO20196.1 - 0.023 15.3 1.0 0.035 14.7 0.9 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KDO20196.1 - 0.17 11.9 0.7 9.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 KDO20196.1 - 0.33 9.6 2.5 0.56 8.8 0.1 1.9 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Nnf1 PF03980.14 KDO20197.1 - 3.2e-10 40.4 4.5 6e-10 39.5 4.5 1.4 1 0 0 1 1 1 1 Nnf1 DUF4164 PF13747.6 KDO20197.1 - 0.12 12.7 6.4 1.6 9.1 2.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) TPR_1 PF00515.28 KDO20198.1 - 1e-23 82.1 13.9 1e-05 25.1 1.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20198.1 - 8.9e-23 78.5 15.9 0.00041 20.3 0.6 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_9 PF13371.6 KDO20198.1 - 2.9e-09 36.9 2.9 1.9e-05 24.7 1.1 2.9 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20198.1 - 8.5e-09 35.0 12.7 3e-07 30.0 0.8 5.0 5 2 2 7 7 7 1 TPR repeat TPR_8 PF13181.6 KDO20198.1 - 2.9e-08 33.3 13.7 0.093 13.0 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20198.1 - 9.6e-08 32.2 12.1 0.00021 21.5 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20198.1 - 6.3e-06 26.7 8.5 0.08 13.6 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20198.1 - 7.4e-06 26.0 5.1 2.7 8.6 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20198.1 - 1.6e-05 25.4 10.3 4.1 8.5 0.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20198.1 - 6.4e-05 22.7 8.7 2.8 8.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO20198.1 - 0.00025 21.0 8.3 4.7 7.4 0.1 4.7 5 0 0 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat MscS_porin PF12795.7 KDO20198.1 - 0.27 10.8 1.8 0.25 10.8 0.4 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TPR_19 PF14559.6 KDO20198.1 - 0.6 10.7 8.4 5.4 7.6 0.3 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KDO20198.1 - 1.1 9.4 9.0 17 5.6 1.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KDO20198.1 - 6.7 7.6 14.3 6.2 7.7 0.7 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TEBP_beta PF07404.11 KDO20199.1 - 0.034 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Cadherin-like PF12733.7 KDO20199.1 - 0.049 14.2 0.1 12 6.5 0.0 2.4 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain Cellulase PF00150.18 KDO20201.1 - 2e-10 40.6 4.9 4.3e-10 39.5 4.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 KDO20201.1 - 6.1e-08 33.2 2.3 1.7e-07 31.8 2.3 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_42 PF02449.15 KDO20201.1 - 3e-05 23.5 2.7 0.065 12.6 1.4 2.1 2 0 0 2 2 2 2 Beta-galactosidase AP_endonuc_2 PF01261.24 KDO20201.1 - 0.0037 16.7 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel IL17R_fnIII_D1 PF16556.5 KDO20201.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 Glyco_hydro_2_C PF02836.17 KDO20201.1 - 0.06 12.4 0.4 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain MAPEG PF01124.18 KDO20202.1 - 5.9e-05 23.0 5.6 8.3e-05 22.5 5.2 1.5 1 1 0 1 1 1 1 MAPEG family WD40 PF00400.32 KDO20203.1 - 2.5e-08 34.4 6.3 0.0066 17.3 0.1 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20203.1 - 3.1e-05 24.2 0.0 0.012 15.9 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KDO20203.1 - 0.063 13.8 0.9 7.4 7.2 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain Voltage_CLC PF00654.20 KDO20203.1 - 1.1 8.4 9.5 2.2 7.5 9.5 1.4 1 0 0 1 1 1 0 Voltage gated chloride channel Tmemb_161AB PF10268.9 KDO20205.1 - 1.6e-41 142.5 1.0 2.2e-41 142.0 1.0 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB COMM_domain PF07258.14 KDO20206.1 - 3.1e-05 24.0 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 COMM domain DUF3022 PF11226.8 KDO20206.1 - 0.017 15.5 0.2 0.029 14.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Myb_DNA-binding PF00249.31 KDO20207.1 - 1.3e-12 47.7 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20207.1 - 0.022 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO20208.1 - 0.003 17.7 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4203 PF13886.6 KDO20209.1 - 1.6e-17 63.8 6.7 1.8e-17 63.7 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4381 PF14316.6 KDO20209.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3487 PF11990.8 KDO20209.1 - 0.27 11.1 3.4 14 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF308 PF03729.13 KDO20209.1 - 5 7.5 12.9 90 3.5 12.9 2.1 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF4203 PF13886.6 KDO20210.1 - 1.1e-33 116.6 29.4 3e-33 115.2 29.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2374 PF09574.10 KDO20210.1 - 0.031 14.1 0.9 0.031 14.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) DUF4381 PF14316.6 KDO20210.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) DUF4203 PF13886.6 KDO20212.1 - 1.2e-24 87.1 34.5 5.7e-22 78.4 15.9 2.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4203) DUF4131 PF13567.6 KDO20212.1 - 2 8.0 21.4 0.23 11.1 0.7 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) DUF4690 PF15756.5 KDO20212.1 - 6.4 7.5 5.4 3.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF4203 PF13886.6 KDO20213.1 - 5.2e-20 72.0 31.4 1.7e-14 54.0 6.1 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4203) DUF443 PF04276.12 KDO20213.1 - 0.19 11.5 2.3 0.31 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF443) DUF4203 PF13886.6 KDO20214.1 - 9.6e-39 133.1 33.4 1.1e-38 132.9 33.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Robl_LC7 PF03259.17 KDO20219.1 - 0.0012 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain SUR7 PF06687.12 KDO20221.1 - 0.00056 19.6 13.9 0.0019 17.9 13.9 1.9 1 1 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 KDO20221.1 - 5.9 5.5 6.6 0.37 9.5 1.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NodS PF05401.11 KDO20222.1 - 0.0097 15.5 0.5 0.015 14.9 0.5 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ndc1_Nup PF09531.10 KDO20222.1 - 0.13 11.0 2.0 0.18 10.5 2.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_holin_2_4 PF16082.5 KDO20222.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.4 3 1 0 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF4690 PF15756.5 KDO20222.1 - 0.24 12.0 2.6 4.2 8.0 0.3 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage WD40 PF00400.32 KDO20223.1 - 1.8e-20 72.9 0.9 7e-08 33.0 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20223.1 - 2.1e-09 37.6 0.7 0.025 14.8 0.0 3.6 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO20223.1 - 0.0016 17.2 0.0 0.02 13.6 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KDO20223.1 - 0.15 10.8 0.0 4.7 5.8 0.0 2.3 3 0 0 3 3 3 0 Nup133 N terminal like PI3_PI4_kinase PF00454.27 KDO20224.1 - 4.2e-28 98.8 0.0 1e-27 97.5 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KDO20224.1 - 0.0057 16.5 2.0 0.0061 16.3 0.2 2.1 2 0 0 2 2 2 1 FATC domain eIF3_subunit PF08597.10 KDO20225.1 - 1.5e-37 129.8 13.0 1.8e-37 129.5 13.0 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ProRS-C_1 PF09180.11 KDO20225.1 - 0.01 16.0 0.4 0.022 15.0 0.4 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal TPR_2 PF07719.17 KDO20226.1 - 4.4e-09 35.8 0.0 0.081 13.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20226.1 - 0.00011 22.8 0.0 0.00011 22.8 0.0 3.9 4 1 0 4 4 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO20226.1 - 0.0002 21.4 3.7 0.00062 19.9 1.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20226.1 - 0.00039 20.4 0.1 6.1 7.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20226.1 - 0.00044 20.0 0.0 8.1 6.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20226.1 - 0.00075 19.1 0.0 0.12 12.1 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 KDO20226.1 - 0.0016 18.3 0.4 4.9 7.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20226.1 - 0.0052 17.0 3.0 0.96 9.8 0.3 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KDO20226.1 - 0.0085 16.4 0.6 0.06 13.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20226.1 - 0.025 15.0 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20226.1 - 0.034 14.9 19.2 0.079 13.8 0.0 6.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO20226.1 - 0.1 12.8 0.2 0.56 10.5 0.0 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Marek_SORF3 PF07153.11 KDO20226.1 - 0.3 10.4 3.4 0.21 10.9 1.1 1.9 2 1 0 2 2 2 0 Marek's disease-like virus SORF3 protein Nterm_IS4 PF13006.7 KDO20226.1 - 0.34 11.1 5.3 0.26 11.5 0.7 2.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal TPR_19 PF14559.6 KDO20226.1 - 0.44 11.1 11.5 0.32 11.5 0.1 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.27 KDO20227.1 - 4.1e-19 68.3 6.2 8.2e-07 28.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0054 PF02130.17 KDO20228.1 - 4.3e-29 100.9 0.0 5.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DUF3810 PF12725.7 KDO20228.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) 2OG-FeII_Oxy_2 PF13532.6 KDO20229.1 - 6.8e-36 124.3 0.0 1.4e-35 123.3 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KDO20229.1 - 0.0021 18.5 0.0 0.0051 17.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TFIIA PF03153.13 KDO20230.1 - 3 7.8 22.8 3.9 7.4 22.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NDUFB10 PF10249.9 KDO20231.1 - 0.00018 22.0 0.0 0.00019 22.0 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 SNF2_N PF00176.23 KDO20232.1 - 1.1e-70 238.2 0.2 3.3e-70 236.5 0.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KDO20232.1 - 4.2e-08 32.9 8.4 4.2e-08 32.9 8.4 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO20232.1 - 4.1e-06 26.5 9.1 1.6e-05 24.7 8.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO20232.1 - 5.3e-05 23.1 6.9 5.3e-05 23.1 6.9 3.3 4 0 0 4 4 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KDO20232.1 - 8.8e-05 22.8 9.2 8.8e-05 22.8 9.2 3.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO20232.1 - 0.00035 20.4 8.3 0.00035 20.4 8.3 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO20232.1 - 0.00082 19.2 8.9 0.0059 16.4 8.9 2.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO20232.1 - 0.011 15.8 6.8 0.057 13.5 6.8 2.4 1 0 0 1 1 1 0 RING-type zinc-finger Adeno_E4_ORF3 PF06931.11 KDO20232.1 - 0.021 15.0 0.1 0.059 13.6 0.1 1.7 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein Gin PF10764.9 KDO20232.1 - 0.078 13.0 0.8 0.4 10.7 0.7 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-P11 PF03854.14 KDO20232.1 - 0.88 9.3 5.6 5.3 6.8 5.5 2.4 1 1 1 2 2 2 0 P-11 zinc finger Ank_5 PF13857.6 KDO20233.1 - 1.3e-05 25.4 0.1 6.4e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RGS PF00615.19 KDO20233.1 - 0.00028 21.2 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ank_2 PF12796.7 KDO20233.1 - 0.0005 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20233.1 - 0.01 16.4 0.1 4.5 8.0 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeats (many copies) TPR_8 PF13181.6 KDO20233.1 - 0.015 15.4 0.1 0.053 13.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20233.1 - 0.018 15.8 0.2 0.018 15.8 0.2 4.4 3 2 1 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20233.1 - 0.023 14.7 0.9 1 9.6 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_3 PF13606.6 KDO20233.1 - 0.042 14.4 0.1 1.2 10.0 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat TPR_2 PF07719.17 KDO20233.1 - 0.069 13.3 2.0 0.35 11.1 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 KDO20233.1 - 0.096 12.9 2.1 0.12 12.7 0.5 2.0 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_6 PF13174.6 KDO20233.1 - 0.12 13.0 0.5 0.12 13.0 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KDO20233.1 - 0.18 12.2 10.8 0.36 11.2 0.7 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20233.1 - 0.44 11.1 5.4 0.61 10.6 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20233.1 - 0.66 10.3 9.9 0.11 12.8 3.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO20233.1 - 4 8.4 7.5 4.5 8.2 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L32p PF01783.23 KDO20234.1 - 2.7e-10 40.4 5.4 3.9e-10 39.8 5.4 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family Sds3 PF08598.11 KDO20235.1 - 4.5e-07 30.1 2.4 4.5e-07 30.1 2.4 1.6 2 0 0 2 2 2 1 Sds3-like PUF PF00806.19 KDO20236.1 - 1e-11 43.8 0.0 0.36 10.6 0.0 7.8 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat ACOX PF01756.19 KDO20236.1 - 0.018 14.6 0.4 6.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Acyl-CoA oxidase PH PF00169.29 KDO20237.1 - 0.048 14.2 0.0 0.089 13.3 0.0 1.4 1 0 0 1 1 1 0 PH domain DUF3663 PF12404.8 KDO20237.1 - 0.2 11.7 0.8 0.37 10.9 0.1 1.8 2 0 0 2 2 2 0 Peptidase DSPc PF00782.20 KDO20238.1 - 1.5e-43 147.8 0.1 8.2e-25 87.2 0.1 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain FYVE PF01363.21 KDO20238.1 - 8.3e-11 41.9 7.9 2.3e-10 40.5 7.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger Rhodanese PF00581.20 KDO20238.1 - 3.3e-06 27.6 0.0 3.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KDO20238.1 - 6.2e-05 22.7 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase FYVE_2 PF02318.16 KDO20238.1 - 0.0019 18.4 1.8 0.0039 17.4 1.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger PTPlike_phytase PF14566.6 KDO20238.1 - 0.043 13.9 0.0 7.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate CAP_N PF01213.19 KDO20239.1 - 0.25 10.8 3.9 0.28 10.6 0.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SecY PF00344.20 KDO20240.1 - 4.3e-58 197.0 14.3 5.4e-58 196.7 14.3 1.0 1 0 0 1 1 1 1 SecY translocase p450 PF00067.22 KDO20241.1 - 1.4e-54 185.6 0.0 1.6e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TnsD PF15978.5 KDO20243.1 - 0.037 13.0 0.1 0.039 13.0 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D SapC PF07277.11 KDO20243.1 - 0.076 12.6 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 SapC Autoind_bind PF03472.15 KDO20246.1 - 0.065 12.7 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Myb_DNA-binding PF00249.31 KDO20247.1 - 0.00011 22.3 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain PRRSV_Env PF02340.15 KDO20248.1 - 0.053 12.9 0.1 0.098 12.0 0.1 1.5 1 0 0 1 1 1 0 PRRSV putative envelope protein IRF-2BP1_2 PF11261.8 KDO20248.1 - 0.21 11.2 0.4 0.47 10.1 0.4 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Myb_DNA-binding PF00249.31 KDO20252.1 - 2.8e-10 40.2 0.1 5.6e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20252.1 - 0.019 15.2 0.2 0.036 14.3 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO20253.1 - 3.3e-11 43.2 0.0 6.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain OrfB_IS605 PF01385.19 KDO20253.1 - 0.023 14.9 1.4 0.037 14.2 1.4 1.3 1 0 0 1 1 1 0 Probable transposase Myb_DNA-bind_6 PF13921.6 KDO20253.1 - 0.039 14.2 0.2 0.094 13.0 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain PaREP1 PF05942.11 KDO20253.1 - 0.045 13.7 0.3 0.068 13.1 0.3 1.2 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family LAMTOR PF15454.6 KDO20253.1 - 0.058 14.0 0.4 0.14 12.8 0.0 1.8 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3772 PF12607.8 KDO20254.1 - 0.0014 18.3 3.0 12 5.8 0.0 3.9 1 1 3 4 4 4 4 Protein of unknown function (DUF3772) BLM10_mid PF16507.5 KDO20255.1 - 0.071 11.7 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region NDT80_PhoG PF05224.12 KDO20256.1 - 0.049 13.8 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family TRP PF06011.12 KDO20259.1 - 0.00086 18.1 21.3 0.011 14.5 21.3 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel SIT PF15330.6 KDO20259.1 - 0.45 11.0 4.5 6.5 7.2 0.1 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Beta-lactamase PF00144.24 KDO20260.1 - 1.4e-38 133.0 0.2 2.1e-38 132.4 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO20260.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KDO20261.1 - 5.5e-44 150.8 1.0 8.7e-44 150.1 1.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO20261.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KDO20263.1 - 2.2e-42 145.5 0.4 3.4e-42 144.9 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO20263.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family M16C_assoc PF08367.11 KDO20264.1 - 7.5e-61 205.4 0.2 1.4e-60 204.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KDO20264.1 - 3.1e-19 69.7 0.1 1.3e-13 51.3 0.0 3.7 3 1 2 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KDO20264.1 - 1.2e-10 41.6 0.3 2.4e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF3618 PF12277.8 KDO20264.1 - 4.8 7.5 6.9 0.45 10.8 0.3 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) ISN1 PF06437.11 KDO20265.1 - 2.9e-96 322.9 0.0 3.6e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Peptidase_S74 PF13884.6 KDO20267.1 - 1.3e-15 57.5 0.0 2.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Stomoxyn PF11585.8 KDO20267.1 - 2.9 8.0 7.1 2.2 8.4 3.3 2.6 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn DUF1173 PF06666.11 KDO20269.1 - 0.086 11.8 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Ank_2 PF12796.7 KDO20270.1 - 1.9e-31 108.5 17.9 9e-08 32.6 0.2 5.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20270.1 - 2.7e-28 97.6 31.3 0.089 13.1 0.0 13.0 2 2 11 13 13 13 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20270.1 - 1.9e-27 95.3 25.7 0.00028 21.4 0.5 10.2 6 2 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20270.1 - 1.7e-16 58.6 9.9 9 7.2 0.0 12.0 11 2 2 13 13 13 2 Ankyrin repeat DUF5049 PF16468.5 KDO20270.1 - 1e-05 25.3 0.3 2.7 8.0 0.0 6.7 6 2 4 10 10 10 2 Domain of unknown function (DUF5049) Ank PF00023.30 KDO20270.1 - 0.00011 22.5 11.2 1.3e+02 3.3 0.3 9.5 2 1 2 4 4 4 0 Ankyrin repeat DUF3322 PF11795.8 KDO20270.1 - 0.0012 18.9 0.2 0.95 9.4 0.0 3.9 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DLH PF01738.18 KDO20271.1 - 2.2e-11 43.7 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KDO20271.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Myosin_head PF00063.21 KDO20272.1 - 3e-211 703.2 0.0 4.8e-211 702.6 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KDO20272.1 - 4.1e-14 51.0 27.2 6.8e-05 22.3 0.4 5.8 5 0 0 5 5 5 4 IQ calmodulin-binding motif WW PF00397.26 KDO20272.1 - 1.8e-07 31.1 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 WW domain AAA_16 PF13191.6 KDO20272.1 - 0.0056 17.1 5.2 0.014 15.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KDO20272.1 - 0.023 15.0 0.4 0.16 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KDO20272.1 - 0.13 11.7 1.9 6.2 6.2 1.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF4768 PF15989.5 KDO20272.1 - 1.1 9.2 3.8 0.58 10.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4768) AAA_19 PF13245.6 KDO20272.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.8 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KDO20272.1 - 2.1 8.8 5.2 0.84 10.1 0.2 2.8 2 2 0 2 2 2 0 ABC transporter Cep57_CLD_2 PF14197.6 KDO20272.1 - 2.1 8.5 9.0 0.19 11.8 1.0 3.3 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 KDO20272.1 - 2.4 8.2 10.2 5.2 7.1 10.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 5_3_exonuc PF01367.20 KDO20272.1 - 2.4 8.8 4.2 0.87 10.2 0.2 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold AAA_18 PF13238.6 KDO20272.1 - 3 8.4 4.4 1.1 9.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain PNP_phzG_C PF10590.9 KDO20276.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DUF384 PF04064.13 KDO20277.1 - 0.054 13.3 0.8 0.17 11.7 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF384) HTH_12 PF08461.10 KDO20277.1 - 0.071 13.1 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain PGM_PMM_III PF02880.16 KDO20277.1 - 0.073 13.3 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III HTH_12 PF08461.10 KDO20279.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Pox_E10 PF04805.12 KDO20279.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 E10-like protein conserved region DIOX_N PF14226.6 KDO20280.1 - 6.2e-24 85.0 0.0 8.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO20280.1 - 2e-21 76.4 0.0 4.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cyclin_N PF00134.23 KDO20281.1 - 1.4e-34 118.5 3.6 2.6e-34 117.7 0.6 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO20281.1 - 2.8e-23 82.2 1.5 2.8e-23 82.2 1.5 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain PUB PF09409.10 KDO20282.1 - 8.8e-18 64.0 0.0 1.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 PUB domain DUF899 PF05988.12 KDO20282.1 - 0.02 14.4 0.6 0.033 13.7 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Vma12 PF11712.8 KDO20282.1 - 0.59 10.2 4.7 18 5.4 4.6 2.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CAP_N PF01213.19 KDO20282.1 - 2.6 7.4 14.4 1.1 8.7 8.8 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal VIR_N PF15912.5 KDO20282.1 - 9.4 5.7 10.2 3.3 7.3 6.5 1.9 2 0 0 2 2 2 0 Virilizer, N-terminal PLAC8 PF04749.17 KDO20283.1 - 6e-16 59.2 7.1 7.8e-16 58.9 7.1 1.1 1 0 0 1 1 1 1 PLAC8 family PhoR PF11808.8 KDO20283.1 - 0.41 11.1 2.5 0.88 10.0 2.5 1.5 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR FixQ PF05545.11 KDO20283.1 - 1.8 8.6 4.7 0.84 9.7 2.2 1.7 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4763 PF15960.5 KDO20284.1 - 0.33 10.2 11.8 0.023 14.0 6.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) TPH PF13868.6 KDO20284.1 - 5.3 5.4 32.9 0.1 11.1 17.8 2.1 2 0 0 2 2 2 0 Trichohyalin-plectin-homology domain RRM_1 PF00076.22 KDO20285.1 - 3.1e-11 42.9 0.0 3.1e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB_2 PF02214.22 KDO20286.1 - 5e-09 36.4 0.0 4.8e-08 33.2 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain LRR_8 PF13855.6 KDO20287.1 - 1.6e-08 34.2 0.0 0.0025 17.5 0.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO20287.1 - 0.00052 20.3 0.0 0.0079 16.6 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO20288.1 - 3e-09 36.5 0.0 0.0057 16.4 0.0 3.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO20288.1 - 0.00045 20.6 0.0 0.013 15.9 0.0 3.3 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO20288.1 - 0.039 14.5 0.1 60 4.8 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO20288.1 - 0.87 9.8 4.7 40 4.6 0.0 4.6 7 0 0 7 7 7 0 Leucine Rich repeat PLAC8 PF04749.17 KDO20289.1 - 2.1e-17 63.9 9.4 2.9e-17 63.5 9.4 1.2 1 0 0 1 1 1 1 PLAC8 family LapA_dom PF06305.11 KDO20289.1 - 0.0047 16.7 1.4 0.0078 16.0 1.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain zf-C3HC4_2 PF13923.6 KDO20290.1 - 1.5e-08 34.3 15.7 2.5e-08 33.6 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO20290.1 - 3.1e-06 26.9 14.7 5.5e-06 26.1 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO20290.1 - 2.4e-05 24.5 14.7 5.2e-05 23.5 14.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO20290.1 - 8.1e-05 22.4 13.4 0.00013 21.8 13.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO20290.1 - 0.00079 19.4 11.5 0.0021 18.0 10.6 2.2 2 1 0 2 2 2 1 RING-type zinc-finger GAGA PF09237.11 KDO20290.1 - 0.0094 15.7 2.3 0.73 9.7 0.2 2.4 2 0 0 2 2 2 1 GAGA factor zf-RING_6 PF14835.6 KDO20290.1 - 0.013 15.4 7.4 0.021 14.7 7.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KDO20290.1 - 0.024 14.6 12.9 0.049 13.6 12.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Siva PF05458.12 KDO20290.1 - 0.057 13.1 8.6 0.092 12.4 8.6 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF326 PF03860.16 KDO20290.1 - 0.093 12.7 2.2 0.2 11.7 2.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) zf-C3HC4_4 PF15227.6 KDO20290.1 - 0.12 12.5 12.4 0.29 11.3 12.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KDO20290.1 - 0.16 11.8 7.0 0.27 11.1 7.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 KDO20290.1 - 3.9 7.4 12.4 13 5.8 12.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PLAC8 PF04749.17 KDO20291.1 - 6.1e-17 62.4 14.4 7.6e-17 62.1 14.4 1.1 1 0 0 1 1 1 1 PLAC8 family CCSMST1 PF15013.6 KDO20291.1 - 9.3 6.5 5.6 13 6.0 0.6 2.1 2 0 0 2 2 2 0 CCSMST1 family LRR_6 PF13516.6 KDO20292.1 - 1.9e-05 24.3 0.8 0.2 11.8 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KDO20292.1 - 0.046 14.2 0.4 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF5131 PF07505.11 KDO20292.1 - 0.078 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) GST_N_2 PF13409.6 KDO20294.1 - 1.8e-22 79.4 0.0 4.8e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO20294.1 - 9.1e-13 48.0 0.0 6.4e-12 45.3 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO20294.1 - 7.2e-09 35.7 0.0 2.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO20294.1 - 4.8e-07 29.9 0.0 9.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KDO20294.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO20294.1 - 0.0044 17.4 0.0 0.19 12.2 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4570 PF15134.6 KDO20295.1 - 0.14 12.2 6.7 0.27 11.3 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) PMSR PF01625.21 KDO20296.1 - 1.1e-61 207.5 0.2 1.4e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UspA1_rep PF18792.1 KDO20296.1 - 0.0051 17.2 1.1 0.01 16.2 1.1 1.6 1 0 0 1 1 1 1 Ubiquitous surface protein adhesin repeat PMSR PF01625.21 KDO20297.1 - 3.3e-60 202.7 3.5 3.9e-60 202.5 3.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PFO_beta_C PF12367.8 KDO20297.1 - 0.0063 16.6 1.5 2.8 8.1 0.2 2.5 1 1 1 2 2 2 2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal ABC_membrane PF00664.23 KDO20299.1 - 2.8e-52 178.1 25.2 2.3e-27 96.4 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO20299.1 - 1.5e-44 151.8 0.0 7.7e-25 88.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO20299.1 - 8e-07 28.7 0.0 0.0035 16.8 0.4 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO20299.1 - 0.0001 22.8 0.1 0.28 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO20299.1 - 0.00022 21.2 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO20299.1 - 0.00095 19.2 1.2 0.044 13.9 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO20299.1 - 0.037 14.3 0.5 13 6.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KDO20299.1 - 0.042 13.7 0.1 5.6 6.7 0.3 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO20299.1 - 0.085 12.6 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribonuc_red_sm PF00268.21 KDO20300.1 - 1.2e-114 382.5 1.4 1.4e-114 382.3 1.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 KDO20300.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain PX PF00787.24 KDO20301.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Atg8 PF02991.16 KDO20302.1 - 1.3e-51 173.1 0.1 1.5e-51 172.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KDO20302.1 - 2.7e-07 30.9 0.0 3.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 WD40 PF00400.32 KDO20303.1 - 6.4e-22 77.4 40.7 0.003 18.4 0.1 11.3 10 2 1 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20303.1 - 4.1e-09 36.6 4.0 0.75 10.1 0.0 7.4 5 2 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO20303.1 - 0.032 12.9 0.8 0.074 11.7 0.3 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KDO20303.1 - 0.23 11.4 1.4 53 3.9 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ABC_membrane PF00664.23 KDO20304.1 - 3.3e-54 184.4 29.7 2e-29 103.1 12.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO20304.1 - 1.4e-17 64.5 0.0 6.2e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KDO20304.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain IlvC PF01450.19 KDO20305.1 - 7.9e-41 139.7 0.0 7.9e-31 107.3 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 KDO20305.1 - 8.2e-35 119.8 0.0 1.5e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KDO20305.1 - 0.052 14.1 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FIST PF08495.10 KDO20306.1 - 0.0034 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 FIST N domain SNF2_N PF00176.23 KDO20307.1 - 1.3e-60 205.0 1.8 2.2e-60 204.2 1.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO20307.1 - 1.1e-20 74.1 0.0 2.4e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KDO20307.1 - 1.6e-17 63.4 0.0 4.1e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KDO20307.1 - 2e-12 46.8 4.1 4.6e-12 45.6 4.1 1.7 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.24 KDO20307.1 - 4.8e-12 45.6 0.3 4.3e-06 26.5 0.0 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KDO20307.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PDZ PF00595.24 KDO20307.1 - 4.5e-05 23.7 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain HDA2-3 PF11496.8 KDO20307.1 - 9.2e-05 21.7 0.1 0.00029 20.1 0.1 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PDZ_6 PF17820.1 KDO20307.1 - 0.00061 19.6 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SWI2_SNF2 PF18766.1 KDO20307.1 - 0.0016 18.2 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 KDO20307.1 - 0.0029 17.4 0.0 0.0074 16.1 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase PHD_2 PF13831.6 KDO20307.1 - 0.0064 16.0 0.2 0.013 15.0 0.2 1.6 1 0 0 1 1 1 1 PHD-finger ERCC3_RAD25_C PF16203.5 KDO20307.1 - 0.0094 15.2 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase USP19_linker PF16602.5 KDO20307.1 - 0.096 13.2 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase BUD22 PF09073.10 KDO20307.1 - 1.1 8.5 10.3 0.26 10.6 5.5 2.1 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 KDO20307.1 - 1.6 8.0 12.0 3.7 6.9 12.0 1.5 1 0 0 1 1 1 0 SDA1 Prok-RING_1 PF14446.6 KDO20307.1 - 2.4 8.2 6.6 3.5 7.6 3.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRN3 PF05327.11 KDO20307.1 - 8.8 4.7 7.7 19 3.7 7.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PHD PF00628.29 KDO20308.1 - 1.3e-15 57.0 30.6 5.2e-09 35.9 2.9 3.4 3 0 0 3 3 3 3 PHD-finger PHD_2 PF13831.6 KDO20308.1 - 4.5e-06 26.1 7.0 2.9e-05 23.5 0.8 3.5 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.6 KDO20308.1 - 0.00037 20.7 32.5 0.18 12.1 0.1 3.4 2 1 1 3 3 3 3 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KDO20308.1 - 0.038 14.3 32.7 0.92 9.9 5.7 3.6 3 0 0 3 3 3 0 Ring finger domain TPR_19 PF14559.6 KDO20309.1 - 5.6e-35 119.7 38.2 5.3e-08 33.3 1.4 10.8 6 4 5 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20309.1 - 2.2e-34 114.8 38.2 0.00023 21.0 0.5 15.0 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20309.1 - 3.2e-33 112.2 35.6 2.6e-05 23.8 0.1 14.4 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20309.1 - 9.5e-30 100.7 35.1 0.00031 21.3 0.2 12.6 7 4 6 13 13 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20309.1 - 3.4e-27 94.8 33.0 4.1e-08 33.8 0.1 10.1 8 3 2 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20309.1 - 3.1e-25 88.3 34.0 1.5e-06 28.4 0.5 10.2 5 4 5 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20309.1 - 4e-25 86.0 19.6 0.00034 20.4 0.0 11.4 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20309.1 - 2.2e-23 80.5 31.7 0.0011 19.0 0.0 14.3 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20309.1 - 2.3e-15 55.9 30.2 0.0053 16.6 0.4 11.4 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20309.1 - 7.4e-15 54.4 32.4 0.09 12.5 1.2 12.4 10 3 4 14 14 14 6 TPR repeat TPR_6 PF13174.6 KDO20309.1 - 1.2e-14 53.9 39.1 0.014 16.0 0.8 13.4 15 0 0 15 15 13 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO20309.1 - 1.7e-13 50.6 22.6 0.0004 20.5 2.7 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KDO20309.1 - 9.2e-11 41.4 25.1 1.3 9.6 0.0 12.2 13 1 1 14 14 12 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO20309.1 - 3.1e-10 40.0 26.2 0.017 15.3 1.0 8.3 6 2 1 8 8 8 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KDO20309.1 - 4.1e-08 32.9 2.0 0.0045 16.6 0.3 4.0 3 0 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KDO20309.1 - 1.3e-06 28.5 6.6 0.29 11.9 0.9 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat YfiO PF13525.6 KDO20309.1 - 1.1e-05 25.2 13.4 0.065 12.9 0.4 3.8 3 0 0 3 3 3 3 Outer membrane lipoprotein TPR_20 PF14561.6 KDO20309.1 - 1.6e-05 25.1 20.6 0.74 10.2 0.1 8.0 6 2 2 8 8 7 2 Tetratricopeptide repeat ChAPs PF09295.10 KDO20309.1 - 0.0016 17.5 0.2 0.24 10.4 0.0 2.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4919 PF16266.5 KDO20309.1 - 0.28 11.1 3.7 2.8 7.9 0.2 3.7 4 1 1 5 5 4 0 Domain of unknown function (DUF4919) Fis1_TPR_C PF14853.6 KDO20309.1 - 6.3 6.9 18.6 2.8 8.1 0.0 6.3 7 2 2 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat Mlo PF03094.15 KDO20310.1 - 0.00023 19.7 2.0 0.00023 19.7 2.0 3.5 2 1 1 4 4 4 2 Mlo family DUF4381 PF14316.6 KDO20310.1 - 0.1 12.9 0.4 0.1 12.9 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) BatA PF07584.11 KDO20310.1 - 0.44 10.9 0.1 0.44 10.9 0.1 3.3 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal TMEM132D_C PF15706.5 KDO20310.1 - 0.6 9.9 3.2 11 5.8 0.1 3.3 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4577 PF15145.6 KDO20310.1 - 5.2 7.1 5.7 2.3 8.3 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4577) DUF948 PF06103.11 KDO20310.1 - 5.9 7.2 14.4 16 5.8 0.0 4.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Moricin PF06451.11 KDO20311.1 - 0.013 15.3 0.1 0.045 13.5 0.1 1.9 1 0 0 1 1 1 0 Moricin Tombus_P33 PF08500.10 KDO20311.1 - 0.028 14.4 0.1 0.039 13.9 0.1 1.2 1 0 0 1 1 1 0 Tombusvirus p33 FAIM1 PF06905.13 KDO20312.1 - 6.9e-08 32.4 0.1 9.9e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) zf-RanBP PF00641.18 KDO20312.1 - 2.3e-05 23.6 1.9 2.3e-05 23.6 1.9 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others CBM_35 PF16990.5 KDO20312.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) Vps36-NZF-N PF16988.5 KDO20312.1 - 0.45 10.0 3.1 2.2 7.8 3.1 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ank_2 PF12796.7 KDO20313.1 - 5.4e-18 65.4 19.2 3.3e-07 30.8 0.2 3.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20313.1 - 4.1e-15 55.9 11.4 0.00029 21.4 0.0 5.7 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20313.1 - 2.9e-11 43.4 12.2 0.026 14.9 0.1 7.2 1 1 6 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20313.1 - 1.9e-10 40.0 7.3 0.5 11.1 0.0 8.1 5 3 3 8 8 8 2 Ankyrin repeat Ank PF00023.30 KDO20313.1 - 0.07 13.6 11.1 11 6.7 0.0 6.4 1 1 3 4 4 4 0 Ankyrin repeat Glyco_transf_4 PF13439.6 KDO20313.1 - 3.8 7.5 10.5 0.3 11.1 0.8 2.8 1 1 1 2 2 2 0 Glycosyltransferase Family 4 Glyco_hydro81C PF17652.1 KDO20314.1 - 2.2e-81 273.8 3.7 3.4e-81 273.2 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KDO20314.1 - 6.6e-30 104.4 0.1 1.2e-29 103.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain rRNA_proc-arch PF13234.6 KDO20315.1 - 4.2e-68 230.2 0.0 7.4e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KDO20315.1 - 3.3e-50 169.9 0.5 8.3e-50 168.7 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KDO20315.1 - 4.5e-19 68.9 0.0 2.6e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO20315.1 - 6.8e-07 29.6 0.0 7.9e-06 26.2 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 KDO20315.1 - 0.16 11.8 0.2 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SPX PF03105.19 KDO20316.1 - 3.7e-25 89.7 18.9 1.1e-13 51.8 1.1 3.0 1 1 2 3 3 3 3 SPX domain TyeA PF09059.10 KDO20316.1 - 0.074 13.2 1.8 24 5.1 0.0 3.3 2 2 1 3 3 3 0 TyeA DUF4298 PF14131.6 KDO20316.1 - 0.81 9.7 3.7 2 8.4 1.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) His_Phos_2 PF00328.22 KDO20317.1 - 1.4e-17 64.2 0.0 4.5e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) FYVE PF01363.21 KDO20322.1 - 1.1e-20 73.5 46.1 1e-07 32.0 10.5 3.4 1 1 2 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.16 KDO20322.1 - 1.9e-06 28.1 42.7 0.00038 20.6 2.2 3.9 2 1 1 3 3 3 3 FYVE-type zinc finger C1_2 PF03107.16 KDO20322.1 - 0.012 15.9 6.9 0.012 15.9 6.9 5.2 4 2 0 4 4 4 0 C1 domain ANF_receptor PF01094.28 KDO20323.1 - 2.7e-08 33.3 2.3 7.8e-08 31.8 2.3 1.8 1 1 0 1 1 1 1 Receptor family ligand binding region Lzipper-MIP1 PF14389.6 KDO20324.1 - 0.00086 19.6 2.7 0.00088 19.5 0.8 1.8 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 SPECT1 PF18680.1 KDO20324.1 - 0.15 11.7 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 DUF4404 PF14357.6 KDO20324.1 - 0.39 11.4 3.1 20 5.9 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Trypsin_2 PF13365.6 KDO20325.1 - 2.6e-14 54.4 4.1 5.4e-10 40.4 0.3 3.3 2 1 1 3 3 3 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KDO20325.1 - 1.7e-05 25.0 0.0 0.38 11.1 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KDO20325.1 - 1.8e-05 24.5 0.3 0.093 12.6 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_1 PF12812.7 KDO20325.1 - 3.8e-05 23.6 0.0 9.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 PDZ-like domain Sec8_exocyst PF04048.14 KDO20326.1 - 2.7e-11 43.5 0.1 5.4e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KDO20326.1 - 0.00024 20.5 0.1 0.00046 19.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KDO20326.1 - 0.0068 16.2 0.0 0.028 14.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 KDO20326.1 - 0.061 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DDR_swiveling PF18427.1 KDO20326.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain RE_TdeIII PF09520.10 KDO20326.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII PT PF04886.12 KDO20327.1 - 0.084 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 PT repeat CTP_transf_3 PF02348.19 KDO20328.1 - 7.1e-39 134.0 0.0 8.7e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 KDO20328.1 - 2.5e-08 34.5 0.5 4.1e-08 33.7 0.5 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KDO20328.1 - 0.0009 19.0 0.2 0.025 14.3 0.1 2.0 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SNF2_N PF00176.23 KDO20330.1 - 6.1e-58 196.2 0.4 1.1e-57 195.3 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO20330.1 - 3.4e-17 62.8 0.0 1.2e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 KDO20330.1 - 2e-16 59.6 1.7 2.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KDO20330.1 - 5.4e-08 33.0 0.0 1.3e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HAGH_C PF16123.5 KDO20332.1 - 3.6e-26 91.5 0.0 1e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KDO20332.1 - 2.4e-10 40.7 0.7 4.8e-10 39.8 0.7 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO20332.1 - 0.00015 21.3 0.0 0.00071 19.2 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KDO20332.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CEP19 PF14933.6 KDO20333.1 - 1.3e-23 84.1 0.0 1.3e-16 61.3 0.0 2.0 1 1 1 2 2 2 2 CEP19-like protein PH PF00169.29 KDO20334.1 - 1.7e-11 44.6 0.0 3.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Phage_GP20 PF06810.11 KDO20334.1 - 0.087 12.6 0.7 0.31 10.8 0.7 2.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 Mei5 PF10376.9 KDO20334.1 - 0.19 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein DIX PF00778.17 KDO20335.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 DIX domain Pkinase PF00069.25 KDO20336.1 - 6.5e-51 173.2 0.0 9.4e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20336.1 - 1e-36 126.6 0.0 1.6e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO20336.1 - 0.018 13.8 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase SSFA2_C PF14723.6 KDO20336.1 - 0.053 13.4 0.2 0.16 11.9 0.2 1.8 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Galactosyl_T PF01762.21 KDO20337.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase MOSC_N PF03476.16 KDO20338.1 - 0.0034 17.3 1.0 0.3 11.0 0.0 2.6 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain His_Phos_2 PF00328.22 KDO20338.1 - 0.005 16.2 3.2 0.0075 15.7 3.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF16 PF01519.16 KDO20338.1 - 0.0067 16.9 4.6 0.0067 16.9 4.6 2.4 2 0 0 2 2 2 1 Protein of unknown function DUF16 DUF725 PF05267.12 KDO20338.1 - 0.011 15.7 2.4 0.021 14.8 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF3145 PF11343.8 KDO20338.1 - 0.02 14.4 0.4 0.049 13.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Fez1 PF06818.15 KDO20338.1 - 0.033 14.7 22.8 0.027 14.9 5.5 3.0 1 1 2 3 3 3 0 Fez1 DUF2408 PF10303.9 KDO20338.1 - 0.038 14.5 14.0 0.64 10.6 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) bZIP_Maf PF03131.17 KDO20338.1 - 0.11 13.0 19.0 0.075 13.6 3.7 4.0 2 2 2 4 4 4 0 bZIP Maf transcription factor JIP_LZII PF16471.5 KDO20338.1 - 0.23 11.6 17.5 1.8 8.8 5.4 3.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Fzo_mitofusin PF04799.13 KDO20338.1 - 0.59 9.7 16.2 0.6 9.6 0.5 3.4 2 1 2 4 4 4 0 fzo-like conserved region Cob_adeno_trans PF01923.18 KDO20338.1 - 0.66 10.1 13.1 0.17 12.0 4.9 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TEX13 PF15186.6 KDO20338.1 - 0.99 9.1 25.3 0.41 10.3 5.0 3.2 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family Cep57_CLD PF14073.6 KDO20338.1 - 1.2 9.1 23.4 0.41 10.6 12.3 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF2937 PF11157.8 KDO20338.1 - 1.3 8.7 8.8 0.071 12.8 2.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) Plk4_PB2 PF18409.1 KDO20338.1 - 1.6 9.5 4.7 2.2 9.0 0.6 2.8 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 BLOC1_2 PF10046.9 KDO20338.1 - 2.5 8.5 13.2 1.7 9.0 5.5 3.4 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KDO20338.1 - 3.1 7.9 29.2 0.72 9.9 16.6 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KDO20338.1 - 4 7.7 27.3 0.81 9.9 4.6 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 KDO20338.1 - 4.7 7.4 33.0 13 5.9 18.9 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KDO20338.1 - 5.6 6.2 12.6 5 6.4 6.6 2.2 2 0 0 2 2 2 0 FAM76 protein HAUS-augmin3 PF14932.6 KDO20338.1 - 5.6 6.5 28.4 0.39 10.3 15.0 2.5 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc29 PF17082.5 KDO20338.1 - 5.9 6.6 12.7 3 7.6 7.7 2.7 1 1 0 2 2 2 0 Spindle Pole Component 29 TolA_bind_tri PF16331.5 KDO20338.1 - 6.1 7.0 26.5 1.2 9.3 5.1 4.7 3 2 1 4 4 4 0 TolA binding protein trimerisation UPF0242 PF06785.11 KDO20338.1 - 6.8 6.7 22.2 98 3.0 20.6 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 KDO20338.1 - 7.9 6.9 26.3 0.19 12.2 2.5 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 KDO20338.1 - 8.5 7.1 20.0 1.3 9.7 0.5 3.9 2 2 1 3 3 3 0 Initiation control protein YabA Glyco_hydro_72 PF03198.14 KDO20339.1 - 5.1e-37 127.8 6.8 7.1e-36 124.0 6.8 2.2 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KDO20339.1 - 0.0056 16.1 0.4 0.0097 15.4 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LRR_4 PF12799.7 KDO20340.1 - 1.9e-31 107.6 41.2 1.6e-08 34.7 0.5 6.9 1 1 8 10 10 10 9 Leucine Rich repeats (2 copies) PH PF00169.29 KDO20340.1 - 2.5e-20 72.9 0.0 2.2e-06 28.1 0.0 4.5 4 0 0 4 4 4 4 PH domain LRR_9 PF14580.6 KDO20340.1 - 3.4e-18 65.8 11.3 2.5e-10 40.1 0.8 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 KDO20340.1 - 5.9e-18 64.4 28.9 5.5e-06 26.0 1.5 5.6 1 1 3 5 5 5 5 Leucine rich repeat PH_2 PF08458.10 KDO20340.1 - 0.014 15.7 0.7 0.18 12.2 0.0 3.0 3 0 0 3 3 3 0 Plant pleckstrin homology-like region LRR_1 PF00560.33 KDO20340.1 - 0.015 15.8 18.6 16 6.5 0.2 8.4 8 2 0 8 8 8 0 Leucine Rich Repeat PH_13 PF16652.5 KDO20340.1 - 0.066 13.0 0.1 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.6 KDO20340.1 - 0.22 12.0 3.1 9.5 6.7 0.0 4.0 4 0 0 4 4 4 0 Pleckstrin homology domain LRR_6 PF13516.6 KDO20340.1 - 1.2 9.4 19.7 5.1 7.4 0.0 8.0 9 0 0 9 9 9 0 Leucine Rich repeat PUB PF09409.10 KDO20342.1 - 0.0025 17.7 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 PUB domain Amidase02_C PF12123.8 KDO20342.1 - 0.025 14.3 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase TPH PF13868.6 KDO20343.1 - 1.5e-17 63.1 109.7 1.5e-17 63.1 109.7 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain IQ PF00612.27 KDO20344.1 - 1.3e-14 52.6 42.4 0.00065 19.3 0.0 8.0 7 0 0 7 7 7 7 IQ calmodulin-binding motif WW PF00397.26 KDO20344.1 - 2.1e-14 53.3 9.7 9.4e-09 35.2 4.4 2.5 2 0 0 2 2 2 2 WW domain zf-B_box PF00643.24 KDO20344.1 - 5.3e-06 26.5 13.9 0.0098 16.0 4.0 2.4 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 KDO20344.1 - 0.0015 18.7 15.5 0.2 11.9 3.9 2.6 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF4778 PF16008.5 KDO20344.1 - 3.6 7.6 8.3 7.6 6.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4778) IBR PF01485.21 KDO20344.1 - 5.1 7.4 12.9 1.3 9.3 1.0 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PX PF00787.24 KDO20345.1 - 4.7e-16 58.8 0.0 1.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Peptidase_C92 PF05708.12 KDO20345.1 - 9.7e-06 25.8 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PH PF00169.29 KDO20345.1 - 0.013 16.0 0.0 0.15 12.6 0.0 2.6 2 1 0 2 2 2 0 PH domain Pkinase PF00069.25 KDO20346.1 - 1.5e-63 214.7 0.0 7.6e-63 212.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20346.1 - 2.7e-31 108.8 0.0 7.4e-25 87.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase PAS PF00989.25 KDO20346.1 - 2.3e-07 30.8 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KDO20346.1 - 0.00013 22.1 0.0 0.00032 20.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KDO20346.1 - 0.00079 19.7 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold APH PF01636.23 KDO20346.1 - 0.0018 18.2 0.9 0.0027 17.6 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO20346.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.7 KDO20346.1 - 0.015 15.3 0.0 0.067 13.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain UvsY PF11056.8 KDO20351.1 - 0.041 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF1016_N PF17761.1 KDO20351.1 - 0.066 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain DUF1016_N PF17761.1 KDO20352.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 DUF1016 N-terminal domain Mannosyl_trans3 PF11051.8 KDO20354.1 - 0.00053 19.4 0.1 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KDO20354.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ank_4 PF13637.6 KDO20355.1 - 2.9e-15 56.4 0.1 2.4e-06 28.0 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO20355.1 - 1.1e-13 50.9 0.0 7.1e-07 29.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO20355.1 - 1.5e-11 43.4 0.3 0.0057 17.1 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KDO20355.1 - 1.7e-11 44.5 0.0 2.3e-10 40.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20355.1 - 7.8e-11 42.0 0.1 1e-05 25.7 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Trp_repressor PF01371.19 KDO20359.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Trp repressor protein PRMT5_TIM PF17285.2 KDO20359.1 - 0.1 11.8 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 PRMT5 TIM barrel domain p25-alpha PF05517.12 KDO20359.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 p25-alpha DUF2373 PF10180.9 KDO20362.1 - 4.3e-18 64.9 0.2 7.4e-18 64.1 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF4874 PF16173.5 KDO20362.1 - 0.071 12.8 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Pkinase_Tyr PF07714.17 KDO20365.1 - 3.7e-16 59.2 0.0 4.8e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20365.1 - 8.5e-10 38.4 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Crystall PF00030.19 KDO20365.1 - 7e-07 29.4 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KDO20365.1 - 0.029 14.3 0.1 1.5 8.8 0.0 3.0 3 1 0 3 3 3 0 Peptidase inhibitor family I36 RskA PF10099.9 KDO20365.1 - 0.037 14.3 0.2 0.037 14.3 0.2 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SecE PF00584.20 KDO20365.1 - 9.4 6.3 8.9 1 9.4 0.2 2.3 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Elicitin PF00964.17 KDO20366.1 - 3e-06 27.2 2.5 0.061 13.4 0.0 2.4 2 0 0 2 2 2 2 Elicitin Elicitin PF00964.17 KDO20367.1 - 8.9e-05 22.5 1.8 0.19 11.8 0.1 2.7 2 1 0 2 2 2 2 Elicitin LRR_4 PF12799.7 KDO20369.1 - 0.0003 21.1 9.4 0.066 13.7 0.6 4.1 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO20369.1 - 0.0029 17.5 14.7 15 6.0 0.0 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KDO20369.1 - 0.0054 17.1 11.0 9.4 7.2 0.0 6.6 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 KDO20369.1 - 0.6 9.9 17.5 9.2 6.1 0.9 5.5 5 1 1 6 6 6 0 Leucine rich repeat PAN_4 PF14295.6 KDO20370.1 - 2.9e-56 187.2 77.5 1.7e-08 34.2 3.4 10.9 9 1 1 10 10 10 8 PAN domain 3-dmu-9_3-mt PF06983.13 KDO20370.1 - 2.8e-09 37.5 11.1 0.44 11.1 0.1 6.4 7 0 0 7 7 7 4 3-demethylubiquinone-9 3-methyltransferase MCRA PF06100.11 KDO20370.1 - 0.045 12.5 0.2 17 4.1 0.0 3.0 3 0 0 3 3 3 0 MCRA family OCD_Mu_crystall PF02423.15 KDO20370.1 - 0.097 11.6 0.1 7.5 5.4 0.1 2.9 3 0 0 3 3 3 0 Ornithine cyclodeaminase/mu-crystallin family Whib PF02467.16 KDO20370.1 - 2.4 8.8 35.6 11 6.7 0.6 7.2 7 0 0 7 7 7 0 Transcription factor WhiB MAR_sialic_bdg PF10564.9 KDO20370.1 - 2.7 8.1 51.3 0.94 9.6 0.9 7.3 7 0 0 7 7 7 0 Sialic-acid binding micronemal adhesive repeat eIF2_C PF09173.11 KDO20372.1 - 3.2e-13 49.8 0.1 4.9e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 KDO20372.1 - 0.0011 19.3 0.1 0.0025 18.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ProQ_C PF17516.2 KDO20372.1 - 0.02 14.3 0.2 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain LRR_8 PF13855.6 KDO20373.1 - 5.8e-16 58.0 4.6 1.2e-09 37.8 0.4 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO20373.1 - 8.9e-11 41.9 0.5 0.00014 22.2 0.1 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO20373.1 - 3.8e-07 29.7 0.1 2.3 9.1 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRRNT_2 PF08263.12 KDO20373.1 - 0.023 15.0 4.9 0.061 13.6 4.9 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KDO20373.1 - 0.042 13.9 1.1 6.8 7.0 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat YtpI PF14007.6 KDO20375.1 - 0.021 14.9 0.8 0.078 13.1 0.1 2.3 2 0 0 2 2 2 0 YtpI-like protein WHIM1 PF15612.6 KDO20377.1 - 0.15 11.6 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Chordopox_L2 PF05803.12 KDO20377.1 - 0.35 10.7 4.0 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Ank_2 PF12796.7 KDO20378.1 - 2e-11 44.3 2.9 7.7e-08 32.8 1.8 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20378.1 - 1.7e-09 38.0 4.8 0.0043 17.6 0.3 5.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20378.1 - 1e-07 31.7 1.6 2.3 9.0 0.0 5.5 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KDO20378.1 - 1.4e-05 25.3 8.0 0.24 11.8 0.1 5.3 3 1 3 6 6 6 3 Ankyrin repeats (many copies) PHD PF00628.29 KDO20379.1 - 0.0001 22.1 20.4 0.036 13.9 10.7 3.1 2 1 0 2 2 2 2 PHD-finger FAM176 PF14851.6 KDO20379.1 - 0.74 9.5 5.6 2.3 7.8 1.0 2.3 2 0 0 2 2 2 0 FAM176 family zf-RING_9 PF13901.6 KDO20379.1 - 2.3 8.1 9.2 9.5 6.1 8.2 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon BUD22 PF09073.10 KDO20379.1 - 2.5 7.4 8.5 8.5 5.6 4.5 2.0 2 0 0 2 2 2 0 BUD22 Zn_ribbon_SprT PF17283.2 KDO20379.1 - 3.9 7.4 9.7 2.5 8.1 0.1 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DZR PF12773.7 KDO20379.1 - 5.5 7.1 16.9 6.9 6.8 0.8 3.4 1 1 1 2 2 2 0 Double zinc ribbon LRR_6 PF13516.6 KDO20380.1 - 1.8e-07 30.6 10.7 0.034 14.2 0.0 6.6 8 0 0 8 8 8 4 Leucine Rich repeat BT1 PF03092.16 KDO20381.1 - 1.5e-10 39.9 2.6 1.5e-10 39.9 2.6 2.4 2 1 0 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO20381.1 - 4.5e-07 29.1 38.8 0.0034 16.4 3.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 KDO20381.1 - 1.5 8.9 7.6 1.2 9.2 3.2 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S PI3Ka PF00613.20 KDO20382.1 - 0.023 14.1 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ABC_tran PF00005.27 KDO20384.1 - 3.6e-29 102.0 0.0 5.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO20384.1 - 2.1e-23 83.4 7.1 3.4e-23 82.7 7.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO20384.1 - 4.9e-08 32.7 0.0 0.00048 19.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO20384.1 - 8.9e-06 25.7 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO20384.1 - 9e-05 22.9 0.0 0.00025 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO20384.1 - 0.00038 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO20384.1 - 0.00082 19.7 1.8 0.017 15.4 0.6 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO20384.1 - 0.0014 18.2 0.0 0.062 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KDO20384.1 - 0.0016 19.0 0.0 0.0028 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KDO20384.1 - 0.0035 17.3 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KDO20384.1 - 0.0097 15.6 0.0 0.037 13.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_membrane_2 PF06472.15 KDO20384.1 - 0.024 14.0 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 NACHT PF05729.12 KDO20384.1 - 0.043 13.7 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 KDO20384.1 - 0.054 13.2 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KDO20384.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KDO20384.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KDO20384.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Peptidase_C1 PF00112.23 KDO20386.1 - 2.1e-58 198.0 13.7 2.1e-58 198.0 13.7 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20386.1 - 0.00034 19.5 1.9 0.072 11.8 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KDO20386.1 - 0.12 12.8 0.5 0.3 11.6 0.5 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) PT PF04886.12 KDO20386.1 - 0.26 10.9 9.4 0.55 9.8 9.4 1.4 1 0 0 1 1 1 0 PT repeat Peptidase_C1 PF00112.23 KDO20387.1 - 3e-49 168.1 13.3 3.4e-48 164.6 13.3 2.0 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20387.1 - 0.0015 17.4 1.3 0.23 10.2 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PT PF04886.12 KDO20387.1 - 0.028 14.0 5.4 0.055 13.0 5.4 1.4 1 0 0 1 1 1 0 PT repeat SF1-HH PF16275.5 KDO20388.1 - 1.8e-25 89.5 1.1 1.8e-25 89.5 1.1 2.0 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KDO20388.1 - 1.8e-08 34.1 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 KH domain PHD_4 PF16866.5 KDO20388.1 - 5e-05 23.3 2.4 9.6e-05 22.4 2.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-CCHC PF00098.23 KDO20388.1 - 0.031 14.4 2.0 0.031 14.4 2.0 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 KDO20388.1 - 0.21 11.6 4.7 3.2 7.8 4.7 2.6 1 1 0 1 1 1 0 Zinc knuckle Peptidase_C1 PF00112.23 KDO20389.1 - 1.4e-60 205.1 12.3 2.9e-60 204.1 12.3 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20389.1 - 2.4e-06 26.6 2.4 0.0031 16.4 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KDO20389.1 - 0.093 13.2 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) BT1 PF03092.16 KDO20390.1 - 1.2e-14 53.5 10.2 2.2e-13 49.3 1.4 2.4 2 0 0 2 2 2 2 BT1 family HTH_23 PF13384.6 KDO20391.1 - 7.4e-05 22.4 0.4 0.00058 19.6 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KDO20391.1 - 0.00067 19.4 0.9 0.002 17.9 0.9 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KDO20391.1 - 0.00081 19.3 0.6 0.026 14.5 0.1 2.7 3 0 0 3 3 3 1 HTH domain TrmB PF01978.19 KDO20391.1 - 0.0041 17.0 0.2 2.9 7.8 0.0 2.6 2 1 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 KDO20391.1 - 0.014 15.5 0.3 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain LytR_C PF13399.6 KDO20391.1 - 0.031 15.2 0.5 0.3 12.1 0.2 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator BT1 PF03092.16 KDO20392.1 - 2e-17 62.6 12.9 1.8e-15 56.2 2.5 2.4 2 0 0 2 2 2 2 BT1 family Peptidase_C1 PF00112.23 KDO20394.1 - 9.2e-31 107.6 5.8 1.3e-30 107.2 5.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KDO20394.1 - 0.14 12.6 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Pkinase PF00069.25 KDO20396.1 - 7.7e-53 179.5 0.0 9.7e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20396.1 - 3.7e-51 173.9 0.0 4.5e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO20396.1 - 0.00094 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO20396.1 - 0.0071 16.3 0.1 0.016 15.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO20396.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4444 PF14563.6 KDO20396.1 - 0.019 14.6 0.7 0.042 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) FTA2 PF13095.6 KDO20396.1 - 0.025 14.2 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KDO20396.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C1 PF00112.23 KDO20398.1 - 3.5e-51 174.4 4.7 4.6e-51 174.0 4.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20398.1 - 0.0011 17.8 0.5 0.084 11.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family SlpA PF03217.14 KDO20398.1 - 0.4 11.3 1.9 0.9 10.2 0.3 2.2 2 0 0 2 2 2 0 Surface later protein A domain Ank_4 PF13637.6 KDO20399.1 - 0.039 14.5 0.1 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20399.1 - 0.049 14.2 0.2 0.19 12.3 0.1 2.0 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) FIBP PF05427.11 KDO20400.1 - 1.1e-09 38.1 0.1 1.8e-09 37.4 0.1 1.3 1 1 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Ank_2 PF12796.7 KDO20402.1 - 2.1e-60 201.2 10.4 2.6e-09 37.5 0.1 7.3 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20402.1 - 8.3e-49 163.4 14.4 2.5e-08 34.3 0.0 11.3 6 4 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20402.1 - 1.4e-45 152.7 23.9 2.3e-07 30.9 0.2 12.0 5 3 7 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20402.1 - 2.9e-41 134.7 19.3 0.0029 18.0 0.0 15.6 15 1 1 16 16 16 9 Ankyrin repeat Ank PF00023.30 KDO20402.1 - 2.8e-25 87.6 42.0 0.049 14.1 0.3 13.8 12 4 2 14 14 14 8 Ankyrin repeat Sec61_beta PF03911.16 KDO20402.1 - 5.6e-19 67.9 0.1 1.4e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 Sec61beta family Spt4 PF06093.13 KDO20403.1 - 1.1e-33 115.1 0.7 1.4e-33 114.8 0.7 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger SF3b10 PF07189.11 KDO20404.1 - 2.9e-40 136.2 0.0 3.3e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) EF-hand_8 PF13833.6 KDO20405.1 - 4e-11 42.6 0.1 1.3e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO20405.1 - 0.00016 22.0 3.2 0.14 12.6 0.8 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO20405.1 - 0.0015 17.9 1.2 0.0045 16.5 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO20405.1 - 0.015 15.2 1.5 9 6.5 0.1 3.6 4 0 0 4 4 4 0 EF-hand domain HrpB2 PF09487.10 KDO20405.1 - 0.089 13.2 1.1 16 6.0 0.4 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB2) His_biosynth PF00977.21 KDO20406.1 - 3.6e-30 105.1 0.1 5e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KDO20406.1 - 0.071 12.5 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family tRNA-synt_1e PF01406.19 KDO20407.1 - 8.8e-119 396.3 0.0 1.4e-118 395.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KDO20407.1 - 6.2e-08 33.0 2.2 1.4e-07 31.9 0.0 2.6 2 0 0 2 2 2 1 DALR domain tRNA-synt_1g PF09334.11 KDO20407.1 - 1.8e-05 23.7 0.5 5.8e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (M) DUF1978 PF09321.10 KDO20407.1 - 0.0074 15.6 0.0 0.0074 15.6 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1978) tRNA-synt_1c PF00749.21 KDO20407.1 - 0.031 13.2 0.0 0.031 13.2 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 KDO20407.1 - 0.08 11.8 0.1 0.43 9.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) Remorin_C PF03763.13 KDO20407.1 - 2.2 8.2 12.8 0.2 11.5 6.9 2.3 2 0 0 2 2 2 0 Remorin, C-terminal region S4 PF01479.25 KDO20408.1 - 6e-09 35.5 1.8 7.6e-09 35.2 0.3 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KDO20408.1 - 4.2e-06 27.6 2.1 1.4e-05 25.9 2.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain KH_6 PF15985.5 KDO20410.1 - 1.7e-12 47.5 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 KH domain SET PF00856.28 KDO20410.1 - 4e-06 27.3 0.0 3.1e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 SET domain Rrp40_N PF18311.1 KDO20410.1 - 0.00099 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Ribosomal_S17 PF00366.20 KDO20411.1 - 2.2e-30 104.5 1.9 2.5e-30 104.4 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ubiquitin_2 PF14560.6 KDO20412.1 - 1e-25 90.0 0.0 1.9e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KDO20412.1 - 2.8e-18 65.7 2.8 5.8e-18 64.7 2.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 KDO20412.1 - 0.00021 21.0 0.0 0.00065 19.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family SH3_12 PF18129.1 KDO20412.1 - 0.061 13.4 0.6 3.6 7.8 0.0 2.5 1 1 1 2 2 2 0 Xrn1 SH3-like domain DUF2964 PF11177.8 KDO20413.1 - 0.38 11.0 3.5 0.78 10.0 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2964) NUDIX PF00293.28 KDO20414.1 - 6.7e-17 61.8 0.1 9.3e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Mito_carr PF00153.27 KDO20415.1 - 1.2e-05 25.1 1.1 2.3e-05 24.2 0.4 1.8 2 1 0 2 2 2 1 Mitochondrial carrier protein SART-1 PF03343.13 KDO20416.1 - 2.3e-88 297.4 52.6 1.2e-70 238.8 36.2 3.1 2 1 1 3 3 3 2 SART-1 family Pkinase PF00069.25 KDO20417.1 - 2e-63 214.3 0.0 7.7e-63 212.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20417.1 - 6.9e-42 143.5 0.0 1.1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO20417.1 - 4.5e-07 29.5 0.0 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO20417.1 - 1.1e-05 24.5 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO20417.1 - 0.0017 18.3 0.1 1.5 8.7 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO20417.1 - 0.091 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bax1-I PF01027.20 KDO20418.1 - 0.0018 18.2 33.6 0.0026 17.6 33.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2339 PF10101.9 KDO20418.1 - 0.23 10.0 24.8 0.4 9.2 24.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF2254 PF10011.9 KDO20418.1 - 8.7 5.1 8.3 16 4.2 8.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Clathrin PF00637.20 KDO20419.1 - 1.6e-14 54.0 3.7 2.9e-13 49.9 0.6 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KDO20419.1 - 0.0011 19.3 1.0 0.0041 17.6 1.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_15 PF13429.6 KDO20419.1 - 0.0021 17.3 0.4 0.066 12.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 KDO20419.1 - 0.027 14.8 2.4 0.09 13.1 2.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40 PF00400.32 KDO20419.1 - 0.039 14.8 0.9 0.42 11.6 0.9 2.8 1 1 0 1 1 1 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20419.1 - 0.088 13.1 0.0 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 KDO20419.1 - 0.098 12.6 4.3 0.25 11.4 4.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KDO20419.1 - 0.47 10.2 4.2 1.4 8.8 4.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 KDO20419.1 - 0.64 10.4 9.1 0.12 12.7 4.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 KDO20419.1 - 2.1 8.4 4.3 5 7.2 4.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KDO20419.1 - 2.3 7.9 5.1 1.6 8.4 2.9 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TCTP PF00838.17 KDO20420.1 - 1.8e-41 142.2 1.6 2.1e-41 142.1 1.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF2232 PF09991.9 KDO20420.1 - 0.016 14.4 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) COPI_assoc PF08507.10 KDO20421.1 - 2e-15 57.0 7.0 2.5e-15 56.7 7.0 1.2 1 0 0 1 1 1 1 COPI associated protein COPI_assoc PF08507.10 KDO20422.1 - 1.3e-13 51.2 8.0 1.6e-13 50.8 8.0 1.1 1 0 0 1 1 1 1 COPI associated protein MHB PF16525.5 KDO20422.1 - 0.065 13.5 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Haemophore, haem-binding Fringe PF02434.16 KDO20423.1 - 2.3e-12 46.9 0.1 3.2e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KDO20423.1 - 0.0084 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Peptidase_C2 PF00648.21 KDO20424.1 - 3.2e-42 144.6 0.0 4.3e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KDO20424.1 - 1.3e-19 70.9 0.1 0.00018 21.8 0.0 5.0 4 1 0 4 4 4 3 Calpain large subunit, domain III Spc29 PF17082.5 KDO20425.1 - 8.4 6.2 8.6 3.7 7.3 0.7 2.3 2 0 0 2 2 2 0 Spindle Pole Component 29 zf-Tim10_DDP PF02953.15 KDO20426.1 - 2.6e-18 65.4 6.4 3.3e-18 65.1 6.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.20 KDO20426.1 - 0.0064 16.6 1.3 0.0071 16.4 1.3 1.1 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region Herpes_BLRF2 PF05812.12 KDO20426.1 - 0.02 15.0 0.3 0.021 14.9 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein CARD_2 PF16739.5 KDO20426.1 - 0.022 14.7 1.2 0.027 14.4 1.1 1.3 1 1 0 1 1 1 0 Caspase recruitment domain Vicilin_N PF04702.12 KDO20426.1 - 0.25 11.1 10.1 0.32 10.8 10.1 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Ribosomal_S21e PF01249.18 KDO20427.1 - 1.2e-36 124.6 0.1 1.5e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e G10 PF01125.17 KDO20428.1 - 3.6e-53 179.3 0.9 3.6e-53 179.3 0.9 1.5 2 0 0 2 2 2 1 G10 protein TLP-20 PF06088.11 KDO20428.1 - 0.017 15.0 1.4 0.024 14.5 1.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 KDO20428.1 - 0.53 8.5 10.8 0.64 8.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Myosin_head PF00063.21 KDO20429.1 - 6.2e-84 282.5 0.0 4.3e-50 170.7 0.0 3.4 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 KDO20429.1 - 1.5e-08 33.7 38.8 0.0043 16.7 0.4 7.4 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_16 PF13191.6 KDO20429.1 - 2.9e-05 24.5 0.1 2.9e-05 24.5 0.1 2.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KDO20429.1 - 0.022 15.0 0.1 0.1 12.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO20429.1 - 0.054 12.8 0.4 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KDO20429.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KDO20429.1 - 0.067 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 KDO20429.1 - 0.081 12.7 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 KDO20429.1 - 0.094 12.6 0.3 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 KDO20429.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RCC1 PF00415.18 KDO20430.1 - 3.5e-45 152.4 26.4 1.2e-15 57.8 0.3 7.6 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO20430.1 - 4.8e-29 99.5 42.9 4.7e-08 32.6 2.8 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KDO20430.1 - 0.048 14.1 1.0 6.2 7.3 0.0 3.7 3 1 0 4 4 4 0 SUKH-3 immunity protein DUF1459 PF07312.11 KDO20430.1 - 1.6 9.0 4.1 5.2 7.4 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1459) XRN_M PF17846.1 KDO20431.1 - 6.9e-89 298.8 0.3 8e-63 212.9 0.5 2.1 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 KDO20431.1 - 1.9e-88 296.0 0.0 3.3e-88 295.2 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KDO20431.1 - 1.9e-27 96.3 0.0 3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KDO20431.1 - 8.4e-19 67.5 2.7 8.6e-18 64.2 0.2 2.7 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KDO20431.1 - 0.00019 21.6 0.0 0.00058 20.0 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain DUF1631 PF07793.11 KDO20431.1 - 0.44 8.9 3.3 0.75 8.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Ephrin_rec_like PF07699.13 KDO20432.1 - 0.00019 21.1 3.1 0.00057 19.6 3.1 1.8 1 0 0 1 1 1 1 Putative ephrin-receptor like Vault PF01505.18 KDO20432.1 - 0.09 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Major Vault Protein repeat domain Tetraspanin PF00335.20 KDO20432.1 - 0.57 9.8 4.0 2.2 7.9 1.8 2.2 2 0 0 2 2 2 0 Tetraspanin family Laminin_EGF PF00053.24 KDO20432.1 - 4.4 7.5 5.9 28 4.9 1.0 2.9 1 1 1 2 2 2 0 Laminin EGF domain MatE PF01554.18 KDO20433.1 - 9.7e-34 116.3 38.5 1.4e-17 63.9 12.2 2.6 3 0 0 3 3 3 2 MatE CCDC23 PF15674.5 KDO20434.1 - 0.004 17.1 10.5 0.0087 16.0 10.5 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 DUF2058 PF09831.9 KDO20434.1 - 0.089 12.9 8.2 0.15 12.2 8.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Casc1_N PF15927.5 KDO20434.1 - 2.2 7.9 9.8 3.1 7.5 9.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus OB_NTP_bind PF07717.16 KDO20435.1 - 6e-16 58.6 0.0 7.5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold KASH_CCD PF14662.6 KDO20437.1 - 0.0041 17.0 5.6 0.0064 16.3 5.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CCDC24 PF15669.5 KDO20437.1 - 0.011 15.7 2.3 0.018 14.9 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Phage_int_SAM_6 PF18644.1 KDO20437.1 - 0.077 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain Spc7 PF08317.11 KDO20437.1 - 0.23 10.3 4.1 0.35 9.7 4.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.6 KDO20437.1 - 0.25 11.4 2.6 0.41 10.7 2.6 1.3 1 0 0 1 1 1 0 FlxA-like protein Uso1_p115_C PF04871.13 KDO20437.1 - 0.25 11.7 5.7 0.4 11.0 5.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 KDO20437.1 - 0.26 11.4 6.4 0.52 10.4 6.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor U1snRNP70_N PF12220.8 KDO20437.1 - 0.36 11.5 2.0 0.73 10.5 2.0 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_13 PF13166.6 KDO20437.1 - 0.62 8.6 3.1 0.85 8.2 3.1 1.1 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 KDO20438.1 - 0.0006 19.9 7.6 0.0006 19.9 7.6 2.4 3 0 0 3 3 3 1 bZIP transcription factor DUF3573 PF12097.8 KDO20438.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2353 PF09789.9 KDO20438.1 - 0.19 11.1 6.6 0.27 10.5 6.6 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) eIF3_subunit PF08597.10 KDO20438.1 - 0.2 11.6 9.9 0.31 10.9 9.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 KDO20438.1 - 3.9 5.6 7.5 5.5 5.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PARG_cat PF05028.14 KDO20439.1 - 6.8e-100 334.6 0.0 8.9e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) B56 PF01603.20 KDO20440.1 - 1e-91 308.0 0.7 1.3e-91 307.6 0.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 KDO20440.1 - 4.4e-19 68.9 0.0 1.2e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 PH domain ZinT PF09223.11 KDO20440.1 - 0.0046 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment PH_11 PF15413.6 KDO20440.1 - 0.059 13.8 0.8 0.23 11.9 0.8 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 KDO20440.1 - 0.13 12.6 0.4 0.42 10.9 0.4 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Glyco_hydro_31 PF01055.26 KDO20441.1 - 1.9e-133 445.9 3.2 2.7e-133 445.4 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KDO20441.1 - 1.8e-20 73.0 0.2 1.7e-19 69.9 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KDO20441.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) SPRY PF00622.28 KDO20443.1 - 0.001 19.2 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BTB_2 PF02214.22 KDO20444.1 - 9.6e-12 45.1 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ANAPC5 PF12862.7 KDO20446.1 - 0.073 13.2 0.3 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 IQ PF00612.27 KDO20447.1 - 4.6e-15 53.9 43.2 0.0091 15.7 0.4 8.1 7 0 0 7 7 7 7 IQ calmodulin-binding motif RTC4 PF14474.6 KDO20447.1 - 0.05 13.8 0.4 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 RTC4-like domain Ribosomal_L3 PF00297.22 KDO20448.1 - 3.9e-19 68.9 0.8 9.2e-17 61.1 1.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Aa_trans PF01490.18 KDO20449.1 - 3.8e-37 128.0 1.4 1.2e-35 123.0 1.4 2.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1422 PF07226.11 KDO20449.1 - 0.25 11.4 4.9 0.38 10.8 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) zf-RING_11 PF17123.5 KDO20450.1 - 2.5e-05 23.9 0.5 2.5e-05 23.9 0.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO20450.1 - 8.5e-05 22.8 7.7 0.00022 21.4 7.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO20450.1 - 0.00013 21.7 10.0 0.00062 19.6 10.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO20450.1 - 0.00022 21.5 10.6 0.00077 19.7 10.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO20450.1 - 0.0031 17.5 4.5 0.0072 16.3 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO20450.1 - 0.014 15.3 9.5 0.037 13.9 9.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO20450.1 - 0.018 15.0 9.2 0.044 13.8 9.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 KDO20450.1 - 0.4 10.5 4.5 6.4 6.7 3.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit BROMI PF14961.6 KDO20452.1 - 2.9e-08 31.7 0.1 5.7e-06 24.1 0.0 2.1 2 0 0 2 2 2 2 Broad-minded protein Fer2_3 PF13085.6 KDO20453.1 - 5.8e-32 109.9 0.0 1.1e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KDO20453.1 - 5.1e-10 39.8 6.0 5.1e-10 39.8 6.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KDO20453.1 - 3.3e-07 30.3 4.2 3.3e-07 30.3 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KDO20453.1 - 3.9e-07 30.4 10.2 3.9e-07 30.4 10.2 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KDO20453.1 - 0.00012 22.0 1.8 0.0023 17.8 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KDO20453.1 - 0.037 14.6 8.7 0.037 14.6 8.7 2.5 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KDO20453.1 - 0.084 13.1 0.1 0.084 13.1 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 KDO20453.1 - 0.14 12.1 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Fer4_16 PF13484.6 KDO20453.1 - 0.26 12.3 9.1 1.9 9.5 1.2 3.1 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KDO20453.1 - 0.29 11.3 15.1 0.052 13.7 8.7 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain C2 PF00168.30 KDO20454.1 - 2.3e-10 40.7 0.0 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 C2 domain YihI PF04220.12 KDO20455.1 - 0.041 13.6 4.3 0.6 9.8 0.7 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) zf-MYND PF01753.18 KDO20456.1 - 2.1e-09 37.3 12.2 4.3e-09 36.3 12.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KDO20456.1 - 0.0017 18.6 7.9 0.0041 17.4 7.9 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding SNase PF00565.17 KDO20457.1 - 3.9e-49 165.6 0.0 2.1e-10 41.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KDO20457.1 - 3.2e-19 69.1 0.0 8.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain DUF1639 PF07797.14 KDO20457.1 - 0.069 13.1 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) TFA2_Winged_2 PF18121.1 KDO20457.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Aminotran_1_2 PF00155.21 KDO20458.1 - 3e-49 168.1 0.0 3.5e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KDO20458.1 - 5.7e-07 29.2 0.2 1e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KDO20458.1 - 1.3e-06 27.9 0.2 1.9e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KDO20458.1 - 0.00046 19.2 0.1 0.00074 18.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KDO20458.1 - 0.0005 18.9 0.1 0.00083 18.2 0.1 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KDO20458.1 - 0.00051 18.7 0.1 0.0009 17.9 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 KDO20459.1 - 1e-45 152.8 57.0 0.0001 23.0 0.0 23.4 24 1 0 24 24 24 9 WD domain, G-beta repeat HELP PF03451.14 KDO20459.1 - 8.5e-42 140.9 0.0 1.6e-16 59.9 0.0 3.7 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 KDO20459.1 - 8.1e-17 61.3 15.7 0.0007 19.8 0.1 14.3 9 6 7 17 17 17 6 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KDO20459.1 - 2.7e-07 29.3 1.1 0.055 11.8 0.0 4.1 4 0 0 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz EF-hand_1 PF00036.32 KDO20459.1 - 1.2e-05 24.5 0.3 2.2 8.0 0.0 4.1 3 1 1 4 4 4 2 EF hand Cytochrom_D1 PF02239.16 KDO20459.1 - 1.4e-05 23.8 0.0 0.0014 17.2 0.0 2.5 2 0 0 2 2 2 1 Cytochrome D1 heme domain EF-hand_6 PF13405.6 KDO20459.1 - 5.7e-05 22.7 0.3 1.5 8.9 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KDO20459.1 - 0.00081 19.8 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair WD40_like PF17005.5 KDO20459.1 - 0.003 16.9 0.0 5.3 6.3 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KDO20459.1 - 0.0037 16.3 5.9 9.3 5.1 0.1 5.8 5 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO20459.1 - 0.024 13.3 0.3 1.3 7.6 0.0 3.1 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Aminotran_1_2 PF00155.21 KDO20460.1 - 1.5e-48 165.8 0.0 1.8e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KDO20460.1 - 0.01 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Allinase Aminotran_MocR PF12897.7 KDO20460.1 - 0.044 12.6 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Presenilin PF01080.17 KDO20461.1 - 0.89 8.3 7.2 0.77 8.5 1.1 2.0 2 0 0 2 2 2 0 Presenilin DUF3381 PF11861.8 KDO20461.1 - 2.5 7.9 12.0 1.8 8.3 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PX PF00787.24 KDO20462.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 PX domain E1_dh PF00676.20 KDO20463.1 - 1.6e-87 293.3 0.0 1.9e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KDO20463.1 - 8.4e-06 25.6 0.0 0.00013 21.8 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KDO20463.1 - 0.017 14.3 0.0 0.043 13.0 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KDO20463.1 - 0.048 12.5 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain Spt5-NGN PF03439.13 KDO20464.1 - 5.7e-20 71.0 0.0 1.5e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KDO20464.1 - 3.5e-16 58.5 37.6 7.2e-06 25.8 0.2 8.3 8 1 0 8 8 8 5 KOW motif Spt5_N PF11942.8 KDO20464.1 - 3.6e-05 24.7 11.9 3.6e-05 24.7 11.9 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KN17_SH3 PF18131.1 KDO20464.1 - 0.0053 16.9 1.3 0.062 13.4 0.1 2.7 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain DUF3912 PF13051.6 KDO20464.1 - 0.0086 16.3 7.3 0.087 13.1 0.1 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF3912) DUF4265 PF14085.6 KDO20464.1 - 0.0091 16.0 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4265) DUF150_C PF17384.2 KDO20464.1 - 0.02 15.0 3.2 8 6.7 0.5 3.6 3 0 0 3 3 3 0 RimP C-terminal SH3 domain Kinesin PF00225.23 KDO20465.1 - 5.8e-88 295.0 0.0 1.4e-87 293.7 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO20465.1 - 2.2e-15 56.9 0.0 6.1e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 KDO20465.1 - 0.0063 16.3 0.3 39 4.3 0.0 5.1 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat WD40_alt PF14077.6 KDO20465.1 - 0.097 12.5 1.9 43 4.1 0.0 4.7 4 0 0 4 4 4 0 Alternative WD40 repeat motif cNMP_binding PF00027.29 KDO20466.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Phage_AlpA PF05930.12 KDO20466.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) PUF PF00806.19 KDO20468.1 - 0.056 13.2 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Clusterin PF01093.17 KDO20468.1 - 2.2 7.2 4.8 15 4.5 0.5 2.5 3 0 0 3 3 3 0 Clusterin XRN_M PF17846.1 KDO20469.1 - 1.3e-161 538.5 0.0 1.9e-161 538.0 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KDO20469.1 - 3.6e-96 321.3 0.3 6.8e-96 320.4 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Helicase_C PF00271.31 KDO20470.1 - 2.9e-12 46.9 0.0 5.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO20470.1 - 2.9e-06 27.2 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase XPG_I PF00867.18 KDO20470.1 - 2.8e-05 24.4 0.2 0.00012 22.4 0.1 2.3 2 0 0 2 2 2 1 XPG I-region HA2 PF04408.23 KDO20470.1 - 0.0019 18.5 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 KDO20470.1 - 0.0024 18.2 0.0 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain XPG_I_2 PF12813.7 KDO20470.1 - 0.0072 15.8 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing DUF3246 PF11596.8 KDO20470.1 - 0.083 12.3 2.6 5.3 6.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) XPG_N PF00752.17 KDO20470.1 - 0.14 12.7 0.0 1.9 9.0 0.0 2.7 3 0 0 3 3 3 0 XPG N-terminal domain AAA_23 PF13476.6 KDO20470.1 - 0.21 12.0 0.1 0.39 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Nop16 PF09420.10 KDO20471.1 - 1.5e-23 84.0 7.1 3.3e-15 56.7 0.6 2.0 1 1 0 2 2 2 2 Ribosome biogenesis protein Nop16 DUF823 PF05689.11 KDO20471.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) COesterase PF00135.28 KDO20473.1 - 7.6e-17 61.4 1.0 1.8e-16 60.1 1.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KDO20473.1 - 5.9e-16 59.0 0.1 9.5e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO20473.1 - 1.1e-07 32.7 1.1 1.8e-07 32.0 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO20473.1 - 0.00025 20.8 0.2 0.00038 20.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO20473.1 - 0.00056 19.4 0.4 0.0075 15.8 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO20473.1 - 0.0048 16.2 0.9 0.32 10.2 0.2 2.4 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KDO20473.1 - 0.032 13.3 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Chlorophyllase2 PF12740.7 KDO20473.1 - 0.032 13.1 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme FSH1 PF03959.13 KDO20473.1 - 0.061 13.0 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KDO20473.1 - 0.15 11.5 0.5 9.3 5.7 0.0 2.8 3 0 0 3 3 3 0 Esterase PHB depolymerase DLH PF01738.18 KDO20473.1 - 0.2 11.2 1.1 0.33 10.5 0.1 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2457 PF10446.9 KDO20473.1 - 1.6 7.8 3.2 2.3 7.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase_Tyr PF07714.17 KDO20474.1 - 7.3e-55 186.0 0.0 8.8e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20474.1 - 2.2e-53 181.3 0.0 2.8e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO20474.1 - 0.0033 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO20474.1 - 0.011 15.0 0.0 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KDO20475.1 - 9.4e-52 176.0 0.0 2.1e-51 174.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RyR PF02026.16 KDO20475.1 - 8.6e-43 144.4 0.0 3.2e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 RyR domain Pkinase_Tyr PF07714.17 KDO20475.1 - 1e-25 90.5 0.0 2e-17 63.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KDO20475.1 - 2.7e-06 27.5 0.4 0.094 12.6 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO20475.1 - 4.9e-05 22.8 0.0 9.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO20475.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 KDO20475.1 - 0.0075 16.8 0.0 0.58 10.7 0.1 2.4 1 1 1 2 2 2 1 PH domain HrpB7 PF09486.10 KDO20475.1 - 0.066 13.6 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4203 PF13886.6 KDO20476.1 - 1e-11 44.9 21.3 1.9e-11 44.0 21.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) WD40 PF00400.32 KDO20477.1 - 2.6e-34 116.6 15.5 7.6e-08 32.9 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 KDO20477.1 - 7.5e-29 99.5 1.9 2.6e-28 97.8 1.8 2.0 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KDO20477.1 - 1.9e-14 53.7 0.1 0.0041 17.4 0.0 5.4 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO20477.1 - 2e-05 24.5 0.0 0.12 12.2 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KDO20477.1 - 5.8e-05 22.2 1.6 0.38 9.7 0.0 3.9 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 KDO20477.1 - 0.00025 20.8 0.1 0.00045 20.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WD40_like PF17005.5 KDO20477.1 - 0.0011 18.4 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain ELYS-bb PF16687.5 KDO20477.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Spc7 PF08317.11 KDO20477.1 - 0.018 13.9 2.8 0.026 13.4 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein U-box PF04564.15 KDO20477.1 - 0.04 14.1 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain Nbas_N PF15492.6 KDO20477.1 - 0.051 12.9 0.5 0.11 11.9 0.3 1.6 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KDO20477.1 - 0.061 11.6 0.0 0.2 9.9 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DivIVA PF05103.13 KDO20477.1 - 0.4 10.8 3.5 0.74 9.9 3.5 1.3 1 0 0 1 1 1 0 DivIVA protein TSNAXIP1_N PF15739.5 KDO20477.1 - 0.42 11.0 3.5 0.16 12.4 0.5 1.7 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus TMF_TATA_bd PF12325.8 KDO20477.1 - 1.1 9.5 3.4 3.1 8.0 3.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RIC1 PF07064.13 KDO20478.1 - 4.5e-12 45.9 1.8 6.1e-12 45.5 0.4 1.9 2 0 0 2 2 2 1 RIC1 ACBP PF00887.19 KDO20478.1 - 1.6e-11 44.2 0.0 3.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein PDZ_6 PF17820.1 KDO20478.1 - 8.7e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 KDO20478.1 - 0.0017 18.6 0.1 0.4 11.0 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PDZ PF00595.24 KDO20478.1 - 0.0047 17.3 0.0 0.0085 16.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain US22 PF02393.16 KDO20478.1 - 0.012 15.8 0.2 0.15 12.3 0.0 2.8 3 1 0 3 3 3 0 US22 like Dynein_light PF01221.18 KDO20479.1 - 1.2e-24 86.4 0.2 1.4e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 COOH-NH2_lig PF14395.6 KDO20479.1 - 0.031 13.5 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF4854 PF16146.5 KDO20479.1 - 0.083 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) TPH PF13868.6 KDO20481.1 - 8e-34 116.7 94.5 8e-34 116.7 94.5 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain MORN PF02493.20 KDO20484.1 - 1.2e-23 81.5 36.0 1.2e-05 24.9 1.8 7.3 7 0 0 7 7 7 7 MORN repeat Ald_Xan_dh_C2 PF02738.18 KDO20485.1 - 2.5e-152 508.2 0.8 3.4e-152 507.7 0.8 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 KDO20485.1 - 8e-28 96.3 1.7 1.3e-27 95.6 0.4 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 KDO20485.1 - 1.2e-20 73.9 0.1 2.7e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KDO20485.1 - 2.4e-20 73.0 0.3 5.5e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KDO20485.1 - 2.7e-09 37.1 0.1 1.1e-08 35.1 0.1 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KDO20485.1 - 1.3e-05 25.0 0.5 5e-05 23.2 0.5 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 KDO20485.1 - 0.083 12.7 1.1 0.22 11.4 1.1 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B RIH_assoc PF08454.11 KDO20486.1 - 5.8e-25 87.1 3.0 1.5e-24 85.8 0.2 3.2 3 0 0 3 3 3 1 RyR and IP3R Homology associated Ion_trans PF00520.31 KDO20486.1 - 5.7e-12 45.4 8.6 2.5e-11 43.3 8.6 1.9 1 1 0 1 1 1 1 Ion transport protein RYDR_ITPR PF01365.21 KDO20486.1 - 1.9e-07 30.7 1.9 2.3e-06 27.2 0.0 3.5 4 1 0 4 4 4 1 RIH domain Ins145_P3_rec PF08709.11 KDO20487.1 - 7.2e-07 28.6 0.0 8.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF547 PF04784.14 KDO20488.1 - 3.4e-15 56.2 0.0 6.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DUF1729 PF08354.10 KDO20489.1 - 2.1e-136 454.5 0.0 3.8e-136 453.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 KDO20489.1 - 4.3e-75 251.5 0.0 9.6e-38 130.1 0.0 2.6 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 KDO20489.1 - 1.7e-47 162.5 3.9 5.5e-45 154.2 0.2 4.6 3 2 0 3 3 3 1 Acyl transferase domain FAS_I_H PF18314.1 KDO20489.1 - 3.3e-37 128.1 0.0 2.4e-24 86.1 0.1 2.3 2 0 0 2 2 2 2 Fatty acid synthase type I helical domain SAT PF16073.5 KDO20489.1 - 4.3e-32 111.7 1.3 9.2e-32 110.7 1.3 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KDO20489.1 - 7.9e-21 74.8 0.4 1.7e-20 73.7 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_meander PF17951.1 KDO20489.1 - 2e-16 60.1 0.0 4.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain ACPS PF01648.20 KDO20489.1 - 1.2e-14 54.4 0.0 2.4e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydratas PF01575.19 KDO20489.1 - 2.3e-14 53.0 0.2 1e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain Ketoacyl-synt_C PF02801.22 KDO20489.1 - 5.9e-11 42.4 0.0 1.7e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.6 KDO20489.1 - 0.013 15.7 0.3 0.053 13.6 0.1 2.3 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase TRP PF06011.12 KDO20490.1 - 7.4e-07 28.2 16.4 1.1e-05 24.3 3.9 2.4 2 1 1 3 3 3 2 Transient receptor potential (TRP) ion channel TMEM208_SND2 PF05620.11 KDO20490.1 - 0.3 10.9 9.0 0.36 10.6 0.5 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF3810 PF12725.7 KDO20490.1 - 0.58 9.5 5.7 1.2 8.5 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2985 PF11204.8 KDO20490.1 - 1.4 9.1 8.9 1.1 9.5 5.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2985) Yip1 PF04893.17 KDO20490.1 - 1.6 8.5 25.1 0.25 11.1 13.3 2.5 1 1 1 2 2 2 0 Yip1 domain COX2_TM PF02790.15 KDO20490.1 - 1.7 8.9 6.6 7.1 6.9 5.9 2.4 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Nodulin_late PF07127.11 KDO20490.1 - 3.4 8.1 6.6 6.7 7.1 0.2 2.5 2 0 0 2 2 2 0 Late nodulin protein DHHC PF01529.20 KDO20490.1 - 8.7 6.5 12.3 0.68 10.0 6.5 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4834 PF16118.5 KDO20491.1 - 0.02 15.8 0.7 0.81 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 KDO20491.1 - 0.19 11.6 0.2 0.43 10.4 0.0 1.6 2 0 0 2 2 2 0 TMEM9 Cyclin_N PF00134.23 KDO20492.1 - 3.5e-25 88.2 0.6 3.5e-25 88.2 0.6 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO20492.1 - 1.8e-05 24.8 1.9 3.9e-05 23.7 0.4 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain PAP_central PF04928.17 KDO20493.1 - 1.6e-75 253.3 0.0 2.3e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KDO20493.1 - 1.9e-16 60.1 1.7 3.8e-10 39.7 0.0 2.6 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KDO20493.1 - 1.2e-05 25.5 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D5 PF17406.2 KDO20493.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Bromodomain PF00439.25 KDO20494.1 - 4.3e-20 71.6 0.0 8.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 KDO20494.1 - 2.7e-10 40.2 0.4 5.3e-10 39.3 0.4 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Paf67 PF10255.9 KDO20494.1 - 0.016 14.2 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 CCSAP PF15748.5 KDO20495.1 - 0.14 12.3 3.8 0.17 12.1 3.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Methyltransf_4 PF02390.17 KDO20496.1 - 1.8e-48 164.3 0.0 2.2e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KDO20496.1 - 0.00034 21.2 0.0 0.00078 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO20496.1 - 0.0081 15.7 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KDO20496.1 - 0.021 14.6 0.1 0.048 13.5 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KDO20496.1 - 0.022 15.5 0.0 0.039 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO20496.1 - 0.026 15.2 0.0 0.063 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ank_5 PF13857.6 KDO20499.1 - 5.9e-12 45.6 0.3 3.3e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20499.1 - 4.2e-11 43.3 0.1 3.3e-05 24.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20499.1 - 9.3e-09 35.7 0.1 1e-05 26.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO20499.1 - 1.5e-06 28.4 0.1 0.0011 19.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO20499.1 - 1.4e-05 25.1 0.1 0.00034 20.8 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeat cNMP_binding PF00027.29 KDO20500.1 - 1.4e-11 44.3 0.1 2.5e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO20500.1 - 4.8e-08 32.5 11.7 6.5e-08 32.1 11.7 1.2 1 0 0 1 1 1 1 Ion transport protein RNase_T PF00929.24 KDO20500.1 - 0.079 13.5 2.8 0.59 10.7 0.3 2.5 3 0 0 3 3 3 0 Exonuclease cNMP_binding PF00027.29 KDO20501.1 - 1.3e-12 47.6 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO20501.1 - 8.5e-11 41.6 10.1 1.3e-10 40.9 10.1 1.3 1 0 0 1 1 1 1 Ion transport protein DIX PF00778.17 KDO20502.1 - 2.3e-07 30.6 0.0 4.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 DIX domain DnaJ PF00226.31 KDO20502.1 - 7.4e-05 22.8 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain CMS1 PF14617.6 KDO20503.1 - 2.6e-27 95.7 3.1 2.6e-27 95.7 3.1 2.0 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KDO20503.1 - 0.00027 20.8 0.0 0.00067 19.5 0.0 1.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase YL1 PF05764.13 KDO20503.1 - 0.013 15.6 7.1 0.018 15.2 7.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDT1_C PF16679.5 KDO20503.1 - 0.036 14.5 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DUF4611 PF15387.6 KDO20503.1 - 1.6 9.0 7.8 3.4 7.9 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 KDO20504.1 - 2.2e-74 250.1 0.0 2.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20504.1 - 3.1e-29 102.0 0.0 4.1e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO20504.1 - 0.00014 20.8 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO20504.1 - 0.00015 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20504.1 - 0.00055 19.3 0.0 0.0014 18.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 KDO20504.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 KDO20504.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RabGAP-TBC PF00566.18 KDO20505.1 - 6.3e-44 150.2 0.5 1.8e-42 145.4 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 KDO20505.1 - 8.2e-13 48.8 0.2 1.7e-12 47.8 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO20505.1 - 0.012 16.1 1.1 0.049 14.1 1.1 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain AAA PF00004.29 KDO20506.1 - 5.6e-39 133.6 0.0 1.1e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KDO20506.1 - 3.4e-17 62.1 0.1 6.8e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KDO20506.1 - 3.7e-13 49.0 0.4 9.5e-13 47.7 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KDO20506.1 - 1.9e-07 31.4 0.1 5e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KDO20506.1 - 9.5e-07 28.9 0.3 9.8e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO20506.1 - 8.1e-06 26.3 0.1 4.3e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO20506.1 - 4.3e-05 23.8 0.1 0.0027 18.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO20506.1 - 0.00038 20.6 0.0 0.00084 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KDO20506.1 - 0.00049 20.0 0.9 0.2 11.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KDO20506.1 - 0.0018 18.0 0.1 0.0087 15.8 0.1 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KDO20506.1 - 0.0068 16.1 0.6 0.46 10.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 KDO20506.1 - 0.0073 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 KDO20506.1 - 0.011 15.8 0.2 0.037 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 KDO20506.1 - 0.021 14.1 0.2 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 KDO20506.1 - 0.023 15.3 0.8 0.094 13.3 0.0 2.5 2 2 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KDO20506.1 - 0.026 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KDO20506.1 - 0.029 14.1 0.1 0.16 11.6 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KDO20506.1 - 0.033 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KDO20506.1 - 0.041 13.8 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FlxA PF14282.6 KDO20506.1 - 0.045 13.8 2.4 0.17 11.9 1.3 2.2 2 1 0 2 2 2 0 FlxA-like protein ATPase PF06745.13 KDO20506.1 - 0.06 12.7 0.6 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 KDO20506.1 - 0.096 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KDO20506.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pkinase PF00069.25 KDO20507.1 - 1.7e-54 184.9 0.0 2.2e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20507.1 - 4e-21 75.5 0.0 5.4e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO20507.1 - 2e-11 43.8 0.1 1.6e-10 40.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO20507.1 - 0.0015 18.2 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KDO20507.1 - 0.0038 16.6 0.2 0.0083 15.5 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO20507.1 - 0.0069 16.3 0.1 0.035 14.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KDO20508.1 - 1.6e-151 503.1 0.0 5e-57 193.3 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20508.1 - 4e-52 177.1 0.0 8.1e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 KDO20508.1 - 3.2e-18 66.1 0.0 6.2e-07 29.0 0.0 3.5 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 KDO20508.1 - 2.3e-07 30.4 4.2 0.017 14.5 0.1 3.4 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_DNA_binding PF00216.21 KDO20508.1 - 0.15 12.2 0.0 1e+02 3.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial DNA-binding protein RAMP4 PF06624.12 KDO20508.1 - 0.68 10.0 2.8 5.9 7.0 0.1 3.0 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 Pkinase PF00069.25 KDO20509.1 - 1e-75 254.5 0.0 1.3e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20509.1 - 3.3e-36 124.9 0.0 4.4e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO20509.1 - 6.6e-06 25.6 0.1 1.2e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20509.1 - 7.8e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO20509.1 - 0.00026 19.9 0.0 0.0004 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Chordopox_A35R PF05989.12 KDO20509.1 - 0.0078 16.1 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Chordopoxvirus A35R protein DUF5051 PF16473.5 KDO20509.1 - 0.042 13.8 0.0 0.089 12.8 0.0 1.6 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like APH PF01636.23 KDO20509.1 - 0.06 13.3 0.8 0.4 10.6 0.0 2.4 2 2 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO20510.1 - 9.9e-74 248.0 0.0 1.2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20510.1 - 4.6e-36 124.4 0.0 6.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO20510.1 - 3e-06 26.8 0.1 4.9e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20510.1 - 9.3e-05 21.9 0.2 0.00054 19.4 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO20510.1 - 0.0024 16.7 0.6 0.0035 16.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KDO20510.1 - 0.016 14.7 0.1 0.037 13.5 0.1 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KDO20510.1 - 0.029 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO20511.1 - 2.6e-74 249.9 0.0 3e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20511.1 - 4.1e-34 118.0 0.0 5.1e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO20511.1 - 4.3e-06 26.2 0.0 7.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20511.1 - 4.2e-05 23.0 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO20511.1 - 9e-05 22.5 0.0 0.25 11.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO20511.1 - 0.0028 17.3 0.4 0.04 13.5 0.1 2.1 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KDO20511.1 - 0.022 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KDO20511.1 - 0.046 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Act-Frag_cataly PF09192.10 KDO20511.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic FTA2 PF13095.6 KDO20511.1 - 0.15 11.7 0.0 2.9 7.5 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AAA_5 PF07728.14 KDO20512.1 - 7.5e-94 311.1 0.0 1.1e-38 132.3 0.0 3.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO20512.1 - 2e-08 34.6 0.3 0.00044 20.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KDO20512.1 - 2e-07 31.5 10.2 0.009 16.4 0.0 5.5 4 2 0 4 4 4 2 AAA ATPase domain Mg_chelatase PF01078.21 KDO20512.1 - 3.3e-05 23.4 0.5 0.26 10.7 0.0 4.2 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KDO20512.1 - 0.00073 20.1 0.2 0.97 9.9 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_7 PF12775.7 KDO20512.1 - 0.0011 18.5 0.0 0.034 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KDO20512.1 - 0.0038 17.4 0.0 1.4 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 KDO20512.1 - 0.0084 15.8 0.0 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KDO20512.1 - 0.0087 16.4 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KDO20512.1 - 0.0094 15.7 0.0 14 5.4 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 KDO20512.1 - 0.011 16.1 0.0 1.6 9.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KDO20512.1 - 0.012 15.6 0.0 2.3 8.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KDO20512.1 - 0.015 15.0 0.0 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 KDO20512.1 - 0.019 14.8 0.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO20512.1 - 0.028 15.0 0.1 0.74 10.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_lid_7 PF17867.1 KDO20512.1 - 0.046 13.9 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Midasin AAA lid domain VWA_2 PF13519.6 KDO20512.1 - 0.056 14.1 0.1 0.31 11.7 0.0 2.4 2 0 0 2 2 1 0 von Willebrand factor type A domain Roc PF08477.13 KDO20512.1 - 0.063 13.5 0.0 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KDO20512.1 - 0.12 12.3 0.1 26 4.7 0.0 3.6 4 0 0 4 4 3 0 NACHT domain Sgf11_N PF18519.1 KDO20512.1 - 0.15 11.6 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain TIP49 PF06068.13 KDO20512.1 - 0.16 11.2 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain Pkinase PF00069.25 KDO20513.1 - 1.6e-72 244.1 0.0 2.6e-72 243.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RPN2_C PF18004.1 KDO20513.1 - 7.1e-39 133.3 3.3 2.2e-38 131.7 3.3 1.8 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KDO20513.1 - 6.6e-34 114.6 25.0 6.4e-07 29.5 0.1 8.1 8 0 0 8 8 8 6 Proteasome/cyclosome repeat Pkinase_Tyr PF07714.17 KDO20513.1 - 2.3e-31 109.0 0.0 4.8e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KDO20513.1 - 1.1e-20 73.7 3.1 8.4e-11 42.1 0.0 5.5 5 0 0 5 5 5 4 HEAT repeats Kinase-like PF14531.6 KDO20513.1 - 5e-07 29.3 0.0 4.5e-06 26.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like HEAT_EZ PF13513.6 KDO20513.1 - 0.00079 19.9 0.5 0.12 13.0 0.0 4.4 4 0 0 4 4 4 1 HEAT-like repeat Pkinase_fungal PF17667.1 KDO20513.1 - 0.0013 17.6 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase HEAT PF02985.22 KDO20513.1 - 0.0034 17.5 0.9 1.8 9.1 0.1 4.8 5 0 0 5 5 3 1 HEAT repeat Kdo PF06293.14 KDO20513.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO20513.1 - 0.14 12.1 3.6 0.18 11.7 0.1 2.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family FTA2 PF13095.6 KDO20513.1 - 0.21 11.2 0.4 14 5.2 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 KDO20514.1 - 0.00039 21.0 0.2 0.098 13.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20514.1 - 0.02 15.2 0.1 0.092 13.1 0.0 2.2 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20514.1 - 0.023 15.3 0.3 0.085 13.5 0.1 2.0 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Peptidase_M6 PF05547.11 KDO20514.1 - 0.058 11.7 0.0 0.069 11.5 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Ank_3 PF13606.6 KDO20514.1 - 0.14 12.8 0.2 42 5.2 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat DHC_N1 PF08385.12 KDO20515.1 - 2.7e-154 514.9 0.0 2.7e-154 514.9 0.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KDO20515.1 - 7.7e-154 511.5 0.2 4.9e-153 508.9 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO20515.1 - 6.5e-122 407.5 14.7 2.2e-121 405.7 9.9 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO20515.1 - 1.7e-101 338.9 0.0 6.8e-101 337.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KDO20515.1 - 2.8e-96 322.4 0.0 1e-94 317.2 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KDO20515.1 - 7.9e-87 290.0 0.3 7.9e-87 290.0 0.3 4.2 6 0 0 6 6 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO20515.1 - 2.9e-72 242.0 1.2 1.5e-68 229.9 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KDO20515.1 - 1e-59 201.0 0.0 3.2e-59 199.4 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO20515.1 - 1.1e-43 148.1 0.0 1.9e-41 140.9 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KDO20515.1 - 2.2e-39 135.5 16.8 1.4e-24 86.8 0.5 2.5 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KDO20515.1 - 2.4e-25 89.1 0.1 7.6e-24 84.2 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KDO20515.1 - 2.7e-17 63.0 0.2 5.3e-07 29.7 0.0 5.8 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KDO20515.1 - 7.9e-17 61.3 0.3 7.1e-16 58.3 0.0 2.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 KDO20515.1 - 4e-07 30.4 0.1 0.16 12.3 0.0 5.7 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 KDO20515.1 - 0.00012 22.5 1.0 0.28 11.6 0.0 4.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO20515.1 - 0.0016 18.8 11.2 0.19 12.1 0.0 6.1 6 0 0 6 6 4 1 AAA ATPase domain ABC_tran PF00005.27 KDO20515.1 - 0.0022 18.5 0.0 37 4.8 0.0 4.6 3 1 0 3 3 3 0 ABC transporter Roc PF08477.13 KDO20515.1 - 0.0036 17.5 0.2 0.17 12.1 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KDO20515.1 - 0.0056 16.4 1.9 0.66 9.8 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain TniB PF05621.11 KDO20515.1 - 0.0073 15.7 0.1 4 6.8 0.0 3.2 3 0 0 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 KDO20515.1 - 0.0093 16.5 0.2 3.6 8.2 0.0 3.8 4 0 0 4 4 2 1 AAA domain UPF0242 PF06785.11 KDO20515.1 - 0.014 15.5 0.4 0.014 15.5 0.4 3.4 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus RsgA_GTPase PF03193.16 KDO20515.1 - 0.02 14.8 0.4 6.8 6.6 0.1 3.5 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 KDO20515.1 - 0.025 13.9 0.0 3.5 7.0 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KDO20515.1 - 0.074 12.8 0.9 17 5.0 0.1 3.8 3 0 0 3 3 3 0 AAA domain MSA-2c PF12238.8 KDO20515.1 - 0.21 11.6 1.5 0.77 9.7 0.1 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c MMR_HSR1 PF01926.23 KDO20515.1 - 0.63 10.1 5.4 13 5.9 0.1 4.0 4 0 0 4 4 3 0 50S ribosome-binding GTPase Laminin_II PF06009.12 KDO20515.1 - 1.8 8.6 19.5 0.0072 16.3 3.8 4.2 3 1 0 3 3 2 0 Laminin Domain II Rotamase PF00639.21 KDO20516.1 - 8.8e-25 87.5 0.0 9.9e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KDO20516.1 - 3.8e-22 79.0 0.0 4.1e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KDO20516.1 - 0.00014 22.7 0.0 0.00016 22.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain SelR PF01641.18 KDO20517.1 - 1.9e-47 160.3 0.0 2.2e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KDO20517.1 - 0.0035 17.0 0.5 0.34 10.7 0.1 2.3 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 KDO20517.1 - 0.024 14.1 0.6 6.5 6.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Cytochrome_C7 PF14522.6 KDO20517.1 - 0.053 13.5 4.0 0.22 11.5 4.0 1.8 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrome_CBB3 PF13442.6 KDO20517.1 - 4 7.8 9.5 6.6 7.1 1.8 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III FAM194 PF14977.6 KDO20518.1 - 3.4e-09 36.3 0.0 4.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 FAM194 protein SNF2_N PF00176.23 KDO20519.1 - 1.5e-52 178.4 0.0 4.3e-52 177.0 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KDO20519.1 - 6.5e-08 32.8 0.0 1.7e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO20519.1 - 4.5e-06 26.5 0.0 9.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ORC2 PF04084.14 KDO20519.1 - 0.032 13.2 0.1 0.055 12.4 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 2 BUD22 PF09073.10 KDO20519.1 - 3.2 7.0 23.6 0.84 8.9 20.3 1.6 2 0 0 2 2 2 0 BUD22 WD40 PF00400.32 KDO20520.1 - 5.9e-42 140.9 11.9 3.3e-14 53.1 1.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 KDO20520.1 - 1.4e-17 64.1 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 KDO20520.1 - 7.3e-15 55.0 0.0 2.4e-06 27.8 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO20520.1 - 3.1e-08 33.7 0.9 4.3e-05 23.5 0.1 2.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KDO20520.1 - 5.7e-06 25.3 0.2 0.63 8.7 0.0 4.0 2 1 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 KDO20520.1 - 0.00026 19.8 2.0 0.54 8.8 0.1 3.3 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO20520.1 - 0.0029 16.6 0.4 0.28 10.1 0.1 3.2 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KDO20520.1 - 0.0037 15.8 0.0 0.0052 15.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 KDO20520.1 - 0.0084 15.5 0.0 0.043 13.1 0.0 1.9 1 1 1 2 2 2 1 WD40-like domain CSN8_PSD8_EIF3K PF10075.9 KDO20521.1 - 9e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 KDO20521.1 - 0.014 15.9 0.0 0.24 11.9 0.0 2.2 2 0 0 2 2 2 0 PCI domain RabGAP-TBC PF00566.18 KDO20522.1 - 1.4e-51 175.3 0.1 1.9e-51 174.8 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 KDO20522.1 - 0.00065 19.5 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain RRM_1 PF00076.22 KDO20523.1 - 8.6e-22 76.8 0.0 1.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO20523.1 - 2.4e-05 24.1 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KDO20523.1 - 0.00027 20.5 0.0 0.00036 20.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KDO20523.1 - 0.0018 18.3 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 RRM_Rrp7 PF17799.1 KDO20523.1 - 0.19 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Glyco_transf_22 PF03901.17 KDO20524.1 - 6.9e-105 351.7 9.4 8.4e-105 351.4 9.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EamA PF00892.20 KDO20525.1 - 7.6e-18 65.0 38.4 5.5e-10 39.6 17.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KDO20525.1 - 0.0016 18.0 19.5 0.078 12.5 20.0 2.7 1 1 0 1 1 1 1 Solute carrier family 35 DUF3955 PF13127.6 KDO20525.1 - 0.0019 18.0 1.0 0.0019 18.0 1.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) 2OG-FeII_Oxy_3 PF13640.6 KDO20529.1 - 1.6e-20 73.8 0.0 2.6e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KDO20529.1 - 4.3e-10 40.1 0.0 6.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Elicitin PF00964.17 KDO20530.1 - 6.3e-07 29.4 1.7 1.1e-06 28.7 1.7 1.5 1 0 0 1 1 1 1 Elicitin Ank_2 PF12796.7 KDO20531.1 - 1.3e-23 83.3 2.8 9.8e-05 22.9 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20531.1 - 5.3e-22 77.9 11.5 2.5e-05 24.7 0.1 7.6 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20531.1 - 6.7e-16 58.2 12.2 0.054 13.8 0.1 8.8 3 2 7 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20531.1 - 6.5e-13 47.6 12.4 3.7 8.4 0.0 10.4 11 1 1 12 12 12 4 Ankyrin repeat DUF3322 PF11795.8 KDO20531.1 - 0.0046 17.0 0.4 9.7 6.2 0.1 3.4 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank PF00023.30 KDO20531.1 - 0.0046 17.3 11.4 19 5.9 0.1 7.6 5 4 3 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 KDO20531.1 - 0.026 14.4 5.6 3 7.8 0.0 5.8 6 2 3 9 9 9 0 Domain of unknown function (DUF5049) DUF1979 PF09322.10 KDO20531.1 - 0.074 13.0 0.0 4.7 7.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1979) Peptidase_M13 PF01431.21 KDO20532.1 - 1.2e-66 224.3 0.1 1.7e-66 223.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KDO20532.1 - 7.2e-48 164.2 0.2 2.3e-43 149.4 0.2 2.2 1 1 1 2 2 2 2 Peptidase family M13 EF-hand_7 PF13499.6 KDO20533.1 - 9.2e-16 58.1 0.0 7.4e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO20533.1 - 2.7e-14 51.6 0.2 0.00049 19.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO20533.1 - 4.7e-13 47.9 0.0 0.00057 19.6 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KDO20533.1 - 1.9e-08 33.4 2.7 0.004 16.6 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO20533.1 - 2.1e-06 27.5 0.2 0.00027 20.7 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair IQ PF00612.27 KDO20533.1 - 0.0027 17.3 6.6 0.0027 17.3 6.6 14.9 14 1 1 15 15 15 6 IQ calmodulin-binding motif CEBP_ZZ PF16366.5 KDO20533.1 - 0.27 11.5 18.7 0.53 10.6 5.0 2.7 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2951 PF11166.8 KDO20533.1 - 0.51 10.6 2.2 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-B_box PF00643.24 KDO20533.1 - 7.1 6.9 28.3 1.4 9.1 7.5 3.0 3 0 0 3 3 3 0 B-box zinc finger FAD-oxidase_C PF02913.19 KDO20534.1 - 7e-58 196.2 0.0 9.6e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KDO20534.1 - 7.9e-25 87.2 0.6 2.9e-17 62.7 0.4 2.5 1 1 1 2 2 2 2 FAD binding domain WD40 PF00400.32 KDO20535.1 - 8.5e-14 51.7 0.7 8.9e-10 39.0 0.4 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20535.1 - 3.1e-06 27.4 0.1 0.031 14.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO20535.1 - 0.00095 18.2 0.0 0.00097 18.2 0.0 1.1 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KDO20535.1 - 0.0037 17.2 0.2 0.54 10.3 0.1 2.2 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KDO20535.1 - 0.012 15.5 0.2 2.9 7.7 0.1 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KDO20535.1 - 0.014 13.4 0.0 0.015 13.3 0.0 1.0 1 0 0 1 1 1 0 IKI3 family TFIIIC_delta PF12657.7 KDO20535.1 - 0.17 11.8 2.7 5 7.0 2.7 2.0 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DPPIV_N PF00930.21 KDO20535.1 - 0.18 10.6 0.1 7.8 5.1 0.0 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Disintegrin PF00200.23 KDO20538.1 - 1.3e-28 99.6 120.4 3.4e-05 24.5 12.2 9.1 7 3 0 7 7 7 7 Disintegrin ResB PF05140.14 KDO20538.1 - 0.23 10.1 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 ResB-like family DDE_1 PF03184.19 KDO20540.1 - 1.1e-06 28.4 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KDO20540.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M13_N PF05649.13 KDO20544.1 - 1.5e-72 245.4 0.1 2.1e-72 245.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO20544.1 - 1.3e-34 119.6 0.1 2.2e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF1018 PF06252.12 KDO20544.1 - 0.23 12.5 0.6 4.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) AI-2E_transport PF01594.16 KDO20545.1 - 1.9e-11 43.7 19.4 1.9e-11 43.7 19.4 3.0 3 0 0 3 3 3 1 AI-2E family transporter DUF5541 PF17695.1 KDO20545.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5541) Ank_4 PF13637.6 KDO20546.1 - 1.9e-14 53.8 7.8 2.4e-06 28.0 0.3 4.7 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20546.1 - 4.7e-11 42.7 9.3 1.4e-05 25.3 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20546.1 - 3.1e-10 40.5 11.3 9.8e-06 26.1 4.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO20546.1 - 7e-06 26.0 4.4 2.3 9.0 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KDO20546.1 - 1.5 9.4 0.1 1.5 9.4 0.1 4.8 6 0 0 6 6 6 0 Ankyrin repeat WD40 PF00400.32 KDO20550.1 - 8.4e-44 146.7 29.9 1e-08 35.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20550.1 - 3.1e-16 59.4 2.4 0.00083 19.6 0.0 6.0 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KDO20550.1 - 1.2e-07 30.3 0.6 0.00037 18.6 0.3 2.3 1 1 1 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 KDO20550.1 - 6e-06 25.5 0.6 0.02 13.9 0.0 3.3 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO20550.1 - 3.6e-05 23.7 0.9 0.056 13.3 0.1 3.8 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KDO20550.1 - 0.0014 18.5 3.3 3.4 7.7 0.1 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KDO20550.1 - 0.013 14.3 2.8 1.1 7.9 0.1 3.2 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.14 KDO20550.1 - 0.039 13.0 0.4 0.63 9.0 0.2 2.5 2 1 0 2 2 2 0 Coatomer WD associated region TFIIIC_delta PF12657.7 KDO20550.1 - 0.38 10.7 10.1 18 5.2 7.1 3.7 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term FAM167 PF11652.8 KDO20552.1 - 0.37 11.3 2.2 10 6.7 0.0 3.0 2 1 1 3 3 3 0 FAM167 DNA_pol_A_exo1 PF01612.20 KDO20553.1 - 2.1e-18 66.6 0.0 6.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease PPR_2 PF13041.6 KDO20553.1 - 1.7e-12 47.3 0.0 2.7e-07 30.7 0.0 3.9 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 KDO20553.1 - 2e-08 34.2 0.0 0.13 12.4 0.1 5.0 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KDO20553.1 - 2.2e-06 27.5 0.0 3.3 8.2 0.0 5.6 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 KDO20553.1 - 3.7e-06 26.5 0.1 0.52 10.1 0.1 4.5 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KDO20553.1 - 0.0005 19.5 0.3 0.007 15.7 0.1 2.5 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP zf-CCCH PF00642.24 KDO20555.1 - 8.3e-18 63.8 18.4 1.4e-06 28.1 0.8 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO20555.1 - 1.9e-13 49.9 23.8 0.00011 22.1 4.3 3.5 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 KDO20555.1 - 2.8e-13 50.5 10.8 0.00034 21.3 0.6 3.3 2 1 1 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 KDO20555.1 - 3.1e-12 46.0 21.2 0.00026 20.7 4.3 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KDO20555.1 - 0.027 14.7 12.1 0.16 12.2 5.8 2.4 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KDO20555.1 - 0.054 14.0 14.1 3.6 8.2 0.7 4.0 3 1 1 4 4 4 0 RNA-binding, Nab2-type zinc finger TB2_DP1_HVA22 PF03134.19 KDO20555.1 - 0.17 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family V-SNARE_C PF12352.8 KDO20556.1 - 3.3e-08 33.7 0.7 3.3e-08 33.7 0.7 1.9 3 0 0 3 3 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KDO20556.1 - 1.8e-07 31.5 1.9 1.8e-07 31.5 1.9 2.5 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.12 KDO20556.1 - 0.0005 20.1 1.5 0.0005 20.1 1.5 2.2 2 1 1 3 3 3 1 Laminin Domain II SNARE PF05739.19 KDO20556.1 - 0.00072 19.5 0.9 0.014 15.4 0.1 2.5 2 0 0 2 2 2 1 SNARE domain TBCC_N PF16752.5 KDO20556.1 - 0.0059 17.0 3.2 0.17 12.3 0.0 2.9 3 0 0 3 3 3 1 Tubulin-specific chaperone C N-terminal domain Lebercilin PF15619.6 KDO20556.1 - 0.017 14.8 10.6 0.28 10.8 3.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 KDO20556.1 - 0.023 15.0 7.2 0.42 10.9 0.6 3.4 2 2 1 3 3 3 0 Uncharacterized conserved protein FliJ PF02050.16 KDO20556.1 - 0.06 13.6 10.7 0.26 11.5 1.2 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein DUF5113 PF17140.4 KDO20556.1 - 0.088 12.6 0.8 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Cytochrom_B562 PF07361.11 KDO20556.1 - 0.12 13.1 7.9 0.2 12.3 2.1 3.2 1 1 3 4 4 4 0 Cytochrome b562 Orf78 PF06024.12 KDO20556.1 - 0.13 12.6 0.2 0.28 11.5 0.2 1.7 1 1 0 1 1 1 0 Orf78 (ac78) DUF745 PF05335.13 KDO20556.1 - 0.17 11.6 15.1 0.021 14.6 6.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KDO20556.1 - 0.33 11.0 4.3 0.19 11.7 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MCU PF04678.13 KDO20556.1 - 0.33 11.0 3.3 2.8 8.0 3.3 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter FeoB_associated PF12669.7 KDO20556.1 - 0.46 10.9 1.7 0.79 10.2 1.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein YlqD PF11068.8 KDO20556.1 - 0.49 10.8 6.4 0.49 10.8 0.9 2.1 2 0 0 2 2 2 0 YlqD protein MAD PF05557.13 KDO20556.1 - 0.69 8.2 10.8 1.2 7.4 4.2 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF724 PF05266.14 KDO20556.1 - 1 9.2 6.2 2.7 7.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DLP_helical PF18709.1 KDO20556.1 - 1.4 8.1 6.2 0.18 11.0 0.9 1.9 2 0 0 2 2 2 0 Dynamin-like helical domain UPF0242 PF06785.11 KDO20556.1 - 1.5 8.9 8.2 33 4.5 8.2 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KDO20556.1 - 1.8 7.4 8.9 0.8 8.5 1.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 KDO20556.1 - 2 8.8 12.3 1.2 9.5 3.0 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BST2 PF16716.5 KDO20556.1 - 2.3 8.9 10.5 5.1 7.8 1.1 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 KDO20556.1 - 2.6 8.1 8.8 3.6 7.6 0.3 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_Mu_Gam PF07352.12 KDO20556.1 - 3.4 7.6 6.6 5.5 6.9 1.3 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DnaJ PF00226.31 KDO20557.1 - 4e-21 74.9 0.6 5.8e-21 74.4 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 KDO20557.1 - 8.6e-18 64.9 26.6 6.4e-16 58.8 11.3 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein TMEM52 PF14979.6 KDO20557.1 - 0.17 11.8 5.4 0.24 11.3 4.2 1.9 2 0 0 2 2 2 0 Transmembrane 52 Corona_S2 PF01601.16 KDO20557.1 - 8.9 4.7 5.8 14 4.0 5.8 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein HSP90 PF00183.18 KDO20559.1 - 1.8e-106 357.1 1.7 5.6e-102 342.3 0.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KDO20559.1 - 1.4e-09 38.4 0.2 2.8e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KDO20559.1 - 4e-09 36.4 0.1 9e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_transf_34 PF05637.12 KDO20560.1 - 7.5e-08 32.4 0.2 0.00036 20.3 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Pribosyltran_N PF13793.6 KDO20561.1 - 3e-42 143.2 0.1 1.1e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KDO20561.1 - 4.8e-22 78.9 0.2 2.1e-21 76.8 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KDO20561.1 - 8.7e-09 35.1 0.2 3e-08 33.4 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KDO20561.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TB2_DP1_HVA22 PF03134.19 KDO20562.1 - 6.3e-30 102.9 1.7 9.5e-30 102.4 1.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Amidohydro_1 PF01979.20 KDO20565.1 - 2.4e-15 56.7 0.1 3.3e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KDO20565.1 - 0.0002 21.2 0.2 0.00064 19.6 0.2 1.8 2 1 0 2 2 2 1 Amidohydrolase TPR_2 PF07719.17 KDO20566.1 - 2.2e-10 39.8 8.3 0.14 12.3 0.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat DUF1736 PF08409.11 KDO20566.1 - 3.8e-09 36.4 1.0 9e-09 35.2 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_14 PF13428.6 KDO20566.1 - 9.7e-09 35.3 9.3 0.064 14.1 0.3 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20566.1 - 1.9e-06 27.6 2.0 2.7 8.4 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20566.1 - 1.7e-05 25.2 9.4 0.029 14.9 0.4 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20566.1 - 1.8e-05 25.3 8.1 0.00066 20.3 0.6 5.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20566.1 - 7.7e-05 22.9 6.4 1.5 9.2 1.4 5.7 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20566.1 - 0.00048 19.8 9.1 5.9 6.9 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20566.1 - 0.0026 17.5 0.6 0.0026 17.5 0.6 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO20566.1 - 0.0096 16.0 0.5 0.0096 16.0 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20566.1 - 0.029 14.7 10.3 4.2 8.0 0.3 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO20566.1 - 0.061 14.0 1.1 20 6.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Tcf25 PF04910.14 KDO20566.1 - 0.063 12.3 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional repressor TCF25 MIT PF04212.18 KDO20566.1 - 0.073 13.1 2.0 2.5 8.3 0.2 3.0 1 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 KDO20566.1 - 0.092 11.6 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KDO20566.1 - 0.1 12.7 1.9 4.8 7.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 KDO20566.1 - 0.13 11.0 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Coatomer_E PF04733.14 KDO20566.1 - 0.2 11.0 0.1 0.36 10.2 0.1 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_11 PF13414.6 KDO20566.1 - 0.22 11.2 8.4 2.8 7.7 0.2 3.9 3 1 1 4 4 4 0 TPR repeat TPR_4 PF07721.14 KDO20566.1 - 0.34 11.6 6.1 5.5 7.9 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KDO20568.1 - 1.7e-36 125.9 0.0 2.3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20568.1 - 4.3e-35 121.4 0.0 7.3e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 KDO20568.1 - 0.0012 18.2 3.9 0.0022 17.4 3.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KDO20568.1 - 0.0023 17.6 0.1 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 GRA6 PF05084.13 KDO20568.1 - 0.054 13.4 0.4 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) CwsA PF10814.8 KDO20568.1 - 0.075 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA FNIP PF05725.12 KDO20568.1 - 0.5 10.6 2.0 4.3 7.6 0.0 3.2 2 1 1 3 3 3 0 FNIP Repeat LRR_8 PF13855.6 KDO20568.1 - 7.7 6.4 16.0 0.58 10.0 4.3 3.8 3 1 1 4 4 4 0 Leucine rich repeat tRNA-synt_1 PF00133.22 KDO20569.1 - 2.2e-143 478.7 0.0 3.7e-115 385.5 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KDO20569.1 - 1.6e-23 83.4 0.1 2.6e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KDO20569.1 - 3.7e-17 62.2 0.1 2.2e-08 33.3 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KDO20569.1 - 1.4e-05 24.6 0.0 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KDO20569.1 - 1.8e-05 24.5 0.6 4e-05 23.4 0.6 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Pilin_PilA PF14245.6 KDO20569.1 - 0.027 14.5 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Type IV pilin PilA tRNA-synt_1f PF01921.18 KDO20569.1 - 0.056 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Bacillus_HBL PF05791.11 KDO20569.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) tRNA-synt_1_2 PF13603.6 KDO20569.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Abhydrolase_3 PF07859.13 KDO20570.1 - 2.5e-23 83.1 0.8 1.3e-10 41.5 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KDO20570.1 - 1.4e-15 57.0 0.0 3.9e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Far-17a_AIG1 PF04750.14 KDO20571.1 - 0.0049 16.2 15.4 0.01 15.1 15.5 1.5 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2433 PF10360.9 KDO20571.1 - 0.18 11.9 0.5 0.48 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) Far-17a_AIG1 PF04750.14 KDO20572.1 - 4.8e-06 26.0 12.7 1.3e-05 24.6 12.7 1.7 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2433 PF10360.9 KDO20572.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Cation_ATPase_C PF00689.21 KDO20574.1 - 0.22 11.2 4.1 0.61 9.8 4.1 1.9 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Far-17a_AIG1 PF04750.14 KDO20575.1 - 2.1e-05 23.9 14.2 0.0001 21.7 14.2 2.1 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.14 KDO20577.1 - 0.00041 19.7 10.8 0.00079 18.8 10.8 1.5 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein COG6 PF06419.11 KDO20579.1 - 7.6e-55 186.3 0.0 9.1e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 SWI2_SNF2 PF18766.1 KDO20581.1 - 1.8e-24 86.7 0.8 2.9e-24 86.0 0.8 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 KDO20581.1 - 3.2e-20 72.8 0.1 5.1e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO20581.1 - 2e-12 47.2 0.8 3.7e-12 46.4 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KDO20581.1 - 0.0086 15.3 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KDO20581.1 - 0.037 13.4 0.1 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KDO20581.1 - 0.05 13.9 0.4 0.38 11.0 0.4 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO20581.1 - 0.079 13.5 0.1 0.3 11.6 0.1 2.0 1 1 0 1 1 1 0 ABC transporter 2_5_RNA_ligase2 PF13563.6 KDO20582.1 - 5e-19 68.7 1.2 8.6e-09 35.5 0.1 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily CPDase PF07823.11 KDO20582.1 - 0.095 12.4 0.1 6.8 6.3 0.0 2.1 1 1 1 2 2 2 0 Cyclic phosphodiesterase-like protein Mesd PF10185.9 KDO20583.1 - 1.3e-07 31.6 0.2 1.7e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Lipase_GDSL_2 PF13472.6 KDO20584.1 - 8.3e-28 98.0 0.1 1.1e-27 97.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO20584.1 - 1.7e-15 57.5 0.0 8.4e-15 55.3 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KDO20584.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_transf_8C PF08437.10 KDO20584.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Lipase_GDSL_2 PF13472.6 KDO20585.1 - 1.9e-27 96.8 0.0 2.4e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO20585.1 - 2e-17 63.8 0.0 3.7e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-3CxxC_2 PF17180.4 KDO20586.1 - 6.9e-10 39.5 4.7 6.9e-10 39.5 4.7 1.9 2 0 0 2 2 2 1 Zinc-binding domain UPF0515 PF15135.6 KDO20586.1 - 0.01 15.2 3.4 0.016 14.6 3.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 KDO20586.1 - 0.39 11.2 11.9 50 4.5 11.9 2.9 1 1 0 1 1 1 0 Zinc-binding domain PLA2_inh PF02988.15 KDO20586.1 - 6.5 7.5 8.5 0.21 12.3 2.2 1.8 2 0 0 2 2 2 0 Phospholipase A2 inhibitor Complex1_LYR PF05347.15 KDO20587.1 - 0.0014 18.6 0.8 0.0021 18.0 0.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DNA_pol_E_B PF04042.16 KDO20588.1 - 4.8e-35 120.8 0.1 6.9e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KDO20588.1 - 1.6e-30 105.9 0.0 2.8e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain zf_UBZ PF18439.1 KDO20589.1 - 0.068 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger UbiA PF01040.18 KDO20590.1 - 2e-52 178.0 14.9 2.5e-52 177.7 14.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mesd PF10185.9 KDO20592.1 - 6.6e-08 32.6 1.3 4e-07 30.1 1.3 1.9 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF5069 PF16798.5 KDO20592.1 - 0.21 11.8 1.1 1.4 9.1 0.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF5069) DUF3073 PF11273.8 KDO20592.1 - 6.9 7.5 10.1 4.2 8.2 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3073) Lipase_GDSL_2 PF13472.6 KDO20593.1 - 6.3e-27 95.1 0.4 8.1e-27 94.8 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO20593.1 - 9.8e-20 71.4 0.0 1.2e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KDO20593.1 - 0.0034 17.1 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX Retrotrans_gag PF03732.17 KDO20594.1 - 2e-06 28.0 0.9 0.00022 21.5 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 KDO20594.1 - 0.00052 20.6 0.2 0.12 13.0 0.1 2.9 1 1 1 2 2 2 1 Aspartyl protease Phage_integrase PF00589.22 KDO20594.1 - 0.00069 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family gag-asp_proteas PF13975.6 KDO20594.1 - 0.015 15.9 0.2 5.4 7.6 0.1 3.7 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Ribonuc_red_lgN PF00317.21 KDO20594.1 - 0.069 13.2 0.4 9.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain zf-CCHC PF00098.23 KDO20594.1 - 0.077 13.1 3.6 0.26 11.5 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KDO20594.1 - 0.12 12.3 2.6 0.22 11.4 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle EGF_2 PF07974.13 KDO20596.1 - 4.2e-17 62.2 30.0 2.2e-06 27.9 3.8 4.8 4 1 0 4 4 4 4 EGF-like domain EGF PF00008.27 KDO20596.1 - 1.8e-05 24.9 43.5 0.0015 18.8 7.8 5.6 5 1 0 5 5 5 3 EGF-like domain hEGF PF12661.7 KDO20596.1 - 0.025 15.2 6.2 0.025 15.2 6.2 5.9 6 1 0 6 6 6 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 KDO20596.1 - 0.091 12.8 36.1 0.65 10.1 10.4 5.4 6 1 0 6 6 6 0 Tenascin EGF domain Laminin_EGF PF00053.24 KDO20596.1 - 0.29 11.3 34.0 0.43 10.8 11.6 4.0 3 3 0 3 3 3 0 Laminin EGF domain SKN1 PF03935.15 KDO20597.1 - 5.6e-07 28.3 0.0 8.1e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO20597.1 - 0.0033 17.7 2.8 0.0052 17.0 2.8 1.3 1 0 0 1 1 1 1 EB module Nodulin_late PF07127.11 KDO20597.1 - 0.081 13.3 1.2 0.15 12.4 1.2 1.4 1 0 0 1 1 1 0 Late nodulin protein T3SS_ATPase_C PF18269.1 KDO20597.1 - 0.26 11.1 0.3 16 5.4 0.0 2.2 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain EGF_2 PF07974.13 KDO20597.1 - 1.3 9.4 5.9 3.1 8.3 5.9 1.6 1 1 0 1 1 1 0 EGF-like domain Phage_int_SAM_1 PF02899.17 KDO20598.1 - 0.051 13.9 0.6 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain UDPGP PF01704.18 KDO20599.1 - 6.7e-122 407.1 0.0 6.5e-41 140.3 0.0 3.5 3 1 0 3 3 3 3 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KDO20599.1 - 9.5e-08 32.6 1.2 0.03 14.7 0.0 3.8 3 0 0 3 3 3 2 MobA-like NTP transferase domain Acetyltransf_19 PF18015.1 KDO20599.1 - 0.0034 17.6 0.0 8.2 6.7 0.0 3.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain RRM_4 PF10598.9 KDO20599.1 - 0.14 12.5 0.0 12 6.3 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif of the spliceosomal PrP8 TMEM251 PF15190.6 KDO20599.1 - 0.16 12.0 0.6 26 4.8 0.0 3.1 3 0 0 3 3 3 0 Transmembrane protein 251 Fez1 PF06818.15 KDO20600.1 - 0.015 15.8 1.9 0.015 15.8 1.9 1.9 1 1 0 2 2 2 0 Fez1 RT_RNaseH PF17917.1 KDO20600.1 - 0.053 13.8 0.3 0.075 13.3 0.3 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Prok-TraM PF09228.10 KDO20600.1 - 0.094 13.1 6.3 0.2 12.0 3.6 2.1 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Katanin_con80 PF13925.6 KDO20601.1 - 2.3 8.2 3.9 4.2 7.4 0.3 3.0 4 0 0 4 4 4 0 con80 domain of Katanin PTPlike_phytase PF14566.6 KDO20602.1 - 2.5e-79 264.8 0.4 5.3e-44 150.1 0.0 2.4 2 0 0 2 2 2 2 Inositol hexakisphosphate DSPc PF00782.20 KDO20602.1 - 0.00052 19.8 0.0 0.44 10.4 0.0 2.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO20602.1 - 0.00054 19.6 0.0 0.52 9.8 0.0 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KDO20602.1 - 0.046 13.7 0.1 2.7 7.9 0.0 2.6 3 0 0 3 3 3 0 Tyrosine phosphatase family GST_C_3 PF14497.6 KDO20604.1 - 8.5e-13 48.3 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO20604.1 - 5e-06 26.4 1.0 3.8e-05 23.6 1.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO20604.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO20604.1 - 0.0073 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO20605.1 - 2.2e-14 53.4 0.2 3.5e-14 52.8 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO20605.1 - 4.8e-05 23.6 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO20605.1 - 0.0012 19.1 0.1 0.0025 18.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO20605.1 - 0.011 15.7 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PWI PF01480.17 KDO20605.1 - 0.15 12.4 0.1 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 PWI domain FR47 PF08445.10 KDO20606.1 - 5.3e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KDO20606.1 - 8e-05 23.0 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO20606.1 - 0.00039 20.6 0.0 0.0006 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO20606.1 - 0.00082 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO20606.1 - 0.038 14.7 0.0 0.064 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GBP PF02263.19 KDO20609.1 - 4.1e-20 72.1 0.0 4.1e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Proteasome PF00227.26 KDO20611.1 - 1.8e-50 171.1 0.3 2.2e-50 170.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Prenyltrans PF00432.21 KDO20612.1 - 1.5e-59 197.4 17.1 5e-14 51.7 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KDO20612.1 - 2.7e-07 30.0 0.0 0.026 13.6 0.0 3.4 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KDO20612.1 - 5.7e-06 25.7 0.0 0.015 14.4 0.0 3.1 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SNAP PF14938.6 KDO20613.1 - 1.3e-97 326.6 24.7 1.5e-97 326.5 24.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KDO20613.1 - 2.2e-06 27.3 9.8 2.5 8.4 0.1 5.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20613.1 - 5.2e-06 26.2 15.1 2.7 8.3 1.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20613.1 - 4e-05 23.2 15.2 1 9.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20613.1 - 7.6e-05 22.9 12.6 0.072 13.4 0.9 3.9 1 1 4 5 5 5 4 Tetratricopeptide repeat MIT PF04212.18 KDO20613.1 - 0.0041 17.2 17.2 1.8 8.7 0.9 4.8 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KDO20613.1 - 0.03 14.5 14.2 13 6.4 0.0 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Pterin_4a PF01329.19 KDO20613.1 - 0.032 14.4 3.6 6.5 7.0 0.0 3.4 1 1 2 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase Foie-gras_1 PF11817.8 KDO20613.1 - 0.047 13.3 6.4 0.65 9.5 0.5 2.2 1 1 0 2 2 2 0 Foie gras liver health family 1 TPR_6 PF13174.6 KDO20613.1 - 0.075 13.7 12.9 12 6.7 0.2 5.5 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20613.1 - 0.094 13.4 8.2 6.4 7.5 0.4 4.4 1 1 3 4 4 4 0 Tetratricopeptide repeat Lar_restr_allev PF14354.6 KDO20613.1 - 1.1 9.7 4.8 2.6 8.5 2.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar PTS_IIA PF02255.16 KDO20613.1 - 9.2 6.4 14.4 3.2 7.9 0.2 4.0 2 1 2 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit Y_phosphatase2 PF03162.13 KDO20614.1 - 2.7e-33 114.9 0.0 3.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family CENP-P PF13096.6 KDO20614.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Ribosomal_S13 PF00416.22 KDO20615.1 - 7.8e-49 165.3 1.6 9.1e-49 165.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 KDO20615.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) FbpA PF05833.11 KDO20615.1 - 0.0044 15.9 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) BT1 PF03092.16 KDO20616.1 - 3.8e-83 279.5 16.3 9.7e-48 162.7 4.7 2.0 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO20616.1 - 2.7e-12 46.3 30.5 1e-11 44.4 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KDO20616.1 - 2.3e-06 26.9 3.3 2.3e-06 26.9 3.3 3.3 2 1 1 4 4 4 1 PUCC protein Acatn PF13000.7 KDO20616.1 - 0.2 10.1 10.6 3.5 6.0 6.0 3.1 2 1 1 3 3 3 0 Acetyl-coenzyme A transporter 1 PSII_Ycf12 PF05969.11 KDO20616.1 - 0.28 11.2 4.1 0.18 11.8 1.0 2.4 2 0 0 2 2 2 0 Photosystem II complex subunit Ycf12 FR47 PF08445.10 KDO20617.1 - 1.7e-07 31.1 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KDO20617.1 - 0.00029 21.2 0.0 0.00056 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO20617.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO20617.1 - 0.0014 18.9 0.0 0.0032 17.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KDO20617.1 - 0.021 15.5 0.0 0.05 14.3 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KDO20617.1 - 0.099 12.3 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO20618.1 - 4.3e-05 23.7 0.0 7.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO20618.1 - 0.00056 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO20618.1 - 0.0035 17.3 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KDO20618.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KDO20621.1 - 6.7e-96 321.9 20.3 8.5e-96 321.5 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO20621.1 - 3e-31 108.6 30.2 1.5e-21 76.7 12.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO20621.1 - 3e-07 29.3 1.8 3e-07 29.3 1.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ank_5 PF13857.6 KDO20622.1 - 1.3e-06 28.5 0.0 0.15 12.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20622.1 - 1.9e-06 28.3 0.0 0.83 10.3 0.0 3.2 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO20622.1 - 9.6e-05 22.5 0.3 11 6.9 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Aldedh PF00171.22 KDO20623.1 - 3.4e-42 144.5 2.7 9.3e-28 96.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family OmdA PF13376.6 KDO20623.1 - 0.099 12.7 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF1106 PF06523.11 KDO20624.1 - 0.069 13.2 0.1 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) F-box-like PF12937.7 KDO20625.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 KDO20627.1 - 2.5e-13 48.9 13.4 0.0014 18.5 0.1 6.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 KDO20627.1 - 0.04 13.7 6.8 0.31 10.9 0.0 4.1 4 2 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KDO20627.1 - 0.17 12.3 6.7 19 5.9 0.0 4.5 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) CRCB PF02537.15 KDO20628.1 - 0.0038 17.5 15.5 0.023 15.0 2.2 2.7 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) DUF2919 PF11143.8 KDO20628.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2919) Ank_2 PF12796.7 KDO20629.1 - 1.2e-29 102.8 7.6 2.3e-16 60.1 0.5 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20629.1 - 9.1e-21 74.0 9.2 5.4e-08 33.2 0.2 5.9 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20629.1 - 1.4e-20 71.2 8.5 0.00074 19.8 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KDO20629.1 - 1.4e-16 60.1 19.0 6.4e-06 26.4 0.1 7.2 5 2 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO20629.1 - 2.3e-14 53.3 15.9 0.00059 20.1 0.1 6.6 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ion_trans PF00520.31 KDO20629.1 - 2.4e-09 36.8 16.0 2.4e-09 36.8 16.0 2.3 2 0 0 2 2 2 1 Ion transport protein CBP_BcsF PF11120.8 KDO20629.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.9 4 0 0 4 4 4 0 Cellulose biosynthesis protein BcsF Peptidase_S10 PF00450.22 KDO20630.1 - 7.6e-119 397.8 0.5 9.6e-119 397.5 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KDO20630.1 - 0.0032 16.8 0.1 2.3 7.4 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DHHA2 PF02833.14 KDO20631.1 - 1.4e-12 48.0 0.0 5.2e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KDO20631.1 - 1.5e-06 28.3 0.6 3.1e-06 27.3 0.6 1.4 1 0 0 1 1 1 1 DHH family 5_3_exonuc_N PF02739.16 KDO20631.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HGD-D PF06050.13 KDO20631.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component WD40 PF00400.32 KDO20632.1 - 9.6e-33 111.7 24.5 9.7e-08 32.6 0.3 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat Bromodomain PF00439.25 KDO20632.1 - 1.2e-30 105.4 0.0 1.6e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain zf-HC5HC2H PF13771.6 KDO20632.1 - 1.4e-08 34.9 1.9 3.1e-08 33.7 1.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KDO20632.1 - 1.8e-06 28.1 2.0 4.5e-06 26.8 2.0 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain ANAPC4_WD40 PF12894.7 KDO20632.1 - 9.7e-05 22.6 0.0 13 6.1 0.0 5.4 2 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO20632.1 - 0.00037 19.5 0.1 0.99 8.3 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein C1_2 PF03107.16 KDO20632.1 - 0.24 11.8 2.2 0.68 10.3 2.2 1.8 1 0 0 1 1 1 0 C1 domain Peptidase_C69 PF03577.15 KDO20635.1 - 1.6e-28 99.7 0.0 1.6e-27 96.5 0.0 2.4 1 1 0 1 1 1 1 Peptidase family C69 Romo1 PF10247.9 KDO20635.1 - 0.021 15.2 0.5 0.043 14.2 0.5 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 YbgT_YccB PF08173.11 KDO20635.1 - 0.078 13.1 0.6 0.078 13.1 0.6 2.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Bap31 PF05529.12 KDO20637.1 - 1.3e-16 60.6 2.7 3e-16 59.5 2.7 1.6 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KDO20637.1 - 3e-07 30.3 18.9 1.9e-05 24.5 2.5 3.3 2 1 1 3 3 3 2 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 KDO20637.1 - 1e-05 25.7 9.7 0.12 12.6 0.7 3.7 3 1 0 3 3 3 2 Homeobox associated leucine zipper Med4 PF10018.9 KDO20637.1 - 3.2e-05 23.7 8.1 9.6e-05 22.1 8.1 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.15 KDO20637.1 - 6.9e-05 22.5 10.7 0.47 10.2 3.0 4.1 2 1 2 4 4 4 1 Septum formation initiator UPF0242 PF06785.11 KDO20637.1 - 8.4e-05 22.8 3.9 8.4e-05 22.8 3.9 1.6 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 KDO20637.1 - 0.00016 21.4 10.9 0.0028 17.3 5.3 2.0 1 1 1 2 2 2 2 Intermediate filament protein Cnn_1N PF07989.11 KDO20637.1 - 0.0066 16.6 10.5 0.85 9.8 0.3 3.0 1 1 1 3 3 3 2 Centrosomin N-terminal motif 1 TolA_bind_tri PF16331.5 KDO20637.1 - 0.0066 16.5 1.6 12 6.1 0.1 3.3 1 1 2 3 3 3 0 TolA binding protein trimerisation Lebercilin PF15619.6 KDO20637.1 - 0.0069 16.1 13.4 0.018 14.7 13.3 1.7 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.9 KDO20637.1 - 0.0071 16.6 13.9 0.23 11.8 0.3 2.6 2 1 1 3 3 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.12 KDO20637.1 - 0.0076 14.5 12.8 0.11 10.6 7.8 2.1 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA YabA PF06156.13 KDO20637.1 - 0.0093 16.6 7.3 0.3 11.7 3.2 2.6 2 1 0 2 2 2 1 Initiation control protein YabA APG6_N PF17675.1 KDO20637.1 - 0.01 16.3 17.0 1.2 9.6 17.1 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 KDO20637.1 - 0.012 15.9 1.0 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Fez1 PF06818.15 KDO20637.1 - 0.016 15.7 5.9 0.024 15.1 5.9 1.2 1 0 0 1 1 1 0 Fez1 ZapB PF06005.12 KDO20637.1 - 0.019 15.4 9.8 3.9 8.0 2.2 3.2 3 0 0 3 3 3 0 Cell division protein ZapB HBM PF16591.5 KDO20637.1 - 0.021 14.3 8.4 0.033 13.6 8.4 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain GAS PF13851.6 KDO20637.1 - 0.022 14.1 15.3 0.15 11.4 15.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KDO20637.1 - 0.025 13.5 16.5 0.096 11.6 10.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KDO20637.1 - 0.026 14.9 7.0 0.43 11.0 0.5 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KDO20637.1 - 0.026 14.8 13.7 1 9.5 12.1 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF5595 PF18077.1 KDO20637.1 - 0.027 14.6 1.8 0.057 13.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) bZIP_1 PF00170.21 KDO20637.1 - 0.038 14.1 10.8 1.6 8.9 0.1 3.4 3 1 0 3 3 3 0 bZIP transcription factor DUF3734 PF12536.8 KDO20637.1 - 0.042 14.2 0.7 0.089 13.1 0.7 1.6 1 0 0 1 1 1 0 Patatin phospholipase BBP1_C PF15272.6 KDO20637.1 - 0.074 12.9 9.0 0.13 12.1 9.0 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DivIVA PF05103.13 KDO20637.1 - 0.09 12.9 14.6 0.49 10.5 13.7 2.3 1 1 1 2 2 2 0 DivIVA protein Cauli_AT PF03233.13 KDO20637.1 - 0.093 12.7 0.5 0.093 12.7 0.5 2.1 1 1 1 2 2 2 0 Aphid transmission protein Csm1_N PF18504.1 KDO20637.1 - 0.11 12.8 11.9 2.2 8.7 2.7 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain Ax_dynein_light PF10211.9 KDO20637.1 - 0.12 12.3 11.1 0.97 9.4 5.4 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DUF724 PF05266.14 KDO20637.1 - 0.15 11.9 11.3 0.24 11.2 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.11 KDO20637.1 - 0.16 11.8 19.3 1.4 8.8 1.9 3.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 JIP_LZII PF16471.5 KDO20637.1 - 0.16 12.1 7.1 5.3 7.3 0.1 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 KDO20637.1 - 0.18 11.9 6.8 3.1 7.9 0.3 3.2 3 1 0 3 3 3 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KDO20637.1 - 0.18 11.9 20.4 0.39 10.8 14.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.16 KDO20637.1 - 0.19 12.0 7.8 3.8 7.7 3.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein TMF_TATA_bd PF12325.8 KDO20637.1 - 0.23 11.7 11.2 3.1 8.0 6.9 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4600 PF15372.6 KDO20637.1 - 0.3 11.5 10.8 0.12 12.8 5.7 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) PRKG1_interact PF15898.5 KDO20637.1 - 0.38 11.7 13.2 0.14 13.1 7.9 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 KDO20637.1 - 0.38 10.8 13.3 1.5 8.8 9.7 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 KDO20637.1 - 0.4 9.9 2.7 0.61 9.4 2.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GIT_CC PF16559.5 KDO20637.1 - 0.46 10.4 12.0 0.99 9.3 0.5 3.6 1 1 3 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DHR10 PF18595.1 KDO20637.1 - 0.49 10.5 14.5 2.9 8.0 0.8 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain GrpE PF01025.19 KDO20637.1 - 0.5 10.0 16.5 0.13 11.9 3.6 3.0 1 1 2 3 3 3 0 GrpE WXG100 PF06013.12 KDO20637.1 - 0.56 10.5 8.6 0.37 11.0 3.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG K-box PF01486.17 KDO20637.1 - 0.6 10.3 7.0 24 5.2 7.0 2.5 1 1 0 1 1 1 0 K-box region Prefoldin PF02996.17 KDO20637.1 - 0.64 9.9 12.9 0.52 10.2 0.4 3.1 1 1 1 3 3 3 0 Prefoldin subunit DUF2205 PF10224.9 KDO20637.1 - 0.68 10.0 7.0 1.7 8.7 0.3 3.1 3 0 0 3 3 3 0 Short coiled-coil protein DUF465 PF04325.13 KDO20637.1 - 0.75 9.9 8.4 25 5.0 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Baculo_PEP_C PF04513.12 KDO20637.1 - 0.77 9.8 6.0 1.4 9.0 5.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CwsA PF10814.8 KDO20637.1 - 0.84 9.8 3.5 1.2 9.3 2.6 1.7 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA DUF3450 PF11932.8 KDO20637.1 - 0.86 8.9 12.8 3.6 6.8 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KDO20637.1 - 0.87 8.9 15.7 1.1 8.6 14.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KDO20637.1 - 0.9 9.6 12.8 0.87 9.6 4.6 2.4 1 1 1 2 2 2 0 FlxA-like protein Cep57_CLD_2 PF14197.6 KDO20637.1 - 1.1 9.4 10.9 5.8 7.1 0.2 3.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 KDO20637.1 - 1.2 9.2 21.6 0.86 9.6 5.5 3.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 KDO20637.1 - 1.2 9.4 15.6 12 6.2 13.2 2.7 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Lzipper-MIP1 PF14389.6 KDO20637.1 - 1.3 9.4 6.8 1.1 9.6 4.0 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.20 KDO20637.1 - 1.4 8.9 14.4 2.1 8.3 2.8 3.2 2 1 1 3 3 3 0 Prefoldin subunit DUF812 PF05667.11 KDO20637.1 - 1.5 7.6 13.5 2.8 6.7 13.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4140 PF13600.6 KDO20637.1 - 1.7 9.1 13.4 1.8 9.0 2.1 3.0 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Jnk-SapK_ap_N PF09744.9 KDO20637.1 - 1.7 8.9 13.2 0.73 10.0 8.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SOGA PF11365.8 KDO20637.1 - 1.8 9.8 8.7 1.4 10.1 4.5 2.4 1 1 2 3 3 3 0 Protein SOGA kleA_kleC PF17383.2 KDO20637.1 - 1.9 8.9 5.2 3 8.2 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DUF4200 PF13863.6 KDO20637.1 - 2 8.8 14.6 3.7 8.0 8.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.13 KDO20637.1 - 3.1 8.6 7.3 5.8 7.7 2.6 2.8 1 1 1 2 2 2 0 Occludin homology domain JAKMIP_CC3 PF16034.5 KDO20637.1 - 3.7 7.5 11.1 1.7e+02 2.0 11.1 2.8 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF1664 PF07889.12 KDO20637.1 - 3.8 7.6 7.4 4.8 7.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 KDO20637.1 - 4.5 7.4 12.4 24 5.1 3.0 3.2 2 1 0 3 3 3 0 Swi5 zf-C4H2 PF10146.9 KDO20637.1 - 4.6 7.5 6.8 7.2 6.9 6.8 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein She9_MDM33 PF05546.11 KDO20637.1 - 4.9 6.9 10.1 4.8 6.9 4.7 2.7 1 1 1 2 2 2 0 She9 / Mdm33 family FapA PF03961.13 KDO20637.1 - 5.2 5.6 10.6 6.4 5.3 9.1 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 KDO20637.1 - 5.4 7.2 8.4 16 5.7 8.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 KDO20637.1 - 6.6 7.3 11.0 1.4e+02 3.1 6.6 3.0 1 1 1 2 2 2 0 Spectrin repeat ADIP PF11559.8 KDO20637.1 - 7.5 6.6 14.9 20 5.3 0.6 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.11 KDO20637.1 - 7.6 6.9 13.7 2 8.7 6.5 3.2 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) PCRF PF03462.18 KDO20637.1 - 8.1 6.3 11.5 5.4 6.8 7.4 2.0 1 1 1 2 2 2 0 PCRF domain Spc24 PF08286.11 KDO20637.1 - 10 6.5 14.9 10 6.5 0.6 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Lectin_leg-like PF03388.13 KDO20638.1 - 2.2e-30 105.7 0.0 3.6e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KDO20638.1 - 1.1e-12 48.3 0.8 1.1e-12 48.3 0.8 1.5 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 KDO20638.1 - 2e-06 27.5 0.0 5.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Legume lectin domain RRP36 PF06102.12 KDO20638.1 - 0.0077 16.2 1.4 0.012 15.5 1.4 1.2 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF1690 PF07956.11 KDO20638.1 - 0.18 12.2 4.5 0.1 13.1 1.6 1.8 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) CLZ PF16526.5 KDO20638.1 - 0.32 11.4 3.9 2.6 8.5 1.2 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 KDO20638.1 - 9.4 6.3 9.0 0.37 10.8 2.2 2.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding RNA_lig_T4_1 PF09511.10 KDO20640.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DUF4823 PF16105.5 KDO20640.1 - 0.016 15.1 0.2 0.52 10.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4823) SSL_OB PF09199.10 KDO20640.1 - 0.029 14.7 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain Ank_2 PF12796.7 KDO20641.1 - 7.2e-11 42.5 5.6 5.2e-05 23.8 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20641.1 - 6.7e-08 32.9 10.3 0.15 12.7 0.1 5.1 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20641.1 - 5.1e-07 29.8 6.9 1.1 9.7 0.0 5.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20641.1 - 3.1e-05 24.0 3.7 1.8 9.3 0.0 6.1 6 1 1 7 7 7 1 Ankyrin repeat Phage_int_SAM_1 PF02899.17 KDO20641.1 - 0.019 15.2 0.8 1.2 9.5 0.1 3.3 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain Ank PF00023.30 KDO20641.1 - 0.037 14.5 3.4 13 6.4 1.1 5.1 2 1 0 2 2 2 0 Ankyrin repeat Cuticle_4 PF15955.5 KDO20641.1 - 0.88 10.3 5.5 0.17 12.6 1.1 2.1 2 1 0 2 2 2 0 Cuticle protein YjbE PF11106.8 KDO20642.1 - 0.028 14.6 10.8 0.042 14.1 10.8 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE UPF0004 PF00919.20 KDO20642.1 - 0.066 13.3 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF4690 PF15756.5 KDO20642.1 - 0.12 13.0 3.3 0.14 12.8 3.0 1.4 1 1 0 1 1 1 0 Small Novel Rich in Cartilage DUF2613 PF11021.8 KDO20642.1 - 0.91 9.7 6.1 0.22 11.6 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Pilosulin PF17499.2 KDO20642.1 - 2 8.6 6.0 4.9 7.4 6.0 1.7 1 1 0 1 1 1 0 Ant venom peptides CLASP_N PF12348.8 KDO20643.1 - 8.5e-06 25.5 0.7 1.9e-05 24.4 0.3 1.7 1 1 1 2 2 2 1 CLASP N terminal SLC12 PF03522.15 KDO20644.1 - 9.4e-36 123.8 1.9 3.6e-13 49.4 0.0 3.3 3 1 1 4 4 4 3 Solute carrier family 12 AA_permease PF00324.21 KDO20644.1 - 6.5e-17 61.3 4.2 9.7e-17 60.7 4.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO20644.1 - 0.022 13.6 7.5 0.036 12.9 7.5 1.3 1 0 0 1 1 1 0 Amino acid permease AA_permease PF00324.21 KDO20645.1 - 6.5e-13 48.1 15.7 7.6e-13 47.9 15.7 1.1 1 0 0 1 1 1 1 Amino acid permease Nairovirus_M PF07948.11 KDO20645.1 - 0.052 11.8 1.2 0.071 11.3 1.2 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like TcpS PF17456.2 KDO20646.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S PK PF00224.21 KDO20647.1 - 1.1e-127 425.7 2.1 1.6e-127 425.2 0.6 1.8 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KDO20647.1 - 8.2e-23 80.9 0.9 2.2e-22 79.5 0.9 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KDO20647.1 - 0.0036 16.5 0.1 0.016 14.3 0.0 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF3829 PF12889.7 KDO20647.1 - 0.012 15.1 0.2 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) PAS PF00989.25 KDO20648.1 - 0.039 13.9 0.4 0.071 13.1 0.1 1.6 2 0 0 2 2 2 0 PAS fold AAA PF00004.29 KDO20649.1 - 3.5e-43 147.2 0.0 6.8e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO20649.1 - 3.2e-09 36.4 0.0 7.3e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KDO20649.1 - 2.6e-07 31.2 0.6 0.00012 22.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KDO20649.1 - 2.2e-06 27.7 0.0 6.2e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO20649.1 - 5.1e-06 26.8 0.6 0.0002 21.6 0.6 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KDO20649.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KDO20649.1 - 5.8e-05 22.4 0.0 0.00013 21.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KDO20649.1 - 0.00027 21.1 0.0 0.00067 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KDO20649.1 - 0.00032 20.5 0.0 0.00087 19.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KDO20649.1 - 0.00041 20.0 2.0 0.6 9.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KDO20649.1 - 0.00056 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KDO20649.1 - 0.00097 18.7 0.0 0.0034 16.9 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KDO20649.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 KDO20649.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KDO20649.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KDO20649.1 - 0.017 15.7 0.0 0.037 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO20649.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KDO20649.1 - 0.025 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KDO20649.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KDO20649.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO20649.1 - 0.094 12.4 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KDO20649.1 - 0.12 12.1 0.1 0.36 10.5 0.1 1.8 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 KDO20649.1 - 0.13 12.2 0.2 0.58 10.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KDO20649.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CrgA PF06781.12 KDO20650.1 - 0.0091 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Cell division protein CrgA RAMP PF04901.13 KDO20650.1 - 0.028 14.4 0.1 0.064 13.3 0.1 1.6 1 0 0 1 1 1 0 Receptor activity modifying family Syndecan PF01034.20 KDO20650.1 - 0.31 11.0 1.1 0.57 10.1 1.1 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM52 PF14979.6 KDO20651.1 - 0.081 12.8 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Transmembrane 52 GT87 PF09594.10 KDO20652.1 - 0.043 13.5 0.9 0.057 13.1 0.9 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 OppC_N PF12911.7 KDO20652.1 - 1.4 9.0 4.0 2.2 8.3 0.0 2.6 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C WD40 PF00400.32 KDO20653.1 - 7.2e-12 45.6 8.0 0.022 15.6 0.8 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20653.1 - 9.9e-06 25.8 0.0 0.45 10.9 0.0 4.7 1 1 5 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KDO20653.1 - 0.019 15.5 1.8 0.76 10.4 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain PmrD PF11183.8 KDO20655.1 - 0.094 12.8 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD YIEGIA PF14045.6 KDO20655.1 - 0.098 11.5 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 YIEGIA protein zf-RAG1 PF10426.9 KDO20657.1 - 0.23 11.6 5.6 16 5.8 0.1 3.6 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain PAS PF00989.25 KDO20659.1 - 0.19 11.7 0.3 0.32 11.0 0.3 1.3 1 0 0 1 1 1 0 PAS fold RICTOR_N PF14664.6 KDO20660.1 - 3.8e-79 266.4 1.5 6.7e-79 265.6 1.5 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 KDO20660.1 - 5.8e-25 87.3 1.1 4e-22 78.2 0.1 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 KDO20660.1 - 9.1e-25 86.4 0.6 9.4e-24 83.2 0.3 3.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KDO20660.1 - 4.8e-20 72.0 1.2 5.8e-19 68.5 0.2 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 KDO20660.1 - 0.025 15.1 0.2 8.5 7.0 0.1 3.2 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 KDO20660.1 - 4.6 7.4 13.6 66 3.7 0.1 6.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Lpp-LpqN PF10738.9 KDO20661.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN EF-hand_8 PF13833.6 KDO20663.1 - 0.0029 17.4 0.1 0.29 11.0 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO20663.1 - 0.021 15.3 0.2 8.7 6.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 KDO20663.1 - 0.19 11.7 0.3 9.7 6.4 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain NUFIP1 PF10453.9 KDO20664.1 - 2e-12 46.7 3.1 3.7e-12 45.9 3.1 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KDO20664.1 - 2e-09 37.1 4.3 1.6e-06 27.9 1.5 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO20664.1 - 4.8e-08 32.8 10.3 4.1e-05 23.5 3.8 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KDO20664.1 - 6.3e-06 26.9 8.9 0.0025 18.5 1.1 3.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KDO20664.1 - 3.8e-05 23.4 10.1 0.0012 18.6 1.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KDO20664.1 - 0.002 18.3 0.8 0.0053 17.0 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCHC_3 PF13917.6 KDO20664.1 - 0.0034 17.3 0.1 0.0078 16.2 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 KDO20664.1 - 0.035 14.4 1.2 0.08 13.3 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-CCHC PF00098.23 KDO20664.1 - 0.09 12.9 2.9 0.27 11.4 2.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Ank_4 PF13637.6 KDO20665.1 - 4e-15 56.0 5.0 0.00013 22.5 0.2 4.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20665.1 - 4.1e-15 56.1 0.9 5.8e-08 33.2 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20665.1 - 1.6e-10 41.0 7.1 0.0046 17.2 0.0 5.5 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20665.1 - 2e-09 36.9 4.8 4.6 8.1 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 KDO20665.1 - 0.00061 19.6 0.1 28 4.7 0.0 4.8 3 2 2 5 5 5 0 Domain of unknown function (DUF5049) Ank PF00023.30 KDO20665.1 - 0.042 14.3 1.3 40 4.9 0.0 4.4 2 2 1 3 3 3 0 Ankyrin repeat YmaF PF12788.7 KDO20665.1 - 1.5 9.4 5.5 4.5 7.9 0.1 3.3 2 2 2 4 4 4 0 YmaF family RabGAP-TBC PF00566.18 KDO20666.1 - 7.4e-40 136.9 0.0 9.1e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AAA_lid_8 PF17868.1 KDO20667.1 - 0.087 12.7 0.5 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA lid domain Pro_isomerase PF00160.21 KDO20668.1 - 1.4e-33 116.4 0.0 2.3e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KDO20668.1 - 9.5e-12 44.6 0.1 2.3e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 KDO20670.1 - 8.9e-08 32.1 11.6 9.5e-06 25.6 2.8 2.6 2 0 0 2 2 2 2 WW domain Ank_3 PF13606.6 KDO20670.1 - 1.3e-07 31.4 0.7 0.00041 20.6 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO20670.1 - 2.2e-07 31.3 0.7 6.5e-07 29.8 0.7 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20670.1 - 5.2e-06 26.6 1.2 8.2e-05 22.8 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20670.1 - 6.2e-06 26.7 2.3 7.2e-05 23.3 0.9 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO20670.1 - 5.8e-05 23.4 1.5 0.00046 20.5 0.3 2.7 2 0 0 2 2 2 1 Ankyrin repeat IQ PF00612.27 KDO20670.1 - 0.005 16.5 0.9 0.005 16.5 0.9 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Glycos_transf_2 PF00535.26 KDO20671.1 - 1.2e-18 67.5 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KDO20671.1 - 2.8e-09 37.2 0.0 3.9e-09 36.7 0.0 1.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 KDO20671.1 - 0.041 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF2606 PF10794.9 KDO20671.1 - 0.13 12.1 0.0 9.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2606) TPR_1 PF00515.28 KDO20672.1 - 6.6e-25 85.9 6.9 5.7e-07 29.1 1.2 5.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20672.1 - 3.9e-24 82.8 9.7 8.5e-07 28.6 1.4 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20672.1 - 4.4e-21 75.2 6.9 1.4e-10 41.6 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20672.1 - 2.8e-20 71.3 7.6 0.00025 21.6 0.1 7.3 4 2 4 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20672.1 - 3.5e-19 69.2 1.0 1e-06 29.2 0.0 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20672.1 - 2.1e-17 61.8 2.1 0.00027 20.9 0.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20672.1 - 7.6e-17 60.7 10.8 4.1e-05 23.2 0.0 5.6 4 2 2 6 6 6 5 TPR repeat TPR_17 PF13431.6 KDO20672.1 - 1.5e-14 53.3 7.2 0.0013 19.0 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20672.1 - 1.9e-12 46.3 4.2 0.00014 21.6 0.5 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO20672.1 - 3.7e-12 46.2 3.0 4.9e-05 23.4 0.1 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20672.1 - 2.2e-10 40.7 5.8 0.00023 21.4 0.8 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 KDO20672.1 - 1.1e-08 35.2 0.0 1 10.1 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 KDO20672.1 - 0.00047 20.4 2.5 0.12 12.8 0.1 4.5 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20672.1 - 0.0011 18.8 3.1 0.077 12.9 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO20672.1 - 0.0019 18.4 4.9 0.022 15.0 0.1 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KDO20672.1 - 0.017 15.2 0.9 2.7 8.2 0.2 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain C2 PF00168.30 KDO20674.1 - 3.4e-96 316.4 0.0 1.8e-15 57.1 0.0 8.2 8 0 0 8 8 8 7 C2 domain FerI PF08151.12 KDO20674.1 - 8.3e-06 25.8 0.1 2.6e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 FerI (NUC094) domain U3_snoRNA_assoc PF08297.11 KDO20674.1 - 0.17 12.6 0.8 0.49 11.1 0.8 1.7 1 0 0 1 1 1 0 U3 snoRNA associated Pribosyltran PF00156.27 KDO20675.1 - 3.5e-23 81.9 0.0 4.4e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KDO20675.1 - 0.04 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 KDO20675.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.4 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase BolA PF01722.18 KDO20676.1 - 2.6e-17 62.8 0.0 8.3e-17 61.2 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Kinesin PF00225.23 KDO20679.1 - 9.6e-114 379.8 1.8 1.7e-113 379.0 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO20679.1 - 3.2e-28 98.6 0.0 2.2e-26 92.6 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding HOOK PF05622.12 KDO20679.1 - 0.0011 17.2 36.3 0.0011 17.2 36.3 2.7 1 1 1 2 2 2 1 HOOK protein Coatomer_WDAD PF04053.14 KDO20681.1 - 2.8e-146 488.1 0.0 4e-146 487.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KDO20681.1 - 3.6e-13 49.7 5.4 3.4e-07 30.9 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 KDO20681.1 - 0.052 13.4 0.0 18 5.1 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TBCA PF02970.16 KDO20682.1 - 5.1e-22 78.0 3.6 5.8e-22 77.8 3.6 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A TAP42 PF04177.12 KDO20682.1 - 0.00081 18.6 1.7 0.00087 18.5 1.7 1.1 1 0 0 1 1 1 1 TAP42-like family Staph_opine_DH PF10100.9 KDO20682.1 - 0.026 13.2 0.1 0.029 13.0 0.1 1.0 1 0 0 1 1 1 0 Staphylopine dehydrogenase MDH PF02315.16 KDO20682.1 - 0.1 12.6 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit TIL PF01826.17 KDO20683.1 - 6.1 7.2 14.0 1.2 9.5 7.5 2.3 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain zf-BED PF02892.15 KDO20684.1 - 4.3e-09 36.2 0.6 8.4e-09 35.3 0.6 1.5 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 KDO20684.1 - 0.033 14.0 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-H2C2_5 PF13909.6 KDO20684.1 - 0.15 11.8 0.3 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain WD40 PF00400.32 KDO20685.1 - 9.6e-16 57.9 0.3 0.00079 20.2 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO20685.1 - 0.005 17.1 0.1 0.05 13.9 0.0 2.2 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO20685.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 1 1 2 2 2 0 WD40-like domain CBM_1 PF00734.18 KDO20687.1 - 8.7e-11 41.6 6.5 2e-10 40.5 6.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO20687.1 - 0.00023 20.6 68.5 0.0012 18.4 23.6 3.7 1 1 1 2 2 2 1 PT repeat Neisseria_TspB PF05616.13 KDO20687.1 - 5 5.5 14.1 5.5 5.4 14.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Globin PF00042.22 KDO20689.1 - 0.011 16.3 0.4 0.23 12.0 0.4 2.3 1 1 0 1 1 1 0 Globin RRM_1 PF00076.22 KDO20690.1 - 5.5e-42 141.5 0.0 6.5e-15 54.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO20690.1 - 2.1e-06 27.8 0.1 0.042 14.0 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO20690.1 - 0.0077 16.2 0.0 0.09 12.8 0.0 2.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KDO20690.1 - 0.014 15.0 0.2 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_3 PF08777.11 KDO20690.1 - 0.14 12.2 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif His_Phos_2 PF00328.22 KDO20691.1 - 1.4e-18 67.4 0.0 3.1e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KDO20693.1 - 1.9e-15 57.1 0.0 5e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KDO20694.1 - 3.4e-14 53.0 0.1 3.4e-06 26.7 0.0 2.6 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) GST_N_3 PF13417.6 KDO20695.1 - 1e-12 48.3 0.1 2.1e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KDO20695.1 - 5.4e-11 42.5 3.3 1.1e-10 41.5 3.3 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KDO20695.1 - 3.2e-08 33.8 0.0 6.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO20695.1 - 6.9e-06 26.3 0.1 1.6e-05 25.1 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KDO20695.1 - 0.00013 21.7 0.0 0.00037 20.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO20695.1 - 0.00055 19.9 0.1 0.0013 18.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KDO20695.1 - 0.00079 20.1 0.0 0.002 18.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 KDO20695.1 - 0.029 14.6 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin_3 PF13192.6 KDO20695.1 - 0.09 12.8 1.8 0.21 11.7 1.8 1.5 1 0 0 1 1 1 0 Thioredoxin domain GATase_5 PF13507.6 KDO20696.1 - 8e-93 310.3 0.0 1.1e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KDO20696.1 - 1.2e-32 113.2 4.5 1.5e-17 64.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KDO20696.1 - 9.6e-21 73.9 0.0 1.7e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KDO20696.1 - 2.2e-10 40.9 0.0 5.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KDO20696.1 - 0.006 17.2 1.5 0.11 13.2 0.0 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain F_actin_cap_B PF01115.17 KDO20697.1 - 8.5e-95 316.9 0.0 9.7e-95 316.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KDO20697.1 - 0.00094 18.7 0.0 0.003 17.0 0.0 1.7 1 1 0 1 1 1 1 F-actin capping protein alpha subunit N_formyltrans_C PF18216.1 KDO20697.1 - 0.0059 16.3 0.0 0.088 12.5 0.0 2.7 3 0 0 3 3 3 1 N-formyltransferase dimerization C-terminal domain Pkinase PF00069.25 KDO20698.1 - 9e-37 126.9 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20698.1 - 1.6e-33 116.1 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO20698.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat EphA2_TM PF14575.6 KDO20698.1 - 0.13 13.2 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 KDO20698.1 - 0.69 10.3 2.2 1.3 9.5 2.2 1.3 1 0 0 1 1 1 0 FAM163 family Adeno_E3_CR2 PF02439.15 KDO20698.1 - 2.6 7.9 8.4 0.91 9.3 5.2 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 KDO20699.1 - 1.5e-46 158.9 0.0 2.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20699.1 - 9.5e-45 152.9 0.0 1.3e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO20699.1 - 2.6e-11 43.1 13.5 0.0017 18.1 2.3 4.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KDO20699.1 - 4.7e-06 26.2 6.5 0.00019 21.0 0.7 2.7 2 1 0 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KDO20699.1 - 0.00043 20.6 29.9 0.31 11.5 0.6 5.7 3 2 3 7 7 7 4 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO20699.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO20699.1 - 0.0079 16.1 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gram_pos_anchor PF00746.21 KDO20699.1 - 0.0098 15.8 0.4 0.029 14.3 0.4 1.8 1 0 0 1 1 1 1 LPXTG cell wall anchor motif LPG_synthase_TM PF03706.13 KDO20699.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Haspin_kinase PF12330.8 KDO20699.1 - 0.2 10.6 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LRR_6 PF13516.6 KDO20699.1 - 0.27 11.4 5.6 18 5.7 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat FNIP PF05725.12 KDO20699.1 - 0.54 10.5 2.9 24 5.2 0.8 3.6 3 1 1 4 4 4 0 FNIP Repeat LRR_1 PF00560.33 KDO20699.1 - 4.7 8.1 10.5 1.8e+02 3.3 1.7 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat Transket_pyr PF02779.24 KDO20700.1 - 2.2e-63 213.2 0.0 3.1e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KDO20700.1 - 1.1e-59 201.9 0.0 1.5e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KDO20700.1 - 6.6e-48 162.3 0.0 1.3e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KDO20700.1 - 1.3e-18 66.3 0.5 2.9e-18 65.2 0.5 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 KDO20700.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 EF-hand_6 PF13405.6 KDO20701.1 - 9.6e-13 47.0 12.7 0.043 13.8 0.7 8.5 8 1 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 KDO20701.1 - 8.7e-11 42.1 7.0 0.35 11.3 0.0 7.5 6 2 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO20701.1 - 1.4e-09 36.8 5.1 0.035 13.7 0.1 6.8 7 0 0 7 7 7 3 EF hand DUF5580 PF17743.1 KDO20701.1 - 6.7e-06 24.9 0.0 0.02 13.4 0.0 2.7 2 1 1 3 3 3 2 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 KDO20701.1 - 0.0068 15.9 0.6 0.14 11.7 0.3 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KDO20701.1 - 0.013 15.3 1.2 3.5 7.6 0.0 4.7 5 0 0 5 5 5 0 EF-hand domain pair RST PF12174.8 KDO20701.1 - 0.026 14.4 7.1 3.7 7.6 0.1 5.2 7 0 0 7 7 7 0 RCD1-SRO-TAF4 (RST) plant domain TTL PF03133.15 KDO20703.1 - 2.2e-100 335.6 0.2 3e-100 335.1 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO20703.1 - 7.1e-08 32.0 0.1 4.6e-05 22.8 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO20703.1 - 5.1e-05 22.7 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 KDO20703.1 - 0.073 12.7 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Myb_DNA-binding PF00249.31 KDO20704.1 - 1.4e-07 31.6 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20704.1 - 0.00038 20.6 0.2 0.00044 20.5 0.2 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO20704.1 - 0.013 15.3 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Myb DNA-binding like FUSC PF04632.12 KDO20704.1 - 0.21 10.1 0.7 0.24 9.9 0.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family AMP-binding PF00501.28 KDO20705.1 - 7.3e-10 38.0 0.2 1.1e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thump_like PF18096.1 KDO20705.1 - 0.044 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 THUMP domain-like FLYWCH_u PF16662.5 KDO20705.1 - 0.045 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 Acyl-CoA_dh_1 PF00441.24 KDO20706.1 - 1.6e-34 119.3 1.0 2.7e-34 118.6 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KDO20706.1 - 3.6e-31 108.2 0.0 6.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KDO20706.1 - 1.1e-14 54.9 0.4 3.2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KDO20706.1 - 1.6e-12 47.4 0.6 3.7e-11 43.1 0.3 2.4 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KDO20706.1 - 0.032 14.8 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal NAD_synthase PF02540.17 KDO20707.1 - 3.1e-07 29.7 0.0 1.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 KDO20707.1 - 2e-06 26.8 0.0 0.0007 18.5 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 KDO20707.1 - 3.8e-05 23.3 0.0 0.069 12.6 0.0 2.5 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KDO20707.1 - 0.00026 20.8 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 KDO20707.1 - 0.019 14.7 0.0 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.19 KDO20707.1 - 0.039 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 KDO20707.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family N2227 PF07942.12 KDO20709.1 - 3e-79 266.0 0.0 3.8e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KDO20709.1 - 0.0024 18.6 0.0 0.0048 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO20709.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO20709.1 - 0.07 13.8 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Rad21_Rec8_N PF04825.13 KDO20711.1 - 1.4e-36 125.0 0.0 2.9e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KDO20711.1 - 3.6e-12 45.4 1.2 6.1e-11 41.4 0.1 2.6 3 0 0 3 3 3 1 Conserved region of Rad21 / Rec8 like protein Fumble PF03630.14 KDO20712.1 - 1.1e-92 310.8 0.1 1.3e-92 310.5 0.1 1.0 1 0 0 1 1 1 1 Fumble Cnn_1N PF07989.11 KDO20713.1 - 3.6e-10 39.9 8.0 3.6e-10 39.9 8.0 10.0 5 3 5 10 10 10 3 Centrosomin N-terminal motif 1 Actin PF00022.19 KDO20714.1 - 4e-50 170.6 0.0 8e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 Actin SurA_N_2 PF13623.6 KDO20714.1 - 0.047 13.6 2.3 0.3 10.9 2.3 2.4 1 0 0 1 1 1 0 SurA N-terminal domain Beach PF02138.18 KDO20715.1 - 3.6e-99 331.6 0.0 2.2e-54 184.7 0.0 2.3 1 1 1 2 2 2 2 Beige/BEACH domain PH_BEACH PF14844.6 KDO20715.1 - 3.5e-06 27.0 0.0 6.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KDO20715.1 - 3.7e-06 27.6 5.6 1.4 9.9 0.0 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 KDO20715.1 - 1.6e-05 25.1 0.3 0.00012 22.2 0.0 2.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Metallophos PF00149.28 KDO20716.1 - 2.1e-12 48.0 0.3 4.1e-12 47.0 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO20716.1 - 0.0021 18.3 0.2 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SGP PF17228.2 KDO20716.1 - 0.49 11.3 3.7 0.37 11.7 1.7 1.7 2 0 0 2 2 2 0 Sulphur globule protein COMM_domain PF07258.14 KDO20717.1 - 1.6e-12 47.3 0.1 2.5e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 COMM domain Aminotran_5 PF00266.19 KDO20718.1 - 1.5e-30 106.4 0.0 1.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF29 PF01724.16 KDO20719.1 - 0.019 15.2 2.0 0.037 14.2 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 5_nucleotid PF05761.14 KDO20719.1 - 0.26 10.1 1.0 0.35 9.7 1.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Prefoldin PF02996.17 KDO20727.1 - 2.2e-27 95.4 0.2 3.1e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF5082 PF16888.5 KDO20727.1 - 0.00044 20.5 1.1 0.018 15.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 KDO20727.1 - 0.013 16.1 5.0 0.11 13.1 0.2 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_2 PF01920.20 KDO20727.1 - 0.018 15.0 7.9 0.033 14.2 1.5 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF4510 PF14971.6 KDO20727.1 - 0.047 14.0 0.6 1.8 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) ApoO PF09769.9 KDO20727.1 - 0.056 13.4 0.3 13 5.7 0.0 2.9 2 1 1 3 3 3 0 Apolipoprotein O SlyX PF04102.12 KDO20727.1 - 3.2 8.4 5.6 1.6 9.4 0.9 2.2 2 0 0 2 2 2 0 SlyX Rab5ip PF07019.12 KDO20728.1 - 4.9e-14 52.7 9.1 5.8e-14 52.4 9.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Myb_DNA-binding PF00249.31 KDO20729.1 - 3.3e-09 36.8 0.2 5.1e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20729.1 - 0.075 13.3 0.2 0.098 12.9 0.2 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO20730.1 - 1.1e-10 41.5 0.1 1.4e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO20731.1 - 2.4e-09 37.2 0.2 3.6e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20731.1 - 0.072 13.3 0.3 0.1 12.9 0.3 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Metallophos PF00149.28 KDO20732.1 - 3.1e-09 37.7 0.1 5.1e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO20732.1 - 5.5e-05 23.4 0.0 0.00092 19.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SurE PF01975.17 KDO20732.1 - 0.041 13.6 0.1 0.073 12.8 0.1 1.4 1 1 0 1 1 1 0 Survival protein SurE Adaptin_binding PF10199.9 KDO20733.1 - 8.5e-12 45.8 1.8 5.2e-11 43.2 1.8 2.0 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Diphthami_syn_2 PF01902.17 KDO20734.1 - 1.9e-34 119.1 0.0 2.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase Ank_2 PF12796.7 KDO20735.1 - 2.9e-15 56.6 11.8 3e-05 24.5 0.1 3.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20735.1 - 7.3e-14 51.9 13.7 0.00012 22.5 0.5 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20735.1 - 3.5e-06 27.2 12.6 0.14 12.5 0.1 6.2 2 1 5 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20735.1 - 0.00019 21.6 9.4 20 6.2 0.1 6.4 4 2 3 7 7 7 1 Ankyrin repeat YidD PF01809.18 KDO20735.1 - 0.055 13.4 0.2 14 5.7 0.0 2.8 2 1 1 3 3 3 0 Putative membrane protein insertion efficiency factor BacteriocIIc_cy PF12173.8 KDO20735.1 - 0.11 12.8 0.3 0.23 11.7 0.3 1.5 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like DUF5049 PF16468.5 KDO20735.1 - 0.12 12.3 0.1 21 5.1 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5049) Ank PF00023.30 KDO20735.1 - 1.5 9.4 5.4 1.3e+02 3.3 0.0 4.7 2 1 0 2 2 2 0 Ankyrin repeat SIR2 PF02146.17 KDO20736.1 - 3.6e-45 154.1 0.0 6.2e-45 153.3 0.0 1.4 1 1 0 1 1 1 1 Sir2 family vATP-synt_E PF01991.18 KDO20737.1 - 1.8e-46 158.1 7.3 2.1e-46 157.8 7.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RRM_1 PF00076.22 KDO20738.1 - 3.6e-40 135.6 1.1 1.4e-18 66.4 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KDO20738.1 - 1.1e-13 52.1 0.1 4.1e-13 50.2 0.1 2.1 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_7 PF16367.5 KDO20738.1 - 0.0017 18.5 0.1 0.69 10.1 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif RL PF17797.1 KDO20738.1 - 0.003 17.5 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 RL domain RRM_occluded PF16842.5 KDO20738.1 - 0.0036 17.1 0.3 0.36 10.7 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif HEPN_RnaseLS PF18869.1 KDO20738.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RnaseLS-like HEPN Nup35_RRM_2 PF14605.6 KDO20738.1 - 0.094 12.7 0.1 46 4.1 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KDO20738.1 - 0.12 12.5 0.0 7.5 6.7 0.0 2.9 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) FAM76 PF16046.5 KDO20738.1 - 1.7 7.9 10.7 3 7.1 10.7 1.4 1 0 0 1 1 1 0 FAM76 protein Apt1 PF10351.9 KDO20738.1 - 6.5 5.5 18.6 9.5 4.9 18.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_Rpb4 PF03874.16 KDO20739.1 - 4.6e-19 69.0 0.3 6.1e-19 68.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2757 PF10955.8 KDO20739.1 - 0.088 13.1 0.3 0.16 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) DUF5038 PF16441.5 KDO20739.1 - 0.18 11.8 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) Proteasome PF00227.26 KDO20740.1 - 6.3e-34 117.1 0.0 8.3e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TraI_2_C PF07515.11 KDO20740.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term Claudin_3 PF06653.11 KDO20742.1 - 0.02 14.9 2.2 0.02 14.9 2.2 2.3 1 1 0 2 2 2 0 Tight junction protein, Claudin-like UQ_con PF00179.26 KDO20743.1 - 2.2e-43 147.3 0.0 2.5e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KDO20743.1 - 2e-06 27.5 0.0 2.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Ank_2 PF12796.7 KDO20744.1 - 9.5e-72 237.6 23.8 4.6e-16 59.2 0.2 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20744.1 - 3.9e-45 151.7 10.0 3.1e-10 40.4 0.0 7.4 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20744.1 - 7.1e-43 139.7 12.2 0.0005 20.3 0.1 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KDO20744.1 - 2.2e-41 139.4 19.2 5.2e-07 29.8 0.0 9.7 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KDO20744.1 - 4.6e-40 134.3 36.8 1.7e-05 25.0 0.2 11.0 10 1 1 11 11 11 9 Ankyrin repeat Imm_superinfect PF14373.6 KDO20744.1 - 0.017 15.1 0.8 18 5.3 0.0 5.2 6 0 0 6 6 6 0 Superinfection immunity protein DUF3368 PF11848.8 KDO20744.1 - 0.36 10.7 3.9 32 4.4 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3368) PRA-CH PF01502.18 KDO20745.1 - 9.4e-23 79.8 0.0 1.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KDO20745.1 - 8.6e-14 51.7 0.8 2.4e-13 50.3 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KDO20745.1 - 0.023 14.8 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain UCR_UQCRX_QCR9 PF05365.12 KDO20746.1 - 2.3e-17 62.6 0.4 3.6e-17 62.0 0.4 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Thioredoxin_8 PF13905.6 KDO20747.1 - 3.1e-18 65.9 0.0 0.0013 19.0 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.21 KDO20747.1 - 6.4e-11 42.2 0.0 0.044 13.7 0.0 4.2 4 0 0 4 4 4 3 AhpC/TSA family Thioredoxin PF00085.20 KDO20747.1 - 1.7e-07 31.2 0.2 0.073 13.1 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Glutaredoxin PF00462.24 KDO20747.1 - 4e-05 23.8 0.0 0.14 12.4 0.0 4.2 5 0 0 5 5 5 1 Glutaredoxin Thioredoxin_3 PF13192.6 KDO20747.1 - 0.01 15.9 0.2 8 6.6 0.1 4.0 4 0 0 4 4 4 0 Thioredoxin domain BTB_3 PF16017.5 KDO20747.1 - 0.021 14.9 0.0 9 6.5 0.0 2.7 2 0 0 2 2 2 0 BTB/POZ domain EBP PF05241.12 KDO20748.1 - 4.5e-31 107.7 8.2 5.4e-31 107.4 8.2 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 KDO20748.1 - 0.00085 19.7 2.7 0.00085 19.7 2.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) PHB_acc PF05233.13 KDO20748.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 PHB accumulation regulatory domain Metallophos PF00149.28 KDO20750.1 - 1e-15 58.8 2.6 1.8e-15 58.0 2.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KDO20750.1 - 5e-07 30.2 0.9 1.5e-06 28.7 0.9 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KDO20750.1 - 2.4e-06 28.3 0.1 6.1e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 KDO20750.1 - 0.0011 19.2 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF1275 PF06912.11 KDO20754.1 - 0.027 14.4 1.5 0.066 13.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Ank_2 PF12796.7 KDO20756.1 - 1.7e-30 105.4 1.3 2.8e-09 37.4 0.1 5.5 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20756.1 - 1.8e-24 85.5 10.3 4.1e-09 36.5 0.1 6.0 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20756.1 - 1.5e-22 79.6 0.4 1.7e-07 31.7 0.0 6.8 3 3 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO20756.1 - 9.8e-21 73.2 7.9 4.6e-05 23.7 0.1 8.9 9 0 0 9 9 9 3 Ankyrin repeat Ank_3 PF13606.6 KDO20756.1 - 2.6e-19 67.2 4.2 0.0011 19.2 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ion_trans PF00520.31 KDO20756.1 - 2.9e-05 23.4 17.0 2.9e-05 23.4 17.0 1.8 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO20756.1 - 0.24 10.0 17.4 0.34 9.5 3.2 2.4 1 1 1 2 2 2 0 Polycystin cation channel Lar_restr_allev PF14354.6 KDO20758.1 - 0.024 15.0 1.4 0.062 13.7 1.4 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar DJ-1_PfpI PF01965.24 KDO20759.1 - 1.6e-21 76.8 0.0 2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Mito_carr PF00153.27 KDO20760.1 - 2e-50 168.7 2.2 4.7e-16 58.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4148 PF13663.6 KDO20760.1 - 0.27 11.5 3.3 0.27 11.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Sel1 PF08238.12 KDO20761.1 - 4.3e-29 100.3 6.9 1.2e-07 32.1 0.0 6.6 7 0 0 7 7 7 6 Sel1 repeat DUF440 PF04269.12 KDO20761.1 - 0.085 13.2 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF440 PX PF00787.24 KDO20762.1 - 4.6e-07 29.8 0.1 6.8e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 PX domain Myb_DNA-binding PF00249.31 KDO20763.1 - 3.8e-08 33.4 0.0 6.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MnmE_helical PF12631.7 KDO20763.1 - 0.052 13.7 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 MnmE helical domain Thioredoxin_8 PF13905.6 KDO20764.1 - 1.8e-18 66.6 0.0 4.8e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KDO20764.1 - 2e-08 34.1 0.0 3.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin PF00085.20 KDO20764.1 - 4.8e-07 29.7 0.0 1.6e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 KDO20764.1 - 1.7e-06 27.9 0.0 0.0004 20.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KDO20764.1 - 0.00058 20.3 0.0 0.0019 18.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KDO20764.1 - 0.0027 17.5 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KDO20764.1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KDO20764.1 - 0.039 14.1 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO20765.1 - 6e-19 68.2 0.4 2.2e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KDO20765.1 - 1.1e-07 31.7 0.6 2.5e-05 24.0 0.0 2.4 2 1 0 2 2 2 2 Redoxin Thioredoxin PF00085.20 KDO20765.1 - 1.4e-07 31.4 0.0 9.9e-06 25.5 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin AhpC-TSA PF00578.21 KDO20765.1 - 0.0001 22.2 0.0 0.00085 19.2 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KDO20765.1 - 0.0017 18.2 0.1 0.037 13.8 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO20765.1 - 0.004 17.6 0.1 0.023 15.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain DUF953 PF06110.11 KDO20765.1 - 0.14 11.8 0.2 1.7 8.3 0.2 2.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Myb_DNA-binding PF00249.31 KDO20766.1 - 5.7e-08 32.8 0.2 8.8e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PaREP1 PF05942.11 KDO20766.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Cation_efflux PF01545.21 KDO20767.1 - 1.3e-38 132.7 14.1 1.3e-38 132.7 14.1 1.9 2 0 0 2 2 2 1 Cation efflux family Myb_DNA-binding PF00249.31 KDO20768.1 - 5.5e-08 32.9 0.1 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4703 PF15775.5 KDO20768.1 - 0.12 12.1 0.6 0.17 11.7 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4703) FYVE PF01363.21 KDO20769.1 - 8.9e-14 51.4 28.4 3.8e-08 33.4 16.7 2.4 2 0 0 2 2 2 2 FYVE zinc finger DUF3018 PF11455.8 KDO20769.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Ank_2 PF12796.7 KDO20770.1 - 2.7e-62 207.3 6.5 3.7e-15 56.3 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO20770.1 - 2.7e-37 122.5 0.9 4e-05 23.7 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KDO20770.1 - 5e-37 124.7 7.8 7.2e-08 32.5 0.2 6.3 5 1 1 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KDO20770.1 - 8.7e-36 121.5 11.3 4.5e-08 33.2 0.0 5.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20770.1 - 5.9e-33 112.8 2.1 3.9e-08 33.7 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO20771.1 - 7.3e-43 146.7 0.0 8.4e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20771.1 - 9.4e-42 143.2 0.0 1.2e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO20771.1 - 0.00088 18.2 0.1 0.0013 17.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO20771.1 - 0.00093 19.2 0.4 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO20771.1 - 0.0019 17.2 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO20771.1 - 0.03 13.7 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO20771.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like GlcNAc PF11397.8 KDO20772.1 - 7.3e-36 124.3 0.0 4.8e-32 111.8 0.0 2.8 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 KDO20772.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 EF-hand_7 PF13499.6 KDO20773.1 - 2.8e-16 59.7 5.3 2.8e-08 34.1 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO20773.1 - 3.8e-16 57.3 7.3 0.0046 16.4 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO20773.1 - 8.9e-15 53.3 5.8 0.0028 17.4 0.0 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO20773.1 - 3.1e-11 42.2 3.5 0.011 15.2 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KDO20773.1 - 3.4e-05 23.6 2.7 0.18 11.7 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain pair WD40 PF00400.32 KDO20774.1 - 2.2e-16 59.9 17.7 0.00046 20.9 0.0 9.6 11 0 0 11 11 11 6 WD domain, G-beta repeat EF-hand_1 PF00036.32 KDO20775.1 - 1.6e-05 24.1 0.9 4.1e-05 22.8 0.9 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO20775.1 - 0.00038 20.8 0.2 0.0054 17.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO20775.1 - 0.0011 18.7 1.1 0.0034 17.2 1.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KDO20775.1 - 0.0077 15.7 1.0 0.022 14.2 1.0 1.8 2 0 0 2 2 2 1 EF hand DUF87 PF01935.17 KDO20775.1 - 0.11 12.6 2.2 0.23 11.5 0.1 2.4 2 1 1 3 3 3 0 Helicase HerA, central domain Alph_Pro_TM PF09608.10 KDO20775.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) EF-hand_8 PF13833.6 KDO20775.1 - 0.18 11.7 2.5 1.3 9.0 0.8 2.9 2 1 1 3 3 3 0 EF-hand domain pair Orexin PF02072.15 KDO20778.1 - 0.045 13.7 1.2 0.094 12.7 1.2 1.6 1 0 0 1 1 1 0 Prepro-orexin Serglycin PF04360.12 KDO20778.1 - 0.44 10.5 12.8 0.3 11.0 5.4 2.6 2 1 0 2 2 2 0 Serglycin Sensor PF13796.6 KDO20779.1 - 7e-09 35.9 25.2 2e-05 24.7 15.3 2.7 2 1 0 2 2 2 2 Putative sensor DUF1129 PF06570.11 KDO20779.1 - 2.4 7.6 4.9 7 6.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) PALP PF00291.25 KDO20780.1 - 1.4e-57 195.4 0.2 2e-57 194.9 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 KDO20780.1 - 0.0027 17.7 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WD40 PF00400.32 KDO20782.1 - 1.4e-05 25.7 3.0 6.8 7.7 0.1 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat CxC6 PF18721.1 KDO20783.1 - 2.9 8.3 28.0 19 5.6 0.1 4.2 1 1 2 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases Ricin_B_lectin PF00652.22 KDO20784.1 - 1.6e-28 99.5 12.9 4.4e-15 56.1 1.2 2.9 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO20784.1 - 1.2e-12 48.3 19.1 4.7e-05 24.0 0.1 5.2 3 2 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like DPBB_1 PF03330.18 KDO20784.1 - 0.00013 22.2 0.2 0.0004 20.6 0.2 1.9 1 0 0 1 1 1 1 Lytic transglycolase IQ PF00612.27 KDO20785.1 - 0.011 15.5 0.8 0.011 15.5 0.8 4.3 5 0 0 5 5 5 0 IQ calmodulin-binding motif ArnB_C PF18677.1 KDO20785.1 - 0.042 14.0 2.1 0.76 9.9 0.1 3.3 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain GvpK PF05121.12 KDO20786.1 - 0.19 11.8 6.8 1.2 9.2 1.7 2.6 1 1 0 2 2 2 0 Gas vesicle protein K V_ATPase_I PF01496.19 KDO20786.1 - 0.76 7.6 8.4 1 7.2 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YjbH PF06082.11 KDO20786.1 - 1 8.1 5.8 1.4 7.7 5.8 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH HR1 PF02185.16 KDO20786.1 - 2.5 8.3 10.0 0.27 11.4 1.8 3.2 3 1 1 4 4 4 0 Hr1 repeat THOC7 PF05615.13 KDO20786.1 - 3.3 8.0 15.1 0.39 11.0 4.8 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 Spc24 PF08286.11 KDO20786.1 - 4.7 7.5 6.4 1 9.6 1.4 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 KDO20786.1 - 6.1 6.6 13.7 4.2 7.1 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KDO20786.1 - 9.8 5.4 14.6 16 4.8 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CN_hydrolase PF00795.22 KDO20787.1 - 5e-21 75.2 0.0 4.8e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4386 PF14329.6 KDO20788.1 - 0.15 11.9 0.2 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) EMP24_GP25L PF01105.24 KDO20789.1 - 2.1e-09 37.6 0.3 8.7e-06 25.8 0.0 2.5 3 0 0 3 3 3 2 emp24/gp25L/p24 family/GOLD DUF3792 PF12670.7 KDO20790.1 - 0.38 10.9 9.1 0.1 12.8 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) PEPCK_ATP PF01293.20 KDO20791.1 - 0.0016 17.2 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase ADP_ribosyl_GH PF03747.14 KDO20792.1 - 8.7e-27 94.6 0.8 1.1e-26 94.3 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TPR_12 PF13424.6 KDO20793.1 - 1.9e-09 37.7 7.0 0.0069 16.7 1.9 3.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20793.1 - 7.6e-05 22.5 1.5 1.1 9.6 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20793.1 - 0.00014 21.5 0.1 0.013 15.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20793.1 - 0.00033 21.2 3.1 0.2 12.4 0.8 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20793.1 - 0.00034 20.4 3.4 0.54 10.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20793.1 - 0.019 15.0 1.7 0.49 10.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20793.1 - 0.091 13.0 0.0 2 8.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NADH-PPase PF09297.11 KDO20793.1 - 0.12 12.0 0.9 8.9 6.1 0.3 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain TPR_14 PF13428.6 KDO20793.1 - 5.4 8.1 8.0 34 5.6 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20794.1 - 3e-10 40.2 2.0 8e-06 26.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20794.1 - 8.9e-06 25.4 0.1 0.12 12.2 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO20794.1 - 0.0013 18.9 0.6 0.25 11.6 0.5 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ATP13 PF12921.7 KDO20794.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase expression FUR PF01475.19 KDO20794.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family TPR_14 PF13428.6 KDO20794.1 - 0.29 12.1 4.7 37 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20794.1 - 0.51 10.9 6.1 1.8 9.1 1.9 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20795.1 - 8.1e-10 38.9 4.2 1.3e-05 25.4 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20795.1 - 2.6e-05 23.9 0.4 0.14 12.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ATP13 PF12921.7 KDO20795.1 - 0.055 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ATPase expression DUF5614 PF18474.1 KDO20795.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5614) TPR_1 PF00515.28 KDO20795.1 - 0.28 11.1 1.4 22 5.1 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20795.1 - 0.78 10.3 4.8 2.2 8.9 1.4 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_M13_N PF05649.13 KDO20797.1 - 1.3e-64 219.3 0.0 1.7e-64 218.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO20797.1 - 2.4e-60 203.6 0.0 6.7e-60 202.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M13 Methyltransf_16 PF10294.9 KDO20798.1 - 6.2e-20 71.6 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KDO20798.1 - 1.8e-09 37.5 0.0 3.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO20798.1 - 5.9e-09 36.5 0.0 1.6e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO20798.1 - 2.3e-08 33.8 0.1 4.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO20798.1 - 9.3e-07 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KDO20798.1 - 4e-05 23.5 0.0 6.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO20798.1 - 4.5e-05 24.1 0.0 0.00013 22.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO20798.1 - 0.00025 21.6 0.0 0.00059 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO20798.1 - 0.00043 20.0 0.0 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 KDO20798.1 - 0.00088 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NNMT_PNMT_TEMT PF01234.17 KDO20798.1 - 0.031 13.5 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_18 PF12847.7 KDO20798.1 - 0.032 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KDO20798.1 - 0.054 12.8 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KDO20798.1 - 0.09 12.1 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TruB_C_2 PF16198.5 KDO20799.1 - 0.086 13.0 0.8 0.78 9.9 0.1 2.6 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Fib_alpha PF08702.10 KDO20799.1 - 7.1 6.8 10.9 11 6.2 1.8 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ChapFlgA_N PF17656.1 KDO20803.1 - 0.012 15.8 0.2 0.056 13.6 0.0 2.1 2 1 1 3 3 3 0 FlgA N-terminal domain DUF4209 PF13910.6 KDO20804.1 - 9.4e-19 67.4 0.0 2e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) EB1 PF03271.17 KDO20805.1 - 0.086 13.1 0.1 0.11 12.8 0.1 1.3 1 1 0 1 1 1 0 EB1-like C-terminal motif LRR_6 PF13516.6 KDO20806.1 - 2.6e-13 48.9 18.2 0.00012 21.9 0.1 7.6 9 0 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.6 KDO20806.1 - 0.00028 20.6 6.6 0.53 10.1 0.1 4.8 4 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KDO20806.1 - 0.039 14.4 5.3 0.57 10.7 0.4 4.0 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO20807.1 - 2.3e-17 61.5 3.3 0.00084 19.2 0.1 7.5 6 0 0 6 6 6 5 Leucine Rich repeat WSD PF15613.6 KDO20807.1 - 0.032 14.7 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif LRR_1 PF00560.33 KDO20807.1 - 0.055 14.0 0.3 15 6.6 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO20808.1 - 2.9e-10 39.4 17.3 0.23 11.6 0.0 8.4 9 0 0 9 9 9 4 Leucine Rich repeat LRR_9 PF14580.6 KDO20808.1 - 0.00028 20.4 2.7 0.24 10.9 0.1 3.0 3 1 0 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KDO20808.1 - 0.00061 19.5 10.5 0.82 9.5 0.0 5.9 5 1 1 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 KDO20808.1 - 0.046 14.2 13.4 3.2 8.3 0.2 6.1 2 2 6 8 8 8 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO20810.1 - 8.4e-09 34.8 16.3 0.31 11.2 0.1 7.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 KDO20810.1 - 0.00073 19.9 7.4 8.5 7.0 0.0 6.3 4 3 4 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO20810.1 - 0.054 13.3 13.9 1.8 8.4 0.1 6.3 5 3 1 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 KDO20811.1 - 8e-06 25.5 22.2 0.00013 21.7 0.0 7.4 8 1 1 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 KDO20811.1 - 0.0021 18.4 5.1 4.3 7.9 0.0 5.3 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) DUF604 PF04646.12 KDO20811.1 - 0.084 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 LRR_8 PF13855.6 KDO20811.1 - 0.18 11.6 6.9 0.19 11.5 0.4 4.1 4 1 2 6 6 6 0 Leucine rich repeat MFS_1 PF07690.16 KDO20812.1 - 1.9e-31 109.3 43.9 1.9e-31 109.3 43.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KDO20813.1 - 9.7e-06 24.7 32.7 0.00027 20.0 11.6 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Mersacidin PF16934.5 KDO20813.1 - 0.025 14.3 1.1 0.025 14.3 1.1 2.8 3 1 1 4 4 4 0 Two-component Enterococcus faecalis cytolysin (EFC) HSF_DNA-bind PF00447.17 KDO20814.1 - 2.5e-20 72.9 0.2 3.4e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding MFS_1 PF07690.16 KDO20815.1 - 3.1e-33 115.2 40.0 3.1e-33 115.2 40.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily zf-RING_2 PF13639.6 KDO20816.1 - 2e-08 34.4 19.2 2e-08 34.4 19.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KDO20816.1 - 5.2e-07 29.3 11.8 5.2e-07 29.3 11.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger PX PF00787.24 KDO20816.1 - 1.1e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 KDO20816.1 - 1.2e-05 25.5 16.5 5.4e-05 23.4 16.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO20816.1 - 0.0016 18.2 18.2 0.0016 18.2 18.2 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO20816.1 - 0.0017 18.4 12.8 0.0049 16.9 11.7 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO20816.1 - 0.0022 18.0 16.8 0.0036 17.3 15.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO20816.1 - 0.036 13.9 19.1 0.067 13.1 18.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO20816.1 - 0.067 13.2 15.6 0.19 11.7 15.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 KDO20816.1 - 0.2 11.9 10.5 0.65 10.2 10.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TSNAXIP1_N PF15739.5 KDO20819.1 - 4.4e-12 46.3 3.3 4.4e-12 46.3 3.3 3.0 1 1 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Sec20 PF03908.13 KDO20819.1 - 0.0079 16.1 3.9 0.016 15.1 2.0 2.5 1 1 1 2 2 2 1 Sec20 KASH_CCD PF14662.6 KDO20819.1 - 0.017 15.0 15.4 0.19 11.5 3.1 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH SesA PF17107.5 KDO20819.1 - 0.036 14.3 0.7 0.036 14.3 0.7 2.7 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FUSC PF04632.12 KDO20819.1 - 0.99 7.9 6.7 1.7 7.0 6.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIN_8 PF18476.1 KDO20819.1 - 1 9.1 4.9 1.9 8.3 4.9 1.5 1 0 0 1 1 1 0 PIN like domain NPV_P10 PF05531.12 KDO20819.1 - 1 9.8 2.8 6.4 7.3 0.6 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KDO20819.1 - 2.5 7.4 18.2 1.5 8.2 4.3 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 KDO20819.1 - 3.9 7.0 11.2 8.4 5.9 11.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit THOC7 PF05615.13 KDO20819.1 - 4.6 7.5 10.6 12 6.2 10.6 1.8 1 0 0 1 1 1 0 Tho complex subunit 7 Phage_Mu_Gam PF07352.12 KDO20819.1 - 4.7 7.1 8.0 1.6 8.6 4.4 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Seryl_tRNA_N PF02403.22 KDO20819.1 - 9.9 6.4 13.6 5.9 7.2 3.6 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Longin PF13774.6 KDO20820.1 - 0.0016 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1507 PF07408.11 KDO20820.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) zf-RING_2 PF13639.6 KDO20821.1 - 2e-13 50.4 5.8 5.2e-13 49.1 5.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO20821.1 - 1.7e-09 37.8 7.4 5.6e-09 36.1 7.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO20821.1 - 1.7e-08 34.2 6.8 5.6e-08 32.5 6.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO20821.1 - 2.9e-07 30.3 3.7 5.4e-07 29.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO20821.1 - 4e-07 29.9 2.4 9.2e-07 28.8 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO20821.1 - 6.9e-07 29.0 5.4 2e-06 27.6 5.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO20821.1 - 7e-07 28.9 2.8 2e-06 27.4 2.8 1.8 1 1 0 1 1 1 1 RING-like zinc finger PX PF00787.24 KDO20821.1 - 2.4e-06 27.5 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 KDO20821.1 - 2.2e-05 24.3 3.5 2.2e-05 24.3 3.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO20821.1 - 0.00014 21.8 3.2 0.00038 20.5 3.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO20821.1 - 0.002 18.0 5.3 0.0038 17.0 2.9 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO20821.1 - 0.0047 16.5 6.1 0.012 15.2 6.1 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KDO20821.1 - 0.011 15.7 2.5 0.011 15.7 2.5 2.0 2 0 0 2 2 1 0 Zinc-finger RINGv PF12906.7 KDO20821.1 - 0.054 13.6 3.7 0.15 12.2 3.7 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO20821.1 - 0.18 12.0 7.9 0.099 12.8 4.3 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.8 KDO20821.1 - 0.18 11.6 1.8 0.46 10.3 1.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.15 KDO20821.1 - 0.87 9.2 3.6 13 5.4 0.2 2.4 2 0 0 2 2 2 0 RecR protein Zf_RING PF16744.5 KDO20821.1 - 2.2 8.5 5.3 2 8.6 2.6 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING-like PF08746.11 KDO20821.1 - 5.1 7.5 7.0 0.65 10.3 2.6 1.8 2 0 0 2 2 2 0 RING-like domain AMP-binding PF00501.28 KDO20822.1 - 1.5e-20 73.2 0.7 2e-20 72.8 0.7 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PBECR3 PF18812.1 KDO20822.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 zf-RING_2 PF13639.6 KDO20823.1 - 5.7e-12 45.8 11.5 1.1e-11 44.9 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO20823.1 - 3e-09 36.8 2.4 3e-09 36.8 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO20823.1 - 2.1e-08 33.8 8.2 3.7e-08 33.0 5.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO20823.1 - 1e-05 25.7 13.9 3.4e-05 24.0 13.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain PX PF00787.24 KDO20823.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-C3HC4_3 PF13920.6 KDO20823.1 - 1.6e-05 24.6 9.0 3.6e-05 23.5 9.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO20823.1 - 2.8e-05 23.9 12.7 8.8e-05 22.3 12.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO20823.1 - 2.8e-05 23.9 10.9 5.3e-05 23.0 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO20823.1 - 0.004 17.0 10.8 0.03 14.2 10.9 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO20823.1 - 0.006 16.5 8.9 0.011 15.6 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 KDO20823.1 - 0.22 11.7 10.0 2 8.6 10.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KDO20823.1 - 0.4 10.9 8.1 0.86 9.8 8.1 1.6 1 1 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 KDO20823.1 - 1.3 9.1 12.2 2 8.5 10.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KDO20823.1 - 2.7 8.2 11.1 2.1 8.6 6.1 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KDO20824.1 - 4.1e-13 49.4 4.6 8.4e-13 48.4 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO20824.1 - 4.6e-10 39.6 5.5 1.3e-09 38.2 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO20824.1 - 1.9e-08 34.2 1.4 3.7e-08 33.3 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KDO20824.1 - 3.4e-07 30.0 3.2 6e-07 29.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO20824.1 - 3.8e-07 29.8 6.0 1.2e-06 28.2 6.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO20824.1 - 5.3e-07 29.5 3.5 5.3e-07 29.5 3.5 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO20824.1 - 5.7e-07 29.4 0.5 5.7e-07 29.4 0.5 2.3 2 1 1 3 3 3 1 RING-type zinc-finger FANCL_C PF11793.8 KDO20824.1 - 2.4e-06 27.6 3.2 2.2e-05 24.5 3.2 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 KDO20824.1 - 2.4e-06 27.2 2.7 2.4e-06 27.2 2.7 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KDO20824.1 - 3.8e-05 23.5 4.6 8.2e-05 22.4 4.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO20824.1 - 0.0004 19.9 6.1 0.001 18.6 6.1 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO20824.1 - 0.00062 19.5 3.1 0.0011 18.7 3.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KDO20824.1 - 0.0064 16.3 6.1 0.019 14.8 6.2 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KDO20824.1 - 0.051 13.7 5.9 0.15 12.2 5.8 1.8 1 1 1 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.6 KDO20824.1 - 0.1 12.6 5.6 0.29 11.1 1.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RVT PF13966.6 KDO20824.1 - 0.11 13.2 2.2 7.8 7.3 0.6 3.0 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase zf-RING-like PF08746.11 KDO20824.1 - 0.12 12.7 1.2 0.12 12.7 1.2 1.7 2 0 0 2 2 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KDO20824.1 - 0.92 9.7 6.4 10 6.4 7.1 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KDO20824.1 - 0.93 9.6 5.8 0.14 12.2 1.7 1.9 2 0 0 2 2 1 0 Zinc-finger zf-RING_2 PF13639.6 KDO20825.1 - 1.9e-10 40.9 5.3 3.5e-10 40.0 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO20825.1 - 1.6e-07 31.5 6.6 4.4e-07 30.1 6.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO20825.1 - 8e-06 25.6 4.9 1.5e-05 24.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO20825.1 - 1.9e-05 24.4 6.4 5.2e-05 23.0 6.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO20825.1 - 2.2e-05 24.4 3.3 6.2e-05 23.0 3.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KDO20825.1 - 4e-05 23.3 7.1 0.00013 21.6 7.1 1.9 1 1 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KDO20825.1 - 6.1e-05 22.8 3.3 0.00016 21.4 3.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KDO20825.1 - 0.00013 21.9 1.8 0.00071 19.5 2.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO20825.1 - 0.00022 21.1 3.9 0.00045 20.1 3.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KDO20825.1 - 0.0021 17.6 5.4 0.0057 16.3 5.4 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KDO20825.1 - 0.0044 16.8 3.2 0.011 15.6 3.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KDO20825.1 - 0.0078 16.4 5.1 0.066 13.4 5.1 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KDO20825.1 - 0.012 15.6 3.2 0.042 13.9 3.2 1.9 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KDO20825.1 - 0.028 14.5 4.1 0.068 13.3 4.1 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 KDO20825.1 - 0.073 12.9 2.4 0.15 11.9 1.1 2.3 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit OTT_1508_deam PF14441.6 KDO20825.1 - 0.23 11.5 1.9 0.55 10.3 1.9 1.7 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-C3HC4_4 PF15227.6 KDO20825.1 - 0.56 10.4 4.3 0.24 11.6 1.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KDO20826.1 - 4.1e-10 39.8 6.1 9.1e-10 38.7 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO20826.1 - 5.1e-08 33.1 8.8 2e-07 31.2 8.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO20826.1 - 1.3e-06 28.4 3.6 2.3e-06 27.6 3.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO20826.1 - 9.7e-06 25.5 4.5 1.9e-05 24.6 4.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO20826.1 - 2.9e-05 23.8 5.8 6e-05 22.8 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO20826.1 - 5.9e-05 22.7 4.8 0.00014 21.5 4.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KDO20826.1 - 0.00011 22.0 3.2 0.00011 22.0 3.2 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KDO20826.1 - 0.00015 21.5 11.0 0.0011 18.7 11.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO20826.1 - 0.0002 21.1 6.4 0.00087 19.1 6.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO20826.1 - 0.00085 19.3 5.1 0.0018 18.2 5.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3H2C3 PF17122.5 KDO20826.1 - 0.0044 17.0 2.4 0.0044 17.0 2.4 2.7 4 0 0 4 4 4 1 Zinc-finger zf-Nse PF11789.8 KDO20826.1 - 0.033 14.0 1.2 0.14 12.0 1.2 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.6 KDO20826.1 - 0.035 14.3 1.0 0.12 12.5 0.9 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 KDO20826.1 - 0.19 11.9 3.5 0.83 9.9 3.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KDO20826.1 - 1 9.5 6.1 3.2 8.0 6.2 1.8 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KDO20826.1 - 1.4 8.6 11.7 0.26 11.0 7.5 2.1 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 KDO20827.1 - 3.9e-16 59.0 43.0 1.1e-09 38.4 4.6 3.6 2 2 1 3 3 3 2 IBR domain, a half RING-finger domain Auto_anti-p27 PF06677.12 KDO20827.1 - 0.029 14.5 1.7 0.029 14.5 1.7 4.5 5 2 1 6 6 6 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.21 KDO20829.1 - 6.2e-24 84.0 92.5 4.6e-08 33.2 7.6 6.5 6 0 0 6 6 6 5 IBR domain, a half RING-finger domain C1_4 PF07975.12 KDO20829.1 - 0.036 14.3 3.4 0.036 14.3 3.4 7.2 4 2 0 6 6 6 0 TFIIH C1-like domain IBR PF01485.21 KDO20830.1 - 8.2e-17 61.2 41.8 4.4e-08 33.2 6.4 3.7 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain IBR PF01485.21 KDO20831.1 - 5.9e-15 55.2 42.1 4.9e-07 29.9 7.3 3.5 2 1 1 3 3 3 3 IBR domain, a half RING-finger domain RsbRD_N PF14361.6 KDO20832.1 - 0.15 12.8 2.4 0.2 12.4 2.4 1.1 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF755 PF05501.11 KDO20832.1 - 4.6 7.5 11.7 11 6.4 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IBR PF01485.21 KDO20833.1 - 3.3e-16 59.2 32.2 9e-07 29.0 3.8 3.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KDO20833.1 - 0.014 15.7 3.9 0.014 15.7 3.9 4.1 3 1 0 3 3 3 0 Ring finger domain DUF1206 PF06724.11 KDO20833.1 - 0.071 13.2 1.0 0.071 13.2 1.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) zf-UDP PF14569.6 KDO20833.1 - 5.5 7.2 21.7 0.13 12.4 2.9 3.0 2 1 0 2 2 2 0 Zinc-binding RING-finger Zip PF02535.22 KDO20834.1 - 2.5e-29 102.5 12.4 1.2e-25 90.5 12.4 3.0 1 1 0 1 1 1 1 ZIP Zinc transporter His_Phos_2 PF00328.22 KDO20835.1 - 1.5e-15 57.4 0.0 1.5e-14 54.2 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-RING_2 PF13639.6 KDO20836.1 - 2.3e-13 50.2 7.9 2.3e-13 50.2 7.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KDO20836.1 - 1.8e-08 34.6 10.2 1.8e-08 34.6 10.2 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO20836.1 - 3.4e-06 27.0 4.8 3.4e-06 27.0 4.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO20836.1 - 3.9e-06 26.6 10.9 2.5e-05 24.0 10.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO20836.1 - 7.3e-06 25.7 7.5 0.00015 21.6 7.1 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KDO20836.1 - 7.9e-06 25.5 3.1 7.9e-06 25.5 3.1 2.3 2 1 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO20836.1 - 1.4e-05 24.9 8.1 3.4e-05 23.6 7.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO20836.1 - 0.00021 21.1 9.1 0.0011 18.7 9.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO20836.1 - 0.00052 19.9 8.0 0.00052 19.9 8.0 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO20836.1 - 0.0011 19.0 9.2 0.0018 18.3 7.4 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KDO20836.1 - 0.0043 16.9 3.4 1.4 8.8 2.0 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_16 PF17034.5 KDO20836.1 - 0.026 14.7 5.8 0.16 12.2 5.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon like family FANCL_C PF11793.8 KDO20836.1 - 0.035 14.3 7.3 0.18 12.0 7.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain U-box PF04564.15 KDO20836.1 - 0.051 13.7 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 U-box domain Zn_ribbon_17 PF17120.5 KDO20836.1 - 0.18 11.4 11.0 0.87 9.3 11.0 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KDO20836.1 - 0.75 9.6 8.3 2.5 8.0 8.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KDO20836.1 - 0.99 9.5 9.4 0.67 10.0 6.1 2.5 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 KDO20836.1 - 1 9.6 8.9 3.7 7.8 7.9 2.6 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING SDF PF00375.18 KDO20837.1 - 5e-68 229.9 24.8 6.2e-68 229.6 24.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Cytochrom_B_C PF00032.17 KDO20838.1 - 8.7 6.7 11.3 0.22 11.9 0.7 2.9 2 1 2 4 4 4 0 Cytochrome b(C-terminal)/b6/petD DUF4464 PF14713.6 KDO20839.1 - 3.2e-86 288.5 1.2 9.3e-85 283.7 1.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4464) ATG16 PF08614.11 KDO20840.1 - 0.00064 20.0 11.1 0.0014 18.9 10.9 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Cast PF10174.9 KDO20840.1 - 0.0079 14.5 6.8 0.01 14.1 6.8 1.3 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GP24_25 PF17388.2 KDO20840.1 - 0.029 14.4 0.4 0.068 13.2 0.2 1.8 1 1 0 1 1 1 0 Tail assembly gene products 24 & 25 BLOC1_2 PF10046.9 KDO20840.1 - 0.031 14.6 2.0 0.17 12.2 1.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LKAAEAR PF15478.6 KDO20840.1 - 0.046 14.0 5.3 0.047 14.0 0.3 2.5 2 1 0 2 2 2 0 Family of unknown function with LKAAEAR motif CENP-F_leu_zip PF10473.9 KDO20840.1 - 0.059 13.4 13.1 0.31 11.0 2.0 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 KDO20840.1 - 0.061 13.6 3.6 0.91 9.9 0.1 3.1 3 1 0 3 3 3 0 TSC-22/dip/bun family FlxA PF14282.6 KDO20840.1 - 0.07 13.1 0.1 0.07 13.1 0.1 2.8 2 1 1 3 3 3 0 FlxA-like protein ABC_tran_CTD PF16326.5 KDO20840.1 - 0.079 13.2 0.1 0.079 13.2 0.1 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain Laminin_II PF06009.12 KDO20840.1 - 0.16 12.0 6.7 1.7 8.7 5.2 2.1 1 1 0 2 2 2 0 Laminin Domain II SKA2 PF16740.5 KDO20840.1 - 0.17 11.6 6.5 0.85 9.4 0.5 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 BRE1 PF08647.11 KDO20840.1 - 0.18 11.9 6.3 0.34 11.0 2.2 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CdvA PF18822.1 KDO20840.1 - 0.43 10.4 5.1 0.2 11.5 1.0 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF4200 PF13863.6 KDO20840.1 - 0.64 10.4 7.6 0.13 12.7 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 KDO20840.1 - 0.68 10.2 8.5 0.14 12.4 3.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABATE PF07336.11 KDO20840.1 - 1.1 10.0 5.5 9.3 6.9 3.7 2.3 2 1 0 2 2 2 0 Putative stress-induced transcription regulator Spc7 PF08317.11 KDO20840.1 - 2.3 7.0 11.9 1.4 7.7 9.2 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Peptidase_C1 PF00112.23 KDO20842.1 - 2.6e-58 197.7 13.0 4.5e-58 196.9 13.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20842.1 - 0.0022 16.8 1.5 0.3 9.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Fer4_6 PF12837.7 KDO20842.1 - 6.1 7.1 6.2 6.8 6.9 0.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain SPRY PF00622.28 KDO20843.1 - 4.7e-13 49.3 0.0 7.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Ribonuc_P_40 PF08584.11 KDO20844.1 - 1.7e-41 142.4 0.0 2.1e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RRM_1 PF00076.22 KDO20845.1 - 3.8e-17 61.9 0.0 1.7e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO20845.1 - 0.00014 21.6 0.0 0.51 10.2 0.0 2.3 2 1 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KDO20845.1 - 0.0035 17.4 0.1 0.72 10.0 0.1 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 KDO20845.1 - 0.0053 16.8 0.0 0.016 15.3 0.0 1.8 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO20845.1 - 0.034 14.1 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TPR_17 PF13431.6 KDO20846.1 - 1.6e-09 37.5 13.8 0.73 10.4 0.1 10.3 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20846.1 - 5.7e-07 29.1 33.1 0.098 12.5 0.0 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20846.1 - 7.9e-06 25.6 48.6 0.11 12.6 0.1 13.1 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20846.1 - 0.0041 16.8 27.4 2.9 7.7 0.0 9.8 11 0 0 11 11 11 3 TPR repeat TPR_16 PF13432.6 KDO20846.1 - 0.0057 17.3 81.5 0.01 16.4 1.9 12.7 12 3 4 16 16 16 6 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20846.1 - 0.028 14.6 22.0 0.38 11.1 0.2 9.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20846.1 - 0.029 15.2 0.0 0.029 15.2 0.0 17.7 16 6 7 23 23 23 0 Tetratricopeptide repeat AAA_13 PF13166.6 KDO20847.1 - 5.3e-06 25.4 8.6 7.5e-06 24.9 8.6 1.1 1 0 0 1 1 1 1 AAA domain TMF_DNA_bd PF12329.8 KDO20847.1 - 0.00019 21.4 19.7 0.099 12.7 1.2 3.5 2 2 1 3 3 3 3 TATA element modulatory factor 1 DNA binding FmiP_Thoc5 PF09766.9 KDO20847.1 - 0.00032 20.1 8.2 0.00049 19.5 8.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 CENP-F_leu_zip PF10473.9 KDO20847.1 - 0.0008 19.4 17.2 0.12 12.4 3.8 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 KDO20847.1 - 0.0016 16.9 9.6 0.0025 16.3 9.6 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Shisa PF13908.6 KDO20847.1 - 0.0061 16.8 0.9 0.0061 16.8 0.9 2.1 3 0 0 3 3 1 1 Wnt and FGF inhibitory regulator ZapB PF06005.12 KDO20847.1 - 0.017 15.6 4.9 0.017 15.6 4.9 3.8 3 1 1 4 4 3 0 Cell division protein ZapB Spc7 PF08317.11 KDO20847.1 - 0.019 13.9 19.4 0.58 9.0 3.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KDO20847.1 - 0.019 15.1 20.7 0.024 14.7 8.5 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KDO20847.1 - 0.045 14.3 22.8 0.21 12.1 15.5 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2001 PF09393.10 KDO20847.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube protein MPS2 PF17060.5 KDO20847.1 - 0.081 12.2 4.2 0.1 11.8 3.3 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 TMF_TATA_bd PF12325.8 KDO20847.1 - 0.097 12.9 16.1 1.2 9.4 6.0 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Acetyltransf_4 PF13420.7 KDO20847.1 - 0.11 12.6 0.6 0.19 11.8 0.6 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PI3K_P85_iSH2 PF16454.5 KDO20847.1 - 0.14 11.7 8.8 0.63 9.6 1.6 2.9 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FapA PF03961.13 KDO20847.1 - 0.15 10.6 7.9 0.32 9.6 7.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A CENP-K PF11802.8 KDO20847.1 - 0.17 11.4 6.3 0.27 10.8 6.3 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF1664 PF07889.12 KDO20847.1 - 0.21 11.6 13.7 1.4 9.0 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 KDO20847.1 - 0.33 10.7 16.3 1.8 8.3 6.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 KDO20847.1 - 0.38 10.3 22.9 1.5 8.3 5.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4763 PF15960.5 KDO20847.1 - 0.39 10.0 10.9 0.45 9.8 8.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Cep57_CLD_2 PF14197.6 KDO20847.1 - 0.42 10.7 16.0 3.8 7.7 0.5 4.2 3 1 1 4 4 3 0 Centrosome localisation domain of PPC89 DUF4201 PF13870.6 KDO20847.1 - 0.42 10.3 11.5 0.4 10.4 5.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HMMR_N PF15905.5 KDO20847.1 - 0.57 9.6 18.0 2.1 7.7 17.9 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cortex-I_coil PF09304.10 KDO20847.1 - 0.7 10.1 12.4 1.2 9.4 8.0 2.8 1 1 0 2 2 2 0 Cortexillin I, coiled coil FlaC_arch PF05377.11 KDO20847.1 - 0.73 10.3 7.0 2.2 8.7 0.2 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 KDO20847.1 - 0.85 9.9 16.2 0.9 9.9 1.1 3.1 2 1 2 4 4 3 0 Uncharacterized conserved protein Occludin_ELL PF07303.13 KDO20847.1 - 1.1 10.1 4.8 35 5.2 0.3 3.2 1 1 1 2 2 2 0 Occludin homology domain Atg14 PF10186.9 KDO20847.1 - 1.2 8.2 13.7 2.9 6.9 13.7 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 KDO20847.1 - 1.2 9.5 15.5 10 6.6 0.9 4.5 1 1 2 4 4 4 0 Csm1 N-terminal domain GAS PF13851.6 KDO20847.1 - 1.6 8.0 17.7 1.3 8.4 8.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 KDO20847.1 - 1.7 8.9 12.0 3.6 7.8 2.8 2.9 1 1 1 3 3 3 0 JNK-interacting protein leucine zipper II BLOC1_2 PF10046.9 KDO20847.1 - 1.7 9.0 13.5 2.8 8.3 3.8 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 KDO20847.1 - 1.9 8.7 18.3 1.2 9.4 6.4 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 KDO20847.1 - 2.2 9.0 8.7 7.6e+02 0.8 8.3 3.3 1 1 0 1 1 1 0 Initiation control protein YabA Fib_alpha PF08702.10 KDO20847.1 - 2.3 8.4 10.7 1.4 9.1 3.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KDO20847.1 - 2.4 8.2 11.1 13 5.9 4.4 3.0 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BRE1 PF08647.11 KDO20847.1 - 3 8.0 20.2 2.7 8.1 9.9 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Snapin_Pallidin PF14712.6 KDO20847.1 - 3.3 8.2 15.5 2.1 8.8 5.3 3.9 3 1 1 4 4 3 0 Snapin/Pallidin USP8_interact PF08941.10 KDO20847.1 - 3.5 7.4 8.4 12 5.7 1.2 2.2 1 1 1 2 2 2 0 USP8 interacting FAP206 PF12018.8 KDO20847.1 - 3.8 6.9 9.7 3.6 7.0 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function Fez1 PF06818.15 KDO20847.1 - 3.9 7.9 15.7 9.4 6.6 15.7 1.8 1 1 0 1 1 1 0 Fez1 DUF3450 PF11932.8 KDO20847.1 - 4.1 6.6 24.1 0.069 12.4 8.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Spectrin PF00435.21 KDO20847.1 - 4.3 7.9 16.9 22 5.6 10.7 3.2 1 1 1 2 2 1 0 Spectrin repeat 5_nucleotid PF05761.14 KDO20847.1 - 4.8 6.0 7.8 0.71 8.7 3.3 1.8 1 1 1 2 2 2 0 5' nucleotidase family Tropomyosin_1 PF12718.7 KDO20847.1 - 5.2 7.2 20.1 1.4 9.1 9.4 2.7 1 1 1 2 2 2 0 Tropomyosin like TPR_MLP1_2 PF07926.12 KDO20847.1 - 6.7 6.8 28.6 2.6 8.1 12.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 KDO20847.1 - 6.8 6.5 23.8 13 5.6 2.7 4.6 1 1 4 5 5 5 0 Septum formation initiator TBCA PF02970.16 KDO20847.1 - 7.4 7.0 13.7 1.2 9.5 1.7 2.6 1 1 1 2 2 2 0 Tubulin binding cofactor A JAKMIP_CC3 PF16034.5 KDO20847.1 - 7.7 6.4 15.7 0.3 11.0 6.0 2.5 1 1 1 2 2 2 0 JAKMIP CC3 domain Swi5 PF07061.11 KDO20847.1 - 8.1 6.6 14.3 22 5.2 0.1 4.1 2 1 0 2 2 1 0 Swi5 FH2 PF02181.23 KDO20847.1 - 9.6 5.2 12.4 9.9 5.2 3.7 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain DNA_primase_lrg PF04104.14 KDO20848.1 - 1.2e-74 251.1 0.0 2.1e-74 250.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit LamB_YcsF PF03746.16 KDO20848.1 - 0.044 13.5 0.4 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 LamB/YcsF family Proteasome PF00227.26 KDO20850.1 - 5.3e-46 156.5 0.0 6.9e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO20850.1 - 4.2e-13 48.7 0.0 7.1e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1295 PF06966.12 KDO20851.1 - 6.6e-48 163.3 8.0 7.8e-48 163.0 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KDO20851.1 - 3.8e-11 43.2 1.6 7.7e-11 42.2 1.6 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KDO20851.1 - 4.5e-05 23.8 0.2 0.00013 22.3 0.2 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KDO20851.1 - 0.0001 21.2 1.5 0.0001 21.2 1.5 1.7 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KDO20851.1 - 0.00011 22.5 0.5 0.00031 21.1 0.5 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase fn3 PF00041.21 KDO20852.1 - 9.6e-35 118.8 0.2 1e-08 35.4 0.0 7.6 8 0 0 8 8 8 5 Fibronectin type III domain Beta_helix PF13229.6 KDO20852.1 - 1.5e-19 70.4 52.0 5.1e-05 23.2 4.2 6.8 2 2 4 6 6 6 6 Right handed beta helix region TRP PF06011.12 KDO20852.1 - 1.2e-07 30.9 2.0 1.2e-07 30.9 2.0 2.7 4 0 0 4 4 4 1 Transient receptor potential (TRP) ion channel Pur_ac_phosph_N PF16656.5 KDO20852.1 - 3e-07 30.9 0.8 1.1 9.9 0.0 6.4 6 0 0 6 6 6 1 Purple acid Phosphatase, N-terminal domain NosD PF05048.13 KDO20852.1 - 6.1e-05 22.4 30.4 0.0075 15.6 1.1 6.1 2 2 4 6 6 6 4 Periplasmic copper-binding protein (NosD) NCD3G PF07562.14 KDO20852.1 - 0.48 10.4 8.7 0.036 14.0 1.0 2.8 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUSP PF06337.12 KDO20853.1 - 0.00046 20.8 0.0 0.0011 19.6 0.0 1.7 1 1 0 1 1 1 1 DUSP domain Pkinase PF00069.25 KDO20854.1 - 7.3e-51 173.0 0.0 1e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20854.1 - 5.8e-49 166.7 0.0 7.7e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO20854.1 - 1.6e-05 23.9 0.1 5.1e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO20854.1 - 0.00037 19.9 0.1 0.00067 19.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO20854.1 - 0.0005 20.1 0.0 0.0032 17.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO20854.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Asp_Arg_Hydrox PF05118.15 KDO20855.1 - 3.4e-43 147.2 0.0 5e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 KDO20855.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ribosomal_L7Ae PF01248.26 KDO20856.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PEP-utilizers PF00391.23 KDO20856.1 - 0.018 14.7 0.7 0.056 13.2 0.7 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, mobile domain TPP_enzyme_C PF02775.21 KDO20856.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF778 PF05608.12 KDO20858.1 - 1.6e-32 113.4 2.7 2.1e-19 70.6 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) ANAPC4_WD40 PF12894.7 KDO20860.1 - 1.5e-12 47.6 0.3 1.2e-05 25.5 0.1 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO20860.1 - 5.4e-06 27.1 0.1 17 6.5 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Clathrin PF00637.20 KDO20860.1 - 2e-05 24.5 16.0 2.2 8.1 0.3 6.0 4 2 2 6 6 6 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KDO20860.1 - 0.00087 18.4 3.9 0.28 10.2 0.4 3.3 3 0 0 3 3 3 2 Coatomer WD associated region eIF2A PF08662.11 KDO20860.1 - 0.0013 18.6 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Mcl1_mid PF12341.8 KDO20860.1 - 0.0085 15.5 0.1 6.4 6.0 0.0 3.3 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region DUF2524 PF10732.9 KDO20860.1 - 0.052 13.9 0.5 0.16 12.3 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) TPR_14 PF13428.6 KDO20860.1 - 0.98 10.4 36.0 1.9 9.5 0.0 10.0 7 2 4 11 11 11 0 Tetratricopeptide repeat SbsC_C PF18058.1 KDO20860.1 - 1.5 9.1 9.4 0.29 11.3 2.5 2.5 2 0 0 2 2 2 0 SbsC C-terminal domain LRR_6 PF13516.6 KDO20861.1 - 5.1e-08 32.4 7.4 0.011 15.8 0.3 5.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KDO20861.1 - 3e-05 24.3 1.0 1.6 9.2 0.0 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO20861.1 - 0.014 15.1 8.7 3.3 7.5 0.9 5.6 4 2 0 4 4 4 0 Leucine rich repeat IQ PF00612.27 KDO20862.1 - 7.8e-08 31.5 23.8 0.0092 15.7 0.1 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA PF00004.29 KDO20863.1 - 1.1e-41 142.3 0.0 2e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KDO20863.1 - 2e-09 37.4 0.3 4.3e-09 36.3 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KDO20863.1 - 1.3e-08 34.5 0.0 4.1e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KDO20863.1 - 2.6e-06 27.4 0.0 1e-05 25.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KDO20863.1 - 2.4e-05 24.6 1.6 0.00025 21.3 0.6 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KDO20863.1 - 3.7e-05 23.5 0.0 9.9e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO20863.1 - 7e-05 22.8 0.3 0.00027 20.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO20863.1 - 0.0002 21.8 1.4 0.0008 19.8 0.3 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KDO20863.1 - 0.00059 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KDO20863.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KDO20863.1 - 0.0007 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KDO20863.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KDO20863.1 - 0.0035 16.8 0.1 0.0075 15.7 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KDO20863.1 - 0.0097 16.5 0.5 0.082 13.5 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO20863.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KDO20863.1 - 0.012 15.0 0.1 5.4 6.4 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 KDO20863.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO20863.1 - 0.014 15.3 0.1 0.057 13.3 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_25 PF13481.6 KDO20863.1 - 0.015 14.9 0.7 0.058 13.0 0.6 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KDO20863.1 - 0.021 14.5 0.0 0.59 9.8 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KDO20863.1 - 0.022 15.1 0.0 0.042 14.3 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KDO20863.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KDO20863.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KDO20863.1 - 0.043 13.2 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KDO20863.1 - 0.047 14.2 0.0 0.084 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KDO20863.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KDO20863.1 - 0.097 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KDO20863.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KDO20863.1 - 0.14 12.6 0.1 0.56 10.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KDO20863.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KDO20863.1 - 0.19 11.5 3.0 0.18 11.5 0.4 2.1 2 1 0 2 2 2 0 AAA domain EFP_N PF08207.12 KDO20864.1 - 7.4e-20 70.7 0.1 1.5e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 KDO20864.1 - 1.3e-15 57.2 0.2 2e-15 56.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Elong-fact-P_C PF09285.11 KDO20864.1 - 1.2e-08 34.6 0.9 2.5e-08 33.5 0.2 2.0 2 0 0 2 2 2 1 Elongation factor P, C-terminal Ribosomal_S4e PF00900.20 KDO20864.1 - 0.014 15.3 0.2 0.63 10.0 0.1 2.8 4 0 0 4 4 4 0 Ribosomal family S4e PP2C PF00481.21 KDO20865.1 - 8.5e-51 173.1 0.0 3.9e-48 164.3 0.0 2.4 1 1 1 2 2 2 2 Protein phosphatase 2C Pox_Ag35 PF03286.14 KDO20865.1 - 0.0012 18.6 6.0 0.003 17.4 6.0 1.6 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Toprim_Crpt PF13342.6 KDO20865.1 - 0.059 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase NOA36 PF06524.12 KDO20865.1 - 3.7 6.8 7.9 6.5 6.0 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein 2OG-FeII_Oxy_3 PF13640.6 KDO20866.1 - 2.7e-13 50.6 0.0 5.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GHMP_kinases_N PF00288.26 KDO20867.1 - 1.7e-13 50.6 1.3 6.7e-13 48.7 1.3 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KDO20867.1 - 3.3e-06 27.4 0.0 9.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal zf-Nse PF11789.8 KDO20868.1 - 7.1e-15 54.6 0.2 1.2e-14 53.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KDO20868.1 - 8.7e-05 22.3 0.1 0.00017 21.3 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO20868.1 - 0.0015 18.5 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 KDO20868.1 - 0.0019 18.3 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 KDO20868.1 - 0.0065 16.8 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.20 KDO20868.1 - 0.0076 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KDO20868.1 - 0.0093 16.2 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO20868.1 - 0.15 12.0 0.8 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CxC6 PF18721.1 KDO20869.1 - 0.01 16.1 24.8 1.3 9.3 0.1 3.6 1 1 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 KDO20870.1 - 1.7 8.9 30.4 4.7 7.6 0.2 4.2 1 1 3 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases TIM PF00121.18 KDO20871.1 - 2e-87 292.6 0.0 2.4e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Pyr_redox_2 PF07992.14 KDO20872.1 - 3.9e-48 164.2 0.0 5.2e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO20872.1 - 2.5e-22 79.2 0.0 4.8e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO20872.1 - 9.9e-17 61.3 2.2 7.5e-14 52.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO20872.1 - 1.1e-10 41.3 0.0 5.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KDO20872.1 - 4e-06 26.2 1.1 8.7e-06 25.1 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KDO20872.1 - 0.00025 20.4 0.1 0.058 12.7 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KDO20872.1 - 0.00031 20.9 2.8 0.022 15.0 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KDO20872.1 - 0.00031 20.2 0.2 0.00057 19.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO20872.1 - 0.0006 18.6 0.1 0.0012 17.6 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KDO20872.1 - 0.00075 18.8 1.5 0.0011 18.2 0.2 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KDO20872.1 - 0.0017 17.5 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KDO20872.1 - 0.0046 16.6 1.9 0.071 12.7 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KDO20872.1 - 0.029 14.8 0.1 1.9 9.0 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Amelotin PF15757.5 KDO20872.1 - 0.043 13.4 0.2 7.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Amelotin FAD_binding_3 PF01494.19 KDO20872.1 - 0.073 12.3 0.4 0.88 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain He_PIG PF05345.12 KDO20872.1 - 0.11 12.7 0.5 0.28 11.4 0.1 2.0 2 0 0 2 2 1 0 Putative Ig domain Lycopene_cycl PF05834.12 KDO20872.1 - 0.15 11.1 0.2 0.59 9.1 0.2 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein Indigoidine_A PF04227.12 KDO20873.1 - 2.2e-123 411.3 5.9 4e-123 410.4 5.9 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KDO20873.1 - 8.3e-25 87.7 2.9 6.9e-23 81.4 2.9 3.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Aha1_N PF09229.11 KDO20874.1 - 5.4e-23 81.7 0.1 1.1e-22 80.7 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal zf-MYND PF01753.18 KDO20874.1 - 3e-10 40.0 16.3 5.5e-10 39.2 16.3 1.5 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KDO20874.1 - 0.0031 15.4 6.7 0.0042 15.0 6.7 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 KDO20874.1 - 0.038 14.3 12.1 0.11 12.9 12.1 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_2 PF13347.6 KDO20875.1 - 1.4e-24 86.4 31.2 3.8e-19 68.6 7.9 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KDO20875.1 - 1.9e-15 56.7 29.4 2.3e-08 33.3 14.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO20875.1 - 0.055 12.3 29.8 0.018 13.9 11.2 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter AAA PF00004.29 KDO20878.1 - 7e-93 308.0 0.0 2.6e-49 167.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO20878.1 - 2.1e-25 88.2 0.6 5.1e-12 45.4 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KDO20878.1 - 3.9e-16 59.2 0.0 1.6e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KDO20878.1 - 6.2e-13 49.5 0.1 0.0012 19.2 0.2 4.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KDO20878.1 - 9e-12 45.4 0.0 5.4e-05 23.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KDO20878.1 - 3.4e-11 43.5 0.0 0.0001 22.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KDO20878.1 - 4.1e-11 43.0 1.1 0.00076 19.5 0.0 4.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO20878.1 - 1.5e-10 41.4 0.5 0.011 16.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 KDO20878.1 - 9.2e-09 35.0 0.4 0.0033 16.7 0.1 2.8 2 1 1 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KDO20878.1 - 3.1e-08 33.3 1.1 0.0047 16.3 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KDO20878.1 - 4.1e-08 33.3 0.0 0.0049 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KDO20878.1 - 4.2e-08 33.1 0.0 0.01 15.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KDO20878.1 - 1.2e-07 32.3 0.0 0.009 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KDO20878.1 - 1.8e-07 30.9 0.2 0.31 10.6 0.0 4.3 4 1 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 KDO20878.1 - 2.5e-07 31.1 0.0 0.014 15.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KDO20878.1 - 2.9e-07 30.9 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KDO20878.1 - 4e-07 30.1 0.8 0.024 14.6 0.0 3.1 3 0 0 3 3 2 2 NACHT domain ABC_tran PF00005.27 KDO20878.1 - 5.3e-07 30.2 0.2 0.043 14.3 0.0 3.4 3 1 1 4 4 3 2 ABC transporter TsaE PF02367.17 KDO20878.1 - 1.3e-06 28.4 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KDO20878.1 - 2.8e-06 27.2 0.1 0.094 12.4 0.1 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KDO20878.1 - 6e-06 26.1 0.1 0.098 12.3 0.0 3.2 4 0 0 4 4 3 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KDO20878.1 - 8.6e-06 25.0 0.2 0.061 12.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KDO20878.1 - 8.8e-06 25.1 0.2 0.033 13.4 0.0 3.1 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.22 KDO20878.1 - 3.3e-05 23.2 0.1 0.15 11.3 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activ_2 PF14532.6 KDO20878.1 - 3.9e-05 23.8 0.2 0.33 11.1 0.0 3.6 3 1 1 4 4 3 1 Sigma-54 interaction domain AAA_3 PF07726.11 KDO20878.1 - 6e-05 22.9 0.0 0.44 10.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO20878.1 - 0.00014 21.5 0.1 0.61 9.6 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KDO20878.1 - 0.00014 21.8 0.4 0.23 11.5 0.1 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 KDO20878.1 - 0.00015 21.8 0.1 0.06 13.3 0.0 3.4 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KDO20878.1 - 0.00025 21.0 0.0 0.055 13.4 0.0 2.9 2 1 1 3 3 3 1 Rad17 P-loop domain CPT PF07931.12 KDO20878.1 - 0.00046 20.1 0.0 0.088 12.6 0.0 2.6 3 0 0 3 3 2 1 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 KDO20878.1 - 0.00047 20.0 0.2 0.54 10.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 KDO20878.1 - 0.00049 19.5 0.2 1.2 8.5 0.0 2.8 2 1 0 3 3 3 2 KaiC AAA_17 PF13207.6 KDO20878.1 - 0.0005 20.5 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KDO20878.1 - 0.00086 19.1 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 KDO20878.1 - 0.0012 18.3 0.0 2.6 7.4 0.0 3.0 2 1 1 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 KDO20878.1 - 0.0026 17.2 1.2 2 7.8 0.1 2.7 3 0 0 3 3 2 1 PhoH-like protein DUF815 PF05673.13 KDO20878.1 - 0.0029 16.8 0.0 0.2 10.8 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 KDO20878.1 - 0.0039 16.9 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.9 KDO20878.1 - 0.005 16.1 0.0 0.7 9.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KDO20878.1 - 0.0055 17.1 0.9 6.3 7.1 0.2 2.9 2 1 0 3 3 2 0 AAA domain Hydin_ADK PF17213.3 KDO20878.1 - 0.0065 16.8 1.7 0.38 11.0 0.0 2.7 3 0 0 3 3 2 1 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 KDO20878.1 - 0.0076 16.0 0.7 1.6 8.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KDO20878.1 - 0.012 15.5 0.0 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KDO20878.1 - 0.014 14.3 0.1 0.59 9.0 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.9 KDO20878.1 - 0.016 15.0 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KDO20878.1 - 0.016 15.1 0.4 9 6.2 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 KDO20878.1 - 0.027 15.0 0.2 12 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 KDO20878.1 - 0.036 13.5 0.1 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 KDO20878.1 - 0.038 13.7 0.4 7.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Guanylate_kin PF00625.21 KDO20878.1 - 0.043 13.5 0.1 22 4.7 0.0 3.5 2 2 1 3 3 3 0 Guanylate kinase MMR_HSR1 PF01926.23 KDO20878.1 - 0.047 13.8 0.1 6.3 6.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cytidylate_kin2 PF13189.6 KDO20878.1 - 0.068 13.3 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.22 KDO20878.1 - 0.077 13.1 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 KDO20878.1 - 0.077 12.7 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.9 KDO20878.1 - 0.083 12.0 0.0 8.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zot PF05707.12 KDO20878.1 - 0.096 12.3 0.0 2.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) cobW PF02492.19 KDO20878.1 - 0.1 12.2 0.9 19 4.8 0.1 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KDO20878.1 - 0.1 11.6 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.18 KDO20878.1 - 0.12 11.9 0.3 9.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ResIII PF04851.15 KDO20878.1 - 0.13 12.2 0.0 6.7 6.7 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit PCI PF01399.27 KDO20879.1 - 1.7e-11 44.5 0.0 5.4e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 KDO20879.1 - 0.0075 15.9 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix C2 PF00168.30 KDO20881.1 - 2.1e-08 34.4 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain Peptidase_M76 PF09768.9 KDO20883.1 - 2.6e-27 95.7 2.8 3e-27 95.5 2.8 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KDO20883.1 - 0.023 14.5 0.1 0.044 13.6 0.1 1.6 1 1 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 KDO20883.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Effector protein Pox_G9-A16 PF03003.16 KDO20883.1 - 0.28 10.9 3.3 0.47 10.2 3.3 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 bZIP_1 PF00170.21 KDO20885.1 - 0.033 14.3 2.9 0.033 14.3 2.9 2.2 1 1 1 2 2 2 0 bZIP transcription factor Fe-ADH PF00465.19 KDO20888.1 - 6.5e-100 334.5 0.0 7.6e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KDO20888.1 - 7e-15 55.4 1.3 1.6e-10 41.1 0.1 2.9 2 1 1 3 3 3 2 Iron-containing alcohol dehydrogenase AglB_L1 PF18079.1 KDO20888.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain LRR_8 PF13855.6 KDO20889.1 - 2.5 7.9 7.3 0.38 10.5 0.4 3.2 4 0 0 4 4 4 0 Leucine rich repeat Pro_isomerase PF00160.21 KDO20890.1 - 1.4e-49 168.4 0.0 2.3e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 KDO20890.1 - 3e-28 98.0 0.0 8.7e-28 96.5 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KDO20890.1 - 1.2e-07 31.2 2.9 0.00043 20.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20890.1 - 3e-05 23.7 0.9 0.0091 15.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20890.1 - 3e-05 23.9 8.4 0.00056 19.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20890.1 - 0.00037 20.9 9.0 0.00064 20.2 3.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20890.1 - 0.0006 20.4 3.5 0.0006 20.4 3.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20890.1 - 0.0037 16.9 1.6 1.6 8.5 0.1 3.3 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 KDO20890.1 - 0.0062 16.7 1.2 0.014 15.5 1.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20890.1 - 0.012 16.3 5.4 0.073 13.9 0.7 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20890.1 - 0.042 14.2 3.3 0.11 13.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Chorion_S16 PF05836.12 KDO20890.1 - 7.5 6.8 8.0 0.58 10.4 2.0 2.4 2 1 0 2 2 2 0 Chorion protein S16 Kinesin PF00225.23 KDO20892.1 - 3e-95 318.9 0.2 5.1e-94 314.9 0.2 2.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO20892.1 - 6e-25 87.9 0.6 2.5e-24 85.9 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding MIP-T3 PF10243.9 KDO20892.1 - 2.8e-22 78.8 0.8 1.4e-21 76.6 0.1 2.5 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain F5_F8_type_C PF00754.25 KDO20892.1 - 4.3e-16 59.2 0.1 1.2e-08 35.2 0.0 3.4 3 0 0 3 3 3 2 F5/8 type C domain Seryl_tRNA_N PF02403.22 KDO20892.1 - 0.0053 17.0 8.2 0.0053 17.0 8.2 9.5 4 2 5 10 10 10 1 Seryl-tRNA synthetase N-terminal domain AAA_22 PF13401.6 KDO20892.1 - 0.029 14.7 5.5 2.1 8.6 0.0 3.7 2 1 1 3 3 3 0 AAA domain Tctex-1 PF03645.13 KDO20893.1 - 3.7e-24 84.9 0.1 4.2e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family LRR_6 PF13516.6 KDO20894.1 - 0.00078 19.3 7.5 0.059 13.5 0.2 4.5 4 0 0 4 4 4 2 Leucine Rich repeat SecB PF02556.14 KDO20894.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit SecB LRR_8 PF13855.6 KDO20894.1 - 0.12 12.2 5.5 0.15 11.9 1.4 3.2 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KDO20894.1 - 0.16 12.4 4.3 1.5 9.3 0.1 3.5 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) CH_2 PF06294.11 KDO20895.1 - 6e-17 61.5 0.0 1.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 KDO20895.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain ADK PF00406.22 KDO20896.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase Myb_DNA-binding PF00249.31 KDO20897.1 - 2.3e-33 114.1 0.1 7.3e-10 38.9 0.0 5.9 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20897.1 - 1.7e-32 111.4 0.0 9.9e-14 51.3 0.0 5.3 5 0 0 5 5 5 4 Myb-like DNA-binding domain Rap1_C PF11626.8 KDO20897.1 - 0.00016 21.7 0.1 0.013 15.6 0.1 3.3 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KDO20897.1 - 0.0076 16.5 1.2 2.4 8.6 0.0 3.4 3 1 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 KDO20897.1 - 0.026 14.7 0.2 1.6 9.0 0.0 3.5 3 1 0 3 3 3 0 Rap1 Myb domain Atg29_N PF18388.1 KDO20897.1 - 0.69 9.8 3.3 15 5.5 0.0 3.7 4 0 0 4 4 4 0 Atg29 N-terminal domain Myb_DNA-binding PF00249.31 KDO20898.1 - 5.2e-06 26.6 0.4 0.033 14.4 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO20898.1 - 0.0073 16.5 0.0 0.63 10.3 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain gag-asp_proteas PF13975.6 KDO20898.1 - 0.15 12.6 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease LRR_6 PF13516.6 KDO20899.1 - 2.8e-14 51.9 3.2 0.0048 16.9 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 KDO20899.1 - 0.00026 20.7 4.5 7.1 6.5 0.1 5.0 3 2 1 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 KDO20899.1 - 0.013 15.9 1.5 5.1 7.6 0.0 4.0 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) RRN3 PF05327.11 KDO20899.1 - 0.54 8.7 10.1 0.69 8.4 10.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM104 PF15434.6 KDO20899.1 - 4.1 8.0 7.8 9.2 6.9 7.8 1.6 1 0 0 1 1 1 0 Family 104 DNA_pol_phi PF04931.13 KDO20899.1 - 7.5 4.5 15.6 11 3.9 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Myticin-prepro PF10690.9 KDO20901.1 - 0.024 14.9 1.2 0.024 14.9 1.2 2.6 2 1 1 3 3 3 0 Myticin pre-proprotein from the mussel Meiosis_expr PF15163.6 KDO20902.1 - 2.3e-26 92.2 7.3 3.2e-26 91.8 7.3 1.2 1 0 0 1 1 1 1 Meiosis-expressed TPR_2 PF07719.17 KDO20903.1 - 1.6e-07 30.9 10.4 0.00037 20.4 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20903.1 - 2.3e-07 31.0 5.3 2.1e-05 25.0 0.8 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20903.1 - 4.3e-07 29.6 1.3 0.013 15.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20903.1 - 1.8e-06 27.5 12.4 0.0046 16.7 0.2 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20903.1 - 2.3e-05 24.9 8.2 0.0012 19.5 0.7 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO20903.1 - 2.9e-05 24.1 3.8 0.02 15.1 0.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO20903.1 - 0.00014 21.5 5.8 1.4 8.6 0.1 3.6 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 KDO20903.1 - 0.00025 21.5 9.7 0.00062 20.2 3.5 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO20903.1 - 0.00056 20.4 6.3 0.13 13.0 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20903.1 - 0.00076 19.3 7.0 0.013 15.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20903.1 - 0.0012 19.0 4.1 0.074 13.5 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO20903.1 - 0.005 17.0 1.0 0.005 17.0 1.0 2.2 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3844 PF12955.7 KDO20903.1 - 0.052 13.7 0.0 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DUF3209 PF11483.8 KDO20903.1 - 0.069 13.6 0.9 0.33 11.4 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) TPR_12 PF13424.6 KDO20903.1 - 0.41 11.0 7.2 1.2 9.4 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-primase PF09329.11 KDO20904.1 - 8.6e-10 38.3 0.3 1.5e-09 37.5 0.3 1.4 1 0 0 1 1 1 1 Primase zinc finger EspG PF06872.11 KDO20904.1 - 0.053 12.1 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 EspG protein Glyco_transf_41 PF13844.6 KDO20905.1 - 9.5e-80 268.3 0.0 1.7e-41 142.2 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferase family 41 Methyltransf_11 PF08241.12 KDO20905.1 - 1.8e-05 25.3 0.0 5.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_16 PF13432.6 KDO20905.1 - 0.00038 21.1 0.2 0.00038 21.1 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20905.1 - 0.0054 16.7 0.0 3.8 7.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20905.1 - 0.03 14.1 0.1 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 KDO20905.1 - 0.048 13.5 0.2 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TPR_14 PF13428.6 KDO20905.1 - 0.73 10.8 0.0 0.73 10.8 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO20905.1 - 2.8 8.3 6.4 2.6 8.4 0.6 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1765 PF08578.10 KDO20906.1 - 2.3e-20 73.3 2.1 2.3e-20 73.3 2.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) PH PF00169.29 KDO20906.1 - 4.6e-10 39.9 0.2 4.4e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 PH domain C2 PF00168.30 KDO20906.1 - 2.1e-09 37.6 0.0 6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF1825 PF08855.10 KDO20906.1 - 0.0085 16.0 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) Ras PF00071.22 KDO20907.1 - 3.1e-16 59.4 0.0 4.2e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO20907.1 - 4.3e-13 49.5 0.0 1.7e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO20907.1 - 1.4e-07 31.1 0.0 4e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO20907.1 - 5.3e-07 29.7 0.0 7.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KDO20907.1 - 0.0034 16.8 0.0 0.0055 16.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KDO20907.1 - 0.0068 16.3 0.1 0.062 13.2 0.1 2.2 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KDO20907.1 - 0.009 15.6 0.0 0.26 10.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KDO20907.1 - 0.014 15.7 0.1 0.024 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KDO20907.1 - 0.07 13.6 0.1 0.12 12.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter DUF4381 PF14316.6 KDO20908.1 - 1.3e-05 25.5 0.1 2.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KDO20908.1 - 0.0034 18.2 0.8 0.0093 16.8 0.8 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KDO20908.1 - 0.0061 16.5 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 TMEM154 protein family WBP-1 PF11669.8 KDO20908.1 - 0.0072 16.9 3.5 0.023 15.3 3.5 1.8 1 1 0 1 1 1 1 WW domain-binding protein 1 Rhabdo_glycop PF00974.18 KDO20908.1 - 0.024 13.1 0.3 0.047 12.2 0.3 1.4 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF4446 PF14584.6 KDO20908.1 - 0.028 14.4 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Phage_Gp23 PF10669.9 KDO20908.1 - 0.038 14.3 0.3 0.074 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) OATP PF03137.20 KDO20908.1 - 0.071 11.4 0.2 0.094 11.0 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TMIE PF16038.5 KDO20908.1 - 0.092 12.6 5.2 0.22 11.4 3.5 2.1 2 1 0 2 2 2 0 TMIE protein TRAP_alpha PF03896.16 KDO20908.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TMEM52 PF14979.6 KDO20908.1 - 0.15 12.0 0.5 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 Transmembrane 52 TMEM51 PF15345.6 KDO20908.1 - 0.24 11.2 3.8 0.86 9.4 3.8 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 Insulin_TMD PF17870.1 KDO20908.1 - 0.32 11.1 1.7 0.55 10.3 1.7 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Thymidylate_kin PF02223.17 KDO20908.1 - 0.39 10.4 2.3 0.63 9.7 2.3 1.3 1 0 0 1 1 1 0 Thymidylate kinase TERB2 PF15101.6 KDO20908.1 - 1.7 8.6 5.7 2.5 8.1 5.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 XhlA PF10779.9 KDO20908.1 - 6.4 7.1 5.1 16 5.8 5.1 1.6 1 0 0 1 1 1 0 Haemolysin XhlA RCR PF12273.8 KDO20908.1 - 6.9 7.4 13.4 34 5.1 13.4 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pyridoxal_deC PF00282.19 KDO20909.1 - 0.02 13.6 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF521 PF04412.13 KDO20909.1 - 0.24 10.1 0.0 0.51 9.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF521) DUF4419 PF14388.6 KDO20910.1 - 6.6e-101 337.7 0.0 7.7e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Succ_CoA_lig PF13607.6 KDO20910.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain YndJ PF14158.6 KDO20910.1 - 0.096 12.0 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 YndJ-like protein AA_permease_2 PF13520.6 KDO20911.1 - 2.3e-17 63.0 31.5 1.5e-12 47.1 10.6 2.7 2 1 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 KDO20911.1 - 7.2e-11 42.0 1.2 7.2e-11 42.0 1.2 3.5 5 1 0 5 5 5 1 C-terminus of AA_permease AA_permease PF00324.21 KDO20911.1 - 6.3e-10 38.2 28.4 2.9e-08 32.8 12.0 2.3 1 1 1 2 2 2 2 Amino acid permease DUF4006 PF13179.6 KDO20911.1 - 0.29 11.1 0.2 0.29 11.1 0.2 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF4006) AA_permease_2 PF13520.6 KDO20912.1 - 2.5e-39 135.3 37.7 2.5e-39 135.3 37.7 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO20912.1 - 7e-28 97.5 35.9 1e-27 96.9 35.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KDO20912.1 - 2.8e-13 49.7 1.3 2.8e-13 49.7 1.3 3.2 3 0 0 3 3 3 1 C-terminus of AA_permease EptA_B_N PF08019.12 KDO20912.1 - 6 6.7 17.8 3.6 7.4 5.5 2.9 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB AA_permease_2 PF13520.6 KDO20913.1 - 2e-38 132.3 43.8 2.5e-37 128.7 43.8 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO20913.1 - 2.6e-31 108.8 35.0 4.3e-31 108.0 35.0 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KDO20913.1 - 7.9e-13 48.3 4.4 7.9e-13 48.3 4.4 3.3 5 0 0 5 5 5 1 C-terminus of AA_permease IQ PF00612.27 KDO20914.1 - 1.5e-10 39.9 94.7 0.062 13.1 0.1 15.5 15 0 0 15 15 15 12 IQ calmodulin-binding motif WW PF00397.26 KDO20914.1 - 6.9e-06 26.0 0.9 1.9e-05 24.6 0.9 1.8 1 0 0 1 1 1 1 WW domain RRP7 PF12923.7 KDO20915.1 - 8.3e-24 84.0 17.2 1.2e-23 83.5 17.2 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KDO20915.1 - 0.00043 20.1 0.0 0.00064 19.5 0.0 1.7 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 KDO20915.1 - 0.013 15.8 0.2 0.055 13.8 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) RRM_1 PF00076.22 KDO20915.1 - 0.078 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L7Ae PF01248.26 KDO20916.1 - 6.3e-25 86.7 0.0 7.4e-25 86.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family BiPBP_C PF06832.12 KDO20917.1 - 0.00057 19.9 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family zf-HC5HC2H_2 PF13832.6 KDO20918.1 - 1.9e-29 102.0 6.9 6e-27 94.0 0.2 2.3 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO20918.1 - 2.7e-21 75.6 8.2 1.6e-18 66.8 0.0 3.1 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 KDO20918.1 - 1e-06 28.5 17.5 5.1e-06 26.3 8.1 3.1 3 1 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 KDO20918.1 - 6.8e-05 22.3 1.4 6.8e-05 22.3 1.4 3.0 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.11 KDO20918.1 - 7.8e-05 22.9 18.0 0.019 15.3 2.5 2.7 2 0 0 2 2 2 2 RING-like domain BET PF17035.5 KDO20918.1 - 0.00011 22.3 0.1 0.023 14.9 0.2 2.5 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Prok-RING_1 PF14446.6 KDO20918.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KDO20918.1 - 2.9 8.2 17.9 0.88 9.8 0.7 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain Ribosomal_S2 PF00318.20 KDO20919.1 - 2.2e-26 92.5 0.1 4.4e-13 49.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KDO20919.1 - 0.0082 17.5 18.8 0.025 15.9 18.8 1.9 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus LMWPc PF01451.21 KDO20920.1 - 2.4e-20 73.4 0.1 4.3e-19 69.3 0.1 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Globin PF00042.22 KDO20921.1 - 0.071 13.7 0.3 0.28 11.7 0.3 2.0 1 1 0 1 1 1 0 Globin Pkinase_Tyr PF07714.17 KDO20922.1 - 4.3e-20 72.1 0.0 6.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20922.1 - 4e-17 62.4 0.0 6.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KDO20922.1 - 6.4e-08 33.0 0.8 4.3e-05 24.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20922.1 - 1.5e-07 31.5 0.3 6.7e-07 29.5 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20922.1 - 1.2e-06 29.0 0.1 2.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO20922.1 - 1.8e-05 24.7 0.2 0.0031 17.9 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KDO20922.1 - 0.072 13.6 0.6 2.5 8.7 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeat zinc-ribbons_6 PF07191.12 KDO20922.1 - 7.7 6.6 8.7 19 5.3 5.5 2.6 1 1 1 2 2 2 0 zinc-ribbons Pkinase_Tyr PF07714.17 KDO20923.1 - 3.5e-38 131.4 0.0 4.3e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO20923.1 - 3.4e-37 128.2 0.0 4.5e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3678 PF12435.8 KDO20923.1 - 0.0025 17.1 1.9 0.0025 17.1 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3678) Kdo PF06293.14 KDO20923.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO20923.1 - 0.042 12.9 0.1 0.063 12.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_5 PF13857.6 KDO20924.1 - 3.5e-17 62.2 0.8 1.9e-09 37.6 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20924.1 - 7.8e-16 58.4 0.1 1.7e-14 54.1 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20924.1 - 1.2e-12 48.0 0.7 0.00019 21.9 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO20924.1 - 2.2e-12 46.8 0.5 1.9e-05 24.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO20924.1 - 3.3e-11 42.4 0.1 0.005 17.2 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Peptidase_C39_2 PF13529.6 KDO20924.1 - 0.19 12.2 0.0 0.28 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Ank_2 PF12796.7 KDO20925.1 - 1.9e-52 175.8 35.9 2.1e-11 44.3 0.2 5.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO20925.1 - 2.3e-37 128.8 0.0 1.1e-36 126.6 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Ank_4 PF13637.6 KDO20925.1 - 8.2e-37 125.1 9.2 1.8e-08 34.7 0.0 7.6 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO20925.1 - 2.9e-31 108.7 0.0 3.5e-30 105.2 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Ank_3 PF13606.6 KDO20925.1 - 3e-28 94.7 9.2 0.0019 18.5 0.1 11.5 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 KDO20925.1 - 8.4e-15 54.6 20.8 0.054 13.8 0.1 8.8 3 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO20925.1 - 3.2e-10 40.0 36.6 0.2 12.2 0.0 11.5 12 0 0 12 12 12 4 Ankyrin repeat Kdo PF06293.14 KDO20925.1 - 0.0046 16.3 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO20925.1 - 0.019 13.8 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FlgD_ig PF13860.6 KDO20925.1 - 1.5 8.8 4.2 0.67 9.9 1.3 1.9 2 0 0 2 2 2 0 FlgD Ig-like domain Sterol_MT_C PF08498.10 KDO20925.1 - 5.7 7.3 7.1 7.4 7.0 0.3 3.4 3 0 0 3 3 3 0 Sterol methyltransferase C-terminal FAM183 PF14886.6 KDO20927.1 - 1.9e-06 28.5 0.1 2.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related FHA PF00498.26 KDO20928.1 - 4.5e-08 33.3 0.0 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 2 FHA domain HA PF03457.14 KDO20929.1 - 3.7e-38 129.7 0.5 8.2e-11 42.1 0.1 5.2 5 0 0 5 5 5 5 Helicase associated domain Ribosomal_L30 PF00327.20 KDO20929.1 - 0.041 13.8 0.2 0.31 10.9 0.1 2.5 3 0 0 3 3 3 0 Ribosomal protein L30p/L7e Metal_resist PF13801.6 KDO20929.1 - 0.084 13.1 0.2 8.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Heavy-metal resistance Sod_Cu PF00080.20 KDO20930.1 - 8.2e-37 126.5 1.9 1e-36 126.2 1.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Elicitin PF00964.17 KDO20931.1 - 1.2e-11 44.6 0.3 1.6e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO20932.1 - 1.2e-08 34.9 1.8 1.5e-08 34.6 1.0 1.7 1 1 0 1 1 1 1 Elicitin Adhesin_P1 PF03257.13 KDO20932.1 - 0.029 14.9 0.4 0.029 14.9 0.4 1.8 2 0 0 2 2 2 0 Mycoplasma adhesin P1 PLAC8 PF04749.17 KDO20933.1 - 1.1e-13 52.0 16.2 5.5e-11 43.3 5.5 2.2 1 1 1 2 2 2 2 PLAC8 family IQ PF00612.27 KDO20934.1 - 1 9.4 19.2 0.21 11.5 0.4 4.7 4 0 0 4 4 4 0 IQ calmodulin-binding motif zf-UBR PF02207.20 KDO20935.1 - 4e-15 55.7 15.9 4e-15 55.7 15.9 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) FHA PF00498.26 KDO20936.1 - 7.9e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO20936.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Sugar_tr PF00083.24 KDO20937.1 - 2.6e-36 125.5 17.4 3.5e-36 125.0 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO20937.1 - 3.7e-35 121.5 27.8 1.4e-23 83.4 15.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KDO20937.1 - 0.09 12.1 20.6 0.038 13.3 5.2 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Gly-zipper_Omp PF13488.6 KDO20937.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 Glycine zipper Zip PF02535.22 KDO20938.1 - 1.8e-42 145.8 13.8 1.9e-41 142.4 13.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.12 KDO20938.1 - 1.3 8.5 10.7 1.3 8.4 4.9 2.3 2 0 0 2 2 2 0 HupE / UreJ protein DUF4381 PF14316.6 KDO20939.1 - 0.23 11.7 0.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1664 PF07889.12 KDO20940.1 - 0.68 10.0 22.1 1.5 8.9 0.7 5.2 3 1 2 6 6 6 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KDO20940.1 - 2.7 8.4 11.9 27 5.2 0.0 6.2 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) CCDC53 PF10152.9 KDO20940.1 - 6.6 7.1 10.2 16 5.9 2.2 3.1 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex NPV_P10 PF05531.12 KDO20940.1 - 7.8 7.0 14.4 6.7 7.3 3.5 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Elicitin PF00964.17 KDO20943.1 - 0.0029 17.7 2.7 0.0053 16.8 2.6 1.5 1 1 0 1 1 1 1 Elicitin Arrestin_N PF00339.29 KDO20944.1 - 1.3e-20 73.9 0.3 1.7e-17 63.9 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KDO20944.1 - 2.8e-15 56.9 0.0 2.6e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KDO20944.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Rgp1 PF08737.10 KDO20944.1 - 0.042 13.0 0.8 5.5 6.0 0.0 2.2 1 1 1 2 2 2 0 Rgp1 Elicitin PF00964.17 KDO20945.1 - 0.00061 19.8 1.8 0.00061 19.8 1.8 2.0 1 1 0 1 1 1 1 Elicitin TENA_THI-4 PF03070.16 KDO20945.1 - 0.071 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Syndecan PF01034.20 KDO20946.1 - 0.00041 20.2 0.1 0.00089 19.1 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain DUF3283 PF11686.8 KDO20946.1 - 0.0052 16.6 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3283) DUF2681 PF10883.8 KDO20946.1 - 0.065 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) MtrF PF09472.10 KDO20946.1 - 1 8.8 3.6 2.6 7.5 3.6 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ank_2 PF12796.7 KDO20947.1 - 1e-28 99.7 4.1 5.1e-09 36.6 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20947.1 - 2.7e-21 75.6 4.3 3.1e-08 34.0 0.0 5.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) PDZ_6 PF17820.1 KDO20947.1 - 3.1e-18 65.4 12.3 0.0073 16.1 0.4 6.2 5 1 0 5 5 5 5 PDZ domain Ank_5 PF13857.6 KDO20947.1 - 2.7e-14 53.0 7.7 3.9e-05 23.8 0.0 6.0 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20947.1 - 2e-13 49.2 3.2 0.0023 18.2 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat PDZ_2 PF13180.6 KDO20947.1 - 3.3e-12 46.5 0.0 0.032 14.6 0.1 5.5 5 0 0 5 5 5 2 PDZ domain Ank PF00023.30 KDO20947.1 - 9.3e-10 38.5 6.2 0.0011 19.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat PDZ PF00595.24 KDO20947.1 - 5.6e-08 33.0 0.0 1.5 9.2 0.0 5.4 5 0 0 5 5 5 2 PDZ domain GRASP55_65 PF04495.14 KDO20947.1 - 8.4e-08 32.6 0.0 0.0072 16.6 0.0 3.7 3 0 0 3 3 3 2 GRASP55/65 PDZ-like domain Pkinase PF00069.25 KDO20949.1 - 9e-49 166.2 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20949.1 - 4.2e-28 98.3 0.0 5.6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO20949.1 - 0.00022 20.7 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO20949.1 - 0.00087 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO20949.1 - 0.0013 17.8 0.4 0.002 17.1 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO20949.1 - 0.0069 15.2 0.1 0.0077 15.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO20949.1 - 0.014 15.3 0.3 0.014 15.3 0.3 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF4407 PF14362.6 KDO20952.1 - 0.067 12.5 6.9 0.12 11.7 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KDO20952.1 - 0.086 12.9 5.0 0.17 12.0 5.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 KDO20952.1 - 1.2 10.1 6.4 1.2 10.1 4.4 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Filament PF00038.21 KDO20954.1 - 1.5e-20 74.0 58.0 1.9e-20 73.7 58.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KDO20954.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain DUF4168 PF13767.6 KDO20954.1 - 0.001 20.2 6.6 0.001 20.2 6.6 4.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4168) Fib_alpha PF08702.10 KDO20954.1 - 0.0095 16.1 5.3 0.0095 16.1 5.3 3.0 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family CCDC92 PF14916.6 KDO20954.1 - 0.042 13.6 0.5 0.042 13.6 0.5 3.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function TPR_MLP1_2 PF07926.12 KDO20954.1 - 0.41 10.7 60.5 0.81 9.7 21.5 4.8 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KDO20954.1 - 2.5 8.2 24.6 1.4 8.9 3.9 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KDO20954.1 - 6 6.2 57.6 1.3 8.4 25.7 3.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 KDO20954.1 - 7.1 6.9 33.5 0.21 11.9 8.9 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) Par3_HAL_N_term PF12053.8 KDO20955.1 - 1.8e-06 28.1 0.0 2.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins PolyA_pol PF01743.20 KDO20956.1 - 8.6e-23 81.1 0.0 1.6e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KDO20956.1 - 5.7e-07 29.2 0.0 1.6e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DHHC PF01529.20 KDO20957.1 - 1.9e-24 86.3 4.0 1.9e-24 86.3 4.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Disintegrin PF00200.23 KDO20958.1 - 1.2 9.9 44.8 2.3 9.1 1.7 3.9 1 1 2 3 3 3 0 Disintegrin Disintegrin PF00200.23 KDO20959.1 - 3.3e-09 37.4 105.6 2.3e-06 28.3 13.4 8.9 3 3 4 7 7 7 4 Disintegrin Disintegrin PF00200.23 KDO20960.1 - 4.9e-07 30.4 43.7 7e-05 23.5 13.0 4.7 2 2 1 4 4 4 3 Disintegrin NDUFV3 PF15880.5 KDO20962.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial PIP5K PF01504.18 KDO20963.1 - 4.8e-71 239.2 0.0 8.8e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 KDO20963.1 - 0.00011 21.7 8.3 0.00011 21.7 8.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-BED PF02892.15 KDO20963.1 - 0.092 12.8 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger 7tm_1 PF00001.21 KDO20963.1 - 0.81 9.0 5.7 0.14 11.5 1.5 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF3523 PF12037.8 KDO20964.1 - 2.2e-41 142.0 18.4 3.3e-41 141.4 18.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KDO20964.1 - 2.7e-21 76.4 0.0 8.9e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO20964.1 - 1.2e-05 25.2 0.0 3.2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KDO20964.1 - 3.9e-05 23.9 0.6 0.0049 17.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KDO20964.1 - 9.6e-05 21.9 0.1 0.00023 20.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO20964.1 - 0.00026 21.0 0.2 0.0024 17.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KDO20964.1 - 0.0033 17.0 3.5 0.21 11.1 0.0 3.1 2 2 1 3 3 3 1 AAA domain MRF_C1 PF13887.6 KDO20964.1 - 0.0047 16.0 0.0 0.017 14.3 0.0 2.0 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Zot PF05707.12 KDO20964.1 - 0.0048 16.6 0.6 0.2 11.3 0.0 3.0 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 KDO20964.1 - 0.0049 17.3 11.8 0.0083 16.5 0.0 3.7 2 2 1 3 3 2 1 AAA ATPase domain AAA_3 PF07726.11 KDO20964.1 - 0.0092 15.8 0.0 0.037 13.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO20964.1 - 0.0097 16.5 0.4 0.078 13.5 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KDO20964.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KDO20964.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KDO20964.1 - 0.055 13.5 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO20964.1 - 0.2 12.1 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KDO20964.1 - 0.21 12.0 0.2 0.21 12.0 0.2 3.4 3 1 1 5 5 4 0 AAA domain AAA_11 PF13086.6 KDO20964.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.7 2 1 0 2 2 1 0 AAA domain DUF2259 PF10016.9 KDO20964.1 - 1.5 8.7 8.1 8.2 6.3 7.2 2.3 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) 2OG-FeII_Oxy_3 PF13640.6 KDO20965.1 - 1.1e-15 58.2 0.0 2.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KDO20966.1 - 6.7e-14 52.6 0.0 1.4e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M14 PF00246.24 KDO20967.1 - 7.4e-37 127.7 0.0 9.3e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Aminotran_5 PF00266.19 KDO20968.1 - 6.9e-14 51.6 0.0 9.1e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KDO20968.1 - 0.00013 20.7 0.0 0.00019 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2154 PF09922.9 KDO20969.1 - 0.00013 21.8 0.1 0.00028 20.7 0.1 1.5 1 1 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF VPS9 PF02204.18 KDO20970.1 - 0.00033 20.8 0.0 0.00064 19.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Adeno_E3 PF06040.11 KDO20972.1 - 0.076 13.2 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3 protein NitrOD5 PF11537.8 KDO20974.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 GNAT_C PF18164.1 KDO20974.1 - 0.046 13.4 0.1 0.56 9.9 0.1 2.3 2 0 0 2 2 2 0 GNAT-like C-terminal domain T2SSJ PF11612.8 KDO20974.1 - 0.14 12.3 0.0 9 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J Pkinase PF00069.25 KDO20975.1 - 4.7e-29 101.6 0.0 6.8e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20975.1 - 8.3e-27 94.1 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KDO20975.1 - 1.6e-10 41.4 0.5 3.5e-07 30.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO20975.1 - 1.2e-05 25.6 2.7 0.015 15.7 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KDO20975.1 - 3.7e-05 23.8 2.5 0.0069 16.8 0.1 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KDO20975.1 - 5.4e-05 23.4 4.2 0.0014 18.9 0.2 3.7 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO20975.1 - 0.00012 22.5 2.8 0.0031 18.0 0.1 4.1 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Kinase-like PF14531.6 KDO20975.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ank_2 PF12796.7 KDO20976.1 - 1.4e-47 160.1 14.0 1.4e-11 44.8 0.1 7.3 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO20976.1 - 2.1e-40 138.7 0.0 3.2e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KDO20976.1 - 5.5e-39 132.1 15.3 1.1e-05 25.9 0.0 8.9 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO20976.1 - 1.2e-37 129.6 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KDO20976.1 - 2.4e-29 101.0 19.7 3.2e-10 40.1 0.2 9.2 5 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20976.1 - 5.7e-29 96.9 10.8 0.0051 17.2 0.1 13.2 13 1 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 KDO20976.1 - 6.5e-26 89.6 26.7 8e-06 26.1 0.1 12.0 13 0 0 13 13 13 6 Ankyrin repeat Pkinase_fungal PF17667.1 KDO20976.1 - 2.7e-05 23.1 0.1 0.00024 20.0 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 KDO20976.1 - 0.048 13.3 0.0 0.35 10.5 0.0 2.2 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO20976.1 - 1 9.3 10.1 3.1 7.7 0.8 4.5 4 1 1 5 5 5 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO20977.1 - 4.5e-32 111.5 0.0 5.3e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20977.1 - 3.6e-31 108.4 0.0 4.1e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO20977.1 - 0.051 12.9 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KDO20978.1 - 3.8e-24 85.4 0.0 7e-14 51.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO20978.1 - 1.2e-17 64.2 0.0 1.8e-11 43.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 KDO20978.1 - 8.8e-10 39.1 0.2 4.9e-07 30.2 0.0 2.7 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20978.1 - 1.1e-06 29.0 1.2 0.0053 17.3 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20978.1 - 7.3e-06 26.2 3.7 0.0015 18.8 0.1 4.2 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20978.1 - 2e-05 24.6 1.4 0.0068 16.8 0.1 4.7 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 KDO20978.1 - 6.6e-05 23.2 1.4 0.014 15.8 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat DUF4936 PF16290.5 KDO20978.1 - 0.09 13.5 0.5 0.92 10.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) Gemin6 PF06372.12 KDO20978.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Gemin6 protein Ank_2 PF12796.7 KDO20979.1 - 2.5e-57 191.4 25.7 1.2e-17 64.2 0.3 7.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20979.1 - 1e-47 159.9 21.2 3.8e-11 43.3 0.1 9.6 4 2 6 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO20979.1 - 1.4e-43 146.3 28.5 1.8e-13 50.4 1.0 12.1 5 3 8 13 13 13 12 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO20979.1 - 9.1e-43 146.4 0.0 2e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KDO20979.1 - 7.6e-41 136.8 35.0 2.4e-08 34.0 0.9 12.7 12 1 1 13 13 13 9 Ankyrin repeat Pkinase PF00069.25 KDO20979.1 - 1.2e-40 139.5 0.0 3.3e-40 138.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KDO20979.1 - 8.6e-38 124.1 14.3 3.2e-05 24.0 0.0 12.5 12 0 0 12 12 12 8 Ankyrin repeat Kinase-like PF14531.6 KDO20979.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Kinase-like GATase_7 PF13537.6 KDO20979.1 - 0.094 12.6 0.3 2.2 8.2 0.0 3.5 4 1 1 5 5 5 0 Glutamine amidotransferase domain Ank_2 PF12796.7 KDO20980.1 - 1.2e-45 153.9 21.0 2.3e-09 37.7 0.4 7.5 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO20980.1 - 4.9e-40 135.4 9.5 3.1e-11 43.6 0.0 7.4 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO20980.1 - 6.5e-38 130.6 0.0 1.2e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20980.1 - 6.2e-37 127.3 0.0 2.7e-36 125.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_5 PF13857.6 KDO20980.1 - 2.1e-35 120.3 18.0 6.7e-12 45.4 0.4 10.3 6 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20980.1 - 3.2e-35 116.2 6.6 1.1e-05 25.4 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 KDO20980.1 - 3e-33 112.8 18.1 1.7e-06 28.2 0.1 9.8 9 0 0 9 9 9 7 Ankyrin repeat Kinase-like PF14531.6 KDO20980.1 - 0.0053 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Kinase-like EF-hand_7 PF13499.6 KDO20981.1 - 4.1e-10 40.0 5.0 9e-05 22.8 0.3 5.2 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO20981.1 - 9.1e-07 28.3 1.0 0.23 11.5 0.7 6.7 6 0 0 6 6 6 1 EF-hand domain EF-hand_8 PF13833.6 KDO20981.1 - 2.2e-05 24.2 0.0 1.6 8.6 0.3 4.8 7 0 0 7 7 7 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO20981.1 - 0.0014 18.0 3.1 0.31 10.7 0.7 4.5 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.6 KDO20981.1 - 0.034 14.5 0.1 24 5.3 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain DUF3349 PF11829.8 KDO20981.1 - 0.054 14.3 0.0 6 7.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) TPR_12 PF13424.6 KDO20982.1 - 7e-19 67.9 14.7 0.00012 22.3 1.0 5.5 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20982.1 - 1.1e-15 56.9 12.9 0.014 15.2 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20982.1 - 2.8e-12 45.7 0.8 0.00021 21.2 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20982.1 - 3.3e-10 39.3 0.1 0.00045 19.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO20982.1 - 6.9e-09 35.2 0.2 0.005 17.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20982.1 - 3.7e-05 23.4 0.5 0.31 11.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO20982.1 - 0.008 16.8 0.7 2.1 9.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO20982.1 - 0.0094 16.6 3.8 11 6.8 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO20982.1 - 0.012 15.9 0.8 0.13 12.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO20982.1 - 0.31 11.8 7.5 23 6.0 0.0 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO20982.1 - 0.65 11.0 8.4 12 7.0 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat DZR PF12773.7 KDO20982.1 - 8.5 6.5 7.6 17 5.6 7.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 KDO20983.1 - 9.8e-30 103.8 0.0 1.5e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO20983.1 - 1.1e-29 103.6 0.0 1.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO20983.1 - 0.19 11.0 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ank_4 PF13637.6 KDO20984.1 - 3.1e-23 81.8 28.4 1.1e-06 29.0 0.7 6.9 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO20984.1 - 5e-22 78.3 9.0 1e-07 32.5 0.3 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO20984.1 - 3e-20 72.0 17.5 0.0071 16.6 0.2 8.9 1 1 8 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO20984.1 - 7.5e-11 41.3 11.7 0.41 11.4 0.2 9.4 8 2 2 10 10 10 2 Ankyrin repeat Ank PF00023.30 KDO20984.1 - 9.6e-05 22.7 13.0 37 5.0 0.1 8.2 3 2 3 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 KDO20984.1 - 0.0033 17.3 2.2 25 4.9 0.0 5.7 5 2 3 8 8 8 0 Domain of unknown function (DUF5049) Vps23_core PF09454.10 KDO20984.1 - 0.0034 17.3 0.0 0.55 10.2 0.0 4.1 6 0 0 6 6 6 1 Vps23 core domain DUF1707 PF08044.11 KDO20984.1 - 0.019 15.0 10.5 5.6 7.1 0.1 5.8 4 2 1 5 5 5 0 Domain of unknown function (DUF1707) PT PF04886.12 KDO20985.1 - 2.1e-45 151.9 125.4 1.9e-07 30.5 17.0 8.2 2 2 3 5 5 5 5 PT repeat CAP PF00188.26 KDO20985.1 - 1.7e-09 38.6 0.3 2.9e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KDO20986.1 - 8.4e-10 39.6 0.7 1.4e-09 38.8 0.1 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 KDO20989.1 - 4.6e-08 33.9 0.7 1.2e-07 32.6 0.7 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DPBB_1 PF03330.18 KDO20989.1 - 0.017 15.4 0.2 0.045 14.0 0.2 1.7 1 0 0 1 1 1 0 Lytic transglycolase TPR_12 PF13424.6 KDO20990.1 - 2e-17 63.2 10.2 2.7e-05 24.4 2.5 5.2 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO20990.1 - 2.4e-11 43.1 7.9 3.7e-05 23.4 0.5 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO20990.1 - 0.00015 21.6 2.0 0.11 12.7 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO20990.1 - 0.0015 18.3 0.0 0.37 10.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO20990.1 - 0.029 14.4 4.1 21 5.4 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat LRR_4 PF12799.7 KDO20991.1 - 0.0021 18.5 2.4 0.081 13.4 0.8 3.9 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO20991.1 - 0.0078 16.2 2.1 4 7.7 0.1 4.2 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 KDO20991.1 - 0.024 15.1 1.6 1.7 9.5 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO20991.1 - 0.083 12.7 2.6 1.1 9.1 1.9 3.2 3 1 0 3 3 3 0 Leucine rich repeat Suf PF05843.14 KDO20992.1 - 2.6e-05 24.4 2.6 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KDO20992.1 - 0.00019 20.7 0.3 0.00045 19.4 0.3 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KDO20992.1 - 0.00029 21.4 1.6 0.0044 17.7 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KDO20992.1 - 0.00076 18.8 0.5 0.0014 17.9 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO20992.1 - 0.033 14.7 0.0 0.25 11.9 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3138 PF11336.8 KDO20992.1 - 9.2 4.7 5.8 13 4.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_C1 PF00112.23 KDO20994.1 - 2.9e-60 204.1 11.6 4.2e-60 203.5 11.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO20994.1 - 0.002 17.0 0.6 0.032 13.0 0.1 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO20995.1 - 8.3e-59 199.3 11.0 8.8e-59 199.2 9.6 1.6 2 0 0 2 2 2 1 Papain family cysteine protease PT PF04886.12 KDO20995.1 - 1.1e-08 34.5 30.6 1.7e-05 24.2 16.8 3.4 2 1 0 2 2 2 2 PT repeat Peptidase_C1_2 PF03051.15 KDO20995.1 - 3.8e-05 22.7 2.5 0.016 14.0 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF4407 PF14362.6 KDO20997.1 - 0.17 11.2 59.1 0.1 11.9 2.6 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4407) YmgB PF10798.8 KDO20997.1 - 0.65 9.8 5.9 0.33 10.8 0.6 3.0 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR NPV_P10 PF05531.12 KDO20997.1 - 1.7 9.1 19.5 3.7 8.1 5.0 5.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Se-cys_synth_N PF12390.8 KDO20997.1 - 1.7 8.9 0.0 1.7 8.9 0.0 3.5 4 0 0 4 4 4 0 Selenocysteine synthase N terminal FlaC_arch PF05377.11 KDO20997.1 - 5.1 7.6 9.8 12 6.3 0.1 5.0 6 1 2 8 8 8 0 Flagella accessory protein C (FlaC) Cortex-I_coil PF09304.10 KDO20997.1 - 6.6 7.0 25.7 4.9 7.4 0.1 5.4 4 1 1 5 5 5 0 Cortexillin I, coiled coil Kinesin PF00225.23 KDO20998.1 - 3.7e-104 348.2 0.3 4.5e-104 348.0 0.3 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO20998.1 - 3.3e-39 134.2 0.0 9.8e-39 132.7 0.0 1.8 2 1 0 2 2 2 1 Microtubule binding SNF2_assoc PF08455.10 KDO20998.1 - 0.0027 16.8 5.8 0.004 16.2 1.1 2.1 2 0 0 2 2 2 2 Bacterial SNF2 helicase associated ResIII PF04851.15 KDO20998.1 - 0.18 11.8 2.4 0.25 11.3 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Nop PF01798.18 KDO20999.1 - 1.7e-88 296.0 0.1 1.7e-88 296.0 0.1 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KDO20999.1 - 1.2e-21 76.9 1.4 1.2e-21 76.9 1.4 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain G0-G1_switch_2 PF15103.6 KDO20999.1 - 1.1 9.7 9.0 2.3 8.7 7.8 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 RNA_polI_A34 PF08208.11 KDO20999.1 - 8.1 6.5 26.1 13 5.8 26.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YfdX PF10938.8 KDO21000.1 - 0.036 14.0 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 YfdX protein Pkinase PF00069.25 KDO21001.1 - 4.3e-43 147.6 0.0 7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KDO21001.1 - 2.4e-41 140.2 0.8 5.5e-18 65.3 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KDO21001.1 - 8.7e-40 136.6 0.0 1.5e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO21001.1 - 4.6e-39 132.3 5.1 2.2e-12 47.2 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21001.1 - 2.7e-32 107.2 3.0 5.5e-07 29.4 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KDO21001.1 - 3.3e-30 103.2 4.6 4.2e-07 30.1 0.0 8.1 9 1 0 9 9 8 5 Ankyrin repeat Ank_5 PF13857.6 KDO21001.1 - 1.2e-29 101.9 6.4 4e-11 42.9 0.0 6.6 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 KDO21001.1 - 0.0015 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO21001.1 - 0.005 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO21001.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO21001.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO21001.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 KDO21002.1 - 1.6e-13 50.3 33.1 2.4e-13 49.7 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO21002.1 - 2.3e-13 49.6 27.8 3.5e-13 49.0 27.8 1.2 1 0 0 1 1 1 1 Amino acid permease CAP PF00188.26 KDO21003.1 - 2.1e-09 38.3 2.8 3.3e-09 37.7 2.8 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family LRR_6 PF13516.6 KDO21006.1 - 2.2e-11 42.9 14.2 0.00095 19.0 0.0 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KDO21006.1 - 3.6e-05 24.1 5.6 0.0057 17.0 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21006.1 - 0.0013 18.5 0.4 0.0013 18.5 0.4 4.2 3 2 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 KDO21006.1 - 0.0062 16.0 1.6 0.057 12.9 0.7 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KDO21006.1 - 0.091 13.4 5.7 4.7 8.1 0.1 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat TAL_effector PF03377.13 KDO21006.1 - 0.26 11.6 4.7 0.61 10.4 0.0 3.1 3 0 0 3 3 3 0 TAL effector repeat Lipase_3 PF01764.25 KDO21007.1 - 5.7e-08 32.7 0.0 1.4e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Vir_act_alpha_C PF10400.9 KDO21007.1 - 0.039 14.6 1.1 0.11 13.2 0.2 2.0 2 0 0 2 2 2 0 Virulence activator alpha C-term Abhydrolase_5 PF12695.7 KDO21007.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KDO21007.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KDO21007.1 - 0.15 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MBOAT PF03062.19 KDO21008.1 - 2.6e-39 135.6 8.7 2.6e-39 135.6 8.7 2.2 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 KDO21009.1 - 4.5e-34 118.3 12.6 4.5e-34 118.3 12.6 1.6 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ELO PF01151.18 KDO21010.1 - 2.4e-63 214.0 16.8 2.8e-63 213.8 16.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.32 KDO21011.1 - 1.3e-27 95.4 9.3 1.3e-05 25.8 0.7 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO21011.1 - 2.9e-18 65.9 0.0 0.00031 21.0 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO21011.1 - 0.00015 21.2 0.0 0.2 11.0 0.1 3.0 3 1 0 3 3 3 2 WD40-like domain VID27 PF08553.10 KDO21011.1 - 0.00024 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Nup160 PF11715.8 KDO21011.1 - 0.0036 16.0 0.5 0.15 10.7 0.2 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KDO21011.1 - 0.0041 15.7 0.0 0.075 11.6 0.0 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain Frtz PF11768.8 KDO21011.1 - 0.22 9.8 0.0 4.5 5.5 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3456 PF11938.8 KDO21012.1 - 3.3e-13 50.4 3.8 6.8e-09 36.4 0.4 2.1 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.17 KDO21012.1 - 0.037 14.1 0.8 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 2 HSP90 PF00183.18 KDO21013.1 - 1.3e-193 644.6 16.8 2e-193 644.0 16.8 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KDO21013.1 - 8e-16 58.5 0.1 1.7e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KDO21013.1 - 1.2e-10 41.3 0.3 4.3e-10 39.6 0.2 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BUD22 PF09073.10 KDO21013.1 - 0.84 8.9 19.9 0.62 9.3 6.7 3.1 3 0 0 3 3 3 0 BUD22 GRDP-like PF07173.12 KDO21014.1 - 8.7e-13 49.1 0.2 1.6e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Jas PF16135.5 KDO21014.1 - 1.3 9.3 5.7 8 6.7 1.7 2.6 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf-C3HC4_3 PF13920.6 KDO21015.1 - 5.8e-11 42.1 10.8 5.8e-11 42.1 10.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO21015.1 - 7.5e-07 28.9 12.1 1.5e-06 28.0 12.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO21015.1 - 3.4e-05 23.7 12.7 3.4e-05 23.7 12.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Tudor-knot PF11717.8 KDO21015.1 - 4.1e-05 23.4 0.4 0.00012 21.9 0.4 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C3HC4 PF00097.25 KDO21015.1 - 7e-05 22.6 9.4 0.00027 20.7 9.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO21015.1 - 0.00062 19.6 13.2 0.0015 18.3 13.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO21015.1 - 0.0015 18.8 12.7 0.0015 18.8 12.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO21015.1 - 0.0021 18.0 13.3 0.0027 17.7 6.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Chromo PF00385.24 KDO21015.1 - 0.0087 16.0 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain KASH_CCD PF14662.6 KDO21015.1 - 0.031 14.1 2.1 0.043 13.6 2.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4113 PF13438.6 KDO21015.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) zf-C3HC4_4 PF15227.6 KDO21015.1 - 0.31 11.2 10.3 0.3 11.3 6.6 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2039 PF10217.9 KDO21015.1 - 7.3 7.0 12.4 13 6.3 12.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_11 PF17123.5 KDO21015.1 - 8.5 6.2 11.8 0.92 9.3 6.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger Maf PF02545.14 KDO21016.1 - 4.6e-40 137.2 0.0 5.1e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein AAA_6 PF12774.7 KDO21017.1 - 3.2e-149 496.3 0.1 3.5e-147 489.6 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO21017.1 - 2.2e-129 432.0 0.8 2.2e-129 432.0 0.8 2.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO21017.1 - 5e-105 350.5 0.0 3.2e-104 347.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KDO21017.1 - 2.9e-100 335.5 0.0 3.4e-98 328.7 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KDO21017.1 - 3.6e-85 284.6 0.5 3.6e-85 284.6 0.5 3.6 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO21017.1 - 4.7e-69 231.5 0.9 5e-65 218.4 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KDO21017.1 - 5.8e-57 192.1 0.0 1.3e-56 190.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KDO21017.1 - 3.6e-49 167.6 15.2 6.8e-49 166.7 15.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KDO21017.1 - 2.2e-44 150.4 0.1 1.6e-39 134.7 0.0 4.0 4 0 0 4 4 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KDO21017.1 - 7.1e-28 97.3 0.0 2.9e-27 95.3 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO21017.1 - 4.2e-16 59.0 1.7 3.1e-15 56.2 0.0 3.2 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 KDO21017.1 - 2.1e-15 56.9 0.1 0.013 15.5 0.0 6.1 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO21017.1 - 8e-09 35.9 0.0 0.12 12.6 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 KDO21017.1 - 2.2e-08 34.6 2.1 0.082 13.3 0.0 4.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO21017.1 - 4.6e-08 33.6 0.0 0.061 13.7 0.0 5.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 KDO21017.1 - 7.6e-06 26.5 1.8 0.023 15.3 0.0 5.3 6 0 0 6 6 4 1 AAA domain AAA_33 PF13671.6 KDO21017.1 - 0.0006 20.0 1.0 6.2 7.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KDO21017.1 - 0.00094 19.5 0.1 8.2 6.9 0.0 4.0 3 0 0 3 3 3 0 RNA helicase ResIII PF04851.15 KDO21017.1 - 0.0012 18.9 0.5 2.2 8.3 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KDO21017.1 - 0.0014 19.1 0.0 1.2 9.6 0.0 4.0 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 KDO21017.1 - 0.0027 16.8 0.1 8.1 5.4 0.0 4.3 4 0 0 4 4 4 0 Type II/IV secretion system protein DUF2075 PF09848.9 KDO21017.1 - 0.013 14.7 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KDO21017.1 - 0.021 14.6 7.2 12 5.6 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_29 PF13555.6 KDO21017.1 - 0.085 12.6 1.1 20 5.0 0.0 3.9 4 0 0 4 4 4 0 P-loop containing region of AAA domain Sec34 PF04136.15 KDO21017.1 - 0.13 12.1 3.7 0.28 11.0 1.2 3.1 2 0 0 2 2 1 0 Sec34-like family Mg_chelatase PF01078.21 KDO21017.1 - 1 8.7 4.2 11 5.3 0.0 3.6 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AA_permease_2 PF13520.6 KDO21018.1 - 9.6e-47 159.8 41.1 1.3e-46 159.4 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO21019.1 - 6.6e-45 153.7 46.4 8.4e-45 153.4 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease HAD_SAK_2 PF18143.1 KDO21020.1 - 0.0098 16.2 0.3 0.013 15.8 0.3 1.3 1 1 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins DLH PF01738.18 KDO21021.1 - 8e-14 51.7 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF4050 PF13259.6 KDO21021.1 - 6.5e-05 23.3 1.4 0.14 12.4 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) Hydrolase_4 PF12146.8 KDO21021.1 - 0.0013 18.0 0.2 0.021 14.1 0.1 2.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 NTP_transf_3 PF12804.7 KDO21021.1 - 0.054 13.8 0.9 0.12 12.8 0.7 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain CBFD_NFYB_HMF PF00808.23 KDO21021.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BAAT_C PF08840.11 KDO21021.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal NHL PF01436.21 KDO21023.1 - 6.1e-17 60.7 10.4 3.7e-06 26.7 0.3 5.1 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 KDO21023.1 - 3.1e-05 23.7 1.2 0.002 17.8 0.1 3.3 1 1 3 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KDO21023.1 - 0.0027 17.7 0.1 55 4.5 0.0 5.0 5 0 0 5 5 5 0 Two component regulator propeller FlgD_ig PF13860.6 KDO21023.1 - 0.055 13.3 0.0 11 6.0 0.0 2.9 2 0 0 2 2 2 0 FlgD Ig-like domain Glyco_hydro_125 PF06824.11 KDO21023.1 - 0.14 11.0 0.1 0.5 9.2 0.0 1.8 2 0 0 2 2 2 0 Metal-independent alpha-mannosidase (GH125) PQQ PF01011.21 KDO21023.1 - 0.64 10.0 6.5 0.3 11.1 0.5 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat SBBP PF06739.11 KDO21023.1 - 1.7 8.7 6.3 1.2 9.2 0.4 3.2 3 0 0 3 3 3 0 Beta-propeller repeat FAP PF07174.11 KDO21023.1 - 3.7 6.9 36.2 7 6.0 36.2 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ParcG PF10274.9 KDO21024.1 - 1.2e-72 243.9 0.1 2.9e-72 242.7 0.1 1.6 1 1 0 1 1 1 1 Parkin co-regulated protein TIG PF01833.24 KDO21025.1 - 5e-52 173.9 34.4 0.00017 21.6 0.0 19.5 20 0 0 20 20 20 15 IPT/TIG domain C2 PF00168.30 KDO21025.1 - 3e-07 30.7 0.0 7.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 KDO21025.1 - 0.0098 15.5 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 1 CEP76 C2 domain Glucodextran_C PF09985.9 KDO21026.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase Metallophos PF00149.28 KDO21027.1 - 4.9e-10 40.3 0.3 9e-10 39.4 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KDO21028.1 - 3.8e-09 37.4 0.0 6.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO21028.1 - 7.6e-05 23.0 0.0 0.00089 19.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Seryl_tRNA_N PF02403.22 KDO21029.1 - 5.3 7.3 22.5 0.87 9.8 1.5 4.1 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Metallophos PF00149.28 KDO21030.1 - 1.1e-12 48.9 0.0 1.6e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO21030.1 - 0.0013 19.0 0.0 0.01 16.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_U57 PF05582.12 KDO21030.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Metallophos PF00149.28 KDO21031.1 - 6.4e-12 46.4 0.0 1e-11 45.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_U57 PF05582.12 KDO21031.1 - 0.06 12.6 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Epimerase_2 PF02350.19 KDO21031.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Metallophos PF00149.28 KDO21032.1 - 7.8e-13 49.4 0.9 1.2e-12 48.8 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI3_PI4_kinase PF00454.27 KDO21033.1 - 4.9e-20 72.4 0.0 8.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase LRR_9 PF14580.6 KDO21034.1 - 4e-18 65.5 0.9 3.7e-16 59.1 0.6 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KDO21034.1 - 3.2e-10 40.1 8.6 0.00074 19.9 0.6 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21034.1 - 0.21 11.4 11.1 0.52 10.1 3.6 2.8 1 1 2 3 3 3 0 Leucine rich repeat adh_short PF00106.25 KDO21035.1 - 2.1e-28 99.1 0.0 7.8e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO21035.1 - 8.4e-18 64.8 0.1 3.1e-17 62.9 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO21035.1 - 3.3e-10 40.2 0.2 5.1e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO21035.1 - 0.00072 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPP_enzyme_C PF02775.21 KDO21035.1 - 0.013 15.3 0.1 0.038 13.8 0.1 1.8 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Eno-Rase_NADH_b PF12242.8 KDO21035.1 - 0.057 13.2 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ubiquitin PF00240.23 KDO21036.1 - 7.8e-12 44.8 0.1 8.9e-12 44.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KDO21036.1 - 0.0031 17.4 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 KDO21036.1 - 0.0061 16.4 0.1 0.0066 16.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KDO21036.1 - 0.022 14.8 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KDO21036.1 - 0.035 14.6 0.0 0.035 14.5 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin-like domain Trypsin PF00089.26 KDO21037.1 - 1.2e-44 152.8 0.5 1.4e-44 152.6 0.5 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 KDO21037.1 - 0.071 12.7 0.0 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 DUF4199 PF13858.6 KDO21038.1 - 0.14 12.5 0.2 0.36 11.2 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Dynein_light PF01221.18 KDO21039.1 - 1.1e-23 83.4 0.4 1.2e-23 83.2 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Herpes_UL21 PF03252.13 KDO21039.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 CBM_15 PF03426.14 KDO21039.1 - 0.19 11.3 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Trypsin PF00089.26 KDO21041.1 - 1.9e-36 126.0 0.1 2.2e-36 125.8 0.1 1.0 1 0 0 1 1 1 1 Trypsin Glyco_transf_20 PF00982.21 KDO21042.1 - 1.8e-90 303.9 0.0 2.5e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KDO21042.1 - 2.7e-42 144.5 0.0 4.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KDO21042.1 - 0.048 13.4 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Orthoreo_P10 PF07204.11 KDO21043.1 - 0.0023 17.8 1.5 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 DHO_dh PF01180.21 KDO21044.1 - 5.2e-105 350.9 0.0 6.2e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KDO21044.1 - 0.15 11.4 0.3 0.26 10.6 0.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase EF-hand_1 PF00036.32 KDO21045.1 - 6.5e-05 22.2 0.1 0.00017 20.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO21045.1 - 0.001 19.5 0.1 0.0035 17.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO21045.1 - 0.0021 17.9 0.0 0.0064 16.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KDO21045.1 - 0.052 13.1 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 EF hand EF-hand_4 PF12763.7 KDO21045.1 - 0.57 10.2 1.9 3.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 KDO21045.1 - 1 9.3 4.7 0.94 9.5 1.3 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif START PF01852.19 KDO21047.1 - 9.6e-06 25.1 0.1 9.6e-06 25.1 0.1 1.7 2 0 0 2 2 2 1 START domain FYVE PF01363.21 KDO21047.1 - 2.8e-05 24.2 15.4 5.8e-05 23.1 15.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO21047.1 - 0.031 14.5 8.8 0.066 13.4 8.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger MatE PF01554.18 KDO21048.1 - 1.5e-45 154.7 28.5 1.1e-26 93.4 9.6 2.6 3 1 0 3 3 3 2 MatE Arrestin_C PF02752.22 KDO21049.1 - 1.7e-14 54.4 0.0 2.1e-12 47.7 0.1 2.6 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KDO21049.1 - 0.00019 21.5 0.0 3.5 7.7 0.0 3.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KDO21049.1 - 0.0017 17.6 0.2 0.81 8.8 0.1 3.2 2 1 1 4 4 4 1 Rgp1 Pox_RNA_pol PF03293.14 KDO21049.1 - 0.18 11.5 0.9 3.7 7.3 0.8 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Asparaginase PF00710.20 KDO21050.1 - 5.4e-58 195.7 0.0 9.2e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KDO21050.1 - 1.2e-26 93.2 0.0 2.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain BRCT_2 PF16589.5 KDO21051.1 - 7.8e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO21051.1 - 0.00021 21.6 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_2 PF08914.11 KDO21051.1 - 0.03 14.5 0.1 0.09 13.0 0.1 1.8 1 0 0 1 1 1 0 Rap1 Myb domain Roughex PF06020.11 KDO21051.1 - 0.049 12.7 11.9 0.091 11.8 11.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein FYVE PF01363.21 KDO21052.1 - 1.8e-08 34.4 7.2 3.9e-08 33.3 7.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO21052.1 - 8.9e-08 31.8 0.1 1.3e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO21052.1 - 0.022 15.0 7.9 0.052 13.8 7.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Pox_F12L PF03337.13 KDO21052.1 - 0.13 10.4 0.0 0.36 8.9 0.1 1.6 2 0 0 2 2 2 0 Poxvirus F12L protein Prok-RING_2 PF14445.6 KDO21052.1 - 2 8.6 8.5 5.8 7.2 8.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 START PF01852.19 KDO21053.1 - 1.2e-11 44.4 0.6 2.6e-11 43.3 0.6 1.5 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO21053.1 - 0.003 17.7 6.5 0.003 17.7 6.5 2.4 3 0 0 3 3 3 1 FYVE zinc finger START PF01852.19 KDO21054.1 - 2.8e-05 23.6 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO21054.1 - 0.00077 19.6 19.1 0.0031 17.6 19.1 2.1 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO21054.1 - 1.3 9.3 7.9 3.2 8.0 7.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC5 PF06221.13 KDO21054.1 - 1.4 8.9 9.8 6.8 6.8 9.6 2.3 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 KDO21054.1 - 3.3 7.8 15.6 1.5 8.9 3.4 3.1 2 1 1 3 3 3 0 Double zinc ribbon IBR PF01485.21 KDO21054.1 - 4.9 7.4 13.4 29 5.0 13.4 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 KDO21054.1 - 6.7 7.0 12.5 1.2e+02 3.0 11.8 2.7 1 1 1 2 2 2 0 AN1-like Zinc finger START PF01852.19 KDO21055.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO21055.1 - 2.3e-06 27.6 14.6 5.3e-06 26.5 14.6 1.7 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO21055.1 - 0.085 13.1 6.8 0.2 11.9 6.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_2 PF13639.6 KDO21055.1 - 2.1 8.8 10.8 7 7.1 10.8 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C2HC5 PF06221.13 KDO21055.1 - 3.6 7.6 10.8 1.7e+02 2.3 10.8 2.6 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FYVE PF01363.21 KDO21056.1 - 1.6e-07 31.4 9.9 3.3e-07 30.3 9.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO21057.1 - 3.4e-10 39.7 0.2 1.2e-09 37.9 0.2 1.9 2 0 0 2 2 2 1 START domain FYVE PF01363.21 KDO21057.1 - 8.7e-08 32.2 15.4 1.8e-07 31.2 15.1 1.8 1 1 0 1 1 1 1 FYVE zinc finger Syntaxin-6_N PF09177.11 KDO21058.1 - 1.5e-20 73.5 4.7 2.5e-19 69.6 0.3 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KDO21058.1 - 2.7e-05 24.0 0.5 7.7e-05 22.6 0.5 1.8 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KDO21058.1 - 0.0032 17.2 4.9 0.0041 16.9 4.9 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF812 PF05667.11 KDO21058.1 - 0.005 15.8 6.9 0.0079 15.1 6.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF1411 PF07199.11 KDO21058.1 - 0.056 13.1 0.9 0.1 12.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Laminin_II PF06009.12 KDO21058.1 - 0.063 13.3 6.8 0.12 12.4 1.3 2.2 2 0 0 2 2 2 0 Laminin Domain II MIS13 PF08202.11 KDO21058.1 - 0.089 12.1 9.5 6.4 6.0 9.5 2.1 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Lebercilin PF15619.6 KDO21058.1 - 0.11 12.2 9.8 0.69 9.5 2.2 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HAUS-augmin3 PF14932.6 KDO21058.1 - 0.13 11.8 3.3 0.41 10.2 0.6 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin PF00804.25 KDO21058.1 - 0.21 11.2 12.8 1.3 8.7 3.3 2.1 2 0 0 2 2 2 0 Syntaxin ATG16 PF08614.11 KDO21058.1 - 0.25 11.6 8.6 0.56 10.4 3.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) XhlA PF10779.9 KDO21058.1 - 0.48 10.7 6.2 0.66 10.2 2.9 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.11 KDO21058.1 - 0.54 9.1 8.2 0.8 8.5 2.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TBCA PF02970.16 KDO21058.1 - 0.63 10.4 4.4 0.3 11.4 1.2 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A ABC_tran_CTD PF16326.5 KDO21058.1 - 2.1 8.7 5.1 24 5.2 0.4 3.4 2 2 0 3 3 3 0 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 KDO21058.1 - 2.6 8.1 7.9 3.2 7.8 1.6 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding KxDL PF10241.9 KDO21058.1 - 2.7 8.3 8.3 2.1 8.7 2.7 3.2 3 2 1 4 4 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 KDO21058.1 - 2.8 7.2 6.9 11 5.3 6.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltransf_25 PF13649.6 KDO21061.1 - 1.7e-09 38.3 0.1 2.8e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO21061.1 - 1.1e-08 35.1 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO21061.1 - 6.6e-08 33.1 0.1 1.3e-07 32.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KDO21061.1 - 3.8e-06 26.2 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 KDO21061.1 - 1.6e-05 24.4 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KDO21061.1 - 0.00012 22.7 0.0 0.00017 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO21061.1 - 0.00024 20.5 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KDO21061.1 - 0.00025 20.7 0.1 0.00032 20.4 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KDO21061.1 - 0.00033 20.6 0.1 0.00041 20.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO21061.1 - 0.00033 20.5 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KDO21061.1 - 0.00034 20.7 0.0 0.00044 20.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO21061.1 - 0.00059 19.3 0.0 0.00069 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KDO21061.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KDO21061.1 - 0.002 17.7 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.10 KDO21061.1 - 0.0063 16.2 0.0 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_9 PF08003.11 KDO21061.1 - 0.072 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) N6_Mtase PF02384.16 KDO21061.1 - 0.081 12.2 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase TrmK PF04816.12 KDO21061.1 - 0.18 11.3 0.1 0.24 10.9 0.1 1.1 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_8 PF05148.15 KDO21061.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase zf-C2H2 PF00096.26 KDO21062.1 - 1.8e-15 56.4 30.8 2.5e-05 24.5 2.9 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO21062.1 - 7.6e-14 51.4 26.2 1.9e-05 24.9 1.7 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO21062.1 - 2.1e-09 37.4 29.4 0.012 16.4 1.6 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KDO21062.1 - 1.9e-05 24.9 15.7 0.23 11.9 0.7 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KDO21062.1 - 0.00061 20.0 12.4 0.036 14.4 0.3 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KDO21062.1 - 0.01 15.9 1.2 0.01 15.9 1.2 4.2 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KDO21062.1 - 0.083 13.0 9.6 0.52 10.4 4.7 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KDO21062.1 - 0.25 11.1 10.3 4.3 7.2 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain CHORD PF04968.12 KDO21062.1 - 3.5 8.4 19.6 1.1 10.0 3.0 3.6 1 1 2 3 3 3 0 CHORD zf-C2HC_2 PF13913.6 KDO21062.1 - 6.9 6.7 12.6 5.9 6.9 0.9 3.7 4 1 0 4 4 4 0 zinc-finger of a C2HC-type PhoLip_ATPase_C PF16212.5 KDO21063.1 - 4.6e-63 213.3 18.0 4.6e-63 213.3 18.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO21063.1 - 3.7e-19 68.2 0.5 1e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KDO21063.1 - 1.5e-10 41.0 0.0 2.8e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO21063.1 - 9e-10 39.2 1.2 6.4e-06 26.6 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO21063.1 - 1.9e-05 24.3 0.0 0.00011 21.8 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO21063.1 - 0.0044 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF900 PF05990.12 KDO21064.1 - 0.076 12.5 0.0 0.098 12.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Anoctamin PF04547.12 KDO21065.1 - 1.1 8.0 9.6 1.7 7.4 0.4 2.8 2 1 1 3 3 3 0 Calcium-activated chloride channel FYVE PF01363.21 KDO21066.1 - 1.6e-15 57.0 32.0 4.6e-09 36.3 10.8 2.4 2 0 0 2 2 2 2 FYVE zinc finger START PF01852.19 KDO21066.1 - 7.2e-10 38.6 1.3 5.7e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 START domain FYVE_2 PF02318.16 KDO21066.1 - 8.4e-10 38.9 16.4 9.6e-05 22.6 4.5 2.4 2 0 0 2 2 2 2 FYVE-type zinc finger IBR PF01485.21 KDO21066.1 - 0.0094 16.2 13.7 0.42 10.9 3.3 2.8 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain DUF3155 PF11352.8 KDO21066.1 - 0.056 13.9 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) zf-RING_2 PF13639.6 KDO21066.1 - 0.062 13.7 33.1 0.14 12.5 12.4 2.7 2 0 0 2 2 2 0 Ring finger domain Siva PF05458.12 KDO21066.1 - 0.28 10.8 21.3 0.2 11.3 4.7 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Benyvirus_14KDa PF07255.11 KDO21066.1 - 0.68 10.2 3.9 9.6 6.5 0.0 3.2 3 0 0 3 3 3 0 Benyvirus 14KDa protein Zn_ribbon_17 PF17120.5 KDO21066.1 - 1.8 8.2 27.1 3.8 7.2 6.5 3.8 3 1 1 4 4 4 0 Zinc-ribbon, C4HC2 type Glutaredoxin PF00462.24 KDO21067.1 - 5.6e-06 26.5 0.0 9.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PT PF04886.12 KDO21067.1 - 0.00017 21.1 51.7 0.0021 17.6 28.4 2.9 2 1 1 3 3 3 2 PT repeat Trypan_PARP PF05887.11 KDO21067.1 - 0.021 14.8 4.2 0.039 13.9 4.1 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AbiEi_3_N PF17194.4 KDO21067.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Mucin PF01456.17 KDO21067.1 - 7.6 6.5 26.6 14 5.7 26.6 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Glutaredoxin PF00462.24 KDO21068.1 - 4.5e-06 26.8 0.0 7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Glyco_hydro_18 PF00704.28 KDO21069.1 - 1.9e-21 77.1 0.6 9.6e-21 74.8 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Esterase PF00756.20 KDO21071.1 - 4e-11 43.0 1.2 3.8e-10 39.8 1.2 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KDO21071.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO21071.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RP-C PF03428.13 KDO21072.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Replication protein C N-terminal domain FYVE_2 PF02318.16 KDO21073.1 - 0.0048 17.1 5.7 0.0077 16.4 5.7 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO21073.1 - 0.26 11.4 14.2 0.54 10.4 14.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 KDO21074.1 - 9.3e-06 25.9 2.0 1.7e-05 25.0 2.0 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO21074.1 - 0.25 11.5 13.1 0.57 10.4 13.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 KDO21074.1 - 1.6 8.7 11.1 3.3 7.6 11.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NOB1_Zn_bind PF08772.11 KDO21075.1 - 1.9e-27 95.2 1.0 3.8e-27 94.2 1.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-CCCH_4 PF18044.1 KDO21075.1 - 1.9e-09 37.1 10.5 2.1e-05 24.2 1.0 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KDO21075.1 - 1.1e-08 34.8 7.9 0.00031 20.6 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KDO21075.1 - 0.00031 21.1 11.5 0.023 15.2 2.3 2.7 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KDO21075.1 - 0.0081 16.2 1.8 0.0081 16.2 1.8 3.4 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KDO21075.1 - 0.026 14.7 2.6 0.85 9.9 2.6 2.4 1 1 0 1 1 1 0 Zinc-finger containing family zf-C3H1 PF10650.9 KDO21075.1 - 0.052 13.3 2.7 0.39 10.5 0.1 2.6 2 0 0 2 2 2 0 Putative zinc-finger domain Torus PF16131.5 KDO21075.1 - 0.21 12.3 6.2 1.1 10.0 0.1 2.8 2 1 1 3 3 3 0 Torus domain SprT-like PF10263.9 KDO21077.1 - 3e-27 94.7 0.0 4.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 SprT-like family FAA_hydrolase_N PF09298.11 KDO21079.1 - 0.029 14.5 0.1 0.033 14.4 0.1 1.1 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Beta-lactamase PF00144.24 KDO21080.1 - 6.1e-43 147.3 1.2 8.6e-43 146.8 1.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO21080.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family DUF676 PF05057.14 KDO21082.1 - 7.8e-32 110.6 0.0 2.7e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KDO21082.1 - 0.00012 22.1 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KDO21082.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KDO21082.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PX PF00787.24 KDO21083.1 - 9.9e-15 54.5 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 PX domain CagA PF03507.13 KDO21084.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 CagA exotoxin Pkinase PF00069.25 KDO21086.1 - 3.8e-18 65.8 0.0 6.8e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21086.1 - 5.2e-06 25.9 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO21086.1 - 9.5e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KDO21087.1 - 1.3e-14 54.2 0.0 1.5e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21087.1 - 2.6e-09 36.8 0.0 2.8e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21087.1 - 0.14 11.5 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Annexin PF00191.20 KDO21090.1 - 6.9e-50 167.0 0.0 1.7e-12 47.2 0.0 4.3 4 0 0 4 4 4 4 Annexin CBM_1 PF00734.18 KDO21091.1 - 3.7e-10 39.6 20.7 7.1e-09 35.5 10.9 2.8 2 1 0 2 2 2 2 Fungal cellulose binding domain CX9C PF16860.5 KDO21091.1 - 1.2 9.2 4.6 1.6 8.8 0.8 3.1 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pkinase PF00069.25 KDO21093.1 - 4.5e-53 180.3 0.0 4.4e-35 121.3 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21093.1 - 7.8e-29 100.7 0.0 6.2e-23 81.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RGS PF00615.19 KDO21093.1 - 8.7e-11 42.1 0.7 1.4e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KDO21093.1 - 1.8e-06 27.5 0.0 0.00038 19.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO21093.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO21093.1 - 0.075 12.7 0.0 3.5 7.2 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CagA PF03507.13 KDO21095.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 CagA exotoxin PX PF00787.24 KDO21096.1 - 9.9e-15 54.5 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF676 PF05057.14 KDO21097.1 - 1.1e-31 110.1 0.0 3.8e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KDO21097.1 - 0.00021 21.2 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KDO21097.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KDO21097.1 - 0.043 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3683 PF12447.8 KDO21101.1 - 0.0013 18.8 0.0 0.0014 18.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) TUDOR PF00567.24 KDO21102.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Tudor domain SprT-like PF10263.9 KDO21103.1 - 3e-27 94.7 0.0 4.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 SprT-like family NOB1_Zn_bind PF08772.11 KDO21105.1 - 2.7e-27 94.7 1.0 5.4e-27 93.8 1.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KDO21105.1 - 3e-27 94.9 0.3 7.6e-27 93.6 0.1 1.8 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-CCCH_4 PF18044.1 KDO21105.1 - 3.4e-09 36.3 10.5 2.7e-05 23.8 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KDO21105.1 - 1.9e-08 34.0 7.9 0.0004 20.2 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KDO21105.1 - 0.00037 20.9 10.9 0.029 14.8 2.3 2.6 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KDO21105.1 - 0.01 15.8 1.8 0.01 15.8 1.8 3.2 3 1 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KDO21105.1 - 0.042 14.1 2.7 1.4 9.2 2.6 2.4 1 1 0 1 1 1 0 Zinc-finger containing family zf-C3H1 PF10650.9 KDO21105.1 - 0.084 12.6 2.7 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 Putative zinc-finger domain Torus PF16131.5 KDO21105.1 - 0.66 10.7 7.6 1.3 9.7 0.1 3.0 3 1 1 4 4 4 0 Torus domain Lyx_isomer PF07385.12 KDO21106.1 - 0.044 13.0 0.2 0.067 12.4 0.2 1.2 1 0 0 1 1 1 0 D-lyxose isomerase LSR PF05624.14 KDO21106.1 - 0.18 11.8 0.8 0.29 11.2 0.8 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) TFIIE-A_C PF11521.8 KDO21106.1 - 2.4 8.5 6.7 3.8 7.9 1.6 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF4094 PF13334.6 KDO21107.1 - 0.034 14.6 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) BIV_Env PF05858.12 KDO21108.1 - 0.19 9.8 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) PrkA PF06798.12 KDO21109.1 - 0.0043 16.7 0.4 0.0065 16.1 0.4 1.2 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain MIS13 PF08202.11 KDO21109.1 - 0.03 13.6 2.6 0.049 12.9 2.6 1.5 1 1 0 1 1 1 0 Mis12-Mtw1 protein family DUF3450 PF11932.8 KDO21109.1 - 0.22 10.8 12.3 0.74 9.1 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Vert_HS_TF PF06546.11 KDO21109.1 - 0.57 9.8 3.7 0.95 9.1 3.7 1.3 1 1 0 1 1 1 0 Vertebrate heat shock transcription factor CHDCT2 PF08074.11 KDO21109.1 - 2.1 8.5 6.3 0.48 10.6 2.4 1.8 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain PVL_ORF50 PF07768.11 KDO21109.1 - 2.2 8.6 5.4 6.8 7.0 0.4 2.5 2 1 0 2 2 2 0 PVL ORF-50-like family FlxA PF14282.6 KDO21109.1 - 9.9 6.2 11.6 4.3 7.4 7.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Band_7 PF01145.25 KDO21110.1 - 3.8e-22 79.1 1.8 1.4e-20 74.1 0.0 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KDO21110.1 - 0.00011 21.9 1.5 0.0055 16.4 0.0 2.4 2 0 0 2 2 2 2 SPFH domain-Band 7 family C_GCAxxG_C_C PF09719.10 KDO21110.1 - 0.02 15.1 0.8 0.039 14.2 0.8 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) DUF1847 PF08901.11 KDO21110.1 - 2.1 8.0 8.0 4.3 7.0 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1847) Band_7 PF01145.25 KDO21111.1 - 8.1e-23 81.3 0.0 8.1e-23 81.3 0.0 2.3 2 1 1 3 3 3 1 SPFH domain / Band 7 family DUF3629 PF12302.8 KDO21111.1 - 0.0042 16.6 2.5 0.0088 15.5 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3629) DUF4058 PF13267.6 KDO21111.1 - 0.015 14.7 1.4 0.015 14.7 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4058) Cortex-I_coil PF09304.10 KDO21112.1 - 0.094 12.9 1.6 0.23 11.7 0.0 2.3 3 0 0 3 3 3 0 Cortexillin I, coiled coil FYVE PF01363.21 KDO21113.1 - 9e-17 61.0 9.5 1.7e-16 60.1 9.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO21113.1 - 4.1e-10 40.4 0.0 8.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO21113.1 - 1.3e-05 25.5 0.0 3.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain DUF3292 PF11696.8 KDO21113.1 - 0.053 11.9 0.2 0.079 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf-4CXXC_R1 PF10497.9 KDO21113.1 - 0.12 12.6 4.3 0.28 11.4 4.3 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CNDH2_M PF16869.5 KDO21113.1 - 1.9 9.2 9.5 0.16 12.6 4.7 1.6 2 0 0 2 2 2 0 PF16858 RAI16-like PF10257.9 KDO21115.1 - 0.011 14.7 0.3 3.8 6.3 0.0 3.3 3 0 0 3 3 3 0 Retinoic acid induced 16-like protein DUF1041 PF06292.17 KDO21115.1 - 0.015 15.7 0.8 16 6.0 0.0 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1041) P16-Arc PF04699.14 KDO21115.1 - 0.032 14.7 0.1 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Asp5 PF17000.5 KDO21115.1 - 0.1 12.7 0.7 25 5.1 0.0 3.9 5 0 0 5 5 5 0 Accessory secretory protein Sec, Asp5 DUF1548 PF07579.11 KDO21115.1 - 0.18 12.2 1.0 0.47 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) Glyco_hydro_6 PF01341.17 KDO21116.1 - 1.5e-48 166.1 1.6 3.1e-48 165.1 1.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 DUF4448 PF14610.6 KDO21116.1 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1206 PF06724.11 KDO21116.1 - 0.1 12.7 1.4 1.7 8.8 0.7 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) SOG2 PF10428.9 KDO21116.1 - 3.3 6.8 9.4 4.6 6.3 9.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM154 PF15102.6 KDO21116.1 - 9.8 6.1 7.4 97 2.8 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family Glyco_hydro_6 PF01341.17 KDO21118.1 - 1.7e-35 123.2 1.3 3.7e-35 122.1 1.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 RTX PF02382.15 KDO21119.1 - 0.098 12.3 0.2 0.098 12.3 0.2 1.0 1 0 0 1 1 1 0 N-terminal domain in RTX protein Phage_TAC_14 PF16462.5 KDO21119.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 Phage tail assembly chaperone protein, TAC p25-alpha PF05517.12 KDO21124.1 - 0.021 15.0 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 p25-alpha Trp_repressor PF01371.19 KDO21124.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Trp repressor protein PRMT5_TIM PF17285.2 KDO21124.1 - 0.17 11.0 0.2 0.27 10.4 0.2 1.3 1 0 0 1 1 1 0 PRMT5 TIM barrel domain DUF2373 PF10180.9 KDO21127.1 - 4.1e-18 65.0 0.2 7e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF4874 PF16173.5 KDO21127.1 - 0.073 12.7 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) CAP PF00188.26 KDO21129.1 - 8.2e-17 62.2 4.3 1.3e-16 61.5 4.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M8 PF01457.16 KDO21129.1 - 0.029 13.1 1.0 0.039 12.6 1.0 1.2 1 0 0 1 1 1 0 Leishmanolysin YchF-GTPase_C PF06071.13 KDO21130.1 - 2e-39 133.6 0.3 5.5e-39 132.2 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KDO21130.1 - 1.7e-19 69.9 0.0 3.7e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO21130.1 - 1.3e-06 28.0 0.0 3.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KDO21130.1 - 0.0044 17.0 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.6 KDO21130.1 - 0.058 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO21130.1 - 0.15 12.5 0.0 0.77 10.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF4524 PF15025.6 KDO21131.1 - 4.4e-08 33.0 0.0 7.6e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4520 PF15016.6 KDO21131.1 - 8.9e-07 28.9 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) RGI1 PF10843.8 KDO21132.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Respiratory growth induced protein 1 ATP-synt_C PF00137.21 KDO21133.1 - 3.8e-28 97.6 32.6 1.1e-14 54.5 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CH_2 PF06294.11 KDO21134.1 - 2e-16 59.9 0.0 4.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 KDO21134.1 - 9e-10 38.8 0.0 2.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase Spore_II_R PF09551.10 KDO21134.1 - 2.1 8.8 4.1 7.1 7.1 4.1 2.0 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) GTP_EFTU PF00009.27 KDO21135.1 - 2.7e-53 180.4 0.9 3.3e-53 180.1 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KDO21135.1 - 1.7e-09 37.9 3.8 4e-09 36.8 3.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO21135.1 - 1.1e-07 31.9 0.2 2.4e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO21135.1 - 0.0017 17.9 0.1 0.018 14.6 0.1 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KDO21135.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KDO21135.1 - 0.0027 17.6 0.1 0.5 10.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase EFG_II PF14492.6 KDO21135.1 - 0.0034 17.4 0.1 0.0073 16.4 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 KDO21135.1 - 0.0059 15.9 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 KDO21135.1 - 0.034 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KDO21135.1 - 0.04 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO21135.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family ChaC PF04752.12 KDO21136.1 - 2.5e-50 171.0 0.0 2.8e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 KDO21136.1 - 0.00036 21.1 0.0 0.00052 20.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KDO21136.1 - 0.00084 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DSPc PF00782.20 KDO21136.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CAP PF00188.26 KDO21137.1 - 0.0017 19.2 2.3 0.0031 18.3 2.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TFIIA PF03153.13 KDO21138.1 - 7.9 6.3 10.1 9.9 6.0 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAIM1 PF06905.13 KDO21139.1 - 0.062 13.0 0.1 0.084 12.6 0.1 1.1 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Peptidase_C69 PF03577.15 KDO21141.1 - 9.2e-40 136.8 0.0 4.5e-35 121.4 0.0 2.5 2 1 0 2 2 2 2 Peptidase family C69 Peptidase_C69 PF03577.15 KDO21142.1 - 2.9e-41 141.7 0.0 2.8e-40 138.5 0.0 2.3 1 1 0 1 1 1 1 Peptidase family C69 Bac_surface_Ag PF01103.23 KDO21143.1 - 8.5e-36 124.1 0.0 1e-35 123.8 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KDO21143.1 - 0.01 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 Surface antigen variable number repeat ShlB PF03865.13 KDO21143.1 - 0.064 12.7 0.1 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_1 PF08478.10 KDO21143.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 POTRA domain, FtsQ-type TRAM_LAG1_CLN8 PF03798.16 KDO21144.1 - 1.8e-31 109.4 22.6 2.7e-31 108.9 22.6 1.3 1 0 0 1 1 1 1 TLC domain Ank_2 PF12796.7 KDO21146.1 - 1.5e-90 297.9 22.7 3.7e-15 56.3 0.0 9.5 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21146.1 - 1.7e-81 267.6 28.7 1.7e-12 47.6 0.0 12.4 5 3 8 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.30 KDO21146.1 - 4.1e-69 226.2 33.6 1.1e-06 28.7 0.0 15.7 14 1 1 15 15 15 11 Ankyrin repeat Ank_3 PF13606.6 KDO21146.1 - 4.3e-69 220.2 15.2 4.3e-05 23.6 0.0 16.4 17 0 0 17 17 17 13 Ankyrin repeat Ank_5 PF13857.6 KDO21146.1 - 1.5e-68 226.0 22.4 1.5e-10 41.1 0.0 13.1 4 1 9 14 14 14 13 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO21146.1 - 2.2e-30 105.8 0.0 3.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21146.1 - 2.9e-29 102.3 0.0 5.5e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MukF_C PF17193.4 KDO21146.1 - 0.029 14.5 0.1 32 4.6 0.0 4.1 3 2 2 5 5 5 0 MukF C-terminal domain DUF2112 PF09885.9 KDO21146.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Kinase-like PF14531.6 KDO21146.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TRAM_LAG1_CLN8 PF03798.16 KDO21148.1 - 5.2e-34 117.7 15.7 7.5e-34 117.2 15.7 1.2 1 0 0 1 1 1 1 TLC domain Glu_dehyd_C PF16912.5 KDO21149.1 - 0.019 14.5 0.1 0.019 14.5 0.1 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus PAGK PF15284.6 KDO21149.1 - 0.43 10.5 7.9 0.28 11.1 0.3 3.6 3 0 0 3 3 3 0 Phage-encoded virulence factor OB_NTP_bind PF07717.16 KDO21150.1 - 1.3e-21 76.7 0.1 3e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KDO21150.1 - 1.7e-21 76.5 1.4 1.8e-20 73.3 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KDO21150.1 - 4.7e-13 49.5 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO21150.1 - 1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO21150.1 - 3.3e-05 24.2 0.1 0.00017 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KDO21150.1 - 3.8e-05 22.9 0.0 8.2e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KDO21150.1 - 0.00026 20.8 0.1 0.00074 19.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KDO21150.1 - 0.00057 20.2 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KDO21150.1 - 0.019 14.5 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 KDO21150.1 - 0.02 14.5 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KDO21150.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.7 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KDO21150.1 - 1.1 9.7 4.7 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 KDO21150.1 - 3.5 8.1 0.0 3.5 8.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain ECH_1 PF00378.20 KDO21151.1 - 3.5e-37 128.1 0.4 4.7e-37 127.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO21151.1 - 1.2e-15 57.8 0.4 1.8e-15 57.3 0.4 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 KDO21152.1 - 4.7e-65 219.6 0.0 5.6e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21152.1 - 3.4e-29 101.9 0.0 4.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO21152.1 - 0.0017 17.4 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO21152.1 - 0.0072 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO21152.1 - 0.045 13.7 2.0 0.31 10.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family PX PF00787.24 KDO21153.1 - 7.9e-10 38.7 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 PX domain HECT PF00632.25 KDO21154.1 - 5e-50 170.7 0.0 9.4e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 KDO21154.1 - 0.00057 20.4 0.5 0.35 11.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Acetyltransf_6 PF13480.7 KDO21154.1 - 0.26 11.4 1.9 0.66 10.1 0.5 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-RING_5 PF14634.6 KDO21155.1 - 0.00023 21.1 16.0 0.00036 20.4 16.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KDO21155.1 - 0.0021 18.4 13.8 0.0025 18.1 13.0 1.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO21155.1 - 0.0045 16.8 15.4 0.014 15.3 15.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO21155.1 - 0.013 15.4 14.1 0.013 15.4 14.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO21155.1 - 0.023 14.7 7.7 0.061 13.4 7.8 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KDO21155.1 - 0.061 13.2 6.6 0.12 12.3 6.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 KDO21155.1 - 0.14 12.1 14.4 0.27 11.1 14.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO21155.1 - 2 8.3 13.2 3.4 7.6 13.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MYND PF01753.18 KDO21156.1 - 0.0012 18.9 9.4 0.0019 18.2 9.4 1.4 1 0 0 1 1 1 1 MYND finger PDZ_6 PF17820.1 KDO21156.1 - 0.0012 18.7 0.0 0.03 14.2 0.0 2.7 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 KDO21156.1 - 0.0066 16.8 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KDO21157.1 - 1.3e-05 24.9 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 PDZ domain IQ PF00612.27 KDO21159.1 - 1.8e-21 73.9 75.8 0.0088 15.8 1.3 13.8 13 0 0 13 13 13 12 IQ calmodulin-binding motif BolA PF01722.18 KDO21159.1 - 0.0048 17.1 0.5 0.089 13.1 0.0 3.0 3 0 0 3 3 3 1 BolA-like protein Exo_endo_phos PF03372.23 KDO21160.1 - 5.1e-15 55.6 0.1 1.5e-14 54.1 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 KDO21160.1 - 6.6e-11 42.3 1.0 1.4e-10 41.3 1.0 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Exo_endo_phos_2 PF14529.6 KDO21160.1 - 0.011 15.6 0.2 0.039 13.8 0.2 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase zf-MYND PF01753.18 KDO21160.1 - 0.12 12.4 1.2 0.35 11.0 1.2 1.9 1 0 0 1 1 1 0 MYND finger Ion_trans PF00520.31 KDO21161.1 - 6.5e-28 97.6 16.7 9.9e-28 97.0 16.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO21161.1 - 2.9e-11 43.2 5.8 8.4e-11 41.7 5.8 1.9 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 KDO21161.1 - 9.1e-11 41.7 0.0 2.8e-10 40.1 0.1 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain ADH_N PF08240.12 KDO21161.1 - 1.8e-08 34.2 0.0 5e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.25 KDO21162.1 - 1e-58 198.8 0.0 1.4e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21162.1 - 5.4e-37 127.5 0.0 7.8e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO21162.1 - 9.2e-06 24.7 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO21162.1 - 0.022 14.1 0.0 0.065 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KDO21162.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KDO21162.1 - 0.095 12.0 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SGS PF05002.15 KDO21163.1 - 8.9e-30 102.6 5.0 1.6e-29 101.9 5.0 1.4 1 0 0 1 1 1 1 SGS domain TPR_1 PF00515.28 KDO21163.1 - 2.5e-10 39.7 12.9 0.00021 21.0 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO21163.1 - 4.2e-07 29.6 21.3 0.0025 17.8 0.6 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO21163.1 - 1.3e-06 27.9 9.7 8.5e-06 25.4 6.1 3.0 2 1 1 3 3 3 2 TPR repeat CS PF04969.16 KDO21163.1 - 2e-06 28.7 0.1 4.2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 KDO21163.1 - 0.00061 20.4 19.6 0.0026 18.4 12.3 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO21163.1 - 0.00093 19.2 6.0 8.7 6.8 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO21163.1 - 0.017 15.4 2.4 0.35 11.3 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3211 PF11485.8 KDO21163.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) TPR_19 PF14559.6 KDO21163.1 - 0.25 11.9 15.6 0.24 11.9 8.4 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO21163.1 - 0.33 11.1 7.7 0.55 10.4 5.8 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO21163.1 - 1.1 10.3 20.6 0.79 10.7 3.6 4.4 3 1 3 6 6 4 0 Tetratricopeptide repeat Histone PF00125.24 KDO21164.1 - 1e-39 135.9 0.7 1.1e-39 135.8 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO21164.1 - 0.00077 19.5 0.1 0.00099 19.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KDO21164.1 - 0.0022 18.1 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO21164.1 - 0.0042 17.4 0.2 0.0059 17.0 0.2 1.2 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO21164.1 - 0.0067 16.6 0.7 0.0095 16.1 0.7 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO21164.1 - 0.031 14.6 0.2 0.043 14.1 0.2 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_5 PF13857.6 KDO21165.1 - 8.4e-11 41.9 0.2 2.8e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO21165.1 - 2.5e-07 31.1 0.2 1.7e-05 25.2 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO21165.1 - 4.3e-07 30.1 0.1 0.0028 18.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO21165.1 - 6.7e-06 26.6 0.0 6.1e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO21165.1 - 5.8e-05 23.2 0.1 0.0028 18.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ion_trans PF00520.31 KDO21166.1 - 7.7e-15 54.8 16.8 1.1e-14 54.3 16.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO21166.1 - 5.1e-12 45.7 0.1 1e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Baculo_PEP_C PF04513.12 KDO21167.1 - 0.038 14.0 0.3 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 KDO21167.1 - 0.059 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) CYTH PF01928.21 KDO21167.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 CYTH domain cNMP_binding PF00027.29 KDO21168.1 - 1.1e-13 51.1 0.0 2.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO21168.1 - 5.5e-11 42.2 9.2 8.4e-11 41.6 9.2 1.3 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.25 KDO21169.1 - 3.4e-68 229.9 0.0 4.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21169.1 - 5.5e-31 107.8 0.0 7.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO21169.1 - 3.5e-06 26.5 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO21169.1 - 6.7e-05 22.9 0.0 0.22 11.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO21169.1 - 0.0006 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO21169.1 - 0.0032 17.1 0.3 0.031 13.9 0.1 2.1 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KDO21169.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KDO21169.1 - 0.039 13.5 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Act-Frag_cataly PF09192.10 KDO21169.1 - 0.091 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic YrbL-PhoP_reg PF10707.9 KDO21169.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_5 PF07728.14 KDO21170.1 - 1.5e-11 44.4 0.0 2.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DHC_N1 PF08385.12 KDO21171.1 - 4.2e-27 95.0 0.0 4.6e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DSHCT PF08148.12 KDO21171.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain SNARE_assoc PF09335.11 KDO21173.1 - 3.5e-14 53.3 8.2 3.5e-14 53.3 8.2 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein MM_CoA_mutase PF01642.22 KDO21174.1 - 3.9e-235 781.2 0.1 4.7e-235 781.0 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KDO21174.1 - 1.2e-14 54.4 0.0 2.8e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain SNARE_assoc PF09335.11 KDO21175.1 - 3.8e-18 66.1 7.1 3.8e-18 66.1 7.1 2.3 3 1 0 3 3 3 1 SNARE associated Golgi protein DENN PF02141.21 KDO21176.1 - 1.4e-30 106.6 5.0 1.3e-29 103.5 5.0 2.1 1 1 0 1 1 1 1 DENN (AEX-3) domain FliT PF05400.13 KDO21178.1 - 6.3 7.7 6.7 0.81 10.5 2.6 1.6 2 0 0 2 2 2 0 Flagellar protein FliT RloB PF13707.6 KDO21179.1 - 0.022 15.0 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 RloB-like protein NAD_binding_10 PF13460.6 KDO21181.1 - 7.9e-19 68.3 0.0 9.4e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KDO21181.1 - 2.7e-13 49.6 0.6 2.7e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KDO21181.1 - 1.7e-09 37.6 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KDO21181.1 - 4e-08 33.0 0.0 8.9e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KDO21181.1 - 0.0015 17.7 0.0 0.016 14.3 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KDO21181.1 - 0.0046 16.4 0.0 0.0067 15.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KDO21181.1 - 0.11 11.9 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF1308 PF07000.11 KDO21181.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) HIM1 PF08732.10 KDO21181.1 - 0.25 10.9 0.0 0.4 10.2 0.0 1.4 1 1 0 1 1 1 0 HIM1 PSD3 PF07626.11 KDO21182.1 - 0.05 14.1 0.1 0.07 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) Ras PF00071.22 KDO21184.1 - 1e-47 161.8 0.7 1.2e-47 161.5 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO21184.1 - 6.8e-31 107.0 0.4 1.4e-30 106.0 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO21184.1 - 1e-09 38.1 0.2 4.5e-09 36.0 0.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO21184.1 - 1.6e-07 31.4 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO21184.1 - 0.0002 20.8 0.1 0.00033 20.1 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KDO21184.1 - 0.00092 19.5 0.0 0.0029 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KDO21184.1 - 0.00098 19.1 0.0 0.0024 17.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KDO21184.1 - 0.0014 19.0 0.1 0.0025 18.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KDO21184.1 - 0.0044 16.6 0.3 1.5 8.3 0.0 2.9 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KDO21184.1 - 0.011 15.5 0.4 0.066 13.0 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KDO21184.1 - 0.013 15.0 0.2 0.03 13.8 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 KDO21184.1 - 0.014 14.8 0.1 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KDO21184.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KDO21184.1 - 0.027 14.2 0.1 0.061 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KDO21184.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KDO21184.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 KDO21184.1 - 0.086 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO21184.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 KDO21184.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_M20 PF01546.28 KDO21185.1 - 1.4e-21 77.2 0.3 1.9e-21 76.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO21185.1 - 4.3e-08 33.1 0.1 8.4e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain AAA PF00004.29 KDO21186.1 - 5.3e-43 146.6 0.0 8.5e-33 113.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KDO21186.1 - 1.1e-08 35.2 0.0 2.6e-05 24.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO21186.1 - 3.6e-08 34.0 3.4 0.023 15.1 0.0 3.7 3 1 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KDO21186.1 - 4.9e-06 26.9 0.1 0.053 13.8 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KDO21186.1 - 6.9e-06 25.8 0.1 1.7e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 KDO21186.1 - 7.3e-05 23.3 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KDO21186.1 - 0.00012 22.1 0.0 0.75 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KDO21186.1 - 0.00028 20.7 0.1 0.094 12.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KDO21186.1 - 0.00043 20.5 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KDO21186.1 - 0.0012 18.3 0.1 0.0095 15.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KDO21186.1 - 0.0014 18.5 0.2 0.035 14.0 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KDO21186.1 - 0.0015 18.3 0.0 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO21186.1 - 0.0018 18.1 0.0 0.045 13.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KDO21186.1 - 0.0019 18.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KDO21186.1 - 0.003 16.8 0.0 0.0089 15.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 KDO21186.1 - 0.0049 16.5 0.7 0.18 11.3 0.4 2.8 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 KDO21186.1 - 0.0058 16.6 0.3 0.57 10.1 0.0 3.3 4 0 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.12 KDO21186.1 - 0.0077 15.5 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 KDO21186.1 - 0.0084 15.6 0.0 2.2 7.8 0.1 2.8 3 1 0 3 3 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO21186.1 - 0.0099 16.3 0.0 0.39 11.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KDO21186.1 - 0.01 15.9 0.0 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 KDO21186.1 - 0.025 14.3 0.2 0.59 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KDO21186.1 - 0.029 13.6 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.6 KDO21186.1 - 0.034 14.6 0.0 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO21186.1 - 0.05 13.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KDO21186.1 - 0.061 13.1 0.0 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KDO21186.1 - 0.064 12.9 0.0 4.8 6.9 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KDO21186.1 - 0.1 12.5 0.0 18 5.2 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 KDO21186.1 - 0.18 11.3 0.1 16 5.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KDO21186.1 - 0.19 12.1 1.8 7.9 6.8 0.3 3.0 3 1 1 4 4 3 0 AAA domain PhoH PF02562.16 KDO21186.1 - 0.26 10.7 1.0 0.66 9.4 0.4 1.9 3 0 0 3 3 2 0 PhoH-like protein Adeno_IVa2 PF02456.15 KDO21186.1 - 0.28 9.9 0.1 3.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Ndc1_Nup PF09531.10 KDO21187.1 - 3.6e-06 26.0 10.3 6.1e-06 25.2 0.4 2.4 2 1 0 2 2 2 2 Nucleoporin protein Ndc1-Nup MJ1316 PF04457.12 KDO21189.1 - 7.9e-25 87.4 0.8 1.3e-24 86.7 0.8 1.4 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain AKAP7_NLS PF10469.9 KDO21189.1 - 6.1e-24 85.1 0.0 1.6e-23 83.7 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KDO21189.1 - 0.00057 19.8 0.0 0.0015 18.5 0.0 1.7 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily RNA_ligase PF09414.10 KDO21190.1 - 7.3e-26 91.4 0.0 1e-25 90.9 0.0 1.2 1 0 0 1 1 1 1 RNA ligase MJ1316 PF04457.12 KDO21191.1 - 3.3e-24 85.4 1.3 6e-24 84.6 1.3 1.5 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain AKAP7_NLS PF10469.9 KDO21191.1 - 1.2e-20 74.3 0.0 2.3e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain NTP_transf_2 PF01909.23 KDO21191.1 - 0.2 12.0 0.0 0.61 10.4 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Tetraspanin PF00335.20 KDO21192.1 - 1.1e-08 35.1 7.8 1.8e-08 34.4 7.8 1.2 1 0 0 1 1 1 1 Tetraspanin family zf-CHC2 PF01807.20 KDO21192.1 - 0.1 12.4 0.5 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger PIRT PF15099.6 KDO21192.1 - 0.24 11.0 1.3 0.59 9.7 1.3 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family UCH PF00443.29 KDO21193.1 - 1.4e-35 123.0 0.0 2.3e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KDO21193.1 - 7.1e-14 51.9 0.8 1.5e-13 50.8 0.8 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KDO21193.1 - 0.003 17.2 0.0 0.049 13.2 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDE_1 PF03184.19 KDO21194.1 - 2.7e-07 30.4 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KDO21194.1 - 1.4e-06 28.2 0.1 3.1e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KDO21194.1 - 1.3e-05 24.7 1.3 2.6e-05 23.7 1.3 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.6 KDO21194.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 KDO21194.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KDO21194.1 - 0.27 11.4 2.5 0.46 10.7 0.6 2.3 2 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase p450 PF00067.22 KDO21197.1 - 3.6e-46 157.9 0.0 3e-35 121.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MORN PF02493.20 KDO21199.1 - 1.5e-50 166.2 52.5 5.3e-06 26.0 3.3 12.3 12 0 0 12 12 12 12 MORN repeat DJ-1_PfpI PF01965.24 KDO21200.1 - 1e-21 77.5 0.0 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KDO21200.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 1 1 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain HABP4_PAI-RBP1 PF04774.15 KDO21201.1 - 4.9e-14 53.2 15.2 4.6e-13 50.0 15.2 2.2 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family MatE PF01554.18 KDO21202.1 - 3.1e-35 121.2 25.0 6.5e-18 64.9 10.5 3.0 3 0 0 3 3 3 2 MatE MatE PF01554.18 KDO21203.1 - 2.1e-38 131.5 42.9 4.2e-22 78.5 17.5 2.5 2 0 0 2 2 2 2 MatE Neurensin PF14927.6 KDO21203.1 - 0.031 14.0 2.5 0.071 12.8 1.0 2.3 2 0 0 2 2 2 0 Neurensin MatE PF01554.18 KDO21204.1 - 1.5e-39 135.3 39.9 6.4e-23 81.2 14.0 2.5 3 0 0 3 3 3 2 MatE MatE PF01554.18 KDO21205.1 - 1.1e-37 129.2 36.8 7e-22 77.8 13.4 2.5 2 0 0 2 2 2 2 MatE DUF4271 PF14093.6 KDO21205.1 - 3.4 7.5 17.6 0.029 14.3 3.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) Oxidored-like PF09791.9 KDO21206.1 - 4.5e-08 32.6 6.9 6.9e-08 32.0 6.9 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal MatE PF01554.18 KDO21207.1 - 4.1e-37 127.3 39.1 2.5e-21 76.0 14.3 2.5 2 0 0 2 2 2 2 MatE Anoctamin PF04547.12 KDO21209.1 - 1.5e-15 57.1 1.8 2.8e-15 56.1 1.8 1.4 1 1 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO21209.1 - 0.036 13.8 0.0 4.1 7.1 0.1 2.2 1 1 1 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin C2 PF00168.30 KDO21210.1 - 1.9e-15 57.0 0.0 3.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Anoctamin PF04547.12 KDO21210.1 - 0.005 15.7 0.0 0.0064 15.4 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PhoLip_ATPase_C PF16212.5 KDO21211.1 - 3.8e-70 236.5 25.3 3.8e-70 236.5 25.3 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KDO21211.1 - 4.3e-12 45.9 0.0 7.9e-11 41.9 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO21211.1 - 2.2e-07 31.4 5.6 0.00082 19.7 1.8 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO21211.1 - 6.2e-06 25.9 0.0 6.2e-06 25.9 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO21211.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UxuA PF03786.13 KDO21211.1 - 0.14 10.9 0.1 0.96 8.2 0.0 2.0 1 1 1 2 2 2 0 D-mannonate dehydratase (UxuA) DUF1826 PF08856.11 KDO21211.1 - 0.15 12.0 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) PhoLip_ATPase_C PF16212.5 KDO21212.1 - 5.5e-65 219.6 24.5 5.5e-65 219.6 24.5 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO21212.1 - 4.5e-21 74.3 4.4 4.5e-21 74.3 4.4 2.8 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KDO21212.1 - 5.3e-12 45.7 0.0 1.3e-10 41.2 0.0 2.9 3 1 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO21212.1 - 6.2e-09 36.4 2.9 7.6e-05 23.1 0.6 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO21212.1 - 1.9e-07 30.8 3.5 4.9e-07 29.4 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO21212.1 - 0.0022 17.8 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_6 PF13516.6 KDO21213.1 - 5.1e-41 135.2 41.4 4.2e-05 23.3 0.2 14.4 14 0 0 14 14 14 10 Leucine Rich repeat LRR_4 PF12799.7 KDO21213.1 - 5.4e-13 48.9 24.1 0.024 15.1 0.0 9.0 5 4 6 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21213.1 - 6.3e-07 29.1 29.2 0.0035 17.1 2.7 9.9 5 4 5 10 10 10 5 Leucine rich repeat LRR_1 PF00560.33 KDO21213.1 - 2.7e-06 27.1 13.4 7.9 7.5 0.0 11.0 13 0 0 13 13 13 1 Leucine Rich Repeat LRR_12 PF18837.1 KDO21213.1 - 0.14 11.8 1.2 14 5.5 0.0 3.9 3 0 0 3 3 3 0 Leucine-rich repeat DUF3597 PF12200.8 KDO21214.1 - 0.17 12.4 0.6 0.21 12.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) zf-dskA_traR PF01258.17 KDO21216.1 - 0.00058 19.7 1.7 0.00095 19.1 1.7 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger zf-LYAR PF08790.11 KDO21216.1 - 0.11 12.4 1.9 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KDO21216.1 - 0.24 11.5 2.2 0.52 10.5 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) UPF0020 PF01170.18 KDO21217.1 - 1.6e-10 41.0 0.3 1.7e-08 34.4 0.3 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KDO21217.1 - 0.00024 20.9 0.0 0.0014 18.4 0.0 2.0 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 KDO21217.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 N-6 DNA Methylase N6-adenineMlase PF10237.9 KDO21217.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase MethyltransfD12 PF02086.15 KDO21217.1 - 0.23 11.1 0.3 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase ADH_zinc_N PF00107.26 KDO21219.1 - 5.6e-23 81.3 0.6 2.8e-22 79.1 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO21219.1 - 5.1e-16 59.9 0.0 1.3e-15 58.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO21219.1 - 5.6e-13 48.7 0.2 2.3e-11 43.6 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.21 KDO21219.1 - 0.32 11.1 1.6 0.98 9.5 0.3 2.1 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Spc7 PF08317.11 KDO21220.1 - 0.0021 17.0 19.1 0.0021 17.0 19.1 8.5 4 3 4 9 9 9 5 Spc7 kinetochore protein TRAF_BIRC3_bd PF16673.5 KDO21220.1 - 2.5 8.0 8.0 5.5 6.9 0.0 4.8 3 1 1 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Filament PF00038.21 KDO21220.1 - 2.6 7.5 115.3 0.51 9.9 23.8 9.9 2 2 5 8 8 8 0 Intermediate filament protein Prok-TraM PF09228.10 KDO21221.1 - 0.14 12.5 1.0 0.59 10.5 1.0 2.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Pkinase PF00069.25 KDO21222.1 - 2.4e-80 269.7 0.0 2.8e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21222.1 - 9.4e-39 133.2 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21222.1 - 9.1e-08 31.7 0.0 4.8e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO21222.1 - 1.3e-05 24.8 0.3 2.2e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO21222.1 - 7.9e-05 22.7 0.1 0.12 12.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KDO21222.1 - 0.00042 20.0 0.1 0.16 11.6 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO21222.1 - 0.0014 17.7 0.2 0.0021 17.1 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO21222.1 - 0.0045 16.4 1.0 0.0095 15.3 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO21222.1 - 0.006 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Enolase_C PF00113.22 KDO21223.1 - 2.2e-40 138.8 0.0 5.7e-40 137.4 0.0 1.6 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KDO21223.1 - 1e-17 64.5 0.0 1.9e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Dpy-30 PF05186.13 KDO21223.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Dpy-30 motif NMD3 PF04981.13 KDO21224.1 - 1.9e-68 230.6 6.0 1.9e-68 230.6 6.0 1.8 2 0 0 2 2 2 1 NMD3 family zf-LYAR PF08790.11 KDO21224.1 - 0.068 13.1 1.4 1.9 8.4 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger PRCC PF10253.9 KDO21225.1 - 3.9e-10 40.9 5.3 1e-09 39.5 5.3 1.6 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting INCENP_ARK-bind PF03941.15 KDO21225.1 - 1.6 8.8 6.4 1 9.4 1.2 2.6 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region PBP1_TM PF14812.6 KDO21225.1 - 7.9 6.9 10.4 9.1 6.7 1.2 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mg_trans_NIPA PF05653.14 KDO21227.1 - 3.3e-35 121.6 15.8 4.8e-35 121.1 15.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Fz PF01392.22 KDO21227.1 - 9.2e-05 23.0 2.0 0.00018 22.1 2.0 1.5 1 1 0 1 1 1 1 Fz domain EamA PF00892.20 KDO21227.1 - 0.00049 20.3 5.7 0.00049 20.3 5.7 3.3 2 1 1 3 3 3 2 EamA-like transporter family TMEM234 PF10639.9 KDO21227.1 - 0.1 12.7 8.5 0.2 11.7 1.1 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 Autophagy_act_C PF03987.15 KDO21227.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain EmrE PF13536.6 KDO21227.1 - 0.32 10.5 9.6 0.022 14.4 2.1 2.3 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter DUF4131 PF13567.6 KDO21227.1 - 1.1 8.9 7.2 0.41 10.3 0.4 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Peptidase_U4 PF03419.13 KDO21227.1 - 3.2 7.0 18.0 1.5 8.0 4.8 2.3 1 1 1 2 2 2 0 Sporulation factor SpoIIGA PIP5K PF01504.18 KDO21228.1 - 3.5e-66 223.2 0.0 5.6e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 KDO21228.1 - 0.00085 18.7 5.9 0.0015 17.9 5.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) EF-hand_6 PF13405.6 KDO21229.1 - 1.1e-08 34.3 0.2 0.18 11.8 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KDO21229.1 - 1.9e-07 30.1 0.0 0.2 11.3 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KDO21229.1 - 6.8e-07 29.6 0.1 0.7 10.4 0.0 4.5 3 1 2 5 5 5 3 EF-hand domain pair DUF1086 PF06461.11 KDO21229.1 - 0.17 11.7 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) EF-hand_8 PF13833.6 KDO21229.1 - 0.29 11.0 1.9 25 4.8 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair Brix PF04427.18 KDO21230.1 - 6.6e-33 114.5 0.0 8.6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain Mpp10 PF04006.12 KDO21231.1 - 4.3e-143 478.0 61.7 5.3e-143 477.7 61.7 1.1 1 0 0 1 1 1 1 Mpp10 protein Adenylsucc_synt PF00709.21 KDO21231.1 - 2.9 6.7 6.1 2.9 6.7 0.3 2.3 1 1 0 2 2 2 0 Adenylosuccinate synthetase EF-hand_1 PF00036.32 KDO21232.1 - 3.2e-06 26.3 2.0 0.82 9.4 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 KDO21232.1 - 7.4e-06 25.2 7.9 0.49 10.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO21232.1 - 0.00032 20.4 1.2 5.4 7.2 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KDO21232.1 - 0.022 15.2 1.1 5.7 7.5 0.8 3.0 2 1 0 2 2 2 0 EF-hand domain pair VCBS PF13517.6 KDO21232.1 - 0.023 15.3 9.5 4.1 8.1 0.2 3.7 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 KDO21232.1 - 0.26 11.5 7.7 1.6 9.0 3.1 3.1 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_8 PF13833.6 KDO21232.1 - 1.5 8.8 4.0 86 3.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair HA PF03457.14 KDO21233.1 - 3.9e-22 78.3 0.1 6.4e-08 32.8 0.0 3.4 3 0 0 3 3 3 3 Helicase associated domain Band_7 PF01145.25 KDO21234.1 - 3.5e-19 69.5 11.1 7.1e-18 65.2 11.1 2.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DivIVA PF05103.13 KDO21234.1 - 0.00095 19.3 4.9 0.0017 18.5 4.9 1.4 1 0 0 1 1 1 1 DivIVA protein V-ATPase_G_2 PF16999.5 KDO21234.1 - 0.0058 17.0 4.1 0.012 16.0 4.1 1.6 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KDO21234.1 - 0.028 14.5 4.6 0.028 14.5 4.6 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Glyco_hydro_31 PF01055.26 KDO21235.1 - 4e-89 299.8 6.8 5e-89 299.5 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 KDO21235.1 - 4.9e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Trefoil PF00088.18 KDO21235.1 - 1.7e-06 27.8 4.2 3.5e-06 26.8 4.2 1.6 1 0 0 1 1 1 1 Trefoil (P-type) domain Metallopep PF12044.8 KDO21236.1 - 1.3e-56 192.1 0.1 2e-56 191.4 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KDO21236.1 - 6.3e-12 45.6 0.0 5.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Jacalin-like lectin domain Peptidase_M66 PF10462.9 KDO21236.1 - 0.0046 15.9 0.7 0.0073 15.3 0.7 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 KDO21236.1 - 0.031 14.1 0.5 0.069 13.0 0.5 1.6 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KDO21236.1 - 0.093 13.3 1.6 0.27 11.8 1.6 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KDO21236.1 - 0.13 12.4 1.1 0.25 11.4 1.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Nup84_Nup100 PF04121.13 KDO21237.1 - 2.6e-111 373.0 0.5 8e-111 371.4 0.5 1.8 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 AMP-binding PF00501.28 KDO21238.1 - 5.7e-23 81.2 4.7 1.2e-22 80.1 4.7 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO21238.1 - 0.14 13.1 0.9 0.35 11.9 0.9 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain UAA PF08449.11 KDO21238.1 - 1.1 8.4 3.6 1 8.5 0.8 1.9 1 1 1 2 2 2 0 UAA transporter family DHC_N2 PF08393.13 KDO21239.1 - 1.1e-46 159.7 0.0 2.1e-46 158.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 KDO21239.1 - 5.2e-12 46.0 0.0 3.2e-11 43.4 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 KDO21239.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KDO21239.1 - 6.8e-05 22.1 0.0 0.00015 20.9 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO21239.1 - 0.00018 21.1 0.0 0.00077 19.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_6 PF12774.7 KDO21239.1 - 0.00031 19.8 0.0 0.00061 18.8 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 KDO21239.1 - 0.026 14.3 0.0 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KDO21239.1 - 0.049 13.9 3.1 52 4.0 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KDO21239.1 - 0.08 13.0 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO21239.1 - 0.1 11.8 0.0 1.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 KDO21239.1 - 0.21 11.7 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Helicase_C_3 PF13625.6 KDO21239.1 - 0.23 11.6 5.9 4.9 7.3 0.1 4.2 3 1 1 4 4 4 0 Helicase conserved C-terminal domain MMR_HSR1_Xtn PF16897.5 KDO21240.1 - 1e-38 131.6 0.0 2.2e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KDO21240.1 - 8.2e-20 71.0 0.1 3e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KDO21240.1 - 1e-15 57.5 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KDO21240.1 - 8.3e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO21240.1 - 0.00063 19.8 0.7 0.21 11.7 0.0 2.8 2 1 1 3 3 3 2 Dynamin family AAA_28 PF13521.6 KDO21240.1 - 0.016 15.5 0.1 0.045 14.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KDO21240.1 - 0.033 14.4 0.7 0.24 11.6 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO21240.1 - 0.035 13.6 0.3 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 KDO21240.1 - 0.046 14.1 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TUG-UBL1 PF11470.8 KDO21241.1 - 5.5e-19 68.1 1.4 2.9e-18 65.8 0.0 2.8 4 0 0 4 4 4 1 TUG ubiquitin-like domain PUB PF09409.10 KDO21241.1 - 1.2e-07 31.5 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 PUB domain RBD PF02196.15 KDO21241.1 - 0.002 18.1 0.2 0.0061 16.6 0.1 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain GST_N_3 PF13417.6 KDO21242.1 - 1.4e-17 63.8 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO21242.1 - 5.6e-17 61.8 0.0 9.7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO21242.1 - 5e-13 49.1 0.0 8.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO21242.1 - 4.8e-07 29.9 0.0 8.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO21242.1 - 0.00022 21.4 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO21242.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FHA PF00498.26 KDO21243.1 - 2.6e-24 85.3 0.5 1.1e-11 45.0 0.1 2.3 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 KDO21243.1 - 5.5e-19 68.3 0.0 5.3e-11 42.7 0.0 3.3 2 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain ALG11_N PF15924.5 KDO21244.1 - 4e-76 255.7 0.8 5.4e-76 255.3 0.8 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KDO21244.1 - 2.5e-24 85.7 0.0 3.9e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO21244.1 - 9.5e-14 52.0 0.2 2e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO21244.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 E1-E2_ATPase PF00122.20 KDO21245.1 - 7.5e-50 169.0 1.9 7.5e-50 169.0 1.9 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KDO21245.1 - 5e-38 130.6 8.3 5.1e-18 65.4 1.6 3.8 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KDO21245.1 - 4.1e-22 78.1 0.0 1e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO21245.1 - 6e-18 65.9 0.1 5.8e-08 33.3 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO21245.1 - 6.1e-13 48.2 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO21245.1 - 5.6e-05 23.0 3.8 0.0028 17.4 0.3 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 KDO21245.1 - 0.28 11.5 6.6 4.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) MORN PF02493.20 KDO21247.1 - 1.8e-51 169.0 127.8 1.4e-06 27.8 1.0 19.0 21 0 0 21 21 21 14 MORN repeat ABC_tran PF00005.27 KDO21248.1 - 1.8e-33 116.0 0.0 2.1e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KDO21248.1 - 0.00014 21.4 0.0 0.052 13.0 0.0 2.0 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KDO21248.1 - 0.0015 17.5 0.9 0.0043 15.9 0.1 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 KDO21248.1 - 0.0015 19.0 0.2 0.0023 18.4 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KDO21248.1 - 0.0016 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KDO21248.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO21248.1 - 0.002 18.0 0.1 0.21 11.4 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO21248.1 - 0.0022 17.8 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KDO21248.1 - 0.0051 16.6 0.8 0.016 14.9 0.8 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO21248.1 - 0.015 15.6 0.3 0.094 13.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KDO21248.1 - 0.039 14.2 0.6 0.9 9.8 0.6 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KDO21248.1 - 0.098 11.8 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KDO21248.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KDO21248.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Exog_C PF18026.1 KDO21251.1 - 0.034 14.2 0.7 0.21 11.7 0.7 2.5 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain PKcGMP_CC PF16808.5 KDO21251.1 - 0.041 13.7 0.1 0.041 13.7 0.1 7.7 6 1 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SAC3 PF12209.8 KDO21251.1 - 0.23 11.6 3.9 12 6.2 0.4 3.5 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain DCP2 PF05026.13 KDO21251.1 - 0.27 11.6 2.0 0.57 10.6 0.1 2.6 2 0 0 2 2 2 0 Dcp2, box A domain DUF3010 PF11215.8 KDO21251.1 - 0.42 10.9 5.5 0.73 10.1 1.5 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3010) MLD PF11647.8 KDO21251.1 - 4 7.8 7.6 3.4 8.0 0.7 3.7 3 0 0 3 3 3 0 Membrane Localization Domain DUF382 PF04037.13 KDO21252.1 - 4.6e-52 175.5 0.0 4.6e-52 175.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KDO21252.1 - 3.6e-18 65.1 2.1 6.9e-18 64.3 2.1 1.5 1 0 0 1 1 1 1 PSP PGA2 PF07543.12 KDO21252.1 - 0.55 10.2 0.0 0.55 10.2 0.0 4.1 4 0 0 4 4 4 0 Protein trafficking PGA2 NAGLU PF05089.12 KDO21253.1 - 1.3e-112 376.0 3.3 7.8e-112 373.5 3.3 1.9 1 1 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KDO21253.1 - 5.6e-64 216.2 0.6 8.1e-64 215.7 0.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KDO21253.1 - 3.1e-13 49.3 0.0 8.4e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain SlyX PF04102.12 KDO21253.1 - 0.13 12.9 0.1 0.29 11.8 0.1 1.6 1 0 0 1 1 1 0 SlyX Metallophos PF00149.28 KDO21256.1 - 3.7e-35 122.3 0.9 5.1e-35 121.8 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KDO21256.1 - 0.0055 16.4 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KDO21256.1 - 0.043 14.3 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain ABC_tran PF00005.27 KDO21257.1 - 5e-54 182.5 0.0 7.1e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO21257.1 - 1.1e-53 182.6 23.3 1.4e-30 106.6 9.5 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO21257.1 - 3.9e-21 76.1 1.7 2.7e-07 30.7 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO21257.1 - 8.7e-06 26.4 0.7 0.0013 19.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO21257.1 - 3.3e-05 23.4 0.0 0.27 10.6 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 KDO21257.1 - 0.0001 21.8 11.6 0.0001 21.8 11.6 3.7 4 0 0 4 4 3 2 ABC-2 type transporter AAA_15 PF13175.6 KDO21257.1 - 0.00013 21.8 0.0 0.35 10.5 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO21257.1 - 0.0014 18.6 0.1 0.41 10.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KDO21257.1 - 0.0022 17.7 0.6 0.055 13.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain Insulin_TMD PF17870.1 KDO21257.1 - 0.013 15.6 0.5 0.068 13.3 0.0 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment AAA_22 PF13401.6 KDO21257.1 - 0.026 14.8 0.1 6.1 7.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KDO21257.1 - 0.029 14.6 0.0 5.6 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KDO21257.1 - 0.029 14.1 4.8 0.48 10.2 0.1 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain BRX_assoc PF16627.5 KDO21257.1 - 0.057 13.6 0.1 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain AAA_16 PF13191.6 KDO21257.1 - 0.13 12.7 0.2 24 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 KDO21257.1 - 0.33 10.7 1.6 10 5.8 0.2 2.6 3 0 0 3 3 3 0 MukB N-terminal SRP54 PF00448.22 KDO21257.1 - 0.37 10.4 3.1 3.5 7.2 0.5 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PEX11 PF05648.14 KDO21258.1 - 5.2e-12 45.7 0.7 5.2e-12 45.7 0.7 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) CSTF2_hinge PF14327.6 KDO21259.1 - 1.6e-11 44.4 3.6 2.5e-11 43.8 0.2 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KDO21259.1 - 2.1e-09 36.8 8.0 4.8e-09 35.6 8.0 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal YdaT_toxin PF06254.11 KDO21259.1 - 0.013 16.1 0.1 0.022 15.3 0.1 1.4 1 0 0 1 1 1 0 Putative bacterial toxin ydaT TMP-TENI PF02581.17 KDO21259.1 - 0.21 10.9 1.3 0.24 10.7 0.2 1.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase Phage_TAC_7 PF10109.9 KDO21259.1 - 0.23 11.6 1.4 0.35 11.0 0.7 1.7 2 1 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 CCDC85 PF10226.9 KDO21260.1 - 0.03 14.0 0.1 0.039 13.6 0.1 1.3 1 1 0 1 1 1 0 CCDC85 family DUF1515 PF07439.11 KDO21260.1 - 0.06 13.4 0.1 0.063 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3586 PF12131.8 KDO21262.1 - 6.2 7.1 10.6 3.1 8.1 1.7 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3586) Adeno_E1B_55K PF01696.17 KDO21263.1 - 4.1 6.0 8.6 6.4 5.4 8.6 1.3 1 1 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen DapB_N PF01113.20 KDO21264.1 - 0.22 11.6 1.7 5.1 7.2 0.1 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus CxC6 PF18721.1 KDO21264.1 - 5.1 7.4 27.6 2.1 8.7 1.3 3.9 1 1 3 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases PyrI_C PF02748.15 KDO21268.1 - 0.013 15.4 0.6 0.026 14.4 0.6 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4431 PF14485.6 KDO21268.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) WW PF00397.26 KDO21269.1 - 0.0016 18.5 0.1 0.004 17.2 0.1 1.7 1 0 0 1 1 1 1 WW domain Atx10homo_assoc PF09759.9 KDO21269.1 - 0.0026 17.7 2.7 0.013 15.5 0.1 3.3 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KDO21269.1 - 0.011 15.8 14.0 0.099 12.7 1.1 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Gp58 PF07902.11 KDO21269.1 - 0.095 11.0 0.4 0.18 10.0 0.4 1.4 1 0 0 1 1 1 0 gp58-like protein zf-TAZ PF02135.16 KDO21270.1 - 8.1e-13 48.6 16.1 8.1e-13 48.6 16.1 1.8 2 0 0 2 2 2 1 TAZ zinc finger Cupin_4 PF08007.12 KDO21271.1 - 5.9e-18 65.4 0.0 9.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein CENP-B_dimeris PF09026.10 KDO21271.1 - 0.0027 18.0 12.2 0.0053 17.1 12.2 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 KDO21271.1 - 0.013 15.8 3.7 0.016 15.5 3.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFB6 PF17110.5 KDO21271.1 - 0.016 15.0 1.5 0.032 14.0 1.5 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Cupin_2 PF07883.11 KDO21271.1 - 0.023 14.4 0.1 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 Cupin domain RXT2_N PF08595.11 KDO21271.1 - 0.024 14.7 2.0 0.039 14.0 2.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KDO21271.1 - 0.04 13.2 11.5 0.058 12.7 11.5 1.2 1 0 0 1 1 1 0 NOA36 protein Cupin_8 PF13621.6 KDO21271.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin-like domain ACP PF06857.11 KDO21271.1 - 0.095 12.9 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Sigma70_ner PF04546.13 KDO21271.1 - 0.12 12.2 4.3 0.21 11.5 4.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cupin_1 PF00190.22 KDO21271.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Cupin BUD22 PF09073.10 KDO21271.1 - 0.27 10.5 1.4 0.42 9.9 1.4 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KDO21271.1 - 0.46 9.9 4.9 0.61 9.5 4.9 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 KDO21271.1 - 0.49 10.1 16.2 0.71 9.6 16.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KDO21271.1 - 1.8 6.7 7.5 2.8 6.1 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KDO21271.1 - 3 6.9 19.8 4.4 6.3 19.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KDO21271.1 - 3.2 5.9 5.5 4.3 5.5 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 KDO21272.1 - 1e-19 70.9 9.4 2.5e-12 47.2 0.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO21272.1 - 8.1e-14 51.6 0.0 5.4e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KDO21272.1 - 1.7e-11 43.3 1.6 0.012 16.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO21272.1 - 3.4e-11 43.2 3.7 1.2e-08 35.0 0.5 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO21272.1 - 1.6e-10 40.7 0.0 1.1e-09 37.9 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO21272.1 - 1.6e-10 41.3 3.5 0.00017 22.1 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO21272.1 - 6.2e-10 39.1 4.8 0.025 15.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 KDO21273.1 - 3.2e-30 105.4 0.0 7.2e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21273.1 - 3.7e-28 98.5 0.0 5.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KDO21273.1 - 1.8e-18 66.9 0.0 5.2e-13 49.4 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO21273.1 - 5.7e-16 57.0 0.1 0.00016 21.8 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KDO21273.1 - 1.8e-15 56.6 0.9 6.9e-06 26.3 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KDO21273.1 - 4.8e-13 49.1 0.1 1.6e-08 34.6 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO21273.1 - 3.2e-12 46.7 0.0 2.4e-06 28.0 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Kinase-like PF14531.6 KDO21273.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KDO21273.1 - 0.13 11.6 0.0 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.18 KDO21273.1 - 0.28 10.0 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Pkinase PF00069.25 KDO21274.1 - 1.7e-32 112.8 0.0 5e-32 111.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KDO21274.1 - 3.2e-26 91.7 0.1 2e-13 50.7 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KDO21274.1 - 2.5e-23 82.7 0.0 5.1e-23 81.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO21274.1 - 4.8e-17 62.1 0.1 2.9e-08 34.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21274.1 - 2.1e-15 56.6 0.0 1.9e-11 43.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21274.1 - 1.5e-12 46.5 0.0 0.00011 22.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO21274.1 - 7.8e-12 45.1 0.7 4.5e-05 23.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Kinase-like PF14531.6 KDO21274.1 - 0.00048 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO21274.1 - 0.00097 19.1 0.1 0.39 10.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family PHD PF00628.29 KDO21275.1 - 1.1e-06 28.4 7.7 1.8e-06 27.7 7.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KDO21275.1 - 0.0058 16.5 4.1 0.013 15.4 4.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 KDO21275.1 - 0.029 14.6 6.1 0.06 13.7 6.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 KDO21275.1 - 0.032 14.2 4.4 0.032 14.2 4.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KDO21275.1 - 1.3 9.5 10.0 2.4 8.6 10.0 1.5 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 KDO21275.1 - 1.4 9.0 5.8 3.3 7.8 5.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon RICTOR_V PF14668.6 KDO21276.1 - 0.085 13.1 0.1 1 9.6 0.0 2.5 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 KDO21276.1 - 0.33 11.1 12.1 2.6 8.2 0.2 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KDO21276.1 - 0.62 10.5 7.4 6.9 7.2 0.3 4.3 4 0 0 4 4 4 0 HEAT repeat PP2C PF00481.21 KDO21277.1 - 2.3e-19 70.0 0.4 1.9e-10 40.8 0.0 3.0 2 2 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KDO21277.1 - 2.5e-06 27.3 0.5 2.8e-05 23.9 0.4 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Rib_5-P_isom_A PF06026.14 KDO21278.1 - 4.5e-64 215.2 0.0 5.6e-64 214.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KDO21278.1 - 0.00039 20.4 0.1 0.0023 17.9 0.0 2.0 1 1 1 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 KDO21278.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DsrD PF08679.11 KDO21278.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Pkinase PF00069.25 KDO21279.1 - 3.5e-31 108.5 0.0 4.6e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21279.1 - 4.6e-26 91.7 0.0 5.4e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21279.1 - 0.027 13.8 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KDO21280.1 - 8.3e-41 140.1 0.0 1.2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21280.1 - 2.1e-38 132.1 0.0 3.3e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO21280.1 - 6.3e-16 58.5 0.0 2.8e-05 24.6 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21280.1 - 3.7e-10 39.2 0.0 0.081 13.5 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO21280.1 - 4.1e-10 39.7 0.4 6.8e-06 26.3 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO21280.1 - 6e-10 39.6 0.0 4.7e-07 30.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO21280.1 - 9.8e-06 25.8 0.3 0.27 11.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Kinase-like PF14531.6 KDO21280.1 - 0.0001 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 KDO21280.1 - 0.0034 16.3 0.3 0.016 14.1 0.1 1.9 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Peptidase_M27 PF01742.17 KDO21280.1 - 0.051 12.7 0.0 3 6.9 0.0 2.1 1 1 1 2 2 2 0 Clostridial neurotoxin zinc protease PIP49_C PF12260.8 KDO21280.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 KDO21280.1 - 0.1 12.5 0.0 0.86 9.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 KDO21281.1 - 1.1e-30 106.0 13.1 6.2e-14 52.3 0.5 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO21281.1 - 4.5e-27 95.1 0.0 1e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21281.1 - 3.7e-26 91.9 0.0 6.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KDO21281.1 - 7.6e-22 75.0 5.2 1.2e-06 28.4 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KDO21281.1 - 1.6e-21 75.7 8.6 1e-07 32.0 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KDO21281.1 - 3.9e-18 65.6 2.2 3.4e-08 33.9 0.1 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21281.1 - 6.8e-18 64.5 5.9 1.2e-09 38.2 0.3 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PAH PF02671.21 KDO21281.1 - 0.0072 16.4 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 2 Paired amphipathic helix repeat Haspin_kinase PF12330.8 KDO21281.1 - 0.037 13.0 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FCD PF07729.12 KDO21281.1 - 0.1 13.0 0.5 0.29 11.6 0.5 1.7 1 0 0 1 1 1 0 FCD domain BT1 PF03092.16 KDO21282.1 - 4.5e-16 58.2 15.0 6.7e-16 57.6 4.2 2.6 2 1 0 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO21282.1 - 8.9e-06 24.9 44.9 9.7e-06 24.7 32.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4474 PF14751.6 KDO21282.1 - 0.034 13.6 0.1 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) YrvL PF14184.6 KDO21282.1 - 8.5 6.5 11.3 0.1 12.7 0.4 3.3 3 0 0 3 3 3 0 Regulatory protein YrvL Lipase_GDSL_2 PF13472.6 KDO21283.1 - 5.1e-25 88.9 0.1 6.2e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO21283.1 - 1.1e-14 54.9 0.0 1.9e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF459 PF04311.13 KDO21283.1 - 0.074 12.0 0.0 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF459) Tctex-1 PF03645.13 KDO21284.1 - 2.2e-20 72.8 0.0 2.5e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family GTP_EFTU PF00009.27 KDO21285.1 - 6e-34 117.3 2.7 9.6e-32 110.1 2.7 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KDO21285.1 - 1.1e-21 76.9 0.1 2.7e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KDO21285.1 - 2.1e-09 37.4 0.0 5.1e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KDO21285.1 - 1.7e-07 30.9 1.5 4.6e-07 29.5 0.1 2.6 3 0 0 3 3 3 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KDO21285.1 - 5.4e-06 26.4 1.5 0.0009 19.2 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KDO21285.1 - 4.8e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KDO21285.1 - 0.0086 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KDO21285.1 - 0.012 15.4 0.1 0.097 12.4 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KDO21285.1 - 0.013 15.1 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Ras family MeaB PF03308.16 KDO21285.1 - 0.014 14.4 0.9 0.038 13.0 0.7 1.8 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 KDO21285.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KDO21285.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU_D4 PF14578.6 KDO21285.1 - 0.053 13.4 0.7 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 UreE_N PF02814.15 KDO21285.1 - 0.059 13.0 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 1 0 UreE urease accessory protein, N-terminal domain Polysacc_deac_1 PF01522.21 KDO21285.1 - 0.077 12.9 0.2 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide deacetylase AAA_23 PF13476.6 KDO21285.1 - 0.71 10.3 5.3 1.2 9.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain 7tm_7 PF08395.12 KDO21286.1 - 0.17 11.0 3.1 0.73 9.0 1.0 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor GnHR_trans PF12369.8 KDO21289.1 - 0.014 16.1 0.5 2.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region Cys_box PF17869.1 KDO21289.1 - 0.078 13.1 3.6 6.5 7.0 0.2 2.2 2 0 0 2 2 2 0 Anosmin cysteine rich domain NINJA_B PF16136.5 KDO21290.1 - 0.0034 17.7 0.1 0.0048 17.2 0.1 1.2 1 0 0 1 1 1 1 Putative nuclear localisation signal WD40 PF00400.32 KDO21300.1 - 9.7e-13 48.4 28.2 0.0023 18.7 0.2 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat WD40_like PF17005.5 KDO21300.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 KDO21300.1 - 6.1 7.5 15.4 22 5.7 0.0 6.4 8 0 0 8 8 8 0 PQQ-like domain UCH PF00443.29 KDO21302.1 - 2e-39 135.7 0.0 2.8e-38 131.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO21302.1 - 6.6e-10 39.1 0.0 1.9e-08 34.3 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Calreticulin PF00262.18 KDO21304.1 - 3.6e-87 292.6 14.0 1.5e-60 205.1 6.2 2.3 1 1 1 2 2 2 2 Calreticulin family HCMV_UL139 PF12507.8 KDO21304.1 - 0.16 12.4 3.0 0.098 13.0 1.2 1.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Hydrolase PF00702.26 KDO21305.1 - 4.9e-16 59.6 0.0 6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KDO21305.1 - 7.6e-14 52.2 0.0 1.1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO21305.1 - 4.6e-06 26.6 0.2 1.2e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like ADK PF00406.22 KDO21306.1 - 1e-162 535.3 0.0 2.2e-45 154.5 0.0 4.3 4 0 0 4 4 4 4 Adenylate kinase AAA_17 PF13207.6 KDO21306.1 - 9.1e-84 278.7 0.0 1e-21 77.8 0.0 5.1 5 0 0 5 5 5 4 AAA domain DUF4821 PF16092.5 KDO21306.1 - 2.3e-55 188.1 0.1 5.2e-50 170.5 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) AAA_18 PF13238.6 KDO21306.1 - 1.5e-21 77.3 0.0 0.00039 21.0 0.0 4.8 4 0 0 4 4 4 4 AAA domain AAA_33 PF13671.6 KDO21306.1 - 5.1e-18 65.6 0.0 0.0061 16.7 0.0 6.3 4 1 0 4 4 4 4 AAA domain Hydin_ADK PF17213.3 KDO21306.1 - 6.7e-16 59.2 14.5 0.44 10.8 0.1 8.4 6 2 2 8 8 8 5 Hydin Adenylate kinase-like domain ADK_lid PF05191.14 KDO21306.1 - 3.9e-09 36.3 0.1 0.086 12.8 0.0 4.2 3 0 0 3 3 3 3 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 KDO21306.1 - 4.6e-08 33.1 3.0 0.25 11.1 0.0 4.2 4 0 0 4 4 4 3 Cytidylate kinase Thymidylate_kin PF02223.17 KDO21306.1 - 7.2e-06 25.8 0.1 2.2 8.0 0.0 6.4 6 2 0 7 7 7 1 Thymidylate kinase Pyr_redox_2 PF07992.14 KDO21306.1 - 8.1e-06 25.3 0.0 5.5e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.6 KDO21306.1 - 2.7e-05 24.5 0.2 0.53 10.6 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 KDO21306.1 - 8.8e-05 22.8 1.1 0.34 11.2 0.0 4.4 5 0 0 5 5 4 1 AAA domain Rad17 PF03215.15 KDO21306.1 - 0.00011 22.2 5.3 2.4 8.0 0.0 4.2 4 0 0 4 4 4 2 Rad17 P-loop domain MAF_flag10 PF01973.18 KDO21306.1 - 0.00066 19.4 1.8 10 5.8 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function DUF115 AAA PF00004.29 KDO21306.1 - 0.0036 17.7 3.6 4.1 7.8 0.0 4.9 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) CoA_trans PF01144.23 KDO21306.1 - 0.029 13.7 0.0 0.68 9.3 0.0 2.7 3 0 0 3 3 3 0 Coenzyme A transferase Limkain-b1 PF11608.8 KDO21306.1 - 0.067 13.3 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 RNA_helicase PF00910.22 KDO21306.1 - 0.072 13.5 1.1 1.1 9.7 0.0 3.4 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.6 KDO21306.1 - 0.11 12.1 0.1 0.88 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KDO21306.1 - 0.18 11.5 1.2 1.1 9.0 0.0 2.8 4 0 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 KDO21306.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 KDO21306.1 - 0.82 9.1 3.5 36 3.7 0.1 3.7 4 0 0 4 4 4 0 Chromatin associated protein KTI12 Arm PF00514.23 KDO21306.1 - 2.1 8.5 4.5 0.9 9.7 0.0 2.9 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat Peptidase_C69 PF03577.15 KDO21307.1 - 8.8e-38 130.3 0.6 5.4e-34 117.8 0.1 2.4 2 1 0 2 2 2 2 Peptidase family C69 Phage_attach PF05354.11 KDO21307.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Phage Head-Tail Attachment FAD_binding_2 PF00890.24 KDO21309.1 - 9.4e-122 407.1 4.2 1.3e-121 406.6 4.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KDO21309.1 - 1.1e-44 151.5 1.6 1.7e-44 150.9 1.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KDO21309.1 - 0.00015 21.1 0.9 0.029 13.6 0.2 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KDO21309.1 - 0.00047 19.5 0.3 0.0014 17.9 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO21309.1 - 0.0088 15.2 7.1 0.03 13.4 4.2 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KDO21309.1 - 0.013 14.2 0.5 0.039 12.7 0.4 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KDO21309.1 - 0.022 14.0 0.3 0.045 13.0 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KDO21309.1 - 0.034 13.7 1.3 0.06 12.9 0.4 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO21309.1 - 0.089 11.8 0.6 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AadA_C PF18280.1 KDO21310.1 - 0.038 14.1 1.3 0.14 12.3 0.1 2.5 3 0 0 3 3 3 0 Aminoglycoside adenyltransferase C-terminal domain GMC_oxred_N PF00732.19 KDO21311.1 - 1.6e-28 100.0 0.0 7.4e-28 97.8 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KDO21311.1 - 4.2e-09 36.4 2.8 1.1e-07 31.8 2.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO21311.1 - 8e-09 35.6 0.3 4.3e-08 33.3 0.1 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_C PF05199.13 KDO21311.1 - 8.6e-08 32.8 0.1 1.7e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KDO21311.1 - 2.1e-07 30.5 0.0 2.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KDO21311.1 - 2.1e-06 27.1 0.8 0.00054 19.1 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KDO21311.1 - 2.8e-06 26.8 0.2 5e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KDO21311.1 - 3.4e-05 23.1 0.8 0.00049 19.3 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KDO21311.1 - 4.8e-05 22.2 0.2 0.00063 18.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KDO21311.1 - 0.0014 17.9 0.3 0.0026 17.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KDO21311.1 - 0.0071 15.7 0.8 0.034 13.5 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KDO21311.1 - 0.0091 14.9 0.2 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KDO21311.1 - 0.015 15.9 0.1 0.91 10.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO21311.1 - 0.024 13.9 0.0 0.33 10.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO21311.1 - 0.039 13.0 0.2 0.21 10.7 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A EF-hand_1 PF00036.32 KDO21312.1 - 4.6e-11 41.4 0.7 0.0001 21.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO21312.1 - 4.4e-10 38.7 0.5 0.00022 20.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO21312.1 - 3e-08 32.8 0.7 2.2e-05 23.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO21312.1 - 1.3e-07 31.9 0.1 0.014 15.8 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO21312.1 - 0.00013 21.8 1.9 0.78 9.6 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair PRP38_assoc PF12871.7 KDO21312.1 - 0.099 13.3 8.2 0.22 12.1 8.2 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term WW PF00397.26 KDO21313.1 - 2.4e-08 33.9 0.9 6.5e-08 32.5 0.9 1.8 1 0 0 1 1 1 1 WW domain APG6_N PF17675.1 KDO21313.1 - 0.00067 20.2 4.3 0.00067 20.2 4.3 8.7 3 1 3 7 7 7 3 Apg6 coiled-coil region SOGA PF11365.8 KDO21313.1 - 0.084 14.0 0.0 0.084 14.0 0.0 8.6 4 2 5 10 10 10 0 Protein SOGA Nitroreductase PF00881.24 KDO21314.1 - 9.1e-28 97.4 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family WD40 PF00400.32 KDO21315.1 - 0.00047 20.9 0.1 0.11 13.4 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO21315.1 - 0.0008 19.7 0.0 1.9 8.8 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KDO21317.1 - 6.5e-10 38.9 0.5 1.7e-09 37.6 0.5 1.8 1 0 0 1 1 1 1 WW domain PH PF00169.29 KDO21317.1 - 7e-07 29.7 0.1 2.9e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 PH domain CCDC154 PF15450.6 KDO21317.1 - 0.0036 15.9 1.1 0.005 15.4 1.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 ZapB PF06005.12 KDO21317.1 - 0.037 14.5 1.9 1.9 9.0 1.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 KDO21317.1 - 0.072 13.3 0.2 0.63 10.3 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper PH_11 PF15413.6 KDO21317.1 - 0.091 13.2 0.0 0.23 11.9 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain BRE1 PF08647.11 KDO21317.1 - 0.13 12.4 5.8 0.045 13.8 1.7 2.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF1977 PF09320.11 KDO21317.1 - 0.15 12.3 3.0 0.54 10.5 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) DUF16 PF01519.16 KDO21317.1 - 0.18 12.3 1.7 13 6.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 KDO21317.1 - 2.1 8.6 7.3 0.73 10.1 3.6 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4509 PF14970.6 KDO21318.1 - 0.0002 21.3 0.1 0.0016 18.4 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4509) KIP1 PF07765.12 KDO21319.1 - 4 7.6 24.9 0.065 13.4 7.0 3.1 3 1 1 4 4 4 0 KIP1-like protein PT PF04886.12 KDO21320.1 - 2.6e-05 23.7 30.8 0.0012 18.4 30.8 2.3 1 1 0 1 1 1 1 PT repeat Elicitin PF00964.17 KDO21320.1 - 0.039 14.1 0.2 0.12 12.5 0.2 1.8 1 1 1 2 2 2 0 Elicitin Elicitin PF00964.17 KDO21321.1 - 0.0071 16.4 0.1 0.78 9.9 0.1 2.6 2 2 0 2 2 2 2 Elicitin TraH_2 PF06871.11 KDO21321.1 - 0.042 13.5 0.1 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 TraH_2 PT PF04886.12 KDO21322.1 - 0.00011 21.6 33.8 0.0055 16.2 33.8 2.3 1 1 0 1 1 1 1 PT repeat Elicitin PF00964.17 KDO21322.1 - 0.052 13.6 0.2 0.16 12.1 0.3 1.8 1 1 1 2 2 2 0 Elicitin GPCR_chapero_1 PF11904.8 KDO21324.1 - 1.2e-30 107.1 0.7 1.9e-30 106.4 0.7 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KDO21324.1 - 5.1e-07 30.2 0.2 1.1e-06 29.2 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21324.1 - 1e-06 29.2 2.1 0.01 16.4 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO21324.1 - 1.2e-06 28.7 2.7 0.00028 21.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO21324.1 - 5.6e-05 23.2 0.3 0.031 14.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KDO21324.1 - 8.2e-05 22.8 1.1 0.11 12.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Glyco_hydro_130 PF04041.13 KDO21324.1 - 0.13 11.1 0.2 3.8 6.3 0.2 2.1 1 1 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase F-protein PF00469.20 KDO21324.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Ank_2 PF12796.7 KDO21325.1 - 1.7e-28 99.0 0.0 4.3e-11 43.3 0.0 4.6 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) TIR_2 PF13676.6 KDO21325.1 - 3.1e-27 95.5 0.1 1.4e-17 64.4 0.0 2.5 2 0 0 2 2 2 2 TIR domain Ank PF00023.30 KDO21325.1 - 3.3e-21 74.7 0.9 0.00091 19.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 KDO21325.1 - 3.8e-21 75.2 2.4 2.3e-09 37.6 0.0 7.6 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21325.1 - 3.8e-19 66.8 2.4 0.00034 20.8 0.0 7.7 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KDO21325.1 - 9.4e-18 64.1 1.6 3.5e-07 30.3 0.0 6.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) TIR PF01582.20 KDO21325.1 - 5.2e-05 23.1 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 KDO21325.1 - 0.22 11.8 0.0 0.56 10.5 0.0 1.7 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Glyco_hydro_72 PF03198.14 KDO21326.1 - 4.2e-07 29.5 0.0 1e-05 25.0 0.0 2.6 2 1 1 3 3 3 1 Glucanosyltransferase PhyH PF05721.13 KDO21328.1 - 2.3e-21 77.1 0.2 4.1e-21 76.2 0.2 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ank_2 PF12796.7 KDO21329.1 - 9.6e-30 103.0 0.6 2.5e-11 44.0 0.0 5.8 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) TIR_2 PF13676.6 KDO21329.1 - 3.3e-25 89.0 0.2 1.5e-17 64.3 0.0 2.7 2 0 0 2 2 2 2 TIR domain Ank_3 PF13606.6 KDO21329.1 - 5.9e-22 75.4 1.2 0.004 17.5 0.0 8.5 7 1 1 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KDO21329.1 - 6.8e-22 77.6 6.1 2.7e-10 40.6 0.1 7.0 4 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21329.1 - 1.4e-17 63.5 2.2 2.5e-05 24.5 0.0 6.9 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO21329.1 - 1.7e-15 56.7 19.2 0.012 16.1 0.1 8.3 10 0 0 10 10 10 5 Ankyrin repeat TIR PF01582.20 KDO21329.1 - 1.4e-05 25.0 0.0 0.00014 21.7 0.0 2.5 3 0 0 3 3 3 1 TIR domain Yip1 PF04893.17 KDO21329.1 - 0.006 16.3 3.3 0.011 15.5 3.3 1.3 1 0 0 1 1 1 1 Yip1 domain REJ PF02010.15 KDO21330.1 - 1.5e-52 179.0 9.9 3.8e-52 177.6 9.9 1.7 1 0 0 1 1 1 1 REJ domain Tetraspanin PF00335.20 KDO21330.1 - 4.5e-26 92.0 75.4 7.8e-11 42.1 3.8 7.0 7 1 0 7 7 7 5 Tetraspanin family EGF_2 PF07974.13 KDO21330.1 - 4.9 7.6 22.8 0.074 13.4 14.0 2.6 3 0 0 3 3 3 0 EGF-like domain Laminin_G_3 PF13385.6 KDO21331.1 - 2.3e-08 34.3 6.5 9.9e-08 32.3 6.5 2.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SBBP PF06739.11 KDO21331.1 - 9.6e-06 25.5 11.3 0.049 13.6 1.3 4.0 3 0 0 3 3 3 3 Beta-propeller repeat zf-MYND PF01753.18 KDO21332.1 - 6.7e-08 32.5 16.1 6.7e-08 32.5 16.1 2.7 2 1 1 3 3 3 1 MYND finger zf-C6H2 PF15801.5 KDO21332.1 - 0.41 11.0 15.0 1.4 9.3 15.0 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF4381 PF14316.6 KDO21339.1 - 1.9 8.7 6.7 0.98 9.7 1.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) NAM-associated PF14303.6 KDO21340.1 - 6.8 7.4 14.8 3.8 8.2 11.8 1.9 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Ribosomal_L7Ae PF01248.26 KDO21341.1 - 3.2e-10 39.6 0.4 6e-10 38.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 KDO21341.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_8 PF13450.6 KDO21342.1 - 1.7e-12 47.4 0.1 1.1e-11 44.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KDO21342.1 - 3.1e-10 39.9 0.0 5.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KDO21342.1 - 6.9e-09 35.7 0.3 9e-08 32.1 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 KDO21342.1 - 0.00012 21.4 0.1 0.00016 20.9 0.1 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase FAD_binding_2 PF00890.24 KDO21342.1 - 0.00044 19.4 0.9 0.0051 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KDO21342.1 - 0.0011 18.3 0.1 0.047 12.9 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO21342.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KDO21342.1 - 0.044 14.4 0.1 0.15 12.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_28 PF02636.17 KDO21344.1 - 0.091 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Laminin_G_3 PF13385.6 KDO21346.1 - 2.7e-15 56.8 1.3 3.4e-15 56.5 0.4 1.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily BNR_4 PF15892.5 KDO21346.1 - 0.0073 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 BNR repeat-containing family member Sel1 PF08238.12 KDO21347.1 - 2e-38 129.9 33.4 5e-07 30.2 0.4 8.6 9 0 0 9 9 9 6 Sel1 repeat TPR_6 PF13174.6 KDO21347.1 - 0.0046 17.5 21.5 1.1 10.1 0.2 6.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO21347.1 - 0.25 11.6 0.1 0.25 11.6 0.1 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO21347.1 - 0.55 11.2 0.0 0.55 11.2 0.0 6.3 8 2 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO21347.1 - 0.72 9.8 0.0 0.72 9.8 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO21347.1 - 1.4 9.3 0.0 1.4 9.3 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO21347.1 - 1.7 8.8 13.9 9.6 6.5 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO21348.1 - 3.6e-37 128.2 0.0 4.2e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21348.1 - 5.5e-14 52.1 0.0 6.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21348.1 - 9.4e-08 31.7 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO21348.1 - 0.006 15.4 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 KDO21348.1 - 0.11 13.2 4.6 0.24 12.1 4.6 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 KDO21348.1 - 0.14 11.1 0.3 0.2 10.5 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FtsJ PF01728.19 KDO21349.1 - 5e-24 85.4 0.0 9.1e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase SNRNP27 PF08648.12 KDO21349.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Globin PF00042.22 KDO21350.1 - 0.00034 21.1 0.1 0.00077 20.0 0.1 1.6 1 1 0 1 1 1 1 Globin TusA PF01206.17 KDO21350.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA HSF_DNA-bind PF00447.17 KDO21354.1 - 2.9e-29 101.5 0.4 4.2e-29 101.0 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HD_2 PF12917.7 KDO21354.1 - 0.02 14.6 0.2 0.03 14.1 0.2 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme AKAP2_C PF15304.6 KDO21354.1 - 0.028 13.7 1.5 0.035 13.4 1.5 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus EF-hand_7 PF13499.6 KDO21356.1 - 3.3e-40 136.4 26.1 1.5e-09 38.2 0.0 9.0 8 1 1 9 9 9 7 EF-hand domain pair EF-hand_6 PF13405.6 KDO21356.1 - 2.1e-32 108.3 20.5 3.1e-06 26.7 0.1 10.8 11 0 0 11 11 11 8 EF-hand domain EF-hand_1 PF00036.32 KDO21356.1 - 4.4e-30 100.9 30.0 3.9e-06 26.0 0.2 10.3 10 0 0 10 10 10 7 EF hand EF-hand_8 PF13833.6 KDO21356.1 - 3.4e-25 87.6 15.2 4.8e-09 35.9 0.0 8.9 8 2 2 10 10 10 5 EF-hand domain pair EF-hand_5 PF13202.6 KDO21356.1 - 8.7e-20 69.3 22.9 0.0048 16.3 0.2 8.0 8 0 0 8 8 8 6 EF hand EF-hand_14 PF17959.1 KDO21356.1 - 0.00075 19.8 1.9 25 5.3 0.0 5.4 7 0 0 7 7 6 0 EF-hand domain EF-hand_4 PF12763.7 KDO21356.1 - 0.0062 16.5 1.1 24 5.0 0.1 4.4 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KDO21356.1 - 0.014 16.3 0.1 41 5.1 0.0 3.9 4 0 0 4 4 3 0 EF-hand domain TerB PF05099.13 KDO21356.1 - 0.031 14.2 10.2 1.2 9.1 0.1 5.5 5 2 1 6 6 6 0 Tellurite resistance protein TerB HATPase_c_3 PF13589.6 KDO21356.1 - 0.085 12.7 0.0 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_9 PF14658.6 KDO21356.1 - 0.09 13.1 2.9 3.2 8.1 0.1 4.3 5 0 0 5 5 4 0 EF-hand domain Neil1-DNA_bind PF09292.10 KDO21356.1 - 0.92 9.5 3.3 30 4.7 0.1 2.9 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind EF-hand_7 PF13499.6 KDO21358.1 - 4.4e-23 81.5 8.3 8.9e-12 45.3 1.7 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO21358.1 - 1.2e-20 71.4 9.8 5.9e-05 22.3 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KDO21358.1 - 2.7e-19 68.7 7.3 2.4e-09 36.9 0.1 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO21358.1 - 3.5e-18 63.9 6.7 1.5e-05 24.6 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO21358.1 - 1.9e-12 46.1 10.1 0.0012 18.3 0.5 4.7 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 KDO21358.1 - 1.6e-05 25.2 2.0 0.083 13.2 0.3 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO21358.1 - 0.00025 21.0 6.0 0.057 13.4 0.6 3.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand ORC5_C PF14630.6 KDO21358.1 - 0.011 15.3 1.6 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus EF-hand_11 PF08976.11 KDO21358.1 - 0.13 13.2 0.3 10 7.1 0.0 2.6 1 1 0 2 2 2 0 EF-hand domain PP1c_bdg PF10488.9 KDO21359.1 - 0.077 12.5 5.2 0.13 11.7 5.2 1.4 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Macoilin PF09726.9 KDO21359.1 - 0.33 9.5 7.1 0.38 9.2 7.1 1.3 1 0 0 1 1 1 0 Macoilin family DUF948 PF06103.11 KDO21359.1 - 0.35 11.2 4.2 0.43 10.9 0.4 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 KDO21359.1 - 0.41 10.4 6.2 3.1 7.7 3.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Nsp1_C PF05064.13 KDO21359.1 - 1.8 8.4 4.3 0.86 9.4 1.3 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region bZIP_2 PF07716.15 KDO21359.1 - 1.9 8.6 6.4 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_18 PF00704.28 KDO21360.1 - 2.9e-07 30.5 0.0 1.5e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Peptidase_S10 PF00450.22 KDO21362.1 - 5.5e-122 408.2 0.1 6.9e-122 407.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KDO21362.1 - 0.015 15.9 1.7 1.3 9.6 1.7 2.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1769 PF08588.10 KDO21362.1 - 0.036 14.3 0.0 0.18 12.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1769) SDF PF00375.18 KDO21363.1 - 4.9e-62 210.2 34.1 9.4e-34 117.1 12.5 2.5 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO21364.1 - 4.2e-63 213.7 31.3 1.5e-33 116.4 11.9 2.8 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family DUF3593 PF12159.8 KDO21364.1 - 3.3 7.8 6.8 12 6.0 2.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3593) Glycos_transf_1 PF00534.20 KDO21365.1 - 1.3e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO21365.1 - 1.4e-06 28.8 0.0 3.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO21365.1 - 0.0098 16.3 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SDF PF00375.18 KDO21366.1 - 9.5e-55 186.2 39.6 8.1e-29 100.8 16.2 3.0 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family Complex1_LYR PF05347.15 KDO21367.1 - 5.2e-06 26.4 0.1 1e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) GATase_7 PF13537.6 KDO21367.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain zf-C2H2_assoc3 PF16637.5 KDO21367.1 - 0.13 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz 5_3_exonuc_N PF02739.16 KDO21369.1 - 1.2e-33 116.3 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KDO21369.1 - 2.7e-10 40.7 0.0 4.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold ABC_tran PF00005.27 KDO21371.1 - 3.7e-35 121.4 0.1 4.8e-24 85.4 0.0 5.3 4 2 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 KDO21371.1 - 3.7e-09 36.8 20.3 0.00018 21.4 0.1 4.9 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KDO21371.1 - 1.5e-06 28.1 9.3 1.5e-06 28.1 9.3 5.9 4 2 1 5 5 3 1 ABC transporter AAA_29 PF13555.6 KDO21371.1 - 0.00024 20.8 0.1 0.0033 17.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO21371.1 - 0.0011 19.3 0.0 0.0049 17.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KDO21371.1 - 0.0019 18.1 1.5 0.0035 17.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KDO21371.1 - 0.0026 18.3 0.0 0.0026 18.3 0.0 5.5 3 1 1 5 5 2 1 AAA domain AAA_15 PF13175.6 KDO21371.1 - 0.013 15.2 0.0 0.013 15.2 0.0 4.2 4 1 0 4 4 3 0 AAA ATPase domain AAA_16 PF13191.6 KDO21371.1 - 0.021 15.2 4.2 0.054 13.9 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 KDO21371.1 - 0.04 14.0 0.0 0.04 14.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 KDO21371.1 - 0.045 13.2 0.0 0.045 13.2 0.0 3.8 3 1 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KDO21371.1 - 0.084 13.3 1.0 0.39 11.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KDO21371.1 - 0.1 13.0 0.0 0.46 10.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KDO21371.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KDO21371.1 - 0.61 10.6 0.0 0.61 10.6 0.0 4.6 4 2 0 4 4 3 0 AAA domain Voltage_CLC PF00654.20 KDO21372.1 - 2.1e-83 280.5 26.1 2.1e-83 280.5 26.1 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KDO21372.1 - 4.1e-08 33.5 0.0 0.0005 20.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain Haem_degrading PF03928.14 KDO21372.1 - 0.072 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Haem-degrading MatE PF01554.18 KDO21373.1 - 2.3e-50 170.4 31.9 9.4e-28 96.9 13.1 2.4 2 0 0 2 2 2 2 MatE Cluap1 PF10234.9 KDO21374.1 - 1.9e-97 325.8 7.8 3.8e-97 324.9 7.8 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lebercilin PF15619.6 KDO21374.1 - 6.2e-05 22.7 17.8 0.00013 21.7 17.8 1.5 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 KDO21374.1 - 0.23 9.4 2.1 0.24 9.3 0.9 1.6 1 1 0 1 1 1 0 Prominin DivIC PF04977.15 KDO21374.1 - 2.2 8.1 10.5 0.4 10.5 1.3 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF2951 PF11166.8 KDO21374.1 - 4.2 7.6 6.7 7.6 6.8 5.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) RecG_N PF17190.4 KDO21374.1 - 4.7 8.0 12.6 4.7 8.0 8.4 2.6 1 1 1 2 2 2 0 RecG N-terminal helical domain DUF5595 PF18077.1 KDO21374.1 - 9.8 6.3 13.5 5.9 7.1 1.2 4.0 2 1 3 5 5 5 0 Domain of unknown function (DUF5595) Syja_N PF02383.18 KDO21375.1 - 1.3e-58 198.9 0.0 5e-58 196.9 0.0 1.9 1 1 0 1 1 1 1 SacI homology domain WYL PF13280.6 KDO21375.1 - 0.022 14.8 0.2 0.063 13.3 0.1 1.7 2 0 0 2 2 2 0 WYL domain PB1 PF00564.24 KDO21376.1 - 4.9e-07 29.6 0.0 1.6e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Glyco_transf_43 PF03360.16 KDO21376.1 - 0.00099 19.0 0.4 0.008 16.0 0.2 2.2 2 1 0 2 2 2 1 Glycosyltransferase family 43 CUE PF02845.16 KDO21376.1 - 0.0013 18.3 0.2 0.0013 18.3 0.2 2.1 2 0 0 2 2 2 1 CUE domain Phasin_2 PF09361.10 KDO21376.1 - 0.0047 17.2 10.4 0.0071 16.6 1.3 2.5 1 1 1 2 2 2 2 Phasin protein p450 PF00067.22 KDO21376.1 - 0.072 11.8 0.9 0.16 10.7 0.8 1.4 1 1 0 1 1 1 0 Cytochrome P450 DUF1351 PF07083.11 KDO21376.1 - 0.26 11.0 14.0 0.48 10.2 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) DNApol_Exo PF18136.1 KDO21376.1 - 0.27 10.4 5.3 0.41 9.7 5.3 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain cwf18 PF08315.12 KDO21377.1 - 4e-17 63.1 3.0 4e-17 63.1 3.0 2.4 2 1 1 3 3 3 1 cwf18 pre-mRNA splicing factor CNOT1_HEAT PF16418.5 KDO21377.1 - 0.0092 16.1 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat HU-CCDC81_euk_2 PF18289.1 KDO21378.1 - 8.5e-15 54.7 0.0 2.2e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 KDO21378.1 - 4.1e-10 39.7 0.0 1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 DUF1863 PF08937.11 KDO21378.1 - 0.64 10.3 5.8 7.8 6.8 1.2 2.6 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Methyltransf_PK PF05891.12 KDO21379.1 - 1.4e-73 247.0 0.0 1.8e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KDO21379.1 - 3.3e-10 40.5 0.0 6.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO21379.1 - 5.8e-10 39.7 0.0 9.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO21379.1 - 1.9e-07 31.7 0.0 3.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KDO21379.1 - 5.4e-07 29.1 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KDO21379.1 - 6.9e-07 29.3 0.0 1.3e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO21379.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fer4_5 PF12801.7 KDO21379.1 - 0.09 12.7 0.5 0.17 11.9 0.5 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Methyltransf_3 PF01596.17 KDO21379.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Kelch_4 PF13418.6 KDO21380.1 - 5.3e-19 68.0 4.5 6.8e-06 26.0 0.0 6.8 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO21380.1 - 5.7e-15 54.9 4.1 0.00023 21.1 0.0 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KDO21380.1 - 3.8e-13 49.2 1.8 7e-06 26.1 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 KDO21380.1 - 5.3e-10 38.7 5.0 0.01 15.4 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KDO21380.1 - 2.4e-05 24.1 3.1 0.092 12.8 0.0 5.4 6 1 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 KDO21380.1 - 4.4e-05 23.6 18.5 0.0016 18.6 0.0 6.3 7 1 0 7 7 7 2 Galactose oxidase, central domain Mis12 PF05859.12 KDO21380.1 - 0.16 12.1 0.7 0.49 10.5 0.1 1.9 2 0 0 2 2 2 0 Mis12 protein DUF2046 PF09755.9 KDO21380.1 - 0.59 9.3 4.4 4.8 6.3 4.4 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Cnn_1N PF07989.11 KDO21380.1 - 4 7.7 5.7 6.5 7.0 1.7 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 KDO21380.1 - 5.2 6.8 8.6 0.99 9.2 2.8 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 KDO21380.1 - 5.4 7.7 5.5 1.8 9.3 1.5 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Ricin_B_lectin PF00652.22 KDO21381.1 - 1.2e-12 48.1 3.1 1.8e-11 44.4 1.1 3.0 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Trypsin_2 PF13365.6 KDO21381.1 - 1.3e-12 48.9 0.2 7.9e-12 46.3 0.0 2.3 3 0 0 3 3 3 1 Trypsin-like peptidase domain RicinB_lectin_2 PF14200.6 KDO21381.1 - 9e-06 26.3 1.0 0.00038 21.1 0.3 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Trypsin PF00089.26 KDO21381.1 - 4.3e-05 23.4 0.6 7.2e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Trypsin DUF2778 PF10908.8 KDO21381.1 - 0.08 13.2 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) CDtoxinA PF03498.14 KDO21381.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.0 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Y_phosphatase2 PF03162.13 KDO21382.1 - 3.8e-55 186.0 0.0 4.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KDO21382.1 - 1.1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KDO21382.1 - 0.00062 19.6 0.0 0.00084 19.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO21382.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PB1 PF00564.24 KDO21383.1 - 7e-06 25.9 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain UBA_4 PF14555.6 KDO21383.1 - 0.0083 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain AD PF09793.9 KDO21383.1 - 0.1 12.7 0.4 2 8.6 0.1 2.4 1 1 1 2 2 2 0 Anticodon-binding domain UBA PF00627.31 KDO21383.1 - 0.48 10.4 0.1 0.48 10.4 0.1 1.9 2 0 0 2 2 2 0 UBA/TS-N domain HMG_box PF00505.19 KDO21384.1 - 2e-51 172.3 23.4 1.9e-12 47.4 0.0 5.6 5 1 0 5 5 5 5 HMG (high mobility group) box HMG_box_2 PF09011.10 KDO21384.1 - 1.4e-27 96.1 21.9 5.9e-06 26.8 1.2 5.2 5 0 0 5 5 5 5 HMG-box domain Protamine_like PF06382.11 KDO21384.1 - 8.5e-06 26.0 13.6 0.081 13.1 0.0 4.2 2 1 2 4 4 4 2 Protamine and protamine like HMG_box_5 PF14887.6 KDO21384.1 - 0.0007 19.5 9.8 6.5 6.8 0.0 4.4 4 0 0 4 4 4 3 HMG (high mobility group) box 5 Unstab_antitox PF09720.10 KDO21384.1 - 0.05 13.7 2.5 0.65 10.1 0.6 3.2 2 0 0 2 2 2 0 Putative addiction module component LPD11 PF18824.1 KDO21384.1 - 0.086 12.9 5.4 5.1 7.2 0.0 4.6 5 0 0 5 5 5 0 Large polyvalent protein-associated domain 11 COX4 PF02936.14 KDO21384.1 - 0.42 10.6 12.9 6.9 6.7 0.2 5.0 5 0 0 5 5 5 0 Cytochrome c oxidase subunit IV DUF3742 PF12553.8 KDO21384.1 - 0.65 10.1 4.0 6.6 6.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) Mob1_phocein PF03637.17 KDO21385.1 - 1.7e-09 38.0 2.1 2e-08 34.4 1.4 2.0 1 1 1 2 2 2 2 Mob1/phocein family Cupin_8 PF13621.6 KDO21386.1 - 1.5e-28 100.2 0.1 2e-28 99.8 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO21386.1 - 7.5e-06 25.6 0.8 3.2e-05 23.5 0.0 2.1 2 1 1 3 3 3 1 Cupin superfamily protein JmjC PF02373.22 KDO21386.1 - 0.042 14.3 0.0 0.074 13.5 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase GPI PF06560.11 KDO21386.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) C2 PF00168.30 KDO21387.1 - 7.6e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 KDO21387.1 - 6.7e-06 26.7 0.0 1.8 9.2 0.0 4.0 4 0 0 4 4 4 3 Putative heavy-metal-binding DUF1635 PF07795.11 KDO21387.1 - 7.7 6.3 7.9 0.28 11.0 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Ifi-6-16 PF06140.13 KDO21388.1 - 6.2e-20 70.9 41.7 9.2e-20 70.4 41.7 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Myb_DNA-bind_4 PF13837.6 KDO21388.1 - 0.013 15.8 0.2 0.023 15.1 0.2 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF4699 PF15770.5 KDO21388.1 - 0.059 13.1 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Ifi-6-16 PF06140.13 KDO21390.1 - 5.3e-20 71.1 39.8 8.8e-20 70.4 39.8 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family TFIIS_M PF07500.14 KDO21392.1 - 2.4e-18 66.6 5.2 2.4e-18 66.6 5.2 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KDO21392.1 - 2.8e-17 62.3 3.8 4.6e-17 61.6 3.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KDO21392.1 - 1.1e-13 50.9 0.7 5e-13 48.9 0.7 2.2 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 KDO21392.1 - 0.022 14.7 1.0 0.055 13.4 1.0 1.7 1 0 0 1 1 1 0 DNL zinc finger zinc_ribbon_6 PF14599.6 KDO21392.1 - 8.2 6.5 8.8 5.4 7.1 0.3 3.4 4 0 0 4 4 4 0 Zinc-ribbon IF4E PF01652.18 KDO21394.1 - 1.4e-41 141.9 0.1 1.7e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Lactonase PF10282.9 KDO21395.1 - 0.033 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DPPIV_N PF00930.21 KDO21395.1 - 0.1 11.3 0.0 0.55 8.9 0.0 1.9 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Choline_transpo PF04515.12 KDO21396.1 - 3e-71 240.3 20.6 3.4e-71 240.1 20.6 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF2388 PF09498.10 KDO21396.1 - 0.2 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) TssN PF17555.2 KDO21396.1 - 0.77 9.1 7.0 2 7.7 7.0 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssN Arm PF00514.23 KDO21399.1 - 3.4e-82 268.2 20.2 5.4e-13 48.5 0.0 9.4 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO21399.1 - 1.2e-25 89.6 0.1 7.6e-07 29.4 0.0 5.3 1 1 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.6 KDO21399.1 - 5.2e-25 87.5 9.3 1.7e-10 41.2 0.0 7.3 6 2 0 6 6 6 4 HEAT-like repeat HEAT PF02985.22 KDO21399.1 - 1.4e-20 71.6 4.7 3.8e-05 23.6 0.0 8.5 9 0 0 9 9 9 5 HEAT repeat Arm_3 PF16186.5 KDO21399.1 - 1.7e-17 62.7 0.0 1.2e-16 60.0 0.3 2.1 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 KDO21399.1 - 2.2e-15 56.9 1.1 4.7e-15 55.8 1.1 1.6 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.20 KDO21399.1 - 8.8e-05 21.2 0.1 0.058 11.9 0.1 3.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KDO21399.1 - 0.00018 21.6 0.0 0.038 14.1 0.0 3.8 4 0 0 4 4 4 1 V-ATPase subunit H Arm_2 PF04826.13 KDO21399.1 - 0.00023 20.7 0.0 0.35 10.3 0.1 2.8 1 1 1 2 2 2 2 Armadillo-like RICTOR_V PF14668.6 KDO21399.1 - 0.00044 20.4 0.6 7.5 6.9 0.1 4.3 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KDO21399.1 - 0.00094 19.6 1.8 0.99 10.3 0.1 5.1 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat IFRD PF05004.13 KDO21399.1 - 0.018 14.2 0.3 0.96 8.5 0.0 3.4 2 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 KDO21399.1 - 0.028 14.4 0.4 1.3 9.1 0.0 3.1 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain YiaAB PF05360.14 KDO21401.1 - 0.077 13.3 1.4 0.13 12.5 0.3 2.0 2 0 0 2 2 2 0 yiaA/B two helix domain Glyco_transf_29 PF00777.18 KDO21401.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Ysc84 PF04366.12 KDO21403.1 - 9.2e-37 125.7 0.5 1.5e-36 125.0 0.5 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator zf-UBR PF02207.20 KDO21404.1 - 1.6e-17 63.5 17.0 1.6e-17 63.5 17.0 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) FlaC_arch PF05377.11 KDO21405.1 - 1.5e-05 25.3 0.2 0.016 15.6 0.1 2.2 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) HALZ PF02183.18 KDO21405.1 - 0.0095 16.1 0.6 0.018 15.2 0.6 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper MbeD_MobD PF04899.12 KDO21405.1 - 0.018 15.2 2.7 0.15 12.2 2.7 2.2 1 1 0 1 1 1 0 MbeD/MobD like DUF1640 PF07798.11 KDO21405.1 - 0.033 14.2 0.6 0.036 14.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF5320 PF17253.2 KDO21405.1 - 0.088 13.9 1.0 0.22 12.6 0.5 1.7 1 1 0 2 2 2 0 Family of unknown function (DUF5320) CCDC-167 PF15188.6 KDO21405.1 - 0.11 12.9 3.1 0.59 10.5 3.1 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 KDO21405.1 - 0.13 12.0 0.3 0.13 12.0 0.3 1.8 3 0 0 3 3 3 0 Septum formation initiator CENP-F_N PF10481.9 KDO21406.1 - 0.0016 18.1 4.3 0.0016 18.1 4.3 1.6 1 1 0 1 1 1 1 Cenp-F N-terminal domain MMTV_SAg PF01054.17 KDO21406.1 - 0.019 14.5 0.2 0.028 13.9 0.2 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen CCDC74_C PF14917.6 KDO21406.1 - 0.91 10.1 9.0 4.4 7.9 0.3 3.1 2 1 1 3 3 3 0 Coiled coil protein 74, C terminal GAF_2 PF13185.6 KDO21407.1 - 9.9e-05 22.7 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KDO21407.1 - 0.00025 21.7 0.1 0.00046 20.8 0.0 1.6 1 1 0 1 1 1 1 GAF domain EF-hand_7 PF13499.6 KDO21408.1 - 1.7e-39 134.1 1.6 1.3e-08 35.2 0.1 7.9 7 1 0 7 7 7 5 EF-hand domain pair EF-hand_6 PF13405.6 KDO21408.1 - 1.6e-26 89.9 3.9 0.014 15.2 0.0 10.7 10 0 0 10 10 10 6 EF-hand domain EF-hand_1 PF00036.32 KDO21408.1 - 1.6e-24 83.6 0.0 0.013 15.0 0.0 10.3 11 0 0 11 11 11 6 EF hand EF-hand_8 PF13833.6 KDO21408.1 - 2e-20 72.4 2.2 0.00027 20.7 0.0 8.1 8 2 2 10 10 10 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO21408.1 - 2e-10 39.7 0.0 0.096 12.2 0.0 6.9 7 0 0 7 7 7 3 EF hand EF-hand_11 PF08976.11 KDO21408.1 - 7.1e-10 39.7 1.6 1.6 9.7 0.0 6.8 8 0 0 8 8 8 2 EF-hand domain DUF5580 PF17743.1 KDO21408.1 - 0.00013 20.6 2.8 0.11 11.0 0.1 4.6 3 2 1 4 4 4 1 Family of unknown function (DUF5580) vWF_A PF12450.8 KDO21408.1 - 0.00091 19.1 0.1 0.0055 16.6 0.1 2.2 2 0 0 2 2 2 1 von Willebrand factor Peptidase_C3G PF12381.8 KDO21408.1 - 0.062 12.7 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Tungro spherical virus-type peptidase dbPDZ_assoc PF16610.5 KDO21408.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Glyco_transf_4 PF13439.6 KDO21409.1 - 4.5e-07 30.0 0.1 1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KDO21409.1 - 5.8e-07 30.0 0.0 3.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KDO21409.1 - 5.8e-07 29.2 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KDO21409.1 - 1.3e-06 28.9 0.7 4e-06 27.4 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain HSF_DNA-bind PF00447.17 KDO21410.1 - 1.1e-19 70.8 0.9 1.8e-19 70.1 0.9 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Agenet PF05641.12 KDO21411.1 - 1.2e-06 28.8 0.0 3.4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Agenet domain TUDOR_5 PF18359.1 KDO21411.1 - 0.00014 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 KDO21411.1 - 0.00039 20.2 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 KDO21411.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Tudor_2 PF18104.1 KDO21411.1 - 0.0048 16.5 0.3 0.0089 15.7 0.3 1.4 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 KDO21411.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 KDO21411.1 - 0.046 13.8 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF4537 PF15057.6 KDO21411.1 - 0.053 13.5 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) HAS-barrel PF09378.10 KDO21411.1 - 0.11 12.6 0.4 1.9 8.7 0.4 2.3 1 1 0 1 1 1 0 HAS barrel domain SpoIIIAH PF12685.7 KDO21411.1 - 0.17 11.7 10.8 0.34 10.7 10.8 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein MscS_TM PF12794.7 KDO21411.1 - 0.22 10.4 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ATP-synt_G PF04718.15 KDO21411.1 - 0.76 10.6 4.7 1.7 9.5 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial ATP synthase g subunit NigD_N PF12667.7 KDO21411.1 - 0.81 9.8 3.3 2.6 8.2 0.1 2.8 2 1 1 3 3 3 0 NigD-like N-terminal OB domain MRI PF15325.6 KDO21411.1 - 2.5 9.3 11.3 0.075 14.1 1.9 2.4 2 1 0 2 2 2 0 Modulator of retrovirus infection FancD2 PF14631.6 KDO21411.1 - 2.6 5.4 5.7 3.5 4.9 5.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease TMEM208_SND2 PF05620.11 KDO21411.1 - 9.2 6.0 7.1 12 5.6 0.6 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 GAF PF01590.26 KDO21412.1 - 1e-10 42.4 0.1 6.3e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KDO21412.1 - 4.6e-08 33.5 0.1 0.0094 16.2 0.0 2.2 2 0 0 2 2 2 2 GAF domain RNR_Alpha PF17975.1 KDO21413.1 - 3.4e-39 133.4 0.1 5.8e-39 132.7 0.1 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 KDO21413.1 - 2.5e-11 42.9 0.0 4.3e-05 22.3 0.0 3.1 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain G6PD_C PF02781.16 KDO21414.1 - 1.1e-98 330.1 0.0 1.4e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KDO21414.1 - 7.1e-53 179.8 0.0 1.1e-52 179.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.14 KDO21414.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucanosyltransferase Kinesin PF00225.23 KDO21416.1 - 9.9e-08 31.3 5.0 0.0062 15.5 0.3 4.2 3 1 0 3 3 3 2 Kinesin motor domain TMF_TATA_bd PF12325.8 KDO21416.1 - 0.0041 17.3 26.7 0.0069 16.6 8.3 3.7 3 1 1 4 4 3 2 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KDO21416.1 - 0.018 15.1 2.8 0.018 15.1 2.8 4.2 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KDO21416.1 - 0.018 15.3 4.1 0.018 15.3 4.1 3.5 2 1 0 3 3 3 0 Tup N-terminal YabA PF06156.13 KDO21416.1 - 0.069 13.8 21.2 1.2 9.8 1.5 4.3 2 1 1 3 3 3 0 Initiation control protein YabA VWA_2 PF13519.6 KDO21416.1 - 0.16 12.6 2.1 0.61 10.8 1.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain ZapB PF06005.12 KDO21416.1 - 0.53 10.8 30.3 5.6 7.5 3.6 4.7 2 1 2 4 4 4 0 Cell division protein ZapB TSC22 PF01166.18 KDO21416.1 - 0.74 10.2 11.9 0.78 10.1 0.9 4.4 2 2 0 3 3 3 0 TSC-22/dip/bun family DUF3037 PF11236.8 KDO21416.1 - 1.3 9.5 6.3 26 5.2 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) Spc29 PF17082.5 KDO21416.1 - 3.1 7.6 10.3 1.1 9.1 3.8 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 ATG16 PF08614.11 KDO21416.1 - 3.3 7.9 45.6 0.069 13.4 25.7 3.2 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) Acetyltransf_10 PF13673.7 KDO21417.1 - 2.6e-13 50.0 0.0 3.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO21417.1 - 7.9e-11 42.2 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO21417.1 - 2.1e-09 37.6 0.0 2.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KDO21417.1 - 0.00047 20.2 0.1 0.0037 17.3 0.1 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NodA PF02474.15 KDO21417.1 - 0.022 14.4 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein A (NodA) FR47 PF08445.10 KDO21417.1 - 0.049 13.6 0.2 0.1 12.5 0.2 1.7 1 1 0 1 1 1 0 FR47-like protein PanZ PF12568.8 KDO21417.1 - 0.056 13.2 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Rft-1 PF04506.13 KDO21418.1 - 7e-101 338.5 14.3 8.6e-101 338.2 14.3 1.0 1 0 0 1 1 1 1 Rft protein Pkinase PF00069.25 KDO21419.1 - 3.8e-74 249.4 0.0 4.7e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21419.1 - 1.1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21419.1 - 0.0004 19.8 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO21419.1 - 0.0016 17.3 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO21419.1 - 0.0019 18.2 0.0 0.066 13.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mt_ATP-synt_B PF05405.14 KDO21420.1 - 1.1e-16 61.0 0.6 1.1e-16 61.0 0.6 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) COG5 PF10392.9 KDO21420.1 - 0.038 14.2 2.0 0.076 13.2 2.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DPRP PF04244.13 KDO21420.1 - 0.1 12.4 1.5 0.34 10.8 0.0 2.0 1 1 1 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein MYO10_CC PF16735.5 KDO21420.1 - 0.48 10.6 3.8 17 5.6 0.1 2.8 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain Peptidase_S46 PF10459.9 KDO21420.1 - 1.5 7.4 9.0 1.9 7.0 9.0 1.1 1 0 0 1 1 1 0 Peptidase S46 CENP-H PF05837.12 KDO21420.1 - 8 6.9 8.5 2.5 8.6 3.9 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3586 PF12131.8 KDO21422.1 - 0.11 12.7 15.3 1.3 9.3 2.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3586) DUF2807 PF10988.8 KDO21423.1 - 6e-22 78.3 10.9 1.6e-12 47.6 0.9 2.2 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain Syndecan PF01034.20 KDO21423.1 - 0.051 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain MLANA PF14991.6 KDO21423.1 - 0.07 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Fez1 PF06818.15 KDO21424.1 - 0.0073 16.8 20.9 0.094 13.2 20.9 2.2 1 1 0 1 1 1 1 Fez1 Hydantoinase_B PF02538.14 KDO21424.1 - 0.19 10.1 2.3 0.25 9.7 2.3 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase ATG16 PF08614.11 KDO21424.1 - 0.39 10.9 30.7 0.059 13.6 8.7 3.6 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KDO21424.1 - 0.41 10.0 9.7 0.15 11.4 6.9 1.7 1 1 1 2 2 2 0 FAM76 protein DUF4795 PF16043.5 KDO21424.1 - 1.1 8.8 12.8 1.5 8.4 0.2 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) FlxA PF14282.6 KDO21424.1 - 1.3 9.1 10.0 16 5.5 5.4 3.3 2 1 1 3 3 3 0 FlxA-like protein Tup_N PF08581.10 KDO21424.1 - 4.1 7.8 18.3 0.71 10.2 5.5 3.5 2 1 1 3 3 3 0 Tup N-terminal Striatin PF08232.12 KDO21424.1 - 8.2 7.0 17.6 17 5.9 5.6 3.0 1 1 1 2 2 2 0 Striatin family EamA PF00892.20 KDO21425.1 - 3.8e-12 46.5 14.5 3.8e-12 46.5 14.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KDO21425.1 - 0.23 10.6 10.8 0.023 13.8 1.6 2.3 1 1 0 2 2 2 0 Nucleotide-sugar transporter Acetyltransf_1 PF00583.25 KDO21426.1 - 1.4e-16 60.7 0.0 1.8e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO21426.1 - 1.4e-11 44.4 0.0 1.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO21426.1 - 9.8e-11 41.9 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KDO21426.1 - 3.9e-07 29.9 0.0 4.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 KDO21426.1 - 1e-05 25.7 0.0 1.2e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO21426.1 - 7.9e-05 22.7 0.0 0.00012 22.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO21426.1 - 0.00023 21.1 0.1 0.00036 20.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 KDO21426.1 - 0.00086 19.5 0.8 0.0012 19.0 0.8 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO21426.1 - 0.0023 18.6 0.0 0.0028 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO21426.1 - 0.008 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4821 PF16092.5 KDO21426.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Sld5 PF05916.11 KDO21427.1 - 8.5e-06 26.2 0.1 2.3e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 GINS complex protein DUF2222 PF09984.9 KDO21427.1 - 0.12 12.3 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) Prok-JAB PF14464.6 KDO21427.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain MFS_1 PF07690.16 KDO21428.1 - 1.4e-32 113.0 41.9 5.6e-29 101.2 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KDO21428.1 - 2.4e-07 30.0 19.0 9.2e-06 24.7 17.8 2.4 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 KDO21428.1 - 6e-07 28.7 25.8 9e-07 28.1 7.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO21429.1 - 2.3e-34 118.9 26.9 5.4e-28 97.9 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO21429.1 - 9.1e-07 28.1 21.9 2e-06 27.0 7.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KDO21429.1 - 2.3e-06 26.8 13.8 0.00035 19.6 13.8 2.3 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 KDO21429.1 - 0.56 8.5 13.6 0.084 11.3 0.3 2.5 2 1 1 3 3 3 0 Transmembrane secretion effector Transgly_assoc PF04226.13 KDO21429.1 - 6.9 7.0 10.2 14 6.0 0.4 3.5 3 0 0 3 3 3 0 Transglycosylase associated protein EAP30 PF04157.16 KDO21430.1 - 4.1e-69 232.5 0.3 4.6e-69 232.3 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Glyco_hyd_65N_2 PF14498.6 KDO21431.1 - 0.2 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Arf PF00025.21 KDO21432.1 - 3.9e-60 202.3 0.0 4.3e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO21432.1 - 1.9e-10 40.4 0.0 8.1e-07 28.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KDO21432.1 - 3.7e-07 30.4 0.0 8.2e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO21432.1 - 7.4e-07 28.9 0.0 8.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KDO21432.1 - 1.2e-06 28.6 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KDO21432.1 - 5.7e-06 25.9 0.0 7.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KDO21432.1 - 0.0018 17.7 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KDO21432.1 - 0.011 15.2 0.0 0.45 10.0 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KDO21432.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF5319 PF17252.2 KDO21432.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Antibiotic_NAT PF02522.14 KDO21432.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Pkinase PF00069.25 KDO21434.1 - 9.8e-45 153.0 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21434.1 - 1.4e-24 86.8 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO21434.1 - 0.00014 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DSPc PF00782.20 KDO21435.1 - 1.6e-17 63.6 0.0 2.3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO21435.1 - 4.8e-05 23.0 0.0 5.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO21435.1 - 0.0058 16.8 0.1 0.0098 16.0 0.1 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 KDO21435.1 - 0.027 14.1 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 KDO21435.1 - 0.027 14.7 0.1 0.059 13.7 0.1 1.5 1 1 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KDO21435.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KDO21435.1 - 0.18 11.3 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_16 PF10294.9 KDO21436.1 - 1.9e-23 83.1 0.0 2.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO21436.1 - 0.0036 16.7 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO21436.1 - 0.1 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Torus PF16131.5 KDO21437.1 - 1.1e-33 116.1 1.4 4.7e-33 114.1 0.9 2.3 2 0 0 2 2 2 1 Torus domain WW PF00397.26 KDO21437.1 - 1.6e-09 37.6 1.9 3.2e-09 36.7 1.9 1.5 1 0 0 1 1 1 1 WW domain RRM_1 PF00076.22 KDO21437.1 - 3e-08 33.3 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KDO21437.1 - 0.0002 20.6 3.3 0.00038 19.7 3.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc-ribbon_6 PF10005.9 KDO21437.1 - 0.011 16.4 0.6 0.036 14.7 0.6 1.9 1 0 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.8 KDO21437.1 - 0.017 15.0 3.7 0.045 13.6 3.7 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1952 PF09189.10 KDO21437.1 - 0.024 14.5 0.1 0.062 13.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1952) zf_CCCH_4 PF18345.1 KDO21437.1 - 0.026 14.6 5.6 0.061 13.4 5.6 1.7 1 0 0 1 1 1 0 Zinc finger domain RRM_5 PF13893.6 KDO21437.1 - 0.031 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) QueC PF06508.13 KDO21437.1 - 8.3 5.8 7.5 0.24 10.9 0.9 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC LigB PF02900.18 KDO21438.1 - 3.8e-36 124.6 0.0 4.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase cNMP_binding PF00027.29 KDO21440.1 - 3.7e-21 75.0 0.0 1e-12 48.0 0.0 4.9 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Glyco_hydro_65C PF03633.15 KDO21440.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain LigB PF02900.18 KDO21441.1 - 3.1e-09 36.3 0.0 3.5e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LigB PF02900.18 KDO21442.1 - 1.5e-29 102.9 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.24 KDO21443.1 - 1e-06 27.9 0.2 1.7e-06 27.2 0.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PT-VENN PF04829.13 KDO21443.1 - 0.23 11.6 5.5 3.9 7.6 0.2 2.5 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Torus PF16131.5 KDO21444.1 - 1.5e-08 35.3 0.0 2.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KDO21444.1 - 4.1e-06 26.6 1.5 9.7e-06 25.5 1.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KDO21444.1 - 0.00042 20.2 2.2 0.00042 20.2 2.2 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO21444.1 - 0.052 13.4 4.0 0.12 12.2 4.0 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger FYVE PF01363.21 KDO21444.1 - 6 7.1 10.7 0.21 11.8 4.1 2.0 2 1 0 3 3 3 0 FYVE zinc finger LRR_8 PF13855.6 KDO21445.1 - 0.017 14.9 3.0 0.017 14.9 3.0 3.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KDO21445.1 - 0.018 15.4 13.0 0.074 13.5 5.7 3.9 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Mce4_CUP1 PF11887.8 KDO21446.1 - 0.039 13.4 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative EGF_2 PF07974.13 KDO21447.1 - 5.8e-14 52.2 55.9 8e-06 26.1 8.2 6.3 6 0 0 6 6 6 4 EGF-like domain Laminin_EGF PF00053.24 KDO21447.1 - 0.0096 16.1 37.7 0.19 11.9 6.7 3.8 3 0 0 3 3 3 2 Laminin EGF domain EGF PF00008.27 KDO21447.1 - 0.019 15.3 4.6 0.019 15.3 4.6 5.1 5 0 0 5 5 5 0 EGF-like domain hEGF PF12661.7 KDO21447.1 - 0.044 14.4 3.9 0.044 14.4 3.9 5.6 5 0 0 5 5 5 0 Human growth factor-like EGF Herpes_pp85 PF04637.12 KDO21448.1 - 1.3 7.4 3.3 1.6 7.1 3.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FUN14 PF04930.15 KDO21449.1 - 0.00026 21.3 0.4 0.0016 18.8 0.4 2.2 1 1 0 1 1 1 1 FUN14 family Tyrosinase PF00264.20 KDO21450.1 - 1.5e-23 84.2 0.1 4.1e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Ldh_1_C PF02866.18 KDO21451.1 - 5.7e-52 176.0 0.0 8.3e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KDO21451.1 - 1.1e-28 100.1 0.1 1.9e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 KDO21451.1 - 0.06 12.9 0.6 0.19 11.3 0.4 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase DEP PF00610.21 KDO21453.1 - 0.015 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3477 PF11963.8 KDO21453.1 - 0.062 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) DNA_pol_B PF00136.21 KDO21454.1 - 7.9e-110 367.7 0.0 1.2e-109 367.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KDO21454.1 - 8.8e-45 152.7 1.0 2e-44 151.5 1.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KDO21454.1 - 1.9e-31 109.5 0.0 3.3e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KDO21454.1 - 1.4e-13 50.7 8.1 8.4e-13 48.2 8.1 2.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal CHASE3 PF05227.13 KDO21454.1 - 1.5 8.7 6.1 0.22 11.4 0.1 2.5 3 0 0 3 3 3 0 CHASE3 domain Rad51 PF08423.11 KDO21455.1 - 7.2e-122 405.5 0.1 9.8e-122 405.1 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KDO21455.1 - 6.4e-11 42.2 0.1 1e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KDO21455.1 - 9.1e-10 38.4 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KDO21455.1 - 7.9e-09 36.0 4.4 1.8e-08 34.8 1.1 3.1 3 1 0 3 3 3 1 Helix-hairpin-helix domain ATPase PF06745.13 KDO21455.1 - 4e-07 29.6 0.0 8.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 KDO21455.1 - 9.1e-05 21.9 0.1 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PhageP22-tail PF09251.10 KDO21455.1 - 0.034 12.5 0.2 0.053 11.9 0.2 1.2 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike AAA_28 PF13521.6 KDO21455.1 - 0.036 14.3 0.7 0.12 12.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain HHH_2 PF12826.7 KDO21455.1 - 0.094 12.8 0.1 0.36 11.0 0.1 2.0 1 1 1 2 2 2 0 Helix-hairpin-helix motif HHH_3 PF12836.7 KDO21455.1 - 0.12 12.6 0.2 2 8.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 KDO21455.1 - 0.14 12.0 0.0 1 9.2 0.0 2.4 2 1 1 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain RecA PF00154.21 KDO21456.1 - 4.8e-137 455.7 2.7 5.9e-137 455.4 2.7 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 KDO21456.1 - 1.3e-12 47.6 0.8 2.5e-11 43.3 0.8 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KDO21456.1 - 6.9e-09 35.4 0.5 6.4e-07 28.9 0.0 2.7 1 1 1 2 2 2 1 KaiC ATPase_2 PF01637.18 KDO21456.1 - 3.8e-05 23.7 0.0 8.7e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KDO21456.1 - 6e-05 22.9 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO21456.1 - 0.00062 19.4 0.5 0.0096 15.5 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KDO21456.1 - 0.004 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO21456.1 - 0.0041 17.5 0.1 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CobU PF02283.16 KDO21456.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TK PF00265.18 KDO21456.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase DnaB_C PF03796.15 KDO21456.1 - 0.039 13.3 0.2 0.46 9.8 0.0 2.1 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KDO21456.1 - 0.05 13.6 0.0 0.76 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_35 PF14516.6 KDO21456.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain GRAM PF02893.20 KDO21457.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 GRAM domain bPH_3 PF14470.6 KDO21457.1 - 0.044 14.1 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.8 KDO21457.1 - 0.081 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 PK PF00224.21 KDO21458.1 - 6e-129 429.9 0.0 7.6e-129 429.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KDO21458.1 - 2.4e-29 101.9 1.8 5.7e-29 100.7 1.8 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KDO21458.1 - 0.0015 17.7 1.4 0.0028 16.8 0.2 2.0 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Defensin_1 PF00323.19 KDO21459.1 - 7.3 7.3 15.9 0.47 11.1 0.6 3.2 3 0 0 3 3 3 0 Mammalian defensin tRNA-synt_2b PF00587.25 KDO21460.1 - 3.4e-35 121.6 0.0 4.7e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KDO21460.1 - 4e-05 23.7 0.0 7.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Fib_alpha PF08702.10 KDO21461.1 - 0.0017 18.6 4.8 0.0017 18.6 4.8 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Macoilin PF09726.9 KDO21461.1 - 0.0066 15.1 3.9 0.0089 14.6 3.9 1.1 1 0 0 1 1 1 1 Macoilin family BLOC1_2 PF10046.9 KDO21461.1 - 1.5 9.1 12.0 1.9 8.8 4.2 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 C2 PF00168.30 KDO21462.1 - 0.017 15.4 0.0 0.051 13.9 0.0 1.7 2 0 0 2 2 2 0 C2 domain Sulfate_transp PF00916.20 KDO21464.1 - 6.3e-21 74.6 27.3 1e-20 73.8 27.3 1.4 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KDO21464.1 - 3.1e-09 36.8 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KDO21464.1 - 8e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain Anoctamin PF04547.12 KDO21465.1 - 3e-67 227.4 6.3 4.2e-67 226.9 6.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 KDO21465.1 - 4.7e-14 52.5 0.1 9.7e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain HTH_18 PF12833.7 KDO21465.1 - 0.11 12.8 0.0 0.46 10.8 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain EF-hand_6 PF13405.6 KDO21468.1 - 2.2e-11 42.7 1.0 2.2e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KDO21468.1 - 2.8e-11 43.7 0.1 3.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO21468.1 - 5.2e-10 38.1 2.4 5.3e-05 22.5 0.2 2.8 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 KDO21468.1 - 8e-08 31.4 1.0 0.00075 18.9 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO21468.1 - 9.1e-06 25.4 0.1 0.071 13.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 KDO21468.1 - 0.02 14.9 0.0 0.68 9.8 0.0 2.0 1 1 1 2 2 2 0 Caleosin related protein zf-CCHC_5 PF14787.6 KDO21468.1 - 0.09 12.5 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Abhydrolase_9_N PF15420.6 KDO21469.1 - 0.0065 16.5 0.7 0.064 13.3 0.2 2.0 1 1 1 2 2 2 2 Alpha/beta-hydrolase family N-terminus DUF1700 PF08006.11 KDO21469.1 - 1.9 8.0 13.4 2.3 7.7 6.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) LRR_9 PF14580.6 KDO21470.1 - 4e-66 221.8 1.2 6e-66 221.2 1.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat SAP PF02037.27 KDO21470.1 - 2.8e-13 49.3 1.8 6e-13 48.2 0.9 2.1 2 0 0 2 2 2 1 SAP domain LRR_4 PF12799.7 KDO21470.1 - 1.1e-06 28.8 7.2 0.083 13.4 2.2 3.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21470.1 - 0.00056 19.6 5.4 0.011 15.5 3.9 2.8 2 1 1 3 3 3 2 Leucine rich repeat HeH PF12949.7 KDO21470.1 - 0.076 12.7 0.1 0.23 11.2 0.1 1.9 1 1 0 1 1 1 0 HeH/LEM domain DUF2457 PF10446.9 KDO21470.1 - 0.22 10.6 7.6 0.3 10.2 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ndc1_Nup PF09531.10 KDO21470.1 - 2.1 7.0 5.1 2.5 6.7 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_16 PF10294.9 KDO21471.1 - 3.1e-15 56.3 0.0 4.1e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KDO21471.1 - 0.0044 16.9 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Beta_helix PF13229.6 KDO21472.1 - 2.6e-19 69.6 7.4 7e-09 35.7 0.1 2.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KDO21472.1 - 8.3e-13 48.2 0.3 8.6e-09 35.0 0.4 1.9 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) TRM PF02005.16 KDO21473.1 - 3.9e-55 187.5 0.0 5.2e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KDO21473.1 - 1.3e-05 25.0 0.0 3.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KDO21473.1 - 0.009 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KDO21473.1 - 0.0091 15.8 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KDO21473.1 - 0.015 16.0 0.1 0.037 14.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KDO21473.1 - 0.019 14.3 0.9 0.019 14.3 0.9 1.6 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KDO21473.1 - 0.061 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 KDO21473.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Lar_restr_allev PF14354.6 KDO21474.1 - 0.033 14.6 0.7 0.054 13.9 0.7 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar cNMP_binding PF00027.29 KDO21476.1 - 3.2e-13 49.5 0.1 5.7e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO21476.1 - 8.4e-07 28.5 3.3 1.6e-06 27.6 2.9 1.7 1 1 0 1 1 1 1 Ion transport protein TRIC PF05197.13 KDO21476.1 - 0.12 11.9 1.7 0.28 10.8 1.7 1.5 1 0 0 1 1 1 0 TRIC channel DUF2281 PF10047.9 KDO21476.1 - 0.16 12.7 0.0 0.36 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) GREB1 PF15782.5 KDO21477.1 - 3.7 4.5 9.3 4.4 4.3 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ERM PF00769.19 KDO21477.1 - 8.4 6.1 34.5 51 3.6 34.4 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family His_Phos_1 PF00300.22 KDO21478.1 - 5e-28 98.1 0.0 2.9e-13 50.0 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) UPF1_Zn_bind PF09416.10 KDO21479.1 - 1e-73 246.3 3.7 4.8e-73 244.2 1.7 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KDO21479.1 - 5.2e-60 202.5 0.0 8.3e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KDO21479.1 - 3.3e-50 171.3 3.1 1.5e-30 106.8 0.1 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KDO21479.1 - 5e-26 90.8 0.0 1.4e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KDO21479.1 - 8.3e-14 51.8 4.7 1.4e-13 51.0 2.6 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KDO21479.1 - 6.7e-12 46.0 0.4 1.6e-11 44.8 0.4 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KDO21479.1 - 3.5e-06 26.8 0.6 0.00071 19.2 0.3 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KDO21479.1 - 4e-05 23.6 0.3 0.00013 21.8 0.3 2.0 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 KDO21479.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KDO21479.1 - 0.00026 20.4 4.2 0.0015 17.9 0.3 3.2 3 1 1 4 4 4 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KDO21479.1 - 0.00084 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 KaiC Viral_helicase1 PF01443.18 KDO21479.1 - 0.0034 17.2 0.1 1 9.1 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KDO21479.1 - 0.0037 17.5 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KDO21479.1 - 0.0092 15.4 0.2 0.026 14.0 0.1 1.7 2 0 0 2 2 2 1 PhoH-like protein PIF1 PF05970.14 KDO21479.1 - 0.015 14.5 0.3 2.7 7.1 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.6 KDO21479.1 - 0.019 14.6 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO21479.1 - 0.053 13.9 0.6 0.14 12.5 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 KDO21479.1 - 0.063 13.0 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.12 KDO21479.1 - 0.065 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_5 PF07728.14 KDO21479.1 - 0.079 13.0 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KDO21479.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pept_tRNA_hydro PF01195.19 KDO21482.1 - 5e-41 140.5 0.0 7.4e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF1409 PF07197.12 KDO21482.1 - 0.2 11.6 0.2 1.3 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DAHP_synth_1 PF00793.20 KDO21483.1 - 4.5e-54 183.2 0.0 6.1e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family cNMP_binding PF00027.29 KDO21484.1 - 3.1e-18 65.6 0.1 3.6e-09 36.6 0.1 4.6 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO21485.1 - 1.7e-88 296.2 0.0 2.7e-47 161.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO21485.1 - 6e-87 291.4 0.0 1.5e-48 165.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KDO21485.1 - 2.5e-05 23.3 0.0 0.00054 18.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO21485.1 - 0.0001 21.7 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO21485.1 - 0.003 17.5 0.0 2.5 8.0 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO21485.1 - 0.051 12.5 0.0 0.37 9.7 0.0 2.2 2 1 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KDO21485.1 - 0.058 12.7 0.0 1.1 8.5 0.0 2.3 2 1 0 2 2 2 0 Kinase-like PsbJ PF01788.17 KDO21485.1 - 0.22 11.4 2.8 0.53 10.2 2.8 1.6 1 0 0 1 1 1 0 PsbJ LRR_8 PF13855.6 KDO21486.1 - 2.4e-43 145.7 66.3 1.7e-10 40.5 1.8 9.0 5 2 6 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KDO21486.1 - 1.7e-42 142.7 44.0 6e-06 26.5 0.2 11.2 8 3 4 12 12 12 9 Leucine Rich repeats (2 copies) WW PF00397.26 KDO21486.1 - 3.9e-25 87.6 16.3 1.6e-10 40.9 2.2 3.7 3 0 0 3 3 3 3 WW domain LRR_1 PF00560.33 KDO21486.1 - 2.6e-07 30.3 31.6 3.7 8.5 0.1 15.0 18 0 0 18 18 16 1 Leucine Rich Repeat TPR_2 PF07719.17 KDO21486.1 - 4.3e-07 29.5 1.1 0.099 12.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO21486.1 - 4.5e-07 29.4 0.0 0.0084 15.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat IQ PF00612.27 KDO21486.1 - 5.2e-06 25.8 5.5 0.04 13.7 0.1 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_9 PF14580.6 KDO21486.1 - 1.9e-05 24.2 17.5 0.018 14.5 0.7 4.5 2 1 3 5 5 5 4 Leucine-rich repeat TPR_11 PF13414.6 KDO21486.1 - 0.00031 20.4 0.5 0.12 12.0 0.1 3.4 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.6 KDO21486.1 - 0.0021 18.7 1.7 0.0021 18.7 1.7 6.1 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO21486.1 - 0.0066 17.1 17.3 0.031 14.9 1.7 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO21486.1 - 0.075 13.7 12.1 0.2 12.4 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat LRR_6 PF13516.6 KDO21486.1 - 0.12 12.5 57.3 3.9 7.8 0.5 13.4 15 0 0 15 15 14 0 Leucine Rich repeat TPR_10 PF13374.6 KDO21486.1 - 3.3 7.7 7.2 26 4.9 0.3 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Big_3_4 PF13754.6 KDO21488.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function CENP-F_leu_zip PF10473.9 KDO21491.1 - 0.014 15.4 4.9 0.014 15.4 4.9 4.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KDO21491.1 - 0.099 13.2 41.9 0.035 14.6 10.2 3.8 2 1 1 3 3 3 0 Apg6 coiled-coil region Enkurin PF13864.6 KDO21491.1 - 3.8 8.0 25.3 0.033 14.6 3.6 3.9 2 1 0 3 3 3 0 Calmodulin-binding Rap1_C PF11626.8 KDO21492.1 - 0.017 15.2 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EamA PF00892.20 KDO21493.1 - 9.3e-07 29.1 14.4 9.3e-07 29.1 14.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO21493.1 - 0.081 12.3 14.4 0.14 11.5 14.4 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family MFS_1 PF07690.16 KDO21494.1 - 0.038 12.9 1.0 0.058 12.3 1.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Methyltransf_25 PF13649.6 KDO21496.1 - 0.12 13.1 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FlaC_arch PF05377.11 KDO21497.1 - 0.018 15.4 0.1 0.051 14.0 0.1 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Mistic PF11458.8 KDO21497.1 - 0.031 14.2 0.0 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Membrane-integrating protein Mistic Med2 PF11214.8 KDO21497.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 RmuC PF02646.16 KDO21497.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 RmuC family HTH_Tnp_Tc5 PF03221.16 KDO21498.1 - 1.7e-10 40.8 0.0 3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KDO21498.1 - 1.2e-07 31.3 0.6 1.9e-07 30.6 0.6 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KDO21498.1 - 7.1e-06 25.7 0.2 2.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KDO21498.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KDO21498.1 - 0.014 15.5 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 KDO21498.1 - 0.018 15.1 0.0 0.41 10.7 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix HTH_29 PF13551.6 KDO21498.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix SRC-1 PF08832.10 KDO21498.1 - 0.071 14.2 0.2 0.2 12.7 0.2 1.7 1 0 0 1 1 1 0 Steroid receptor coactivator MerR-DNA-bind PF09278.11 KDO21498.1 - 2.2 8.9 5.1 0.83 10.2 0.2 2.9 3 1 0 3 3 3 0 MerR, DNA binding GAS PF13851.6 KDO21499.1 - 2.1e-69 232.9 22.5 2.1e-69 232.9 22.5 3.2 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding PET117 PF15786.5 KDO21499.1 - 0.00068 19.8 3.4 0.00068 19.8 3.4 5.0 4 2 0 4 4 4 1 PET assembly of cytochrome c oxidase, mitochondrial TEX12 PF15219.6 KDO21499.1 - 0.11 12.9 3.2 0.14 12.5 0.8 2.5 2 0 0 2 2 2 0 Testis-expressed 12 ARL2_Bind_BART PF11527.8 KDO21500.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART WW PF00397.26 KDO21500.1 - 1.3e-05 25.2 1.5 2.3e-05 24.4 1.5 1.4 1 0 0 1 1 1 1 WW domain Hydin_ADK PF17213.3 KDO21500.1 - 0.13 12.6 6.1 3.8 7.7 0.5 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Vps39_2 PF10367.9 KDO21500.1 - 0.25 11.8 1.4 0.85 10.1 1.4 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF3435 PF11917.8 KDO21500.1 - 2.8 6.8 12.5 4.5 6.1 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Ank_2 PF12796.7 KDO21503.1 - 2e-13 50.7 3.7 2.6e-09 37.5 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21503.1 - 6.6e-12 45.7 0.6 2.3e-05 24.9 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21503.1 - 1.3e-11 43.6 1.6 0.00036 20.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO21503.1 - 1.7e-09 37.7 4.8 0.0026 18.2 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KDO21503.1 - 2.3e-08 34.1 1.4 1.2e-07 31.8 0.3 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 KDO21505.1 - 1.9e-34 117.9 13.0 9.5e-12 45.2 0.3 5.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO21505.1 - 6.1e-33 109.9 14.4 1.7e-06 27.1 0.0 8.0 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.6 KDO21505.1 - 2.6e-31 107.2 15.2 5.2e-07 29.4 0.8 7.6 4 3 3 7 7 7 6 EF-hand domain pair EF-hand_6 PF13405.6 KDO21505.1 - 3.6e-29 98.1 16.8 5.2e-06 26.0 0.1 8.5 8 0 0 8 8 8 6 EF-hand domain Metallophos PF00149.28 KDO21505.1 - 3.8e-27 96.1 0.1 6.5e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_5 PF13202.6 KDO21505.1 - 3.3e-23 80.1 13.2 0.00014 21.2 0.2 6.8 6 0 0 6 6 6 5 EF hand EF-hand_11 PF08976.11 KDO21505.1 - 7.1e-12 46.1 1.0 0.0041 18.0 0.0 4.3 2 2 2 4 4 4 3 EF-hand domain PPP5 PF08321.12 KDO21505.1 - 6.5e-10 39.2 0.0 1.8e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region CAP_GLY PF01302.25 KDO21505.1 - 1.3e-09 37.9 0.5 5.8e-09 35.8 0.1 2.3 2 0 0 2 2 2 1 CAP-Gly domain SPARC_Ca_bdg PF10591.9 KDO21505.1 - 7.2e-07 29.5 3.1 1.4 9.3 0.0 4.5 5 0 0 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO21505.1 - 1.9e-06 27.7 7.6 0.00094 19.1 0.6 5.1 3 2 2 5 5 5 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KDO21505.1 - 0.00011 22.4 0.4 1.5 9.2 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain Caleosin PF05042.13 KDO21505.1 - 0.007 16.3 1.3 0.37 10.7 0.0 3.7 4 0 0 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 KDO21505.1 - 0.0098 14.5 0.1 1.9 6.9 0.0 2.6 2 1 1 3 3 3 2 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 KDO21505.1 - 0.09 12.6 1.5 0.49 10.3 0.2 2.9 3 0 0 3 3 3 0 EF hand Peptidase_C69 PF03577.15 KDO21506.1 - 1.5e-42 146.0 0.0 4e-42 144.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C69 Clathrin PF00637.20 KDO21507.1 - 9.2e-111 366.0 4.4 5.7e-32 110.6 0.6 6.2 6 0 0 6 6 6 5 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KDO21507.1 - 1.5e-25 88.9 0.1 4.2e-25 87.5 0.1 1.8 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 KDO21507.1 - 9e-19 66.8 0.4 6.1e-08 32.6 0.0 5.8 6 0 0 6 6 6 3 Clathrin propeller repeat Clathrin-link PF09268.10 KDO21507.1 - 8.8e-06 25.0 0.0 2.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 KDO21507.1 - 0.00075 20.1 1.7 63 4.8 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO21507.1 - 0.02 14.9 0.6 7.1 6.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO21507.1 - 0.042 14.0 0.2 13 6.2 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO21507.1 - 0.094 12.6 0.1 35 4.5 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO21508.1 - 0.0008 19.7 16.7 0.0022 18.2 7.1 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat HTH_Tnp_Mu_2 PF09039.11 KDO21508.1 - 0.049 13.7 2.2 0.92 9.6 0.1 3.3 3 1 0 4 4 4 0 Mu DNA binding, I gamma subdomain RNA_pol_Rpb6 PF01192.22 KDO21508.1 - 0.052 13.5 1.0 0.49 10.4 1.0 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb6 TPR_2 PF07719.17 KDO21508.1 - 0.26 11.5 17.0 1.4 9.3 0.7 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO21508.1 - 0.35 10.8 13.5 3.7 7.5 0.9 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO21508.1 - 0.36 10.7 8.4 0.42 10.5 0.3 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 KDO21509.1 - 2.1e-34 114.5 9.8 1.8e-06 27.1 0.1 6.7 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 KDO21509.1 - 5.1e-32 110.1 14.7 7.5e-11 42.3 0.6 3.9 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO21509.1 - 2.1e-29 98.9 17.8 1.2e-06 28.0 0.2 6.9 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 KDO21509.1 - 3e-28 97.4 13.3 5.4e-07 29.4 0.8 6.3 3 3 3 6 6 6 5 EF-hand domain pair Metallophos PF00149.28 KDO21509.1 - 1.2e-27 97.8 0.0 2.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_5 PF13202.6 KDO21509.1 - 5e-22 76.4 12.1 8e-05 22.0 0.2 6.6 6 0 0 6 6 6 5 EF hand EF-hand_11 PF08976.11 KDO21509.1 - 1.6e-15 57.9 0.5 6.3e-05 23.8 0.0 4.4 2 2 2 4 4 4 3 EF-hand domain CAP_GLY PF01302.25 KDO21509.1 - 1.3e-11 44.3 0.0 3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_4 PF12763.7 KDO21509.1 - 7.1e-10 38.8 4.5 3.8e-05 23.6 0.2 4.4 3 2 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KDO21509.1 - 3.2e-06 27.4 0.9 0.44 10.9 0.0 3.8 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO21509.1 - 0.0008 19.7 1.3 3.6 8.0 0.1 3.7 3 1 0 3 3 3 1 EF-hand domain PPP5 PF08321.12 KDO21509.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 PPP5 TPR repeat region EF-hand_10 PF14788.6 KDO21509.1 - 0.14 12.1 4.4 0.51 10.2 0.2 3.3 4 0 0 4 4 4 0 EF hand IQ PF00612.27 KDO21509.1 - 0.17 11.7 3.0 0.53 10.2 3.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Caleosin PF05042.13 KDO21509.1 - 0.32 10.9 1.8 9.2 6.2 0.0 3.9 4 1 0 4 4 4 0 Caleosin related protein CoA_binding PF02629.19 KDO21510.1 - 3.2e-32 111.1 3.8 4.2e-32 110.7 1.1 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KDO21510.1 - 3.5e-24 85.4 0.1 5.7e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KDO21510.1 - 6.8e-10 38.9 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KDO21510.1 - 6.3e-05 23.5 0.1 0.00027 21.4 0.1 2.1 3 0 0 3 3 3 1 CoA binding domain IBB PF01749.20 KDO21511.1 - 4.8 7.7 10.1 0.95 9.9 5.8 2.0 2 1 0 2 2 2 0 Importin beta binding domain CCT PF06203.14 KDO21514.1 - 5.5e-13 48.7 4.2 1.1e-12 47.8 4.2 1.5 1 0 0 1 1 1 1 CCT motif ABC_membrane PF00664.23 KDO21515.1 - 3.6e-68 230.2 13.3 2e-38 132.6 3.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO21515.1 - 2.4e-47 160.9 0.0 1.5e-27 96.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO21515.1 - 1.2e-09 38.0 0.4 0.19 11.2 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO21515.1 - 1.5e-06 27.9 0.9 0.028 14.2 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO21515.1 - 5.1e-06 27.0 0.7 0.037 14.4 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO21515.1 - 6.3e-06 26.3 0.8 0.073 13.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO21515.1 - 0.00013 21.9 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KDO21515.1 - 0.00019 21.4 0.2 0.15 11.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO21515.1 - 0.00053 20.3 0.5 0.19 12.0 0.1 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 KDO21515.1 - 0.0023 18.0 5.1 0.076 13.1 0.5 2.4 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KDO21515.1 - 0.0026 18.3 0.1 0.44 11.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KDO21515.1 - 0.0073 15.4 0.8 1.1 8.3 0.3 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KDO21515.1 - 0.015 14.9 1.0 3.7 7.1 0.6 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO21515.1 - 0.023 14.8 2.2 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 KDO21515.1 - 0.028 14.2 0.3 3 7.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 KDO21515.1 - 0.036 13.3 0.6 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KDO21515.1 - 0.051 13.2 2.2 0.51 9.9 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KDO21515.1 - 0.051 13.1 0.3 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KDO21515.1 - 0.062 13.5 3.0 0.44 10.7 0.6 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO21515.1 - 0.072 12.8 2.7 2.1 8.0 0.4 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KDO21515.1 - 0.12 12.1 1.6 4.5 7.0 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KDO21515.1 - 0.16 11.9 2.3 2.4 8.1 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KDO21515.1 - 0.22 12.1 2.4 15 6.1 0.3 2.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KDO21515.1 - 0.22 10.5 1.6 0.51 9.3 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KDO21515.1 - 0.24 11.6 0.6 10 6.4 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KDO21515.1 - 0.27 10.6 2.0 16 4.8 0.5 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_membrane PF00664.23 KDO21516.1 - 3.1e-50 171.3 25.7 7.7e-27 94.6 14.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO21516.1 - 2.5e-45 154.4 0.0 1.9e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO21516.1 - 2.5e-09 36.9 3.6 0.069 12.6 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO21516.1 - 9.7e-06 26.1 0.1 0.056 13.8 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO21516.1 - 1.7e-05 24.9 0.6 0.063 13.4 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO21516.1 - 0.001 19.0 0.4 0.63 9.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 KDO21516.1 - 0.0015 18.5 1.5 0.059 13.3 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.6 KDO21516.1 - 0.0035 17.1 2.4 0.47 10.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KDO21516.1 - 0.0042 16.8 0.0 1.8 8.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO21516.1 - 0.0055 15.9 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KDO21516.1 - 0.0058 16.9 2.5 0.91 9.8 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO21516.1 - 0.0059 16.4 4.4 0.19 11.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KDO21516.1 - 0.0069 15.5 0.0 0.55 9.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 KDO21516.1 - 0.0086 16.6 0.1 3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO21516.1 - 0.009 16.2 1.2 0.42 10.8 0.1 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 KDO21516.1 - 0.0094 16.0 2.6 1.5 8.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KDO21516.1 - 0.011 16.3 0.2 2 8.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO21516.1 - 0.018 15.3 0.3 7.7 6.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KDO21516.1 - 0.024 14.5 0.0 5.2 6.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KDO21516.1 - 0.024 15.1 0.1 3.3 8.1 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KDO21516.1 - 0.027 14.2 0.6 5.3 6.7 0.1 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KDO21516.1 - 0.035 13.5 0.6 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KDO21516.1 - 0.036 13.8 1.6 2 8.2 0.3 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KDO21516.1 - 0.072 12.6 0.8 14 5.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KDO21516.1 - 0.077 13.0 0.2 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KDO21516.1 - 0.088 12.9 4.7 0.3 11.1 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KDO21516.1 - 0.097 13.1 0.3 40 4.7 0.0 3.6 4 0 0 4 4 3 0 RNA helicase AAA_25 PF13481.6 KDO21516.1 - 0.23 11.0 1.6 13 5.3 0.4 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KDO21516.1 - 0.28 10.3 2.2 2.1 7.5 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 KDO21516.1 - 1.4 8.7 3.4 8.7 6.1 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 KDO21516.1 - 2.1 7.9 7.5 1.4 8.5 0.1 3.1 3 1 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Myb_DNA-binding PF00249.31 KDO21517.1 - 7.7e-09 35.6 0.1 1.3e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO21517.1 - 0.0034 17.6 0.2 0.0062 16.8 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_2 PF07719.17 KDO21518.1 - 5.2e-12 44.9 5.6 0.0016 18.4 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO21518.1 - 9.3e-10 38.0 10.9 2.4e-05 23.9 0.0 4.7 3 1 2 5 5 5 3 TPR repeat TPR_1 PF00515.28 KDO21518.1 - 3.5e-07 29.8 2.7 0.034 14.0 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO21518.1 - 1.2e-05 25.3 3.4 1 9.9 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO21518.1 - 1.9e-05 24.5 0.0 0.62 10.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO21518.1 - 1.9e-05 25.2 12.6 0.057 14.1 2.0 4.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO21518.1 - 3.2e-05 24.1 17.1 3.5e-05 24.0 0.7 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO21518.1 - 0.00012 22.6 12.6 0.094 13.6 0.2 5.8 2 1 4 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO21518.1 - 0.029 14.2 13.5 0.11 12.4 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO21518.1 - 0.11 13.2 1.1 41 5.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO21518.1 - 0.12 12.5 7.5 4 7.7 1.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO21518.1 - 0.15 12.6 16.3 0.13 12.8 0.8 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO21518.1 - 0.55 10.4 9.3 19 5.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO21518.1 - 1.4 9.8 13.1 27 5.8 0.3 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 KDO21519.1 - 3.2e-52 176.7 0.0 2e-25 89.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO21519.1 - 9.1e-51 173.0 46.5 8.8e-28 97.4 17.3 3.2 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO21519.1 - 3.7e-19 69.7 0.5 2.3e-06 27.6 0.1 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO21519.1 - 4.5e-05 23.3 0.1 0.41 10.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KDO21519.1 - 0.00018 22.1 0.9 0.054 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO21519.1 - 0.00028 20.4 0.0 1.3 8.4 0.0 3.4 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO21519.1 - 0.00045 20.2 0.2 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 KDO21519.1 - 0.0011 18.6 0.8 0.51 9.9 0.1 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KDO21519.1 - 0.0015 18.2 1.6 0.24 11.2 0.1 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane PF01061.24 KDO21519.1 - 0.0078 15.7 39.7 0.031 13.7 18.4 3.9 4 0 0 4 4 4 1 ABC-2 type transporter AAA_22 PF13401.6 KDO21519.1 - 0.011 16.0 0.4 3.7 7.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KDO21519.1 - 0.025 14.8 0.3 3.8 7.8 0.0 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KDO21519.1 - 0.034 13.8 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 KDO21519.1 - 0.047 14.4 0.0 1.8 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KDO21519.1 - 0.094 13.1 0.1 25 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain MukB PF04310.12 KDO21519.1 - 0.12 12.2 2.0 0.91 9.3 0.2 2.4 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.23 KDO21519.1 - 0.15 12.1 0.3 23 5.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KDO21519.1 - 1.1 9.5 2.8 19 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Hist_deacetyl PF00850.19 KDO21520.1 - 9e-73 245.4 0.0 1.1e-72 245.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain GCP_C_terminal PF04130.13 KDO21521.1 - 6.7e-31 107.9 12.9 1.2e-30 107.1 12.9 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KDO21521.1 - 4.5e-05 23.2 5.6 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal LIP1 PF15904.5 KDO21521.1 - 0.085 13.2 0.2 0.32 11.4 0.2 2.0 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 DUF2807 PF10988.8 KDO21522.1 - 1.1e-12 48.1 9.9 1.1e-07 31.8 5.6 3.3 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain Cation_efflux PF01545.21 KDO21523.1 - 7e-31 107.5 8.9 8.5e-31 107.2 8.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KDO21523.1 - 3.1e-09 36.8 0.5 6.1e-09 35.9 0.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2749 PF10907.8 KDO21523.1 - 9.4 6.5 8.7 0.77 10.0 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Dimer_Tnp_hAT PF05699.14 KDO21524.1 - 9.6e-06 25.3 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TACC_C PF05010.14 KDO21524.1 - 0.0052 16.6 0.3 0.0062 16.3 0.3 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DASH_Dad4 PF08650.10 KDO21524.1 - 0.072 13.1 0.9 4.2 7.4 0.1 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad4 BTB_2 PF02214.22 KDO21525.1 - 0.00011 22.5 0.2 0.61 10.5 0.0 2.9 1 1 1 2 2 2 2 BTB/POZ domain DUF1353 PF07087.11 KDO21525.1 - 0.089 12.5 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) BTB_2 PF02214.22 KDO21526.1 - 2.8e-13 50.0 0.0 7.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KDO21526.1 - 2.9e-05 24.1 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KDO21526.1 - 0.0047 17.1 0.0 0.0086 16.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Atg14 PF10186.9 KDO21526.1 - 0.02 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KDO21526.1 - 0.071 12.0 1.2 0.11 11.3 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_membrane PF00664.23 KDO21527.1 - 1.6e-43 149.3 29.2 5.6e-28 98.4 7.3 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO21527.1 - 1.7e-40 138.7 0.0 2.1e-25 89.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO21527.1 - 4e-12 46.1 2.2 0.0075 15.7 0.0 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO21527.1 - 2.4e-06 28.1 0.7 0.019 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO21527.1 - 2.4e-06 27.2 0.1 0.012 15.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KDO21527.1 - 4.8e-05 23.5 1.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KDO21527.1 - 5e-05 23.4 0.3 0.4 10.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KDO21527.1 - 0.0001 22.3 0.3 0.85 9.4 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO21527.1 - 0.00022 21.5 0.2 0.51 10.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO21527.1 - 0.00066 19.6 0.1 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KDO21527.1 - 0.00069 19.4 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KDO21527.1 - 0.0011 18.4 0.2 0.73 9.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 KDO21527.1 - 0.0024 18.0 0.7 0.038 14.1 0.2 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain DUF815 PF05673.13 KDO21527.1 - 0.0027 16.9 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KDO21527.1 - 0.0033 17.3 0.4 1.8 8.3 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KDO21527.1 - 0.0035 17.9 0.2 1.5 9.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO21527.1 - 0.0036 17.5 0.0 0.71 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KDO21527.1 - 0.0072 15.4 0.2 3.2 6.7 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 KDO21527.1 - 0.0077 16.7 0.0 2.1 8.8 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO21527.1 - 0.011 15.3 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KDO21527.1 - 0.014 15.1 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO21527.1 - 0.023 14.0 0.2 0.34 10.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KDO21527.1 - 0.024 14.4 0.0 3 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KDO21527.1 - 0.033 13.8 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KDO21527.1 - 0.074 13.6 0.1 16 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KDO21527.1 - 0.12 11.6 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 KDO21527.1 - 0.12 12.7 0.0 34 4.9 0.0 2.9 3 0 0 3 3 3 0 RNA helicase Roc PF08477.13 KDO21527.1 - 0.15 12.3 0.1 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KDO21527.1 - 0.15 11.1 1.5 0.47 9.5 0.2 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MeaB PF03308.16 KDO21527.1 - 0.16 10.9 1.5 0.66 8.9 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KDO21527.1 - 0.18 11.2 0.0 9.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Adeno_IVa2 PF02456.15 KDO21527.1 - 0.22 10.3 0.1 1 8.1 0.1 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 KDO21527.1 - 0.33 10.6 1.4 4.9 6.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 KDO21529.1 - 1.1e-41 143.4 29.2 5e-27 95.3 6.6 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO21529.1 - 2.1e-40 138.4 0.0 1.4e-25 90.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO21529.1 - 7.3e-12 45.2 2.8 0.008 15.6 0.2 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO21529.1 - 2.4e-06 27.2 0.1 0.012 15.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO21529.1 - 5.4e-06 26.9 0.5 0.019 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KDO21529.1 - 4e-05 23.7 0.8 0.046 13.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KDO21529.1 - 5.1e-05 23.3 0.3 0.43 10.7 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KDO21529.1 - 9.3e-05 22.4 0.2 0.85 9.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO21529.1 - 0.00024 21.4 0.3 0.5 10.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO21529.1 - 0.00065 19.6 0.1 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KDO21529.1 - 0.0012 18.6 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KDO21529.1 - 0.0014 18.0 0.4 0.73 9.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 KDO21529.1 - 0.0023 18.1 0.7 0.038 14.1 0.2 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain ATP_bind_1 PF03029.17 KDO21529.1 - 0.0031 17.3 0.4 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KDO21529.1 - 0.0035 17.9 0.2 1.5 9.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO21529.1 - 0.0039 16.4 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 KDO21529.1 - 0.0042 17.2 0.1 0.7 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO21529.1 - 0.0055 17.1 0.0 2.1 8.8 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KDO21529.1 - 0.0062 15.6 0.2 3.1 6.8 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KDO21529.1 - 0.011 15.2 0.1 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KDO21529.1 - 0.015 15.0 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO21529.1 - 0.022 14.0 0.2 0.34 10.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KDO21529.1 - 0.022 14.5 0.0 3 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KDO21529.1 - 0.033 13.8 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KDO21529.1 - 0.059 13.9 0.1 16 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO21529.1 - 0.11 12.8 0.0 34 4.9 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Septin PF00735.18 KDO21529.1 - 0.12 11.7 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin Roc PF08477.13 KDO21529.1 - 0.15 12.3 0.1 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KDO21529.1 - 0.15 11.0 1.7 0.66 8.9 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KDO21529.1 - 0.17 11.2 0.0 9.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IIGP PF05049.13 KDO21529.1 - 0.21 10.6 1.8 0.46 9.5 0.2 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 KDO21529.1 - 0.35 10.6 1.6 4.9 6.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain BTB_2 PF02214.22 KDO21530.1 - 1.4e-12 47.7 0.0 3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KDO21530.1 - 4.6e-05 23.5 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Atg14 PF10186.9 KDO21530.1 - 0.037 13.1 0.1 0.052 12.6 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UpxZ PF06603.11 KDO21530.1 - 0.053 13.8 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists BTB PF00651.31 KDO21530.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Spc7 PF08317.11 KDO21530.1 - 0.18 10.7 3.6 0.43 9.4 2.5 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-BED PF02892.15 KDO21531.1 - 0.00016 21.6 3.3 0.00043 20.2 3.6 1.7 1 1 1 2 2 2 1 BED zinc finger RICTOR_phospho PF14665.6 KDO21531.1 - 0.047 14.0 0.2 0.059 13.7 0.2 1.4 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site CENP-F_leu_zip PF10473.9 KDO21533.1 - 0.0085 16.1 4.3 0.0085 16.1 4.3 4.6 2 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Enkurin PF13864.6 KDO21533.1 - 0.025 15.0 3.6 0.025 15.0 3.6 4.0 2 1 2 4 4 4 0 Calmodulin-binding APG6_N PF17675.1 KDO21533.1 - 0.026 15.1 10.8 0.026 15.1 10.8 3.9 2 1 1 3 3 3 0 Apg6 coiled-coil region US30 PF17624.2 KDO21533.1 - 1.3 8.0 7.9 3.2 6.7 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function CortBP2 PF09727.9 KDO21533.1 - 2.2 8.2 41.0 0.11 12.4 10.6 3.2 2 1 1 3 3 3 0 Cortactin-binding protein-2 Golgin_A5 PF09787.9 KDO21533.1 - 5.5 6.3 42.0 1.6 8.1 2.8 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 Atg14 PF10186.9 KDO21533.1 - 7.3 5.6 37.7 1 8.3 14.0 3.3 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KDO21533.1 - 8.5 6.4 17.6 0.22 11.6 0.7 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF5446 PF17522.2 KDO21533.1 - 9 6.5 8.4 0.75 10.0 0.4 3.3 3 1 1 4 4 4 0 Family of unknown function (DUF5446) Rap1_C PF11626.8 KDO21534.1 - 0.21 11.7 0.2 0.44 10.7 0.2 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EamA PF00892.20 KDO21535.1 - 7.5e-07 29.4 14.3 7.5e-07 29.4 14.3 2.9 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 KDO21535.1 - 0.055 12.8 17.5 0.079 12.3 17.5 1.3 1 0 0 1 1 1 0 Triose-phosphate Transporter family PI3_PI4_kinase PF00454.27 KDO21536.1 - 1.3e-72 244.6 0.0 2.7e-72 243.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KDO21536.1 - 7.6e-58 196.4 4.7 1.2e-57 195.7 0.4 3.0 2 1 0 2 2 2 1 FAT domain DUF3385 PF11865.8 KDO21536.1 - 5.7e-39 133.6 0.0 1.5e-32 112.7 0.0 5.2 3 2 1 4 4 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KDO21536.1 - 2.4e-34 117.7 1.6 7.3e-34 116.1 0.3 2.7 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KDO21536.1 - 2e-18 65.9 0.6 4.6e-18 64.7 0.6 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KDO21536.1 - 8.5e-08 32.5 7.9 0.025 15.0 0.1 8.5 9 1 1 10 10 10 1 HEAT repeats HEAT_EZ PF13513.6 KDO21536.1 - 7.4e-07 29.5 19.0 0.071 13.6 0.0 9.8 11 0 0 11 11 10 2 HEAT-like repeat UME PF08064.13 KDO21536.1 - 1.7e-06 27.9 2.7 0.34 10.8 0.0 5.7 6 0 0 6 6 6 2 UME (NUC010) domain TPR_19 PF14559.6 KDO21536.1 - 1.9e-06 28.3 0.2 0.24 11.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat CLASP_N PF12348.8 KDO21536.1 - 0.00039 20.1 0.3 1.6 8.3 0.0 4.9 4 1 0 5 5 5 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 KDO21536.1 - 0.0005 20.6 0.0 0.57 10.8 0.0 4.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region TPR_14 PF13428.6 KDO21536.1 - 0.0011 19.5 2.7 1.5 9.8 0.0 5.7 5 0 0 5 5 3 1 Tetratricopeptide repeat Cnd1 PF12717.7 KDO21536.1 - 0.023 14.7 0.2 18 5.3 0.0 4.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TPR_9 PF13371.6 KDO21536.1 - 0.035 14.3 2.3 0.35 11.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 KDO21536.1 - 0.059 13.6 14.7 19 5.9 0.0 8.3 10 0 0 10 10 8 0 HEAT repeat Herpes_UL51 PF04540.13 KDO21536.1 - 0.12 12.2 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL51 protein Arm PF00514.23 KDO21536.1 - 0.17 12.0 0.5 22 5.3 0.1 4.3 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat YkuI_C PF10388.9 KDO21537.1 - 0.18 11.6 0.9 0.25 11.1 0.9 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain LPAM_1 PF08139.12 KDO21541.1 - 0.13 12.8 1.1 0.29 11.7 1.1 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_M14 PF00246.24 KDO21542.1 - 1.9e-12 47.6 0.0 5.7e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KDO21542.1 - 3.4e-08 33.8 0.0 7.1e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Arm PF00514.23 KDO21542.1 - 0.00067 19.6 6.7 0.12 12.4 0.1 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RNA_pol_3_Rpc31 PF11705.8 KDO21542.1 - 0.0036 17.6 4.0 0.0072 16.6 4.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Atx10homo_assoc PF09759.9 KDO21542.1 - 0.2 11.7 0.1 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain RXT2_N PF08595.11 KDO21542.1 - 0.42 10.6 3.0 0.9 9.6 3.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 KDO21542.1 - 1.9 6.6 9.1 0.23 9.6 4.7 1.6 2 0 0 2 2 2 0 Nop14-like family Ion_trans_2 PF07885.16 KDO21543.1 - 9.2e-09 35.2 5.6 2.6e-08 33.7 5.6 1.8 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KDO21543.1 - 0.11 11.7 8.2 0.03 13.5 4.3 2.1 2 1 0 2 2 2 0 Ion transport protein Pribosyltran PF00156.27 KDO21544.1 - 6.5e-13 48.5 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KDO21544.1 - 0.00017 21.1 0.5 0.00052 19.5 0.0 1.8 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Hist_deacetyl PF00850.19 KDO21546.1 - 1.8e-68 231.3 0.0 2.8e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank PF00023.30 KDO21546.1 - 5.8e-13 48.6 1.2 0.0001 22.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO21546.1 - 3.8e-11 43.0 0.1 2.7e-05 24.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21546.1 - 5.2e-11 41.8 1.1 0.00048 20.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KDO21546.1 - 5.6e-11 42.9 0.0 2.2e-10 40.9 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21546.1 - 7.7e-11 42.3 0.1 5.3e-08 33.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) ELMO_CED12 PF04727.13 KDO21547.1 - 2.8e-36 125.3 0.0 4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family UBM PF14377.6 KDO21547.1 - 0.00011 21.5 0.0 0.00029 20.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin binding region Vps36-NZF-N PF16988.5 KDO21547.1 - 0.044 13.2 0.2 0.09 12.2 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-HIT PF04438.16 KDO21548.1 - 6e-07 29.2 10.8 1.4e-06 28.1 10.8 1.6 1 1 0 1 1 1 1 HIT zinc finger HypA PF01155.19 KDO21548.1 - 0.036 14.1 1.2 0.064 13.3 1.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 KDO21548.1 - 0.28 11.4 4.7 0.59 10.4 4.7 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PBP1_TM PF14812.6 KDO21548.1 - 0.68 10.3 3.8 1.3 9.4 3.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4485 PF14846.6 KDO21549.1 - 0.039 14.0 1.1 0.78 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) TAF6_C PF07571.13 KDO21549.1 - 0.081 13.3 0.6 3.1 8.2 0.0 2.9 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain zinc_ribbon_6 PF14599.6 KDO21550.1 - 9.3e-23 80.0 2.9 9.3e-23 80.0 2.9 4.6 4 2 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 KDO21550.1 - 1.2e-18 67.4 27.1 1.2e-18 67.4 27.1 4.0 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KDO21550.1 - 1.1e-07 32.0 9.7 1.1e-07 32.0 9.7 5.2 2 1 5 7 7 7 1 Ring finger domain zf-RING_5 PF14634.6 KDO21550.1 - 0.0028 17.6 9.4 0.0028 17.6 9.4 6.3 2 1 2 4 4 4 1 zinc-RING finger domain PAP2_C PF14360.6 KDO21551.1 - 2.4e-16 60.0 13.6 2.4e-16 60.0 13.6 2.8 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KDO21551.1 - 0.006 16.3 5.5 0.006 16.3 5.5 3.1 2 2 1 3 3 3 1 PAP2 superfamily Phage_holin_2_4 PF16082.5 KDO21551.1 - 0.33 10.7 2.6 6.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Acetyltransf_3 PF13302.7 KDO21552.1 - 3.8e-10 40.6 0.0 5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO21552.1 - 5.1e-06 26.7 0.0 7.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Phage_holin_7_1 PF16081.5 KDO21553.1 - 0.81 9.9 2.5 8.5 6.6 0.1 2.9 3 0 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF4168 PF13767.6 KDO21554.1 - 0.47 11.7 5.4 0.88 10.8 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Pkip-1 PF06878.11 KDO21555.1 - 0.14 12.2 0.1 0.32 11.1 0.0 1.5 2 0 0 2 2 2 0 Pkip-1 protein DUF3986 PF13143.6 KDO21557.1 - 0.08 13.9 0.0 0.18 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) Rgp1 PF08737.10 KDO21557.1 - 0.24 10.5 1.2 0.34 10.0 1.2 1.1 1 0 0 1 1 1 0 Rgp1 Asp PF00026.23 KDO21558.1 - 3.9e-26 92.2 1.0 2.6e-25 89.5 1.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO21558.1 - 9.2e-22 78.1 1.7 1.4e-21 77.5 1.7 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO21558.1 - 1.2e-12 48.0 0.0 3.8e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal PMP1_2 PF08114.11 KDO21558.1 - 0.044 13.5 0.6 0.1 12.3 0.6 1.6 1 0 0 1 1 1 0 ATPase proteolipid family PRIMA1 PF16101.5 KDO21558.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 A_deaminase PF00962.22 KDO21563.1 - 5.1e-54 183.8 0.1 4.4e-32 111.7 0.1 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase Asp PF00026.23 KDO21564.1 - 1e-25 90.9 0.0 1.5e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO21564.1 - 2.2e-19 70.4 2.3 3.2e-19 69.8 2.3 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO21564.1 - 6.5e-10 39.0 0.0 3.5e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal ANAPC5 PF12862.7 KDO21565.1 - 1.6e-18 66.5 6.5 2e-17 63.0 1.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KDO21565.1 - 0.00044 20.5 3.4 0.00044 20.5 3.4 5.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO21565.1 - 0.0093 15.8 3.8 6.3 6.8 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO21565.1 - 0.24 11.5 9.2 3.4 7.9 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TAXi_N PF14543.6 KDO21566.1 - 4.6e-24 85.6 6.3 9.2e-24 84.6 6.3 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 KDO21566.1 - 1.2e-18 67.6 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KDO21566.1 - 3.5e-09 36.6 0.0 6.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Rubredoxin PF00301.20 KDO21568.1 - 0.52 10.4 13.3 6.7 6.8 0.1 4.8 5 0 0 5 5 5 0 Rubredoxin zf-BED PF02892.15 KDO21568.1 - 0.67 10.0 27.9 0.6 10.2 0.9 5.5 4 1 0 4 4 4 0 BED zinc finger zinc_ribbon_4 PF13717.6 KDO21568.1 - 1.9 8.4 14.9 14 5.7 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain F-box_4 PF15966.5 KDO21568.1 - 4 7.4 7.9 35 4.3 0.1 3.9 4 0 0 4 4 4 0 F-box ALAD PF00490.21 KDO21569.1 - 4.2e-93 312.0 0.1 8.4e-85 284.7 1.7 2.0 1 1 1 2 2 2 2 Delta-aminolevulinic acid dehydratase PAC3 PF10178.9 KDO21570.1 - 6.5e-16 58.2 0.0 1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 OAD_beta PF03977.13 KDO21570.1 - 0.076 12.0 0.2 0.078 12.0 0.2 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit NTP_transf_2 PF01909.23 KDO21571.1 - 0.00015 22.0 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KDO21571.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase tRNA-synt_1b PF00579.25 KDO21572.1 - 5.6e-21 75.1 0.0 2.1e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 KDO21572.1 - 1.8e-12 47.2 0.7 1.8e-12 47.2 0.7 2.4 2 0 0 2 2 2 1 WHEP-TRS domain Arf PF00025.21 KDO21573.1 - 3.4e-51 173.2 0.0 4e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KDO21573.1 - 4e-11 42.8 0.0 4.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO21573.1 - 5e-11 42.9 0.0 6.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO21573.1 - 2.4e-08 33.6 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO21573.1 - 2.1e-07 30.5 0.4 0.00082 18.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO21573.1 - 5.3e-07 29.7 0.0 7.7e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO21573.1 - 0.00041 19.8 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KDO21573.1 - 0.003 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B 6PF2K PF01591.18 KDO21573.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 KDO21573.1 - 0.046 13.6 0.0 5.7 6.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KDO21573.1 - 0.063 13.3 0.0 0.08 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KDO21574.1 - 1.2e-52 177.9 0.0 1.3e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO21574.1 - 8.4e-12 45.4 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO21574.1 - 8.5e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KDO21574.1 - 2.7e-06 26.8 0.1 0.0051 16.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KDO21574.1 - 2.6e-05 23.7 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO21574.1 - 0.003 17.6 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO21574.1 - 0.0038 16.6 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 KDO21574.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 KDO21575.1 - 5.4e-70 234.4 0.0 6.4e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO21575.1 - 1.3e-13 51.2 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO21575.1 - 1.1e-12 47.8 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KDO21575.1 - 1e-11 44.6 0.8 4e-08 32.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KDO21575.1 - 1.4e-11 44.2 0.0 1.8e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KDO21575.1 - 4.9e-08 32.6 0.0 6.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO21575.1 - 0.00094 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KDO21575.1 - 0.16 11.5 0.5 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KDO21576.1 - 2.9e-28 98.5 0.0 1.7e-21 76.4 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KDO21576.1 - 0.0067 15.9 0.0 0.009 15.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit 6PF2K PF01591.18 KDO21576.1 - 0.017 14.5 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Roc PF08477.13 KDO21576.1 - 0.032 14.5 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KDO21576.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 KDO21576.1 - 0.11 11.7 0.0 0.27 10.3 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit MIF4G PF02854.19 KDO21577.1 - 5.9e-43 147.0 1.6 7.8e-43 146.6 1.6 1.2 1 0 0 1 1 1 1 MIF4G domain Ank_5 PF13857.6 KDO21578.1 - 6.6e-11 42.2 7.0 0.048 14.0 0.0 6.8 5 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO21578.1 - 7e-11 42.6 5.0 0.0011 19.5 0.1 5.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO21578.1 - 2.3e-07 30.6 4.6 1.1 10.0 0.0 7.8 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.6 KDO21578.1 - 6.3e-07 29.8 13.3 3.3 8.4 0.1 8.0 6 2 0 6 6 6 4 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO21579.1 - 1.8e-37 129.2 0.0 2.1e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21579.1 - 4.4e-35 121.2 0.0 5.2e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21579.1 - 0.0022 17.4 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO21579.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO21579.1 - 0.0098 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO21579.1 - 0.059 12.7 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dymeclin PF09742.9 KDO21580.1 - 2.7e-42 145.0 2.7 3.1e-42 144.9 2.7 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KDO21580.1 - 0.079 11.1 0.3 0.86 7.7 0.1 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein HPP PF04982.13 KDO21580.1 - 1.2 9.3 7.3 0.88 9.8 0.6 2.7 2 1 1 3 3 3 0 HPP family DDE_Tnp_1_7 PF13843.6 KDO21582.1 - 0.03 13.6 0.1 0.035 13.4 0.1 1.1 1 0 0 1 1 1 0 Transposase IS4 NMD3 PF04981.13 KDO21582.1 - 0.067 12.6 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 NMD3 family PH PF00169.29 KDO21583.1 - 6.9e-15 55.5 0.0 8.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO21583.1 - 1.1e-08 35.4 0.1 2.2e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO21583.1 - 0.00067 19.9 0.3 0.007 16.6 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO21583.1 - 0.0036 17.7 0.1 0.14 12.6 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KDO21584.1 - 8.6e-10 39.1 0.0 1.4e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO21584.1 - 3.5e-06 27.4 0.0 6.4e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO21584.1 - 0.024 14.9 0.2 0.39 11.0 0.2 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Forkhead PF00250.18 KDO21585.1 - 6.3e-08 32.8 0.2 1.3e-07 31.7 0.2 1.5 1 1 0 1 1 1 1 Forkhead domain PHD PF00628.29 KDO21585.1 - 7.4e-06 25.8 6.5 1.5e-05 24.8 6.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KDO21585.1 - 0.0088 16.3 4.7 0.0088 16.3 4.7 1.7 1 1 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KDO21585.1 - 0.079 12.5 1.3 0.2 11.2 1.3 1.7 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KDO21585.1 - 0.15 12.2 5.4 0.077 13.2 3.2 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-CCCH_4 PF18044.1 KDO21590.1 - 0.093 12.6 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger NOG1_N PF17835.1 KDO21591.1 - 2.3e-55 186.9 1.2 2.3e-55 186.9 1.2 2.3 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KDO21591.1 - 3.3e-27 94.0 0.1 8.6e-27 92.7 0.1 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KDO21591.1 - 1.5e-23 82.5 1.6 3.7e-23 81.3 1.6 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KDO21591.1 - 4.5e-17 62.2 0.0 1.1e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO21591.1 - 8.2e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO21591.1 - 0.038 14.1 0.0 5.7 7.0 0.0 2.8 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 KDO21591.1 - 0.081 13.3 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 KDO21593.1 - 1.2e-15 57.9 5.3 7.2e-06 26.5 0.0 4.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21593.1 - 1e-12 48.3 11.6 0.0038 17.8 0.1 6.0 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21593.1 - 3.3e-11 43.2 11.6 0.074 13.4 0.1 8.2 3 2 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21593.1 - 7.3e-08 32.1 2.5 13 6.8 0.0 8.1 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 KDO21593.1 - 0.00047 20.5 3.5 3.7 8.2 0.0 5.8 4 2 1 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 KDO21593.1 - 0.0033 17.3 0.1 44 4.1 0.0 5.4 5 2 2 7 7 7 0 Domain of unknown function (DUF5049) AMP-binding PF00501.28 KDO21594.1 - 1.1e-67 228.6 0.1 1.8e-67 227.8 0.1 1.4 1 1 0 1 1 1 1 AMP-binding enzyme FixP_N PF14715.6 KDO21595.1 - 0.067 12.9 0.6 0.24 11.2 0.6 2.0 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Ank_3 PF13606.6 KDO21596.1 - 0.14 12.8 0.0 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat EF-hand_7 PF13499.6 KDO21597.1 - 4.3e-18 65.5 6.5 7.6e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO21597.1 - 1.8e-16 58.6 1.7 1.3e-05 24.7 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KDO21597.1 - 1.2e-14 52.7 0.1 7.3e-05 22.0 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KDO21597.1 - 2.5e-10 39.4 0.4 0.00077 18.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO21597.1 - 2.7e-07 30.3 1.7 0.009 15.8 0.0 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KDO21597.1 - 0.00013 22.2 0.5 0.016 15.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain AF-4 PF05110.13 KDO21597.1 - 0.0033 15.6 1.1 0.0033 15.6 1.1 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein IMUP PF15761.5 KDO21597.1 - 0.04 14.6 3.0 0.04 14.6 3.0 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Dockerin_1 PF00404.18 KDO21597.1 - 0.079 13.2 1.1 0.94 9.7 0.0 2.8 2 1 1 3 3 3 0 Dockerin type I domain TUDOR_5 PF18359.1 KDO21598.1 - 8.4e-115 374.4 73.8 2.8e-10 39.7 0.3 16.1 16 0 0 16 16 16 14 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 KDO21598.1 - 9.7e-58 191.8 45.9 0.00022 21.0 0.0 16.4 16 0 0 16 16 16 13 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 KDO21598.1 - 8.7e-48 160.6 38.8 0.00013 22.3 0.1 16.5 17 1 1 18 18 16 13 Agenet domain DUF4537 PF15057.6 KDO21598.1 - 4.6e-36 123.5 29.3 1.4e-05 25.1 0.2 12.2 4 1 7 13 13 11 10 Domain of unknown function (DUF4537) PUB PF09409.10 KDO21598.1 - 1.1e-31 108.5 0.0 4.4e-12 45.8 0.0 3.5 3 0 0 3 3 3 3 PUB domain Tudor_2 PF18104.1 KDO21598.1 - 1.1e-29 101.8 64.3 0.00082 19.0 0.5 15.6 16 0 0 16 16 16 11 Jumonji domain-containing protein 2A Tudor domain 53-BP1_Tudor PF09038.10 KDO21598.1 - 6.6e-29 100.3 44.9 0.034 14.1 0.3 14.0 10 2 5 15 15 14 12 Tumour suppressor p53-binding protein-1 Tudor DUF1325 PF07039.11 KDO21598.1 - 2.7e-25 89.0 26.5 0.036 14.2 0.0 13.0 6 3 8 14 14 14 9 SGF29 tudor-like domain Rad9_Rad53_bind PF08605.10 KDO21598.1 - 1.6e-14 54.2 18.3 1.9 8.7 0.0 12.9 13 1 1 14 14 13 2 Fungal Rad9-like Rad53-binding LBR_tudor PF09465.10 KDO21598.1 - 9.3e-09 35.0 56.6 0.33 10.8 0.2 14.2 14 1 1 15 15 15 6 Lamin-B receptor of TUDOR domain EF-hand_7 PF13499.6 KDO21598.1 - 1.7e-08 34.8 0.0 5.1e-06 26.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair DUF4772 PF15997.5 KDO21598.1 - 2.5e-08 34.5 7.6 5.5 7.6 0.0 9.0 8 2 0 9 9 7 2 Domain of unknown function (DUF4772) EF-hand_6 PF13405.6 KDO21598.1 - 3.1e-07 29.8 0.2 1.2 9.3 0.0 4.9 4 0 0 4 4 4 2 EF-hand domain PWWP PF00855.17 KDO21598.1 - 1.9e-06 28.2 0.0 1.8e+02 2.6 0.0 9.0 9 1 0 9 9 9 0 PWWP domain EF-hand_1 PF00036.32 KDO21598.1 - 0.0001 21.6 0.0 0.074 12.6 0.2 3.7 4 0 0 4 4 4 1 EF hand TUDOR PF00567.24 KDO21598.1 - 0.00031 20.7 13.8 2.5 8.1 0.0 8.8 10 1 0 10 10 10 1 Tudor domain TTD PF12148.8 KDO21598.1 - 0.0092 15.9 12.8 12 5.7 0.1 6.3 3 3 3 6 6 6 0 Tandem tudor domain within UHRF1 EF-hand_5 PF13202.6 KDO21598.1 - 0.028 13.9 0.2 0.14 11.7 0.2 2.3 1 0 0 1 1 1 0 EF hand Strabismus PF06638.11 KDO21598.1 - 0.2 10.3 0.3 10 4.7 0.1 3.1 3 0 0 3 3 3 0 Strabismus protein Ge1_WD40 PF16529.5 KDO21598.1 - 0.97 8.3 5.1 1e+02 1.7 0.0 5.3 7 0 0 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_8 PF13833.6 KDO21598.1 - 3.3 7.7 8.9 0.29 11.0 0.2 3.1 4 0 0 4 4 3 0 EF-hand domain pair Asp PF00026.23 KDO21598.1 - 5.2 6.4 13.4 2.7 7.4 0.1 5.0 7 0 0 7 7 6 0 Eukaryotic aspartyl protease FMN_red PF03358.15 KDO21599.1 - 4.1e-18 65.6 0.0 6.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO21599.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin-like fold FMN_red PF03358.15 KDO21600.1 - 3.8e-28 98.2 0.0 5.2e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO21600.1 - 0.0025 17.6 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold UDPG_MGDP_dh_C PF03720.15 KDO21600.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SDF PF00375.18 KDO21602.1 - 5.6e-50 170.5 22.7 3e-49 168.1 22.7 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO21603.1 - 7.6e-50 170.0 27.8 3.9e-49 167.7 27.8 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Pkinase_Tyr PF07714.17 KDO21604.1 - 9.7e-11 41.4 0.0 9.6e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21604.1 - 2.5e-10 40.2 0.0 1.3e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Thiolase_C PF02803.18 KDO21605.1 - 3.9e-39 133.1 3.5 1.4e-37 128.1 1.8 2.1 1 1 1 2 2 2 2 Thiolase, C-terminal domain Thiolase_N PF00108.23 KDO21605.1 - 1.5e-26 93.3 3.6 1.5e-14 54.0 0.1 2.6 2 1 1 3 3 3 2 Thiolase, N-terminal domain Nebulin PF00880.18 KDO21605.1 - 0.034 14.1 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Nebulin repeat Thiamine_BP PF01910.17 KDO21606.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Thiamine-binding protein Elicitin PF00964.17 KDO21607.1 - 0.11 12.6 20.8 0.087 12.9 0.9 3.3 3 0 0 3 3 3 0 Elicitin FHA PF00498.26 KDO21609.1 - 1.5e-18 66.9 0.0 2.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO21609.1 - 2.1e-08 34.4 0.0 1e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF1192 PF06698.11 KDO21609.1 - 0.022 14.8 1.9 0.022 14.8 1.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FlxA PF14282.6 KDO21609.1 - 0.077 13.0 15.2 5.1 7.2 13.6 2.6 2 0 0 2 2 2 0 FlxA-like protein ABC_tran_CTD PF16326.5 KDO21609.1 - 2.8 8.3 24.0 0.35 11.2 6.3 4.1 4 0 0 4 4 4 0 ABC transporter C-terminal domain CCDC-167 PF15188.6 KDO21609.1 - 4 7.8 15.4 3.1 8.2 1.0 3.6 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 CENP-B_dimeris PF09026.10 KDO21609.1 - 5.8 7.4 11.4 33 4.9 6.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Kazal_2 PF07648.15 KDO21610.1 - 7e-19 67.7 31.1 1.9e-08 34.3 5.0 3.2 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO21610.1 - 8.2e-19 67.4 28.6 1.3e-10 41.1 3.4 3.3 1 1 2 3 3 3 2 Kazal-type serine protease inhibitor domain PT PF04886.12 KDO21610.1 - 0.3 10.7 22.1 1.1 8.9 22.1 2.0 1 1 0 1 1 1 0 PT repeat BTB_2 PF02214.22 KDO21611.1 - 4.2e-13 49.4 0.0 9.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KDO21613.1 - 2.6e-28 98.4 8.0 2.8e-09 37.4 0.6 4.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21613.1 - 2e-25 88.8 3.5 3e-06 27.7 0.1 5.7 3 2 3 6 6 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21613.1 - 1.4e-19 68.1 8.7 0.12 13.0 0.0 7.9 8 0 0 8 8 7 5 Ankyrin repeat Ank_5 PF13857.6 KDO21613.1 - 4.8e-18 65.0 5.1 0.00013 22.2 0.0 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO21613.1 - 1.5e-17 63.2 12.9 0.009 16.4 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat TPR_2 PF07719.17 KDO21613.1 - 2e-10 39.9 6.5 0.0012 18.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO21613.1 - 3.5e-10 39.3 4.6 0.00053 19.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO21613.1 - 3.4e-07 30.8 4.1 0.00068 20.2 0.5 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO21613.1 - 5.1e-07 29.3 3.9 1.3e-06 27.9 0.4 2.5 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KDO21613.1 - 0.00051 20.3 3.9 0.78 10.1 2.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO21613.1 - 0.00084 19.4 1.8 0.0019 18.3 0.9 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO21613.1 - 0.0044 17.3 4.8 0.74 10.3 1.8 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO21613.1 - 0.0046 17.2 2.4 0.013 15.7 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KDO21613.1 - 0.02 15.7 3.5 9.9 7.3 0.0 4.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO21613.1 - 0.29 11.5 4.1 6.3 7.3 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO21613.1 - 0.95 10.0 11.0 0.97 10.0 3.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Carb_anhydrase PF00194.21 KDO21617.1 - 6.6e-35 120.9 0.0 1.3e-34 119.9 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.7 KDO21618.1 - 9.4e-22 77.4 17.6 2.1e-07 31.4 1.6 6.9 2 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21618.1 - 1.3e-20 73.5 23.6 2.4e-06 28.0 0.4 8.9 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21618.1 - 2.2e-11 43.8 22.6 0.16 12.3 0.1 10.7 6 2 5 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21618.1 - 2.1e-06 27.6 15.7 5.8 7.8 0.1 9.9 11 1 1 12 12 12 2 Ankyrin repeat DUF249 PF03158.13 KDO21618.1 - 0.036 13.8 0.7 7.2 6.3 0.0 3.5 4 0 0 4 4 4 0 Multigene family 530 protein BTB_2 PF02214.22 KDO21620.1 - 3.4e-13 49.7 0.0 2.1e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KDO21620.1 - 7.2e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KDO21620.1 - 0.034 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 KDO21621.1 - 8e-13 48.6 0.0 2.4e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KDO21621.1 - 7.1e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Atg14 PF10186.9 KDO21621.1 - 0.03 13.4 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BTB PF00651.31 KDO21621.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 KDO21622.1 - 6.3e-13 48.9 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KDO21622.1 - 0.045 13.9 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_S10 PF00450.22 KDO21623.1 - 4.9e-99 332.6 0.0 6e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KDO21623.1 - 0.0019 18.9 4.6 0.0091 16.6 2.0 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KDO21623.1 - 0.12 11.9 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Isochorismatase PF00857.20 KDO21624.1 - 2.3e-31 109.3 0.2 2.6e-31 109.1 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family Catalase_C PF18011.1 KDO21624.1 - 0.06 13.0 0.1 0.33 10.6 0.0 2.1 2 1 0 2 2 2 0 C-terminal domain found in long catalases ZZ PF00569.17 KDO21625.1 - 2.3e-14 52.9 19.7 2.1e-09 37.0 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 KDO21625.1 - 4.6e-06 26.8 15.8 0.0034 17.7 2.3 2.6 2 0 0 2 2 2 2 C1 domain AAA_5 PF07728.14 KDO21626.1 - 1.1e-119 394.8 0.0 1.8e-21 76.6 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KDO21626.1 - 2.2e-52 175.7 0.2 5.4e-16 58.7 0.0 6.7 6 0 0 6 6 5 4 Midasin AAA lid domain AAA_3 PF07726.11 KDO21626.1 - 1.1e-30 106.1 0.0 5.7e-10 39.1 0.0 7.6 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KDO21626.1 - 1.8e-25 89.1 0.2 5.8e-25 87.4 0.2 2.0 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 KDO21626.1 - 4.1e-25 88.7 0.0 0.00025 21.5 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO21626.1 - 2.7e-24 85.7 0.3 0.00093 18.8 0.0 6.6 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_22 PF13401.6 KDO21626.1 - 2.5e-20 73.2 7.4 0.0061 16.8 0.1 8.6 7 2 0 7 7 6 6 AAA domain Dynein_heavy PF03028.15 KDO21626.1 - 2.6e-19 69.5 0.0 0.0011 19.1 0.0 6.2 6 0 0 6 6 5 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 KDO21626.1 - 2.8e-19 70.1 31.8 0.0021 18.5 0.1 9.4 8 2 0 9 9 6 5 AAA ATPase domain TsaE PF02367.17 KDO21626.1 - 1.1e-16 61.0 1.7 0.0027 17.7 0.0 6.7 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KDO21626.1 - 4.2e-16 58.8 0.8 0.18 10.7 0.0 8.1 8 0 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 KDO21626.1 - 5.6e-16 58.7 0.0 0.0076 16.0 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.6 KDO21626.1 - 7.8e-16 58.8 0.0 0.36 11.4 0.0 6.8 6 0 0 6 6 6 4 AAA domain ABC_tran PF00005.27 KDO21626.1 - 4.1e-15 56.5 1.6 0.026 15.0 0.1 7.1 7 1 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.12 KDO21626.1 - 1.2e-13 50.8 4.1 0.15 11.3 0.0 7.9 7 0 0 7 7 7 3 Zeta toxin AAA_30 PF13604.6 KDO21626.1 - 1.4e-12 47.8 5.4 0.43 10.3 0.0 7.8 6 2 0 6 6 6 3 AAA domain AAA_33 PF13671.6 KDO21626.1 - 4.8e-12 46.2 2.5 0.25 11.5 0.0 7.7 7 0 0 7 7 7 1 AAA domain AAA_14 PF13173.6 KDO21626.1 - 9.3e-12 45.1 0.0 0.063 13.3 0.0 6.6 7 0 0 7 7 6 2 AAA domain NACHT PF05729.12 KDO21626.1 - 2.1e-11 44.0 1.9 0.12 12.3 0.1 6.3 6 0 0 6 6 5 2 NACHT domain AAA_29 PF13555.6 KDO21626.1 - 3.5e-10 39.5 0.3 1.4 8.8 0.0 6.6 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO21626.1 - 4e-10 39.6 9.9 0.0047 16.5 0.4 6.2 6 0 0 6 6 6 3 AAA domain RNA_helicase PF00910.22 KDO21626.1 - 6.9e-10 39.3 0.2 0.081 13.3 0.0 6.5 6 0 0 6 6 6 1 RNA helicase T2SSE PF00437.20 KDO21626.1 - 1.1e-09 37.8 1.0 0.046 12.8 0.0 6.4 6 0 0 6 6 6 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KDO21626.1 - 2.4e-09 37.3 1.4 0.068 13.1 0.1 6.3 6 0 0 6 6 6 1 RsgA GTPase AAA_8 PF12780.7 KDO21626.1 - 2.4e-09 36.9 0.0 0.32 10.3 0.0 5.1 5 0 0 5 5 5 3 P-loop containing dynein motor region D4 Rad17 PF03215.15 KDO21626.1 - 2.4e-09 37.4 1.5 0.86 9.5 0.0 6.0 6 0 0 6 6 6 2 Rad17 P-loop domain RuvB_N PF05496.12 KDO21626.1 - 3.5e-09 36.6 1.2 4.6 7.0 0.0 6.8 6 0 0 6 6 6 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KDO21626.1 - 7.1e-09 35.3 8.1 7.6 5.9 0.0 8.9 8 1 1 9 9 8 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KDO21626.1 - 8.3e-09 35.9 7.6 1.7 8.9 0.0 6.5 6 0 0 6 6 6 2 AAA domain Sigma54_activ_2 PF14532.6 KDO21626.1 - 1.5e-08 34.9 0.6 0.8 9.8 0.0 5.8 5 0 0 5 5 5 2 Sigma-54 interaction domain PduV-EutP PF10662.9 KDO21626.1 - 1.2e-06 28.3 3.5 0.16 11.7 0.0 5.1 6 0 0 6 6 4 2 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 KDO21626.1 - 3.3e-06 26.9 1.3 2.4 7.8 0.0 5.7 5 0 0 5 5 5 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KDO21626.1 - 8.6e-06 25.7 0.1 3.7 7.2 0.0 4.7 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 KDO21626.1 - 1.2e-05 24.8 0.0 4.4 6.7 0.0 6.0 7 0 0 7 7 7 0 Bacterial TniB protein AAA_19 PF13245.6 KDO21626.1 - 1.3e-05 25.5 10.5 15 5.9 0.0 7.7 8 1 0 8 8 6 0 AAA domain ATPase_2 PF01637.18 KDO21626.1 - 2.2e-05 24.5 0.0 24 4.8 0.0 6.0 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 KDO21626.1 - 2.8e-05 23.8 2.7 5.8 6.5 0.2 5.5 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain Roc PF08477.13 KDO21626.1 - 7e-05 23.0 4.0 21 5.4 0.0 6.3 7 0 0 7 7 6 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KDO21626.1 - 0.00016 21.0 4.2 2.2 7.4 0.0 6.0 7 0 0 7 7 7 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 KDO21626.1 - 0.00017 22.2 18.9 0.11 13.0 0.0 6.9 8 0 0 8 8 6 2 AAA domain VWA_2 PF13519.6 KDO21626.1 - 0.0011 19.5 0.1 0.0073 16.9 0.1 2.6 1 0 0 1 1 1 1 von Willebrand factor type A domain tRNA_lig_kinase PF08303.11 KDO21626.1 - 0.0024 18.0 0.2 2.4 8.2 0.0 2.6 2 0 0 2 2 2 1 tRNA ligase kinase domain MMR_HSR1 PF01926.23 KDO21626.1 - 0.0037 17.3 0.5 23 5.1 0.0 4.9 6 0 0 6 6 3 0 50S ribosome-binding GTPase cobW PF02492.19 KDO21626.1 - 0.0095 15.5 7.3 23 4.5 0.1 5.4 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KDO21626.1 - 0.011 15.0 0.1 5.5 6.1 0.1 3.7 3 0 0 3 3 3 0 KAP family P-loop domain PRK PF00485.18 KDO21626.1 - 0.011 15.5 0.0 70 3.1 0.0 4.6 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.10 KDO21626.1 - 0.021 14.3 2.0 45 3.4 0.0 5.1 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 KDO21626.1 - 0.024 14.5 0.3 12 5.6 0.0 4.1 5 0 0 5 5 3 0 Bacterial dnaA protein dNK PF01712.19 KDO21626.1 - 0.027 14.3 3.5 6.4 6.6 0.0 5.0 6 0 0 6 6 4 0 Deoxynucleoside kinase ATPase PF06745.13 KDO21626.1 - 0.031 13.6 0.2 9.5 5.5 0.0 3.6 5 0 0 5 5 3 0 KaiC TIP49 PF06068.13 KDO21626.1 - 0.069 12.4 1.6 57 2.8 0.0 4.4 5 0 0 5 5 5 0 TIP49 P-loop domain G-alpha PF00503.20 KDO21626.1 - 0.11 11.6 0.1 8.5 5.4 0.0 3.2 3 0 0 3 3 3 0 G-protein alpha subunit Cytidylate_kin PF02224.18 KDO21626.1 - 0.13 12.0 0.3 24 4.5 0.0 3.3 3 0 0 3 3 2 0 Cytidylate kinase NTPase_1 PF03266.15 KDO21626.1 - 0.2 11.5 5.9 25 4.7 0.0 5.3 6 0 0 6 6 6 0 NTPase AAA_21 PF13304.6 KDO21626.1 - 0.24 11.2 10.4 6.9 6.4 0.0 5.1 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KDO21626.1 - 0.75 8.9 2.8 48 3.0 0.0 4.4 6 0 0 6 6 5 0 NB-ARC domain MobB PF03205.14 KDO21626.1 - 8.2 6.3 6.4 54 3.7 0.1 4.6 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B PI3_PI4_kinase PF00454.27 KDO21628.1 - 8.7e-53 179.7 0.0 1.8e-52 178.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KDO21628.1 - 1.4e-13 50.4 0.0 3.7e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 FATC domain DUF4042 PF13251.6 KDO21628.1 - 0.036 13.8 3.6 0.21 11.3 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) TPR_19 PF14559.6 KDO21628.1 - 0.19 12.2 4.1 25 5.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat BTB_2 PF02214.22 KDO21630.1 - 1.5e-12 47.7 0.0 3.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KDO21630.1 - 0.031 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 KDO21631.1 - 1.5e-12 47.6 0.0 2.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 KDO21631.1 - 2.5e-06 27.6 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BTB_3 PF16017.5 KDO21631.1 - 0.00093 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KDO21633.1 - 5.1e-16 58.8 0.0 8.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HCMV_UL139 PF12507.8 KDO21634.1 - 5.8 7.3 11.2 5.7 7.4 4.5 2.3 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein NHL PF01436.21 KDO21635.1 - 2.1e-22 77.9 3.5 2.4e-07 30.4 0.7 6.6 6 0 0 6 6 6 5 NHL repeat Mobilization_B PF17511.2 KDO21635.1 - 0.0021 18.4 1.0 0.0037 17.6 1.0 1.3 1 0 0 1 1 1 1 Mobilization protein B SGL PF08450.12 KDO21635.1 - 0.011 15.4 7.3 0.081 12.5 0.6 3.9 3 2 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region tRNA-synt_2b PF00587.25 KDO21636.1 - 1.6e-24 86.9 0.0 2.9e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 KDO21636.1 - 3.3e-09 36.7 0.1 2.1e-08 34.1 0.1 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain KIAA1430 PF13879.6 KDO21637.1 - 1.1e-08 35.7 1.7 1.4e-08 35.4 0.2 2.0 3 0 0 3 3 3 1 KIAA1430 homologue Rad60-SLD PF11976.8 KDO21638.1 - 1.5e-29 101.6 0.1 5.9e-10 38.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KDO21638.1 - 7.5e-16 57.6 0.0 0.00034 20.3 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family RBD PF02196.15 KDO21638.1 - 9.3e-09 35.2 0.0 0.0021 18.1 0.0 3.2 3 0 0 3 3 3 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 KDO21638.1 - 0.00025 21.2 0.6 1.1 9.5 0.0 2.9 3 0 0 3 3 3 2 TUG ubiquitin-like domain Cobl PF09469.10 KDO21638.1 - 0.00025 21.2 0.9 0.11 12.8 0.1 3.1 2 1 0 3 3 3 2 Cordon-bleu ubiquitin-like domain peroxidase PF00141.23 KDO21639.1 - 8.3e-22 78.0 0.1 1.4e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 Peroxidase CTP_transf_1 PF01148.20 KDO21640.1 - 1.2e-33 117.1 13.2 2.2e-31 109.6 13.2 2.3 1 1 0 1 1 1 1 Cytidylyltransferase family Band_7 PF01145.25 KDO21641.1 - 1e-08 35.4 17.7 3.2e-07 30.5 17.7 2.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family Complex1_LYR PF05347.15 KDO21642.1 - 5e-10 39.3 0.0 6.4e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KDO21642.1 - 0.0032 18.0 0.0 0.0037 17.8 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 KDO21642.1 - 0.0032 18.2 0.0 0.0038 17.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Phage_holin_6_1 PF09682.10 KDO21642.1 - 0.029 14.8 0.1 0.033 14.6 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Lycopene_cycl PF05834.12 KDO21642.1 - 0.036 13.1 0.0 0.037 13.1 0.0 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein zf-BED PF02892.15 KDO21643.1 - 0.021 14.9 1.7 0.054 13.5 0.7 2.1 2 0 0 2 2 2 0 BED zinc finger DUF2418 PF10332.9 KDO21643.1 - 0.043 14.3 1.8 0.3 11.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Metallophos PF00149.28 KDO21644.1 - 2.5e-14 54.3 0.0 4.4e-14 53.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO21644.1 - 2.2e-05 24.7 0.0 0.00017 21.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 KDO21645.1 - 7.8e-82 269.9 41.6 1.6e-11 44.6 0.1 17.6 9 6 7 20 20 20 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21645.1 - 3.9e-65 215.4 45.1 3.5e-07 30.7 0.1 18.9 16 3 2 18 18 18 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21645.1 - 2.7e-59 190.1 45.5 0.017 15.6 0.0 27.6 28 0 0 28 28 28 13 Ankyrin repeat Ank_5 PF13857.6 KDO21645.1 - 2.7e-47 158.2 48.8 1.8e-07 31.3 0.1 19.5 15 4 6 21 21 21 11 Ankyrin repeats (many copies) Ank PF00023.30 KDO21645.1 - 1.5e-37 126.4 67.0 0.0012 19.2 0.1 22.3 23 0 0 23 23 23 13 Ankyrin repeat Kinesin PF00225.23 KDO21649.1 - 1.6e-103 346.1 0.0 1.6e-103 346.1 0.0 2.4 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KDO21649.1 - 3.3e-21 75.8 0.0 8.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding UCH PF00443.29 KDO21650.1 - 1.4e-51 175.5 0.2 2e-51 174.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO21650.1 - 8.6e-33 114.3 0.5 3.9e-32 112.1 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TUG-UBL1 PF11470.8 KDO21650.1 - 0.034 14.4 1.7 0.25 11.6 0.0 3.2 4 0 0 4 4 4 0 TUG ubiquitin-like domain USP7_C2 PF14533.6 KDO21650.1 - 0.065 12.9 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal DUF3389 PF11869.8 KDO21650.1 - 0.18 12.0 0.2 0.94 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) COX4_pro PF03626.14 KDO21651.1 - 0.026 14.9 1.1 0.044 14.2 1.1 1.3 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV DUF3311 PF11755.8 KDO21651.1 - 0.056 13.4 1.7 0.067 13.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Nop52 PF05997.12 KDO21652.1 - 2.9e-61 207.0 6.1 2.9e-61 207.0 6.1 1.8 2 0 0 2 2 2 1 Nucleolar protein,Nop52 COX6A PF02046.15 KDO21652.1 - 0.0025 18.3 1.2 0.0045 17.5 0.8 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Ipi1_N PF12333.8 KDO21652.1 - 0.2 12.2 1.9 10 6.8 0.0 3.0 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation WD40 PF00400.32 KDO21653.1 - 1.9e-31 107.6 9.3 5.6e-07 30.2 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.12 KDO21653.1 - 7e-12 46.2 0.2 9.7e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Striatin family ANAPC4_WD40 PF12894.7 KDO21653.1 - 1.3e-08 35.1 0.1 0.0016 18.7 0.0 5.0 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KDO21653.1 - 3.9e-06 25.9 0.0 0.26 10.0 0.0 3.8 2 2 1 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 KDO21653.1 - 0.00055 18.7 0.0 4.7 5.7 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 MAP70 PF07058.11 KDO21653.1 - 0.085 11.6 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 VPS13 PF16908.5 KDO21654.1 - 1.9e-62 211.1 0.1 4.9e-62 209.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 KDO21654.1 - 9.3e-36 123.4 0.1 2.9e-31 108.7 0.0 3.7 3 1 1 4 4 4 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 KDO21654.1 - 4.8e-35 120.9 0.0 7.4e-33 113.8 0.0 2.8 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KDO21654.1 - 1.1e-28 100.3 0.0 4.6e-23 82.0 0.0 2.8 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KDO21654.1 - 2.2e-20 72.9 0.0 8.8e-20 71.0 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 U79_P34 PF03064.16 KDO21656.1 - 0.7 9.2 4.4 0.82 9.0 4.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HAUS-augmin3 PF14932.6 KDO21658.1 - 0.03 13.9 4.3 0.032 13.8 0.9 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Hormone_1 PF00103.20 KDO21658.1 - 0.067 12.9 0.6 0.079 12.7 0.6 1.1 1 0 0 1 1 1 0 Somatotropin hormone family Tup_N PF08581.10 KDO21658.1 - 0.36 11.2 3.4 3.6 8.0 0.7 2.8 2 2 0 2 2 2 0 Tup N-terminal LRR_4 PF12799.7 KDO21659.1 - 0.0029 18.0 4.8 0.16 12.4 0.6 4.0 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO21659.1 - 0.072 13.7 0.1 13 6.8 0.1 3.6 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO21659.1 - 0.54 10.5 6.5 12 6.3 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 KDO21661.1 - 0.014 15.8 0.7 4.5 7.8 0.1 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO21661.1 - 0.81 9.9 4.4 58 4.1 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat EKLF_TAD1 PF16832.5 KDO21665.1 - 0.029 14.2 1.3 0.049 13.5 1.3 1.4 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 PX PF00787.24 KDO21666.1 - 1.5e-06 28.2 0.0 3.4e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 PX domain DUF4326 PF14216.6 KDO21667.1 - 2.1e-20 73.2 0.0 3.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) zf-RanBP PF00641.18 KDO21667.1 - 0.02 14.2 5.6 0.032 13.6 5.6 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others TMEM239 PF15841.5 KDO21669.1 - 0.00021 21.3 0.0 0.00024 21.0 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 239 family HlyE PF06109.13 KDO21670.1 - 0.00017 21.1 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Haemolysin E (HlyE) HlyE PF06109.13 KDO21671.1 - 0.0038 16.6 0.0 0.0079 15.6 0.0 1.4 1 1 0 1 1 1 1 Haemolysin E (HlyE) TPR_MLP1_2 PF07926.12 KDO21671.1 - 0.022 14.8 1.3 0.035 14.2 1.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LRR_9 PF14580.6 KDO21673.1 - 0.0095 15.4 0.6 1.4 8.4 0.0 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KDO21673.1 - 0.14 12.3 6.5 0.38 10.9 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat MRP-S25 PF13741.6 KDO21674.1 - 0.053 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 La_HTH_kDCL PF18177.1 KDO21675.1 - 0.14 12.4 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain OB_RNB PF08206.11 KDO21676.1 - 0.041 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain Spt5_N PF11942.8 KDO21676.1 - 2.4 9.2 6.2 3.3 8.8 5.9 1.3 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 KDO21677.1 - 2.2e-36 125.6 0.0 2.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21677.1 - 2.8e-31 108.8 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO21677.1 - 5.2e-05 22.2 0.0 9.2e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO21677.1 - 0.00082 18.8 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO21677.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_19 PF14559.6 KDO21678.1 - 0.031 14.8 4.6 0.063 13.8 0.3 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat LLC1 PF14945.6 KDO21679.1 - 0.0081 16.7 0.2 0.012 16.2 0.2 1.2 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Elicitin PF00964.17 KDO21680.1 - 0.0011 19.0 0.7 0.0025 17.9 0.5 1.8 1 1 0 1 1 1 1 Elicitin ABC_tran PF00005.27 KDO21681.1 - 1.2e-28 100.4 0.0 2.3e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO21681.1 - 2.2e-25 89.9 9.3 3.3e-25 89.3 9.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO21681.1 - 9.1e-08 31.8 0.8 1.3e-05 24.7 0.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO21681.1 - 0.00038 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KDO21681.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO21681.1 - 0.0028 17.4 0.2 0.0078 15.9 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO21681.1 - 0.011 16.1 0.5 0.13 12.6 0.5 2.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KDO21681.1 - 0.013 15.3 0.3 0.64 9.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KDO21681.1 - 0.032 13.8 0.0 0.61 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 KDO21681.1 - 0.037 12.8 0.2 0.44 9.3 0.1 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 KDO21681.1 - 0.038 14.4 1.4 10 6.5 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO21681.1 - 0.049 13.4 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KDO21681.1 - 0.055 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KDO21681.1 - 0.067 13.4 0.1 0.25 11.6 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KDO21681.1 - 0.087 12.7 0.1 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KDO21681.1 - 0.12 12.3 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_membrane_2 PF06472.15 KDO21681.1 - 0.14 11.5 2.1 0.59 9.5 2.2 1.9 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 FeS PF04060.13 KDO21682.1 - 0.027 14.1 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 Putative Fe-S cluster Elicitin PF00964.17 KDO21683.1 - 0.0013 18.8 0.0 0.0013 18.8 0.0 2.0 2 1 0 2 2 2 1 Elicitin DUF1631 PF07793.11 KDO21683.1 - 0.072 11.5 1.4 0.076 11.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SOG2 PF10428.9 KDO21683.1 - 6 5.9 15.7 7.8 5.6 15.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.7 KDO21684.1 - 2.3e-26 92.2 14.4 6.3e-08 33.1 0.2 6.9 5 1 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21684.1 - 4.4e-18 65.4 24.4 0.009 16.6 0.1 11.5 8 3 6 14 14 14 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21684.1 - 1.4e-10 41.2 28.2 0.24 11.8 0.1 11.8 6 3 9 15 15 15 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21684.1 - 2.4e-09 36.6 13.8 9 7.2 0.0 11.9 12 1 1 13 13 13 1 Ankyrin repeat DUF5049 PF16468.5 KDO21684.1 - 6.5e-06 25.9 0.0 1.5 8.8 0.1 5.5 7 1 0 7 7 7 2 Domain of unknown function (DUF5049) VWA_3_C PF18571.1 KDO21684.1 - 0.16 11.8 0.5 29 4.6 0.0 4.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain DUF5511 PF17630.2 KDO21684.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5511) EamA PF00892.20 KDO21685.1 - 2.8e-16 60.0 38.3 3.3e-11 43.5 16.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family Med4 PF10018.9 KDO21688.1 - 0.03 14.0 0.3 0.03 14.0 0.3 3.5 4 1 0 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 ArAE_2_N PF10337.9 KDO21688.1 - 0.54 9.2 4.9 0.12 11.4 1.4 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Folliculin PF11704.8 KDO21688.1 - 1.9 8.3 5.3 0.53 10.1 1.8 1.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DDHD PF02862.17 KDO21688.1 - 2.1 8.5 4.8 1.4 9.0 2.3 1.9 2 0 0 2 2 2 0 DDHD domain CALCOCO1 PF07888.11 KDO21689.1 - 2.1e-05 23.6 7.0 5.7e-05 22.2 7.0 1.6 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Flagellin_N PF00669.20 KDO21689.1 - 0.00042 20.4 3.7 0.00042 20.4 3.7 2.2 2 0 0 2 2 2 1 Bacterial flagellin N-terminal helical region HrpB7 PF09486.10 KDO21689.1 - 0.00069 20.0 1.0 0.00069 20.0 1.0 3.0 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) FliJ PF02050.16 KDO21689.1 - 0.00071 19.8 21.2 0.001 19.3 6.1 2.4 2 0 0 2 2 2 1 Flagellar FliJ protein Fib_alpha PF08702.10 KDO21689.1 - 0.00077 19.7 5.7 0.011 15.9 1.0 2.3 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KDO21689.1 - 0.00095 19.6 5.0 1 9.9 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function DUF16 DUF4407 PF14362.6 KDO21689.1 - 0.0053 16.1 15.9 0.02 14.3 3.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) MscS_porin PF12795.7 KDO21689.1 - 0.015 14.8 9.4 0.015 14.8 9.4 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain STAT_alpha PF01017.20 KDO21689.1 - 0.017 15.0 8.8 0.68 9.8 0.6 2.4 2 0 0 2 2 2 0 STAT protein, all-alpha domain APG6_N PF17675.1 KDO21689.1 - 0.019 15.5 1.6 0.019 15.5 1.6 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region CdvA PF18822.1 KDO21689.1 - 0.027 14.3 3.7 0.23 11.3 0.3 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain NPV_P10 PF05531.12 KDO21689.1 - 0.053 14.0 4.0 0.96 10.0 0.5 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 KDO21689.1 - 0.056 13.2 6.3 0.46 10.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.14 KDO21689.1 - 0.098 12.5 1.2 0.27 11.1 0.1 2.3 2 1 1 3 3 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 KDO21689.1 - 0.1 12.7 6.0 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KDO21689.1 - 0.11 12.8 3.1 0.3 11.4 0.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 KDO21689.1 - 0.21 11.9 9.0 0.2 12.1 1.0 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels V_ATPase_I PF01496.19 KDO21689.1 - 0.6 8.0 4.4 4.6 5.0 0.3 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 KDO21689.1 - 0.62 10.3 18.1 0.098 12.9 5.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cluap1 PF10234.9 KDO21689.1 - 0.79 9.1 8.4 0.7 9.2 0.4 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 HSCB_C PF07743.13 KDO21689.1 - 0.85 10.2 10.4 0.18 12.3 0.5 3.5 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain FlxA PF14282.6 KDO21689.1 - 1 9.4 9.7 0.28 11.2 3.4 2.4 2 0 0 2 2 2 0 FlxA-like protein HMMR_N PF15905.5 KDO21689.1 - 1.1 8.7 10.4 0.046 13.2 1.9 2.2 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 KDO21689.1 - 1.2 9.1 11.1 5.7 7.0 0.7 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KDO21689.1 - 1.3 8.4 9.0 0.42 9.9 0.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KDO21689.1 - 2 8.6 5.5 0.98 9.6 1.7 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.6 KDO21689.1 - 2.3 8.6 7.7 1.8 9.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF5082 PF16888.5 KDO21689.1 - 2.5 8.4 9.6 3.2 8.0 1.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) PRKG1_interact PF15898.5 KDO21689.1 - 3 8.8 10.3 3.6 8.5 1.1 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 KDO21689.1 - 3 7.9 16.2 2.4 8.2 2.1 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KDO21689.1 - 3.1 6.3 7.7 45 2.5 7.3 2.0 1 1 0 1 1 1 0 AAA domain FliT PF05400.13 KDO21689.1 - 4.6 8.1 15.9 0.28 12.0 1.0 3.6 2 1 1 3 3 3 0 Flagellar protein FliT Matrilin_ccoil PF10393.9 KDO21689.1 - 4.8 7.1 7.2 1.8 8.5 0.6 3.3 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin BST2 PF16716.5 KDO21689.1 - 5.2 7.7 15.8 8.1 7.1 1.9 2.9 2 2 1 3 3 3 0 Bone marrow stromal antigen 2 TMF_TATA_bd PF12325.8 KDO21689.1 - 6.9 6.9 10.9 0.67 10.2 2.6 2.8 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DHR10 PF18595.1 KDO21689.1 - 7.8 6.6 20.2 0.4 10.7 3.7 2.9 3 1 0 3 3 2 0 Designed helical repeat protein 10 domain DUF4140 PF13600.6 KDO21689.1 - 9.1 6.8 13.4 4.7 7.7 4.0 3.1 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 KDO21689.1 - 9.1 6.6 12.4 1.1 9.6 2.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 KDO21689.1 - 9.4 6.6 12.5 2.7 8.4 2.7 2.4 2 0 0 2 2 2 0 YlqD protein DUF2968 PF11180.8 KDO21689.1 - 10 5.7 23.0 0.73 9.4 7.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CRAL_TRIO_2 PF13716.6 KDO21690.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.6 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain RseC_MucC PF04246.12 KDO21690.1 - 0.04 13.9 0.1 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Sigma70_r3 PF04539.16 KDO21690.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 DUF4596 PF15363.6 KDO21691.1 - 0.057 13.7 8.2 0.06 13.6 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4596) Cellulase PF00150.18 KDO21693.1 - 1.4e-06 28.0 0.3 1.8e-06 27.6 0.3 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) OprD PF03573.13 KDO21694.1 - 0.0017 17.5 0.4 0.0019 17.3 0.4 1.1 1 0 0 1 1 1 1 outer membrane porin, OprD family DEAD_assoc PF08494.11 KDO21695.1 - 0.084 12.7 1.2 9.2 6.0 0.3 2.5 2 0 0 2 2 2 0 DEAD/H associated Ank_2 PF12796.7 KDO21696.1 - 5.9e-18 65.2 11.9 5.3e-06 26.9 0.4 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21696.1 - 2.2e-13 50.4 14.1 0.00011 22.6 0.8 5.9 4 3 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21696.1 - 4.2e-10 39.7 13.4 0.026 14.8 0.0 6.4 2 2 4 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21696.1 - 5e-10 38.7 6.7 0.87 10.4 0.1 6.6 6 0 0 6 6 6 2 Ankyrin repeat DUF5049 PF16468.5 KDO21696.1 - 0.00026 20.8 0.1 4.7 7.2 0.0 4.9 4 1 1 5 5 5 1 Domain of unknown function (DUF5049) Ank PF00023.30 KDO21696.1 - 0.056 13.9 2.5 30 5.3 0.1 4.0 3 2 0 3 3 3 0 Ankyrin repeat GHL6 PF14871.6 KDO21696.1 - 0.069 13.3 0.1 0.12 12.5 0.1 1.5 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Ank_2 PF12796.7 KDO21697.1 - 1.1e-22 80.4 10.5 1.6e-06 28.6 0.0 6.5 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21697.1 - 4.4e-16 59.0 17.3 0.0047 17.5 0.2 9.7 7 3 3 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21697.1 - 1.5e-13 50.7 17.8 0.045 14.1 0.2 9.4 2 2 7 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21697.1 - 9.6e-10 37.9 8.2 54 4.8 0.0 9.9 10 0 0 10 10 10 0 Ankyrin repeat DUF5049 PF16468.5 KDO21697.1 - 9.4e-05 22.2 0.4 1.1 9.2 0.0 5.5 7 0 0 7 7 7 1 Domain of unknown function (DUF5049) SIS_2 PF13580.6 KDO21697.1 - 0.003 17.6 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 SIS domain Ank PF00023.30 KDO21697.1 - 0.0081 16.6 9.2 56 4.4 0.2 7.4 5 2 1 6 6 6 0 Ankyrin repeat LRR_4 PF12799.7 KDO21699.1 - 1.4e-07 31.7 0.4 7.4e-05 23.0 0.0 3.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21699.1 - 7.8e-06 25.6 0.1 0.00031 20.4 0.0 3.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 KDO21699.1 - 2e-05 24.2 15.3 0.013 15.5 0.1 6.1 6 0 0 6 6 6 2 Leucine Rich repeat PIG-S PF10510.9 KDO21699.1 - 0.19 10.5 0.5 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein BT1 PF03092.16 KDO21700.1 - 9.9e-09 34.0 5.7 9.9e-09 34.0 5.7 3.0 3 1 1 4 4 4 3 BT1 family PUCC PF03209.15 KDO21700.1 - 0.00094 18.3 0.8 0.00094 18.3 0.8 2.6 3 0 0 3 3 3 1 PUCC protein Cystatin PF00031.21 KDO21701.1 - 0.00014 22.1 0.1 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 Cystatin domain DUF4485 PF14846.6 KDO21703.1 - 0.03 14.3 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) DUF4807 PF16065.5 KDO21706.1 - 7.7e-11 41.7 1.0 1.3e-10 41.0 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) Ank_4 PF13637.6 KDO21707.1 - 3.6e-05 24.2 0.0 7.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO21707.1 - 0.00011 22.7 0.0 0.00051 20.6 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PRTP PF01366.18 KDO21707.1 - 0.088 10.8 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Ank PF00023.30 KDO21707.1 - 0.13 12.8 1.1 0.51 10.9 0.1 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KDO21707.1 - 0.2 12.0 1.1 2.2 8.7 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF2371 PF10177.9 KDO21708.1 - 4e-05 23.8 0.6 0.047 13.9 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2371) V-set_CD47 PF08204.11 KDO21708.1 - 0.047 13.7 0.2 0.13 12.3 0.1 1.7 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain PIRT PF15099.6 KDO21708.1 - 1.3 8.6 5.5 14 5.3 4.6 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family TMEM174 PF15029.6 KDO21708.1 - 8.8 6.0 6.4 6.4 6.4 0.5 2.0 1 1 1 2 2 2 0 Transmembrane protein 174 Tfb2 PF03849.14 KDO21709.1 - 7e-34 117.4 0.2 1.2e-33 116.6 0.1 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KDO21709.1 - 6.1e-20 71.4 0.1 1.6e-19 70.1 0.1 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KDO21709.1 - 0.00041 20.5 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cnd3 PF12719.7 KDO21709.1 - 0.055 12.7 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF3584 PF12128.8 KDO21710.1 - 0.16 9.5 33.7 0.049 11.2 11.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 KDO21710.1 - 0.17 11.9 31.6 0.027 14.5 12.8 4.0 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 KDO21710.1 - 0.27 10.3 17.6 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 JIP_LZII PF16471.5 KDO21710.1 - 0.57 10.4 11.3 0.079 13.1 1.6 3.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF2387 PF09526.10 KDO21710.1 - 0.58 10.3 0.1 0.58 10.3 0.1 2.6 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) ATG16 PF08614.11 KDO21710.1 - 0.86 9.8 49.3 0.3 11.3 14.2 3.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 KDO21710.1 - 1.1 9.6 20.4 5.1 7.4 1.3 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 KDO21710.1 - 1.2 8.5 24.2 0.44 10.0 12.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4472 PF14739.6 KDO21710.1 - 1.5 9.6 29.9 0.084 13.6 5.5 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4472) F_actin_bind PF08919.10 KDO21710.1 - 2.7 8.1 11.5 0.21 11.7 3.2 2.9 2 1 1 3 3 3 0 F-actin binding HALZ PF02183.18 KDO21710.1 - 3.3 8.0 11.3 8.1 6.8 0.5 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper Tho2 PF11262.8 KDO21710.1 - 3.8 6.6 12.5 2 7.5 1.1 2.4 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fib_alpha PF08702.10 KDO21710.1 - 4.2 7.6 12.4 13 6.0 0.4 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 KDO21710.1 - 6.1 7.1 11.1 3.8 7.7 3.8 4.0 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 DLP_helical PF18709.1 KDO21710.1 - 9.5 5.3 18.6 0.027 13.7 2.5 2.8 2 1 0 2 2 2 0 Dynamin-like helical domain ThiF PF00899.21 KDO21711.1 - 3.5e-12 46.2 0.0 3e-09 36.6 0.0 2.8 2 1 0 2 2 2 2 ThiF family E1_4HB PF16191.5 KDO21711.1 - 0.0001 22.4 0.4 2 8.7 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle Pkinase PF00069.25 KDO21712.1 - 1e-28 100.5 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21712.1 - 3.8e-24 85.4 0.0 6.5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 KDO21712.1 - 5.4e-12 45.4 0.0 1.3e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain C2 PF00168.30 KDO21712.1 - 3.2e-11 43.4 0.0 7.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain PDZ PF00595.24 KDO21712.1 - 2.9e-10 40.3 0.0 0.00048 20.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 KDO21712.1 - 1.2e-07 32.2 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 KDO21712.1 - 0.0011 19.2 0.0 3 8.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_11 PF15413.6 KDO21712.1 - 0.0017 18.7 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ_2 PF13180.6 KDO21712.1 - 0.0024 18.2 0.0 0.042 14.2 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Ank_2 PF12796.7 KDO21712.1 - 0.017 15.7 0.0 0.06 13.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DNase_II PF03265.15 KDO21713.1 - 8.2e-19 68.0 0.1 6.5e-18 65.1 0.1 2.1 2 1 0 2 2 2 1 Deoxyribonuclease II Tim17 PF02466.19 KDO21714.1 - 6.7e-25 87.6 2.0 8e-25 87.4 2.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Citrate_synt PF00285.21 KDO21715.1 - 2e-106 356.1 0.0 2.5e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Nicastrin PF05450.15 KDO21716.1 - 5.3e-25 88.3 1.2 1.3e-24 86.9 1.2 1.5 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 KDO21716.1 - 3.6e-17 62.9 0.0 7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 KDO21716.1 - 5.3e-11 42.6 0.4 1.2e-10 41.5 0.4 1.6 1 1 0 1 1 1 1 Peptidase family M28 SET PF00856.28 KDO21718.1 - 3.5e-09 37.3 0.3 1.7e-08 35.0 0.3 2.3 1 1 0 1 1 1 1 SET domain Sds3 PF08598.11 KDO21719.1 - 0.00011 22.3 0.0 0.00012 22.1 0.0 1.1 1 0 0 1 1 1 1 Sds3-like DUF2164 PF09932.9 KDO21719.1 - 0.016 15.3 0.2 0.039 14.0 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) TRAPPC9-Trs120 PF08626.11 KDO21720.1 - 4.8e-22 77.3 0.0 3e-17 61.4 0.0 3.1 3 0 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC-Trs85 PF12739.7 KDO21720.1 - 0.0053 15.8 3.2 0.014 14.4 3.1 1.7 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Peptidase_S24 PF00717.23 KDO21721.1 - 2.2e-09 37.1 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KDO21721.1 - 1.1e-07 31.7 0.1 0.00012 21.9 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 YqaJ PF09588.10 KDO21722.1 - 7.3e-05 23.0 0.0 0.03 14.5 0.0 2.5 2 0 0 2 2 2 2 YqaJ-like viral recombinase domain Myb_DNA-bind_4 PF13837.6 KDO21724.1 - 2e-05 24.9 1.0 7.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KDO21724.1 - 0.00011 23.1 0.7 0.00067 20.6 0.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KDO21724.1 - 0.082 13.2 1.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ubiq_cyt_C_chap PF03981.12 KDO21725.1 - 9.9e-19 67.8 0.0 1.4e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 KDO21725.1 - 0.0012 18.8 0.3 0.0026 17.8 0.3 1.6 1 0 0 1 1 1 1 WW domain NUDIX PF00293.28 KDO21725.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Porin_3 PF01459.22 KDO21726.1 - 1.5e-39 136.1 11.9 1.8e-39 135.8 11.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin ATG2_CAD PF13329.6 KDO21726.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Cu PF17563.2 KDO21726.1 - 1.4 9.2 4.0 17 5.7 0.2 2.8 2 0 0 2 2 2 0 Cupiennin DUF2892 PF11127.8 KDO21727.1 - 5.3 7.2 7.3 12 6.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Roc PF08477.13 KDO21728.1 - 1.8e-06 28.2 0.0 2.9e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO21728.1 - 2.9e-06 27.0 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 Ras family DLIC PF05783.11 KDO21728.1 - 0.025 13.4 0.0 0.062 12.1 0.0 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KDO21728.1 - 0.035 14.5 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KDO21728.1 - 0.039 13.4 0.2 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Sigma54_activat PF00158.26 KDO21728.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KDO21728.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Snf7 PF03357.21 KDO21729.1 - 5.5e-44 149.8 12.2 8e-44 149.3 12.2 1.2 1 0 0 1 1 1 1 Snf7 Fib_alpha PF08702.10 KDO21729.1 - 0.099 12.8 8.3 0.44 10.7 4.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KDO21729.1 - 0.16 12.2 3.3 8.1 6.8 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF5082 PF16888.5 KDO21729.1 - 0.2 11.9 12.3 0.2 11.9 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) PP2C_C PF07830.13 KDO21729.1 - 0.55 10.7 3.2 14 6.3 0.0 2.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain NPR2 PF06218.11 KDO21729.1 - 0.67 8.6 3.7 0.27 10.0 0.8 1.6 1 1 1 2 2 2 0 Nitrogen permease regulator 2 CCDC24 PF15669.5 KDO21729.1 - 0.69 9.8 7.8 0.23 11.3 3.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Ax_dynein_light PF10211.9 KDO21729.1 - 0.89 9.5 10.7 1.2 9.1 5.8 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DASH_Duo1 PF08651.10 KDO21729.1 - 3.4 7.5 6.7 1.6 8.5 0.5 2.8 2 1 0 2 2 2 0 DASH complex subunit Duo1 ANAPC4_WD40 PF12894.7 KDO21730.1 - 0.00029 21.1 0.0 13 6.1 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KDO21730.1 - 0.00066 20.1 0.2 0.12 13.0 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain WD40 PF00400.32 KDO21730.1 - 0.0028 18.4 1.3 14 6.7 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 KDO21730.1 - 0.028 13.8 0.0 0.49 9.7 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 KDO21730.1 - 0.056 13.0 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain CDC45 PF02724.14 KDO21730.1 - 0.3 9.3 4.7 0.4 8.9 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 KDO21730.1 - 2.6 7.7 16.1 3.5 7.3 16.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KDO21730.1 - 2.9 7.2 11.4 3.6 6.9 11.4 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KDO21730.1 - 8.1 4.8 7.1 9.8 4.6 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MMgT PF10270.9 KDO21732.1 - 1.9e-06 28.1 0.0 2.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Neurensin PF14927.6 KDO21732.1 - 0.12 12.0 0.4 0.42 10.3 0.0 1.8 1 1 1 2 2 2 0 Neurensin Complex1_LYR PF05347.15 KDO21733.1 - 2.1e-13 50.1 1.4 3.2e-13 49.5 1.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO21733.1 - 0.0013 19.5 0.1 0.0016 19.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like LSM PF01423.22 KDO21734.1 - 8.5e-17 60.6 0.2 1.5e-16 59.8 0.2 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO21734.1 - 0.00023 21.2 0.1 0.00059 19.9 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain Feld-I_B PF09252.10 KDO21734.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 1 0 1 1 1 0 Allergen Fel d I-B chain Dpy-30 PF05186.13 KDO21735.1 - 8.2e-19 67.0 1.0 1e-18 66.7 0.2 1.6 2 0 0 2 2 2 1 Dpy-30 motif DUF3736 PF12540.8 KDO21735.1 - 0.035 14.2 1.5 0.12 12.5 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3736) ADK PF00406.22 KDO21737.1 - 8.6e-60 201.2 0.0 1.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KDO21737.1 - 4.1e-25 88.8 0.3 8e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KDO21737.1 - 4.8e-18 64.8 0.0 9.1e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KDO21737.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO21737.1 - 0.13 12.8 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KDO21737.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain HD_3 PF13023.6 KDO21739.1 - 3.1e-25 89.0 0.2 3.6e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KDO21739.1 - 1.5e-08 34.6 0.1 1.8e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KDO21739.1 - 0.043 14.0 0.1 0.057 13.7 0.1 1.2 1 0 0 1 1 1 0 HD domain Helicase_C PF00271.31 KDO21741.1 - 4.5e-16 59.2 0.0 8.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO21741.1 - 4.4e-11 42.9 0.0 8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-GRF PF06839.12 KDO21741.1 - 1.5e-10 41.0 0.6 2.5e-10 40.3 0.6 1.4 1 0 0 1 1 1 1 GRF zinc finger ResIII PF04851.15 KDO21741.1 - 0.0024 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Adeno_VII PF03228.14 KDO21741.1 - 2.4 8.8 7.4 11 6.7 1.3 3.4 3 0 0 3 3 3 0 Adenoviral core protein VII NIF PF03031.18 KDO21742.1 - 1.7e-17 63.6 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metallophos PF00149.28 KDO21743.1 - 7.6e-08 33.1 0.3 3e-07 31.2 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ODV-E18 PF10717.9 KDO21743.1 - 0.96 9.4 4.6 5.1 7.0 4.6 2.2 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Metallophos PF00149.28 KDO21744.1 - 1.4e-08 35.5 0.1 1.2e-07 32.5 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase SpoIIIAH PF12685.7 KDO21745.1 - 0.18 11.6 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Y_phosphatase2 PF03162.13 KDO21746.1 - 1.7e-55 187.1 0.0 2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KDO21746.1 - 1.1e-06 28.8 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO21746.1 - 0.00049 19.7 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KDO21746.1 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Glyco_hydro_6 PF01341.17 KDO21747.1 - 8.8e-48 163.6 0.2 1.7e-47 162.7 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 DUF5325 PF17259.2 KDO21747.1 - 0.095 12.6 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5325) PilJ PF13675.6 KDO21748.1 - 0.047 13.7 0.2 0.058 13.4 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term COX14 PF14880.6 KDO21748.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly MREG PF15812.5 KDO21750.1 - 0.14 12.5 0.0 0.36 11.1 0.0 1.6 2 0 0 2 2 2 0 Melanoregulin PAM2 PF07145.15 KDO21755.1 - 0.0066 16.1 0.0 0.0066 16.1 0.0 1.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Cwf_Cwc_15 PF04889.12 KDO21755.1 - 0.12 12.1 0.6 0.17 11.6 0.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAP_N PF01213.19 KDO21755.1 - 5.7 6.3 11.5 2.4 7.6 4.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Amidohydro_1 PF01979.20 KDO21757.1 - 4.8e-64 216.8 0.1 5.9e-64 216.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KDO21757.1 - 3.3e-12 46.6 4.2 2.1e-09 37.4 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family Trypsin PF00089.26 KDO21758.1 - 2.9e-34 118.8 0.0 3.5e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin Carn_acyltransf PF00755.20 KDO21759.1 - 6.6e-176 586.4 0.0 7.5e-176 586.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase LRR_6 PF13516.6 KDO21761.1 - 1.8e-09 36.9 7.3 0.00015 21.6 0.7 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KDO21761.1 - 0.00027 21.2 5.7 0.14 12.6 1.3 3.7 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21761.1 - 0.00088 19.0 10.7 0.45 10.3 0.5 4.6 2 2 1 3 3 3 3 Leucine rich repeat Peptidase_M14 PF00246.24 KDO21762.1 - 1.5e-29 103.7 0.0 1.8e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF3352 PF11832.8 KDO21762.1 - 0.055 12.1 0.1 0.077 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) DUF2817 PF10994.8 KDO21762.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) LRR_6 PF13516.6 KDO21763.1 - 2.1e-09 36.7 1.6 0.0034 17.3 0.0 6.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 KDO21763.1 - 2.8e-05 24.4 0.0 0.004 17.5 0.0 3.4 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO21763.1 - 0.0021 18.4 3.3 5.1 8.0 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KDO21763.1 - 0.057 13.2 1.8 0.97 9.3 0.0 3.7 3 2 0 3 3 3 0 Leucine rich repeat Spc7 PF08317.11 KDO21764.1 - 8.6e-05 21.6 6.9 8.6e-05 21.6 6.9 3.4 3 1 1 4 4 4 1 Spc7 kinetochore protein FKBP_C PF00254.28 KDO21764.1 - 0.00052 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF5082 PF16888.5 KDO21764.1 - 0.0015 18.8 1.8 0.0015 18.8 1.8 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF5082) HALZ PF02183.18 KDO21764.1 - 0.0086 16.3 0.7 0.0086 16.3 0.7 6.3 6 0 0 6 6 6 2 Homeobox associated leucine zipper Clathrin_lg_ch PF01086.17 KDO21765.1 - 3.8e-09 36.9 11.2 7.1e-08 32.8 11.2 2.0 1 1 0 1 1 1 1 Clathrin light chain DUF2605 PF10792.9 KDO21765.1 - 0.05 13.5 1.2 0.081 12.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) DUF4542 PF15075.6 KDO21766.1 - 0.059 13.7 0.1 0.081 13.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) APC_u15 PF16636.5 KDO21766.1 - 7.5 7.1 9.9 75 3.9 9.9 2.2 1 1 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 Ribosomal_S7e PF01251.18 KDO21767.1 - 3.4e-82 274.7 2.3 3.9e-82 274.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e UPF0060 PF02694.15 KDO21768.1 - 8.4e-31 106.4 10.9 9.5e-31 106.2 10.9 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 KDO21768.1 - 5.1e-06 26.7 9.2 4.9e-05 23.5 3.8 2.0 1 1 1 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 KDO21768.1 - 0.0037 17.9 4.7 0.0052 17.4 4.7 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein DUF1358 PF07096.11 KDO21768.1 - 0.11 12.5 3.2 0.14 12.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) OSTMP1 PF09777.9 KDO21769.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Adenylsucc_synt PF00709.21 KDO21770.1 - 3.3e-163 543.5 0.7 3.2e-96 322.8 0.0 2.1 1 1 1 2 2 2 2 Adenylosuccinate synthetase WW PF00397.26 KDO21770.1 - 0.0062 16.6 8.4 0.014 15.4 8.4 1.6 1 0 0 1 1 1 1 WW domain Siva PF05458.12 KDO21770.1 - 0.13 12.0 2.0 0.45 10.2 1.6 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) CEBP_ZZ PF16366.5 KDO21770.1 - 0.7 10.2 4.8 1.6 9.1 4.8 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KDO21770.1 - 1.1 9.4 7.5 2.2 8.5 7.5 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF4490 PF14892.6 KDO21771.1 - 0.0034 17.4 0.2 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4490) MCM PF00493.23 KDO21772.1 - 4.8e-74 248.2 0.0 7.9e-74 247.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KDO21772.1 - 8.2e-22 77.4 3.3 1.8e-21 76.3 3.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KDO21772.1 - 2.1e-16 60.1 4.6 4e-16 59.2 4.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KDO21772.1 - 8.2e-08 31.9 0.1 0.0003 20.2 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO21772.1 - 1.1e-06 28.7 0.0 3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KDO21772.1 - 0.032 14.1 0.0 0.13 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KDO21772.1 - 0.045 13.1 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KDO21772.1 - 0.066 13.6 0.1 0.16 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KDO21772.1 - 0.067 12.9 1.2 0.3 10.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KDO21772.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KDO21772.1 - 0.1 12.3 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 KDO21772.1 - 0.13 12.5 0.5 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KDO21772.1 - 0.17 12.3 0.3 1.8 8.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain SK_channel PF03530.14 KDO21773.1 - 1.2e-12 47.8 0.6 9.3e-12 45.0 0.9 2.2 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 KDO21773.1 - 1.4e-12 47.4 9.8 3.3e-11 43.0 9.2 2.4 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KDO21773.1 - 0.00011 21.5 8.6 0.00011 21.5 8.6 1.9 2 1 0 2 2 2 1 Ion transport protein DUF5056 PF16479.5 KDO21773.1 - 0.33 11.2 2.4 4.4 7.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) PKD_channel PF08016.12 KDO21774.1 - 7.4e-10 38.1 4.8 7.4e-10 38.1 4.8 2.5 2 1 0 3 3 3 1 Polycystin cation channel PKD_channel PF08016.12 KDO21775.1 - 4.4e-10 38.8 4.9 8.3e-10 37.9 4.2 1.6 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KDO21775.1 - 1.2e-08 34.5 10.0 3.1e-08 33.1 10.0 1.7 1 1 0 1 1 1 1 Ion transport protein Tmemb_185A PF10269.9 KDO21776.1 - 2.4e-08 34.0 15.2 1.8e-07 31.1 4.0 3.0 3 0 0 3 3 3 2 Transmembrane Fragile-X-F protein Tmemb_185A PF10269.9 KDO21777.1 - 1.6e-07 31.3 20.8 0.00048 19.9 0.4 3.2 1 1 1 3 3 3 2 Transmembrane Fragile-X-F protein Cytochrome-c551 PF10643.9 KDO21777.1 - 1 8.9 4.1 2.1 7.9 0.4 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 RsfS PF02410.15 KDO21778.1 - 4.3e-21 75.2 0.3 5.4e-21 74.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation FMN_red PF03358.15 KDO21780.1 - 4e-22 78.6 0.0 4.8e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO21780.1 - 0.00054 19.7 0.0 0.0007 19.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KDO21781.1 - 1.1e-23 83.7 0.0 1.5e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO21781.1 - 3.4e-05 23.6 0.0 4.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Gluconate_2-dh3 PF13618.6 KDO21781.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Nuc_sug_transp PF04142.15 KDO21782.1 - 7.1e-29 101.0 17.1 8.7e-29 100.7 17.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KDO21782.1 - 0.0029 17.8 26.6 0.18 12.0 5.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family Cytochrom_C_asm PF01578.20 KDO21782.1 - 0.26 11.0 17.3 0.12 12.2 7.7 2.9 2 1 1 3 3 3 0 Cytochrome C assembly protein DUF5379 PF17350.2 KDO21782.1 - 0.27 11.5 0.2 0.27 11.5 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5379) Phage_holin_1 PF04531.13 KDO21782.1 - 3.3 8.3 5.2 1.3 9.6 1.3 2.4 3 0 0 3 3 3 0 Bacteriophage holin Mito_carr PF00153.27 KDO21783.1 - 3.6e-66 219.2 3.4 1e-22 79.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0113_N PF17833.1 KDO21784.1 - 1e-26 93.3 0.2 1.7e-26 92.6 0.2 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KDO21784.1 - 8.4e-24 83.6 0.0 1.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain WYL_3 PF18488.1 KDO21784.1 - 0.12 12.7 0.2 5.8 7.4 0.1 2.4 2 0 0 2 2 2 0 WYL domain Ribosomal_S9 PF00380.19 KDO21785.1 - 1.5e-32 112.7 0.2 1.7e-32 112.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Fib_alpha PF08702.10 KDO21786.1 - 0.018 15.2 1.7 0.018 15.2 1.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KDO21786.1 - 0.64 9.3 4.8 1.1 8.5 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KDO21786.1 - 1.1 9.1 7.0 2.6 7.8 7.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 KDO21786.1 - 1.1 8.8 6.2 2.2 7.8 6.2 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MCC-bdg_PDZ PF10506.9 KDO21786.1 - 1.4 9.0 9.7 0.37 10.8 2.3 2.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF812 PF05667.11 KDO21786.1 - 2 7.2 13.9 0.071 12.0 6.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) PspB PF06667.12 KDO21786.1 - 2.5 8.2 6.8 3.3 7.8 2.1 2.5 1 1 1 2 2 2 0 Phage shock protein B Tropomyosin_1 PF12718.7 KDO21786.1 - 3.3 7.8 14.6 6.2 7.0 11.2 2.7 2 1 0 2 2 2 0 Tropomyosin like CTI PF06934.11 KDO21786.1 - 4.6 5.6 6.1 2.2 6.7 2.6 1.8 2 0 0 2 2 2 0 Fatty acid cis/trans isomerase (CTI) Ntox1 PF15500.6 KDO21787.1 - 0.023 15.1 3.1 0.14 12.5 0.1 2.2 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 SAB PF04382.13 KDO21787.1 - 0.023 14.7 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 SAB domain Zein-binding PF04576.15 KDO21787.1 - 0.065 13.5 1.3 0.065 13.5 1.3 2.4 3 0 0 3 3 3 0 Zein-binding Apolipoprotein PF01442.18 KDO21787.1 - 0.31 10.9 5.1 3.7 7.4 0.7 1.9 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Mst1_SARAH PF11629.8 KDO21787.1 - 2.7 8.2 8.4 0.14 12.3 1.9 2.1 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Tenui_N PF05733.11 KDO21788.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein Pkinase_Tyr PF07714.17 KDO21789.1 - 6.9e-56 189.4 0.0 7.9e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21789.1 - 2.3e-52 177.9 0.0 2.9e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO21789.1 - 0.00021 21.3 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO21789.1 - 0.00042 19.7 0.0 0.00062 19.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO21789.1 - 0.00054 19.0 0.0 0.0008 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO21789.1 - 0.028 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO21789.1 - 0.034 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Tower PF09121.10 KDO21791.1 - 0.19 11.9 0.1 0.36 11.1 0.1 1.4 1 0 0 1 1 1 0 Tower Perm-CXXC PF15629.6 KDO21791.1 - 2.2 8.6 13.1 1.6 9.1 1.2 3.6 4 0 0 4 4 4 0 Permuted single zf-CXXC unit DUF3586 PF12131.8 KDO21791.1 - 3.3 8.0 16.4 1.4 9.2 5.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3586) CxC6 PF18721.1 KDO21791.1 - 3.7 7.9 23.3 5.3 7.4 3.0 3.7 1 1 2 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases Glyco_transf_22 PF03901.17 KDO21792.1 - 3.6e-47 161.5 12.5 4.8e-47 161.1 12.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family UPF0172 PF03665.13 KDO21793.1 - 9.5e-36 123.6 0.0 1.1e-35 123.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Cep57_MT_bd PF06657.13 KDO21794.1 - 0.0046 17.4 0.3 0.01 16.2 0.2 1.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Med9 PF07544.13 KDO21794.1 - 0.0063 16.6 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 KDO21794.1 - 0.044 14.4 0.1 2.4 8.8 0.0 2.8 3 0 0 3 3 3 0 SlyX NuA4 PF09340.10 KDO21794.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 ABC_tran_CTD PF16326.5 KDO21794.1 - 0.74 10.1 5.1 0.33 11.2 0.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Aminotran_1_2 PF00155.21 KDO21795.1 - 7.6e-12 45.1 0.0 4e-10 39.4 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Ank_2 PF12796.7 KDO21796.1 - 1.3e-16 60.9 11.2 6.8e-10 39.4 2.3 3.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21796.1 - 5.9e-15 55.4 8.3 1.6e-08 34.9 1.5 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21796.1 - 1e-10 40.8 12.6 0.012 16.0 0.1 5.7 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KDO21796.1 - 1.2e-10 41.4 12.0 8.5e-06 25.9 1.1 4.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO21796.1 - 3.8e-10 39.7 23.3 0.00076 19.8 0.3 5.4 4 2 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KDO21797.1 - 5.6e-30 103.8 50.0 4.6e-07 30.3 0.3 7.4 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21797.1 - 2.7e-17 62.9 39.7 9.6e-06 26.0 1.6 10.8 7 4 2 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21797.1 - 1.6e-10 41.0 33.6 0.41 11.0 0.2 11.7 5 3 9 14 14 14 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21797.1 - 4.1e-09 35.9 33.2 11 7.0 0.0 13.5 15 0 0 15 15 15 4 Ankyrin repeat PA PF02225.22 KDO21797.1 - 0.038 14.0 0.6 0.2 11.7 0.4 2.3 2 0 0 2 2 2 0 PA domain ADH_zinc_N PF00107.26 KDO21797.1 - 0.066 13.2 1.0 12 5.8 0.0 3.5 3 2 0 3 3 3 0 Zinc-binding dehydrogenase Phage_int_SAM_1 PF02899.17 KDO21797.1 - 0.11 12.9 0.6 1.5 9.2 0.2 3.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Ank PF00023.30 KDO21797.1 - 6.7 7.3 37.1 19 5.9 0.1 11.1 6 2 3 9 9 9 0 Ankyrin repeat DHHC PF01529.20 KDO21798.1 - 6e-35 120.3 2.3 6e-35 120.3 2.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KDO21798.1 - 5.3e-18 65.4 5.4 8.6e-10 39.1 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO21798.1 - 8.4e-13 48.1 4.6 0.00099 19.5 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KDO21798.1 - 1.1e-12 48.1 0.5 0.0022 18.5 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21798.1 - 1.1e-10 41.6 1.3 9.2e-05 22.7 0.2 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21798.1 - 3.5e-07 30.0 0.3 0.51 11.1 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Fer4_2 PF12797.7 KDO21800.1 - 0.015 15.4 13.8 0.14 12.3 3.4 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 KDO21800.1 - 3.4 7.8 17.8 42 4.3 4.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KDO21801.1 - 5 7.4 18.6 11 6.4 3.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Pyr_redox_2 PF07992.14 KDO21802.1 - 4.6e-35 121.3 0.2 5.4e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO21802.1 - 2.3e-15 56.9 0.6 1.3e-08 35.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KDO21802.1 - 7.5e-08 31.9 1.4 0.12 11.5 0.1 2.9 1 1 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KDO21802.1 - 1.4e-07 31.1 0.0 9.1e-05 21.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO21802.1 - 3.3e-05 23.6 8.3 0.15 11.6 0.0 3.7 2 2 2 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO21802.1 - 5.5e-05 22.4 0.5 0.0098 15.0 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KDO21802.1 - 0.00033 20.7 6.0 0.035 14.1 0.0 4.0 2 2 2 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KDO21802.1 - 0.00061 20.0 0.8 0.22 11.8 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KDO21802.1 - 0.0014 18.0 0.1 0.028 13.8 0.0 2.1 2 0 0 2 2 2 1 ThiF family Thi4 PF01946.17 KDO21802.1 - 0.0014 17.9 1.7 0.36 10.0 0.2 2.4 2 0 0 2 2 2 2 Thi4 family TrkA_N PF02254.18 KDO21802.1 - 0.0021 18.3 0.2 2.1 8.6 0.1 2.7 3 0 0 3 3 2 2 TrkA-N domain Trp_halogenase PF04820.14 KDO21802.1 - 0.0032 16.4 1.5 0.23 10.2 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.6 KDO21802.1 - 0.021 15.2 1.5 6.9 7.2 0.6 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KDO21802.1 - 0.054 12.6 6.2 2.2 7.3 0.9 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 KDO21802.1 - 0.064 13.5 0.6 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HI0933_like PF03486.14 KDO21802.1 - 0.46 9.1 1.5 13 4.3 0.3 2.5 3 0 0 3 3 3 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KDO21802.1 - 1.6 8.2 3.4 23 4.5 0.0 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TIR_2 PF13676.6 KDO21803.1 - 2.5e-18 66.8 0.0 4.7e-12 46.6 0.0 2.6 2 0 0 2 2 2 2 TIR domain NACHT PF05729.12 KDO21803.1 - 2.3e-08 34.2 0.1 9.9e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 NACHT domain SH2 PF00017.24 KDO21803.1 - 6.8e-07 29.3 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain AAA_16 PF13191.6 KDO21803.1 - 1.5e-06 28.7 0.3 4.1e-06 27.3 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KDO21803.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KDO21803.1 - 0.033 14.5 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KDO21803.1 - 0.089 13.2 0.0 0.67 10.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MWFE PF15879.5 KDO21804.1 - 1.3e-05 25.2 11.5 0.0033 17.6 11.5 2.2 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit zf-CCHC PF00098.23 KDO21805.1 - 4.5e-41 137.1 59.3 2.8e-08 33.5 3.8 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.6 KDO21805.1 - 4.7e-18 64.7 52.1 9.7e-05 22.1 3.6 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 KDO21805.1 - 3.9e-10 39.3 35.1 0.0029 17.3 0.4 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 KDO21805.1 - 0.0072 16.3 36.4 0.71 9.9 0.5 6.0 1 1 5 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 KDO21805.1 - 0.024 14.3 2.3 0.024 14.3 2.3 6.1 6 0 0 6 6 6 0 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 KDO21805.1 - 0.037 13.8 0.4 0.037 13.8 0.4 6.0 6 0 0 6 6 6 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 KDO21805.1 - 1.2 9.1 46.8 0.08 12.8 3.6 5.9 4 1 2 6 6 6 0 Zinc knuckle zinc-ribbons_6 PF07191.12 KDO21805.1 - 6.7 6.8 28.1 1.9 8.5 8.5 3.6 1 1 2 3 3 3 0 zinc-ribbons DUF4558 PF15104.6 KDO21806.1 - 9.1e-20 70.5 5.2 1.2e-19 70.1 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) DUF2944 PF11161.8 KDO21809.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) ubiquitin PF00240.23 KDO21810.1 - 5.8e-05 22.8 0.1 7.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 KDO21810.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 UBX domain Phage_integrase PF00589.22 KDO21811.1 - 0.00029 20.7 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF3993 PF13158.6 KDO21812.1 - 0.085 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Cellulase PF00150.18 KDO21813.1 - 2.7e-32 112.4 0.0 3.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) THUMP PF02926.17 KDO21814.1 - 1.9e-18 67.0 3.4 3.2e-18 66.2 3.4 1.4 1 0 0 1 1 1 1 THUMP domain Utp13 PF08625.11 KDO21814.1 - 0.013 15.4 0.2 0.034 14.0 0.2 1.7 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Sigma70_ner PF04546.13 KDO21814.1 - 0.33 10.8 6.6 4.1 7.2 3.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.6 KDO21814.1 - 0.49 10.6 9.3 0.63 10.3 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 KDO21814.1 - 0.6 9.8 12.5 0.041 13.6 3.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KDO21814.1 - 4.1 6.6 9.1 0.78 9.0 2.1 2.4 2 0 0 2 2 2 0 NOA36 protein PBP1_TM PF14812.6 KDO21814.1 - 8.3 6.9 12.1 1 9.8 3.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UcrQ PF02939.16 KDO21815.1 - 1.3e-06 28.3 0.3 5.6e-05 23.0 0.3 2.4 1 1 1 2 2 2 1 UcrQ family DUF667 PF05018.13 KDO21816.1 - 4e-91 303.8 0.8 5.3e-91 303.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ysc84 PF04366.12 KDO21816.1 - 2.6e-32 111.3 0.3 4.2e-32 110.6 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator tRNA-synt_2b PF00587.25 KDO21817.1 - 8e-27 94.3 0.0 1.3e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KDO21817.1 - 2.7e-06 27.5 0.8 8.2e-06 26.0 0.8 1.8 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PEPCK_ATP PF01293.20 KDO21818.1 - 1.7e-204 679.8 0.2 6.9e-203 674.5 0.2 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ank_2 PF12796.7 KDO21819.1 - 4.1e-10 40.1 12.3 0.00077 20.0 0.9 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21819.1 - 4.6e-08 33.5 15.4 0.00022 21.7 0.1 6.4 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21819.1 - 3e-05 24.1 7.5 11 7.0 0.1 7.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KDO21819.1 - 0.0016 18.7 15.6 0.17 12.2 0.1 6.3 5 1 3 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO21819.1 - 0.89 10.1 9.0 23 5.7 0.1 5.4 3 1 0 3 3 3 0 Ankyrin repeat F-box-like_2 PF13013.6 KDO21820.1 - 0.084 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain Abhydrolase_1 PF00561.20 KDO21821.1 - 1.6e-24 86.9 0.0 4.7e-24 85.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO21821.1 - 1.3e-17 63.8 0.0 3.3e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 KDO21821.1 - 0.062 13.9 11.7 0.9 10.1 11.7 2.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO21821.1 - 0.096 11.9 0.0 3.8 6.7 0.1 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DUF4419 PF14388.6 KDO21822.1 - 2.5e-102 342.4 0.0 2.9e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TrbE PF11100.8 KDO21822.1 - 0.09 13.0 0.5 0.62 10.3 0.1 2.3 2 0 0 2 2 2 0 Conjugal transfer protein TrbE Abhydrolase_1 PF00561.20 KDO21823.1 - 1.9e-21 76.9 0.1 1.6e-17 64.0 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO21823.1 - 7.6e-16 58.1 0.0 3.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein DHBP_synthase PF00926.19 KDO21824.1 - 8.2e-83 276.6 0.0 1.1e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 KDO21824.1 - 0.039 13.5 0.0 8.8 5.9 0.0 2.4 1 1 1 2 2 2 0 GTP cyclohydrolase II Pyridoxal_deC PF00282.19 KDO21825.1 - 2.5e-20 72.6 0.0 4.3e-20 71.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SelA PF03841.13 KDO21825.1 - 0.0007 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_5 PF00266.19 KDO21825.1 - 0.056 12.4 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Thionin PF00321.17 KDO21826.1 - 0.16 12.5 0.5 0.16 12.5 0.5 1.9 2 1 0 2 2 2 0 Plant thionin Pkinase PF00069.25 KDO21827.1 - 9.6e-32 110.4 0.0 7.7e-30 104.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21827.1 - 1.4e-27 96.6 0.0 8.2e-26 90.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Adeno_E3_CR2 PF02439.15 KDO21827.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KDO21827.1 - 0.18 11.3 4.3 0.45 10.0 4.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GRP PF07172.11 KDO21827.1 - 0.94 10.2 21.0 2.1 9.1 21.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family LRR_8 PF13855.6 KDO21827.1 - 1.2 8.9 8.4 1.5 8.6 3.7 3.1 2 1 1 3 3 3 0 Leucine rich repeat Pkinase_Tyr PF07714.17 KDO21828.1 - 3.6e-45 154.3 0.0 5.2e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21828.1 - 4.3e-44 150.9 0.0 6.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.15 KDO21828.1 - 0.0092 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KDO21828.1 - 0.023 14.1 4.3 0.044 13.2 4.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GRA6 PF05084.13 KDO21828.1 - 0.11 12.4 0.4 0.21 11.5 0.4 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Podoplanin PF05808.11 KDO21828.1 - 0.14 12.3 5.0 0.085 13.0 0.4 2.7 3 0 0 3 3 3 0 Podoplanin CwsA PF10814.8 KDO21828.1 - 0.16 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Pkinase_Tyr PF07714.17 KDO21829.1 - 4.5e-42 144.1 0.0 6.3e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21829.1 - 2.2e-41 142.0 0.0 3.4e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.15 KDO21829.1 - 0.0064 16.2 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KDO21829.1 - 0.0073 15.7 3.3 0.013 14.9 3.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 KDO21829.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.6 KDO21829.1 - 0.049 13.7 0.7 0.27 11.3 0.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) GRA6 PF05084.13 KDO21829.1 - 0.081 12.9 0.8 0.16 11.9 0.8 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) EphA2_TM PF14575.6 KDO21829.1 - 0.094 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KDO21829.1 - 0.12 12.2 0.5 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Beta-APP PF03494.13 KDO21829.1 - 0.25 11.2 5.7 0.5 10.3 5.7 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) LRR_4 PF12799.7 KDO21829.1 - 1.6 9.2 14.9 1.5 9.3 1.1 3.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21829.1 - 4.9 7.0 11.0 2.7 7.8 3.8 3.6 2 1 2 4 4 4 0 Leucine rich repeat tRNA-synt_1 PF00133.22 KDO21830.1 - 2.7e-140 468.5 0.0 6.3e-106 355.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KDO21830.1 - 3.5e-23 82.2 0.1 5.9e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KDO21830.1 - 3.6e-17 62.2 0.1 2.2e-08 33.3 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KDO21830.1 - 1.3e-05 24.7 0.0 0.0053 16.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KDO21830.1 - 3.7e-05 23.5 1.1 8.5e-05 22.3 1.1 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Pilin_PilA PF14245.6 KDO21830.1 - 0.024 14.6 0.0 0.077 13.0 0.0 1.8 2 0 0 2 2 2 0 Type IV pilin PilA tRNA-synt_1f PF01921.18 KDO21830.1 - 0.058 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Abhydrolase_3 PF07859.13 KDO21831.1 - 3.3e-22 79.4 0.4 5.5e-22 78.7 0.4 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KDO21831.1 - 2.7e-16 59.4 0.0 4.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Far-17a_AIG1 PF04750.14 KDO21832.1 - 0.011 15.0 15.4 0.021 14.2 15.2 1.6 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein DUF2433 PF10360.9 KDO21832.1 - 0.27 11.4 1.2 0.59 10.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) Far-17a_AIG1 PF04750.14 KDO21833.1 - 0.00017 21.0 14.1 0.00046 19.6 14.1 1.8 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.14 KDO21834.1 - 6.2e-07 28.9 8.7 6.2e-07 28.9 8.7 1.7 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein COG6 PF06419.11 KDO21835.1 - 5e-07 28.3 0.1 6e-07 28.1 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF3450 PF11932.8 KDO21835.1 - 0.057 12.7 0.3 0.077 12.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) PRKCSH-like PF12999.7 KDO21836.1 - 3.8e-06 26.8 1.6 4.7e-06 26.5 1.4 1.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like COPIIcoated_ERV PF07970.12 KDO21836.1 - 0.12 12.2 1.0 0.12 12.2 1.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter Tyrosinase PF00264.20 KDO21837.1 - 9e-11 42.5 0.3 1.9e-09 38.2 0.3 2.3 1 1 1 2 2 2 1 Common central domain of tyrosinase ZirS_C PF16583.5 KDO21837.1 - 0.045 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Pkinase PF00069.25 KDO21839.1 - 1e-48 166.0 0.0 1.4e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21839.1 - 1.2e-46 159.1 0.0 1.6e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO21839.1 - 0.00075 18.4 0.0 0.00092 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO21839.1 - 0.0082 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Tyrosinase PF00264.20 KDO21841.1 - 1.4e-24 87.7 0.1 8.2e-24 85.1 0.1 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase Ank PF00023.30 KDO21843.1 - 9.9e-16 57.4 1.8 7.8e-06 26.1 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KDO21843.1 - 1.8e-13 50.7 0.3 1e-10 41.9 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21843.1 - 7.7e-13 48.4 3.5 9.1e-07 29.0 0.8 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO21843.1 - 8.1e-13 48.8 4.7 1.7e-07 31.7 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO21843.1 - 3.6e-11 42.3 1.5 0.0017 18.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat SAM_2 PF07647.17 KDO21843.1 - 9.2e-10 38.5 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO21843.1 - 1.5e-08 35.0 0.0 2.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AF-4 PF05110.13 KDO21843.1 - 5.8 4.9 12.0 7.3 4.5 12.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sec20 PF03908.13 KDO21844.1 - 1.1e-06 28.5 1.5 1.2e-05 25.1 1.4 2.2 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.8 KDO21844.1 - 6.8e-06 26.3 2.9 1.4e-05 25.3 2.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF4407 PF14362.6 KDO21844.1 - 0.0058 16.0 1.3 0.0082 15.5 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2529 PF10740.9 KDO21844.1 - 0.013 15.1 0.3 0.022 14.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) FliMN_C PF01052.20 KDO21844.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term Babuvirus_MP PF07234.11 KDO21844.1 - 0.25 11.5 1.6 22 5.3 0.1 2.7 2 1 1 3 3 3 0 Movement and RNA silencing protein CopK PF11525.8 KDO21844.1 - 1.1 9.0 6.3 19 4.9 1.3 3.3 2 1 1 3 3 3 0 Copper resistance protein K Tim17 PF02466.19 KDO21846.1 - 3.8e-29 101.3 3.4 4.9e-29 101.0 3.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dus PF01207.17 KDO21847.1 - 2.4e-65 220.7 0.2 3e-65 220.4 0.2 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KDO21847.1 - 0.00013 21.6 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 KDO21847.1 - 0.0011 18.4 0.8 0.0023 17.3 0.8 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 KDO21847.1 - 0.003 17.0 0.7 0.0048 16.3 0.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Pet100 PF09803.9 KDO21848.1 - 8.1e-10 39.1 0.7 8.4e-10 39.0 0.7 1.0 1 0 0 1 1 1 1 Pet100 RNA_pol_Rpb8 PF03870.15 KDO21849.1 - 3.6e-46 156.8 0.0 4.1e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KDO21849.1 - 0.013 15.5 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G DUF1764 PF08576.10 KDO21850.1 - 1.3e-21 77.4 2.0 1.3e-21 77.4 2.0 2.1 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Dynactin_p62 PF05502.13 KDO21850.1 - 0.089 11.6 7.0 0.11 11.3 7.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family CDC27 PF09507.10 KDO21850.1 - 0.3 10.4 25.0 0.36 10.2 25.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PDCD2_C PF04194.13 KDO21850.1 - 0.85 9.7 13.8 23 5.0 13.8 2.1 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Tli4_N PF18443.1 KDO21850.1 - 1.3 9.3 6.4 0.29 11.5 0.2 2.2 1 1 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain MRP-S31 PF15433.6 KDO21850.1 - 1.4 8.6 15.1 2 8.0 15.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ank_2 PF12796.7 KDO21851.1 - 2.3e-41 140.3 12.8 1.2e-15 57.9 0.1 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21851.1 - 5e-26 90.7 2.8 2.2e-09 37.6 0.0 6.3 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21851.1 - 2.3e-23 79.7 4.5 0.00049 20.3 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KDO21851.1 - 1.2e-17 63.8 7.9 9.6e-05 22.6 0.6 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO21851.1 - 1.8e-14 53.4 14.3 0.00044 20.6 0.1 6.5 6 1 0 6 6 6 4 Ankyrin repeat EccE PF11203.8 KDO21851.1 - 0.047 14.0 3.7 3.2 8.1 0.3 3.2 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE DAGK_cat PF00781.24 KDO21853.1 - 4.3e-28 97.5 0.0 7.1e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KDO21853.1 - 0.083 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 ATP-NAD kinase PFK PF00365.20 KDO21853.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase Thioredoxin PF00085.20 KDO21855.1 - 4.5e-08 33.0 0.0 8.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KDO21855.1 - 0.0015 17.6 0.1 0.0016 17.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin IL28A PF15177.6 KDO21855.1 - 0.059 13.2 3.5 0.25 11.2 1.2 2.1 2 0 0 2 2 2 0 Interleukin-28A YlqD PF11068.8 KDO21855.1 - 0.3 11.5 6.6 0.46 10.9 6.6 1.3 1 0 0 1 1 1 0 YlqD protein DctP PF03480.13 KDO21855.1 - 0.4 10.0 3.5 0.59 9.4 3.5 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 FerA PF08165.11 KDO21855.1 - 1.3 9.0 7.3 2.5 8.1 5.3 2.3 2 1 0 2 2 2 0 FerA (NUC095) domain E2F_CC-MB PF16421.5 KDO21855.1 - 1.3 9.4 5.5 39 4.7 4.9 2.5 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain PP28 PF10252.9 KDO21856.1 - 8.7e-20 71.0 18.0 8.7e-20 71.0 18.0 3.0 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.27 KDO21856.1 - 2.2e-09 36.9 0.4 5.4e-09 35.6 0.4 1.7 1 0 0 1 1 1 1 SAP domain DUF2849 PF11011.8 KDO21856.1 - 0.039 14.6 2.5 0.039 14.6 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2849) GST_C_5 PF16865.5 KDO21857.1 - 2.1e-08 34.7 0.0 4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO21857.1 - 3.8e-08 33.6 0.0 1.4e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO21857.1 - 1.8e-07 31.1 0.3 3e-07 30.4 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO21857.1 - 1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO21857.1 - 2.4e-05 24.6 0.0 4.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO21857.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KDO21858.1 - 2.4e-08 34.5 0.1 4.2e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO21858.1 - 3.4e-08 33.8 0.0 6.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO21858.1 - 1.8e-06 28.2 0.0 3.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO21858.1 - 2.4e-06 27.5 0.4 7.3e-06 25.9 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO21858.1 - 5.7e-06 26.6 0.0 1.6e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO21858.1 - 0.00013 22.1 0.1 0.00027 21.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO21858.1 - 0.0019 18.4 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KDO21858.1 - 0.049 14.4 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Lactamase_B PF00753.27 KDO21859.1 - 1.2e-08 35.3 1.7 1.2e-07 32.0 1.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Sulfotransfer_3 PF13469.6 KDO21859.1 - 0.03 14.7 0.0 0.092 13.1 0.0 1.8 2 0 0 2 2 2 0 Sulfotransferase family Lactamase_B PF00753.27 KDO21860.1 - 2.3e-05 24.5 0.7 2.7e-05 24.3 0.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Sulfotransfer_3 PF13469.6 KDO21860.1 - 0.043 14.2 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family Nucleoside_tran PF01733.18 KDO21861.1 - 6.5e-17 61.9 7.2 6.5e-17 61.9 7.2 2.5 2 1 1 3 3 3 2 Nucleoside transporter DUF2198 PF09964.9 KDO21861.1 - 5.4 7.2 10.2 5.1 7.3 2.3 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) GST_C_5 PF16865.5 KDO21862.1 - 7.3e-13 49.0 0.1 3.2e-12 47.0 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO21862.1 - 2.9e-11 43.6 0.0 6.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO21862.1 - 3.2e-10 40.2 0.0 9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO21862.1 - 4.3e-09 36.5 0.0 7.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO21862.1 - 2.3e-06 27.5 0.2 4.1e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO21862.1 - 3.6e-05 23.9 0.4 9e-05 22.6 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO21862.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KDO21862.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C_5 PF16865.5 KDO21863.1 - 8.1e-12 45.7 0.0 2.2e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO21863.1 - 3.1e-10 40.3 0.0 7.6e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO21863.1 - 1.5e-09 37.7 0.3 2.8e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO21863.1 - 8.4e-09 35.7 0.0 2.9e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO21863.1 - 5e-07 29.9 0.0 9.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO21863.1 - 3.3e-06 27.2 0.1 6.1e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO21863.1 - 0.0024 18.1 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KDO21864.1 - 7.2e-14 52.3 0.1 1.5e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO21864.1 - 6e-08 32.9 0.0 1.7e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO21864.1 - 6.9e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO21864.1 - 2.9e-07 30.4 0.2 5.7e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO21864.1 - 8.7e-07 29.2 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO21864.1 - 2.3e-05 24.5 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO21864.1 - 0.034 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HMGL-like PF00682.19 KDO21866.1 - 2e-66 224.2 0.3 1.5e-27 96.8 0.3 3.3 1 1 2 3 3 3 3 HMGL-like LeuA_dimer PF08502.10 KDO21866.1 - 8.1e-34 116.4 0.7 1.4e-33 115.6 0.7 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain GCD14 PF08704.10 KDO21866.1 - 0.1 12.3 0.1 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit EamA PF00892.20 KDO21868.1 - 0.032 14.4 45.9 0.54 10.4 13.7 3.8 3 1 0 3 3 3 0 EamA-like transporter family DUF4153 PF13687.6 KDO21868.1 - 0.56 9.8 12.7 0.51 9.9 4.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) LRR_4 PF12799.7 KDO21870.1 - 0.0002 21.7 0.3 0.23 11.9 0.1 3.6 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO21870.1 - 0.00055 19.8 8.1 0.18 11.9 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 KDO21870.1 - 0.14 12.0 2.4 2 8.2 0.5 3.5 2 1 0 2 2 2 0 Leucine rich repeat VWA_2 PF13519.6 KDO21871.1 - 4e-07 30.7 0.0 1.8e-06 28.5 0.0 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.19 KDO21871.1 - 7.9e-06 25.3 0.0 6.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain VWA PF00092.28 KDO21871.1 - 6.2e-05 23.3 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KDO21871.1 - 0.00016 20.0 0.1 0.00026 19.3 0.1 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 KDO21871.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family LRR_6 PF13516.6 KDO21872.1 - 0.00014 21.6 12.2 0.029 14.4 0.1 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 KDO21872.1 - 0.0012 19.2 4.3 0.057 13.9 0.3 3.5 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO21872.1 - 0.064 13.0 3.2 2.1 8.2 2.2 3.3 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 KDO21872.1 - 0.27 11.9 2.9 66 4.6 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 KDO21873.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase ABC_membrane PF00664.23 KDO21874.1 - 2.1e-51 175.2 27.3 1.9e-34 119.6 14.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO21874.1 - 2.8e-48 163.9 0.0 4.5e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO21874.1 - 3.9e-11 42.8 4.4 0.012 15.0 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO21874.1 - 3.6e-06 27.0 0.3 0.022 14.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO21874.1 - 1.5e-05 25.4 0.1 0.18 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KDO21874.1 - 2.3e-05 24.7 0.1 0.23 11.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KDO21874.1 - 3.5e-05 23.8 0.1 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO21874.1 - 4.9e-05 23.0 2.5 0.3 10.8 0.3 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO21874.1 - 0.00036 20.2 0.6 0.16 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KDO21874.1 - 0.00065 19.6 0.5 0.99 9.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KDO21874.1 - 0.0011 19.0 1.8 0.097 12.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 KDO21874.1 - 0.002 17.7 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KDO21874.1 - 0.0024 18.0 4.1 0.02 15.0 0.5 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 KDO21874.1 - 0.0026 17.4 0.4 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KDO21874.1 - 0.0085 16.6 0.9 5.2 7.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KDO21874.1 - 0.014 15.4 0.0 14 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KDO21874.1 - 0.018 14.7 0.0 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 KDO21874.1 - 0.024 14.6 0.1 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 KDO21874.1 - 0.031 14.1 3.3 2.3 7.9 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 KDO21874.1 - 0.04 13.3 1.5 2.4 7.4 0.1 2.6 2 0 0 2 2 2 0 AIG1 family AAA_33 PF13671.6 KDO21874.1 - 0.047 13.9 0.4 6.2 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KDO21874.1 - 0.055 13.7 0.3 13 6.1 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KDO21874.1 - 0.063 12.4 3.9 8.8 5.4 0.0 3.0 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KDO21874.1 - 0.065 13.0 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO21874.1 - 0.082 12.2 0.5 4.1 6.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 KDO21874.1 - 0.11 11.6 0.2 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KDO21874.1 - 0.13 11.9 1.0 7.4 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KDO21874.1 - 0.14 12.5 0.1 26 5.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_PrkA PF08298.11 KDO21874.1 - 0.2 10.5 0.7 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 PrkA AAA domain Zeta_toxin PF06414.12 KDO21874.1 - 4.5 6.5 4.6 19 4.5 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin GST_C_3 PF14497.6 KDO21875.1 - 5.9e-09 36.0 0.0 8.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO21875.1 - 4e-06 27.1 0.0 8.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO21875.1 - 6.5e-06 26.1 1.5 1.2e-05 25.2 1.5 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO21875.1 - 0.0015 18.7 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_6 PF00970.24 KDO21876.1 - 0.0075 16.6 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 KDO21876.1 - 0.036 14.6 0.2 0.097 13.2 0.2 1.8 1 1 0 1 1 1 0 Globin Globin PF00042.22 KDO21877.1 - 2.9e-05 24.6 0.2 9.6e-05 22.9 0.2 1.9 1 1 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KDO21877.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Mg_trans_NIPA PF05653.14 KDO21878.1 - 1.7e-16 60.2 6.5 2.4e-16 59.7 6.5 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA Thioredoxin PF00085.20 KDO21879.1 - 4.9e-28 97.1 0.0 6.2e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO21879.1 - 3.4e-05 24.3 0.0 0.00082 19.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO21879.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO21879.1 - 0.00049 20.4 0.0 0.00081 19.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KDO21879.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KDO21879.1 - 0.0078 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KDO21879.1 - 0.0082 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KDO21879.1 - 0.014 15.1 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 KDO21879.1 - 0.11 12.7 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.20 KDO21880.1 - 1.3e-24 86.1 0.0 1.4e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO21880.1 - 1.2e-06 28.9 0.0 3.8e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO21880.1 - 4.1e-05 23.7 0.0 7.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO21880.1 - 0.0013 19.1 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KDO21880.1 - 0.0022 17.4 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KDO21880.1 - 0.0032 17.3 0.0 0.004 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KDO21880.1 - 0.033 13.9 0.1 0.057 13.1 0.1 1.4 1 1 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 KDO21880.1 - 0.036 14.0 0.1 0.062 13.2 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 KDO21880.1 - 0.075 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin ARPC4 PF05856.12 KDO21882.1 - 7.1e-80 266.5 4.0 7.9e-80 266.3 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Cyt-b5 PF00173.28 KDO21883.1 - 2.7e-05 24.2 0.0 4.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.26 KDO21884.1 - 0.0083 16.5 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 FHA domain RsfS PF02410.15 KDO21885.1 - 1.5e-20 73.4 0.4 4.7e-20 71.9 0.4 1.8 1 1 1 2 2 2 1 Ribosomal silencing factor during starvation Myc_N PF01056.18 KDO21885.1 - 0.0024 17.8 0.5 0.0055 16.6 0.6 1.5 2 0 0 2 2 2 1 Myc amino-terminal region DUF2457 PF10446.9 KDO21885.1 - 0.13 11.4 12.6 0.2 10.7 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 KDO21885.1 - 0.54 10.1 6.5 1 9.2 6.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 KDO21885.1 - 0.91 7.5 2.7 1.3 7.0 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KDO21885.1 - 0.93 8.8 14.3 1.8 7.8 14.3 1.4 1 0 0 1 1 1 0 NOA36 protein BIRC6 PF12356.8 KDO21885.1 - 1.2 8.5 4.2 2.4 7.6 4.2 1.4 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 DNA_pol_phi PF04931.13 KDO21885.1 - 1.3 7.0 14.0 2 6.4 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KDO21885.1 - 2.3 7.9 16.6 4.8 6.8 16.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KDO21885.1 - 3.2 5.8 8.7 4.6 5.3 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family DNApol_Exo PF18136.1 KDO21886.1 - 0.033 13.4 0.0 0.091 11.9 0.0 1.6 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain FMN_red PF03358.15 KDO21887.1 - 8.3e-23 80.8 0.0 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO21887.1 - 0.00022 21.0 0.0 0.00028 20.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KDO21888.1 - 3.6e-23 82.0 0.0 4.6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO21888.1 - 0.00014 21.6 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Gluconate_2-dh3 PF13618.6 KDO21888.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.6 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Nuc_sug_transp PF04142.15 KDO21889.1 - 5.9e-29 101.2 17.9 7.3e-29 100.9 17.9 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KDO21889.1 - 0.001 19.2 27.9 0.06 13.5 6.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF5379 PF17350.2 KDO21889.1 - 0.26 11.6 0.2 0.26 11.6 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5379) Cytochrom_C_asm PF01578.20 KDO21889.1 - 0.33 10.7 17.6 0.12 12.2 7.7 3.0 2 1 0 3 3 3 0 Cytochrome C assembly protein Phage_holin_1 PF04531.13 KDO21889.1 - 4.2 8.0 5.9 1.3 9.6 1.3 2.5 3 0 0 3 3 3 0 Bacteriophage holin Mito_carr PF00153.27 KDO21890.1 - 3.4e-66 219.2 3.4 1e-22 79.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S9 PF00380.19 KDO21891.1 - 1.5e-32 112.7 0.2 1.7e-32 112.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Fib_alpha PF08702.10 KDO21892.1 - 0.014 15.6 1.7 0.014 15.6 1.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KDO21892.1 - 0.35 10.7 6.0 0.92 9.3 6.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 KDO21892.1 - 0.41 10.2 5.8 0.91 9.1 5.8 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 KDO21892.1 - 0.45 9.8 5.2 0.8 9.0 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCC-bdg_PDZ PF10506.9 KDO21892.1 - 0.51 10.4 8.8 0.17 11.9 1.4 3.0 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF812 PF05667.11 KDO21892.1 - 0.83 8.5 12.5 0.064 12.1 6.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) PspB PF06667.12 KDO21892.1 - 1.7 8.8 6.8 2.7 8.1 2.1 2.6 1 1 1 2 2 2 0 Phage shock protein B DUF1664 PF07889.12 KDO21892.1 - 1.7 8.7 3.8 1.5 8.9 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CTI PF06934.11 KDO21892.1 - 2.7 6.4 6.9 1.4 7.3 3.3 1.9 2 0 0 2 2 2 0 Fatty acid cis/trans isomerase (CTI) Ntox1 PF15500.6 KDO21893.1 - 0.017 15.5 2.8 0.13 12.6 0.1 2.2 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 SAB PF04382.13 KDO21893.1 - 0.022 14.8 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 SAB domain Zein-binding PF04576.15 KDO21893.1 - 0.045 14.0 0.9 0.045 14.0 0.9 2.4 3 0 0 3 3 3 0 Zein-binding Apolipoprotein PF01442.18 KDO21893.1 - 0.24 11.3 5.0 3.2 7.6 0.6 1.9 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Mst1_SARAH PF11629.8 KDO21893.1 - 2 8.6 8.1 0.13 12.4 1.9 2.1 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Pkinase_Tyr PF07714.17 KDO21896.1 - 1e-54 185.6 0.0 1.3e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21896.1 - 2.1e-51 174.8 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EGF_2 PF07974.13 KDO21896.1 - 0.00044 20.6 10.2 0.00044 20.6 10.2 15.4 6 3 6 12 12 12 6 EGF-like domain Kinase-like PF14531.6 KDO21896.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO21896.1 - 0.0024 16.9 0.0 0.0036 16.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO21896.1 - 0.0058 16.6 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO21896.1 - 0.061 12.1 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KDO21896.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EGF PF00008.27 KDO21896.1 - 0.14 12.4 166.5 0.023 15.0 10.0 12.3 12 0 0 12 12 12 0 EGF-like domain CxC6 PF18721.1 KDO21897.1 - 3.2 8.1 23.4 3.6 7.9 3.1 3.6 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases DUF3586 PF12131.8 KDO21897.1 - 3.5 7.9 16.4 1.7 9.0 5.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3586) Perm-CXXC PF15629.6 KDO21897.1 - 6.9 7.0 9.6 3.3 8.0 1.7 3.5 3 0 0 3 3 3 0 Permuted single zf-CXXC unit Pkinase PF00069.25 KDO21902.1 - 6e-59 199.6 0.0 7.4e-31 107.5 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Ank_2 PF12796.7 KDO21902.1 - 1.6e-47 160.0 13.8 5.3e-13 49.4 0.2 5.7 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KDO21902.1 - 1.2e-46 159.1 0.0 5e-24 85.0 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Ank_3 PF13606.6 KDO21902.1 - 1e-38 126.9 16.6 0.0001 22.4 0.0 12.3 11 1 1 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 KDO21902.1 - 1.1e-38 131.1 8.5 1.3e-07 32.1 0.0 8.2 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21902.1 - 1.5e-35 120.8 14.5 2.4e-08 34.1 0.1 8.9 4 4 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KDO21902.1 - 1.9e-23 81.8 27.8 0.0015 18.9 0.0 10.1 9 1 2 11 11 10 6 Ankyrin repeat Kinase-like PF14531.6 KDO21902.1 - 1.5e-07 31.0 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO21902.1 - 2.6e-07 29.8 0.0 0.0056 15.5 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 KDO21902.1 - 8e-06 25.4 0.9 0.12 11.8 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO21902.1 - 0.00012 21.2 0.1 0.046 12.6 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO21902.1 - 0.00043 19.4 0.1 0.78 8.7 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 APH PF01636.23 KDO21902.1 - 0.00084 19.3 0.7 0.51 10.2 0.1 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family FCD PF07729.12 KDO21902.1 - 0.031 14.7 0.5 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 FCD domain FliT PF05400.13 KDO21902.1 - 0.076 13.8 1.7 0.26 12.1 1.2 2.2 1 1 1 2 2 2 0 Flagellar protein FliT Pox_ser-thr_kin PF05445.11 KDO21902.1 - 0.13 11.2 0.2 11 4.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-NADH-PPase PF09297.11 KDO21903.1 - 0.02 14.6 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KDO21903.1 - 0.032 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf_C2H2_13 PF18508.1 KDO21903.1 - 0.033 13.8 0.0 0.099 12.3 0.0 1.8 2 0 0 2 2 2 0 Zinc finger domain zf-ribbon_3 PF13248.6 KDO21903.1 - 0.24 10.9 1.6 0.57 9.7 1.6 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Ank_2 PF12796.7 KDO21904.1 - 4.3e-07 30.4 0.8 1.4e-06 28.8 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21904.1 - 3e-05 24.5 0.6 0.00022 21.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21904.1 - 3.5e-05 23.9 0.8 0.022 15.3 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KDO21904.1 - 3.8e-05 23.9 5.0 0.0095 16.2 0.1 3.4 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO21904.1 - 0.0062 15.9 1.6 0.075 12.4 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21904.1 - 0.023 14.0 0.0 0.11 11.8 0.0 1.9 1 1 1 2 2 2 0 Protein tyrosine kinase DZR PF12773.7 KDO21904.1 - 0.033 14.2 9.9 0.68 10.0 2.5 2.7 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KDO21904.1 - 3.9 7.5 10.6 6.1e+02 0.5 10.6 2.6 1 1 0 1 1 1 0 zinc-ribbons Ank_2 PF12796.7 KDO21905.1 - 3.2e-89 293.6 71.8 5.1e-14 52.6 0.5 9.7 4 2 6 11 11 11 11 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO21905.1 - 2e-83 279.8 0.0 1.1e-41 143.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21905.1 - 1.1e-81 274.0 0.0 5.6e-42 143.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_4 PF13637.6 KDO21905.1 - 8.8e-65 214.3 32.0 1.3e-06 28.8 0.2 15.5 9 7 7 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21905.1 - 3.7e-59 189.7 39.9 0.00011 22.3 0.0 20.5 19 1 1 20 20 20 10 Ankyrin repeat Ank_5 PF13857.6 KDO21905.1 - 3.8e-45 151.4 67.6 8.4e-05 22.8 0.1 19.0 7 3 13 20 20 20 16 Ankyrin repeats (many copies) Ank PF00023.30 KDO21905.1 - 7.2e-40 133.7 75.3 0.00018 21.8 0.0 19.0 17 2 1 18 18 18 10 Ankyrin repeat Pkinase_fungal PF17667.1 KDO21905.1 - 1.3e-07 30.8 0.0 0.0081 15.0 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 KDO21905.1 - 4.7e-07 29.4 0.0 0.006 15.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO21905.1 - 4.4e-06 26.2 0.1 0.056 12.8 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO21905.1 - 2.5e-05 24.3 0.3 0.064 13.2 0.0 3.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KDO21905.1 - 0.0025 17.5 0.0 1.9 8.0 0.0 3.8 4 0 0 4 4 4 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO21905.1 - 0.0034 16.4 0.1 0.27 10.1 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain AnkUBD PF18418.1 KDO21905.1 - 0.014 15.6 0.8 4 7.7 0.0 4.0 4 0 0 4 4 3 0 Ankyrin ubiquitin-binding domain Choline_kinase PF01633.20 KDO21905.1 - 0.068 12.7 0.0 14 5.2 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF5475 PF17569.2 KDO21905.1 - 0.14 12.5 0.0 0.63 10.4 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5475) Ank_2 PF12796.7 KDO21909.1 - 1.5e-97 320.3 39.1 1.5e-14 54.3 0.1 13.0 6 3 6 13 13 13 13 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO21909.1 - 2.3e-96 322.2 0.0 2.4e-43 148.4 0.0 4.3 3 2 1 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21909.1 - 1.1e-91 306.8 0.0 1.5e-40 139.1 0.0 4.1 3 1 1 4 4 4 3 Protein tyrosine kinase Ank_4 PF13637.6 KDO21909.1 - 7.9e-81 265.5 32.1 2.3e-10 40.8 0.0 16.4 10 5 6 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21909.1 - 4.1e-65 215.0 52.9 1e-06 28.9 0.0 19.6 8 4 14 22 22 21 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO21909.1 - 2.2e-61 196.6 45.1 0.00081 19.7 0.0 23.4 25 0 0 25 25 22 14 Ankyrin repeat Ank PF00023.30 KDO21909.1 - 3.6e-47 156.8 78.0 0.001 19.4 0.4 24.2 23 2 2 25 25 24 13 Ankyrin repeat Pkinase_fungal PF17667.1 KDO21909.1 - 1.4e-07 30.6 0.0 0.00048 19.0 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 KDO21909.1 - 1.8e-05 24.2 0.0 0.072 12.4 0.0 3.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KDO21909.1 - 2.8e-05 23.6 1.1 0.12 11.7 0.0 3.3 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO21909.1 - 3.8e-05 22.8 0.1 0.0049 15.8 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KDO21909.1 - 4.8e-05 23.4 1.4 1.4 8.7 0.1 4.4 4 0 0 4 4 4 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO21909.1 - 0.0013 17.8 1.5 1.5 7.7 0.0 2.9 3 0 0 3 3 3 2 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KDO21909.1 - 0.032 13.3 3.2 2.8 6.9 0.0 3.6 4 0 0 4 4 4 0 Seadornavirus VP7 RVP PF00077.20 KDO21909.1 - 0.66 10.3 2.0 8.9 6.7 0.0 3.9 6 0 0 6 6 4 0 Retroviral aspartyl protease NOB1_Zn_bind PF08772.11 KDO21909.1 - 2.9 8.1 7.5 5.9 7.1 1.0 2.7 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_4 PF14570.6 KDO21913.1 - 0.042 13.6 1.2 0.053 13.3 1.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 KDO21914.1 - 1e-52 179.1 0.0 3e-40 138.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21914.1 - 2e-47 161.6 0.0 6.5e-35 120.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO21914.1 - 7.9e-06 25.4 0.0 0.0065 15.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO21914.1 - 1.3e-05 24.7 0.1 0.025 13.9 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO21914.1 - 0.00031 19.6 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO21914.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO21914.1 - 0.0021 18.1 3.3 0.58 10.0 0.1 3.4 2 2 1 3 3 3 1 Phosphotransferase enzyme family Ank_5 PF13857.6 KDO21914.1 - 0.0076 16.5 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO21914.1 - 0.025 15.2 0.1 3.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KDO21915.1 - 1.1e-35 122.0 31.6 9.9e-14 51.7 5.9 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.25 KDO21915.1 - 6e-32 111.0 0.0 5.9e-30 104.5 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21915.1 - 9.5e-26 90.6 0.0 1e-23 84.0 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Ank PF00023.30 KDO21915.1 - 1.9e-23 81.8 19.7 1.2e-06 28.7 1.3 7.6 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KDO21915.1 - 9.9e-21 71.6 11.4 0.00055 20.2 0.3 7.1 8 0 0 8 8 7 5 Ankyrin repeat Ank_4 PF13637.6 KDO21915.1 - 1.4e-20 73.3 8.9 7e-06 26.5 0.3 5.8 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21915.1 - 5.2e-16 58.5 16.1 1.7e-09 37.8 2.1 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 KDO21915.1 - 0.00088 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO21915.1 - 0.0036 16.7 0.0 0.0075 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1697 PF08002.11 KDO21915.1 - 0.037 14.5 0.9 2.4 8.6 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1697) Haspin_kinase PF12330.8 KDO21915.1 - 0.049 12.6 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KDO21915.1 - 0.058 12.7 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO21915.1 - 0.083 12.8 0.7 0.41 10.5 0.2 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO21916.1 - 1.5e-73 247.4 0.0 1.6e-44 152.3 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21916.1 - 2.1e-63 214.1 0.0 1.9e-40 138.8 0.0 3.2 2 1 1 3 3 3 2 Protein tyrosine kinase Ank_2 PF12796.7 KDO21916.1 - 1e-52 176.6 15.7 2.3e-13 50.5 0.1 7.2 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO21916.1 - 6.4e-42 136.7 21.9 7.1e-05 22.9 0.1 14.1 13 1 1 14 14 14 7 Ankyrin repeat Ank_4 PF13637.6 KDO21916.1 - 1.3e-40 137.3 15.9 1.1e-08 35.4 0.1 9.4 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21916.1 - 4.8e-40 135.1 21.5 1e-07 32.1 0.0 10.4 3 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO21916.1 - 1.4e-23 82.2 44.3 0.0002 21.6 0.3 12.2 11 2 2 13 13 12 6 Ankyrin repeat Kinase-like PF14531.6 KDO21916.1 - 3.4e-08 33.2 0.0 0.0047 16.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO21916.1 - 1.2e-07 30.8 0.0 0.0016 17.3 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 KDO21916.1 - 8.8e-07 28.5 0.2 0.028 13.8 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO21916.1 - 5.8e-06 25.5 0.0 0.00039 19.5 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO21916.1 - 0.00028 20.0 0.3 0.55 9.2 0.1 2.4 2 0 0 2 2 2 2 Seadornavirus VP7 APH PF01636.23 KDO21916.1 - 0.00032 20.7 10.3 0.25 11.2 0.1 5.0 5 1 1 6 6 6 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO21916.1 - 0.018 14.0 0.2 0.63 8.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 KDO21917.1 - 3.8e-14 52.6 0.0 1.6e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21917.1 - 1.3e-10 41.1 0.0 7.9e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain TFIIIC_sub6 PF10419.9 KDO21920.1 - 5.6e-11 42.2 0.0 7.6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Pkinase_Tyr PF07714.17 KDO21921.1 - 4.7e-05 22.8 0.0 0.0008 18.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21921.1 - 0.00016 21.1 0.0 0.0019 17.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Cep57_CLD_2 PF14197.6 KDO21921.1 - 0.044 13.9 0.0 3.2 7.9 0.0 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FUSC PF04632.12 KDO21922.1 - 0.0068 15.0 0.9 0.0078 14.8 0.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family Nop10p PF04135.12 KDO21922.1 - 0.027 14.5 2.6 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Abhydrolase_8 PF06259.12 KDO21922.1 - 0.073 12.7 0.2 0.097 12.3 0.2 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-C3HC4_3 PF13920.6 KDO21922.1 - 0.081 12.8 8.2 0.71 9.8 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4685 PF15737.5 KDO21922.1 - 0.13 12.7 0.3 0.25 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) Auto_anti-p27 PF06677.12 KDO21922.1 - 0.13 12.4 0.4 0.13 12.4 0.4 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc-ribbons_6 PF07191.12 KDO21922.1 - 0.41 10.7 12.7 1.8 8.6 8.2 2.3 1 1 1 2 2 2 0 zinc-ribbons FANCL_C PF11793.8 KDO21922.1 - 0.43 10.8 7.7 0.76 10.0 6.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.7 KDO21922.1 - 0.66 10.0 14.5 8.5 6.5 14.6 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 KDO21922.1 - 1 9.1 0.1 1 9.1 0.1 4.9 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain TackOD1 PF18551.1 KDO21922.1 - 1.7 8.3 13.7 0.42 10.3 3.4 2.8 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 HypA PF01155.19 KDO21922.1 - 3.6 7.6 11.1 2.1 8.4 0.7 2.4 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pkinase PF00069.25 KDO21923.1 - 1.9e-43 148.8 0.0 2.4e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21923.1 - 5.7e-43 147.1 0.0 7.1e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO21923.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO21923.1 - 0.002 17.0 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO21923.1 - 0.0041 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO21923.1 - 0.0046 16.9 0.1 0.012 15.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KDO21923.1 - 0.01 15.5 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KDO21924.1 - 1.5e-32 113.0 0.0 1.9e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21924.1 - 1.1e-31 110.0 0.0 2e-31 109.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO21924.1 - 0.00043 19.2 0.0 0.00056 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO21924.1 - 0.0067 15.8 0.0 0.0088 15.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO21924.1 - 0.0081 15.5 0.0 0.0093 15.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF5475 PF17569.2 KDO21924.1 - 0.026 14.8 0.1 0.052 13.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5475) Haspin_kinase PF12330.8 KDO21924.1 - 0.095 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ank_3 PF13606.6 KDO21925.1 - 4.5e-06 26.6 0.2 0.067 13.8 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KDO21925.1 - 0.00015 22.1 2.5 0.3 11.6 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO21925.1 - 0.00027 21.5 0.2 0.00035 21.1 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO21925.1 - 0.0017 18.9 0.2 0.015 15.8 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO21925.1 - 0.0058 16.9 2.1 0.015 15.6 1.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TFIIIC_sub6 PF10419.9 KDO21926.1 - 2e-07 30.7 0.0 2.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Lactamase_B PF00753.27 KDO21927.1 - 4.4e-16 59.5 0.2 9.2e-16 58.4 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KDO21927.1 - 1.7e-10 40.7 0.0 3.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KDO21927.1 - 3e-05 23.6 0.1 0.00016 21.3 0.1 2.1 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KDO21927.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain W2 PF02020.18 KDO21928.1 - 1.3e-18 66.9 0.9 2.6e-18 65.9 0.9 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon LktC PF06261.11 KDO21928.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC MRG PF05712.13 KDO21928.1 - 0.035 13.4 0.1 2.9 7.1 0.0 2.1 1 1 0 2 2 2 0 MRG HAGH_C PF16123.5 KDO21929.1 - 8.8e-25 87.0 0.1 1.4e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KDO21929.1 - 1.5e-10 41.4 5.6 1.5e-10 41.4 5.6 2.4 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO21929.1 - 0.076 12.5 5.5 0.11 12.0 0.5 2.7 2 1 0 2 2 2 0 Beta-lactamase superfamily domain RCC1 PF00415.18 KDO21930.1 - 2.2e-43 146.6 10.5 4.7e-13 49.5 0.1 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO21930.1 - 5.4e-14 51.5 34.9 7.2e-07 28.8 1.1 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat zf-RING_2 PF13639.6 KDO21931.1 - 2.5e-09 37.3 11.1 2.5e-09 37.3 11.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KDO21931.1 - 3.3e-07 30.5 8.2 9.3e-07 29.0 8.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KDO21931.1 - 1.2e-05 25.1 3.4 1.2e-05 25.1 3.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KDO21931.1 - 0.00017 21.3 10.6 0.00017 21.3 10.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO21931.1 - 0.00018 21.3 8.7 0.00018 21.3 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO21931.1 - 0.00032 20.5 10.8 0.00032 20.5 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO21931.1 - 0.00043 20.2 3.9 0.00043 20.2 3.9 2.8 2 1 0 2 2 2 1 RING-type zinc-finger GOLGA2L5 PF15070.6 KDO21931.1 - 0.0026 16.5 3.5 0.004 15.9 3.5 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 zf-RING_5 PF14634.6 KDO21931.1 - 0.0056 16.6 11.9 0.0056 16.6 11.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO21931.1 - 0.026 14.6 4.4 0.093 12.8 4.4 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DivIC PF04977.15 KDO21931.1 - 0.081 12.7 2.7 0.13 12.0 1.5 1.9 1 1 0 1 1 1 0 Septum formation initiator zf-C3HC4_4 PF15227.6 KDO21931.1 - 0.14 12.3 13.2 0.16 12.1 8.9 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KDO21931.1 - 0.31 10.9 4.5 0.85 9.5 4.5 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YabA PF06156.13 KDO21931.1 - 0.35 11.5 2.3 0.64 10.7 1.4 1.9 2 0 0 2 2 1 0 Initiation control protein YabA zf-RING_10 PF16685.5 KDO21931.1 - 6 7.1 9.1 2.6 8.3 6.1 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 ARL2_Bind_BART PF11527.8 KDO21932.1 - 1.4e-17 63.9 1.2 1.5e-17 63.7 1.2 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Hydrolase_4 PF12146.8 KDO21933.1 - 2.6e-17 62.9 1.4 3.5e-17 62.5 1.4 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO21933.1 - 7.7e-17 61.8 0.5 1.2e-16 61.2 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO21933.1 - 8.5e-12 46.1 6.6 8.5e-12 46.1 6.6 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KDO21933.1 - 0.00075 19.4 0.0 0.58 9.9 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KDO21933.1 - 0.0037 16.8 0.4 0.014 14.9 0.4 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Asp2 PF16929.5 KDO21933.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Esterase PF00756.20 KDO21933.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2798 PF11391.8 KDO21935.1 - 0.61 10.2 2.8 0.74 9.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) EF-hand_1 PF00036.32 KDO21936.1 - 3.3e-10 38.8 0.2 4.2e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO21936.1 - 8.9e-08 32.5 0.4 1e-05 25.9 0.2 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO21936.1 - 8.7e-07 28.2 1.0 0.015 14.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO21936.1 - 1.9e-06 27.4 1.0 0.1 12.6 0.8 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KDO21936.1 - 5.1e-05 23.0 1.1 0.0007 19.4 0.1 2.8 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 KDO21936.1 - 0.082 13.2 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Ank_4 PF13637.6 KDO21937.1 - 3.8e-11 43.3 0.3 1.2e-06 29.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO21937.1 - 5.8e-09 36.4 0.8 0.00038 21.0 0.1 3.0 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO21937.1 - 3.3e-06 27.3 0.6 0.17 12.4 0.1 4.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO21937.1 - 1.1e-05 25.4 0.2 0.06 13.9 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KDO21937.1 - 0.0093 16.3 0.7 0.073 13.4 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DHHC PF01529.20 KDO21938.1 - 6.8e-27 94.2 13.1 1.1e-26 93.5 13.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2207 PF09972.9 KDO21938.1 - 0.22 10.2 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2534 PF10749.9 KDO21938.1 - 0.26 11.5 3.6 0.46 10.7 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) Glycos_transf_2 PF00535.26 KDO21940.1 - 1.2e-24 87.0 0.0 1.6e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KDO21940.1 - 8.1e-11 42.2 0.1 1.2e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KDO21940.1 - 2e-07 30.8 0.0 2.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2117 PF09890.9 KDO21940.1 - 0.025 14.0 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) RIIa PF02197.17 KDO21941.1 - 0.0006 19.4 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MHB PF16525.5 KDO21941.1 - 0.032 14.5 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Haemophore, haem-binding PQQ_3 PF13570.6 KDO21942.1 - 0.55 10.8 11.2 66 4.2 0.3 4.8 4 1 0 4 4 4 0 PQQ-like domain SPOR PF05036.13 KDO21945.1 - 0.059 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Sporulation related domain zf-CCCH PF00642.24 KDO21945.1 - 0.34 10.9 4.2 0.43 10.6 0.6 2.6 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KDO21945.1 - 0.72 10.4 3.5 8.3 7.1 1.0 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4106 PF13388.6 KDO21945.1 - 1.5 7.9 12.6 1.9 7.6 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TFIIA PF03153.13 KDO21945.1 - 1.8 8.5 9.2 1.9 8.4 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KDO21946.1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DHODB_Fe-S_bind PF10418.9 KDO21948.1 - 0.18 11.6 0.3 0.33 10.8 0.3 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Las1 PF04031.13 KDO21951.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Las1-like AMP-binding PF00501.28 KDO21952.1 - 6.8e-61 206.1 0.0 8.9e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 KDO21953.1 - 3.7e-67 226.5 0.0 4.3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO21953.1 - 5.2e-22 78.4 0.0 1.2e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KDO21953.1 - 3.4e-08 33.7 0.0 4.3e-06 26.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO21953.1 - 0.00083 18.2 0.1 0.0027 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO21953.1 - 0.0034 16.8 1.1 0.0071 15.7 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO21953.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Acetyltransf_10 PF13673.7 KDO21956.1 - 2.1e-16 60.0 0.0 2.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO21956.1 - 2.1e-06 28.0 0.0 2.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO21956.1 - 2.7e-06 27.7 0.0 4.2e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO21956.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 KDO21956.1 - 0.045 13.8 0.0 0.059 13.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TraI PF07057.11 KDO21956.1 - 0.16 12.1 0.0 0.58 10.3 0.0 1.7 1 1 1 2 2 2 0 DNA helicase TraI PLAC8 PF04749.17 KDO21957.1 - 2.7e-10 41.1 0.5 4.2e-10 40.5 0.5 1.3 1 0 0 1 1 1 1 PLAC8 family Rootletin PF15035.6 KDO21958.1 - 0.03 14.4 1.2 0.042 13.9 1.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Pkinase_Tyr PF07714.17 KDO21960.1 - 5.8e-43 147.1 0.0 7.8e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21960.1 - 6.1e-41 140.5 0.0 8.9e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO21960.1 - 0.00019 20.9 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO21960.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.7 KDO21960.1 - 0.037 14.4 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 KDO21960.1 - 0.067 12.1 0.0 8.5 5.2 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain EphA2_TM PF14575.6 KDO21960.1 - 0.11 13.4 0.1 0.21 12.5 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fe_hyd_lg_C PF02906.14 KDO21960.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain ABC_membrane PF00664.23 KDO21962.1 - 1.3e-99 333.4 29.3 7.1e-52 176.7 8.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO21962.1 - 1.2e-54 184.6 0.0 3.4e-34 118.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO21962.1 - 4.8e-11 42.5 1.2 0.00036 20.0 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KDO21962.1 - 0.0002 20.3 0.2 0.47 9.2 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 KDO21962.1 - 0.00076 19.5 0.7 0.21 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KDO21962.1 - 0.00077 19.9 3.9 0.15 12.5 0.7 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KDO21962.1 - 0.0016 18.6 4.6 1.1 9.5 0.4 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KDO21962.1 - 0.0021 17.7 0.1 0.0053 16.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO21962.1 - 0.0052 17.2 0.9 0.0094 16.3 0.1 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO21962.1 - 0.0059 16.9 0.6 0.11 12.7 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KDO21962.1 - 0.013 15.3 0.0 1 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KDO21962.1 - 0.04 13.5 0.4 0.79 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KDO21962.1 - 0.062 12.7 0.0 2.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KDO21962.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KDO21962.1 - 0.14 11.8 0.2 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO21962.1 - 0.15 11.6 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 KDO21962.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KDO21962.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF3918 PF13056.6 KDO21962.1 - 8.7 6.1 7.4 14 5.4 1.9 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Sec1 PF00995.23 KDO21963.1 - 3.4e-102 343.6 0.0 4e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Radical_SAM PF04055.21 KDO21963.1 - 0.059 13.8 0.0 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Radical SAM superfamily Mito_carr PF00153.27 KDO21965.1 - 6.9e-67 221.4 1.1 4.3e-25 87.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO21965.1 - 0.12 11.5 0.9 20 4.2 0.1 2.9 2 1 0 3 3 3 0 Gammaproteobacterial serine protease DUF5518 PF17647.1 KDO21965.1 - 0.32 11.1 7.8 1.2 9.3 0.5 3.5 3 2 0 3 3 3 0 Family of unknown function (DUF5518) Mito_carr PF00153.27 KDO21966.1 - 2.5e-71 235.7 1.0 5.1e-27 93.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO21966.1 - 0.013 14.7 0.6 4.1 6.5 0.1 2.7 3 1 0 3 3 3 0 Gammaproteobacterial serine protease CRCB PF02537.15 KDO21966.1 - 0.04 14.2 0.8 0.91 9.9 0.2 2.3 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) DUF5518 PF17647.1 KDO21966.1 - 0.3 11.3 5.3 1.1 9.5 0.0 3.5 3 1 1 4 4 4 0 Family of unknown function (DUF5518) Mito_carr PF00153.27 KDO21967.1 - 1e-71 236.9 1.0 2.8e-26 91.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO21967.1 - 0.00016 21.0 0.3 0.12 11.5 0.0 3.0 2 1 0 3 3 3 2 Gammaproteobacterial serine protease DUF5518 PF17647.1 KDO21967.1 - 0.027 14.6 5.6 3 8.0 0.0 3.9 2 1 2 4 4 4 0 Family of unknown function (DUF5518) Tim17 PF02466.19 KDO21967.1 - 0.11 12.8 2.8 0.14 12.6 0.3 2.4 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M54 PF07998.11 KDO21968.1 - 2.4e-10 40.7 0.1 5.6e-10 39.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_4 PF13583.6 KDO21968.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KDO21968.1 - 0.0091 16.2 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KDO21968.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Zincin_1 PF06262.11 KDO21968.1 - 0.023 14.8 0.2 0.049 13.7 0.2 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Reprolysin_3 PF13582.6 KDO21968.1 - 0.039 14.5 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KDO21968.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KDO21968.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KDO21968.1 - 0.21 10.1 0.9 0.33 9.5 0.9 1.2 1 0 0 1 1 1 0 Putative peptidase family IQ PF00612.27 KDO21969.1 - 2e-07 30.2 21.8 0.007 16.1 0.6 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 KDO21970.1 - 4e-53 180.3 0.0 5e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO21970.1 - 4.1e-51 173.9 0.0 5.4e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO21970.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO21970.1 - 6.8e-05 21.8 0.0 0.0001 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_8 PF13855.6 KDO21970.1 - 0.00018 21.2 0.8 0.00063 19.5 0.4 2.2 1 1 1 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO21970.1 - 0.00024 21.4 10.2 0.00032 21.0 0.5 3.4 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 KDO21970.1 - 0.017 14.1 0.0 0.081 11.8 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO21970.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CD34_antigen PF06365.12 KDO21970.1 - 0.081 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Kinase-like PF14531.6 KDO21970.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 KDO21970.1 - 0.81 10.5 5.6 24 6.0 0.3 3.9 3 1 1 4 4 3 0 Leucine Rich Repeat Pyr_redox_2 PF07992.14 KDO21971.1 - 9.3e-28 97.3 0.3 1.9e-19 70.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO21971.1 - 3.9e-14 53.0 2.0 4.9e-08 33.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO21971.1 - 3e-07 30.0 0.1 0.0067 15.7 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO21971.1 - 5.6e-07 29.0 2.6 0.018 14.1 0.3 2.8 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KDO21971.1 - 6.4e-07 29.3 5.9 0.0025 17.4 0.1 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO21971.1 - 7.5e-05 22.9 1.8 0.011 15.9 0.1 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KDO21971.1 - 7.5e-05 21.7 0.3 7.5e-05 21.7 0.3 2.3 2 1 1 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 KDO21971.1 - 0.00013 21.3 1.0 0.021 14.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 KDO21971.1 - 0.00013 22.0 3.0 0.0023 17.9 0.1 3.0 2 1 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KDO21971.1 - 0.00013 22.2 0.8 0.68 10.2 0.1 2.6 2 1 0 2 2 2 2 TrkA-N domain HI0933_like PF03486.14 KDO21971.1 - 0.00036 19.4 3.1 0.036 12.8 0.1 2.3 2 1 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.6 KDO21971.1 - 0.00074 18.7 0.6 0.17 11.0 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.21 KDO21971.1 - 0.0026 17.2 0.3 0.023 14.0 0.0 2.4 3 0 0 3 3 3 1 ThiF family NAD_binding_7 PF13241.6 KDO21971.1 - 0.0048 17.3 1.1 0.61 10.6 0.1 2.4 1 1 1 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KDO21971.1 - 0.012 14.8 0.1 0.012 14.8 0.1 2.4 3 1 0 3 3 3 0 FAD binding domain GIDA PF01134.22 KDO21971.1 - 0.021 13.9 3.8 0.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KDO21971.1 - 0.024 13.9 3.0 0.76 9.0 0.4 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KDO21971.1 - 0.034 14.0 0.9 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KDO21971.1 - 0.11 12.1 0.2 0.28 10.8 0.2 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KDO21971.1 - 0.16 12.2 3.0 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 KDO21971.1 - 1.9 7.5 7.2 1.3 8.0 1.0 2.3 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KDO21973.1 - 2.2e-37 128.9 2.1 2.6e-37 128.6 2.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO21973.1 - 8.8e-15 55.0 1.0 8.2e-08 32.7 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO21973.1 - 6.3e-08 32.2 0.1 4.8e-05 22.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO21973.1 - 1.2e-07 31.1 3.1 0.039 13.0 0.5 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KDO21973.1 - 2.3e-06 27.5 8.9 0.0015 18.2 0.1 3.2 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KDO21973.1 - 7e-05 22.9 0.5 0.95 9.4 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KDO21973.1 - 0.00012 21.4 0.1 0.018 14.2 0.1 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KDO21973.1 - 0.00021 21.5 2.2 0.017 15.3 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KDO21973.1 - 0.00038 20.9 0.3 0.74 10.3 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 KDO21973.1 - 0.0004 19.2 0.4 0.28 9.9 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein ThiF PF00899.21 KDO21973.1 - 0.0009 18.7 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 ThiF family Thi4 PF01946.17 KDO21973.1 - 0.0029 16.9 1.4 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 KDO21973.1 - 0.0034 17.6 0.6 0.9 9.8 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain Trp_halogenase PF04820.14 KDO21973.1 - 0.0047 15.8 3.8 0.01 14.7 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KDO21973.1 - 0.0092 15.3 1.9 0.23 10.7 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 KDO21973.1 - 0.013 14.6 2.1 0.11 11.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KDO21973.1 - 0.088 11.9 7.1 0.96 8.5 0.6 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KDO21973.1 - 0.92 9.4 3.5 23 4.8 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KDO21974.1 - 1.1e-27 97.0 0.3 1.3e-27 96.8 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO21974.1 - 2.7e-14 53.5 1.3 3.7e-08 33.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO21974.1 - 2.9e-09 36.6 0.1 3e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO21974.1 - 3.2e-08 33.5 10.6 0.00054 19.6 0.4 3.9 2 2 2 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KDO21974.1 - 3.8e-07 30.2 0.7 0.026 14.5 0.1 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KDO21974.1 - 3.9e-07 29.5 1.6 0.02 14.0 0.2 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.6 KDO21974.1 - 1.7e-06 27.5 0.3 7.5e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KDO21974.1 - 4.4e-05 22.5 3.3 0.0003 19.8 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase TrkA_N PF02254.18 KDO21974.1 - 0.0001 22.5 1.0 0.22 11.8 0.1 2.6 2 0 0 2 2 2 2 TrkA-N domain ThiF PF00899.21 KDO21974.1 - 0.0001 21.7 0.1 0.0021 17.4 0.0 2.7 3 0 0 3 3 3 1 ThiF family NAD_binding_8 PF13450.6 KDO21974.1 - 0.00036 20.7 1.1 0.1 12.9 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KDO21974.1 - 0.0016 18.9 0.4 1.8 9.0 0.1 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 KDO21974.1 - 0.0094 15.2 1.0 1.7 7.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KDO21974.1 - 0.014 14.1 2.6 2.2 6.9 0.2 3.2 3 1 0 3 3 3 0 HI0933-like protein TRAP-delta PF05404.12 KDO21974.1 - 0.057 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) FAD_binding_3 PF01494.19 KDO21974.1 - 0.057 12.7 2.6 2.9 7.0 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KDO21974.1 - 0.15 12.3 1.9 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KDO21974.1 - 0.16 11.5 0.6 13 5.3 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KDO21974.1 - 0.17 11.6 0.1 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KDO21974.1 - 0.26 11.2 1.6 4.6 7.1 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KDO21974.1 - 0.51 9.3 4.5 6.8 5.7 0.4 2.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KDO21974.1 - 1.3 8.1 9.7 3.4 6.6 0.4 3.3 2 2 2 4 4 4 0 Glucose inhibited division protein A PDEase_I PF00233.19 KDO21976.1 - 4.3e-66 223.0 5.9 4.3e-66 223.0 5.9 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KDO21976.1 - 3.9e-29 102.0 0.5 8.4e-14 52.3 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 KDO21976.1 - 4.8e-12 46.4 0.0 4.8e-07 30.1 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KDO21976.1 - 6.2e-06 26.6 0.0 0.00025 21.4 0.0 2.6 2 0 0 2 2 2 1 GAF domain CCDC23 PF15674.5 KDO21976.1 - 0.075 13.0 0.1 0.28 11.2 0.1 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 HD PF01966.22 KDO21976.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 HD domain Ysc84 PF04366.12 KDO21977.1 - 1.5e-26 92.7 0.0 1.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 KDO21978.1 - 1.8e-18 66.4 3.4 2.7e-18 65.8 3.4 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-ribbon_3 PF13248.6 KDO21978.1 - 0.0041 16.5 0.9 2.3 7.8 0.3 2.7 2 0 0 2 2 2 2 zinc-ribbon domain GATA PF00320.27 KDO21978.1 - 0.03 13.9 0.2 0.03 13.9 0.2 3.5 3 1 0 3 3 3 0 GATA zinc finger Rpr2 PF04032.16 KDO21978.1 - 0.23 11.8 6.7 11 6.4 0.7 3.1 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 KDO21978.1 - 1.8 8.7 8.8 78 3.4 8.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon zn-ribbon_14 PF16503.5 KDO21978.1 - 3 7.4 6.6 0.65 9.6 0.2 2.8 3 0 0 3 3 3 0 Zinc-ribbon zf-RING_5 PF14634.6 KDO21978.1 - 5.1 7.1 12.4 12 5.9 11.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF1325 PF07039.11 KDO21981.1 - 1.4e-27 96.4 0.0 2.1e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 KDO21981.1 - 0.0011 19.4 0.3 0.31 11.5 0.1 2.3 2 0 0 2 2 2 2 Agenet domain Tudor_3 PF18115.1 KDO21981.1 - 0.0013 18.5 0.7 0.0019 18.0 0.1 1.6 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 KDO21981.1 - 0.016 15.0 0.0 0.89 9.4 0.0 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 KDO21981.1 - 0.029 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TetR_C_24 PF17932.1 KDO21981.1 - 0.043 14.1 0.3 0.072 13.4 0.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GDA1_CD39 PF01150.17 KDO21982.1 - 3.9e-35 121.3 0.0 1.6e-34 119.3 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF5317 PF17248.2 KDO21982.1 - 0.26 11.3 0.7 15 5.6 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5317) AA_permease_2 PF13520.6 KDO21983.1 - 4.4e-22 78.5 29.6 1.4e-14 53.7 13.7 2.2 1 1 1 2 2 2 2 Amino acid permease Acyl_transf_3 PF01757.22 KDO21983.1 - 0.17 10.9 23.9 0.014 14.4 16.9 2.2 2 0 0 2 2 2 0 Acyltransferase family AA_permease_2 PF13520.6 KDO21984.1 - 5.5e-44 150.7 46.5 7e-44 150.3 46.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO21985.1 - 5.1e-12 45.4 0.4 5.9e-12 45.1 0.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO21985.1 - 0.0018 16.9 3.4 0.0027 16.4 3.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO21986.1 - 1.8e-41 142.4 40.7 1e-38 133.3 40.6 2.2 1 1 0 1 1 1 1 Amino acid permease CaKB PF03185.15 KDO21986.1 - 0.38 10.4 2.5 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit Hexapep_2 PF14602.6 KDO21986.1 - 7.7 6.4 6.0 1.3 8.8 1.1 2.2 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase AA_permease_2 PF13520.6 KDO21988.1 - 4.8e-43 147.6 45.4 6.3e-43 147.2 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1129 PF06570.11 KDO21988.1 - 2 7.8 10.8 0.25 10.8 4.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) AA_permease_2 PF13520.6 KDO21989.1 - 4.7e-50 170.7 41.6 6.7e-50 170.1 41.6 1.2 1 0 0 1 1 1 1 Amino acid permease Tetraspanin PF00335.20 KDO21989.1 - 0.012 15.3 22.8 0.52 10.0 2.9 3.4 2 1 1 3 3 3 0 Tetraspanin family Rotamase_2 PF13145.6 KDO21990.1 - 0.14 13.0 2.8 0.2 12.5 2.8 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain TTL PF03133.15 KDO21991.1 - 1.9e-82 276.7 0.0 3e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO21991.1 - 2e-05 24.0 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO21991.1 - 0.0096 15.2 0.0 0.25 10.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp LtrA PF06772.11 KDO21992.1 - 2e-24 86.5 16.7 3.7e-20 72.4 6.1 2.2 1 1 1 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Ion_trans_2 PF07885.16 KDO21992.1 - 0.17 11.9 3.9 0.89 9.6 1.6 3.2 3 0 0 3 3 3 0 Ion channel MCCD1 PF15707.5 KDO21993.1 - 0.076 13.5 2.1 0.099 13.1 1.0 1.7 1 1 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Csm1_N PF18504.1 KDO21993.1 - 1.2 9.6 3.5 0.57 10.6 0.6 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain iPGM_N PF06415.13 KDO21995.1 - 4.2e-05 23.1 0.4 6.9e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) DEC-1_N PF04625.13 KDO22000.1 - 0.039 13.0 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NOG1_N PF17835.1 KDO22002.1 - 1.7e-18 67.1 0.5 1.7e-18 67.1 0.5 1.7 2 0 0 2 2 2 1 NOG1 N-terminal helical domain Ank_2 PF12796.7 KDO22003.1 - 1.6e-122 400.4 57.3 5.6e-13 49.3 0.2 17.8 6 6 13 19 19 19 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22003.1 - 4.6e-95 310.9 45.4 8.5e-07 29.4 0.3 21.4 14 7 7 22 22 22 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22003.1 - 2.2e-73 233.4 53.3 0.0021 18.4 0.0 31.4 33 0 0 33 33 33 16 Ankyrin repeat Ank_5 PF13857.6 KDO22003.1 - 6.1e-66 217.6 84.1 1.6e-08 34.6 1.2 23.8 12 5 11 23 23 23 16 Ankyrin repeats (many copies) Ank PF00023.30 KDO22003.1 - 2.2e-51 170.1 82.7 0.0012 19.2 0.4 27.0 27 1 0 27 27 27 15 Ankyrin repeat Pkinase PF00069.25 KDO22003.1 - 6.9e-42 143.6 0.0 1.5e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22003.1 - 1.3e-33 116.4 0.0 3e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO22003.1 - 0.00031 20.2 0.0 0.00086 18.7 0.0 1.7 1 0 0 1 1 1 1 Kinase-like TetR_C_30 PF17939.1 KDO22003.1 - 0.032 14.5 0.3 0.14 12.4 0.3 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Phage_T7_Capsid PF05396.11 KDO22003.1 - 1.5 9.2 7.2 17 5.8 0.2 4.3 3 0 0 3 3 3 0 Phage T7 capsid assembly protein DUF3551 PF12071.8 KDO22005.1 - 0.042 13.9 1.5 0.14 12.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) RHH_4 PF13467.6 KDO22005.1 - 0.14 12.1 0.5 6.3 6.8 0.5 2.3 1 1 0 1 1 1 0 Ribbon-helix-helix domain Pkinase_Tyr PF07714.17 KDO22006.1 - 2.2e-14 53.4 0.0 2.1e-13 50.2 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22006.1 - 8.6e-14 51.5 0.0 2.8e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain SAP30_Sin3_bdg PF13867.6 KDO22007.1 - 7.8e-10 38.9 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Forkhead PF00250.18 KDO22007.1 - 2.5e-07 30.9 0.0 5.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain zf-HC5HC2H PF13771.6 KDO22007.1 - 0.00057 20.1 1.8 0.0011 19.2 1.8 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KDO22007.1 - 0.0095 16.1 1.2 0.019 15.1 1.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KDO22007.1 - 0.017 15.0 6.4 0.037 13.9 6.4 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_S10 PF00450.22 KDO22008.1 - 0.2 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase PH PF00169.29 KDO22009.1 - 5.2e-12 46.2 0.0 8.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO22009.1 - 0.0034 17.8 0.0 0.0097 16.3 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO22009.1 - 0.0061 16.6 0.0 0.043 13.9 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO22009.1 - 0.015 15.6 0.2 0.12 12.7 0.2 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 KDO22009.1 - 0.22 11.9 0.0 10 6.5 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.29 KDO22010.1 - 3e-10 40.5 0.0 4.9e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO22010.1 - 1.9e-06 28.2 0.0 3.3e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO22010.1 - 0.012 15.9 0.2 0.29 11.4 0.2 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KDO22011.1 - 6.9e-15 55.4 0.0 8.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO22011.1 - 1.2e-08 35.4 0.1 2.2e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO22011.1 - 0.00067 19.9 0.3 0.007 16.6 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO22011.1 - 0.0037 17.6 0.1 0.14 12.5 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KDO22012.1 - 3.8e-12 46.6 0.0 6.4e-12 45.9 0.0 1.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KDO22012.1 - 1.4e-05 25.4 0.0 5.2e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO22012.1 - 4.7e-05 23.6 2.7 0.00015 21.9 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KDO22013.1 - 1.5e-13 51.1 0.0 2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO22013.1 - 4.3e-05 23.7 0.3 0.00055 20.2 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO22013.1 - 0.00053 20.4 0.5 0.0016 18.8 0.5 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO22013.1 - 0.079 13.3 0.2 0.42 11.0 0.2 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 KDO22013.1 - 0.16 12.1 0.1 1.2 9.3 0.1 2.0 1 1 0 1 1 1 0 PH domain PH PF00169.29 KDO22014.1 - 3e-15 56.6 0.0 3.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO22014.1 - 3.1e-07 30.8 0.5 4.8e-07 30.1 0.5 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO22014.1 - 0.0034 17.8 0.0 0.0066 16.8 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO22014.1 - 0.0036 17.5 0.5 0.018 15.3 0.5 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO22014.1 - 0.07 13.2 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KDO22015.1 - 4.1e-13 49.8 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO22015.1 - 1.4e-06 28.6 0.0 4.8e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO22015.1 - 8.6e-05 22.6 0.0 0.0006 19.9 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO22015.1 - 0.00034 20.8 0.1 0.0073 16.6 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO22015.1 - 0.0053 17.1 0.2 0.34 11.3 0.0 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KDO22016.1 - 3.2e-12 46.9 0.0 4.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO22016.1 - 0.0013 19.1 0.8 0.0031 17.9 0.8 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO22016.1 - 0.0044 17.1 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.6 KDO22016.1 - 0.0049 17.1 0.9 0.082 13.2 0.9 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO22016.1 - 0.008 16.5 0.1 0.057 13.8 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain HGTP_anticodon PF03129.20 KDO22017.1 - 1.1e-19 70.3 0.0 3.3e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KDO22017.1 - 1.8e-09 37.8 0.0 4.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 KDO22017.1 - 1.3e-06 28.5 1.5 3.3e-06 27.1 1.5 1.7 1 0 0 1 1 1 1 WHEP-TRS domain DUF569 PF04601.13 KDO22019.1 - 0.036 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF569) RicinB_lectin_2 PF14200.6 KDO22019.1 - 0.2 12.4 3.0 0.45 11.3 0.3 2.1 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like AA_kinase PF00696.28 KDO22020.1 - 1e-27 97.3 0.7 1.3e-27 97.0 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family Q_salvage PF10343.9 KDO22021.1 - 2.4e-32 112.7 0.0 3.8e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Pkinase_Tyr PF07714.17 KDO22022.1 - 7e-52 176.3 0.0 8.3e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22022.1 - 1.9e-51 175.0 0.0 2.3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO22022.1 - 5.3e-05 22.7 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO22022.1 - 0.00013 20.9 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO22022.1 - 0.0053 16.7 0.4 0.035 14.0 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO22022.1 - 0.033 13.5 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Leu_leader PF08054.11 KDO22022.1 - 0.039 13.5 1.2 0.081 12.5 1.2 1.5 1 0 0 1 1 1 0 Leucine operon leader peptide AP_endonuc_2 PF01261.24 KDO22022.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Pkinase_Tyr PF07714.17 KDO22025.1 - 3.2e-49 167.6 0.0 4.9e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22025.1 - 1.1e-47 162.7 0.0 1.4e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO22025.1 - 0.00035 20.6 0.0 0.012 15.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO22025.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO22025.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO22025.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO22025.1 - 0.13 11.6 0.1 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FF PF01846.19 KDO22026.1 - 5.2e-12 45.8 0.3 2e-10 40.7 0.2 2.6 2 0 0 2 2 2 1 FF domain WW PF00397.26 KDO22026.1 - 3.9e-08 33.2 3.0 0.00097 19.2 0.5 2.4 2 0 0 2 2 2 2 WW domain Rrn6 PF10214.9 KDO22026.1 - 0.004 15.7 0.8 0.48 8.8 0.3 2.0 1 1 1 2 2 2 2 RNA polymerase I-specific transcription-initiation factor DUF2457 PF10446.9 KDO22026.1 - 0.46 9.6 9.1 0.059 12.5 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myb_Cef PF11831.8 KDO22026.1 - 1 8.9 8.7 2.4 7.6 8.7 1.6 1 0 0 1 1 1 0 pre-mRNA splicing factor component PRIMA1 PF16101.5 KDO22026.1 - 9 6.4 8.1 17 5.4 2.5 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PX PF00787.24 KDO22027.1 - 1.2e-06 28.5 0.0 3.5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 PX domain Thaumatin PF00314.17 KDO22029.1 - 0.00015 21.5 6.1 0.017 14.8 1.8 3.1 1 1 1 2 2 2 2 Thaumatin family Pheromone PF08015.11 KDO22029.1 - 2.3 9.3 7.9 3.9 8.6 0.2 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone ETRAMP PF09716.10 KDO22030.1 - 0.024 14.7 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-CGNR PF11706.8 KDO22030.1 - 0.089 12.7 2.2 1.3 8.9 0.2 2.7 2 0 0 2 2 2 0 CGNR zinc finger BNR PF02012.20 KDO22030.1 - 0.22 11.7 2.4 0.49 10.6 0.1 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF1418 PF07214.12 KDO22031.1 - 0.55 10.1 2.3 8.8 6.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Abhydrolase_6 PF12697.7 KDO22033.1 - 0.0013 19.4 4.4 0.002 18.7 4.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KDO22033.1 - 0.022 14.6 0.4 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 Lipase (class 3) LCAT PF02450.15 KDO22033.1 - 0.067 12.4 0.1 0.097 11.8 0.1 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LCAT PF02450.15 KDO22034.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DOT1 PF08123.13 KDO22035.1 - 5.6e-12 45.6 0.0 2.8e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KDO22035.1 - 2e-05 24.4 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KDO22035.1 - 3.9e-05 23.2 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KDO22035.1 - 0.003 17.3 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KDO22035.1 - 0.027 15.2 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KDO22035.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PsbX PF06596.11 KDO22037.1 - 1.9 8.6 9.8 1.5 8.9 3.6 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) TALPID3 PF15324.6 KDO22037.1 - 6.3 4.3 27.7 8.3 3.9 27.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF3357 PF11837.8 KDO22038.1 - 0.088 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) EamA PF00892.20 KDO22040.1 - 5.5e-06 26.6 11.7 5.5e-06 26.6 11.7 3.1 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KDO22040.1 - 3.4e-05 23.2 2.7 9.5e-05 21.8 2.7 1.8 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 KDO22040.1 - 9.9e-05 21.6 1.2 9.9e-05 21.6 1.2 2.2 3 0 0 3 3 3 1 Nucleotide-sugar transporter SLC35F PF06027.12 KDO22040.1 - 0.00026 20.6 5.4 0.00026 20.6 5.4 1.6 2 0 0 2 2 2 1 Solute carrier family 35 ATP-synt_ab PF00006.25 KDO22042.1 - 3.9e-105 350.2 0.0 5.6e-105 349.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KDO22042.1 - 1.5e-39 134.6 0.0 2.5e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KDO22042.1 - 1.1e-09 38.6 0.8 2.9e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 KDO22042.1 - 0.1 13.1 0.1 0.33 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 KDO22043.1 - 2.6e-11 43.2 0.2 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KDO22043.1 - 8.8e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 KDO22043.1 - 0.00041 20.3 0.3 0.18 11.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KDO22043.1 - 0.021 14.7 0.0 0.21 11.5 0.0 2.3 2 1 0 2 2 2 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KDO22043.1 - 0.038 13.6 0.1 0.099 12.2 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KDO22043.1 - 0.059 13.4 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding domain UPF0449 PF15136.6 KDO22043.1 - 0.24 11.9 4.6 0.37 11.3 0.6 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 V-SNARE PF05008.15 KDO22043.1 - 0.62 10.5 9.9 0.19 12.1 4.6 2.6 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Atg14 PF10186.9 KDO22043.1 - 1.3 8.0 6.9 2.1 7.3 6.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KDO22043.1 - 4.3 6.8 9.0 0.94 9.0 4.9 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Csm1_N PF18504.1 KDO22043.1 - 4.7 7.6 15.4 0.94 9.9 8.8 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain VGCC_beta4Aa_N PF12052.8 KDO22044.1 - 3.6 7.8 4.8 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal PHTB1_N PF14727.6 KDO22045.1 - 5.7e-115 385.0 0.0 8.5e-115 384.4 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KDO22045.1 - 0.00063 18.9 0.0 0.00099 18.3 0.0 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_C PF14728.6 KDO22046.1 - 1.8e-13 50.4 0.1 2e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 PTHB1 C-terminus DUF2527 PF10736.9 KDO22048.1 - 0.099 12.5 0.7 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) RGS PF00615.19 KDO22051.1 - 0.0019 18.4 0.6 0.012 15.8 0.0 2.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain Ank PF00023.30 KDO22051.1 - 0.098 13.2 0.1 0.42 11.1 0.1 2.2 1 0 0 1 1 1 0 Ankyrin repeat IQ PF00612.27 KDO22051.1 - 0.92 9.5 9.8 0.054 13.3 1.6 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif bZIP_1 PF00170.21 KDO22053.1 - 0.37 10.9 4.5 0.8 9.9 4.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor SH3_19 PF18597.1 KDO22055.1 - 0.048 13.5 0.4 0.1 12.4 0.4 1.5 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain Hexapep PF00132.24 KDO22056.1 - 1.4e-16 59.5 15.4 1.3e-06 27.9 0.4 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KDO22056.1 - 1.8e-08 34.0 13.1 8.1e-06 25.5 1.1 3.8 3 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KDO22056.1 - 0.0047 15.9 0.8 0.01 14.8 0.6 1.6 1 1 1 2 2 2 1 L-fucokinase TMEM208_SND2 PF05620.11 KDO22057.1 - 3.1e-26 92.1 2.8 7.6e-24 84.4 2.8 2.0 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF3395 PF11875.8 KDO22058.1 - 1.1e-13 51.4 0.0 0.00013 21.9 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF3395) Gal_Lectin PF02140.18 KDO22058.1 - 1.4e-05 25.4 0.0 4 7.9 0.0 4.6 5 0 0 5 5 5 3 Galactose binding lectin domain zf-RanBP PF00641.18 KDO22058.1 - 0.18 11.1 0.2 0.34 10.3 0.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF4187 PF13821.6 KDO22058.1 - 2.2 8.2 6.5 1.6 8.6 2.8 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) Myb_DNA-binding PF00249.31 KDO22059.1 - 1.5e-43 146.8 6.9 1.7e-15 56.9 0.4 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO22059.1 - 3.4e-31 107.3 7.8 4e-15 55.8 0.2 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO22059.1 - 2.6e-06 27.3 0.2 0.018 14.9 0.1 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 KDO22059.1 - 3.5e-06 27.0 0.1 0.027 14.5 0.0 3.2 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 KDO22059.1 - 2e-05 24.7 1.0 0.24 11.6 0.1 3.2 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 KDO22059.1 - 0.0014 18.9 6.0 0.46 10.8 0.7 3.4 2 1 1 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KDO22059.1 - 0.039 14.0 0.3 0.88 9.7 0.1 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KDO22059.1 - 0.14 12.6 9.8 1.2 9.6 1.0 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain RCC1 PF00415.18 KDO22060.1 - 4.3e-54 180.9 24.4 1.3e-11 44.9 0.3 8.6 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO22060.1 - 1.1e-19 69.6 45.1 1e-05 25.2 0.2 8.0 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 KDO22060.1 - 0.0026 17.4 1.7 0.0048 16.6 1.7 1.5 1 0 0 1 1 1 1 SAP domain Pox_Ag35 PF03286.14 KDO22060.1 - 0.023 14.5 8.4 0.049 13.4 5.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BUD22 PF09073.10 KDO22060.1 - 0.038 13.4 6.3 0.056 12.8 3.7 2.0 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KDO22060.1 - 0.062 11.5 6.1 0.12 10.6 6.1 1.4 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KDO22060.1 - 0.22 10.8 16.3 0.46 9.8 16.3 1.5 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KDO22060.1 - 0.25 11.2 10.4 1.8 8.4 7.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KDO22060.1 - 0.4 8.7 16.6 0.64 8.0 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KDO22060.1 - 1.4 8.8 10.6 1.8 8.5 7.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 KDO22060.1 - 3 7.9 11.9 32 4.5 10.5 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4407 PF14362.6 KDO22060.1 - 6.2 6.1 6.4 1.1 8.6 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) C2 PF00168.30 KDO22061.1 - 0.003 17.8 0.0 0.0058 16.9 0.0 1.6 2 0 0 2 2 2 1 C2 domain C2 PF00168.30 KDO22063.1 - 8.4e-24 83.8 0.0 1.5e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain Pex24p PF06398.11 KDO22063.1 - 0.0005 19.2 2.5 0.0029 16.6 0.5 2.3 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Spc7 PF08317.11 KDO22063.1 - 0.042 12.7 10.0 0.062 12.2 10.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1501 PF07394.12 KDO22063.1 - 0.075 12.1 3.7 0.11 11.5 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TMF_TATA_bd PF12325.8 KDO22063.1 - 0.1 12.8 6.0 0.2 11.9 6.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4936 PF16290.5 KDO22063.1 - 0.52 11.0 13.1 0.18 12.5 6.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4936) Atg14 PF10186.9 KDO22063.1 - 9.4 5.2 8.7 14 4.6 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gly-zipper_Omp PF13488.6 KDO22064.1 - 0.00029 20.8 10.4 0.00077 19.4 10.4 1.7 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.6 KDO22064.1 - 0.00061 19.5 8.5 0.00061 19.5 8.5 1.8 2 0 0 2 2 2 1 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 KDO22064.1 - 0.0048 16.6 7.5 0.013 15.3 7.5 1.7 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 KDO22064.1 - 0.2 11.5 13.0 0.75 9.7 13.0 2.0 1 1 0 1 1 1 0 Glycine zipper 2TM domain BTB_2 PF02214.22 KDO22065.1 - 5.1e-10 39.6 0.0 9.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain C2 PF00168.30 KDO22066.1 - 3.8e-18 65.7 0.0 7.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain TMF_DNA_bd PF12329.8 KDO22066.1 - 0.0044 17.0 4.5 0.0044 17.0 4.5 13.6 10 5 6 16 16 16 3 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.9 KDO22066.1 - 0.0052 17.0 0.3 0.0052 17.0 0.3 5.1 3 2 1 4 4 4 1 Predicted coiled-coil domain-containing protein Pex24p PF06398.11 KDO22066.1 - 0.056 12.4 4.4 0.11 11.5 4.4 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Pyr_redox_2 PF07992.14 KDO22067.1 - 8.9e-50 169.6 0.5 1.5e-49 168.8 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO22067.1 - 8.8e-27 93.5 0.6 6.8e-26 90.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO22067.1 - 6.9e-17 61.8 2.0 5.2e-12 46.2 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO22067.1 - 4.7e-09 35.9 0.8 8.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO22067.1 - 2.1e-07 30.7 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO22067.1 - 2.9e-07 29.6 6.6 3e-05 22.9 0.2 3.1 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 KDO22067.1 - 4.2e-07 30.1 1.1 0.00033 20.8 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KDO22067.1 - 2.3e-06 27.1 0.2 0.00073 18.9 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KDO22067.1 - 7.3e-06 25.4 2.4 0.0014 17.9 0.1 2.7 2 1 0 2 2 2 2 Thi4 family 3HCDH_N PF02737.18 KDO22067.1 - 9.8e-06 25.6 1.5 0.0032 17.4 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KDO22067.1 - 1.3e-05 24.5 0.2 1.3e-05 24.5 0.2 2.9 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KDO22067.1 - 2.5e-05 24.0 0.1 0.052 13.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KDO22067.1 - 8.5e-05 21.8 0.4 0.0051 16.0 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KDO22067.1 - 0.0018 17.9 2.4 1.1 8.9 0.3 3.7 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KDO22067.1 - 0.0019 18.5 0.3 0.24 11.7 0.1 2.6 2 0 0 2 2 2 1 TrkA-N domain XdhC_C PF13478.6 KDO22067.1 - 0.022 15.2 0.1 1.6 9.3 0.0 2.6 2 1 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 KDO22067.1 - 0.028 13.5 0.3 1.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 KDO22067.1 - 0.045 12.9 0.0 4.9 6.2 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Wyosine_form PF08608.12 KDO22067.1 - 0.069 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Wyosine base formation FAD_binding_3 PF01494.19 KDO22067.1 - 0.11 11.7 1.1 1 8.5 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain TH1 PF04858.13 KDO22068.1 - 1.5e-82 278.1 1.0 2.2e-82 277.6 1.0 1.1 1 0 0 1 1 1 1 TH1 protein WW PF00397.26 KDO22068.1 - 4.8e-16 58.5 6.1 1.2e-08 34.9 2.1 2.5 2 0 0 2 2 2 2 WW domain DUF2992 PF11208.8 KDO22068.1 - 0.64 10.3 12.8 1.5 9.1 12.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Nucleo_P87 PF07267.11 KDO22068.1 - 4.4 6.1 11.8 6.9 5.4 11.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRM_1 PF00076.22 KDO22069.1 - 1.5e-33 114.4 0.4 2.4e-15 56.1 0.6 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO22069.1 - 4.2e-12 46.0 0.3 8.4e-07 29.0 0.3 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO22069.1 - 0.098 12.7 0.4 14 5.8 0.2 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PX PF00787.24 KDO22070.1 - 2.3e-18 66.2 0.0 9.1e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 PX domain ANAPC3 PF12895.7 KDO22071.1 - 1.6e-11 44.3 24.5 1.2e-06 28.7 0.4 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KDO22071.1 - 7.1e-11 41.4 19.7 0.0021 18.0 0.6 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO22071.1 - 7.2e-11 42.4 3.1 0.028 14.9 0.1 5.2 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO22071.1 - 7.9e-07 29.1 0.8 0.0043 17.2 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO22071.1 - 9e-07 29.1 12.9 0.00046 20.6 0.2 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO22071.1 - 5.4e-05 23.7 0.1 0.0077 16.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22071.1 - 0.00029 21.4 2.9 2.2 9.3 0.0 5.4 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22071.1 - 0.00081 19.6 7.5 0.024 14.9 0.2 4.6 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22071.1 - 0.0013 18.6 4.0 0.21 11.7 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22071.1 - 0.0017 18.1 0.3 0.0017 18.1 0.3 5.1 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3699 PF12480.8 KDO22071.1 - 0.0049 17.0 0.0 0.033 14.4 0.0 2.5 2 1 1 3 3 2 1 Protein of unknown function (DUF3699) TPR_10 PF13374.6 KDO22071.1 - 0.0063 16.3 0.2 24 5.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KDO22071.1 - 0.01 15.8 0.1 0.01 15.8 0.1 3.7 2 2 1 4 4 4 0 Putative TPR-like repeat TPR_8 PF13181.6 KDO22071.1 - 0.017 15.3 9.1 0.32 11.3 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KDO22071.1 - 0.07 12.8 1.0 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 baeRF_family6 PF18848.1 KDO22071.1 - 0.14 12.6 1.2 58 4.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 6 TPR_4 PF07721.14 KDO22071.1 - 0.18 12.5 1.1 1.6 9.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO22071.1 - 2.1 8.5 9.6 9 6.5 0.1 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat UCH PF00443.29 KDO22072.1 - 2.4e-40 138.6 0.1 4e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO22072.1 - 7.1e-15 55.4 0.4 1.2e-12 48.1 0.4 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KDO22072.1 - 5e-09 35.8 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KDO22072.1 - 2.3e-05 24.9 0.0 0.17 12.5 0.1 2.6 2 0 0 2 2 2 2 DUSP domain zf-RanBP PF00641.18 KDO22072.1 - 0.0023 17.2 1.6 0.0023 17.2 1.6 3.0 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Rad60-SLD PF11976.8 KDO22072.1 - 0.0058 16.4 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KDO22072.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Fer4_16 PF13484.6 KDO22072.1 - 0.052 14.5 2.1 4.8 8.2 0.0 4.7 5 0 0 5 5 5 0 4Fe-4S double cluster binding domain RecR PF02132.15 KDO22072.1 - 2.6 7.7 12.1 1.6 8.4 0.3 4.0 4 0 0 4 4 4 0 RecR protein OrfB_Zn_ribbon PF07282.11 KDO22072.1 - 9.3 6.3 8.9 0.31 11.0 0.3 3.2 4 0 0 4 4 4 0 Putative transposase DNA-binding domain Ribosomal_S8e PF01201.22 KDO22073.1 - 1.5e-56 190.4 1.3 1.7e-56 190.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e EF-hand_7 PF13499.6 KDO22074.1 - 3.9e-08 33.6 0.8 1.3e-07 32.0 1.2 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO22074.1 - 2.8e-06 26.8 0.1 1.5e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KDO22074.1 - 6.2e-05 22.3 0.1 0.00073 18.9 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KDO22074.1 - 0.0012 18.7 0.1 0.0039 17.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO22074.1 - 0.0054 16.2 0.1 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 KDO22074.1 - 0.016 15.6 0.4 0.5 10.7 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain Proteasome PF00227.26 KDO22075.1 - 1.9e-49 167.8 0.1 2.4e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO22075.1 - 2.3e-15 55.9 0.1 4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 KDO22075.1 - 0.014 14.1 0.0 0.04 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5018) TMEM52 PF14979.6 KDO22075.1 - 0.1 12.5 0.1 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane 52 YTH PF04146.15 KDO22077.1 - 1.4e-27 96.6 0.2 8.9e-27 94.1 0.2 1.9 1 1 0 1 1 1 1 YT521-B-like domain Glutaredoxin PF00462.24 KDO22078.1 - 8.5e-21 73.9 0.0 1.3e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF656 PF04920.12 KDO22078.1 - 0.031 14.2 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF656) SH3BGR PF04908.15 KDO22078.1 - 0.035 14.3 0.0 0.094 12.9 0.0 1.7 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Phosphodiest PF01663.22 KDO22079.1 - 8e-24 84.9 0.1 1.1e-23 84.5 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KDO22079.1 - 5e-07 29.4 0.1 2.1e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KDO22079.1 - 7.6e-05 22.2 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1501 PF07394.12 KDO22079.1 - 0.0085 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) PglZ PF08665.12 KDO22079.1 - 0.037 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Glyco_hydro_16 PF00722.21 KDO22079.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DUF229 PF02995.17 KDO22079.1 - 0.08 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Cu-oxidase PF00394.22 KDO22080.1 - 2.2e-37 128.6 0.3 1.9e-36 125.6 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KDO22080.1 - 1.3e-34 118.8 8.8 9.6e-34 116.0 0.6 4.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KDO22080.1 - 2e-30 105.3 13.8 2e-27 95.6 1.7 3.7 3 1 0 3 3 3 2 Multicopper oxidase Malt_amylase_C PF16657.5 KDO22080.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Metallophos PF00149.28 KDO22081.1 - 4e-32 112.4 0.0 1e-31 111.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KDO22081.1 - 3e-06 27.6 0.1 7e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO22081.1 - 7.7e-06 25.1 0.9 0.1 12.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO22081.1 - 2.7e-05 23.7 0.2 0.24 11.4 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain PAS PF00989.25 KDO22082.1 - 5.4e-120 393.6 3.8 1.6e-19 69.9 0.0 7.7 7 1 0 7 7 7 7 PAS fold PAS_4 PF08448.10 KDO22082.1 - 8.1e-78 257.8 0.0 8.3e-12 45.3 0.0 7.3 7 0 0 7 7 7 7 PAS fold PAS_9 PF13426.7 KDO22082.1 - 1.9e-66 220.8 13.3 6.8e-11 42.3 0.0 7.5 7 0 0 7 7 7 7 PAS domain PAS_3 PF08447.12 KDO22082.1 - 3.1e-34 117.1 0.0 2.5e-05 24.5 0.0 6.4 6 0 0 6 6 6 6 PAS fold HATPase_c PF02518.26 KDO22082.1 - 1.9e-26 92.8 0.1 4.2e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KDO22082.1 - 2.4e-23 81.7 1.1 3.9e-05 23.6 0.0 6.9 7 0 0 7 7 7 5 PAS domain Response_reg PF00072.24 KDO22082.1 - 3.5e-22 78.7 0.0 8.9e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KDO22082.1 - 1e-16 60.7 0.0 2.8e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 KDO22082.1 - 5e-10 39.9 6.6 0.014 16.0 0.0 6.0 6 0 0 6 6 6 2 PAS domain Hpt PF01627.23 KDO22082.1 - 4.1e-08 33.4 0.1 1.1e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 KDO22082.1 - 9.6e-08 32.2 10.9 0.59 10.3 0.2 8.0 6 4 0 6 6 6 2 PAS fold DUF5588 PF17826.1 KDO22082.1 - 0.026 13.4 2.5 5.8 5.7 0.0 4.1 5 0 0 5 5 5 0 Family of unknown function (DUF5588) DUF3189 PF11385.8 KDO22082.1 - 0.073 12.9 0.9 14 5.5 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3189) YukC PF10140.9 KDO22083.1 - 0.0019 17.1 0.0 0.002 17.0 0.0 1.0 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Sec16_C PF12931.7 KDO22084.1 - 3e-49 168.3 0.0 4.2e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KDO22084.1 - 2.4e-13 50.7 0.0 1.6e-12 48.1 0.0 2.3 1 1 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF4164 PF13747.6 KDO22084.1 - 0.3 11.4 0.5 0.49 10.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CsgF PF10614.9 KDO22084.1 - 0.31 11.3 12.2 1.3e+02 2.7 0.1 6.5 6 0 0 6 6 6 0 Type VIII secretion system (T8SS), CsgF protein RraA-like PF03737.15 KDO22085.1 - 9e-43 146.0 0.8 1.2e-42 145.6 0.8 1.1 1 0 0 1 1 1 1 Aldolase/RraA Lactamase_B_2 PF12706.7 KDO22086.1 - 3e-15 56.3 0.0 3.5e-07 30.0 0.0 2.9 2 2 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO22086.1 - 6.5e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MHB PF16525.5 KDO22086.1 - 0.0071 16.6 0.3 1.8 8.9 0.0 3.1 3 0 0 3 3 3 1 Haemophore, haem-binding Myb_DNA-binding PF00249.31 KDO22087.1 - 2.8e-33 113.8 12.9 5.4e-12 45.7 1.5 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO22087.1 - 1.8e-30 104.9 3.7 3.3e-15 56.1 0.1 3.1 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 KDO22087.1 - 5.3e-06 26.4 0.0 0.041 13.9 0.0 3.1 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 KDO22087.1 - 0.0046 17.3 7.1 0.77 10.2 0.4 3.4 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KDO22087.1 - 0.018 15.3 7.6 13 6.2 0.0 3.2 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 KDO22087.1 - 0.047 13.6 0.0 2.6 8.0 0.0 2.6 1 1 2 3 3 3 0 Myb DNA-binding like ubiquitin PF00240.23 KDO22088.1 - 1.1e-33 114.8 0.4 1.1e-33 114.8 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KDO22088.1 - 7.5e-27 93.2 2.3 7.5e-27 93.2 2.3 2.2 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KDO22088.1 - 1.5e-15 56.8 1.6 1.9e-15 56.5 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO22088.1 - 7.5e-06 26.3 0.3 0.00013 22.4 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO22088.1 - 0.00035 20.6 0.3 0.00081 19.5 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO22088.1 - 0.0079 16.7 0.6 0.011 16.3 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KDO22088.1 - 0.009 16.3 1.1 0.017 15.5 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KDO22088.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 KDO22088.1 - 0.034 14.4 0.8 0.055 13.7 0.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 KDO22088.1 - 0.49 10.5 3.1 9.1 6.4 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin-like domain MORN PF02493.20 KDO22090.1 - 1.5e-92 298.2 95.3 2e-07 30.5 0.1 24.5 24 1 0 24 24 24 22 MORN repeat NT-C2 PF10358.9 KDO22091.1 - 4.9e-09 36.0 0.0 1.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF5082 PF16888.5 KDO22091.1 - 0.0004 20.6 1.2 0.0004 20.6 1.2 6.1 3 3 3 6 6 6 2 Domain of unknown function (DUF5082) Fez1 PF06818.15 KDO22091.1 - 0.0025 18.3 67.5 0.04 14.4 12.1 4.4 2 1 2 4 4 4 1 Fez1 Spc7 PF08317.11 KDO22091.1 - 0.0025 16.7 11.7 0.0025 16.7 11.7 5.0 2 1 3 5 5 5 1 Spc7 kinetochore protein LOH1CR12 PF10158.9 KDO22091.1 - 0.0043 17.1 0.3 0.0043 17.1 0.3 3.7 3 2 1 4 4 4 1 Tumour suppressor protein TSC22 PF01166.18 KDO22091.1 - 0.0096 16.2 1.7 0.0096 16.2 1.7 8.1 9 1 1 10 10 8 1 TSC-22/dip/bun family CtIP_N PF10482.9 KDO22091.1 - 0.015 15.3 6.3 0.015 15.3 6.3 5.5 4 2 2 6 6 5 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.8 KDO22091.1 - 0.1 12.7 81.9 0.23 11.5 12.5 7.3 3 3 4 7 7 7 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 KDO22091.1 - 0.11 12.4 67.2 0.28 11.0 11.5 4.3 3 2 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KDO22091.1 - 0.16 12.2 92.0 3.4 7.9 14.4 6.1 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KDO22091.1 - 0.37 10.1 61.9 0.15 11.4 15.3 5.0 3 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding WD40_alt PF14077.6 KDO22091.1 - 0.48 10.3 11.7 0.92 9.4 0.1 5.1 5 0 0 5 5 5 0 Alternative WD40 repeat motif GIT_CC PF16559.5 KDO22091.1 - 1.1 9.2 41.6 0.13 12.1 1.1 8.3 7 2 1 8 8 8 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 KDO22091.1 - 1.2 9.3 44.3 1.6 8.9 9.2 4.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 KDO22091.1 - 1.4 8.8 64.1 2.3 8.1 0.1 9.8 9 1 1 10 10 10 0 Septum formation initiator HRDC PF00570.23 KDO22091.1 - 1.6 8.8 5.4 3.1 7.8 0.1 3.4 3 0 0 3 3 3 0 HRDC domain TMF_TATA_bd PF12325.8 KDO22091.1 - 2.6 8.3 70.8 0.044 14.0 5.8 8.5 3 3 6 9 9 9 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 KDO22091.1 - 3.3 8.1 63.2 1.3 9.5 7.8 7.0 4 2 3 7 7 7 0 Domain of unknown function (DUF4200) Shugoshin_N PF07558.11 KDO22091.1 - 5.1 7.1 11.3 2.8 7.9 0.1 4.3 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region TolA_bind_tri PF16331.5 KDO22091.1 - 5.5 7.2 57.4 0.95 9.6 6.4 8.7 6 2 3 9 9 9 0 TolA binding protein trimerisation DUF1811 PF08838.10 KDO22091.1 - 7.5 6.9 20.3 29 5.0 0.7 5.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1811) DUF3584 PF12128.8 KDO22091.1 - 8.5 3.7 71.1 0.13 9.7 17.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) C2 PF00168.30 KDO22092.1 - 1e-17 64.3 0.0 2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Isochorismatase PF00857.20 KDO22094.1 - 2.7e-06 27.7 0.8 0.00036 20.7 0.8 2.9 1 1 0 1 1 1 1 Isochorismatase family TIP49 PF06068.13 KDO22095.1 - 5.5e-146 486.3 9.1 2e-145 484.4 4.6 2.5 2 1 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 KDO22095.1 - 4.2e-25 87.7 0.9 4.2e-25 87.7 0.9 2.0 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 KDO22095.1 - 5.1e-09 36.7 3.7 1.6e-06 28.6 0.1 3.3 3 1 1 4 4 4 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO22095.1 - 3.8e-07 30.0 0.2 0.00025 20.8 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO22095.1 - 1.9e-06 27.9 0.1 0.00076 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 KDO22095.1 - 2.2e-06 27.2 0.1 3.9e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KDO22095.1 - 5.6e-06 26.7 0.0 0.016 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KDO22095.1 - 8.5e-05 23.0 0.5 0.00033 21.1 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KDO22095.1 - 0.00028 20.3 0.7 0.0083 15.5 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KDO22095.1 - 0.00043 20.6 1.2 0.0033 17.7 1.2 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KDO22095.1 - 0.00046 20.1 0.0 0.00086 19.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KDO22095.1 - 0.00072 19.2 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KDO22095.1 - 0.0015 18.3 0.1 0.67 9.6 0.1 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 KDO22095.1 - 0.0067 15.8 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 KDO22095.1 - 0.014 15.4 0.2 0.038 14.0 0.2 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KDO22095.1 - 0.015 15.0 0.8 0.26 11.0 0.3 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO22095.1 - 0.02 15.4 0.2 0.21 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KDO22095.1 - 0.021 14.1 0.3 0.041 13.2 0.3 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KDO22095.1 - 0.022 14.3 0.1 0.092 12.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KDO22095.1 - 0.056 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KDO22095.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KDO22095.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KDO22095.1 - 0.086 12.8 0.2 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KDO22095.1 - 0.098 12.7 0.0 0.72 9.9 0.3 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 KDO22095.1 - 0.12 12.8 0.5 0.2 12.1 0.5 1.4 1 1 0 1 1 1 0 AAA domain DUF2723 PF11028.8 KDO22096.1 - 3e-23 82.6 7.4 3e-23 82.6 7.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 KDO22096.1 - 0.0038 17.5 15.8 0.0038 17.5 15.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase BaxI_1 PF12811.7 KDO22096.1 - 2.3 7.7 9.4 0.16 11.5 4.1 1.9 2 0 0 2 2 2 0 Bax inhibitor 1 like Wzy_C PF04932.15 KDO22096.1 - 2.5 7.7 10.7 19 4.8 1.7 3.8 4 0 0 4 4 4 0 O-Antigen ligase HTH_Tnp_Tc5 PF03221.16 KDO22097.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain TRAF6_Z2 PF18048.1 KDO22097.1 - 7.6 6.7 7.5 13 5.9 7.5 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 FlaC_arch PF05377.11 KDO22099.1 - 0.19 12.1 0.0 0.54 10.7 0.0 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2867 PF11066.8 KDO22101.1 - 0.00073 19.9 0.2 0.00094 19.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) Glutaredoxin2_C PF04399.13 KDO22102.1 - 5.6e-48 162.1 0.0 7.3e-48 161.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 KDO22102.1 - 2.5e-11 43.8 0.0 5.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO22102.1 - 2.6e-09 37.2 0.0 1.1e-07 32.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO22102.1 - 0.015 15.6 0.0 0.051 13.9 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KDO22102.1 - 0.017 15.3 0.0 0.057 13.6 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.6 KDO22102.1 - 0.018 15.3 0.1 0.1 12.8 0.1 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mannosyl_trans3 PF11051.8 KDO22103.1 - 0.00011 21.7 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KDO22103.1 - 0.0037 16.9 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 MG2 PF01835.19 KDO22103.1 - 0.026 14.9 0.1 11 6.6 0.0 2.3 2 0 0 2 2 2 0 MG2 domain CLPTM1 PF05602.12 KDO22105.1 - 1.6e-128 429.4 0.3 1.9e-128 429.2 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) TMEM208_SND2 PF05620.11 KDO22105.1 - 0.00039 20.3 2.9 0.053 13.3 0.0 2.7 1 1 1 2 2 2 2 SRP-independent targeting protein 2/TMEM208 PQ-loop PF04193.14 KDO22105.1 - 0.00053 19.7 2.2 0.024 14.4 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat Nop53 PF07767.11 KDO22105.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) IQ PF00612.27 KDO22106.1 - 0.0023 17.6 2.2 0.0059 16.3 2.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif MIT PF04212.18 KDO22107.1 - 0.00031 20.8 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DPBB_1 PF03330.18 KDO22108.1 - 1.6e-07 31.5 0.2 5.6e-07 29.8 0.2 1.9 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KDO22108.1 - 0.018 15.1 0.2 0.13 12.3 0.0 2.5 3 1 0 3 3 3 0 Pollen allergen Lipocalin_5 PF13924.6 KDO22108.1 - 0.025 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipocalin-like domain PDZ PF00595.24 KDO22109.1 - 4e-06 27.1 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KDO22109.1 - 1.5e-05 24.8 0.0 0.056 13.3 0.1 2.7 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO22109.1 - 0.00067 19.9 0.0 0.63 10.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KDO22110.1 - 9.9e-13 47.7 0.0 1.7e-05 24.6 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KDO22110.1 - 1.4e-10 41.4 0.0 3.6e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain zf-RRN7 PF11781.8 KDO22110.1 - 0.0027 17.3 2.8 0.005 16.5 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkinase PF00069.25 KDO22112.1 - 1.8e-58 198.0 0.0 2.8e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO22112.1 - 5.4e-49 164.2 0.4 1.4e-17 63.6 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO22112.1 - 3e-29 102.1 0.0 4.6e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L18_c PF14204.6 KDO22112.1 - 0.013 16.4 0.1 0.027 15.4 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region MFS_1_like PF12832.7 KDO22113.1 - 1.8e-60 204.9 24.8 3.1e-60 204.1 24.8 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO22113.1 - 9.8e-17 60.9 39.6 1.1e-09 37.8 19.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO22113.1 - 3.9e-12 45.9 22.5 5.2e-12 45.5 22.5 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO22113.1 - 3e-08 32.9 20.1 2.1e-07 30.1 20.1 2.2 1 1 0 1 1 1 1 LacY proton/sugar symporter PPR_2 PF13041.6 KDO22114.1 - 4.6e-22 77.9 1.2 2.7e-12 46.7 0.2 4.8 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 KDO22114.1 - 2e-09 37.0 6.5 2.2e-06 27.5 0.1 3.9 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KDO22114.1 - 3.6e-09 36.6 0.0 0.00071 19.6 0.0 3.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KDO22114.1 - 8.6e-09 35.1 0.1 0.017 14.5 0.0 3.9 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KDO22114.1 - 7.5e-07 28.7 1.0 0.039 13.7 0.1 3.8 4 0 0 4 4 4 2 PPR repeat TPR_12 PF13424.6 KDO22114.1 - 0.22 11.8 1.8 4.2 7.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.23 KDO22115.1 - 1.1e-97 327.0 0.0 1.8e-97 326.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO22115.1 - 3.7e-24 85.3 0.0 7.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4140 PF13600.6 KDO22115.1 - 0.32 11.5 14.0 1.6 9.2 3.8 3.8 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) PHD PF00628.29 KDO22115.1 - 0.39 10.6 13.4 0.055 13.4 9.3 1.7 2 0 0 2 2 2 0 PHD-finger Tup_N PF08581.10 KDO22115.1 - 3.7 7.9 6.7 7.3 7.0 1.8 2.7 1 1 1 2 2 2 0 Tup N-terminal Golgin_A5 PF09787.9 KDO22115.1 - 6.7 6.1 17.2 0.14 11.6 5.5 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 FlxA PF14282.6 KDO22115.1 - 8.7 6.4 14.1 8.6 6.4 5.7 2.9 3 0 0 3 3 3 0 FlxA-like protein LRR_6 PF13516.6 KDO22116.1 - 3.8e-16 57.7 19.1 0.033 14.2 0.3 8.3 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 KDO22116.1 - 7.4e-07 29.4 8.8 0.0088 16.4 0.0 4.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO22116.1 - 6.7e-05 22.9 2.1 38 5.4 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO22116.1 - 0.0005 19.8 7.5 1.1 9.1 0.1 4.2 3 1 0 3 3 3 2 Leucine rich repeat DUF4476 PF14771.6 KDO22116.1 - 0.0076 16.5 0.0 0.076 13.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) WW PF00397.26 KDO22118.1 - 2.6e-27 94.6 20.7 9.7e-07 28.8 2.1 4.4 4 0 0 4 4 4 4 WW domain Hydrolase_2 PF07486.12 KDO22118.1 - 1.7e-05 25.6 6.3 1.3 9.9 0.0 4.3 2 1 1 4 4 4 2 Cell Wall Hydrolase PolC_DP2 PF03833.13 KDO22118.1 - 0.00028 18.9 0.2 0.00046 18.2 0.1 1.3 1 1 0 1 1 1 1 DNA polymerase II large subunit DP2 DUF4585 PF15232.6 KDO22118.1 - 0.0016 18.5 0.3 29 4.8 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4585) IQ PF00612.27 KDO22118.1 - 0.018 14.8 2.1 0.018 14.8 2.1 5.5 5 0 0 5 5 5 0 IQ calmodulin-binding motif OCRE PF17780.1 KDO22118.1 - 0.56 10.3 11.7 7.5 6.7 0.2 4.3 5 0 0 5 5 5 0 OCRE domain ADH_zinc_N PF00107.26 KDO22119.1 - 1.8e-20 73.2 0.0 4.4e-20 72.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO22119.1 - 4e-19 68.5 0.7 8e-19 67.5 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KDO22119.1 - 0.0036 16.6 0.2 0.0063 15.8 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KDO22119.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rep_fac-A_C PF08646.10 KDO22120.1 - 8.4e-43 145.6 1.4 1.8e-42 144.6 1.4 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KDO22120.1 - 1e-28 99.1 0.0 5.7e-27 93.5 0.1 2.3 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KDO22120.1 - 2.3e-23 82.1 0.0 5.3e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KDO22120.1 - 6.5e-12 45.3 0.2 5e-08 32.8 0.0 3.6 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KDO22120.1 - 0.0019 18.0 0.3 0.92 9.2 0.1 2.2 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 KDO22120.1 - 0.044 12.2 0.1 0.064 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF2039 PF10217.9 KDO22120.1 - 0.15 12.4 5.4 0.27 11.6 5.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Cuticle_3 PF11018.8 KDO22120.1 - 0.25 11.6 14.4 0.51 10.5 14.4 1.4 1 0 0 1 1 1 0 Pupal cuticle protein C1 DZR PF12773.7 KDO22120.1 - 0.54 10.3 6.1 1.1 9.3 6.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KDO22120.1 - 0.86 9.6 9.7 0.36 10.8 7.1 1.7 2 0 0 2 2 2 0 zinc-ribbons zf_UBZ PF18439.1 KDO22120.1 - 7.5 6.2 6.0 27 4.5 0.7 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger LRR_6 PF13516.6 KDO22121.1 - 2.3e-10 39.6 12.9 0.099 12.7 0.0 6.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 KDO22121.1 - 0.0043 17.4 6.9 17 6.4 0.1 5.5 5 1 0 5 5 5 1 Leucine Rich Repeat PBS_linker_poly PF00427.21 KDO22121.1 - 0.21 11.6 0.1 0.4 10.7 0.1 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide p25-alpha PF05517.12 KDO22121.1 - 0.26 11.5 0.0 0.53 10.4 0.0 1.4 1 0 0 1 1 1 0 p25-alpha Trp_oprn_chp PF09534.10 KDO22122.1 - 0.018 14.9 3.9 0.018 14.9 3.9 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DIM1 PF02966.16 KDO22123.1 - 7.3e-48 161.7 0.1 8.5e-48 161.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KDO22123.1 - 0.0026 17.7 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TPR_2 PF07719.17 KDO22124.1 - 2.3e-26 89.7 22.8 1.1e-05 25.2 0.4 10.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22124.1 - 2.2e-23 81.1 23.1 8e-07 28.6 0.3 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO22124.1 - 1.1e-21 76.2 11.4 3.7e-09 36.1 0.1 7.4 9 0 0 9 9 9 3 TPR repeat TPR_9 PF13371.6 KDO22124.1 - 2.1e-20 72.7 12.4 4.7e-05 23.4 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22124.1 - 3.2e-18 64.3 6.5 0.0086 16.2 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22124.1 - 2.3e-12 46.6 15.7 0.63 11.0 0.0 10.1 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22124.1 - 8.8e-10 38.7 19.8 0.0062 16.8 1.7 7.6 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KDO22124.1 - 7.3e-09 36.1 14.6 0.0014 19.3 0.1 6.4 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22124.1 - 8.5e-09 34.8 6.3 0.13 12.4 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KDO22124.1 - 5.5e-07 29.1 4.9 4.9 6.3 0.1 5.9 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO22124.1 - 0.00024 21.3 7.5 5.4 7.6 0.0 6.5 5 3 2 7 7 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KDO22124.1 - 0.00034 20.4 1.8 0.24 11.1 0.2 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 KDO22124.1 - 0.002 18.6 14.8 14 6.3 0.0 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO22124.1 - 0.0026 18.3 4.6 3.8 8.4 0.1 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KDO22124.1 - 0.004 16.6 0.1 1.8 7.9 0.0 2.6 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_MalT PF17874.1 KDO22124.1 - 0.01 15.3 1.4 0.097 12.0 0.7 2.9 4 0 0 4 4 4 0 MalT-like TPR region RPN7 PF10602.9 KDO22124.1 - 0.019 14.7 4.4 11 5.6 0.1 4.0 3 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF2333 PF10095.9 KDO22124.1 - 0.043 12.8 0.1 7 5.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Gamma_PGA_hydro PF05908.11 KDO22124.1 - 0.049 13.0 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase ANAPC3 PF12895.7 KDO22124.1 - 0.056 13.7 16.1 0.67 10.2 0.3 4.8 3 2 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Apc13p PF05839.11 KDO22124.1 - 0.06 13.5 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Apc13p protein TPR_10 PF13374.6 KDO22124.1 - 3.8 7.5 8.4 58 3.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PX PF00787.24 KDO22125.1 - 0.00036 20.5 0.1 0.00073 19.5 0.1 1.5 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 KDO22128.1 - 6.1e-58 196.3 0.0 1.6e-57 194.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22128.1 - 1.5e-32 112.9 0.0 5.4e-32 111.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO22128.1 - 6e-05 22.0 0.1 8.1e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO22128.1 - 0.00047 19.6 0.0 0.0012 18.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO22128.1 - 0.017 14.5 0.0 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO22128.1 - 0.022 14.7 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO22128.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KDO22128.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KDO22128.1 - 0.71 8.9 2.2 4 6.4 0.3 2.1 1 1 1 2 2 2 0 Seadornavirus VP7 Actin PF00022.19 KDO22129.1 - 9.4e-130 432.9 0.0 5.1e-129 430.4 0.0 1.8 1 1 0 1 1 1 1 Actin Fumble PF03630.14 KDO22130.1 - 7.5e-117 390.2 2.4 8.7e-117 390.0 2.4 1.0 1 0 0 1 1 1 1 Fumble RTC PF01137.21 KDO22133.1 - 3.1e-56 190.0 0.0 3.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KDO22133.1 - 3.5e-35 120.6 0.0 6.2e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain FGF-BP1 PF06473.12 KDO22134.1 - 0.079 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TAF4 PF05236.14 KDO22134.1 - 1.9 8.2 5.9 3.5 7.3 5.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TIG PF01833.24 KDO22135.1 - 6.7e-198 641.4 258.3 3.4e-10 39.9 1.6 50.2 49 0 0 49 49 49 42 IPT/TIG domain TIG_plexin PF17960.1 KDO22135.1 - 1.2e-30 105.3 91.4 0.098 12.7 0.0 38.5 45 0 0 45 45 45 13 TIG domain Anth_Ig PF05587.13 KDO22135.1 - 1.6e-14 54.0 16.0 0.27 11.6 0.0 14.2 14 1 1 15 15 15 3 Anthrax receptor extracellular domain Ephrin_rec_like PF07699.13 KDO22135.1 - 0.0016 18.1 2.4 0.0016 18.1 2.4 8.0 6 1 1 7 7 7 3 Putative ephrin-receptor like DBB PF14545.6 KDO22135.1 - 0.032 14.2 7.9 2.8 7.9 0.0 6.3 7 0 0 7 7 7 0 Dof, BCAP, and BANK (DBB) motif, Big_9 PF17963.1 KDO22136.1 - 0.011 16.4 3.7 1.2 9.9 0.0 4.3 4 0 0 4 4 4 0 Bacterial Ig domain CH_2 PF06294.11 KDO22137.1 - 7.9e-36 122.1 0.8 3.5e-35 120.0 0.0 2.1 2 1 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KDO22137.1 - 1.7e-17 63.0 0.0 3.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain DUF641 PF04859.12 KDO22137.1 - 0.0022 18.4 2.7 0.0028 18.0 1.3 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) CH PF00307.31 KDO22137.1 - 0.0029 17.8 0.2 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain PKcGMP_CC PF16808.5 KDO22137.1 - 0.06 13.2 7.3 3.8 7.4 0.8 3.2 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 KDO22137.1 - 0.065 13.3 6.6 0.15 12.2 6.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KDO22137.1 - 0.13 12.7 3.9 0.092 13.2 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 BST2 PF16716.5 KDO22137.1 - 2.8 8.6 9.8 4.4 8.0 7.5 2.2 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Orn_Arg_deC_N PF02784.16 KDO22138.1 - 1.4e-16 60.7 0.0 1.2e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain TcfC PF16967.5 KDO22138.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 E-set like domain Glyco_transf_8 PF01501.20 KDO22139.1 - 2.2e-14 53.7 0.0 2.9e-14 53.3 0.0 1.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KDO22139.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KDO22139.1 - 0.004 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Kazal_2 PF07648.15 KDO22140.1 - 7.9e-48 160.4 51.8 3.5e-12 46.3 1.7 5.2 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO22140.1 - 1.2e-44 150.1 50.0 2.2e-11 43.6 2.5 5.3 4 1 1 5 5 5 5 Kazal-type serine protease inhibitor domain SelR PF01641.18 KDO22141.1 - 1.5e-46 157.4 0.0 3.2e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 SelR domain DOT1 PF08123.13 KDO22141.1 - 4.2e-12 46.0 0.0 6.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 KDO22141.1 - 0.00091 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 KDO22141.1 - 0.0031 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO22141.1 - 0.051 14.2 0.0 0.31 11.7 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 KDO22141.1 - 0.14 12.9 0.0 0.57 10.9 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KDO22141.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 5_nucleotid_C PF02872.18 KDO22143.1 - 2.8e-18 66.6 0.0 5.7e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KDO22143.1 - 6.7e-09 36.5 0.0 1.8e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase FYVE PF01363.21 KDO22144.1 - 0.0021 18.1 8.5 0.0053 16.9 8.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 KDO22144.1 - 0.016 14.9 5.2 0.029 14.1 5.2 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DZR PF12773.7 KDO22144.1 - 0.14 12.2 10.5 0.36 10.9 9.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 KDO22144.1 - 0.64 9.9 11.6 0.19 11.6 4.6 2.8 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KDO22144.1 - 1.4 9.0 11.2 56 3.8 11.2 2.7 1 1 0 1 1 1 0 zinc-ribbons zf-B_box PF00643.24 KDO22144.1 - 3.8 7.7 13.8 1.1 9.4 7.9 2.8 2 1 0 2 2 2 0 B-box zinc finger Pkinase PF00069.25 KDO22145.1 - 2.1e-50 171.6 0.0 9.1e-38 130.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22145.1 - 1e-28 100.4 0.0 1.2e-24 87.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO22145.1 - 2e-05 24.1 0.0 0.1 11.9 0.0 2.7 2 1 0 3 3 3 2 Kinase-like Kdo PF06293.14 KDO22145.1 - 6.3e-05 22.4 0.0 8.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO22145.1 - 0.041 12.9 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KDO22145.1 - 0.042 13.8 0.1 0.095 12.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO22147.1 - 0.092 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain ABC2_membrane_3 PF12698.7 KDO22148.1 - 2e-08 33.8 4.3 6.9e-06 25.4 2.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein Pkinase PF00069.25 KDO22149.1 - 3e-44 151.4 0.0 3.7e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22149.1 - 2.4e-26 92.6 0.0 3e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO22149.1 - 5.6e-06 25.9 0.0 7.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO22149.1 - 7.3e-05 22.2 0.0 8.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO22149.1 - 0.039 13.0 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KDO22149.1 - 0.22 10.2 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC2_membrane_3 PF12698.7 KDO22150.1 - 2.5e-05 23.6 0.8 3e-05 23.3 0.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Globin PF00042.22 KDO22152.1 - 0.075 13.6 0.3 0.29 11.7 0.3 1.9 1 1 0 1 1 1 0 Globin Pkinase_Tyr PF07714.17 KDO22153.1 - 2e-20 73.2 0.0 2.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22153.1 - 8e-18 64.7 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KDO22153.1 - 7.5e-09 36.0 0.8 2.3e-06 28.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22153.1 - 1.6e-06 28.2 0.2 5.8e-06 26.5 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22153.1 - 2.4e-06 28.0 0.2 5.9e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22153.1 - 0.0002 21.5 1.1 0.02 15.4 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KDO22153.1 - 0.093 13.2 1.0 2.2 8.9 0.2 2.8 2 0 0 2 2 2 0 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO22154.1 - 1.1e-38 133.0 0.0 1.4e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22154.1 - 4e-38 131.3 0.0 5.4e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO22154.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO22154.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_2 PF12796.7 KDO22155.1 - 1.2e-12 48.3 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22155.1 - 5.7e-11 41.6 0.3 0.011 16.1 0.0 3.3 2 1 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO22155.1 - 9.3e-11 41.7 0.4 1.4e-05 25.3 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO22155.1 - 2.2e-10 40.8 0.2 7.8e-05 23.1 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22155.1 - 4.7e-09 36.3 0.1 0.00021 21.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO22156.1 - 5.3e-38 130.9 0.0 3.8e-37 128.1 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22156.1 - 9.5e-32 110.3 0.0 9.6e-31 107.0 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO22156.1 - 2.4e-25 88.6 6.8 1.5e-09 38.2 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22156.1 - 7.1e-25 87.4 11.3 1.1e-09 38.7 0.7 3.7 1 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22156.1 - 2.1e-18 64.5 12.8 0.0043 17.4 0.1 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KDO22156.1 - 3.6e-12 46.3 15.3 0.1 12.9 0.1 6.5 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO22156.1 - 3.6e-07 30.3 27.0 0.075 13.5 0.1 7.5 8 0 0 8 8 8 4 Ankyrin repeat Kdo PF06293.14 KDO22156.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO22156.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PKD_channel PF08016.12 KDO22157.1 - 3.3e-21 75.5 12.9 3.1e-14 52.5 9.9 3.1 3 0 0 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 KDO22157.1 - 8.6e-07 28.4 9.7 2e-06 27.2 9.7 1.6 1 0 0 1 1 1 1 Ion transport protein TMEM40 PF15817.5 KDO22157.1 - 0.0013 18.5 1.1 0.011 15.4 0.2 2.4 2 0 0 2 2 2 1 Transmembrane protein 40 family Phenyl_P_gamma PF09662.10 KDO22157.1 - 0.13 12.5 0.0 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) EI24 PF07264.11 KDO22158.1 - 1.4e-17 64.5 12.0 1.7e-17 64.2 12.0 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3980 PF13140.6 KDO22158.1 - 0.027 14.9 1.0 0.027 14.9 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) DUF996 PF06195.13 KDO22158.1 - 0.26 11.6 7.5 0.043 14.1 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF3938 PF13074.6 KDO22158.1 - 1.3 9.3 6.5 0.58 10.4 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) AMP-binding_C PF13193.6 KDO22159.1 - 2.1e-06 28.6 0.3 2.1e-06 28.6 0.3 2.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO22159.1 - 0.017 13.7 0.1 0.025 13.2 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Aminotran_5 PF00266.19 KDO22160.1 - 3.6e-34 118.3 0.0 5.5e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 KDO22160.1 - 1.5e-16 60.6 0.0 2.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Ank_2 PF12796.7 KDO22161.1 - 8.7e-51 170.4 9.0 4.2e-15 56.1 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22161.1 - 2.6e-40 136.3 9.6 3.4e-10 40.2 0.1 8.0 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22161.1 - 3.6e-35 116.0 12.5 2.2e-05 24.5 0.0 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KDO22161.1 - 4.4e-32 109.1 20.0 2.2e-05 24.7 0.1 8.7 9 1 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KDO22161.1 - 5e-30 103.2 20.3 1.7e-06 28.2 0.1 8.2 5 3 4 9 9 9 7 Ankyrin repeats (many copies) DUF2428 PF10350.9 KDO22162.1 - 4.7e-45 154.0 0.3 1.1e-44 152.8 0.3 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) SYCE1 PF15233.6 KDO22163.1 - 0.0016 18.5 2.3 0.0016 18.5 2.3 6.3 3 3 3 6 6 4 1 Synaptonemal complex central element protein 1 CENP-F_leu_zip PF10473.9 KDO22163.1 - 0.0038 17.3 10.3 0.0038 17.3 10.3 6.9 3 3 2 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 KDO22163.1 - 0.0047 16.3 12.6 0.0047 16.3 12.6 5.3 3 3 1 4 4 3 2 Tropomyosin KASH_CCD PF14662.6 KDO22163.1 - 0.0089 15.9 10.9 0.0089 15.9 10.9 6.1 3 2 2 6 6 6 2 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 KDO22163.1 - 0.013 15.8 1.2 0.013 15.8 1.2 5.9 6 0 0 6 6 6 0 Homeobox associated leucine zipper WES_acyltransf PF03007.16 KDO22163.1 - 0.015 15.1 1.1 0.015 15.1 1.1 4.4 3 1 2 5 5 5 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Spc7 PF08317.11 KDO22163.1 - 0.048 12.5 64.0 0.054 12.4 1.0 5.4 3 2 2 5 5 5 0 Spc7 kinetochore protein Aida_N PF08910.10 KDO22163.1 - 0.085 13.3 0.3 0.085 13.3 0.3 4.9 4 1 2 6 6 6 0 Aida N-terminus TolA_bind_tri PF16331.5 KDO22163.1 - 0.12 12.5 0.0 0.12 12.5 0.0 7.4 4 4 3 7 7 7 0 TolA binding protein trimerisation PKcGMP_CC PF16808.5 KDO22163.1 - 0.34 10.8 0.0 0.34 10.8 0.0 5.8 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlaC_arch PF05377.11 KDO22163.1 - 0.9 10.0 13.7 0.84 10.1 0.1 6.4 8 0 0 8 8 7 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 KDO22163.1 - 2.3 8.2 5.5 13 5.8 0.2 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4250 PF14056.6 KDO22163.1 - 3.9 7.5 13.0 12 5.9 0.2 5.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) DUF4279 PF14106.6 KDO22163.1 - 5.1 7.3 5.8 15 5.8 0.2 4.0 5 1 1 6 6 5 0 Domain of unknown function (DUF4279) UPF0640 PF15114.6 KDO22164.1 - 0.0024 17.7 0.6 0.0036 17.1 0.1 1.6 2 1 0 2 2 2 1 Uncharacterised protein family UPF0640 IQ PF00612.27 KDO22165.1 - 0.00016 21.2 0.8 0.00034 20.2 0.8 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1 PF07690.16 KDO22166.1 - 6.1e-05 22.1 38.8 0.00022 20.3 36.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2178 PF09946.9 KDO22166.1 - 0.043 14.0 0.0 0.043 14.0 0.0 2.6 4 0 0 4 4 4 0 Predicted membrane protein (DUF2178) FYVE PF01363.21 KDO22167.1 - 2.8e-30 104.2 28.3 1.5e-16 60.2 7.3 2.7 3 0 0 3 3 3 2 FYVE zinc finger FYVE_2 PF02318.16 KDO22167.1 - 0.021 15.1 20.1 0.25 11.6 4.7 2.6 2 1 0 2 2 2 0 FYVE-type zinc finger PLDc_2 PF13091.6 KDO22168.1 - 2e-12 47.1 0.0 1.9e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.22 KDO22168.1 - 5.8e-05 23.1 4.9 0.0003 20.8 1.1 2.9 2 1 0 2 2 2 1 Phospholipase D Active site motif PLDc_2 PF13091.6 KDO22169.1 - 1.7e-11 44.1 0.0 1.7e-10 40.9 0.0 2.3 2 1 0 2 2 2 1 PLD-like domain PLDc PF00614.22 KDO22169.1 - 0.013 15.6 3.4 0.24 11.7 0.5 3.1 2 1 0 2 2 2 0 Phospholipase D Active site motif MULE PF10551.9 KDO22170.1 - 4e-07 30.4 0.0 9.5e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 KDO22170.1 - 0.0055 16.7 0.1 0.02 14.9 0.1 1.9 1 1 1 2 2 2 1 MuDR family transposase SQS_PSY PF00494.19 KDO22171.1 - 0.084 12.4 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase PLDc_2 PF13091.6 KDO22172.1 - 1.9e-12 47.2 0.0 3.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 KDO22172.1 - 0.023 14.9 0.7 0.049 13.8 0.7 1.6 1 0 0 1 1 1 0 Phospholipase D Active site motif PLDc_2 PF13091.6 KDO22173.1 - 4.5e-11 42.8 0.0 1.9e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.22 KDO22173.1 - 0.00022 21.3 3.0 0.012 15.8 0.8 2.9 2 1 1 3 3 3 2 Phospholipase D Active site motif adh_short PF00106.25 KDO22174.1 - 1.1e-41 142.5 3.9 1.6e-41 141.9 3.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO22174.1 - 2.5e-33 115.6 2.4 4.2e-33 114.9 2.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO22174.1 - 4.6e-15 56.0 2.4 7.4e-15 55.3 2.4 1.3 1 0 0 1 1 1 1 KR domain DUF853 PF05872.12 KDO22174.1 - 0.11 11.0 1.2 0.17 10.5 1.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Kinesin PF00225.23 KDO22175.1 - 3.3e-116 387.9 0.0 3.3e-116 387.9 0.0 1.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO22175.1 - 2.7e-24 85.8 0.0 2.3e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Kinesin PF00225.23 KDO22176.1 - 8e-88 294.5 1.5 1.5e-87 293.7 1.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO22176.1 - 3.1e-20 72.6 1.6 1.6e-19 70.3 0.1 2.7 3 0 0 3 3 3 1 Microtubule binding AAA_7 PF12775.7 KDO22176.1 - 0.059 12.9 0.1 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PIEZO PF15917.5 KDO22176.1 - 0.13 11.7 4.4 0.36 10.3 4.4 1.7 1 0 0 1 1 1 0 Piezo Troponin PF00992.20 KDO22176.1 - 0.56 10.5 14.0 0.046 14.0 6.8 2.8 3 0 0 3 3 3 0 Troponin Rx_N PF18052.1 KDO22176.1 - 0.79 10.0 4.7 17 5.8 0.1 2.8 2 0 0 2 2 2 0 Rx N-terminal domain DASH_Duo1 PF08651.10 KDO22176.1 - 5.9 6.7 8.2 1.6 8.6 2.5 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 SpoIIE PF07228.12 KDO22177.1 - 6.3e-12 45.8 0.0 1.2e-11 44.9 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KDO22177.1 - 4.4e-06 26.5 0.0 0.0065 16.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KDO22177.1 - 0.01 15.5 0.2 0.044 13.4 0.2 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C Arm-DNA-bind_5 PF17293.2 KDO22178.1 - 0.36 11.3 2.3 0.5 10.8 0.3 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Noelin-1 PF12308.8 KDO22178.1 - 0.65 10.0 2.9 0.53 10.3 0.6 2.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein BST2 PF16716.5 KDO22178.1 - 3.1 8.5 10.6 0.39 11.3 0.8 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 LRR_6 PF13516.6 KDO22179.1 - 7.3e-09 35.0 8.8 0.0017 18.2 0.1 5.5 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KDO22179.1 - 0.00019 21.5 1.3 4.8 8.1 0.0 5.5 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 KDO22179.1 - 0.2 12.1 10.1 4.3 7.9 1.8 4.6 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) DHC_N2 PF08393.13 KDO22180.1 - 3.8e-71 240.3 0.0 1.1e-70 238.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 KDO22180.1 - 5.3e-20 71.7 6.3 9.9e-20 70.8 6.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 KDO22180.1 - 7.6e-18 64.6 1.5 1.7e-15 56.8 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 KDO22180.1 - 3.2e-17 62.6 0.0 4.5e-11 42.6 0.0 5.3 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_8 PF12780.7 KDO22180.1 - 1.9e-14 53.6 0.0 4.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 KDO22180.1 - 2.2e-06 27.8 0.0 6.3e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KDO22180.1 - 0.00011 22.7 9.8 0.18 12.2 0.0 6.5 5 1 0 6 6 6 1 AAA ATPase domain AAA PF00004.29 KDO22180.1 - 0.00016 22.1 0.0 11 6.4 0.0 4.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO22180.1 - 0.00036 21.1 0.5 3.2 8.3 0.0 3.9 3 0 0 3 3 3 2 AAA domain HBD PF18534.1 KDO22180.1 - 0.0065 16.6 0.0 0.21 11.7 0.0 2.8 2 0 0 2 2 2 1 Helical bundle domain AAA_29 PF13555.6 KDO22180.1 - 0.0068 16.1 0.0 1.4 8.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain SMC_N PF02463.19 KDO22180.1 - 0.038 13.4 0.0 0.25 10.7 0.0 2.3 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 KDO22180.1 - 0.051 13.6 0.2 7.1 6.6 0.2 3.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO22180.1 - 0.11 12.3 0.2 14 5.4 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KDO22180.1 - 0.13 12.6 0.0 46 4.5 0.0 3.7 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.15 KDO22180.1 - 0.16 11.9 0.5 1 9.2 0.0 2.5 3 0 0 3 3 3 0 Rad17 P-loop domain NTPase_1 PF03266.15 KDO22180.1 - 0.29 11.0 0.7 2.8 7.8 0.2 2.6 2 0 0 2 2 2 0 NTPase DUF3138 PF11336.8 KDO22180.1 - 2 7.0 6.6 4.3 5.8 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_28 PF13521.6 KDO22180.1 - 2.3 8.4 10.8 0.9 9.8 0.0 5.0 6 0 0 6 6 5 0 AAA domain SCHIP-1 PF10148.9 KDO22181.1 - 0.097 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 LPP PF04728.13 KDO22182.1 - 0.0045 17.3 1.4 2 8.8 0.4 2.2 2 0 0 2 2 2 2 Lipoprotein leucine-zipper zf-C4H2 PF10146.9 KDO22182.1 - 0.006 16.9 1.5 0.0078 16.6 1.5 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein ZapB PF06005.12 KDO22182.1 - 0.01 16.3 0.7 5.7 7.5 0.2 2.3 2 1 0 2 2 2 0 Cell division protein ZapB Syntaxin_2 PF14523.6 KDO22182.1 - 0.033 14.6 1.1 0.99 9.8 0.1 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DivIC PF04977.15 KDO22182.1 - 0.041 13.7 0.8 6.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator RNase_E_G PF10150.9 KDO22182.1 - 0.042 13.3 0.4 0.056 12.9 0.4 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family CtIP_N PF10482.9 KDO22182.1 - 0.051 13.6 0.7 0.3 11.1 0.1 2.1 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TSC22 PF01166.18 KDO22182.1 - 0.054 13.8 0.5 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF1192 PF06698.11 KDO22182.1 - 0.058 13.5 0.1 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Prefoldin PF02996.17 KDO22182.1 - 0.066 13.1 2.2 2 8.3 0.3 2.4 2 1 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KDO22182.1 - 0.085 13.5 0.4 11 6.7 0.0 2.5 2 1 0 2 2 2 0 SlyX DUF2443 PF10398.9 KDO22182.1 - 0.11 12.5 1.1 7.7 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) betaPIX_CC PF16523.5 KDO22182.1 - 0.11 12.3 4.8 2.1 8.2 0.5 2.5 1 1 2 3 3 3 0 betaPIX coiled coil DUF5082 PF16888.5 KDO22182.1 - 0.12 12.7 3.1 2.5 8.4 3.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) GIT_CC PF16559.5 KDO22182.1 - 0.12 12.3 2.4 8 6.4 0.1 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TTRAP PF14203.6 KDO22182.1 - 0.28 11.2 1.9 3.2 7.8 0.1 2.6 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein 2-oxoacid_dh PF00198.23 KDO22183.1 - 2.4e-54 184.2 0.0 3e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KDO22183.1 - 2.9e-18 65.5 0.5 6.4e-18 64.4 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KDO22183.1 - 2e-05 24.8 0.4 4.4e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KDO22183.1 - 0.0059 16.4 1.4 0.02 14.7 0.0 2.7 3 0 0 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 KDO22183.1 - 0.19 11.6 0.1 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein Methyltransf_16 PF10294.9 KDO22184.1 - 1.4e-19 70.5 0.0 2.9e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO22184.1 - 2.1e-05 24.1 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KDO22184.1 - 0.00035 20.1 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KDO22184.1 - 0.00061 19.7 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO22184.1 - 0.00099 19.8 0.0 0.0026 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KDO22184.1 - 0.045 13.5 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 KDO22184.1 - 0.046 13.5 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO22184.1 - 0.073 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C1 PF00112.23 KDO22185.1 - 0.00027 21.1 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1 PF00112.23 KDO22186.1 - 0.00021 21.5 0.3 0.05 13.7 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease TPR_21 PF09976.9 KDO22186.1 - 0.074 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Endosulfine PF04667.17 KDO22187.1 - 3.1e-05 24.0 0.0 3.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_C1 PF00112.23 KDO22188.1 - 7.4e-06 26.2 0.2 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_M3 PF01432.20 KDO22189.1 - 3.7e-127 425.4 0.0 4.8e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF4203 PF13886.6 KDO22190.1 - 6.5e-22 78.2 5.0 8.9e-22 77.7 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SR-25 PF10500.9 KDO22190.1 - 0.02 14.5 7.0 0.028 14.0 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP2 PF01569.21 KDO22191.1 - 4.8e-20 71.7 7.2 4.8e-20 71.7 7.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KDO22191.1 - 2.9e-05 23.9 10.9 0.0013 18.4 10.9 2.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KDO22191.1 - 0.003 18.0 1.3 0.003 18.0 1.3 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal AMP-binding PF00501.28 KDO22192.1 - 1.7e-40 138.9 0.2 1.4e-25 89.8 0.0 2.5 2 1 1 3 3 3 2 AMP-binding enzyme PQQ_3 PF13570.6 KDO22192.1 - 6.5e-28 96.4 15.8 2.8e-08 34.0 0.1 9.3 9 0 0 9 9 9 7 PQQ-like domain PQQ_2 PF13360.6 KDO22192.1 - 1.8e-20 73.5 0.7 1.1e-11 44.8 0.1 3.3 1 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 KDO22192.1 - 4.8e-13 48.3 0.6 9.8e-05 22.1 0.0 4.6 4 0 0 4 4 4 3 PQQ enzyme repeat PP-binding PF00550.25 KDO22192.1 - 1.8e-06 28.2 0.2 3.9e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site SUKH-4 PF14435.6 KDO22192.1 - 0.16 12.0 4.6 0.62 10.1 0.3 3.7 3 1 1 4 4 4 0 SUKH-4 immunity protein NTP_transferase PF00483.23 KDO22193.1 - 1.3e-23 83.9 0.0 2.7e-23 82.8 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KDO22193.1 - 8.8e-13 48.9 0.1 1e-12 48.7 0.1 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF5612 PF18462.1 KDO22193.1 - 0.00028 20.7 0.2 0.00051 19.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5612) IspD PF01128.19 KDO22193.1 - 0.0017 18.2 0.1 0.0024 17.7 0.1 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase baeRF_family2 PF18844.1 KDO22193.1 - 0.052 13.6 1.3 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 ATG16 PF08614.11 KDO22194.1 - 0.013 15.7 8.7 0.098 12.9 0.7 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 KDO22194.1 - 0.051 13.7 14.2 0.056 13.5 8.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper CENP-K PF11802.8 KDO22194.1 - 0.062 12.9 1.4 0.093 12.3 1.4 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Nmad5 PF18757.1 KDO22194.1 - 0.19 11.9 2.0 0.34 11.1 2.0 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 ORF11CD3 PF10549.9 KDO22194.1 - 0.35 11.0 1.8 2.2 8.5 0.8 2.6 3 0 0 3 3 3 0 ORF11CD3 domain PriC PF07445.12 KDO22194.1 - 0.53 10.2 6.8 2.9 7.8 0.4 2.1 2 0 0 2 2 2 0 Primosomal replication protein priC DivIC PF04977.15 KDO22194.1 - 1.4 8.7 6.1 3.6 7.4 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Pannexin_like PF12534.8 KDO22194.1 - 2.3 7.2 3.8 3.3 6.7 3.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 UPF0242 PF06785.11 KDO22194.1 - 2.5 8.2 4.9 4 7.5 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 KDO22194.1 - 3.3 7.9 14.3 3 8.0 8.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor polyprenyl_synt PF00348.17 KDO22195.1 - 2.7e-35 121.7 0.1 4e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase VWA PF00092.28 KDO22196.1 - 2.6e-15 57.1 0.0 4.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KDO22196.1 - 2.5e-10 40.9 0.6 8.6e-10 39.2 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KDO22196.1 - 7e-08 32.6 0.1 2.5e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF294_C PF10335.9 KDO22196.1 - 0.13 12.1 2.7 0.31 10.8 2.7 1.6 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Hydrolase_4 PF12146.8 KDO22197.1 - 9.7e-60 201.8 0.0 1.1e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO22197.1 - 1.2e-20 75.0 0.0 1.5e-20 74.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO22197.1 - 4.6e-16 59.2 0.0 6.5e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO22197.1 - 8.7e-13 48.2 0.0 5.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KDO22197.1 - 1.8e-06 27.7 0.0 0.0016 18.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KDO22197.1 - 0.0012 18.7 0.0 0.053 13.3 0.1 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KDO22197.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.9 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 KDO22197.1 - 0.0015 17.5 0.1 0.0027 16.7 0.1 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KDO22197.1 - 0.0092 15.8 0.0 2.2 8.0 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KDO22197.1 - 0.0096 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.11 KDO22197.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Chlorophyllase DUF3342 PF11822.8 KDO22198.1 - 1.2e-26 92.7 0.1 2.1e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 KDO22198.1 - 0.0008 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PROL5-SMR PF15621.6 KDO22198.1 - 0.034 14.7 0.9 0.1 13.1 0.9 1.8 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF5544 PF17698.1 KDO22198.1 - 0.042 14.0 4.0 0.091 12.9 3.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5544) Pkinase PF00069.25 KDO22199.1 - 3.6e-60 203.6 0.0 4.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22199.1 - 3.6e-47 160.8 0.0 5.1e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO22199.1 - 7.6e-07 28.7 0.1 4.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO22199.1 - 0.001 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HTH_Tnp_Mu_1 PF02316.16 KDO22199.1 - 0.064 13.4 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain Pkinase PF00069.25 KDO22200.1 - 4.4e-20 72.2 0.0 5.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22200.1 - 1.6e-12 47.3 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Acyl_transf_3 PF01757.22 KDO22201.1 - 3.7e-16 59.1 29.3 3.7e-16 59.1 29.3 2.7 2 1 1 3 3 3 1 Acyltransferase family Fig1 PF12351.8 KDO22201.1 - 1.6 8.7 5.0 16 5.4 0.2 2.9 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 PAP_assoc PF03828.19 KDO22202.1 - 7.1e-16 58.2 0.0 1.4e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KDO22202.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF2621 PF11084.8 KDO22202.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Ank_5 PF13857.6 KDO22209.1 - 3.4e-20 71.8 3.7 3.6e-10 39.9 0.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22209.1 - 6.9e-20 71.4 2.1 1.1e-10 42.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22209.1 - 7.1e-15 53.6 2.7 6.5e-06 26.1 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KDO22209.1 - 1.5e-14 53.6 4.5 0.00038 20.8 0.2 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KDO22209.1 - 1.1e-12 48.2 1.7 0.00017 22.1 0.1 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF1949 PF09186.11 KDO22209.1 - 0.12 12.2 0.3 1.5 8.7 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1949) XRCC4 PF06632.12 KDO22210.1 - 5.3e-07 28.8 0.0 6.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 UPF0561 PF10573.9 KDO22210.1 - 0.83 9.8 3.8 1.9 8.6 3.4 1.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 MRG PF05712.13 KDO22212.1 - 3.8e-26 91.6 0.1 5.2e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 MRG ParE-like_toxin PF15781.5 KDO22213.1 - 0.32 11.0 2.3 0.36 10.8 0.2 2.1 2 1 1 3 3 3 0 ParE-like toxin of type II bacterial toxin-antitoxin system Pox_Ag35 PF03286.14 KDO22213.1 - 0.62 9.8 16.7 0.87 9.3 16.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mitofilin PF09731.9 KDO22213.1 - 1.1 8.0 17.3 1.3 7.8 17.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIT PF04212.18 KDO22214.1 - 0.0034 17.4 1.1 0.0083 16.2 1.1 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Bacteriocin_IIc PF10439.9 KDO22214.1 - 0.0097 16.0 16.6 0.018 15.2 16.6 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.13 KDO22214.1 - 0.012 15.9 5.5 0.018 15.3 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) CwsA PF10814.8 KDO22214.1 - 0.1 12.7 0.4 0.1 12.7 0.4 2.4 2 2 0 2 2 2 0 Cell wall synthesis protein CwsA SKN1 PF03935.15 KDO22215.1 - 3.3e-60 203.9 23.7 1.2e-24 86.6 1.4 5.3 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) Trp_oprn_chp PF09534.10 KDO22215.1 - 0.09 12.6 0.1 0.33 10.7 0.1 1.9 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EB PF01683.18 KDO22215.1 - 0.11 12.8 4.9 0.098 13.0 2.3 2.3 2 0 0 2 2 2 0 EB module Sugar_tr PF00083.24 KDO22216.1 - 3.1e-39 135.1 29.7 4.2e-26 91.8 7.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO22216.1 - 2.7e-23 82.5 34.2 3.1e-18 65.8 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf70 PF17382.2 KDO22216.1 - 0.23 11.9 0.7 2.8 8.4 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized Ycf70-like Sugar_tr PF00083.24 KDO22217.1 - 4.2e-15 55.6 19.7 7.1e-13 48.2 16.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter CCSMST1 PF15013.6 KDO22217.1 - 0.081 13.1 0.2 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 CCSMST1 family Ycf70 PF17382.2 KDO22217.1 - 0.086 13.3 1.5 1.3 9.5 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized Ycf70-like Pkinase_Tyr PF07714.17 KDO22218.1 - 3e-30 105.4 0.0 3.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22218.1 - 6e-29 101.2 0.0 7.4e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO22218.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SKN1 PF03935.15 KDO22219.1 - 5.6e-61 206.5 19.3 5.1e-25 87.9 0.5 5.4 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO22219.1 - 0.0081 16.4 3.7 0.0086 16.4 1.3 2.3 2 0 0 2 2 2 1 EB module Pkinase PF00069.25 KDO22220.1 - 1.3e-33 116.5 0.0 1.8e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22220.1 - 3.1e-26 92.2 0.0 4.3e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO22220.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CBM_1 PF00734.18 KDO22221.1 - 1.9e-13 50.1 23.3 4.7e-09 36.1 9.3 4.5 4 1 1 5 5 5 2 Fungal cellulose binding domain PADR1 PF08063.12 KDO22221.1 - 0.19 11.5 0.2 0.19 11.5 0.2 3.4 3 0 0 3 3 3 0 PADR1 (NUC008) domain UCR_hinge PF02320.16 KDO22221.1 - 4.7 7.5 6.6 15 5.9 1.5 3.5 3 1 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein CBM_1 PF00734.18 KDO22222.1 - 4.6e-17 61.7 28.5 1.5e-09 37.6 13.1 4.5 7 0 0 7 7 7 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO22222.1 - 0.1 12.9 12.6 0.12 12.6 0.7 3.5 4 0 0 4 4 4 0 Toxin 7 CBM_1 PF00734.18 KDO22223.1 - 2.5e-13 49.7 23.1 4.9e-10 39.2 13.3 4.4 6 0 0 6 6 6 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO22223.1 - 0.0083 16.3 10.8 0.21 11.8 0.3 3.3 4 0 0 4 4 4 2 Toxin 7 VP4_2 PF08935.10 KDO22223.1 - 0.017 15.7 0.5 0.032 14.8 0.5 1.5 1 0 0 1 1 1 0 Viral protein VP4 subunit CBM_1 PF00734.18 KDO22224.1 - 7.3e-17 61.0 30.8 4e-10 39.5 12.9 3.5 4 0 0 4 4 4 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO22224.1 - 0.64 10.3 11.3 0.94 9.8 0.7 3.2 3 0 0 3 3 3 0 Toxin 7 VP4_2 PF08935.10 KDO22224.1 - 1.6 9.3 4.8 0.78 10.4 1.2 2.0 1 1 1 2 2 2 0 Viral protein VP4 subunit CBM_1 PF00734.18 KDO22225.1 - 4.5e-18 64.9 22.1 4.4e-10 39.3 6.2 4.3 6 0 0 6 6 6 2 Fungal cellulose binding domain CBM_1 PF00734.18 KDO22226.1 - 2.5e-17 62.5 22.6 7.9e-10 38.5 5.8 3.7 4 0 0 4 4 4 2 Fungal cellulose binding domain DUF842 PF05811.13 KDO22226.1 - 0.036 13.8 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) ADK PF00406.22 KDO22227.1 - 7.4e-45 152.7 0.0 8.9e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KDO22227.1 - 1.9e-24 86.6 0.0 3.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO22227.1 - 2e-07 31.6 0.0 3.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO22227.1 - 0.0014 18.8 0.0 0.0048 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KDO22227.1 - 0.0054 16.7 0.2 0.036 14.0 0.0 2.4 2 1 0 2 2 2 1 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 KDO22227.1 - 0.0074 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Limkain-b1 PF11608.8 KDO22227.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Hydin_ADK PF17213.3 KDO22227.1 - 0.032 14.5 0.2 10 6.4 0.0 2.2 1 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 KDO22227.1 - 0.067 12.9 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Ephrin_rec_like PF07699.13 KDO22229.1 - 1.5e-06 27.8 292.1 0.0069 16.1 9.9 30.4 9 6 24 33 33 33 22 Putative ephrin-receptor like NCD3G PF07562.14 KDO22229.1 - 3.7e-05 23.6 221.9 0.014 15.3 5.7 28.7 11 8 20 33 33 33 16 Nine Cysteines Domain of family 3 GPCR Form-deh_trans PF09163.11 KDO22229.1 - 3.8 7.4 4.8 0.63 9.9 0.3 2.1 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Ribonuclease_T2 PF00445.18 KDO22231.1 - 4e-21 76.1 0.1 5.4e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family AAA_12 PF13087.6 KDO22232.1 - 4.2e-41 140.8 0.0 5.4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KDO22232.1 - 2.6e-27 96.3 0.2 1.2e-13 51.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KDO22232.1 - 1.4e-12 47.7 0.0 5.2e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO22232.1 - 1.3e-10 41.8 0.0 9.3e-10 39.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 KDO22232.1 - 2.2e-05 24.0 0.0 0.078 12.3 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain ResIII PF04851.15 KDO22232.1 - 2.2e-05 24.5 0.0 5.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KDO22232.1 - 2.4e-05 24.2 0.1 0.19 11.4 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KDO22232.1 - 5.3e-05 23.0 0.1 0.00015 21.6 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KDO22232.1 - 5.5e-05 22.8 0.0 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KDO22232.1 - 0.0074 15.6 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KDO22232.1 - 0.0076 16.5 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KDO22232.1 - 0.015 14.3 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KDO22232.1 - 0.019 15.4 0.1 0.056 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain PIF1 PF05970.14 KDO22232.1 - 0.019 14.1 0.1 0.045 12.9 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Mg_chelatase PF01078.21 KDO22232.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KDO22232.1 - 0.09 12.2 0.0 0.97 8.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Helicase_RecD PF05127.14 KDO22232.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_7 PF12775.7 KDO22232.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KDO22232.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MRP-S34 PF16053.5 KDO22234.1 - 2.7e-18 65.9 0.1 3.3e-18 65.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 zf-CCCH_6 PF18585.1 KDO22235.1 - 0.26 11.2 1.8 4.8 7.2 0.2 3.8 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 U3_snoRNA_assoc PF08297.11 KDO22236.1 - 0.014 16.1 3.8 0.014 16.1 3.8 2.3 2 1 0 2 2 2 0 U3 snoRNA associated DUF4681 PF15732.5 KDO22236.1 - 0.029 14.6 1.1 0.074 13.3 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4681) Osteoregulin PF07175.11 KDO22236.1 - 0.041 14.1 4.5 0.054 13.7 4.5 1.2 1 0 0 1 1 1 0 Osteoregulin Chorion_2 PF03964.15 KDO22236.1 - 0.2 12.5 3.7 0.18 12.6 1.8 1.9 1 1 1 2 2 2 0 Chorion family 2 BSP_II PF05432.11 KDO22236.1 - 0.25 11.0 5.8 0.3 10.7 5.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PMSI1 PF15322.6 KDO22236.1 - 1.8 7.9 8.7 4.7 6.6 8.5 1.8 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative PBP1_TM PF14812.6 KDO22236.1 - 2.1 8.8 7.4 3.2 8.2 6.6 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPT6_acidic PF14632.6 KDO22236.1 - 7.9 7.1 10.9 19 5.9 3.4 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L32e PF01655.18 KDO22237.1 - 5.7e-50 168.3 1.5 7.2e-50 167.9 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Mannosyl_trans3 PF11051.8 KDO22238.1 - 2.1e-27 96.2 0.0 6.8e-26 91.2 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative MCM_bind PF09739.9 KDO22238.1 - 0.19 10.2 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Tyrosinase PF00264.20 KDO22239.1 - 3.4e-22 79.8 0.3 6.4e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 KDO22240.1 - 2.8e-21 76.8 0.4 6.8e-21 75.6 0.0 1.8 2 1 0 2 2 2 1 Common central domain of tyrosinase DAP3 PF10236.9 KDO22240.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FUN14 PF04930.15 KDO22241.1 - 0.00036 20.9 1.0 0.0026 18.1 1.0 2.3 1 1 0 1 1 1 1 FUN14 family MMPL PF03176.15 KDO22241.1 - 0.054 12.4 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 MMPL family Tyrosinase PF00264.20 KDO22242.1 - 2e-23 83.8 0.4 1.3e-22 81.2 0.1 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Ldh_1_N PF00056.23 KDO22243.1 - 7.3e-33 113.6 0.6 1.2e-32 113.0 0.6 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Lipase_3 PF01764.25 KDO22243.1 - 9e-21 74.2 0.1 4.1e-20 72.1 0.1 2.1 1 1 0 1 1 1 1 Lipase (class 3) 3Beta_HSD PF01073.19 KDO22243.1 - 1.2e-06 27.8 0.1 1.9e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 KDO22243.1 - 0.0044 17.7 0.0 0.014 16.0 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family THF_DHG_CYH_C PF02882.19 KDO22243.1 - 0.0061 15.9 0.3 0.018 14.3 0.3 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KDO22243.1 - 0.0073 16.2 0.2 0.012 15.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KDO22243.1 - 0.018 15.1 1.2 0.029 14.5 0.3 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF2974 PF11187.8 KDO22243.1 - 0.13 11.8 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Semialdhyde_dh PF01118.24 KDO22243.1 - 0.14 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 KDO22244.1 - 2.4e-40 138.7 0.3 4.4e-40 137.8 0.3 1.5 1 0 0 1 1 1 1 Subtilase family Cohesin_HEAT PF12765.7 KDO22244.1 - 0.091 13.1 0.6 0.21 11.9 0.6 1.6 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion TMEM135_C_rich PF15982.5 KDO22245.1 - 1e-08 35.8 1.0 1e-08 35.8 1.0 2.3 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KDO22245.1 - 1.7e-07 31.6 2.6 0.0044 17.4 0.1 3.0 3 1 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Rad51 PF08423.11 KDO22247.1 - 1.2e-122 408.1 0.1 1.4e-122 407.9 0.1 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KDO22247.1 - 1.3e-11 44.5 0.1 1.7e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KDO22247.1 - 2.4e-10 40.3 0.1 3.6e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KDO22247.1 - 8.3e-08 31.9 0.1 1.5e-07 31.0 0.1 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KDO22247.1 - 2.3e-05 23.9 0.1 0.00047 19.6 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KDO22247.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KDO22247.1 - 0.021 15.1 0.8 0.037 14.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain PAXNEB PF05625.11 KDO22247.1 - 0.17 11.0 0.1 3 6.9 0.1 2.1 2 0 0 2 2 2 0 PAXNEB protein HHH_5 PF14520.6 KDO22247.1 - 0.2 12.3 1.5 0.56 10.8 1.3 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix domain RecA PF00154.21 KDO22248.1 - 4.8e-137 455.7 2.7 5.9e-137 455.4 2.7 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 KDO22248.1 - 1.2e-12 47.6 0.8 2.5e-11 43.3 0.8 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KDO22248.1 - 6.9e-09 35.4 0.5 6.4e-07 28.9 0.0 2.7 1 1 1 2 2 2 1 KaiC ATPase_2 PF01637.18 KDO22248.1 - 3.8e-05 23.7 0.0 8.7e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KDO22248.1 - 6e-05 22.9 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO22248.1 - 0.00062 19.4 0.5 0.0096 15.5 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KDO22248.1 - 0.004 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO22248.1 - 0.0043 17.5 0.1 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CobU PF02283.16 KDO22248.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TK PF00265.18 KDO22248.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase DnaB_C PF03796.15 KDO22248.1 - 0.039 13.3 0.2 0.46 9.8 0.0 2.1 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KDO22248.1 - 0.05 13.6 0.0 0.76 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_35 PF14516.6 KDO22248.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain GRAM PF02893.20 KDO22249.1 - 0.0087 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.6 KDO22249.1 - 0.017 15.5 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.8 KDO22249.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 HEAT_EZ PF13513.6 KDO22250.1 - 0.0043 17.5 0.8 0.99 10.0 0.3 3.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT_EZ PF13513.6 KDO22251.1 - 0.17 12.4 1.7 5.1 7.7 0.1 2.6 2 0 0 2 2 2 0 HEAT-like repeat Calx-beta PF03160.14 KDO22252.1 - 5.1e-14 52.2 0.0 0.0085 16.2 0.1 4.2 4 0 0 4 4 4 3 Calx-beta domain TNFR_c6 PF00020.18 KDO22252.1 - 2.4e-11 43.8 43.2 8.4e-06 26.1 12.0 4.8 1 1 3 4 4 4 4 TNFR/NGFR cysteine-rich region Ank_2 PF12796.7 KDO22254.1 - 9.3e-06 26.1 0.0 2.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ion_trans PF00520.31 KDO22254.1 - 1.7e-05 24.2 13.3 1.7e-05 24.2 13.3 2.5 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO22254.1 - 4.8e-05 22.2 4.8 4.8e-05 22.2 4.8 2.0 2 0 0 2 2 2 1 Polycystin cation channel Ank_3 PF13606.6 KDO22254.1 - 0.00025 21.2 0.8 0.017 15.6 0.1 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KDO22254.1 - 0.00029 21.3 0.3 0.0019 18.7 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22254.1 - 0.035 14.4 0.3 0.26 11.6 0.2 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KDO22254.1 - 0.15 12.6 0.3 0.15 12.6 0.3 3.3 3 0 0 3 3 3 0 Ankyrin repeat UPF0182 PF03699.13 KDO22254.1 - 1.6 6.8 5.6 3 5.8 5.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) PKD_channel PF08016.12 KDO22255.1 - 1.4e-07 30.6 3.3 1.4e-07 30.6 3.3 2.4 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KDO22255.1 - 1.9e-07 30.6 17.9 1.9e-07 30.6 17.9 2.0 2 0 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 KDO22255.1 - 4.2e-06 27.3 0.1 1e-05 26.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22255.1 - 0.00014 22.4 1.2 0.028 15.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22255.1 - 0.00029 21.0 0.2 0.022 15.2 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KDO22255.1 - 0.00046 20.4 0.1 0.13 12.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) bZIP_1 PF00170.21 KDO22255.1 - 0.053 13.6 0.8 0.087 12.9 0.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF4407 PF14362.6 KDO22255.1 - 0.52 9.6 2.6 0.53 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ion_trans PF00520.31 KDO22256.1 - 7.4e-06 25.4 14.6 7.4e-06 25.4 14.6 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO22256.1 - 0.0055 15.4 3.0 0.0055 15.4 3.0 2.1 2 1 0 2 2 2 1 Polycystin cation channel UCH PF00443.29 KDO22257.1 - 0.008 15.7 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO22257.1 - 0.022 14.4 0.0 0.24 11.0 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Phage_holin_Dp1 PF16938.5 KDO22257.1 - 0.19 12.0 0.0 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative phage holin Dp-1 LRR_6 PF13516.6 KDO22258.1 - 3.2e-05 23.6 0.1 0.19 11.9 0.2 2.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KDO22258.1 - 0.0092 16.4 0.1 0.024 15.1 0.0 1.7 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KDO22259.1 - 3.9e-12 46.6 3.2 1.2e-06 29.1 0.2 3.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22259.1 - 1.5e-07 31.8 1.2 0.0018 18.8 0.0 4.2 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22259.1 - 0.00013 22.2 4.6 0.47 10.9 0.2 4.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22259.1 - 0.00025 21.2 3.5 25 5.9 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 KDO22259.1 - 0.029 14.8 1.8 1.5 9.4 0.1 4.0 3 1 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KDO22260.1 - 0.0087 16.6 0.0 0.032 14.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ion_trans PF00520.31 KDO22260.1 - 0.032 13.5 21.7 0.01 15.1 12.9 2.6 1 1 1 3 3 3 0 Ion transport protein Ank_5 PF13857.6 KDO22260.1 - 0.052 13.9 0.0 0.23 11.8 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22261.1 - 8.5e-06 26.3 0.2 2.1e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22261.1 - 0.00044 20.8 0.8 0.0053 17.3 0.3 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22261.1 - 0.0043 17.3 0.1 0.016 15.5 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22261.1 - 0.046 14.3 0.0 0.4 11.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat SBF_like PF13593.6 KDO22261.1 - 0.14 11.4 6.3 0.67 9.2 0.1 2.8 3 0 0 3 3 3 0 SBF-like CPA transporter family (DUF4137) Cytochrom_B_C PF00032.17 KDO22261.1 - 9.3 6.6 11.6 0.56 10.5 1.7 3.7 3 1 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD PX PF00787.24 KDO22263.1 - 4.8e-18 65.2 0.3 5.4e-18 65.0 0.3 1.0 1 0 0 1 1 1 1 PX domain Prominin PF05478.11 KDO22264.1 - 1.9e-07 29.5 5.5 1.1e-05 23.6 0.0 2.7 3 0 0 3 3 3 2 Prominin DUF2316 PF10078.9 KDO22264.1 - 0.2 11.9 1.7 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Baculo_PEP_C PF04513.12 KDO22264.1 - 2.9 8.0 15.2 1.8 8.6 1.2 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PX PF00787.24 KDO22266.1 - 0.00016 21.6 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 PX domain MFS_1 PF07690.16 KDO22267.1 - 5.2e-15 55.2 20.2 5.2e-15 55.2 20.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KDO22268.1 - 3.5e-12 45.9 25.3 3.5e-12 45.9 25.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily AAA PF00004.29 KDO22269.1 - 4.4e-06 27.1 0.0 8.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KDO22269.1 - 6.4e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO22269.1 - 5.4e-05 23.6 0.1 0.00017 22.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain FHA PF00498.26 KDO22269.1 - 0.00036 20.8 0.0 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 FHA domain CHAT PF12770.7 KDO22269.1 - 0.00099 18.6 0.5 0.0017 17.9 0.5 1.5 1 0 0 1 1 1 1 CHAT domain IstB_IS21 PF01695.17 KDO22269.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO22269.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO22269.1 - 0.007 16.9 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO22269.1 - 0.031 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KDO22269.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KDO22269.1 - 0.083 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Bac_DnaA PF00308.18 KDO22269.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein zf-C2H2 PF00096.26 KDO22271.1 - 7.9e-16 57.5 28.3 1.9e-05 24.9 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO22271.1 - 3.5e-12 46.1 26.2 0.0008 20.0 1.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO22271.1 - 3.5e-10 39.8 26.0 0.0019 18.5 0.9 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KDO22271.1 - 0.0056 17.0 13.0 0.19 12.0 7.9 2.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KDO22271.1 - 0.017 15.4 3.5 0.017 15.4 3.5 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 KDO22271.1 - 0.34 11.0 11.1 1.4 9.1 0.0 4.4 4 0 0 4 4 4 0 Zic proteins zinc finger domain FOXP-CC PF16159.5 KDO22271.1 - 0.49 11.1 12.5 0.83 10.3 0.7 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KDO22271.1 - 0.61 9.9 17.3 1.2 8.9 4.6 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type GAGA PF09237.11 KDO22271.1 - 0.92 9.4 4.3 0.81 9.5 0.5 2.4 2 0 0 2 2 2 0 GAGA factor zf-C2H2_aberr PF17017.5 KDO22271.1 - 1.7 8.7 7.2 1.1 9.4 0.1 2.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KDO22271.1 - 3.1 7.7 14.2 5.4 6.9 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KDO22271.1 - 3.1 7.7 5.7 0.43 10.5 0.4 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 KDO22272.1 - 1.6e-19 69.2 28.7 1.8e-05 24.9 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO22272.1 - 1.7e-12 47.2 24.0 0.00061 20.1 1.2 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO22272.1 - 1.4e-11 44.2 26.4 0.0081 16.9 0.6 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KDO22272.1 - 0.0033 17.7 12.9 0.13 12.5 4.1 2.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KDO22272.1 - 0.016 15.5 2.7 0.016 15.5 2.7 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF4764 PF15961.5 KDO22272.1 - 0.058 12.1 1.4 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) TnsD PF15978.5 KDO22272.1 - 0.096 11.7 0.6 0.12 11.3 0.6 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D zf_ZIC PF18366.1 KDO22272.1 - 0.12 12.6 9.1 1.5 9.0 0.1 4.0 4 0 0 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 KDO22272.1 - 0.25 11.1 13.6 0.87 9.4 1.5 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KDO22272.1 - 0.37 11.5 14.5 0.88 10.2 0.7 3.9 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KDO22272.1 - 4 7.9 18.5 2.1 8.7 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KDO22272.1 - 8.9 6.4 10.3 0.99 9.5 0.3 3.0 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KDO22273.1 - 1.2e-13 50.7 12.1 6.9e-06 26.2 0.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO22273.1 - 6.3e-12 45.3 10.2 0.0002 21.9 0.2 3.4 2 1 1 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO22273.1 - 1.4e-10 41.0 12.1 1.4e-07 31.6 0.6 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 KDO22273.1 - 1.2e-06 28.7 2.8 0.0018 18.6 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KDO22273.1 - 5.5e-05 23.3 8.2 0.02 15.2 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF4764 PF15961.5 KDO22273.1 - 0.00059 18.7 0.1 0.00069 18.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) zf-C2H2_6 PF13912.6 KDO22273.1 - 0.00081 19.3 0.3 0.00081 19.3 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KDO22273.1 - 0.026 14.9 2.4 0.075 13.4 1.8 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RRN7 PF11781.8 KDO22273.1 - 0.043 13.5 1.0 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_8 PF15909.5 KDO22273.1 - 0.096 13.0 2.1 2.1 8.7 2.1 2.2 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KDO22273.1 - 0.1 12.7 0.6 0.14 12.3 0.1 1.4 2 0 0 2 2 2 0 Aberrant zinc-finger zf-Di19 PF05605.12 KDO22273.1 - 0.37 11.1 4.5 1.3 9.4 0.8 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KDO22273.1 - 1.6 8.6 8.5 16 5.3 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Pyrid_oxidase_2 PF13883.6 KDO22275.1 - 5.1e-43 147.0 0.0 6.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KDO22275.1 - 3.2e-08 33.6 0.0 6.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EamA PF00892.20 KDO22275.1 - 0.029 14.5 0.6 2.7 8.1 0.4 2.5 2 0 0 2 2 2 0 EamA-like transporter family Ank_4 PF13637.6 KDO22277.1 - 0.035 14.7 2.0 0.14 12.8 0.2 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22278.1 - 1.2e-12 48.3 2.7 0.0047 17.5 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22278.1 - 4.5e-06 27.1 4.3 0.046 14.3 0.1 5.3 3 2 4 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22278.1 - 5e-06 26.7 11.8 0.091 13.1 0.1 6.3 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22278.1 - 6.4e-05 23.0 5.7 4.9 8.0 0.0 6.2 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 KDO22278.1 - 0.001 19.4 0.7 5.3 7.7 0.0 4.7 3 1 1 4 4 4 1 Ankyrin repeat HTH_1 PF00126.27 KDO22278.1 - 0.047 13.7 0.4 0.13 12.2 0.4 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Pkinase PF00069.25 KDO22279.1 - 1.1e-70 238.0 0.0 1.4e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22279.1 - 8.5e-34 117.0 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KDO22279.1 - 1.1e-07 31.8 0.1 2.3e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 PX domain Pkinase_C PF00433.24 KDO22279.1 - 2e-07 31.6 2.6 1.3e-05 25.8 1.1 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KDO22279.1 - 0.0049 16.2 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KDO22279.1 - 0.057 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-C2H2 PF00096.26 KDO22280.1 - 1.2e-10 41.2 25.1 0.00026 21.3 1.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO22280.1 - 1.2e-09 38.1 17.4 3.2e-05 24.1 1.4 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO22280.1 - 1.3e-07 31.9 22.1 0.014 16.2 3.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KDO22280.1 - 0.00021 21.0 1.1 0.00021 21.0 1.1 2.8 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KDO22280.1 - 0.0084 16.4 7.7 0.03 14.6 7.0 2.0 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KDO22280.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.2 2 1 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KDO22280.1 - 0.37 11.5 5.6 2.6 8.8 0.1 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KDO22280.1 - 0.63 10.8 9.2 0.15 12.7 3.1 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2HE PF16278.5 KDO22280.1 - 6.6 7.3 9.7 8.1 7.0 0.2 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PP2C PF00481.21 KDO22281.1 - 6.2e-33 114.5 0.0 9.4e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO22281.1 - 0.0068 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Prominin PF05478.11 KDO22282.1 - 0.00029 19.0 0.2 0.00029 19.0 0.2 3.3 3 1 0 3 3 3 2 Prominin Na_Pi_cotrans PF02690.15 KDO22283.1 - 4.6e-33 114.3 21.5 5e-20 72.0 6.0 3.0 3 1 0 3 3 3 2 Na+/Pi-cotransporter RhodobacterPufX PF11511.8 KDO22283.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.2 4 0 0 4 4 4 0 Intrinsic membrane protein PufX IL12 PF03039.14 KDO22284.1 - 0.13 11.5 0.2 0.15 11.4 0.2 1.0 1 0 0 1 1 1 0 Interleukin-12 alpha subunit IBR PF01485.21 KDO22285.1 - 0.00085 19.5 15.5 0.00085 19.5 15.5 4.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain Ank_4 PF13637.6 KDO22286.1 - 5.7e-08 33.2 0.5 1.5e-05 25.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22286.1 - 0.00013 22.5 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO22286.1 - 0.0032 17.7 0.1 0.43 11.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22286.1 - 0.0077 16.7 0.0 1.3 9.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat TetR_C_6 PF13977.6 KDO22286.1 - 0.031 14.5 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Ank_5 PF13857.6 KDO22287.1 - 0.00059 20.1 0.2 0.61 10.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO22287.1 - 0.0048 17.4 0.3 0.018 15.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22287.1 - 0.021 15.4 0.1 0.05 14.2 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22287.1 - 0.19 12.4 0.5 2.9 8.7 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat zf-RING_2 PF13639.6 KDO22289.1 - 1.9e-09 37.7 13.4 1.9e-09 37.7 13.4 2.1 2 0 0 2 2 1 1 Ring finger domain PX PF00787.24 KDO22289.1 - 2.2e-08 34.0 0.2 4.9e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 KDO22289.1 - 7e-08 32.6 12.0 7e-08 32.6 12.0 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO22289.1 - 4.8e-06 26.4 12.9 1.3e-05 24.9 12.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22289.1 - 0.00044 20.2 9.0 0.00044 20.2 9.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO22289.1 - 0.00087 19.0 10.0 0.00087 19.0 10.0 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KDO22289.1 - 0.00092 19.2 8.5 0.00092 19.2 8.5 2.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO22289.1 - 0.0016 18.3 10.7 0.0016 18.3 10.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO22289.1 - 0.0021 17.9 11.7 0.006 16.4 10.5 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO22289.1 - 0.0063 16.3 14.7 0.0063 16.3 14.7 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) CDT1 PF08839.11 KDO22289.1 - 0.075 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 DNA replication factor CDT1 like FANCL_C PF11793.8 KDO22289.1 - 0.33 11.1 11.4 1.4 9.2 11.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KDO22289.1 - 0.49 10.3 11.8 2.5 8.0 11.2 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KDO22289.1 - 1.6 8.8 9.3 1 9.4 6.3 2.3 2 0 0 2 2 2 0 Zinc-finger RINGv PF12906.7 KDO22289.1 - 2.5 8.3 12.0 6.1 7.0 12.0 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KDO22289.1 - 2.9 7.6 12.4 6.7 6.4 12.4 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO22289.1 - 5.1 7.0 9.2 8.2 6.3 3.1 3.1 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit LTV PF04180.14 KDO22292.1 - 1e-28 101.2 23.9 3.1e-22 79.9 23.9 2.6 1 1 0 1 1 1 1 Low temperature viability protein EFhand_Ca_insen PF08726.10 KDO22292.1 - 0.0041 17.2 0.5 0.068 13.3 0.3 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand LYRIC PF15686.5 KDO22292.1 - 0.27 10.7 8.4 0.4 10.2 8.4 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family zf-RING_2 PF13639.6 KDO22293.1 - 4.5e-12 46.1 6.1 4.5e-12 46.1 6.1 2.1 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 KDO22293.1 - 8.8e-10 38.6 2.0 1.1e-09 38.3 1.2 1.6 1 1 1 2 2 2 1 PX domain zf-rbx1 PF12678.7 KDO22293.1 - 2.6e-09 37.2 8.0 1.3e-08 34.9 8.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO22293.1 - 4.2e-08 32.9 6.5 1.2e-07 31.5 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO22293.1 - 4.7e-07 29.6 1.5 1e-06 28.5 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO22293.1 - 2.6e-06 27.1 3.8 8.9e-06 25.3 3.8 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO22293.1 - 3.1e-06 26.9 5.3 3.1e-06 26.9 5.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22293.1 - 5.6e-06 26.3 3.2 9.2e-06 25.6 2.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KDO22293.1 - 0.00019 21.0 3.6 0.00061 19.4 3.6 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KDO22293.1 - 0.00021 21.2 5.7 0.00062 19.7 5.2 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO22293.1 - 0.00039 20.2 5.8 0.0013 18.5 5.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO22293.1 - 0.00093 19.2 4.5 0.0023 17.9 4.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KDO22293.1 - 0.027 14.6 3.9 0.12 12.5 3.9 2.2 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KDO22293.1 - 0.029 14.5 6.8 0.093 12.9 6.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 KDO22293.1 - 0.25 11.5 4.1 0.12 12.6 1.5 1.9 2 0 0 2 2 1 0 Zinc-ribbon like family zf-Nse PF11789.8 KDO22293.1 - 0.4 10.5 3.1 0.99 9.3 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 KDO22293.1 - 1.4 9.0 6.1 3.6 7.7 6.1 1.8 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KDO22293.1 - 1.8 8.8 8.9 0.49 10.6 4.2 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain Acetyltransf_1 PF00583.25 KDO22294.1 - 0.00019 21.6 0.0 0.00079 19.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KDO22294.1 - 0.00024 21.2 0.1 0.00082 19.5 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO22294.1 - 0.00073 19.9 0.0 0.002 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO22294.1 - 0.089 13.5 0.0 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO22294.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNF2_N PF00176.23 KDO22295.1 - 3.9e-35 121.2 0.0 3.8e-33 114.7 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 KDO22295.1 - 5.2e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO22295.1 - 0.00087 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KDO22295.1 - 0.015 15.2 9.4 0.029 14.2 9.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO22295.1 - 0.034 14.1 8.8 0.082 12.9 8.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain AAA_19 PF13245.6 KDO22295.1 - 0.074 13.4 0.0 0.35 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 KDO22295.1 - 0.23 11.8 7.5 0.67 10.3 7.5 1.8 1 0 0 1 1 1 0 Ring finger domain TPR_12 PF13424.6 KDO22296.1 - 1.6e-17 63.5 4.5 3.4e-07 30.5 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22296.1 - 5.5e-16 57.9 1.5 6.2e-07 29.1 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO22296.1 - 0.00053 19.5 1.3 0.015 14.6 1.0 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KDO22296.1 - 0.0025 18.3 0.6 12 6.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22296.1 - 0.059 13.5 2.5 1.4 9.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_7 PF13508.7 KDO22297.1 - 0.088 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO22298.1 - 0.00017 22.0 0.0 0.00035 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO22298.1 - 0.0087 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO22298.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF4209 PF13910.6 KDO22305.1 - 6.9e-19 67.9 0.0 1.4e-15 57.3 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Vps62 PF06101.11 KDO22306.1 - 0.0019 16.6 0.1 0.089 11.1 0.0 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 62 Syntaxin_2 PF14523.6 KDO22306.1 - 1.2 9.6 4.2 1.8 9.0 0.4 2.6 1 1 1 2 2 2 0 Syntaxin-like protein DIM PF08194.12 KDO22307.1 - 0.0029 17.8 0.7 0.0079 16.4 0.7 1.8 1 0 0 1 1 1 1 DIM protein Vps62 PF06101.11 KDO22307.1 - 0.03 12.6 0.3 0.43 8.8 0.1 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 62 Pkinase_Tyr PF07714.17 KDO22308.1 - 1.4e-39 136.0 0.0 1.7e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22308.1 - 3.4e-29 102.0 0.0 5.3e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KDO22309.1 - 2.8e-68 226.5 6.7 1.6e-13 51.0 0.0 8.0 1 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO22309.1 - 1.3e-53 178.4 26.8 1.3e-08 34.9 0.1 13.7 3 2 11 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22309.1 - 5.5e-52 167.7 20.1 0.006 17.0 0.0 14.9 15 1 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.6 KDO22309.1 - 4.2e-51 170.7 11.0 1.5e-07 31.9 0.0 11.5 4 3 9 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 KDO22309.1 - 1.1e-34 117.3 39.3 0.003 17.9 0.0 14.1 15 0 0 15 15 15 11 Ankyrin repeat Invas_SpaK PF03519.14 KDO22309.1 - 0.00096 19.2 1.2 0.3 11.2 0.1 3.6 3 1 1 4 4 4 1 Invasion protein B family LicD PF04991.13 KDO22310.1 - 0.013 15.6 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 LicD family LicD PF04991.13 KDO22311.1 - 0.0033 17.6 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 LicD family LicD PF04991.13 KDO22312.1 - 0.0019 18.4 0.1 0.0036 17.5 0.1 1.5 1 0 0 1 1 1 1 LicD family DoxX_2 PF13564.6 KDO22313.1 - 0.058 13.5 0.4 0.08 13.1 0.4 1.2 1 0 0 1 1 1 0 DoxX-like family Glyco_hydro_38N PF01074.22 KDO22316.1 - 1.9e-82 276.9 4.3 2.7e-82 276.4 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KDO22316.1 - 1.9e-29 103.2 0.0 3.8e-29 102.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KDO22316.1 - 5.7e-21 74.5 0.4 1.1e-20 73.5 0.4 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KDO22316.1 - 0.082 13.0 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_transf_8 PF01501.20 KDO22317.1 - 5.6e-08 32.7 2.6 3.7e-05 23.4 0.3 2.2 1 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KDO22317.1 - 2.3e-05 23.9 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Acyl_transf_3 PF01757.22 KDO22318.1 - 1.8e-20 73.3 27.2 1.1e-14 54.3 16.3 2.5 2 1 1 3 3 3 2 Acyltransferase family CD20 PF04103.15 KDO22318.1 - 0.6 10.2 5.7 0.14 12.2 0.5 2.5 2 1 0 2 2 2 0 CD20-like family DUF2403 PF10290.9 KDO22319.1 - 0.2 12.1 5.9 1.5 9.3 0.1 3.4 3 0 0 3 3 3 0 Glycine-rich protein domain (DUF2403) Elicitin PF00964.17 KDO22320.1 - 0.00018 21.6 2.9 0.00084 19.4 0.5 2.6 2 1 0 2 2 2 1 Elicitin Choline_transpo PF04515.12 KDO22321.1 - 1.6e-26 93.3 36.2 3.8e-21 75.6 11.7 3.7 2 2 1 3 3 3 2 Plasma-membrane choline transporter Elicitin PF00964.17 KDO22322.1 - 2.4e-05 24.3 0.8 2.4e-05 24.3 0.8 4.3 3 2 0 3 3 3 1 Elicitin CBM_21 PF03370.13 KDO22322.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) Tub PF01167.18 KDO22324.1 - 3.2e-29 102.4 0.0 4.6e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Tub family Ank_2 PF12796.7 KDO22325.1 - 7.7e-87 286.0 23.3 4.2e-12 46.5 0.2 12.6 3 2 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22325.1 - 9.8e-63 200.7 43.4 0.0018 18.6 0.0 24.3 25 0 0 25 25 25 15 Ankyrin repeat Ank_4 PF13637.6 KDO22325.1 - 2.7e-62 206.4 43.9 5.6e-07 30.0 0.1 17.2 9 4 9 18 18 18 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22325.1 - 9.5e-52 172.4 59.3 9.3e-08 32.2 0.2 17.7 9 6 11 20 20 20 17 Ankyrin repeats (many copies) Ank PF00023.30 KDO22325.1 - 1.1e-36 123.7 73.4 0.0027 18.1 0.1 20.5 19 2 0 19 19 19 13 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO22326.1 - 9.2e-66 221.8 0.0 5e-33 114.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO22326.1 - 6.7e-56 189.6 0.0 6.8e-27 94.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KDO22326.1 - 2.3e-05 23.9 0.1 0.00094 18.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO22326.1 - 3.8e-05 23.7 0.3 0.00016 21.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO22326.1 - 0.012 15.0 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like DUF3392 PF11872.8 KDO22326.1 - 0.13 12.5 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) DUF4419 PF14388.6 KDO22327.1 - 7.6e-79 265.3 0.0 5.1e-78 262.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) UCH PF00443.29 KDO22328.1 - 1.9e-45 155.4 0.0 2.8e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO22328.1 - 1.4e-23 84.0 0.4 1.2e-21 77.7 0.4 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Condensin2nSMC PF12422.8 KDO22329.1 - 4.8e-40 137.2 0.6 2.1e-39 135.1 0.1 2.4 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KDO22329.1 - 1.5e-05 24.9 4.2 0.16 12.3 0.1 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KDO22329.1 - 0.018 15.4 8.5 0.94 9.9 0.1 5.7 6 1 1 7 7 7 0 HEAT repeats CPDase PF07823.11 KDO22329.1 - 0.022 14.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Adaptin_N PF01602.20 KDO22329.1 - 0.087 11.4 1.5 0.14 10.7 0.2 1.9 2 0 0 2 2 2 0 Adaptin N terminal region TetR_C_11 PF16859.5 KDO22329.1 - 0.21 11.9 11.6 0.1 12.9 1.9 4.7 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain DUF2306 PF10067.9 KDO22332.1 - 9.2e-07 29.2 6.6 9.2e-07 29.2 6.6 2.3 2 1 1 3 3 3 1 Predicted membrane protein (DUF2306) Cytochrom_B561 PF03188.16 KDO22332.1 - 0.021 14.9 1.0 0.044 13.9 0.3 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF420 PF04238.12 KDO22332.1 - 0.03 14.6 1.2 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Nup96 PF12110.8 KDO22332.1 - 0.063 12.4 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Na_Pi_cotrans PF02690.15 KDO22333.1 - 3e-41 140.8 26.5 3.1e-23 82.4 8.0 2.8 2 1 0 2 2 2 2 Na+/Pi-cotransporter CYYR1 PF10873.8 KDO22333.1 - 2.1 8.8 5.5 0.41 11.1 0.6 2.3 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Cation_ATPase_C PF00689.21 KDO22334.1 - 3.2e-40 137.8 0.4 3.2e-40 137.8 0.4 1.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Ost5 PF05251.12 KDO22334.1 - 0.018 15.3 2.9 0.063 13.6 1.6 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF4870 PF09685.10 KDO22334.1 - 0.9 9.7 4.8 0.3 11.2 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Cation_ATPase_C PF00689.21 KDO22335.1 - 3.1e-39 134.5 2.5 5.9e-39 133.6 0.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO22335.1 - 1.3e-28 99.7 2.4 9.5e-20 70.9 0.1 3.3 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 KDO22335.1 - 1.3e-18 66.8 0.0 2.5e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO22335.1 - 9.1e-15 55.5 0.6 8.7e-14 52.3 0.6 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO22335.1 - 3.3e-09 36.3 0.0 6.5e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO22335.1 - 0.00096 19.0 1.0 0.011 15.5 0.5 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO22335.1 - 0.071 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 KDO22335.1 - 0.15 12.1 0.5 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term DUF1774 PF08611.10 KDO22335.1 - 0.25 11.7 2.8 3.5 8.0 0.2 2.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Ost5 PF05251.12 KDO22335.1 - 1.2 9.5 6.2 0.88 9.9 2.6 2.8 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Pkinase PF00069.25 KDO22336.1 - 1.3e-46 159.1 0.0 1.7e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22336.1 - 7.6e-24 84.4 0.0 9.7e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO22336.1 - 0.011 15.0 0.4 0.017 14.5 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO22336.1 - 0.09 12.1 0.9 0.49 9.7 0.9 1.9 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KDO22336.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SidE PF12252.8 KDO22336.1 - 0.32 8.5 0.1 0.42 8.1 0.1 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Pkinase PF00069.25 KDO22337.1 - 5.5e-52 176.7 0.0 2.1e-51 174.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22337.1 - 7.4e-24 84.4 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO22337.1 - 0.00021 20.3 0.0 0.00029 19.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO22337.1 - 0.00038 19.9 0.0 0.0012 18.3 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO22337.1 - 0.0011 18.3 0.4 0.0019 17.6 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO22337.1 - 0.0014 18.6 2.5 0.077 12.9 0.5 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO22337.1 - 0.019 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TetR_C_28 PF17937.1 KDO22337.1 - 0.037 14.5 2.7 0.72 10.3 0.2 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain p450 PF00067.22 KDO22339.1 - 8.7e-83 278.6 0.0 9.9e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.12 KDO22340.1 - 7e-18 65.1 0.0 1.7e-17 63.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO22340.1 - 1.7e-16 60.7 0.0 4e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO22340.1 - 6.4e-14 52.0 0.0 7.9e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO22340.1 - 1.4e-13 51.4 0.0 2.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO22340.1 - 1.9e-10 40.8 0.0 2.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KDO22340.1 - 8.4e-07 28.8 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KDO22340.1 - 8.8e-06 25.2 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KDO22340.1 - 0.00046 19.8 0.0 0.0009 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KDO22340.1 - 0.0035 17.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 KDO22340.1 - 0.0035 18.3 0.0 0.0081 17.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 KDO22340.1 - 0.0081 16.3 0.0 0.014 15.5 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 KDO22340.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 KDO22340.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.20 KDO22340.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KDO22340.1 - 0.039 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KDO22340.1 - 0.055 13.1 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) tRNA_U5-meth_tr PF05958.11 KDO22340.1 - 0.16 10.9 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Bin3 PF06859.12 KDO22340.1 - 0.16 12.6 0.0 0.44 11.2 0.0 1.6 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) PCMT PF01135.19 KDO22340.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NUDIX PF00293.28 KDO22341.1 - 8.7e-16 58.2 0.2 1.1e-15 57.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Ricin_B_lectin PF00652.22 KDO22342.1 - 3.8e-31 108.0 17.3 6.5e-16 58.7 4.7 3.5 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO22342.1 - 3.1e-15 56.7 18.5 2e-08 34.8 2.8 5.1 3 1 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO22342.1 - 1.8e-06 27.6 6.9 0.096 12.3 0.4 3.7 2 1 1 3 3 3 3 Cytolethal distending toxin A/C domain Glyco_hydro_17 PF00332.18 KDO22342.1 - 0.0013 18.5 1.3 0.0025 17.5 1.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 ET PF01684.16 KDO22342.1 - 1.1 9.6 3.3 25 5.3 0.1 2.8 2 1 0 2 2 2 0 ET module IgG_binding_B PF01378.17 KDO22342.1 - 3.9 7.6 8.4 6.4 6.9 0.3 3.1 2 1 1 3 3 3 0 B domain Ricin_B_lectin PF00652.22 KDO22343.1 - 2.8e-51 173.1 25.8 3.5e-15 56.4 0.1 3.0 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO22343.1 - 2.2e-17 63.5 9.8 4e-06 27.5 1.2 4.3 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_17 PF00332.18 KDO22343.1 - 0.00047 19.8 3.3 0.00093 18.9 2.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 CDtoxinA PF03498.14 KDO22343.1 - 0.00083 19.0 0.2 0.43 10.1 0.0 2.8 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain IgG_binding_B PF01378.17 KDO22343.1 - 0.2 11.7 3.9 3 8.0 0.9 2.9 2 1 0 2 2 2 0 B domain Ricin_B_lectin PF00652.22 KDO22344.1 - 1.1e-18 67.6 9.8 2.8e-14 53.5 5.4 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KDO22344.1 - 6.6e-07 29.0 2.2 0.0004 20.0 0.4 2.6 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain Glyco_hydro_17 PF00332.18 KDO22344.1 - 2.2e-05 24.2 3.8 0.00013 21.6 1.7 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 zf-RanBP PF00641.18 KDO22345.1 - 0.011 15.1 3.0 0.011 15.1 3.0 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HECT PF00632.25 KDO22346.1 - 7.7e-72 242.4 0.0 9.8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ricin_B_lectin PF00652.22 KDO22347.1 - 5.6e-28 97.7 11.8 1.9e-13 50.8 3.8 2.6 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO22347.1 - 9.7e-10 39.1 12.1 0.00036 21.2 0.6 3.7 1 1 3 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO22347.1 - 0.00026 20.6 1.8 0.15 11.7 0.0 2.6 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain Glyco_hydro_17 PF00332.18 KDO22347.1 - 0.044 13.4 1.5 0.13 11.9 0.3 2.4 3 1 1 4 4 4 0 Glycosyl hydrolases family 17 IgG_binding_B PF01378.17 KDO22347.1 - 0.077 13.1 9.1 0.85 9.7 1.6 2.9 2 1 0 2 2 2 0 B domain ET PF01684.16 KDO22347.1 - 1.6 9.1 3.7 0.8 10.1 0.2 2.2 3 0 0 3 3 3 0 ET module Peptidase_C1_2 PF03051.15 KDO22348.1 - 6.4e-139 463.5 0.0 7.2e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO22348.1 - 9.1e-06 25.9 1.6 0.0012 18.9 0.8 2.2 2 0 0 2 2 2 2 Papain family cysteine protease 2OG-FeII_Oxy_2 PF13532.6 KDO22352.1 - 1.8e-07 31.6 0.1 2.1e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KDO22353.1 - 5.4e-48 163.7 0.0 1.4e-47 162.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22353.1 - 2.2e-29 102.5 0.0 6.1e-29 101.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO22353.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO22353.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KDO22353.1 - 0.0031 17.5 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Homoserine_dh PF00742.19 KDO22354.1 - 2.6e-54 183.7 1.0 4.8e-54 182.9 1.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KDO22354.1 - 5.4e-15 56.1 0.2 1e-14 55.2 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Thiol_cytolysin PF01289.19 KDO22354.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin ACT PF01842.25 KDO22354.1 - 0.09 12.6 0.2 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 ACT domain Peptidase_C1 PF00112.23 KDO22355.1 - 0.00022 21.4 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease FluMu_N PF17891.1 KDO22356.1 - 0.015 15.1 0.3 0.056 13.2 0.3 2.0 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain MFS_1 PF07690.16 KDO22357.1 - 1.5e-30 106.4 27.5 2e-30 105.9 27.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KDO22357.1 - 9.2e-21 73.7 0.1 9.2e-21 73.7 0.1 2.7 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO22357.1 - 1.7e-13 50.2 13.6 1.7e-13 50.2 13.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Syja_N PF02383.18 KDO22358.1 - 1.7e-79 267.4 0.0 2.6e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Glyco_hydro_18 PF00704.28 KDO22361.1 - 3.3e-27 96.1 0.1 4.5e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5447 PF17525.2 KDO22361.1 - 0.0066 16.9 0.1 0.066 13.7 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5447) KAP PF05804.12 KDO22362.1 - 1.9e-128 429.6 22.7 8.5e-128 427.5 22.7 1.8 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 KDO22362.1 - 0.0028 17.7 5.0 2.8 8.1 0.0 5.4 6 1 1 7 7 7 2 Armadillo/beta-catenin-like repeat HSP33 PF01430.19 KDO22363.1 - 3.5e-34 118.4 0.0 4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein CRPV_capsid PF08762.10 KDO22363.1 - 0.061 13.0 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 CRPV capsid protein like HD PF01966.22 KDO22364.1 - 1.1e-05 25.6 0.7 3.7e-05 23.9 0.2 2.0 2 1 0 2 2 2 1 HD domain DUF4605 PF15378.6 KDO22365.1 - 0.00035 20.4 1.4 0.00054 19.8 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Cyclin_N PF00134.23 KDO22366.1 - 3.2e-09 36.6 0.0 1.5e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ank_4 PF13637.6 KDO22367.1 - 1.9e-10 41.1 1.9 4.5e-10 39.8 0.8 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22367.1 - 5e-10 39.8 0.3 8.8e-10 39.0 0.3 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO22367.1 - 1.9e-07 31.2 1.4 0.00063 20.0 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO22367.1 - 7.5e-07 29.3 2.8 0.00055 20.3 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO22367.1 - 8.3e-05 22.7 0.9 0.14 12.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.29 KDO22367.1 - 0.0047 17.4 0.0 0.0073 16.8 0.0 1.3 1 0 0 1 1 1 1 PH domain Myb_DNA-bind_4 PF13837.6 KDO22368.1 - 0.00079 19.8 1.0 0.0037 17.6 0.0 2.3 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain Halo_GVPC PF05465.13 KDO22368.1 - 0.07 13.4 2.8 0.26 11.6 0.4 2.7 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Sulfotransfer_3 PF13469.6 KDO22369.1 - 2.6e-37 129.3 0.0 5.6e-37 128.2 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KDO22369.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KDO22369.1 - 0.0055 16.6 0.1 1.2 8.9 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulphotransf PF09037.10 KDO22369.1 - 0.0055 16.3 0.1 1.2 8.6 0.0 2.3 2 1 0 2 2 2 2 Stf0 sulphotransferase Sulfotransfer_3 PF13469.6 KDO22370.1 - 4.3e-36 125.3 0.1 9.4e-36 124.2 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KDO22370.1 - 1.3e-09 38.0 0.1 2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KDO22370.1 - 0.005 16.7 0.6 0.22 11.3 0.2 2.4 2 1 0 2 2 2 1 Sulfotransferase domain Ank_5 PF13857.6 KDO22371.1 - 3.3e-17 62.3 1.2 8.8e-11 41.8 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KDO22371.1 - 2.5e-15 56.0 10.1 4.3e-15 55.3 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 KDO22371.1 - 1.2e-14 54.7 0.1 2.6e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO22371.1 - 6.3e-13 48.5 0.1 2.9e-06 27.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO22371.1 - 9.7e-13 47.1 0.6 9.6e-05 22.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KDO22371.1 - 3.1e-12 46.8 2.4 2.7e-09 37.4 0.1 2.7 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 KDO22371.1 - 5.6e-07 29.3 9.7 1e-06 28.5 9.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO22371.1 - 1.9e-06 28.1 10.9 1.9e-06 28.1 10.9 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO22371.1 - 0.00014 21.6 10.4 0.0003 20.5 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22371.1 - 0.0029 17.5 10.0 0.0064 16.4 10.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ABC_tran_CTD PF16326.5 KDO22371.1 - 0.18 12.1 7.1 8.1 6.8 0.1 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain zf-RING_4 PF14570.6 KDO22371.1 - 0.57 10.0 7.6 1.7 8.5 7.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KDO22371.1 - 1.6 8.4 9.3 0.078 12.6 3.5 1.8 2 0 0 2 2 2 0 P-11 zinc finger Rubredoxin_2 PF18073.1 KDO22371.1 - 3.4 7.5 6.0 0.77 9.5 1.9 2.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ax_dynein_light PF10211.9 KDO22371.1 - 4.2 7.3 8.8 12 5.8 8.1 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain zf-C3HC4_3 PF13920.6 KDO22372.1 - 2.4e-14 52.9 11.4 2.4e-14 52.9 11.4 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KDO22372.1 - 4.4e-14 52.4 0.0 1.3e-07 31.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO22372.1 - 4.7e-14 52.6 0.5 3.4e-11 43.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22372.1 - 1.8e-12 47.7 0.1 3.6e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO22372.1 - 4.3e-12 45.9 0.5 1.7e-06 28.2 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO22372.1 - 1e-09 37.8 0.1 0.0052 17.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 KDO22372.1 - 5.1e-06 26.7 12.3 5.1e-06 26.7 12.3 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KDO22372.1 - 1.3e-05 24.9 11.6 1.3e-05 24.9 11.6 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO22372.1 - 0.00026 20.8 12.0 0.0005 19.9 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO22372.1 - 0.0025 17.6 12.5 0.0025 17.6 12.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22372.1 - 0.0058 16.6 11.7 0.0058 16.6 11.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 KDO22372.1 - 0.18 11.6 9.8 0.37 10.6 9.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KDO22372.1 - 3.3 7.8 9.4 0.42 10.7 1.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 KDO22372.1 - 5.5 7.2 11.4 15 5.9 11.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CCDC85 PF10226.9 KDO22373.1 - 0.00094 18.9 0.4 0.0015 18.2 0.4 1.3 1 0 0 1 1 1 1 CCDC85 family DUF4772 PF15997.5 KDO22373.1 - 0.044 14.4 0.2 6.9 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4772) Abhydrolase_1 PF00561.20 KDO22374.1 - 4.2e-07 29.9 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO22374.1 - 0.00092 18.5 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF3724 PF12521.8 KDO22374.1 - 0.011 15.5 0.1 0.039 13.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) DUF2920 PF11144.8 KDO22374.1 - 0.062 12.5 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 KDO22374.1 - 0.14 12.7 0.1 0.49 11.0 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO22375.1 - 9.9e-06 25.4 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO22375.1 - 0.00076 18.8 0.0 0.015 14.6 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KDO22375.1 - 0.0078 15.4 0.0 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) HCV_NS4b PF01001.19 KDO22375.1 - 0.12 12.0 0.8 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b Exo_endo_phos PF03372.23 KDO22376.1 - 1.1e-19 70.9 0.0 1.7e-19 70.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KDO22376.1 - 0.017 15.0 0.0 0.36 10.7 0.0 2.7 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Acyl-CoA_dh_N PF02771.16 KDO22377.1 - 1.8e-29 102.7 0.0 3.6e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KDO22377.1 - 3.1e-27 95.6 0.0 5.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KDO22377.1 - 5.4e-22 77.8 0.0 8.6e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KDO22377.1 - 4.1e-05 23.9 0.1 0.00086 19.6 0.1 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FMO-like PF00743.19 KDO22379.1 - 9.6e-25 87.0 0.0 8e-22 77.3 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KDO22379.1 - 1.1e-12 47.8 0.0 7e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO22379.1 - 3.7e-11 42.8 0.0 8.6e-10 38.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KDO22379.1 - 2.8e-10 39.9 0.0 4.2e-05 22.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KDO22379.1 - 3.8e-10 39.9 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KDO22379.1 - 2e-06 27.8 1.2 0.0011 19.0 0.5 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KDO22379.1 - 2.1e-06 27.6 0.3 2.2e-05 24.2 0.1 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KDO22379.1 - 0.00085 18.7 0.1 0.59 9.3 0.1 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KDO22379.1 - 0.028 13.2 0.1 0.045 12.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KDO22379.1 - 0.078 13.5 0.0 0.61 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ExoD PF06055.12 KDO22379.1 - 0.26 10.6 3.9 0.38 10.1 2.7 1.8 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Glyco_hydro_3 PF00933.21 KDO22380.1 - 2.8e-55 187.9 0.0 3.7e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KDO22380.1 - 7.6e-36 124.0 0.0 1.7e-35 122.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KDO22380.1 - 1.9e-06 27.9 0.0 4.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Carn_acyltransf PF00755.20 KDO22381.1 - 8.1e-170 566.3 0.0 9.2e-170 566.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TrmE_N PF10396.9 KDO22381.1 - 0.11 12.8 0.1 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus WD40 PF00400.32 KDO22382.1 - 1.3e-12 48.0 4.8 0.00015 22.5 0.4 6.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO22382.1 - 0.00027 21.2 0.0 2.6 8.4 0.0 4.3 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ERM PF00769.19 KDO22382.1 - 0.0061 16.4 12.8 0.0061 16.4 12.8 3.5 2 1 0 3 3 3 1 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 KDO22382.1 - 6.7 4.5 14.3 14 3.5 14.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DAGAT PF03982.13 KDO22383.1 - 0.0084 15.1 0.1 0.0089 15.0 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FAM193_C PF15914.5 KDO22384.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 FAM193 family C-terminal DUF2322 PF10084.9 KDO22384.1 - 0.22 11.6 0.0 0.56 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Vps54 PF07928.12 KDO22385.1 - 1e-43 149.0 5.2 1.6e-43 148.4 2.6 2.7 2 0 0 2 2 2 1 Vps54-like protein Glyco_hydro_3_C PF01915.22 KDO22385.1 - 4.4e-20 72.5 0.0 1.1e-16 61.4 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Vps54_N PF10475.9 KDO22385.1 - 2.2e-18 66.6 11.6 1e-17 64.4 0.6 3.0 3 0 0 3 3 3 2 Vacuolar-sorting protein 54, of GARP complex Fn3-like PF14310.6 KDO22385.1 - 3.3e-05 23.9 0.0 8.8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain COG2 PF06148.11 KDO22385.1 - 0.0047 17.0 4.4 0.0047 17.0 4.4 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF334 PF03904.13 KDO22385.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sec8_exocyst PF04048.14 KDO22385.1 - 0.16 11.9 6.9 0.078 12.9 3.2 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain zf-A20 PF01754.16 KDO22387.1 - 3.5e-11 42.8 5.9 3.5e-11 42.8 5.9 2.1 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.16 KDO22387.1 - 7.7e-05 22.8 4.4 7.7e-05 22.8 4.4 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger Arm PF00514.23 KDO22388.1 - 7.6e-06 25.8 8.0 0.05 13.7 0.0 5.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KDO22388.1 - 0.00013 22.0 0.0 0.0063 16.5 0.0 2.6 1 1 1 2 2 2 1 Spinocerebellar ataxia type 10 protein domain BT1 PF03092.16 KDO22389.1 - 1.6e-08 33.3 2.7 1.6e-08 33.3 2.7 3.3 3 1 0 4 4 4 3 BT1 family DUF3540 PF12059.8 KDO22390.1 - 0.84 9.4 8.8 1.1 9.0 1.0 3.9 3 2 2 5 5 5 0 Protein of unknown function (DUF3540) PKD_channel PF08016.12 KDO22391.1 - 2e-05 23.5 12.0 0.00018 20.4 4.9 2.4 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KDO22391.1 - 7.6e-05 22.0 16.0 0.00017 20.9 15.7 1.7 1 1 0 1 1 1 1 Ion transport protein GST_C_3 PF14497.6 KDO22392.1 - 6.7e-13 48.7 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO22392.1 - 4e-08 33.5 0.0 6.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO22392.1 - 0.00025 21.2 0.1 0.00081 19.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO22392.1 - 0.02 15.2 0.1 0.038 14.3 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO22392.1 - 0.027 14.5 0.2 0.074 13.1 0.2 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KDO22392.1 - 0.042 14.4 0.1 0.072 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO22392.1 - 0.064 13.7 0.0 0.24 11.8 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO22393.1 - 9.2e-13 48.2 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO22393.1 - 4e-08 33.5 0.0 6.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO22393.1 - 0.0029 17.8 0.1 0.0092 16.2 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO22393.1 - 0.01 15.8 0.2 0.027 14.5 0.2 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KDO22393.1 - 0.02 15.5 0.1 0.034 14.7 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO22393.1 - 0.02 15.2 0.1 0.038 14.3 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO22393.1 - 0.064 13.7 0.0 0.24 11.8 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain Nexin_C PF08628.12 KDO22394.1 - 0.00086 19.9 0.0 0.0016 19.0 0.0 1.4 2 0 0 2 2 2 1 Sorting nexin C terminal DUF459 PF04311.13 KDO22394.1 - 0.18 10.8 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) PXA PF02194.15 KDO22395.1 - 1.4e-18 67.5 0.1 2.9e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 PXA domain RUN PF02759.19 KDO22395.1 - 0.0003 20.7 1.0 0.0011 18.9 1.0 2.0 1 1 0 1 1 1 1 RUN domain BRE1 PF08647.11 KDO22396.1 - 3.7e-11 43.0 10.9 3.7e-11 43.0 10.9 11.0 5 2 7 12 12 12 2 BRE1 E3 ubiquitin ligase GAS PF13851.6 KDO22396.1 - 0.0018 17.7 24.6 0.0018 17.7 24.6 7.8 1 1 4 6 6 6 1 Growth-arrest specific micro-tubule binding CENP-B_dimeris PF09026.10 KDO22396.1 - 0.11 12.9 10.1 0.32 11.4 10.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4551 PF15087.6 KDO22397.1 - 0.029 13.2 0.6 0.056 12.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LEF-4 PF05098.12 KDO22397.1 - 0.059 12.2 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 4 (LEF-4) Utp12 PF04003.12 KDO22400.1 - 7.7e-20 71.2 0.3 1.5e-19 70.3 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KDO22400.1 - 1.1e-09 38.8 5.8 0.64 11.0 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO22400.1 - 4.9e-08 33.2 0.2 0.51 10.7 0.1 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain US22 PF02393.16 KDO22400.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 US22 like PPP4R2 PF09184.11 KDO22400.1 - 2.7 7.5 21.8 3.1 7.3 2.3 2.1 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 KDO22400.1 - 2.9 6.0 20.0 0.12 10.5 5.1 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KDO22400.1 - 4.2 6.6 20.3 0.53 9.6 3.1 2.2 2 0 0 2 2 2 0 BUD22 KASH_CCD PF14662.6 KDO22401.1 - 0.0015 18.4 20.3 0.0015 18.4 20.3 3.6 1 1 2 3 3 2 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KDO22401.1 - 0.0086 16.1 12.1 0.0086 16.1 12.1 4.5 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KDO22401.1 - 0.013 15.7 15.4 0.013 15.7 15.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KDO22401.1 - 0.019 15.1 25.3 0.07 13.2 1.2 5.4 3 3 2 5 5 5 0 bZIP transcription factor JIP_LZII PF16471.5 KDO22401.1 - 0.038 14.1 1.7 0.038 14.1 1.7 6.2 3 1 1 5 5 5 0 JNK-interacting protein leucine zipper II YabA PF06156.13 KDO22401.1 - 0.27 11.9 38.6 2.5 8.8 8.8 5.1 2 1 2 4 4 4 0 Initiation control protein YabA HMMR_C PF15908.5 KDO22401.1 - 0.45 10.8 28.3 0.25 11.6 1.9 3.5 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal TRAF_BIRC3_bd PF16673.5 KDO22401.1 - 0.9 9.4 12.8 2.3 8.0 1.0 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Leu_zip PF15294.6 KDO22401.1 - 2.2 7.8 41.8 6.5 6.2 14.9 3.6 1 1 2 3 3 3 0 Leucine zipper HIP1_clath_bdg PF16515.5 KDO22401.1 - 3.1 8.5 49.0 0.072 13.7 7.2 4.5 1 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 KDO22401.1 - 4.4 6.3 36.0 0.79 8.7 17.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 KDO22401.1 - 5 7.4 24.0 0.95 9.7 1.1 5.6 5 1 1 6 6 6 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 KDO22401.1 - 5.1 7.6 13.7 4.8 7.7 5.3 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein SHE3 PF17078.5 KDO22401.1 - 5.2 6.7 35.3 0.29 10.8 3.5 4.4 1 1 3 4 4 4 0 SWI5-dependent HO expression protein 3 GIT_CC PF16559.5 KDO22401.1 - 8.9 6.3 31.7 1.8 8.5 3.0 5.4 4 2 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Astacin PF01400.24 KDO22402.1 - 1.2e-33 116.4 0.0 2.9e-33 115.1 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KDO22402.1 - 3.6e-05 23.7 0.1 0.93 9.3 0.2 3.2 3 0 0 3 3 3 2 Matrixin Peptidase_M66 PF10462.9 KDO22402.1 - 0.00031 19.8 1.1 0.00046 19.2 1.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.8 KDO22402.1 - 0.064 11.9 0.1 0.099 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 KDO22402.1 - 0.13 12.4 3.2 0.26 11.4 3.2 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KDO22402.1 - 0.16 12.5 0.9 0.29 11.7 0.9 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KDO22402.1 - 0.2 11.3 1.3 0.39 10.3 1.3 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like bVLRF1 PF18826.1 KDO22403.1 - 5.4e-49 165.9 0.1 1.1e-48 164.9 0.1 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_4 PF13637.6 KDO22403.1 - 7.9e-09 35.9 1.0 6e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) VATC PF18716.1 KDO22403.1 - 8.4e-09 35.2 1.5 2.6e-08 33.6 0.4 2.2 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_3 PF13606.6 KDO22403.1 - 1.7e-08 34.0 1.5 0.00023 21.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO22403.1 - 2e-08 34.7 0.1 4.4e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO22403.1 - 9.8e-08 32.1 6.1 2.1e-06 27.9 0.3 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KDO22403.1 - 2.2e-06 27.8 0.2 5.9e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) acVLRF1 PF18859.1 KDO22403.1 - 0.033 14.5 0.8 0.033 14.5 0.8 3.0 3 0 0 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor zf-MYND PF01753.18 KDO22403.1 - 0.099 12.8 0.8 0.28 11.3 0.8 1.7 1 0 0 1 1 1 0 MYND finger AKAP95 PF04988.12 KDO22403.1 - 0.32 11.2 1.7 1.9 8.7 0.1 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) PXA PF02194.15 KDO22403.1 - 0.45 10.5 1.6 0.51 10.3 0.2 1.8 2 0 0 2 2 2 0 PXA domain Sigma70_ner PF04546.13 KDO22403.1 - 2.6 7.9 11.7 0.29 11.0 2.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region FKBP_C PF00254.28 KDO22405.1 - 3.2e-29 101.1 0.0 4e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DHHC PF01529.20 KDO22406.1 - 3.6 7.7 10.4 2.1 8.4 0.5 2.1 1 1 0 2 2 2 0 DHHC palmitoyltransferase DUF2070 PF09843.9 KDO22406.1 - 6.5 4.9 13.4 10 4.3 13.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) CbiQ PF02361.16 KDO22406.1 - 6.8 6.2 11.5 1.5 8.4 3.0 2.2 1 1 1 2 2 2 0 Cobalt transport protein RINGv PF12906.7 KDO22407.1 - 1.6e-10 40.9 3.7 3e-10 40.0 3.7 1.5 1 0 0 1 1 1 1 RING-variant domain DUF179 PF02622.15 KDO22407.1 - 5.3e-06 26.5 0.0 1.8e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 Spc7_C2 PF15577.6 KDO22407.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Spc7_C2 FYVE PF01363.21 KDO22408.1 - 9.6e-12 44.9 27.4 9.9e-08 32.0 15.9 3.0 2 1 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 KDO22408.1 - 4.4e-06 27.4 0.4 1.2e-05 26.0 0.4 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KDO22408.1 - 6.7e-05 23.2 0.3 0.00014 22.2 0.3 1.5 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO22408.1 - 0.0078 16.4 14.9 0.042 14.1 9.2 2.8 3 0 0 3 3 3 1 FYVE-type zinc finger GAF_2 PF13185.6 KDO22408.1 - 0.015 15.6 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 GAF domain SpoVT_C PF15714.5 KDO22408.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor FYVE PF01363.21 KDO22409.1 - 9.1e-27 93.0 33.7 1.2e-14 54.2 11.5 2.4 2 0 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 KDO22409.1 - 1e-09 39.1 0.2 1.2e-08 35.7 0.1 2.6 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO22409.1 - 0.00071 19.8 23.7 0.043 14.0 6.7 2.6 2 0 0 2 2 2 2 FYVE-type zinc finger TruB_C_2 PF16198.5 KDO22409.1 - 0.03 14.5 0.3 3.7 7.8 0.0 2.9 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain IBR PF01485.21 KDO22409.1 - 2.3 8.5 19.8 9.3 6.6 7.3 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Methyltransf_11 PF08241.12 KDO22410.1 - 2.2e-19 69.9 0.0 6.3e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO22410.1 - 8.5e-18 64.9 0.0 2.6e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO22410.1 - 3.4e-11 43.2 0.0 8.5e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO22410.1 - 2.6e-07 31.3 0.0 5.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO22410.1 - 2.1e-06 27.6 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO22410.1 - 6.7e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KDO22410.1 - 0.00038 19.2 0.0 0.00049 18.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 KDO22410.1 - 0.002 17.5 0.0 0.0096 15.2 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Bin3 PF06859.12 KDO22410.1 - 0.043 14.4 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) MoaE PF02391.17 KDO22411.1 - 3.1e-39 133.8 0.4 3.6e-39 133.5 0.4 1.1 1 0 0 1 1 1 1 MoaE protein DciA PF05258.12 KDO22411.1 - 0.11 12.9 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA IBR PF01485.21 KDO22412.1 - 1e-13 51.3 31.9 3.6e-08 33.5 6.2 4.1 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KDO22412.1 - 6.4e-07 29.1 1.8 6.4e-07 29.1 1.8 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO22412.1 - 2.1e-06 28.0 2.0 2.1e-06 28.0 2.0 4.7 5 2 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KDO22412.1 - 1.3e-05 25.0 2.1 1.3e-05 25.0 2.1 4.7 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO22412.1 - 0.0004 20.5 3.0 0.0004 20.5 3.0 5.0 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO22412.1 - 0.0073 16.3 2.4 0.0073 16.3 2.4 4.8 3 1 2 5 5 5 1 zinc-RING finger domain Yip1 PF04893.17 KDO22412.1 - 0.63 9.7 4.4 1.1 8.9 4.4 1.3 1 0 0 1 1 1 0 Yip1 domain DENN PF02141.21 KDO22413.1 - 3.8e-21 75.9 3.7 7.4e-21 74.9 3.7 1.5 1 1 0 1 1 1 1 DENN (AEX-3) domain ENTH PF01417.20 KDO22413.1 - 2.1e-06 27.8 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain RhoGAP PF00620.27 KDO22414.1 - 3.6e-10 39.9 2.8 4.8e-08 33.0 2.2 2.5 2 0 0 2 2 2 2 RhoGAP domain DUF2267 PF10025.9 KDO22414.1 - 0.061 13.6 1.9 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) MCM PF00493.23 KDO22415.1 - 1.1e-96 322.3 0.0 1.9e-96 321.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KDO22415.1 - 2.2e-39 134.2 0.2 7.6e-39 132.4 0.1 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KDO22415.1 - 4.4e-27 94.3 1.8 1.1e-26 93.0 1.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KDO22415.1 - 2.1e-09 37.9 0.1 8.6e-09 35.9 0.0 2.1 2 0 0 2 2 1 1 MCM N-terminal domain AAA_5 PF07728.14 KDO22415.1 - 2.3e-07 30.9 0.0 7.1e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KDO22415.1 - 1e-06 28.3 0.1 0.00015 21.2 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KDO22415.1 - 0.00013 21.8 0.0 0.003 17.4 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KDO22415.1 - 0.0044 16.7 0.0 0.066 12.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Cytochrome_C7 PF14522.6 KDO22415.1 - 0.028 14.4 2.0 0.063 13.3 2.0 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 KDO22415.1 - 0.041 14.0 1.5 0.1 12.7 1.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain AAA_32 PF13654.6 KDO22415.1 - 0.074 11.8 0.5 0.23 10.2 0.6 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO22415.1 - 0.079 13.3 0.1 0.7 10.3 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_lid_2 PF17863.1 KDO22415.1 - 0.15 12.0 0.7 0.33 10.8 0.7 1.6 1 0 0 1 1 1 0 AAA lid domain Elf1 PF05129.13 KDO22415.1 - 0.32 11.1 1.0 0.72 9.9 1.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KDO22415.1 - 0.82 10.2 3.9 1.7 9.2 3.9 1.4 1 0 0 1 1 1 0 CHY zinc finger Ketoacyl-synt_C PF02801.22 KDO22417.1 - 7e-29 100.2 0.7 8.7e-29 99.9 0.7 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SPRY PF00622.28 KDO22418.1 - 3.1e-05 24.1 0.0 9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 SPRY domain SPRY PF00622.28 KDO22419.1 - 9.4e-08 32.2 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 SPRY domain ATP-grasp_5 PF13549.6 KDO22419.1 - 0.015 14.7 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Neuralized PF07177.12 KDO22419.1 - 0.019 14.9 0.0 0.02 14.9 0.0 1.3 1 1 0 1 1 1 0 Neuralized TcpQ PF10671.9 KDO22419.1 - 0.039 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q PAN_1 PF00024.26 KDO22422.1 - 4e-07 29.9 0.9 2.4e-06 27.4 0.2 2.2 1 1 1 2 2 2 1 PAN domain PAN_2 PF08276.11 KDO22422.1 - 0.0025 17.9 2.1 0.063 13.4 0.6 2.4 2 0 0 2 2 2 1 PAN-like domain PAN_3 PF08277.12 KDO22422.1 - 0.009 15.8 2.3 0.01 15.6 0.8 1.8 2 0 0 2 2 2 1 PAN-like domain PAN_4 PF14295.6 KDO22422.1 - 0.057 13.3 12.9 0.045 13.7 4.3 3.0 2 1 0 2 2 2 0 PAN domain Dimer_Tnp_hAT PF05699.14 KDO22423.1 - 6.5e-15 54.7 0.1 1.1e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Acyl_transf_3 PF01757.22 KDO22424.1 - 2.5e-15 56.4 44.2 3.2e-15 56.0 41.6 2.0 1 1 1 2 2 2 2 Acyltransferase family PAN_4 PF14295.6 KDO22425.1 - 3.1e-08 33.4 26.2 2.5e-05 24.1 5.0 4.4 4 0 0 4 4 4 3 PAN domain MANEC PF07502.14 KDO22425.1 - 0.036 14.3 3.2 0.88 9.9 0.3 2.7 2 0 0 2 2 2 0 MANEC domain Glyoxalase PF00903.25 KDO22427.1 - 5.9e-10 39.4 0.0 6.6e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO22427.1 - 0.0031 18.3 0.1 0.0036 18.1 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KDO22427.1 - 0.022 15.0 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Big_2 PF02368.18 KDO22427.1 - 0.054 13.4 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Glyoxalase_3 PF13468.6 KDO22427.1 - 0.074 13.2 0.0 0.83 9.7 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain TPR_7 PF13176.6 KDO22427.1 - 0.08 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.7 KDO22428.1 - 0.0016 18.3 0.4 0.0016 18.3 0.4 2.7 3 0 0 3 3 2 1 F-box-like zf-RING_11 PF17123.5 KDO22428.1 - 0.0029 17.3 0.7 0.0058 16.4 0.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger UPF0242 PF06785.11 KDO22428.1 - 0.01 15.9 22.9 0.01 15.9 22.9 1.7 2 1 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KDO22428.1 - 0.025 14.8 18.2 0.032 14.4 12.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KDO22428.1 - 0.026 13.9 28.5 0.55 9.5 7.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 KDO22428.1 - 0.06 12.8 18.2 0.094 12.2 18.2 1.3 1 0 0 1 1 1 0 Leucine zipper zf-C4H2 PF10146.9 KDO22428.1 - 0.15 12.4 9.2 0.26 11.6 9.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Pox_A_type_inc PF04508.12 KDO22428.1 - 0.39 10.7 10.9 0.29 11.1 1.1 3.9 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 KDO22428.1 - 0.4 10.9 33.0 0.34 11.1 15.5 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KDO22428.1 - 1.1 8.8 17.3 1.8 8.1 17.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4201 PF13870.6 KDO22428.1 - 1.2 8.8 21.6 3.1 7.5 18.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DHR10 PF18595.1 KDO22428.1 - 1.3 9.1 33.7 8.4 6.5 12.2 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 KDO22428.1 - 1.5 8.8 25.6 0.81 9.7 4.7 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KDO22428.1 - 1.7 7.5 28.4 4 6.2 24.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF5082 PF16888.5 KDO22428.1 - 1.9 8.8 17.6 6 7.2 10.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 KDO22428.1 - 2 8.9 11.6 2.1 8.9 4.6 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 KDO22428.1 - 2.1 7.1 27.0 3 6.6 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MscS_porin PF12795.7 KDO22428.1 - 2.1 7.8 34.7 7.1 6.1 26.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 KDO22428.1 - 2.4 5.6 28.1 3.3 5.1 28.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TRAF_BIRC3_bd PF16673.5 KDO22428.1 - 2.4 8.0 9.3 1.3 8.8 0.8 3.1 2 1 1 3 3 2 0 TNF receptor-associated factor BIRC3 binding domain Fez1 PF06818.15 KDO22428.1 - 3 8.3 25.2 0.36 11.3 20.5 1.8 1 1 1 2 2 2 0 Fez1 USP8_interact PF08941.10 KDO22428.1 - 4.4 7.1 15.6 1.3 8.8 4.6 2.3 2 0 0 2 2 2 0 USP8 interacting Phage_GP20 PF06810.11 KDO22428.1 - 4.9 6.9 24.2 2.2 8.1 19.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Prominin PF05478.11 KDO22428.1 - 6.8 4.5 9.4 9.5 4.0 9.4 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 KDO22428.1 - 7.9 5.0 15.8 4.7 5.7 13.0 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A CENP-H PF05837.12 KDO22428.1 - 9.1 6.7 28.3 14 6.1 15.7 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Rootletin PF15035.6 KDO22428.1 - 9.5 6.2 27.6 54 3.7 27.5 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF5624 PF18538.1 KDO22428.1 - 9.9 6.3 10.4 8.9 6.4 3.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5624) CorA PF01544.18 KDO22428.1 - 9.9 5.4 11.3 19 4.5 11.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ank_4 PF13637.6 KDO22429.1 - 1.2e-29 102.3 1.6 3e-09 37.2 0.0 4.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22429.1 - 2.6e-29 101.6 0.3 3.8e-13 49.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO22429.1 - 1.1e-22 79.8 0.1 4.9e-12 45.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22429.1 - 2.4e-20 70.5 0.4 9e-05 22.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO22429.1 - 1.5e-18 66.3 0.0 0.00016 22.0 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat HTH_Tnp_Tc5 PF03221.16 KDO22429.1 - 0.00042 20.3 0.3 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain FPN1 PF06963.12 KDO22431.1 - 2e-32 112.3 20.1 7e-18 64.4 7.6 2.3 1 1 1 2 2 2 2 Ferroportin1 (FPN1) Ank_2 PF12796.7 KDO22432.1 - 3.6e-24 85.2 4.6 2.4e-11 44.1 1.9 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22432.1 - 3.6e-22 78.4 10.0 2.6e-07 31.1 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22432.1 - 9e-16 56.4 0.6 0.012 16.1 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO22432.1 - 3.9e-15 55.5 5.3 0.037 14.5 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KDO22432.1 - 6.2e-14 51.9 2.2 5.8e-08 32.8 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DBD_Tnp_Mut PF03108.15 KDO22432.1 - 0.033 14.2 0.6 0.071 13.1 0.6 1.5 1 0 0 1 1 1 0 MuDR family transposase Acetyltransf_1 PF00583.25 KDO22433.1 - 3.5e-07 30.5 0.0 5.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO22433.1 - 3e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO22433.1 - 0.00021 21.6 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO22433.1 - 0.0011 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 KDO22433.1 - 0.021 15.0 0.6 0.021 15.0 0.6 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO22433.1 - 0.089 12.9 0.2 0.21 11.7 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KDO22437.1 - 1e-21 77.3 1.2 0.0015 19.1 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22437.1 - 3.8e-16 59.2 7.1 4.7e-05 23.9 0.2 5.7 4 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22437.1 - 6.1e-16 56.9 0.3 0.35 11.6 0.0 7.6 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KDO22437.1 - 2e-15 56.7 6.2 0.023 15.0 0.1 7.0 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO22437.1 - 0.00096 19.5 0.6 64 4.2 0.0 5.8 3 2 0 3 3 3 0 Ankyrin repeat DUF5049 PF16468.5 KDO22437.1 - 0.028 14.3 1.5 18 5.3 0.0 5.3 6 2 2 8 8 8 0 Domain of unknown function (DUF5049) Gpi16 PF04113.14 KDO22438.1 - 1.1e-97 327.8 1.1 2.3e-52 178.2 0.0 2.6 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component PliI PF16743.5 KDO22439.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme NAD_binding_1 PF00175.21 KDO22440.1 - 1.1e-13 51.8 0.0 2.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KDO22440.1 - 2.5e-10 40.6 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 KDO22440.1 - 9.2e-08 32.6 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 KDO22440.1 - 0.00081 19.5 0.0 0.029 14.5 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KDO22440.1 - 0.047 13.6 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Protoglobin NAD_binding_1 PF00175.21 KDO22442.1 - 7.9e-14 52.2 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KDO22442.1 - 2.8e-10 40.4 0.0 5.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 KDO22442.1 - 9.1e-08 32.6 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 KDO22442.1 - 0.0005 20.2 0.0 0.031 14.4 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KDO22442.1 - 0.049 13.5 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Protoglobin Trypan_PARP PF05887.11 KDO22443.1 - 0.007 16.4 13.8 0.011 15.7 13.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SKG6 PF08693.10 KDO22443.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GILT PF03227.16 KDO22444.1 - 2e-25 89.1 0.0 7.7e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 Gamma interferon inducible lysosomal thiol reductase (GILT) HECT PF00632.25 KDO22445.1 - 1e-58 199.2 0.0 2.7e-58 197.9 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-NADH-PPase PF09297.11 KDO22445.1 - 0.2 11.4 2.2 0.88 9.3 0.4 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 KDO22445.1 - 0.2 11.7 0.9 0.91 9.6 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon FRG1 PF06229.12 KDO22446.1 - 4.9e-09 36.2 0.0 0.027 14.2 0.0 3.4 1 1 1 3 3 3 3 FRG1-like domain Fascin PF06268.13 KDO22446.1 - 0.00023 21.3 0.0 4.4 7.6 0.0 3.7 2 2 1 3 3 3 2 Fascin domain CRAL_TRIO PF00650.20 KDO22447.1 - 7.3e-33 113.5 0.1 3.9e-31 107.9 0.1 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KDO22447.1 - 2.2e-07 31.1 0.1 3.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KDO22447.1 - 2.8e-07 30.6 0.4 7.2e-07 29.3 0.3 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Ribosomal_S15 PF00312.22 KDO22448.1 - 0.026 14.7 1.1 0.035 14.3 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S15 DUF4600 PF15372.6 KDO22448.1 - 0.061 13.8 7.7 0.12 12.8 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Golgin_A5 PF09787.9 KDO22448.1 - 0.36 10.3 14.6 0.46 9.9 14.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KDO22448.1 - 0.75 8.8 9.9 0.95 8.5 9.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-Q PF13094.6 KDO22448.1 - 1.6 8.9 19.3 5.8 7.1 19.1 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Acetyltransf_11 PF13720.6 KDO22448.1 - 1.7 9.2 4.3 1.9 9.0 1.8 2.4 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Lung_7-TM_R PF06814.13 KDO22450.1 - 5.8e-39 134.1 6.4 7e-39 133.8 6.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KDO22450.1 - 0.042 13.2 6.7 0.07 12.5 6.7 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF3087 PF11286.8 KDO22450.1 - 0.14 11.6 1.2 5.9 6.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) ABC2_membrane_3 PF12698.7 KDO22450.1 - 3.5 6.6 14.6 0.93 8.5 10.6 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein DENN PF02141.21 KDO22452.1 - 2.2e-24 86.4 0.6 4.6e-24 85.4 0.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain SlyX PF04102.12 KDO22452.1 - 0.78 10.4 4.3 19 5.9 0.1 2.7 2 0 0 2 2 2 0 SlyX DHHC PF01529.20 KDO22454.1 - 4.2e-21 75.5 13.4 5.4e-21 75.1 13.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase CAMSAP_CC1 PF17095.5 KDO22454.1 - 1.9 8.4 4.7 3.2 7.7 4.7 1.3 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin FKBP_C PF00254.28 KDO22455.1 - 4.5e-20 71.8 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Herpes_BTRF1 PF04682.12 KDO22455.1 - 0.12 11.7 0.6 0.21 10.9 0.6 1.4 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region Chorismate_bind PF00425.18 KDO22456.1 - 1.9e-86 289.8 0.0 2.6e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KDO22456.1 - 1.1e-38 133.0 0.0 2.1e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KDO22456.1 - 4e-17 62.7 0.0 2.9e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KDO22456.1 - 8.5e-12 45.3 0.0 2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Ceramidase PF05875.12 KDO22458.1 - 6.2e-54 183.2 15.7 7.8e-54 182.8 15.7 1.1 1 0 0 1 1 1 1 Ceramidase ECF_trnsprt PF12822.7 KDO22458.1 - 0.41 10.7 3.4 1.3 9.1 2.8 2.2 1 1 1 2 2 2 0 ECF transporter, substrate-specific component VHL PF01847.16 KDO22461.1 - 1.1e-19 70.2 0.3 5.6e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 VHL beta domain C2 PF00168.30 KDO22461.1 - 3.2e-12 46.6 0.0 1.1e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain PSCyt3 PF07627.11 KDO22463.1 - 0.11 12.7 0.1 0.54 10.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) Sin3a_C PF16879.5 KDO22464.1 - 2.9e-36 125.7 3.5 2.9e-36 125.7 3.5 3.2 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KDO22464.1 - 6.8e-36 122.3 0.0 2.3e-35 120.6 0.0 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KDO22464.1 - 4.5e-24 84.3 4.5 1.4e-17 63.6 2.9 2.9 2 0 0 2 2 2 2 Paired amphipathic helix repeat PP2C PF00481.21 KDO22465.1 - 2.8e-45 155.0 0.0 3.5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO22465.1 - 0.00026 21.0 2.9 0.29 11.0 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KDO22465.1 - 0.0091 15.7 0.2 0.028 14.1 0.2 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_hydro_20 PF00728.22 KDO22466.1 - 1.4e-89 301.0 0.2 1.7e-89 300.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KDO22466.1 - 3.2e-12 47.3 0.3 4.7e-11 43.5 0.3 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KDO22466.1 - 2.1e-05 25.3 0.5 0.00021 22.1 0.3 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 RecO_N_2 PF13114.6 KDO22466.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 RecO N terminal WXG100 PF06013.12 KDO22467.1 - 0.05 13.9 2.6 0.086 13.1 2.6 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG HECT PF00632.25 KDO22468.1 - 1.4e-81 274.4 0.0 1.8e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO22468.1 - 0.00071 18.8 1.3 0.0014 17.9 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KDO22468.1 - 0.13 12.4 2.0 0.16 12.1 0.5 1.9 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger LTD PF00932.19 KDO22469.1 - 0.00059 20.2 0.0 0.00093 19.5 0.0 1.2 1 0 0 1 1 1 1 Lamin Tail Domain Anoctamin PF04547.12 KDO22470.1 - 2.7e-79 267.1 13.6 3.4e-79 266.8 13.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel tRNA-synt_2d PF01409.20 KDO22471.1 - 2.4e-48 164.8 0.2 6.4e-48 163.4 0.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KDO22471.1 - 5.5e-24 84.4 0.0 1.6e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain CH PF00307.31 KDO22472.1 - 2.1e-36 124.4 0.0 1.1e-17 64.2 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CDC24 PF06395.11 KDO22472.1 - 2.8e-05 24.3 0.1 0.063 13.5 0.0 2.3 2 0 0 2 2 2 2 CDC24 Calponin TFIIA PF03153.13 KDO22472.1 - 3.4 7.6 6.3 5.1 7.0 6.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF73-100_C PF11718.8 KDO22474.1 - 4.1e-36 124.6 1.1 5.8e-35 120.8 1.1 2.3 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KDO22474.1 - 1.9e-31 108.6 0.0 5.7e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KDO22474.1 - 8.1e-23 80.9 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO22474.1 - 2.4e-19 70.1 0.2 5.6e-19 68.9 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KDO22474.1 - 3.3e-17 62.2 0.0 7.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KDO22474.1 - 1.3e-09 37.9 1.0 2.9e-09 36.7 0.2 2.0 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KDO22474.1 - 8.8e-06 25.1 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 KDO22474.1 - 8.9e-06 25.7 0.0 4.7e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CxC6 PF18721.1 KDO22475.1 - 0.0088 16.3 7.9 0.0088 16.3 7.9 3.9 1 1 2 3 3 3 2 CxC6 like cysteine cluster associated with KDZ transposases Aminotran_MocR PF12897.7 KDO22476.1 - 0.066 12.0 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase zf-RVT PF13966.6 KDO22479.1 - 3.6e-07 30.8 0.2 2e-06 28.4 0.0 2.1 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase CxC6 PF18721.1 KDO22480.1 - 3.7 7.9 31.1 2.1 8.7 1.6 4.1 1 1 2 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases DUF384 PF04064.13 KDO22483.1 - 0.0026 17.6 0.2 0.0045 16.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Ank_4 PF13637.6 KDO22488.1 - 3.6e-11 43.4 6.3 2.1e-05 25.0 0.5 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22488.1 - 1.7e-10 40.9 3.6 9e-05 22.7 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22488.1 - 2.9e-09 37.4 7.4 9e-05 23.0 1.4 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22488.1 - 3.2e-06 27.1 0.8 1 10.2 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KDO22488.1 - 0.03 14.8 4.1 0.59 10.7 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 KDO22489.1 - 2.4e-26 91.8 0.7 8.8e-11 42.1 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22489.1 - 3.9e-21 74.8 1.9 1.7e-11 44.1 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO22489.1 - 3.6e-17 61.9 7.0 9.1e-05 22.7 0.3 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KDO22489.1 - 4.9e-16 59.1 1.3 1.2e-09 38.6 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22489.1 - 2.2e-14 52.1 1.5 0.013 16.0 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat AI-2E_transport PF01594.16 KDO22491.1 - 6.7e-12 45.2 19.9 6.7e-12 45.2 19.9 3.1 3 0 0 3 3 3 1 AI-2E family transporter Peptidase_M13_N PF05649.13 KDO22492.1 - 2e-73 248.3 0.0 2.7e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO22492.1 - 2e-61 207.2 0.6 3.9e-61 206.2 0.6 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF1018 PF06252.12 KDO22492.1 - 0.19 12.7 0.6 5.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) FAD_binding_4 PF01565.23 KDO22494.1 - 5.9e-29 100.6 0.1 8.2e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain IQ PF00612.27 KDO22495.1 - 0.5 10.3 30.4 6.3 6.9 0.1 6.4 5 1 0 5 5 5 0 IQ calmodulin-binding motif EF-hand_7 PF13499.6 KDO22496.1 - 1.5e-19 70.2 0.0 7.5e-11 42.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO22496.1 - 1.5e-17 61.7 0.3 0.00038 19.8 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KDO22496.1 - 3.2e-15 54.7 0.0 0.00043 20.0 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KDO22496.1 - 1e-09 37.4 2.2 0.0031 16.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO22496.1 - 3.8e-08 33.0 0.1 0.00021 21.1 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair zf-B_box PF00643.24 KDO22496.1 - 0.032 14.4 21.1 0.5 10.6 5.6 2.5 2 0 0 2 2 2 0 B-box zinc finger CEBP_ZZ PF16366.5 KDO22496.1 - 0.23 11.7 18.9 0.7 10.2 4.6 2.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Ank_2 PF12796.7 KDO22497.1 - 4.4e-23 81.7 4.5 6.2e-05 23.5 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22497.1 - 4.3e-18 65.4 13.8 0.0028 18.2 0.2 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22497.1 - 1.1e-15 57.4 13.3 0.038 14.3 0.0 8.5 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22497.1 - 4.4e-13 48.1 8.6 3.4 8.5 0.0 10.3 12 0 0 12 12 12 2 Ankyrin repeat DUF5049 PF16468.5 KDO22497.1 - 0.0022 17.8 3.5 0.94 9.4 0.1 5.8 6 2 2 8 8 8 1 Domain of unknown function (DUF5049) DUF3322 PF11795.8 KDO22497.1 - 0.013 15.6 0.5 5.3 7.0 0.0 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank PF00023.30 KDO22497.1 - 0.033 14.6 12.1 19 5.9 0.1 7.5 5 3 2 7 7 7 0 Ankyrin repeat DUF1979 PF09322.10 KDO22497.1 - 0.093 12.7 0.1 4.6 7.2 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1979) B12D PF06522.11 KDO22498.1 - 2.3e-07 30.5 0.0 5.5e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Elicitin PF00964.17 KDO22498.1 - 1.1e-06 28.6 1.9 2e-06 27.8 1.9 1.5 1 0 0 1 1 1 1 Elicitin 2OG-FeII_Oxy_3 PF13640.6 KDO22499.1 - 9.1e-20 71.4 0.0 2.2e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KDO22499.1 - 4.9e-09 36.7 0.0 1.2e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MORN PF02493.20 KDO22500.1 - 1.1e-12 47.0 16.2 2.7e-06 26.9 1.2 4.4 4 0 0 4 4 4 4 MORN repeat 2OG-FeII_Oxy_3 PF13640.6 KDO22501.1 - 2e-10 41.4 0.0 2.9e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KDO22501.1 - 0.0026 18.2 0.0 0.018 15.5 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NuA4 PF09340.10 KDO22502.1 - 7e-14 51.5 0.0 1.6e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Glycoprotein_G PF00802.19 KDO22502.1 - 0.67 9.3 5.1 1.1 8.5 5.1 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Acyltransferase PF01553.21 KDO22503.1 - 1.1e-18 67.1 0.0 2.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.16 KDO22504.1 - 3.8e-08 32.6 43.2 0.00036 19.6 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KDO22504.1 - 9.3e-08 31.0 23.6 5.2e-07 28.6 10.1 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein DUF2427 PF10348.9 KDO22504.1 - 0.17 11.7 4.8 0.28 11.0 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Tweety PF04906.13 KDO22505.1 - 1.2e-14 53.9 3.6 1.8e-14 53.2 3.6 1.2 1 0 0 1 1 1 1 Tweety TMEM154 PF15102.6 KDO22505.1 - 0.11 12.3 0.1 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family CDP-OH_P_transf PF01066.21 KDO22507.1 - 8.6e-18 64.9 0.2 8.6e-18 64.9 0.2 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Abhydrolase_1 PF00561.20 KDO22509.1 - 1.4e-09 38.0 0.1 4e-09 36.5 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO22509.1 - 0.0018 17.6 0.0 0.77 9.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO22509.1 - 0.01 15.9 0.0 0.06 13.5 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein Glyco_transf_22 PF03901.17 KDO22510.1 - 2.5e-47 162.1 20.8 3.1e-47 161.8 20.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TMEM171 PF15471.6 KDO22511.1 - 0.048 12.7 2.5 0.053 12.5 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 ChAPs PF09295.10 KDO22511.1 - 0.15 11.0 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Gemini_C4 PF01492.17 KDO22513.1 - 0.07 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Geminivirus C4 protein FHA PF00498.26 KDO22514.1 - 3.2e-12 46.6 0.6 9.5e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 FHA domain TMF_DNA_bd PF12329.8 KDO22514.1 - 0.0018 18.2 2.1 0.0018 18.2 2.1 3.4 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KDO22514.1 - 0.0041 17.4 7.4 0.0041 17.4 7.4 3.5 4 0 0 4 4 4 2 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 KDO22514.1 - 0.078 12.3 27.1 0.6 9.4 12.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Tn7_Tnp_TnsA_C PF08721.11 KDO22514.1 - 0.2 12.3 4.3 0.2 12.3 0.4 2.6 1 1 1 2 2 2 0 TnsA endonuclease C terminal DUF2431 PF10354.9 KDO22514.1 - 1.7 8.9 4.8 2.1 8.6 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2431) ABC_tran_CTD PF16326.5 KDO22514.1 - 5.5 7.3 23.6 5.1 7.4 6.6 3.7 3 1 1 4 4 4 0 ABC transporter C-terminal domain DUF1664 PF07889.12 KDO22514.1 - 6.2 6.9 22.3 3.4 7.7 6.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KDO22514.1 - 6.4 6.6 26.1 3.8 7.3 7.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Filament PF00038.21 KDO22515.1 - 0.0031 17.2 77.8 0.023 14.3 4.3 7.4 1 1 3 6 6 6 5 Intermediate filament protein Golgin_A5 PF09787.9 KDO22515.1 - 3.9 6.9 81.4 0.26 10.7 11.4 6.1 2 1 3 5 5 5 0 Golgin subfamily A member 5 Ceramidase PF05875.12 KDO22518.1 - 5.5e-49 167.0 16.2 7.3e-49 166.6 16.2 1.1 1 0 0 1 1 1 1 Ceramidase DUF1453 PF07301.11 KDO22518.1 - 0.0011 19.0 3.1 0.68 9.9 0.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1453) Heme_oxygenase PF01126.20 KDO22519.1 - 6.2e-67 225.4 2.4 9.5e-67 224.8 2.4 1.3 1 0 0 1 1 1 1 Heme oxygenase Ceramidase PF05875.12 KDO22520.1 - 2.1e-50 171.6 8.9 2.7e-50 171.2 8.9 1.1 1 0 0 1 1 1 1 Ceramidase IspA PF04279.15 KDO22520.1 - 0.45 10.7 7.5 2.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Intracellular septation protein A Heme_oxygenase PF01126.20 KDO22521.1 - 1.5e-62 211.1 0.4 2e-62 210.6 0.4 1.2 1 0 0 1 1 1 1 Heme oxygenase HTH_Tnp_Tc5 PF03221.16 KDO22522.1 - 1.4e-17 63.5 0.0 6e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain MarR PF01047.22 KDO22522.1 - 0.00032 20.6 0.1 0.00084 19.2 0.1 1.7 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.13 KDO22522.1 - 0.00035 20.1 0.1 0.0009 18.8 0.1 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 KDO22522.1 - 0.00079 18.9 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.6 KDO22522.1 - 0.0008 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 KDO22522.1 - 0.00085 19.0 0.2 0.0023 17.7 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KDO22522.1 - 0.0012 18.2 0.7 0.0032 16.8 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KDO22522.1 - 0.0013 18.5 0.1 0.0039 16.9 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.19 KDO22522.1 - 0.0016 18.6 0.1 0.0039 17.4 0.0 1.6 1 1 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain LacI PF00356.21 KDO22522.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_29 PF13551.6 KDO22522.1 - 0.0036 17.3 0.1 0.0081 16.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KDO22522.1 - 0.0052 16.9 1.2 0.0097 16.0 0.1 2.1 3 0 0 3 3 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 KDO22522.1 - 0.0072 16.1 0.2 0.033 14.0 0.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_26 PF13443.6 KDO22522.1 - 0.01 16.3 0.1 0.032 14.7 0.1 1.8 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_11 PF08279.12 KDO22522.1 - 0.014 15.3 0.1 0.048 13.6 0.1 2.0 1 1 0 1 1 1 0 HTH domain HTH_10 PF04967.12 KDO22522.1 - 0.023 14.5 0.1 0.08 12.8 0.1 1.9 1 0 0 1 1 1 0 HTH DNA binding domain HTH_36 PF13730.6 KDO22522.1 - 0.026 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain R3H-assoc PF13902.6 KDO22522.1 - 0.027 14.8 0.1 0.068 13.6 0.1 1.6 1 0 0 1 1 1 0 R3H-associated N-terminal domain THOC7 PF05615.13 KDO22522.1 - 0.028 14.7 0.4 0.67 10.2 0.0 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 YdaS_antitoxin PF15943.5 KDO22522.1 - 0.032 14.1 0.2 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 KDO22522.1 - 0.035 14.0 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 1 0 MarR family TrmB PF01978.19 KDO22522.1 - 0.036 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_50 PF18024.1 KDO22522.1 - 0.055 13.1 0.4 0.12 12.0 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KDO22522.1 - 0.096 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Crp_2 PF13545.6 KDO22522.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 KDO22522.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 MORN PF02493.20 KDO22523.1 - 7.8e-21 72.7 20.1 3.4e-08 32.9 0.7 6.9 8 0 0 8 8 8 5 MORN repeat Cwf_Cwc_15 PF04889.12 KDO22524.1 - 1.3e-67 228.2 22.0 1.9e-67 227.6 22.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GTP-bdg_M PF16360.5 KDO22524.1 - 0.016 15.8 1.6 0.016 15.8 1.6 2.3 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region ALMT PF11744.8 KDO22524.1 - 0.035 12.9 2.6 0.042 12.7 2.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Mit_KHE1 PF10173.9 KDO22524.1 - 0.08 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Glypican PF01153.19 KDO22524.1 - 0.88 8.3 4.7 1.1 8.0 4.7 1.1 1 0 0 1 1 1 0 Glypican rRNA_processing PF08524.11 KDO22524.1 - 0.89 9.6 15.7 1.8 8.6 15.7 1.5 1 0 0 1 1 1 0 rRNA processing RRN3 PF05327.11 KDO22524.1 - 1.3 7.5 12.3 1.4 7.4 12.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KDO22524.1 - 2.1 6.5 18.5 2.5 6.3 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KDO22524.1 - 3.8 7.2 16.8 5.1 6.7 16.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CRA PF06589.11 KDO22524.1 - 4.9 7.3 7.7 13 5.9 7.7 1.8 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) MIF4G PF02854.19 KDO22525.1 - 1.3e-17 64.1 0.1 4.3e-17 62.5 0.0 1.9 1 1 1 2 2 2 1 MIF4G domain MA3 PF02847.17 KDO22525.1 - 1e-14 54.4 0.2 3.2e-14 52.9 0.2 1.9 1 0 0 1 1 1 1 MA3 domain CENP-B_dimeris PF09026.10 KDO22525.1 - 0.042 14.2 5.6 0.19 12.1 5.6 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KDO22525.1 - 0.62 9.7 2.7 2.9 7.5 1.0 2.6 2 0 0 2 2 2 0 FAM176 family DUF5523 PF17661.1 KDO22525.1 - 0.75 9.4 6.5 0.05 13.3 0.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5523) CDC50 PF03381.15 KDO22526.1 - 4.9e-86 288.7 0.0 7.6e-86 288.1 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.15 KDO22527.1 - 8.3e-83 278.1 0.0 1.2e-82 277.6 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PP2C PF00481.21 KDO22528.1 - 2.5e-67 227.3 0.0 2.8e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO22528.1 - 6.9e-07 29.1 0.1 6.7e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KDO22529.1 - 3.9e-67 226.6 0.0 4.4e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO22529.1 - 4.6e-08 33.0 0.0 1.2e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO22529.1 - 0.0011 19.0 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) TPR_1 PF00515.28 KDO22530.1 - 5.1e-41 136.9 27.6 4e-09 35.9 0.3 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22530.1 - 3.3e-40 133.0 30.8 6.6e-07 29.0 0.6 10.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KDO22530.1 - 1.1e-34 118.8 25.3 6.9e-10 39.4 0.6 7.4 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22530.1 - 6.4e-29 97.7 12.2 0.0016 18.5 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO22530.1 - 4.5e-28 97.3 21.5 3.6e-16 59.1 0.0 6.0 3 1 6 9 9 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KDO22530.1 - 8.2e-27 93.5 19.6 0.00022 21.7 0.2 8.7 5 2 2 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22530.1 - 2.7e-24 83.8 29.9 0.0064 17.2 0.0 10.9 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22530.1 - 1.9e-21 76.2 36.6 7.5e-05 22.9 2.0 9.3 6 3 3 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KDO22530.1 - 5.4e-19 67.6 14.9 6.3e-06 25.8 0.8 8.5 6 1 4 10 10 9 5 TPR repeat TPR_17 PF13431.6 KDO22530.1 - 4.3e-17 61.2 18.0 0.001 19.3 0.0 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22530.1 - 6.4e-17 60.3 25.6 0.0073 16.3 0.0 10.2 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 KDO22530.1 - 1e-11 44.6 23.5 0.71 10.6 0.4 10.1 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 KDO22530.1 - 2e-08 34.0 19.8 2 9.3 0.1 7.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22530.1 - 5.3e-06 26.1 32.8 0.1 12.5 0.1 9.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_15 PF13429.6 KDO22530.1 - 4.2e-05 22.9 6.4 0.023 13.9 0.0 4.9 4 2 1 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KDO22530.1 - 9.4e-05 22.4 2.0 0.28 11.2 0.3 3.0 3 0 0 3 3 3 2 Putative TPR-like repeat TPR_20 PF14561.6 KDO22530.1 - 9.6e-05 22.6 5.8 0.0019 18.5 1.6 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 KDO22530.1 - 9.9e-05 22.1 6.2 0.00084 19.1 1.3 4.0 2 1 3 5 5 5 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KDO22530.1 - 0.0014 18.8 18.3 0.0015 18.6 0.1 5.7 5 2 2 8 8 7 1 Tetratricopeptide repeat DUF2225 PF09986.9 KDO22530.1 - 0.0016 18.2 0.7 3.3 7.4 0.2 4.1 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) Herpes_ICP4_N PF03584.15 KDO22530.1 - 0.028 14.3 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region HrpB1_HrpK PF09613.10 KDO22530.1 - 0.043 13.4 0.7 0.43 10.2 0.2 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 KDO22530.1 - 0.2 12.1 14.1 2.1 8.8 1.5 4.8 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Baculo_PEP_C PF04513.12 KDO22532.1 - 0.0015 18.6 1.7 0.081 13.0 0.1 2.4 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 KDO22532.1 - 0.0094 16.0 1.4 0.72 9.9 0.1 3.3 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 BMFP PF04380.13 KDO22532.1 - 0.02 15.3 1.2 0.1 13.1 0.2 2.6 2 1 1 3 3 3 0 Membrane fusogenic activity ACP_PD PF04336.12 KDO22532.1 - 0.022 15.1 1.5 37 4.8 0.0 3.2 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase DUF2205 PF10224.9 KDO22532.1 - 0.031 14.3 1.9 0.67 10.0 0.1 3.2 4 0 0 4 4 4 0 Short coiled-coil protein NPV_P10 PF05531.12 KDO22532.1 - 0.033 14.6 1.4 0.52 10.8 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 KDO22532.1 - 0.05 13.3 1.5 0.11 12.1 0.6 2.0 2 1 1 3 3 3 0 LXG domain of WXG superfamily Apolipoprotein PF01442.18 KDO22532.1 - 0.056 13.3 2.1 0.11 12.3 0.6 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MitMem_reg PF13012.6 KDO22532.1 - 0.07 13.6 0.5 0.92 10.0 0.3 2.7 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function SlyX PF04102.12 KDO22532.1 - 0.17 12.5 0.2 0.17 12.5 0.2 2.8 4 0 0 4 4 4 0 SlyX Ge1_WD40 PF16529.5 KDO22533.1 - 1.4e-12 47.3 0.0 8.6e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KDO22533.1 - 7.3e-09 36.1 0.9 0.0034 18.2 0.2 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO22533.1 - 0.004 17.4 0.1 0.97 9.8 0.0 2.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3246 PF11596.8 KDO22533.1 - 0.18 11.2 1.6 0.34 10.3 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Mannosyl_trans3 PF11051.8 KDO22534.1 - 8.1e-30 104.1 0.1 2e-24 86.4 0.4 3.2 2 1 0 2 2 2 2 Mannosyltransferase putative TPR_2 PF07719.17 KDO22538.1 - 8.3e-18 63.0 2.2 1.6e-08 34.0 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22538.1 - 1.2e-16 59.7 0.3 3.8e-08 32.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Prefoldin PF02996.17 KDO22538.1 - 2.1e-15 56.7 0.2 2.1e-15 56.7 0.2 2.1 2 0 0 2 2 2 1 Prefoldin subunit TPR_8 PF13181.6 KDO22538.1 - 4.1e-13 48.4 0.1 1.6e-05 24.7 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO22538.1 - 2.4e-08 34.0 1.2 0.0019 18.3 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO22538.1 - 3.2e-08 33.1 0.3 0.0024 17.5 0.1 3.5 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 KDO22538.1 - 2.4e-07 31.3 6.9 0.012 16.3 3.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22538.1 - 2.4e-06 27.8 3.6 4.1e-05 23.8 0.4 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22538.1 - 1.6e-05 25.3 7.5 0.0014 19.2 1.1 4.0 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22538.1 - 4.7e-05 23.1 0.5 0.023 14.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO22538.1 - 0.0017 18.5 0.2 0.0045 17.2 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KDO22538.1 - 0.0018 18.1 7.1 0.072 13.0 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat NPV_P10 PF05531.12 KDO22538.1 - 0.0042 17.5 1.1 0.62 10.6 0.2 2.7 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein TPR_17 PF13431.6 KDO22538.1 - 0.0043 17.3 0.3 11 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO22538.1 - 0.0097 16.4 8.3 1.5 9.4 3.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KDO22538.1 - 0.012 15.0 0.4 3.4 7.2 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR TPR_4 PF07721.14 KDO22538.1 - 0.013 16.0 0.1 0.059 14.0 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3856 PF12968.7 KDO22538.1 - 0.032 14.3 0.7 0.78 9.8 0.2 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) U3_assoc_6 PF08640.11 KDO22538.1 - 0.049 13.7 2.4 0.17 12.0 2.4 1.9 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Prefoldin_3 PF13758.6 KDO22538.1 - 0.31 11.1 0.0 0.31 11.1 0.0 3.0 3 1 0 3 3 3 0 Prefoldin subunit TPR_6 PF13174.6 KDO22538.1 - 0.62 10.8 0.1 0.62 10.8 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat CCDC-167 PF15188.6 KDO22538.1 - 4.3 7.7 8.8 1.7 9.0 2.8 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DNA_primase_S PF01896.19 KDO22539.1 - 4.9e-56 189.6 0.4 7e-56 189.1 0.4 1.2 1 0 0 1 1 1 1 DNA primase small subunit KIP1 PF07765.12 KDO22539.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 KIP1-like protein Hist_deacetyl PF00850.19 KDO22540.1 - 8.3e-84 281.7 0.0 1.3e-83 281.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Hist_deacetyl PF00850.19 KDO22541.1 - 2.5e-82 276.8 0.2 3.3e-82 276.4 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PEP_mutase PF13714.6 KDO22542.1 - 1.6e-53 181.6 0.1 1.8e-53 181.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KDO22542.1 - 4.3e-13 48.6 0.4 5.5e-13 48.3 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KDO22542.1 - 0.00066 19.1 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase RFC1 PF08519.12 KDO22543.1 - 8.1e-38 130.1 0.0 1.6e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KDO22543.1 - 1.9e-12 47.4 0.0 9.5e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KDO22543.1 - 7.8e-12 45.8 0.1 1.9e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO22543.1 - 2.7e-05 24.0 0.0 5.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KDO22543.1 - 5.8e-05 22.9 1.0 0.00015 21.5 1.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KDO22543.1 - 0.00026 21.0 0.0 0.00069 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO22543.1 - 0.0007 19.9 0.2 0.0058 16.9 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KDO22543.1 - 0.0014 19.1 0.2 0.0046 17.4 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KDO22543.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KDO22543.1 - 0.0057 16.6 0.1 0.028 14.4 0.1 2.0 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KDO22543.1 - 0.0081 16.1 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 NTPase TIP49 PF06068.13 KDO22543.1 - 0.0094 15.2 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DNA_pol3_delta PF06144.13 KDO22543.1 - 0.012 15.5 0.0 0.047 13.5 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KDO22543.1 - 0.019 14.4 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 KDO22543.1 - 0.023 14.4 0.3 7.3 6.3 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KDO22543.1 - 0.025 14.3 0.2 0.095 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KDO22543.1 - 0.026 14.5 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KDO22543.1 - 0.036 13.4 0.0 0.086 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KDO22543.1 - 0.039 14.3 0.0 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 KDO22543.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO22543.1 - 0.072 12.3 0.1 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KDO22543.1 - 0.08 12.5 0.5 0.29 10.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KDO22543.1 - 0.088 12.7 0.0 0.36 10.7 0.0 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KDO22543.1 - 0.11 12.2 0.2 0.37 10.5 0.2 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 KDO22543.1 - 0.15 12.4 0.3 2.5 8.4 0.5 2.4 1 1 1 2 2 2 0 AAA domain DUF241 PF03087.14 KDO22543.1 - 0.39 10.5 0.0 0.39 10.5 0.0 2.7 4 0 0 4 4 3 0 Arabidopsis protein of unknown function JmjC PF02373.22 KDO22544.1 - 4.6e-19 68.9 0.0 9.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KDO22544.1 - 4.3e-15 56.1 0.3 1.6e-13 51.0 0.3 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO22544.1 - 0.0085 15.6 0.1 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 KDO22544.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Cupin domain BCNT PF07572.12 KDO22545.1 - 1.1e-25 89.4 2.7 1.1e-25 89.4 2.7 2.5 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF1018 PF06252.12 KDO22545.1 - 0.11 13.4 4.8 0.15 13.1 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) PDZ_6 PF17820.1 KDO22546.1 - 0.00017 21.3 0.3 0.0003 20.6 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO22546.1 - 0.006 16.9 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain fn3 PF00041.21 KDO22546.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO22546.1 - 0.015 15.9 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain PDZ_2 PF13180.6 KDO22546.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PhoD_N PF16655.5 KDO22546.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain HECT PF00632.25 KDO22547.1 - 1.2e-62 212.2 0.0 9e-62 209.3 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO22547.1 - 0.0011 18.2 2.6 0.0024 17.1 2.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Lyase_aromatic PF00221.19 KDO22548.1 - 1.1e-190 634.3 3.3 1.4e-190 633.9 3.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Sclerostin PF05463.11 KDO22548.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) Pkinase PF00069.25 KDO22549.1 - 5e-69 232.6 0.0 8e-69 231.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22549.1 - 8.8e-28 97.3 0.6 2.9e-19 69.4 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO22549.1 - 5.4e-05 22.3 0.0 0.00017 20.7 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO22549.1 - 0.00014 21.3 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO22549.1 - 0.00022 20.7 0.2 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family OmpH PF03938.14 KDO22550.1 - 0.004 17.5 31.3 0.078 13.3 10.8 2.2 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) BtrH_N PF14399.6 KDO22550.1 - 0.25 11.6 1.8 0.36 11.1 0.2 2.0 2 1 0 3 3 3 0 Butirosin biosynthesis protein H, N-terminal DUF4407 PF14362.6 KDO22550.1 - 0.34 10.2 24.8 0.042 13.2 13.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2586 PF10758.9 KDO22550.1 - 0.4 9.8 6.2 0.45 9.7 5.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2586) Jnk-SapK_ap_N PF09744.9 KDO22550.1 - 0.86 9.8 36.7 1.1 9.5 12.5 2.7 2 2 0 2 2 2 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 KDO22550.1 - 2.5 8.7 13.7 51 4.5 0.6 3.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CorA PF01544.18 KDO22550.1 - 5.9 6.1 18.7 0.086 12.1 9.0 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 KDO22550.1 - 8.9 6.4 17.9 0.39 10.8 0.3 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DDE_Tnp_1_6 PF13751.6 KDO22550.1 - 9.8 6.4 8.8 22 5.3 1.7 2.4 2 0 0 2 2 2 0 Transposase DDE domain Ribosomal_L11_N PF03946.14 KDO22551.1 - 3.3e-20 71.7 0.3 5.6e-20 71.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KDO22551.1 - 4.9e-16 59.0 0.1 8.1e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ig_3 PF13927.6 KDO22552.1 - 2.5e-06 28.0 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KDO22552.1 - 6.5e-05 23.2 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KDO22552.1 - 0.0011 18.9 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain PKD PF00801.20 KDO22552.1 - 0.0037 17.1 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 PKD domain Receptor_2B4 PF11465.8 KDO22552.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Big_5 PF13205.6 KDO22554.1 - 0.12 13.1 0.0 0.18 12.5 0.0 1.3 1 1 0 1 1 1 0 Bacterial Ig-like domain PseudoU_synth_1 PF01416.20 KDO22555.1 - 4.2e-15 56.1 0.1 5.2e-12 46.2 0.1 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase SelR PF01641.18 KDO22556.1 - 8.7e-49 164.6 0.3 9.9e-49 164.5 0.3 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KDO22556.1 - 0.0016 18.2 0.1 0.064 13.0 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein GFA PF04828.14 KDO22556.1 - 0.062 13.6 1.1 0.91 9.9 0.1 2.1 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 KDO22556.1 - 0.11 12.7 0.3 0.36 11.1 0.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KDO22557.1 - 3.1e-50 169.3 0.2 3.4e-50 169.2 0.2 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KDO22557.1 - 0.011 15.4 0.3 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ADD_ATRX PF17981.1 KDO22557.1 - 0.11 12.4 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Cysteine Rich ADD domain Yippee-Mis18 PF03226.14 KDO22557.1 - 0.2 11.9 0.8 3.8 7.8 0.8 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RVT PF13966.6 KDO22559.1 - 0.065 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase APG6_N PF17675.1 KDO22561.1 - 0.0076 16.8 4.2 0.0087 16.6 4.2 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KDO22561.1 - 0.015 15.3 1.5 0.018 15.0 1.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KDO22561.1 - 0.018 13.9 1.6 0.021 13.7 1.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Osmo_CC PF08946.10 KDO22561.1 - 0.02 15.2 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DivIC PF04977.15 KDO22561.1 - 0.096 12.5 0.7 0.096 12.5 0.7 1.4 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 KDO22561.1 - 0.12 11.7 1.7 0.12 11.7 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KDO22561.1 - 0.18 12.3 1.8 0.23 11.9 1.8 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) zf-RING_2 PF13639.6 KDO22563.1 - 2.7e-10 40.4 6.0 2.7e-10 40.4 6.0 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO22563.1 - 4.6e-08 32.8 5.0 1.1e-07 31.6 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22563.1 - 4.8e-08 33.2 2.5 4.8e-08 33.2 2.5 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO22563.1 - 2.5e-07 30.3 2.2 2.5e-07 30.3 2.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO22563.1 - 2.3e-05 24.3 3.4 4.9e-05 23.2 3.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO22563.1 - 7.7e-05 22.5 4.0 0.00014 21.6 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO22563.1 - 0.0012 18.7 2.4 0.0024 17.7 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22563.1 - 0.016 15.2 3.8 0.037 14.1 3.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KDO22563.1 - 0.017 15.1 3.1 0.017 15.1 3.1 1.8 2 0 0 2 2 2 0 Zinc-finger zf-ANAPC11 PF12861.7 KDO22563.1 - 0.04 14.0 0.7 0.11 12.5 0.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KDO22563.1 - 0.052 13.5 3.9 0.065 13.2 1.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KDO22563.1 - 0.18 11.5 2.2 0.43 10.2 2.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KDO22563.1 - 1.2 9.1 3.6 2.8 7.9 3.6 1.6 1 0 0 1 1 1 0 PHD-finger DUF445 PF04286.12 KDO22564.1 - 7.2e-14 52.4 2.8 2e-08 34.4 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF445) Lact-deh-memb PF09330.11 KDO22564.1 - 0.19 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Exo_endo_phos PF03372.23 KDO22565.1 - 1.1e-22 80.8 0.2 1.6e-22 80.2 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HEAT_2 PF13646.6 KDO22566.1 - 0.0087 16.4 0.2 0.0087 16.4 0.2 7.1 6 2 2 8 8 8 2 HEAT repeats Cnd1 PF12717.7 KDO22566.1 - 0.025 14.6 10.5 0.075 13.1 0.3 5.0 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KDO22566.1 - 7.9 7.0 12.0 6.2 7.4 0.0 6.2 7 0 0 7 7 7 0 HEAT repeat Cupin_8 PF13621.6 KDO22567.1 - 1.2e-10 41.6 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO22567.1 - 2.3e-09 37.2 0.4 1.4e-08 34.6 0.4 2.2 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 KDO22567.1 - 0.00058 19.5 0.0 0.00058 19.5 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Peptidase_C48 PF02902.19 KDO22569.1 - 1.2e-08 35.0 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Trypan_PARP PF05887.11 KDO22569.1 - 0.006 16.6 12.5 0.55 10.2 11.8 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) PT PF04886.12 KDO22569.1 - 5.3 6.7 15.0 6.2e+03 -3.1 15.0 3.6 1 1 0 1 1 1 0 PT repeat RNase_T PF00929.24 KDO22571.1 - 0.077 13.5 0.7 7.1 7.1 0.3 2.3 2 0 0 2 2 2 0 Exonuclease PXA PF02194.15 KDO22571.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 PXA domain Requiem_N PF14051.6 KDO22572.1 - 0.028 14.6 0.0 0.093 12.9 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. PhoD PF09423.10 KDO22573.1 - 5.8e-23 81.5 0.3 2.9e-21 75.9 0.3 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase PAP2 PF01569.21 KDO22574.1 - 4e-23 81.7 7.9 8.4e-23 80.6 7.9 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF5426 PF17473.2 KDO22574.1 - 0.055 13.7 2.1 0.95 9.7 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5426) PAP2_3 PF14378.6 KDO22574.1 - 1.6 8.4 16.8 0.81 9.3 1.1 2.7 2 1 1 3 3 3 0 PAP2 superfamily EamA PF00892.20 KDO22574.1 - 3.8 7.7 10.9 0.19 11.9 3.4 2.6 3 1 0 3 3 3 0 EamA-like transporter family PAP2 PF01569.21 KDO22575.1 - 8.8e-23 80.6 3.9 8.8e-23 80.6 3.9 1.7 2 1 0 2 2 2 1 PAP2 superfamily MNHE PF01899.16 KDO22575.1 - 0.31 10.8 0.1 0.31 10.8 0.1 2.2 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit Fez1 PF06818.15 KDO22576.1 - 0.0034 17.9 35.4 0.16 12.4 13.0 2.6 2 1 0 2 2 2 2 Fez1 HMMR_N PF15905.5 KDO22576.1 - 0.015 14.8 39.5 0.19 11.1 9.1 2.6 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 KDO22576.1 - 0.022 15.0 32.6 0.048 13.9 0.2 4.9 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 KDO22576.1 - 0.083 10.4 38.2 0.1 10.1 38.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF641 PF04859.12 KDO22576.1 - 0.42 11.0 29.5 1.2 9.5 3.3 4.7 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) DUF4047 PF13256.6 KDO22576.1 - 1.5 9.0 5.9 0.29 11.3 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) MAD PF05557.13 KDO22576.1 - 1.6 7.0 37.2 0.013 13.9 19.2 2.5 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF16 PF01519.16 KDO22576.1 - 4.7 7.8 28.8 5.9 7.4 3.8 4.9 1 1 2 4 4 4 0 Protein of unknown function DUF16 DUF3251 PF11622.8 KDO22576.1 - 5.3 6.7 11.1 1.5 8.4 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3251) zf-BED PF02892.15 KDO22577.1 - 7.2e-08 32.3 7.7 0.00068 19.6 0.5 2.5 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.15 KDO22577.1 - 0.0036 17.2 3.1 0.08 12.9 0.2 2.4 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain Headcase PF16002.5 KDO22577.1 - 0.0075 15.7 0.3 4.3 6.8 0.1 2.4 2 0 0 2 2 2 2 Headcase protein zf-HC2 PF13490.6 KDO22577.1 - 0.12 12.6 1.6 5.4 7.4 0.2 3.2 2 0 0 2 2 2 0 Putative zinc-finger Zn_Tnp_IS1595 PF12760.7 KDO22577.1 - 0.24 11.4 4.2 6.3 6.9 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.12 KDO22577.1 - 0.51 10.9 8.6 1.2 9.7 1.9 2.6 2 0 0 2 2 2 0 CHY zinc finger zf-C2H2_2 PF12756.7 KDO22577.1 - 1.6 9.1 9.4 6.6 7.1 0.9 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KDO22577.1 - 1.8 9.1 8.5 7.2 7.2 0.5 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Lipase_3 PF01764.25 KDO22578.1 - 1.1e-08 35.0 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DFP PF04127.15 KDO22578.1 - 8.2e-07 29.0 0.0 0.00012 22.0 0.0 2.4 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Thioesterase PF00975.20 KDO22578.1 - 0.00099 19.3 0.5 0.005 17.0 0.0 2.3 3 0 0 3 3 3 1 Thioesterase domain DUF4848 PF16140.5 KDO22578.1 - 0.14 11.7 0.3 0.54 9.8 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4848) Myb_DNA-binding PF00249.31 KDO22579.1 - 1.3e-05 25.2 0.0 0.0055 16.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Troponin PF00992.20 KDO22579.1 - 0.38 11.1 3.4 13 6.0 0.5 2.4 2 0 0 2 2 2 0 Troponin VMA21 PF09446.10 KDO22580.1 - 1.1e-15 57.5 6.2 1.4e-15 57.1 6.2 1.2 1 0 0 1 1 1 1 VMA21-like domain Sbt_1 PF05982.12 KDO22580.1 - 0.031 13.6 0.7 0.035 13.4 0.7 1.1 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily DUF2976 PF11190.8 KDO22580.1 - 0.094 12.5 1.1 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF485 PF04341.12 KDO22580.1 - 0.11 12.4 2.5 0.15 12.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 JAB PF01398.21 KDO22581.1 - 3.3e-14 52.9 0.0 1.2e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KDO22581.1 - 3.3e-10 40.2 2.9 7.3e-10 39.0 2.9 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KDO22581.1 - 0.00011 22.0 0.0 0.00039 20.2 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain AIM5 PF17050.5 KDO22581.1 - 7 7.5 6.8 1.6 9.6 0.8 2.9 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 PEGA PF08308.11 KDO22582.1 - 0.22 11.4 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 PEGA domain V-SNARE PF05008.15 KDO22583.1 - 4.1e-15 55.9 3.6 4.1e-15 55.9 3.6 1.9 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KDO22583.1 - 2e-07 31.2 2.8 2e-07 31.2 2.8 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KDO22583.1 - 2.3e-07 30.7 7.0 4.4e-06 26.5 0.2 3.6 1 1 2 4 4 4 1 Sec20 Tropomyosin PF00261.20 KDO22583.1 - 0.00043 19.7 10.1 0.013 14.9 1.1 2.1 2 0 0 2 2 2 2 Tropomyosin DUF1664 PF07889.12 KDO22583.1 - 0.0014 18.7 9.3 0.12 12.4 0.7 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KDO22583.1 - 0.0068 16.5 8.5 0.01 15.9 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 KDO22583.1 - 0.0084 15.5 4.1 0.01 15.2 4.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KDO22583.1 - 0.013 15.5 10.3 0.16 11.9 0.7 2.6 2 1 0 2 2 2 0 Laminin Domain II PRT_C PF08372.10 KDO22583.1 - 0.022 14.5 0.4 1.4 8.6 0.0 2.4 2 1 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Synaptobrevin PF00957.21 KDO22583.1 - 0.036 13.9 0.2 0.036 13.9 0.2 2.0 2 0 0 2 2 2 0 Synaptobrevin TOM20_plant PF06552.12 KDO22583.1 - 0.071 12.8 0.5 0.66 9.7 0.0 2.1 1 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 RGS12_us1 PF16613.5 KDO22583.1 - 0.075 13.4 1.0 0.2 12.0 1.0 1.7 1 0 0 1 1 1 0 Unstructured region of RGS12 AAA_13 PF13166.6 KDO22583.1 - 0.077 11.6 8.5 0.11 11.1 8.5 1.2 1 0 0 1 1 1 0 AAA domain PilJ PF13675.6 KDO22583.1 - 0.079 13.0 3.6 0.16 12.0 2.6 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2408 PF10303.9 KDO22583.1 - 0.081 13.5 5.4 0.19 12.3 5.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) HrpB7 PF09486.10 KDO22583.1 - 0.086 13.2 11.6 0.24 11.8 3.3 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4208 PF13907.6 KDO22583.1 - 0.14 12.6 3.7 0.15 12.5 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) Spc7 PF08317.11 KDO22583.1 - 0.15 10.9 10.3 0.2 10.5 10.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KDO22583.1 - 0.16 12.5 3.8 2.2 8.8 1.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RPW8 PF05659.11 KDO22583.1 - 0.18 11.5 4.1 0.2 11.4 1.9 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Exonuc_VII_L PF02601.15 KDO22583.1 - 0.18 11.4 10.5 0.3 10.6 10.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit ZnuA PF01297.17 KDO22583.1 - 0.28 10.6 2.3 0.53 9.6 2.0 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Cauli_AT PF03233.13 KDO22583.1 - 0.39 10.6 4.9 0.95 9.4 1.8 2.1 2 0 0 2 2 2 0 Aphid transmission protein XhlA PF10779.9 KDO22583.1 - 0.4 10.9 8.1 9.6 6.5 0.3 3.2 2 1 1 3 3 3 0 Haemolysin XhlA Fib_alpha PF08702.10 KDO22583.1 - 0.41 10.8 9.3 0.17 12.1 4.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 KDO22583.1 - 0.42 8.7 11.5 0.24 9.5 3.2 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Nsp1_C PF05064.13 KDO22583.1 - 0.45 10.3 5.2 6.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region BLOC1_2 PF10046.9 KDO22583.1 - 0.9 9.9 11.8 8.5 6.8 0.4 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 KDO22583.1 - 1 9.4 6.9 1.4 9.1 6.0 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.11 KDO22583.1 - 1.3 9.7 7.9 14 6.3 7.7 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF16 PF01519.16 KDO22583.1 - 1.9 9.1 11.1 11 6.5 6.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2203 PF09969.9 KDO22583.1 - 2 9.2 9.3 68 4.2 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TEX13 PF15186.6 KDO22583.1 - 2.8 7.6 8.3 3.8 7.2 3.9 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF2205 PF10224.9 KDO22583.1 - 4.6 7.3 9.1 0.61 10.1 2.0 2.8 1 1 2 3 3 3 0 Short coiled-coil protein Snapin_Pallidin PF14712.6 KDO22583.1 - 4.9 7.7 11.1 6.9 7.2 3.7 3.0 1 1 2 3 3 3 0 Snapin/Pallidin Occludin_ELL PF07303.13 KDO22583.1 - 5.5 7.8 8.4 33 5.3 0.5 3.0 2 1 0 2 2 2 0 Occludin homology domain TMPIT PF07851.13 KDO22583.1 - 7.7 5.7 10.3 4.6 6.4 2.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein VPS9 PF02204.18 KDO22584.1 - 7e-15 55.1 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-RING_2 PF13639.6 KDO22585.1 - 8.2e-10 38.9 3.3 2e-09 37.6 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO22585.1 - 3e-09 37.0 1.4 5.6e-09 36.2 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO22585.1 - 9.9e-08 31.7 5.0 2.1e-07 30.6 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22585.1 - 1.3e-06 28.3 0.0 2.6e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 PX domain zf-C3HC4 PF00097.25 KDO22585.1 - 2e-06 27.6 1.1 4e-06 26.6 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22585.1 - 2.9e-05 24.0 1.3 7.3e-05 22.7 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO22585.1 - 7.1e-05 22.5 1.2 0.00018 21.2 1.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO22585.1 - 0.00022 21.1 1.2 0.00043 20.2 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO22585.1 - 0.00041 20.1 3.3 0.0007 19.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO22585.1 - 0.00059 19.8 0.6 0.00099 19.1 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KDO22585.1 - 0.0007 19.7 3.7 0.0015 18.6 3.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KDO22585.1 - 0.0012 18.4 2.6 0.0026 17.4 2.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO22585.1 - 0.014 15.2 5.9 0.025 14.4 5.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PI3_PI4_kinase PF00454.27 KDO22586.1 - 2.6e-41 142.1 0.0 5.5e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 KDO22586.1 - 5.2e-23 81.6 0.0 6.7e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 NUC194 domain FATC PF02260.20 KDO22586.1 - 4.3e-09 36.0 0.0 1.2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KDO22586.1 - 7 7.1 23.5 0.73 10.3 0.2 7.5 7 1 1 8 8 8 0 HEAT repeats zf-RING_2 PF13639.6 KDO22587.1 - 8.8e-13 48.4 7.6 2.4e-12 47.0 7.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO22587.1 - 1.4e-09 38.1 6.1 3.4e-09 36.8 6.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO22587.1 - 1.3e-07 31.5 4.7 1.3e-07 31.5 4.7 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO22587.1 - 2e-07 30.8 7.8 2e-07 30.8 7.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22587.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 KDO22587.1 - 1e-06 28.3 6.4 3.8e-06 26.5 6.4 2.0 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO22587.1 - 1.2e-06 28.2 10.3 7.8e-06 25.6 10.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22587.1 - 7.9e-06 25.7 4.9 1.5e-05 24.9 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO22587.1 - 1.6e-05 24.7 7.2 2.7e-05 23.9 6.2 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO22587.1 - 4.6e-05 23.2 7.5 5.9e-05 22.8 6.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO22587.1 - 5.4e-05 23.2 1.9 0.00012 22.1 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KDO22587.1 - 0.00017 21.7 3.6 0.0006 19.9 3.6 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KDO22587.1 - 0.0039 17.3 4.9 0.01 16.0 4.9 1.7 1 1 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 KDO22587.1 - 0.029 14.0 7.2 0.098 12.3 7.2 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type YdaT_toxin PF06254.11 KDO22587.1 - 0.072 13.7 0.2 0.18 12.4 0.2 1.7 1 0 0 1 1 1 0 Putative bacterial toxin ydaT Zeta_toxin PF06414.12 KDO22587.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin zf-RING_4 PF14570.6 KDO22587.1 - 0.53 10.1 4.6 1.6 8.6 4.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KDO22588.1 - 2.1e-11 44.0 7.4 3.5e-10 40.0 1.3 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KDO22588.1 - 4.1e-09 36.1 0.8 4.1e-09 36.1 0.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22588.1 - 8.7e-09 35.4 0.0 2.7e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 PX domain zf-rbx1 PF12678.7 KDO22588.1 - 6.4e-08 32.8 6.9 1.5e-07 31.6 6.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO22588.1 - 1.1e-07 31.6 3.8 2.3e-07 30.6 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO22588.1 - 2.3e-06 27.2 3.9 8.9e-05 22.2 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO22588.1 - 2.9e-05 24.0 2.6 3.6e-05 23.7 1.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO22588.1 - 5.5e-05 23.0 5.4 0.00021 21.2 5.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO22588.1 - 8.4e-05 22.4 0.4 8.4e-05 22.4 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO22588.1 - 0.00022 21.0 0.4 0.00022 21.0 0.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO22588.1 - 0.0014 18.7 3.4 0.003 17.6 3.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KDO22588.1 - 0.01 16.1 2.4 0.022 15.0 2.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family RINGv PF12906.7 KDO22588.1 - 0.16 12.1 5.5 0.12 12.6 1.1 2.4 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 KDO22588.1 - 0.16 12.1 6.0 0.26 11.5 1.7 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO22588.1 - 0.86 9.4 6.8 0.43 10.4 1.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KDO22588.1 - 1.2 8.8 9.4 0.036 13.7 2.9 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KDO22589.1 - 5e-13 49.2 8.1 5e-13 49.2 8.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KDO22589.1 - 2.1e-08 34.3 9.6 9.9e-08 32.2 9.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO22589.1 - 3.3e-08 33.4 4.8 9.3e-08 32.0 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO22589.1 - 3.6e-08 33.1 9.5 4.4e-08 32.9 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO22589.1 - 4.5e-07 29.6 9.4 4.5e-07 29.6 9.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22589.1 - 1.9e-06 27.8 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 KDO22589.1 - 5.4e-06 26.3 8.7 1.4e-05 25.0 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KDO22589.1 - 5.5e-06 26.0 4.5 1.5e-05 24.7 4.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KDO22589.1 - 3e-05 24.0 7.4 0.00011 22.2 7.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KDO22589.1 - 0.0012 18.9 7.4 0.0012 18.9 7.4 2.1 2 1 0 2 2 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KDO22589.1 - 0.0021 17.9 11.7 0.0061 16.4 10.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KDO22589.1 - 0.0022 18.1 5.4 0.0079 16.3 5.4 2.0 1 1 0 1 1 1 1 RING-variant domain Prok-RING_1 PF14446.6 KDO22589.1 - 0.015 15.3 3.2 0.015 15.3 3.2 2.4 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 KDO22589.1 - 0.037 13.8 4.9 0.092 12.6 4.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KDO22589.1 - 0.042 13.5 8.5 0.11 12.2 8.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO22589.1 - 0.063 13.2 13.7 0.093 12.6 6.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KDO22589.1 - 0.38 10.6 10.5 0.77 9.6 10.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KDO22589.1 - 1.6 9.0 11.1 19 5.5 9.6 2.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KDO22589.1 - 6.5 6.7 11.2 20 5.2 11.2 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KDO22590.1 - 5.2e-13 49.1 8.2 5.2e-13 49.1 8.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO22590.1 - 1.4e-08 34.3 6.4 3.8e-08 32.9 6.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO22590.1 - 1.6e-08 34.3 8.1 1.6e-08 34.3 8.1 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO22590.1 - 1.1e-07 31.5 7.9 3.6e-07 29.9 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22590.1 - 1.2e-07 31.9 10.2 1.2e-07 31.9 10.2 2.6 2 2 0 2 2 2 1 RING-H2 zinc finger domain PX PF00787.24 KDO22590.1 - 2.5e-07 30.7 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 KDO22590.1 - 4.6e-07 29.7 5.6 9.4e-07 28.7 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO22590.1 - 1.9e-06 27.8 5.0 6.7e-06 26.0 5.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO22590.1 - 8.4e-06 25.6 3.6 1.8e-05 24.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO22590.1 - 3.9e-05 23.6 4.8 3.9e-05 23.6 4.8 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO22590.1 - 0.0008 19.0 7.0 0.0025 17.4 7.0 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO22590.1 - 0.014 15.2 3.4 0.16 11.8 2.8 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KDO22590.1 - 0.017 15.3 7.7 0.076 13.2 7.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KDO22590.1 - 0.032 14.0 4.6 0.072 12.9 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KDO22590.1 - 0.038 14.1 7.9 0.11 12.6 7.9 1.9 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KDO22590.1 - 0.045 13.9 4.2 0.14 12.3 4.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KDO22590.1 - 0.053 13.4 6.4 0.22 11.4 6.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 KDO22590.1 - 0.091 12.9 3.8 0.25 11.5 3.8 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KDO22590.1 - 0.68 9.9 8.5 1 9.3 7.2 2.0 1 1 1 2 2 2 0 PHD-finger zf-C3H2C3 PF17122.5 KDO22590.1 - 3 7.9 9.5 1 9.5 5.9 2.2 2 0 0 2 2 1 0 Zinc-finger zf-RING-like PF08746.11 KDO22590.1 - 4.4 7.7 9.5 1.7 9.0 6.4 2.0 2 0 0 2 2 1 0 RING-like domain PX PF00787.24 KDO22591.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-RING_2 PF13639.6 KDO22591.1 - 0.016 15.6 10.2 0.04 14.3 10.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 KDO22591.1 - 0.32 10.8 6.2 0.78 9.5 6.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KDO22591.1 - 0.35 10.9 8.3 0.66 10.0 8.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KDO22592.1 - 2.7e-13 50.0 3.3 1.1e-10 41.7 1.2 2.7 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 KDO22592.1 - 1.4e-10 41.2 5.4 7.9e-09 35.7 5.4 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO22592.1 - 4e-09 36.1 0.5 5.5e-05 22.8 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger PX PF00787.24 KDO22592.1 - 5.6e-09 36.0 0.0 9.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 KDO22592.1 - 2.7e-08 33.5 6.1 5.2e-08 32.6 1.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO22592.1 - 9.1e-06 25.6 2.9 1.1e-05 25.4 0.7 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO22592.1 - 2.4e-05 24.2 4.3 4.9e-05 23.2 0.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO22592.1 - 3.1e-05 23.9 1.9 0.0003 20.8 1.4 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO22592.1 - 3.2e-05 23.7 0.5 3.2e-05 23.7 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO22592.1 - 0.0001 22.1 8.7 0.00067 19.5 7.5 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO22592.1 - 0.00044 20.1 0.5 0.00044 20.1 0.5 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KDO22592.1 - 0.013 15.6 1.9 0.013 15.6 1.9 2.4 2 1 1 3 3 3 0 RING-variant domain zf-Nse PF11789.8 KDO22592.1 - 0.14 12.0 2.1 0.36 10.7 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KDO22592.1 - 0.48 10.1 6.9 0.053 13.2 1.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KDO22593.1 - 2.8e-13 50.0 9.9 5.6e-13 49.0 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO22593.1 - 2.3e-09 37.0 12.3 2.5e-09 36.8 10.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22593.1 - 4.7e-08 33.2 12.7 9.9e-08 32.2 12.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO22593.1 - 2.5e-07 30.3 7.6 4.8e-07 29.4 7.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO22593.1 - 2.7e-07 30.3 10.2 5.6e-07 29.3 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22593.1 - 4.3e-07 29.9 0.0 9.1e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 PX domain zf-RING_UBOX PF13445.6 KDO22593.1 - 1.9e-06 27.8 6.4 3.7e-06 26.8 6.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO22593.1 - 2.8e-05 24.0 9.0 5.3e-05 23.1 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO22593.1 - 0.0001 22.1 6.1 0.00022 21.0 6.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO22593.1 - 0.00017 21.5 9.6 0.0012 18.8 9.6 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO22593.1 - 0.00071 19.4 11.5 0.0014 18.5 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO22593.1 - 0.26 10.9 14.3 0.54 9.9 14.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO22593.1 - 0.52 10.2 8.0 1.3 8.9 8.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 KDO22593.1 - 1.3 9.2 15.6 0.079 13.1 10.1 1.9 2 0 0 2 2 2 0 RING-variant domain zf-RING_2 PF13639.6 KDO22594.1 - 2.6e-11 43.7 9.1 2.6e-11 43.7 9.1 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO22594.1 - 3.2e-09 36.9 9.2 7.8e-09 35.7 9.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO22594.1 - 2.3e-07 30.7 5.3 1e-06 28.7 5.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KDO22594.1 - 3.2e-07 30.1 9.7 6.3e-07 29.2 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22594.1 - 5.4e-07 29.6 0.0 9.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 KDO22594.1 - 6.2e-06 25.9 12.8 2.9e-05 23.8 12.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO22594.1 - 9.3e-06 25.3 7.7 9.3e-06 25.3 7.7 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO22594.1 - 2.6e-05 24.1 8.1 5.7e-05 23.0 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_16 PF17034.5 KDO22594.1 - 0.00018 21.7 1.8 0.0004 20.6 1.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family zf-C3HC4_3 PF13920.6 KDO22594.1 - 0.00081 19.2 8.0 0.0023 17.8 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22594.1 - 0.0013 18.8 3.0 0.0013 18.8 3.0 2.8 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO22594.1 - 0.016 15.0 10.0 0.11 12.4 10.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KDO22594.1 - 0.034 14.3 7.9 0.17 12.1 7.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Herpes_gp2 PF05955.11 KDO22594.1 - 0.18 11.3 1.9 0.37 10.3 1.9 1.5 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 RINGv PF12906.7 KDO22594.1 - 0.61 10.3 8.0 2.1 8.5 8.0 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 KDO22595.1 - 2.3e-10 40.6 5.9 6.9e-10 39.1 5.9 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO22595.1 - 1.5e-09 38.0 3.3 2.5e-09 37.3 3.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO22595.1 - 2.4e-08 33.7 1.5 4.3e-08 32.9 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22595.1 - 1.1e-06 28.5 1.4 2.1e-06 27.6 1.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO22595.1 - 1.8e-06 27.7 8.4 3e-05 23.8 8.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22595.1 - 0.00015 21.6 0.7 0.00034 20.5 0.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KDO22595.1 - 0.00018 21.2 0.2 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 KDO22595.1 - 0.0014 18.5 4.7 0.0075 16.1 4.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO22595.1 - 0.0014 18.6 0.1 0.0019 18.2 0.1 1.2 1 0 0 1 1 1 1 PX domain Prok-RING_4 PF14447.6 KDO22595.1 - 0.002 17.9 0.4 0.002 17.9 0.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO22595.1 - 0.0064 16.1 0.4 0.0064 16.1 0.4 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO22595.1 - 0.017 15.2 3.5 0.039 14.0 3.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KDO22595.1 - 0.076 13.2 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING-like PF08746.11 KDO22595.1 - 0.088 13.1 0.5 0.2 12.0 0.5 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 KDO22596.1 - 8.2e-08 32.0 9.9 1.3e-07 31.3 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KDO22596.1 - 1.8e-07 30.9 6.2 7e-07 29.0 6.8 1.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KDO22596.1 - 2.8e-07 30.3 10.4 4.3e-07 29.7 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22596.1 - 3.8e-06 26.8 4.1 3.8e-06 26.8 4.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO22596.1 - 5.8e-06 26.4 9.2 1.1e-05 25.5 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RAWUL PF16207.5 KDO22596.1 - 1.5e-05 25.6 0.2 0.00018 22.1 0.2 2.4 1 1 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 KDO22596.1 - 5.7e-05 23.4 10.0 9.6e-05 22.6 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain DUF3337 PF11816.8 KDO22596.1 - 0.00011 22.2 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) zf-C3HC4_3 PF13920.6 KDO22596.1 - 0.00017 21.4 6.6 0.00031 20.6 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22596.1 - 0.00066 19.6 10.8 0.0017 18.3 11.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KDO22596.1 - 0.0087 15.9 5.0 0.017 14.9 5.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KDO22596.1 - 0.012 15.8 4.5 0.02 15.0 4.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KDO22596.1 - 0.019 15.2 5.4 0.036 14.3 5.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KDO22596.1 - 0.036 13.9 6.8 0.071 13.0 6.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KDO22596.1 - 0.047 13.5 3.3 0.096 12.5 3.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KDO22596.1 - 0.1 12.7 2.1 0.2 11.7 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DnaJ_CXXCXGXG PF00684.19 KDO22596.1 - 0.3 11.5 2.5 0.76 10.2 2.5 1.6 1 0 0 1 1 1 0 DnaJ central domain YdjO PF14169.6 KDO22596.1 - 2.2 8.1 5.7 1.9 8.3 2.0 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO DUF1272 PF06906.11 KDO22596.1 - 2.5 8.2 6.5 6.2 7.0 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) RNase_J_C PF17770.1 KDO22599.1 - 0.021 15.9 0.2 14 6.8 0.0 3.0 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain DUF4366 PF14283.6 KDO22599.1 - 0.043 13.9 0.7 0.084 12.9 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) BLYB PF05289.11 KDO22599.1 - 0.073 13.3 0.5 2 8.6 0.0 2.6 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein zf-UDP PF14569.6 KDO22599.1 - 0.11 12.6 0.2 0.71 10.0 0.0 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger Mg_trans_NIPA PF05653.14 KDO22600.1 - 2.6e-14 53.0 12.1 2.6e-14 53.0 12.1 1.7 2 1 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 KDO22600.1 - 0.01 16.0 32.4 0.072 13.3 11.2 3.4 2 1 0 2 2 2 0 EamA-like transporter family UPF0242 PF06785.11 KDO22600.1 - 0.38 10.8 1.4 0.78 9.8 1.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2101 PF09874.9 KDO22600.1 - 1.7 8.3 7.5 0.19 11.4 1.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) TolA_bind_tri PF16331.5 KDO22601.1 - 0.00033 20.7 1.6 0.00033 20.7 1.6 3.2 1 1 1 2 2 2 1 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 KDO22601.1 - 0.0022 18.0 15.9 0.0093 16.0 1.7 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 KDO22601.1 - 0.0068 16.4 5.5 0.0068 16.4 5.5 2.8 1 1 2 3 3 3 1 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KDO22601.1 - 0.011 15.8 5.2 0.011 15.8 5.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KDO22601.1 - 0.036 14.7 2.1 0.036 14.7 2.1 3.1 1 1 2 3 3 3 0 Initiation control protein YabA Phage_GP20 PF06810.11 KDO22601.1 - 0.056 13.3 8.4 0.19 11.5 7.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1664 PF07889.12 KDO22601.1 - 0.061 13.4 0.4 0.061 13.4 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 KDO22601.1 - 0.068 11.8 2.8 1.3 7.5 0.0 2.1 1 1 0 2 2 2 0 Flagellar Assembly Protein A Tup_N PF08581.10 KDO22601.1 - 0.21 11.9 10.9 0.12 12.7 2.5 2.7 1 1 1 2 2 2 0 Tup N-terminal Filament PF00038.21 KDO22601.1 - 0.24 10.9 19.5 0.2 11.2 2.2 3.0 2 1 1 3 3 3 0 Intermediate filament protein DUF724 PF05266.14 KDO22601.1 - 0.32 10.8 15.6 0.76 9.6 4.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 KDO22601.1 - 0.38 11.7 16.1 3.3 8.7 9.1 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Med14 PF08638.11 KDO22601.1 - 0.39 10.1 5.2 2.1 7.7 1.7 2.4 2 1 0 2 2 2 0 Mediator complex subunit MED14 NYD-SP28_assoc PF14775.6 KDO22601.1 - 0.48 10.6 4.6 1.7 8.8 0.4 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain FliD_N PF02465.18 KDO22601.1 - 0.49 11.1 4.6 0.33 11.7 0.7 2.5 2 1 1 3 3 2 0 Flagellar hook-associated protein 2 N-terminus JIP_LZII PF16471.5 KDO22601.1 - 0.58 10.4 5.1 1.2 9.3 0.4 3.2 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 KDO22601.1 - 0.87 9.4 8.9 0.064 13.0 1.8 2.8 2 2 2 4 4 4 0 Septum formation initiator Tropomyosin_1 PF12718.7 KDO22601.1 - 1.1 9.4 15.7 0.31 11.2 5.4 2.8 1 1 2 3 3 3 0 Tropomyosin like GAS PF13851.6 KDO22601.1 - 1.2 8.4 18.9 0.63 9.3 12.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KDO22601.1 - 1.3 9.2 15.4 1.4 9.2 3.7 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 KDO22601.1 - 1.7 9.2 4.8 3.9 8.0 1.6 2.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 KDO22601.1 - 1.8 7.6 10.3 1.5 7.8 8.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 KDO22601.1 - 2.4 8.6 20.3 1.7 9.1 10.5 2.8 2 1 0 3 3 2 0 Centromere protein H (CENP-H) GIT_CC PF16559.5 KDO22601.1 - 5.4 7.0 10.7 0.53 10.2 1.2 3.4 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor COG2 PF06148.11 KDO22601.1 - 5.7 7.0 8.7 7.2 6.7 3.7 2.7 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 KDO22601.1 - 6.9 7.2 16.8 25 5.4 11.0 3.4 2 1 0 2 2 2 0 Cell division protein ZapB KxDL PF10241.9 KDO22601.1 - 7.1 7.0 13.9 0.64 10.3 1.1 3.9 2 1 1 4 4 4 0 Uncharacterized conserved protein Fez1 PF06818.15 KDO22601.1 - 7.2 7.0 18.0 6.5 7.2 11.6 2.2 1 1 0 2 2 2 0 Fez1 DUF4407 PF14362.6 KDO22601.1 - 8.3 5.7 17.6 27 4.0 17.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BST2 PF16716.5 KDO22601.1 - 8.5 7.0 14.0 0.36 11.4 3.4 3.1 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 LPP PF04728.13 KDO22601.1 - 9.5 6.7 16.3 0.85 10.1 2.8 4.4 4 1 1 5 5 4 0 Lipoprotein leucine-zipper Pox_VP8_L4R PF04498.12 KDO22602.1 - 0.069 12.7 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R MFS_1 PF07690.16 KDO22603.1 - 1.2e-30 106.6 56.1 5.3e-25 88.1 34.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_10 PF13374.6 KDO22604.1 - 1.7e-64 212.1 17.6 2.1e-08 33.8 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22604.1 - 6.7e-57 189.7 23.9 7e-14 51.9 0.7 7.9 4 1 4 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22604.1 - 3.3e-16 58.0 6.2 0.58 10.3 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22604.1 - 1.9e-10 40.1 11.4 0.016 15.4 0.1 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KDO22604.1 - 3e-09 36.6 9.5 1.9 9.3 0.2 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22604.1 - 1.3e-08 34.2 20.0 0.68 9.9 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22604.1 - 3.3e-08 33.0 18.9 1.4 9.2 0.3 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22604.1 - 3.5e-07 30.5 27.8 0.025 15.4 0.4 9.0 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO22604.1 - 1.8e-06 27.6 17.2 0.0086 15.5 1.3 3.6 1 1 3 4 4 4 3 MalT-like TPR region TPR_3 PF07720.12 KDO22604.1 - 0.00012 22.0 6.2 2 8.5 0.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO22604.1 - 0.0011 19.2 9.8 12 6.5 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat FIST_C PF10442.9 KDO22604.1 - 0.0068 16.4 1.4 0.19 11.7 0.0 3.5 3 1 1 4 4 4 1 FIST C domain TPR_19 PF14559.6 KDO22604.1 - 0.013 16.0 23.8 0.18 12.4 3.4 6.3 5 3 2 7 7 7 0 Tetratricopeptide repeat RPN6_N PF18055.1 KDO22604.1 - 0.025 14.9 1.0 51 4.3 0.0 3.8 3 1 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_16 PF13432.6 KDO22604.1 - 0.096 13.4 24.5 7.3 7.3 0.1 8.1 6 3 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO22604.1 - 1.9 9.3 15.8 44 5.0 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MFS_1 PF07690.16 KDO22605.1 - 4.6e-21 75.1 43.0 4.1e-14 52.3 28.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.11 KDO22605.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1616) DUF3687 PF12459.8 KDO22605.1 - 6.1 6.4 6.9 3.7 7.1 1.2 2.6 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein MFS_1 PF07690.16 KDO22606.1 - 1.9e-23 83.0 32.1 1.9e-23 83.0 32.1 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF4112 PF13430.6 KDO22606.1 - 0.059 13.6 0.1 0.059 13.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4112) DUF3687 PF12459.8 KDO22606.1 - 5.8 6.5 6.9 4 7.0 1.2 2.8 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein MFS_1 PF07690.16 KDO22607.1 - 6.9e-29 100.9 51.3 2e-22 79.6 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1218 PF06749.12 KDO22607.1 - 0.0042 17.6 0.0 0.0042 17.6 0.0 3.6 5 2 0 5 5 5 1 Protein of unknown function (DUF1218) DUF1180 PF06679.12 KDO22608.1 - 0.075 13.4 0.1 0.082 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-CXXC PF02008.20 KDO22608.1 - 4.6 7.3 19.2 5.1 7.2 3.0 2.7 2 0 0 2 2 2 0 CXXC zinc finger domain Nucleoporin_FG PF13634.6 KDO22609.1 - 1.3 9.9 15.9 3.1 8.7 0.4 3.7 2 1 0 3 3 3 0 Nucleoporin FG repeat region Ins145_P3_rec PF08709.11 KDO22610.1 - 2.2e-29 102.2 0.0 1.6e-28 99.4 0.0 2.3 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 KDO22610.1 - 8.6e-13 48.5 0.6 2.6e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 MIR domain RYDR_ITPR PF01365.21 KDO22610.1 - 2.4e-11 43.4 0.4 2.4e-11 43.4 0.4 4.6 5 1 1 6 6 6 1 RIH domain RIH_assoc PF08454.11 KDO22610.1 - 8.4e-11 41.6 1.0 8.4e-11 41.6 1.0 2.7 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ion_trans PF00520.31 KDO22610.1 - 0.0026 17.0 17.3 0.045 13.0 10.8 3.2 2 1 0 2 2 2 1 Ion transport protein HAD_2 PF13419.6 KDO22610.1 - 0.012 15.7 0.0 0.046 13.8 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Deltaretro_Tax PF05599.11 KDO22610.1 - 0.029 14.9 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Rieske PF00355.26 KDO22610.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Syntaxin-6_N PF09177.11 KDO22610.1 - 1.6 9.3 5.3 2.7 8.6 0.0 3.7 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Ins145_P3_rec PF08709.11 KDO22611.1 - 1.9e-26 92.6 0.1 1.9e-25 89.3 0.0 2.7 2 1 1 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 KDO22611.1 - 2.9e-11 43.1 0.4 2.3e-10 40.2 0.2 2.7 2 0 0 2 2 2 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 KDO22611.1 - 1.6e-08 34.2 0.2 2.9e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 RIH domain MIR PF02815.19 KDO22611.1 - 1.2e-07 31.8 0.1 3.9e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 MIR domain Ion_trans PF00520.31 KDO22611.1 - 1.8e-05 24.1 15.3 1.8e-05 24.1 15.3 2.0 2 0 0 2 2 2 1 Ion transport protein Beach PF02138.18 KDO22612.1 - 4.3e-104 347.8 0.0 6.7e-104 347.1 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KDO22612.1 - 1.5e-13 50.6 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KDO22612.1 - 0.00016 22.4 5.9 0.17 12.8 0.1 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DDE_Tnp_1_5 PF13737.6 KDO22613.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Dynein_light PF01221.18 KDO22615.1 - 2.1e-43 146.6 1.8 2.3e-43 146.4 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 adh_short PF00106.25 KDO22616.1 - 1.3e-46 158.5 0.3 1.8e-46 158.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO22616.1 - 8.8e-31 107.3 0.1 1.1e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO22616.1 - 2.1e-09 37.5 2.4 5.6e-09 36.2 2.4 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KDO22616.1 - 0.018 14.3 0.2 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiA PF01656.23 KDO22616.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Epimerase PF01370.21 KDO22616.1 - 0.14 11.6 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5476 PF17570.2 KDO22617.1 - 0.0021 18.4 0.4 0.013 15.8 0.4 2.5 1 0 0 1 1 1 1 Family of unknown function (DUF5476) Methyltr_RsmB-F PF01189.17 KDO22618.1 - 7.5e-73 244.5 0.0 1.5e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KDO22618.1 - 6.4e-08 33.0 0.0 1.9e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 KDO22618.1 - 2.8e-05 24.0 0.0 6.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KDO22618.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KDO22618.1 - 0.00023 21.8 0.4 0.00073 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KDO22618.1 - 0.00096 19.0 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KDO22618.1 - 0.0022 17.4 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PQQ_3 PF13570.6 KDO22619.1 - 0.00082 19.8 0.1 0.00082 19.8 0.1 7.5 9 3 1 10 10 10 1 PQQ-like domain Baculo_p74_N PF08404.10 KDO22619.1 - 0.04 13.0 0.1 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Baculoviridae P74 N-terminal Trypan_PARP PF05887.11 KDO22619.1 - 0.54 10.2 16.2 1.1 9.2 16.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PALP PF00291.25 KDO22620.1 - 3.1e-77 259.9 2.0 3.9e-77 259.6 2.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 KDO22620.1 - 0.00035 20.3 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain Ribosomal_L28e PF01778.17 KDO22621.1 - 2.8e-38 131.2 1.7 2.8e-38 131.2 1.7 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KDO22621.1 - 2.2e-30 105.2 16.5 2.2e-30 105.2 16.5 2.8 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KDO22621.1 - 5.9e-05 22.6 21.1 7.5e-05 22.2 21.1 1.1 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.12 KDO22621.1 - 0.00076 19.3 21.4 0.0011 18.8 21.4 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KDO22621.1 - 0.034 12.4 29.6 0.049 11.9 29.6 1.2 1 0 0 1 1 1 0 Nop14-like family Exonuc_VII_L PF02601.15 KDO22621.1 - 0.37 10.3 3.0 0.44 10.1 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1151 PF06625.11 KDO22621.1 - 8.5 6.4 14.8 37 4.3 14.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) Ribosomal_S11 PF00411.19 KDO22622.1 - 5.5e-46 155.5 2.3 7.1e-46 155.1 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 KDO22622.1 - 0.072 12.1 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) EGF_2 PF07974.13 KDO22623.1 - 0.00031 21.0 16.8 0.00031 21.0 16.8 7.1 7 0 0 7 7 7 3 EGF-like domain EGF PF00008.27 KDO22623.1 - 0.00045 20.5 6.9 0.00045 20.5 6.9 6.3 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 KDO22623.1 - 0.00073 20.1 2.2 0.00073 20.1 2.2 7.2 8 1 0 8 8 8 3 Human growth factor-like EGF EGF_Tenascin PF18720.1 KDO22623.1 - 0.038 14.1 9.7 0.038 14.1 9.7 5.4 5 0 0 5 5 5 0 Tenascin EGF domain NHL PF01436.21 KDO22624.1 - 8.8e-28 94.9 5.9 2.2e-07 30.5 0.0 5.8 6 0 0 6 6 6 5 NHL repeat SGL PF08450.12 KDO22624.1 - 3.3e-08 33.4 0.0 0.0087 15.7 0.0 3.4 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 KDO22624.1 - 0.00086 19.3 0.0 0.58 10.2 0.0 4.0 5 0 0 5 5 5 1 Beta-propeller repeat Phytase-like PF13449.6 KDO22624.1 - 0.014 15.4 0.0 3.1 7.6 0.0 2.7 1 1 2 3 3 3 0 Esterase-like activity of phytase PQQ_2 PF13360.6 KDO22624.1 - 0.028 14.0 1.6 0.12 11.9 0.1 2.4 1 1 0 2 2 2 0 PQQ-like domain SdiA-regulated PF06977.11 KDO22624.1 - 0.067 12.4 0.0 8.2 5.6 0.0 2.8 3 0 0 3 3 3 0 SdiA-regulated DUF5074 PF16819.5 KDO22624.1 - 0.16 12.1 0.0 15 5.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5074) LRR_8 PF13855.6 KDO22625.1 - 7.4e-10 38.4 0.0 1.5e-05 24.6 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO22625.1 - 1.4e-05 25.3 0.0 0.22 12.0 0.3 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO22625.1 - 0.0022 18.4 13.2 0.0063 16.9 13.2 1.9 1 0 0 1 1 1 1 LNR domain TPR_12 PF13424.6 KDO22626.1 - 8.4e-17 61.2 15.1 5.5e-05 23.4 0.0 5.5 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22626.1 - 6.3e-08 32.1 4.0 0.0014 18.6 0.8 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22626.1 - 0.00013 21.7 9.5 0.03 14.2 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22626.1 - 0.00019 21.3 0.1 0.021 14.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22626.1 - 0.0035 17.1 0.4 0.034 14.0 0.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF410 PF04190.13 KDO22626.1 - 0.025 14.4 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF410) TPR_14 PF13428.6 KDO22626.1 - 0.25 12.3 13.1 3.9 8.6 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22627.1 - 7.8e-17 61.3 2.5 0.00094 19.4 0.1 5.6 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22627.1 - 5.3e-13 48.4 6.0 0.0028 17.5 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22627.1 - 6.5e-05 22.7 0.1 0.028 14.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22627.1 - 0.00031 21.3 1.4 0.27 12.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-RVT PF13966.6 KDO22627.1 - 0.00061 20.4 2.0 0.00067 20.3 0.1 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase TPR_1 PF00515.28 KDO22627.1 - 0.00079 19.1 0.0 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO22627.1 - 0.0068 15.8 0.4 0.014 14.8 0.4 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 KDO22627.1 - 0.026 14.5 0.0 0.41 10.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22627.1 - 0.096 12.9 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO22627.1 - 1.5 9.7 6.2 37 5.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22628.1 - 2.5e-20 72.6 5.7 2.5e-05 24.5 0.0 4.9 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22628.1 - 3.9e-16 58.3 8.3 6.1e-05 22.8 0.9 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22628.1 - 1e-05 25.2 5.0 0.0065 16.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22628.1 - 3.6e-05 23.4 2.1 0.0011 18.7 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22628.1 - 0.00052 20.6 7.2 0.31 12.0 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22628.1 - 0.001 18.9 3.3 0.059 13.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22628.1 - 0.0021 18.1 0.6 0.18 12.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO22628.1 - 0.012 15.8 0.1 0.3 11.3 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KDO22628.1 - 0.029 15.0 1.5 11 6.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO22628.1 - 0.029 15.0 0.3 41 5.2 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO22628.1 - 0.058 13.9 1.6 1.7 9.2 0.4 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO22629.1 - 3e-16 59.5 10.9 0.00034 20.8 0.1 4.8 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22629.1 - 2.4e-08 33.6 6.1 0.00088 19.1 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22629.1 - 2.1e-05 24.3 1.1 0.74 10.1 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22629.1 - 5.8e-05 22.8 0.1 1.6 9.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22629.1 - 0.054 13.7 0.0 8.6 6.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO22629.1 - 0.24 12.1 0.0 0.24 12.1 0.0 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 KDO22629.1 - 0.49 10.1 7.0 1.1 8.9 7.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4381 PF14316.6 KDO22629.1 - 2.1 8.6 6.3 16 5.7 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TPR_14 PF13428.6 KDO22629.1 - 2.5 9.1 18.9 1.1 10.3 0.1 6.7 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO22629.1 - 5.1 7.7 5.9 2.6 8.6 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KDO22630.1 - 3.1e-64 213.6 21.0 8.3e-19 68.0 0.1 6.4 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22630.1 - 4.5e-57 189.7 27.9 4.1e-15 55.9 0.3 9.7 3 2 10 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22630.1 - 4e-48 155.8 9.7 9e-07 28.7 0.0 13.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KDO22630.1 - 7.3e-44 147.3 24.7 9e-12 45.0 0.0 10.8 4 4 8 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 KDO22630.1 - 1.4e-42 142.3 28.4 3.3e-07 30.4 0.4 11.8 12 0 0 12 12 12 9 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO22630.1 - 1.1e-32 113.3 0.0 1.8e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22630.1 - 1.4e-31 109.8 0.0 2.8e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L34e PF01199.18 KDO22630.1 - 0.18 12.1 2.2 0.51 10.7 0.5 2.3 1 1 1 2 2 2 0 Ribosomal protein L34e DZR PF12773.7 KDO22630.1 - 7.4 6.7 14.5 1.6 8.8 10.0 2.3 2 1 0 2 2 2 0 Double zinc ribbon Alpha_kinase PF02816.18 KDO22631.1 - 4e-43 147.7 0.0 6.1e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KDO22631.1 - 0.0068 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain OST-HTH PF12872.7 KDO22631.1 - 0.033 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Alpha_kinase PF02816.18 KDO22632.1 - 1.9e-45 155.2 0.1 2.8e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KDO22632.1 - 1.1e-06 29.2 0.0 2.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KDO22632.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-trcl PF13451.6 KDO22632.1 - 0.47 10.4 5.5 0.073 13.0 0.5 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain Prok-RING_1 PF14446.6 KDO22632.1 - 1.1 9.2 4.5 1.2 9.1 0.3 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Stc1 PF12898.7 KDO22632.1 - 2.5 8.7 7.5 0.28 11.8 1.2 2.4 1 1 1 2 2 2 0 Stc1 domain Ank_2 PF12796.7 KDO22633.1 - 1.4e-27 96.0 13.3 1.6e-10 41.4 0.3 5.1 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22633.1 - 6e-23 80.9 5.8 0.00019 21.9 0.1 5.6 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO22633.1 - 2.6e-19 69.5 0.0 6.1e-10 38.8 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO22633.1 - 2.7e-17 63.0 0.0 1.1e-07 31.4 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Ank_3 PF13606.6 KDO22633.1 - 7.7e-17 59.7 4.0 0.0084 16.5 0.0 8.9 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 KDO22633.1 - 2.4e-14 53.0 14.8 0.0061 17.0 0.1 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KDO22633.1 - 1.4e-13 50.7 14.5 0.00023 21.4 0.1 6.5 5 1 2 7 7 7 3 Ankyrin repeats (many copies) FimA PF16970.5 KDO22633.1 - 0.038 14.2 0.4 0.1 12.8 0.4 1.7 1 0 0 1 1 1 0 Type-1 fimbrial protein, A Pkinase_Tyr PF07714.17 KDO22634.1 - 1.7e-31 109.4 0.0 2.6e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22634.1 - 4.1e-31 108.3 0.0 7.1e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 KDO22634.1 - 2.1e-20 72.5 9.0 6.2e-10 39.1 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22634.1 - 2.5e-16 60.0 3.7 3.9e-11 43.4 0.4 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22634.1 - 4e-16 59.2 2.5 6e-08 33.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO22634.1 - 1.2e-14 54.0 5.3 6e-07 29.6 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO22634.1 - 3.5e-12 45.4 1.7 9.4e-05 22.5 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat APH PF01636.23 KDO22634.1 - 0.001 19.1 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO22634.1 - 0.005 16.2 0.1 0.0078 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KDO22635.1 - 9.6e-08 31.7 0.1 0.024 14.0 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 KDO22635.1 - 2.3e-06 27.8 0.0 1.9e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KDO22635.1 - 0.0015 17.9 0.1 0.081 12.2 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KDO22637.1 - 3.8e-49 165.2 18.5 1.7e-13 50.9 1.4 7.0 2 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22637.1 - 1.4e-43 146.7 16.2 6.2e-08 33.0 0.3 9.7 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22637.1 - 9.2e-34 111.7 14.1 0.00019 21.6 0.0 12.2 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 KDO22637.1 - 1.4e-32 110.7 32.0 6.7e-05 23.2 0.0 13.4 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.6 KDO22637.1 - 1.4e-32 111.3 20.2 1.2e-06 28.7 0.0 8.6 6 2 2 9 9 9 5 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO22637.1 - 6.9e-25 87.9 0.0 6.5e-22 78.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22637.1 - 2.1e-21 76.4 0.0 1e-17 64.3 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KDO22637.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 KDO22637.1 - 0.19 11.8 8.9 0.45 10.6 8.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 KDO22637.1 - 9.4 5.7 9.1 0.26 10.6 2.5 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pkinase PF00069.25 KDO22638.1 - 5.8e-58 196.3 0.0 3.5e-30 105.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22638.1 - 3.7e-46 157.5 0.0 9e-27 94.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 KDO22638.1 - 1.9e-17 63.6 0.3 9.7e-07 29.3 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22638.1 - 7.6e-13 48.7 0.1 0.00022 21.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22638.1 - 2.7e-12 46.7 1.6 0.0025 18.1 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22638.1 - 1.1e-10 40.7 0.5 0.47 11.2 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KDO22638.1 - 2e-07 31.2 2.5 0.77 10.3 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Kdo PF06293.14 KDO22638.1 - 0.00079 18.8 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO22638.1 - 0.015 14.6 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like FadA PF09403.10 KDO22638.1 - 0.029 14.9 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Nup160 PF11715.8 KDO22639.1 - 9.9e-13 47.6 0.0 4.1e-08 32.3 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Pkinase PF00069.25 KDO22640.1 - 3.9e-35 121.5 0.0 4.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22640.1 - 8.3e-30 103.9 0.0 9.6e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO22640.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO22640.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO22640.1 - 0.19 11.0 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KDO22641.1 - 6.5e-46 156.8 0.0 8.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22641.1 - 2.8e-41 141.5 0.0 3.4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO22641.1 - 0.0018 17.1 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO22641.1 - 0.0025 17.2 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO22641.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO22641.1 - 0.024 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO22641.1 - 0.034 14.1 1.2 0.048 13.6 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family TPR_12 PF13424.6 KDO22643.1 - 6.4e-16 58.4 12.2 7.8e-05 22.9 0.2 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22643.1 - 2.9e-09 36.5 1.2 0.0084 15.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22643.1 - 0.0066 16.5 2.8 2.9 8.2 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22643.1 - 0.024 14.4 0.6 0.59 10.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO22643.1 - 0.038 14.2 0.1 4.1 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 KDO22645.1 - 3.4e-11 42.7 14.4 1.6e-05 24.5 1.4 2.8 1 1 3 4 4 4 3 Leucine rich repeat Notch PF00066.17 KDO22645.1 - 2e-05 24.9 10.7 5.2e-05 23.6 10.7 1.7 1 0 0 1 1 1 1 LNR domain LRR_4 PF12799.7 KDO22645.1 - 0.00033 21.0 7.5 0.0053 17.1 0.7 4.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO22645.1 - 0.19 12.4 2.3 21 6.2 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO22647.1 - 6.6e-15 54.6 2.9 6.8e-08 32.2 0.1 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO22647.1 - 7.1e-10 39.0 2.6 3.5e-05 24.1 0.1 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO22647.1 - 0.00093 18.7 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Notch PF00066.17 KDO22647.1 - 0.0079 16.6 12.0 0.0079 16.6 12.0 1.9 2 0 0 2 2 2 1 LNR domain CwsA PF10814.8 KDO22647.1 - 0.25 11.5 1.3 0.61 10.3 0.2 2.0 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA LRR_8 PF13855.6 KDO22649.1 - 1.2e-13 50.6 12.7 1.6e-06 27.8 0.4 3.1 1 1 3 4 4 4 4 Leucine rich repeat Notch PF00066.17 KDO22649.1 - 4e-05 24.0 13.2 9.8e-05 22.7 13.2 1.7 1 0 0 1 1 1 1 LNR domain LRR_4 PF12799.7 KDO22649.1 - 0.00017 21.9 11.4 0.13 12.7 0.1 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO22649.1 - 0.27 11.9 7.6 43 5.2 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat PT PF04886.12 KDO22651.1 - 2.5e-14 52.5 43.8 0.0032 17.0 32.5 3.6 1 1 1 2 2 2 2 PT repeat Trypan_PARP PF05887.11 KDO22651.1 - 7.1 6.6 42.0 5.8 6.9 33.6 2.4 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) CAP PF00188.26 KDO22652.1 - 1.4e-09 38.8 1.5 2.9e-09 37.8 1.5 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PT PF04886.12 KDO22652.1 - 0.00031 20.2 31.1 0.19 11.3 5.1 3.8 2 1 0 2 2 2 2 PT repeat NOA36 PF06524.12 KDO22652.1 - 0.0066 15.8 10.1 0.0097 15.3 10.1 1.4 1 0 0 1 1 1 1 NOA36 protein CDC45 PF02724.14 KDO22652.1 - 0.11 10.7 5.2 0.14 10.4 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KDO22652.1 - 2 6.6 8.2 2.3 6.3 8.2 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 KDO22652.1 - 6.5 6.8 5.2 11 6.0 5.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 KDO22652.1 - 7.9 5.7 15.0 11 5.3 15.0 1.1 1 0 0 1 1 1 0 BUD22 AA_permease_2 PF13520.6 KDO22653.1 - 7.7e-13 48.0 33.9 1.1e-12 47.5 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO22653.1 - 1.9e-12 46.6 28.4 2.7e-12 46.0 28.4 1.2 1 0 0 1 1 1 1 Amino acid permease UcrQ PF02939.16 KDO22654.1 - 0.097 12.6 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 UcrQ family YfdX PF10938.8 KDO22654.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 YfdX protein Nop PF01798.18 KDO22655.1 - 1.6e-88 296.0 0.1 1.6e-88 296.0 0.1 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KDO22655.1 - 1.2e-21 76.9 1.4 1.2e-21 76.9 1.4 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain G0-G1_switch_2 PF15103.6 KDO22655.1 - 0.8 10.2 8.3 1.6 9.2 7.1 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Kinesin PF00225.23 KDO22656.1 - 1.5e-74 251.0 0.6 1.8e-74 250.7 0.6 1.1 1 0 0 1 1 1 1 Kinesin motor domain SNF2_assoc PF08455.10 KDO22656.1 - 0.00081 18.5 5.5 0.0023 17.0 1.1 2.0 2 0 0 2 2 2 2 Bacterial SNF2 helicase associated Microtub_bd PF16796.5 KDO22656.1 - 0.013 15.5 0.1 0.052 13.5 0.0 2.1 2 1 1 3 3 3 0 Microtubule binding Na_H_Exchanger PF00999.21 KDO22657.1 - 1.3e-49 169.0 28.9 1.6e-49 168.7 28.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DSPn PF14671.6 KDO22658.1 - 6.5e-29 101.2 0.6 1e-28 100.6 0.4 1.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KDO22658.1 - 1.8e-13 50.5 0.0 4.7e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO22658.1 - 6.7e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO22658.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KDO22658.1 - 0.053 13.5 0.1 0.083 12.8 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Ago_PAZ PF18309.1 KDO22661.1 - 0.064 13.9 0.6 1.2 9.9 0.3 2.1 1 1 1 2 2 2 0 Argonaute PAZ domain HhH-GPD PF00730.25 KDO22664.1 - 2.8e-21 76.0 0.0 1.8e-20 73.4 0.0 2.1 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KDO22664.1 - 4.7e-15 55.5 0.0 1.1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KDO22664.1 - 5.8e-09 35.4 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KDO22664.1 - 0.014 15.9 0.0 0.099 13.3 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix domain MSC PF09402.10 KDO22664.1 - 0.15 11.5 0.8 0.24 10.8 0.8 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain EndIII_4Fe-2S PF10576.9 KDO22664.1 - 4.8 7.6 6.5 0.4 11.1 1.6 1.8 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III SR-25 PF10500.9 KDO22665.1 - 0.01 15.5 10.0 0.014 15.0 10.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 KDO22665.1 - 0.011 13.9 1.1 0.012 13.8 1.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PilJ PF13675.6 KDO22665.1 - 0.058 13.4 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4735 PF15882.5 KDO22665.1 - 0.13 11.7 0.9 0.19 11.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) DUF2400 PF09674.10 KDO22665.1 - 0.25 11.3 2.5 0.34 10.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) EF-hand_1 PF00036.32 KDO22666.1 - 1.2e-184 584.6 38.6 2.2e-06 26.8 0.0 34.8 38 0 0 38 38 38 30 EF hand EF-hand_7 PF13499.6 KDO22666.1 - 1.7e-169 550.6 36.8 2.2e-13 50.4 0.3 21.2 17 4 7 24 24 24 22 EF-hand domain pair EF-hand_6 PF13405.6 KDO22666.1 - 7.9e-157 496.1 48.1 5.2e-05 22.9 0.0 35.5 37 0 0 37 37 36 31 EF-hand domain EF-hand_5 PF13202.6 KDO22666.1 - 1.9e-136 438.1 62.4 2.7e-05 23.5 0.7 31.3 31 0 0 31 31 31 29 EF hand EF-hand_8 PF13833.6 KDO22666.1 - 5.8e-76 250.2 75.8 0.00084 19.1 0.1 32.8 27 7 7 34 34 34 24 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO22666.1 - 2.1e-14 53.8 20.2 6 7.2 0.0 19.6 20 3 3 23 23 23 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO22666.1 - 1.4e-12 47.8 19.8 3.5 8.0 0.2 15.4 16 2 1 17 17 15 1 EF-hand domain EF-hand_4 PF12763.7 KDO22666.1 - 1.5e-11 44.2 42.3 0.36 10.8 0.1 20.3 11 10 11 24 24 24 1 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.11 KDO22666.1 - 1.2e-10 41.6 0.0 0.39 10.9 0.0 10.8 13 3 0 13 13 13 1 EF hand FANCM-MHF_bd PF16783.5 KDO22666.1 - 1.1e-06 28.7 0.4 28 4.8 0.0 8.2 10 0 0 10 10 10 0 FANCM to MHF binding domain Dockerin_1 PF00404.18 KDO22666.1 - 1.2e-06 28.6 23.4 30 4.9 0.1 16.8 20 2 2 22 22 21 0 Dockerin type I domain DUF1707 PF08044.11 KDO22666.1 - 1.1e-05 25.4 8.6 18 5.5 0.0 13.0 18 0 0 18 18 17 0 Domain of unknown function (DUF1707) EF-hand_10 PF14788.6 KDO22666.1 - 1.7e-05 24.6 22.2 7.5 6.5 0.0 10.6 12 0 0 12 12 11 2 EF hand TcdB_toxin_midN PF12256.8 KDO22666.1 - 0.29 10.5 1.7 11 5.4 0.0 4.5 6 0 0 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region FYVE PF01363.21 KDO22667.1 - 9.1e-15 54.6 12.1 1.9e-14 53.5 12.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 KDO22667.1 - 0.00022 21.5 0.1 0.00054 20.3 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KDO22667.1 - 0.00058 20.5 0.2 0.0019 18.8 0.2 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KDO22667.1 - 0.0043 17.4 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO22667.1 - 0.1 12.8 10.8 0.041 14.1 7.8 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Ribonuclease_T2 PF00445.18 KDO22668.1 - 0.00023 21.4 0.1 0.00044 20.5 0.1 1.5 1 1 0 1 1 1 1 Ribonuclease T2 family DUF4886 PF16227.5 KDO22668.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Esterase PF00756.20 KDO22670.1 - 1.1e-28 100.5 0.1 1.4e-28 100.2 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KDO22670.1 - 5.9e-05 22.6 0.6 0.00019 21.0 0.2 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO22670.1 - 0.00066 19.0 0.4 0.0011 18.3 0.3 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KDO22670.1 - 0.0013 17.8 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KDO22670.1 - 0.0024 17.6 0.1 0.0035 17.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO22670.1 - 0.012 16.2 0.1 0.016 15.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KDO22670.1 - 0.015 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase OspE PF02471.17 KDO22670.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.5 2 0 0 2 2 2 0 Borrelia outer surface protein E DUF1057 PF06342.12 KDO22670.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) TPR_12 PF13424.6 KDO22671.1 - 0.0053 17.0 0.9 17 5.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22671.1 - 0.072 13.1 1.1 91 3.4 0.0 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Nucleo_P87 PF07267.11 KDO22672.1 - 0.035 13.0 7.0 0.044 12.6 7.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF908 PF06012.12 KDO22672.1 - 2.1 7.6 4.7 2.9 7.2 4.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Thioredoxin_7 PF13899.6 KDO22673.1 - 3.1e-12 46.5 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KDO22673.1 - 4.4e-11 42.8 0.0 7.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KDO22673.1 - 1.4e-10 40.8 0.1 3.2e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 KDO22673.1 - 0.0019 18.0 1.3 0.0043 16.9 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif TAP_C PF03943.13 KDO22673.1 - 0.026 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain OAD_gamma PF04277.13 KDO22673.1 - 0.18 12.4 1.4 0.43 11.2 1.4 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Vps26 PF03643.15 KDO22674.1 - 2e-39 135.3 0.1 2.5e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KDO22674.1 - 5e-05 23.4 0.2 0.00037 20.6 0.2 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SCAPER_N PF16501.5 KDO22675.1 - 4.3e-08 33.1 2.6 5.3e-06 26.4 0.6 3.2 1 1 1 2 2 2 2 S phase cyclin A-associated protein in the endoplasmic reticulum DUF5403 PF17395.2 KDO22675.1 - 1 9.7 4.7 25 5.3 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5403) polyprenyl_synt PF00348.17 KDO22676.1 - 1.6e-91 305.9 0.0 1.9e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DNA_photolyase PF00875.18 KDO22677.1 - 1.6e-20 73.8 0.4 2.7e-20 73.0 0.4 1.3 1 0 0 1 1 1 1 DNA photolyase HA2 PF04408.23 KDO22678.1 - 2.2e-15 56.8 0.9 6e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KDO22678.1 - 3.4e-13 49.9 0.1 7.2e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KDO22678.1 - 2.8e-12 46.8 0.0 6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KDO22678.1 - 2.7e-11 43.6 0.1 5.6e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO22678.1 - 2.4e-05 24.6 0.2 7.1e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.7 KDO22678.1 - 4.6e-05 23.6 0.1 0.00014 22.1 0.1 1.9 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 KDO22678.1 - 0.00092 19.6 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KDO22678.1 - 0.0011 18.4 0.4 0.0026 17.1 0.0 1.7 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 KDO22678.1 - 0.0016 17.5 0.0 0.0034 16.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein dsRBD2 PF17842.1 KDO22678.1 - 0.0051 17.0 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding domain 2 RsgA_GTPase PF03193.16 KDO22678.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Ribosomal_60s PF00428.19 KDO22678.1 - 0.021 15.4 0.8 0.021 15.4 0.8 3.6 3 0 0 3 3 2 0 60s Acidic ribosomal protein Sigma54_activat PF00158.26 KDO22678.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KDO22678.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KDO22678.1 - 0.16 11.5 0.0 0.46 10.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region CAF-1_p150 PF11600.8 KDO22678.1 - 0.23 11.1 2.7 0.42 10.3 2.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Gemin7 PF11095.8 KDO22679.1 - 2e-08 34.0 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) HTH_psq PF05225.16 KDO22680.1 - 5.8e-09 35.6 0.0 8.9e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 KDO22680.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_1 PF00126.27 KDO22680.1 - 0.085 12.8 0.2 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 KDO22680.1 - 0.09 12.9 0.0 21 5.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PAT1 PF09770.9 KDO22680.1 - 0.77 8.0 33.2 1.1 7.5 33.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ASD2 PF08687.11 KDO22680.1 - 8.2 5.9 11.9 19 4.7 11.9 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 zf-RING_2 PF13639.6 KDO22681.1 - 9.1e-10 38.7 13.2 9.1e-10 38.7 13.2 1.7 2 0 0 2 2 1 1 Ring finger domain PA PF02225.22 KDO22681.1 - 5.8e-09 35.9 0.0 9.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_11 PF17123.5 KDO22681.1 - 1.9e-08 33.9 8.9 4.7e-08 32.6 8.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO22681.1 - 7.1e-07 29.0 9.4 1.4e-06 28.1 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO22681.1 - 3.4e-06 26.8 13.2 6.2e-06 26.0 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22681.1 - 6.2e-06 26.4 10.8 4.8e-05 23.6 10.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO22681.1 - 2.7e-05 24.1 8.1 7.4e-05 22.7 8.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KDO22681.1 - 0.00057 19.5 8.0 0.0014 18.2 8.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_5 PF17121.5 KDO22681.1 - 0.0037 17.1 0.8 0.019 14.8 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO22681.1 - 0.0062 16.4 9.7 0.0062 16.4 9.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO22681.1 - 0.0089 16.1 5.2 0.02 14.9 5.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 KDO22681.1 - 0.014 15.4 2.6 0.061 13.4 2.6 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_5 PF14634.6 KDO22681.1 - 0.016 15.2 11.8 0.032 14.2 11.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 KDO22681.1 - 0.072 13.2 7.5 0.17 12.0 7.5 1.7 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 KDO22681.1 - 0.1 12.5 12.2 0.27 11.2 12.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KDO22681.1 - 0.3 10.9 4.4 0.59 10.0 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KDO22681.1 - 1.7 9.0 7.5 4.4 7.7 7.5 1.8 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KDO22681.1 - 7.4 6.5 10.7 17 5.3 10.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LRR_4 PF12799.7 KDO22682.1 - 1.7e-15 56.9 7.8 0.0025 18.2 0.0 5.5 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO22682.1 - 1.9e-11 43.8 0.9 6.7e-10 38.7 0.3 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KDO22682.1 - 3.8e-09 36.2 7.0 0.00014 21.6 0.1 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KDO22682.1 - 8.1e-09 34.9 0.2 0.12 12.5 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 KDO22682.1 - 0.048 14.2 0.1 21 6.2 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat Cpn60_TCP1 PF00118.24 KDO22683.1 - 1.9e-154 514.9 13.7 2.2e-154 514.8 13.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SCAB_CC PF16712.5 KDO22683.1 - 0.036 13.9 1.2 0.068 13.0 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein PIP5K PF01504.18 KDO22684.1 - 6.9e-67 225.5 0.0 2e-66 224.0 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Ax_dynein_light PF10211.9 KDO22685.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 2.3 3 0 0 3 3 3 1 Axonemal dynein light chain RSN1_7TM PF02714.15 KDO22686.1 - 2.8e-26 92.5 17.7 4.6e-26 91.8 17.7 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KDO22686.1 - 1.3e-19 70.4 0.3 7.7e-19 68.0 0.3 2.5 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KDO22686.1 - 0.00018 21.8 0.0 0.046 13.9 0.1 2.6 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter HTH_ABP1_N PF18107.1 KDO22686.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.8 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain DUF3433 PF11915.8 KDO22686.1 - 7.6 7.1 10.9 0.62 10.6 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) RabGAP-TBC PF00566.18 KDO22687.1 - 7.2e-43 146.7 0.0 1.1e-32 113.4 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Jag_N PF14804.6 KDO22687.1 - 0.036 14.4 0.3 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 Jag N-terminus Eapp_C PF10238.9 KDO22688.1 - 7.4e-26 91.0 7.4 4e-22 78.9 4.3 2.2 1 1 1 2 2 2 2 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 KDO22688.1 - 7.9e-05 22.8 1.9 0.00011 22.4 1.9 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 KDO22688.1 - 0.0031 17.2 0.6 0.34 10.7 0.0 2.6 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein CRT-like PF08627.10 KDO22689.1 - 0.0016 17.5 5.1 0.0016 17.5 5.1 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO22690.1 - 5.1e-08 33.2 8.4 5.1e-08 33.2 8.4 3.4 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 KDO22690.1 - 1.1e-06 28.4 7.6 2.3e-06 27.4 7.6 1.5 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KDO22690.1 - 3.1e-06 26.7 5.2 5.7e-06 25.8 5.2 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 KDO22690.1 - 0.064 12.6 10.0 0.11 11.8 10.0 1.4 1 0 0 1 1 1 0 Triose-phosphate Transporter family HSP70 PF00012.20 KDO22692.1 - 1.8e-54 185.0 0.0 8.2e-46 156.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein DUF3046 PF11248.8 KDO22692.1 - 0.042 14.2 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) FGGY_C PF02782.16 KDO22692.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4242 PF14026.6 KDO22693.1 - 0.031 14.4 0.2 0.073 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) IQ_SEC7_PH PF16453.5 KDO22693.1 - 0.069 13.1 0.5 0.92 9.5 0.0 2.1 1 1 1 2 2 2 0 PH domain Peptidase_S8 PF00082.22 KDO22694.1 - 4.5e-28 98.4 0.5 6.5e-28 97.8 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 KDO22694.1 - 2.7e-15 56.8 0.2 3.4e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO22694.1 - 0.00038 21.1 0.9 0.033 14.9 0.1 3.0 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF4777 PF16007.5 KDO22694.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Ricin_B_lectin PF00652.22 KDO22695.1 - 4.2e-27 94.9 11.6 2.5e-13 50.4 1.1 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO22695.1 - 1.3e-10 41.9 11.7 0.00024 21.8 1.8 4.1 2 1 4 6 6 6 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO22695.1 - 0.0095 15.5 1.3 0.027 14.1 0.2 2.1 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain Vps62 PF06101.11 KDO22696.1 - 0.015 13.6 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 Ricin_B_lectin PF00652.22 KDO22697.1 - 2.6e-13 50.3 3.1 4.9e-13 49.4 3.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO22697.1 - 7.8e-07 29.7 9.4 0.00012 22.7 0.5 2.9 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Delta_lysin PF05372.11 KDO22697.1 - 3.6 7.0 5.0 6.9 6.1 0.4 3.2 3 0 0 3 3 3 0 Delta lysin family BacteriocIIc_cy PF12173.8 KDO22698.1 - 0.048 13.9 1.0 0.073 13.3 1.0 1.3 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like PP2C PF00481.21 KDO22699.1 - 6.6e-36 124.3 0.0 9.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PIN_11 PF18479.1 KDO22700.1 - 0.011 15.9 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 PIN like domain WW PF00397.26 KDO22700.1 - 0.012 15.7 1.3 0.012 15.7 1.3 2.4 2 0 0 2 2 2 0 WW domain zf-C3HC4_3 PF13920.6 KDO22701.1 - 2.6e-10 40.0 11.7 5.1e-10 39.1 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO22701.1 - 2e-09 37.7 12.2 4.4e-09 36.5 12.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO22701.1 - 2.5e-09 36.8 12.7 5.4e-09 35.8 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO22701.1 - 6.5e-08 32.3 12.0 1.6e-07 31.1 12.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO22701.1 - 9.3e-07 28.6 12.3 1.7e-06 27.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22701.1 - 1.2e-06 28.4 11.0 2.8e-06 27.2 11.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KDO22701.1 - 2.6e-06 27.6 8.4 5.8e-06 26.5 8.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO22701.1 - 6.3e-06 26.1 5.1 6.3e-06 26.1 5.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO22701.1 - 0.0028 17.8 10.7 0.0068 16.5 10.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO22701.1 - 0.011 15.5 8.8 0.027 14.2 8.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KDO22701.1 - 0.013 15.1 7.3 0.013 15.1 7.3 1.8 2 0 0 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KDO22701.1 - 0.03 14.4 6.0 0.071 13.2 6.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 KDO22701.1 - 0.35 10.5 7.3 0.81 9.3 2.3 2.7 2 0 0 2 2 2 0 RecR protein zf-RING_11 PF17123.5 KDO22701.1 - 3.2 7.6 13.7 0.12 12.2 6.5 2.4 2 0 0 2 2 2 0 RING-like zinc finger Na_Pi_cotrans PF02690.15 KDO22702.1 - 9.8e-39 132.6 20.0 5.5e-20 71.9 5.0 2.3 2 0 0 2 2 2 2 Na+/Pi-cotransporter Rhomboid_SP PF12595.8 KDO22702.1 - 5.7 6.2 7.1 0.57 9.5 2.6 1.6 2 0 0 2 2 2 0 Rhomboid serine protease FAM184 PF15665.5 KDO22703.1 - 0.0036 17.1 14.8 0.013 15.3 6.9 2.1 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B Spc7 PF08317.11 KDO22703.1 - 6.3 5.6 15.0 4.7 6.0 11.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein PhzC-PhzF PF02567.16 KDO22704.1 - 1.4e-57 195.3 0.0 1.8e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 KDO22704.1 - 1.8e-10 41.1 0.1 5.1e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO22704.1 - 1.1e-08 35.1 0.0 2.5e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO22704.1 - 9.1e-06 26.0 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO22704.1 - 0.00058 19.9 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KDO22704.1 - 0.014 15.0 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO22704.1 - 0.023 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KDO22704.1 - 0.046 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PIG-H PF10181.9 KDO22705.1 - 1.1e-15 57.2 0.2 1.8e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Cyclin_N PF00134.23 KDO22706.1 - 5.8e-10 39.0 0.0 5.8e-10 39.0 0.0 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO22706.1 - 9.5e-06 25.7 0.1 9.5e-06 25.7 0.1 3.4 3 1 0 3 3 3 1 Cyclin, C-terminal domain Spt20 PF12090.8 KDO22706.1 - 2.1 7.9 16.7 3.5 7.2 16.7 1.3 1 0 0 1 1 1 0 Spt20 family CCDC53 PF10152.9 KDO22706.1 - 3 8.2 8.1 2.4 8.5 6.0 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 KDO22706.1 - 3.2 7.7 16.2 4.6 7.1 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 KDO22706.1 - 3.7 6.4 23.3 5.6 5.8 23.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CCDC84 PF14968.6 KDO22707.1 - 5.4e-25 88.8 13.2 7.8e-10 38.9 2.9 3.2 2 1 1 3 3 3 3 Coiled coil protein 84 Tubulin_3 PF14881.6 KDO22708.1 - 2.1e-11 43.9 0.0 3.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KDO22708.1 - 0.004 17.4 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WBS_methylT PF12589.8 KDO22709.1 - 1.2e-19 70.8 3.2 1.2e-19 70.8 3.2 1.6 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 KDO22709.1 - 3.9e-13 49.9 0.0 7.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO22709.1 - 5.1e-13 49.5 0.0 9.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO22709.1 - 1.5e-06 28.8 0.5 4.6e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO22709.1 - 9.3e-05 22.3 0.0 0.00043 20.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KDO22709.1 - 0.0003 20.6 0.1 0.032 13.9 0.0 2.7 2 1 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.6 KDO22709.1 - 0.00047 20.0 0.1 0.00082 19.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO22709.1 - 0.0016 17.8 0.0 0.0074 15.6 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KDO22709.1 - 0.0031 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KDO22709.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KDO22709.1 - 0.017 14.6 0.1 0.059 12.8 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 KDO22709.1 - 0.018 15.3 0.1 0.048 14.0 0.0 1.7 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KDO22709.1 - 0.096 12.7 1.0 0.28 11.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KDO22709.1 - 0.17 11.6 0.0 0.53 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEAD PF00270.29 KDO22710.1 - 5.9e-45 153.2 0.0 1.5e-44 151.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO22710.1 - 4.7e-31 107.4 2.2 7.6e-30 103.5 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO22710.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KDO22710.1 - 0.0061 16.8 0.0 0.025 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain Proteasome PF00227.26 KDO22711.1 - 4.1e-28 98.2 0.0 5.4e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF5066 PF16728.5 KDO22711.1 - 0.059 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Thioredoxin PF00085.20 KDO22712.1 - 9.9e-32 109.0 0.1 1.8e-31 108.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 KDO22712.1 - 1e-07 32.1 0.0 3.7e-06 27.0 0.0 2.7 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KDO22712.1 - 8.6e-06 26.2 0.1 2.7e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KDO22712.1 - 0.00094 18.6 0.0 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KDO22712.1 - 0.012 16.0 0.0 0.86 10.0 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KDO22712.1 - 0.094 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain FYVE PF01363.21 KDO22713.1 - 6.5e-15 55.0 11.4 6.5e-15 55.0 11.4 2.8 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO22713.1 - 3e-14 53.1 25.0 4.7e-14 52.4 7.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO22713.1 - 3.9e-09 36.2 8.3 3.9e-09 36.2 8.3 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO22713.1 - 5.9e-09 35.5 3.5 5.9e-09 35.5 3.5 2.3 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KDO22713.1 - 2.8e-07 30.3 4.4 2.8e-07 30.3 4.4 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22713.1 - 3.6e-07 30.4 11.3 3.6e-07 30.4 11.3 2.7 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO22713.1 - 9.3e-07 28.7 4.7 9.3e-07 28.7 4.7 3.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO22713.1 - 1e-06 28.6 3.5 1e-06 28.6 3.5 3.5 2 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO22713.1 - 1e-06 28.5 6.1 1e-06 28.5 6.1 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO22713.1 - 0.0003 20.6 5.2 0.0003 20.6 5.2 3.3 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO22713.1 - 0.0076 15.9 7.7 0.0076 15.9 7.7 3.0 2 2 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KDO22713.1 - 0.018 14.8 4.3 0.018 14.8 4.3 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KDO22713.1 - 0.019 15.0 6.4 0.019 15.0 6.4 2.4 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.16 KDO22713.1 - 0.31 11.2 17.1 0.59 10.4 8.1 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zinc-ribbons_6 PF07191.12 KDO22713.1 - 7.3 6.7 20.6 13 5.9 9.7 3.0 2 2 0 2 2 2 0 zinc-ribbons START PF01852.19 KDO22715.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.6 1 1 0 1 1 1 0 START domain bZIP_1 PF00170.21 KDO22716.1 - 0.016 15.3 11.1 0.025 14.6 11.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor POX PF07526.11 KDO22716.1 - 0.23 12.0 2.2 0.33 11.5 2.2 1.2 1 0 0 1 1 1 0 Associated with HOX RR_TM4-6 PF06459.12 KDO22716.1 - 0.41 10.4 4.3 0.49 10.2 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KDO22716.1 - 3.3 7.0 6.9 4.3 6.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ldl_recept_b PF00058.17 KDO22717.1 - 5.2e-06 26.8 5.2 0.22 12.0 0.2 5.4 6 0 0 6 6 6 2 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KDO22717.1 - 5.5e-05 22.9 2.8 0.55 9.8 0.0 4.6 2 2 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KDO22717.1 - 0.0023 17.3 0.0 0.11 11.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5050) PQQ_3 PF13570.6 KDO22717.1 - 0.0027 18.2 10.5 1.3 9.6 0.0 5.6 5 1 1 6 6 6 2 PQQ-like domain Str_synth PF03088.16 KDO22717.1 - 0.0036 17.4 0.0 12 6.1 0.0 3.5 2 1 1 3 3 3 1 Strictosidine synthase TIG PF01833.24 KDO22717.1 - 0.0086 16.1 0.2 0.038 14.1 0.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain FlxA PF14282.6 KDO22718.1 - 1.8 8.6 7.7 4.6 7.3 7.7 1.6 1 1 0 1 1 1 0 FlxA-like protein Pkinase_Tyr PF07714.17 KDO22719.1 - 3.3e-08 33.1 0.0 3.8e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22719.1 - 8.4e-08 31.9 0.0 1.4e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22720.1 - 7.1e-25 87.8 0.0 1.4e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22720.1 - 5.3e-20 71.9 0.0 8.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22721.1 - 7.7e-15 54.9 0.0 8.8e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22721.1 - 1.6e-13 50.7 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO22721.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO22721.1 - 0.055 12.8 0.0 0.086 12.1 0.0 1.4 2 0 0 2 2 2 0 Kinase-like zf-RING_2 PF13639.6 KDO22722.1 - 4e-10 39.9 7.3 6.9e-10 39.1 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO22722.1 - 3.4e-07 29.9 2.7 6.7e-07 28.9 2.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO22722.1 - 4.5e-07 29.6 8.5 8.2e-07 28.8 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22722.1 - 9.6e-07 29.0 5.1 2.2e-06 27.9 5.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO22722.1 - 1.1e-05 25.3 6.7 1.8e-05 24.6 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO22722.1 - 6.7e-05 22.7 6.8 0.00011 22.0 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22722.1 - 0.00016 21.6 2.4 0.0003 20.8 2.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO22722.1 - 0.00044 20.1 7.6 0.00072 19.4 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO22722.1 - 0.00047 20.0 7.9 0.0008 19.2 7.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO22722.1 - 0.00055 19.5 6.2 0.0011 18.6 6.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO22722.1 - 0.0045 17.0 3.5 0.01 15.9 3.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KDO22722.1 - 0.019 15.1 5.7 0.05 13.8 5.7 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KDO22722.1 - 0.19 11.8 4.1 0.42 10.7 4.1 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 KDO22722.1 - 0.33 11.3 3.7 0.7 10.3 3.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KDO22722.1 - 0.55 10.1 10.1 1 9.2 10.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KDO22722.1 - 2.1 8.5 6.0 3.9 7.7 6.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 KDO22722.1 - 2.4 8.3 9.0 5 7.3 9.0 1.5 1 0 0 1 1 1 0 RING-variant domain CUE PF02845.16 KDO22724.1 - 4e-15 55.2 4.2 0.00016 21.3 0.1 4.4 4 0 0 4 4 4 3 CUE domain Smr PF01713.21 KDO22724.1 - 2.7e-07 30.8 0.1 1e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 Smr domain MarR_2 PF12802.7 KDO22724.1 - 0.084 12.8 2.7 1.7 8.6 0.1 3.2 4 0 0 4 4 4 0 MarR family WD40 PF00400.32 KDO22725.1 - 4.9e-26 90.5 3.6 1.4e-06 28.9 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO22725.1 - 3.4e-12 46.5 0.1 0.003 17.8 0.0 5.1 5 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cnn_1N PF07989.11 KDO22727.1 - 0.1 12.8 11.4 1.3 9.2 11.4 2.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 KDO22727.1 - 0.18 11.2 4.7 0.24 10.7 4.7 1.4 1 0 0 1 1 1 0 FAM76 protein HIP1_clath_bdg PF16515.5 KDO22727.1 - 0.28 11.8 15.9 0.55 10.9 4.4 2.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3072 PF11272.8 KDO22727.1 - 0.37 10.7 4.2 0.53 10.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) CorA PF01544.18 KDO22727.1 - 1.4 8.2 5.2 2 7.7 5.2 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIVA PF05103.13 KDO22727.1 - 1.5 8.9 11.1 32 4.6 9.8 2.1 2 0 0 2 2 2 0 DivIVA protein YabA PF06156.13 KDO22727.1 - 3 8.5 10.4 2.5 8.8 2.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA PDEase_I PF00233.19 KDO22728.1 - 3.7e-67 226.5 0.8 6.1e-67 225.8 0.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2512 PF10710.9 KDO22728.1 - 0.025 14.2 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) SOGA PF11365.8 KDO22728.1 - 0.034 15.3 3.1 0.082 14.1 3.1 1.6 1 0 0 1 1 1 0 Protein SOGA DUF676 PF05057.14 KDO22729.1 - 0.0082 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Argos PF11581.8 KDO22729.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos 3HCDH_N PF02737.18 KDO22730.1 - 3.1e-36 124.9 0.0 4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KDO22730.1 - 0.0001 22.5 0.0 0.0003 21.0 0.0 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KDO22730.1 - 0.00032 20.4 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KDO22730.1 - 0.00044 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KDO22730.1 - 0.00061 19.5 0.0 0.00063 19.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 KDO22730.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KDO22730.1 - 0.0031 17.8 0.0 0.0084 16.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KDO22730.1 - 0.0058 17.2 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KDO22730.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KDO22730.1 - 0.024 14.2 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KDO22730.1 - 0.044 12.5 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KDO22730.1 - 0.054 12.7 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.25 KDO22730.1 - 0.057 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KDO22730.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KDO22730.1 - 0.09 12.1 0.8 0.32 10.3 0.4 1.9 1 1 1 2 2 2 0 ThiF family PI3_PI4_kinase PF00454.27 KDO22731.1 - 7.7e-45 153.7 0.0 1.2e-44 153.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 KDO22731.1 - 6e-19 67.9 4.6 2.3e-14 52.7 0.7 2.2 1 1 1 2 2 2 2 Serine/threonine-protein kinase smg-1 FATC PF02260.20 KDO22731.1 - 4.9e-13 48.6 1.6 1.7e-12 46.9 1.6 2.0 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 KDO22731.1 - 3.9e-05 24.0 0.0 0.00022 21.6 0.0 2.5 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FAT PF02259.23 KDO22731.1 - 0.00023 20.5 1.2 0.0046 16.2 1.2 2.3 1 1 0 1 1 1 1 FAT domain HEAT PF02985.22 KDO22731.1 - 0.082 13.2 0.8 5.1 7.6 0.1 3.9 2 0 0 2 2 2 0 HEAT repeat TFB6 PF17110.5 KDO22731.1 - 0.49 10.1 2.7 1.7 8.4 2.7 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 KDO22731.1 - 2.4 7.4 14.6 6.2 6.1 14.6 1.6 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KDO22731.1 - 2.9 6.0 7.5 7.2 4.7 7.5 1.6 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KDO22731.1 - 5.8 5.3 9.4 14 4.1 9.4 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FliJ PF02050.16 KDO22733.1 - 0.00015 22.0 7.3 0.00015 22.0 7.3 2.3 2 0 0 2 2 2 1 Flagellar FliJ protein AAA_13 PF13166.6 KDO22733.1 - 0.00041 19.1 1.4 0.00053 18.8 1.4 1.2 1 0 0 1 1 1 1 AAA domain APG17 PF04108.12 KDO22733.1 - 0.0011 18.2 3.6 0.0022 17.2 1.0 2.2 2 0 0 2 2 2 1 Autophagy protein Apg17 TelA PF05816.11 KDO22733.1 - 0.002 17.3 0.9 0.002 17.3 0.9 1.8 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) Sec8_exocyst PF04048.14 KDO22733.1 - 0.0047 16.8 2.1 0.015 15.1 0.1 2.6 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain APG6_N PF17675.1 KDO22733.1 - 0.011 16.3 3.2 0.011 16.3 3.2 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KDO22733.1 - 0.011 16.2 6.3 0.06 13.8 0.3 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 KDO22733.1 - 0.013 16.0 11.1 0.39 11.1 2.8 2.1 2 0 0 2 2 2 0 Fez1 V_ATPase_I PF01496.19 KDO22733.1 - 0.013 13.5 3.7 0.11 10.3 0.0 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4094 PF13334.6 KDO22733.1 - 0.027 14.9 0.2 0.1 13.0 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CdvA PF18822.1 KDO22733.1 - 0.05 13.4 5.7 3.6 7.4 0.2 3.0 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 KDO22733.1 - 0.07 13.2 5.0 0.5 10.4 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KDO22733.1 - 0.081 13.0 5.7 0.22 11.5 1.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 KDO22733.1 - 0.11 12.9 7.6 0.054 13.9 1.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) THOC7 PF05615.13 KDO22733.1 - 0.13 12.6 9.9 0.38 11.0 1.9 2.6 2 1 0 2 2 2 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 KDO22733.1 - 0.13 12.5 12.0 0.32 11.2 2.9 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KDO22733.1 - 0.15 10.9 7.2 0.04 12.8 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KDO22733.1 - 0.23 11.5 1.8 5.8 7.0 0.9 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3972 PF13118.6 KDO22733.1 - 0.23 11.9 1.8 0.35 11.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) V-SNARE PF05008.15 KDO22733.1 - 0.27 11.6 5.6 0.16 12.4 1.7 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Filament PF00038.21 KDO22733.1 - 0.28 10.7 10.6 0.032 13.8 3.2 2.1 2 0 0 2 2 2 0 Intermediate filament protein DUF4201 PF13870.6 KDO22733.1 - 0.31 10.8 8.0 0.05 13.3 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) WXG100 PF06013.12 KDO22733.1 - 0.64 10.3 5.9 52 4.2 3.5 3.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG YlqD PF11068.8 KDO22733.1 - 0.88 10.0 7.4 0.76 10.2 2.6 2.4 2 1 0 2 2 2 0 YlqD protein SlyX PF04102.12 KDO22733.1 - 1.5 9.5 16.2 0.11 13.2 2.6 4.4 3 1 1 4 4 4 0 SlyX MutS_III PF05192.18 KDO22733.1 - 1.7 8.8 4.6 0.65 10.2 1.1 1.8 1 1 1 2 2 2 0 MutS domain III ADIP PF11559.8 KDO22733.1 - 1.8 8.6 12.9 1.7 8.8 5.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF601 PF04642.12 KDO22733.1 - 2.2 7.7 6.9 0.15 11.6 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF601 Laminin_II PF06009.12 KDO22733.1 - 2.5 8.1 9.7 0.94 9.5 4.7 2.4 2 1 1 3 3 3 0 Laminin Domain II Seryl_tRNA_N PF02403.22 KDO22733.1 - 3 8.1 6.1 1.2 9.4 1.8 2.5 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 KDO22733.1 - 3.8 6.8 6.5 6.1 6.1 1.6 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF724 PF05266.14 KDO22733.1 - 4.1 7.2 8.6 0.49 10.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 KDO22733.1 - 6.2 6.1 10.4 0.55 9.6 4.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KDO22733.1 - 6.7 7.2 12.8 4.2 7.9 1.1 3.6 2 2 1 3 3 3 0 Cell division protein ZapB VPS28 PF03997.12 KDO22734.1 - 0.14 11.9 6.5 0.14 11.8 2.8 2.3 2 0 0 2 2 2 0 VPS28 protein NPBW PF15180.6 KDO22734.1 - 0.23 11.3 3.0 2.3 8.1 3.0 2.5 1 1 0 1 1 1 0 Neuropeptides B and W ThiF PF00899.21 KDO22736.1 - 0.00099 18.5 1.4 0.0013 18.1 1.4 1.2 1 0 0 1 1 1 1 ThiF family Myb_DNA-binding PF00249.31 KDO22738.1 - 4.5e-43 145.2 7.7 3.1e-14 52.9 0.3 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO22738.1 - 7.6e-37 125.4 0.7 7.1e-13 48.6 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO22738.1 - 0.0085 16.0 0.0 0.54 10.2 0.0 2.6 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 KDO22738.1 - 0.022 14.8 0.0 5.1 7.1 0.0 2.7 2 1 0 2 2 2 0 SLIDE Rap1_C PF11626.8 KDO22738.1 - 0.12 12.5 1.5 20 5.3 1.5 3.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PseudoU_synth_2 PF00849.22 KDO22739.1 - 3.6e-20 72.7 0.0 7.1e-19 68.5 0.0 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase HMG_box PF00505.19 KDO22739.1 - 0.039 14.4 0.4 0.076 13.4 0.4 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Hrs_helical PF12210.8 KDO22739.1 - 0.56 10.8 1.8 0.96 10.0 1.8 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TPR_12 PF13424.6 KDO22740.1 - 3.3e-12 46.5 5.3 1.4e-07 31.7 0.5 3.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO22740.1 - 8.7e-06 25.5 1.3 0.48 10.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO22740.1 - 0.00024 20.9 0.9 12 6.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO22740.1 - 0.0026 17.7 0.2 0.55 10.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO22740.1 - 0.0093 15.8 0.3 2.8 7.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO22740.1 - 0.34 11.8 4.4 14 6.8 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF676 PF05057.14 KDO22741.1 - 0.091 12.3 0.1 0.32 10.5 0.0 1.7 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Acyltransferase PF01553.21 KDO22742.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase HECT PF00632.25 KDO22743.1 - 1.1e-47 163.0 0.0 2e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KDO22743.1 - 3.4e-41 140.1 0.0 2.2e-15 56.8 0.0 4.5 4 0 0 4 4 4 4 SPRY domain Laminin_G_3 PF13385.6 KDO22743.1 - 7.1e-05 23.0 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 KDO22743.1 - 7.6e-05 22.5 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain MORN PF02493.20 KDO22743.1 - 0.00023 20.8 2.0 0.29 11.1 0.6 2.9 2 0 0 2 2 2 2 MORN repeat zf-RanBP PF00641.18 KDO22743.1 - 0.0037 16.5 3.2 0.0095 15.2 3.2 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Pro_isomerase PF00160.21 KDO22744.1 - 6.3e-48 163.0 0.1 1.4e-47 161.9 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KDO22744.1 - 2.3e-18 66.2 0.3 7.3e-06 26.6 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO22744.1 - 1.3e-06 27.6 2.1 0.0013 17.8 0.0 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KDO22744.1 - 1.9e-05 24.9 0.0 0.022 15.1 0.0 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-ISL3 PF14690.6 KDO22745.1 - 0.0028 18.3 5.5 0.22 12.2 0.1 3.0 3 0 0 3 3 3 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Cep57_CLD_2 PF14197.6 KDO22745.1 - 0.08 13.0 0.5 14 5.9 0.2 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 zf-ribbon_3 PF13248.6 KDO22745.1 - 0.32 10.4 13.1 1.4 8.5 0.2 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KDO22745.1 - 0.33 10.7 8.7 1.1 9.1 0.6 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KDO22745.1 - 0.83 9.7 6.0 13 5.9 0.5 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KDO22745.1 - 1.1 9.5 7.3 7.7 6.7 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-tcix PF14952.6 KDO22745.1 - 3.3 7.4 6.8 1.8 8.2 1.5 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Lar_restr_allev PF14354.6 KDO22745.1 - 3.3 8.1 8.4 4.9 7.6 2.1 3.3 3 1 0 3 3 3 0 Restriction alleviation protein Lar UPF0547 PF10571.9 KDO22745.1 - 9.9 6.4 8.5 11 6.3 1.6 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Peptidase_C1 PF00112.23 KDO22746.1 - 5.5e-74 248.9 0.7 5.5e-74 248.9 0.7 1.8 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KDO22746.1 - 1.8e-11 44.3 0.1 2.9e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KDO22746.1 - 0.0001 21.3 2.4 0.014 14.2 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family La PF05383.17 KDO22747.1 - 5.9e-16 58.3 0.0 9.3e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 La domain DTW PF03942.15 KDO22748.1 - 7.2e-41 140.1 0.0 1.1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 DTW domain CBS PF00571.28 KDO22749.1 - 3.3e-31 107.5 9.9 8.7e-08 32.5 0.2 4.6 4 1 0 4 4 4 4 CBS domain DisA_N PF02457.16 KDO22749.1 - 0.0038 16.8 0.5 6.3 6.4 0.0 3.0 2 1 1 3 3 3 2 DisA bacterial checkpoint controller nucleotide-binding DUF4616 PF15394.6 KDO22749.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) DUF2025 PF09634.10 KDO22749.1 - 0.064 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) PA PF02225.22 KDO22750.1 - 9.7e-12 44.8 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 PA domain UBA PF00627.31 KDO22752.1 - 2.5e-12 46.4 0.8 4e-12 45.8 0.8 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 KDO22752.1 - 0.0001 22.3 8.7 0.00024 21.1 8.7 1.7 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 KDO22752.1 - 0.00031 20.7 1.9 0.00048 20.1 1.9 1.4 1 1 0 1 1 1 1 Der1-like family CUE PF02845.16 KDO22752.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KDO22752.1 - 0.009 15.8 1.2 0.016 15.0 1.2 1.4 1 0 0 1 1 1 1 UBA-like domain DUF1751 PF08551.10 KDO22752.1 - 0.022 15.3 0.3 0.048 14.2 0.3 1.6 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) RuvA_C PF07499.13 KDO22752.1 - 0.11 12.9 0.4 0.19 12.2 0.4 1.3 1 0 0 1 1 1 0 RuvA, C-terminal domain zf-RING_2 PF13639.6 KDO22753.1 - 3.5e-10 40.1 4.4 3.5e-10 40.1 4.4 4.1 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 KDO22753.1 - 4e-08 33.0 4.4 4e-08 33.0 4.4 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22753.1 - 1.2e-07 31.6 0.7 1.2e-07 31.6 0.7 3.7 3 2 1 4 4 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO22753.1 - 1.4e-07 31.1 3.3 1.4e-07 31.1 3.3 2.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO22753.1 - 1.9e-07 30.8 5.1 1.9e-07 30.8 5.1 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO22753.1 - 8.7e-06 25.6 4.0 8.7e-06 25.6 4.0 4.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO22753.1 - 0.00022 21.0 3.1 0.00022 21.0 3.1 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22753.1 - 0.00037 20.7 7.4 0.00037 20.7 7.4 3.8 4 1 0 4 4 4 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KDO22753.1 - 0.00043 20.4 4.6 0.00043 20.4 4.6 4.5 3 2 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KDO22753.1 - 0.00068 19.6 3.3 0.00068 19.6 3.3 3.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO22753.1 - 0.0051 16.4 1.7 0.0051 16.4 1.7 3.5 4 1 0 4 4 3 1 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 KDO22753.1 - 0.049 13.9 0.9 0.15 12.4 0.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) LisH_2 PF16045.5 KDO22753.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 LisH DZR PF12773.7 KDO22753.1 - 0.46 10.5 25.2 18 5.4 0.4 4.6 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KDO22753.1 - 1.9 8.5 15.2 47 4.1 0.1 4.2 2 1 1 3 3 3 0 zinc-ribbons Elf1 PF05129.13 KDO22753.1 - 2 8.5 7.0 22 5.2 0.0 3.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_2 PF13639.6 KDO22754.1 - 1.5e-11 44.5 4.7 2.8e-11 43.6 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO22754.1 - 8.7e-10 38.2 3.9 8.7e-10 38.2 3.9 2.3 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO22754.1 - 1.3e-08 34.5 5.0 2.6e-08 33.6 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO22754.1 - 2.4e-07 30.7 0.9 2.4e-07 30.7 0.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO22754.1 - 5.6e-07 29.3 6.1 5.6e-07 29.3 6.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO22754.1 - 1.2e-06 28.7 7.5 1.1e-05 25.6 7.6 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO22754.1 - 2.5e-06 27.3 5.3 4.6e-06 26.5 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO22754.1 - 6.7e-06 26.1 2.3 2.3e-05 24.4 2.3 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KDO22754.1 - 9.6e-06 25.3 3.1 9.6e-06 25.3 3.1 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KDO22754.1 - 1.8e-05 24.5 2.4 3.9e-05 23.4 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO22754.1 - 0.00025 21.2 4.2 0.00025 21.2 4.2 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING PHD PF00628.29 KDO22754.1 - 0.0051 16.7 4.5 0.017 15.0 4.5 1.9 1 1 0 1 1 1 1 PHD-finger zf-TFIIIC PF12660.7 KDO22754.1 - 0.0085 16.0 0.6 0.91 9.5 0.0 2.1 1 1 1 2 2 2 2 Putative zinc-finger of transcription factor IIIC complex Prok-RING_1 PF14446.6 KDO22754.1 - 0.012 15.5 5.7 0.046 13.7 0.3 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KDO22754.1 - 0.014 15.0 2.3 0.027 14.1 2.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RecR PF02132.15 KDO22754.1 - 0.024 14.2 2.1 0.77 9.4 0.2 2.4 2 0 0 2 2 2 0 RecR protein zf-Di19 PF05605.12 KDO22754.1 - 0.041 14.2 4.5 0.78 10.1 2.2 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-HC5HC2H_2 PF13832.6 KDO22754.1 - 0.056 13.6 3.6 0.17 12.1 3.2 1.7 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO22754.1 - 0.062 13.6 3.7 0.42 10.9 3.6 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain Prok-RING_4 PF14447.6 KDO22754.1 - 0.079 12.8 8.0 11 6.0 0.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn-ribbon_8 PF09723.10 KDO22754.1 - 0.1 12.7 8.0 0.2 11.8 1.7 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 KDO22754.1 - 0.14 12.7 5.7 5.5 7.5 0.2 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF5318 PF17249.2 KDO22754.1 - 0.3 10.9 1.6 4.4 7.1 0.2 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5318) zf-WRNIP1_ubi PF18279.1 KDO22754.1 - 0.98 10.2 6.1 3.6 8.4 0.7 3.1 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain FANCL_C PF11793.8 KDO22754.1 - 1.2 9.4 7.5 6.8 7.0 6.6 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 KDO22754.1 - 8 6.9 7.9 44 4.5 8.1 2.1 1 1 1 2 2 2 0 RING-like domain FPN1 PF06963.12 KDO22755.1 - 1.7e-90 303.7 33.2 1.7e-89 300.4 33.2 1.9 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Myosin_head PF00063.21 KDO22756.1 - 1e-205 685.0 0.0 1.5e-205 684.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Aida_C2 PF14186.6 KDO22756.1 - 3e-15 56.1 0.0 9.6e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal adhesion Ank_2 PF12796.7 KDO22756.1 - 4.5e-14 52.8 1.7 6.4e-08 33.1 0.4 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22756.1 - 2.4e-09 37.6 5.4 0.005 17.4 1.4 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 KDO22756.1 - 3e-09 37.3 0.1 9.6e-09 35.7 0.1 2.0 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KDO22756.1 - 2.4e-07 30.5 2.0 3.7 8.4 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KDO22756.1 - 3.4e-07 30.4 5.6 1.1 9.9 0.0 5.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO22756.1 - 5.2e-06 26.6 4.2 0.62 10.5 0.1 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) IQ PF00612.27 KDO22756.1 - 2.9e-05 23.5 80.7 0.0085 15.8 1.4 11.4 11 0 0 11 11 11 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KDO22756.1 - 0.093 12.6 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KDO22756.1 - 0.18 12.1 1.0 0.61 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO22756.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.6 2 1 0 2 2 1 0 AAA ATPase domain IMS PF00817.20 KDO22757.1 - 1.3e-36 125.9 0.0 2.6e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KDO22757.1 - 8.4e-15 55.5 0.0 2.3e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KDO22757.1 - 1.5e-12 47.7 0.0 2.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO22757.1 - 7.4e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UBM PF14377.6 KDO22757.1 - 3.3e-08 32.7 10.3 0.001 18.4 0.3 3.7 3 0 0 3 3 3 3 Ubiquitin binding region PTCB-BRCT PF12738.7 KDO22757.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 KDO22757.1 - 1.8e-05 24.8 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KDO22757.1 - 6.1e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Myb_DNA-binding PF00249.31 KDO22758.1 - 1.4e-58 194.9 4.6 1.5e-11 44.3 0.0 5.1 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO22758.1 - 3.1e-49 165.1 0.1 2.6e-13 50.0 0.0 5.0 3 2 2 5 5 5 5 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KDO22758.1 - 2.9e-05 24.2 0.8 0.26 11.5 0.0 4.4 2 2 3 5 5 5 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KDO22758.1 - 9.7e-05 22.4 0.0 1.7 8.8 0.0 4.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KDO22758.1 - 0.00052 20.4 10.4 0.02 15.3 0.0 5.0 3 1 2 5 5 5 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO22758.1 - 0.0013 18.5 0.0 2.3 8.2 0.0 4.1 3 3 1 4 4 4 1 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 KDO22758.1 - 0.16 12.1 7.4 6.2 7.0 2.0 4.5 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain Cellulase PF00150.18 KDO22759.1 - 9.9e-14 51.4 0.1 2.3e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KDO22760.1 - 1.1e-22 80.8 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TGF_beta_GS PF08515.12 KDO22760.1 - 0.11 12.0 0.5 0.24 10.9 0.5 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif DUF5305 PF17231.2 KDO22760.1 - 0.16 11.4 0.0 3.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Thioredoxin_6 PF13848.6 KDO22761.1 - 2.4e-05 24.3 0.0 0.0024 17.8 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 KDO22761.1 - 8.2e-05 22.5 0.0 0.00065 19.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin COX2-transmemb PF09125.10 KDO22762.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Cellulase PF00150.18 KDO22763.1 - 4.9e-21 75.4 0.0 6.4e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5411 PF17424.2 KDO22763.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5411) YedD PF13987.6 KDO22764.1 - 0.13 12.0 0.1 0.56 10.0 0.0 1.8 1 1 0 1 1 1 0 YedD-like protein Orn_Arg_deC_N PF02784.16 KDO22765.1 - 1.6e-38 132.5 0.0 2e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KDO22765.1 - 5.2e-19 68.3 0.0 5.5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AhpC-TSA PF00578.21 KDO22766.1 - 8.4e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO22766.1 - 3e-05 23.8 0.1 5.7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KDO22766.1 - 0.00016 22.0 0.1 0.00044 20.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO22766.1 - 0.00023 21.1 0.0 0.00074 19.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO22766.1 - 0.00097 19.6 0.1 0.002 18.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO22766.1 - 0.065 13.4 0.1 0.19 12.0 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like cNMP_binding PF00027.29 KDO22767.1 - 4.8e-18 65.0 0.6 3.5e-11 43.0 0.1 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Peptidase_M8 PF01457.16 KDO22768.1 - 3.2e-103 346.2 0.6 6.8e-103 345.1 0.6 1.5 1 1 0 1 1 1 1 Leishmanolysin EGF_2 PF07974.13 KDO22768.1 - 2.7e-20 72.4 134.7 4.6e-05 23.7 8.3 9.4 8 1 0 8 8 8 7 EGF-like domain DUF3626 PF12294.8 KDO22768.1 - 0.00099 18.3 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3626) EGF PF00008.27 KDO22768.1 - 0.0027 18.0 20.1 0.0049 17.2 3.9 9.3 8 0 0 8 8 8 4 EGF-like domain UPF0669 PF17065.5 KDO22768.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 DUF2773 PF10971.8 KDO22768.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) RRM_1 PF00076.22 KDO22769.1 - 2.3e-14 53.0 0.0 3.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.19 KDO22771.1 - 3.7e-261 868.6 0.0 4.3e-261 868.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YqhR PF11085.8 KDO22771.1 - 0.94 9.4 5.6 0.24 11.3 2.0 1.9 2 0 0 2 2 2 0 Conserved membrane protein YqhR DctM PF06808.12 KDO22772.1 - 0.002 17.1 0.7 0.0023 16.8 0.7 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Gly-zipper_Omp PF13488.6 KDO22772.1 - 0.0065 16.4 2.8 0.011 15.7 2.8 1.3 1 1 0 1 1 1 1 Glycine zipper Cation_efflux PF01545.21 KDO22774.1 - 1.8e-48 164.9 0.9 2.7e-48 164.4 0.9 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 KDO22774.1 - 0.00013 21.3 7.2 0.00032 20.0 7.2 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4766 PF15973.5 KDO22774.1 - 0.26 11.9 18.7 0.46 11.1 18.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) FYVE PF01363.21 KDO22775.1 - 8.6e-15 54.6 10.8 1.6e-14 53.8 10.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO22775.1 - 2.5 8.4 8.9 3.6 7.8 8.1 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger Zf_RING PF16744.5 KDO22775.1 - 3.4 7.9 8.9 7.8 6.7 8.9 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger FYVE PF01363.21 KDO22776.1 - 1.6e-05 24.9 10.8 4.3e-05 23.6 10.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO22776.1 - 0.00096 19.4 8.6 0.0021 18.2 8.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Peptidase_C92 PF05708.12 KDO22776.1 - 0.0097 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family C1_1 PF00130.22 KDO22776.1 - 0.077 12.9 7.4 0.26 11.2 6.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4428 PF14471.6 KDO22776.1 - 0.16 11.9 6.6 6.4 6.8 6.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-Dof PF02701.15 KDO22776.1 - 0.23 11.6 6.3 0.7 10.1 6.3 1.8 1 0 0 1 1 1 0 Dof domain, zinc finger Siva PF05458.12 KDO22776.1 - 3.8 7.2 11.3 7.4 6.2 11.3 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PLAC8 PF04749.17 KDO22778.1 - 1.5e-18 67.6 20.4 2.9e-18 66.7 20.4 1.5 1 0 0 1 1 1 1 PLAC8 family LPMO_10 PF03067.15 KDO22779.1 - 1e-23 85.0 0.6 1.6e-23 84.4 0.0 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_1 PF00734.18 KDO22779.1 - 2.1e-11 43.6 8.3 6.7e-11 41.9 8.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain MGC-24 PF05283.11 KDO22779.1 - 0.9 10.0 7.6 0.12 12.8 2.8 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trypan_PARP PF05887.11 KDO22779.1 - 2.9 7.9 10.1 0.63 10.0 4.4 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 KDO22779.1 - 3.1 6.9 4.7 4.6 6.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MMR_HSR1 PF01926.23 KDO22780.1 - 0.00044 20.3 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lipase_3 PF01764.25 KDO22780.1 - 0.023 14.5 0.1 0.065 13.1 0.1 1.8 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO22780.1 - 0.061 13.9 0.1 0.061 13.9 0.1 3.4 3 1 0 3 3 3 0 Alpha/beta hydrolase family Dynamin_N PF00350.23 KDO22780.1 - 0.07 13.2 0.0 5.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DUF2974 PF11187.8 KDO22780.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3226 PF11536.8 KDO22780.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) DUF3107 PF11305.8 KDO22780.1 - 0.2 11.9 0.6 1.1 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) PUL PF08324.11 KDO22781.1 - 9.2e-34 116.9 5.8 1.4e-33 116.3 5.8 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KDO22781.1 - 5.3e-22 78.2 0.0 9.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KDO22781.1 - 2.9e-17 62.7 17.2 0.00024 21.8 1.3 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Got1 PF04178.12 KDO22782.1 - 4.5e-29 101.1 16.1 7.3e-29 100.5 16.1 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family COX15-CtaA PF02628.15 KDO22782.1 - 0.012 14.8 6.5 0.012 14.8 6.5 1.3 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein Ribo_biogen_C PF04034.13 KDO22782.1 - 0.04 13.6 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal PTPS_related PF10131.9 KDO22782.1 - 0.12 10.7 9.5 0.15 10.3 9.5 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF3989 PF13150.6 KDO22782.1 - 0.27 11.0 2.2 0.62 9.8 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3989) YfhO PF09586.10 KDO22782.1 - 1 7.5 8.3 1.2 7.3 8.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2157 PF09925.9 KDO22782.1 - 1.5 8.6 16.9 21 4.9 16.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Trp_oprn_chp PF09534.10 KDO22782.1 - 2.2 8.0 8.3 12 5.7 4.5 2.3 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Claudin_3 PF06653.11 KDO22783.1 - 0.1 12.6 10.5 0.17 11.8 1.2 2.5 2 1 0 2 2 2 0 Tight junction protein, Claudin-like EamA PF00892.20 KDO22785.1 - 1e-15 58.1 38.4 1.6e-11 44.5 17.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO22785.1 - 0.0003 20.2 4.9 0.0003 20.2 4.9 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 KDO22786.1 - 1e-17 64.6 36.7 3.7e-11 43.3 18.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO22786.1 - 0.0002 20.8 1.5 0.0002 20.8 1.5 2.2 1 1 1 2 2 2 1 Triose-phosphate Transporter family Ank_4 PF13637.6 KDO22788.1 - 1.1e-18 67.4 0.0 5.7e-08 33.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22788.1 - 3.8e-17 62.1 0.0 2.4e-05 24.5 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22788.1 - 8.6e-17 61.5 0.0 5.7e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO22788.1 - 1.3e-13 49.8 0.1 3.1e-05 24.0 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO22788.1 - 1.6e-13 50.4 0.2 0.00075 19.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat XOO_2897-deam PF14440.6 KDO22789.1 - 0.16 12.1 4.4 0.41 10.8 0.3 2.5 1 1 2 3 3 3 0 Xanthomonas XOO_2897-like deaminase Iso_dh PF00180.20 KDO22789.1 - 0.54 9.3 2.4 0.62 9.2 2.4 1.1 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Glutaredoxin2_C PF04399.13 KDO22789.1 - 0.84 9.5 6.1 0.29 11.0 1.1 2.2 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain IPK PF03770.16 KDO22789.1 - 1.1 9.1 5.0 1.4 8.8 5.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase USP8_interact PF08941.10 KDO22789.1 - 4 7.2 6.5 0.5 10.2 0.9 2.1 1 1 0 2 2 2 0 USP8 interacting Oxidored_FMN PF00724.20 KDO22790.1 - 9.1e-91 304.6 0.0 1e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KDO22790.1 - 0.0027 17.2 0.2 0.82 9.1 0.0 2.9 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel Oxidored_FMN PF00724.20 KDO22791.1 - 1.6e-90 303.8 0.0 1.9e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KDO22791.1 - 0.0026 17.2 0.2 0.83 9.0 0.0 2.9 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel DUF768 PF05589.11 KDO22792.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF768) bZIP_1 PF00170.21 KDO22793.1 - 0.34 11.0 5.1 0.098 12.8 1.3 1.9 2 0 0 2 2 2 0 bZIP transcription factor AT_hook PF02178.19 KDO22793.1 - 6.5 7.0 10.3 14 6.0 10.3 1.6 1 0 0 1 1 1 0 AT hook motif Oxidored_FMN PF00724.20 KDO22796.1 - 8.6e-85 285.0 0.0 9.9e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KDO22796.1 - 0.044 13.2 0.2 12 5.2 0.0 2.9 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel DUF4928 PF16280.5 KDO22796.1 - 0.064 12.5 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) Oxidored_FMN PF00724.20 KDO22797.1 - 1.1e-71 241.9 0.0 1.3e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KDO22798.1 - 3.3e-87 292.9 0.0 3.9e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf-RVT PF13966.6 KDO22799.1 - 0.0029 18.3 0.2 0.0064 17.2 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Sugar_tr PF00083.24 KDO22800.1 - 8.5e-28 97.4 5.1 1e-27 97.1 5.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO22800.1 - 3e-21 75.8 8.6 3.8e-21 75.4 8.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KDO22800.1 - 0.11 11.0 7.1 0.12 10.9 5.3 1.8 1 1 1 2 2 2 0 MFS/sugar transport protein VirB3 PF05101.13 KDO22800.1 - 7 7.0 6.7 0.73 10.1 1.0 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Pkinase_Tyr PF07714.17 KDO22801.1 - 1.7e-12 47.2 0.1 1.9e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22801.1 - 1.9e-12 47.1 0.0 3.2e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 KDO22804.1 - 2.1e-15 55.4 1.1 0.0023 17.8 0.0 6.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_8 PF13855.6 KDO22804.1 - 8.1e-05 22.3 0.0 0.015 15.0 0.0 4.4 4 2 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KDO22804.1 - 0.00013 22.3 8.6 0.022 15.1 0.0 5.2 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO22804.1 - 0.00013 21.6 0.5 0.00085 18.9 0.3 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KDO22804.1 - 0.038 14.5 0.1 75 4.5 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat HECT PF00632.25 KDO22805.1 - 2e-67 227.9 0.0 3e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps36-NZF-N PF16988.5 KDO22805.1 - 0.043 13.2 0.6 0.091 12.2 0.6 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KDO22805.1 - 0.048 13.0 4.7 0.099 12.0 4.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FAT PF02259.23 KDO22806.1 - 7.9e-79 265.4 0.6 1.7e-78 264.3 0.6 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KDO22806.1 - 1.8e-71 240.9 0.1 3.1e-71 240.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KDO22806.1 - 2.4e-44 149.8 3.6 7.5e-44 148.2 0.1 3.3 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 KDO22806.1 - 3e-44 150.8 2.6 2.3e-43 147.9 0.1 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.20 KDO22806.1 - 6.2e-17 61.1 0.7 1.7e-16 59.7 0.7 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KDO22806.1 - 3.8e-08 33.6 17.8 0.16 12.4 0.0 8.4 6 1 0 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO22806.1 - 0.00065 20.3 0.2 2.2 8.9 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO22806.1 - 0.0021 18.1 2.0 0.93 9.5 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KDO22806.1 - 0.0054 16.9 29.6 5.1 7.6 0.0 11.7 13 0 0 13 13 12 1 HEAT repeat ParcG PF10274.9 KDO22806.1 - 0.012 15.7 0.6 2.8 8.0 0.0 3.8 3 0 0 3 3 3 0 Parkin co-regulated protein IFRD PF05004.13 KDO22806.1 - 0.024 13.8 6.1 0.26 10.4 0.2 3.4 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) TPR_7 PF13176.6 KDO22806.1 - 0.086 12.9 1.3 17 5.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4126 PF13548.6 KDO22806.1 - 0.15 11.8 1.0 0.67 9.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) TrkH PF02386.16 KDO22806.1 - 0.22 9.9 0.1 0.41 9.0 0.1 1.3 1 0 0 1 1 1 0 Cation transport protein HECT PF00632.25 KDO22807.1 - 2e-67 227.9 0.0 2.2e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ETF PF01012.21 KDO22809.1 - 8.5e-45 152.9 1.3 1.1e-44 152.5 1.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pan3_PK PF18101.1 KDO22810.1 - 8.2e-53 178.1 0.2 1.2e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain V-ATPase_G PF03179.15 KDO22811.1 - 1.6e-24 86.5 9.3 1.9e-24 86.2 9.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KDO22811.1 - 0.012 15.0 11.5 0.02 14.3 11.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) SNAPc_SNAP43 PF09808.9 KDO22811.1 - 0.031 14.2 0.6 0.034 14.1 0.6 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF2340 PF10209.9 KDO22811.1 - 0.054 14.0 0.3 0.1 13.0 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) ATP-synt_B PF00430.18 KDO22811.1 - 1.2 9.3 11.7 0.77 9.8 9.4 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) MRP-S26 PF14943.6 KDO22811.1 - 2 8.3 10.7 1.3 8.9 4.9 2.0 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Ank_2 PF12796.7 KDO22813.1 - 7.6e-08 32.8 0.1 0.0012 19.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO22813.1 - 0.15 12.6 1.1 1.4 9.5 0.2 2.7 2 1 0 2 2 2 0 Ankyrin repeat AhpC-TSA PF00578.21 KDO22815.1 - 2.1e-38 131.0 0.0 4.1e-38 130.1 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KDO22815.1 - 2.2e-16 59.9 0.0 3.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KDO22815.1 - 2.3e-13 49.8 0.1 4.1e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KDO22815.1 - 0.028 14.3 0.1 0.064 13.2 0.0 1.7 2 1 0 2 2 2 0 SCO1/SenC Lung_7-TM_R PF06814.13 KDO22816.1 - 2.4e-49 168.2 14.0 3e-49 167.9 14.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KDO22816.1 - 0.00071 19.1 16.6 0.0014 18.0 16.4 1.6 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Peptidase_C25_C PF03785.14 KDO22816.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain EF-hand_1 PF00036.32 KDO22817.1 - 6.8e-25 84.7 4.7 8.7e-06 24.9 0.0 6.3 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 KDO22817.1 - 5.6e-21 74.8 3.6 1.7e-07 31.6 0.4 4.2 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO22817.1 - 7.8e-20 69.1 4.5 0.00045 19.9 0.4 6.5 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 KDO22817.1 - 5.1e-11 41.5 6.8 0.00081 18.8 0.1 6.0 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KDO22817.1 - 1.1e-07 31.6 10.5 0.046 13.6 0.2 5.7 4 1 2 6 6 6 5 EF-hand domain pair Sun2_CC2 PF18580.1 KDO22817.1 - 1.7 9.0 5.8 19 5.5 0.1 3.2 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 MCU PF04678.13 KDO22819.1 - 1.3e-28 100.3 1.8 2.1e-28 99.6 1.8 1.6 1 1 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 KDO22819.1 - 0.0008 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain PAN_4 PF14295.6 KDO22820.1 - 2e-39 133.3 62.3 7.5e-09 35.4 2.6 8.0 8 0 0 8 8 8 7 PAN domain PAN_1 PF00024.26 KDO22820.1 - 1.2e-34 118.1 39.4 1.1e-05 25.2 0.9 9.3 6 3 3 9 9 9 8 PAN domain PIG-L PF02585.17 KDO22820.1 - 4.4e-05 24.1 0.0 7.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_3 PF08277.12 KDO22820.1 - 0.035 13.9 0.1 0.035 13.9 0.1 6.2 8 0 0 8 8 8 0 PAN-like domain Pkinase PF00069.25 KDO22821.1 - 2e-48 165.0 0.0 3e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22821.1 - 8.1e-48 163.0 0.0 1.1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_E3_CR2 PF02439.15 KDO22821.1 - 0.006 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Haspin_kinase PF12330.8 KDO22821.1 - 0.022 13.7 0.0 0.13 11.2 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO22821.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EphA2_TM PF14575.6 KDO22821.1 - 0.12 13.3 0.0 0.59 11.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2093 PF09866.9 KDO22822.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Transglut_core PF01841.19 KDO22824.1 - 1.5e-11 44.7 0.1 3.1e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core3 PF13471.6 KDO22824.1 - 0.0039 17.1 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pkinase_Tyr PF07714.17 KDO22825.1 - 2.8e-46 157.9 0.0 4.2e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22825.1 - 7.1e-44 150.2 0.0 9.9e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO22825.1 - 0.036 13.0 0.0 0.26 10.2 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO22825.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ACOX PF01756.19 KDO22826.1 - 2.2e-46 157.7 0.1 6.3e-46 156.2 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KDO22826.1 - 4.5e-23 82.1 0.1 8.3e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KDO22826.1 - 8.8e-14 51.5 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KDO22827.1 - 2.3e-45 154.4 0.0 4.7e-45 153.4 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KDO22827.1 - 2.7e-25 89.3 0.1 5.3e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KDO22827.1 - 6.5e-15 55.1 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain VitK2_biosynth PF02621.14 KDO22827.1 - 0.03 13.9 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis CAAD PF14159.6 KDO22827.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Phage_holin_7_1 PF16081.5 KDO22828.1 - 0.11 12.6 3.3 0.1 12.8 0.5 2.1 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family PCI PF01399.27 KDO22829.1 - 0.0025 18.3 3.3 0.0069 16.9 0.0 3.0 3 0 0 3 3 3 1 PCI domain DUF1967 PF09269.11 KDO22829.1 - 0.046 13.6 3.5 0.085 12.8 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) MAP7 PF05672.11 KDO22829.1 - 0.72 9.5 60.0 0.71 9.5 27.5 2.8 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Ribosomal_L1 PF00687.21 KDO22831.1 - 4.5e-53 180.0 0.0 5.7e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family P2 PF07194.11 KDO22831.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 P2 response regulator binding domain tRNA-synt_1d PF00750.19 KDO22832.1 - 8.4e-68 228.9 0.0 1.4e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KDO22832.1 - 7e-21 74.6 0.1 1.5e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1 PF00133.22 KDO22832.1 - 0.00036 18.9 0.1 0.013 13.7 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KDO22832.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Arg_tRNA_synt_N PF03485.16 KDO22832.1 - 0.016 15.8 0.0 0.056 14.0 0.0 1.9 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain DUF1786 PF08735.10 KDO22832.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Halogen_Hydrol PF10112.9 KDO22833.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pkinase_Tyr PF07714.17 KDO22834.1 - 1.2e-47 162.4 0.0 1.6e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22834.1 - 1.5e-45 155.7 0.0 1.9e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO22834.1 - 0.00097 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO22834.1 - 0.066 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KDO22834.1 - 0.11 11.5 0.0 0.37 9.7 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO22834.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SET PF00856.28 KDO22835.1 - 7.7e-12 45.9 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 SET domain P_C10 PF14974.6 KDO22835.1 - 0.19 11.8 0.4 0.78 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein C10 DUF4611 PF15387.6 KDO22835.1 - 0.26 11.6 1.7 0.54 10.5 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zinc-ribbons_6 PF07191.12 KDO22835.1 - 0.56 10.2 6.7 1.8 8.6 6.7 1.9 1 0 0 1 1 1 0 zinc-ribbons DUF4604 PF15377.6 KDO22840.1 - 3.1 8.2 25.1 2.7e+02 1.9 25.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Arm PF00514.23 KDO22841.1 - 1.2e-78 257.0 74.0 5.7e-07 29.4 0.0 26.6 27 0 0 27 27 27 21 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO22841.1 - 3e-13 49.9 37.5 0.047 14.1 1.7 11.5 7 3 3 11 11 11 8 HEAT repeats Arm_2 PF04826.13 KDO22841.1 - 1.1e-11 44.7 8.8 0.072 12.5 0.0 8.4 6 2 2 8 8 8 4 Armadillo-like HEAT_EZ PF13513.6 KDO22841.1 - 6.7e-06 26.5 39.3 0.26 11.8 0.1 11.2 11 2 2 13 13 13 4 HEAT-like repeat RICTOR_N PF14664.6 KDO22841.1 - 0.098 11.6 3.1 2.6 7.0 0.2 4.1 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, N-term HEAT PF02985.22 KDO22841.1 - 0.2 12.0 53.4 1.4 9.4 0.0 13.3 15 0 0 15 15 15 0 HEAT repeat CLASP_N PF12348.8 KDO22841.1 - 0.35 10.4 5.3 2.7 7.5 0.0 3.7 5 0 0 5 5 5 0 CLASP N terminal V-ATPase_H_N PF03224.14 KDO22842.1 - 0.015 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H HEAT_2 PF13646.6 KDO22842.1 - 0.051 14.0 3.6 3.4 8.1 0.0 3.4 2 1 1 3 3 3 0 HEAT repeats RICTOR_V PF14668.6 KDO22842.1 - 0.15 12.3 0.1 0.82 9.9 0.0 2.1 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Pkinase PF00069.25 KDO22843.1 - 9.4e-36 123.5 0.0 9.8e-34 116.9 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22843.1 - 6.4e-31 107.6 0.0 3.2e-29 102.0 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO22843.1 - 3.4e-05 22.8 0.0 4.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO22843.1 - 0.00055 19.3 0.0 0.00068 19.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO22843.1 - 0.0047 16.3 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO22843.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO22843.1 - 0.15 12.0 0.1 0.79 9.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO22844.1 - 9e-34 117.0 0.0 1.1e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22844.1 - 1.1e-30 106.8 0.0 1.2e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO22844.1 - 7.5e-06 25.0 0.0 9.5e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO22844.1 - 0.0011 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO22844.1 - 0.0043 16.4 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO22844.1 - 0.0082 15.1 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO22844.1 - 0.023 14.6 0.2 0.072 13.0 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KDO22844.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 KDO22845.1 - 0.002 17.5 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO22845.1 - 0.0059 16.0 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KDO22845.1 - 0.033 13.8 0.1 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Arm PF00514.23 KDO22848.1 - 1.1e-05 25.3 1.7 3.6 7.8 0.0 5.4 4 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat zf-RVT PF13966.6 KDO22848.1 - 0.0032 18.1 0.3 0.0061 17.2 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase EGF_2 PF07974.13 KDO22849.1 - 8.1e-25 86.9 112.5 5e-06 26.8 5.3 9.6 10 0 0 10 10 10 7 EGF-like domain EGF PF00008.27 KDO22849.1 - 1.1e-06 28.9 94.6 9.9e-05 22.6 3.3 9.8 10 0 0 10 10 10 5 EGF-like domain Laminin_EGF PF00053.24 KDO22849.1 - 4.7e-05 23.4 87.2 0.29 11.3 10.9 8.1 7 1 0 7 7 7 7 Laminin EGF domain PAN_1 PF00024.26 KDO22850.1 - 4.6e-17 61.7 24.2 1.5e-06 28.0 2.4 3.5 3 0 0 3 3 3 3 PAN domain Tyrosinase PF00264.20 KDO22850.1 - 4.3e-16 59.9 5.3 5.1e-09 36.7 1.0 2.5 1 1 0 2 2 2 2 Common central domain of tyrosinase PAN_4 PF14295.6 KDO22850.1 - 3.7e-13 49.2 39.7 2.2e-06 27.4 6.5 4.1 4 0 0 4 4 4 3 PAN domain OmdA PF13376.6 KDO22850.1 - 0.024 14.6 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Myticin-prepro PF10690.9 KDO22850.1 - 6.6 7.0 19.5 0.4 10.9 0.9 3.6 3 0 0 3 3 3 0 Myticin pre-proprotein from the mussel HTH_OrfB_IS605 PF12323.8 KDO22850.1 - 7.5 6.1 7.9 12 5.5 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4050 PF13259.6 KDO22854.1 - 0.15 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Rif1_N PF12231.8 KDO22855.1 - 1.2e-22 80.5 0.5 2.6e-22 79.3 0.2 1.7 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Hairy_orange PF07527.13 KDO22855.1 - 0.27 11.5 1.5 22 5.4 0.0 3.2 2 0 0 2 2 2 0 Hairy Orange Ras PF00071.22 KDO22856.1 - 3.4e-41 140.5 0.0 4.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO22856.1 - 3.5e-25 88.6 0.0 4.9e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO22856.1 - 1.3e-09 37.8 0.0 1.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO22856.1 - 0.00046 19.6 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO22856.1 - 0.0079 16.1 0.0 3.6 7.5 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO22856.1 - 0.038 14.1 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4428 PF14471.6 KDO22856.1 - 0.08 12.9 1.8 4 7.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF3716 PF12511.8 KDO22857.1 - 0.027 14.5 30.2 0.54 10.3 1.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3716) RecQ_Zn_bind PF16124.5 KDO22857.1 - 0.032 14.9 17.0 5.4 7.8 0.7 4.2 4 0 0 4 4 4 0 RecQ zinc-binding zf-CXXC PF02008.20 KDO22857.1 - 0.61 10.1 32.3 2.4 8.2 1.5 4.5 4 0 0 4 4 4 0 CXXC zinc finger domain Pkinase PF00069.25 KDO22858.1 - 2.3e-68 230.5 0.0 2.5e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22858.1 - 5.8e-29 101.1 0.0 7.2e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO22858.1 - 4.8e-06 26.1 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO22858.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO22858.1 - 0.016 14.2 0.0 0.038 12.9 0.0 1.6 1 1 1 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KDO22858.1 - 0.21 11.2 0.1 0.41 10.2 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GCP_N_terminal PF17681.1 KDO22859.1 - 7.4e-33 114.5 0.0 1.3e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KDO22859.1 - 1.1e-17 64.5 9.2 9.2e-14 51.6 6.4 3.7 3 1 0 3 3 3 2 Gamma tubulin complex component C-terminal DUF832 PF05734.11 KDO22859.1 - 0.12 11.8 0.5 0.21 11.0 0.5 1.3 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) DUF846 PF05832.12 KDO22860.1 - 1.6e-55 187.0 10.1 1.9e-55 186.7 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 KDO22860.1 - 0.039 14.2 8.3 0.72 10.2 0.8 2.2 2 0 0 2 2 2 0 YwiC-like protein UPF0014 PF03649.13 KDO22860.1 - 0.24 10.7 8.7 0.14 11.5 0.9 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) DUF3446 PF11928.8 KDO22860.1 - 8 6.8 8.9 2.4 8.5 3.9 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain TLD PF07534.16 KDO22861.1 - 5.4e-14 52.6 0.0 7.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 KDO22861.1 - 2.1e-07 30.8 0.0 8.2e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 KDO22863.1 - 3.4e-12 46.7 6.9 0.00025 21.8 0.3 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO22863.1 - 7.7e-09 35.7 0.1 0.35 11.2 0.0 5.2 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KDO22863.1 - 0.0051 14.9 0.0 0.83 7.6 0.0 2.3 2 0 0 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 KDO22863.1 - 0.042 12.8 0.0 0.36 9.8 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_17 PF13207.6 KDO22863.1 - 4.3 7.7 6.1 3.3 8.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain KIAA1430 PF13879.6 KDO22864.1 - 1.1e-18 67.9 0.5 1.1e-18 67.9 0.5 2.5 1 1 1 2 2 2 2 KIAA1430 homologue Tctex-1 PF03645.13 KDO22865.1 - 1.8e-26 92.4 0.3 2.2e-26 92.1 0.3 1.1 1 0 0 1 1 1 1 Tctex-1 family LPD29 PF18847.1 KDO22865.1 - 0.017 16.0 0.0 0.073 14.0 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 29 DUF1351 PF07083.11 KDO22865.1 - 0.047 13.4 0.1 0.06 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) GLE1 PF07817.13 KDO22867.1 - 5.7e-38 130.5 1.6 9e-31 107.0 0.0 2.5 1 1 1 2 2 2 2 GLE1-like protein CxC2 PF18803.1 KDO22867.1 - 0.16 12.2 1.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases Methyltransf_25 PF13649.6 KDO22868.1 - 1.8e-10 41.4 0.0 3.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO22868.1 - 1.6e-09 37.6 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO22868.1 - 7.3e-08 33.0 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 KDO22868.1 - 7.1e-07 29.3 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain MTS PF05175.14 KDO22868.1 - 3.2e-06 26.8 0.0 3e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KDO22868.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KDO22868.1 - 7.1e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KDO22868.1 - 0.00051 20.0 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KDO22868.1 - 0.0031 16.5 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.16 KDO22868.1 - 0.0044 16.9 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 KDO22868.1 - 0.0059 16.4 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO22868.1 - 0.0063 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO22868.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ribosomal_S27e PF01667.17 KDO22869.1 - 8.4e-29 99.1 6.0 1e-28 98.8 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KDO22869.1 - 0.029 14.8 1.1 0.092 13.2 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-CSL PF05207.13 KDO22869.1 - 0.15 11.8 3.0 0.31 10.8 3.0 1.6 1 1 0 1 1 1 0 CSL zinc finger Adaptin_N PF01602.20 KDO22870.1 - 0.06 11.9 0.0 0.097 11.2 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region RIB43A PF05914.12 KDO22871.1 - 1.5e-58 198.3 60.9 1.7e-58 198.2 60.9 1.0 1 0 0 1 1 1 1 RIB43A AAA_2 PF07724.14 KDO22872.1 - 1.2e-44 152.4 0.0 1.7e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KDO22872.1 - 5e-15 56.1 0.0 8.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KDO22872.1 - 3.4e-10 39.8 0.0 6.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 KDO22872.1 - 1.3e-05 25.5 0.2 9.9e-05 22.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 KDO22872.1 - 4.7e-05 22.6 0.3 0.00019 20.6 0.1 1.9 2 0 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 KDO22872.1 - 0.00011 22.3 0.1 0.00059 19.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO22872.1 - 0.00026 20.8 0.1 0.0029 17.4 0.1 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KDO22872.1 - 0.00027 20.7 0.1 0.005 16.6 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KDO22872.1 - 0.0004 20.5 0.0 0.0014 18.8 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KDO22872.1 - 0.0011 18.5 0.1 0.024 14.0 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KDO22872.1 - 0.0033 16.9 0.0 0.0094 15.5 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 KDO22872.1 - 0.0052 15.9 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KDO22872.1 - 0.0076 16.0 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KDO22872.1 - 0.0078 16.6 0.1 0.042 14.2 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KDO22872.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO22872.1 - 0.023 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KDO22872.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO22872.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 KDO22872.1 - 0.049 13.0 0.2 0.097 12.1 0.2 1.4 1 0 0 1 1 1 0 Isopentenyl transferase ABC_tran PF00005.27 KDO22872.1 - 0.054 14.0 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KDO22872.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KDO22872.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KDO22872.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 KDO22872.1 - 0.15 11.8 0.3 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase UPF0016 PF01169.19 KDO22873.1 - 4.9e-41 138.9 22.0 5.2e-22 78.0 6.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 EF-hand_5 PF13202.6 KDO22873.1 - 0.0042 16.5 0.4 0.0096 15.4 0.4 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO22873.1 - 0.0083 16.0 0.3 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KDO22873.1 - 0.017 14.7 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 EF hand DUF3995 PF13160.6 KDO22873.1 - 3 8.2 10.2 9.4 6.6 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Hexapep_loop PF18776.1 KDO22874.1 - 0.02 14.5 0.8 0.67 9.6 0.1 2.6 2 0 0 2 2 2 0 Hexapeptide repeat including loop Lectin_leg-like PF03388.13 KDO22875.1 - 5.2e-27 94.7 0.2 6.1e-19 68.3 0.0 2.3 1 1 1 2 2 2 2 Legume-like lectin family DUF4533 PF15047.6 KDO22875.1 - 0.048 13.2 0.2 0.082 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DCB PF16213.5 KDO22875.1 - 0.13 11.9 0.9 0.21 11.2 0.9 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 TMF_DNA_bd PF12329.8 KDO22875.1 - 0.16 12.0 2.6 0.56 10.2 2.6 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TRAF_BIRC3_bd PF16673.5 KDO22875.1 - 0.19 11.6 2.1 2.2 8.1 0.7 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Baculo_PEP_C PF04513.12 KDO22875.1 - 0.21 11.6 1.5 0.37 10.8 1.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bact_lectin PF18483.1 KDO22875.1 - 0.24 11.4 4.8 7.3 6.6 4.0 2.6 1 1 1 2 2 2 0 Bacterial lectin Lectin_leg-like PF03388.13 KDO22876.1 - 4.9e-33 114.4 0.0 7.8e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KDO22876.1 - 3.8e-12 46.6 0.6 7.1e-12 45.8 0.6 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KDO22876.1 - 0.00064 19.3 0.0 0.0021 17.6 0.0 1.8 1 1 0 1 1 1 1 Legume lectin domain MID_MedPIWI PF18296.1 KDO22877.1 - 1.3e-05 25.1 0.0 0.0055 16.5 0.0 2.5 1 1 1 2 2 2 2 MID domain of medPIWI MTHFR PF02219.17 KDO22878.1 - 4.7e-117 390.4 0.0 7e-117 389.8 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1387 PF07139.11 KDO22880.1 - 8.9 5.9 6.7 19 4.8 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Stap_Strp_tox_C PF02876.17 KDO22881.1 - 0.014 15.7 0.2 0.026 14.8 0.2 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Ribosomal_60s PF00428.19 KDO22882.1 - 2.7 8.7 7.5 0.67 10.6 0.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein ThiF PF00899.21 KDO22883.1 - 3e-104 347.7 0.0 8.1e-70 234.9 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KDO22883.1 - 1.9e-70 237.7 0.0 3.4e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KDO22883.1 - 1.5e-21 76.3 0.1 2.7e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KDO22883.1 - 4.2e-19 68.5 0.0 1.1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 KDO22883.1 - 2.4e-18 66.6 0.0 4.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain Myb_DNA-bind_4 PF13837.6 KDO22885.1 - 0.0067 16.8 0.3 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Mif2_N PF15624.6 KDO22885.1 - 8.6 7.1 13.4 2.3 8.9 8.4 2.2 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal PQQ_3 PF13570.6 KDO22886.1 - 0.47 11.0 2.9 22 5.7 1.6 3.3 2 1 0 2 2 2 0 PQQ-like domain PspB PF06667.12 KDO22890.1 - 0.11 12.6 0.5 0.26 11.4 0.5 1.6 1 0 0 1 1 1 0 Phage shock protein B Ter PF05472.11 KDO22894.1 - 0.044 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) LRR_6 PF13516.6 KDO22895.1 - 0.02 14.9 7.2 14 6.0 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat OsmC PF02566.19 KDO22896.1 - 0.2 12.2 2.1 13 6.3 0.0 3.1 2 1 0 2 2 2 0 OsmC-like protein Glyco_hydro_6 PF01341.17 KDO22898.1 - 1.2e-47 163.2 2.3 2.4e-47 162.1 2.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 TMEM154 PF15102.6 KDO22898.1 - 0.043 13.7 10.2 0.15 11.9 10.2 1.8 1 1 0 1 1 1 0 TMEM154 protein family SOG2 PF10428.9 KDO22898.1 - 0.35 10.0 9.3 0.51 9.5 9.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1180 PF06679.12 KDO22898.1 - 8.3 6.8 16.1 1 9.8 11.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Glyco_hydro_6 PF01341.17 KDO22899.1 - 5.2e-47 161.1 7.1 9.4e-47 160.2 7.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 DUF4207 PF13904.6 KDO22900.1 - 1.1 8.9 28.8 1.7 8.3 28.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Pro-kuma_activ PF09286.11 KDO22901.1 - 5e-13 49.6 0.0 1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KDO22901.1 - 2.8e-06 26.8 0.8 4.4e-06 26.2 0.8 1.2 1 0 0 1 1 1 1 Subtilase family IRK_C PF17655.1 KDO22902.1 - 0.0013 18.3 0.0 0.0015 18.1 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain START PF01852.19 KDO22904.1 - 8.8e-06 25.3 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO22904.1 - 0.0007 19.7 15.1 0.0007 19.7 15.1 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO22904.1 - 0.21 11.8 13.9 0.27 11.4 12.6 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger Topo_C_assoc PF14370.6 KDO22904.1 - 0.39 10.7 1.0 0.86 9.6 1.0 1.5 1 0 0 1 1 1 0 C-terminal topoisomerase domain FYVE PF01363.21 KDO22905.1 - 0.00095 19.3 12.7 0.0034 17.5 12.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO22905.1 - 0.0014 18.8 9.1 0.0032 17.7 9.1 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger SH3-RhoG_link PF16609.5 KDO22906.1 - 0.0012 18.7 0.2 0.0013 18.5 0.2 1.1 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region FYVE PF01363.21 KDO22908.1 - 6.9e-08 32.5 11.1 1.6e-07 31.3 11.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger zinc_ribbon_5 PF13719.6 KDO22908.1 - 0.00074 19.2 4.7 0.036 13.8 5.6 2.8 1 1 1 2 2 2 1 zinc-ribbon domain FYVE_2 PF02318.16 KDO22908.1 - 0.037 14.2 9.0 0.084 13.1 9.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KDO22909.1 - 2.4e-10 40.4 12.5 5.7e-10 39.2 12.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO22909.1 - 0.0019 18.4 5.9 0.02 15.1 7.7 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger WD40 PF00400.32 KDO22910.1 - 0.0024 18.6 4.9 2.9 8.9 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat VIT1 PF01988.19 KDO22910.1 - 3.1 7.6 6.3 9 6.1 6.3 1.7 1 0 0 1 1 1 0 VIT family Myosin_head PF00063.21 KDO22911.1 - 9.3e-198 658.6 0.0 1.9e-197 657.6 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KDO22911.1 - 4e-07 29.3 16.2 0.0058 16.3 0.3 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Zeta_toxin PF06414.12 KDO22911.1 - 0.0057 16.0 0.0 0.018 14.4 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KDO22911.1 - 0.013 15.8 3.5 0.033 14.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KDO22911.1 - 0.097 13.0 1.1 0.67 10.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KDO22911.1 - 0.1 12.9 0.1 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fibin PF15819.5 KDO22911.1 - 0.3 10.8 3.7 0.87 9.3 3.7 1.9 1 0 0 1 1 1 0 Fin bud initiation factor homologue DUF87 PF01935.17 KDO22911.1 - 0.43 10.6 0.0 0.43 10.6 0.0 3.1 3 1 0 3 3 3 0 Helicase HerA, central domain GDPD PF03009.17 KDO22912.1 - 5.7e-49 167.2 0.0 7.9e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 KDO22912.1 - 2.9e-15 55.9 0.0 9.6e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 Starch binding domain cNMP_binding PF00027.29 KDO22912.1 - 1.9e-11 43.9 0.0 4.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain F5_F8_type_C PF00754.25 KDO22912.1 - 0.00032 20.8 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 F5/8 type C domain DUF4429 PF14472.6 KDO22912.1 - 0.12 13.0 0.1 0.38 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) Ras PF00071.22 KDO22913.1 - 1.4e-53 180.8 0.1 1.8e-53 180.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO22913.1 - 2.6e-29 101.9 0.0 4.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO22913.1 - 3.6e-15 55.9 0.0 4.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO22913.1 - 9.5e-05 22.0 0.1 0.00035 20.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KDO22913.1 - 0.0001 22.3 0.1 0.045 13.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO22913.1 - 0.00052 20.1 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO22913.1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KDO22913.1 - 0.00089 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KDO22913.1 - 0.0025 17.3 0.1 0.007 15.9 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KDO22913.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KDO22913.1 - 0.0089 15.8 0.0 0.07 12.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.18 KDO22913.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 KDO22913.1 - 0.032 14.6 0.2 0.077 13.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KDO22913.1 - 0.14 12.1 0.2 0.34 10.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KDO22913.1 - 0.18 11.7 0.3 0.45 10.4 0.3 1.9 1 1 0 1 1 1 0 NACHT domain Frag1 PF10277.9 KDO22914.1 - 8.1e-14 51.7 18.9 1.2e-13 51.1 18.9 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2298 PF10060.9 KDO22914.1 - 0.00033 19.5 4.7 0.00045 19.1 4.7 1.1 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) Cyt_bd_oxida_II PF02322.15 KDO22914.1 - 0.057 12.8 12.1 0.21 10.9 8.3 2.3 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF4231 PF14015.6 KDO22914.1 - 0.53 10.8 0.0 0.53 10.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) PMT_4TMC PF16192.5 KDO22914.1 - 9 5.8 8.5 6.3 6.3 0.1 2.7 3 1 0 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase Aminotran_5 PF00266.19 KDO22916.1 - 2.8e-71 240.4 6.2 2.6e-69 233.9 6.2 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KDO22916.1 - 1.1e-06 28.2 0.7 1.2e-06 28.0 0.7 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Transglut_core PF01841.19 KDO22916.1 - 0.0084 16.6 0.1 0.021 15.3 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Cys_Met_Meta_PP PF01053.20 KDO22916.1 - 0.012 14.2 0.5 0.027 13.0 0.2 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Mito_carr PF00153.27 KDO22917.1 - 2.6e-62 206.8 3.5 8.5e-20 70.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ELMO_CED12 PF04727.13 KDO22919.1 - 1.6e-23 83.7 0.0 2.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Cellulase PF00150.18 KDO22921.1 - 2.4e-19 69.9 0.0 3.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 KDO22922.1 - 5.1e-39 134.2 0.0 6.1e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22922.1 - 1.3e-35 123.0 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO22922.1 - 0.0034 16.7 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO22922.1 - 0.0085 15.5 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO22922.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Cellulase PF00150.18 KDO22923.1 - 2e-25 89.8 0.0 2.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAP206 PF12018.8 KDO22924.1 - 1.1e-72 244.9 0.0 2e-72 244.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function Pyr_redox_2 PF07992.14 KDO22925.1 - 3.9e-55 187.2 0.3 5.4e-55 186.7 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO22925.1 - 2.7e-31 108.1 0.2 4.2e-31 107.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO22925.1 - 2.9e-20 72.6 1.4 4.2e-16 59.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO22925.1 - 3.9e-12 46.0 0.0 2.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO22925.1 - 6e-08 32.5 1.9 6e-07 29.2 1.9 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KDO22925.1 - 6.6e-05 22.3 2.5 0.0095 15.3 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KDO22925.1 - 0.00032 19.9 0.3 0.00057 19.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KDO22925.1 - 0.00039 19.3 0.7 0.013 14.2 0.7 2.3 2 1 1 3 3 3 1 HI0933-like protein GIDA PF01134.22 KDO22925.1 - 0.0014 17.8 1.8 0.0016 17.6 0.5 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KDO22925.1 - 0.0037 16.9 8.4 0.011 15.3 0.6 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO22925.1 - 0.004 17.4 0.4 0.004 17.4 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KDO22925.1 - 0.0058 16.0 1.1 6.7 6.0 0.0 3.3 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KDO22925.1 - 0.013 14.6 0.0 0.43 9.7 0.0 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KDO22925.1 - 0.029 13.4 0.3 3.3 6.7 0.4 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KDO22925.1 - 0.038 13.9 2.4 0.056 13.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KDO22925.1 - 0.062 12.5 0.5 0.14 11.4 0.5 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KDO22925.1 - 0.081 13.4 0.3 10 6.6 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.6 KDO22925.1 - 0.12 12.8 0.2 4.7 7.7 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 KDO22925.1 - 6.3 5.9 5.9 3.5 6.8 1.1 2.1 2 0 0 2 2 2 0 FAD binding domain PX PF00787.24 KDO22926.1 - 2e-06 27.8 0.1 3.7e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 PX domain Sedlin_N PF04628.13 KDO22926.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF2804 PF10974.8 KDO22927.1 - 1.7e-48 165.9 0.0 2.1e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Cellulase PF00150.18 KDO22928.1 - 3.5e-26 92.3 0.0 4.6e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FA_hydroxylase PF04116.13 KDO22929.1 - 7.2e-17 62.0 17.5 7.2e-17 62.0 17.5 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily AAA_12 PF13087.6 KDO22931.1 - 4.7e-50 170.0 0.0 7e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KDO22931.1 - 9.5e-27 94.4 0.5 9.2e-14 51.8 0.1 2.8 2 1 1 3 3 3 2 AAA domain Dna2 PF08696.11 KDO22931.1 - 7.2e-23 81.5 0.1 1.1e-22 80.9 0.1 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.6 KDO22931.1 - 5.4e-14 52.3 0.0 2.7e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KDO22931.1 - 1.7e-11 44.6 0.2 5.8e-11 42.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KDO22931.1 - 1.1e-06 28.6 0.7 0.2 11.3 0.0 3.9 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KDO22931.1 - 8.1e-05 22.6 0.0 0.00044 20.2 0.0 2.2 2 1 0 2 2 2 1 Helicase Cas_Cas4 PF01930.17 KDO22931.1 - 0.00052 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 UvrD_C_2 PF13538.6 KDO22931.1 - 0.00078 19.2 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KDO22931.1 - 0.0058 16.2 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KDO22931.1 - 0.087 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NADH-G_4Fe-4S_3 PF10588.9 KDO22931.1 - 0.095 12.3 0.8 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region AAA_16 PF13191.6 KDO22931.1 - 0.11 12.9 0.1 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PAC1 PF16094.5 KDO22932.1 - 7.3e-07 28.6 0.0 2e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 WD40 PF00400.32 KDO22933.1 - 3.9e-10 40.2 0.7 0.00016 22.4 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO22933.1 - 7.5e-09 35.8 0.0 0.18 12.1 0.0 5.1 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KDO22933.1 - 0.0011 18.6 0.8 0.23 11.0 0.1 2.5 1 1 0 2 2 2 2 PQQ-like domain DUF2357 PF09823.9 KDO22933.1 - 0.012 14.9 0.3 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) YabA PF06156.13 KDO22933.1 - 0.023 15.3 3.8 0.029 15.0 2.5 1.9 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 KDO22933.1 - 0.054 14.4 4.0 0.15 13.0 4.0 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 KDO22933.1 - 0.19 11.8 2.6 0.42 10.6 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ArfGap PF01412.18 KDO22934.1 - 7.5e-16 58.3 2.1 1e-15 57.8 2.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pol_alpha_B_N PF08418.10 KDO22934.1 - 0.0051 16.8 0.1 0.0087 16.0 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Spt4 PF06093.13 KDO22934.1 - 0.031 14.4 1.2 0.061 13.4 1.2 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger zf-B_box PF00643.24 KDO22934.1 - 1.5 9.0 7.1 3 8.1 7.1 1.5 1 1 0 1 1 1 0 B-box zinc finger SnoaL_2 PF12680.7 KDO22935.1 - 1.5e-05 25.6 0.0 2.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 KDO22935.1 - 0.054 13.6 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain RAP PF08373.10 KDO22936.1 - 3.5e-13 49.4 0.0 7.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 RAP domain RIG-I_C-RD PF11648.8 KDO22936.1 - 0.00047 20.4 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I zinc_ribbon_12 PF11331.8 KDO22936.1 - 0.0033 17.2 0.9 1 9.2 0.0 2.5 2 0 0 2 2 2 2 Probable zinc-ribbon domain BTB_2 PF02214.22 KDO22937.1 - 2.4e-07 31.0 0.0 5.4e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain PX PF00787.24 KDO22938.1 - 9.7e-10 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PX domain RNA_pol_3_Rpc31 PF11705.8 KDO22938.1 - 0.13 12.5 2.7 0.19 11.9 2.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SQHop_cyclase_C PF13243.6 KDO22939.1 - 7.1e-56 189.6 4.6 6.9e-49 166.7 1.7 2.3 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KDO22939.1 - 4.2e-50 170.5 1.1 2.1e-44 151.8 0.0 4.7 4 2 2 6 6 6 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KDO22939.1 - 1.1e-35 121.0 7.4 3.7e-08 33.0 0.0 6.9 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KDO22939.1 - 0.0002 20.8 0.2 1.5 8.1 0.0 4.4 5 0 0 5 5 5 2 Pectic acid lyase TED_complement PF07678.14 KDO22939.1 - 0.00029 20.0 0.0 0.13 11.2 0.0 3.5 2 1 0 3 3 3 1 A-macroglobulin TED domain Ank_2 PF12796.7 KDO22940.1 - 4.1e-21 75.4 15.6 1.8e-07 31.6 1.5 6.6 4 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22940.1 - 7.8e-19 67.8 23.4 2.4e-06 28.0 0.4 8.8 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO22940.1 - 8.8e-11 41.8 20.8 0.18 12.2 0.1 11.0 7 2 5 12 12 12 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22940.1 - 5.4e-06 26.4 13.2 5 8.0 0.1 9.5 9 2 2 11 11 11 2 Ankyrin repeat DUF249 PF03158.13 KDO22940.1 - 0.051 13.3 0.5 7.5 6.2 0.0 3.2 3 0 0 3 3 3 0 Multigene family 530 protein Ank PF00023.30 KDO22940.1 - 2.8 8.5 14.0 45 4.7 0.2 6.5 4 3 1 5 5 5 0 Ankyrin repeat Carb_anhydrase PF00194.21 KDO22941.1 - 2.3e-34 119.1 0.1 4.7e-34 118.1 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Bac_GH3_C PF18034.1 KDO22943.1 - 0.13 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Kazal_1 PF00050.21 KDO22944.1 - 1.7e-26 91.9 29.9 1.6e-10 40.8 3.6 3.2 1 1 2 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KDO22944.1 - 3.5e-26 91.1 32.2 2e-08 34.2 5.0 3.2 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain PT PF04886.12 KDO22944.1 - 1.3 8.7 21.6 9.8 5.8 21.6 2.3 1 1 0 1 1 1 0 PT repeat MAGE_N PF12440.8 KDO22944.1 - 9.5 7.0 10.0 80 4.0 8.5 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal FHA PF00498.26 KDO22945.1 - 2e-18 66.5 0.0 3.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO22945.1 - 3.1e-08 33.8 0.0 1.2e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MscS_porin PF12795.7 KDO22945.1 - 0.004 16.7 29.0 0.19 11.2 11.5 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain DUF1192 PF06698.11 KDO22945.1 - 0.029 14.4 2.7 0.029 14.4 2.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FlxA PF14282.6 KDO22945.1 - 0.2 11.6 16.9 4.8 7.2 13.0 2.6 2 0 0 2 2 2 0 FlxA-like protein Lectin_N PF03954.14 KDO22945.1 - 0.99 9.2 4.7 15 5.3 0.5 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CCDC-167 PF15188.6 KDO22945.1 - 8.7 6.8 17.5 3.6 8.0 0.9 3.6 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Elicitin PF00964.17 KDO22947.1 - 0.014 15.5 1.5 0.014 15.5 1.5 3.4 3 0 0 3 3 3 0 Elicitin Thiolase_N PF00108.23 KDO22949.1 - 7.6e-100 333.6 0.4 1.3e-99 332.8 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KDO22949.1 - 2.8e-43 146.5 1.0 2.8e-43 146.5 1.0 2.6 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KDO22949.1 - 7.5e-06 25.7 1.5 7.5e-06 25.7 1.5 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KDO22949.1 - 0.0062 16.4 2.3 0.54 10.1 0.1 3.3 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Nebulin PF00880.18 KDO22949.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Nebulin repeat Pkinase PF00069.25 KDO22950.1 - 6.4e-36 124.1 0.0 7.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22950.1 - 5.8e-32 111.0 0.0 7.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO22950.1 - 7.5e-05 21.7 0.0 8.8e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO22950.1 - 0.0087 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO22950.1 - 0.056 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPRY PF00622.28 KDO22951.1 - 1.6e-05 25.0 0.0 5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 SPRY domain SDF PF00375.18 KDO22952.1 - 3.9e-43 147.9 24.9 2.2e-42 145.5 24.9 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO22953.1 - 8.1e-10 38.3 0.3 1e-09 37.9 0.3 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family YtxH PF12732.7 KDO22953.1 - 0.02 15.4 0.7 0.044 14.3 0.7 1.5 1 0 0 1 1 1 0 YtxH-like protein FMN_red PF03358.15 KDO22955.1 - 2.5e-28 98.8 0.0 3.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KDO22955.1 - 0.00095 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold UDPG_MGDP_dh_C PF03720.15 KDO22955.1 - 0.056 13.9 0.0 0.092 13.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SBP_bac_6 PF13343.6 KDO22956.1 - 3.3e-08 33.3 0.1 4.6e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Mobilization_B PF17511.2 KDO22958.1 - 0.013 15.8 1.2 0.022 15.1 1.2 1.3 1 0 0 1 1 1 0 Mobilization protein B Peptidase_C69 PF03577.15 KDO22960.1 - 4.3e-45 154.3 0.1 2.2e-44 152.0 0.1 2.0 1 1 0 1 1 1 1 Peptidase family C69 DUF4111 PF13427.6 KDO22960.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Pkinase PF00069.25 KDO22961.1 - 1.4e-74 250.8 0.0 1.6e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22961.1 - 5.9e-33 114.3 0.0 7.4e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO22961.1 - 1.7e-06 27.5 0.8 9.2e-06 25.1 0.6 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO22961.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO22961.1 - 0.00019 20.8 0.0 0.0004 19.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like DUF4265 PF14085.6 KDO22961.1 - 0.0024 17.8 0.0 0.0071 16.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4265) RIO1 PF01163.22 KDO22961.1 - 0.018 14.6 0.2 0.042 13.4 0.2 1.5 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KDO22961.1 - 0.031 13.3 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 KDO22961.1 - 0.055 13.0 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NYD-SP28_assoc PF14775.6 KDO22962.1 - 4.9 7.3 6.0 27 5.0 0.2 2.9 2 1 1 3 3 3 0 Sperm tail C-terminal domain BT1 PF03092.16 KDO22963.1 - 4e-06 25.3 2.5 2.9e-05 22.5 0.5 2.4 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 KDO22963.1 - 0.00014 21.1 17.3 0.00026 20.1 0.8 3.4 3 0 0 3 3 3 3 PUCC protein BT1 PF03092.16 KDO22964.1 - 4.9e-06 25.0 0.3 4.9e-06 25.0 0.3 2.2 2 0 0 2 2 2 1 BT1 family DUF5381 PF17353.2 KDO22964.1 - 6.3 6.5 9.8 0.2 11.4 3.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Glyco_hydro_11 PF00457.17 KDO22965.1 - 2e-74 249.1 15.9 4.6e-74 247.9 15.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_62 PF03664.13 KDO22965.1 - 3.4e-66 223.4 6.4 5.8e-66 222.6 6.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 PT PF04886.12 KDO22965.1 - 8e-06 25.3 4.5 1.8e-05 24.2 4.5 1.5 1 0 0 1 1 1 1 PT repeat Glyco_hydro_62 PF03664.13 KDO22966.1 - 5e-26 91.6 0.2 6.7e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_30 PF02055.16 KDO22966.1 - 0.034 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30 PF02055.16 KDO22967.1 - 8.1e-11 41.5 0.1 1.2e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KDO22967.1 - 0.0085 16.3 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain BT1 PF03092.16 KDO22968.1 - 3.3e-07 28.9 1.4 4.9e-07 28.4 0.3 1.7 2 0 0 2 2 2 1 BT1 family BT1 PF03092.16 KDO22969.1 - 4.8e-08 31.7 6.3 1.2e-07 30.4 0.5 2.9 3 0 0 3 3 3 3 BT1 family BT1 PF03092.16 KDO22970.1 - 0.00038 18.8 2.2 0.00038 18.8 2.2 3.0 3 0 0 3 3 3 2 BT1 family SLATT_4 PF18186.1 KDO22970.1 - 0.15 11.7 0.4 0.44 10.2 0.4 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 MFS_1_like PF12832.7 KDO22970.1 - 0.68 8.7 19.3 0.013 14.4 11.5 2.1 2 1 0 2 2 2 0 MFS_1 like family BT1 PF03092.16 KDO22971.1 - 0.00011 20.6 6.8 0.00065 18.1 0.7 3.0 3 0 0 3 3 3 2 BT1 family PUL PF08324.11 KDO22971.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 PUL domain CMD PF02627.20 KDO22973.1 - 0.00027 20.9 0.1 0.00056 19.9 0.1 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF1635 PF07795.11 KDO22974.1 - 0.0015 18.5 2.9 0.0018 18.2 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) DUF4164 PF13747.6 KDO22974.1 - 0.013 15.8 10.6 0.013 15.8 10.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 KDO22974.1 - 0.045 14.1 0.7 0.045 14.1 0.7 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Phage_GPO PF05929.11 KDO22974.1 - 0.056 13.1 8.6 0.092 12.3 8.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SKA1 PF07160.12 KDO22974.1 - 0.074 12.9 7.1 0.12 12.2 7.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CdvA PF18822.1 KDO22974.1 - 0.089 12.6 11.3 0.14 12.0 3.5 2.6 2 1 1 3 3 3 0 CdvA-like coiled-coil domain V_ATPase_I PF01496.19 KDO22974.1 - 0.11 10.5 2.4 0.12 10.2 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAD PF05557.13 KDO22974.1 - 0.12 10.8 12.3 0.044 12.2 9.7 1.5 2 0 0 2 2 2 0 Mitotic checkpoint protein ApoO PF09769.9 KDO22974.1 - 0.38 10.7 3.6 0.47 10.4 1.6 2.1 2 0 0 2 2 2 0 Apolipoprotein O YjbH PF06082.11 KDO22974.1 - 0.42 9.4 3.7 0.48 9.2 3.7 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH HALZ PF02183.18 KDO22974.1 - 0.43 10.8 9.8 7.6 6.8 0.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Trimer_CC PF08954.11 KDO22974.1 - 0.74 9.4 0.1 0.74 9.4 0.1 3.6 3 1 1 4 4 3 0 Trimerisation motif FUSC PF04632.12 KDO22974.1 - 0.97 7.9 7.7 0.16 10.4 4.6 1.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family MRP-S26 PF14943.6 KDO22974.1 - 1.2 9.1 8.2 3.4 7.5 8.2 1.9 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Fungal_TACC PF12709.7 KDO22974.1 - 1.2 9.7 7.6 3.5 8.1 4.3 2.7 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins SlyX PF04102.12 KDO22974.1 - 1.3 9.7 20.8 6.4 7.5 3.3 3.2 2 1 1 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.9 KDO22974.1 - 1.3 9.2 13.7 0.7 10.1 11.2 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KDO22974.1 - 1.4 9.2 13.5 2.3 8.6 13.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 KDO22974.1 - 1.5 7.9 8.1 2.8 6.9 8.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KDO22974.1 - 1.5 8.6 15.9 32 4.4 11.3 3.3 2 1 1 3 3 3 0 Septum formation initiator EspB_PE PF18625.1 KDO22974.1 - 1.8 9.1 12.6 6.3 7.3 6.7 3.4 3 1 0 3 3 3 0 ESX-1 secreted protein B PE domain YabA PF06156.13 KDO22974.1 - 2 9.1 11.1 50 4.6 9.7 2.8 2 1 0 2 2 2 0 Initiation control protein YabA Flg_hook PF02120.16 KDO22974.1 - 2.7 7.9 17.5 7 6.6 3.7 3.3 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Prominin PF05478.11 KDO22974.1 - 3.7 5.4 9.0 5.1 4.9 9.0 1.1 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 KDO22974.1 - 3.9 8.0 12.4 4.9 7.7 1.4 2.6 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 KDO22974.1 - 4.4 5.8 6.4 5.6 5.4 5.5 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A FemAB PF02388.16 KDO22974.1 - 6.7 5.5 7.5 10 4.9 7.5 1.2 1 0 0 1 1 1 0 FemAB family DUF4750 PF15938.5 KDO22975.1 - 4e-18 64.8 1.4 5.5e-18 64.4 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) NeA_P2 PF12312.8 KDO22975.1 - 0.093 12.2 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein LapA_dom PF06305.11 KDO22975.1 - 0.37 10.6 2.2 0.61 9.9 2.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain WW PF00397.26 KDO22976.1 - 1.6e-05 24.9 0.2 2.5e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.7 KDO22978.1 - 0.14 12.8 0.3 0.33 11.6 0.1 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO22979.1 - 5.3e-12 46.0 3.0 6.5e-05 23.4 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO22979.1 - 1.2e-10 41.9 0.3 5.6e-08 33.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO22979.1 - 3.6e-07 30.3 0.4 0.46 10.9 0.0 4.4 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO22979.1 - 5.8e-05 23.2 0.0 34 5.5 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KDO22979.1 - 0.076 13.5 0.6 47 4.7 0.4 3.7 1 1 1 2 2 2 0 Ankyrin repeat B12D PF06522.11 KDO22980.1 - 4e-11 42.5 0.0 5.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 KDO22981.1 - 9.3e-11 41.4 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MatE PF01554.18 KDO22982.1 - 1.1e-28 99.9 41.0 1.5e-16 60.4 14.5 2.8 3 0 0 3 3 3 2 MatE Evr1_Alr PF04777.13 KDO22983.1 - 4.2e-15 56.0 2.6 5.3e-15 55.7 1.4 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KDO22983.1 - 2.5e-14 53.1 0.0 5.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO22983.1 - 0.0085 16.5 0.1 0.075 13.5 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KDO22983.1 - 0.097 13.0 0.0 0.55 10.6 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KDO22983.1 - 0.11 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin FAD_SOX PF18371.1 KDO22983.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Pkinase_Tyr PF07714.17 KDO22985.1 - 4.4e-48 163.8 0.0 5.8e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO22985.1 - 1.3e-47 162.4 0.0 1.9e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RCR PF12273.8 KDO22985.1 - 0.049 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red APH PF01636.23 KDO22985.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO22985.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KDO22985.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4106 PF13388.6 KDO22985.1 - 0.31 10.2 1.0 0.61 9.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SKG6 PF08693.10 KDO22985.1 - 0.36 10.3 1.5 0.72 9.3 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_L17 PF01196.19 KDO22987.1 - 4.1e-35 120.6 0.5 5.2e-35 120.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Yippee-Mis18 PF03226.14 KDO22988.1 - 1.5e-13 50.9 0.0 2.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LepB_GAP_N PF18172.1 KDO22988.1 - 0.004 17.1 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 LepB GAP domain N-terminal subdomain ASD2 PF08687.11 KDO22988.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GTP_cyclohydro2 PF00925.20 KDO22992.1 - 8.7e-55 184.7 0.0 1.4e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Pkinase PF00069.25 KDO22992.1 - 1.7e-46 158.8 0.0 2.4e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO22992.1 - 5.4e-27 94.7 0.0 7.9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO22992.1 - 0.0004 19.5 0.3 0.0063 15.5 0.3 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO22992.1 - 0.011 15.7 0.9 0.021 14.7 0.7 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO22992.1 - 0.033 13.5 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KDO22992.1 - 0.063 12.3 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.14 KDO22992.1 - 0.081 12.3 0.2 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDUFA12 PF05071.16 KDO22993.1 - 9.2e-17 61.7 4.9 1.5e-16 61.0 4.6 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF935 PF06074.12 KDO22994.1 - 5.9 5.5 14.9 20 3.7 14.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF935) DUF872 PF05915.12 KDO22995.1 - 7e-15 55.2 0.0 7.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) YrhK PF14145.6 KDO22995.1 - 0.0049 16.7 6.5 0.041 13.8 2.0 1.5 1 1 1 2 2 2 2 YrhK-like protein DUF2721 PF11026.8 KDO22995.1 - 0.091 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF872 PF05915.12 KDO22996.1 - 1e-12 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Yos1 PF08571.10 KDO22997.1 - 1e-21 77.0 0.6 1.1e-21 76.8 0.6 1.0 1 0 0 1 1 1 1 Yos1-like KIX_2 PF16987.5 KDO23000.1 - 2e-10 40.5 2.7 2e-10 40.5 2.7 4.5 5 1 0 5 5 5 1 KIX domain HSF_DNA-bind PF00447.17 KDO23003.1 - 3.3e-23 82.1 0.7 3.3e-23 82.1 0.7 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Med8 PF10232.9 KDO23003.1 - 0.024 14.3 0.2 0.047 13.3 0.2 1.4 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DNA_pol_B_exo2 PF10108.9 KDO23003.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB AIRC PF00731.20 KDO23004.1 - 2.8e-62 208.7 1.8 2.8e-62 208.7 1.8 2.2 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KDO23004.1 - 3.7e-52 176.4 0.0 5.6e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KDO23004.1 - 5.4e-18 64.4 0.0 1.1e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KDO23004.1 - 4e-06 26.5 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KDO23004.1 - 0.0048 16.4 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF1902 PF08972.11 KDO23004.1 - 0.082 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) ECR1_N PF14382.6 KDO23005.1 - 4.9e-17 61.5 0.8 9.5e-17 60.5 0.8 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KDO23005.1 - 4.1e-11 43.0 0.1 1.1e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 KH domain Metal_resist PF13801.6 KDO23005.1 - 0.083 13.1 1.2 0.15 12.3 1.2 1.4 1 0 0 1 1 1 0 Heavy-metal resistance GxGYxYP_C PF14323.6 KDO23005.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain Ank_2 PF12796.7 KDO23006.1 - 7.2e-48 161.1 38.8 2.9e-11 43.8 2.3 7.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23006.1 - 2.6e-41 139.5 20.7 2.7e-08 34.2 0.3 11.4 3 2 10 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 KDO23006.1 - 5e-30 102.6 32.3 0.00013 22.3 0.9 12.1 11 1 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KDO23006.1 - 3.5e-29 100.5 26.6 4.6e-06 26.8 0.1 9.3 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23006.1 - 8.6e-29 96.4 13.4 0.022 15.2 0.1 12.9 13 0 0 13 13 13 7 Ankyrin repeat BAT PF15915.5 KDO23006.1 - 0.019 14.8 1.1 0.057 13.3 1.1 1.8 1 0 0 1 1 1 0 GAF and HTH_10 associated domain CoA_transf_3 PF02515.17 KDO23007.1 - 0.089 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III adh_short PF00106.25 KDO23008.1 - 6.7e-25 87.7 1.0 4.1e-23 81.9 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO23008.1 - 4.9e-19 68.8 1.3 1.8e-17 63.7 1.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO23008.1 - 6.5e-13 49.0 1.5 9.7e-13 48.4 1.5 1.2 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 KDO23008.1 - 0.0022 17.7 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KDO23008.1 - 0.018 14.8 0.7 0.029 14.2 0.7 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 KDO23008.1 - 0.081 12.4 0.5 0.11 11.9 0.5 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KDO23008.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF5300 PF17224.3 KDO23008.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) 3HCDH_N PF02737.18 KDO23008.1 - 0.16 11.8 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAM104 PF15434.6 KDO23009.1 - 0.0076 16.8 2.1 0.014 15.9 2.1 1.4 1 0 0 1 1 1 1 Family 104 WD40 PF00400.32 KDO23011.1 - 3.8e-28 97.2 17.3 7.3e-05 23.5 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23011.1 - 2.7e-07 30.8 0.9 0.02 15.2 0.2 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO23011.1 - 5.4e-06 25.3 3.7 0.037 12.7 0.2 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 CRAL_TRIO PF00650.20 KDO23012.1 - 2.3e-19 69.7 0.0 2.9e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KDO23012.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Pkinase_Tyr PF07714.17 KDO23013.1 - 4e-57 193.4 0.1 1.4e-56 191.7 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KDO23013.1 - 6.1e-49 166.8 0.0 1.1e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ACR_tran PF00873.19 KDO23013.1 - 0.052 11.2 0.2 0.07 10.8 0.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TMEM52 PF14979.6 KDO23013.1 - 0.11 12.4 1.2 0.23 11.4 1.2 1.6 1 1 0 1 1 1 0 Transmembrane 52 DUF4833 PF16117.5 KDO23014.1 - 8.7e-35 119.7 0.0 1e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) Ricin_B_lectin PF00652.22 KDO23015.1 - 1.7e-18 67.1 7.4 5.6e-09 36.3 0.4 3.0 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Trypsin_2 PF13365.6 KDO23015.1 - 6.8e-16 59.5 2.7 1.2e-15 58.7 0.5 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain RicinB_lectin_2 PF14200.6 KDO23015.1 - 1.5e-05 25.6 12.2 0.00058 20.5 1.7 3.7 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Peptidase_S46 PF10459.9 KDO23015.1 - 0.055 12.1 3.6 0.55 8.8 0.3 2.3 2 0 0 2 2 2 0 Peptidase S46 PQQ PF01011.21 KDO23015.1 - 0.078 12.9 0.1 0.62 10.1 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat Ricin_B_lectin PF00652.22 KDO23016.1 - 2.3e-24 86.0 20.0 1.2e-12 48.2 5.5 3.1 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Trypsin_2 PF13365.6 KDO23016.1 - 3.4e-19 70.2 0.4 7.7e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain RicinB_lectin_2 PF14200.6 KDO23016.1 - 1.5e-06 28.8 19.4 0.0039 17.9 1.4 4.8 1 1 4 5 5 5 4 Ricin-type beta-trefoil lectin domain-like Peptidase_S46 PF10459.9 KDO23016.1 - 0.00042 19.1 0.4 0.031 13.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 Fascin PF06268.13 KDO23016.1 - 0.0019 18.4 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 Fascin domain nos_propeller PF18764.1 KDO23016.1 - 0.091 12.7 0.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat DUF2673 PF10880.8 KDO23016.1 - 0.091 12.9 1.6 1.5 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2673) NifU PF01106.17 KDO23016.1 - 1.5 9.1 3.6 2.3 8.4 0.6 2.7 3 0 0 3 3 3 0 NifU-like domain Trypsin_2 PF13365.6 KDO23017.1 - 1.3e-17 65.1 0.2 6.3e-17 62.9 0.3 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Ricin_B_lectin PF00652.22 KDO23017.1 - 2.5e-11 43.9 4.1 1.8e-10 41.2 4.4 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO23017.1 - 1e-06 29.3 0.8 0.007 17.1 0.1 3.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Peptidase_S46 PF10459.9 KDO23017.1 - 0.005 15.6 0.4 0.12 11.0 0.1 2.1 2 0 0 2 2 2 1 Peptidase S46 CDtoxinA PF03498.14 KDO23017.1 - 0.0053 16.4 0.6 0.028 14.0 0.0 2.4 2 1 1 3 3 3 1 Cytolethal distending toxin A/C domain DUF995 PF06191.12 KDO23017.1 - 0.043 13.5 0.2 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Trypsin_2 PF13365.6 KDO23018.1 - 8.1e-18 65.7 2.2 1.6e-17 64.8 0.4 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO23018.1 - 2.5e-11 43.8 1.1 4.2e-11 43.1 1.1 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KDO23018.1 - 3e-06 26.2 1.6 0.04 12.6 0.1 2.5 2 0 0 2 2 2 2 Peptidase S46 AHD PF17793.1 KDO23018.1 - 0.1 12.4 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Trypsin_2 PF13365.6 KDO23019.1 - 4.1e-16 60.2 0.3 8.5e-16 59.2 0.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO23019.1 - 1.5e-06 28.2 3.5 1.5e-06 28.2 3.5 2.4 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 KDO23019.1 - 3.4e-05 22.7 1.5 0.049 12.3 0.1 2.3 3 0 0 3 3 3 2 Peptidase S46 Peptidase_C4 PF00863.19 KDO23019.1 - 0.024 14.0 0.1 0.13 11.6 0.1 2.0 1 1 1 2 2 2 0 Peptidase family C4 Trypsin_2 PF13365.6 KDO23020.1 - 4.3e-17 63.4 0.1 6.8e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO23020.1 - 1.5e-11 44.5 0.8 3.1e-11 43.5 0.8 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KDO23020.1 - 2.5e-05 23.2 2.2 0.034 12.8 0.2 2.3 2 0 0 2 2 2 2 Peptidase S46 eIF-1a PF01176.19 KDO23021.1 - 6.1e-21 74.0 0.2 8.9e-21 73.5 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Cupin_2 PF07883.11 KDO23023.1 - 3.4e-14 52.3 0.0 4.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KDO23023.1 - 5.7e-08 32.7 0.0 7.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KDO23023.1 - 9.7e-06 25.5 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 KDO23023.1 - 0.00014 21.6 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 KDO23023.1 - 0.00017 21.2 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding_2 PF14525.6 KDO23023.1 - 0.0034 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 AraC-binding-like domain DMSP_lyase PF16867.5 KDO23023.1 - 0.0066 16.1 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_3 PF05899.12 KDO23023.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EutQ PF06249.12 KDO23023.1 - 0.024 14.4 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DPBB_1 PF03330.18 KDO23024.1 - 7.1e-07 29.4 0.1 1.4e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KDO23024.1 - 0.0003 20.6 0.2 0.0005 19.9 0.2 1.4 1 0 0 1 1 1 1 Barwin family Phage_Mu_Gp45 PF06890.12 KDO23024.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein DUF3099 PF11298.8 KDO23027.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DUF5065 PF16723.5 KDO23028.1 - 1 9.4 3.5 2.5 8.1 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) Prefoldin PF02996.17 KDO23033.1 - 2.2e-27 95.4 0.2 3.1e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF5082 PF16888.5 KDO23033.1 - 0.00044 20.5 1.1 0.018 15.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 KDO23033.1 - 0.013 16.1 5.0 0.11 13.1 0.2 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_2 PF01920.20 KDO23033.1 - 0.018 15.0 7.9 0.033 14.2 1.5 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF4510 PF14971.6 KDO23033.1 - 0.047 14.0 0.6 1.8 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) ApoO PF09769.9 KDO23033.1 - 0.056 13.4 0.3 13 5.7 0.0 2.9 2 1 1 3 3 3 0 Apolipoprotein O SlyX PF04102.12 KDO23033.1 - 3.2 8.4 5.6 1.6 9.4 0.9 2.2 2 0 0 2 2 2 0 SlyX Rab5ip PF07019.12 KDO23034.1 - 4.9e-14 52.7 9.1 5.8e-14 52.4 9.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Myb_DNA-binding PF00249.31 KDO23035.1 - 2e-08 34.3 0.2 3e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO23035.1 - 0.039 14.2 0.3 0.051 13.8 0.3 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO23036.1 - 1.2e-10 41.4 0.1 1.6e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO23037.1 - 9.3e-09 35.4 0.1 1.4e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Metallophos PF00149.28 KDO23038.1 - 1.3e-10 42.1 0.2 1.9e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO23038.1 - 0.00012 22.4 0.0 0.00087 19.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adaptin_binding PF10199.9 KDO23040.1 - 0.0013 19.3 0.1 0.0018 18.9 0.1 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Diphthami_syn_2 PF01902.17 KDO23041.1 - 9e-27 94.0 0.0 1.1e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase Ank_2 PF12796.7 KDO23042.1 - 2.6e-05 24.7 6.2 0.14 12.7 2.4 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23042.1 - 2.9e-05 24.5 3.3 0.27 11.9 1.6 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF5049 PF16468.5 KDO23042.1 - 0.0037 17.1 0.0 9.4 6.2 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF5049) Ank_3 PF13606.6 KDO23042.1 - 0.0066 16.9 0.6 18 6.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO23042.1 - 0.012 15.9 5.2 2.5 8.5 0.2 3.4 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Daxx PF03344.15 KDO23042.1 - 0.085 12.9 0.1 8.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain SIR2 PF02146.17 KDO23043.1 - 1.1e-45 155.7 0.0 1.9e-45 154.9 0.0 1.4 1 1 0 1 1 1 1 Sir2 family vATP-synt_E PF01991.18 KDO23044.1 - 6e-47 159.6 7.9 7e-47 159.4 7.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Gemini_AL1_M PF08283.11 KDO23045.1 - 0.092 12.8 0.1 3.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Geminivirus rep protein central domain Glyco_trans_1_3 PF13528.6 KDO23045.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 1 Ank_2 PF12796.7 KDO23048.1 - 2.1e-14 53.9 2.0 1e-05 26.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO23048.1 - 2.6e-08 33.9 1.1 0.16 12.5 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO23048.1 - 6.6e-08 33.0 1.0 0.0025 18.4 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23048.1 - 8.2e-07 29.2 0.9 0.039 14.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23048.1 - 9.3e-06 25.6 2.5 1.4 9.8 0.0 4.9 5 1 0 5 5 5 2 Ankyrin repeat DUF3878 PF12994.7 KDO23048.1 - 0.046 13.2 0.5 0.067 12.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) ACBP PF00887.19 KDO23049.1 - 1e-15 57.7 0.1 1.6e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein PRELI PF04707.14 KDO23050.1 - 2e-14 53.7 0.0 3.7e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 PRELI-like family zf-C3HC4 PF00097.25 KDO23051.1 - 3e-11 43.0 8.2 4.6e-11 42.4 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO23051.1 - 2.8e-10 40.4 10.0 4.9e-10 39.6 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO23051.1 - 4e-10 39.4 7.5 6.5e-10 38.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO23051.1 - 5.4e-09 35.9 2.1 5.4e-09 35.9 2.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO23051.1 - 1.1e-08 34.8 8.4 1.8e-08 34.1 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO23051.1 - 1.6e-07 31.2 6.8 2.6e-07 30.5 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO23051.1 - 1.1e-06 28.3 7.2 2.8e-06 27.1 7.2 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO23051.1 - 4.4e-06 26.9 10.2 1.1e-05 25.6 10.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KDO23051.1 - 1.5e-05 25.0 8.3 3.1e-05 24.0 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FecCD PF01032.18 KDO23051.1 - 0.0024 16.9 0.9 0.0031 16.6 0.9 1.1 1 0 0 1 1 1 1 FecCD transport family U-box PF04564.15 KDO23051.1 - 0.0064 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 U-box domain zf-RING_11 PF17123.5 KDO23051.1 - 0.026 14.3 2.5 0.026 14.3 2.5 2.4 2 1 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KDO23051.1 - 0.033 14.2 4.9 0.058 13.4 4.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2070 PF09843.9 KDO23051.1 - 0.14 10.4 0.4 0.18 10.1 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-RING_4 PF14570.6 KDO23051.1 - 0.24 11.2 10.3 0.73 9.7 10.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 KDO23051.1 - 0.44 10.6 3.8 0.8 9.7 3.8 1.4 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KDO23051.1 - 0.68 10.0 5.7 1.8 8.6 5.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon Ras PF00071.22 KDO23052.1 - 1.1e-57 194.1 0.3 1.3e-57 193.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23052.1 - 3.2e-35 121.0 0.1 4.9e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23052.1 - 1.2e-17 63.9 0.4 1.7e-17 63.4 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO23052.1 - 1.9e-06 27.4 0.1 2.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO23052.1 - 2.6e-05 24.3 0.1 5.4e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO23052.1 - 8.2e-05 22.2 0.2 0.0004 20.0 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO23052.1 - 0.00031 20.2 0.1 0.00052 19.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit VirE PF05272.11 KDO23052.1 - 0.0045 16.7 0.2 0.045 13.5 0.1 2.2 2 0 0 2 2 2 1 Virulence-associated protein E AAA_16 PF13191.6 KDO23052.1 - 0.033 14.6 0.0 0.065 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KDO23052.1 - 0.035 14.0 0.3 0.54 10.1 0.1 2.4 1 1 2 3 3 3 0 RsgA GTPase Septin PF00735.18 KDO23052.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KDO23052.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PH PF00169.29 KDO23053.1 - 7.9e-39 132.4 0.0 3.8e-09 37.0 0.0 6.5 4 2 1 5 5 5 5 PH domain PH_8 PF15409.6 KDO23053.1 - 3.9e-15 55.9 0.0 0.022 15.0 0.0 5.2 5 0 0 5 5 5 4 Pleckstrin homology domain PH_11 PF15413.6 KDO23053.1 - 2.9e-11 43.7 0.6 0.57 10.6 0.0 6.0 6 1 0 6 6 6 4 Pleckstrin homology domain PH_3 PF14593.6 KDO23053.1 - 0.00071 19.7 0.0 1.4 9.1 0.0 3.7 3 1 0 4 4 4 1 PH domain Haem_degrading PF03928.14 KDO23053.1 - 0.07 13.2 2.1 0.45 10.6 0.3 2.9 3 0 0 3 3 3 0 Haem-degrading PH_9 PF15410.6 KDO23053.1 - 0.077 13.4 0.0 1.1e+02 3.2 0.0 4.7 6 0 0 6 6 6 0 Pleckstrin homology domain Scs3p PF10261.9 KDO23054.1 - 0.00091 18.8 1.4 0.001 18.7 1.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM MadM PF03818.13 KDO23055.1 - 0.13 12.2 1.7 8.7 6.3 0.2 2.5 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Aldolase_II PF00596.21 KDO23056.1 - 1.3e-16 61.0 0.7 1.9e-16 60.5 0.7 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain UBX PF00789.20 KDO23056.1 - 0.00055 20.1 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain Methyltransf_11 PF08241.12 KDO23057.1 - 0.095 13.4 0.0 4.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain MSC PF09402.10 KDO23060.1 - 2.7e-08 33.7 2.4 1.2e-07 31.5 2.4 2.0 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain TetR_C_6 PF13977.6 KDO23060.1 - 0.0019 18.4 4.2 0.0046 17.2 2.2 2.5 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal Zip PF02535.22 KDO23061.1 - 4.4e-27 95.2 8.2 1.7e-26 93.2 8.2 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 KDO23061.1 - 2.5e-11 43.4 1.2 0.00015 21.5 0.2 2.8 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KDO23061.1 - 2.5e-05 24.3 5.6 0.00021 21.3 2.1 2.9 2 1 0 2 2 2 1 Multicopper oxidase Pkinase PF00069.25 KDO23062.1 - 1.7e-34 119.4 7.6 3.6e-11 42.9 0.1 3.8 4 0 0 4 4 4 3 Protein kinase domain tRNA-synt_His PF13393.6 KDO23062.1 - 1.7e-18 66.9 1.6 2.4e-17 63.2 0.0 2.9 2 1 0 2 2 2 1 Histidyl-tRNA synthetase Pkinase_Tyr PF07714.17 KDO23062.1 - 6.4e-16 58.4 0.0 4.7e-06 26.1 0.0 3.9 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 KDO23062.1 - 7.1e-11 42.1 0.1 7.1e-11 42.1 0.1 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.22 KDO23062.1 - 1.2e-09 38.5 0.0 3.6e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 RWD domain GramPos_pilinBB PF16569.5 KDO23062.1 - 1.4 9.8 3.2 0.87 10.4 0.2 2.1 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain Cwf_Cwc_15 PF04889.12 KDO23062.1 - 2 8.1 28.1 2.1 8.0 5.9 2.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Tetraspanin PF00335.20 KDO23063.1 - 2.6e-12 46.9 6.5 4e-12 46.3 6.5 1.2 1 0 0 1 1 1 1 Tetraspanin family Yip1 PF04893.17 KDO23063.1 - 3.1 7.5 9.2 0.19 11.4 4.0 1.6 2 0 0 2 2 2 0 Yip1 domain Ribosomal_L35Ae PF01247.18 KDO23064.1 - 2.6e-42 142.9 1.2 3e-42 142.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KDO23064.1 - 0.057 13.6 0.0 3 8.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Tetraspanin PF00335.20 KDO23065.1 - 0.0003 20.6 0.0 0.00075 19.3 0.0 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF4381 PF14316.6 KDO23065.1 - 0.055 13.7 0.8 5.3 7.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) RPN6_N PF18055.1 KDO23066.1 - 0.2 12.0 1.2 12 6.3 0.0 2.2 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain DEAD PF00270.29 KDO23067.1 - 3e-45 154.1 0.1 5.8e-45 153.2 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO23067.1 - 7e-27 94.0 0.0 1.9e-24 86.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO23067.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KDO23068.1 - 2.1e-47 161.7 0.0 7.7e-47 159.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23068.1 - 2.1e-22 79.7 0.0 4.1e-22 78.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO23068.1 - 7.1e-07 29.4 1.6 0.0016 18.4 0.1 2.6 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO23068.1 - 2e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO23068.1 - 7.6e-05 21.7 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO23068.1 - 0.00049 19.5 0.0 0.034 13.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 KDO23068.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CorA PF01544.18 KDO23069.1 - 1.7e-08 34.1 6.6 5.8e-08 32.4 6.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EamA PF00892.20 KDO23070.1 - 0.36 11.0 16.2 0.39 10.9 2.4 2.3 2 0 0 2 2 2 0 EamA-like transporter family EamA PF00892.20 KDO23071.1 - 1.2e-23 83.8 37.3 3.2e-14 53.3 15.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 KDO23072.1 - 7e-77 254.1 27.6 8e-19 68.0 0.2 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KDO23072.1 - 1.2e-51 171.0 28.8 3.2e-05 24.2 0.9 10.1 9 1 1 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 KDO23072.1 - 2.9e-48 161.6 12.8 1.5e-09 38.2 0.2 7.3 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23072.1 - 1.5e-47 154.0 9.8 6.2e-05 23.1 0.0 10.2 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 KDO23072.1 - 9.7e-39 130.9 24.3 4.5e-08 33.2 0.6 9.3 2 2 8 10 10 10 10 Ankyrin repeats (many copies) DUF5535 PF17687.1 KDO23072.1 - 0.003 17.7 0.1 17 5.6 0.0 4.8 1 1 4 6 6 6 1 Family of unknown function (DUF5535) VWA_3_C PF18571.1 KDO23072.1 - 0.027 14.3 4.1 36 4.3 0.0 6.1 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain 3HCDH_RFF PF18321.1 KDO23072.1 - 0.074 13.5 1.9 60 4.2 0.1 4.8 4 1 0 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain F420H2_quin_red PF04075.14 KDO23072.1 - 0.15 12.2 0.2 3.6 7.7 0.1 2.7 1 1 1 2 2 2 0 F420H(2)-dependent quinone reductase Ank_2 PF12796.7 KDO23075.1 - 4.5e-35 120.1 4.0 1.8e-13 50.9 0.4 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KDO23075.1 - 4.3e-23 80.7 2.1 3.5e-07 30.4 0.6 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KDO23075.1 - 4.5e-20 71.5 0.7 2.8e-09 37.1 0.2 4.3 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO23075.1 - 8.2e-16 58.2 0.1 2e-07 31.4 0.1 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23075.1 - 2e-15 55.4 0.1 0.00034 20.8 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Mur_ligase PF01225.25 KDO23075.1 - 0.14 12.5 0.1 0.43 10.9 0.1 1.9 2 1 1 3 3 3 0 Mur ligase family, catalytic domain Ank_2 PF12796.7 KDO23076.1 - 5.5e-89 292.9 33.2 5e-17 62.3 0.1 7.2 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KDO23076.1 - 2.6e-70 230.0 43.3 7.1e-06 26.2 0.0 14.1 14 0 0 14 14 14 14 Ankyrin repeat Ank_5 PF13857.6 KDO23076.1 - 3.5e-64 212.0 38.1 7.8e-11 42.0 1.1 11.4 3 3 9 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO23076.1 - 6e-61 202.1 24.6 1.5e-07 31.8 0.1 10.2 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23076.1 - 3.5e-58 186.7 22.7 0.00011 22.3 0.0 14.1 14 0 0 14 14 14 13 Ankyrin repeat Mur_ligase PF01225.25 KDO23076.1 - 0.00057 20.2 1.4 0.51 10.7 0.0 4.3 4 2 0 4 4 4 1 Mur ligase family, catalytic domain DUF3107 PF11305.8 KDO23076.1 - 0.0011 19.2 2.1 10 6.5 0.0 5.8 4 1 2 6 6 6 1 Protein of unknown function (DUF3107) EccE PF11203.8 KDO23076.1 - 0.015 15.6 14.1 0.082 13.2 0.7 4.2 3 1 1 4 4 4 0 Putative type VII ESX secretion system translocon, EccE SCP1201-deam PF14428.6 KDO23076.1 - 0.017 15.0 0.9 10 6.0 0.1 3.6 3 0 0 3 3 3 0 SCP1.201-like deaminase Nitro_FeMo-Co PF02579.17 KDO23076.1 - 0.023 15.0 0.6 62 4.0 0.1 4.1 3 1 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Erythro-docking PF09277.11 KDO23076.1 - 0.051 13.5 13.9 4.3 7.3 0.6 6.6 7 1 1 8 8 8 0 Erythronolide synthase, docking 3HCDH_RFF PF18321.1 KDO23076.1 - 3.4 8.2 14.4 31 5.1 0.0 7.3 8 1 1 9 9 8 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Nterm_IS4 PF13006.7 KDO23076.1 - 4 7.7 6.9 53 4.1 0.0 5.2 5 3 1 6 6 6 0 Insertion element 4 transposase N-terminal Ank_2 PF12796.7 KDO23077.1 - 0.00042 20.9 0.0 0.00055 20.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23077.1 - 0.00045 20.7 0.0 0.00067 20.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23077.1 - 0.0023 18.3 0.0 0.41 11.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat NUDIX PF00293.28 KDO23078.1 - 0.033 14.2 0.3 0.48 10.5 0.3 2.1 1 1 0 1 1 1 0 NUDIX domain Bot1p PF12298.8 KDO23079.1 - 0.005 17.0 1.7 0.016 15.4 1.7 2.0 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 KDO23079.1 - 0.034 14.3 0.1 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Pkinase_Tyr PF07714.17 KDO23080.1 - 5.2e-26 91.5 0.0 8.4e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO23080.1 - 3.1e-20 72.6 0.0 5.1e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_1 PF00561.20 KDO23081.1 - 2.6e-24 86.3 0.0 3.9e-23 82.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO23081.1 - 3.7e-16 59.1 0.3 7.7e-16 58.1 0.3 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO23081.1 - 7.8e-15 56.1 3.5 1e-14 55.7 3.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KDO23081.1 - 0.0044 16.6 0.1 0.29 10.6 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family Thioesterase PF00975.20 KDO23081.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KDO23081.1 - 0.033 14.0 0.3 0.83 9.5 0.3 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KDO23081.1 - 0.066 12.8 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ubiquitin PF00240.23 KDO23082.1 - 0.0014 18.4 0.2 0.0073 16.0 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family CCDC53 PF10152.9 KDO23083.1 - 0.0013 19.1 4.8 0.0032 17.9 4.8 1.7 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex DUF935 PF06074.12 KDO23083.1 - 2.4 6.8 7.9 3.5 6.3 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF935) B56 PF01603.20 KDO23084.1 - 1.5e-15 57.1 0.0 4.9e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) DLH PF01738.18 KDO23084.1 - 0.21 11.1 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family ENTH PF01417.20 KDO23086.1 - 3.2e-15 56.3 0.0 7.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 KDO23086.1 - 8.4e-05 21.7 0.0 0.011 14.7 0.0 2.4 2 1 0 2 2 2 2 ANTH domain HEAT PF02985.22 KDO23086.1 - 0.0014 18.7 0.0 20 5.8 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat SIL1 PF16782.5 KDO23086.1 - 0.14 11.4 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 Aa_trans PF01490.18 KDO23087.1 - 4.5e-20 71.7 29.7 4e-13 48.8 17.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein FYVE PF01363.21 KDO23088.1 - 9.7e-14 51.3 17.4 1.5e-13 50.7 17.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO23088.1 - 0.0033 17.6 11.2 0.0049 17.1 11.2 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger RSN1_7TM PF02714.15 KDO23090.1 - 1.7e-41 142.4 20.2 2.8e-41 141.7 20.2 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KDO23090.1 - 4.4e-23 82.4 4.2 1.9e-16 60.8 0.0 2.2 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KDO23090.1 - 2.6e-19 69.5 0.6 1.7e-18 66.9 0.6 2.4 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport TMEM141 PF15110.6 KDO23090.1 - 0.077 13.6 0.3 2.3 8.9 0.0 2.7 2 0 0 2 2 2 0 TMEM141 protein family DUF751 PF05421.11 KDO23090.1 - 1 10.1 9.9 0.13 13.0 0.4 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF751) ArfGap PF01412.18 KDO23091.1 - 3.5e-27 94.8 0.0 5.9e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PDZ_6 PF17820.1 KDO23091.1 - 7.3e-11 41.7 1.1 6.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO23091.1 - 4.1e-09 36.6 0.7 0.0013 19.1 0.0 2.4 1 1 1 2 2 2 2 PDZ domain PDZ PF00595.24 KDO23091.1 - 8e-08 32.5 0.0 0.0042 17.4 0.1 2.3 2 0 0 2 2 2 2 PDZ domain GreA_GreB PF01272.19 KDO23091.1 - 0.063 13.2 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term zf-C2H2 PF00096.26 KDO23091.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type XAF1_C PF18608.1 KDO23091.1 - 0.48 10.0 2.2 0.76 9.4 0.3 2.2 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain zf_C2HC_14 PF18574.1 KDO23091.1 - 1.4 8.8 4.9 0.19 11.5 0.5 1.8 2 0 0 2 2 2 0 C2HC Zing finger domain FYVE PF01363.21 KDO23092.1 - 3.7e-09 36.6 12.5 8.6e-09 35.4 12.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger PID_2 PF14719.6 KDO23092.1 - 0.053 13.4 1.5 0.087 12.7 1.5 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) V-SNARE PF05008.15 KDO23093.1 - 0.1 13.0 2.3 0.31 11.4 1.8 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CsoS2_M PF12288.8 KDO23093.1 - 0.11 11.9 4.3 0.14 11.6 4.3 1.1 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region IML1 PF12257.8 KDO23094.1 - 5.4e-77 258.7 0.0 7.6e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 PNK3P PF08645.11 KDO23095.1 - 8.2e-48 162.2 0.0 1.3e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KDO23095.1 - 1.1e-13 51.6 0.0 1.3e-06 28.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KDO23095.1 - 0.0022 17.3 0.0 0.21 10.8 0.0 2.8 1 1 2 3 3 3 1 Zeta toxin AAA_16 PF13191.6 KDO23095.1 - 0.012 16.1 0.0 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KDO23095.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KDO23095.1 - 0.051 14.1 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KDO23095.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KDO23095.1 - 0.15 12.3 0.1 0.49 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 KDO23095.1 - 0.2 11.0 0.2 1.7 8.1 0.1 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 HIT PF01230.23 KDO23096.1 - 6e-20 71.8 0.1 1.5e-19 70.5 0.1 1.6 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KDO23096.1 - 4.1e-06 27.3 0.3 1.3e-05 25.6 0.3 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KDO23096.1 - 0.15 11.9 0.0 1.4 8.8 0.1 2.4 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 PX PF00787.24 KDO23097.1 - 4.5e-11 42.7 0.0 7.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 PX domain Tubulin PF00091.25 KDO23098.1 - 2.9e-40 138.6 1.9 4.3e-40 138.0 1.9 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KDO23098.1 - 1.7e-33 114.8 3.2 1.9e-33 114.6 0.9 2.2 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 KDO23098.1 - 5 6.2 10.3 13 4.9 3.9 2.9 1 1 1 2 2 2 0 Tubulin like BRCT PF00533.26 KDO23099.1 - 2.2e-09 37.5 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KDO23099.1 - 5.6e-09 36.3 0.0 7.2e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KDO23099.1 - 2.6e-07 30.5 0.2 3.6e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 KDO23099.1 - 1.7e-06 28.3 0.0 2.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KDO23099.1 - 0.059 13.3 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF4054 PF13262.6 KDO23100.1 - 0.091 12.8 0.1 0.45 10.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4054) DUF5527 PF17665.1 KDO23100.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Ras PF00071.22 KDO23101.1 - 2e-66 222.6 0.9 2.3e-66 222.4 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23101.1 - 7.3e-37 126.2 0.4 1.9e-36 124.9 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23101.1 - 1.1e-17 64.1 0.1 1.3e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KDO23101.1 - 7e-06 25.6 0.1 8.9e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KDO23101.1 - 1e-05 25.5 0.7 0.13 12.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO23101.1 - 1.5e-05 25.0 0.0 4.3e-05 23.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO23101.1 - 2.2e-05 24.0 0.1 2.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KDO23101.1 - 0.00015 21.4 0.4 0.00038 20.1 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KDO23101.1 - 0.002 18.6 0.2 0.29 11.6 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO23101.1 - 0.008 15.7 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_29 PF13555.6 KDO23101.1 - 0.0083 15.9 0.2 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain FeoB_N PF02421.18 KDO23101.1 - 0.01 15.4 0.1 0.072 12.6 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KDO23101.1 - 0.023 14.4 0.1 0.93 9.2 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KDO23101.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO23101.1 - 0.03 14.7 0.0 0.047 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KDO23101.1 - 0.045 14.0 0.0 0.063 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KDO23101.1 - 0.053 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KDO23101.1 - 0.054 14.0 0.1 0.087 13.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KDO23101.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein WD40 PF00400.32 KDO23102.1 - 9.4e-12 45.3 16.2 0.095 13.6 0.3 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23102.1 - 4.2e-07 30.2 0.5 0.1 12.9 0.1 3.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain 4HFCP_synth PF04476.13 KDO23102.1 - 0.063 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 4-HFC-P synthase Kelch_3 PF13415.6 KDO23102.1 - 0.68 10.3 3.1 12 6.3 0.1 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain AAA PF00004.29 KDO23103.1 - 7.6e-18 65.2 0.0 2.1e-17 63.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KDO23103.1 - 2.1e-13 50.4 0.0 4.1e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KDO23103.1 - 2.1e-10 40.9 0.0 5.5e-10 39.5 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 KDO23103.1 - 3.2e-06 27.6 0.0 0.00022 21.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KDO23103.1 - 4.7e-06 26.7 0.0 1.3e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KDO23103.1 - 7.7e-06 26.2 0.0 2.1e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 KDO23103.1 - 1.4e-05 24.9 0.0 6.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KDO23103.1 - 4.2e-05 23.4 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO23103.1 - 9.2e-05 22.7 0.1 0.38 11.0 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 KDO23103.1 - 0.00035 20.5 0.0 0.00065 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KDO23103.1 - 0.00072 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KDO23103.1 - 0.001 18.5 0.0 0.052 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KDO23103.1 - 0.0014 18.7 0.0 0.0037 17.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KDO23103.1 - 0.0059 16.3 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KDO23103.1 - 0.007 16.4 0.1 0.09 12.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KDO23103.1 - 0.0077 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KDO23103.1 - 0.0098 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KDO23103.1 - 0.014 15.8 0.1 0.15 12.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KDO23103.1 - 0.019 14.8 0.1 0.19 11.5 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KDO23103.1 - 0.038 13.7 0.1 0.15 11.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.13 KDO23103.1 - 0.042 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KDO23103.1 - 0.062 13.8 0.0 0.38 11.3 0.0 2.3 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KDO23103.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KDO23103.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KDO23103.1 - 0.097 11.8 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain TIP49 PF06068.13 KDO23103.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 KDO23103.1 - 0.1 11.8 0.0 1.3 8.2 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KDO23103.1 - 0.1 12.0 0.1 5 6.5 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.22 KDO23103.1 - 0.16 12.4 0.0 0.6 10.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Cupin_8 PF13621.6 KDO23104.1 - 6.1e-54 183.4 0.1 7.8e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain GlcNAc PF11397.8 KDO23105.1 - 4.4e-57 194.1 1.5 3.1e-51 174.9 0.3 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) FYVE PF01363.21 KDO23106.1 - 0.01 15.9 14.3 0.021 15.0 14.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 KDO23106.1 - 0.088 13.0 7.0 0.18 12.0 7.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KDO23107.1 - 5.5e-10 39.2 7.2 1.4e-09 37.9 7.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO23107.1 - 0.00026 21.2 5.3 0.00061 20.0 5.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Sigma70_ner PF04546.13 KDO23107.1 - 0.0038 17.2 4.5 0.0099 15.8 4.5 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region C1_2 PF03107.16 KDO23107.1 - 0.021 15.2 4.8 0.021 15.2 4.8 2.3 3 0 0 3 3 3 0 C1 domain C1_1 PF00130.22 KDO23107.1 - 0.092 12.6 3.6 0.23 11.4 3.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.6 KDO23107.1 - 0.21 11.6 8.9 0.45 10.5 8.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-HIT PF04438.16 KDO23107.1 - 0.25 11.2 8.1 0.79 9.7 8.1 1.9 1 0 0 1 1 1 0 HIT zinc finger zf-RING_2 PF13639.6 KDO23107.1 - 1.4 9.4 7.1 3.4 8.1 7.1 1.7 1 0 0 1 1 1 0 Ring finger domain E1_dh PF00676.20 KDO23109.1 - 7.1e-103 343.7 0.1 9.2e-103 343.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KDO23109.1 - 0.0094 15.7 1.7 0.0094 15.7 1.7 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KDO23109.1 - 0.011 14.7 0.2 0.023 13.6 0.0 1.5 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 KDO23109.1 - 0.014 14.6 0.4 0.045 13.0 0.0 1.8 2 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase HlyIII PF03006.20 KDO23110.1 - 3.1e-48 164.4 26.5 7.7e-43 146.8 19.0 2.1 2 0 0 2 2 2 2 Haemolysin-III related Glutaredoxin PF00462.24 KDO23111.1 - 1.1e-18 67.2 0.1 1.5e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KDO23111.1 - 0.00066 20.0 0.0 0.0011 19.3 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 KDO23111.1 - 0.007 16.7 0.0 0.0098 16.3 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 KDO23111.1 - 0.0078 16.5 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 KDO23111.1 - 0.012 16.0 0.1 0.017 15.6 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 KDO23111.1 - 0.048 13.4 0.4 0.31 10.8 0.0 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Prim-Pol PF09250.11 KDO23111.1 - 0.15 12.4 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Glutaredoxin PF00462.24 KDO23112.1 - 1.9e-17 63.2 0.0 2.7e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KDO23112.1 - 0.00017 21.9 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO23112.1 - 0.00018 21.7 0.0 0.00026 21.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 KDO23112.1 - 0.012 15.4 0.1 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 KDO23112.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KDO23112.1 - 0.076 13.5 0.1 0.099 13.1 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_72 PF03198.14 KDO23113.1 - 1.2e-33 116.7 0.1 4.6e-24 85.2 0.0 2.6 1 1 1 2 2 2 2 Glucanosyltransferase rve PF00665.26 KDO23114.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain EMP70 PF02990.16 KDO23115.1 - 1.5e-212 706.9 12.0 2.1e-212 706.4 12.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ACAS_N PF16177.5 KDO23115.1 - 0.1 12.5 0.4 0.27 11.2 0.4 1.7 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus DUF21 PF01595.20 KDO23116.1 - 1.3e-36 125.9 0.6 2.5e-36 125.0 0.6 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO23116.1 - 2.4e-11 43.9 0.9 0.00017 22.0 0.3 2.7 2 0 0 2 2 2 2 CBS domain Arteri_nsp7a PF16749.5 KDO23116.1 - 0.026 14.7 0.4 0.15 12.3 0.4 2.3 1 1 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha cNMP_binding PF00027.29 KDO23116.1 - 0.051 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF21 PF01595.20 KDO23118.1 - 8.3e-27 94.0 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO23118.1 - 1.1e-10 41.8 0.8 0.00043 20.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF21 PF01595.20 KDO23119.1 - 1.2e-34 119.5 1.7 1.8e-34 119.0 1.7 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO23119.1 - 5.3e-07 30.0 0.5 0.0012 19.2 0.0 2.9 2 1 0 2 2 2 2 CBS domain IncD PF17628.2 KDO23119.1 - 1.1 9.1 5.6 0.51 10.1 2.7 1.9 2 1 0 2 2 2 0 Inclusion membrane protein D Glyco_hydro_18 PF00704.28 KDO23120.1 - 1e-73 248.8 0.1 2.2e-73 247.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ricin_B_lectin PF00652.22 KDO23120.1 - 5.4e-26 91.3 9.7 1.4e-13 51.2 0.6 2.7 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO23120.1 - 3.2e-10 40.6 13.1 9.9e-06 26.2 0.8 3.7 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO23120.1 - 0.019 14.6 0.5 6.1 6.4 0.1 2.4 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain NHL PF01436.21 KDO23121.1 - 2.4e-25 87.3 13.9 3e-06 27.0 0.0 6.8 7 0 0 7 7 7 6 NHL repeat GFO_IDH_MocA PF01408.22 KDO23122.1 - 3.4e-19 69.8 0.2 5.5e-19 69.2 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KDO23122.1 - 2.5e-11 43.6 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KDO23122.1 - 1.9e-05 25.3 0.2 3.2e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain LRR_4 PF12799.7 KDO23123.1 - 0.06 13.8 3.5 0.17 12.3 1.1 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO23123.1 - 0.14 11.9 1.2 0.27 11.0 0.2 2.0 2 1 0 2 2 2 0 Leucine rich repeat Abhydrolase_1 PF00561.20 KDO23124.1 - 4e-26 92.2 0.0 4.9e-24 85.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO23124.1 - 2.6e-14 54.4 9.7 4e-14 53.8 9.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO23124.1 - 5.8e-11 42.1 2.2 1.8e-10 40.5 2.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KDO23124.1 - 0.0032 17.2 0.3 0.0093 15.7 0.2 1.8 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 KDO23124.1 - 0.0058 16.8 0.1 0.014 15.5 0.1 1.9 1 1 0 1 1 1 1 Thioesterase domain Esterase_phd PF10503.9 KDO23124.1 - 0.0066 16.0 0.3 0.61 9.5 0.0 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase Ndr PF03096.14 KDO23124.1 - 0.1 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 KDO23125.1 - 1.3e-20 74.2 0.1 2.5e-17 63.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO23125.1 - 9.7e-14 51.2 0.5 1.6e-13 50.5 0.5 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO23125.1 - 4.7e-12 47.0 2.0 6e-12 46.6 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KDO23125.1 - 0.0019 17.8 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KDO23125.1 - 0.012 15.1 1.1 0.79 9.2 0.1 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KDO23125.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 KDO23125.1 - 0.06 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KDO23125.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KDO23126.1 - 4.5e-19 69.1 0.1 1.4e-17 64.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO23126.1 - 5e-13 50.2 3.3 6.4e-13 49.8 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO23126.1 - 2.4e-12 46.7 0.3 3.8e-12 46.0 0.3 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 KDO23126.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF5635 PF18685.1 KDO23127.1 - 1.1 9.2 6.4 0.086 12.8 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5635) SSP160 PF06933.11 KDO23127.1 - 2.1 6.5 10.2 4 5.5 10.2 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 KDO23127.1 - 9.1 4.1 7.0 15 3.4 7.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA PF00004.29 KDO23128.1 - 5.9e-06 26.7 0.1 2.4e-05 24.8 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO23128.1 - 1.1e-05 26.0 0.0 0.00014 22.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KDO23128.1 - 0.0001 21.9 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KDO23128.1 - 0.00063 19.7 0.1 0.39 10.6 0.0 2.5 2 0 0 2 2 2 1 NTPase RRN3 PF05327.11 KDO23128.1 - 0.00068 18.3 9.5 0.00068 18.3 9.5 1.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Rad17 PF03215.15 KDO23128.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KDO23128.1 - 0.002 18.1 0.0 0.0053 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2457 PF10446.9 KDO23128.1 - 0.003 16.8 20.5 0.003 16.8 20.5 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF2457) NACHT PF05729.12 KDO23128.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KDO23128.1 - 0.016 14.9 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO23128.1 - 0.017 15.6 0.0 0.054 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO23128.1 - 0.019 15.1 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 KDO23128.1 - 0.021 13.1 6.9 0.034 12.4 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 KDO23128.1 - 0.022 15.0 0.0 0.084 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KDO23128.1 - 0.026 14.3 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KDO23128.1 - 0.036 14.5 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.6 KDO23128.1 - 0.048 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KDO23128.1 - 0.051 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 KDO23128.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 KDO23128.1 - 0.17 12.2 0.0 0.56 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO23128.1 - 0.18 11.0 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mpp10 PF04006.12 KDO23128.1 - 0.2 10.0 9.8 0.31 9.4 9.8 1.1 1 0 0 1 1 1 0 Mpp10 protein TsaE PF02367.17 KDO23128.1 - 0.2 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KDO23128.1 - 0.2 11.0 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KDO23128.1 - 0.21 11.3 0.0 0.49 10.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Osteopontin PF00865.18 KDO23128.1 - 0.86 9.0 25.8 1.7 8.1 25.8 1.4 1 0 0 1 1 1 0 Osteopontin SDA1 PF05285.12 KDO23128.1 - 1.5 8.2 16.9 2.7 7.3 16.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KDO23128.1 - 1.6 6.9 18.1 2.4 6.3 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KDO23128.1 - 1.9 7.8 12.3 3.6 6.9 12.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 KDO23128.1 - 2.4 7.2 12.0 4.3 6.4 12.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 KDO23128.1 - 3.1 5.8 31.6 5.2 5.0 31.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 KDO23128.1 - 6.4 6.3 9.8 14 5.2 9.8 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TFB6 PF17110.5 KDO23128.1 - 6.6 6.4 8.2 16 5.2 8.2 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH AAA PF00004.29 KDO23129.1 - 4.1e-06 27.3 0.0 8.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO23129.1 - 1.5e-05 25.5 0.0 7.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KDO23129.1 - 7.8e-05 22.3 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KDO23129.1 - 0.00011 22.1 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_5 PF07728.14 KDO23129.1 - 0.00023 21.1 0.0 0.0019 18.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KDO23129.1 - 0.00094 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 KDO23129.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 KDO23129.1 - 0.0087 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO23129.1 - 0.0093 16.2 0.1 0.031 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO23129.1 - 0.0096 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO23129.1 - 0.012 15.3 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KDO23129.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KDO23129.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO23129.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase TniB PF05621.11 KDO23129.1 - 0.032 13.6 0.1 2.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein NB-ARC PF00931.22 KDO23129.1 - 0.043 13.0 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KDO23129.1 - 0.049 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 KDO23129.1 - 0.053 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KDO23129.1 - 0.074 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KDO23129.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KDO23129.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 KDO23129.1 - 0.098 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KDO23129.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KDO23129.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Zeta_toxin PF06414.12 KDO23129.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 KDO23129.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO23129.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KDO23129.1 - 0.21 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit OAR PF03826.17 KDO23132.1 - 0.14 12.1 0.8 1 9.3 0.1 2.3 2 0 0 2 2 2 0 OAR domain PDCD7 PF16021.5 KDO23133.1 - 0.038 13.1 0.9 0.053 12.6 0.9 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 RE_HindVP PF09519.10 KDO23133.1 - 0.063 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease HA2 PF04408.23 KDO23136.1 - 1.9e-20 73.2 0.1 3.5e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KDO23136.1 - 7.1e-13 48.9 0.0 1.5e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO23136.1 - 2.4e-09 37.2 0.1 4.8e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KDO23136.1 - 3.6e-05 24.1 0.1 6.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO23136.1 - 7.6e-05 23.0 0.1 0.00028 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO23136.1 - 8.5e-05 22.4 0.2 0.00013 21.7 0.2 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KDO23136.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KDO23136.1 - 0.0024 17.9 0.1 0.0046 16.9 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 KDO23136.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KDO23136.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 KDO23136.1 - 0.031 13.9 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 KDO23136.1 - 0.031 13.7 0.1 0.074 12.5 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KDO23136.1 - 0.037 14.5 0.1 0.61 10.6 0.1 2.2 1 1 1 2 2 2 0 ABC transporter AAA_16 PF13191.6 KDO23136.1 - 0.04 14.3 0.2 0.1 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain UvrD-helicase PF00580.21 KDO23136.1 - 0.046 13.2 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KDO23136.1 - 0.049 13.0 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KDO23136.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DENN PF02141.21 KDO23138.1 - 3.1e-53 180.5 4.4 6e-53 179.6 4.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain ArfGap PF01412.18 KDO23138.1 - 2.6e-29 101.7 0.0 5.2e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf uDENN PF03456.18 KDO23138.1 - 3.5e-14 53.3 0.2 7.7e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KDO23138.1 - 2.9e-11 43.2 1.5 9e-11 41.6 1.5 1.9 1 0 0 1 1 1 1 dDENN domain DUF3490 PF11995.8 KDO23138.1 - 0.07 13.0 0.0 0.07 13.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3490) IQ PF00612.27 KDO23138.1 - 1.3 9.0 32.4 0.22 11.4 3.5 6.3 5 1 0 5 5 5 0 IQ calmodulin-binding motif WD40 PF00400.32 KDO23139.1 - 1.1e-10 41.9 15.3 0.0016 19.2 0.9 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23139.1 - 2.4e-08 34.2 1.1 0.024 14.9 0.0 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO23139.1 - 9.1e-05 22.4 4.8 0.0015 18.4 0.8 3.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KDO23139.1 - 0.012 14.4 0.3 1.5 7.4 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like PD40 PF07676.12 KDO23139.1 - 0.16 11.9 0.1 2.1 8.4 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pectate_lyase22 PF14583.6 KDO23140.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Oligogalacturonate lyase DFRP_C PF16543.5 KDO23140.1 - 0.2 12.2 0.2 0.31 11.6 0.2 1.2 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 FA_hydroxylase PF04116.13 KDO23141.1 - 1.8e-22 80.1 10.6 1.8e-22 80.1 10.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UQ_con PF00179.26 KDO23143.1 - 2.9e-41 140.4 0.0 3.9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KDO23143.1 - 0.004 17.4 1.2 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 RWD domain Cwf_Cwc_15 PF04889.12 KDO23143.1 - 0.013 15.2 5.8 0.018 14.8 5.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 KDO23143.1 - 0.026 12.6 0.4 0.03 12.4 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 KDO23143.1 - 0.031 14.3 1.5 0.04 13.9 1.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TLP-20 PF06088.11 KDO23143.1 - 0.051 13.5 1.4 0.066 13.1 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Myc_N PF01056.18 KDO23143.1 - 0.063 13.2 5.5 0.084 12.8 5.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 KDO23143.1 - 0.093 12.0 3.5 0.12 11.7 3.5 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KDO23143.1 - 0.42 10.3 2.6 0.65 9.6 2.6 1.2 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 KDO23143.1 - 0.51 10.8 13.0 0.9 10.0 13.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ThiF PF00899.21 KDO23144.1 - 1.6e-37 129.2 0.1 2.5e-37 128.6 0.1 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KDO23144.1 - 0.0018 18.5 2.0 0.008 16.4 2.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KDO23144.1 - 0.0071 16.6 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KDO23144.1 - 0.014 14.9 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KDO23144.1 - 0.027 14.1 0.2 0.1 12.2 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KDO23144.1 - 0.038 13.2 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain RcpB PF16971.5 KDO23144.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit PseudoU_synth_1 PF01416.20 KDO23145.1 - 9.8e-21 74.3 0.0 1.3e-15 57.8 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase LRR_6 PF13516.6 KDO23146.1 - 1.7e-18 65.0 38.6 0.001 18.9 0.0 13.4 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 KDO23146.1 - 7.5e-17 61.2 17.1 0.0061 17.0 0.1 9.0 6 2 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO23146.1 - 2.1e-14 53.0 30.3 0.0001 22.0 0.7 7.8 4 2 6 10 10 10 7 Leucine rich repeat LRR_1 PF00560.33 KDO23146.1 - 0.0011 19.2 23.6 6 7.8 0.1 11.4 13 1 0 13 13 13 1 Leucine Rich Repeat LRR_9 PF14580.6 KDO23146.1 - 0.0037 16.8 0.2 0.18 11.3 0.0 3.3 1 1 2 4 4 4 1 Leucine-rich repeat FAD_binding_6 PF00970.24 KDO23147.1 - 2.4e-34 117.6 0.0 5.7e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KDO23147.1 - 1.4e-30 106.1 0.0 2.6e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KDO23147.1 - 0.00017 21.8 0.0 0.01 16.0 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KDO23147.1 - 0.00068 19.8 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Glycos_transf_1 PF00534.20 KDO23148.1 - 1.5e-20 73.4 0.0 3.6e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO23148.1 - 3.8e-19 69.5 0.2 7.3e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO23148.1 - 1.2e-09 38.4 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KDO23149.1 - 1.4e-19 70.2 0.0 3.1e-19 69.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO23149.1 - 4.3e-18 66.0 0.1 7.1e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO23149.1 - 1.5e-09 38.1 0.1 2.9e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tup_N PF08581.10 KDO23150.1 - 0.00052 20.3 1.3 0.00052 20.3 1.3 6.0 3 2 1 5 5 5 1 Tup N-terminal SlyX PF04102.12 KDO23150.1 - 0.31 11.7 21.1 1.4 9.6 0.2 6.0 3 1 2 5 5 5 0 SlyX CCDC92 PF14916.6 KDO23150.1 - 2.4 8.0 13.2 4.5 7.1 0.9 3.6 3 1 0 3 3 3 0 Coiled-coil domain of unknown function Abhydrolase_6 PF12697.7 KDO23151.1 - 9.8e-13 49.2 1.9 1.3e-12 48.8 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO23151.1 - 1.8e-12 47.5 0.0 2.6e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO23151.1 - 7.2e-09 35.3 0.1 0.0005 19.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Hydrolase_4 PF12146.8 KDO23152.1 - 0.0002 20.7 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO23152.1 - 0.0063 17.1 0.1 0.0067 17.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO23152.1 - 0.026 14.2 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold HopA1 PF17914.1 KDO23152.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 HopA1 effector protein family Abhydrolase_1 PF00561.20 KDO23153.1 - 1.7e-07 31.2 0.1 2.1e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO23153.1 - 6.5e-05 23.6 4.4 7.9e-05 23.4 4.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO23154.1 - 1.2e-07 31.3 0.5 2.5e-07 30.2 0.5 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KDO23154.1 - 4.5e-05 23.4 0.1 6.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KDO23154.1 - 0.00015 21.5 0.0 0.016 14.9 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO23154.1 - 0.006 16.1 0.1 2.1 7.8 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KDO23154.1 - 0.011 15.3 0.2 0.029 14.0 0.2 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KDO23155.1 - 2.8e-12 47.7 6.8 3.8e-12 47.3 6.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO23155.1 - 1.5e-10 41.2 0.4 6.4e-08 32.5 0.3 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO23155.1 - 2.4e-09 36.8 0.7 1.6e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO23155.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KDO23155.1 - 0.18 11.5 0.1 9.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KDO23155.1 - 0.22 11.0 0.3 1 8.8 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glycos_transf_1 PF00534.20 KDO23156.1 - 9.7e-14 51.3 0.0 1.6e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO23156.1 - 5.5e-13 49.5 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO23156.1 - 2.6e-06 27.7 0.0 8.6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KDO23156.1 - 0.031 14.3 0.1 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 NDUF_C2 PF06374.11 KDO23156.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) CH PF00307.31 KDO23157.1 - 4.5e-06 26.8 0.0 6.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Aminotran_5 PF00266.19 KDO23158.1 - 8.9e-87 291.4 0.0 1.1e-86 291.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KDO23158.1 - 0.00018 20.9 0.1 0.00024 20.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KDO23158.1 - 0.0011 18.4 0.4 0.0018 17.7 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Holin_9 PF16936.5 KDO23158.1 - 0.087 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative holin AroM PF07302.11 KDO23158.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 AroM protein Sigma70_r1_1 PF03979.14 KDO23160.1 - 0.15 12.2 0.0 4.3 7.5 0.0 2.3 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 zf-CCCH PF00642.24 KDO23162.1 - 1.8e-10 40.5 9.9 1.9e-07 30.8 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO23162.1 - 5.5e-06 27.0 6.4 0.012 16.3 2.2 2.7 2 1 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KDO23162.1 - 3.9e-05 23.5 13.1 0.0016 18.4 2.6 2.7 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KDO23162.1 - 0.0014 18.3 14.3 0.0029 17.4 2.9 2.8 2 1 0 2 2 2 2 CCCH-type zinc finger RRM_1 PF00076.22 KDO23162.1 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 KDO23162.1 - 0.047 14.2 7.5 0.42 11.2 1.6 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4778 PF16008.5 KDO23162.1 - 0.68 9.9 12.2 1.1 9.3 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF4375 PF14300.6 KDO23162.1 - 4.8 7.5 7.1 1.3 9.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) V_ATPase_I PF01496.19 KDO23162.1 - 5 4.9 8.2 5.8 4.7 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DEAD PF00270.29 KDO23163.1 - 1.9e-26 92.9 0.0 3.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KDO23163.1 - 9.3e-19 68.0 0.3 2.3e-18 66.7 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KDO23163.1 - 1.2e-12 48.1 0.0 3.3e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO23163.1 - 4.3e-05 23.6 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Spt5_N PF11942.8 KDO23164.1 - 8.2e-05 23.5 0.3 0.00012 22.9 0.3 1.2 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal PPV_E1_N PF00524.18 KDO23164.1 - 0.0032 17.9 2.2 0.0048 17.3 2.2 1.3 1 0 0 1 1 1 1 E1 Protein, N terminal domain WH2 PF02205.20 KDO23164.1 - 0.18 11.7 0.1 27 4.8 0.0 2.3 2 0 0 2 2 2 0 WH2 motif DNA_pol_phi PF04931.13 KDO23164.1 - 0.81 7.7 3.3 0.93 7.5 3.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi WASH_WAHD PF11945.8 KDO23165.1 - 3.5e-40 138.4 0.0 5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 KDO23165.1 - 0.0068 16.2 0.5 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 WH2 motif DUF885 PF05960.11 KDO23165.1 - 0.28 10.8 1.3 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Guanylate_cyc PF00211.20 KDO23166.1 - 3.3e-90 300.6 0.1 1.4e-50 171.4 0.0 2.9 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 KDO23166.1 - 1.3e-50 172.5 14.2 1.3e-50 172.5 14.2 2.5 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO23166.1 - 9.5e-23 79.7 0.8 3.5e-22 77.9 0.8 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO23166.1 - 2e-08 34.8 3.2 4.3e-05 23.9 1.7 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO23166.1 - 4.2e-08 33.2 0.0 3.3e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO23166.1 - 5.3e-08 32.6 0.0 5.3e-08 32.6 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO23166.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TPR_12 PF13424.6 KDO23167.1 - 1.7e-12 47.4 3.8 5.8e-05 23.3 0.1 6.6 7 1 2 9 9 8 4 Tetratricopeptide repeat EF-hand_5 PF13202.6 KDO23167.1 - 3.9e-10 38.8 0.0 2.6e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO23167.1 - 4.8e-10 39.7 0.0 1.1e-07 32.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO23167.1 - 5.4e-09 35.3 0.1 0.00085 19.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KDO23167.1 - 3.7e-08 32.4 0.0 0.0021 17.5 0.0 2.7 2 0 0 2 2 2 2 EF hand TPR_10 PF13374.6 KDO23167.1 - 9.4e-08 31.7 3.5 0.1 12.5 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat EF-hand_8 PF13833.6 KDO23167.1 - 1.1e-07 31.6 0.0 0.026 14.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair TPR_1 PF00515.28 KDO23167.1 - 0.00087 19.0 2.0 0.78 9.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23167.1 - 0.0015 18.5 6.5 0.58 10.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO23167.1 - 0.66 10.8 8.8 6.6 7.7 1.4 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO23167.1 - 4.3 8.2 12.4 69 4.4 0.0 5.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF659 PF04937.15 KDO23168.1 - 4.4e-20 72.1 0.1 7.9e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KDO23168.1 - 1.2e-06 28.2 0.0 6.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KDO23168.1 - 2e-06 27.7 5.5 2e-06 27.7 5.5 2.4 2 0 0 2 2 2 1 BED zinc finger UPF0175 PF03683.13 KDO23168.1 - 0.19 11.5 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Myb_DNA-binding PF00249.31 KDO23169.1 - 9.2e-20 70.6 1.7 2.1e-12 47.0 0.9 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO23169.1 - 2.5e-09 37.2 1.1 0.00034 20.8 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO23169.1 - 1.5e-07 31.2 1.4 0.018 14.9 0.3 2.6 2 0 0 2 2 2 2 Myb DNA-binding like DUF1086 PF06461.11 KDO23169.1 - 0.003 17.4 0.4 3.1 7.7 0.0 2.4 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1086) SANT_DAMP1_like PF16282.5 KDO23169.1 - 0.095 12.9 2.4 1.2 9.4 0.1 2.5 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF2807 PF10988.8 KDO23170.1 - 6.1e-14 52.2 15.3 1.1e-07 31.8 6.7 2.5 2 1 1 3 3 3 2 Putative auto-transporter adhesin, head GIN domain DnaJ PF00226.31 KDO23171.1 - 0.015 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Fis1_TPR_C PF14853.6 KDO23172.1 - 1e-13 51.1 1.3 1.2e-13 50.9 0.2 1.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KDO23172.1 - 1.6e-06 27.8 1.8 7.2e-06 25.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23172.1 - 0.0018 18.9 0.3 0.024 15.4 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO23172.1 - 0.0026 17.5 1.4 0.0073 16.1 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO23172.1 - 0.017 15.3 3.5 0.031 14.5 2.1 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KDO23172.1 - 0.032 14.9 1.2 0.74 10.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4071 PF13281.6 KDO23172.1 - 0.048 12.7 0.2 0.053 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Fis1_TPR_N PF14852.6 KDO23172.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat ANAPC8 PF04049.13 KDO23172.1 - 0.12 12.4 1.9 0.43 10.6 0.6 2.0 1 1 1 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Cornichon PF03311.14 KDO23173.1 - 2.5e-30 105.3 1.0 3e-30 105.0 1.0 1.1 1 0 0 1 1 1 1 Cornichon protein DCP2 PF05026.13 KDO23174.1 - 9.3e-17 61.1 2.5 1.3e-16 60.6 2.5 1.2 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KDO23174.1 - 2.8e-10 40.4 0.1 5.3e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain NUDIX_2 PF13869.6 KDO23174.1 - 0.053 13.1 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase Methyltransf_2 PF00891.18 KDO23177.1 - 0.17 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Rieske PF00355.26 KDO23180.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DEAD PF00270.29 KDO23184.1 - 4e-44 150.5 0.1 6.9e-44 149.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO23184.1 - 5.2e-32 110.5 0.1 2.1e-30 105.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO23184.1 - 9.3e-06 25.7 0.0 4.1e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KDO23184.1 - 0.0013 19.1 0.1 0.0035 17.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO23184.1 - 0.0077 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO23184.1 - 0.017 15.4 0.3 0.074 13.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KDO23184.1 - 0.052 13.0 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 KDO23184.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KDO23184.1 - 0.08 12.9 0.2 0.62 10.0 0.0 2.5 1 1 1 2 2 2 0 Flavivirus DEAD domain PrmA PF06325.13 KDO23186.1 - 3.8e-06 26.5 0.0 5.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KDO23186.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_3 PF01596.17 KDO23187.1 - 1.4e-35 122.4 0.0 2.6e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase UPF0176_N PF17773.1 KDO23187.1 - 8.3e-20 71.0 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 KDO23187.1 - 1.8e-18 66.7 7.8 3.6e-18 65.7 7.8 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Methyltransf_24 PF13578.6 KDO23187.1 - 1.7e-13 51.5 0.1 5.7e-13 49.8 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO23187.1 - 2.4e-08 33.9 0.0 5.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO23187.1 - 1.5e-07 32.0 0.0 3.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 KDO23187.1 - 1.6e-07 31.8 0.0 4.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain MTS PF05175.14 KDO23187.1 - 5e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KDO23187.1 - 4.3e-06 27.3 0.0 8.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO23187.1 - 0.00013 22.6 0.0 0.00032 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KDO23187.1 - 0.00095 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KDO23187.1 - 0.0012 18.5 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) Spermine_synth PF01564.17 KDO23187.1 - 0.0021 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF938 PF06080.12 KDO23187.1 - 0.0091 15.8 0.2 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KDO23187.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KDO23187.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KDO23187.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KDO23187.1 - 0.045 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain La PF05383.17 KDO23189.1 - 2.2e-17 62.8 0.2 4.2e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KDO23189.1 - 0.0018 18.0 0.0 0.0046 16.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3228 PF11539.8 KDO23190.1 - 1.3e-76 256.4 0.0 1.6e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) tRNA_bind PF01588.20 KDO23191.1 - 6.5e-25 87.1 0.0 1.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain RNA_pol_Rpc4 PF05132.14 KDO23191.1 - 0.53 10.7 5.1 0.85 10.0 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med3 PF11593.8 KDO23191.1 - 6 5.9 15.6 8.9 5.4 15.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YIF1 PF03878.15 KDO23192.1 - 1.2e-57 195.3 2.4 1.5e-57 194.9 2.4 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KDO23192.1 - 2e-07 30.9 2.0 5.4e-07 29.5 2.0 1.7 1 1 0 1 1 1 1 Yip1 domain DUF468 PF04318.12 KDO23192.1 - 0.1 13.4 0.4 22 5.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF468) DAGAT PF03982.13 KDO23193.1 - 1.5e-49 168.6 0.0 1.8e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Cullin PF00888.22 KDO23194.1 - 1.7e-126 423.3 0.0 2.2e-126 423.0 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KDO23194.1 - 4.9e-15 55.3 0.1 2.4e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain PseudoU_synth_1 PF01416.20 KDO23195.1 - 3e-40 137.0 0.3 2.6e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase DIE2_ALG10 PF04922.12 KDO23196.1 - 3.3e-113 379.0 24.7 4e-113 378.7 24.7 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family PAP_assoc PF03828.19 KDO23197.1 - 1.3e-15 57.3 0.3 7.4e-15 54.9 0.0 2.4 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KDO23197.1 - 6.1e-07 29.6 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KDO23197.1 - 0.0098 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Mei5 PF10376.9 KDO23198.1 - 0.0097 15.8 1.1 0.011 15.6 1.1 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Miga PF10265.9 KDO23198.1 - 0.054 12.5 4.4 0.063 12.3 4.4 1.0 1 0 0 1 1 1 0 Mitoguardin DUF4602 PF15375.6 KDO23199.1 - 1.6e-23 83.5 8.0 1.8e-23 83.4 8.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) DUF4661 PF15576.6 KDO23199.1 - 0.25 11.2 1.9 0.29 11.0 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) ASH PF15780.5 KDO23200.1 - 2.2e-64 213.8 27.3 0.00024 21.3 0.0 25.8 25 2 1 27 27 27 16 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KDO23200.1 - 4.8e-21 74.8 2.4 0.067 13.4 0.0 11.6 13 0 0 13 13 13 6 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KDO23200.1 - 4.9e-18 65.0 1.8 0.99 9.3 0.0 14.0 15 1 0 15 15 15 6 MSP (Major sperm protein) domain DUF1573 PF07610.11 KDO23200.1 - 1.2e-16 60.5 0.0 0.18 11.8 0.0 14.1 15 0 0 15 15 15 2 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 KDO23200.1 - 1.2e-12 47.6 0.2 0.28 10.1 0.0 10.3 13 1 0 13 13 13 4 MYCBP-associated protein family TMEM131_like PF12371.8 KDO23200.1 - 4.5e-09 36.4 12.6 1.8 8.9 0.0 11.1 14 0 0 14 14 14 3 Transmembrane protein 131-like MFS_1 PF07690.16 KDO23201.1 - 1.5e-36 126.1 34.6 3.7e-35 121.5 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.31 KDO23202.1 - 2.7e-15 56.7 0.0 5.5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO23202.1 - 6.2e-14 52.2 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KDO23202.1 - 4.8e-07 30.4 0.6 9.8e-07 29.4 0.6 1.5 1 0 0 1 1 1 1 RecQ zinc-binding AAA_22 PF13401.6 KDO23202.1 - 0.038 14.3 0.0 0.71 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Stn1 PF10451.9 KDO23203.1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KDO23203.1 - 3.2e-05 23.8 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KDO23203.1 - 0.002 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 LBR_tudor PF09465.10 KDO23204.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Abhydrolase_6 PF12697.7 KDO23205.1 - 5.1e-30 105.7 1.5 6.6e-30 105.4 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO23205.1 - 1e-12 47.8 0.3 2.6e-12 46.5 0.3 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO23205.1 - 3e-12 46.7 0.1 9e-12 45.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KDO23205.1 - 0.0002 20.5 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 KDO23205.1 - 0.00076 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KDO23205.1 - 0.001 18.9 0.1 0.0021 18.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KDO23205.1 - 0.0011 18.8 0.3 0.055 13.3 0.3 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KDO23205.1 - 0.0019 17.2 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 KDO23205.1 - 0.0021 18.2 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KDO23205.1 - 0.01 15.5 0.1 0.026 14.2 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KDO23205.1 - 0.028 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KDO23205.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CAP_GLY PF01302.25 KDO23206.1 - 2.5e-17 62.7 0.1 4.4e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Cytochrom_B_C PF00032.17 KDO23207.1 - 2.6 8.4 8.3 0.31 11.3 0.7 2.8 1 1 2 3 3 3 0 Cytochrome b(C-terminal)/b6/petD TPH PF13868.6 KDO23210.1 - 1.7e-06 26.8 19.3 2e-06 26.6 19.3 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain FAM184 PF15665.5 KDO23210.1 - 0.036 13.8 13.7 0.039 13.7 13.7 1.0 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SpoU_sub_bind PF08032.12 KDO23210.1 - 1.2 9.4 4.9 4 7.8 0.8 2.6 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Vma12 PF11712.8 KDO23210.1 - 6.7 6.8 6.7 17 5.4 5.7 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Arm-DNA-bind_5 PF17293.2 KDO23210.1 - 7.4 7.1 9.8 28 5.2 8.9 2.3 1 1 1 2 2 2 0 Arm DNA-binding domain Ank_2 PF12796.7 KDO23211.1 - 7.6e-26 90.5 28.1 1.2e-08 35.4 1.1 7.0 3 1 7 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23211.1 - 7.2e-13 48.8 19.5 8.1e-05 23.1 0.0 7.8 7 2 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23211.1 - 1.3e-11 44.5 18.4 0.13 12.6 0.0 9.0 6 2 4 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23211.1 - 7.1e-08 32.1 29.2 1.8 9.4 0.0 11.4 11 2 2 13 13 13 4 Ankyrin repeat DUF249 PF03158.13 KDO23211.1 - 0.02 14.6 0.0 0.47 10.1 0.0 3.1 2 1 0 2 2 2 0 Multigene family 530 protein Ank PF00023.30 KDO23211.1 - 0.027 14.9 19.6 0.96 10.0 0.0 7.7 8 2 0 8 8 8 0 Ankyrin repeat DUF5059 PF16502.5 KDO23212.1 - 0.001 17.9 0.8 0.0015 17.4 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5059) DHC_N2 PF08393.13 KDO23212.1 - 0.004 16.3 0.6 0.036 13.2 0.2 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DUF1957 PF09210.11 KDO23212.1 - 0.63 10.5 4.5 20 5.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1957) APG6 PF04111.12 KDO23213.1 - 6.1e-42 143.6 0.0 1e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KDO23213.1 - 2.8e-06 27.9 1.0 4.6e-06 27.2 1.0 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Gag_p17 PF00540.18 KDO23213.1 - 0.09 12.8 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) Ank_2 PF12796.7 KDO23214.1 - 2e-16 60.3 8.5 4.6e-07 30.3 0.3 4.7 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23214.1 - 5.6e-10 39.6 16.8 0.013 16.1 0.2 6.0 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23214.1 - 4.7e-08 33.1 12.3 0.033 14.5 0.1 6.9 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23214.1 - 0.0001 22.4 12.4 3 8.7 0.0 8.0 9 1 1 10 10 10 2 Ankyrin repeat Ank_2 PF12796.7 KDO23215.1 - 8.5e-25 87.2 11.4 7.3e-07 29.7 0.2 6.5 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23215.1 - 5.3e-14 52.4 25.1 0.17 12.5 0.2 9.2 6 3 6 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23215.1 - 1.2e-08 34.5 24.6 1 10.1 0.0 11.9 14 0 0 14 14 14 1 Ankyrin repeat Ank_5 PF13857.6 KDO23215.1 - 2.1e-08 34.2 19.0 0.54 10.7 0.0 9.8 4 3 6 10 10 10 1 Ankyrin repeats (many copies) DUF249 PF03158.13 KDO23215.1 - 0.0034 17.1 0.0 0.78 9.4 0.0 3.1 3 1 0 3 3 3 1 Multigene family 530 protein Ank PF00023.30 KDO23215.1 - 0.25 11.9 19.1 51 4.6 0.3 7.9 6 3 0 6 6 6 0 Ankyrin repeat RCR PF12273.8 KDO23217.1 - 0.1 13.3 0.3 0.48 11.1 0.0 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FUN14 PF04930.15 KDO23218.1 - 7e-23 80.9 0.4 1e-22 80.3 0.4 1.2 1 0 0 1 1 1 1 FUN14 family Dockerin_1 PF00404.18 KDO23218.1 - 0.016 15.4 0.5 0.029 14.5 0.5 1.5 1 0 0 1 1 1 0 Dockerin type I domain SoDot-IcmSS PF16848.5 KDO23218.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative EF-hand_6 PF13405.6 KDO23218.1 - 0.092 12.7 0.3 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain Cas_CT1975 PF09344.10 KDO23218.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 CT1975-like protein YqzM PF14141.6 KDO23218.1 - 0.16 12.1 1.0 0.77 9.9 0.0 2.3 3 0 0 3 3 3 0 YqzM-like protein WW PF00397.26 KDO23219.1 - 3.3e-07 30.3 1.3 5.1e-07 29.7 1.3 1.3 1 0 0 1 1 1 1 WW domain Cytochrom_c3_2 PF14537.6 KDO23219.1 - 0.016 15.6 0.8 0.031 14.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.6 KDO23219.1 - 0.064 13.3 1.0 0.61 10.1 1.1 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-RING_7 PF02591.15 KDO23219.1 - 0.093 12.9 0.3 3.8 7.8 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain LCE6A PF15858.5 KDO23219.1 - 7 7.5 16.4 3.5 8.5 0.7 2.8 3 0 0 3 3 3 0 Late cornified envelope protein 6A family CAP_N PF01213.19 KDO23219.1 - 8.2 5.8 11.6 0.27 10.7 5.7 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sin_N PF04801.13 KDO23220.1 - 3.3e-66 224.3 0.1 6e-66 223.4 0.1 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region WD40_4 PF16300.5 KDO23221.1 - 6.7e-30 102.7 3.3 5.3e-16 58.2 0.1 3.8 3 0 0 3 3 3 2 Type of WD40 repeat WD40 PF00400.32 KDO23221.1 - 2.1e-24 85.3 12.9 6e-07 30.1 0.1 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23221.1 - 3.1e-10 40.2 0.1 0.35 11.2 0.0 5.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 KDO23221.1 - 3.8e-08 33.1 0.0 5.2e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) DUF5628 PF18621.1 KDO23221.1 - 0.029 14.8 0.1 0.63 10.5 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5628) Nup160 PF11715.8 KDO23221.1 - 0.18 10.4 4.8 0.56 8.8 0.1 2.9 3 1 0 3 3 3 0 Nucleoporin Nup120/160 PRCC PF10253.9 KDO23221.1 - 6.4 7.5 6.5 2.9 8.6 3.8 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Mg_trans_NIPA PF05653.14 KDO23222.1 - 1.1e-26 93.6 9.3 1.2e-14 54.1 0.8 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KDO23222.1 - 0.00027 21.1 18.1 0.00052 20.2 3.5 3.5 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.6 KDO23222.1 - 0.066 12.8 6.3 0.095 12.3 0.2 2.5 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter BatA PF07584.11 KDO23222.1 - 0.29 11.5 8.0 1.7 9.1 0.1 3.2 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal Multi_Drug_Res PF00893.19 KDO23222.1 - 0.41 11.3 10.1 2.8 8.7 2.0 2.9 2 0 0 2 2 2 0 Small Multidrug Resistance protein TMEM234 PF10639.9 KDO23222.1 - 0.67 10.0 3.8 1.9 8.6 0.5 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF4131 PF13567.6 KDO23222.1 - 2 8.0 10.5 8.7 6.0 1.7 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) AWPM-19 PF05512.11 KDO23222.1 - 4.6 7.4 6.7 0.52 10.5 1.0 2.3 2 1 0 2 2 2 0 AWPM-19-like family Spc7 PF08317.11 KDO23223.1 - 0.0069 15.3 1.4 0.017 14.0 1.4 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Knl1_RWD_C PF18210.1 KDO23223.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain DUF1664 PF07889.12 KDO23223.1 - 0.13 12.3 0.3 17 5.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 KDO23223.1 - 0.18 11.1 1.5 3.4 6.9 0.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-B_dimeris PF09026.10 KDO23223.1 - 2.9 8.3 23.0 7.5 7.0 9.2 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain p25-alpha PF05517.12 KDO23225.1 - 0.0052 16.9 0.0 0.38 10.9 0.0 3.2 3 0 0 3 3 3 1 p25-alpha EF-hand_like PF09279.11 KDO23225.1 - 0.082 13.4 2.2 3.3 8.3 0.1 3.2 3 1 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like ABC_tran_CTD PF16326.5 KDO23225.1 - 6.1 7.2 6.9 19 5.6 1.3 4.2 5 0 0 5 5 5 0 ABC transporter C-terminal domain PAN_4 PF14295.6 KDO23226.1 - 6.3e-23 80.4 35.4 4.5e-07 29.7 4.5 4.6 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 KDO23226.1 - 3.2e-07 30.4 35.6 0.0071 16.4 2.0 4.3 4 0 0 4 4 4 4 PAN-like domain Whib PF02467.16 KDO23226.1 - 0.2 12.3 13.0 6.7 7.4 0.2 4.1 4 0 0 4 4 4 0 Transcription factor WhiB PAN_3 PF08277.12 KDO23226.1 - 2.6 7.9 32.7 0.15 11.9 3.5 4.3 4 0 0 4 4 4 0 PAN-like domain PAN_4 PF14295.6 KDO23227.1 - 1.1e-12 47.7 12.5 4.3e-06 26.5 3.0 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 KDO23227.1 - 0.38 10.9 10.3 0.83 9.8 2.1 2.3 2 0 0 2 2 2 0 PAN-like domain PAN_4 PF14295.6 KDO23228.1 - 4.5e-22 77.7 40.2 5.4e-07 29.4 5.0 4.7 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 KDO23228.1 - 7.7e-05 22.7 39.9 0.026 14.6 2.5 4.3 4 0 0 4 4 4 4 PAN-like domain DUF1397 PF07165.11 KDO23228.1 - 0.017 14.6 16.9 0.074 12.5 0.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1397) Whib PF02467.16 KDO23228.1 - 0.15 12.7 18.7 3.1 8.5 0.2 4.2 4 0 0 4 4 4 0 Transcription factor WhiB PAN_4 PF14295.6 KDO23229.1 - 3.2e-24 84.6 28.7 1.2e-07 31.5 2.8 4.5 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 KDO23229.1 - 0.022 14.9 30.2 0.13 12.4 3.5 3.9 4 0 0 4 4 4 0 PAN-like domain DUF4211 PF13926.6 KDO23229.1 - 0.031 14.3 12.9 2.2 8.3 0.4 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4211) Beta-lactamase PF00144.24 KDO23230.1 - 1.3e-38 133.1 0.5 2e-38 132.5 0.5 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO23230.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KDO23231.1 - 9.5e-43 146.7 1.5 1.4e-42 146.1 1.5 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO23231.1 - 0.054 13.1 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family PAN_4 PF14295.6 KDO23233.1 - 7e-20 70.7 27.9 4.9e-07 29.6 4.5 3.7 3 1 0 3 3 3 3 PAN domain PAN_2 PF08276.11 KDO23233.1 - 0.00058 19.9 26.1 0.071 13.2 3.4 3.3 3 0 0 3 3 3 3 PAN-like domain Whib PF02467.16 KDO23233.1 - 0.18 12.4 12.0 2.2 9.0 0.2 3.3 3 0 0 3 3 3 0 Transcription factor WhiB Beta-lactamase PF00144.24 KDO23234.1 - 8.9e-42 143.5 0.7 1.4e-41 142.8 0.7 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO23234.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family M16C_assoc PF08367.11 KDO23235.1 - 4e-39 134.3 0.1 7.1e-39 133.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KDO23235.1 - 3.3e-20 72.9 0.1 3.7e-14 53.2 0.0 3.9 3 1 2 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KDO23235.1 - 6.3e-10 39.2 0.0 2.6e-09 37.2 0.0 2.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3618 PF12277.8 KDO23235.1 - 0.28 11.4 4.8 0.11 12.8 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) ISN1 PF06437.11 KDO23236.1 - 7.7e-95 318.2 0.0 9.5e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Peptidase_S74 PF13884.6 KDO23237.1 - 2e-16 60.0 0.0 3.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase EGF_2 PF07974.13 KDO23237.1 - 8.2e-08 32.5 24.0 3.3e-05 24.1 6.5 2.4 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 KDO23237.1 - 0.0021 18.3 20.0 0.18 12.1 6.8 2.8 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 KDO23237.1 - 0.34 11.1 21.8 0.14 12.3 6.3 2.6 2 0 0 2 2 2 0 Laminin EGF domain hEGF PF12661.7 KDO23237.1 - 0.72 10.6 14.7 0.34 11.6 3.8 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Mod_r PF07200.13 KDO23239.1 - 0.26 11.4 4.1 0.19 11.8 1.4 2.1 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ank_5 PF13857.6 KDO23240.1 - 2e-29 101.2 32.1 0.021 15.1 0.0 12.6 2 2 11 13 13 13 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23240.1 - 2.1e-29 101.9 22.1 4e-06 27.3 0.0 6.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23240.1 - 4.2e-25 87.8 23.9 0.00047 20.7 0.4 9.1 3 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23240.1 - 2.1e-14 52.2 11.3 6.5 7.7 0.1 11.2 11 1 1 12 12 12 3 Ankyrin repeat DUF5049 PF16468.5 KDO23240.1 - 1.7e-06 27.8 0.0 3 7.8 0.0 6.4 6 1 1 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 KDO23240.1 - 0.0011 19.4 13.1 1.7e+02 2.9 0.0 9.1 3 2 1 4 4 4 0 Ankyrin repeat DUF3322 PF11795.8 KDO23240.1 - 0.054 13.5 0.6 11 6.0 0.0 3.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DLH PF01738.18 KDO23242.1 - 1.5e-11 44.3 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KDO23242.1 - 0.029 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Myosin_head PF00063.21 KDO23243.1 - 3.8e-177 590.5 0.0 3.8e-174 580.6 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 KDO23243.1 - 2.1e-14 51.9 26.4 9.2e-05 21.9 0.3 5.8 5 0 0 5 5 5 4 IQ calmodulin-binding motif WW PF00397.26 KDO23243.1 - 1.4e-07 31.5 0.0 3.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 WW domain TMF_DNA_bd PF12329.8 KDO23243.1 - 0.14 12.2 5.0 0.076 13.0 1.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding 5_3_exonuc PF01367.20 KDO23243.1 - 1.6 9.4 3.7 0.99 10.1 0.2 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold UPF0242 PF06785.11 KDO23243.1 - 2.1 8.4 11.5 4.4 7.4 11.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 KDO23243.1 - 3.1 8.0 9.1 0.24 11.5 1.1 3.2 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF384 PF04064.13 KDO23246.1 - 0.071 13.0 0.3 0.16 11.8 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF384) PGM_PMM_III PF02880.16 KDO23246.1 - 0.087 13.0 0.1 0.098 12.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III HTH_12 PF08461.10 KDO23248.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TruB_C PF09142.11 KDO23249.1 - 0.0086 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal DUF3251 PF11622.8 KDO23249.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DIOX_N PF14226.6 KDO23250.1 - 6.3e-24 85.0 0.0 8.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO23250.1 - 1.9e-21 76.4 0.0 4.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cyclin_N PF00134.23 KDO23251.1 - 8.3e-35 119.3 0.6 1.7e-34 118.3 0.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF899 PF05988.12 KDO23252.1 - 0.06 12.9 0.9 0.088 12.3 0.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) CAP_N PF01213.19 KDO23252.1 - 0.067 12.7 8.6 0.096 12.2 8.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KDO23252.1 - 0.45 10.6 6.3 0.53 10.3 6.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CCDC53 PF10152.9 KDO23252.1 - 2.2 8.7 5.8 3 8.2 5.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SVIP PF15811.5 KDO23252.1 - 6.9 7.2 10.6 0.95 10.0 4.7 2.0 2 0 0 2 2 2 0 Small VCP/p97-interacting protein PLAC8 PF04749.17 KDO23253.1 - 5.1e-16 59.5 7.4 6.5e-16 59.2 7.4 1.1 1 0 0 1 1 1 1 PLAC8 family PhoR PF11808.8 KDO23253.1 - 0.11 12.9 3.9 0.24 11.8 3.9 1.5 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR FixQ PF05545.11 KDO23253.1 - 9.3 6.3 9.0 0.93 9.5 2.5 2.1 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ RRM_1 PF00076.22 KDO23255.1 - 6.1e-27 93.2 0.0 1.6e-12 47.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB_2 PF02214.22 KDO23256.1 - 3.8e-09 36.8 0.0 2e-08 34.4 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain LRR_8 PF13855.6 KDO23257.1 - 4.9e-10 39.0 0.0 0.00015 21.5 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO23257.1 - 0.00051 20.4 0.0 0.0078 16.6 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO23258.1 - 1.4e-07 31.1 0.0 0.00065 19.4 0.0 3.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO23258.1 - 1.4e-05 25.3 0.0 0.0015 18.9 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO23258.1 - 0.024 15.1 0.2 55 4.9 0.0 4.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO23258.1 - 0.1 12.7 1.4 37 4.7 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat PLAC8 PF04749.17 KDO23259.1 - 1.2e-16 61.5 7.0 1.6e-16 61.1 7.0 1.2 1 0 0 1 1 1 1 PLAC8 family LapA_dom PF06305.11 KDO23259.1 - 0.0058 16.4 1.9 0.0092 15.8 1.9 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain zf-C3HC4_2 PF13923.6 KDO23260.1 - 6e-08 32.4 17.1 1e-07 31.6 17.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO23260.1 - 3.5e-05 23.6 15.9 6e-05 22.8 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO23260.1 - 4.7e-05 23.6 16.3 0.0001 22.6 16.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO23260.1 - 9.5e-05 22.2 13.7 0.00015 21.5 13.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KDO23260.1 - 0.024 14.5 8.3 0.044 13.7 8.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KDO23260.1 - 0.036 14.1 14.8 0.036 14.1 14.8 1.9 2 0 0 2 2 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO23260.1 - 0.1 12.8 12.2 0.24 11.6 12.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO23260.1 - 0.12 12.4 15.9 0.26 11.3 16.0 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Siva PF05458.12 KDO23260.1 - 0.69 9.6 7.5 1.2 8.8 7.5 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-Nse PF11789.8 KDO23260.1 - 0.86 9.5 7.1 1.5 8.7 7.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KDO23260.1 - 2 8.3 13.2 6.2 6.7 13.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KDO23260.1 - 3.4 7.6 16.2 36 4.3 16.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KDO23260.1 - 3.7 7.5 13.7 12 5.8 13.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PLAC8 PF04749.17 KDO23261.1 - 1.7e-17 64.2 14.6 2.1e-17 63.9 14.6 1.1 1 0 0 1 1 1 1 PLAC8 family Herpes_LMP1 PF05297.11 KDO23261.1 - 0.46 9.6 3.4 0.58 9.3 3.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) LRR_6 PF13516.6 KDO23262.1 - 6.8e-15 53.8 20.0 0.0074 16.3 0.0 8.4 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_1 PF00036.32 KDO23262.1 - 4.8e-09 35.1 0.0 0.0022 17.4 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO23262.1 - 6.7e-07 29.7 0.0 1.9e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO23262.1 - 9.9e-07 28.2 0.1 0.034 14.1 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain LRR_4 PF12799.7 KDO23262.1 - 9.5e-05 22.7 9.6 1.7 9.2 0.2 5.2 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) DUF4476 PF14771.6 KDO23262.1 - 0.00031 21.0 0.5 2.8 8.3 0.0 3.8 4 0 0 4 4 4 2 Domain of unknown function (DUF4476) EF-hand_5 PF13202.6 KDO23262.1 - 0.0027 17.1 0.0 0.0068 15.9 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KDO23262.1 - 0.0032 17.3 0.1 0.26 11.2 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair LRR_1 PF00560.33 KDO23262.1 - 0.0035 17.7 6.4 66 4.6 0.1 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO23262.1 - 0.034 13.9 11.6 1.8 8.4 1.4 5.7 4 1 2 6 6 6 0 Leucine rich repeat ApoLp-III PF07464.11 KDO23263.1 - 0.022 14.8 0.4 0.046 13.8 0.4 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DNA_pol_phi PF04931.13 KDO23263.1 - 9.5 4.2 10.2 15 3.5 6.9 2.0 2 0 0 2 2 2 0 DNA polymerase phi Porin_3 PF01459.22 KDO23264.1 - 4.6e-45 154.2 0.0 5.4e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin PX PF00787.24 KDO23265.1 - 7.1e-06 26.0 0.0 9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO23266.1 - 0.0039 17.1 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO23267.1 - 8.4e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO23268.1 - 4.6e-14 52.4 0.0 5.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 PX domain DUF4436 PF14494.6 KDO23269.1 - 8.4e-08 31.8 1.2 9.1e-08 31.7 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4436 PF14494.6 KDO23270.1 - 0.0004 19.8 0.5 0.0004 19.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4436 PF14494.6 KDO23271.1 - 2.4e-15 56.5 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Endonuclease_NS PF01223.23 KDO23272.1 - 3.2e-20 72.9 2.8 3.7e-18 66.2 0.5 2.1 1 1 1 2 2 2 2 DNA/RNA non-specific endonuclease PAN_4 PF14295.6 KDO23272.1 - 0.0028 17.5 0.5 0.0057 16.5 0.5 1.5 1 0 0 1 1 1 1 PAN domain SOG2 PF10428.9 KDO23272.1 - 0.67 9.1 11.1 0.86 8.7 11.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Endonuclease_NS PF01223.23 KDO23273.1 - 3.9e-28 98.8 0.1 5.5e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PAN_4 PF14295.6 KDO23273.1 - 4.2e-10 39.4 5.0 1e-09 38.1 5.0 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KDO23273.1 - 4.1e-06 26.7 0.1 9.4e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 PAN domain Endonuclea_NS_2 PF13930.6 KDO23273.1 - 0.036 14.2 0.2 0.096 12.8 0.2 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease DUF4223 PF13978.6 KDO23276.1 - 0.49 10.4 2.1 0.69 9.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) CaM_bdg_C0 PF10562.9 KDO23277.1 - 0.12 12.5 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF1240 PF06836.12 KDO23279.1 - 0.065 13.8 2.6 0.42 11.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) DUF5418 PF17439.2 KDO23280.1 - 1.2 9.2 4.0 0.92 9.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5418) Scramblase PF03803.15 KDO23281.1 - 1.4e-10 40.9 0.2 0.007 15.7 0.0 3.7 3 1 1 4 4 4 3 Scramblase UNC-93 PF05978.16 KDO23282.1 - 0.00062 19.5 1.4 0.00062 19.5 1.4 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Chromo PF00385.24 KDO23284.1 - 0.0023 17.8 0.5 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2573 PF10835.8 KDO23284.1 - 0.013 15.8 0.0 0.49 10.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) Med26 PF08711.11 KDO23285.1 - 2.4e-11 43.4 0.0 5.8e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain EF-1_beta_acid PF10587.9 KDO23285.1 - 0.0026 18.1 0.5 0.0026 18.1 0.5 4.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region PA PF02225.22 KDO23286.1 - 1.4e-07 31.4 0.0 3.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF4296 PF14129.6 KDO23286.1 - 0.011 16.3 0.0 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) DUF3867 PF12983.7 KDO23286.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) DSBA PF01323.20 KDO23286.1 - 0.14 11.9 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain C2 PF00168.30 KDO23287.1 - 1.8e-33 114.9 0.0 5.9e-08 32.9 0.0 9.2 10 0 0 10 10 10 5 C2 domain EF-hand_7 PF13499.6 KDO23287.1 - 4.9e-14 52.5 1.4 1.2e-05 25.7 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO23287.1 - 3.9e-13 47.9 0.5 9.2e-05 21.7 0.1 4.3 4 0 0 4 4 4 3 EF hand SAM_1 PF00536.30 KDO23287.1 - 6.2e-13 49.0 0.1 1.2e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO23287.1 - 2.6e-11 43.4 0.1 9.6e-11 41.6 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.6 KDO23287.1 - 2.8e-11 43.1 3.1 0.011 15.6 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO23287.1 - 5.8e-10 38.2 0.0 0.00012 21.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO23287.1 - 8.7e-10 37.7 0.0 0.011 15.6 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain Glyco_transf_8C PF08437.10 KDO23287.1 - 0.2 11.7 0.1 0.46 10.6 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal CCDC-167 PF15188.6 KDO23288.1 - 0.08 13.3 2.0 0.14 12.5 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DHR10 PF18595.1 KDO23288.1 - 0.66 10.1 8.6 1 9.4 8.6 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain MORN PF02493.20 KDO23288.1 - 3.5 7.7 7.0 14 5.8 0.0 2.9 3 0 0 3 3 3 0 MORN repeat tRNA-synt_2d PF01409.20 KDO23289.1 - 3.2e-85 285.5 0.0 4.8e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KDO23289.1 - 2.9e-20 72.3 0.1 6.2e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 KDO23289.1 - 6.9e-11 41.7 0.1 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 KDO23289.1 - 8.3e-10 38.5 0.0 7.7e-05 22.2 0.0 2.6 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KDO23289.1 - 2.8e-05 23.4 0.0 8.2e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KDO23289.1 - 0.0021 18.0 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3130 PF11328.8 KDO23289.1 - 0.048 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 Sec5 PF15469.6 KDO23290.1 - 1.3e-19 70.8 0.0 2.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KDO23290.1 - 0.00033 20.7 0.7 0.0012 18.8 0.3 2.2 1 1 1 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 KDO23290.1 - 0.0027 16.5 1.9 0.0069 15.1 1.9 1.7 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.11 KDO23290.1 - 0.047 13.8 1.0 0.15 12.2 1.0 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Peroxin-3 PF04882.12 KDO23291.1 - 7.3e-14 51.6 0.0 0.00029 20.0 0.1 3.3 1 1 1 3 3 3 3 Peroxin-3 NDUF_B12 PF08122.12 KDO23292.1 - 4.8e-06 26.5 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family FYVE PF01363.21 KDO23293.1 - 1.8e-12 47.2 10.0 3.3e-12 46.4 10.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 KDO23293.1 - 4.6e-06 26.8 4.4 0.0003 21.0 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23293.1 - 0.0014 19.2 0.0 0.024 15.2 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) DUF4686 PF15742.5 KDO23293.1 - 0.0024 17.0 5.6 0.0035 16.6 5.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Ank_4 PF13637.6 KDO23293.1 - 0.01 16.4 0.1 0.12 13.0 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) FYVE_2 PF02318.16 KDO23293.1 - 0.34 11.1 5.8 1 9.6 5.8 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Ank_5 PF13857.6 KDO23294.1 - 2.7e-10 40.3 0.7 0.0028 17.9 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23294.1 - 1.2e-07 32.2 0.0 0.016 15.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO23294.1 - 4.3e-07 29.7 1.3 1.9 9.3 0.0 4.8 4 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KDO23294.1 - 1.1e-05 25.8 1.0 0.63 10.7 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO23294.1 - 0.00028 21.2 7.6 9.2 6.9 0.0 5.6 6 1 0 6 6 6 3 Ankyrin repeat TPR_9 PF13371.6 KDO23294.1 - 6.7 6.9 10.3 5 7.3 0.7 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat DDHD PF02862.17 KDO23295.1 - 2.2e-28 99.9 3.4 2.5e-21 76.9 0.2 3.0 2 1 1 3 3 3 2 DDHD domain PX PF00787.24 KDO23295.1 - 2e-11 43.8 0.0 4.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 PX domain PH PF00169.29 KDO23295.1 - 0.0012 19.3 0.2 3.3 8.3 0.0 2.7 2 0 0 2 2 2 2 PH domain CENP-B_dimeris PF09026.10 KDO23295.1 - 0.026 14.9 11.2 0.079 13.4 11.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.18 KDO23295.1 - 0.49 10.2 5.7 0.85 9.5 5.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SDA1 PF05285.12 KDO23295.1 - 0.57 9.6 3.4 0.85 9.0 3.4 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KDO23295.1 - 0.9 8.8 8.0 1.4 8.1 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 KDO23297.1 - 2.3e-81 273.9 0.0 2.9e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4201 PF13870.6 KDO23298.1 - 5.7e-37 127.2 18.1 5.7e-37 127.2 18.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) PilO PF04350.13 KDO23298.1 - 0.014 15.5 5.0 0.014 15.5 5.0 3.3 2 1 0 3 3 3 0 Pilus assembly protein, PilO FleQ PF06490.11 KDO23298.1 - 0.25 11.8 2.6 12 6.4 0.4 3.2 3 0 0 3 3 3 0 Flagellar regulatory protein FleQ YabA PF06156.13 KDO23298.1 - 1.1 9.9 30.8 0.34 11.6 1.9 4.8 1 1 1 3 3 3 0 Initiation control protein YabA 2OG-FeII_Oxy_3 PF13640.6 KDO23299.1 - 2.4e-08 34.7 0.0 0.0011 19.8 0.0 2.9 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily DUF3573 PF12097.8 KDO23301.1 - 0.00068 18.6 0.0 0.0018 17.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3573) MCC-bdg_PDZ PF10506.9 KDO23301.1 - 0.049 13.6 1.8 5.7 7.0 0.1 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CorA PF01544.18 KDO23301.1 - 0.1 11.9 2.7 0.15 11.3 2.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MIS13 PF08202.11 KDO23301.1 - 0.16 11.2 13.1 0.23 10.7 11.0 1.8 1 1 1 2 2 2 0 Mis12-Mtw1 protein family LCD1 PF09798.9 KDO23301.1 - 2.2 6.7 9.6 3 6.2 9.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CENP-H PF05837.12 KDO23301.1 - 4.7 7.6 13.5 6.7 7.2 12.6 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 KDO23301.1 - 6.1 7.0 18.0 1.6 8.9 11.6 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Allexi_40kDa PF05549.11 KDO23301.1 - 7.8 5.9 6.6 5.6 6.4 4.2 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein Geminin PF07412.12 KDO23302.1 - 0.0027 17.5 1.9 0.0049 16.6 1.9 1.4 1 0 0 1 1 1 1 Geminin Uds1 PF15456.6 KDO23302.1 - 0.0069 16.5 1.0 0.018 15.2 1.0 1.7 1 0 0 1 1 1 1 Up-regulated During Septation UPF0203 PF05254.12 KDO23303.1 - 2.1e-10 40.7 2.7 2.3e-10 40.6 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) BBIP10 PF14777.6 KDO23303.1 - 0.016 14.7 0.2 0.029 13.9 0.2 1.4 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 CX9C PF16860.5 KDO23303.1 - 0.025 14.6 0.7 0.025 14.6 0.7 1.8 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Geminin PF07412.12 KDO23304.1 - 0.02 14.6 1.2 0.04 13.7 0.7 1.8 2 0 0 2 2 2 0 Geminin LUC7 PF03194.15 KDO23304.1 - 0.098 12.3 0.6 0.15 11.7 0.6 1.2 1 0 0 1 1 1 0 LUC7 N_terminus MCC-bdg_PDZ PF10506.9 KDO23306.1 - 0.06 13.4 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Jnk-SapK_ap_N PF09744.9 KDO23306.1 - 0.62 10.3 3.7 1.1 9.5 3.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Metal_resist PF13801.6 KDO23306.1 - 4.3 7.6 15.4 3.6 7.8 0.2 2.7 2 1 0 2 2 2 0 Heavy-metal resistance Atg14 PF10186.9 KDO23308.1 - 0.014 14.5 1.5 0.018 14.2 1.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC23 PF15674.5 KDO23308.1 - 0.04 13.9 0.7 0.04 13.9 0.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 ADIP PF11559.8 KDO23308.1 - 0.057 13.5 8.0 0.1 12.7 8.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Halogen_Hydrol PF10112.9 KDO23308.1 - 0.76 9.8 5.2 4.4 7.3 1.7 2.3 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HR1 PF02185.16 KDO23308.1 - 1.7 8.9 6.6 0.46 10.6 0.6 2.3 2 0 0 2 2 2 0 Hr1 repeat CCDC23 PF15674.5 KDO23309.1 - 0.0028 17.6 2.9 0.0028 17.6 2.9 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 23 bZIP_1 PF00170.21 KDO23309.1 - 0.77 9.9 10.2 0.13 12.4 5.5 2.0 2 0 0 2 2 2 0 bZIP transcription factor NEMO PF11577.8 KDO23309.1 - 2.1 8.4 8.1 3.6 7.7 0.1 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Geminin PF07412.12 KDO23310.1 - 0.0013 18.5 2.5 0.0023 17.7 2.5 1.3 1 0 0 1 1 1 1 Geminin Geminin PF07412.12 KDO23311.1 - 0.015 15.1 0.5 0.03 14.1 0.5 1.4 1 0 0 1 1 1 0 Geminin GOLGA2L5 PF15070.6 KDO23311.1 - 0.017 13.8 4.0 0.026 13.2 4.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF4606 PF15379.6 KDO23313.1 - 0.084 13.1 3.1 0.14 12.4 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) 2OG-FeII_Oxy_3 PF13640.6 KDO23314.1 - 3.4e-08 34.3 0.0 0.0022 18.9 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily SopA PF13981.6 KDO23314.1 - 0.12 12.8 0.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 SopA-like central domain IML1 PF12257.8 KDO23315.1 - 6e-87 291.4 0.0 1.5e-86 290.0 0.0 1.6 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 Flavin_Reduct PF01613.18 KDO23316.1 - 1.7e-11 44.4 0.1 3.1e-11 43.6 0.1 1.3 1 1 0 1 1 1 1 Flavin reductase like domain GRP PF07172.11 KDO23318.1 - 0.14 12.9 19.9 0.22 12.2 19.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family WD40 PF00400.32 KDO23319.1 - 1.9e-12 47.5 9.9 0.011 16.6 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23319.1 - 1e-06 28.9 0.0 0.02 15.2 0.1 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 KDO23319.1 - 1.4e-05 24.9 2.8 0.0005 19.8 2.8 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KDO23319.1 - 0.0089 16.6 0.0 0.041 14.5 0.0 2.2 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Myosin_head PF00063.21 KDO23320.1 - 1.2e-198 661.6 0.0 2.4e-198 660.6 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 KDO23320.1 - 2.7e-11 43.4 0.0 2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 PX domain SHOCT PF09851.9 KDO23320.1 - 0.0012 18.5 0.5 0.0032 17.2 0.5 1.8 1 0 0 1 1 1 1 Short C-terminal domain DZR PF12773.7 KDO23320.1 - 0.011 15.8 0.9 0.027 14.5 0.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon AAA_22 PF13401.6 KDO23320.1 - 0.083 13.2 0.0 0.37 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO23320.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain TF_Zn_Ribbon PF08271.12 KDO23320.1 - 0.12 11.9 1.6 0.29 10.7 1.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KDO23320.1 - 0.12 11.8 3.0 0.33 10.4 3.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain IQ PF00612.27 KDO23320.1 - 9.2 6.4 11.0 0.68 9.9 0.2 3.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif FUSC PF04632.12 KDO23321.1 - 2.8 6.3 4.6 4.6 5.7 4.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_S14 PF00253.21 KDO23322.1 - 9.6e-14 50.9 4.6 1e-13 50.8 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF326 PF03860.16 KDO23322.1 - 0.014 15.4 1.0 0.034 14.1 1.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF326) EF-hand_7 PF13499.6 KDO23323.1 - 0.0033 17.9 0.1 0.0071 16.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO23323.1 - 0.0095 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KDO23323.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 EF hand Vac7 PF12751.7 KDO23323.1 - 6.2 6.2 8.1 2.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Got1 PF04178.12 KDO23324.1 - 7.8e-30 103.6 13.2 1.2e-29 103.0 13.2 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Methyltransf_14 PF08484.11 KDO23324.1 - 0.22 11.3 1.3 0.43 10.4 1.3 1.5 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain DOT1 PF08123.13 KDO23325.1 - 8.6e-26 90.7 0.0 1.3e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 KDO23325.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_31 PF13847.6 KDO23325.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SE PF08491.10 KDO23327.1 - 3.7e-81 272.2 0.0 6e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KDO23327.1 - 2.5e-17 63.2 0.0 2.5e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KDO23327.1 - 1.2e-09 38.3 0.1 1.8e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO23327.1 - 7.3e-06 25.3 0.1 1.3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KDO23327.1 - 2.1e-05 24.7 0.2 5.2e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KDO23327.1 - 8.6e-05 21.8 0.1 0.0017 17.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KDO23327.1 - 0.00022 20.6 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO23327.1 - 0.00035 20.1 0.1 0.00066 19.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KDO23327.1 - 0.00061 20.3 0.1 0.0014 19.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO23327.1 - 0.00062 18.6 0.2 0.0009 18.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KDO23327.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KDO23327.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO23327.1 - 0.0018 17.4 0.1 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KDO23327.1 - 0.01 16.3 0.0 0.15 12.5 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KDO23327.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GDI PF00996.18 KDO23327.1 - 0.055 12.0 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor AlaDh_PNT_C PF01262.21 KDO23327.1 - 0.094 12.0 0.1 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_N PF00732.19 KDO23327.1 - 0.11 11.9 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_2 PF03446.15 KDO23327.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.6 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KDO23327.1 - 0.19 12.0 1.0 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain SNF2_N PF00176.23 KDO23329.1 - 8.7e-60 202.3 2.0 5.5e-57 193.1 1.9 2.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 KDO23329.1 - 6.3e-40 135.7 1.4 1.3e-39 134.7 0.6 2.1 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 KDO23329.1 - 6.1e-19 68.4 0.0 1.5e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO23329.1 - 4.1e-06 26.9 0.0 4.1e-06 26.9 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO23329.1 - 0.012 15.4 0.0 0.062 13.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KDO23329.1 - 0.016 15.4 0.0 0.13 12.5 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF1451 PF07295.11 KDO23329.1 - 0.031 14.3 0.6 0.031 14.3 0.6 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain MobB PF03205.14 KDO23329.1 - 0.032 14.1 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DIM1 PF02966.16 KDO23329.1 - 0.09 12.6 0.5 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Mitosis protein DIM1 DUF896 PF05979.12 KDO23329.1 - 0.12 12.3 2.7 14 5.7 4.3 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) PAT1 PF09770.9 KDO23330.1 - 0.069 11.4 0.8 0.081 11.2 0.0 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BTB PF00651.31 KDO23332.1 - 2.2e-24 85.8 0.2 3.5e-24 85.2 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KDO23332.1 - 1.5e-09 37.9 1.6 5.8e-09 36.0 0.9 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF5543 PF17697.1 KDO23333.1 - 0.13 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5543) Translin PF01997.16 KDO23334.1 - 7.2e-27 94.7 1.5 6.8e-26 91.5 1.5 2.0 1 1 0 1 1 1 1 Translin family DUF3829 PF12889.7 KDO23334.1 - 0.1 12.1 1.3 0.12 11.9 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) ANAPC4 PF12896.7 KDO23335.1 - 1.6e-23 83.3 4.4 2.3e-23 82.8 4.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KDO23335.1 - 1.3e-19 70.2 0.1 4.6e-19 68.5 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO23335.1 - 0.062 14.2 1.2 15 6.7 0.0 4.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Frtz PF11768.8 KDO23335.1 - 0.16 10.3 0.6 1.2 7.4 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ank_2 PF12796.7 KDO23336.1 - 8.4e-13 48.7 0.0 7.7e-07 29.6 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23336.1 - 8.3e-11 42.2 0.2 2.9e-05 24.5 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 KDO23336.1 - 7.8e-09 36.3 0.0 2.7e-08 34.6 0.0 1.9 2 0 0 2 2 1 1 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 KDO23336.1 - 4.1e-06 27.0 0.3 6.8e-05 23.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO23336.1 - 8.6e-06 26.0 0.4 0.00024 21.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat zf-C3HC4_3 PF13920.6 KDO23336.1 - 0.00046 20.0 5.3 0.00087 19.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO23336.1 - 0.0023 17.8 6.3 0.005 16.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO23336.1 - 0.0072 16.3 5.0 0.019 14.9 5.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KDO23336.1 - 0.028 14.3 8.4 0.061 13.2 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO23336.1 - 0.028 14.3 10.0 0.056 13.3 10.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ank_3 PF13606.6 KDO23336.1 - 0.035 14.6 4.8 35 5.4 0.0 4.7 5 0 0 5 5 4 0 Ankyrin repeat zf-RING_2 PF13639.6 KDO23336.1 - 0.05 14.0 7.3 0.11 12.8 7.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KDO23336.1 - 0.066 13.3 3.5 0.17 11.9 3.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger CCDC144C PF14915.6 KDO23337.1 - 0.89 8.6 9.7 5 6.1 5.7 2.3 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF2058 PF09831.9 KDO23337.1 - 4 7.6 12.7 0.079 13.1 4.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Pkinase PF00069.25 KDO23338.1 - 4.1e-64 216.5 0.0 6.4e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23338.1 - 1.9e-31 109.3 0.0 2.8e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KDO23338.1 - 2.9e-23 81.7 0.0 4.9e-11 42.6 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KDO23338.1 - 4.8e-07 29.4 0.0 2.6e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO23338.1 - 3.8e-06 27.0 0.5 3.8e-06 27.0 0.5 2.6 2 2 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO23338.1 - 3.4e-05 22.8 0.0 5.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO23338.1 - 6.3e-05 22.4 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO23338.1 - 0.0012 18.5 0.0 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KDO23338.1 - 0.0025 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 EF-hand_8 PF13833.6 KDO23338.1 - 0.0051 16.6 0.1 0.021 14.6 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO23338.1 - 0.03 13.8 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KDO23338.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF3104 PF11302.8 KDO23338.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) AAA_6 PF12774.7 KDO23339.1 - 5.8e-14 51.8 0.0 5.5e-06 25.6 0.0 3.0 2 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO23339.1 - 4e-13 49.2 0.0 2.4e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 ABC_tran PF00005.27 KDO23339.1 - 6.8e-08 33.1 0.0 0.012 16.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KDO23339.1 - 7.9e-08 31.9 0.1 0.013 15.2 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 KDO23339.1 - 1.9e-06 27.5 0.1 0.065 12.8 0.0 4.2 3 1 0 3 3 3 2 P-loop containing dynein motor region AAA_30 PF13604.6 KDO23339.1 - 4.7e-06 26.4 0.0 0.21 11.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KDO23339.1 - 2.2e-05 23.8 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) T2SSE PF00437.20 KDO23339.1 - 0.00015 20.9 0.0 0.73 8.8 0.1 2.8 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 KDO23339.1 - 0.00075 20.1 1.3 1.9 8.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KDO23339.1 - 0.00095 19.1 0.0 0.71 9.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KDO23339.1 - 0.001 19.3 1.4 1.4 9.2 0.0 4.6 4 1 1 5 5 3 1 AAA domain Fez1 PF06818.15 KDO23339.1 - 0.0012 19.4 2.5 0.7 10.3 0.1 2.4 2 0 0 2 2 2 2 Fez1 AAA_28 PF13521.6 KDO23339.1 - 0.0021 18.3 0.0 0.35 11.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KDO23339.1 - 0.0066 16.5 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO23339.1 - 0.014 15.6 0.0 0.34 11.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KDO23339.1 - 0.015 15.2 0.7 3.6 7.5 0.1 3.0 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KDO23339.1 - 0.016 15.3 0.0 5.5 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO23339.1 - 0.021 15.2 28.3 0.038 14.4 0.0 7.3 7 1 0 7 7 7 0 AAA ATPase domain AAA_19 PF13245.6 KDO23339.1 - 0.034 14.5 0.0 16 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KDO23339.1 - 0.042 13.6 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 KDO23339.1 - 0.061 12.9 2.0 0.47 10.0 0.0 2.9 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KDO23339.1 - 0.063 13.3 0.1 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KDO23339.1 - 0.066 13.0 0.0 5.6 6.7 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 KDO23339.1 - 0.066 12.6 0.2 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KDO23339.1 - 0.084 12.2 0.1 5.2 6.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 KDO23339.1 - 0.093 12.7 0.3 2.1 8.4 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KDO23339.1 - 0.094 13.1 0.0 3.8 8.0 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KDO23339.1 - 0.12 11.9 0.0 19 4.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO23339.1 - 0.13 11.5 0.3 9.7 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 KDO23339.1 - 0.14 12.1 0.0 24 4.8 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KDO23339.1 - 0.15 11.8 0.0 23 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KDO23339.1 - 0.15 11.8 0.0 2.3 7.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system BRE1 PF08647.11 KDO23339.1 - 0.41 10.8 2.4 15 5.8 1.7 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Filament PF00038.21 KDO23339.1 - 1.7 8.1 4.3 3.2 7.3 1.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein ABC_tran_CTD PF16326.5 KDO23339.1 - 2.8 8.2 7.5 19 5.6 1.6 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-rbx1 PF12678.7 KDO23340.1 - 1.3e-25 89.4 12.9 1.8e-25 89.0 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO23340.1 - 3.2e-18 65.6 9.9 3.9e-18 65.3 9.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KDO23340.1 - 1.3e-06 28.6 14.8 5.5e-05 23.4 14.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO23340.1 - 3.9e-05 23.4 3.1 3.9e-05 23.4 3.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO23340.1 - 0.0008 19.2 11.9 0.014 15.2 11.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO23340.1 - 0.072 13.0 11.0 0.29 11.0 4.7 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KDO23340.1 - 0.12 12.6 8.6 1.3 9.3 9.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KDO23340.1 - 0.17 11.7 15.8 17 5.2 15.8 2.5 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KDO23340.1 - 0.23 11.1 15.4 38 4.0 15.4 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KDO23340.1 - 0.28 11.2 7.9 1.1 9.3 7.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KDO23340.1 - 5.9 6.9 12.7 47 4.1 12.7 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KDO23340.1 - 9.4 6.5 9.7 0.63 10.3 0.7 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING CxC1 PF18802.1 KDO23341.1 - 0.069 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases HnRNPA1 PF11627.8 KDO23341.1 - 0.1 12.8 3.2 0.18 12.0 3.2 1.4 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 Hep_core_N PF08290.11 KDO23342.1 - 0.11 12.5 2.5 0.43 10.6 0.9 2.5 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger DUF2181 PF10223.9 KDO23343.1 - 2e-50 171.5 0.2 2.5e-50 171.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Ank_2 PF12796.7 KDO23344.1 - 6.7e-25 87.5 9.1 4.2e-05 24.1 0.3 5.3 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23344.1 - 7.3e-25 87.0 12.5 1.4e-05 25.6 0.1 7.6 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23344.1 - 3.8e-19 68.5 17.8 0.049 14.0 0.0 10.0 3 2 7 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23344.1 - 5.5e-15 54.0 7.7 7.7 7.4 0.0 10.0 10 0 0 10 10 10 4 Ankyrin repeat DUF5049 PF16468.5 KDO23344.1 - 9.3e-05 22.2 0.9 17 5.4 0.0 5.9 4 2 2 6 6 6 1 Domain of unknown function (DUF5049) DUF3322 PF11795.8 KDO23344.1 - 0.094 12.7 0.2 42 4.1 0.0 3.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DsrC PF04358.13 KDO23344.1 - 0.12 12.9 0.0 12 6.4 0.0 2.9 1 1 1 2 2 2 0 DsrC like protein Ank PF00023.30 KDO23344.1 - 0.34 11.4 9.5 2.5e+02 2.4 0.1 7.3 4 3 2 6 6 6 0 Ankyrin repeat Aa_trans PF01490.18 KDO23345.1 - 6.4e-27 94.3 26.0 7.7e-27 94.0 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SR1P PF13790.6 KDO23345.1 - 0.33 11.1 2.5 0.68 10.1 2.5 1.5 1 0 0 1 1 1 0 SR1 protein IQ PF00612.27 KDO23347.1 - 1.5e-14 52.3 63.4 0.0016 18.0 3.0 8.7 7 0 0 7 7 7 5 IQ calmodulin-binding motif TPR_8 PF13181.6 KDO23347.1 - 9.9e-05 22.3 0.1 0.5 10.7 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO23347.1 - 0.0022 18.6 7.8 0.0072 17.0 6.7 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO23347.1 - 0.018 15.5 16.0 0.091 13.3 0.9 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec7_N PF12783.7 KDO23347.1 - 0.35 10.8 1.7 30 4.5 0.1 2.9 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.6 KDO23347.1 - 2.5 8.4 5.0 1e+02 3.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KDO23347.1 - 3.6 7.7 6.3 1.6 8.9 0.5 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Gal-bind_lectin PF00337.22 KDO23348.1 - 3.3e-12 46.1 0.0 5.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 KDO23348.1 - 6.7e-09 35.4 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp_protease PF09668.10 KDO23349.1 - 1.6e-57 192.6 0.2 2.5e-57 192.0 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KDO23349.1 - 1.5e-22 80.0 0.0 3.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KDO23349.1 - 1.3e-10 41.8 0.0 3.3e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 KDO23349.1 - 1.9e-09 37.1 0.0 3.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO23349.1 - 2.1e-06 27.5 0.1 5.4e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KDO23349.1 - 2.1e-05 24.3 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 KDO23349.1 - 0.00013 21.7 0.0 0.00034 20.4 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 KDO23349.1 - 0.015 15.1 0.1 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 UBA-like domain RVP PF00077.20 KDO23349.1 - 0.061 13.6 0.0 0.26 11.6 0.0 2.2 1 1 1 2 2 2 0 Retroviral aspartyl protease Ubiquitin_5 PF18037.1 KDO23349.1 - 0.1 12.9 0.2 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain His_Phos_2 PF00328.22 KDO23350.1 - 1.5e-15 57.4 0.5 4.7e-12 46.0 0.5 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cir_N PF10197.9 KDO23351.1 - 2.8e-08 33.8 7.2 2.8e-08 33.8 7.2 4.1 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR CSRNP_N PF16019.5 KDO23351.1 - 7.7 6.4 9.2 6 6.7 4.0 2.5 2 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus WD40 PF00400.32 KDO23353.1 - 7.1e-24 83.6 10.7 3.1e-06 27.8 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KDO23353.1 - 3e-11 42.7 0.1 6.5e-05 21.8 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KDO23353.1 - 4.7e-11 42.8 0.0 2.3e-06 27.8 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO23353.1 - 5.2e-09 35.5 2.4 0.00012 21.2 0.1 3.6 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KDO23353.1 - 0.0041 16.1 0.6 0.97 8.3 0.0 3.0 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 KDO23353.1 - 0.019 14.7 0.5 3.4 7.3 0.1 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split FOP_dimer PF09398.10 KDO23354.1 - 9.9e-13 48.2 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KDO23354.1 - 4.6e-12 44.7 0.1 6.9e-12 44.2 0.1 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 KDO23354.1 - 0.0021 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 LisH PIH1_CS PF18201.1 KDO23355.1 - 1.6e-07 31.6 0.0 3.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain Exo_endo_phos PF03372.23 KDO23357.1 - 9.6e-72 241.3 5.8 2.3e-71 240.0 5.8 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family fn3 PF00041.21 KDO23357.1 - 1.9e-12 47.4 0.0 6.4e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO23357.1 - 5.6e-06 26.8 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain LRR_9 PF14580.6 KDO23358.1 - 2.1e-14 53.4 0.0 3.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KDO23358.1 - 1.2e-10 41.0 0.4 8.6e-07 28.6 0.2 3.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO23358.1 - 1.2e-05 25.5 2.3 0.079 13.4 0.0 3.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO23360.1 - 2.9e-14 52.6 6.1 4.6e-08 32.7 1.0 4.4 2 1 3 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KDO23360.1 - 2.1e-09 37.5 8.8 2.5e-05 24.5 0.1 4.5 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO23360.1 - 8.7e-07 29.3 13.1 2e-06 28.1 13.1 1.7 1 0 0 1 1 1 1 LNR domain LRR_9 PF14580.6 KDO23360.1 - 0.0036 16.8 0.1 0.0068 15.9 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KDO23360.1 - 0.17 12.5 1.2 1.2e+02 3.9 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO23361.1 - 1.8e-07 30.8 1.1 0.00088 19.0 1.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat Notch PF00066.17 KDO23361.1 - 0.0001 22.7 13.5 0.0001 22.7 13.5 2.3 2 0 0 2 2 2 1 LNR domain LRR_4 PF12799.7 KDO23361.1 - 0.00026 21.3 0.2 0.21 12.1 0.4 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) CFC PF09443.10 KDO23361.1 - 0.0064 16.3 0.6 0.019 14.8 0.6 1.8 1 0 0 1 1 1 1 Cripto_Frl-1_Cryptic (CFC) Fcf2 PF08698.11 KDO23362.1 - 6e-34 116.3 3.3 2.3e-33 114.5 3.3 2.0 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing rRNA_processing PF08524.11 KDO23363.1 - 1.3e-10 41.4 12.5 2.6e-10 40.5 12.5 1.4 1 1 0 1 1 1 1 rRNA processing DUF4456 PF14644.6 KDO23363.1 - 0.018 14.7 3.0 0.025 14.3 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) PP-binding PF00550.25 KDO23364.1 - 2.4e-10 40.6 0.3 3.2e-10 40.2 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KDO23364.1 - 0.00076 19.7 0.6 0.00096 19.3 0.6 1.2 1 0 0 1 1 1 1 Acyl-carrier Thoc2 PF11732.8 KDO23364.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Porin_3 PF01459.22 KDO23365.1 - 2e-30 106.2 8.6 3.3e-16 59.5 2.6 2.0 1 1 1 2 2 2 2 Eukaryotic porin CinA PF02464.17 KDO23366.1 - 1.6e-06 27.8 0.4 3.4e-06 26.7 0.4 1.5 1 0 0 1 1 1 1 Competence-damaged protein Arf PF00025.21 KDO23367.1 - 7.6e-36 123.2 0.0 9.4e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO23367.1 - 4.1e-11 43.1 0.0 5.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO23367.1 - 6.2e-10 38.9 0.0 8.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KDO23367.1 - 3.3e-07 29.9 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO23367.1 - 4.2e-06 26.2 0.1 0.0005 19.3 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO23367.1 - 5.5e-06 26.4 0.0 8.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO23367.1 - 0.00012 21.7 0.0 0.032 13.8 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KDO23367.1 - 0.00083 19.0 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KDO23367.1 - 0.00085 19.8 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KDO23367.1 - 0.0014 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KDO23367.1 - 0.0018 18.7 0.0 0.0031 17.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KDO23367.1 - 0.0054 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO23367.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO23367.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO23367.1 - 0.013 15.4 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 KDO23367.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 KDO23367.1 - 0.036 14.0 0.2 0.097 12.6 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KDO23367.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO23367.1 - 0.084 13.2 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KDO23367.1 - 0.085 12.4 0.1 0.19 11.3 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KDO23367.1 - 0.092 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KDO23367.1 - 0.11 12.3 0.6 6.9 6.4 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KDO23367.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KDO23367.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KDO23368.1 - 7.2e-68 227.5 0.0 8.6e-68 227.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO23368.1 - 4.2e-15 56.0 0.1 5.7e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO23368.1 - 1e-12 47.9 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KDO23368.1 - 2.1e-12 46.9 0.0 2.5e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO23368.1 - 2.3e-11 43.5 1.1 1.7e-08 34.0 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KDO23368.1 - 2e-09 37.2 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO23368.1 - 1.4e-05 25.2 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO23368.1 - 0.002 17.7 0.1 0.0086 15.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.18 KDO23368.1 - 0.012 15.0 0.1 0.017 14.4 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 KDO23368.1 - 0.16 11.5 0.5 1.6 8.3 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KDO23369.1 - 1.3e-44 151.7 0.1 1.1e-43 148.7 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO23369.1 - 5.4e-08 33.1 0.0 8.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO23369.1 - 3.1e-07 30.0 0.0 6e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KDO23369.1 - 6.5e-06 25.8 0.0 3.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Ras family G-alpha PF00503.20 KDO23369.1 - 0.01 15.0 0.1 1.5 7.9 0.0 2.8 1 1 2 3 3 3 0 G-protein alpha subunit TniB PF05621.11 KDO23369.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KDO23369.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO23369.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SAM_PNT PF02198.16 KDO23369.1 - 0.13 12.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain ER PF01133.17 KDO23370.1 - 7.1e-42 141.4 0.5 8e-42 141.2 0.5 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Skp1_POZ PF03931.15 KDO23371.1 - 1.7e-12 47.3 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KDO23371.1 - 1.5e-05 25.2 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Transmemb_17 PF09799.9 KDO23372.1 - 4.3e-19 69.1 9.4 5.7e-19 68.7 9.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein Ras PF00071.22 KDO23373.1 - 7.3e-32 110.2 0.0 8.6e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23373.1 - 1.9e-13 50.7 0.0 2.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23373.1 - 1.7e-05 24.3 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KDO23373.1 - 0.00042 20.2 0.1 0.027 14.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KDO23373.1 - 0.00055 19.4 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KDO23373.1 - 0.0056 16.4 0.0 0.056 13.2 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KDO23373.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO23373.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KDO23373.1 - 0.013 15.4 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KDO23373.1 - 0.02 15.2 0.0 0.034 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO23373.1 - 0.031 14.4 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KDO23373.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KDO23373.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin ubiquitin PF00240.23 KDO23374.1 - 1.7e-26 91.7 0.7 1.9e-26 91.6 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO23374.1 - 3.5e-14 52.4 0.7 3.9e-14 52.2 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KDO23374.1 - 5.7e-06 26.6 0.2 6.4e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO23374.1 - 6e-06 26.3 0.1 1.4e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO23374.1 - 3.2e-05 24.3 0.2 0.00012 22.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KDO23374.1 - 0.0045 17.5 0.0 0.0055 17.2 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Blt1 PF12754.7 KDO23374.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain Peptidase_C12 PF01088.21 KDO23375.1 - 2e-67 227.1 0.0 3.2e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KDO23375.1 - 1.2e-21 76.3 0.5 2.3e-21 75.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases TPR_MLP1_2 PF07926.12 KDO23376.1 - 0.0095 16.0 4.8 0.028 14.5 3.1 2.6 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KDO23376.1 - 0.019 15.2 8.7 0.35 11.2 4.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 KDO23376.1 - 0.029 14.7 6.1 1.3 9.4 0.8 4.0 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 KDO23376.1 - 0.042 14.3 3.6 3.9 8.0 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KDO23376.1 - 0.049 14.0 2.5 0.82 10.1 0.0 3.1 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Hemagglutinin PF00509.18 KDO23376.1 - 0.053 11.9 2.4 0.097 11.1 2.4 1.3 1 0 0 1 1 1 0 Haemagglutinin EF-G-binding_N PF07299.11 KDO23376.1 - 0.073 13.6 0.2 0.44 11.1 0.2 2.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Cas3_C PF18395.1 KDO23376.1 - 0.13 12.8 1.0 2 9.0 0.3 2.9 2 0 0 2 2 2 0 Cas3 C-terminal domain DUF4446 PF14584.6 KDO23376.1 - 0.23 11.4 1.4 12 5.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF948 PF06103.11 KDO23376.1 - 0.34 11.2 4.7 0.89 9.8 0.0 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KDO23376.1 - 0.38 10.8 6.0 4.8 7.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KDO23376.1 - 0.45 10.7 8.0 8.1 6.6 3.7 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KDO23376.1 - 1 9.4 15.2 2.1 8.4 0.1 3.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 KDO23376.1 - 1.2 9.2 7.6 16 5.5 2.3 3.1 3 1 0 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 KDO23376.1 - 4.1 7.9 9.6 40 4.8 2.6 3.6 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 KDO23376.1 - 9.9 5.3 7.3 31 3.7 0.0 2.8 2 1 2 4 4 4 0 TMPIT-like protein LRR_8 PF13855.6 KDO23377.1 - 7.6e-10 38.4 0.1 6e-05 22.7 0.0 3.0 3 1 2 5 5 5 3 Leucine rich repeat Notch PF00066.17 KDO23377.1 - 5.8e-05 23.5 6.8 0.00018 21.9 6.8 1.9 1 0 0 1 1 1 1 LNR domain LRR_4 PF12799.7 KDO23377.1 - 0.0093 16.4 0.2 1.8 9.1 0.1 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) WD40 PF00400.32 KDO23378.1 - 0.0012 19.7 5.8 0.31 12.0 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Ras PF00071.22 KDO23379.1 - 3.2e-62 208.9 0.2 4.4e-62 208.5 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23379.1 - 6.5e-36 123.2 0.1 1.1e-35 122.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23379.1 - 9e-15 54.6 0.2 2.1e-14 53.3 0.1 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO23379.1 - 4.7e-07 29.9 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO23379.1 - 3.9e-05 23.6 0.2 0.019 14.9 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO23379.1 - 5.6e-05 22.8 0.1 0.00022 20.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO23379.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KDO23379.1 - 0.0027 18.1 0.1 0.0045 17.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO23379.1 - 0.0054 17.0 0.0 0.042 14.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KDO23379.1 - 0.0095 16.5 0.1 0.024 15.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 KDO23379.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KDO23379.1 - 0.014 14.9 0.1 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KDO23379.1 - 0.026 14.1 0.1 0.12 11.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KDO23379.1 - 0.031 14.3 0.0 0.081 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO23379.1 - 0.032 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain YtzH PF14165.6 KDO23379.1 - 0.038 14.4 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 YtzH-like protein Herpes_glycop_H PF02489.16 KDO23379.1 - 0.052 12.1 0.1 0.053 12.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain AAA_5 PF07728.14 KDO23379.1 - 0.058 13.4 0.0 0.34 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KDO23379.1 - 0.063 12.5 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain TniB PF05621.11 KDO23379.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein DUF2868 PF11067.8 KDO23379.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TusA PF01206.17 KDO23379.1 - 0.12 12.2 0.0 8.5 6.3 0.0 2.7 3 0 0 3 3 3 0 Sulfurtransferase TusA AAA_21 PF13304.6 KDO23379.1 - 0.24 11.2 0.5 0.28 11.0 0.5 1.3 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PAF-AH_p_II PF03403.13 KDO23380.1 - 0.037 12.5 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4059 PF13268.6 KDO23380.1 - 0.038 14.4 0.8 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Acyl_transf_3 PF01757.22 KDO23381.1 - 7.8e-22 77.8 35.5 8.8e-22 77.6 33.0 2.2 1 1 1 2 2 2 2 Acyltransferase family ApoL PF05461.11 KDO23381.1 - 0.097 12.0 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Apolipoprotein L TMEM51 PF15345.6 KDO23382.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM154 PF15102.6 KDO23382.1 - 0.005 16.8 0.2 0.045 13.7 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family FAM176 PF14851.6 KDO23382.1 - 0.0085 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 FAM176 family DUF202 PF02656.15 KDO23382.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF202) OAD_gamma PF04277.13 KDO23382.1 - 0.34 11.5 1.7 1 10.0 0.0 2.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF3246 PF11596.8 KDO23382.1 - 4.1 6.8 17.9 4.9 6.5 7.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3246) HALZ PF02183.18 KDO23384.1 - 0.11 12.7 14.4 0.81 10.0 0.0 4.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper zf-RING_2 PF13639.6 KDO23385.1 - 1.8e-09 37.8 7.7 3.2e-09 37.0 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO23385.1 - 3.2e-09 36.5 6.1 5.1e-09 35.8 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO23385.1 - 2.3e-08 33.7 6.7 3.7e-08 33.1 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO23385.1 - 1.3e-07 31.4 5.9 1.9e-07 30.8 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO23385.1 - 3e-05 24.2 9.1 0.00016 21.9 9.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KDO23385.1 - 0.00015 21.8 6.0 0.00028 21.0 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO23385.1 - 0.00044 20.2 2.5 0.00082 19.3 2.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO23385.1 - 0.00054 19.8 6.4 0.001 18.9 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO23385.1 - 0.003 17.6 1.9 0.0053 16.9 1.9 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KDO23385.1 - 0.025 14.3 4.5 0.048 13.4 4.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KDO23385.1 - 0.028 14.4 7.0 0.054 13.5 7.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RskA PF10099.9 KDO23385.1 - 0.049 13.9 0.8 1.8 8.8 2.1 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA zf-P11 PF03854.14 KDO23385.1 - 0.069 12.8 3.1 0.15 11.7 3.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger RICTOR_phospho PF14665.6 KDO23385.1 - 0.14 12.5 0.1 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site zf-ANAPC11 PF12861.7 KDO23385.1 - 0.59 10.2 4.0 1.3 9.1 4.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KDO23385.1 - 0.83 9.5 6.7 2.3 8.1 6.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TMEM154 PF15102.6 KDO23387.1 - 0.27 11.2 12.7 0.15 11.9 7.3 3.1 2 1 0 2 2 2 0 TMEM154 protein family DUF4366 PF14283.6 KDO23387.1 - 0.29 11.2 3.8 2 8.4 3.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SKG6 PF08693.10 KDO23388.1 - 3e-05 23.3 1.5 5.3e-05 22.5 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KDO23388.1 - 0.021 14.8 1.1 0.046 13.6 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF4448 PF14610.6 KDO23388.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rab5ip PF07019.12 KDO23388.1 - 0.15 12.6 0.6 0.25 11.9 0.6 1.2 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) EphA2_TM PF14575.6 KDO23388.1 - 0.18 12.7 0.0 0.33 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM171 PF15471.6 KDO23388.1 - 3 6.8 0.0 3 6.8 0.0 3.1 2 1 1 3 3 3 0 Transmembrane protein family 171 AAA_28 PF13521.6 KDO23390.1 - 0.083 13.1 0.5 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_M24 PF00557.24 KDO23391.1 - 3e-32 112.0 0.0 4.3e-32 111.5 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 adh_short PF00106.25 KDO23392.1 - 3.7e-34 117.9 0.1 6.8e-34 117.0 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO23392.1 - 1.1e-27 97.1 0.2 1.4e-27 96.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO23392.1 - 2.8e-05 24.1 0.1 0.0096 15.8 0.0 2.1 2 0 0 2 2 2 2 KR domain Shikimate_DH PF01488.20 KDO23392.1 - 0.00076 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KDO23392.1 - 0.062 13.2 0.5 0.13 12.1 0.2 1.7 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 KDO23393.1 - 4.3e-32 111.5 0.0 7e-32 110.8 0.0 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Spc7 PF08317.11 KDO23394.1 - 0.00038 19.4 89.2 0.0009 18.2 9.2 5.9 2 2 4 6 6 6 3 Spc7 kinetochore protein ADIP PF11559.8 KDO23394.1 - 0.0047 17.0 5.3 0.0047 17.0 5.3 8.7 5 2 3 8 8 8 5 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 KDO23394.1 - 0.21 11.7 56.3 2.3 8.4 0.2 10.3 8 2 1 9 9 9 0 bZIP transcription factor Sfi1_C PF10638.9 KDO23394.1 - 5 7.9 10.1 0.14 12.9 1.1 3.2 3 0 0 3 3 3 0 Spindle body associated protein C-terminus Surfac_D-trimer PF09006.11 KDO23395.1 - 0.75 9.7 2.5 13 5.8 0.1 4.5 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Kinesin PF00225.23 KDO23396.1 - 2.8e-35 121.8 0.0 1.4e-29 103.0 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KDO23396.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding T4_baseplate PF12322.8 KDO23396.1 - 0.052 13.0 1.1 6.1 6.3 0.0 2.8 2 1 0 2 2 2 0 T4 bacteriophage base plate protein UBN_AB PF14075.6 KDO23396.1 - 0.71 9.6 7.6 2.1 8.0 7.6 1.8 1 0 0 1 1 1 0 Ubinuclein conserved middle domain CH PF00307.31 KDO23397.1 - 2.6e-21 75.8 0.4 4.3e-10 39.8 0.0 3.8 3 1 0 3 3 3 2 Calponin homology (CH) domain ASH PF15780.5 KDO23397.1 - 7.7e-15 54.9 0.0 1.9e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin IQ PF00612.27 KDO23397.1 - 4.1e-13 47.9 91.9 2.5e-05 23.7 0.0 16.7 16 0 0 16 16 16 9 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 KDO23397.1 - 8.9e-10 38.3 0.2 0.00075 19.3 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain TMEM131_like PF12371.8 KDO23397.1 - 7.9e-05 22.8 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Transmembrane protein 131-like Novirhabdo_Nv PF05554.11 KDO23397.1 - 0.046 13.5 0.1 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein HSF_DNA-bind PF00447.17 KDO23399.1 - 6.1e-20 71.6 2.2 8.7e-20 71.1 2.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Glycogen_syn PF05693.13 KDO23399.1 - 0.095 11.2 0.1 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 Glycogen synthase HTH_30 PF13556.6 KDO23399.1 - 0.097 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain LSM PF01423.22 KDO23400.1 - 5.8e-22 77.2 0.2 7e-22 76.9 0.2 1.0 1 0 0 1 1 1 1 LSM domain Ribonuc_L-PSP PF01042.21 KDO23401.1 - 1.6e-26 92.7 0.1 1.7e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.17 KDO23401.1 - 0.0052 17.1 0.1 0.0089 16.3 0.1 1.4 1 0 0 1 1 1 1 BON domain Ribonuc_L-PSP PF01042.21 KDO23402.1 - 1.1e-24 86.7 0.2 1.6e-24 86.3 0.2 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.17 KDO23402.1 - 0.00086 19.6 0.4 0.0016 18.7 0.4 1.5 1 0 0 1 1 1 1 BON domain Aminotran_3 PF00202.21 KDO23403.1 - 1.4e-110 369.8 0.0 1.6e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Thioredoxin PF00085.20 KDO23404.1 - 3.8e-24 84.6 0.1 4.4e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO23404.1 - 1.3e-05 25.6 0.2 0.00039 20.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO23404.1 - 2.1e-05 24.6 0.0 3.6e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KDO23404.1 - 4e-05 23.4 0.0 4.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KDO23404.1 - 0.0014 18.5 0.1 0.0026 17.7 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KDO23404.1 - 0.0016 18.7 0.0 0.05 13.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 KDO23404.1 - 0.003 17.3 0.1 0.034 13.9 0.0 2.0 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 KDO23404.1 - 0.0035 17.5 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 KDO23404.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KDO23405.1 - 1.2e-19 70.2 0.0 1.4e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO23405.1 - 6.1e-06 26.7 0.0 2.6e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KDO23405.1 - 8.9e-05 22.4 0.0 9.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KDO23405.1 - 0.00017 21.1 0.0 0.00019 20.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KDO23405.1 - 0.00057 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 KDO23405.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 KDO23405.1 - 0.013 15.7 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DUF3318 PF11780.8 KDO23405.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Thioredoxin_8 PF13905.6 KDO23405.1 - 0.015 15.6 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 KDO23405.1 - 0.043 13.7 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin PF00085.20 KDO23406.1 - 3.3e-23 81.6 0.0 3.5e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO23406.1 - 1.2e-07 32.1 0.3 8.6e-07 29.4 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KDO23406.1 - 5.8e-05 23.0 0.0 6.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KDO23406.1 - 0.00014 22.1 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KDO23406.1 - 0.00022 21.0 0.0 0.0011 18.7 0.0 1.8 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 KDO23406.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DIM1 PF02966.16 KDO23406.1 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 KDO23406.1 - 0.0042 17.2 0.1 0.008 16.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KDO23406.1 - 0.0055 16.1 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KDO23406.1 - 0.026 14.3 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF953 PF06110.11 KDO23406.1 - 0.15 11.6 0.1 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) SpoU_methylase PF00588.19 KDO23407.1 - 6.1e-30 104.3 0.0 6.8e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Sdh_cyt PF01127.22 KDO23408.1 - 5.7e-11 42.5 0.1 7.3e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Phage_holin_2_4 PF16082.5 KDO23408.1 - 4 7.2 6.8 0.49 10.2 1.7 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Profilin PF00235.19 KDO23409.1 - 0.00016 22.0 0.0 0.00018 21.8 0.0 1.1 1 0 0 1 1 1 1 Profilin B9-C2 PF07162.11 KDO23410.1 - 2.1e-42 145.2 0.1 2.4e-42 145.0 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Cmc1 PF08583.10 KDO23411.1 - 6e-13 48.6 2.1 6.1e-13 48.6 1.6 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KDO23411.1 - 0.029 14.6 0.7 2.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PX PF00787.24 KDO23414.1 - 7.9e-10 38.7 0.5 1.5e-09 37.8 0.5 1.4 1 0 0 1 1 1 1 PX domain Cwf_Cwc_15 PF04889.12 KDO23416.1 - 0.39 10.4 5.5 0.46 10.2 5.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CHAT PF12770.7 KDO23419.1 - 1.4e-07 31.2 0.2 1.4e-07 31.2 0.2 1.7 2 0 0 2 2 2 1 CHAT domain NACHT PF05729.12 KDO23419.1 - 6.6e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KDO23419.1 - 0.00023 21.6 0.0 0.0012 19.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO23419.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO23419.1 - 0.0085 16.5 0.3 0.085 13.2 0.4 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KDO23419.1 - 0.015 14.9 0.6 0.059 12.9 0.6 2.0 1 1 0 1 1 1 0 AAA domain DYW_deaminase PF14432.6 KDO23419.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases AAA_18 PF13238.6 KDO23419.1 - 0.18 12.4 0.0 0.6 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain MtN3_slv PF03083.16 KDO23421.1 - 8.8e-32 109.0 7.0 2.3e-16 59.6 0.2 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 KDO23421.1 - 0.014 15.2 0.9 5.6 6.8 0.6 2.7 2 0 0 2 2 2 0 PQ loop repeat LAB_N PF07578.11 KDO23421.1 - 0.099 12.7 1.9 0.62 10.2 0.1 2.5 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain PRA1 PF03208.19 KDO23421.1 - 0.72 9.5 8.3 0.18 11.4 3.0 2.2 2 0 0 2 2 2 0 PRA1 family protein FKBP_C PF00254.28 KDO23422.1 - 5.2e-28 97.2 0.0 6.9e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PIH1 PF08190.12 KDO23424.1 - 5e-31 107.4 0.0 1.2e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KDO23424.1 - 4.7e-16 59.0 0.0 1.7e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain PRCC PF10253.9 KDO23424.1 - 0.048 14.5 11.4 1.3 9.8 0.4 2.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Hamartin PF04388.12 KDO23424.1 - 0.23 10.1 14.4 0.024 13.4 6.0 2.1 2 0 0 2 2 2 0 Hamartin protein Aldedh PF00171.22 KDO23425.1 - 7.1e-79 265.5 0.0 9.1e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BBS2_C PF14782.6 KDO23426.1 - 4e-135 450.9 1.2 8.1e-134 446.6 0.0 2.5 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KDO23426.1 - 9.2e-42 141.5 0.3 4.7e-40 136.0 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 KDO23426.1 - 1.6e-37 127.6 0.6 3.9e-36 123.1 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 KDO23426.1 - 9.2e-05 21.6 3.6 0.14 11.1 0.0 3.8 2 1 1 4 4 4 2 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 KDO23426.1 - 0.0011 19.1 2.4 0.0025 17.9 0.1 2.7 3 0 0 3 3 3 1 FG-GAP repeat VCBS PF13517.6 KDO23426.1 - 0.0014 19.1 0.8 0.081 13.5 0.0 2.9 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 KDO23426.1 - 0.028 14.0 0.0 0.41 10.2 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain ARL2_Bind_BART PF11527.8 KDO23427.1 - 4.3e-21 75.2 8.2 5.6e-21 74.8 8.2 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Cofac_haem_bdg PF04187.13 KDO23427.1 - 0.019 15.0 1.0 0.021 14.8 0.3 1.5 1 1 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN ABC_membrane PF00664.23 KDO23428.1 - 3.5e-56 190.9 37.5 1.4e-32 113.5 16.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO23428.1 - 6.5e-49 166.0 0.0 5.5e-29 101.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO23428.1 - 8.3e-11 41.7 5.7 0.0055 16.2 0.8 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO23428.1 - 1.3e-06 28.1 1.6 0.028 14.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO23428.1 - 2e-06 27.8 0.1 0.0049 16.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO23428.1 - 2.5e-06 27.5 1.0 0.019 15.0 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KDO23428.1 - 5.4e-06 27.0 0.3 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KDO23428.1 - 6.2e-06 26.5 0.0 0.13 12.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KDO23428.1 - 1.1e-05 25.4 1.2 0.12 12.1 0.0 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO23428.1 - 1.2e-05 25.8 0.2 0.053 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KDO23428.1 - 0.00013 22.2 4.0 0.024 14.8 0.2 3.3 2 1 1 3 3 3 1 Helicase HerA, central domain T2SSE PF00437.20 KDO23428.1 - 0.00043 19.4 0.1 0.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 KDO23428.1 - 0.0005 19.7 2.8 0.22 11.1 0.1 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KDO23428.1 - 0.0012 18.9 0.7 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 KDO23428.1 - 0.0026 17.6 0.2 0.31 10.7 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KDO23428.1 - 0.0031 17.3 0.5 2.5 7.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KDO23428.1 - 0.0038 16.7 0.3 3 7.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KDO23428.1 - 0.0044 16.2 0.1 1.8 7.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KDO23428.1 - 0.01 15.6 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KDO23428.1 - 0.017 15.6 0.0 2.1 8.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KDO23428.1 - 0.028 13.6 2.3 4.1 6.5 0.4 3.0 3 1 0 3 3 2 0 NB-ARC domain ATP_bind_1 PF03029.17 KDO23428.1 - 0.03 14.1 2.3 2.5 7.8 0.3 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KDO23428.1 - 0.031 13.8 1.6 2.3 7.7 0.1 3.3 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 KDO23428.1 - 0.034 14.3 0.1 7.3 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KDO23428.1 - 0.055 12.3 0.3 0.67 8.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 KDO23428.1 - 0.056 13.8 0.0 7.1 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF111 PF01969.17 KDO23428.1 - 0.061 12.4 0.2 0.088 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 FtsK_SpoIIIE PF01580.18 KDO23428.1 - 0.067 12.5 0.4 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KDO23428.1 - 0.083 11.8 0.2 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KDO23428.1 - 0.087 12.5 0.1 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KDO23428.1 - 0.12 12.9 0.1 16 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO23428.1 - 0.13 11.5 0.4 10 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KDO23428.1 - 0.15 12.0 0.7 11 5.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain ABC_membrane PF00664.23 KDO23429.1 - 1.9e-54 185.2 38.8 1.6e-31 110.0 17.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO23429.1 - 2.5e-38 131.7 0.3 3.9e-16 59.8 0.0 3.5 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 KDO23429.1 - 3.5e-11 43.0 3.9 0.021 14.3 0.3 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO23429.1 - 7.6e-07 29.5 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KDO23429.1 - 1.6e-06 28.8 0.4 0.078 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KDO23429.1 - 1.9e-06 27.9 1.1 0.11 12.3 0.0 3.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO23429.1 - 2e-06 27.5 3.7 0.015 15.1 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO23429.1 - 9.1e-06 26.1 0.1 0.052 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO23429.1 - 1.2e-05 25.3 0.0 0.0065 16.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KDO23429.1 - 1.3e-05 25.2 0.7 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 KDO23429.1 - 0.0013 18.9 0.1 1 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KDO23429.1 - 0.0018 18.1 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KDO23429.1 - 0.0021 17.3 0.1 0.35 10.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 KDO23429.1 - 0.0022 18.1 1.2 0.23 11.5 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KDO23429.1 - 0.0033 17.2 0.1 2.2 8.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KDO23429.1 - 0.0035 17.5 2.9 0.083 13.0 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 KDO23429.1 - 0.0062 17.1 0.1 0.81 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KDO23429.1 - 0.0065 16.0 0.1 4.5 6.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 KDO23429.1 - 0.0065 16.1 0.5 0.22 11.1 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KDO23429.1 - 0.0094 15.0 0.1 1.3 8.1 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KDO23429.1 - 0.012 15.4 3.3 2.4 7.9 0.3 3.6 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KDO23429.1 - 0.02 15.3 0.0 2.5 8.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KDO23429.1 - 0.042 13.8 0.1 10 6.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KDO23429.1 - 0.042 14.2 0.0 6.5 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 KDO23429.1 - 0.044 12.9 0.2 2.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 KDO23429.1 - 0.065 12.8 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO23429.1 - 0.068 12.5 0.3 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 KDO23429.1 - 0.084 12.4 0.2 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 KDO23429.1 - 0.13 11.1 0.3 1.6 7.5 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain ATP-synt_ab PF00006.25 KDO23429.1 - 0.24 11.0 1.0 17 4.9 0.0 3.3 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 KDO23429.1 - 0.91 8.2 2.3 28 3.3 0.0 3.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PAN_4 PF14295.6 KDO23430.1 - 3.6e-07 30.0 4.1 3.6e-07 30.0 4.1 2.3 2 1 0 2 2 2 1 PAN domain ATXN-1_C PF12547.8 KDO23433.1 - 2.6 8.5 8.3 9.6 6.6 0.3 3.2 3 1 0 3 3 3 0 Capicua transcriptional repressor modulator Ank_2 PF12796.7 KDO23435.1 - 8e-39 132.1 19.0 8.1e-10 39.2 0.3 4.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO23435.1 - 4.1e-22 78.0 15.2 0.00053 20.2 0.1 8.9 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO23435.1 - 1.5e-21 76.5 12.7 2.2e-06 28.1 0.5 7.1 2 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23435.1 - 6e-11 41.6 7.3 0.85 10.4 0.0 8.6 6 1 3 9 9 9 2 Ankyrin repeat Ank PF00023.30 KDO23435.1 - 3.8e-08 33.4 5.1 3.4 8.3 0.0 8.1 3 3 3 6 6 6 1 Ankyrin repeat HA PF03457.14 KDO23435.1 - 0.003 17.9 0.0 10 6.6 0.0 5.0 2 1 1 3 3 3 1 Helicase associated domain VASt PF16016.5 KDO23436.1 - 9.3e-23 81.3 0.3 2.1e-16 60.7 0.3 2.4 2 0 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain Fascin PF06268.13 KDO23436.1 - 0.12 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Fascin domain PUB PF09409.10 KDO23437.1 - 4e-19 68.3 0.0 7.4e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 KDO23437.1 - 4.2e-14 52.0 0.0 8.9e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO23437.1 - 7.2e-07 28.9 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO23437.1 - 0.0011 19.4 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Phostensin_N PF13916.6 KDO23437.1 - 0.074 13.4 0.9 0.18 12.1 0.9 1.7 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Rad60-SLD_2 PF13881.6 KDO23437.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 KDO23437.1 - 0.19 11.7 28.9 2.4 8.2 18.6 2.6 1 1 1 2 2 2 0 STI1 domain VASt PF16016.5 KDO23438.1 - 2.5e-15 57.2 0.0 5.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Pex24p PF06398.11 KDO23438.1 - 1.4e-11 44.0 2.9 2.1e-11 43.4 2.9 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PH PF00169.29 KDO23438.1 - 2.5e-06 27.9 0.1 6.9e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO23438.1 - 0.24 11.8 2.5 2.7 8.5 2.5 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain PALP PF00291.25 KDO23440.1 - 5.5e-68 229.5 0.1 6.2e-68 229.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 KDO23440.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase EGF_Tenascin PF18720.1 KDO23441.1 - 0.0073 16.3 7.4 0.0073 16.3 7.4 6.4 6 1 0 6 6 6 1 Tenascin EGF domain EGF_2 PF07974.13 KDO23441.1 - 0.011 16.1 13.7 0.011 16.1 13.7 6.4 5 1 0 5 5 5 0 EGF-like domain Laminin_EGF PF00053.24 KDO23441.1 - 0.42 10.8 59.3 0.15 12.2 11.7 5.4 2 1 1 4 4 4 0 Laminin EGF domain Pkinase PF00069.25 KDO23442.1 - 2.2e-63 214.1 0.0 3e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23442.1 - 6.6e-29 101.0 0.0 1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO23442.1 - 3e-09 37.3 0.6 1.2e-07 32.2 0.3 2.5 2 0 0 2 2 2 1 PH domain Haspin_kinase PF12330.8 KDO23442.1 - 0.00082 18.4 0.1 0.0015 17.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO23442.1 - 0.018 14.4 0.2 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.6 KDO23442.1 - 0.16 12.4 1.2 1.2 9.6 0.3 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Pox_ser-thr_kin PF05445.11 KDO23442.1 - 0.17 10.8 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PH PF00169.29 KDO23443.1 - 1.5e-06 28.7 0.1 3.5e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 PH domain Cytochrom_C PF00034.21 KDO23444.1 - 2e-13 51.3 0.3 3.1e-13 50.7 0.3 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KDO23444.1 - 1e-06 28.9 3.8 4.9e-06 26.8 3.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KDO23444.1 - 0.0055 16.4 0.6 0.012 15.4 0.2 1.7 2 1 1 3 3 3 1 Cytochrome c-550 domain Brix PF04427.18 KDO23445.1 - 2e-27 96.6 0.9 2e-27 96.6 0.9 1.5 2 0 0 2 2 2 1 Brix domain DUF1749 PF08538.10 KDO23445.1 - 0.0022 17.2 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) FYDLN_acid PF09538.10 KDO23445.1 - 0.27 11.9 4.7 0.48 11.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RRP14 PF15459.6 KDO23445.1 - 0.42 11.2 8.4 2.1 9.0 0.0 2.9 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Ada3 PF10198.9 KDO23445.1 - 2.3 8.4 8.2 1.9 8.6 5.8 2.0 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 Lectin_legB PF00139.19 KDO23447.1 - 4.7e-06 26.3 0.0 5.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain DUF1899 PF08953.11 KDO23448.1 - 1.3e-23 82.6 0.1 2.4e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KDO23448.1 - 1.9e-18 66.1 0.0 4.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KDO23448.1 - 4.1e-15 55.9 0.7 0.0028 18.5 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23448.1 - 1.6e-07 31.5 0.2 0.00013 22.2 0.2 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO23448.1 - 0.0028 16.6 0.0 1.3 8.0 0.0 3.1 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO23448.1 - 0.0038 16.0 0.3 0.021 13.5 0.3 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DNA_Packaging_2 PF11123.8 KDO23448.1 - 0.011 16.0 0.0 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 DNA packaging protein Adeno_E3_CR2 PF02439.15 KDO23449.1 - 7.7e-05 22.4 0.3 0.00011 21.9 0.3 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 KDO23449.1 - 0.027 14.5 0.0 0.027 14.4 0.0 1.3 1 1 0 1 1 1 0 Protocadherin RIO1 PF01163.22 KDO23451.1 - 4.4e-74 248.2 0.0 4.4e-74 248.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KDO23451.1 - 0.026 13.3 0.0 0.026 13.3 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Nop53 PF07767.11 KDO23451.1 - 0.045 13.1 24.7 0.074 12.4 24.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KDO23451.1 - 0.26 9.6 26.7 0.36 9.1 26.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KDO23451.1 - 1.5 8.4 16.8 2.5 7.7 16.8 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cwf_Cwc_15 PF04889.12 KDO23451.1 - 3.4 7.3 41.5 11 5.7 41.2 1.8 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ig_mannosidase PF17753.1 KDO23452.1 - 1.9e-09 37.1 0.1 4.6e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KDO23452.1 - 1.8e-06 28.6 0.0 5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KDO23452.1 - 0.004 17.1 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain fn3 PF00041.21 KDO23454.1 - 3.9e-05 23.9 1.3 9.3e-05 22.7 1.3 1.6 1 0 0 1 1 1 1 Fibronectin type III domain TIG PF01833.24 KDO23454.1 - 0.0014 18.7 4.0 0.005 16.9 0.0 3.1 3 0 0 3 3 3 1 IPT/TIG domain Bact_lectin PF18483.1 KDO23454.1 - 0.0016 18.5 0.0 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 KDO23454.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Legume lectin domain PP2C PF00481.21 KDO23455.1 - 5.9e-45 153.9 0.0 8.7e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 KDO23455.1 - 5.8e-24 84.9 0.0 8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23455.1 - 2.2e-08 33.7 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 KDO23455.1 - 0.00071 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO23455.1 - 0.018 15.0 0.2 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) zf-C2HC_2 PF13913.6 KDO23455.1 - 0.36 10.8 2.6 0.76 9.7 1.2 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF2009 PF09418.10 KDO23456.1 - 3.4e-131 438.4 1.1 1.2e-82 278.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KDO23456.1 - 6.5e-05 23.0 6.1 6.5e-05 23.0 6.1 1.8 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 KDO23456.1 - 0.007 16.6 6.0 0.007 16.6 6.0 2.2 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 KDO23456.1 - 0.072 13.0 6.1 0.15 11.9 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.18 KDO23456.1 - 6.1 7.0 11.3 12 6.1 11.3 1.5 1 0 0 1 1 1 0 MYND finger PT PF04886.12 KDO23458.1 - 1e-11 44.1 51.4 1.4e-07 30.9 19.1 3.0 2 1 1 3 3 3 2 PT repeat DENN PF02141.21 KDO23460.1 - 1e-44 152.7 1.1 1.6e-44 152.1 1.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KDO23460.1 - 2.2e-13 50.7 0.0 7.1e-11 42.7 0.0 2.6 2 0 0 2 2 2 2 uDENN domain PDZ_6 PF17820.1 KDO23460.1 - 0.00041 20.2 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain SPA PF08616.10 KDO23460.1 - 0.083 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PDZ PF00595.24 KDO23460.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain CaiF_GrlA PF07180.11 KDO23461.1 - 0.12 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator Phage_holin_3_6 PF07332.11 KDO23462.1 - 2.4 8.2 15.7 0.14 12.2 1.7 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PH PF00169.29 KDO23463.1 - 0.017 15.6 0.2 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 PH domain CENP-Q PF13094.6 KDO23463.1 - 0.31 11.2 9.3 0.062 13.5 2.6 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SspB PF04386.13 KDO23463.1 - 3.3 7.6 7.4 10 6.0 7.4 1.8 1 1 0 1 1 1 0 Stringent starvation protein B Presenilin PF01080.17 KDO23463.1 - 3.6 6.2 3.7 5.3 5.7 3.7 1.2 1 0 0 1 1 1 0 Presenilin Senescence_reg PF04520.13 KDO23464.1 - 0.00022 22.1 0.6 0.00069 20.5 0.6 1.8 1 1 0 1 1 1 1 Senescence regulator FYVE PF01363.21 KDO23465.1 - 5.3e-05 23.3 8.8 0.00012 22.1 8.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO23465.1 - 0.15 12.3 6.1 0.32 11.2 6.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Pkinase PF00069.25 KDO23466.1 - 1.9e-45 155.3 0.0 2.3e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23466.1 - 2.8e-18 66.1 0.3 7.7e-18 64.7 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO23466.1 - 0.04 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO23467.1 - 1.4e-45 155.7 0.0 2.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23467.1 - 5.7e-39 133.9 0.0 7.9e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO23467.1 - 0.0035 16.2 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF3169 PF11368.8 KDO23467.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Mycobact_memb PF05423.13 KDO23467.1 - 0.06 13.3 0.4 0.21 11.5 0.2 1.9 2 0 0 2 2 2 0 Mycobacterium membrane protein DUF5383 PF17355.2 KDO23467.1 - 0.24 11.8 0.1 0.51 10.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Piwi PF02171.17 KDO23468.1 - 6.7e-97 324.4 0.0 9.6e-97 323.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KDO23468.1 - 7.4e-20 71.2 0.0 1.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KDO23468.1 - 9.9e-18 63.6 0.0 2e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KDO23468.1 - 3.5e-16 60.1 0.1 6.8e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KDO23468.1 - 1.7e-08 34.6 0.0 5e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KDO23468.1 - 5.9e-05 23.2 0.2 0.00061 20.0 0.0 2.6 3 0 0 3 3 3 1 Mid domain of argonaute SNARE PF05739.19 KDO23469.1 - 2e-12 46.9 0.2 2e-12 46.9 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KDO23469.1 - 2.1e-07 30.8 9.9 0.00069 19.4 0.4 2.5 3 0 0 3 3 3 2 Syntaxin V-ATPase_G_2 PF16999.5 KDO23469.1 - 0.0045 17.4 2.1 0.0045 17.4 2.1 2.4 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit MCPsignal PF00015.21 KDO23469.1 - 0.025 14.4 0.6 0.025 14.4 0.6 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GTA_holin_3TM PF11351.8 KDO23469.1 - 0.091 13.3 0.2 0.091 13.3 0.2 2.7 1 1 3 4 4 4 0 Holin of 3TMs, for gene-transfer release OmpH PF03938.14 KDO23469.1 - 6.5 7.1 12.8 17 5.8 12.6 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FR47 PF08445.10 KDO23470.1 - 0.00022 21.2 0.0 0.0018 18.2 0.0 2.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KDO23470.1 - 0.003 18.2 0.0 0.0054 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TGT PF01702.18 KDO23471.1 - 4.6e-77 259.5 0.0 5.5e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase SHE3 PF17078.5 KDO23472.1 - 0.00094 19.0 19.8 0.00094 19.0 19.8 2.3 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 Bcr-Abl_Oligo PF09036.10 KDO23472.1 - 0.086 12.9 12.8 0.42 10.6 2.0 3.4 2 2 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain YabA PF06156.13 KDO23472.1 - 0.7 10.6 27.7 0.3 11.7 1.6 4.3 2 2 1 3 3 3 0 Initiation control protein YabA MAD PF05557.13 KDO23472.1 - 4.2 5.6 48.8 0.17 10.3 19.3 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein tRNA-synt_1 PF00133.22 KDO23473.1 - 1.1e-62 212.1 2.1 1.4e-43 149.1 4.0 6.3 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KDO23473.1 - 1.4e-44 151.8 0.0 7.8e-44 149.4 0.0 2.0 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KDO23473.1 - 3.9e-27 95.0 0.0 1.6e-20 73.2 0.0 3.9 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KDO23473.1 - 2.6e-11 43.7 0.0 5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KDO23473.1 - 0.00022 20.7 0.0 0.096 12.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 KDO23473.1 - 0.037 12.9 0.1 3.1 6.6 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 KDO23473.1 - 0.061 12.2 0.0 0.96 8.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) DNA_ligase_ZBD PF03119.16 KDO23473.1 - 0.24 11.5 4.7 0.41 10.7 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 KDO23473.1 - 1.2 9.3 3.5 3.1 8.0 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain MFS_1 PF07690.16 KDO23474.1 - 1e-30 106.9 48.4 5e-20 71.7 25.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily FYVE PF01363.21 KDO23475.1 - 8.8e-07 29.0 7.7 2.3e-06 27.7 7.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger Perm-CXXC PF15629.6 KDO23475.1 - 0.61 10.4 3.4 1.5 9.2 3.4 1.6 1 0 0 1 1 1 0 Permuted single zf-CXXC unit DZR PF12773.7 KDO23475.1 - 1.3 9.1 6.7 49 4.0 0.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon AAA_16 PF13191.6 KDO23476.1 - 3.6e-05 24.2 1.0 0.00062 20.2 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KDO23476.1 - 0.003 17.5 0.0 0.015 15.2 0.0 2.2 1 1 0 1 1 1 1 NACHT domain KTI12 PF08433.10 KDO23476.1 - 0.05 13.0 0.8 0.53 9.7 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 KDO23476.1 - 2.5 8.5 0.0 2.5 8.5 0.0 3.9 2 1 1 3 3 3 0 AAA domain Neur_chan_memb PF02932.16 KDO23477.1 - 0.21 11.6 6.2 0.33 11.0 6.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4514 PF14986.6 KDO23478.1 - 0.12 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) zf-RING_2 PF13639.6 KDO23482.1 - 1.6e-16 60.3 28.9 1.2e-09 38.4 5.8 3.3 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 KDO23482.1 - 6.6e-13 48.5 15.2 1.2e-07 31.6 1.5 3.7 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_11 PF17123.5 KDO23482.1 - 1.1e-12 47.4 13.0 4.2e-06 26.4 3.5 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 KDO23482.1 - 1.2e-12 47.6 23.6 4.9e-08 32.8 4.0 3.5 3 0 0 3 3 3 2 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO23482.1 - 3e-09 36.8 5.7 8.8e-05 22.5 0.7 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO23482.1 - 1.2e-08 34.7 23.3 8.8e-05 22.3 3.5 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO23482.1 - 3e-06 27.4 22.1 1.3e-05 25.4 3.0 3.6 3 2 0 3 3 2 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO23482.1 - 6.5e-06 25.9 25.6 0.00012 21.9 3.6 3.0 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO23482.1 - 2.4e-05 24.1 27.8 0.00065 19.5 5.2 3.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KDO23482.1 - 2.7e-05 23.9 18.1 0.0016 18.2 1.5 3.7 3 1 0 3 3 3 2 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KDO23482.1 - 0.00016 21.2 21.2 0.0052 16.4 4.3 3.4 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO23482.1 - 0.0035 17.2 28.5 0.035 14.0 5.2 4.2 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 IQ PF00612.27 KDO23482.1 - 0.0086 15.8 1.3 0.0086 15.8 1.3 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif zf-HC5HC2H PF13771.6 KDO23482.1 - 0.067 13.4 0.1 0.067 13.4 0.1 3.0 3 0 0 3 3 3 0 PHD-like zinc-binding domain Zn-C2H2_12 PF18112.1 KDO23482.1 - 0.91 10.1 8.7 7.8 7.1 0.4 4.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 KDO23482.1 - 1.7 8.3 7.7 0.4 10.4 1.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RanBP PF00641.18 KDO23482.1 - 3.2 7.1 15.5 0.039 13.3 1.4 4.0 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others zf-C3HC4_4 PF15227.6 KDO23482.1 - 4.3 7.6 27.9 0.44 10.7 5.2 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.9 KDO23482.1 - 5.4 7.5 12.0 3.9 8.0 0.1 3.8 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 DUF5318 PF17249.2 KDO23482.1 - 6.6 6.5 7.7 6.1 6.6 0.2 3.5 2 1 0 2 2 2 0 Family of unknown function (DUF5318) zf-Di19 PF05605.12 KDO23482.1 - 9.4 6.6 17.0 6.2 7.2 0.5 4.3 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.8 KDO23482.1 - 9.8 6.4 14.1 15 5.8 2.7 3.4 2 2 0 2 2 2 0 FANCL C-terminal domain EF-hand_7 PF13499.6 KDO23483.1 - 7e-06 26.4 0.0 0.009 16.4 0.0 3.0 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO23483.1 - 0.00017 21.3 0.0 0.57 10.2 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain DUF5580 PF17743.1 KDO23483.1 - 0.013 14.1 0.0 0.31 9.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5580) TauD PF02668.16 KDO23485.1 - 6.4e-38 131.1 0.0 1.1e-37 130.3 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KDO23485.1 - 1.4e-17 64.1 0.0 2.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) HD PF01966.22 KDO23485.1 - 8.5e-06 26.0 0.6 1.7e-05 25.1 0.6 1.5 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KDO23485.1 - 0.0075 16.0 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KDO23485.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 HDOD domain CsiD PF08943.10 KDO23485.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 CsiD DnaJ PF00226.31 KDO23486.1 - 1.7e-21 76.1 0.1 3.7e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain BaffR-Tall_bind PF09256.10 KDO23486.1 - 0.22 11.3 0.2 0.45 10.3 0.2 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding SR-25 PF10500.9 KDO23487.1 - 0.075 12.6 7.4 0.13 11.8 7.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TSC22 PF01166.18 KDO23487.1 - 0.28 11.5 4.1 4.9 7.6 0.2 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family Coilin_N PF15862.5 KDO23487.1 - 6.3 6.6 10.1 11 5.8 10.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus FYVE PF01363.21 KDO23488.1 - 5.1e-06 26.5 10.2 5.1e-06 26.5 10.2 2.5 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO23488.1 - 0.0022 18.2 26.0 0.0035 17.5 8.9 2.4 2 0 0 2 2 2 2 FYVE-type zinc finger FYVE PF01363.21 KDO23489.1 - 0.00018 21.6 25.4 0.0022 18.1 9.2 2.6 2 0 0 2 2 2 2 FYVE zinc finger DUF4586 PF15239.6 KDO23490.1 - 0.0068 16.6 0.3 0.12 12.6 0.2 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4586) SDF PF00375.18 KDO23491.1 - 7.5e-52 176.7 13.4 4.5e-51 174.1 13.4 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2306 PF10067.9 KDO23492.1 - 9.6e-14 51.8 9.6 9.6e-14 51.8 9.6 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) FAD_binding_6 PF00970.24 KDO23492.1 - 6.3e-09 36.1 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KDO23492.1 - 0.00025 21.2 0.2 0.02 15.0 0.1 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF420 PF04238.12 KDO23492.1 - 0.0063 16.8 11.4 0.041 14.2 0.4 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF420) NAD_binding_1 PF00175.21 KDO23492.1 - 0.022 15.4 0.1 0.9 10.2 0.1 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain SDF PF00375.18 KDO23493.1 - 1.3e-49 169.3 24.8 1.5e-48 165.8 24.8 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO23494.1 - 1.4e-50 172.4 34.0 4.4e-50 170.8 34.0 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family GRASP55_65 PF04495.14 KDO23495.1 - 5.7e-56 188.7 0.0 4e-41 140.6 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KDO23495.1 - 0.0021 18.4 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Rib_recp_KP_reg PF05104.12 KDO23495.1 - 1 10.4 9.3 1.8 9.6 9.3 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Sel1 PF08238.12 KDO23496.1 - 4.2e-24 84.4 17.9 4.5e-05 24.0 0.2 7.5 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.6 KDO23496.1 - 0.19 12.4 19.5 0.19 12.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO23496.1 - 1.3 9.6 9.3 22 5.7 0.4 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO23496.1 - 1.3 9.0 29.3 0.18 11.7 3.6 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO23496.1 - 3.1 8.5 29.4 0.2 12.4 6.0 5.6 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO23496.1 - 4.8 6.9 17.8 0.97 9.2 0.7 4.7 3 1 1 4 4 4 0 TPR repeat SDF PF00375.18 KDO23497.1 - 1.8e-76 257.7 26.9 2.1e-60 204.8 18.2 2.0 2 0 0 2 2 2 2 Sodium:dicarboxylate symporter family Gly-zipper_Omp PF13488.6 KDO23497.1 - 0.0037 17.2 1.0 0.018 15.0 0.3 2.4 2 0 0 2 2 2 1 Glycine zipper PglL_A PF15864.5 KDO23497.1 - 0.12 12.2 0.7 0.64 9.8 0.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase WW PF00397.26 KDO23498.1 - 0.00012 22.1 1.7 0.018 15.1 0.2 2.6 2 0 0 2 2 2 2 WW domain Ank_3 PF13606.6 KDO23499.1 - 4.9e-11 41.9 0.2 0.00067 19.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO23499.1 - 4.9e-10 39.9 0.1 1.1e-09 38.7 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23499.1 - 6.2e-08 33.0 0.2 0.00022 21.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO23499.1 - 2.3e-07 31.0 2.8 0.00013 22.2 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO23499.1 - 7.2e-05 23.0 1.2 0.0044 17.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO23500.1 - 2.2e-18 66.4 0.4 5.4e-11 42.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23500.1 - 6.5e-17 61.9 0.0 2.6e-14 53.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO23500.1 - 2e-16 58.4 0.8 4.4e-06 26.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO23500.1 - 1.5e-13 50.7 0.9 2.1e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO23500.1 - 1.5e-11 44.2 0.5 0.00025 21.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat FYVE PF01363.21 KDO23502.1 - 0.00013 22.0 12.6 0.00028 20.9 12.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO23502.1 - 2 8.6 11.0 0.41 10.9 6.6 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger WD40 PF00400.32 KDO23503.1 - 2.3e-56 186.5 7.2 1e-08 35.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23503.1 - 3e-25 88.3 0.1 0.0011 19.2 0.1 6.1 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO23503.1 - 2.4e-09 37.4 0.0 0.00025 21.0 0.0 3.5 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KDO23503.1 - 5.2e-09 35.3 6.4 0.053 12.2 0.1 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO23503.1 - 3.9e-08 32.6 0.1 0.14 11.1 0.0 4.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KDO23503.1 - 4.2e-08 32.9 0.0 0.0046 16.3 0.0 3.8 2 1 2 4 4 4 3 WD40-like domain Cytochrom_D1 PF02239.16 KDO23503.1 - 0.00026 19.7 0.1 0.15 10.5 0.0 2.6 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.6 KDO23503.1 - 0.00037 19.9 0.4 2.9 7.1 0.0 4.0 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Itfg2 PF15907.5 KDO23503.1 - 0.0091 15.1 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 PHTB1_N PF14727.6 KDO23503.1 - 0.017 14.5 0.0 0.068 12.5 0.0 1.9 2 1 0 2 2 2 0 PTHB1 N-terminus CbiG_N PF11760.8 KDO23503.1 - 0.078 13.0 0.1 4.6 7.3 0.1 2.7 3 0 0 3 3 3 0 Cobalamin synthesis G N-terminal RNA_pol_Rpc34 PF05158.12 KDO23504.1 - 6.9e-68 229.5 1.5 4.1e-49 167.8 0.4 2.1 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit E1_UFD PF09358.10 KDO23504.1 - 0.00083 20.0 0.4 0.31 11.8 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin fold domain RPA_C PF08784.11 KDO23504.1 - 0.0091 16.6 0.1 0.024 15.3 0.1 1.7 1 0 0 1 1 1 1 Replication protein A C terminal TrmB PF01978.19 KDO23504.1 - 0.012 15.4 0.1 0.033 14.1 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KDO23504.1 - 0.016 15.4 0.7 0.036 14.2 0.1 1.9 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_27 PF13463.6 KDO23504.1 - 0.031 14.8 0.1 0.066 13.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.20 KDO23504.1 - 0.084 13.2 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator HMD PF03201.16 KDO23504.1 - 0.099 12.9 0.3 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TFIIE_alpha PF02002.17 KDO23504.1 - 0.11 12.4 0.4 0.72 9.7 0.2 2.3 2 0 0 2 2 2 0 TFIIE alpha subunit WD40 PF00400.32 KDO23505.1 - 2.4e-40 135.8 21.4 1.5e-06 28.8 0.1 12.2 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 KDO23505.1 - 2.7e-23 82.3 1.0 5.1e-23 81.4 1.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KDO23505.1 - 2.2e-22 79.1 0.0 0.0045 17.3 0.0 8.7 2 2 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO23505.1 - 5.1e-06 25.7 1.2 0.94 8.4 0.1 5.9 4 3 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO23505.1 - 9.7e-05 21.2 2.9 0.053 12.2 0.0 3.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KDO23505.1 - 0.00018 20.2 0.3 1.6 7.1 0.1 3.4 3 0 0 3 3 3 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KDO23505.1 - 0.0093 15.6 0.4 4 7.2 0.0 4.2 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature WD40_like PF17005.5 KDO23505.1 - 0.011 15.1 0.0 0.24 10.7 0.0 2.8 2 1 1 4 4 4 0 WD40-like domain PD40 PF07676.12 KDO23505.1 - 0.011 15.6 0.7 91 3.2 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KDO23505.1 - 0.018 14.2 0.0 0.53 9.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Exo_endo_phos PF03372.23 KDO23506.1 - 5.7e-14 52.2 1.9 9.1e-14 51.5 1.9 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Laminin_B PF00052.18 KDO23507.1 - 9e-16 58.0 0.0 2.9e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 Laminin B (Domain IV) Rep_1B PF17873.1 KDO23507.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Replicase polyprotein 1ab DAGAT PF03982.13 KDO23508.1 - 5e-56 189.8 0.0 6.5e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ank_2 PF12796.7 KDO23509.1 - 2.4e-80 265.2 30.7 7e-15 55.4 0.2 7.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO23509.1 - 1.8e-61 203.4 31.9 2.4e-10 40.4 0.1 13.5 2 2 12 14 14 14 14 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO23509.1 - 3e-60 199.8 15.0 1.2e-08 35.3 0.0 10.3 5 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23509.1 - 3.8e-56 180.4 22.1 0.00023 21.4 0.0 15.1 15 0 0 15 15 15 14 Ankyrin repeat Ank PF00023.30 KDO23509.1 - 3e-52 172.9 38.1 1.6e-05 25.2 0.0 14.7 14 1 1 15 15 15 13 Ankyrin repeat DAGAT PF03982.13 KDO23510.1 - 8.1e-54 182.5 0.1 9.4e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase KH_1 PF00013.29 KDO23511.1 - 6.3e-09 35.5 0.0 0.0005 19.8 0.0 2.4 2 0 0 2 2 2 2 KH domain SLS PF14611.6 KDO23511.1 - 0.019 14.8 0.2 0.35 10.7 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 KDO23512.1 - 3.4e-06 26.8 0.0 0.00057 19.7 0.0 3.2 3 0 0 3 3 3 1 KH domain SLS PF14611.6 KDO23512.1 - 0.0034 17.2 0.5 0.013 15.3 0.4 2.1 1 1 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Mucin PF01456.17 KDO23512.1 - 0.037 14.0 65.9 0.21 11.6 44.5 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Dynein_light PF01221.18 KDO23514.1 - 1.7e-22 79.5 0.1 2e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Lipocalin_5 PF13924.6 KDO23514.1 - 0.019 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipocalin-like domain fn3 PF00041.21 KDO23515.1 - 3.1e-08 33.9 0.1 6.1e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ank_5 PF13857.6 KDO23515.1 - 2.3e-06 27.8 0.0 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23515.1 - 0.00032 20.9 0.1 0.0016 18.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KDO23515.1 - 0.00033 21.1 0.1 0.0028 18.2 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23515.1 - 0.012 16.2 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KDO23515.1 - 0.021 15.3 0.1 0.28 11.7 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Peptidase_C1 PF00112.23 KDO23517.1 - 1.4e-46 159.3 2.6 2.5e-46 158.5 2.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Ricin_B_lectin PF00652.22 KDO23517.1 - 4.4e-27 94.8 14.5 1e-14 54.9 1.4 3.0 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO23517.1 - 2.2e-10 41.1 11.0 4.1e-06 27.4 1.2 4.6 1 1 3 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO23517.1 - 1.6e-05 24.6 0.1 0.086 12.4 0.0 2.6 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain PNP_UDP_1 PF01048.20 KDO23518.1 - 3e-23 82.3 0.3 3.4e-23 82.1 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 KDO23519.1 - 4.8e-22 78.4 0.9 5.7e-22 78.1 0.9 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily CwsA PF10814.8 KDO23519.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA TPR_11 PF13414.6 KDO23519.1 - 0.24 11.1 1.4 9 6.1 0.1 2.7 3 0 0 3 3 3 0 TPR repeat Na_H_Exchanger PF00999.21 KDO23520.1 - 5.4e-38 130.8 41.9 6.9e-38 130.4 41.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Lectin_N PF03954.14 KDO23520.1 - 0.036 13.8 0.9 0.14 11.9 0.9 2.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain RRM_1 PF00076.22 KDO23521.1 - 1.4e-06 28.1 0.0 0.00019 21.2 0.0 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO23521.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rep_Org_C PF06926.11 KDO23521.1 - 0.11 12.8 0.2 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus 2OG-FeII_Oxy_3 PF13640.6 KDO23522.1 - 6.4e-14 52.6 0.1 5.3e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SIN1_PH PF16979.5 KDO23522.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SNF2_N PF00176.23 KDO23523.1 - 9.1e-45 152.9 0.1 1.6e-44 152.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO23523.1 - 7.3e-15 55.3 0.0 2.7e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KDO23523.1 - 1.7e-06 27.4 0.0 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 KDO23523.1 - 0.074 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Ras PF00071.22 KDO23524.1 - 2e-51 173.8 0.1 2.4e-51 173.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23524.1 - 1.6e-33 115.5 0.0 2.3e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23524.1 - 1.3e-13 50.7 0.3 1.6e-13 50.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO23524.1 - 9.2e-07 28.4 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KDO23524.1 - 0.00059 19.4 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO23524.1 - 0.00062 19.3 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO23524.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 KDO23524.1 - 0.0069 16.4 0.2 0.035 14.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain P_C PF06640.11 KDO23524.1 - 0.021 15.0 3.4 0.032 14.4 3.4 1.3 1 0 0 1 1 1 0 P protein C-terminus RST PF12174.8 KDO23524.1 - 0.2 11.6 0.6 3 7.8 0.0 2.2 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain WD40 PF00400.32 KDO23525.1 - 7.7e-06 26.6 10.0 0.4 11.6 0.3 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23525.1 - 0.066 13.5 0.0 19 5.6 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PhyH PF05721.13 KDO23526.1 - 7.8e-08 32.8 0.2 8.1e-07 29.5 0.2 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-met2 PF12907.7 KDO23527.1 - 0.001 19.1 0.2 0.0026 17.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding VKOR PF07884.14 KDO23528.1 - 0.24 11.6 8.5 0.55 10.4 3.0 2.6 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DUF2070 PF09843.9 KDO23528.1 - 3.8 5.7 8.0 0.59 8.4 4.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Marek_A PF02124.15 KDO23529.1 - 0.061 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF3135 PF11333.8 KDO23529.1 - 0.079 13.2 1.3 11 6.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) Beta-lactamase PF00144.24 KDO23530.1 - 5e-51 173.9 2.4 6.9e-51 173.4 2.4 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO23530.1 - 0.0015 18.2 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase enzyme family PARP PF00644.20 KDO23531.1 - 3.3e-05 23.6 0.5 0.003 17.2 0.1 2.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Pkinase PF00069.25 KDO23532.1 - 1.2e-70 237.9 0.0 1.6e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23532.1 - 4e-35 121.4 0.0 5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KDO23532.1 - 7.1e-15 55.0 0.0 2e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 KDO23532.1 - 4.4e-08 32.8 0.0 7.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KDO23532.1 - 4.9e-06 27.1 4.8 1.2e-05 25.9 4.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KDO23532.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KDO23532.1 - 0.0033 17.1 0.1 0.18 11.4 0.1 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Complex1_LYR_2 PF13233.6 KDO23533.1 - 8.8e-16 58.4 1.1 1.3e-15 57.9 1.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KDO23533.1 - 9.8e-08 31.9 0.4 1.5e-07 31.3 0.1 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4455 PF14643.6 KDO23533.1 - 0.018 13.7 0.6 0.017 13.8 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) HAUS5 PF14817.6 KDO23534.1 - 7e-09 35.0 36.2 4.6e-05 22.4 10.0 3.1 1 1 2 3 3 3 3 HAUS augmin-like complex subunit 5 Neuro_bHLH PF12533.8 KDO23534.1 - 0.1 13.8 1.3 0.39 11.9 1.3 2.0 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor Aminotran_1_2 PF00155.21 KDO23535.1 - 1.8e-39 136.0 0.0 2.5e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_psq PF05225.16 KDO23535.1 - 6e-08 32.3 0.1 1.2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Tubulin PF00091.25 KDO23536.1 - 2.7e-69 233.3 0.1 7.7e-69 231.8 0.0 1.8 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO23536.1 - 3.9e-49 166.0 0.1 8.1e-49 165.0 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KDO23536.1 - 7.5e-06 26.2 0.0 1.8e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KDO23536.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DDE_1 PF03184.19 KDO23538.1 - 0.0037 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_35 PF14516.6 KDO23538.1 - 0.14 11.0 0.4 3.9 6.2 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain ATG16 PF08614.11 KDO23539.1 - 6.7e-06 26.5 48.9 0.0038 17.5 18.3 2.9 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KDO23539.1 - 0.0015 18.0 21.8 0.046 13.1 2.6 2.6 1 1 1 2 2 2 2 FAM76 protein DUF1664 PF07889.12 KDO23539.1 - 0.17 11.9 20.0 0.14 12.2 1.3 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KDO23539.1 - 0.19 12.0 0.1 0.19 12.0 0.1 4.0 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KDO23539.1 - 0.24 11.8 37.4 0.5 10.8 12.5 3.0 1 1 2 3 3 3 0 Fez1 Golgin_A5 PF09787.9 KDO23539.1 - 0.72 9.3 37.8 1.1 8.7 7.9 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Rab5-bind PF09311.11 KDO23539.1 - 2 7.7 32.0 7 5.9 4.3 2.6 1 1 1 2 2 2 0 Rabaptin-like protein CtIP_N PF10482.9 KDO23539.1 - 2.7 8.1 22.7 1.3 9.0 0.6 4.3 1 1 4 5 5 5 0 Tumour-suppressor protein CtIP N-terminal domain PglZ PF08665.12 KDO23539.1 - 2.7 8.0 14.3 11 6.1 1.5 3.1 2 1 1 3 3 3 0 PglZ domain Exonuc_VII_L PF02601.15 KDO23539.1 - 4.3 6.8 32.8 9 5.8 19.6 2.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit Kinesin_assoc PF16183.5 KDO23539.1 - 4.4 7.4 8.6 63 3.6 8.5 2.6 1 1 0 1 1 1 0 Kinesin-associated DUF3584 PF12128.8 KDO23539.1 - 9.4 3.6 41.9 3.7 4.9 19.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.11 KDO23539.1 - 9.7 4.9 44.9 1.8 7.3 11.5 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.10 KDO23539.1 - 9.9 6.3 17.2 3.7 7.7 4.0 3.2 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myb_DNA-binding PF00249.31 KDO23540.1 - 4.7e-11 42.7 9.0 7.9e-09 35.6 1.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO23540.1 - 3.6e-10 39.9 7.1 8.2e-07 29.2 0.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KDO23540.1 - 0.017 15.2 2.1 0.031 14.3 2.1 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KDO23540.1 - 0.44 10.9 7.0 0.4 11.1 3.6 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO23541.1 - 4.1e-11 42.9 8.4 3.5e-07 30.3 1.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO23541.1 - 3.4e-09 36.8 7.0 1.9e-05 24.8 0.9 2.8 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO23541.1 - 0.45 10.9 9.9 0.086 13.2 4.8 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 KDO23541.1 - 0.52 10.4 3.0 1 9.5 3.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ZZ PF00569.17 KDO23542.1 - 5.1e-09 35.8 4.5 5.1e-09 35.8 4.5 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type cNMP_binding PF00027.29 KDO23543.1 - 1.1e-21 76.7 0.0 8.7e-12 45.0 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain PX PF00787.24 KDO23544.1 - 4.1e-07 30.0 0.0 7.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO23545.1 - 9.9e-06 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO23546.1 - 9.7e-07 28.8 0.1 1.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 PX domain PDZ_6 PF17820.1 KDO23547.1 - 4.8e-05 23.1 0.7 0.00014 21.6 0.3 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KDO23547.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO23547.1 - 0.0056 17.0 0.0 0.0093 16.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain V-SNARE_C PF12352.8 KDO23549.1 - 6.7e-05 23.1 3.1 8.9e-05 22.7 3.1 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Pcc1 PF09341.10 KDO23551.1 - 4.9e-10 39.4 0.1 7.8e-10 38.8 0.1 1.3 1 1 0 1 1 1 1 Transcription factor Pcc1 AAA PF00004.29 KDO23552.1 - 1.3e-12 48.3 0.0 1.2e-11 45.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO23552.1 - 1.6e-10 41.6 0.0 2.4e-08 34.6 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO23552.1 - 4.3e-10 40.0 0.0 1.2e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KDO23552.1 - 3.7e-06 27.0 0.1 9.4e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KDO23552.1 - 0.0016 18.8 0.0 0.0096 16.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KDO23552.1 - 0.021 14.8 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KDO23552.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.12 KDO23552.1 - 0.074 13.0 0.8 0.28 11.1 0.1 2.4 3 1 0 3 3 3 0 NACHT domain DUF815 PF05673.13 KDO23552.1 - 0.083 12.0 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Histone PF00125.24 KDO23553.1 - 7.3e-16 58.7 3.4 8.1e-16 58.6 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Glutaredoxin PF00462.24 KDO23555.1 - 1.3e-07 31.8 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KDO23555.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) PCMT PF01135.19 KDO23555.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cellulase PF00150.18 KDO23556.1 - 4.3e-23 82.1 2.7 5.1e-23 81.9 2.7 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 KDO23556.1 - 0.033 14.2 0.1 0.11 12.5 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) AP_endonuc_2 PF01261.24 KDO23556.1 - 0.11 12.0 0.0 0.54 9.7 0.0 2.0 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Trypsin PF00089.26 KDO23557.1 - 9.9e-46 156.3 1.4 1.2e-45 156.0 1.4 1.1 1 0 0 1 1 1 1 Trypsin Glutaredoxin PF00462.24 KDO23557.1 - 1.1e-06 28.8 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KDO23557.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Histone PF00125.24 KDO23558.1 - 5e-20 72.2 0.2 6.2e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KDO23558.1 - 0.00021 21.7 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KDO23558.1 - 0.0014 18.9 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KDO23558.1 - 0.0021 18.1 0.1 0.0025 17.9 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein RCC1 PF00415.18 KDO23559.1 - 6.5e-52 174.0 31.2 6.7e-14 52.3 0.2 8.5 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO23559.1 - 8.4e-28 95.6 39.0 7.8e-08 31.9 0.9 7.3 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KDO23559.1 - 1.9e-23 82.8 0.0 7e-11 42.3 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain SUKH-3 PF14433.6 KDO23559.1 - 0.15 12.5 0.2 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 SUKH-3 immunity protein MPLKIP PF15502.6 KDO23561.1 - 0.043 14.0 0.4 0.14 12.4 0.4 1.9 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein ECM1 PF05782.11 KDO23561.1 - 0.4 9.6 3.4 0.53 9.2 3.4 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) PT PF04886.12 KDO23562.1 - 7.2e-11 41.4 77.7 0.00045 19.7 23.4 4.4 3 1 0 3 3 3 3 PT repeat Trypan_PARP PF05887.11 KDO23562.1 - 0.15 12.0 20.4 0.81 9.7 4.1 3.2 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Rav1p_C PF12234.8 KDO23563.1 - 4.5e-33 114.6 7.9 8.6e-32 110.3 7.9 2.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 KDO23563.1 - 0.014 15.7 0.0 2.2 8.6 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF5052 PF16475.5 KDO23563.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) WD40 PF00400.32 KDO23563.1 - 0.34 11.8 12.4 0.26 12.2 0.4 6.1 6 0 0 6 6 6 0 WD domain, G-beta repeat Nipped-B_C PF12830.7 KDO23564.1 - 2.4e-24 86.3 0.1 2.4e-24 86.3 0.1 2.9 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KDO23564.1 - 4.4e-07 30.1 8.7 9.4e-07 29.0 0.3 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KDO23564.1 - 4.1e-05 23.5 8.6 0.37 11.2 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KDO23564.1 - 0.0074 16.7 8.6 1.4 9.4 0.0 5.3 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KDO23564.1 - 0.0095 16.4 3.1 7.8 7.1 0.1 5.2 5 0 0 5 5 5 1 HEAT-like repeat Sec7 PF01369.20 KDO23564.1 - 0.022 14.4 0.1 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 Sec7 domain Cnd1 PF12717.7 KDO23564.1 - 0.035 14.2 11.8 13 5.8 0.1 5.5 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Rhodanese PF00581.20 KDO23567.1 - 1.5e-10 41.5 0.0 2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_5 PF00266.19 KDO23568.1 - 1e-20 74.1 0.0 9.2e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KDO23568.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II PTCB-BRCT PF12738.7 KDO23569.1 - 1.5e-14 53.6 0.2 7.2e-12 45.1 0.0 3.0 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KDO23569.1 - 4.6e-12 46.2 0.0 4.6e-06 26.9 0.0 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KDO23569.1 - 1.1e-09 38.1 0.3 1.1e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KDO23569.1 - 4.6e-08 33.4 0.0 0.004 17.5 0.0 3.2 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KDO23569.1 - 0.058 13.7 0.4 32 4.9 0.1 3.5 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain Endomucin PF07010.12 KDO23569.1 - 1.7 8.6 17.6 2.4 8.1 17.6 1.1 1 0 0 1 1 1 0 Endomucin SMYLE_N PF18615.1 KDO23569.1 - 1.8 8.0 6.4 2.9 7.3 6.4 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PTCB-BRCT PF12738.7 KDO23570.1 - 6.7e-12 45.2 0.0 2.5e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 KDO23570.1 - 3e-11 43.6 0.0 8.9e-08 32.4 0.0 3.0 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO23570.1 - 4.6e-08 33.3 0.0 0.001 19.4 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KDO23570.1 - 0.15 12.3 0.3 16 5.9 0.0 3.6 5 0 0 5 5 5 0 DNA ligase 3 BRCT domain S_2TMBeta PF18153.1 KDO23571.1 - 0.3 10.9 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain Hexapep PF00132.24 KDO23573.1 - 3.1e-12 45.7 4.2 1.7e-09 37.0 2.9 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KDO23573.1 - 3.7e-06 26.6 2.4 3.8e-05 23.3 1.9 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase ZapB PF06005.12 KDO23574.1 - 0.023 15.1 2.2 0.032 14.7 2.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.12 KDO23574.1 - 0.036 14.5 3.1 0.042 14.2 3.1 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 KDO23574.1 - 0.12 13.1 0.5 0.14 12.8 0.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CPBP PF02517.16 KDO23576.1 - 8.5e-12 45.3 5.5 8.5e-12 45.3 5.5 2.5 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Type_ISP_C PF18135.1 KDO23576.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain Globin PF00042.22 KDO23577.1 - 2.4e-05 24.9 0.0 0.0001 22.8 0.0 2.0 1 1 0 1 1 1 1 Globin DUF4638 PF15472.6 KDO23579.1 - 0.0079 16.0 0.1 0.0087 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4638) WT1 PF02165.15 KDO23579.1 - 0.015 14.5 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Wilm's tumour protein CoA_trans PF01144.23 KDO23580.1 - 5.1e-115 382.3 1.2 2.4e-74 249.4 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase TPR_12 PF13424.6 KDO23581.1 - 3.4e-37 126.6 15.4 1.1e-14 54.4 5.5 5.8 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO23581.1 - 6.4e-30 102.2 32.7 1e-07 31.6 3.3 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat SAM_1 PF00536.30 KDO23581.1 - 5e-13 49.3 0.0 1.1e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO23581.1 - 1.5e-12 47.5 0.0 3.5e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CHAT PF12770.7 KDO23581.1 - 2.5e-11 43.5 0.4 2.5e-11 43.5 0.4 1.7 2 0 0 2 2 2 1 CHAT domain TPR_1 PF00515.28 KDO23581.1 - 3.1e-06 26.7 15.8 0.00029 20.5 1.6 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO23581.1 - 0.00057 19.7 16.1 0.16 12.1 0.6 6.0 7 0 0 7 7 5 2 Tetratricopeptide repeat KH_1 PF00013.29 KDO23581.1 - 0.00063 19.5 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 KH domain AAA_25 PF13481.6 KDO23581.1 - 0.00067 19.3 0.0 0.0025 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO23581.1 - 0.00078 19.9 3.7 0.0029 18.0 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.6 KDO23581.1 - 0.00087 19.3 12.4 0.082 13.2 0.5 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO23581.1 - 0.001 18.5 0.6 0.001 18.5 0.6 2.3 2 0 0 2 2 2 1 MalT-like TPR region AAA_22 PF13401.6 KDO23581.1 - 0.001 19.3 0.0 0.0039 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 KDO23581.1 - 0.0018 18.7 0.6 0.062 13.8 1.7 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23581.1 - 0.0023 18.6 2.2 6 8.0 0.1 4.5 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23581.1 - 0.0046 17.0 1.5 0.0046 17.0 1.5 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO23581.1 - 0.0054 17.0 6.7 2.2 8.9 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO23581.1 - 0.01 16.5 5.3 0.8 10.4 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NACHT PF05729.12 KDO23581.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SHNi-TPR PF10516.9 KDO23581.1 - 0.025 14.1 3.6 0.41 10.1 0.1 3.9 4 0 0 4 4 4 0 SHNi-TPR NB-ARC PF00931.22 KDO23581.1 - 0.041 13.1 0.0 0.11 11.6 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KDO23581.1 - 0.048 13.6 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Peptidase_C14 PF00656.22 KDO23581.1 - 0.095 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Caspase domain KH_2 PF07650.17 KDO23581.1 - 0.12 12.2 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 KH domain ANAPC3 PF12895.7 KDO23581.1 - 0.46 10.7 2.7 6.2 7.1 2.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_11 PF17123.5 KDO23582.1 - 0.54 10.0 4.4 2.9 7.7 4.4 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 KDO23582.1 - 2.8 8.3 10.8 0.22 11.9 5.9 1.7 2 0 0 2 2 2 0 Ring finger domain RabGAP-TBC PF00566.18 KDO23583.1 - 9.8e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIT1_PvcA PF05141.12 KDO23584.1 - 2.6e-73 246.9 0.0 3.6e-72 243.2 0.0 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.12 KDO23585.1 - 9.8e-63 212.2 0.0 2e-35 122.6 0.0 2.2 1 1 1 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KDO23585.1 - 3.7e-28 99.1 0.3 6.9e-28 98.2 0.3 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ank_4 PF13637.6 KDO23586.1 - 1.7e-07 31.6 0.1 0.0097 16.5 0.0 4.0 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23586.1 - 0.00014 22.4 0.1 0.0068 17.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO23586.1 - 0.00077 19.7 1.5 27 5.8 0.0 5.3 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 KDO23586.1 - 0.0045 17.3 0.9 8.9 6.8 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) GMP_PDE_delta PF05351.11 KDO23586.1 - 0.02 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 GMP-PDE, delta subunit Hexapep PF00132.24 KDO23586.1 - 0.02 14.6 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Ank PF00023.30 KDO23586.1 - 0.049 14.1 3.3 2.9 8.5 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 KDO23587.1 - 1.2e-13 51.4 0.2 1.9e-05 25.2 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23587.1 - 7.3e-11 42.4 0.4 3.3e-06 27.5 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23587.1 - 8.8e-10 38.0 3.3 1.5 9.7 0.1 6.6 5 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KDO23587.1 - 2.5e-06 27.6 2.2 1.5 9.2 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO23587.1 - 0.011 16.1 6.8 1.5 9.4 0.1 4.5 5 0 0 5 5 5 0 Ankyrin repeat HEAT_2 PF13646.6 KDO23589.1 - 0.0026 18.1 5.8 4.2 7.8 0.0 5.1 4 2 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KDO23589.1 - 0.01 16.3 13.7 1.1 9.9 0.0 6.3 6 2 1 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KDO23589.1 - 0.063 13.9 0.2 31 5.2 0.0 3.7 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region LSM PF01423.22 KDO23590.1 - 6.3e-21 73.8 0.2 7.9e-21 73.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain Peptidase_M16_M PF16187.5 KDO23590.1 - 0.026 13.8 0.1 0.03 13.6 0.1 1.0 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 DNA_pol3_tau_5 PF12170.8 KDO23590.1 - 0.041 13.9 0.1 0.048 13.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Fib_alpha PF08702.10 KDO23590.1 - 0.051 13.8 0.1 0.064 13.4 0.1 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KDO23590.1 - 0.055 14.0 0.3 0.077 13.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Tup_N PF08581.10 KDO23590.1 - 0.34 11.2 3.9 0.53 10.6 3.9 1.3 1 1 0 1 1 1 0 Tup N-terminal DUF1054 PF06335.12 KDO23591.1 - 0.17 11.8 1.8 1.3 8.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) DUF4078 PF13300.6 KDO23591.1 - 0.31 11.4 8.6 0.6 10.5 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Vac7 PF12751.7 KDO23591.1 - 2.3 7.5 12.7 3.7 6.9 2.8 2.0 1 1 1 2 2 2 0 Vacuolar segregation subunit 7 DUF3689 PF12463.8 KDO23592.1 - 2.3e-90 303.1 2.4 1.1e-89 300.8 2.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) Ribosomal_60s PF00428.19 KDO23594.1 - 2.2e-12 47.4 12.4 3.6e-12 46.7 12.4 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Acyl_transf_2 PF02273.15 KDO23595.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Acyl transferase Nrap PF03813.14 KDO23597.1 - 1.3e-34 119.5 0.0 2.2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KDO23597.1 - 1.1e-33 116.6 0.0 2.1e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 KDO23597.1 - 8.9e-31 106.9 0.0 1.7e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KDO23597.1 - 1.3e-28 99.8 8.8 1.1e-27 96.8 1.7 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KDO23597.1 - 2.2e-26 92.5 6.4 2.4e-24 85.8 4.1 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 KDO23597.1 - 1.1e-15 58.1 0.0 1.9e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 Ank_2 PF12796.7 KDO23598.1 - 2.3e-08 34.5 0.1 0.0077 16.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23598.1 - 5.7e-07 30.0 1.1 0.17 12.5 0.0 3.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23598.1 - 4.5e-06 26.8 0.4 0.008 16.5 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23598.1 - 1.3e-05 25.2 0.3 11 7.0 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat BKACE PF05853.12 KDO23598.1 - 0.031 13.6 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Ank_2 PF12796.7 KDO23599.1 - 3.1e-20 72.5 0.9 3.8e-12 46.6 0.7 3.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO23599.1 - 3.2e-15 54.7 2.0 0.055 14.0 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KDO23599.1 - 1.9e-13 50.7 6.6 3e-06 27.6 2.0 5.1 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO23599.1 - 1.9e-10 40.7 8.7 0.054 14.0 0.0 5.6 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KDO23599.1 - 6.7e-07 29.5 7.2 7e-05 23.0 0.3 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) GMP_PDE_delta PF05351.11 KDO23599.1 - 0.01 15.9 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 1 GMP-PDE, delta subunit Phos_pyr_kin PF08543.12 KDO23600.1 - 3.2e-87 292.0 3.1 5.6e-87 291.2 3.1 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KDO23600.1 - 5.7e-34 117.8 0.2 8.9e-34 117.1 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 KDO23600.1 - 3.3e-05 23.4 2.9 6.9e-05 22.3 2.9 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.24 KDO23600.1 - 0.00014 21.2 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase KH_1 PF00013.29 KDO23601.1 - 0.022 14.6 0.1 0.075 12.9 0.0 1.9 2 0 0 2 2 2 0 KH domain KH_2 PF07650.17 KDO23601.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 KH domain Nucleoside_tran PF01733.18 KDO23602.1 - 2.2e-22 79.9 11.7 9.4e-22 77.8 11.7 1.8 1 1 0 1 1 1 1 Nucleoside transporter T2SSF PF00482.23 KDO23602.1 - 0.012 15.6 1.6 0.026 14.5 1.6 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F CTV_P23 PF04808.12 KDO23602.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein DUF5556 PF17711.1 KDO23602.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5556) p25-alpha PF05517.12 KDO23603.1 - 0.0015 18.7 0.2 0.76 9.9 0.0 2.8 3 0 0 3 3 3 2 p25-alpha EF-hand_6 PF13405.6 KDO23603.1 - 0.0057 16.5 0.3 0.37 10.9 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KDO23603.1 - 0.008 16.6 0.0 0.065 13.7 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair CLP1_P PF16575.5 KDO23604.1 - 2.1e-40 138.5 0.0 3.2e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KDO23604.1 - 0.0028 17.9 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KDO23604.1 - 0.0034 16.6 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KDO23604.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ParA PF10609.9 KDO23604.1 - 0.034 13.6 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RNA_helicase PF00910.22 KDO23604.1 - 0.047 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KDO23604.1 - 0.053 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO23604.1 - 0.055 13.9 0.1 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KDO23604.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 KDO23604.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KDO23604.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PX PF00787.24 KDO23605.1 - 9.3e-10 38.5 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Ion_trans PF00520.31 KDO23606.1 - 2.9e-46 157.7 5.0 3.8e-46 157.3 5.0 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KDO23606.1 - 0.00081 18.2 9.9 1.1 7.8 3.0 3.1 2 1 1 3 3 3 3 Polycystin cation channel Fungus-induced PF10917.8 KDO23606.1 - 0.11 12.8 0.1 0.4 11.0 0.1 1.9 1 0 0 1 1 1 0 Fungus-induced protein Ion_trans PF00520.31 KDO23607.1 - 8.1e-102 339.6 55.8 4e-41 140.9 12.2 3.3 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 KDO23607.1 - 9.1e-07 27.9 48.9 0.018 13.7 1.2 7.6 5 2 2 7 7 7 6 Polycystin cation channel GPHH PF16905.5 KDO23607.1 - 1.9e-06 27.5 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated RCC1 PF00415.18 KDO23608.1 - 1.8e-62 207.8 11.8 6.4e-14 52.3 0.1 6.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO23608.1 - 3.1e-36 122.4 30.6 1.1e-09 37.8 0.6 6.9 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 KDO23608.1 - 4.5e-05 23.4 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain PBP1_TM PF14812.6 KDO23608.1 - 1.3 9.5 3.4 2.5 8.5 3.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TIG PF01833.24 KDO23609.1 - 0.00024 21.1 0.2 0.043 13.9 0.1 3.0 2 0 0 2 2 2 2 IPT/TIG domain Trypsin_2 PF13365.6 KDO23610.1 - 4.3e-15 56.9 0.1 8.6e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KDO23610.1 - 0.39 9.3 2.4 5.4 5.5 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 zf-CCCH PF00642.24 KDO23611.1 - 2.9e-09 36.6 2.6 2.9e-09 36.6 2.6 2.7 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KDO23611.1 - 2.4e-06 27.3 6.0 4.7e-06 26.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO23611.1 - 6e-06 26.2 7.1 1.5e-05 24.9 7.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KDO23611.1 - 7.7e-06 26.2 8.5 7.7e-06 26.2 8.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf_CCCH_4 PF18345.1 KDO23611.1 - 6e-05 23.0 5.0 6e-05 23.0 5.0 2.0 2 0 0 2 2 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KDO23611.1 - 0.00016 21.5 10.0 0.00037 20.3 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO23611.1 - 0.00022 21.1 11.3 0.0005 20.0 11.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KDO23611.1 - 0.00031 20.5 9.1 0.00071 19.4 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 KDO23611.1 - 0.0027 17.5 3.3 0.0027 17.5 3.3 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KDO23611.1 - 0.0098 16.0 5.4 0.0098 16.0 5.4 2.0 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KDO23611.1 - 0.019 15.1 4.6 0.019 15.1 4.6 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KDO23611.1 - 0.039 13.8 6.4 0.091 12.6 6.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KDO23611.1 - 0.16 12.2 8.9 0.55 10.4 8.9 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-CCCH_2 PF14608.6 KDO23611.1 - 5.1 7.7 9.6 0.51 10.9 4.2 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TACC_C PF05010.14 KDO23612.1 - 7e-06 26.0 23.8 7e-06 26.0 23.8 8.2 2 2 5 8 8 8 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 KDO23612.1 - 0.00033 19.4 13.3 0.00033 19.4 13.3 7.4 1 1 6 7 7 7 1 AAA domain HALZ PF02183.18 KDO23612.1 - 0.0078 16.4 3.1 0.0078 16.4 3.1 13.2 14 2 2 16 16 16 1 Homeobox associated leucine zipper DUF1664 PF07889.12 KDO23612.1 - 0.032 14.3 93.1 0.015 15.4 3.5 12.8 5 5 8 14 14 14 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 KDO23612.1 - 0.049 13.9 0.4 0.049 13.9 0.4 12.2 2 1 9 12 12 12 0 Tho complex subunit 7 Filament PF00038.21 KDO23612.1 - 0.86 9.1 164.1 0.0082 15.8 32.0 8.5 1 1 6 7 7 7 0 Intermediate filament protein SH3_4 PF06347.13 KDO23613.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain L51_S25_CI-B8 PF05047.16 KDO23615.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SUI1 PF01253.22 KDO23616.1 - 3.1e-23 82.1 0.8 3.8e-23 81.8 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2997 PF11211.8 KDO23616.1 - 0.026 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Neuropeptide_S PF14993.6 KDO23617.1 - 0.028 14.2 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein CENP-B_dimeris PF09026.10 KDO23617.1 - 0.11 12.9 9.1 0.37 11.2 9.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WSD PF15613.6 KDO23617.1 - 5.6 7.5 9.9 0.99 9.9 4.1 2.7 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif SKN1 PF03935.15 KDO23620.1 - 1.7e-56 191.7 24.9 7.4e-24 84.0 1.3 5.2 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO23620.1 - 0.056 13.8 4.1 0.033 14.5 1.5 2.0 2 0 0 2 2 2 0 EB module Nodulin_late PF07127.11 KDO23620.1 - 0.083 13.2 0.8 0.23 11.9 0.8 1.7 1 0 0 1 1 1 0 Late nodulin protein SKN1 PF03935.15 KDO23621.1 - 6e-58 196.5 18.8 2.7e-26 92.1 0.5 5.2 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO23621.1 - 0.031 14.6 1.3 0.031 14.6 1.3 2.1 2 0 0 2 2 2 0 EB module Nodulin_late PF07127.11 KDO23621.1 - 0.15 12.4 0.6 0.37 11.1 0.6 1.6 1 0 0 1 1 1 0 Late nodulin protein PH PF00169.29 KDO23622.1 - 0.00017 22.0 0.0 0.0003 21.3 0.0 1.3 1 0 0 1 1 1 1 PH domain IQ PF00612.27 KDO23622.1 - 0.012 15.3 1.4 0.034 13.9 1.4 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Antifungal_prot PF11402.8 KDO23624.1 - 0.0087 16.3 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Antifungal protein TPT PF03151.16 KDO23626.1 - 9.6e-49 166.3 22.9 1.2e-48 166.0 22.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KDO23626.1 - 4.7e-08 33.3 28.8 0.00014 22.0 8.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KDO23626.1 - 0.0014 17.9 21.3 0.0051 16.0 21.3 1.8 1 1 0 1 1 1 1 UAA transporter family Bromo_coat PF01318.18 KDO23626.1 - 0.071 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Bromovirus coat protein CBFD_NFYB_HMF PF00808.23 KDO23627.1 - 2.5e-22 78.9 1.0 5.8e-22 77.8 1.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.20 KDO23627.1 - 1.8e-16 60.3 0.0 4.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain Histone PF00125.24 KDO23627.1 - 2.6e-16 60.2 2.6 4.9e-16 59.3 2.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CRAL_TRIO_2 PF13716.6 KDO23627.1 - 0.011 15.9 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Reticulon PF02453.17 KDO23627.1 - 0.89 9.5 8.1 48 3.9 0.0 3.2 2 0 0 2 2 2 0 Reticulon COPI_assoc PF08507.10 KDO23628.1 - 1.9e-05 24.7 10.3 2.6e-05 24.3 10.3 1.2 1 0 0 1 1 1 1 COPI associated protein Pkinase_Tyr PF07714.17 KDO23629.1 - 2.3e-41 141.8 0.0 2.8e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO23629.1 - 3.6e-29 101.9 0.0 4.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23630.1 - 1.4e-56 191.7 0.0 1.7e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO23630.1 - 2.5e-49 168.0 0.0 3.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO23630.1 - 0.047 12.6 0.0 0.57 9.1 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain SAS-6_N PF16531.5 KDO23631.1 - 5.6e-28 97.4 0.3 5.6e-28 97.4 0.3 3.1 3 1 0 3 3 3 1 Centriolar protein SAS N-terminal UCH PF00443.29 KDO23632.1 - 1.6e-35 122.9 0.0 2.7e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO23632.1 - 1.9e-14 54.0 0.0 4.3e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FoP_duplication PF13865.6 KDO23633.1 - 4.9e-18 65.5 16.7 9e-18 64.6 16.7 1.5 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Pec_lyase_N PF04431.13 KDO23633.1 - 0.16 12.2 6.7 2.2 8.6 0.2 2.4 1 1 1 2 2 2 0 Pectate lyase, N terminus DUF308 PF03729.13 KDO23634.1 - 0.0043 17.3 0.3 0.0043 17.3 0.3 3.3 3 1 0 3 3 3 1 Short repeat of unknown function (DUF308) DUF1673 PF07895.11 KDO23634.1 - 0.21 11.3 4.8 0.35 10.5 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2678 PF10856.8 KDO23634.1 - 0.26 11.2 3.1 0.45 10.5 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Rad60-SLD_2 PF13881.6 KDO23635.1 - 3.3e-13 49.7 0.0 3.5e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_2 PF13639.6 KDO23636.1 - 8.1e-06 26.1 8.3 1.9e-05 24.9 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KDO23636.1 - 0.00025 21.0 2.5 0.00058 19.9 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KDO23636.1 - 0.0011 19.2 5.6 0.0027 17.9 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KDO23636.1 - 0.0015 18.6 5.7 0.0038 17.3 5.7 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KDO23636.1 - 0.0055 16.8 8.0 0.014 15.5 8.0 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 KDO23636.1 - 0.011 15.6 0.2 0.011 15.6 0.2 2.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KDO23636.1 - 0.027 14.1 2.7 0.066 12.8 2.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KDO23636.1 - 0.06 13.2 10.9 0.12 12.3 10.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OpuAC PF04069.12 KDO23636.1 - 0.083 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system zf-C3HC4_2 PF13923.6 KDO23636.1 - 0.11 12.4 8.9 0.27 11.1 8.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3837 PF12939.7 KDO23636.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) Zf_RING PF16744.5 KDO23636.1 - 0.27 11.4 2.2 0.98 9.6 2.2 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 KDO23636.1 - 0.28 11.5 11.7 0.083 13.2 6.6 2.4 2 0 0 2 2 2 0 RING-like domain Dus PF01207.17 KDO23637.1 - 1.6e-54 185.1 0.1 7.1e-54 183.0 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2_jaz PF12171.8 KDO23637.1 - 0.00089 19.5 0.5 0.002 18.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding NMO PF03060.15 KDO23637.1 - 0.011 15.1 0.2 0.04 13.3 0.1 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase zf-U1 PF06220.12 KDO23637.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 U1 zinc finger SpoIISA_toxin PF14171.6 KDO23637.1 - 0.13 11.9 0.0 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system zf-met PF12874.7 KDO23637.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type LRR_6 PF13516.6 KDO23638.1 - 0.76 10.0 2.2 72 3.8 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat DUF5311 PF17238.2 KDO23639.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) PROCN PF08083.11 KDO23641.1 - 1.5e-236 784.7 6.9 2.3e-236 784.1 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KDO23641.1 - 1.2e-126 420.9 0.5 2e-126 420.2 0.5 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KDO23641.1 - 6e-90 299.3 2.3 1.4e-89 298.1 2.3 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KDO23641.1 - 2.4e-87 290.6 4.3 4.1e-87 289.8 3.4 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KDO23641.1 - 1e-72 242.5 0.1 2e-72 241.6 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KDO23641.1 - 2.4e-51 172.8 0.1 5.8e-51 171.6 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KDO23641.1 - 1.5e-46 156.7 0.5 3.8e-46 155.4 0.5 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KDO23641.1 - 3.4e-07 30.3 0.0 8.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4954 PF16314.5 KDO23642.1 - 3e-44 151.2 0.0 4.1e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Chloroplast_duf PF14476.6 KDO23642.1 - 0.15 11.0 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Petal formation-expressed FYVE PF01363.21 KDO23643.1 - 4.3e-15 55.6 13.6 4.3e-15 55.6 13.6 2.5 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO23643.1 - 5.3e-12 45.9 9.7 5.3e-12 45.9 9.7 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO23643.1 - 2.9e-09 36.6 9.3 2.9e-09 36.6 9.3 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO23643.1 - 7.8e-07 29.3 13.0 7.8e-07 29.3 13.0 3.4 2 2 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO23643.1 - 1.8e-06 27.5 10.3 1.8e-06 27.5 10.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO23643.1 - 2.8e-06 27.2 8.0 2.8e-06 27.2 8.0 3.1 2 1 2 4 4 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO23643.1 - 6e-06 26.2 4.1 6e-06 26.2 4.1 3.3 2 2 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO23643.1 - 8.2e-06 25.6 8.7 8.2e-06 25.6 8.7 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO23643.1 - 7.7e-05 22.5 5.4 7.7e-05 22.5 5.4 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO23643.1 - 0.0032 17.5 8.6 0.0032 17.5 8.6 2.9 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DpnI PF06044.12 KDO23643.1 - 0.59 9.7 4.9 0.39 10.3 2.6 1.7 2 0 0 2 2 2 0 Dam-replacing family zf_C2HC_14 PF18574.1 KDO23643.1 - 6.4 6.7 17.5 0.12 12.2 7.6 2.9 3 0 0 3 3 3 0 C2HC Zing finger domain FYVE PF01363.21 KDO23644.1 - 2.4e-12 46.8 26.3 1.5e-11 44.2 26.3 2.5 1 1 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO23644.1 - 1.1e-10 41.7 7.3 1.1e-10 41.7 7.3 3.1 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO23644.1 - 2.1e-08 33.9 7.6 2.1e-08 33.9 7.6 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO23644.1 - 3.7e-06 26.6 2.2 3.7e-06 26.6 2.2 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO23644.1 - 7.7e-06 25.7 5.2 7.7e-06 25.7 5.2 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO23644.1 - 1.6e-05 25.1 9.4 1.6e-05 25.1 9.4 3.5 2 2 1 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO23644.1 - 0.00039 20.3 7.4 0.00039 20.3 7.4 3.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO23644.1 - 0.0035 17.4 2.1 0.0035 17.4 2.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.16 KDO23644.1 - 0.0085 16.3 8.8 0.0085 16.3 8.8 1.9 2 1 0 2 2 2 1 FYVE-type zinc finger DZR PF12773.7 KDO23644.1 - 0.9 9.6 22.5 1.8e+04 -6.0 22.5 3.5 1 1 0 1 1 0 0 Double zinc ribbon zinc_ribbon_16 PF17034.5 KDO23644.1 - 2.6 8.3 18.9 0.082 13.1 2.8 2.6 3 0 0 3 3 3 0 Zinc-ribbon like family Stealth_CR2 PF11380.8 KDO23647.1 - 1.3e-33 115.4 0.0 2.9e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KDO23647.1 - 6.9e-08 32.1 0.0 1.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KDO23647.1 - 2.9e-07 30.3 0.4 5.8e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KDO23647.1 - 3.4e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR2 PF11380.8 KDO23648.1 - 6.8e-34 116.3 0.1 1.7e-33 115.0 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KDO23648.1 - 2.1e-10 40.3 3.3 4.7e-10 39.2 3.3 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 KDO23648.1 - 2.5e-07 30.3 0.0 5.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 KDO23648.1 - 3.7e-07 29.9 0.1 8.5e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 NDUF_B12 PF08122.12 KDO23648.1 - 0.17 12.0 0.2 0.39 10.8 0.2 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family PTPlike_phytase PF14566.6 KDO23649.1 - 3.8e-67 225.3 0.0 9.3e-38 129.8 0.0 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate DSPc PF00782.20 KDO23649.1 - 0.0038 17.0 0.0 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain IQ PF00612.27 KDO23649.1 - 0.041 13.7 0.5 0.13 12.1 0.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif WD40 PF00400.32 KDO23650.1 - 1.1e-14 54.5 5.0 7e-07 29.8 0.1 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO23650.1 - 2e-06 28.0 0.0 0.028 14.7 0.0 3.5 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO23650.1 - 0.011 14.4 0.2 0.079 11.6 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Sema PF01403.19 KDO23650.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Sema domain TPK_catalytic PF04263.16 KDO23652.1 - 7.1e-36 122.9 0.0 5.2e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KDO23652.1 - 7.8e-17 60.8 0.0 1.1e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Myb_DNA-binding PF00249.31 KDO23654.1 - 4.7e-18 65.1 1.5 7.2e-13 48.5 0.5 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO23654.1 - 2.3e-14 53.4 0.0 1.2e-12 47.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO23654.1 - 0.00088 19.6 3.4 0.26 11.7 0.3 2.8 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain AAA_25 PF13481.6 KDO23655.1 - 6.6e-19 68.3 0.0 1.5e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KDO23655.1 - 6.9e-15 55.0 0.1 1.7e-06 27.6 0.0 2.1 1 1 1 2 2 2 2 KaiC DnaB_C PF03796.15 KDO23655.1 - 8.8e-11 41.6 0.7 5.9e-06 25.8 0.2 2.3 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain Rubredoxin_2 PF18073.1 KDO23655.1 - 5.9e-10 38.7 5.4 9.9e-10 38.0 5.4 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 KDO23655.1 - 1.3e-09 37.9 0.0 3.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 KDO23655.1 - 7.8e-08 32.1 0.3 1.6e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain Rad51 PF08423.11 KDO23655.1 - 7.5e-07 28.7 0.0 3.2e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Rad51 AAA PF00004.29 KDO23655.1 - 1.5e-05 25.4 0.1 3.8e-05 24.1 0.1 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KDO23655.1 - 2.3e-05 24.2 0.0 0.0002 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KDO23655.1 - 6.3e-05 22.4 0.0 8.2e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KDO23655.1 - 0.00094 19.5 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain GvpD PF07088.11 KDO23655.1 - 0.003 16.3 0.0 0.021 13.5 0.0 1.9 1 1 0 1 1 1 1 GvpD gas vesicle protein AAA_18 PF13238.6 KDO23655.1 - 0.0049 17.4 0.0 0.0095 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KDO23655.1 - 0.0059 16.1 0.3 0.0096 15.4 0.3 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 KDO23655.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KDO23655.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO23655.1 - 0.046 13.4 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KDO23655.1 - 0.068 12.9 0.2 0.15 11.8 0.2 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KDO23655.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KDO23655.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KDO23655.1 - 0.072 12.8 0.5 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KDO23655.1 - 0.09 13.2 0.0 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.10 KDO23655.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 KDO23655.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO23655.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Acetyltransf_1 PF00583.25 KDO23656.1 - 1.9e-11 44.2 0.0 5.1e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO23656.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO23656.1 - 1.6e-05 25.3 0.0 4.9e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KDO23656.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO23656.1 - 0.0013 18.7 0.1 0.0036 17.2 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 KDO23656.1 - 0.0013 19.4 0.1 0.003 18.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KDO23656.1 - 0.0031 17.2 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KDO23657.1 - 1.1e-65 221.6 0.0 1.7e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23657.1 - 1e-42 146.2 0.0 1.5e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ATG11 PF10377.9 KDO23657.1 - 1.4e-30 106.0 0.0 2.5e-17 63.1 0.0 2.9 3 0 0 3 3 3 2 Autophagy-related protein 11 ABC1 PF03109.16 KDO23657.1 - 0.0036 17.5 0.0 0.0073 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Kdo PF06293.14 KDO23657.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO23657.1 - 0.02 14.8 0.0 0.14 12.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO23657.1 - 0.049 12.9 0.0 0.094 12.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 KDO23657.1 - 0.058 12.9 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL GSP_synth PF03738.14 KDO23658.1 - 2.9e-67 227.5 0.0 3.6e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp Zip PF02535.22 KDO23659.1 - 0.0035 16.6 6.4 0.011 15.0 6.4 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4364 PF14277.6 KDO23659.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) FixQ PF05545.11 KDO23659.1 - 4.4 7.4 5.6 5.3 7.1 0.2 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Hid1 PF12722.7 KDO23659.1 - 6.1 4.8 5.9 8.4 4.4 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Fungal_KA1 PF16797.5 KDO23660.1 - 0.033 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Cwf_Cwc_15 PF04889.12 KDO23661.1 - 0.95 9.1 9.7 0.57 9.9 4.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 KDO23661.1 - 5.8 7.4 11.3 1.4 9.3 4.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PDZ_6 PF17820.1 KDO23662.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KDO23662.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Carn_acyltransf PF00755.20 KDO23663.1 - 1.4e-178 595.2 0.0 1.6e-178 595.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase PF00069.25 KDO23665.1 - 1e-39 136.5 0.0 9e-27 94.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23665.1 - 4.6e-22 78.5 0.0 2.7e-14 53.1 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 KDO23665.1 - 0.00025 20.7 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KDO23665.1 - 0.00039 19.8 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO23665.1 - 0.00056 19.3 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO23665.1 - 0.028 13.2 2.2 0.053 12.3 2.2 1.6 1 1 0 1 1 1 0 Fungal protein kinase HAT PF02184.16 KDO23666.1 - 1.5e-24 85.6 72.9 1.5e-05 24.9 1.5 15.6 15 2 0 15 15 15 6 HAT (Half-A-TPR) repeat Suf PF05843.14 KDO23666.1 - 2.5e-16 60.5 29.3 0.00071 19.6 0.2 6.3 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KDO23666.1 - 6.2e-15 54.6 37.5 0.012 16.4 0.4 13.2 6 5 8 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.6 KDO23666.1 - 1.2e-11 45.0 5.8 0.057 13.9 0.0 6.2 5 1 2 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KDO23666.1 - 6.4e-09 35.6 1.3 0.43 11.1 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KDO23666.1 - 1e-05 25.5 31.8 0.048 13.7 0.7 7.7 7 0 0 7 7 7 4 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 KDO23666.1 - 4.8e-05 23.9 24.0 0.0084 16.7 0.0 7.5 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO23666.1 - 5e-05 23.5 20.0 1.2 9.5 0.0 7.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23666.1 - 0.00052 19.9 22.0 2.9 8.2 0.2 9.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO23666.1 - 0.013 16.0 28.4 1.7 9.5 0.7 10.3 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO23666.1 - 0.076 13.2 0.1 0.076 13.2 0.1 5.7 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO23666.1 - 3.7 8.0 17.4 23 5.5 0.1 7.0 9 0 0 9 9 8 0 Tetratricopeptide repeat PX PF00787.24 KDO23667.1 - 1.4e-06 28.3 0.0 7.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 PX domain PDZ_6 PF17820.1 KDO23667.1 - 0.022 14.6 0.0 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 PDZ domain PQQ_3 PF13570.6 KDO23668.1 - 5e-05 23.6 4.2 0.96 10.0 0.0 5.1 4 1 1 5 5 5 2 PQQ-like domain SGL PF08450.12 KDO23668.1 - 0.00027 20.6 2.0 0.3 10.6 0.0 4.4 3 2 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 KDO23668.1 - 0.00045 20.6 4.4 2.5 8.7 0.2 5.1 6 0 0 6 6 6 2 Low-density lipoprotein receptor repeat class B TIG PF01833.24 KDO23668.1 - 0.0075 16.3 0.2 0.031 14.3 0.2 2.1 2 0 0 2 2 2 1 IPT/TIG domain Mab-21 PF03281.14 KDO23669.1 - 0.026 13.8 0.1 0.029 13.7 0.1 1.0 1 0 0 1 1 1 0 Mab-21 protein Thioredoxin PF00085.20 KDO23670.1 - 2.2e-32 111.1 0.1 3.4e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO23670.1 - 1.7e-06 28.4 0.3 6.9e-06 26.5 0.2 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KDO23670.1 - 0.0006 19.3 0.0 0.00084 18.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KDO23670.1 - 0.0049 17.2 0.0 0.36 11.2 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 KDO23670.1 - 0.0055 16.6 0.0 0.076 12.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KDO23670.1 - 0.04 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 KDO23670.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 KDO23670.1 - 0.13 12.0 0.0 4.1 7.1 0.1 2.4 2 1 1 3 3 3 0 Thioredoxin Proteasome PF00227.26 KDO23671.1 - 1.2e-13 51.0 0.1 1.3e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit MciZ PF13072.6 KDO23671.1 - 0.05 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Arena_glycoprot PF00798.18 KDO23672.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 Arenavirus glycoprotein Na_Pi_cotrans PF02690.15 KDO23673.1 - 5e-38 130.3 24.8 7.6e-20 71.4 5.0 2.7 3 0 0 3 3 3 2 Na+/Pi-cotransporter LRR_6 PF13516.6 KDO23674.1 - 0.004 17.1 0.0 0.76 10.0 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat Glyco_hydro_cc PF11790.8 KDO23675.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core ADIP PF11559.8 KDO23677.1 - 1e-06 28.9 5.2 1e-06 28.9 5.2 3.8 3 1 0 3 3 3 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KDO23677.1 - 0.0052 16.9 11.8 0.0052 16.9 11.8 4.9 4 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KDO23677.1 - 0.52 10.7 32.9 0.025 15.0 8.6 2.8 3 0 0 3 3 3 0 Fez1 Glyco_hydro_3 PF00933.21 KDO23678.1 - 1.5e-45 155.9 0.0 2.3e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KDO23678.1 - 5.5e-41 140.8 0.0 9e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KDO23678.1 - 4.4e-08 33.1 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain zf-C3HC4_3 PF13920.6 KDO23679.1 - 2.6e-10 40.0 11.7 5.1e-10 39.1 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO23679.1 - 2e-09 37.7 12.2 4.4e-09 36.5 12.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO23679.1 - 2.5e-09 36.8 12.7 5.4e-09 35.8 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO23679.1 - 6.5e-08 32.3 12.0 1.6e-07 31.1 12.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO23679.1 - 9.3e-07 28.6 12.3 1.7e-06 27.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO23679.1 - 1.2e-06 28.4 11.0 2.8e-06 27.2 11.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KDO23679.1 - 2.6e-06 27.6 8.4 5.8e-06 26.5 8.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO23679.1 - 6.3e-06 26.1 5.1 6.3e-06 26.1 5.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO23679.1 - 0.0028 17.8 10.7 0.0068 16.5 10.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO23679.1 - 0.011 15.5 8.8 0.027 14.2 8.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KDO23679.1 - 0.013 15.1 7.3 0.013 15.1 7.3 1.8 2 0 0 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KDO23679.1 - 0.03 14.4 6.0 0.071 13.2 6.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 KDO23679.1 - 0.35 10.5 7.3 0.81 9.3 2.3 2.7 2 0 0 2 2 2 0 RecR protein zf-RING_11 PF17123.5 KDO23679.1 - 3.2 7.6 13.7 0.12 12.2 6.5 2.4 2 0 0 2 2 2 0 RING-like zinc finger PIN_11 PF18479.1 KDO23680.1 - 0.011 15.9 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 PIN like domain WW PF00397.26 KDO23680.1 - 0.012 15.7 1.3 0.012 15.7 1.3 2.5 2 0 0 2 2 2 0 WW domain PP2C PF00481.21 KDO23681.1 - 1.4e-35 123.2 0.0 1.7e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO23681.1 - 0.00011 22.0 0.5 0.00035 20.3 0.5 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C BacteriocIIc_cy PF12173.8 KDO23682.1 - 0.24 11.7 3.5 0.3 11.4 0.6 2.3 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like Peptidase_S8 PF00082.22 KDO23683.1 - 1.4e-25 90.2 0.0 1.8e-14 53.7 0.1 2.6 1 1 1 2 2 2 2 Subtilase family Ricin_B_lectin PF00652.22 KDO23683.1 - 2.9e-15 56.7 8.7 8.5e-12 45.4 2.9 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO23683.1 - 5.4e-05 23.9 6.7 0.0043 17.7 0.1 4.0 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like DUF4777 PF16007.5 KDO23683.1 - 0.17 12.2 0.0 0.49 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) HSP70 PF00012.20 KDO23685.1 - 3.3e-134 448.3 0.1 1.7e-126 422.8 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KDO23685.1 - 1.1e-10 40.9 0.1 9.7e-10 37.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KDO23685.1 - 0.037 14.4 0.3 18 5.8 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA Raco_middle PF17651.1 KDO23685.1 - 0.11 12.1 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 RACo middle region SLED PF12140.8 KDO23688.1 - 0.18 12.3 0.1 4.2 7.9 0.0 2.8 2 1 0 2 2 2 0 SLED domain LRR_6 PF13516.6 KDO23688.1 - 2.7 8.3 5.8 3.1 8.1 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Kei1 PF08552.11 KDO23689.1 - 0.016 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SKG6 PF08693.10 KDO23690.1 - 0.00017 20.9 1.3 0.00034 20.0 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KDO23690.1 - 0.0027 17.8 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Podoplanin PGF-CTERM PF18204.1 KDO23690.1 - 0.11 12.5 3.6 0.27 11.3 3.6 1.7 1 0 0 1 1 1 0 PGF-CTERM motif DHHC PF01529.20 KDO23691.1 - 4.3e-20 72.2 9.7 4.3e-20 72.2 9.7 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3440 PF11922.8 KDO23691.1 - 0.2 11.3 2.3 0.13 11.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Aa_trans PF01490.18 KDO23692.1 - 2.6e-36 125.2 39.3 2.8e-21 75.7 16.5 2.9 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein RabGAP-TBC PF00566.18 KDO23694.1 - 1.1e-17 64.4 0.8 1.5e-17 64.0 0.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YscK PF06578.12 KDO23696.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.0 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) PP2C PF00481.21 KDO23697.1 - 1.2e-67 228.3 0.0 1.4e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 KDO23697.1 - 6.8e-14 52.0 0.0 2.8e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KDO23697.1 - 1.7e-06 28.2 0.0 6.2e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PP2C_2 PF13672.6 KDO23697.1 - 6.9e-06 25.8 0.0 1.6e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO23697.1 - 0.0039 17.1 0.9 0.22 11.4 0.2 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) HSP70 PF00012.20 KDO23698.1 - 7.5e-83 278.7 4.2 8.3e-83 278.6 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF4635 PF15466.6 KDO23698.1 - 0.018 14.5 0.6 0.037 13.6 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) FGGY_C PF02782.16 KDO23698.1 - 0.037 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SHS2_FTSA PF02491.20 KDO23698.1 - 0.054 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA YlmH_RBD PF17774.1 KDO23698.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH HSP70 PF00012.20 KDO23699.1 - 1.5e-215 716.9 14.5 8.5e-215 714.5 14.5 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO23699.1 - 1.6e-09 37.1 1.5 3.1e-08 32.8 0.5 2.6 2 1 0 2 2 2 1 MreB/Mbl protein TPR_2 PF07719.17 KDO23699.1 - 1.8e-09 37.0 11.7 0.0015 18.4 0.7 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO23699.1 - 9.8e-09 34.7 11.7 0.00024 20.8 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO23699.1 - 1.1e-06 28.4 9.7 0.069 13.4 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO23699.1 - 0.0014 18.8 8.4 0.84 10.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KDO23699.1 - 0.0022 18.3 0.1 0.0076 16.6 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO23699.1 - 0.0034 17.0 3.2 0.0034 17.0 3.2 3.0 1 1 2 3 3 3 1 TPR repeat TPR_16 PF13432.6 KDO23699.1 - 0.0036 17.9 5.9 0.0036 17.9 5.9 3.2 2 1 2 4 4 4 1 Tetratricopeptide repeat DDR PF08841.10 KDO23699.1 - 0.0051 15.8 0.2 0.024 13.7 0.1 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 KDO23699.1 - 0.0056 17.1 3.2 4 7.9 0.1 3.7 3 0 0 3 3 3 1 Cell division protein FtsA TPR_19 PF14559.6 KDO23699.1 - 0.012 16.1 8.1 0.37 11.3 2.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO23699.1 - 0.013 15.8 7.6 0.37 11.1 2.5 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat SHS2_FTSA PF02491.20 KDO23699.1 - 0.024 15.0 0.3 0.09 13.2 0.3 2.0 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA TPR_7 PF13176.6 KDO23699.1 - 0.076 13.1 1.4 20 5.5 0.1 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF4635 PF15466.6 KDO23699.1 - 0.077 12.5 0.8 0.15 11.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) TPR_14 PF13428.6 KDO23699.1 - 2 9.4 10.6 3.3 8.8 0.1 4.6 3 1 2 5 5 3 0 Tetratricopeptide repeat Beach PF02138.18 KDO23700.1 - 2.6e-116 387.8 0.0 3.8e-116 387.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KDO23700.1 - 5.3e-16 58.6 0.0 1.2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KDO23700.1 - 1.4e-09 37.7 2.1 2.7e-09 36.7 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 KDO23700.1 - 1.9e-08 34.6 0.0 3.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KDO23700.1 - 0.0072 17.2 2.3 0.091 13.7 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat PTR2 PF00854.21 KDO23701.1 - 7.1e-86 288.5 5.3 1.4e-85 287.5 5.3 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KDO23701.1 - 1.1e-09 37.8 42.3 8.7e-08 31.5 15.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily IU_nuc_hydro PF01156.19 KDO23702.1 - 5.4e-64 216.7 0.1 6e-64 216.5 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HEM4 PF02602.15 KDO23702.1 - 0.036 13.4 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD YjbR PF04237.13 KDO23702.1 - 0.14 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 YjbR IU_nuc_hydro PF01156.19 KDO23703.1 - 1.8e-65 221.6 0.3 2e-65 221.4 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HEM4 PF02602.15 KDO23703.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Baculo_PEP_C PF04513.12 KDO23705.1 - 0.009 16.1 1.2 1.5 8.9 0.4 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 KDO23705.1 - 0.043 13.6 0.1 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Laminin_II PF06009.12 KDO23705.1 - 0.049 13.6 0.1 1.2 9.2 0.1 2.3 1 1 1 2 2 2 0 Laminin Domain II SOG2 PF10428.9 KDO23705.1 - 0.1 11.8 6.5 0.12 11.5 6.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein BLOC1S3 PF15753.5 KDO23705.1 - 2.3 8.3 6.6 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Nucleoside_tran PF01733.18 KDO23706.1 - 3e-16 59.7 19.2 6.6e-13 48.7 6.5 2.9 2 1 1 3 3 3 2 Nucleoside transporter Nucleoside_tran PF01733.18 KDO23707.1 - 2.6e-20 73.0 21.1 1.8e-18 67.0 21.1 2.2 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KDO23707.1 - 0.00039 19.5 44.4 0.012 14.5 42.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF443 PF04276.12 KDO23707.1 - 0.035 13.9 3.0 0.14 11.9 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Nucleoside_tran PF01733.18 KDO23708.1 - 7.9e-19 68.2 15.0 6.8e-15 55.2 3.0 2.5 1 1 1 2 2 2 2 Nucleoside transporter EF-hand_6 PF13405.6 KDO23709.1 - 1.4e-06 27.8 0.0 5.8e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KDO23709.1 - 7.1e-06 26.4 0.1 2.2e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO23709.1 - 9.5e-06 24.8 0.0 2.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KDO23709.1 - 0.0004 19.8 0.0 0.0014 18.0 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KDO23709.1 - 0.00062 19.6 0.1 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair CDC24_OB3 PF17244.2 KDO23709.1 - 0.2 11.4 0.6 0.66 9.6 0.2 2.0 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 CSRNP_N PF16019.5 KDO23710.1 - 0.012 15.6 0.7 0.036 14.0 0.7 1.9 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CTP_transf_like PF01467.26 KDO23710.1 - 0.031 14.4 0.1 0.041 14.1 0.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase-like DUF2407_C PF13373.6 KDO23710.1 - 0.041 14.1 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain TPR_2 PF07719.17 KDO23711.1 - 2.6e-13 49.0 3.5 0.00014 21.7 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO23711.1 - 7.6e-13 47.7 2.4 0.00078 19.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO23711.1 - 6.8e-06 25.7 1.3 0.13 12.0 0.0 2.7 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 KDO23711.1 - 0.00056 20.2 4.2 0.0079 16.5 0.9 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Bap31_Bap29_C PF18035.1 KDO23711.1 - 0.00077 19.4 1.6 0.0019 18.2 1.6 1.7 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain TPR_8 PF13181.6 KDO23711.1 - 0.0015 18.6 5.4 0.055 13.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO23711.1 - 0.0066 16.3 0.3 0.0066 16.3 0.3 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO23711.1 - 0.024 14.6 0.9 7.6 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Baculo_gp41 PF04700.12 KDO23711.1 - 0.027 14.2 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region TPR_9 PF13371.6 KDO23711.1 - 0.038 14.1 1.2 1.1 9.4 1.7 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-UBP_var PF17807.1 KDO23711.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger Csm1_N PF18504.1 KDO23711.1 - 0.16 12.4 3.4 11 6.5 0.3 2.9 3 1 1 4 4 3 0 Csm1 N-terminal domain TPR_16 PF13432.6 KDO23711.1 - 0.21 12.3 6.9 3.2 8.5 5.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23711.1 - 0.3 12.0 5.0 1.1 10.3 0.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KDO23712.1 - 3.6e-117 391.5 0.0 4.5e-117 391.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KDO23712.1 - 0.033 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase DXPR_C PF13288.6 KDO23712.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain Adaptin_N PF01602.20 KDO23714.1 - 9.1e-114 380.9 0.3 1.1e-113 380.6 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KDO23714.1 - 2.1e-17 63.3 0.0 5.4e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KDO23714.1 - 7.9e-14 51.9 0.1 1.7e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KDO23714.1 - 8.2e-07 29.2 0.3 2.5e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 KDO23714.1 - 0.0064 15.1 0.2 0.011 14.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT PF02985.22 KDO23714.1 - 0.0069 16.6 2.1 4.5 7.8 0.1 3.9 3 0 0 3 3 3 2 HEAT repeat Ank_2 PF12796.7 KDO23715.1 - 1.6e-22 79.9 0.2 6.3e-09 36.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23715.1 - 9.4e-19 67.5 0.4 5.7e-06 26.8 0.0 4.9 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23715.1 - 3.2e-15 56.0 1.5 1.4e-05 25.3 0.0 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23715.1 - 1.2e-13 49.8 0.9 0.05 14.2 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KDO23715.1 - 2.6e-09 37.1 0.9 1.5 9.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat TPR_12 PF13424.6 KDO23715.1 - 1.2e-08 35.1 0.3 1.2e-06 28.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO23715.1 - 3.1e-06 26.8 4.2 5.4e-05 22.9 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat zf-B_box PF00643.24 KDO23715.1 - 0.00028 20.9 4.0 0.00075 19.6 4.0 1.7 1 0 0 1 1 1 1 B-box zinc finger RGS PF00615.19 KDO23715.1 - 0.00037 20.8 0.1 0.00064 20.0 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain TPR_19 PF14559.6 KDO23715.1 - 0.007 16.8 0.5 0.6 10.7 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO23715.1 - 0.062 13.1 1.8 12 5.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CEBP_ZZ PF16366.5 KDO23715.1 - 0.2 11.9 2.6 0.48 10.7 2.6 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TPR_7 PF13176.6 KDO23715.1 - 0.26 11.4 4.6 2.2 8.5 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO23715.1 - 0.52 10.7 2.2 3.4 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23715.1 - 4.8 8.3 10.6 12 7.0 0.1 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat ARL2_Bind_BART PF11527.8 KDO23716.1 - 7.2e-10 39.0 0.2 9.2e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Arf PF00025.21 KDO23717.1 - 6.7e-52 175.5 0.1 7.9e-52 175.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KDO23717.1 - 2e-15 56.7 0.0 2.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KDO23717.1 - 1.4e-14 54.0 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23717.1 - 3.3e-13 49.9 0.0 4.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KDO23717.1 - 1.7e-12 47.2 2.2 1.7e-07 30.8 1.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO23717.1 - 1.3e-08 35.0 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO23717.1 - 2e-08 33.9 0.1 2.4e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KDO23717.1 - 2.2e-05 24.1 0.2 0.0063 16.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KDO23717.1 - 0.00061 19.3 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO23717.1 - 0.0017 18.3 0.1 0.19 11.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KDO23717.1 - 0.0029 17.4 0.4 0.3 10.8 0.2 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KDO23717.1 - 0.003 18.1 0.0 0.0045 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KDO23717.1 - 0.018 14.8 0.1 0.17 11.6 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KDO23717.1 - 0.04 14.0 0.1 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 KDO23717.1 - 0.066 13.5 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PTPS_related PF10131.9 KDO23717.1 - 0.067 11.5 0.0 0.081 11.2 0.0 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Thymidylate_kin PF02223.17 KDO23717.1 - 0.068 12.8 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DAP3 PF10236.9 KDO23717.1 - 0.075 12.2 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MobB PF03205.14 KDO23717.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KDO23717.1 - 0.15 12.4 0.1 0.19 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KDO23717.1 - 0.2 11.2 1.1 2 8.0 0.1 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CENP-F_leu_zip PF10473.9 KDO23718.1 - 0.015 15.3 1.6 0.015 15.3 1.6 4.7 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ING PF12998.7 KDO23718.1 - 6.3 7.4 15.9 0.66 10.6 2.0 4.3 3 3 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding IFT43 PF15305.6 KDO23720.1 - 6.5e-30 104.1 3.9 6.5e-30 104.1 3.9 1.9 1 1 1 2 2 2 1 Intraflagellar transport protein 43 DUF866 PF05907.13 KDO23721.1 - 1.1e-41 142.3 0.0 1.3e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Nucleoside_tran PF01733.18 KDO23722.1 - 1.1e-19 71.0 18.3 3.2e-17 62.9 18.3 2.2 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KDO23722.1 - 0.00073 18.6 37.6 0.00073 18.6 37.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily bZIP_1 PF00170.21 KDO23723.1 - 1.2 9.3 8.4 2.2 8.5 8.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor Metallophos PF00149.28 KDO23724.1 - 3.1e-15 57.2 0.9 4.4e-15 56.7 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO23724.1 - 0.00085 19.6 0.0 0.0016 18.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 KDO23725.1 - 3.8e-25 87.5 0.1 6.3e-24 83.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KDO23725.1 - 0.00045 19.7 0.9 0.00078 19.0 0.9 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 KDO23725.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KDO23725.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif CSTF2_hinge PF14327.6 KDO23725.1 - 0.0033 17.9 1.0 0.0084 16.5 0.0 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 JmjC PF02373.22 KDO23726.1 - 5.9e-41 139.5 0.2 1.5e-40 138.1 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KDO23726.1 - 5.9e-17 61.3 43.5 6.4e-11 42.0 7.0 4.9 5 0 0 5 5 5 3 PHD-finger JmjN PF02375.17 KDO23726.1 - 9.3e-15 54.3 0.2 2.8e-14 52.8 0.2 1.9 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 KDO23726.1 - 2.5e-14 53.7 0.0 7.5e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PLU-1 PF08429.11 KDO23726.1 - 1.6e-12 47.2 12.4 1.2e-11 44.4 5.2 3.7 2 2 0 2 2 2 1 PLU-1-like protein zf-C5HC2 PF02928.16 KDO23726.1 - 2.7e-09 37.3 14.2 2.7e-09 37.3 14.2 2.9 2 0 0 2 2 2 1 C5HC2 zinc finger AT_hook PF02178.19 KDO23726.1 - 0.00063 19.3 17.0 0.091 12.7 3.9 2.7 2 0 0 2 2 2 2 AT hook motif zf-PHD-like PF15446.6 KDO23726.1 - 0.0031 17.1 23.1 0.078 12.6 5.0 3.9 3 0 0 3 3 3 3 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KDO23726.1 - 0.0068 15.9 28.0 0.049 13.2 3.8 4.6 4 0 0 4 4 4 3 PHD-finger Asp PF00026.23 KDO23727.1 - 1.9e-89 300.2 0.0 2.3e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO23727.1 - 1.3e-10 41.8 0.1 1.8e-05 25.1 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KDO23727.1 - 0.0015 19.1 0.0 0.11 13.1 0.0 2.6 2 1 0 2 2 2 1 Aspartyl protease Voltage_CLC PF00654.20 KDO23728.1 - 3.9e-70 236.9 25.9 3.9e-70 236.9 25.9 1.7 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KDO23728.1 - 0.0034 17.8 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain Guanylate_kin PF00625.21 KDO23729.1 - 1.4e-57 194.3 0.0 1.7e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase RIIa PF02197.17 KDO23729.1 - 8.2e-05 22.2 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RsgA_GTPase PF03193.16 KDO23729.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KDO23729.1 - 0.00045 20.3 0.0 0.00093 19.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO23729.1 - 0.0039 17.7 0.1 0.011 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KDO23729.1 - 0.017 15.6 0.4 0.35 11.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KDO23729.1 - 0.028 14.7 0.0 0.079 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO23729.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KDO23729.1 - 0.05 13.8 0.1 0.33 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO23729.1 - 0.054 13.9 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KDO23729.1 - 0.061 13.2 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 KDO23729.1 - 0.1 13.1 0.1 0.35 11.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KDO23729.1 - 0.11 12.9 0.0 0.41 11.0 0.0 2.0 1 1 1 2 2 2 0 RNA helicase Methyltransf_23 PF13489.6 KDO23730.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain W2 PF02020.18 KDO23731.1 - 6e-12 45.5 1.3 6e-12 45.5 1.3 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NARP1 PF12569.8 KDO23731.1 - 0.024 13.6 12.6 0.033 13.1 12.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4554 PF15091.6 KDO23731.1 - 9.6 5.0 6.1 13 4.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) INTS5_C PF14838.6 KDO23732.1 - 2e-14 53.2 4.2 5.2e-14 51.9 1.4 2.4 3 0 0 3 3 3 2 Integrator complex subunit 5 C-terminus CAP_GLY PF01302.25 KDO23733.1 - 4.3e-19 68.3 0.0 7.7e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DnaJ PF00226.31 KDO23733.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain EF-hand_1 PF00036.32 KDO23734.1 - 2.2e-22 76.9 7.2 3.1e-05 23.2 0.0 5.6 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KDO23734.1 - 3.5e-21 75.4 5.2 7.2e-07 29.6 0.1 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KDO23734.1 - 6.1e-19 66.3 8.5 3.6e-05 23.3 0.0 5.7 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KDO23734.1 - 1.3e-13 50.5 5.8 0.0021 17.8 0.0 5.8 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO23734.1 - 4.9e-13 47.9 4.1 0.00027 20.3 0.1 5.0 5 0 0 5 5 5 4 EF hand WD40 PF00400.32 KDO23734.1 - 5.7e-09 36.5 9.2 0.73 10.8 0.1 7.8 7 0 0 7 7 7 3 WD domain, G-beta repeat EF-hand_9 PF14658.6 KDO23734.1 - 4.9e-06 26.8 0.3 0.00065 20.0 0.1 3.4 4 0 0 4 4 4 1 EF-hand domain KdpD PF02702.17 KDO23734.1 - 0.031 13.8 0.2 0.067 12.7 0.2 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain EF-hand_4 PF12763.7 KDO23734.1 - 0.066 13.2 0.7 13 5.8 0.1 3.3 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand HPS3_N PF14761.6 KDO23734.1 - 0.069 12.7 1.2 0.37 10.3 0.1 2.8 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 E2F_TDP PF02319.20 KDO23735.1 - 5e-22 77.7 0.5 5.8e-12 45.5 0.0 2.6 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.12 KDO23735.1 - 0.0015 18.7 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC DUF4201 PF13870.6 KDO23736.1 - 1.5e-34 119.3 25.2 1.5e-34 119.3 25.2 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 KDO23736.1 - 0.041 12.8 37.8 0.021 13.7 13.6 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 KDO23736.1 - 0.52 9.1 34.2 0.48 9.2 19.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) YabA PF06156.13 KDO23736.1 - 1.2 9.8 34.6 0.24 12.0 5.6 4.6 1 1 3 4 4 4 0 Initiation control protein YabA APG6_N PF17675.1 KDO23736.1 - 1.2 9.6 45.1 4.9 7.7 11.7 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Fez1 PF06818.15 KDO23736.1 - 3 8.2 38.4 7.5 7.0 17.7 3.2 1 1 1 2 2 2 0 Fez1 FGGY_C PF02782.16 KDO23737.1 - 7.3e-20 71.5 0.5 1.7e-19 70.4 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KDO23737.1 - 8.3e-10 38.6 0.0 4.9e-08 32.8 0.0 2.4 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain Pkinase PF00069.25 KDO23738.1 - 1.3e-51 175.5 0.0 5.4e-51 173.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23738.1 - 8.6e-25 87.5 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO23738.1 - 6.8e-07 28.9 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO23738.1 - 1.5e-06 28.4 0.1 0.018 15.0 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO23738.1 - 0.0005 19.7 0.6 0.001 18.7 0.6 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KDO23738.1 - 0.0035 16.7 1.3 0.0038 16.6 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO23738.1 - 0.046 12.5 1.0 0.063 12.0 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase BAR PF03114.18 KDO23739.1 - 2.5e-10 40.4 1.0 3.9e-10 39.8 1.0 1.2 1 0 0 1 1 1 1 BAR domain DUF4745 PF15923.5 KDO23739.1 - 0.015 15.3 1.2 0.037 14.0 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) BAR_3 PF16746.5 KDO23739.1 - 0.047 13.4 1.2 0.069 12.8 1.2 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Spore_YpjB PF09577.10 KDO23739.1 - 0.1 12.4 3.9 2.5 7.9 0.4 2.2 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) PIP5K PF01504.18 KDO23740.1 - 5.2e-71 239.1 0.0 7.1e-70 235.3 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 KDO23740.1 - 6.6e-05 22.1 19.4 0.0019 17.3 19.3 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 KDO23740.1 - 0.00018 20.8 12.8 0.00018 20.8 12.8 2.2 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.9 KDO23740.1 - 0.047 13.1 7.5 0.073 12.4 7.5 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx HSP70 PF00012.20 KDO23741.1 - 3.3e-227 755.4 8.7 3.3e-227 755.4 8.7 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KDO23741.1 - 2.6e-14 52.8 0.5 4.7e-13 48.7 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein TPR_1 PF00515.28 KDO23741.1 - 4.1e-08 32.7 8.8 3.7e-05 23.4 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23741.1 - 5.8e-06 26.0 17.7 0.018 15.1 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO23741.1 - 0.00026 20.9 13.0 0.021 15.0 0.5 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO23741.1 - 0.002 18.7 2.6 0.002 18.7 2.6 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO23741.1 - 0.0052 17.1 2.8 0.82 10.2 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO23741.1 - 0.0061 16.2 10.2 0.26 11.0 1.6 2.9 2 1 0 2 2 2 2 TPR repeat TPR_20 PF14561.6 KDO23741.1 - 0.017 15.5 1.3 0.06 13.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1464 PF07318.12 KDO23741.1 - 0.04 13.1 0.1 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) FtsA PF14450.6 KDO23741.1 - 0.77 10.2 9.9 11 6.5 0.3 4.1 4 2 0 4 4 4 0 Cell division protein FtsA TPR_14 PF13428.6 KDO23741.1 - 1.6 9.7 7.5 61 4.8 0.0 5.0 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO23741.1 - 2 9.0 11.2 3.5 8.2 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1056 PF06341.11 KDO23743.1 - 0.1 12.9 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Exo70 PF03081.15 KDO23744.1 - 2e-40 139.0 0.0 3.8e-40 138.1 0.0 1.5 1 1 0 1 1 1 1 Exo70 exocyst complex subunit COG6 PF06419.11 KDO23744.1 - 5e-06 25.0 3.6 9.8e-05 20.8 0.3 2.4 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 Sec34 PF04136.15 KDO23744.1 - 0.00023 21.0 0.2 0.0006 19.7 0.0 1.7 2 0 0 2 2 2 1 Sec34-like family Anoctamin PF04547.12 KDO23745.1 - 5.6e-63 213.3 14.8 7.7e-63 212.9 14.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_7 PF13499.6 KDO23745.1 - 0.005 17.3 0.3 0.005 17.3 0.3 2.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO23745.1 - 0.022 14.6 2.2 2.3 8.4 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KDO23745.1 - 0.094 12.3 0.1 18 5.2 0.0 2.8 2 0 0 2 2 2 0 EF hand Cation_ATPase_C PF00689.21 KDO23745.1 - 0.5 10.0 11.2 0.44 10.2 8.8 2.3 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus CwfJ_C_1 PF04677.15 KDO23746.1 - 2.4e-31 108.2 0.1 3.9e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KDO23746.1 - 1.5e-11 45.0 0.0 2.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 KDO23746.1 - 0.0096 16.6 0.1 0.03 15.0 0.1 1.9 1 0 0 1 1 1 1 HIT domain Ank_2 PF12796.7 KDO23747.1 - 1.4e-29 102.5 0.2 2.1e-08 34.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23747.1 - 1.1e-25 89.6 7.5 5.3e-08 33.2 0.0 5.9 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23747.1 - 2.7e-24 82.6 0.4 0.00011 22.3 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KDO23747.1 - 2.9e-22 78.4 1.2 1.2e-09 38.3 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO23747.1 - 7e-22 76.8 1.0 0.00015 22.0 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Fic PF02661.18 KDO23747.1 - 4.2e-13 50.0 0.8 9.7e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family DUF3791 PF12668.7 KDO23747.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF4796 PF16044.5 KDO23747.1 - 0.069 12.7 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) Kinesin PF00225.23 KDO23748.1 - 2.8e-96 322.3 0.0 4e-96 321.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO23748.1 - 1.2e-21 77.2 0.0 2.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding IFT57 PF10498.9 KDO23748.1 - 0.011 14.8 7.1 0.019 13.9 7.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_22 PF13401.6 KDO23748.1 - 0.024 14.9 1.5 0.044 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO23748.1 - 0.042 14.2 1.6 0.26 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Csm1_N PF18504.1 KDO23748.1 - 0.16 12.3 12.7 15 6.0 5.8 4.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Herpes_BLRF2 PF05812.12 KDO23748.1 - 0.23 11.6 10.1 2.2 8.5 2.3 3.7 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein Leu_zip PF15294.6 KDO23748.1 - 0.23 10.9 13.7 0.091 12.3 9.9 2.1 1 1 0 2 2 2 0 Leucine zipper bZIP_2 PF07716.15 KDO23748.1 - 1 9.5 27.0 0.36 11.0 1.5 5.4 4 1 1 5 5 5 0 Basic region leucine zipper HALZ PF02183.18 KDO23748.1 - 1.2 9.5 12.5 2.1 8.6 0.2 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper TSC22 PF01166.18 KDO23748.1 - 4.1 7.8 8.5 8 6.9 0.0 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF5094 PF17015.5 KDO23748.1 - 9 6.4 9.7 2.4 8.3 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5094) PI3K_P85_iSH2 PF16454.5 KDO23748.1 - 10 5.7 18.3 7.9 6.1 7.0 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GIDA PF01134.22 KDO23749.1 - 7.7e-154 512.5 0.0 1e-153 512.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KDO23749.1 - 7.8e-65 219.0 0.0 1.1e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KDO23749.1 - 1.5e-07 31.0 2.3 1e-06 28.2 2.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO23749.1 - 1e-06 28.4 3.5 1.5e-06 27.9 3.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO23749.1 - 2.6e-06 26.8 4.2 8.7e-06 25.1 2.5 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KDO23749.1 - 0.00023 20.5 0.2 0.00055 19.3 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KDO23749.1 - 0.00095 19.7 0.2 0.0025 18.3 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO23749.1 - 0.0014 17.4 5.7 0.0072 15.1 0.7 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 KDO23749.1 - 0.0029 16.9 0.5 0.034 13.4 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO23749.1 - 0.0045 16.6 6.4 0.68 9.5 3.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO23749.1 - 0.0071 15.4 1.6 0.022 13.8 1.6 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KDO23749.1 - 0.03 13.6 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KDO23749.1 - 0.17 12.1 1.3 0.4 10.9 1.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KDO23749.1 - 0.28 10.0 1.1 1.3 7.8 0.8 1.9 2 0 0 2 2 2 0 Tryptophan halogenase PI3K_P85_iSH2 PF16454.5 KDO23750.1 - 0.2 11.3 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Anoctamin PF04547.12 KDO23751.1 - 1.6e-37 129.4 24.6 6.1e-36 124.2 24.6 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel EF-hand_6 PF13405.6 KDO23751.1 - 0.0037 17.1 0.1 2.8 8.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KDO23751.1 - 0.0042 17.5 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair Comm PF15957.5 KDO23751.1 - 4.6 7.6 5.3 9.3 6.6 0.4 3.4 3 0 0 3 3 3 0 Commissureless RRM_1 PF00076.22 KDO23752.1 - 4.4e-05 23.2 0.5 0.00028 20.6 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhetRS_B1 PF18262.1 KDO23752.1 - 0.027 14.7 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Retrotran_gag_2 PF14223.6 KDO23752.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Glyco_hydro_46 PF01374.18 KDO23752.1 - 0.26 10.9 0.7 0.41 10.2 0.7 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 Ion_trans_2 PF07885.16 KDO23753.1 - 6e-12 45.4 4.7 6e-12 45.4 4.7 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KDO23753.1 - 0.038 13.2 14.7 0.081 12.1 14.7 1.6 1 1 0 1 1 1 0 Ion transport protein SK_channel PF03530.14 KDO23753.1 - 0.35 10.9 4.6 0.082 12.9 0.8 1.9 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Patatin PF01734.22 KDO23754.1 - 3.3e-09 37.2 4.3 0.0014 18.9 0.5 2.6 2 1 0 3 3 3 2 Patatin-like phospholipase TPR_11 PF13414.6 KDO23755.1 - 1.2e-11 44.1 0.1 4.9e-08 32.5 0.0 3.9 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 KDO23755.1 - 8.2e-11 42.4 26.6 0.002 18.7 0.3 6.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23755.1 - 7.3e-10 38.2 6.4 6.3e-06 25.9 0.2 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23755.1 - 1.7e-09 37.7 32.7 0.00012 22.6 1.1 7.8 3 1 6 9 9 7 3 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 KDO23755.1 - 1.9e-08 33.2 0.0 7.1e-05 21.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KDO23755.1 - 5.2e-08 32.4 0.6 1.2e-05 24.9 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO23755.1 - 2.9e-07 30.4 0.7 0.023 15.1 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO23755.1 - 6e-07 29.9 18.0 1.7e-05 25.2 0.5 4.5 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KDO23755.1 - 4.3e-06 26.2 3.2 4.3e-06 26.2 3.2 1.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO23755.1 - 1.4e-05 24.7 14.1 0.028 13.8 0.6 3.6 1 1 2 3 3 3 3 MalT-like TPR region TPR_6 PF13174.6 KDO23755.1 - 0.00029 21.3 2.3 12 6.8 0.1 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO23755.1 - 0.0008 19.6 0.1 0.0024 18.0 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 KDO23755.1 - 0.0019 18.0 0.1 0.007 16.1 0.1 1.9 2 0 0 2 2 2 1 Outer membrane lipoprotein TPR_8 PF13181.6 KDO23755.1 - 0.0037 17.4 0.0 12 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat fn3 PF00041.21 KDO23755.1 - 0.011 16.0 0.1 0.025 14.9 0.1 1.5 1 0 0 1 1 1 0 Fibronectin type III domain TPR_12 PF13424.6 KDO23755.1 - 0.014 15.7 15.5 0.16 12.3 1.1 5.2 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO23755.1 - 0.015 15.2 6.6 1.7 8.7 0.4 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Uroplakin_II PF07353.12 KDO23755.1 - 0.051 13.1 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Uroplakin II NARP1 PF12569.8 KDO23755.1 - 0.14 11.0 1.7 5.2 5.9 0.0 2.8 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Pur_ac_phosph_N PF16656.5 KDO23755.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain TPR_20 PF14561.6 KDO23755.1 - 1.9 8.9 11.9 6.3 7.2 0.7 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat NAD_binding_2 PF03446.15 KDO23756.1 - 1.8e-50 171.2 1.0 3.4e-50 170.3 1.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KDO23756.1 - 5.8e-34 117.0 2.5 5.8e-34 117.0 2.5 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KDO23756.1 - 2.4e-09 37.7 0.0 5.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KDO23756.1 - 4.4e-06 26.8 0.2 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KDO23756.1 - 5e-06 26.0 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KDO23756.1 - 9.3e-05 22.7 0.0 0.00044 20.5 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KDO23756.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KDO23756.1 - 0.0014 19.0 0.0 0.0099 16.3 0.0 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 KDO23756.1 - 0.024 14.3 0.7 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KDO23756.1 - 0.036 14.3 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KDO23756.1 - 0.06 12.8 0.0 0.29 10.6 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DIOX_N PF14226.6 KDO23757.1 - 3.6e-10 40.6 0.0 6.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO23757.1 - 2.4e-06 27.9 0.0 4.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SEN1_N PF12726.7 KDO23757.1 - 0.071 11.3 0.0 0.098 10.9 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal ASCH PF04266.14 KDO23757.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 ASCH domain NAD_binding_11 PF14833.6 KDO23758.1 - 1.7e-35 121.9 1.3 2e-35 121.7 1.3 1.1 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase INTS2 PF14750.6 KDO23759.1 - 3.3e-07 28.3 0.6 4.1e-07 28.0 0.6 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 INTS2 PF14750.6 KDO23760.1 - 9.1e-14 50.0 0.2 2e-13 48.9 0.2 1.6 1 1 0 1 1 1 1 Integrator complex subunit 2 EAF PF09816.9 KDO23761.1 - 2.6e-16 59.8 0.0 3.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor 5_nucleotid_C PF02872.18 KDO23762.1 - 4.8e-21 75.6 0.0 9.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KDO23762.1 - 1.4e-06 29.0 0.0 2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1837 PF08878.11 KDO23765.1 - 0.15 11.8 0.1 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) Pro_CA PF00484.19 KDO23765.1 - 0.15 12.3 1.3 0.32 11.3 0.8 1.9 1 1 0 1 1 1 0 Carbonic anhydrase AAA_22 PF13401.6 KDO23766.1 - 6.5e-05 23.2 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KDO23766.1 - 0.00037 20.0 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3781 PF12636.7 KDO23766.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) AAA_14 PF13173.6 KDO23766.1 - 0.034 14.2 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KDO23766.1 - 0.041 13.9 0.0 7 6.7 0.0 2.3 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KDO23766.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KDO23766.1 - 0.075 13.1 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 KDO23766.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 5_nucleotid_C PF02872.18 KDO23768.1 - 5.4e-24 85.2 0.0 6.6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Acyl_transf_1 PF00698.21 KDO23769.1 - 1e-13 51.5 0.7 1.1e-13 51.3 0.7 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KDO23769.1 - 0.011 15.5 0.2 0.059 13.1 0.2 1.9 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis CobT_C PF11775.8 KDO23769.1 - 0.047 13.3 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Histone PF00125.24 KDO23770.1 - 8.1e-53 178.3 1.3 9e-53 178.1 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KDO23770.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KDO23770.1 - 0.00028 21.5 0.3 0.00033 21.3 0.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO23770.1 - 0.00048 20.2 0.0 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KDO23770.1 - 0.0028 17.9 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO23770.1 - 0.12 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RasGAP PF00616.19 KDO23771.1 - 1.2e-11 44.7 0.0 3.4e-09 36.7 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase START PF01852.19 KDO23771.1 - 0.0025 17.3 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 START domain Rad51 PF08423.11 KDO23773.1 - 2e-36 125.6 0.0 2.4e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KDO23773.1 - 1.3e-10 41.0 0.1 1.2e-07 31.4 0.0 2.3 2 1 0 2 2 2 2 KaiC RecA PF00154.21 KDO23773.1 - 2.6e-08 33.7 1.1 9.6e-08 31.8 1.1 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KDO23773.1 - 4.2e-07 29.7 1.4 8.3e-06 25.5 1.4 2.1 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KDO23773.1 - 0.00012 21.5 0.1 0.12 11.7 0.0 2.6 1 1 2 3 3 3 2 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KDO23773.1 - 0.00018 21.8 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO23773.1 - 0.054 13.6 0.3 0.17 12.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KDO23773.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KDO23773.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KDO23773.1 - 0.14 11.8 0.1 0.85 9.2 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KDO23773.1 - 0.15 12.6 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.11 KDO23774.1 - 1.7 6.8 6.7 2.1 6.5 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EF-hand_5 PF13202.6 KDO23775.1 - 1.4e-05 24.4 0.1 2.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KDO23775.1 - 5.8e-05 22.4 0.0 0.00017 20.9 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO23775.1 - 0.00033 20.4 0.1 0.0013 18.5 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KDO23775.1 - 0.0039 17.6 0.1 0.013 15.9 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO23775.1 - 0.0095 15.8 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair DAO PF01266.24 KDO23775.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase ATG16 PF08614.11 KDO23776.1 - 0.077 13.2 57.0 0.25 11.5 10.4 3.9 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KDO23776.1 - 0.22 12.2 32.7 0.65 10.7 6.5 5.0 1 1 4 5 5 5 0 Initiation control protein YabA MRG PF05712.13 KDO23777.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 MRG MtN3_slv PF03083.16 KDO23779.1 - 2.3e-23 82.0 10.6 6.1e-16 58.2 0.2 2.1 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MtN3_slv PF03083.16 KDO23780.1 - 2.7e-24 85.0 14.4 8e-16 57.9 0.8 2.8 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange TPH PF13868.6 KDO23782.1 - 0.12 10.9 9.3 0.17 10.4 9.3 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain ING PF12998.7 KDO23782.1 - 4.2 8.0 6.5 2.8 8.6 4.5 1.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Sulf_transp PF04143.14 KDO23785.1 - 4.5e-33 115.1 30.4 7.4e-33 114.4 30.4 1.3 1 1 0 1 1 1 1 Sulphur transport PDZ PF00595.24 KDO23786.1 - 5.2e-11 42.7 0.0 0.0003 21.1 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KDO23786.1 - 0.0038 17.0 0.0 13 5.7 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KDO23786.1 - 0.094 13.1 0.0 14 6.1 0.0 2.9 3 0 0 3 3 3 0 PDZ domain TFIIA PF03153.13 KDO23786.1 - 0.18 11.8 34.7 0.28 11.2 34.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sulf_transp PF04143.14 KDO23787.1 - 9.7e-27 94.3 32.4 9.7e-27 94.3 32.4 2.1 1 1 1 2 2 2 1 Sulphur transport NADH5_C PF06455.11 KDO23787.1 - 8.3 6.0 15.3 0.067 12.8 1.4 3.0 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus START PF01852.19 KDO23788.1 - 7.7e-07 28.7 0.1 1.4e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 START domain zf-RING_5 PF14634.6 KDO23788.1 - 3.1 7.8 13.8 7.6 6.6 13.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain MCM_bind PF09739.9 KDO23789.1 - 0.12 10.8 0.2 0.45 8.9 0.1 1.7 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor ADH_zinc_N PF00107.26 KDO23790.1 - 4.5e-27 94.6 0.4 7.4e-27 93.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO23790.1 - 7.1e-26 91.8 0.1 2.7e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO23790.1 - 1.7e-08 34.3 0.0 3.1e-07 30.3 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KDO23790.1 - 0.13 11.7 0.3 0.26 10.7 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase IPP-2 PF04979.14 KDO23791.1 - 3.6e-22 79.5 8.4 5.1e-22 79.0 8.4 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) SHIPPO-rpt PF07004.12 KDO23792.1 - 1.3e-20 73.3 24.3 0.00059 20.6 1.2 6.7 6 1 0 6 6 6 6 Sperm-tail PG-rich repeat Lebercilin PF15619.6 KDO23793.1 - 0.0022 17.7 3.7 0.0024 17.5 3.7 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GvpK PF05121.12 KDO23793.1 - 0.015 15.3 0.4 0.028 14.5 0.3 1.5 1 1 0 1 1 1 0 Gas vesicle protein K ATG16 PF08614.11 KDO23793.1 - 0.018 15.3 7.2 0.18 12.0 0.3 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 KDO23793.1 - 0.018 15.1 0.9 0.023 14.8 0.9 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein IPPT PF01715.17 KDO23793.1 - 0.023 14.5 0.8 0.026 14.3 0.8 1.2 1 0 0 1 1 1 0 IPP transferase OmpH PF03938.14 KDO23793.1 - 0.028 14.7 2.1 0.032 14.5 2.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3053 PF11254.8 KDO23793.1 - 0.046 13.3 0.7 0.048 13.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Med12 PF09497.10 KDO23794.1 - 0.0037 17.5 0.2 0.0042 17.3 0.2 1.2 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med26 PF08711.11 KDO23794.1 - 0.026 14.5 0.3 0.046 13.7 0.3 1.6 1 1 0 1 1 1 0 TFIIS helical bundle-like domain T3SS_needle_E PF08988.10 KDO23794.1 - 0.048 13.8 0.7 0.069 13.3 0.7 1.3 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Apt1 PF10351.9 KDO23794.1 - 0.065 12.1 0.5 0.069 12.0 0.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PHD PF00628.29 KDO23795.1 - 2e-07 30.8 7.2 3.8e-07 29.9 7.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KDO23795.1 - 0.00023 21.3 7.3 0.0003 21.0 6.5 1.7 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KDO23795.1 - 0.00028 21.0 5.6 0.00033 20.8 4.6 1.8 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD_2 PF13831.6 KDO23795.1 - 0.0015 18.1 2.6 0.0029 17.1 2.6 1.5 1 0 0 1 1 1 1 PHD-finger PEHE PF15275.6 KDO23795.1 - 0.0018 18.9 1.1 0.0023 18.5 1.1 1.2 1 0 0 1 1 1 1 PEHE domain C1_2 PF03107.16 KDO23795.1 - 0.0073 16.6 4.1 0.02 15.2 1.7 2.2 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 KDO23795.1 - 0.012 15.5 3.5 0.012 15.5 3.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) V_ATPase_I PF01496.19 KDO23795.1 - 0.082 10.8 1.0 0.08 10.9 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_2 PF13639.6 KDO23795.1 - 0.1 12.9 6.7 0.2 12.0 6.7 1.5 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 KDO23795.1 - 0.16 12.1 3.6 0.47 10.6 3.6 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger zf-PHD-like PF15446.6 KDO23795.1 - 0.19 11.3 8.6 0.038 13.6 3.9 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Spc7 PF08317.11 KDO23795.1 - 0.2 10.5 8.6 0.24 10.2 8.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cytochrome_C7 PF14522.6 KDO23795.1 - 2.2 8.3 9.8 0.45 10.6 4.9 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 KDO23795.1 - 2.6 8.2 11.2 27 5.0 0.2 3.5 2 1 1 3 3 3 0 Zinc ribbon domain zf-RING_9 PF13901.6 KDO23795.1 - 3.2 7.7 16.0 0.71 9.8 8.6 2.2 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon zf-C4H2 PF10146.9 KDO23795.1 - 8.5 6.6 15.1 27 5.0 15.1 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein zf-TFIIB PF13453.6 KDO23795.1 - 9 5.7 8.6 21 4.5 0.2 2.8 2 1 1 3 3 3 0 Transcription factor zinc-finger DUF2613 PF11021.8 KDO23797.1 - 3.9 7.6 8.6 1.2 9.2 4.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2315 PF10231.9 KDO23798.1 - 0.25 11.4 8.3 0.45 10.6 7.9 1.6 1 1 1 2 2 2 0 Apoptogenic protein 1 DUF1168 PF06658.12 KDO23798.1 - 5.6 6.8 18.2 8.7 6.2 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4670 PF15709.5 KDO23798.1 - 6.9 5.9 22.2 8.3 5.6 22.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Serinc PF03348.15 KDO23799.1 - 5.6e-57 193.6 1.8 6.4e-57 193.4 1.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) UFC1 PF08694.11 KDO23800.1 - 2.2e-64 215.7 0.1 2.5e-64 215.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 KDO23800.1 - 0.0037 16.9 0.1 0.006 16.2 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Nic96 PF04097.14 KDO23801.1 - 4.1e-73 246.9 1.5 2e-72 244.6 1.5 2.0 1 1 0 1 1 1 1 Nup93/Nic96 Frigida PF07899.11 KDO23801.1 - 0.012 14.9 0.1 0.88 8.8 0.0 2.5 2 0 0 2 2 2 0 Frigida-like protein TetR_C_18 PF17923.1 KDO23801.1 - 0.071 13.6 0.4 5.4 7.6 0.0 3.6 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Aa_trans PF01490.18 KDO23802.1 - 1.2e-37 129.6 31.5 1.6e-37 129.3 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ras PF00071.22 KDO23803.1 - 1.9e-30 105.6 0.0 2.3e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO23803.1 - 9.3e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23803.1 - 1.8e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KDO23803.1 - 0.0015 18.4 0.0 0.72 9.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO23803.1 - 0.017 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KDO23803.1 - 0.072 13.2 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO23803.1 - 0.073 12.4 0.0 0.32 10.3 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KDO23803.1 - 0.092 12.3 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Ras PF00071.22 KDO23804.1 - 4.7e-81 270.1 0.0 2.6e-40 137.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KDO23804.1 - 1.6e-53 180.0 0.0 5.9e-26 91.0 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO23804.1 - 9.4e-17 61.0 0.0 3.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO23804.1 - 3.3e-09 36.8 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO23804.1 - 3.4e-09 36.4 0.0 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO23804.1 - 1.5e-07 31.5 0.5 0.0061 16.5 0.0 3.5 3 1 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KDO23804.1 - 2.7e-06 27.9 0.0 0.072 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KDO23804.1 - 9.9e-06 25.2 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 KDO23804.1 - 1.1e-05 25.1 0.2 0.045 13.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MCM PF00493.23 KDO23804.1 - 3e-05 23.2 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain ArgoMid PF16487.5 KDO23804.1 - 3.1e-05 24.1 0.4 0.1 12.9 0.1 2.4 2 0 0 2 2 2 2 Mid domain of argonaute RNA_helicase PF00910.22 KDO23804.1 - 5.3e-05 23.6 0.5 0.092 13.1 0.1 3.5 2 2 0 2 2 2 1 RNA helicase Septin PF00735.18 KDO23804.1 - 9.6e-05 21.8 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_24 PF13479.6 KDO23804.1 - 0.00011 22.0 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KDO23804.1 - 0.00013 22.5 0.0 0.27 11.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter GTP_EFTU PF00009.27 KDO23804.1 - 0.00037 20.1 0.0 0.11 12.0 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KDO23804.1 - 0.00065 20.0 0.1 0.46 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KDO23804.1 - 0.00093 18.5 1.2 2.7 7.0 0.1 3.9 3 2 1 4 4 4 1 G-protein alpha subunit AAA_33 PF13671.6 KDO23804.1 - 0.0014 18.8 0.2 0.26 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KDO23804.1 - 0.0024 17.3 0.1 2.6 7.4 0.0 3.0 4 0 0 4 4 3 1 Bacterial TniB protein NACHT PF05729.12 KDO23804.1 - 0.003 17.5 0.9 0.26 11.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 KDO23804.1 - 0.0047 16.1 0.0 0.6 9.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KDO23804.1 - 0.011 15.8 0.4 5.5 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KDO23804.1 - 0.046 12.9 0.1 5.3 6.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DAP3 PF10236.9 KDO23804.1 - 0.077 12.2 0.1 3 6.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Hpr_kinase_C PF07475.12 KDO23804.1 - 0.081 12.4 0.2 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain OKR_DC_1_N PF03709.15 KDO23804.1 - 0.088 13.1 0.1 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_25 PF13481.6 KDO23804.1 - 0.1 12.1 0.1 14 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KDO23804.1 - 0.11 12.2 0.0 6.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Ploopntkinase3 PF18751.1 KDO23804.1 - 0.14 12.1 0.0 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 KDO23804.1 - 0.16 12.0 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KDO23804.1 - 0.16 11.9 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 NTPase zf-C3HC4 PF00097.25 KDO23805.1 - 7.9e-09 35.3 3.0 1.5e-08 34.4 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO23805.1 - 1.5e-08 34.4 5.4 3.7e-08 33.1 5.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO23805.1 - 8.2e-08 32.5 5.5 1.9e-07 31.3 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO23805.1 - 3.5e-07 30.1 1.8 3.5e-07 30.1 1.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO23805.1 - 6.5e-07 29.2 3.1 1.2e-06 28.4 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO23805.1 - 9.6e-06 25.6 0.9 2.1e-05 24.5 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO23805.1 - 2.4e-05 24.1 4.4 5.2e-05 23.0 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO23805.1 - 0.00012 22.3 1.9 0.00029 21.1 1.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KDO23805.1 - 0.00013 22.1 4.7 0.00023 21.2 4.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KDO23805.1 - 0.003 17.3 0.9 0.0061 16.4 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KDO23805.1 - 0.006 16.4 5.2 0.2 11.5 6.0 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-CRD PF17979.1 KDO23805.1 - 0.02 15.0 0.4 0.046 13.8 0.4 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions PWI PF01480.17 KDO23805.1 - 0.032 14.5 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 PWI domain Rad50_zn_hook PF04423.14 KDO23805.1 - 0.11 12.4 0.2 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KDO23805.1 - 0.62 9.9 6.3 3.6 7.5 6.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Tweety PF04906.13 KDO23806.1 - 0.00054 18.8 21.0 0.015 14.0 3.7 3.2 3 0 0 3 3 3 2 Tweety Baculo_PEP_C PF04513.12 KDO23806.1 - 0.0066 16.5 3.9 0.0066 16.5 3.9 3.6 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus PuR_N PF09182.10 KDO23806.1 - 0.12 12.4 0.3 0.38 10.7 0.3 1.9 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Prominin PF05478.11 KDO23806.1 - 0.22 9.4 28.8 0.069 11.1 4.3 3.3 3 1 0 3 3 3 0 Prominin Prominin PF05478.11 KDO23807.1 - 0.00035 18.7 13.3 0.0023 16.0 0.6 3.2 3 0 0 3 3 3 3 Prominin DUF2207 PF09972.9 KDO23807.1 - 0.7 8.6 8.2 0.74 8.5 2.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 KDO23807.1 - 1.7 8.3 17.3 0.53 9.9 8.3 3.0 3 0 0 3 3 3 0 Tetraspanin family DUF1282 PF06930.12 KDO23807.1 - 3.5 7.4 17.7 0.091 12.5 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) Peptidase_C74 PF12387.8 KDO23808.1 - 0.011 15.2 0.0 0.058 12.9 0.0 2.0 2 0 0 2 2 2 0 Pestivirus NS2 peptidase Ank_5 PF13857.6 KDO23809.1 - 2.5e-31 107.3 2.3 2.3e-13 50.1 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23809.1 - 1.9e-30 105.2 2.8 2.7e-09 37.5 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23809.1 - 1.9e-23 82.5 1.9 8.9e-06 26.2 0.1 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO23809.1 - 8.9e-20 70.2 4.9 1.3e-06 28.5 0.3 6.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 KDO23809.1 - 8.3e-17 59.6 1.0 0.0038 17.6 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat TFIIF_alpha PF05793.12 KDO23809.1 - 0.17 10.5 16.1 0.26 9.8 16.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GRDP-like PF07173.12 KDO23810.1 - 1.2e-15 58.4 0.1 2.7e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like PH PF00169.29 KDO23810.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 PH domain JAB PF01398.21 KDO23811.1 - 3.7e-32 110.8 0.6 5.7e-32 110.2 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KDO23811.1 - 3.4e-14 53.2 0.5 6e-14 52.4 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KDO23811.1 - 5e-06 26.3 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KDO23811.1 - 0.0018 18.4 0.1 0.0033 17.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Baculo_ME53 PF06061.11 KDO23811.1 - 0.052 12.8 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 HPP PF04982.13 KDO23812.1 - 3.3e-45 153.2 11.3 8.5e-45 151.9 10.3 1.8 2 0 0 2 2 2 1 HPP family Enkurin PF13864.6 KDO23813.1 - 5.3e-26 90.9 5.4 9e-26 90.2 5.4 1.3 1 0 0 1 1 1 1 Calmodulin-binding HPP PF04982.13 KDO23814.1 - 3.3e-42 143.5 9.1 4e-42 143.3 6.2 2.0 2 0 0 2 2 2 1 HPP family DEAD PF00270.29 KDO23815.1 - 1.8e-34 119.0 0.0 3.3e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO23815.1 - 2.2e-24 85.9 0.1 5.7e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KDO23815.1 - 0.0027 17.1 0.1 0.0059 16.0 0.1 1.6 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PAN_1 PF00024.26 KDO23816.1 - 5.9e-12 45.4 0.2 2.6e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 KDO23816.1 - 5.2e-09 35.9 11.1 3.8e-08 33.1 1.6 3.4 3 1 0 3 3 3 2 PAN domain PIG-L PF02585.17 KDO23816.1 - 5.5e-05 23.8 0.1 0.00015 22.4 0.1 1.8 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_2 PF08276.11 KDO23816.1 - 0.00035 20.6 4.5 0.017 15.2 0.4 2.6 2 0 0 2 2 2 2 PAN-like domain Myb_DNA-binding PF00249.31 KDO23817.1 - 6.5e-10 39.0 0.7 8.6e-10 38.7 0.1 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO23817.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KDO23817.1 - 0.074 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2046 PF09755.9 KDO23818.1 - 9.5e-07 28.3 32.0 5.8e-05 22.5 5.0 3.3 3 0 0 3 3 3 2 Uncharacterized conserved protein H4 (DUF2046) RILP PF11461.8 KDO23818.1 - 7.8 6.8 8.5 16 5.8 0.9 3.7 3 0 0 3 3 3 0 Rab interacting lysosomal protein p450 PF00067.22 KDO23819.1 - 2.7e-39 135.2 0.0 2.2e-38 132.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 MatE PF01554.18 KDO23820.1 - 2.4e-45 154.1 33.4 5e-24 84.8 9.7 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO23820.1 - 0.00049 20.2 4.0 0.00049 20.2 4.0 4.6 3 2 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KDO23821.1 - 4.5e-46 156.4 28.9 2.6e-27 95.5 11.0 2.8 2 1 0 2 2 2 2 MatE Myb_DNA-binding PF00249.31 KDO23822.1 - 1.4e-16 60.4 5.5 3.8e-05 23.8 0.0 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO23822.1 - 1.5e-15 57.2 1.6 8.4e-08 32.4 0.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO23822.1 - 0.0021 18.4 4.7 0.062 13.7 0.7 3.6 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KDO23822.1 - 0.0057 16.7 0.1 0.96 9.6 0.2 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain UEV PF05743.13 KDO23823.1 - 4.3e-36 123.4 0.1 9.2e-36 122.4 0.1 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KDO23823.1 - 4.7e-23 80.9 1.0 1.1e-22 79.7 1.0 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KDO23823.1 - 6e-06 26.0 1.2 1.1e-05 25.0 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Syntaxin_2 PF14523.6 KDO23823.1 - 0.24 11.8 4.7 5.4 7.4 0.0 3.6 3 1 1 4 4 4 0 Syntaxin-like protein DUF745 PF05335.13 KDO23823.1 - 0.3 10.8 11.0 0.088 12.5 7.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) K-box PF01486.17 KDO23823.1 - 0.66 10.2 8.1 1 9.6 7.2 1.8 2 0 0 2 2 2 0 K-box region BET PF17035.5 KDO23824.1 - 0.086 13.0 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation DSPn PF14671.6 KDO23825.1 - 2e-40 138.5 0.1 2.6e-39 134.9 0.1 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KDO23825.1 - 2.5e-16 59.7 0.0 1.2e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO23825.1 - 2.2e-06 27.4 0.0 8.4e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO23825.1 - 0.0023 18.1 0.0 0.0054 16.9 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KDO23825.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family SMC_N PF02463.19 KDO23826.1 - 1.8e-20 73.4 0.0 2.1e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO23826.1 - 4.2e-16 60.1 0.0 4.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KDO23826.1 - 1.7e-09 37.9 0.0 1.7e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO23826.1 - 4.4e-08 32.8 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO23826.1 - 1.7e-06 28.0 0.0 2.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 KDO23826.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KDO23826.1 - 0.0049 17.4 0.0 0.0058 17.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 KDO23826.1 - 0.027 14.9 0.0 0.039 14.4 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KDO23826.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KDO23826.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KDO23826.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytochrom_B558a PF05038.13 KDO23826.1 - 0.098 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit AAA_16 PF13191.6 KDO23826.1 - 0.14 12.6 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KDO23826.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ring_hydroxyl_A PF00848.19 KDO23827.1 - 4.1e-38 131.5 0.1 7.2e-38 130.7 0.1 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KDO23827.1 - 1.2e-14 54.0 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CCT PF06203.14 KDO23828.1 - 4e-18 65.2 9.4 6.8e-18 64.4 9.4 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 KDO23828.1 - 0.0023 17.7 0.2 0.0057 16.5 0.2 1.7 1 0 0 1 1 1 1 Divergent CCT motif IMUP PF15761.5 KDO23828.1 - 0.76 10.5 3.1 9.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein PNGaseA PF12222.8 KDO23830.1 - 1.6e-87 294.2 2.8 2.1e-87 293.8 2.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A TMEM164 PF14808.6 KDO23831.1 - 3.1e-20 72.6 10.4 4.5e-20 72.1 10.4 1.2 1 0 0 1 1 1 1 TMEM164 family Ank_5 PF13857.6 KDO23832.1 - 4e-11 42.9 4.6 7.7e-05 22.9 0.9 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO23832.1 - 6.3e-10 39.0 7.1 8.4e-06 26.0 0.2 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO23832.1 - 6.9e-10 39.4 4.2 0.00029 21.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO23832.1 - 2.8e-07 30.3 1.1 0.0018 18.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KDO23832.1 - 1.9e-06 28.3 2.1 0.00052 20.5 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF2431 PF10354.9 KDO23834.1 - 1.4e-06 28.6 0.0 2.8e-05 24.5 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) DTHCT PF08070.11 KDO23834.1 - 2 9.2 16.7 5.9 7.7 16.3 1.9 1 1 0 1 1 1 0 DTHCT (NUC029) region FYVE PF01363.21 KDO23835.1 - 3e-11 43.3 12.4 7.1e-11 42.1 12.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO23835.1 - 0.00043 20.5 5.3 0.00082 19.6 5.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO23836.1 - 3e-14 52.9 8.1 5.8e-14 52.0 8.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO23836.1 - 0.00048 20.8 0.0 0.0019 18.9 0.0 2.1 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO23836.1 - 0.0016 18.6 2.3 0.0032 17.7 2.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_2 PF13639.6 KDO23836.1 - 0.22 11.9 9.4 0.53 10.7 9.4 1.7 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 KDO23836.1 - 0.73 10.0 4.0 1.6 8.9 4.0 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Pkinase PF00069.25 KDO23837.1 - 7.3e-39 133.7 0.0 1.3e-38 132.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23837.1 - 1.7e-17 63.6 0.0 2.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO23837.1 - 0.006 16.0 0.2 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO23837.1 - 0.0087 16.0 0.5 0.043 13.7 0.3 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3682 PF12446.8 KDO23837.1 - 0.027 14.9 2.4 0.052 14.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) VEGF_C PF14554.6 KDO23837.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain SnoaL_2 PF12680.7 KDO23838.1 - 2e-09 38.0 0.0 2.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KDO23838.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 1.2 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KDO23838.1 - 0.0027 18.1 0.0 0.0036 17.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 KDO23838.1 - 0.068 13.3 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.12 KDO23838.1 - 0.15 11.9 0.0 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase ERCC3_RAD25_C PF16203.5 KDO23839.1 - 1.8e-108 361.5 0.1 3.1e-108 360.7 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KDO23839.1 - 4.8e-35 120.5 0.0 1e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO23839.1 - 4.1e-13 49.7 0.0 1.1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO23839.1 - 7e-10 39.2 0.0 2e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KDO23839.1 - 2.6e-06 26.4 0.0 4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf_C2H2_6 PF18450.1 KDO23839.1 - 0.068 12.9 0.4 0.17 11.6 0.4 1.6 1 0 0 1 1 1 0 Zinc Finger domain RNR_N PF08343.10 KDO23839.1 - 0.13 12.3 1.6 0.48 10.5 0.2 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Cupin_8 PF13621.6 KDO23841.1 - 1.6e-73 247.6 0.0 1.9e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO23841.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein DUF2661 PF10860.8 KDO23841.1 - 0.014 15.5 0.7 0.03 14.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) Pep_deformylase PF01327.21 KDO23842.1 - 1.1e-42 145.3 0.0 1.4e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase ClpS PF02617.17 KDO23842.1 - 0.41 10.5 1.5 1.4 8.7 0.3 2.1 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS RhaA PF06134.11 KDO23843.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) AA_permease_2 PF13520.6 KDO23845.1 - 6.5e-37 127.4 20.3 6.5e-37 127.4 20.3 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KDO23845.1 - 9e-22 77.3 27.2 9e-22 77.3 27.2 2.8 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KDO23845.1 - 2.7e-07 30.6 8.3 2.7e-07 30.6 8.3 2.4 2 0 0 2 2 2 1 C-terminus of AA_permease Sigma_reg_N PF13800.6 KDO23845.1 - 0.13 12.5 1.6 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal AA_permease_2 PF13520.6 KDO23846.1 - 7.4e-34 117.3 34.9 9.6e-33 113.6 34.8 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO23846.1 - 3.3e-29 101.8 27.7 3.3e-29 101.8 27.7 2.5 2 1 1 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 KDO23846.1 - 2.3e-11 43.6 11.8 2.3e-11 43.6 11.8 3.7 5 0 0 5 5 5 1 C-terminus of AA_permease Ion_trans PF00520.31 KDO23847.1 - 2.3e-22 79.5 9.8 3.1e-22 79.0 9.8 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO23847.1 - 8.1e-09 35.3 6.4 2e-08 34.1 5.6 2.0 1 1 0 1 1 1 1 Ion channel IBR PF01485.21 KDO23848.1 - 1.3e-22 79.8 24.0 6.1e-16 58.4 2.5 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KDO23848.1 - 9.9e-06 25.3 4.8 9.9e-06 25.3 4.8 5.0 3 1 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO23848.1 - 6.2e-05 22.8 6.5 6.2e-05 22.8 6.5 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO23848.1 - 0.0016 18.2 7.4 0.0016 18.2 7.4 4.7 2 1 2 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Glycophorin_A PF01102.18 KDO23850.1 - 0.0015 18.7 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Glycophorin A Saf_2TM PF18303.1 KDO23850.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain MARVEL PF01284.23 KDO23850.1 - 0.012 15.7 0.2 0.014 15.5 0.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain RIFIN PF02009.16 KDO23850.1 - 0.024 14.5 0.0 0.027 14.4 0.0 1.0 1 0 0 1 1 1 0 Rifin DUF485 PF04341.12 KDO23850.1 - 0.025 14.5 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Vpu PF00558.19 KDO23850.1 - 0.034 13.9 0.4 0.054 13.3 0.4 1.3 1 0 0 1 1 1 0 Vpu protein COX6C PF02937.15 KDO23850.1 - 0.087 13.0 0.5 0.14 12.3 0.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Orf78 PF06024.12 KDO23850.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF3290 PF11694.8 KDO23850.1 - 0.11 12.4 1.0 0.16 12.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) CDC50 PF03381.15 KDO23850.1 - 0.21 11.1 0.2 0.27 10.7 0.2 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Ank_4 PF13637.6 KDO23851.1 - 8.4e-23 80.4 5.8 1.1e-11 45.0 0.4 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23851.1 - 1.1e-15 56.1 0.4 4.9e-06 26.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO23851.1 - 2.6e-15 56.1 2.5 3.2e-07 30.5 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO23851.1 - 6e-15 55.6 0.3 9.5e-14 51.8 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO23851.1 - 3.1e-14 52.8 0.8 4.9e-08 33.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CK2S PF15011.6 KDO23852.1 - 4e-11 43.1 0.0 7e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Casein Kinase 2 substrate Microvir_H PF04687.12 KDO23852.1 - 0.0037 16.7 0.1 0.37 10.1 0.0 2.1 2 0 0 2 2 2 2 Microvirus H protein (pilot protein) UPF0004 PF00919.20 KDO23853.1 - 1.3e-28 98.9 0.1 2.6e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KDO23853.1 - 3.2e-27 96.0 0.2 9.6e-27 94.4 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 KDO23853.1 - 0.00033 20.6 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 TRAM domain Turandot PF07240.11 KDO23853.1 - 0.089 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Na_Ca_ex PF01699.24 KDO23855.1 - 8.7e-36 123.2 46.9 3.1e-21 75.9 19.2 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4293 PF14126.6 KDO23855.1 - 0.16 12.2 0.3 0.16 12.2 0.3 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF4293) DHHC PF01529.20 KDO23856.1 - 2.4e-31 108.6 9.7 2.4e-31 108.6 9.7 3.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KDO23856.1 - 5.4e-22 77.9 2.1 3.7e-10 40.1 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23856.1 - 2e-20 73.1 1.6 1.6e-08 35.0 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO23856.1 - 1.6e-18 64.9 8.2 0.00089 19.5 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO23856.1 - 3.2e-16 59.2 4.0 2.5e-06 27.7 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO23856.1 - 7.5e-10 38.8 5.0 0.01 16.3 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat DUF4149 PF13664.6 KDO23856.1 - 3.2 8.1 12.9 0.22 11.9 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) HA2 PF04408.23 KDO23857.1 - 1.1e-20 73.9 0.0 2.7e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KDO23857.1 - 1e-14 54.6 0.0 2.7e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KDO23857.1 - 1.7e-13 50.9 0.0 3.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO23857.1 - 2.2e-06 27.6 0.1 6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KDO23857.1 - 2.7e-05 24.5 0.1 5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO23857.1 - 5.4e-05 23.5 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO23857.1 - 0.012 14.7 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KDO23857.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KDO23857.1 - 0.056 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein INT_SG_DDX_CT_C PF15300.6 KDO23857.1 - 0.071 12.9 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Flavi_DEAD PF07652.14 KDO23857.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF1539 PF07560.11 KDO23857.1 - 0.079 13.0 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Zeta_toxin PF06414.12 KDO23857.1 - 0.11 11.8 0.1 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 KDO23857.1 - 0.13 12.3 0.1 0.74 9.8 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KDO23857.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain GyrI-like PF06445.15 KDO23858.1 - 5e-14 52.9 0.0 7.3e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 KDO23858.1 - 1.1e-08 35.4 0.0 1.2e-08 35.3 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein Mannosyl_trans3 PF11051.8 KDO23859.1 - 4.5e-33 114.8 0.0 6.5e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Josephin PF02099.17 KDO23860.1 - 1.5e-25 90.2 0.0 1.4e-17 64.3 0.0 2.0 1 1 1 2 2 2 2 Josephin Arginase PF00491.21 KDO23861.1 - 4.1e-69 233.2 0.0 5.1e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family Pantoate_transf PF02548.15 KDO23863.1 - 3.4e-106 354.4 0.4 4.2e-106 354.1 0.4 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KDO23863.1 - 8.9e-05 22.0 0.3 0.00071 19.1 0.3 2.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NanE PF04131.14 KDO23863.1 - 0.06 12.5 2.5 0.19 10.9 0.2 2.5 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Asp_Glu_race PF01177.22 KDO23863.1 - 0.064 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase FYVE_2 PF02318.16 KDO23864.1 - 8.6e-05 22.7 7.8 0.00016 21.9 7.8 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO23864.1 - 0.00068 19.7 14.6 0.002 18.2 14.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 KDO23864.1 - 0.98 9.3 20.9 0.084 12.8 15.5 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO23864.1 - 3.5 8.0 20.3 1.3 9.4 13.8 2.8 3 0 0 3 3 3 0 Ring finger domain ThiF PF00899.21 KDO23865.1 - 6.3e-64 215.7 0.0 8.8e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KDO23865.1 - 1.2e-18 67.0 0.0 2.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KDO23865.1 - 0.0048 17.0 0.2 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ribosom_S12_S23 PF00164.25 KDO23865.1 - 0.026 14.1 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S12/S23 Sacchrp_dh_NADP PF03435.18 KDO23865.1 - 0.045 14.0 0.2 0.8 10.0 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF2946 PF11162.8 KDO23865.1 - 4.7 7.9 5.8 0.32 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) UCMA PF17085.5 KDO23866.1 - 0.019 15.0 0.8 0.035 14.1 0.8 1.3 1 0 0 1 1 1 0 Unique cartilage matrix associated protein CENP-B_dimeris PF09026.10 KDO23866.1 - 3.4 8.1 9.9 5.8 7.4 8.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LSM PF01423.22 KDO23867.1 - 1.9e-19 69.1 0.2 2.3e-19 68.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KDO23867.1 - 0.081 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Peptidase_M23 PF01551.22 KDO23867.1 - 0.12 12.7 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M23 zf-PARP PF00645.18 KDO23868.1 - 0.0014 19.5 0.0 0.0022 18.8 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PSCyt3 PF07627.11 KDO23868.1 - 0.21 11.9 0.6 0.57 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) ubiquitin PF00240.23 KDO23869.1 - 1.6e-09 37.4 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KDO23869.1 - 0.0095 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO23869.1 - 0.043 14.4 0.0 0.074 13.6 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AZUL PF16558.5 KDO23870.1 - 1.9e-13 50.4 2.3 3.1e-13 49.7 0.2 2.0 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Sugar_tr PF00083.24 KDO23871.1 - 1.8e-32 112.8 7.6 1.9e-32 112.7 7.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3054 PF11255.8 KDO23871.1 - 0.052 14.1 7.3 0.13 12.8 7.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3054) Bax1-I PF01027.20 KDO23871.1 - 0.26 11.1 7.4 0.3 10.9 7.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Amidohydro_1 PF01979.20 KDO23872.1 - 3.7e-15 56.1 0.2 7.6e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Amidohydrolase family Ank_2 PF12796.7 KDO23872.1 - 1e-12 48.5 8.2 1.6e-09 38.2 1.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO23872.1 - 1.8e-08 34.4 3.6 0.00087 19.5 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO23872.1 - 1.2e-06 28.9 7.4 4.3e-05 24.0 0.4 4.0 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Amidohydro_3 PF07969.11 KDO23872.1 - 2.2e-06 27.4 0.0 2.2e-06 27.4 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family Ank_3 PF13606.6 KDO23872.1 - 0.00055 20.2 1.0 11 7.0 0.0 4.1 2 1 1 3 3 3 1 Ankyrin repeat Ank PF00023.30 KDO23872.1 - 0.019 15.4 0.8 12 6.5 0.8 3.6 1 1 0 1 1 1 0 Ankyrin repeat Glucosamine_iso PF01182.20 KDO23873.1 - 6.4e-22 78.5 0.0 9e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase JIP_LZII PF16471.5 KDO23874.1 - 0.018 15.2 0.3 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Rootletin PF15035.6 KDO23874.1 - 0.026 14.6 1.3 0.037 14.0 1.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC144C PF14915.6 KDO23874.1 - 0.053 12.6 2.5 1.5 7.9 0.1 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Fez1 PF06818.15 KDO23874.1 - 0.071 13.6 0.7 0.12 12.8 0.7 1.3 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 KDO23874.1 - 0.25 12.0 1.8 3 8.5 0.1 2.3 1 1 1 2 2 2 0 SlyX ECH_1 PF00378.20 KDO23875.1 - 2.9e-34 118.5 0.3 4.3e-34 117.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 KDO23875.1 - 1.3e-23 83.0 0.1 2.4e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 KDO23875.1 - 1.3e-18 67.6 0.4 4e-17 62.7 0.1 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase SDF PF00375.18 KDO23876.1 - 3.9e-67 227.0 35.2 2.1e-66 224.6 35.2 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4501 PF14946.6 KDO23876.1 - 0.046 13.8 0.3 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) Fascin PF06268.13 KDO23876.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Inositol_P PF00459.25 KDO23877.1 - 6.9e-31 107.8 0.0 1.2e-30 107.0 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family DUF4537 PF15057.6 KDO23879.1 - 0.00046 20.2 0.1 0.00097 19.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.12 KDO23879.1 - 0.00087 19.7 3.3 0.028 14.9 0.5 3.5 3 2 1 4 4 4 1 Agenet domain DUF5097 PF17020.5 KDO23879.1 - 0.038 14.3 0.3 21 5.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5097) DUF4943 PF16301.5 KDO23879.1 - 0.079 13.0 0.0 0.19 11.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4943) LptF_LptG PF03739.14 KDO23879.1 - 0.24 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ClpS PF02617.17 KDO23880.1 - 0.098 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Arf PF00025.21 KDO23881.1 - 8.1e-15 54.7 0.0 1.6e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO23881.1 - 2.5e-08 33.5 0.0 9.7e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KDO23881.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO23881.1 - 0.0028 17.7 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO23881.1 - 0.031 13.6 0.0 0.079 12.3 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KDO23881.1 - 0.055 13.8 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KDO23881.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO23881.1 - 0.2 11.5 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase LSM_int_assoc PF16605.5 KDO23882.1 - 0.021 14.9 0.5 0.021 14.9 0.5 2.2 2 1 0 2 2 2 0 LSM-interacting associated unstructured Acyl_transf_3 PF01757.22 KDO23883.1 - 1.4e-22 80.2 31.9 1.4e-22 80.2 31.9 1.5 2 0 0 2 2 2 1 Acyltransferase family UNC-93 PF05978.16 KDO23887.1 - 1.3e-13 50.9 6.7 1.3e-13 50.9 6.7 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KDO23887.1 - 3.7e-09 36.0 35.8 3.7e-09 36.0 34.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily PX PF00787.24 KDO23889.1 - 1.4e-09 38.0 0.0 2.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF2205 PF10224.9 KDO23889.1 - 3.2e-05 23.8 1.2 0.0013 18.7 1.0 2.5 2 0 0 2 2 2 1 Short coiled-coil protein RRN3 PF05327.11 KDO23889.1 - 0.0027 16.3 1.8 0.0038 15.8 1.8 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Cob_adeno_trans PF01923.18 KDO23889.1 - 0.0072 16.5 2.2 0.0082 16.3 0.1 2.1 2 0 0 2 2 2 1 Cobalamin adenosyltransferase PX PF00787.24 KDO23890.1 - 6.1e-05 23.0 0.0 8.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 PX domain RabGAP-TBC PF00566.18 KDO23891.1 - 1.5e-33 116.3 0.0 2.2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 KDO23891.1 - 3.4e-22 78.8 0.8 4.7e-14 52.7 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23891.1 - 1.6e-17 63.6 7.7 2.8e-07 31.0 1.6 4.1 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO23891.1 - 2.1e-16 59.8 8.6 6.9e-07 29.4 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23891.1 - 8.6e-16 56.5 5.9 2.5e-05 24.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KDO23891.1 - 2.2e-12 46.8 10.9 5.7e-06 26.5 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat fn3 PF00041.21 KDO23891.1 - 9.2e-05 22.7 0.0 0.0015 18.9 0.0 2.6 3 0 0 3 3 3 1 Fibronectin type III domain DUF2369 PF10179.9 KDO23891.1 - 0.022 15.1 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) ABC2_membrane_2 PF12679.7 KDO23892.1 - 2.3 7.4 9.9 3.6 6.8 9.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein HECT PF00632.25 KDO23893.1 - 2.8e-39 135.4 0.0 5.8e-36 124.5 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LPD22 PF18834.1 KDO23893.1 - 0.067 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 Atx10homo_assoc PF09759.9 KDO23894.1 - 9.5e-33 112.2 2.7 4.9e-30 103.5 0.1 3.5 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KDO23894.1 - 0.17 12.0 1.3 0.66 10.1 0.1 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KDO23894.1 - 0.44 10.9 3.5 1.6 9.2 0.1 3.7 3 1 1 4 4 4 0 HEAT repeat CH PF00307.31 KDO23896.1 - 5.3e-48 161.7 2.2 1e-22 80.3 0.4 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EF-hand_1 PF00036.32 KDO23896.1 - 6.8e-12 44.1 2.3 4.8e-06 25.7 0.2 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KDO23896.1 - 9.3e-12 44.6 0.1 3e-06 27.0 0.0 3.2 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_7 PF13499.6 KDO23896.1 - 9.9e-12 45.2 9.1 5.1e-08 33.2 4.6 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KDO23896.1 - 8.1e-11 41.6 5.5 3.5e-07 30.0 1.7 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO23896.1 - 1.1e-08 34.3 1.1 3.7e-05 23.3 0.1 3.3 3 0 0 3 3 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 KDO23896.1 - 5.4e-08 32.8 0.4 1.7e-07 31.2 0.4 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CH_2 PF06294.11 KDO23896.1 - 0.00085 19.4 0.5 2.2 8.4 0.0 3.8 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_5 PF13202.6 KDO23896.1 - 0.0015 17.9 1.2 0.15 11.6 0.1 2.7 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 KDO23896.1 - 0.013 15.8 1.9 0.071 13.4 0.5 3.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO23896.1 - 0.015 15.3 0.1 0.057 13.4 0.1 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KDO23896.1 - 0.023 15.6 0.5 5.6 7.9 0.1 3.2 1 1 1 2 2 2 0 EF-hand domain zf-UBP_var PF17807.1 KDO23896.1 - 0.03 14.1 0.2 0.075 12.8 0.2 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger Spectrin PF00435.21 KDO23896.1 - 0.07 13.6 19.8 6.5 7.3 4.3 5.6 3 2 2 5 5 5 0 Spectrin repeat HTH_Mga PF08280.11 KDO23896.1 - 0.12 12.4 0.0 0.52 10.4 0.0 2.1 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain CLZ PF16526.5 KDO23896.1 - 4 7.9 5.4 11 6.4 0.7 4.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NAD_binding_2 PF03446.15 KDO23896.1 - 4.9 7.3 5.7 17 5.6 0.8 2.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Syntaxin-6_N PF09177.11 KDO23896.1 - 6.5 7.4 12.0 4.9 7.8 0.4 4.9 3 1 1 5 5 4 0 Syntaxin 6, N-terminal CH PF00307.31 KDO23897.1 - 4.2e-43 146.0 0.1 2.4e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KDO23897.1 - 3.4e-11 42.8 0.0 1.9e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KDO23897.1 - 0.0018 18.4 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 CH-like domain in sperm protein Pho88 PF10032.9 KDO23898.1 - 1e-31 109.6 0.0 1.2e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4381 PF14316.6 KDO23900.1 - 0.0049 17.1 0.4 0.017 15.4 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4381) DUF2254 PF10011.9 KDO23900.1 - 0.049 12.4 0.1 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) ELF PF03317.13 KDO23901.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 ELF protein XFP_N PF09364.10 KDO23902.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Peptidase_S9 PF00326.21 KDO23902.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1304 PF06993.12 KDO23902.1 - 0.75 9.8 3.6 1.8 8.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Senescence_reg PF04520.13 KDO23903.1 - 0.0022 18.8 3.2 0.011 16.6 3.2 1.8 1 1 0 1 1 1 1 Senescence regulator AAA_6 PF12774.7 KDO23904.1 - 3.2e-137 456.9 0.0 6.4e-137 455.9 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO23904.1 - 3.4e-123 411.7 0.0 7.3e-123 410.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO23904.1 - 2.9e-89 298.8 0.0 5.4e-89 298.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KDO23904.1 - 3.5e-83 279.4 0.0 2.4e-82 276.6 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KDO23904.1 - 3.4e-80 268.3 0.0 5.4e-78 261.1 0.1 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO23904.1 - 4.9e-60 202.1 0.0 5.7e-55 185.6 0.0 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KDO23904.1 - 1.8e-50 171.9 11.7 2.9e-50 171.2 11.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KDO23904.1 - 2e-47 161.0 0.0 4e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO23904.1 - 3.9e-40 136.6 0.0 3.7e-39 133.5 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KDO23904.1 - 2.6e-16 59.6 0.1 1.1e-15 57.6 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO23904.1 - 2.7e-15 56.6 0.0 0.03 14.3 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.29 KDO23904.1 - 4.3e-11 43.4 0.1 0.0096 16.4 0.0 3.9 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 KDO23904.1 - 7.9e-08 32.5 0.1 3e-07 30.6 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KDO23904.1 - 4.6e-07 30.2 0.2 1.6 9.0 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KDO23904.1 - 8.7e-06 26.3 0.1 0.32 11.6 0.0 4.5 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 KDO23904.1 - 5.2e-05 23.7 5.2 4.5 7.6 0.2 6.5 4 2 0 4 4 4 1 AAA ATPase domain NACHT PF05729.12 KDO23904.1 - 0.0002 21.3 0.1 0.003 17.5 0.0 3.1 2 0 0 2 2 2 1 NACHT domain SHE3 PF17078.5 KDO23904.1 - 0.024 14.3 2.0 0.065 12.9 0.2 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 RNA_helicase PF00910.22 KDO23904.1 - 0.064 13.7 0.1 23 5.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase TsaE PF02367.17 KDO23904.1 - 0.21 11.6 3.0 38 4.3 0.2 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KDO23904.1 - 0.27 10.9 1.0 3.2 7.4 0.1 3.2 4 0 0 4 4 4 0 Sigma-54 interaction domain T2SSE PF00437.20 KDO23904.1 - 0.28 10.2 6.8 2.9 6.9 0.0 3.3 4 0 0 4 4 4 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KDO23904.1 - 1.3 8.2 4.1 6 6.1 0.1 3.6 4 0 0 4 4 4 0 Zeta toxin BTB PF00651.31 KDO23905.1 - 0.00015 22.0 0.0 0.00045 20.4 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF758 PF05527.11 KDO23905.1 - 0.019 15.0 0.2 0.043 13.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF758) UIM PF02809.20 KDO23905.1 - 0.85 9.7 3.6 2.5 8.2 3.6 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Nuc_sug_transp PF04142.15 KDO23906.1 - 2.3e-21 76.3 7.3 2.7e-21 76.1 7.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KDO23906.1 - 9.5e-07 28.3 5.8 1.4e-06 27.8 5.8 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 KDO23906.1 - 0.0015 18.7 7.9 0.0015 18.7 7.9 2.7 2 1 0 2 2 2 1 EamA-like transporter family TPR_1 PF00515.28 KDO23909.1 - 1e-16 60.0 5.7 0.00038 20.2 0.4 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KDO23909.1 - 3e-15 56.3 8.5 1.4e-06 28.5 0.7 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23909.1 - 2.8e-14 52.0 6.5 0.0064 16.5 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO23909.1 - 3.1e-13 49.1 7.9 2e-05 24.3 0.5 4.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO23909.1 - 2e-08 33.8 9.6 0.0011 19.0 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO23909.1 - 2.4e-07 30.3 4.7 0.0048 16.8 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO23909.1 - 0.00081 19.0 1.3 0.24 11.1 0.0 4.2 3 1 0 3 3 3 1 TPR repeat RPN7 PF10602.9 KDO23909.1 - 0.0099 15.6 0.5 0.12 12.1 0.4 2.4 1 1 1 2 2 2 1 26S proteasome subunit RPN7 RunxI PF08504.11 KDO23909.1 - 0.033 14.9 0.0 0.065 13.9 0.0 1.5 1 0 0 1 1 1 0 Runx inhibition domain SNAP PF14938.6 KDO23909.1 - 0.035 13.5 0.9 0.063 12.7 0.1 1.8 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP GAS PF13851.6 KDO23909.1 - 0.038 13.3 0.1 0.038 13.3 0.1 1.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_15 PF13429.6 KDO23909.1 - 0.15 11.3 1.4 0.9 8.7 0.0 2.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23909.1 - 0.69 10.9 3.0 58 4.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO23909.1 - 0.8 10.4 5.0 27 5.5 0.0 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat DNA_pol_A_exo1 PF01612.20 KDO23910.1 - 2.7e-15 56.5 0.0 4.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 KDO23911.1 - 2.4e-54 184.4 0.0 3.5e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23911.1 - 2.7e-37 128.5 0.0 7.8e-37 126.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase ACT_7 PF13840.6 KDO23911.1 - 1.2e-20 73.0 0.0 2.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain SH3_1 PF00018.28 KDO23911.1 - 4.2e-07 29.5 0.2 1.5e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KDO23911.1 - 4.1e-05 23.3 0.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KDO23911.1 - 0.00034 20.2 0.0 0.00082 19.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 KDO23911.1 - 0.014 14.7 0.5 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KDO23911.1 - 0.038 13.9 0.2 3.3 7.5 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mito_fiss_Elm1 PF06258.11 KDO23912.1 - 7.9e-61 205.9 0.1 1.3e-60 205.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Abhydrolase_6 PF12697.7 KDO23912.1 - 1.2e-05 26.0 0.7 1.2e-05 26.0 0.7 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO23912.1 - 0.00052 19.3 0.3 0.21 10.8 0.1 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Epimerase_2 PF02350.19 KDO23912.1 - 0.045 12.6 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Abhydrolase_1 PF00561.20 KDO23912.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Reprolysin_2 PF13574.6 KDO23912.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NOD PF06816.13 KDO23914.1 - 0.26 10.9 0.5 1.1 8.9 0.0 2.3 3 0 0 3 3 3 0 NOTCH protein DUF4419 PF14388.6 KDO23915.1 - 1.4e-93 313.7 0.0 1.6e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.6 KDO23916.1 - 6.5e-90 301.6 0.0 7.6e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.6 KDO23917.1 - 1.6e-93 313.5 0.0 1.8e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Rotamase_3 PF13616.6 KDO23918.1 - 9.8e-18 64.8 0.0 1.4e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KDO23918.1 - 9.8e-14 52.1 0.0 1.4e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KDO23918.1 - 0.0019 19.0 0.0 0.0024 18.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Cpn60_TCP1 PF00118.24 KDO23920.1 - 3.9e-169 563.4 1.2 4.4e-169 563.2 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Piezo_RRas_bdg PF12166.8 KDO23920.1 - 0.06 12.6 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain WD40 PF00400.32 KDO23921.1 - 3.9e-19 68.6 23.3 0.0013 19.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KDO23921.1 - 0.00017 20.4 2.0 0.17 10.5 0.1 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 VID27 PF08553.10 KDO23921.1 - 0.0039 16.3 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 KDO23921.1 - 0.011 16.1 3.5 2.4 8.8 0.0 5.1 5 1 0 5 5 5 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KDO23921.1 - 0.015 15.6 1.1 2.3 8.6 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RNase_P_Rpp14 PF01900.19 KDO23922.1 - 2.4e-07 30.9 0.0 3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Pkinase_Tyr PF07714.17 KDO23923.1 - 9.1e-28 97.2 0.0 1.2e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO23923.1 - 4.3e-20 72.2 0.0 6.4e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MGC-24 PF05283.11 KDO23923.1 - 8.6e-05 23.0 0.4 8.6e-05 23.0 0.4 3.4 3 0 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 KDO23923.1 - 0.0029 17.5 0.2 0.0057 16.5 0.2 1.4 1 0 0 1 1 1 1 Syndecan domain Cytomega_TRL10 PF06084.11 KDO23923.1 - 0.0031 17.5 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 Cytomegalovirus TRL10 protein PTP_tm PF18861.1 KDO23923.1 - 0.059 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mid2 PF04478.12 KDO23923.1 - 0.1 12.4 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4366 PF14283.6 KDO23923.1 - 0.17 11.9 0.2 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Ribosomal_L27e PF01777.18 KDO23924.1 - 1.5e-30 105.4 6.1 2e-30 105.0 6.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KDO23924.1 - 0.00063 19.6 1.8 0.00063 19.6 1.8 2.2 3 0 0 3 3 3 1 KOW motif zf-C2H2_jaz PF12171.8 KDO23925.1 - 2.8e-06 27.5 5.6 0.00017 21.8 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KDO23925.1 - 1.6e-05 25.4 4.2 0.016 16.0 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KDO23925.1 - 4.6e-05 23.6 3.2 0.042 14.3 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KDO23925.1 - 0.0056 16.9 3.1 0.12 12.6 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KDO23925.1 - 0.017 15.5 3.5 1.1 9.7 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KDO23925.1 - 0.12 12.3 9.2 2 8.4 3.1 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF629 PF04780.12 KDO23925.1 - 0.15 10.6 0.8 0.21 10.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-BED PF02892.15 KDO23925.1 - 0.2 11.7 7.2 2.4 8.3 2.0 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KDO23925.1 - 0.23 11.8 3.4 11 6.4 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KDO23925.1 - 0.26 11.3 3.1 6.4 6.9 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.13 KDO23925.1 - 1.6 8.8 5.7 13 5.9 1.8 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Mlo PF03094.15 KDO23926.1 - 1.1e-05 24.0 5.0 0.017 13.5 0.3 2.4 2 0 0 2 2 2 2 Mlo family Spc110_C PF18520.1 KDO23926.1 - 0.077 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain PACT_coil_coil PF10495.9 KDO23926.1 - 0.14 12.7 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein malic PF00390.19 KDO23927.1 - 2.4e-74 249.1 0.0 4.1e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KDO23927.1 - 1.5e-54 185.0 0.3 2.2e-54 184.5 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Pyr_redox_2 PF07992.14 KDO23927.1 - 0.088 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF525 PF04379.14 KDO23928.1 - 1.2e-20 73.5 0.0 1.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 ApaG domain zf-CCHC_3 PF13917.6 KDO23931.1 - 5.8e-07 29.4 0.1 5.8e-07 29.4 0.1 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KDO23931.1 - 0.032 14.3 1.6 0.032 14.3 1.6 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF2457 PF10446.9 KDO23931.1 - 0.063 12.4 30.4 0.087 12.0 30.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-CCHC_6 PF15288.6 KDO23931.1 - 0.086 12.7 3.5 0.24 11.3 3.5 1.8 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.6 KDO23931.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 CpXC protein GREB1 PF15782.5 KDO23931.1 - 1.4 6.0 12.3 1.5 5.8 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CNDH2_N PF06278.11 KDO23931.1 - 1.9 8.7 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Apt1 PF10351.9 KDO23931.1 - 2.3 6.9 25.1 3.2 6.5 25.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain ORC6 PF05460.13 KDO23931.1 - 3.1 7.0 20.7 4.5 6.4 20.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SRP-alpha_N PF04086.13 KDO23931.1 - 3.4 7.5 26.9 4.3 7.2 26.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 KDO23931.1 - 7.7 4.5 19.0 9.3 4.2 19.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 KDO23931.1 - 9.6 5.1 13.3 12 4.7 13.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PI3_PI4_kinase PF00454.27 KDO23932.1 - 2.1e-25 90.0 0.0 4.3e-21 75.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF5126 PF17166.4 KDO23933.1 - 0.025 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) UCH PF00443.29 KDO23934.1 - 3.9e-34 118.3 0.0 6.2e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO23934.1 - 3.8e-06 26.7 0.2 0.0014 18.3 0.3 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pdase_C33_assoc PF14756.6 KDO23934.1 - 0.013 15.5 0.0 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Peptidase_C33-associated domain Mito_morph_reg PF14972.6 KDO23934.1 - 0.11 12.1 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator EF-hand_6 PF13405.6 KDO23934.1 - 0.23 11.5 0.4 18 5.6 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain ApbE PF02424.15 KDO23935.1 - 0.064 12.8 0.5 0.3 10.6 0.5 1.9 1 1 0 1 1 1 0 ApbE family FYVE PF01363.21 KDO23936.1 - 5.1e-20 71.4 5.8 5.1e-20 71.4 5.8 2.2 2 1 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 KDO23936.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYVE_2 PF02318.16 KDO23936.1 - 0.0011 19.1 3.1 0.0011 19.1 3.1 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger PLATZ PF04640.14 KDO23936.1 - 0.13 12.9 0.6 0.13 12.9 0.6 2.7 2 1 0 2 2 2 0 PLATZ transcription factor Ntox1 PF15500.6 KDO23938.1 - 0.076 13.4 1.1 2.2 8.7 0.2 2.3 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 MCPVI PF02993.14 KDO23938.1 - 0.64 9.8 3.1 1.1 9.1 3.1 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Hydrolase_4 PF12146.8 KDO23939.1 - 4.1e-12 45.9 0.2 5.9e-10 38.8 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KDO23939.1 - 7.8e-07 28.9 0.0 1.9e-05 24.4 0.0 2.1 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KDO23939.1 - 4.5e-06 27.4 0.0 1e-05 26.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO23939.1 - 2.3e-05 24.2 0.4 0.00077 19.2 0.3 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold zf-RanBP PF00641.18 KDO23939.1 - 0.00076 18.7 3.5 0.00076 18.7 3.5 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others PhoPQ_related PF10142.9 KDO23939.1 - 0.00088 18.0 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.21 KDO23939.1 - 0.018 14.5 0.1 0.53 9.7 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.13 KDO23939.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 KDO23939.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 Putative esterase DUF35_N PF12172.8 KDO23939.1 - 0.19 11.6 1.6 0.45 10.4 1.6 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 KDO23941.1 - 4.3e-65 219.7 0.0 5.6e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23941.1 - 4.9e-29 101.4 0.0 1.2e-28 100.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO23941.1 - 2e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO23941.1 - 0.0002 20.8 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO23941.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KDO23941.1 - 0.019 14.6 0.3 0.052 13.1 0.3 1.7 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KDO23941.1 - 0.046 13.3 0.1 0.098 12.3 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Mal_decarbox_Al PF16957.5 KDO23941.1 - 0.046 12.1 0.0 0.069 11.5 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Seadorna_VP7 PF07387.11 KDO23941.1 - 0.086 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KDO23941.1 - 0.35 9.6 1.5 0.32 9.7 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO23942.1 - 7.6e-14 51.6 0.0 5.1e-13 48.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KDO23942.1 - 3.1e-12 46.4 0.0 8.3e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KDO23942.1 - 0.00043 19.9 0.0 0.00095 18.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KDO23943.1 - 3.2e-46 157.8 0.0 4.2e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23943.1 - 7.5e-41 140.1 0.0 9.1e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO23943.1 - 0.007 15.2 0.0 0.0092 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO23943.1 - 0.01 15.2 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO23943.1 - 0.017 14.0 0.0 0.026 13.5 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 KDO23944.1 - 3.1e-16 59.7 4.8 9.3e-09 35.8 0.8 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO23944.1 - 6.1e-14 52.2 3.1 1.1e-08 35.4 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO23944.1 - 4.8e-12 45.7 8.2 0.017 15.5 0.2 4.1 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KDO23944.1 - 9.3e-12 44.1 4.4 0.0018 18.6 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO23944.1 - 4.7e-06 26.8 6.1 0.12 12.7 0.5 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO23945.1 - 1.7e-40 139.1 0.0 5e-38 131.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23945.1 - 4.3e-33 114.7 0.0 4.1e-31 108.2 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO23945.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO23945.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KDO23945.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 KDO23947.1 - 1.7e-30 106.3 30.4 2e-17 63.2 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO23947.1 - 4.3e-16 58.8 32.1 7.5e-12 44.8 6.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf70 PF17382.2 KDO23947.1 - 0.12 12.8 1.8 0.64 10.5 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized Ycf70-like TYW3 PF02676.14 KDO23949.1 - 2.2e-43 148.1 0.1 1.1e-34 119.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase TYW3 Kelch_4 PF13418.6 KDO23949.1 - 9.9e-33 111.9 0.6 8.8e-07 28.8 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO23949.1 - 2.4e-27 94.3 0.1 1.3e-05 25.3 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Met_10 PF02475.16 KDO23949.1 - 3.6e-27 95.4 0.0 6.4e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_1 PF01344.25 KDO23949.1 - 1.9e-26 91.4 0.3 4.7e-06 26.1 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KDO23949.1 - 8.8e-24 83.0 5.6 1e-05 25.4 0.1 6.7 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KDO23949.1 - 6.6e-18 64.5 7.8 0.00061 20.0 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KDO23949.1 - 1.7e-10 40.4 3.6 0.17 11.9 0.0 5.1 5 1 0 5 5 5 4 Kelch motif Methyltransf_15 PF09445.10 KDO23949.1 - 0.00089 18.9 0.0 0.0057 16.3 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KDO23949.1 - 0.04 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain RAG2 PF03089.14 KDO23949.1 - 0.088 11.8 0.1 0.25 10.3 0.0 1.9 1 1 0 1 1 1 0 Recombination activating protein 2 Rap_GAP PF02145.15 KDO23950.1 - 4.1e-35 121.0 0.0 7.4e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.8 KDO23950.1 - 8.2e-23 81.0 8.1 1.6e-19 70.2 0.3 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3384) HEAT PF02985.22 KDO23950.1 - 0.0061 16.7 4.1 1.4 9.3 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KDO23950.1 - 0.048 14.0 7.9 11 6.4 0.1 5.3 4 1 0 4 4 4 0 HEAT repeats Tuberin PF03542.16 KDO23950.1 - 1.9 7.5 4.7 15 4.6 0.3 3.1 2 1 1 3 3 3 0 Tuberin RRM_1 PF00076.22 KDO23951.1 - 3.1e-40 135.8 0.2 1.2e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO23951.1 - 8.1e-05 22.7 0.1 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KDO23951.1 - 0.0063 16.2 0.1 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain PHM7_cyt PF14703.6 KDO23951.1 - 0.022 15.0 0.1 0.53 10.5 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter C2 PF00168.30 KDO23952.1 - 9.8e-62 205.7 0.1 7.2e-18 64.8 0.0 8.2 7 0 0 7 7 7 5 C2 domain PH PF00169.29 KDO23952.1 - 7.2e-15 55.4 0.0 2.8e-14 53.5 0.0 2.1 1 0 0 1 1 1 1 PH domain DEP PF00610.21 KDO23952.1 - 1.9e-07 31.0 0.4 0.00033 20.7 0.0 3.5 4 0 0 4 4 4 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1918 PF08940.11 KDO23952.1 - 0.00051 19.6 0.0 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1918) Tudor_3 PF18115.1 KDO23952.1 - 0.064 13.1 1.3 13 5.7 0.1 3.3 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain SH3_2 PF07653.17 KDO23953.1 - 1.4e-09 37.5 0.0 2.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KDO23953.1 - 1.8e-09 37.3 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KDO23953.1 - 1.1e-06 28.2 0.0 2.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain hSH3 PF14603.6 KDO23953.1 - 0.011 16.2 0.6 0.062 13.7 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain Glutaredoxin PF00462.24 KDO23954.1 - 5.8e-18 64.9 0.1 8.7e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 KDO23954.1 - 0.0016 18.3 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KDO23954.1 - 0.003 17.7 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin DSBA PF01323.20 KDO23954.1 - 0.0035 17.2 0.2 0.2 11.4 0.0 2.1 1 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 KDO23954.1 - 0.0054 17.2 0.1 0.0094 16.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KDO23954.1 - 0.032 14.6 0.0 0.043 14.2 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KDO23954.1 - 0.1 12.7 0.7 0.85 9.7 0.7 2.2 1 1 0 1 1 1 0 Thioredoxin domain GST_N_3 PF13417.6 KDO23954.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain DNA_ligase_A_N PF04675.14 KDO23955.1 - 6e-35 121.1 0.1 9.5e-35 120.5 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KDO23955.1 - 9.6e-28 97.2 0.0 1.6e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KDO23955.1 - 1.7e-17 63.8 0.0 5.6e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KDO23955.1 - 3.5e-11 43.4 0.0 2.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO23955.1 - 1.6e-07 31.6 0.0 0.0014 19.0 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KDO23955.1 - 3.8e-05 23.5 0.1 0.022 14.7 0.0 3.2 3 0 0 3 3 3 1 twin BRCT domain LIG3_BRCT PF16759.5 KDO23955.1 - 0.045 14.0 0.0 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 KDO23955.1 - 0.14 12.3 0.7 0.37 10.9 0.7 1.7 1 0 0 1 1 1 0 DNA ligase IV FYVE PF01363.21 KDO23956.1 - 2.5e-16 59.6 9.5 6e-16 58.3 9.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger FIST PF08495.10 KDO23956.1 - 1.1e-11 45.1 1.2 8.8e-11 42.1 0.2 2.6 2 0 0 2 2 2 1 FIST N domain FIST_C PF10442.9 KDO23956.1 - 1.9e-10 40.8 0.0 4.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 FIST C domain C1_1 PF00130.22 KDO23956.1 - 0.0048 16.7 2.7 0.012 15.5 2.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 KDO23956.1 - 0.011 15.9 4.2 0.034 14.3 4.2 1.9 1 0 0 1 1 1 0 B-box zinc finger FYVE_2 PF02318.16 KDO23956.1 - 1.2 9.3 5.2 2.6 8.3 5.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DEAD PF00270.29 KDO23957.1 - 5.5e-49 166.3 0.0 1.2e-48 165.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO23957.1 - 8.2e-25 87.3 0.0 5.7e-24 84.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RSRP PF17069.5 KDO23957.1 - 1.4 8.4 38.8 2.7 7.5 38.8 1.5 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Scytalone_dh PF02982.14 KDO23958.1 - 0.054 13.3 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Scytalone dehydratase bZIP_2 PF07716.15 KDO23959.1 - 7.8e-09 35.5 11.9 1.2e-08 34.9 11.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO23959.1 - 4.1e-07 30.0 11.4 7.5e-07 29.2 11.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KDO23959.1 - 0.00098 19.6 7.8 0.0014 19.1 7.2 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor SnoaL_2 PF12680.7 KDO23959.1 - 0.013 16.1 0.0 0.034 14.8 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Cep57_CLD PF14073.6 KDO23959.1 - 0.014 15.4 3.1 0.021 14.8 3.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 SnoaL PF07366.12 KDO23959.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase LCD1 PF09798.9 KDO23959.1 - 0.034 12.7 1.0 0.049 12.1 1.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF1465 PF07323.12 KDO23959.1 - 0.2 11.5 4.9 0.19 11.6 3.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) TTL PF03133.15 KDO23960.1 - 1.8e-77 260.4 3.0 2.1e-75 253.6 3.0 2.1 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO23960.1 - 5.7e-09 35.6 0.0 0.0005 19.4 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO23960.1 - 6.2e-05 22.4 0.0 0.0064 15.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 KDO23960.1 - 0.11 12.0 0.0 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain TPR_10 PF13374.6 KDO23962.1 - 8.4e-07 28.7 4.1 0.021 14.7 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO23962.1 - 1.3e-06 28.6 5.3 0.008 16.4 0.1 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO23962.1 - 1.8e-05 24.6 1.5 0.69 10.3 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO23962.1 - 3.8e-05 23.5 9.3 0.021 14.9 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO23962.1 - 4.3e-05 23.2 1.2 0.0041 17.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO23962.1 - 0.0022 18.6 12.9 7.6 7.6 0.1 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO23962.1 - 0.0073 16.1 2.0 3.6 7.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO23962.1 - 0.017 15.7 7.7 1.7 9.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO23962.1 - 0.21 12.2 12.5 0.53 11.0 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO23962.1 - 3 8.4 12.8 7.8 7.1 1.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat PC_rep PF01851.22 KDO23963.1 - 3.8e-05 23.9 4.5 1.2 9.7 0.0 4.3 4 0 0 4 4 4 3 Proteasome/cyclosome repeat APC1_C PF18122.1 KDO23963.1 - 0.047 13.6 2.3 0.054 13.4 0.8 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain C2 PF00168.30 KDO23964.1 - 5.3e-10 39.5 0.0 1.3e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 C2 domain CBX7_C PF17218.3 KDO23964.1 - 0.044 13.5 0.3 0.081 12.7 0.3 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif C2 PF00168.30 KDO23965.1 - 4.9e-10 39.6 0.0 1.2e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 C2 domain CBX7_C PF17218.3 KDO23965.1 - 0.043 13.5 0.3 0.081 12.7 0.3 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif MFS_1 PF07690.16 KDO23966.1 - 9.6e-07 28.0 0.0 1e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 KDO23966.1 - 0.00042 18.7 0.0 0.00042 18.7 0.0 1.0 1 0 0 1 1 1 1 BT1 family MFS_1_like PF12832.7 KDO23966.1 - 0.035 13.0 0.2 0.039 12.8 0.2 1.0 1 0 0 1 1 1 0 MFS_1 like family Phage_holin_3_6 PF07332.11 KDO23966.1 - 0.079 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3953 PF13129.6 KDO23966.1 - 0.084 12.7 1.1 0.23 11.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) MFS_1 PF07690.16 KDO23967.1 - 2.7e-40 138.4 66.7 1.2e-27 96.8 42.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO23967.1 - 2.3e-05 23.4 12.7 2.3e-05 23.4 12.7 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO23968.1 - 2.4e-33 115.5 37.7 6.5e-18 64.8 15.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO23968.1 - 4.9e-12 45.4 23.2 8.3e-08 31.5 9.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KDO23968.1 - 3.5e-05 22.6 25.7 0.0055 15.3 4.9 4.2 2 2 1 3 3 3 3 MFS/sugar transport protein BT1 PF03092.16 KDO23968.1 - 0.029 12.6 6.1 0.0054 15.0 1.7 2.0 2 0 0 2 2 2 0 BT1 family NIF PF03031.18 KDO23969.1 - 6.8e-39 133.1 0.6 1e-38 132.5 0.6 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 KDO23969.1 - 0.024 14.7 0.0 0.095 12.8 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KDO23970.1 - 1.5e-71 240.9 0.0 1.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO23970.1 - 2.1e-40 138.6 0.0 2.8e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO23970.1 - 0.017 14.4 0.0 0.047 13.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO23970.1 - 0.059 12.3 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 KDO23970.1 - 0.16 12.7 2.0 0.54 11.0 1.9 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain eIF3m_C_helix PF18005.1 KDO23970.1 - 0.23 11.2 0.6 0.49 10.1 0.6 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Elicitin PF00964.17 KDO23971.1 - 0.009 16.1 8.5 0.0092 16.1 7.4 1.5 1 1 0 1 1 1 1 Elicitin Sec23_trunk PF04811.15 KDO23972.1 - 1.7e-71 240.7 0.0 2.4e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KDO23972.1 - 8.8e-28 96.9 0.0 2.3e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KDO23972.1 - 9.3e-21 73.6 0.0 2.9e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KDO23972.1 - 3.6e-16 58.9 3.3 6.8e-16 58.0 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KDO23972.1 - 5.8e-11 42.1 0.0 2.1e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Gelsolin repeat Paramyxo_P PF01806.17 KDO23972.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Fringe PF02434.16 KDO23973.1 - 2e-09 37.3 0.0 4.5e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Fringe-like RNA_pol_Rpb1_1 PF04997.12 KDO23974.1 - 7.4e-86 288.3 0.1 1.5e-85 287.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KDO23974.1 - 3.6e-75 251.8 0.1 6.2e-75 251.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KDO23974.1 - 9.6e-37 126.3 0.0 1.8e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 KDO23974.1 - 5.3e-30 104.7 0.0 1e-29 103.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 KDO23974.1 - 8.7e-28 96.4 0.0 1.8e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-RING_7 PF02591.15 KDO23974.1 - 8.8 6.6 7.2 2.5 8.4 0.3 3.5 4 0 0 4 4 4 0 C4-type zinc ribbon domain Lactamase_B_2 PF12706.7 KDO23976.1 - 3.5e-34 118.1 0.1 4.8e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KDO23976.1 - 8.9e-12 45.2 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO23976.1 - 0.0036 17.3 0.2 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BCDHK_Adom3 PF10436.9 KDO23977.1 - 1.9e-26 92.8 1.0 3.9e-14 52.8 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KDO23977.1 - 1.3e-07 32.1 0.0 8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KDO23977.1 - 0.2 11.5 0.0 0.59 10.0 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FCSD-flav_bind PF09242.11 KDO23978.1 - 0.19 12.1 2.4 0.2 12.1 0.2 2.3 2 0 0 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Methyltransf_16 PF10294.9 KDO23979.1 - 4.6e-20 72.1 0.1 1.1e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KDO23979.1 - 1.1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO23979.1 - 0.00032 21.4 0.3 0.00064 20.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KDO23979.1 - 0.0018 17.9 0.1 0.0043 16.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KDO23979.1 - 0.0049 17.5 0.0 0.009 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO23979.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_C10 PF01640.17 KDO23979.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase C10 family MitMem_reg PF13012.6 KDO23980.1 - 1.2e-23 83.6 0.0 1.9e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KDO23980.1 - 4.8e-21 74.9 0.0 7.4e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ion_trans PF00520.31 KDO23981.1 - 4.4e-160 530.4 73.2 3e-44 151.1 6.2 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KDO23981.1 - 3.7e-08 33.0 0.0 8.9e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KDO23981.1 - 5e-06 25.5 69.7 0.013 14.2 1.0 10.6 9 2 2 11 11 11 8 Polycystin cation channel EF-hand_1 PF00036.32 KDO23981.1 - 0.021 14.4 0.0 0.069 12.7 0.0 2.0 1 0 0 1 1 1 0 EF hand Ion_trans PF00520.31 KDO23983.1 - 3.2e-165 547.3 87.0 1.6e-45 155.3 5.6 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KDO23983.1 - 4.2e-08 32.8 0.0 9.8e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KDO23983.1 - 0.062 12.0 79.7 0.02 13.6 1.3 10.1 8 3 2 10 10 10 0 Polycystin cation channel DUF4834 PF16118.5 KDO23983.1 - 3 8.8 3.7 1.5e+02 3.4 0.2 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) AAA_6 PF12774.7 KDO23984.1 - 1e-156 520.9 0.0 6.2e-156 518.4 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO23984.1 - 3.2e-128 428.2 1.8 3.2e-128 428.2 1.8 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KDO23984.1 - 1.3e-109 366.1 0.0 9.4e-109 363.3 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KDO23984.1 - 1.5e-94 316.1 0.2 3.6e-93 311.7 0.0 2.9 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO23984.1 - 7.4e-93 309.7 2.7 8.8e-91 302.9 0.6 3.0 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO23984.1 - 1.5e-75 252.7 0.0 2e-74 249.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KDO23984.1 - 7.6e-58 195.0 0.0 2.7e-57 193.1 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO23984.1 - 3.2e-46 156.3 0.0 4.7e-44 149.3 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KDO23984.1 - 8.3e-40 136.9 6.8 2.1e-39 135.6 6.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KDO23984.1 - 8.5e-28 97.0 0.0 5.2e-27 94.5 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO23984.1 - 6.6e-17 61.6 0.1 3.7e-16 59.1 0.3 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO23984.1 - 5.7e-15 55.5 0.0 0.00023 21.1 0.0 6.4 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO23984.1 - 3.1e-06 27.0 0.0 0.00094 19.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 KDO23984.1 - 7.5e-06 25.2 0.0 7.4e-05 21.9 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 KDO23984.1 - 2.1e-05 25.0 0.0 0.074 13.5 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO23984.1 - 0.0012 19.2 3.1 0.074 13.4 0.0 4.5 5 0 0 5 5 3 1 AAA ATPase domain AAA_18 PF13238.6 KDO23984.1 - 0.0071 16.9 0.0 16 6.0 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 KDO23984.1 - 0.01 16.1 0.2 0.38 11.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KDO23984.1 - 0.018 15.3 0.0 0.69 10.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KDO23984.1 - 0.019 15.2 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Plasmid_RAQPRD PF09686.10 KDO23984.1 - 0.02 15.1 0.0 1.2 9.4 0.0 3.6 2 1 1 3 3 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RNA_helicase PF00910.22 KDO23984.1 - 0.022 15.2 0.0 7.1 7.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 KDO23984.1 - 0.03 14.4 0.0 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 KDO23984.1 - 0.038 13.1 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KDO23984.1 - 0.054 14.0 0.0 0.48 10.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 KDO23984.1 - 0.06 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 KDO23984.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 KDO23984.1 - 0.073 12.4 0.1 0.25 10.7 0.1 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KDO23984.1 - 0.11 12.3 0.1 1.4 8.7 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KDO23984.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain SKA2 PF16740.5 KDO23984.1 - 0.29 10.9 2.3 17 5.2 0.3 3.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 KDO23984.1 - 0.87 10.0 7.1 13 6.3 0.1 4.1 3 0 0 3 3 2 0 Snapin/Pallidin MerR-DNA-bind PF09278.11 KDO23984.1 - 2.1 9.0 4.5 1e+02 3.6 0.6 4.3 4 0 0 4 4 2 0 MerR, DNA binding DUF5082 PF16888.5 KDO23984.1 - 3.6 7.9 6.2 1.1 9.5 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Cyclin_N PF00134.23 KDO23985.1 - 3.4e-19 68.8 0.1 5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO23985.1 - 1.3e-14 54.3 0.1 3.5e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain DHR10 PF18595.1 KDO23986.1 - 0.015 15.4 0.6 0.027 14.5 0.6 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KDO23986.1 - 0.022 15.4 0.0 0.066 13.8 0.0 1.8 1 0 0 1 1 1 0 SlyX ABC_tran_CTD PF16326.5 KDO23986.1 - 0.03 14.6 0.5 0.12 12.7 0.0 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 KDO23986.1 - 0.038 14.4 0.1 0.079 13.4 0.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin EF-hand_1 PF00036.32 KDO23987.1 - 3.3e-16 57.6 0.5 1e-06 27.8 0.0 3.5 3 1 1 4 4 4 2 EF hand Ank_4 PF13637.6 KDO23987.1 - 1.1e-15 57.7 0.3 2.7e-13 50.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO23987.1 - 4.3e-15 56.1 0.2 9.7e-15 54.9 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) EF-hand_7 PF13499.6 KDO23987.1 - 5.9e-15 55.5 0.0 2e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO23987.1 - 1.5e-14 52.6 0.4 6e-06 25.8 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain Ank_5 PF13857.6 KDO23987.1 - 3.7e-14 52.6 0.2 1.4e-05 25.3 0.4 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 KDO23987.1 - 7.9e-13 48.1 0.1 1.8e-08 34.1 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO23987.1 - 3.8e-11 42.0 7.2 2.2e-05 23.7 0.0 4.5 4 1 1 5 5 5 2 EF hand Ank_3 PF13606.6 KDO23987.1 - 4.3e-11 42.0 0.2 0.0013 19.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO23987.1 - 6.3e-11 42.2 0.3 0.0015 18.9 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeat F-box PF00646.33 KDO23988.1 - 1.3e-08 34.4 0.6 3.9e-08 33.0 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KDO23988.1 - 2.5e-05 24.1 0.5 6.4e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 F-box-like IQ PF00612.27 KDO23989.1 - 0.072 12.9 0.2 0.072 12.9 0.2 5.2 5 0 0 5 5 5 0 IQ calmodulin-binding motif ARD PF03079.14 KDO23989.1 - 0.68 10.1 3.0 1.9 8.7 3.0 1.7 1 0 0 1 1 1 0 ARD/ARD' family LRR_6 PF13516.6 KDO23990.1 - 0.00013 21.8 8.2 2.1 8.6 0.4 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KDO23990.1 - 0.14 12.7 8.1 0.065 13.7 2.2 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO23990.1 - 0.2 11.5 8.2 0.083 12.7 2.4 3.3 2 1 2 4 4 4 0 Leucine rich repeat AAA_28 PF13521.6 KDO23991.1 - 1.1e-25 90.8 0.0 2e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 KDO23991.1 - 0.00021 20.6 0.0 0.00032 20.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.10 KDO23991.1 - 0.00044 19.8 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MeaB PF03308.16 KDO23991.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 KDO23991.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 KDO23991.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KDO23991.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase SecE PF00584.20 KDO23992.1 - 6.7e-15 54.8 0.1 7.7e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ank_4 PF13637.6 KDO23993.1 - 3.8e-17 62.4 4.1 2.4e-08 34.4 0.3 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO23993.1 - 8.2e-16 56.5 2.2 3.6e-06 26.9 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO23993.1 - 1.7e-12 47.1 5.4 2.1e-05 24.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO23993.1 - 5.7e-12 46.1 0.9 1.5e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO23993.1 - 3.6e-10 39.9 1.4 2e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SDF PF00375.18 KDO23994.1 - 5.1e-93 312.2 35.4 5.8e-93 312.0 35.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family BBS1 PF14779.6 KDO23995.1 - 6.7e-95 317.3 0.0 2.2e-94 315.6 0.0 1.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 KDO23995.1 - 1.7e-06 28.0 0.0 0.24 11.4 0.0 3.7 3 1 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 KDO23995.1 - 0.013 14.9 0.0 9.4 5.5 0.0 3.2 2 1 0 3 3 3 0 PTHB1 N-terminus RAB3GAP2_N PF14655.6 KDO23995.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-B_box PF00643.24 KDO23996.1 - 0.00039 20.5 25.5 0.053 13.7 10.5 2.3 2 0 0 2 2 2 2 B-box zinc finger FAP PF07174.11 KDO23996.1 - 4.8 6.6 24.9 7.7 5.9 24.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) A_thal_3526 PF09713.10 KDO23997.1 - 6e-25 87.3 0.2 9.3e-25 86.6 0.2 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) QLQ PF08880.11 KDO23997.1 - 0.026 14.3 1.5 0.026 14.3 1.5 2.5 4 0 0 4 4 4 0 QLQ ECH_2 PF16113.5 KDO23997.1 - 0.1 12.1 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase LRR_8 PF13855.6 KDO23998.1 - 5e-47 157.5 43.9 3e-11 42.9 0.1 6.0 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KDO23998.1 - 2.1e-37 126.5 19.0 4.3e-07 30.1 2.3 6.2 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO23998.1 - 2.1e-12 46.9 9.4 3.1e-05 23.6 0.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KDO23998.1 - 5.3e-11 41.5 26.1 1.9 9.4 0.2 11.3 11 1 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.6 KDO23998.1 - 0.00082 19.2 17.3 47 4.4 0.0 9.1 11 0 0 11 11 11 0 Leucine Rich repeat DUF3336 PF11815.8 KDO23999.1 - 6.8e-27 93.9 0.0 1.7e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KDO23999.1 - 1.9e-21 77.2 0.6 3.3e-21 76.4 0.1 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3821 PF12863.7 KDO23999.1 - 0.062 13.2 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) DUF92 PF01940.16 KDO24000.1 - 7.4e-75 251.4 4.8 9.3e-75 251.1 4.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Aminotran_4 PF01063.19 KDO24001.1 - 6.5e-21 75.2 0.0 3.6e-20 72.8 0.0 1.9 1 1 0 1 1 1 1 Amino-transferase class IV Tfb5 PF06331.12 KDO24001.1 - 0.15 12.0 0.1 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 TPR_2 PF07719.17 KDO24002.1 - 0.012 15.6 4.1 18 5.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2917 PF11142.8 KDO24002.1 - 0.12 11.8 1.7 0.5 9.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) DUF3808 PF10300.9 KDO24002.1 - 0.12 11.1 0.6 0.36 9.5 0.0 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) CCDC53 PF10152.9 KDO24004.1 - 1.4e-25 90.5 18.9 9.6e-10 39.1 0.5 4.3 3 1 0 3 3 3 3 Subunit CCDC53 of WASH complex zf-MYND PF01753.18 KDO24004.1 - 1.6e-06 28.1 15.4 2.4e-06 27.5 15.4 1.3 1 0 0 1 1 1 1 MYND finger FAM176 PF14851.6 KDO24004.1 - 0.25 11.0 2.5 0.78 9.4 2.5 1.8 1 0 0 1 1 1 0 FAM176 family zf-C6H2 PF15801.5 KDO24004.1 - 2.6 8.4 10.5 5 7.5 10.5 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding FlaC_arch PF05377.11 KDO24004.1 - 5.4 7.5 7.1 9.8 6.7 1.1 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TRAUB PF08164.12 KDO24005.1 - 2.8e-18 66.2 0.4 2.8e-18 66.2 0.4 2.2 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KDO24005.1 - 1.5e-08 35.4 0.5 1.5e-08 35.4 0.5 3.0 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor GBP PF02263.19 KDO24005.1 - 8.4e-06 25.2 0.2 1.4e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Nop14 PF04147.12 KDO24005.1 - 0.53 8.4 20.7 0.86 7.7 20.7 1.4 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L13e PF01294.18 KDO24006.1 - 1.4e-75 253.1 3.7 1.7e-75 252.9 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Jas PF16135.5 KDO24008.1 - 0.055 13.7 1.1 0.074 13.2 0.0 1.8 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling Metallophos PF00149.28 KDO24011.1 - 6.6e-12 46.4 2.9 1.7e-11 45.0 2.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO24011.1 - 4e-08 33.6 0.4 1.1e-07 32.1 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNA_pol_Rpb1_5 PF04998.17 KDO24012.1 - 1.6e-91 306.5 0.0 2.5e-91 305.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KDO24012.1 - 4.7e-64 215.6 0.3 8.9e-64 214.7 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KDO24012.1 - 2e-28 99.3 0.0 4.8e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KDO24012.1 - 2.9e-20 72.2 0.0 6.8e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 BUD22 PF09073.10 KDO24012.1 - 0.05 13.0 15.9 0.18 11.1 14.1 2.0 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KDO24012.1 - 4.7 5.3 15.6 7.7 4.6 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family Ank_4 PF13637.6 KDO24013.1 - 2.7e-23 82.0 0.6 4.4e-11 43.1 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24013.1 - 7e-22 77.8 0.0 9.9e-15 54.9 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO24013.1 - 1e-21 76.4 1.8 1.6e-06 28.3 0.3 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KDO24013.1 - 1.3e-21 76.3 1.1 1.8e-12 47.3 0.4 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24013.1 - 6.5e-17 59.9 1.5 0.00012 22.2 0.2 4.6 4 0 0 4 4 4 3 Ankyrin repeat TAtT PF16811.5 KDO24013.1 - 0.081 12.2 0.6 0.13 11.5 0.6 1.2 1 0 0 1 1 1 0 TRAP transporter T-component Herpes_UL56 PF04534.12 KDO24013.1 - 2 7.9 4.9 3.3 7.1 4.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein HSF_DNA-bind PF00447.17 KDO24014.1 - 4.2e-25 88.2 1.9 7.6e-25 87.4 1.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding zf-RING_2 PF13639.6 KDO24015.1 - 1.8e-12 47.4 7.8 3.5e-12 46.5 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO24015.1 - 6.8e-09 35.9 9.4 2e-08 34.4 9.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO24015.1 - 2.9e-08 33.3 5.7 6.6e-08 32.2 5.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO24015.1 - 1.2e-07 31.4 8.4 2.8e-07 30.3 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO24015.1 - 2e-07 30.8 6.4 4.4e-07 29.6 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO24015.1 - 6.6e-06 25.9 3.2 6.6e-06 25.9 3.2 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO24015.1 - 9.3e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 KDO24015.1 - 1.7e-05 24.6 6.1 3.4e-05 23.7 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO24015.1 - 2.2e-05 24.4 5.3 6.2e-05 22.9 5.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO24015.1 - 7.9e-05 22.6 5.0 0.00018 21.5 5.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO24015.1 - 0.0052 16.6 5.7 0.014 15.3 5.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zinc_ribbon_16 PF17034.5 KDO24015.1 - 0.006 16.8 4.1 0.014 15.6 4.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family zf-C3HC4_4 PF15227.6 KDO24015.1 - 0.0071 16.5 2.0 0.0071 16.5 2.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KDO24015.1 - 0.013 15.1 6.1 0.034 13.8 6.1 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KDO24015.1 - 0.022 14.9 5.6 0.065 13.4 5.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Myb_DNA-bind_2 PF08914.11 KDO24015.1 - 0.036 14.3 1.2 0.062 13.5 0.7 1.6 1 1 0 1 1 1 0 Rap1 Myb domain zf-RING_4 PF14570.6 KDO24015.1 - 0.051 13.4 4.2 0.11 12.3 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KDO24015.1 - 0.12 12.5 6.5 0.4 10.8 6.5 1.9 1 1 0 1 1 1 0 RING-variant domain RecR PF02132.15 KDO24015.1 - 2.3 7.9 4.8 2.9 7.6 0.4 2.4 2 0 0 2 2 2 0 RecR protein zf-RING-like PF08746.11 KDO24015.1 - 5.3 7.4 7.1 12 6.3 7.1 1.7 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 KDO24015.1 - 6.4 6.7 6.4 2.8 7.8 3.6 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Aldedh PF00171.22 KDO24016.1 - 2.1e-123 412.3 0.5 2.5e-123 412.0 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KDO24016.1 - 0.082 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Sec7 PF01369.20 KDO24017.1 - 4e-69 232.0 0.0 1.1e-68 230.5 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KDO24017.1 - 2.5e-44 151.0 2.1 1.1e-43 148.9 2.1 2.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KDO24017.1 - 1.1e-32 111.8 0.8 1.5e-29 101.7 0.0 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) DCB PF16213.5 KDO24017.1 - 3.7e-31 108.2 2.8 3.7e-31 108.2 2.8 4.1 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KDO24017.1 - 3.2e-06 25.6 0.0 9.1e-06 24.1 0.0 1.7 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Bromodomain PF00439.25 KDO24018.1 - 1.7e-18 66.5 0.2 5.1e-18 64.9 0.1 1.9 2 0 0 2 2 2 1 Bromodomain LCE6A PF15858.5 KDO24018.1 - 0.046 14.5 0.4 0.13 13.1 0.4 1.7 1 0 0 1 1 1 0 Late cornified envelope protein 6A family ASF1_hist_chap PF04729.13 KDO24019.1 - 2.5e-69 232.1 0.0 3.1e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Methyltransf_25 PF13649.6 KDO24020.1 - 1.9e-13 51.0 0.1 1.1e-12 48.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO24020.1 - 9.6e-11 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO24020.1 - 2e-10 41.2 0.0 6.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO24020.1 - 3.1e-10 39.9 0.0 4.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KDO24020.1 - 4.5e-07 29.9 0.0 2.5e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO24020.1 - 2e-06 28.5 0.1 5e-06 27.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KDO24020.1 - 5.4e-06 25.6 0.1 7.5e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KDO24020.1 - 2.4e-05 23.8 0.0 3.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KDO24020.1 - 4.2e-05 23.5 0.1 7.2e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO24020.1 - 0.00016 21.3 0.1 0.00027 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KDO24020.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KDO24020.1 - 0.004 16.5 0.1 0.0074 15.6 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase domain PRMT5_C PF17286.2 KDO24020.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain FtsJ PF01728.19 KDO24020.1 - 0.021 14.9 0.0 0.045 13.9 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KDO24020.1 - 0.028 15.4 0.0 0.054 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KDO24020.1 - 0.039 13.8 0.1 0.084 12.7 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TehB PF03848.14 KDO24020.1 - 0.045 13.2 0.4 0.18 11.2 0.4 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 KDO24020.1 - 0.046 13.5 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KDO24020.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KDO24020.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 KDO24020.1 - 0.13 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ribosomal_L24e PF01246.20 KDO24021.1 - 6.3e-27 93.6 0.2 1.6e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e DUF775 PF05603.12 KDO24021.1 - 0.013 15.0 0.2 0.015 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) HAD_SAK_2 PF18143.1 KDO24021.1 - 0.026 14.8 0.3 0.031 14.6 0.3 1.2 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins CTP_transf_like PF01467.26 KDO24021.1 - 0.04 14.1 1.2 0.72 10.0 0.9 2.0 1 1 1 2 2 2 0 Cytidylyltransferase-like DUF2058 PF09831.9 KDO24021.1 - 2 8.5 10.7 2.9 8.0 10.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) WD40 PF00400.32 KDO24022.1 - 7e-11 42.5 8.2 0.00018 22.3 0.0 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO24022.1 - 3.4e-05 23.0 0.0 0.00011 21.3 0.0 1.8 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KDO24022.1 - 0.00028 21.1 0.0 2.7 8.4 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KDO24022.1 - 0.13 12.2 0.2 10 6.2 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EGF_2 PF07974.13 KDO24023.1 - 6.7e-24 84.0 106.9 4.4e-07 30.1 3.7 9.5 9 0 0 9 9 9 9 EGF-like domain Laminin_EGF PF00053.24 KDO24023.1 - 2.5e-06 27.5 82.6 0.0017 18.5 4.2 7.8 7 2 0 7 7 7 7 Laminin EGF domain EGF PF00008.27 KDO24023.1 - 0.00095 19.4 17.0 0.0049 17.1 7.8 10.4 11 0 0 11 11 11 5 EGF-like domain PAP2_C PF14360.6 KDO24024.1 - 6.5e-12 45.8 6.7 6.5e-12 45.8 6.7 2.8 4 0 0 4 4 4 1 PAP2 superfamily C-terminal YrhC PF14143.6 KDO24024.1 - 1.5 9.0 7.8 0.14 12.3 1.1 2.3 2 0 0 2 2 2 0 YrhC-like protein ABC2_membrane PF01061.24 KDO24025.1 - 5e-32 111.0 23.9 5e-32 111.0 23.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KDO24025.1 - 1.7e-29 103.1 0.1 2.9e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO24025.1 - 5.7e-12 46.0 0.1 3.8e-06 26.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO24025.1 - 1.3e-05 24.8 0.1 0.063 12.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KDO24025.1 - 2.6e-05 23.9 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KDO24025.1 - 0.00017 21.3 0.1 0.00052 19.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO24025.1 - 0.00054 20.4 0.1 0.0011 19.4 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KDO24025.1 - 0.00074 19.5 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KDO24025.1 - 0.0022 18.5 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 KDO24025.1 - 0.0031 16.7 24.5 0.0055 15.9 24.5 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 KDO24025.1 - 0.0037 17.5 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO24025.1 - 0.0058 15.7 0.1 0.039 13.0 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein PDR_CDR PF06422.12 KDO24025.1 - 0.0072 16.2 0.2 0.0072 16.2 0.2 2.8 2 1 1 3 3 3 1 CDR ABC transporter NACHT PF05729.12 KDO24025.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KDO24025.1 - 0.022 15.3 0.0 0.04 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KDO24025.1 - 0.032 12.9 0.1 0.72 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KDO24025.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KDO24025.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KDO24025.1 - 0.048 13.4 0.4 0.14 11.8 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO24025.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 KDO24025.1 - 0.064 12.9 0.1 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 KDO24025.1 - 0.14 12.6 0.0 0.5 10.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KDO24025.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Aminotran_5 PF00266.19 KDO24026.1 - 1.1e-36 126.6 0.0 6.1e-26 91.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KDO24026.1 - 0.00048 19.4 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Arfaptin PF06456.13 KDO24027.1 - 0.056 13.0 0.7 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Arfaptin-like domain Syntaxin-6_N PF09177.11 KDO24027.1 - 0.63 10.6 3.2 5.8 7.5 0.3 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4246 PF14033.6 KDO24028.1 - 5.6e-34 118.0 0.0 8.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ank_2 PF12796.7 KDO24028.1 - 5.3e-20 71.8 3.5 6.3e-09 36.3 0.5 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24028.1 - 1.5e-17 63.7 2.1 1.8e-05 25.2 0.1 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24028.1 - 1.2e-14 54.1 8.9 4.7e-06 26.8 0.3 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24028.1 - 4.8e-12 45.0 5.6 0.0015 18.8 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 KDO24028.1 - 5.6e-09 36.0 24.4 0.002 18.5 0.2 6.6 6 2 0 6 6 6 4 Ankyrin repeat Cmc1 PF08583.10 KDO24029.1 - 2.8e-14 52.9 1.0 2.8e-14 52.9 1.0 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KDO24029.1 - 0.028 14.7 0.4 0.034 14.4 0.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Trehalase PF01204.18 KDO24029.1 - 0.067 12.0 0.1 0.075 11.8 0.1 1.0 1 0 0 1 1 1 0 Trehalase CHCH PF06747.13 KDO24029.1 - 0.098 12.8 0.9 0.21 11.8 0.9 1.7 1 0 0 1 1 1 0 CHCH domain RES PF08808.11 KDO24029.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 RES domain WD40 PF00400.32 KDO24030.1 - 2.6e-25 88.2 18.4 3.3e-05 24.6 0.2 6.1 4 1 2 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO24030.1 - 1.1e-06 28.8 0.1 0.1 12.9 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L40e PF01020.17 KDO24031.1 - 4.8e-29 100.0 10.7 5.3e-29 99.9 10.7 1.0 1 0 0 1 1 1 1 Ribosomal L40e family Complex1_LYR PF05347.15 KDO24032.1 - 4.9e-09 36.1 0.3 6.4e-09 35.7 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) FtsA PF14450.6 KDO24032.1 - 0.097 13.1 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Cell division protein FtsA S1 PF00575.23 KDO24033.1 - 2.7e-07 30.8 0.1 6e-07 29.7 0.1 1.5 2 0 0 2 2 2 1 S1 RNA binding domain MSA-2c PF12238.8 KDO24034.1 - 2.7 8.0 0.0 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Merozoite surface antigen 2c tRNA-synt_His PF13393.6 KDO24036.1 - 1.2e-43 149.6 0.0 2e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 KDO24036.1 - 3.5e-13 49.9 0.0 4.9e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KDO24036.1 - 1.8e-10 40.8 0.0 3.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 KDO24036.1 - 0.00026 20.6 0.1 0.00058 19.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) MukB PF04310.12 KDO24036.1 - 0.13 12.0 0.1 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 MukB N-terminal SET PF00856.28 KDO24037.1 - 3.1e-12 47.2 0.0 4.4e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 KDO24037.1 - 0.041 13.8 1.6 0.043 13.7 0.3 1.7 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KDO24037.1 - 0.13 12.1 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 F-box domain GST_C_3 PF14497.6 KDO24038.1 - 9.3e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO24038.1 - 0.006 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF998 PF06197.13 KDO24038.1 - 0.092 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Ribosomal_L19e PF01280.20 KDO24039.1 - 2.6e-64 215.6 11.0 2.6e-64 215.6 11.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e MCM PF00493.23 KDO24044.1 - 1.4e-98 328.5 0.1 2.1e-98 327.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KDO24044.1 - 1.1e-36 125.5 1.6 2.3e-36 124.4 1.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KDO24044.1 - 7.3e-27 93.6 0.8 7.3e-27 93.6 0.8 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KDO24044.1 - 1.8e-12 47.8 0.0 6.6e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KDO24044.1 - 7.6e-05 22.2 0.0 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KDO24044.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KDO24044.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L27A PF00828.19 KDO24045.1 - 1.1e-37 129.6 0.2 1.7e-37 129.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Colicin_V PF02674.16 KDO24046.1 - 0.047 13.6 8.2 0.017 15.1 5.7 1.5 2 0 0 2 2 2 0 Colicin V production protein LptF_LptG PF03739.14 KDO24046.1 - 0.17 10.7 5.5 0.32 9.8 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG PRA1 PF03208.19 KDO24046.1 - 2.3 7.8 8.9 0.83 9.3 6.6 1.4 2 0 0 2 2 2 0 PRA1 family protein DUF4148 PF13663.6 KDO24046.1 - 2.5 8.4 7.1 0.64 10.3 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4148) DUF1772 PF08592.11 KDO24046.1 - 4.4 7.6 9.2 21 5.4 9.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Myb_DNA-bind_6 PF13921.6 KDO24048.1 - 0.005 17.1 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain AP-5_subunit_s1 PF15001.6 KDO24049.1 - 0.14 12.2 4.6 0.14 12.1 4.6 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 RNase_PH PF01138.21 KDO24052.1 - 6.6e-26 91.4 0.0 1e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO24052.1 - 0.0035 17.3 0.1 0.0074 16.3 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cytochrom_C1 PF02167.15 KDO24053.1 - 8.9e-96 319.8 0.0 1.1e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KDO24053.1 - 0.00096 19.4 0.2 0.0029 17.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KDO24053.1 - 0.024 15.8 0.2 0.062 14.4 0.2 1.8 1 1 0 1 1 1 0 Cytochrome c LIAS_N PF16881.5 KDO24055.1 - 6.8e-11 42.5 0.1 1.7e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KDO24055.1 - 2.3e-09 37.9 0.0 7.8e-09 36.1 0.0 1.9 1 1 1 2 2 2 2 Radical SAM superfamily PRK PF00485.18 KDO24056.1 - 1.5e-37 129.2 0.0 2.1e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KDO24056.1 - 2.6e-06 28.0 0.0 4.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO24056.1 - 6.7e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO24056.1 - 0.00084 18.5 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.6 KDO24056.1 - 0.008 16.6 0.9 0.098 13.1 0.9 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KDO24056.1 - 0.0092 16.5 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 KDO24056.1 - 0.012 15.7 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain CoaE PF01121.20 KDO24056.1 - 0.017 14.8 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_28 PF13521.6 KDO24056.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KDO24056.1 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KDO24056.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 KDO24056.1 - 0.033 13.9 0.2 0.42 10.3 0.0 2.1 1 1 1 2 2 2 0 Cytidylate kinase ATPase_2 PF01637.18 KDO24056.1 - 0.047 13.6 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 KDO24056.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KDO24056.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KDO24056.1 - 0.058 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KDO24056.1 - 0.059 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 KDO24056.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 RNA helicase dNK PF01712.19 KDO24056.1 - 0.083 12.7 0.0 10 5.9 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 KDO24056.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO24056.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO24056.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KDO24056.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 NTPase Tubulin_2 PF13809.6 KDO24056.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like AAA_23 PF13476.6 KDO24056.1 - 0.37 11.3 0.8 0.61 10.6 0.8 1.2 1 0 0 1 1 1 0 AAA domain DUF2046 PF09755.9 KDO24058.1 - 0.062 12.5 1.2 0.1 11.8 1.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF3410 PF11890.8 KDO24061.1 - 0.0055 16.5 0.3 0.088 12.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3410) betaPIX_CC PF16523.5 KDO24061.1 - 0.047 13.5 0.2 7.7 6.4 0.0 2.6 2 0 0 2 2 2 0 betaPIX coiled coil Pox_A_type_inc PF04508.12 KDO24069.1 - 0.87 9.5 2.8 5.3 7.1 0.3 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Csm1_N PF18504.1 KDO24072.1 - 0.0042 17.4 0.1 0.69 10.3 0.0 2.8 2 0 0 2 2 2 2 Csm1 N-terminal domain PMSR PF01625.21 KDO24073.1 - 1e-61 207.6 0.3 1.3e-61 207.3 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CAF1 PF04857.20 KDO24073.1 - 0.048 12.8 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease SAP PF02037.27 KDO24075.1 - 1.1e-05 25.0 1.8 3e-05 23.7 1.8 1.8 1 0 0 1 1 1 1 SAP domain DUF778 PF05608.12 KDO24075.1 - 2.4 8.5 4.7 8.3 6.7 4.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF778) CDC45 PF02724.14 KDO24075.1 - 7.1 4.8 12.2 12 4.1 12.2 1.4 1 0 0 1 1 1 0 CDC45-like protein INCENP_ARK-bind PF03941.15 KDO24076.1 - 1.2e-10 41.2 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ING PF12998.7 KDO24077.1 - 1.6e-20 73.5 4.0 8.9e-20 71.2 2.0 2.5 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KDO24077.1 - 5.7e-05 22.9 9.5 9.4e-05 22.2 9.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KDO24077.1 - 0.031 13.8 2.9 0.066 12.8 2.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KDO24077.1 - 0.067 13.4 2.3 0.18 12.1 2.3 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain TRAPP PF04051.16 KDO24078.1 - 1.1e-35 122.5 0.0 1.3e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HlyE PF06109.13 KDO24079.1 - 0.0031 16.9 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Haemolysin E (HlyE) DUF2729 PF10870.8 KDO24080.1 - 0.15 12.0 0.1 0.51 10.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) RasGAP_C PF03836.15 KDO24080.1 - 0.2 11.8 0.4 0.41 10.8 0.4 1.4 1 0 0 1 1 1 0 RasGAP C-terminus NDK PF00334.19 KDO24081.1 - 1.2e-53 180.7 0.0 1.4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NPL4 PF05021.15 KDO24082.1 - 4.4e-21 75.5 0.0 1.4e-19 70.6 0.0 2.9 2 1 0 2 2 2 1 NPL4 family UN_NPL4 PF11543.8 KDO24082.1 - 4.8e-07 30.2 0.0 9.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Peptidase_C1 PF00112.23 KDO24084.1 - 1.5e-54 185.4 6.4 1.9e-54 185.0 6.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO24084.1 - 0.001 17.9 0.7 0.002 17.0 0.2 1.6 2 0 0 2 2 2 1 Peptidase C1-like family LRR_6 PF13516.6 KDO24086.1 - 2 8.7 6.4 49 4.4 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich repeat AAA PF00004.29 KDO24087.1 - 5e-43 146.7 0.0 1e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KDO24087.1 - 2.9e-22 78.5 0.4 2.9e-22 78.5 0.4 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 KDO24087.1 - 4e-13 49.2 0.0 1.8e-12 47.0 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KDO24087.1 - 7.2e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO24087.1 - 2.6e-05 24.3 0.0 0.00012 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO24087.1 - 2.7e-05 24.6 0.1 0.0018 18.7 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 KDO24087.1 - 3e-05 23.7 0.3 0.00024 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain IstB_IS21 PF01695.17 KDO24087.1 - 3.8e-05 23.5 0.0 0.0001 22.1 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO24087.1 - 9.5e-05 22.7 0.1 0.0059 16.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KDO24087.1 - 0.00012 22.1 0.0 0.00048 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KDO24087.1 - 0.00026 20.8 0.2 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO24087.1 - 0.0003 20.0 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 KDO24087.1 - 0.00051 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KDO24087.1 - 0.00088 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KDO24087.1 - 0.0014 19.2 0.0 0.0039 17.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KDO24087.1 - 0.0019 18.6 0.0 0.0053 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KDO24087.1 - 0.0025 18.0 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KDO24087.1 - 0.0048 16.0 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATPase PF06745.13 KDO24087.1 - 0.0082 15.5 0.1 2.2 7.6 0.0 2.4 1 1 1 2 2 2 1 KaiC AAA_17 PF13207.6 KDO24087.1 - 0.0093 16.4 0.1 0.027 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO24087.1 - 0.015 14.9 0.1 0.66 9.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KDO24087.1 - 0.033 13.6 0.0 0.089 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KDO24087.1 - 0.036 13.6 0.0 0.087 12.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KDO24087.1 - 0.071 12.4 0.1 1.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KDO24087.1 - 0.08 12.8 0.7 1.9 8.3 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KDO24087.1 - 0.084 12.8 0.0 0.85 9.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 KDO24087.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AFG1_ATPase PF03969.16 KDO24087.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Torsin PF06309.11 KDO24087.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 KDO24087.1 - 0.16 11.6 0.0 0.75 9.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Zn_ribbon_SprT PF17283.2 KDO24091.1 - 0.012 15.5 0.8 0.021 14.7 0.8 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Exo_endo_phos PF03372.23 KDO24092.1 - 2.3e-10 40.4 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OAD_gamma PF04277.13 KDO24092.1 - 0.17 12.5 0.1 0.32 11.6 0.1 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain THOC2_N PF16134.5 KDO24093.1 - 0.11 11.1 10.5 0.15 10.7 10.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Rsa3 PF14615.6 KDO24093.1 - 0.15 11.7 0.3 0.27 10.8 0.1 1.6 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF2052 PF09747.9 KDO24093.1 - 0.2 11.8 11.2 0.23 11.5 11.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4551 PF15087.6 KDO24093.1 - 0.58 8.9 11.8 0.6 8.9 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NifU_N PF01592.16 KDO24095.1 - 1.7e-55 186.6 0.3 2.1e-55 186.3 0.3 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain GLTP PF08718.11 KDO24096.1 - 2e-21 76.8 0.0 3.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) FYVE PF01363.21 KDO24096.1 - 4.1e-09 36.4 11.7 7.3e-09 35.6 11.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO24096.1 - 0.01 16.0 4.0 0.024 14.9 4.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KDO24096.1 - 0.045 13.9 5.4 0.12 12.5 5.4 1.7 1 0 0 1 1 1 0 B-box zinc finger DUF2786 PF10979.8 KDO24096.1 - 0.1 12.5 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) PocR PF10114.9 KDO24096.1 - 0.1 12.4 1.4 0.19 11.5 1.4 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR zf-piccolo PF05715.13 KDO24096.1 - 0.78 9.9 6.3 2 8.7 6.3 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger PTPLA PF04387.14 KDO24097.1 - 4.9e-57 192.3 10.5 6.6e-57 191.8 10.5 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Rad60-SLD PF11976.8 KDO24098.1 - 2.3e-09 36.9 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KDO24098.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TmoB PF06234.12 KDO24098.1 - 0.056 13.5 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) AcMNPV_Ac109 PF05054.12 KDO24098.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein MFS_1 PF07690.16 KDO24099.1 - 8e-12 44.7 51.9 3.7e-07 29.4 12.9 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Y_phosphatase2 PF03162.13 KDO24100.1 - 2.2e-48 163.9 0.0 2.6e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KDO24100.1 - 3.7e-05 23.8 0.0 5.5e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Rad60-SLD PF11976.8 KDO24101.1 - 1.7e-17 63.0 0.1 2.1e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KDO24101.1 - 3.5e-10 39.5 0.0 4.1e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family bZIP_1 PF00170.21 KDO24103.1 - 3.3e-07 30.3 6.2 7.5e-07 29.1 6.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO24103.1 - 0.0093 16.0 7.7 0.022 14.8 7.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper HAUS4 PF14735.6 KDO24103.1 - 0.011 15.5 0.6 0.025 14.3 0.6 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Alg14 PF08660.11 KDO24104.1 - 1.9e-62 210.3 0.0 2.2e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ribosomal_S19e PF01090.19 KDO24105.1 - 5.3e-54 181.6 0.1 5.9e-54 181.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Nop PF01798.18 KDO24106.1 - 4.6e-84 281.5 0.0 4.6e-84 281.5 0.0 2.3 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KDO24106.1 - 3.7e-19 68.8 1.8 3.7e-19 68.8 1.8 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KDO24106.1 - 1.2 9.2 36.7 2.2 8.3 36.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KDO24106.1 - 3.9 7.2 18.8 6.5 6.5 18.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tmemb_185A PF10269.9 KDO24107.1 - 2.1e-07 30.9 24.1 0.0019 18.0 8.7 3.0 1 1 0 2 2 2 2 Transmembrane Fragile-X-F protein RseC_MucC PF04246.12 KDO24107.1 - 1.9 8.4 7.6 0.34 10.8 3.0 2.1 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Tmemb_185A PF10269.9 KDO24108.1 - 2.9e-06 27.1 29.9 0.00049 19.9 1.3 3.8 1 1 0 3 3 3 3 Transmembrane Fragile-X-F protein HTH_Tnp_Tc5 PF03221.16 KDO24109.1 - 3.3e-09 36.7 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 KDO24109.1 - 6.8e-06 25.5 0.1 1.9e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.13 KDO24109.1 - 0.00072 19.1 2.4 0.00079 19.0 1.0 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KDO24109.1 - 0.00085 19.1 0.4 0.013 15.3 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain UPF0122 PF04297.14 KDO24109.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_11 PF08279.12 KDO24109.1 - 0.08 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 KDO24109.1 - 0.087 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KDO24109.1 - 0.11 12.6 2.9 0.96 9.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 KDO24109.1 - 0.25 11.4 1.2 4.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn helix Tmemb_185A PF10269.9 KDO24110.1 - 1.7e-11 44.3 24.0 4.6e-07 29.8 6.6 3.1 2 1 1 3 3 3 3 Transmembrane Fragile-X-F protein Tmemb_185A PF10269.9 KDO24111.1 - 0.0053 16.5 26.7 0.033 13.9 1.5 3.2 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein DUF4173 PF13777.6 KDO24111.1 - 0.16 11.4 11.7 0.049 13.1 1.3 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4173) PKD_channel PF08016.12 KDO24112.1 - 4.4e-10 38.8 5.3 6.3e-10 38.3 4.6 1.5 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KDO24112.1 - 3.1e-08 33.2 8.9 5.6e-08 32.3 8.9 1.6 1 1 0 1 1 1 1 Ion transport protein DUF2157 PF09925.9 KDO24112.1 - 2.6 7.8 13.1 0.31 10.8 0.1 3.1 2 2 1 3 3 3 0 Predicted membrane protein (DUF2157) PRKG1_interact PF15898.5 KDO24113.1 - 0.72 10.8 8.5 0.2 12.6 1.3 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 KDO24113.1 - 2.8 8.6 9.7 3.3 8.4 1.6 3.1 2 2 0 2 2 2 0 SlyX Tmemb_185A PF10269.9 KDO24114.1 - 2.1e-06 27.6 1.6 2.1e-06 27.6 1.6 3.1 3 1 0 3 3 3 2 Transmembrane Fragile-X-F protein Tmemb_185A PF10269.9 KDO24115.1 - 0.0025 17.5 2.0 0.0025 17.5 2.0 2.2 1 1 1 2 2 2 1 Transmembrane Fragile-X-F protein Spore_YtrH PF14034.6 KDO24115.1 - 1.2 9.4 4.5 0.69 10.1 0.4 2.3 3 0 0 3 3 3 0 Sporulation protein YtrH Cytochrome-c551 PF10643.9 KDO24115.1 - 2.7 7.5 10.9 0.48 10.0 3.2 2.1 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Saf_2TM PF18303.1 KDO24117.1 - 0.0041 16.7 0.2 0.46 10.1 0.0 2.3 2 0 0 2 2 2 2 SAVED-fused 2TM effector domain DNA_pol_phi PF04931.13 KDO24118.1 - 7e-111 371.7 43.2 3.9e-106 356.0 32.4 3.6 2 1 1 3 3 3 2 DNA polymerase phi BUD22 PF09073.10 KDO24118.1 - 0.12 11.7 11.9 0.28 10.5 11.9 1.6 1 0 0 1 1 1 0 BUD22 Rrp44_CSD1 PF17216.3 KDO24118.1 - 0.48 10.1 1.9 1.4 8.6 1.9 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain NDUF_C2 PF06374.11 KDO24119.1 - 0.012 15.7 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Gly-zipper_Omp PF13488.6 KDO24119.1 - 0.021 14.8 1.7 1.5 8.9 0.1 2.1 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KDO24119.1 - 0.027 14.3 0.2 2 8.3 0.2 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KDO24119.1 - 0.061 13.1 2.2 0.6 9.9 2.8 1.9 1 1 1 2 2 2 0 YMGG-like Gly-zipper ATPase_gene1 PF09527.10 KDO24119.1 - 0.1 12.8 0.8 3 8.1 0.0 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF998 PF06197.13 KDO24120.1 - 0.02 14.5 16.6 0.83 9.2 4.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Caskin1-CID PF16600.5 KDO24120.1 - 0.048 14.2 2.3 0.11 13.1 2.3 1.5 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain PH PF00169.29 KDO24121.1 - 5.3e-08 33.3 0.0 1.3e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 PH domain PIG-L PF02585.17 KDO24122.1 - 7.4e-22 78.4 0.6 1.1e-21 77.9 0.6 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase GAS PF13851.6 KDO24123.1 - 0.0083 15.5 11.8 0.0083 15.5 11.8 3.5 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding FKBP_C PF00254.28 KDO24123.1 - 0.16 12.3 0.0 0.53 10.6 0.0 1.8 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase PI_PP_I PF18363.1 KDO24123.1 - 2.4 8.4 4.5 45 4.3 0.3 3.3 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain Ion_trans PF00520.31 KDO24124.1 - 4.2e-08 32.7 8.7 4.2e-08 32.7 8.7 2.3 2 0 0 2 2 2 1 Ion transport protein DUF1230 PF06799.11 KDO24124.1 - 0.61 10.2 6.5 0.14 12.3 1.3 2.5 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 PKD_channel PF08016.12 KDO24125.1 - 3.6e-09 35.8 2.3 3.6e-09 35.8 2.3 1.9 1 1 0 1 1 1 1 Polycystin cation channel ATG16 PF08614.11 KDO24125.1 - 0.027 14.7 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF5392 PF17370.2 KDO24125.1 - 0.053 13.6 0.4 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5392) SlyX PF04102.12 KDO24125.1 - 0.12 13.0 1.0 0.25 12.0 1.0 1.5 1 0 0 1 1 1 0 SlyX Cnn_1N PF07989.11 KDO24125.1 - 0.14 12.4 0.6 0.37 11.0 0.6 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF2970 PF11174.8 KDO24125.1 - 6.8 6.6 7.5 9.8 6.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) MAF_flag10 PF01973.18 KDO24126.1 - 0.045 13.4 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF115 IPTL-CTERM PF18203.1 KDO24128.1 - 0.015 15.2 1.3 0.015 15.2 1.3 3.1 3 0 0 3 3 3 0 IPTL-CTERM motif DUF4231 PF14015.6 KDO24128.1 - 0.072 13.6 0.6 0.072 13.6 0.6 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF4131 PF13567.6 KDO24128.1 - 5.6 6.6 14.7 0.89 9.2 5.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tmemb_185A PF10269.9 KDO24130.1 - 2.3e-05 24.2 14.0 0.0016 18.1 2.2 2.3 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF5472 PF17566.2 KDO24130.1 - 7.1 6.7 5.8 6.1 6.9 2.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5472) Lipase_GDSL_2 PF13472.6 KDO24132.1 - 0.16 12.3 0.4 1.8 8.9 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Ion_trans PF00520.31 KDO24133.1 - 9.1e-21 74.2 20.3 1.5e-20 73.4 20.3 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO24133.1 - 9e-12 44.8 4.5 9e-12 44.8 4.5 2.5 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 KDO24133.1 - 0.00032 20.7 0.0 0.00089 19.3 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Beach PF02138.18 KDO24135.1 - 6.6e-105 350.4 0.0 1.1e-104 349.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 KDO24135.1 - 1.6e-28 99.7 0.0 4.6e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 KDO24135.1 - 1.7e-10 40.9 0.0 4.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KDO24135.1 - 2.6e-06 27.7 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KDO24135.1 - 1.5e-05 25.6 0.7 0.0018 19.1 0.3 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4800 PF16057.5 KDO24135.1 - 6.7e-05 22.3 5.5 0.00012 21.4 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF1088 PF06469.11 KDO24135.1 - 0.026 14.2 2.3 0.048 13.3 2.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) NAD_binding_6 PF08030.12 KDO24136.1 - 3.1e-10 40.4 0.0 3.4e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KDO24136.1 - 3.6e-10 40.0 10.2 3.6e-10 40.0 10.2 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component DOMON PF03351.17 KDO24136.1 - 3.5e-09 36.9 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 DOMON domain FAD_binding_8 PF08022.12 KDO24136.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KDO24136.1 - 4e-07 30.7 0.0 7.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 KDO24136.1 - 0.013 16.0 6.4 0.013 16.0 6.4 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) SHE3 PF17078.5 KDO24137.1 - 0.00015 21.6 19.8 0.002 17.9 10.0 2.2 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 KDO24137.1 - 0.00047 20.2 10.5 0.00047 20.2 10.5 3.5 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YpsA PF06908.11 KDO24137.1 - 0.034 14.1 0.9 0.13 12.2 0.0 2.4 2 2 0 2 2 2 0 YspA SLOG family DUF3584 PF12128.8 KDO24137.1 - 0.071 10.6 39.3 0.0035 15.0 25.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) SlyX PF04102.12 KDO24137.1 - 0.071 13.7 1.3 0.071 13.7 1.3 5.2 2 2 3 5 5 5 0 SlyX HALZ PF02183.18 KDO24137.1 - 0.091 13.0 3.4 0.45 10.8 0.3 3.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper Tn7_Tnp_TnsA_C PF08721.11 KDO24137.1 - 0.29 11.8 4.2 5.3 7.8 0.1 3.4 3 0 0 3 3 3 0 TnsA endonuclease C terminal DUF1664 PF07889.12 KDO24137.1 - 0.33 11.0 19.2 0.52 10.4 2.9 3.4 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KDO24137.1 - 0.79 8.3 28.8 0.022 13.4 15.4 2.2 1 1 1 2 2 2 0 AAA domain DUF2756 PF10956.8 KDO24137.1 - 9.8 6.7 8.4 11 6.6 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2756) DHFR_1 PF00186.19 KDO24138.1 - 1.2e-36 125.8 0.0 1.4e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Ferric_reduct PF01794.19 KDO24139.1 - 8.6e-38 129.3 52.5 4.7e-14 52.6 6.9 5.3 4 0 0 4 4 4 4 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KDO24139.1 - 1.3e-26 92.8 0.1 3.2e-09 36.8 0.0 3.5 3 0 0 3 3 3 3 FAD-binding domain NAD_binding_6 PF08030.12 KDO24139.1 - 2.6e-21 76.4 0.0 7.6e-08 32.6 0.0 4.4 2 2 0 2 2 2 2 Ferric reductase NAD binding domain DOMON PF03351.17 KDO24139.1 - 1.7e-16 60.6 0.0 5.7e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 DOMON domain NAD_binding_1 PF00175.21 KDO24139.1 - 6.6e-12 46.0 0.0 7.9e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain CLZ PF16526.5 KDO24140.1 - 0.029 14.7 0.8 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 KDO24140.1 - 0.81 9.8 6.7 0.2 11.8 3.5 1.6 2 0 0 2 2 2 0 bZIP transcription factor HCMV_UL139 PF12507.8 KDO24141.1 - 0.0011 19.4 0.2 0.0018 18.6 0.2 1.3 1 0 0 1 1 1 1 Human Cytomegalovirus UL139 protein MID_pPIWI_RE PF18157.1 KDO24141.1 - 0.063 13.6 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 MID domain of pPIWI_RE Myosin_tail_1 PF01576.19 KDO24141.1 - 0.17 9.7 1.0 0.22 9.3 1.0 1.0 1 0 0 1 1 1 0 Myosin tail Ank_4 PF13637.6 KDO24143.1 - 2.3e-10 40.8 7.2 0.00067 20.2 0.3 4.2 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24143.1 - 1.2e-08 35.4 5.3 0.00028 21.4 2.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO24143.1 - 1.4e-07 31.2 0.5 3.5 8.5 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KDO24143.1 - 6.4e-06 26.4 2.8 0.012 15.9 0.4 3.4 1 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO24143.1 - 0.00066 20.0 3.9 2.7 8.6 0.1 4.3 2 2 0 2 2 2 2 Ankyrin repeat Kelch_1 PF01344.25 KDO24144.1 - 2.5e-46 155.0 9.3 6.9e-10 38.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KDO24144.1 - 4.2e-43 144.3 11.3 3.5e-08 33.4 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KDO24144.1 - 4.6e-39 132.0 15.2 2.8e-06 27.5 0.1 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO24144.1 - 4.8e-39 131.8 10.7 2.1e-07 30.7 0.1 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 KDO24144.1 - 5.3e-36 122.4 17.8 4.2e-08 33.1 0.2 6.5 5 2 2 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KDO24144.1 - 2.8e-29 99.9 10.3 4.1e-06 26.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif MFS_1 PF07690.16 KDO24145.1 - 3.9e-18 65.5 30.6 3.9e-18 65.5 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KDO24145.1 - 1.3e-10 41.2 6.2 1.3e-10 41.2 6.2 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 bZIP_1 PF00170.21 KDO24146.1 - 0.072 13.2 2.9 0.15 12.1 2.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor CRAL_TRIO PF00650.20 KDO24147.1 - 2.6e-33 115.0 0.2 3.5e-33 114.6 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KDO24147.1 - 0.0017 18.5 0.1 0.0029 17.8 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Misat_Tub_SegII PF10644.9 KDO24147.1 - 0.02 15.2 0.0 0.055 13.8 0.0 1.7 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain YEATS PF03366.16 KDO24147.1 - 0.11 12.5 0.1 0.45 10.5 0.0 2.0 1 1 1 2 2 2 0 YEATS family PDZ_6 PF17820.1 KDO24148.1 - 2e-13 49.9 0.1 0.028 14.3 0.0 4.7 5 0 0 5 5 5 4 PDZ domain PDZ PF00595.24 KDO24148.1 - 2.7e-10 40.4 0.0 0.21 12.0 0.0 5.6 5 0 0 5 5 5 4 PDZ domain PDZ_2 PF13180.6 KDO24148.1 - 2.6e-05 24.4 0.4 0.035 14.4 0.0 3.9 5 0 0 5 5 5 2 PDZ domain Solute_trans_a PF03619.16 KDO24149.1 - 7.1e-79 265.1 16.5 9e-79 264.7 16.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 KDO24150.1 - 7.5e-49 166.6 13.2 8.9e-49 166.4 13.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 KDO24151.1 - 3.6e-79 266.0 19.4 4.1e-79 265.8 19.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AFT PF08731.11 KDO24152.1 - 0.0023 18.3 0.5 0.0023 18.3 0.5 2.2 2 0 0 2 2 2 1 Transcription factor AFT FAR1 PF03101.15 KDO24152.1 - 0.14 12.9 1.6 0.84 10.4 1.6 2.4 1 1 0 1 1 1 0 FAR1 DNA-binding domain Polysacc_deac_1 PF01522.21 KDO24153.1 - 7.9e-20 71.0 0.0 1.8e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KDO24153.1 - 0.014 14.6 0.0 0.47 9.6 0.0 2.2 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase Cofilin_ADF PF00241.20 KDO24154.1 - 5.5e-36 123.0 0.0 6.1e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GDI PF00996.18 KDO24155.1 - 2.2e-199 662.4 0.0 2.6e-199 662.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KDO24155.1 - 0.085 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CCSAP PF15748.5 KDO24156.1 - 0.17 12.0 22.2 0.22 11.7 22.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Radical_SAM_N PF08497.10 KDO24156.1 - 0.17 11.1 4.8 0.23 10.7 4.8 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal TFIIA PF03153.13 KDO24156.1 - 0.18 11.8 43.0 0.2 11.6 43.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KDO24156.1 - 0.21 10.1 11.8 0.23 10.0 11.8 1.0 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 KDO24156.1 - 0.29 9.3 32.6 0.33 9.2 32.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 KDO24156.1 - 0.62 9.8 13.8 0.73 9.6 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 2OG-FeII_Oxy_5 PF13759.6 KDO24156.1 - 0.93 9.9 11.9 2.2 8.7 11.9 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Presenilin PF01080.17 KDO24156.1 - 1.2 7.9 19.3 1.3 7.7 19.3 1.1 1 0 0 1 1 1 0 Presenilin DUF1387 PF07139.11 KDO24156.1 - 2.2 8.0 15.8 2.5 7.8 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GREB1 PF15782.5 KDO24156.1 - 2.3 5.2 17.3 2.4 5.2 17.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 KDO24156.1 - 2.5 6.8 10.7 2.9 6.6 10.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Band_3_cyto PF07565.13 KDO24156.1 - 4.8 6.9 12.0 5.6 6.7 12.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 KDO24156.1 - 6.6 5.6 19.3 8.3 5.3 19.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 KDO24156.1 - 8.9 6.3 11.7 13 5.7 11.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Endostatin PF06482.11 KDO24156.1 - 9 5.6 18.7 12 5.3 18.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 KDO24156.1 - 9.5 5.1 15.8 11 4.9 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 YqaJ PF09588.10 KDO24157.1 - 0.012 15.8 0.3 0.072 13.2 0.3 2.2 1 1 0 1 1 1 0 YqaJ-like viral recombinase domain DUF4058 PF13267.6 KDO24157.1 - 0.018 14.5 0.7 0.03 13.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Kinesin PF00225.23 KDO24158.1 - 5.3e-96 321.4 0.1 5.3e-96 321.4 0.1 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO24158.1 - 3e-48 163.5 0.0 1.2e-47 161.6 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Snapin_Pallidin PF14712.6 KDO24158.1 - 0.013 15.9 2.2 0.013 15.9 2.2 4.1 3 1 1 4 4 4 0 Snapin/Pallidin BCL9 PF11502.8 KDO24158.1 - 0.099 12.5 0.2 0.28 11.0 0.2 1.7 1 0 0 1 1 1 0 B-cell lymphoma 9 protein YcgR PF07317.12 KDO24158.1 - 0.52 10.2 3.6 1.1 9.2 1.1 2.4 2 0 0 2 2 2 0 Flagellar regulator YcgR KxDL PF10241.9 KDO24158.1 - 1.2 9.5 9.9 2.1 8.7 3.2 3.3 2 1 0 2 2 2 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 KDO24158.1 - 9 6.3 30.7 0.58 10.2 3.8 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.7 KDO24159.1 - 2.2e-52 175.5 27.1 2e-13 50.7 1.2 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO24159.1 - 1.2e-36 124.3 17.0 1.3e-08 34.9 0.2 8.4 4 4 5 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO24159.1 - 5.9e-33 112.8 5.0 1.3e-08 35.2 0.2 8.0 5 4 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO24159.1 - 1.8e-31 107.2 24.9 0.00017 21.9 0.1 11.0 10 1 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KDO24159.1 - 3.2e-29 97.7 14.4 0.001 19.3 0.0 10.4 9 1 1 10 10 10 7 Ankyrin repeat VWA_3_C PF18571.1 KDO24159.1 - 0.012 15.4 2.2 28 4.7 0.0 5.2 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Ldi PF18566.1 KDO24159.1 - 0.027 14.0 0.1 0.15 11.5 0.1 2.0 2 0 0 2 2 2 0 Linalool dehydratase/isomerase Cyclin_N PF00134.23 KDO24159.1 - 2.2 8.0 4.0 23 4.7 0.0 3.9 4 2 1 5 5 5 0 Cyclin, N-terminal domain VWA PF00092.28 KDO24160.1 - 4.5e-10 40.1 0.0 6.9e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain GBP PF02263.19 KDO24160.1 - 3.8e-07 29.6 0.1 9.2e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KDO24160.1 - 3.1e-06 25.7 0.3 5.2e-06 24.9 0.3 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) VWA_2 PF13519.6 KDO24160.1 - 4.2e-06 27.4 0.0 5.5e-05 23.8 0.0 3.1 2 1 0 2 2 2 1 von Willebrand factor type A domain Dynamin_N PF00350.23 KDO24160.1 - 0.024 14.7 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Dynamin family Ank_4 PF13637.6 KDO24161.1 - 8e-16 58.2 1.2 1.6e-06 28.6 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24161.1 - 7.2e-15 55.3 1.8 6.5e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO24161.1 - 4.2e-13 48.2 1.4 0.0016 18.7 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO24161.1 - 1.5e-11 44.3 3.6 0.00031 21.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO24161.1 - 3.1e-09 36.9 3.4 0.0011 19.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Dynamin_N PF00350.23 KDO24163.1 - 3.8e-12 46.6 0.0 2.8e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KDO24163.1 - 2.9e-07 30.6 0.0 1e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO24163.1 - 0.00012 22.1 0.2 0.052 13.5 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase Roc PF08477.13 KDO24163.1 - 0.018 15.3 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KDO24163.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.16 KDO24163.1 - 0.054 12.8 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Septin PF00735.18 KDO24163.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KDO24163.1 - 0.085 12.4 0.1 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 KDO24163.1 - 0.1 11.8 0.2 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Aminotran_1_2 PF00155.21 KDO24164.1 - 1.3e-38 133.1 0.0 1.8e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KDO24164.1 - 9.4e-05 21.8 0.0 0.00024 20.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Urb2 PF10441.9 KDO24165.1 - 3.2e-22 79.5 0.5 3.2e-22 79.5 0.5 5.9 4 2 1 6 6 6 1 Urb2/Npa2 family NDK PF00334.19 KDO24166.1 - 4.1e-33 114.3 0.0 1.1e-27 96.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Flavodoxin_1 PF00258.25 KDO24167.1 - 6.3e-27 94.5 0.3 1.4e-26 93.4 0.1 1.7 2 0 0 2 2 2 1 Flavodoxin Radical_SAM PF04055.21 KDO24167.1 - 9.9e-26 91.1 0.1 1.8e-25 90.2 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 KDO24167.1 - 8.7e-22 77.2 0.2 2.5e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_NdrI PF07972.11 KDO24167.1 - 0.0048 17.0 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like DUF4196 PF13846.6 KDO24167.1 - 0.053 13.7 1.8 0.13 12.5 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Hydrolase PF00702.26 KDO24167.1 - 0.11 12.7 0.0 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ATP-synt_Eps PF04627.13 KDO24168.1 - 8.6e-12 44.9 0.2 1.6e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain IBR PF01485.21 KDO24169.1 - 4e-14 52.6 46.4 1.7e-07 31.4 19.0 4.2 1 1 3 4 4 4 3 IBR domain, a half RING-finger domain CEBP_ZZ PF16366.5 KDO24169.1 - 0.022 15.0 1.4 0.022 15.0 1.4 3.4 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain FYVE PF01363.21 KDO24169.1 - 0.024 14.8 10.2 0.024 14.8 10.2 3.4 3 1 0 3 3 3 0 FYVE zinc finger VPS9 PF02204.18 KDO24171.1 - 5.1e-28 97.3 0.0 1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KDO24171.1 - 0.00021 21.5 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Tektin PF03148.14 KDO24171.1 - 0.043 12.6 0.8 0.062 12.0 0.8 1.2 1 0 0 1 1 1 0 Tektin family tRNA_bind PF01588.20 KDO24172.1 - 3.6e-06 27.0 0.3 5.3e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.18 KDO24172.1 - 8.6e-06 25.0 2.6 1.2e-05 24.6 2.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others YabP PF07873.11 KDO24172.1 - 0.012 15.4 0.4 0.015 15.0 0.4 1.2 1 0 0 1 1 1 0 YabP family DUF4477 PF14780.6 KDO24173.1 - 4.4e-10 39.5 7.0 5.5e-10 39.2 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) SpoIISA_toxin PF14171.6 KDO24173.1 - 0.018 14.7 1.1 0.023 14.4 1.1 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system GAT PF03127.14 KDO24173.1 - 0.068 13.5 0.7 0.28 11.5 0.3 2.0 1 1 1 2 2 2 0 GAT domain Ank_2 PF12796.7 KDO24177.1 - 9.9e-74 244.0 26.0 1e-11 45.2 1.4 14.6 9 3 6 16 16 16 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24177.1 - 2.6e-58 193.7 30.2 4.7e-06 27.0 0.0 19.0 13 4 7 20 20 20 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24177.1 - 1.1e-45 153.0 44.1 0.0013 19.0 0.2 18.0 18 2 2 20 20 19 12 Ankyrin repeats (many copies) PARP PF00644.20 KDO24177.1 - 5.1e-42 143.7 0.0 2.7e-34 118.5 0.0 2.4 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Ank_3 PF13606.6 KDO24177.1 - 1.5e-36 120.2 36.7 0.02 15.4 0.0 21.7 25 0 0 25 25 21 10 Ankyrin repeat Ank PF00023.30 KDO24177.1 - 2.1e-32 110.2 73.8 3.1e-05 24.2 0.0 24.6 27 3 1 28 28 26 7 Ankyrin repeat WGR PF05406.15 KDO24177.1 - 1.9e-17 63.1 0.0 5.5e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 WGR domain PARP_reg PF02877.14 KDO24177.1 - 6.7e-12 45.7 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Nop14 PF04147.12 KDO24177.1 - 0.72 8.0 11.9 1.5 7.0 11.9 1.4 1 0 0 1 1 1 0 Nop14-like family CCDC106 PF15794.5 KDO24177.1 - 0.88 9.2 3.1 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4746 PF15928.5 KDO24177.1 - 3.1 7.1 6.9 7 6.0 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HEAT PF02985.22 KDO24179.1 - 4.5e-12 45.1 21.6 0.013 15.7 0.0 9.3 10 1 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 KDO24179.1 - 4.5e-11 43.0 7.4 0.0013 19.1 0.0 5.8 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KDO24179.1 - 5.9e-05 23.2 4.9 0.05 13.7 0.2 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KDO24179.1 - 0.0037 17.4 4.2 0.022 14.9 0.1 3.7 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KDO24179.1 - 0.0061 16.1 0.5 0.11 12.0 0.0 2.8 4 0 0 4 4 4 1 CLASP N terminal Tti2 PF10521.9 KDO24179.1 - 0.0085 15.7 0.3 0.51 9.8 0.0 2.8 3 0 0 3 3 3 1 Tti2 family Adaptin_N PF01602.20 KDO24179.1 - 0.28 9.7 8.3 1.8 7.0 0.1 3.0 3 1 0 4 4 4 0 Adaptin N terminal region HEAT_EZ PF13513.6 KDO24179.1 - 0.67 10.5 7.5 1.8 9.1 0.3 4.9 5 1 1 6 6 6 0 HEAT-like repeat HAUS2 PF15003.6 KDO24181.1 - 0.033 13.9 0.1 0.038 13.7 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 MCCD1 PF15707.5 KDO24181.1 - 0.11 13.0 0.0 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 DUF5068 PF16781.5 KDO24182.1 - 0.054 13.3 1.4 0.22 11.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5068) Melibiase_2_C PF17450.2 KDO24182.1 - 0.16 12.2 0.0 0.53 10.6 0.0 1.9 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain NYD-SP28 PF14772.6 KDO24183.1 - 5.7e-16 58.4 14.4 5.7e-16 58.4 14.4 5.1 2 1 3 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 KDO24183.1 - 1.9e-06 27.8 0.9 1.9e-06 27.8 0.9 3.7 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF948 PF06103.11 KDO24183.1 - 3.9 7.8 9.5 7.7 6.9 0.6 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SpoIIE PF07228.12 KDO24184.1 - 0.00056 19.9 0.2 0.1 12.5 0.0 3.1 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Glyco_transf_90 PF05686.12 KDO24185.1 - 1.4e-19 70.3 5.8 7.7e-18 64.6 5.8 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 90 MHC_II_beta PF00969.19 KDO24185.1 - 0.057 13.5 1.3 9.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain EMP70 PF02990.16 KDO24186.1 - 7.2e-159 529.8 4.5 1e-158 529.2 4.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 KDO24186.1 - 0.0035 16.3 13.0 0.0035 16.3 13.0 3.1 1 1 2 3 3 3 1 Major Facilitator Superfamily TatD_DNase PF01026.21 KDO24187.1 - 1.5e-56 191.7 0.0 1.8e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase UL41A PF17591.2 KDO24187.1 - 0.17 12.0 0.2 0.28 11.3 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL41A Lipase_3 PF01764.25 KDO24188.1 - 1.1e-09 38.3 0.1 2e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO24188.1 - 0.00032 21.4 1.9 0.00095 19.8 1.9 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family CAT PF00302.18 KDO24188.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase Esterase PF00756.20 KDO24188.1 - 0.035 13.8 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KDO24188.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ABC1 PF03109.16 KDO24189.1 - 1.2e-20 73.8 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KDO24189.1 - 4.7e-07 29.5 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KDO24189.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO24189.1 - 0.015 15.3 0.1 0.054 13.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family PhosphMutase PF10143.9 KDO24190.1 - 1.1e-50 171.9 0.0 1.5e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 KDO24190.1 - 3.3e-29 102.0 0.0 4.1e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KDO24190.1 - 3.7e-05 23.5 0.0 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KDO24190.1 - 0.0059 16.0 0.1 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Sulfatase CENP-L PF13092.6 KDO24191.1 - 1.1e-06 28.9 0.1 1.7e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HEAT PF02985.22 KDO24192.1 - 2.6e-07 30.3 9.0 0.08 13.2 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.8 KDO24192.1 - 1.3e-05 24.9 0.3 0.00082 19.0 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 KDO24192.1 - 1.4e-05 25.4 18.4 0.093 13.1 0.2 6.4 5 1 1 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO24192.1 - 0.015 15.9 0.1 0.13 12.9 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO24192.1 - 0.026 14.6 5.1 7.9 6.5 0.0 5.1 5 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KDO24192.1 - 1.4 9.8 10.8 0.12 13.1 1.0 4.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat V-SNARE_C PF12352.8 KDO24193.1 - 2.7e-12 46.8 2.2 1.2e-11 44.8 1.3 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF2968 PF11180.8 KDO24195.1 - 0.0074 15.9 0.9 0.0074 15.9 0.9 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.9 KDO24195.1 - 0.04 13.9 47.3 1.1 9.3 6.4 3.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KDO24195.1 - 0.12 12.4 19.5 0.62 10.1 3.2 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KDO24195.1 - 2.5 8.6 9.5 12 6.4 8.1 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KDO24195.1 - 7.8 6.8 11.9 13 6.1 2.3 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tmemb_14 PF03647.13 KDO24197.1 - 2.9e-20 72.8 10.0 3.5e-20 72.5 10.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KDO24197.1 - 0.0033 17.7 2.7 0.0049 17.1 2.7 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 His_Phos_2 PF00328.22 KDO24198.1 - 5.8e-79 266.2 0.1 1.8e-75 254.7 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KDO24198.1 - 7.9e-38 128.5 0.1 1.7e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KDO24198.1 - 0.005 16.5 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF3322 PF11795.8 KDO24198.1 - 0.015 15.3 0.1 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) adh_short PF00106.25 KDO24199.1 - 2.7e-16 59.6 1.9 7.7e-16 58.1 1.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO24199.1 - 5.2e-13 49.1 2.1 1e-12 48.2 1.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KDO24199.1 - 1.8e-05 24.3 0.2 4.1e-05 23.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LpxI_N PF17930.1 KDO24199.1 - 9.7e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 LpxI N-terminal domain RmlD_sub_bind PF04321.17 KDO24199.1 - 0.0025 17.0 0.1 0.0066 15.6 0.2 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 KDO24199.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KDO24199.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain B12-binding PF02310.19 KDO24199.1 - 0.032 14.3 0.2 0.092 12.8 0.2 1.8 1 1 0 1 1 1 0 B12 binding domain NAD_binding_10 PF13460.6 KDO24199.1 - 0.042 13.7 0.6 0.062 13.2 0.5 1.3 1 1 0 1 1 1 0 NAD(P)H-binding Peptidase_S66 PF02016.15 KDO24199.1 - 0.057 13.5 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain 2-Hacid_dh_C PF02826.19 KDO24199.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHquinase_II PF01220.19 KDO24199.1 - 0.13 11.9 0.0 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Dehydroquinase class II FtsJ PF01728.19 KDO24199.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase LVIVD PF08309.11 KDO24200.1 - 4.8e-16 57.8 0.0 0.0034 16.7 0.0 5.5 5 0 0 5 5 5 5 LVIVD repeat JAB PF01398.21 KDO24201.1 - 1.3e-16 60.6 0.0 2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KDO24201.1 - 1.5e-07 32.2 0.0 2.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain FHA PF00498.26 KDO24202.1 - 4.8e-13 49.3 0.0 1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO24202.1 - 2.7e-05 24.4 0.0 0.00014 22.1 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 PF16770.5 KDO24202.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Pyr_redox_dim PF02852.22 KDO24202.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPRY PF00622.28 KDO24203.1 - 2.7e-22 79.2 0.0 5.2e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Telomere_Sde2_2 PF13297.6 KDO24203.1 - 1.6e-18 66.1 0.1 3.3e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 KDO24203.1 - 3.9e-18 65.8 1.2 6.6e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain zf-CCCH PF00642.24 KDO24203.1 - 0.017 15.0 1.9 0.044 13.7 1.9 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO24203.1 - 0.5 10.2 3.0 1.9 8.4 3.0 2.0 1 0 0 1 1 1 0 CCCH-type zinc finger Frigida PF07899.11 KDO24204.1 - 0.0073 15.6 1.0 18 4.5 0.0 3.2 3 0 0 3 3 3 3 Frigida-like protein Rad52_Rad22 PF04098.15 KDO24206.1 - 2.3e-43 147.7 0.0 3.3e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PI3_PI4_kinase PF00454.27 KDO24207.1 - 2e-28 99.9 0.0 1.3e-25 90.7 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 KDO24207.1 - 2e-06 28.3 0.6 3.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 PH domain Choline_transpo PF04515.12 KDO24208.1 - 1.6e-27 96.6 4.4 1.6e-27 96.6 4.4 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter PRD1_DD PF11087.8 KDO24208.1 - 2.5 7.8 5.3 0.47 10.2 0.7 2.2 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery Choline_transpo PF04515.12 KDO24209.1 - 4.8e-13 49.0 2.8 7.6e-13 48.4 2.8 1.3 1 0 0 1 1 1 1 Plasma-membrane choline transporter Arm PF00514.23 KDO24211.1 - 3.4e-82 268.3 20.2 5.4e-13 48.5 0.0 9.4 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO24211.1 - 1.2e-25 89.6 0.1 7.6e-07 29.4 0.0 5.3 1 1 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.6 KDO24211.1 - 5.2e-25 87.5 9.3 1.7e-10 41.2 0.0 7.3 6 2 0 6 6 6 4 HEAT-like repeat HEAT PF02985.22 KDO24211.1 - 1.4e-20 71.6 4.7 3.8e-05 23.6 0.0 8.5 9 0 0 9 9 9 5 HEAT repeat Arm_3 PF16186.5 KDO24211.1 - 1.2e-16 60.0 0.0 8e-16 57.3 0.2 2.1 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 KDO24211.1 - 2.2e-15 56.9 1.1 4.7e-15 55.8 1.1 1.6 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.20 KDO24211.1 - 8.7e-05 21.3 0.0 0.65 8.5 0.0 3.3 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KDO24211.1 - 0.00018 21.6 0.0 0.038 14.1 0.0 3.8 4 0 0 4 4 4 1 V-ATPase subunit H Arm_2 PF04826.13 KDO24211.1 - 0.00023 20.7 0.0 0.33 10.4 0.1 2.8 1 1 2 3 3 3 2 Armadillo-like RICTOR_V PF14668.6 KDO24211.1 - 0.00044 20.4 0.6 7.5 6.9 0.1 4.3 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KDO24211.1 - 0.00094 19.6 1.8 0.99 10.3 0.1 5.1 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat IFRD PF05004.13 KDO24211.1 - 0.016 14.3 0.2 0.96 8.5 0.0 3.4 2 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 KDO24211.1 - 0.028 14.4 0.4 1.3 9.1 0.0 3.1 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain LIP1 PF15904.5 KDO24214.1 - 0.17 12.2 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Seipin PF06775.14 KDO24215.1 - 1.1e-35 123.5 1.1 1.8e-35 122.8 1.1 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) AMP-binding PF00501.28 KDO24216.1 - 1.6e-80 270.8 0.0 2.1e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KDO24216.1 - 3.1e-11 43.5 0.0 3.8e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.6 KDO24216.1 - 0.00084 19.6 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_4 PF13637.6 KDO24217.1 - 4.7e-08 33.4 0.0 8.8e-07 29.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO24217.1 - 9.6e-08 32.2 0.5 0.032 14.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO24217.1 - 7.2e-07 29.7 0.2 1.9e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO24217.1 - 0.00049 20.3 0.5 0.0017 18.7 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24217.1 - 0.0014 18.9 0.4 0.72 10.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat DUF751 PF05421.11 KDO24217.1 - 0.015 16.0 0.8 0.025 15.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF751) DUF4366 PF14283.6 KDO24217.1 - 0.047 13.7 1.4 0.083 12.9 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 KDO24217.1 - 0.057 13.3 0.3 0.078 12.9 0.3 1.2 1 0 0 1 1 1 0 Rifin DUF4611 PF15387.6 KDO24217.1 - 0.091 13.0 1.8 2.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Adeno_E3_CR2 PF02439.15 KDO24217.1 - 0.16 11.7 1.4 0.32 10.8 1.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ank_2 PF12796.7 KDO24218.1 - 5.9e-17 62.0 1.0 1.5e-12 47.9 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24218.1 - 1.2e-14 54.4 0.1 3.4e-07 30.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24218.1 - 3.4e-13 49.5 0.1 1.6e-06 28.3 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO24218.1 - 2.4e-12 46.7 0.1 0.00014 22.2 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KDO24218.1 - 8e-12 44.3 0.5 0.00014 22.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Dynactin PF12455.8 KDO24218.1 - 0.017 14.4 0.4 0.018 14.3 0.4 1.0 1 0 0 1 1 1 0 Dynein associated protein HALZ PF02183.18 KDO24219.1 - 5.9e-05 23.2 7.5 2.4 8.4 0.0 5.3 5 0 0 5 5 5 2 Homeobox associated leucine zipper TSC22 PF01166.18 KDO24219.1 - 0.0011 19.3 0.5 1.1 9.6 0.0 4.1 3 0 0 3 3 3 1 TSC-22/dip/bun family GIT_CC PF16559.5 KDO24219.1 - 0.008 16.0 0.3 0.1 12.5 0.1 3.1 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor MPS2 PF17060.5 KDO24219.1 - 0.0085 15.4 1.5 0.67 9.1 0.6 2.3 2 0 0 2 2 2 1 Monopolar spindle protein 2 ATG16 PF08614.11 KDO24219.1 - 0.021 15.1 45.1 1.3 9.2 1.0 4.4 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KDO24219.1 - 0.023 14.7 16.5 0.079 13.0 2.9 4.7 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KDO24219.1 - 0.055 13.0 25.7 0.077 12.6 7.6 4.0 2 1 1 3 3 3 0 Intermediate filament protein DUF4878 PF12870.7 KDO24219.1 - 0.059 13.7 0.4 1.6 9.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) YabA PF06156.13 KDO24219.1 - 0.071 13.8 10.8 9.4 6.9 0.2 5.0 2 1 2 5 5 5 0 Initiation control protein YabA ZapB PF06005.12 KDO24219.1 - 0.095 13.2 0.2 0.095 13.2 0.2 6.1 6 1 0 6 6 6 0 Cell division protein ZapB Gon7 PF08738.10 KDO24219.1 - 0.22 11.6 3.0 0.54 10.4 0.2 2.8 1 1 0 2 2 2 0 Gon7 family SHE3 PF17078.5 KDO24219.1 - 0.35 10.6 13.2 1 9.0 2.1 3.7 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DivIC PF04977.15 KDO24219.1 - 0.37 10.6 0.0 0.37 10.6 0.0 6.3 5 3 2 7 7 7 0 Septum formation initiator Spc7 PF08317.11 KDO24219.1 - 0.4 9.5 26.2 0.092 11.6 3.8 3.3 2 1 1 4 4 4 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KDO24219.1 - 0.41 10.4 16.1 1.5 8.6 6.3 3.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 Phage_fiber_2 PF03406.13 KDO24219.1 - 0.6 9.7 10.0 0.32 10.6 0.9 3.7 4 0 0 4 4 3 0 Phage tail fibre repeat bZIP_1 PF00170.21 KDO24219.1 - 0.74 9.9 3.4 6.6 6.9 0.1 4.0 4 0 0 4 4 4 0 bZIP transcription factor DUF5595 PF18077.1 KDO24219.1 - 1.4 9.1 4.1 59 3.8 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF5595) SlyX PF04102.12 KDO24219.1 - 3.6 8.3 32.7 1.9 9.1 2.8 7.2 4 1 5 9 9 9 0 SlyX BLOC1_2 PF10046.9 KDO24219.1 - 3.9 7.8 14.7 3.9 7.9 0.1 5.6 5 1 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KDO24219.1 - 6.2 7.2 25.8 0.27 11.7 8.7 3.1 2 1 1 4 4 3 0 Fez1 TPR_2 PF07719.17 KDO24220.1 - 7.6e-37 122.5 9.7 0.00015 21.6 0.0 10.2 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 KDO24220.1 - 2.6e-32 109.3 14.1 1.6e-05 24.5 0.0 8.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KDO24220.1 - 1.4e-30 102.9 6.2 0.001 19.1 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24220.1 - 1.2e-24 85.7 3.4 2.2e-06 27.2 0.0 8.2 5 1 3 8 8 8 5 TPR repeat TPR_12 PF13424.6 KDO24220.1 - 7.8e-19 67.7 11.1 0.00011 22.4 0.1 7.1 6 3 1 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24220.1 - 2.1e-18 66.7 0.5 0.00067 20.2 0.0 5.6 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO24220.1 - 6e-16 57.2 0.9 0.14 12.2 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO24220.1 - 1.9e-14 52.9 6.9 0.04 14.3 0.0 8.4 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO24220.1 - 8.8e-14 51.0 4.5 0.0099 16.6 0.0 8.5 6 3 3 10 10 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO24220.1 - 3.8e-13 49.5 12.3 0.0054 16.9 0.4 6.3 2 2 6 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KDO24220.1 - 6.4e-13 48.6 0.2 0.00046 20.3 0.0 5.3 1 1 4 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO24220.1 - 6.3e-11 42.6 0.7 0.23 12.0 0.1 6.4 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO24220.1 - 2.6e-08 34.0 9.3 16 6.4 0.0 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO24220.1 - 6.9e-07 28.9 9.7 3.6 7.6 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 KDO24220.1 - 7.2e-06 25.2 0.7 0.13 11.1 0.1 3.3 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KDO24220.1 - 4.3e-05 22.9 0.2 2.2 7.4 0.0 4.1 2 1 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO24220.1 - 0.0012 18.8 1.7 10 6.3 0.0 4.4 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KDO24220.1 - 0.0043 17.5 0.2 0.05 14.0 0.1 2.7 3 1 1 4 4 3 1 Bacterial transcriptional activator domain TPR_3 PF07720.12 KDO24220.1 - 0.0044 17.0 6.9 12 6.0 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat PknG_TPR PF16918.5 KDO24220.1 - 0.0082 14.9 0.1 2.9 6.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_MalT PF17874.1 KDO24220.1 - 0.0086 15.5 0.4 0.34 10.2 0.0 3.2 2 2 1 4 4 4 1 MalT-like TPR region SRP_TPR_like PF17004.5 KDO24220.1 - 0.013 15.5 1.8 1.5 8.8 0.0 3.2 2 2 0 2 2 2 0 Putative TPR-like repeat OMS28_porin PF03532.13 KDO24220.1 - 0.022 14.0 0.7 0.082 12.1 0.2 1.9 2 0 0 2 2 2 0 OMS28 porin Wzy_C_2 PF11846.8 KDO24220.1 - 0.089 12.7 0.1 4.5 7.1 0.0 3.3 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal PPR PF01535.20 KDO24220.1 - 0.31 11.4 2.6 48 4.5 0.1 4.5 5 0 0 5 5 4 0 PPR repeat F-box-like PF12937.7 KDO24221.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 F-box-like Motile_Sperm PF00635.26 KDO24222.1 - 6.7e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Erf4 PF10256.9 KDO24222.1 - 0.0018 18.4 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Rap1a PF18602.1 KDO24222.1 - 0.057 13.7 0.0 0.61 10.4 0.0 2.4 2 0 0 2 2 2 0 Rap1a immunity proteins cNMP_binding PF00027.29 KDO24223.1 - 5.9e-30 103.2 0.3 2.4e-12 46.7 0.0 5.1 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Imm52 PF15579.6 KDO24223.1 - 0.14 12.0 0.1 0.85 9.5 0.0 2.1 1 1 1 2 2 2 0 Immunity protein 52 AARP2CN PF08142.12 KDO24224.1 - 3.1e-29 100.9 0.1 3.3e-28 97.6 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KDO24224.1 - 1.9e-05 25.1 0.0 6.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO24224.1 - 3e-05 24.3 0.0 8.5e-05 22.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KDO24224.1 - 3.3e-05 23.5 0.0 0.012 15.2 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KDO24224.1 - 0.00017 21.4 0.5 0.0021 17.8 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KDO24224.1 - 0.00066 19.7 0.1 0.0029 17.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KDO24224.1 - 0.0009 19.8 0.1 0.0043 17.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KDO24224.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KDO24224.1 - 0.0033 17.6 0.0 0.0033 17.6 0.0 2.5 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KDO24224.1 - 0.0061 17.1 0.1 0.0061 17.1 0.1 2.6 2 1 1 3 3 1 1 AAA domain Viral_helicase1 PF01443.18 KDO24224.1 - 0.0075 16.0 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KDO24224.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KDO24224.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KDO24224.1 - 0.016 15.6 0.0 0.065 13.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KDO24224.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KDO24224.1 - 0.027 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 KDO24224.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KDO24224.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KDO24224.1 - 0.032 14.2 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KDO24224.1 - 0.042 13.8 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KDO24224.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KDO24224.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KDO24224.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KDO24224.1 - 0.09 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KDO24224.1 - 0.094 11.5 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 KDO24224.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase PAP2_C PF14360.6 KDO24225.1 - 1.1e-20 73.9 8.9 1.1e-20 73.9 8.9 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KDO24225.1 - 1.2e-06 28.3 9.6 2.2e-06 27.5 9.6 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KDO24225.1 - 3.1e-05 23.7 2.6 7.5e-05 22.5 2.6 1.6 1 0 0 1 1 1 1 PAP2 superfamily Zip PF02535.22 KDO24226.1 - 9.8e-23 80.9 13.6 1.1e-20 74.1 13.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter SpoIIIAC PF06686.11 KDO24226.1 - 1.4 9.1 7.6 0.27 11.4 2.4 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family FtsJ PF01728.19 KDO24228.1 - 5.6e-56 189.4 0.1 1.3e-55 188.3 0.1 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 KDO24228.1 - 9.2e-56 188.8 24.2 9.2e-56 188.8 24.2 3.7 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 KDO24228.1 - 2.8e-38 131.3 12.1 2.8e-38 131.3 12.1 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) RcsD_ABL PF16359.5 KDO24228.1 - 0.072 13.2 0.1 13 6.0 0.0 2.6 2 0 0 2 2 2 0 RcsD-ABL domain SPX PF03105.19 KDO24229.1 - 3.2e-18 66.8 24.9 1.2e-11 45.2 0.3 3.9 2 1 2 4 4 4 4 SPX domain Sporozoite_P67 PF05642.11 KDO24229.1 - 0.035 12.2 5.7 0.048 11.8 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 KDO24229.1 - 7.2 6.3 6.5 2.8 7.6 2.3 2.1 2 0 0 2 2 2 0 FAM176 family Motile_Sperm PF00635.26 KDO24230.1 - 8.3e-19 67.5 0.0 3e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF812 PF05667.11 KDO24230.1 - 0.0028 16.6 1.6 0.0034 16.4 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Rootletin PF15035.6 KDO24230.1 - 0.0092 16.0 1.9 0.015 15.4 1.9 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Ax_dynein_light PF10211.9 KDO24230.1 - 0.017 15.1 0.7 0.029 14.3 0.7 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain UvrD-helicase PF00580.21 KDO24230.1 - 0.063 12.8 0.9 0.09 12.3 0.9 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HALZ PF02183.18 KDO24230.1 - 1.1 9.6 4.9 4.5 7.6 2.0 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 KDO24230.1 - 1.4 8.7 4.3 2.1 8.2 2.7 2.0 1 1 1 2 2 2 0 Septum formation initiator Motile_Sperm PF00635.26 KDO24231.1 - 2e-17 63.0 0.0 6e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 KDO24231.1 - 0.0021 18.2 0.0 2.5 8.3 0.0 3.8 3 1 1 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KDO24232.1 - 6.8e-35 119.2 0.0 8.4e-17 61.0 0.0 2.2 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 KDO24232.1 - 2.1e-08 34.2 3.6 0.00018 21.6 0.1 2.5 2 1 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1741 PF08427.10 KDO24232.1 - 0.057 13.1 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) TMEM131_like PF12371.8 KDO24232.1 - 0.06 13.6 1.7 2.9 8.2 0.7 2.6 2 1 1 3 3 3 0 Transmembrane protein 131-like DUF5001 PF16392.5 KDO24232.1 - 0.12 12.3 0.0 6 6.9 0.0 2.4 2 0 0 2 2 2 0 Ig-like domain CDC48_2 PF02933.17 KDO24232.1 - 0.25 11.1 1.2 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 FKBP_C PF00254.28 KDO24233.1 - 2.3e-20 72.7 0.1 4.8e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KDO24233.1 - 6.3e-07 28.9 3.8 0.00028 20.6 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO24233.1 - 0.00021 21.2 8.1 0.11 12.7 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO24233.1 - 0.0018 18.5 0.2 2.1 8.7 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24233.1 - 0.015 14.9 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 KDO24233.1 - 0.016 15.4 1.2 6.3 7.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO24233.1 - 0.11 13.0 0.0 4.4 7.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO24233.1 - 0.18 12.7 0.0 74 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ_CXXCXGXG PF00684.19 KDO24233.1 - 0.22 11.9 2.5 0.43 11.0 2.5 1.5 1 0 0 1 1 1 0 DnaJ central domain Mito_carr PF00153.27 KDO24235.1 - 7.3e-67 221.4 0.2 3.6e-25 87.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Torus PF16131.5 KDO24236.1 - 3.4e-13 50.2 13.1 0.00012 22.7 0.6 3.8 1 1 2 3 3 3 3 Torus domain RRM_1 PF00076.22 KDO24236.1 - 5.7e-12 45.3 2.1 1.3e-11 44.2 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KDO24236.1 - 2e-11 43.5 28.0 5.3e-05 23.1 3.6 3.3 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KDO24236.1 - 1e-08 34.9 21.6 2.3e-05 24.2 4.1 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO24236.1 - 3e-08 33.3 20.6 0.0039 17.0 2.9 3.2 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KDO24236.1 - 3.5e-05 24.0 7.2 0.0071 16.5 3.1 2.7 2 0 0 2 2 2 2 Zinc-finger containing family RRM_5 PF13893.6 KDO24236.1 - 0.0016 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 KDO24236.1 - 0.075 13.5 13.7 1.5 9.4 1.5 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Lipase_3 PF01764.25 KDO24236.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) LRV_FeS PF05484.11 KDO24236.1 - 0.48 10.5 5.3 17 5.5 0.2 3.2 3 0 0 3 3 3 0 LRV protein FeS4 cluster DUF4789 PF16033.5 KDO24236.1 - 2.2 8.9 7.5 8 7.1 5.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4789) ABC_tran PF00005.27 KDO24237.1 - 1.4e-31 109.8 0.0 2.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO24237.1 - 3.4e-20 72.8 9.4 3.4e-20 72.8 9.4 1.6 2 0 0 2 2 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO24237.1 - 5.6e-08 32.5 0.4 1.7e-06 27.6 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 KDO24237.1 - 0.0012 18.6 1.1 0.0035 17.1 1.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO24237.1 - 0.0023 18.2 0.4 0.014 15.6 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO24237.1 - 0.004 17.6 0.2 0.0096 16.3 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KDO24237.1 - 0.008 15.9 0.1 0.019 14.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KDO24237.1 - 0.034 13.9 0.3 0.081 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KDO24237.1 - 0.048 13.2 2.4 0.32 10.5 1.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KDO24237.1 - 0.096 12.4 0.3 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KDO24237.1 - 0.1 12.6 0.1 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KDO24237.1 - 0.11 12.2 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SbcCD_C PF13558.6 KDO24237.1 - 0.18 12.1 0.3 2.7 8.3 0.3 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KDO24237.1 - 0.29 11.6 2.5 0.2 12.1 0.3 1.7 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 KDO24238.1 - 2e-49 168.2 0.0 2.6e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO24238.1 - 3.5e-47 161.0 0.0 5.1e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO24238.1 - 0.00058 18.8 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DAGAT PF03982.13 KDO24241.1 - 1.2e-16 60.5 0.0 1.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase NKAIN PF05640.14 KDO24241.1 - 0.18 11.0 3.5 0.64 9.2 2.0 2.1 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein DAGAT PF03982.13 KDO24242.1 - 4.6e-14 52.0 0.0 4.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Coiled PF05710.12 KDO24243.1 - 1.6 9.6 8.9 9.5 7.1 8.7 2.3 1 1 0 1 1 1 0 Coiled coil Chlorosome_CsmC PF11098.8 KDO24243.1 - 5 7.1 12.4 6.1 6.8 1.5 2.6 2 1 0 2 2 2 0 Chlorosome envelope protein C Phage_CI_repr PF07022.13 KDO24244.1 - 0.029 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain SMI1_KNR4 PF09346.10 KDO24244.1 - 0.04 14.3 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Methyltransf_5 PF01795.19 KDO24244.1 - 0.069 12.6 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family BRCT_2 PF16589.5 KDO24245.1 - 9.2e-13 48.4 0.2 1.9e-08 34.6 0.0 2.9 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO24245.1 - 3.1e-11 43.5 0.1 1.4e-06 28.6 0.0 2.8 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KDO24245.1 - 9e-07 28.7 0.0 5.5e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KDO24245.1 - 5e-06 26.5 0.0 0.00017 21.6 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KDO24245.1 - 0.0011 18.9 0.0 0.0081 16.1 0.0 2.5 2 1 0 2 2 2 1 twin BRCT domain TPR_2 PF07719.17 KDO24247.1 - 2e-05 24.3 0.1 0.13 12.5 0.0 2.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO24247.1 - 0.0015 18.3 0.0 0.92 9.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24247.1 - 0.0023 18.5 1.0 0.0037 17.9 1.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO24247.1 - 0.019 15.1 0.4 0.043 14.0 0.4 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24247.1 - 0.046 13.4 0.1 0.45 10.2 0.0 2.4 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 KDO24247.1 - 0.056 13.7 0.0 0.72 10.2 0.0 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KDO24248.1 - 2e-31 108.4 3.9 4.4e-13 49.6 0.0 6.3 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) TIR_2 PF13676.6 KDO24248.1 - 7e-29 100.8 0.0 7.5e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 TIR domain Ank_3 PF13606.6 KDO24248.1 - 6e-27 90.7 9.2 1e-05 25.5 0.1 9.7 9 1 1 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 KDO24248.1 - 1.8e-26 92.1 11.6 1.2e-07 32.1 0.1 8.4 5 2 3 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO24248.1 - 8.7e-25 86.0 11.2 1.8e-05 25.0 0.1 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KDO24248.1 - 2e-19 69.4 6.0 1.5e-08 34.7 0.1 7.0 3 1 3 7 7 7 3 Ankyrin repeats (many copies) TIR PF01582.20 KDO24248.1 - 1.9e-09 37.5 0.0 4.6e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 KDO24248.1 - 0.0036 17.6 0.0 1.7 8.9 0.1 3.3 3 1 0 3 3 3 1 MTH538 TIR-like domain (DUF1863) DUF1858 PF08984.11 KDO24248.1 - 0.12 12.6 0.3 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) PPR_2 PF13041.6 KDO24249.1 - 4.3e-12 46.0 0.0 0.6 10.4 0.0 6.2 5 1 1 6 6 6 4 PPR repeat family PPR_long PF17177.4 KDO24249.1 - 3.6e-08 33.0 9.1 0.0013 18.1 0.1 5.4 2 2 4 6 6 6 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KDO24249.1 - 1.6e-07 31.1 0.2 0.096 13.0 0.1 4.9 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 KDO24249.1 - 0.00014 21.9 0.1 18 5.5 0.0 5.2 4 1 1 5 5 5 2 Pentatricopeptide repeat domain HTH_46 PF15977.5 KDO24250.1 - 0.17 11.9 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding COPI_assoc PF08507.10 KDO24251.1 - 2e-05 24.6 7.3 2.8e-05 24.2 7.3 1.2 1 0 0 1 1 1 1 COPI associated protein DUF4064 PF13273.6 KDO24251.1 - 5.4 7.3 10.1 4e+02 1.3 10.5 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2892 PF11127.8 KDO24251.1 - 6.8 6.8 12.5 2.4 8.3 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) DUF4215 PF13948.6 KDO24253.1 - 1.2e-76 252.9 158.1 1.4e-08 35.0 1.9 15.1 9 3 5 14 14 14 13 Domain of unknown function (DUF4215) Tyrosinase PF00264.20 KDO24253.1 - 1.7e-25 90.6 0.1 3.2e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase CBM_1 PF00734.18 KDO24256.1 - 4.7e-26 90.4 27.7 1.8e-09 37.4 0.5 3.5 3 0 0 3 3 3 3 Fungal cellulose binding domain PT PF04886.12 KDO24256.1 - 1.1e-11 44.0 56.8 1.3e-05 24.6 21.9 4.6 4 1 0 4 4 4 3 PT repeat Cornifin PF02389.15 KDO24256.1 - 0.013 15.7 13.7 0.024 14.8 13.7 1.4 1 0 0 1 1 1 0 Cornifin (SPRR) family Dickkopf_N PF04706.12 KDO24256.1 - 2.3 8.8 7.9 0.98 10.0 0.1 3.1 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region PHD PF00628.29 KDO24257.1 - 1.1e-14 54.0 34.4 4.9e-10 39.2 9.3 2.8 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 KDO24257.1 - 0.0054 16.6 2.1 0.0054 16.6 2.1 3.8 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rap1_C PF11626.8 KDO24257.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Zf_RING PF16744.5 KDO24257.1 - 4.4 7.5 13.2 7.7 6.7 3.2 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger Kinesin PF00225.23 KDO24258.1 - 1.6e-95 319.9 0.0 3.1e-95 318.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO24258.1 - 4e-16 59.3 0.0 2.2e-15 56.9 0.0 2.3 3 0 0 3 3 3 1 Microtubule binding MAP65_ASE1 PF03999.12 KDO24258.1 - 2.4e-11 43.1 0.9 2.4e-11 43.1 0.9 4.1 3 1 0 4 4 4 1 Microtubule associated protein (MAP65/ASE1 family) RWD PF05773.22 KDO24258.1 - 0.042 14.1 0.9 0.23 11.7 0.0 2.7 2 0 0 2 2 2 0 RWD domain Methyltransf_14 PF08484.11 KDO24258.1 - 0.12 12.1 0.2 0.69 9.7 0.2 2.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain MetOD2 PF18548.1 KDO24258.1 - 0.4 10.8 7.4 7 6.8 1.2 3.1 2 0 0 2 2 2 0 Metanogen output domain 2 Kinesin PF00225.23 KDO24259.1 - 1.3e-97 326.7 2.1 1.6e-97 326.4 2.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO24259.1 - 4.7e-27 94.7 0.0 8.3e-25 87.5 0.1 2.6 2 1 0 2 2 2 1 Microtubule binding HTH_CodY PF08222.11 KDO24259.1 - 0.00096 18.7 0.1 0.0028 17.2 0.0 1.8 2 0 0 2 2 2 1 CodY helix-turn-helix domain TSC22 PF01166.18 KDO24259.1 - 0.029 14.7 0.1 7.2 7.0 0.0 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family FAM76 PF16046.5 KDO24259.1 - 0.045 13.1 0.6 0.078 12.3 0.6 1.3 1 0 0 1 1 1 0 FAM76 protein PhoH PF02562.16 KDO24259.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KDO24259.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KDO24259.1 - 0.27 11.3 1.9 28 4.7 0.5 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain PALP PF00291.25 KDO24262.1 - 1.5e-71 241.3 0.9 1.7e-71 241.1 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 KDO24263.1 - 2.7e-62 210.5 0.0 3.7e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24263.1 - 1.6e-40 139.0 0.0 2.5e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO24263.1 - 1.9e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO24263.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO24263.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO24263.1 - 0.016 14.0 0.0 0.046 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_L24e PF01246.20 KDO24266.1 - 1.2e-32 111.9 4.8 1.2e-32 111.9 4.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.9 KDO24266.1 - 1.4 9.2 5.9 2.5 8.5 0.9 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-U1 PF06220.12 KDO24267.1 - 1.5e-19 69.4 6.3 2.1e-19 69.0 6.3 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 KDO24267.1 - 0.041 13.8 1.5 0.057 13.3 1.5 1.2 1 0 0 1 1 1 0 CLIP1 zinc knuckle Syntaxin-6_N PF09177.11 KDO24268.1 - 0.006 17.1 0.5 0.006 17.1 0.5 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KDO24268.1 - 0.041 13.9 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 SNARE domain DUF948 PF06103.11 KDO24268.1 - 0.19 12.0 2.9 11 6.4 0.7 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AcylCoA_dehyd_C PF12186.8 KDO24268.1 - 0.39 10.9 3.0 12 6.1 0.0 3.2 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal TPR_MLP1_2 PF07926.12 KDO24268.1 - 7.1 6.7 8.2 5.5 7.1 2.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ank_2 PF12796.7 KDO24269.1 - 1.9e-21 76.4 4.5 4e-07 30.5 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO24269.1 - 8.8e-19 67.3 7.4 1.2e-06 28.6 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24269.1 - 1.5e-15 55.7 2.8 0.007 16.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KDO24269.1 - 1.3e-12 48.0 1.0 0.017 15.7 0.0 4.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO24269.1 - 1.5e-09 37.8 11.9 0.0014 19.0 0.2 6.0 6 0 0 6 6 6 3 Ankyrin repeat PRODH PF18327.1 KDO24269.1 - 0.052 13.8 4.2 1.7 8.9 0.3 2.9 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain ThiF PF00899.21 KDO24270.1 - 4.5e-47 160.4 0.0 6.4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KDO24270.1 - 0.0027 18.0 1.6 0.058 13.6 1.6 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KDO24270.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KDO24270.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KDO24270.1 - 0.049 12.9 0.5 0.075 12.3 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KDO24270.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC_tran_CTD PF16326.5 KDO24270.1 - 2.4 8.5 3.6 2.4 8.5 0.1 2.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain Thioredoxin PF00085.20 KDO24271.1 - 3.1e-129 422.2 0.1 2.4e-31 107.8 0.0 7.1 6 1 1 7 7 7 6 Thioredoxin Thioredoxin_2 PF13098.6 KDO24271.1 - 1.8e-30 105.6 1.3 3.3e-05 24.3 0.1 8.1 6 3 0 6 6 6 6 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO24271.1 - 1.8e-24 85.7 1.5 0.0053 16.9 0.0 6.5 6 0 0 6 6 6 6 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO24271.1 - 1.6e-21 76.4 6.3 0.09 13.1 0.0 10.8 6 5 5 11 11 11 5 Thioredoxin-like HyaE PF07449.11 KDO24271.1 - 8.6e-18 64.3 0.1 0.0037 17.2 0.0 5.9 6 0 0 6 6 6 4 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KDO24271.1 - 3.2e-16 59.9 0.1 0.0015 18.4 0.0 5.8 7 0 0 7 7 6 3 F plasmid transfer operon protein AhpC-TSA PF00578.21 KDO24271.1 - 1.7e-15 57.1 0.1 0.03 14.2 0.0 6.3 6 0 0 6 6 6 5 AhpC/TSA family OST3_OST6 PF04756.13 KDO24271.1 - 2.9e-15 56.4 0.0 0.0057 16.0 0.0 5.2 4 1 1 5 5 5 4 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KDO24271.1 - 9.2e-15 54.6 0.2 0.037 14.2 0.0 6.2 6 0 0 6 6 6 4 Glutaredoxin Thioredoxin_3 PF13192.6 KDO24271.1 - 8.4e-14 51.4 0.0 0.23 11.5 0.0 5.5 5 0 0 5 5 5 4 Thioredoxin domain Thioredoxin_9 PF14595.6 KDO24271.1 - 7.9e-09 35.4 0.0 0.16 11.7 0.0 5.3 5 0 0 5 5 5 2 Thioredoxin DUF836 PF05768.14 KDO24271.1 - 2.7e-08 34.1 0.0 4.8 7.7 0.0 5.7 6 0 0 6 6 6 3 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.6 KDO24271.1 - 6e-08 32.8 0.0 2 8.3 0.0 5.2 6 0 0 6 6 6 2 Thioredoxin-like domain DSBA PF01323.20 KDO24271.1 - 1.4e-05 25.0 0.7 0.23 11.2 0.0 5.4 5 2 1 6 6 6 1 DSBA-like thioredoxin domain DIM1 PF02966.16 KDO24271.1 - 0.0038 17.0 0.0 13 5.6 0.0 3.6 3 0 0 3 3 3 0 Mitosis protein DIM1 Thioredoxin_4 PF13462.6 KDO24271.1 - 0.021 15.0 1.8 33 4.6 0.0 5.3 6 1 1 7 7 6 0 Thioredoxin Calsequestrin PF01216.17 KDO24271.1 - 0.024 13.7 0.5 6.8 5.6 0.0 3.5 4 0 0 4 4 4 0 Calsequestrin zf_C2H2_ZHX PF18387.1 KDO24271.1 - 0.038 13.6 0.6 23 4.7 0.0 3.6 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain UCH_1 PF13423.6 KDO24271.1 - 0.071 12.7 0.3 16 5.0 0.0 3.8 4 1 0 5 5 4 0 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1_2 PF13586.6 KDO24271.1 - 0.15 12.4 0.0 1.1e+02 3.2 0.0 3.6 3 0 0 3 3 3 0 Transposase DDE domain Mu-like_Com PF10122.9 KDO24271.1 - 5.8 6.4 7.7 47 3.5 0.1 4.2 4 0 0 4 4 4 0 Mu-like prophage protein Com AMP-binding PF00501.28 KDO24272.1 - 1.3e-50 172.3 0.0 1.6e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO24272.1 - 0.0027 18.6 0.1 0.006 17.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Actino_peptide PF14408.6 KDO24272.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes Thioredoxin PF00085.20 KDO24273.1 - 1.3e-12 47.5 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KDO24273.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KDO24273.1 - 0.00029 20.3 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 KDO24273.1 - 0.00034 20.5 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 KDO24273.1 - 0.00085 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KDO24273.1 - 0.0013 19.2 0.1 0.0053 17.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KDO24273.1 - 0.067 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain ThiF PF00899.21 KDO24274.1 - 3.6e-47 160.8 0.0 5.1e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KDO24274.1 - 0.0026 18.0 1.6 0.054 13.7 1.6 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KDO24274.1 - 0.026 15.0 0.0 0.079 13.4 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KDO24274.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KDO24274.1 - 0.048 12.9 0.5 0.072 12.3 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KDO24274.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC_tran_CTD PF16326.5 KDO24274.1 - 0.3 11.4 1.8 0.44 10.8 0.1 2.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain COPI_assoc PF08507.10 KDO24275.1 - 2.5e-13 50.2 5.8 3.2e-13 49.9 5.8 1.1 1 0 0 1 1 1 1 COPI associated protein SAP130_C PF16014.5 KDO24275.1 - 0.043 12.9 3.9 0.066 12.3 3.9 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Thioredoxin PF00085.20 KDO24276.1 - 2.2e-28 98.2 0.0 3.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO24276.1 - 5e-05 23.7 0.1 0.00036 21.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KDO24276.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KDO24276.1 - 0.0023 17.8 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KDO24276.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 KDO24276.1 - 0.03 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KDO24276.1 - 0.032 14.5 0.0 0.83 10.0 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like DIM1 PF02966.16 KDO24276.1 - 0.039 13.7 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_9 PF14595.6 KDO24276.1 - 0.041 13.6 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 KDO24276.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.6 KDO24276.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain S-methyl_trans PF02574.16 KDO24277.1 - 3.1e-51 174.7 0.0 3.6e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase IQ PF00612.27 KDO24278.1 - 9.2e-19 65.4 80.5 0.0012 18.5 0.3 13.1 14 0 0 14 14 14 10 IQ calmodulin-binding motif TPR_1 PF00515.28 KDO24278.1 - 0.053 13.4 4.5 24 4.9 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO24278.1 - 0.1 12.5 11.3 1.4 8.9 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Nucleolin_bd PF16725.5 KDO24278.1 - 0.12 12.0 0.9 1.9 8.2 0.0 3.0 2 0 0 2 2 2 0 Nucleolin binding domain TPR_2 PF07719.17 KDO24278.1 - 4.1 7.8 10.4 18 5.7 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M22 PF00814.25 KDO24279.1 - 4.1e-87 292.3 0.0 5.1e-87 292.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family TIP41 PF04176.13 KDO24280.1 - 6e-42 143.1 0.1 6.9e-41 139.6 0.1 2.3 2 1 0 2 2 2 1 TIP41-like family DAGAT PF03982.13 KDO24281.1 - 8.3e-39 133.3 0.0 1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 KDO24282.1 - 1.9e-37 128.8 0.0 2.3e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KDO24282.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase DAGAT PF03982.13 KDO24283.1 - 8.3e-34 116.8 0.0 1.9e-33 115.7 0.0 1.4 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Cep57_CLD_2 PF14197.6 KDO24284.1 - 0.00022 21.3 9.5 0.00022 21.3 9.5 6.2 6 2 1 7 7 7 1 Centrosome localisation domain of PPC89 Cnn_1N PF07989.11 KDO24284.1 - 0.013 15.6 0.3 0.013 15.6 0.3 5.7 5 2 1 6 6 6 0 Centrosomin N-terminal motif 1 HisKA_3 PF07730.13 KDO24284.1 - 0.079 13.5 0.9 0.079 13.5 0.9 4.8 4 2 0 5 5 5 0 Histidine kinase Tox-URI2 PF15653.6 KDO24284.1 - 0.2 12.0 1.3 2 8.7 0.0 2.8 3 0 0 3 3 3 0 URI fold toxin 2 DivIVA PF05103.13 KDO24284.1 - 0.2 11.8 0.1 0.2 11.8 0.1 5.0 4 1 1 5 5 5 0 DivIVA protein HIP1_clath_bdg PF16515.5 KDO24284.1 - 0.28 11.8 38.1 0.057 14.0 6.3 4.4 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Surfac_D-trimer PF09006.11 KDO24284.1 - 0.93 9.4 4.9 25 4.9 0.6 3.9 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation FapA PF03961.13 KDO24284.1 - 1 7.9 13.9 1.3 7.6 2.2 2.8 1 1 2 3 3 3 0 Flagellar Assembly Protein A Lebercilin PF15619.6 KDO24284.1 - 1.4 8.6 35.3 0.53 9.9 2.8 4.7 4 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 KDO24284.1 - 2.4 8.4 28.0 0.26 11.6 2.7 5.9 6 0 0 6 6 6 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 KDO24284.1 - 5.9 7.0 29.5 0.047 13.7 2.1 5.8 6 1 0 6 6 6 0 TATA element modulatory factor 1 DNA binding MRP-S28 PF10213.9 KDO24284.1 - 9.1 6.7 8.3 5 7.6 0.1 3.3 3 1 0 3 3 3 0 Mitochondrial ribosomal subunit protein PhyH PF05721.13 KDO24285.1 - 2.1e-09 37.9 0.0 4.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PagP PF07017.11 KDO24285.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Homeobox_KN PF05920.11 KDO24286.1 - 1.3e-31 108.2 7.7 2.9e-16 59.1 0.1 3.0 3 0 0 3 3 3 2 Homeobox KN domain Homeodomain PF00046.29 KDO24286.1 - 9e-13 47.9 0.2 5.4e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Homeodomain Homez PF11569.8 KDO24286.1 - 0.017 14.6 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez PseudoU_synth_2 PF00849.22 KDO24287.1 - 2.7e-27 95.8 0.0 4.3e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KDO24287.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 S4 domain DUF1126 PF06565.12 KDO24288.1 - 1.3e-64 214.6 0.0 1.3e-24 86.0 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 KDO24288.1 - 0.021 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair E1-E2_ATPase PF00122.20 KDO24289.1 - 1.1e-12 47.9 11.3 7.4e-09 35.4 1.2 3.1 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 KDO24289.1 - 1.1e-08 34.6 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KDO24289.1 - 1.3e-06 28.4 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO24289.1 - 0.00073 19.9 0.1 0.0037 17.6 0.0 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase UCH PF00443.29 KDO24290.1 - 1.3e-50 172.3 0.0 1.8e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase E1-E2_ATPase PF00122.20 KDO24290.1 - 5e-49 166.3 1.0 1.2e-48 165.1 1.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KDO24290.1 - 4.4e-34 118.6 0.1 1.1e-33 117.3 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KDO24290.1 - 8.5e-32 109.4 18.6 3.4e-13 49.8 0.9 5.0 6 0 0 6 6 6 3 Heavy-metal-associated domain UCH_1 PF13423.6 KDO24290.1 - 4.6e-14 52.7 0.3 1.8e-12 47.5 0.3 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-GRF PF06839.12 KDO24290.1 - 2e-11 43.8 2.9 4.6e-11 42.6 2.9 1.7 1 0 0 1 1 1 1 GRF zinc finger HAD PF12710.7 KDO24290.1 - 0.073 13.5 0.1 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C4_Topoisom PF01396.19 KDO24290.1 - 0.53 10.1 6.5 0.046 13.5 1.1 2.0 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger E1-E2_ATPase PF00122.20 KDO24291.1 - 2.3e-47 160.9 0.8 4e-47 160.1 0.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KDO24291.1 - 1.1e-37 130.4 3.6 1.1e-37 130.4 3.6 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KDO24291.1 - 9.9e-10 38.7 0.2 6.2e-09 36.2 0.0 2.4 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KDO24291.1 - 1.7e-05 24.7 1.0 0.00014 21.7 0.8 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO24291.1 - 0.01 16.2 0.3 0.13 12.6 0.1 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KDO24291.1 - 0.18 11.9 0.3 21 5.3 0.0 3.3 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Consortin_C PF15281.6 KDO24291.1 - 0.2 11.7 0.4 0.51 10.3 0.4 1.6 1 0 0 1 1 1 0 Consortin C-terminus WD40 PF00400.32 KDO24292.1 - 3e-27 94.3 11.7 6.6e-06 26.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO24292.1 - 1.6e-16 60.4 2.2 7.6e-06 26.1 0.2 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO24292.1 - 1.8e-06 28.0 0.1 0.0015 18.4 0.1 2.8 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KDO24292.1 - 0.0049 14.9 0.0 0.039 12.0 0.0 2.0 2 0 0 2 2 2 1 IKI3 family Ge1_WD40 PF16529.5 KDO24292.1 - 0.057 12.4 0.6 4 6.3 0.0 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 KDO24293.1 - 6.4e-49 166.1 0.1 9.4e-49 165.5 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO24293.1 - 3.4e-27 95.0 0.0 1.6e-26 92.8 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO24293.1 - 4.1e-05 23.6 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KDO24293.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KDO24293.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain API5 PF05918.11 KDO24293.1 - 2.2 7.0 9.8 3.3 6.4 9.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SET PF00856.28 KDO24294.1 - 2.8e-06 27.8 0.0 0.00057 20.3 0.0 2.1 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 KDO24295.1 - 6.5e-13 47.9 8.7 0.0012 18.6 0.1 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO24295.1 - 1.2e-11 43.8 12.0 0.0039 17.2 0.5 5.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO24295.1 - 7.4e-11 41.4 7.3 0.0002 21.3 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO24295.1 - 7.5e-10 39.2 12.2 2.2e-05 24.8 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO24295.1 - 4e-09 36.6 5.7 0.0024 18.1 0.1 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO24295.1 - 7.1e-09 35.4 4.4 0.052 13.9 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO24295.1 - 5.8e-08 32.2 5.5 0.048 13.7 0.0 5.8 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO24295.1 - 2.1e-07 31.2 9.3 0.13 13.1 0.3 5.3 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24295.1 - 2.7e-06 27.9 0.6 0.0067 17.0 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO24295.1 - 3.8e-06 27.0 1.7 0.00031 20.9 0.1 3.0 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KDO24295.1 - 6.1e-05 22.6 0.5 5.2 6.8 0.0 5.1 4 1 1 5 5 5 1 TPR repeat TPR_6 PF13174.6 KDO24295.1 - 0.00019 21.9 2.1 0.23 12.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO24295.1 - 0.0012 19.0 0.2 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KDO24295.1 - 0.0016 17.8 3.5 0.87 8.7 0.1 3.0 3 1 1 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 KDO24295.1 - 0.01 14.9 0.5 1 8.3 0.1 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.20 KDO24295.1 - 0.011 15.6 0.1 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS SNAP PF14938.6 KDO24295.1 - 0.024 14.1 2.3 2 7.8 0.0 2.9 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.9 KDO24295.1 - 0.035 13.6 2.2 13 5.4 0.1 4.0 4 0 0 4 4 4 0 SHNi-TPR Sel1 PF08238.12 KDO24295.1 - 2.1 9.1 6.3 1.2 10.0 0.5 3.3 3 1 1 4 4 3 0 Sel1 repeat DUF1736 PF08409.11 KDO24296.1 - 1.9e-12 47.0 1.2 4.2e-12 45.9 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KDO24296.1 - 0.058 13.5 0.8 0.058 13.5 0.8 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO24296.1 - 0.21 11.4 7.1 0.17 11.8 1.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24296.1 - 0.55 10.0 5.9 10 5.9 0.6 3.1 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.6 KDO24296.1 - 5.2 7.4 6.1 6.5 7.1 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GlcNAc PF11397.8 KDO24298.1 - 6.8e-69 233.0 0.1 1.8e-55 188.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 KDO24298.1 - 8.4e-17 61.9 0.0 1.9e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KDO24298.1 - 2.9e-10 40.7 0.0 6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase_Tyr PF07714.17 KDO24299.1 - 5.4e-49 166.8 0.0 6.8e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO24299.1 - 9.2e-49 166.2 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO24299.1 - 0.00013 20.9 0.3 0.00019 20.3 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO24299.1 - 0.0092 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO24299.1 - 0.025 14.5 0.3 0.11 12.4 0.1 2.0 1 1 2 3 3 3 0 Phosphotransferase enzyme family PHBC_N PF12551.8 KDO24299.1 - 0.055 13.3 0.2 0.17 11.6 0.2 1.9 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Kinase-like PF14531.6 KDO24299.1 - 0.06 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO24299.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KDO24299.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DENN PF02141.21 KDO24301.1 - 1.4e-34 119.7 1.6 3.2e-34 118.5 1.6 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KDO24301.1 - 6e-07 30.1 2.7 7.8e-06 26.5 2.6 2.5 1 1 0 1 1 1 1 uDENN domain SBF2 PF12335.8 KDO24301.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.5 1 1 0 1 1 1 1 Myotubularin protein C2 PF00168.30 KDO24301.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 C2 domain Rieske PF00355.26 KDO24302.1 - 5.5e-06 26.2 0.3 9.9e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KDO24302.1 - 0.00039 20.3 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain CAF1C_H4-bd PF12265.8 KDO24304.1 - 8.1e-31 106.1 1.1 9.9e-30 102.6 0.4 3.0 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KDO24304.1 - 3.7e-30 103.5 19.4 1.2e-07 32.3 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KDO24304.1 - 4.3e-07 30.0 0.8 0.00051 20.0 0.1 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KDO24304.1 - 9.1e-05 22.7 0.7 0.18 12.1 0.0 3.9 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pax7 PF12360.8 KDO24304.1 - 0.14 12.4 1.0 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Paired box protein 7 SMC_Nse1 PF07574.13 KDO24305.1 - 1.2e-19 70.9 0.0 1.2e-15 57.9 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KDO24305.1 - 2.2e-06 27.8 7.8 2.2e-06 27.8 7.8 1.6 2 0 0 2 2 2 1 RING-like domain zf-HC5HC2H_2 PF13832.6 KDO24305.1 - 0.0021 18.2 1.2 0.0039 17.3 1.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO24305.1 - 0.019 15.2 6.8 0.066 13.5 6.9 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KDO24305.1 - 0.022 15.1 6.7 0.022 15.1 6.7 1.8 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 KDO24305.1 - 1.7 8.9 6.6 0.79 9.9 3.8 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 KDO24305.1 - 1.9 8.5 11.0 0.19 11.6 6.5 1.7 2 0 0 2 2 2 0 PHD-finger zf-RING_11 PF17123.5 KDO24305.1 - 7.8 6.3 9.0 1 9.1 3.9 2.2 2 1 1 3 3 3 0 RING-like zinc finger AAA_2 PF07724.14 KDO24306.1 - 8.7e-32 110.6 0.9 1e-24 87.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KDO24306.1 - 7.7e-13 49.0 4.3 4.6e-05 23.9 0.2 3.8 3 2 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KDO24306.1 - 4.7e-07 29.9 0.1 5.8e-05 23.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KDO24306.1 - 3e-05 24.0 0.0 0.00013 22.0 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 KDO24306.1 - 3.6e-05 23.0 0.1 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_28 PF13521.6 KDO24306.1 - 4.3e-05 23.8 0.0 0.00011 22.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KDO24306.1 - 5.1e-05 22.8 0.2 0.0036 16.7 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KDO24306.1 - 0.00015 22.0 1.6 0.0057 16.9 0.9 3.1 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KDO24306.1 - 0.00016 21.5 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KDO24306.1 - 0.0002 21.8 2.5 0.00096 19.6 1.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KDO24306.1 - 0.0003 20.1 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin G-alpha PF00503.20 KDO24306.1 - 0.00097 18.4 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.6 KDO24306.1 - 0.001 19.6 0.0 0.003 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KDO24306.1 - 0.0017 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain T2SSE PF00437.20 KDO24306.1 - 0.0022 17.1 0.1 0.0056 15.8 0.1 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein CPT PF07931.12 KDO24306.1 - 0.0023 17.8 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 KDO24306.1 - 0.0036 17.1 0.1 0.87 9.3 0.0 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KDO24306.1 - 0.0038 17.4 0.7 0.013 15.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KDO24306.1 - 0.0051 16.8 0.3 1.7 8.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 KDO24306.1 - 0.0091 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 KDO24306.1 - 0.0099 15.6 0.9 1.5 8.5 0.0 2.7 2 1 0 2 2 2 1 Cytidylate kinase GCD14_N PF14801.6 KDO24306.1 - 0.016 15.0 1.1 4.2 7.3 0.8 3.0 2 1 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term DEAD PF00270.29 KDO24306.1 - 0.018 14.8 0.7 0.29 10.9 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase zf-CW PF07496.15 KDO24307.1 - 1.2e-26 92.4 15.5 5.4e-16 58.4 7.6 2.4 2 0 0 2 2 2 2 CW-type Zinc Finger PHD PF00628.29 KDO24307.1 - 0.036 13.9 6.1 0.39 10.6 0.2 3.5 4 0 0 4 4 4 0 PHD-finger FAM220 PF15487.6 KDO24307.1 - 0.33 10.6 4.1 0.54 9.8 4.1 1.4 1 0 0 1 1 1 0 FAM220 family ABC2_membrane PF01061.24 KDO24308.1 - 2.6e-69 232.8 47.3 1.3e-34 119.4 17.8 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO24308.1 - 2.2e-40 138.4 0.0 4.3e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO24308.1 - 5.9e-09 36.1 1.6 0.0066 16.3 0.2 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO24308.1 - 2.9e-07 31.0 0.0 0.01 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO24308.1 - 8.8e-07 29.0 0.0 0.00075 19.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO24308.1 - 1e-06 28.4 3.0 0.0038 16.9 0.4 3.2 2 1 1 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO24308.1 - 1.4e-05 25.4 0.1 0.088 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KDO24308.1 - 5.2e-05 23.8 0.0 0.3 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KDO24308.1 - 6.8e-05 23.3 0.6 0.017 15.5 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KDO24308.1 - 0.00024 21.1 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_25 PF13481.6 KDO24308.1 - 0.00027 20.6 0.9 0.3 10.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KDO24308.1 - 0.00039 21.0 0.2 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO24308.1 - 0.0012 18.6 0.9 0.15 11.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KDO24308.1 - 0.0016 18.1 0.5 1.7 8.2 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO24308.1 - 0.0016 18.4 1.2 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 KDO24308.1 - 0.003 17.8 0.7 3.7 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KDO24308.1 - 0.0033 17.6 0.1 2 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KDO24308.1 - 0.0078 16.1 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KDO24308.1 - 0.0097 15.9 0.1 0.42 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC2_membrane_3 PF12698.7 KDO24308.1 - 0.011 14.9 47.4 0.064 12.4 21.7 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein MMR_HSR1 PF01926.23 KDO24308.1 - 0.012 15.7 0.1 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 KDO24308.1 - 0.017 14.6 0.0 5.2 6.4 0.0 3.4 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 KDO24308.1 - 0.028 14.8 1.1 7.1 7.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_11 PF13086.6 KDO24308.1 - 0.031 14.1 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO24308.1 - 0.037 14.4 2.5 0.08 13.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO24308.1 - 0.045 13.0 0.1 8.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KDO24308.1 - 0.046 13.4 0.5 7.6 6.2 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KDO24308.1 - 0.06 13.4 0.2 12 6.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 KDO24308.1 - 0.096 13.1 0.3 5.3 7.5 0.3 2.7 3 0 0 3 3 2 0 AAA domain Pkinase PF00069.25 KDO24309.1 - 2.1e-48 165.0 0.0 1.1e-26 93.8 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24309.1 - 7.6e-42 143.4 0.0 3.9e-23 82.1 0.0 4.2 4 1 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.6 KDO24309.1 - 0.0074 15.6 0.0 0.38 10.0 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO24309.1 - 0.021 14.7 5.0 0.5 10.3 0.0 3.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.7 KDO24309.1 - 2.4 8.1 4.9 1.3 9.0 1.3 2.2 2 0 0 2 2 2 0 F-box-like Ank_5 PF13857.6 KDO24310.1 - 2.7e-11 43.5 1.7 3.9e-10 39.8 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24310.1 - 1.8e-09 37.0 1.2 3.1e-06 27.1 0.1 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KDO24310.1 - 2.3e-09 37.6 0.3 1.1e-08 35.5 0.3 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24310.1 - 2.6e-08 34.3 0.7 1.4e-07 32.0 0.3 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO24310.1 - 3.8e-07 30.3 4.8 3.1e-05 24.2 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat ADSL_C PF10397.9 KDO24310.1 - 0.44 11.1 2.3 0.66 10.6 0.1 2.5 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Spc7 PF08317.11 KDO24310.1 - 1 8.2 3.7 1.7 7.4 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 KDO24311.1 - 0.24 11.8 14.7 0.16 12.4 2.5 3.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KDO24311.1 - 1.7 8.7 14.2 1.3 9.1 0.6 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 KDO24312.1 - 6.9e-35 121.4 0.3 1e-34 120.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KDO24312.1 - 0.0019 18.6 0.3 0.0058 17.0 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO24312.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KDO24312.1 - 0.33 10.6 1.0 3.7 7.3 0.2 2.6 1 1 1 2 2 2 0 EF hand SHIPPO-rpt PF07004.12 KDO24313.1 - 1.1e-12 48.2 39.7 0.24 12.4 0.2 10.5 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat ECR1_N PF14382.6 KDO24313.1 - 0.21 11.4 14.4 12 5.8 0.0 6.8 8 0 0 8 8 8 0 Exosome complex exonuclease RRP4 N-terminal region PP2C PF00481.21 KDO24314.1 - 1.8e-42 145.7 0.2 2.3e-42 145.4 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO24314.1 - 1.6e-06 28.1 1.6 0.00012 22.1 0.1 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KDO24314.1 - 6e-06 26.0 1.6 2.1e-05 24.3 1.5 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3459 PF11941.8 KDO24314.1 - 0.034 14.4 0.2 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) GGACT PF06094.12 KDO24315.1 - 4.5e-19 69.2 0.0 6.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KDO24315.1 - 0.00026 21.3 0.0 0.00071 19.9 0.0 1.7 2 0 0 2 2 2 1 AIG2-like family 2OG-FeII_Oxy_3 PF13640.6 KDO24316.1 - 6e-17 62.3 0.0 1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KDO24316.1 - 2e-08 34.8 0.0 3.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA-synt_1b PF00579.25 KDO24317.1 - 2.8e-58 197.6 0.0 3.7e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2009 PF09418.10 KDO24318.1 - 1.7e-193 643.8 0.0 2.8e-193 643.1 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KDO24318.1 - 0.00017 21.6 12.3 0.00023 21.2 10.9 1.9 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 KDO24318.1 - 0.0054 16.9 7.7 0.012 15.9 7.7 1.4 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 KDO24318.1 - 0.65 10.3 6.4 2.2 8.6 5.9 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ank_3 PF13606.6 KDO24319.1 - 0.0014 18.9 0.1 0.0051 17.2 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KDO24319.1 - 0.0096 16.2 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24319.1 - 0.018 15.6 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KDO24319.1 - 0.026 15.0 0.0 0.063 13.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 KDO24320.1 - 5.3e-26 91.0 21.4 1.3e-11 44.9 1.5 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KDO24320.1 - 1.5e-15 56.9 9.1 0.0013 19.1 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KDO24320.1 - 1.1e-12 48.2 7.1 5.7e-05 23.6 1.1 4.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24320.1 - 8.2e-10 38.8 9.8 0.00024 21.4 0.5 4.3 2 1 2 5 5 5 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 KDO24320.1 - 5.1e-09 36.5 0.0 8.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 KDO24320.1 - 5.8e-08 32.4 7.2 0.44 11.3 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat SAM_2 PF07647.17 KDO24320.1 - 1.1e-06 28.6 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Brix PF04427.18 KDO24321.1 - 1.7e-38 132.7 0.0 2.3e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 KDO24322.1 - 3.6e-52 177.3 0.0 4.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24322.1 - 8e-28 97.4 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO24322.1 - 1.2e-05 24.7 0.4 2e-05 24.1 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO24322.1 - 9.7e-05 21.5 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO24322.1 - 0.00079 19.4 0.2 0.0047 16.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO24322.1 - 0.0016 17.8 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KDO24322.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KDO24322.1 - 0.042 13.4 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Viral_alk_exo PF01771.17 KDO24324.1 - 0.0045 15.9 8.1 0.0039 16.1 6.8 1.5 1 1 0 1 1 1 1 Viral alkaline exonuclease Pkinase PF00069.25 KDO24325.1 - 9.3e-51 172.7 0.0 1.3e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24325.1 - 1.3e-44 152.5 0.0 1.9e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO24325.1 - 1.1e-06 27.8 0.1 2.7e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KDO24325.1 - 0.008 16.1 0.3 0.008 16.1 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO24325.1 - 0.042 13.2 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CCDC53 PF10152.9 KDO24325.1 - 0.081 13.3 0.1 0.31 11.4 0.2 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PMP1_2 PF08114.11 KDO24325.1 - 0.21 11.3 0.3 0.48 10.2 0.3 1.5 1 0 0 1 1 1 0 ATPase proteolipid family DUF3123 PF11321.8 KDO24325.1 - 3.1 8.5 6.4 37 5.0 7.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) NAD_synthase PF02540.17 KDO24326.1 - 2.1e-26 92.6 0.3 1.7e-25 89.6 0.3 2.0 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 KDO24326.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CS PF04969.16 KDO24328.1 - 0.11 13.5 0.0 0.18 12.9 0.0 1.3 1 0 0 1 1 1 0 CS domain Apt1 PF10351.9 KDO24329.1 - 4.8e-38 131.2 0.0 2.2e-19 69.7 0.0 2.5 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KDO24329.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Guanylate_cyc PF00211.20 KDO24330.1 - 2.7e-09 36.9 0.0 6.3e-09 35.7 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain zf-SNAP50_C PF12251.8 KDO24330.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal TMCCDC2 PF15844.5 KDO24331.1 - 1.2 9.0 6.5 0.17 11.8 0.5 2.3 3 0 0 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 Guanylate_cyc PF00211.20 KDO24332.1 - 1.1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kelch_3 PF13415.6 KDO24333.1 - 3.8e-14 52.5 0.5 2.2e-06 27.8 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO24333.1 - 2.3e-12 46.6 0.0 0.00047 20.1 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KDO24333.1 - 2.1e-11 43.7 1.7 9.7e-05 22.3 0.1 3.1 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO24333.1 - 3.4e-06 27.1 0.2 0.013 15.8 0.0 3.2 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KDO24333.1 - 1.6e-05 24.3 0.1 0.006 16.1 0.0 3.4 3 1 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 KDO24333.1 - 0.0049 16.8 1.3 0.85 9.7 0.1 3.1 3 1 0 3 3 3 1 Kelch motif Pox_A_type_inc PF04508.12 KDO24335.1 - 0.16 11.8 0.3 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Phage_holin_7_1 PF16081.5 KDO24336.1 - 8 6.7 8.9 5.4 7.2 3.5 2.9 2 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MMR_HSR1 PF01926.23 KDO24338.1 - 3.4e-05 23.9 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RHD3 PF05879.12 KDO24338.1 - 5.6e-05 21.5 1.0 0.00063 18.0 0.0 2.5 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KDO24338.1 - 6.8e-05 22.3 0.3 0.00069 19.0 0.0 2.3 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KDO24338.1 - 0.00011 22.3 0.5 0.00044 20.3 0.3 2.0 1 1 1 2 2 2 1 Dynamin family T4_tail_cap PF11091.8 KDO24338.1 - 0.0056 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Tail-tube assembly protein MgtE_N PF03448.17 KDO24338.1 - 0.042 14.5 0.2 0.14 12.8 0.2 1.9 1 0 0 1 1 1 0 MgtE intracellular N domain Pox_A_type_inc PF04508.12 KDO24338.1 - 0.096 12.6 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Pkinase PF00069.25 KDO24339.1 - 1.2e-41 142.9 0.0 1.8e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24339.1 - 7e-41 140.2 0.0 1.1e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO24339.1 - 1.3e-08 34.8 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 KDO24339.1 - 0.017 15.1 0.1 0.05 13.5 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Vmethyltransf PF01660.17 KDO24339.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral methyltransferase Pkinase PF00069.25 KDO24340.1 - 1.2e-37 129.7 0.0 1.8e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24340.1 - 6.3e-37 127.3 0.0 8.6e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO24340.1 - 2.1e-07 30.9 0.0 4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ABC1 PF03109.16 KDO24340.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Myb_DNA-binding PF00249.31 KDO24341.1 - 7e-41 138.2 11.6 3.4e-14 52.8 0.4 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO24341.1 - 8.4e-30 102.8 6.8 8.1e-16 58.0 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO24341.1 - 6.2e-06 26.0 0.7 3.3e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 KDO24341.1 - 0.0014 18.7 3.3 1.3 9.2 1.1 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 KDO24341.1 - 0.013 15.6 0.0 2.1 8.4 0.0 3.0 2 1 1 3 3 3 0 SLIDE MADF_DNA_bdg PF10545.9 KDO24341.1 - 0.091 13.1 8.5 5.4 7.4 0.6 3.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KDO24341.1 - 0.11 12.8 10.0 2.7 8.4 1.2 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 KDO24342.1 - 2.8e-16 59.9 0.9 1.6e-07 31.8 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24342.1 - 3.1e-14 53.1 1.6 2.2e-08 34.5 0.6 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24342.1 - 8.9e-14 51.4 4.2 1.2e-05 25.5 0.6 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO24342.1 - 9.2e-12 44.9 7.5 0.0036 17.7 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KDO24342.1 - 1.5e-10 40.3 4.6 0.076 13.6 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat PIN_3 PF13470.6 KDO24342.1 - 2.2 9.1 5.5 1 10.2 1.4 2.6 3 0 0 3 3 3 0 PIN domain PSP1 PF04468.12 KDO24343.1 - 2.5e-26 91.8 3.6 4.3e-26 91.0 3.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PB1 PF00564.24 KDO24344.1 - 5.6e-07 29.4 0.0 7.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Ank_2 PF12796.7 KDO24345.1 - 1.7e-13 51.0 0.1 3.4e-05 24.4 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24345.1 - 1.3e-11 44.8 3.9 4.9e-06 27.0 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24345.1 - 4.8e-06 26.5 0.3 3.8 8.4 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KDO24345.1 - 1.5e-05 25.2 0.2 0.0053 17.0 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Suv3_C_1 PF18147.1 KDO24345.1 - 0.075 12.9 0.1 0.82 9.6 0.0 2.6 2 0 0 2 2 2 0 Suv3 C-terminal domain 1 eIF3_subunit PF08597.10 KDO24345.1 - 0.091 12.7 8.7 0.13 12.2 8.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SYCE1 PF15233.6 KDO24345.1 - 0.32 11.1 6.3 0.55 10.3 6.3 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF4407 PF14362.6 KDO24345.1 - 0.99 8.7 9.8 1.7 7.9 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dus PF01207.17 KDO24346.1 - 1.2e-70 238.1 0.5 1.4e-70 237.8 0.5 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KDO24346.1 - 0.00031 20.3 0.1 0.0006 19.3 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KDO24346.1 - 0.00074 19.0 5.1 0.011 15.1 4.3 2.2 2 1 0 2 2 2 1 Nitronate monooxygenase G3P_antiterm PF04309.12 KDO24346.1 - 0.015 14.7 1.7 0.023 14.1 0.1 2.1 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 KDO24346.1 - 0.021 14.1 1.3 0.021 14.1 1.3 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KDO24346.1 - 0.032 13.3 1.6 0.05 12.6 1.6 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain SOR_SNZ PF01680.17 KDO24346.1 - 0.085 12.6 1.1 0.21 11.4 0.7 1.8 2 0 0 2 2 2 0 SOR/SNZ family DHO_dh PF01180.21 KDO24346.1 - 0.22 10.7 0.7 0.42 9.8 0.7 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase FYVE PF01363.21 KDO24347.1 - 3.6e-17 62.3 11.6 3.6e-17 62.3 11.6 2.7 3 0 0 3 3 3 2 FYVE zinc finger Jiv90 PF14901.6 KDO24347.1 - 0.029 14.5 1.2 0.029 14.5 1.2 2.0 1 1 1 2 2 2 0 Cleavage inducing molecular chaperone Prok-RING_2 PF14445.6 KDO24347.1 - 0.031 14.4 1.7 0.031 14.4 1.7 3.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 2 FYVE_2 PF02318.16 KDO24347.1 - 0.11 12.8 16.6 0.1 12.9 3.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger C1_2 PF03107.16 KDO24347.1 - 2.4 8.5 20.8 0.36 11.2 4.6 3.3 2 1 0 2 2 2 0 C1 domain Mannosyl_trans2 PF04188.13 KDO24348.1 - 1.6e-54 185.9 31.5 6.2e-52 177.4 31.5 2.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) COMM_domain PF07258.14 KDO24349.1 - 1.5e-11 44.2 0.0 2.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 COMM domain SBF PF01758.16 KDO24349.1 - 0.031 14.0 0.1 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 Sodium Bile acid symporter family Got1 PF04178.12 KDO24350.1 - 5.2e-25 88.1 13.2 7e-25 87.7 13.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1624 PF07786.12 KDO24350.1 - 0.00053 19.6 0.1 0.00053 19.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) DUF2207 PF09972.9 KDO24350.1 - 0.98 8.1 9.2 6.4 5.4 9.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PRA1 PF03208.19 KDO24350.1 - 1.5 8.5 7.4 2.1 8.0 7.4 1.3 1 0 0 1 1 1 0 PRA1 family protein Phage_holin_3_6 PF07332.11 KDO24350.1 - 2.7 8.1 9.7 0.71 9.9 1.3 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_L27A PF00828.19 KDO24351.1 - 1.1e-23 84.3 0.2 1.6e-23 83.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4988 PF16378.5 KDO24351.1 - 0.18 11.5 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Ank_4 PF13637.6 KDO24353.1 - 8.2e-10 39.0 0.1 0.00052 20.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24353.1 - 8.7e-10 39.1 0.0 2.8e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO24353.1 - 7.7e-09 35.7 0.1 1.5e-06 28.4 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO24353.1 - 4.6e-07 30.0 0.0 0.076 13.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO24353.1 - 7.9e-05 22.8 0.1 0.63 10.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat WW PF00397.26 KDO24353.1 - 0.0011 18.9 1.6 0.0027 17.8 1.6 1.6 1 0 0 1 1 1 1 WW domain PIN_6 PF17146.4 KDO24353.1 - 0.1 13.1 2.6 16 6.1 0.1 3.2 3 1 0 3 3 3 0 PIN domain of ribonuclease IQ PF00612.27 KDO24353.1 - 0.24 11.3 3.8 0.21 11.5 1.1 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif Selenoprotein_S PF06936.11 KDO24353.1 - 4.8 6.9 7.3 0.7 9.7 3.3 1.6 2 0 0 2 2 2 0 Selenoprotein S (SelS) WD40 PF00400.32 KDO24356.1 - 5.9e-06 26.9 4.3 28 5.8 0.0 6.1 6 0 0 6 6 6 0 WD domain, G-beta repeat TBCA PF02970.16 KDO24356.1 - 0.0093 16.3 2.9 0.013 15.9 1.9 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor A ZapB PF06005.12 KDO24356.1 - 0.017 15.6 3.1 0.017 15.6 3.1 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 KDO24356.1 - 0.27 11.6 6.0 0.24 11.8 1.4 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF3450 PF11932.8 KDO24356.1 - 0.29 10.4 3.6 0.57 9.4 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 KDO24356.1 - 0.31 11.7 1.0 0.65 10.7 1.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Mto2_bdg PF12808.7 KDO24356.1 - 0.33 11.3 6.1 2.6 8.4 0.5 2.4 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ATG16 PF08614.11 KDO24356.1 - 0.55 10.4 7.3 0.94 9.7 7.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 KDO24356.1 - 1.3 9.3 9.3 0.15 12.3 4.4 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 KDO24356.1 - 1.5 9.1 5.0 18 5.6 0.8 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II zf-C2HC_2 PF13913.6 KDO24357.1 - 4e-13 48.9 2.4 1.9e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type DUF2256 PF10013.9 KDO24357.1 - 0.059 13.5 1.6 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) PyrI_C PF02748.15 KDO24357.1 - 0.09 12.7 1.0 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 KDO24357.1 - 0.12 12.9 2.5 4 8.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 KDO24357.1 - 0.25 11.2 1.8 13 5.7 0.5 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 KDO24357.1 - 0.32 11.9 4.3 13 7.0 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.9 KDO24357.1 - 0.38 10.9 4.0 0.55 10.3 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger domain ELM2 PF01448.24 KDO24358.1 - 7.5e-06 26.6 0.0 1.9e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 ELM2 domain BAH PF01426.18 KDO24358.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 BAH domain Menin PF05053.13 KDO24360.1 - 0.7 8.2 4.0 1 7.7 4.0 1.1 1 0 0 1 1 1 0 Menin NUP50 PF08911.11 KDO24360.1 - 0.85 10.3 8.5 1.4e+02 3.3 6.9 3.4 2 1 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) HMG_box PF00505.19 KDO24361.1 - 5.1e-19 68.4 4.0 5.1e-19 68.4 4.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KDO24361.1 - 1.5e-12 47.9 2.9 1.5e-12 47.9 2.9 2.0 2 1 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 KDO24361.1 - 0.022 15.3 5.1 0.022 15.3 5.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KDO24361.1 - 0.24 11.9 5.6 0.29 11.7 5.0 1.5 1 1 0 1 1 1 0 YABBY protein GTP_EFTU_D3 PF03143.17 KDO24362.1 - 6e-43 145.7 0.0 1.2e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 KDO24362.1 - 5.1e-39 133.8 0.0 2.8e-37 128.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KDO24362.1 - 1.5e-14 54.1 1.9 2.1e-14 53.6 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO24362.1 - 7.5e-06 26.0 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 KDO24362.1 - 0.053 13.6 0.2 0.16 12.0 0.1 1.8 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 KDO24362.1 - 0.1 12.5 1.7 0.15 12.0 0.2 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 CAF1 PF04857.20 KDO24363.1 - 1.7e-84 283.7 0.4 2.1e-84 283.4 0.4 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KDO24363.1 - 2.5e-05 24.0 0.1 0.034 13.8 0.0 3.3 4 0 0 4 4 4 2 3'-5' exonuclease Evr1_Alr PF04777.13 KDO24364.1 - 4.8e-25 87.9 0.6 7.2e-25 87.4 0.1 1.5 2 0 0 2 2 2 1 Erv1 / Alr family RCC1 PF00415.18 KDO24365.1 - 7.2e-68 225.0 13.6 3.9e-12 46.6 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO24365.1 - 7.3e-36 121.2 43.8 1.4e-07 31.1 0.4 8.2 7 2 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat NUP50 PF08911.11 KDO24365.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) ChpXY PF10216.9 KDO24366.1 - 0.065 12.4 0.0 8.6 5.4 0.0 2.2 2 0 0 2 2 2 0 CO2 hydration protein (ChpXY) Ku PF02735.16 KDO24367.1 - 5.7e-41 140.5 0.0 9.9e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KDO24367.1 - 1.6e-17 63.7 0.0 3.2e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 KDO24367.1 - 1.2e-15 57.9 0.2 2.2e-15 57.0 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 KDO24367.1 - 1.7e-10 41.5 1.5 2.7e-07 31.2 0.4 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA PF00092.28 KDO24367.1 - 5.5e-05 23.5 0.3 0.00013 22.2 0.3 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KDO24367.1 - 0.022 15.5 0.4 0.06 14.0 0.4 1.8 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm RPAP2_Rtr1 PF04181.13 KDO24368.1 - 7.8e-16 58.2 0.7 1.7e-15 57.1 0.7 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family SAWADEE PF16719.5 KDO24368.1 - 0.06 13.3 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 SAWADEE domain WD40 PF00400.32 KDO24369.1 - 8.6e-11 42.2 10.1 3.3e-05 24.5 0.2 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF5018 PF16410.5 KDO24369.1 - 0.018 13.7 0.0 0.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5018) Cgr1 PF03879.14 KDO24370.1 - 2.6e-09 37.4 29.2 3.2e-09 37.1 29.2 1.1 1 0 0 1 1 1 1 Cgr1 family DUF3565 PF12088.8 KDO24370.1 - 0.054 13.4 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) Membralin PF09746.9 KDO24370.1 - 4.9 6.1 9.0 6 5.8 9.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Snapin_Pallidin PF14712.6 KDO24372.1 - 5.6e-09 36.3 0.0 7.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Snapin/Pallidin NPV_P10 PF05531.12 KDO24372.1 - 0.086 13.3 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Reprolysin_4 PF13583.6 KDO24373.1 - 1 8.9 8.2 0.83 9.3 5.6 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like NPV_P10 PF05531.12 KDO24373.1 - 7.7 7.1 32.1 0.45 11.0 1.4 6.8 3 1 3 6 6 6 0 Nucleopolyhedrovirus P10 protein Nucleoside_tran PF01733.18 KDO24374.1 - 1.9e-13 50.5 13.9 7.7e-11 41.9 13.9 2.3 1 1 0 1 1 1 1 Nucleoside transporter Hva1_TUDOR PF11160.8 KDO24376.1 - 0.12 12.5 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain DUF4200 PF13863.6 KDO24376.1 - 0.14 12.5 51.6 0.057 13.8 10.9 5.2 1 1 3 5 5 5 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 KDO24376.1 - 0.33 11.1 29.4 2.3 8.4 4.3 4.4 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family RGCC PF15151.6 KDO24376.1 - 0.52 10.5 9.4 0.079 13.2 0.6 3.1 2 1 2 4 4 4 0 Response gene to complement 32 protein family FlaC_arch PF05377.11 KDO24376.1 - 0.92 10.0 17.0 0.39 11.1 0.6 6.2 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.10 KDO24376.1 - 1.1 9.1 7.0 18 5.2 0.3 3.8 4 0 0 4 4 4 0 DASH complex subunit Duo1 DUF3037 PF11236.8 KDO24376.1 - 1.1 9.7 22.4 0.035 14.5 4.3 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3037) DUF3584 PF12128.8 KDO24376.1 - 1.3 6.5 53.3 0.033 11.7 14.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 KDO24376.1 - 2.4 8.5 48.5 0.091 13.2 15.4 3.4 1 1 2 3 3 3 0 Fez1 GAS PF13851.6 KDO24376.1 - 5.4 6.3 46.6 0.83 9.0 15.6 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KDO24376.1 - 5.4 7.2 58.8 0.89 9.7 18.1 4.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KDO24376.1 - 7.7 5.9 52.0 3.3 7.1 21.0 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 IF4E PF01652.18 KDO24377.1 - 8.7e-57 191.4 0.5 1.2e-56 190.9 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Lactamase_B_6 PF16661.5 KDO24379.1 - 2e-08 33.9 0.0 2.2e-06 27.2 0.0 2.6 2 1 1 3 3 3 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KDO24379.1 - 8.5e-08 32.5 0.0 5.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Proteasome PF00227.26 KDO24380.1 - 1.4e-45 155.2 1.7 1.6e-45 155.0 1.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase_Tyr PF07714.17 KDO24381.1 - 9.6e-68 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO24381.1 - 2.1e-56 191.2 0.0 2.7e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO24381.1 - 0.0056 15.7 0.0 0.015 14.2 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KDO24381.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO24381.1 - 0.11 12.4 0.1 0.79 9.6 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO24381.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_1 PF00583.25 KDO24382.1 - 1.9e-05 24.9 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO24382.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO24382.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-LSD1 PF06943.12 KDO24382.1 - 3.4 7.6 5.3 3.1 7.7 0.1 3.0 3 0 0 3 3 3 0 LSD1 zinc finger GN3L_Grn1 PF08701.11 KDO24383.1 - 1.2e-15 57.4 20.0 1.2e-15 57.4 20.0 3.6 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KDO24383.1 - 3.3e-14 52.9 0.2 8.9e-12 45.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO24383.1 - 5.5e-10 39.0 0.2 1.5e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO24383.1 - 6.8e-07 29.3 0.8 0.036 14.0 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase BUD22 PF09073.10 KDO24383.1 - 0.00047 19.6 10.0 0.00047 19.6 10.0 2.6 2 1 0 2 2 1 1 BUD22 AIG1 PF04548.16 KDO24383.1 - 0.0011 18.3 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 KDO24383.1 - 0.0039 16.6 0.3 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Sigma70_ner PF04546.13 KDO24383.1 - 0.0089 15.9 6.5 0.0089 15.9 6.5 2.9 3 1 0 3 3 2 1 Sigma-70, non-essential region AAA_16 PF13191.6 KDO24383.1 - 0.016 15.6 3.9 0.16 12.3 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 KDO24383.1 - 0.031 14.5 0.0 0.97 9.7 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KDO24383.1 - 0.033 13.8 1.5 0.11 12.0 0.4 2.3 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KDO24383.1 - 0.11 11.7 1.0 4.3 6.4 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit Dynamin_N PF00350.23 KDO24383.1 - 0.44 10.6 0.0 0.44 10.6 0.0 4.3 3 2 1 4 4 4 0 Dynamin family AAA_18 PF13238.6 KDO24383.1 - 0.48 11.0 0.0 0.48 11.0 0.0 3.5 3 1 1 4 4 3 0 AAA domain YL1 PF05764.13 KDO24383.1 - 1.7 8.7 46.7 0.054 13.6 18.4 2.6 3 0 0 3 3 3 0 YL1 nuclear protein NOA36 PF06524.12 KDO24383.1 - 3.5 6.9 26.4 0.045 13.1 18.7 1.7 2 0 0 2 2 2 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KDO24383.1 - 6 7.1 29.9 0.15 12.3 14.5 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 KDO24383.1 - 9.6 5.7 21.0 0.17 11.5 13.2 2.0 2 0 0 2 2 2 0 PPP4R2 Trm112p PF03966.16 KDO24384.1 - 2.3e-14 53.7 0.0 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.10 KDO24384.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain ADK_lid PF05191.14 KDO24384.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid RVT_3 PF13456.6 KDO24385.1 - 2.2e-23 82.4 0.1 2.5e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 KDO24385.1 - 1.7e-10 41.2 0.3 7.3e-10 39.2 0.3 1.8 1 1 0 1 1 1 1 RNase H FANCAA PF15146.6 KDO24385.1 - 0.031 13.4 0.3 0.033 13.3 0.3 1.0 1 0 0 1 1 1 0 Fanconi anemia-associated Pkinase PF00069.25 KDO24386.1 - 6.2e-79 265.1 0.0 7.7e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24386.1 - 2.8e-36 125.1 0.0 3.5e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO24386.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO24386.1 - 0.002 17.5 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KDO24386.1 - 0.017 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KDO24386.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KDO24386.1 - 0.12 11.2 0.0 0.35 9.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Ribonuclease_3 PF00636.26 KDO24387.1 - 6.4e-07 30.0 0.9 0.0046 17.6 0.1 3.2 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KDO24387.1 - 0.0038 17.4 0.2 2.5 8.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease-III-like Anoctamin PF04547.12 KDO24388.1 - 9.5e-79 265.3 10.2 1.2e-78 265.0 10.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ECF_trnsprt PF12822.7 KDO24388.1 - 0.0066 16.6 3.1 0.62 10.1 0.5 3.2 2 1 1 3 3 3 2 ECF transporter, substrate-specific component Synaphin PF05835.12 KDO24389.1 - 9.5 6.5 7.2 1 9.7 0.7 2.3 2 0 0 2 2 2 0 Synaphin protein Maf1 PF09174.10 KDO24390.1 - 1.5e-47 162.0 0.1 3.1e-47 161.0 0.1 1.5 1 1 0 1 1 1 1 Maf1 regulator GreA_GreB_N PF03449.15 KDO24390.1 - 0.038 14.2 1.8 0.073 13.2 1.8 1.4 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Acetyltransf_9 PF13527.7 KDO24391.1 - 9.8e-06 25.7 0.3 3.3e-05 24.0 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO24391.1 - 0.00023 21.1 0.0 0.00027 20.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO24391.1 - 0.00035 20.9 0.0 0.00051 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KDO24391.1 - 0.0055 16.9 0.5 0.0084 16.3 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO24391.1 - 0.0066 16.7 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1678 PF07913.11 KDO24391.1 - 0.058 13.2 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) DUF2156 PF09924.9 KDO24391.1 - 0.061 12.3 0.1 0.077 12.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) PanZ PF12568.8 KDO24391.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ BSP PF04450.12 KDO24392.1 - 0.031 14.1 0.1 1.9 8.2 0.1 2.4 1 1 1 2 2 2 0 Peptidase of plants and bacteria Pkinase PF00069.25 KDO24393.1 - 1.8e-48 165.2 0.0 3.9e-34 118.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24393.1 - 3.1e-29 102.0 0.0 2.2e-20 73.0 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KDO24393.1 - 0.00059 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 KDO24393.1 - 0.074 12.6 0.4 0.45 10.1 0.1 2.3 2 1 0 2 2 2 0 PQQ-like domain DEC-1_N PF04625.13 KDO24393.1 - 0.1 11.6 2.2 0.19 10.7 2.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Roughex PF06020.11 KDO24393.1 - 0.17 10.9 3.2 0.34 9.9 3.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein MatE PF01554.18 KDO24394.1 - 2.4e-26 92.3 31.4 6.9e-17 61.6 7.1 2.3 2 0 0 2 2 2 2 MatE DUF3938 PF13074.6 KDO24394.1 - 0.26 11.6 2.7 5.1 7.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Ins145_P3_rec PF08709.11 KDO24395.1 - 1e-10 41.2 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF4704 PF15787.5 KDO24396.1 - 7.2e-07 28.7 0.1 2e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 KDO24396.1 - 2.2e-05 24.6 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Dynein_light PF01221.18 KDO24397.1 - 2.1e-43 146.6 1.8 2.3e-43 146.4 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 adh_short PF00106.25 KDO24398.1 - 5.2e-46 156.6 0.5 7e-46 156.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO24398.1 - 4e-31 108.4 0.2 5e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO24398.1 - 7.7e-09 35.7 2.9 2.8e-08 33.9 2.9 1.8 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KDO24398.1 - 0.026 13.9 0.2 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiA PF01656.23 KDO24398.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Transketolase_N PF00456.21 KDO24399.1 - 1.2e-147 491.3 0.0 1.8e-147 490.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KDO24399.1 - 1.1e-36 126.2 0.0 1.9e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KDO24399.1 - 6.3e-08 32.5 0.1 2.2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KDO24399.1 - 0.002 17.4 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase CYYR1 PF10873.8 KDO24399.1 - 0.2 12.1 0.6 0.36 11.3 0.6 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Mito_carr PF00153.27 KDO24400.1 - 2.6e-63 210.0 0.1 1e-20 73.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Transketolase_N PF00456.21 KDO24401.1 - 3.5e-57 193.9 0.0 7.4e-57 192.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KDO24401.1 - 1.3e-07 31.5 0.1 2.3e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Lactamase_B_5 PF14597.6 KDO24401.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Terpene_synth PF01397.21 KDO24401.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain CGI-121 PF08617.10 KDO24402.1 - 2.1e-35 122.2 0.3 2.4e-35 122.1 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF1218 PF06749.12 KDO24404.1 - 0.011 16.2 1.2 1.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) NSP11 PF06471.12 KDO24404.1 - 0.042 12.3 0.3 0.054 12.0 0.3 1.1 1 0 0 1 1 1 0 NSP11 Robl_LC7 PF03259.17 KDO24404.1 - 0.06 13.1 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain PTEN_C2 PF10409.9 KDO24406.1 - 1.3e-16 60.5 0.0 2.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KDO24406.1 - 0.00037 20.3 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO24406.1 - 0.00069 19.7 0.3 0.01 15.8 0.1 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO24406.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO24406.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate PX PF00787.24 KDO24407.1 - 7.8e-10 38.7 0.1 1.4e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 PX domain Exo_endo_phos PF03372.23 KDO24407.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ICMT PF04140.14 KDO24407.1 - 0.18 12.2 0.1 0.49 10.8 0.0 1.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MPS2 PF17060.5 KDO24408.1 - 0.00084 18.7 0.2 0.00084 18.7 0.2 7.0 3 2 3 8 8 8 1 Monopolar spindle protein 2 THP2 PF09432.10 KDO24408.1 - 4.7 7.3 18.7 1.9 8.5 0.0 6.8 5 2 3 8 8 8 0 Tho complex subunit THP2 CBM_1 PF00734.18 KDO24409.1 - 2.3e-05 24.3 2.9 2.3e-05 24.3 2.9 2.4 2 1 0 2 2 2 1 Fungal cellulose binding domain RPAP3_C PF13877.6 KDO24410.1 - 4.5e-18 65.6 0.1 7.5e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KDO24410.1 - 5.4e-13 48.2 0.5 0.00055 19.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO24410.1 - 3.9e-08 32.8 1.6 0.015 15.4 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24410.1 - 0.00031 20.4 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 KDO24410.1 - 0.00057 20.1 0.6 0.031 14.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO24410.1 - 0.0047 17.0 3.1 0.7 10.0 0.3 3.6 2 1 2 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KDO24410.1 - 0.0056 16.8 0.2 6.3 7.3 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO24410.1 - 0.0062 16.5 0.2 0.069 13.2 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO24410.1 - 0.015 15.4 0.7 2.6 8.3 0.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24410.1 - 0.067 13.9 5.7 0.18 12.4 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO24410.1 - 0.22 11.8 11.2 0.99 9.7 4.9 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO24410.1 - 0.5 10.3 2.6 10 6.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CBM_1 PF00734.18 KDO24411.1 - 2.9e-13 49.5 30.2 4.3e-09 36.2 9.9 2.5 2 1 0 2 2 2 2 Fungal cellulose binding domain Dickkopf_N PF04706.12 KDO24411.1 - 0.034 14.6 6.2 0.1 13.1 0.8 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region CBM_1 PF00734.18 KDO24412.1 - 2.3e-24 85.0 28.2 9.6e-13 47.8 7.0 2.6 3 0 0 3 3 3 2 Fungal cellulose binding domain MS_channel PF00924.18 KDO24413.1 - 1.4e-23 83.5 1.2 2.6e-12 46.7 1.4 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel Foie-gras_1 PF11817.8 KDO24414.1 - 2.2e-23 83.2 1.9 3.5e-23 82.5 1.9 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 TRAPPC10 PF12584.8 KDO24414.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KDO24414.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking RabGAP-TBC PF00566.18 KDO24415.1 - 5.8e-23 81.7 0.0 1.3e-22 80.6 0.1 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 KDO24415.1 - 9.7e-12 45.3 0.0 4.7e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO24415.1 - 4.8e-06 27.0 0.4 0.024 15.0 0.1 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KDO24415.1 - 0.017 15.4 1.6 1.1 9.6 0.1 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Mito_carr PF00153.27 KDO24416.1 - 1.3e-63 211.0 4.9 4.7e-22 77.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.28 KDO24417.1 - 7.7e-41 140.8 0.1 9.6e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KDO24417.1 - 3.4e-12 46.6 5.9 6.6e-12 45.7 4.6 2.2 2 1 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Aha1_N PF09229.11 KDO24418.1 - 5.4e-23 81.7 0.0 6.5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF1849 PF08904.11 KDO24418.1 - 0.03 13.9 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Pkinase_Tyr PF07714.17 KDO24419.1 - 2.6e-51 174.4 0.0 3.7e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO24419.1 - 2.1e-47 161.7 0.0 3.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO24419.1 - 0.0046 16.3 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KDO24419.1 - 0.023 13.6 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO24419.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO24419.1 - 0.037 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KDO24420.1 - 3.8e-68 229.7 0.0 5.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24420.1 - 5.8e-31 107.7 0.0 9.2e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KDO24420.1 - 1.6e-12 47.4 0.0 5e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 KDO24420.1 - 1.1e-06 28.2 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KDO24420.1 - 0.00029 20.5 0.1 1.5 8.4 0.0 3.0 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 KDO24420.1 - 0.00071 20.2 0.3 0.0024 18.5 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KDO24420.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO24420.1 - 0.036 13.0 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain TGT PF01702.18 KDO24421.1 - 2.2e-104 349.4 0.0 5.7e-103 344.7 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Chitin_synth_1 PF01644.17 KDO24422.1 - 1.7e-38 132.2 0.4 9.4e-36 123.3 0.4 2.5 1 1 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KDO24422.1 - 6e-29 101.1 1.6 4.5e-20 71.8 0.0 3.3 3 0 0 3 3 3 3 Chitin synthase Glyco_trans_2_3 PF13632.6 KDO24422.1 - 3.9e-10 40.0 4.8 2.2e-09 37.5 4.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KDO24422.1 - 1.4e-06 28.4 0.0 2.3e-05 24.4 0.0 2.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 MIT PF04212.18 KDO24422.1 - 3.5e-06 27.0 1.2 8.2e-06 25.8 0.3 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Chitin_synth_1N PF08407.11 KDO24422.1 - 4.7e-06 26.5 0.1 1.9e-05 24.5 0.2 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Presenilin PF01080.17 KDO24425.1 - 2e-110 369.3 5.1 5.3e-110 367.9 5.1 1.6 1 1 0 1 1 1 1 Presenilin DUF2722 PF10846.8 KDO24425.1 - 0.02 13.9 3.9 0.028 13.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Afaf PF15339.6 KDO24425.1 - 0.28 10.9 4.8 0.13 11.9 0.3 2.3 2 1 0 2 2 2 0 Acrosome formation-associated factor TFIIA PF03153.13 KDO24425.1 - 0.43 10.5 8.6 0.7 9.8 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 KDO24425.1 - 0.87 10.0 4.4 0.74 10.2 1.2 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Androgen_recep PF02166.16 KDO24425.1 - 1.2 7.8 16.4 1.8 7.3 16.4 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 KDO24425.1 - 3.3 7.3 13.4 5 6.7 13.4 1.2 1 0 0 1 1 1 0 Spt20 family Aconitase PF00330.20 KDO24426.1 - 8.6e-145 483.3 0.0 1.1e-144 482.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KDO24426.1 - 1.7e-44 151.3 0.0 3.7e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1344 PF07076.11 KDO24426.1 - 0.042 13.7 0.0 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) DUF521 PF04412.13 KDO24426.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) TMEM107 PF14995.6 KDO24427.1 - 1.8e-19 70.4 1.2 2e-19 70.2 1.2 1.0 1 0 0 1 1 1 1 Transmembrane protein Ank_4 PF13637.6 KDO24431.1 - 5.6e-11 42.7 0.8 2.5e-06 27.9 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24431.1 - 5.1e-09 35.7 1.7 0.00056 20.2 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO24431.1 - 1.2e-08 35.4 0.2 1.6e-07 31.8 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO24431.1 - 4.1e-08 33.3 1.0 8.1e-05 22.8 0.3 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO24431.1 - 3.8e-06 27.1 2.5 0.00096 19.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Tricorn_PDZ PF14685.6 KDO24431.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ_6 PF17820.1 KDO24431.1 - 0.054 13.3 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 PDZ domain WW PF00397.26 KDO24432.1 - 3.8e-31 106.9 35.1 1.1e-08 34.9 3.4 4.4 4 0 0 4 4 4 4 WW domain Glyco_hyd_101C PF17451.2 KDO24432.1 - 0.0075 16.6 0.3 0.0075 16.6 0.3 4.8 5 1 0 5 5 5 2 Glycosyl hydrolase 101 beta sandwich domain YL1_C PF08265.11 KDO24432.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.9 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain RRM_1 PF00076.22 KDO24434.1 - 2.2e-33 113.9 0.0 5e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO24434.1 - 4.5e-09 36.3 0.0 0.00076 19.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif CDC45 PF02724.14 KDO24434.1 - 4.7 5.4 9.0 6.3 5.0 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KDO24434.1 - 5.2 6.7 6.5 13 5.4 6.5 1.8 1 0 0 1 1 1 0 FAM176 family Pyr_redox_2 PF07992.14 KDO24435.1 - 4.1e-70 236.3 6.0 6.8e-70 235.6 6.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO24435.1 - 2.8e-37 127.4 0.1 7e-37 126.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO24435.1 - 1.3e-20 73.7 9.1 4.5e-18 65.6 0.4 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO24435.1 - 5.2e-11 42.4 4.8 4.5e-08 32.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO24435.1 - 3.1e-10 40.0 0.7 3.1e-10 40.0 0.7 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO24435.1 - 4.8e-07 29.9 3.2 0.00056 20.1 0.7 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KDO24435.1 - 1.7e-06 27.4 15.2 7.2e-06 25.3 2.3 3.8 3 1 1 4 4 4 2 FAD binding domain GIDA PF01134.22 KDO24435.1 - 2e-06 27.1 5.9 2e-06 27.1 5.9 3.1 2 2 1 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KDO24435.1 - 1.7e-05 24.2 1.9 0.063 12.4 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KDO24435.1 - 3.9e-05 23.0 1.4 0.011 15.0 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KDO24435.1 - 5.4e-05 22.1 11.2 0.0054 15.5 0.8 3.9 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KDO24435.1 - 0.00012 21.4 1.2 0.0018 17.5 0.2 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KDO24435.1 - 0.00049 19.3 2.7 0.35 9.8 0.0 3.2 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KDO24435.1 - 0.0018 17.6 13.1 0.11 11.7 0.0 3.2 2 1 1 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 KDO24435.1 - 0.037 14.5 0.6 0.95 9.9 0.0 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding XdhC_C PF13478.6 KDO24435.1 - 0.097 13.2 0.0 19 5.8 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Epimerase PF01370.21 KDO24436.1 - 5.6e-11 42.4 0.0 1.2e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KDO24436.1 - 7e-10 38.5 0.0 2.8e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KDO24436.1 - 0.0089 15.2 1.2 0.015 14.5 0.2 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein CxC4 PF18717.1 KDO24436.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Ras PF00071.22 KDO24437.1 - 1.5e-35 122.2 0.0 1.9e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO24437.1 - 1e-11 45.1 0.0 1.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KDO24437.1 - 4.5e-05 23.5 0.0 6.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO24437.1 - 0.011 15.6 0.0 0.16 11.9 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KDO24437.1 - 0.023 15.1 0.0 0.033 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain YkuD_2 PF13645.6 KDO24437.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Ank_2 PF12796.7 KDO24438.1 - 9.1e-28 96.7 2.0 2.8e-13 50.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24438.1 - 6.1e-23 80.9 1.2 6.7e-06 26.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24438.1 - 1.6e-20 71.0 6.0 0.00034 20.8 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KDO24438.1 - 1.6e-17 63.1 1.7 1.7e-06 28.2 0.3 5.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO24438.1 - 6.5e-16 58.2 5.0 2.4e-06 27.7 0.3 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) HEAT PF02985.22 KDO24438.1 - 0.00079 19.5 16.0 4.4 7.8 0.1 8.0 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KDO24438.1 - 0.051 14.2 0.0 8.7 7.0 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KDO24438.1 - 0.082 13.1 0.2 6.9 6.9 0.0 3.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KDO24438.1 - 3.1 8.4 12.8 16 6.1 0.1 6.6 7 0 0 7 7 7 0 HEAT-like repeat tRNA-synt_1 PF00133.22 KDO24439.1 - 2.7e-38 131.6 0.0 2e-24 85.8 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KDO24439.1 - 1e-18 67.3 0.1 1.4e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KDO24439.1 - 3.3e-10 40.1 0.0 6.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KDO24439.1 - 3.7e-08 33.1 0.0 7.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Steroid_dh PF02544.16 KDO24440.1 - 5.3e-14 52.5 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase START PF01852.19 KDO24441.1 - 7.2e-24 84.4 0.0 9.1e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 START domain CusF_Ec PF11604.8 KDO24441.1 - 0.021 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Polyketide_cyc2 PF10604.9 KDO24441.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GSP_synth PF03738.14 KDO24442.1 - 2.4e-102 343.0 0.0 3.3e-102 342.5 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp GAF_2 PF13185.6 KDO24442.1 - 6.8e-05 23.2 0.1 0.00071 19.9 0.0 2.8 3 0 0 3 3 3 1 GAF domain Thioredoxin PF00085.20 KDO24442.1 - 0.0052 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin GAF PF01590.26 KDO24442.1 - 0.011 16.3 0.1 0.044 14.4 0.0 2.0 2 0 0 2 2 2 0 GAF domain Nop53 PF07767.11 KDO24443.1 - 0.12 11.8 5.4 0.15 11.4 5.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HemY_N PF07219.13 KDO24444.1 - 0.023 14.9 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus NnrU PF07298.11 KDO24444.1 - 0.057 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 NnrU protein Mito_carr PF00153.27 KDO24447.1 - 2e-49 165.5 6.9 2.7e-18 65.7 0.4 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein NAGLU PF05089.12 KDO24448.1 - 2.5e-129 431.0 4.9 3.3e-129 430.6 4.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KDO24448.1 - 6.2e-57 193.1 0.8 8.9e-57 192.6 0.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KDO24448.1 - 1.9e-11 43.5 0.0 8.9e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DsrC PF04358.13 KDO24448.1 - 0.19 12.2 0.1 0.63 10.6 0.0 1.9 2 0 0 2 2 2 0 DsrC like protein Thiolase_N PF00108.23 KDO24449.1 - 0.039 13.3 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1189 PF06691.11 KDO24449.1 - 0.85 9.1 2.4 1.2 8.7 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) PGK PF00162.19 KDO24450.1 - 1.7e-147 491.3 1.8 1.9e-147 491.1 1.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FtsJ PF01728.19 KDO24451.1 - 7.3e-50 169.5 0.0 8.7e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KDO24451.1 - 0.00083 19.2 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KDO24451.1 - 0.23 10.6 0.0 11 5.2 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family VIT1 PF01988.19 KDO24452.1 - 3.8e-10 40.0 1.6 4.9e-10 39.7 1.6 1.1 1 0 0 1 1 1 1 VIT family PRA1 PF03208.19 KDO24453.1 - 0.073 12.7 2.8 0.11 12.1 2.8 1.3 1 0 0 1 1 1 0 PRA1 family protein Ribosomal_S10 PF00338.22 KDO24456.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e Ras PF00071.22 KDO24458.1 - 5.1e-51 172.5 0.0 7.5e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO24458.1 - 2.5e-33 114.8 0.0 4.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO24458.1 - 4e-16 59.0 0.4 6.9e-16 58.2 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO24458.1 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO24458.1 - 6e-05 23.0 0.1 0.013 15.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KDO24458.1 - 0.00013 22.0 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO24458.1 - 0.00061 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO24458.1 - 0.0045 16.5 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO24458.1 - 0.011 14.9 0.1 0.084 12.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 KDO24458.1 - 0.025 15.1 0.0 0.08 13.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KDO24458.1 - 0.031 14.6 0.9 0.11 12.8 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KDO24458.1 - 0.074 13.1 0.3 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM PF00493.23 KDO24458.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 KDO24458.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KDO24458.1 - 0.16 11.7 0.1 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 KDO24458.1 - 0.18 10.6 1.4 0.21 10.4 0.1 1.7 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 KDO24458.1 - 0.2 11.1 0.1 0.67 9.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region LicD PF04991.13 KDO24459.1 - 0.048 13.8 4.3 0.061 13.5 4.3 1.1 1 0 0 1 1 1 0 LicD family Mo-nitro_C PF06967.11 KDO24460.1 - 0.0033 17.3 0.0 0.0075 16.2 0.0 1.6 2 0 0 2 2 2 1 Mo-dependent nitrogenase C-terminus Myosin_head PF00063.21 KDO24461.1 - 2.9e-199 663.7 0.0 4.5e-199 663.0 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 KDO24461.1 - 1.2e-10 41.4 0.1 3.2e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 PX domain IQ PF00612.27 KDO24461.1 - 4.2e-09 35.4 17.7 0.0029 17.2 0.1 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.6 KDO24461.1 - 0.03 14.6 0.2 0.28 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Collagen PF01391.18 KDO24461.1 - 0.11 12.3 3.1 0.23 11.3 3.1 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) AAA_16 PF13191.6 KDO24461.1 - 0.35 11.3 0.0 0.35 11.3 0.0 4.1 3 1 1 4 4 4 0 AAA ATPase domain Forkhead_N PF08430.12 KDO24461.1 - 0.47 11.1 3.6 1.1 9.9 3.6 1.5 1 0 0 1 1 1 0 Forkhead N-terminal region ABC_tran PF00005.27 KDO24461.1 - 0.54 10.8 2.3 2 8.9 0.0 3.0 4 0 0 4 4 4 0 ABC transporter Ras PF00071.22 KDO24463.1 - 1.3e-06 28.1 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO24463.1 - 7.7e-06 26.1 0.0 9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase HALZ PF02183.18 KDO24466.1 - 0.0032 17.6 0.4 0.0056 16.9 0.4 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Sigma70_ner PF04546.13 KDO24466.1 - 0.028 14.3 1.3 0.033 14.1 1.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3450 PF11932.8 KDO24466.1 - 0.081 12.2 4.9 0.11 11.8 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nefa_Nip30_N PF10187.9 KDO24466.1 - 0.084 13.2 1.6 0.13 12.6 1.6 1.2 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Motile_Sperm PF00635.26 KDO24467.1 - 9.9e-10 38.2 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KDO24467.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF3665 PF12427.8 KDO24467.1 - 0.35 10.6 1.7 0.8 9.4 1.7 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Glyco_hydro_18 PF00704.28 KDO24468.1 - 3.5e-39 135.4 0.1 4.1e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Solute_trans_a PF03619.16 KDO24470.1 - 1.1e-70 238.2 14.9 1.3e-70 237.9 14.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4231 PF14015.6 KDO24470.1 - 1 9.8 4.7 3.9 8.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DHHC PF01529.20 KDO24471.1 - 2e-28 99.2 9.4 2e-28 99.2 9.4 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase Phage_GPO PF05929.11 KDO24473.1 - 0.056 13.1 10.0 0.078 12.6 10.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Herpes_UL25 PF01499.16 KDO24473.1 - 0.19 10.2 7.8 0.26 9.7 7.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family AAA_23 PF13476.6 KDO24473.1 - 0.84 10.1 4.3 1.1 9.8 4.3 1.1 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 KDO24473.1 - 1.3 9.6 19.8 1.5 9.3 19.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KDO24473.1 - 3.2 8.0 13.2 6.5 7.0 13.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Complex1_LYR PF05347.15 KDO24474.1 - 0.013 15.5 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF2654 PF10849.8 KDO24474.1 - 0.091 13.0 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) ArfGap PF01412.18 KDO24477.1 - 9.1e-42 141.8 0.3 1.4e-41 141.2 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pericardin_rpt PF07054.11 KDO24477.1 - 0.002 18.2 16.8 0.002 18.2 16.8 8.2 3 1 4 8 8 8 2 Pericardin like repeat DUF747 PF05346.11 KDO24478.1 - 1.5e-88 297.4 18.2 2e-88 297.0 18.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3395 PF11875.8 KDO24479.1 - 1.4e-27 96.6 0.0 2.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KDO24479.1 - 5.1e-15 55.3 1.1 1e-14 54.4 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain FYVE PF01363.21 KDO24480.1 - 3.2e-14 52.8 15.1 6e-14 51.9 15.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF4723 PF15851.5 KDO24480.1 - 0.0048 17.0 2.6 0.055 13.6 2.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4723) FYVE_2 PF02318.16 KDO24480.1 - 0.062 13.5 11.6 0.2 11.8 11.6 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KDO24480.1 - 1.5 9.0 12.7 1.2 9.3 6.7 2.6 2 0 0 2 2 2 0 B-box zinc finger IBR PF01485.21 KDO24480.1 - 6.3 7.1 13.9 0.68 10.2 6.0 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain SHMT PF00464.19 KDO24481.1 - 8.8e-174 577.8 0.0 1e-173 577.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KDO24481.1 - 0.002 17.5 0.1 0.0035 16.7 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase PALP PF00291.25 KDO24482.1 - 6.9e-67 225.9 0.1 8.6e-67 225.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KDO24482.1 - 8.9e-12 45.3 0.3 2.6e-06 27.8 0.0 3.0 3 0 0 3 3 3 2 CBS domain DUF4916 PF16262.5 KDO24482.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DAGK_cat PF00781.24 KDO24482.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CLASP_N PF12348.8 KDO24484.1 - 4.3e-06 26.5 0.0 6.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal FYVE PF01363.21 KDO24487.1 - 4.3e-16 58.8 7.0 8.1e-16 57.9 7.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO24487.1 - 0.022 15.0 4.2 0.046 13.9 4.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 KDO24487.1 - 0.07 13.0 8.2 0.16 11.8 8.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KDO24487.1 - 0.11 12.5 6.2 0.26 11.3 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KDO24487.1 - 1.8 8.6 11.0 3.6 7.6 11.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Kinesin PF00225.23 KDO24488.1 - 1.5e-91 306.8 0.1 3.5e-91 305.6 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO24488.1 - 4.6e-46 156.5 0.0 1.4e-45 154.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding EzrA PF06160.12 KDO24488.1 - 0.00062 18.1 8.5 0.00062 18.1 8.5 2.9 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 KDO24488.1 - 0.061 12.2 29.9 0.15 10.9 13.7 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein ACBP PF00887.19 KDO24489.1 - 1.1e-26 92.8 0.1 2e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 KDO24489.1 - 8.6e-21 74.3 3.3 1.7e-13 50.9 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO24489.1 - 1e-17 63.9 4.6 6.3e-11 42.3 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO24489.1 - 1.5e-16 60.0 0.9 5.6e-06 26.6 0.5 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KDO24489.1 - 2.9e-14 53.2 0.6 1.1e-12 48.2 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24489.1 - 2.5e-11 42.7 0.5 0.00043 20.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Nucleoporin_FG2 PF15967.5 KDO24489.1 - 0.0076 14.8 0.8 0.013 14.1 0.8 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeated region Polysacc_deac_1 PF01522.21 KDO24491.1 - 3.9e-12 46.2 0.1 6.8e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase NMT1_2 PF13379.6 KDO24491.1 - 0.068 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Sec7 PF01369.20 KDO24492.1 - 4.8e-66 221.9 0.1 9.1e-66 221.0 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KDO24492.1 - 5.2e-41 140.2 3.3 5.2e-41 140.2 3.3 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KDO24492.1 - 2.6e-22 79.3 1.6 2.6e-22 79.3 1.6 2.4 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KDO24492.1 - 9.2e-16 57.5 10.2 4e-13 49.0 0.9 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 KDO24492.1 - 1.2e-05 23.7 0.0 0.00013 20.2 0.0 2.3 2 0 0 2 2 2 1 C-terminal region of Mon2 protein FAD_SOX PF18371.1 KDO24492.1 - 0.13 12.6 0.3 5.6 7.4 0.1 3.0 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Mg_trans_NIPA PF05653.14 KDO24493.1 - 1.3e-33 116.4 13.2 9.1e-22 77.5 1.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA YiaAB PF05360.14 KDO24493.1 - 2.3 8.5 7.9 1.5 9.1 0.2 3.2 3 0 0 3 3 3 0 yiaA/B two helix domain Pkinase PF00069.25 KDO24494.1 - 5.2e-66 222.7 0.0 7.4e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24494.1 - 1.8e-33 116.0 0.0 3.4e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO24494.1 - 3.3e-06 26.3 0.1 4.8e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO24494.1 - 0.00017 21.0 0.1 0.00064 19.1 0.1 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO24494.1 - 0.014 14.8 0.5 0.037 13.4 0.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO24494.1 - 0.033 14.1 0.9 0.21 11.5 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family PAN_4 PF14295.6 KDO24497.1 - 3.9e-07 29.9 11.5 0.00059 19.7 0.6 3.0 4 0 0 4 4 4 2 PAN domain PAN_3 PF08277.12 KDO24497.1 - 0.018 14.8 4.3 0.089 12.6 0.6 2.7 2 0 0 2 2 2 0 PAN-like domain Ank_2 PF12796.7 KDO24498.1 - 4.2e-26 91.4 4.3 3.4e-06 27.6 0.2 7.1 3 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24498.1 - 3.6e-19 68.9 18.3 1.2e-06 28.9 0.2 8.5 5 3 4 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24498.1 - 9.1e-16 57.7 20.6 0.047 14.0 0.1 11.2 6 3 7 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24498.1 - 7.4e-11 41.3 16.0 1.5 9.6 0.0 12.2 12 2 2 14 14 14 2 Ankyrin repeat Ank PF00023.30 KDO24498.1 - 0.0065 16.9 9.3 2 9.0 0.0 7.1 5 4 2 7 7 7 1 Ankyrin repeat DUF249 PF03158.13 KDO24498.1 - 0.18 11.5 0.0 41 3.8 0.0 3.1 3 0 0 3 3 3 0 Multigene family 530 protein PAN_1 PF00024.26 KDO24499.1 - 1.6e-05 24.7 0.6 2e-05 24.4 0.6 1.1 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KDO24499.1 - 0.00093 19.1 0.2 0.0014 18.5 0.2 1.3 1 0 0 1 1 1 1 PAN domain DUF4246 PF14033.6 KDO24500.1 - 6.7e-21 74.9 0.0 8.5e-18 64.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4246) Ank_2 PF12796.7 KDO24501.1 - 8.3e-28 96.8 7.9 2.5e-10 40.8 0.1 5.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24501.1 - 7e-22 77.5 1.2 0.0008 19.9 0.0 6.3 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24501.1 - 3e-19 68.8 2.0 2.7e-05 24.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24501.1 - 2.4e-17 61.2 7.5 0.0022 18.3 0.0 8.3 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 KDO24501.1 - 7.3e-13 48.3 0.2 0.02 15.3 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat DUF1488 PF07369.11 KDO24501.1 - 0.048 13.7 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) DEC-1_N PF04625.13 KDO24501.1 - 1.9 7.4 5.6 3.1 6.7 5.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.16 KDO24502.1 - 3e-22 79.0 21.7 8.6e-13 47.9 6.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KDO24502.1 - 0.00017 20.2 3.0 0.00017 20.2 3.0 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector BRO1 PF03097.18 KDO24503.1 - 4.7e-19 68.5 0.0 1.2e-18 67.1 0.0 1.6 1 1 0 1 1 1 1 BRO1-like domain zf-RING_7 PF02591.15 KDO24504.1 - 0.052 13.8 0.2 0.052 13.8 0.2 4.4 5 0 0 5 5 5 0 C4-type zinc ribbon domain WD40 PF00400.32 KDO24505.1 - 0.0004 21.1 12.8 1.2 10.2 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Tektin PF03148.14 KDO24505.1 - 0.0066 15.2 3.6 0.011 14.6 3.6 1.2 1 0 0 1 1 1 1 Tektin family Cortex-I_coil PF09304.10 KDO24505.1 - 0.047 13.9 2.5 0.087 13.1 2.5 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil ABC_tran_CTD PF16326.5 KDO24505.1 - 0.059 13.6 4.0 0.16 12.3 4.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain ATG16 PF08614.11 KDO24505.1 - 0.062 13.5 5.6 0.12 12.6 5.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GrpE PF01025.19 KDO24505.1 - 0.24 11.0 2.6 2.2 7.9 3.2 1.9 2 0 0 2 2 2 0 GrpE DUF4124 PF13511.6 KDO24505.1 - 0.61 10.5 3.4 0.68 10.3 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Glyco_hydro_72 PF03198.14 KDO24506.1 - 5.7e-26 91.5 1.5 3.4e-25 88.9 1.5 2.4 1 1 0 1 1 1 1 Glucanosyltransferase EGF_2 PF07974.13 KDO24506.1 - 1.5 9.2 15.1 5.2 7.5 15.1 2.0 1 0 0 1 1 1 0 EGF-like domain Cys_Knot_tox PF17486.2 KDO24506.1 - 2.7 8.3 12.5 1 9.6 9.0 2.0 2 0 0 2 2 2 0 Cystine knot toxins REJ PF02010.15 KDO24507.1 - 3.9e-47 161.1 10.1 9e-45 153.3 7.6 2.9 1 1 1 2 2 2 2 REJ domain GPS PF01825.21 KDO24507.1 - 5e-10 39.8 2.2 1.7e-09 38.1 2.2 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif zf-TRAF PF02176.18 KDO24507.1 - 0.00033 21.3 3.7 0.00033 21.3 3.7 4.1 3 1 1 4 4 4 2 TRAF-type zinc finger DUF4040 PF13244.6 KDO24507.1 - 0.01 15.9 0.4 0.074 13.2 0.4 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) EGF_2 PF07974.13 KDO24507.1 - 2.5 8.5 7.4 5.5 7.4 7.4 1.6 1 0 0 1 1 1 0 EGF-like domain CRCB PF02537.15 KDO24508.1 - 0.27 11.6 0.0 0.27 11.6 0.0 3.3 3 0 0 3 3 3 0 CrcB-like protein, Camphor Resistance (CrcB) ABC_membrane_2 PF06472.15 KDO24509.1 - 2.3e-80 269.9 3.3 3e-80 269.5 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KDO24509.1 - 8.7e-18 65.2 0.0 3.4e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KDO24509.1 - 0.00017 21.1 0.2 0.17 11.3 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO24509.1 - 0.00075 19.4 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO24509.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO24509.1 - 0.071 13.6 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO24509.1 - 0.091 12.5 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Phage_holin_2_3 PF16080.5 KDO24511.1 - 0.062 13.1 4.2 9.9 6.0 0.0 3.9 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Exo_endo_phos PF03372.23 KDO24512.1 - 6.8e-22 78.1 0.0 8.6e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KDO24514.1 - 1.5e-22 79.3 9.7 3.8e-05 24.0 0.1 5.5 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO24514.1 - 1.2e-15 57.0 17.1 4.2e-06 26.4 2.2 4.7 2 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KDO24514.1 - 1.7e-14 53.7 6.8 3.8e-12 46.0 2.0 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KDO24514.1 - 2.4e-08 33.4 18.6 0.55 10.4 0.2 8.4 9 1 1 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 KDO24514.1 - 0.00037 20.6 15.1 0.63 10.8 0.1 6.8 5 1 0 5 5 5 1 Leucine Rich Repeat CBS PF00571.28 KDO24515.1 - 4.9e-20 71.7 0.4 3e-10 40.4 0.5 2.2 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 KDO24515.1 - 0.033 14.3 0.2 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 PRC-barrel domain Amidase_2 PF01510.25 KDO24515.1 - 0.09 13.2 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase PLA2G12 PF06951.11 KDO24516.1 - 2e-17 63.7 13.8 3.7e-17 62.8 13.8 1.4 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Staphylcoagulse PF04022.12 KDO24516.1 - 0.092 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Staphylocoagulase repeat FAM110_N PF14161.6 KDO24516.1 - 0.11 12.7 0.3 0.62 10.3 0.1 2.1 2 0 0 2 2 2 0 Centrosome-associated N terminus TFIID_30kDa PF03540.13 KDO24517.1 - 1.8e-20 72.6 0.2 2.7e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TFIID-31kDa PF02291.15 KDO24517.1 - 0.0014 18.7 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO24517.1 - 0.016 15.2 0.0 0.1 12.6 0.0 2.3 1 1 1 2 2 2 0 Bromodomain associated TTL PF03133.15 KDO24518.1 - 2.3e-76 256.7 0.0 3.6e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO24518.1 - 1.6e-06 27.6 0.0 5.8e-05 22.5 0.0 2.7 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO24518.1 - 0.043 13.1 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-synt_E PF05680.12 KDO24518.1 - 1.7 9.1 4.4 5.6 7.4 4.3 2.0 2 0 0 2 2 2 0 ATP synthase E chain MFAP1 PF06991.11 KDO24518.1 - 2.9 7.7 9.3 5.7 6.7 9.3 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing RRM_1 PF00076.22 KDO24519.1 - 2.3e-17 62.6 0.0 4.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO24519.1 - 0.00063 19.3 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KDO24519.1 - 0.00099 19.1 3.8 0.0022 18.0 3.8 1.6 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 KDO24519.1 - 0.0081 16.6 0.3 0.014 15.8 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 KDO24519.1 - 0.021 14.8 1.9 0.042 13.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle PIH1_CS PF18201.1 KDO24520.1 - 8.7e-10 38.9 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 KDO24520.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Mito_carr PF00153.27 KDO24521.1 - 1.7e-61 204.1 4.6 1.2e-21 76.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ipi1_N PF12333.8 KDO24522.1 - 6e-12 46.1 3.0 3.1e-09 37.3 0.0 3.6 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 KDO24522.1 - 0.012 16.0 0.3 0.097 13.2 0.3 2.7 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 KDO24522.1 - 0.064 13.5 0.1 2.5 8.6 0.1 3.4 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.7 KDO24522.1 - 0.087 12.9 0.3 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Sec23_helical PF04815.15 KDO24522.1 - 0.24 11.2 2.2 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Sec23/Sec24 helical domain Mito_carr PF00153.27 KDO24523.1 - 1.6e-61 204.2 3.7 4.3e-22 77.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cas_GSU0054 PF09609.10 KDO24523.1 - 0.05 12.3 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Trypsin_2 PF13365.6 KDO24525.1 - 8.2e-32 111.2 2.1 1.5e-31 110.4 2.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO24525.1 - 3.4e-15 56.4 0.2 5.8e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KDO24525.1 - 1.5e-11 43.9 0.0 6.2e-11 42.0 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KDO24525.1 - 2.3e-11 43.9 0.0 7.7e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO24525.1 - 1.4e-06 28.6 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KDO24525.1 - 0.0061 15.3 3.4 0.037 12.7 0.5 2.1 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S32 PF05579.13 KDO24525.1 - 0.021 14.0 2.0 2.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.15 KDO24525.1 - 0.074 12.8 0.4 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 KDO24525.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.21 KDO24525.1 - 7.5 6.4 7.6 0.26 11.1 0.5 2.3 3 0 0 3 3 3 0 Peptidase S7, Flavivirus NS3 serine protease Ank_4 PF13637.6 KDO24528.1 - 8.1e-43 144.3 10.3 2.7e-13 50.1 0.1 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24528.1 - 1.9e-35 121.3 0.6 4.5e-19 68.8 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO24528.1 - 2.1e-30 103.8 9.8 1.2e-08 35.0 0.3 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KDO24528.1 - 3.8e-30 103.5 13.8 5.3e-08 33.0 0.0 5.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24528.1 - 7.5e-29 96.6 2.1 1.2e-06 28.4 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat VPS13 PF16908.5 KDO24529.1 - 1.2e-48 166.0 0.2 1.2e-48 166.0 0.2 3.1 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KDO24529.1 - 1e-24 86.9 0.1 3.1e-24 85.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KDO24529.1 - 2.4e-20 73.1 0.0 1.1e-18 67.6 0.0 3.0 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KDO24529.1 - 5.3e-14 52.2 6.6 7.6e-09 35.3 0.0 5.2 4 1 1 5 5 5 3 Repeating coiled region of VPS13 PDZ_6 PF17820.1 KDO24529.1 - 9.9e-07 28.5 0.0 2.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain VPS13_C PF16909.5 KDO24529.1 - 0.00041 20.2 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Tricorn_PDZ PF14685.6 KDO24529.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ PF00595.24 KDO24529.1 - 0.024 15.0 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Fzo_mitofusin PF04799.13 KDO24529.1 - 0.088 12.4 0.6 0.2 11.2 0.6 1.5 1 0 0 1 1 1 0 fzo-like conserved region PDZ_2 PF13180.6 KDO24529.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain EF-hand_7 PF13499.6 KDO24530.1 - 0.00022 21.6 1.1 0.0004 20.8 1.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO24530.1 - 0.00029 20.2 0.5 0.0085 15.6 0.0 2.7 2 1 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO24530.1 - 0.0021 17.8 3.6 0.014 15.3 1.8 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KDO24530.1 - 0.06 12.9 0.1 0.58 9.8 0.1 2.5 2 0 0 2 2 2 0 EF hand RPA_C PF08784.11 KDO24534.1 - 3.8e-14 53.2 1.5 4.1e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KDO24534.1 - 0.00034 20.5 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DIMCO_N PF16844.5 KDO24534.1 - 0.038 14.3 0.1 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal HTH_20 PF12840.7 KDO24534.1 - 0.056 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Anillin_N PF16018.5 KDO24534.1 - 0.15 12.7 0.1 0.25 12.0 0.1 1.3 1 0 0 1 1 1 0 Anillin N-terminus CC2D2AN-C2 PF15625.6 KDO24535.1 - 3.8e-17 62.6 0.0 8.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 KDO24535.1 - 0.0016 18.7 0.1 0.0067 16.7 0.0 2.0 2 0 0 2 2 2 1 C2 domain Actin PF00022.19 KDO24536.1 - 5.2e-147 489.7 0.0 1.7e-146 488.0 0.0 1.6 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 KDO24538.1 - 2.1e-43 148.6 0.0 1.1e-29 103.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24538.1 - 3e-23 82.4 0.0 4.2e-17 62.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO24538.1 - 9e-06 25.2 0.0 2.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KDO24538.1 - 0.075 12.6 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO24538.1 - 0.092 12.6 0.9 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family MAP70 PF07058.11 KDO24538.1 - 0.26 10.0 3.7 0.11 11.2 0.1 1.8 2 0 0 2 2 2 0 Microtubule-associated protein 70 Fez1 PF06818.15 KDO24538.1 - 0.36 11.3 4.4 0.18 12.2 1.8 1.7 2 0 0 2 2 2 0 Fez1 DivIC PF04977.15 KDO24538.1 - 0.54 10.1 3.8 1.3 8.8 3.8 1.6 1 0 0 1 1 1 0 Septum formation initiator PKcGMP_CC PF16808.5 KDO24538.1 - 1.8 8.5 8.8 1.8 8.5 2.1 2.5 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Macoilin PF09726.9 KDO24538.1 - 4.5 5.7 6.1 10 4.5 6.1 1.6 1 1 0 1 1 1 0 Macoilin family MT-A70 PF05063.14 KDO24540.1 - 4.4e-27 95.1 0.0 6.1e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.15 KDO24540.1 - 0.0043 16.7 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 N6-adenineMlase PF10237.9 KDO24540.1 - 0.031 14.1 0.0 0.086 12.6 0.0 1.6 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase UPF0020 PF01170.18 KDO24540.1 - 0.15 11.7 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Clat_adaptor_s PF01217.20 KDO24541.1 - 1.7e-17 63.7 0.2 2e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4024 PF13216.6 KDO24541.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) mRNA_cap_enzyme PF01331.19 KDO24542.1 - 1.2e-15 57.9 0.0 1.8e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KDO24542.1 - 0.00043 20.9 0.0 0.0026 18.4 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain zf_CCCH_4 PF18345.1 KDO24542.1 - 0.00051 20.0 6.2 0.001 19.0 6.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KDO24542.1 - 0.00059 19.7 6.5 0.0011 18.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DNA_ligase_A_M PF01068.21 KDO24542.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain MHYT PF03707.16 KDO24543.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.3 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat TauE PF01925.19 KDO24543.1 - 1.7 8.2 9.1 0.29 10.7 1.2 2.0 1 1 0 2 2 2 0 Sulfite exporter TauE/SafE DUF4118 PF13493.6 KDO24543.1 - 1.9 8.3 17.5 0.14 11.9 3.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) SPP PF06550.11 KDO24543.1 - 6.9 6.1 10.8 0.11 11.9 3.2 1.7 2 0 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease RMI1_N PF08585.12 KDO24544.1 - 5e-22 78.7 0.0 1.6e-18 67.3 0.0 2.2 1 1 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 KDO24544.1 - 2.1e-21 76.3 0.0 2.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Acetyltransf_3 PF13302.7 KDO24546.1 - 3.7e-23 82.7 0.1 4.8e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO24546.1 - 9.5e-07 29.1 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KDO24546.1 - 1.2e-06 28.3 0.4 3.6e-06 26.7 0.4 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO24546.1 - 0.00065 19.6 0.0 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 KDO24546.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RabGAP-TBC PF00566.18 KDO24547.1 - 2.5e-39 135.1 0.0 3.8e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Laminin_II PF06009.12 KDO24547.1 - 0.043 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Laminin Domain II DUF1319 PF07028.11 KDO24548.1 - 1.5 9.1 6.9 1.1 9.5 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) MIIP PF15734.5 KDO24548.1 - 2 7.8 7.7 4.6 6.6 6.8 1.9 1 1 1 2 2 2 0 Migration and invasion-inhibitory Mod_r PF07200.13 KDO24548.1 - 3.4 7.8 25.6 0.26 11.4 8.3 3.7 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein T3SS_basalb_I PF17001.5 KDO24548.1 - 5.8 7.6 9.0 2.5 8.7 0.1 3.6 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI DOT1 PF08123.13 KDO24549.1 - 3.5e-11 43.0 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KDO24549.1 - 2.1e-07 30.9 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO24549.1 - 4.5e-05 24.0 0.1 0.00016 22.2 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO24549.1 - 4.8e-05 24.0 0.0 0.00013 22.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO24549.1 - 0.035 13.9 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain VEFS-Box PF09733.9 KDO24549.1 - 0.18 11.6 1.3 0.44 10.3 1.3 1.7 1 0 0 1 1 1 0 VEFS-Box of polycomb protein dsDNA_bind PF01984.20 KDO24550.1 - 4.8e-25 88.0 10.6 5.4e-25 87.8 10.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain NDUF_B4 PF07225.12 KDO24550.1 - 0.78 9.7 3.4 1.5 8.8 0.7 1.9 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) TTL PF03133.15 KDO24551.1 - 3e-70 236.7 0.3 3e-70 236.7 0.3 3.0 4 0 0 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO24551.1 - 3.5e-06 26.5 0.0 0.00024 20.4 0.0 2.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO24551.1 - 6.7e-05 22.3 0.0 0.018 14.3 0.0 2.9 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KDO24551.1 - 0.0051 16.9 0.0 16 5.5 0.0 3.6 3 0 0 3 3 3 1 ATP-grasp domain Hce2 PF14856.6 KDO24551.1 - 0.051 13.9 0.9 15 5.9 0.1 2.8 3 0 0 3 3 3 0 Pathogen effector; putative necrosis-inducing factor Got1 PF04178.12 KDO24552.1 - 1.1e-20 74.2 16.7 1.1e-20 74.1 15.8 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family PAC4 PF16093.5 KDO24553.1 - 1.6e-18 66.6 0.0 2.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 SIR2 PF02146.17 KDO24554.1 - 2.8e-52 177.2 0.0 8e-52 175.7 0.0 1.8 2 0 0 2 2 2 1 Sir2 family ZZ PF00569.17 KDO24554.1 - 3.3e-05 23.6 10.4 3.3e-05 23.6 10.4 3.0 3 0 0 3 3 3 1 Zinc finger, ZZ type TPP_enzyme_M PF00205.22 KDO24554.1 - 0.00015 21.5 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KDO24554.1 - 0.035 13.9 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF592) WD40 PF00400.32 KDO24555.1 - 1.3e-43 146.1 21.0 5.5e-07 30.2 0.0 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO24555.1 - 4.5e-17 62.1 0.3 0.004 17.4 0.0 7.4 4 3 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO24555.1 - 1.1e-08 35.1 0.0 0.0054 16.6 0.0 4.0 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KDO24555.1 - 0.00045 20.1 0.2 22 5.2 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KDO24555.1 - 0.0007 18.4 0.2 0.022 13.4 0.1 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO24555.1 - 0.014 14.4 0.1 11 4.8 0.0 3.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KDO24555.1 - 0.037 12.0 0.0 0.58 8.1 0.0 2.2 2 0 0 2 2 2 0 IKI3 family WD40_like PF17005.5 KDO24555.1 - 0.12 11.7 0.0 5.9 6.1 0.0 2.6 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KDO24556.1 - 2.2e-11 44.1 5.3 0.00018 22.2 0.0 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO24556.1 - 4.8e-05 22.5 0.0 0.00012 21.2 0.0 1.5 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KDO24556.1 - 0.0007 19.9 0.0 2.6 8.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L24e PF01246.20 KDO24557.1 - 6.3e-27 93.6 0.2 1.6e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e DUF775 PF05603.12 KDO24557.1 - 0.013 15.0 0.2 0.015 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) HAD_SAK_2 PF18143.1 KDO24557.1 - 0.026 14.8 0.3 0.031 14.6 0.3 1.2 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins CTP_transf_like PF01467.26 KDO24557.1 - 0.04 14.1 1.2 0.72 10.0 0.9 2.0 1 1 1 2 2 2 0 Cytidylyltransferase-like DUF2058 PF09831.9 KDO24557.1 - 2 8.5 10.7 2.9 8.0 10.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Methyltransf_25 PF13649.6 KDO24558.1 - 1.1e-12 48.5 0.4 5.9e-12 46.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO24558.1 - 4.2e-11 42.9 0.3 5.5e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO24558.1 - 2.3e-10 40.4 0.1 3.1e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO24558.1 - 3.7e-09 37.1 0.0 9.6e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO24558.1 - 1.1e-06 28.5 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KDO24558.1 - 1.1e-05 25.4 0.4 1.9e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO24558.1 - 2e-05 24.1 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KDO24558.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KDO24558.1 - 0.00013 22.6 0.1 0.00035 21.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KDO24558.1 - 0.00022 20.2 0.1 0.0003 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KDO24558.1 - 0.00083 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KDO24558.1 - 0.0025 17.6 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KDO24558.1 - 0.0028 17.0 0.1 0.0043 16.4 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PRMT5_C PF17286.2 KDO24558.1 - 0.0079 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain TehB PF03848.14 KDO24558.1 - 0.0087 15.5 0.7 0.032 13.6 0.7 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 KDO24558.1 - 0.016 15.3 0.1 0.03 14.4 0.1 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KDO24558.1 - 0.026 15.5 0.0 0.053 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KDO24558.1 - 0.029 14.2 0.1 0.057 13.3 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 KDO24558.1 - 0.054 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KDO24558.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 KDO24558.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ASF1_hist_chap PF04729.13 KDO24559.1 - 2.5e-69 232.1 0.0 3.1e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone 7tm_2 PF00002.24 KDO24560.1 - 2.1e-14 53.4 12.3 1.6e-13 50.6 12.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KDO24560.1 - 1e-11 44.6 5.2 1.3e-11 44.2 5.2 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KDO24560.1 - 0.1 11.9 3.8 0.2 11.0 3.9 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CcmD PF04995.14 KDO24561.1 - 0.0038 17.3 2.0 0.016 15.3 1.0 2.3 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) TMEM51 PF15345.6 KDO24561.1 - 0.0097 15.8 0.2 0.014 15.2 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Rhabdo_glycop PF00974.18 KDO24561.1 - 0.018 13.5 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Miga PF10265.9 KDO24561.1 - 0.063 12.3 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Mitoguardin SKG6 PF08693.10 KDO24561.1 - 0.076 12.4 1.2 0.14 11.6 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LST1 PF05083.13 KDO24561.1 - 0.078 13.3 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 LST-1 protein DUF4448 PF14610.6 KDO24561.1 - 0.079 12.7 0.1 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Ashwin PF15323.6 KDO24561.1 - 0.089 12.8 0.7 0.12 12.4 0.7 1.2 1 0 0 1 1 1 0 Developmental protein DUF4381 PF14316.6 KDO24561.1 - 0.12 12.7 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KDO24561.1 - 0.13 13.1 0.4 0.25 12.2 0.4 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_glycop PF01528.16 KDO24561.1 - 0.21 10.4 1.1 0.27 10.1 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PDE8 PF08629.10 KDO24561.1 - 1.8 8.6 6.4 0.38 10.8 1.9 2.2 2 0 0 2 2 2 0 PDE8 phosphodiesterase EamA PF00892.20 KDO24562.1 - 5.1e-05 23.5 11.9 8.6e-05 22.7 11.9 1.4 1 1 0 1 1 1 1 EamA-like transporter family EamA PF00892.20 KDO24563.1 - 0.008 16.4 10.3 0.012 15.8 10.2 1.3 1 1 0 1 1 1 1 EamA-like transporter family MoeA_C PF03454.15 KDO24563.1 - 0.17 12.1 0.4 4.4 7.5 0.1 2.2 1 1 1 2 2 2 0 MoeA C-terminal region (domain IV) IU_nuc_hydro PF01156.19 KDO24567.1 - 2.6e-36 125.7 3.5 3.7e-36 125.3 3.5 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AAA PF00004.29 KDO24568.1 - 4.5e-35 120.9 0.0 1e-34 119.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO24568.1 - 3.1e-08 33.5 0.0 9.2e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO24568.1 - 1.7e-06 28.1 0.2 8.3e-06 25.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO24568.1 - 8.3e-06 26.1 0.2 0.016 15.5 0.0 3.1 1 1 2 3 3 3 2 AAA domain AAA_16 PF13191.6 KDO24568.1 - 0.0011 19.4 0.1 0.0079 16.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KDO24568.1 - 0.007 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KDO24568.1 - 0.028 14.1 0.1 0.65 9.7 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO24568.1 - 0.04 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.6 KDO24568.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KDO24568.1 - 0.044 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO24568.1 - 0.049 13.9 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO24568.1 - 0.055 13.4 0.1 8.8 6.2 0.0 2.4 1 1 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 KDO24568.1 - 0.07 13.2 0.0 0.35 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 KDO24568.1 - 0.071 12.9 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA+ lid domain AAA_18 PF13238.6 KDO24568.1 - 0.08 13.5 0.0 0.2 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KDO24568.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KDO24568.1 - 0.11 11.8 0.1 2.8 7.2 0.0 2.1 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 KDO24568.1 - 0.15 11.4 0.1 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Pkr1 PF08636.10 KDO24569.1 - 0.072 13.2 1.9 0.35 11.1 0.3 3.0 2 0 0 2 2 2 0 ER protein Pkr1 Histone PF00125.24 KDO24570.1 - 3.3e-52 176.3 2.6 3.7e-52 176.2 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KDO24570.1 - 9.5e-05 22.7 0.1 0.00014 22.1 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KDO24570.1 - 0.00022 21.8 1.2 0.00027 21.5 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO24570.1 - 0.0005 20.2 0.1 0.00099 19.2 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KDO24570.1 - 0.035 14.2 0.4 0.059 13.4 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KDO24570.1 - 0.052 13.8 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sel1 PF08238.12 KDO24571.1 - 1.6e-31 108.0 34.6 7.8e-05 23.2 0.1 10.2 10 1 0 10 10 10 7 Sel1 repeat TPR_17 PF13431.6 KDO24571.1 - 0.0049 17.2 0.4 3.2 8.3 0.2 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24571.1 - 0.016 14.8 1.1 0.18 11.5 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 KDO24571.1 - 1.4 9.7 0.0 1.4 9.7 0.0 8.0 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO24571.1 - 2.5 8.1 8.0 40 4.3 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HA PF03457.14 KDO24572.1 - 2.6e-20 72.5 0.1 6.5e-11 42.4 0.0 4.2 4 1 0 4 4 4 3 Helicase associated domain DnaJ PF00226.31 KDO24573.1 - 0.0017 18.4 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain ALMT PF11744.8 KDO24573.1 - 6.6 5.4 13.4 0.13 11.1 1.3 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter RINGv PF12906.7 KDO24574.1 - 1.5e-06 28.2 7.7 2.6e-06 27.5 7.7 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KDO24574.1 - 3.9e-05 23.9 8.6 6.6e-05 23.2 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KDO24574.1 - 0.022 14.8 1.8 0.041 13.9 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KDO24574.1 - 0.11 12.4 8.9 0.36 10.7 8.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KDO24574.1 - 0.32 10.9 6.0 0.49 10.3 6.0 1.3 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KDO24574.1 - 0.39 10.4 5.4 0.98 9.1 5.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KDO24574.1 - 0.4 11.0 6.6 0.66 10.3 6.6 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KDO24574.1 - 0.51 10.2 5.5 1.1 9.1 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD_4 PF16866.5 KDO24574.1 - 0.52 10.4 6.9 1.1 9.3 6.9 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KDO24574.1 - 2.8 8.3 6.7 6.5 7.2 6.7 1.7 1 0 0 1 1 1 0 RING-like domain EI24 PF07264.11 KDO24575.1 - 0.0025 18.1 2.4 0.0088 16.3 2.4 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PHD_4 PF16866.5 KDO24575.1 - 0.16 12.1 3.6 0.31 11.1 3.6 1.5 1 1 0 1 1 1 0 PHD-finger DUF2157 PF09925.9 KDO24575.1 - 0.44 10.3 0.1 0.44 10.3 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) RINGv PF12906.7 KDO24576.1 - 0.006 16.7 6.0 0.014 15.5 6.0 1.7 1 0 0 1 1 1 1 RING-variant domain Bac_export_2 PF01312.19 KDO24576.1 - 0.5 9.5 3.2 2.7 7.1 3.2 1.9 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF3450 PF11932.8 KDO24577.1 - 0.0014 18.0 2.4 0.0014 18.0 2.4 5.3 3 1 2 5 5 5 2 Protein of unknown function (DUF3450) DUF1192 PF06698.11 KDO24577.1 - 0.96 9.5 12.3 0.88 9.7 0.2 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DASH_Dad4 PF08650.10 KDO24577.1 - 2 8.4 7.6 21 5.2 0.1 4.6 6 0 0 6 6 6 0 DASH complex subunit Dad4 GAS PF13851.6 KDO24577.1 - 6.2 6.1 76.1 0.012 15.0 15.6 5.5 4 1 0 5 5 5 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KDO24577.1 - 7.6 5.3 72.8 0.87 8.4 5.4 4.6 3 1 0 4 4 4 0 Spc7 kinetochore protein ZYG-11_interact PF05884.12 KDO24577.1 - 9.3 5.6 6.6 3.2 7.1 1.2 2.6 2 0 0 2 2 2 0 Interactor of ZYG-11 CxC6 PF18721.1 KDO24579.1 - 0.27 11.5 23.9 1.5 9.2 7.4 4.2 1 1 3 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 KDO24580.1 - 4.4e-06 26.9 21.5 0.0027 17.9 6.0 4.1 1 1 2 3 3 3 3 CxC6 like cysteine cluster associated with KDZ transposases RRM_1 PF00076.22 KDO24583.1 - 2.1e-27 94.7 0.0 2.2e-15 56.2 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO24583.1 - 6.1e-05 22.8 0.0 0.039 13.8 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KDO24583.1 - 0.00011 22.3 0.0 0.0023 18.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif HalX PF08663.10 KDO24583.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 HalX domain DUF5392 PF17370.2 KDO24584.1 - 0.17 11.9 1.3 0.34 11.0 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5392) Aldedh PF00171.22 KDO24585.1 - 1.4e-107 360.0 0.0 1.6e-107 359.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KDO24585.1 - 0.077 12.0 0.3 0.3 10.1 0.3 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) adh_short_C2 PF13561.6 KDO24586.1 - 6.5e-66 222.2 2.3 7.6e-66 222.0 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO24586.1 - 7.1e-49 165.9 0.7 8.8e-49 165.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO24586.1 - 1.1e-09 38.5 1.4 1.9e-09 37.7 1.3 1.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KDO24586.1 - 0.087 11.8 0.3 0.26 10.2 0.2 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KDO24586.1 - 0.091 12.1 0.5 0.16 11.2 0.5 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GATase PF00117.28 KDO24587.1 - 2.3e-15 56.9 0.0 3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KDO24587.1 - 0.00058 19.7 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Histone PF00125.24 KDO24589.1 - 5e-20 72.2 0.2 6.2e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KDO24589.1 - 0.00021 21.7 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KDO24589.1 - 0.0014 18.9 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KDO24589.1 - 0.0021 18.1 0.1 0.0025 17.9 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Histone_H2A_C PF16211.5 KDO24590.1 - 7.1e-19 67.3 4.2 2e-18 65.8 4.2 1.8 1 1 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KDO24590.1 - 7.2e-16 58.7 0.0 9.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KDO24590.1 - 0.00013 22.1 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Kelch_5 PF13854.6 KDO24591.1 - 1.3e-24 85.7 3.7 7.5e-06 25.8 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KDO24591.1 - 7.9e-21 73.8 6.7 2.6e-05 24.1 0.0 6.5 5 2 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KDO24591.1 - 3.9e-20 71.6 11.6 0.00011 22.4 0.1 7.3 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO24591.1 - 1.1e-15 57.3 1.3 1.9e-05 24.8 0.0 5.8 4 2 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KDO24591.1 - 1.6e-08 34.0 0.3 0.35 10.5 0.0 6.0 5 2 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KDO24591.1 - 5.9e-07 29.2 4.4 0.00062 19.6 0.0 4.7 5 0 0 5 5 5 2 Kelch motif RAG2 PF03089.14 KDO24591.1 - 0.00013 21.1 0.0 2.8 6.8 0.0 3.6 2 1 1 3 3 3 2 Recombination activating protein 2 PQQ_3 PF13570.6 KDO24591.1 - 0.026 15.0 1.4 48 4.6 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Myb_DNA-binding PF00249.31 KDO24592.1 - 2.3e-11 43.7 7.7 6.1e-06 26.3 1.4 3.4 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO24592.1 - 4.7e-10 39.6 1.1 0.00011 22.3 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KDO24592.1 - 0.041 14.0 0.2 0.075 13.1 0.2 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAM184 PF15665.5 KDO24593.1 - 1.5e-23 83.7 31.7 1.5e-23 83.7 31.7 8.2 1 1 7 8 8 8 4 Family with sequence similarity 184, A and B DUF4806 PF16064.5 KDO24593.1 - 0.07 13.4 2.7 0.26 11.6 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) DUF2865 PF11064.8 KDO24593.1 - 4.5 7.7 6.1 0.75 10.2 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2865) RAMP4 PF06624.12 KDO24595.1 - 4.4e-20 71.5 0.0 4.8e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Perm-CXXC PF15629.6 KDO24597.1 - 1.9 8.8 13.8 4.5 7.6 0.2 4.0 4 0 0 4 4 4 0 Permuted single zf-CXXC unit PI3_PI4_kinase PF00454.27 KDO24599.1 - 1.3e-37 129.9 0.0 1.7e-28 100.1 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DEP PF00610.21 KDO24599.1 - 3.4e-06 27.0 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PI3Ka PF00613.20 KDO24599.1 - 0.054 12.9 0.1 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HSF_DNA-bind PF00447.17 KDO24601.1 - 4.5e-15 56.0 0.0 7.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding BUD22 PF09073.10 KDO24601.1 - 0.0019 17.6 11.1 0.0021 17.5 11.1 1.1 1 0 0 1 1 1 1 BUD22 DUF3874 PF12990.7 KDO24601.1 - 0.0083 16.4 0.1 0.09 13.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknonw function from B. Theta Gene description (DUF3874) CNDH2_C PF16858.5 KDO24601.1 - 0.0083 16.0 6.8 0.0095 15.8 6.8 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3245 PF11595.8 KDO24601.1 - 0.033 14.7 6.4 0.43 11.1 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Cwf_Cwc_15 PF04889.12 KDO24601.1 - 0.068 12.9 12.5 0.1 12.3 12.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KDO24601.1 - 0.19 11.0 12.9 0.3 10.4 12.9 1.3 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 KDO24601.1 - 0.2 12.3 12.8 0.33 11.7 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nucleo_P87 PF07267.11 KDO24601.1 - 0.23 10.3 5.7 0.3 9.9 5.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.11 KDO24601.1 - 0.24 10.9 9.7 0.3 10.7 9.7 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 KDO24601.1 - 0.26 10.4 23.1 0.4 9.8 23.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 KDO24601.1 - 0.26 11.5 15.9 0.32 11.2 15.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Afi1 PF07792.12 KDO24601.1 - 0.33 11.4 7.6 0.46 11.0 7.6 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Paf1 PF03985.13 KDO24601.1 - 0.89 8.5 17.7 1.1 8.2 17.7 1.1 1 0 0 1 1 1 0 Paf1 TERB2 PF15101.6 KDO24601.1 - 0.93 9.5 4.0 1.3 9.0 4.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Nop14 PF04147.12 KDO24601.1 - 1.6 6.9 16.6 1.8 6.7 16.6 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 KDO24601.1 - 2.4 8.4 9.2 3.4 8.0 9.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1682 PF07946.14 KDO24601.1 - 7.2 5.7 10.8 9.8 5.3 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HECA PF15353.6 KDO24602.1 - 0.083 13.1 6.4 2.4 8.5 0.5 2.9 2 1 1 3 3 3 0 Headcase protein family homologue Axin_b-cat_bind PF08833.10 KDO24602.1 - 7.9 6.7 7.2 8.9 6.5 1.5 2.8 2 2 0 2 2 2 0 Axin beta-catenin binding domain Cytokin_check_N PF10407.9 KDO24603.1 - 6e-05 22.9 0.0 0.0032 17.4 0.0 2.2 1 1 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Metallophos PF00149.28 KDO24605.1 - 7.6e-34 118.0 0.3 1.2e-33 117.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KDO24605.1 - 4.3e-25 87.8 0.0 9e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 KDO24605.1 - 4.7e-13 48.3 0.2 0.00015 21.4 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO24605.1 - 1.3e-09 37.4 0.2 0.0065 16.5 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24605.1 - 1.2e-07 31.3 2.9 0.01 15.5 0.5 3.9 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 KDO24605.1 - 2.1e-05 24.3 2.6 0.11 12.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO24605.1 - 0.00075 19.6 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24605.1 - 0.0011 19.5 0.3 0.94 10.2 0.0 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO24605.1 - 0.016 15.6 0.1 0.059 13.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO24605.1 - 0.27 11.4 1.2 18 5.5 0.1 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat FYVE PF01363.21 KDO24606.1 - 4.3e-06 26.8 6.5 8.8e-06 25.8 6.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO24606.1 - 0.0023 18.1 2.5 0.0046 17.2 2.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger FIST PF08495.10 KDO24606.1 - 0.029 14.4 0.0 0.093 12.7 0.0 1.8 1 0 0 1 1 1 0 FIST N domain Siva PF05458.12 KDO24606.1 - 0.036 13.8 1.9 0.075 12.7 1.9 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) HA PF03457.14 KDO24607.1 - 2.4e-45 152.7 11.0 9.9e-12 45.0 0.1 5.4 6 0 0 6 6 6 5 Helicase associated domain zf-RING_2 PF13639.6 KDO24609.1 - 7.2e-05 23.0 10.8 7.2e-05 23.0 10.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KDO24609.1 - 0.0001 22.1 9.8 0.00021 21.1 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO24609.1 - 0.0011 18.6 5.7 0.0042 16.8 5.7 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO24609.1 - 0.0019 18.2 7.6 0.004 17.2 7.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 KDO24609.1 - 0.14 12.1 8.2 0.32 10.9 8.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 KDO24609.1 - 0.17 11.9 10.7 0.57 10.2 10.7 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KDO24609.1 - 0.2 11.8 10.0 0.53 10.5 10.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KDO24609.1 - 0.23 11.4 11.3 0.91 9.4 11.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO24609.1 - 0.32 10.9 9.4 0.72 9.8 9.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO24609.1 - 0.9 9.9 10.5 4 7.8 10.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Gcd10p PF04189.13 KDO24610.1 - 4.9e-60 203.2 0.0 1.4e-59 201.7 0.0 1.8 2 0 0 2 2 2 1 Gcd10p family Fucose_iso_N2 PF07882.12 KDO24610.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain FYVE PF01363.21 KDO24611.1 - 9.9e-16 57.6 6.3 9.9e-16 57.6 6.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO24611.1 - 0.31 11.3 4.9 0.71 10.1 4.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Transthyretin PF00576.21 KDO24612.1 - 1.3e-34 119.2 0.0 1.5e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Caerin_1 PF07440.12 KDO24612.1 - 0.17 12.0 2.4 0.33 11.1 2.4 1.5 1 0 0 1 1 1 0 Caerin 1 protein WD40 PF00400.32 KDO24613.1 - 0.0015 19.3 10.1 0.1 13.5 0.4 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat AT_hook PF02178.19 KDO24613.1 - 0.014 15.2 74.5 0.46 10.5 3.8 7.9 7 0 0 7 7 7 0 AT hook motif DUF1676 PF07898.13 KDO24614.1 - 0.096 12.7 0.8 0.13 12.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) MFS_1 PF07690.16 KDO24615.1 - 6.7e-08 31.8 43.1 9.7e-08 31.3 36.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily PGI PF00342.19 KDO24615.1 - 0.019 13.6 0.1 0.029 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase Glyoxalase PF00903.25 KDO24616.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.16 KDO24617.1 - 1.1e-06 27.9 8.5 1.2e-06 27.8 8.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.15 KDO24617.1 - 1.5 9.3 6.1 2.2 8.8 2.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2207 PF09972.9 KDO24617.1 - 4.1 6.1 6.8 8.7 5.0 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.16 KDO24619.1 - 5.3e-05 22.3 17.1 5.3e-05 22.3 17.1 3.7 1 1 2 4 4 4 2 Major Facilitator Superfamily zf-piccolo PF05715.13 KDO24622.1 - 0.12 12.5 7.8 0.21 11.7 7.8 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger FYVE_2 PF02318.16 KDO24622.1 - 0.17 12.1 7.4 0.28 11.4 7.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4637 PF15470.6 KDO24622.1 - 0.35 10.6 3.9 0.6 9.8 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-UDP PF14569.6 KDO24622.1 - 0.4 10.8 2.8 0.63 10.2 2.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-B_box PF00643.24 KDO24622.1 - 0.77 10.0 11.8 2.6 8.3 11.8 1.9 1 1 0 1 1 1 0 B-box zinc finger DUF2318 PF10080.9 KDO24622.1 - 1.1 9.4 4.6 3 8.0 4.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) FYVE_2 PF02318.16 KDO24623.1 - 1e-05 25.7 5.3 1.6e-05 25.1 5.3 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger PHD PF00628.29 KDO24623.1 - 4.1 7.4 9.7 9.2 6.3 9.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.6 KDO24624.1 - 0.038 14.1 7.1 0.082 13.0 7.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 KDO24624.1 - 0.051 13.8 9.1 0.081 13.1 9.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 KDO24624.1 - 1.1 9.4 12.8 2.4 8.4 12.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger FYVE_2 PF02318.16 KDO24625.1 - 0.0011 19.1 8.1 0.0022 18.2 8.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger MFS_1 PF07690.16 KDO24626.1 - 0.00057 18.9 35.3 0.001 18.1 35.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO24626.1 - 0.0015 17.5 1.9 0.0015 17.5 1.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TMEM100 PF16311.5 KDO24626.1 - 0.12 12.0 0.7 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2304 PF10066.9 KDO24626.1 - 0.39 11.0 0.1 0.39 11.0 0.1 3.1 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) MFS_1 PF07690.16 KDO24627.1 - 1.1e-12 47.6 27.6 1.6e-12 47.0 27.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5337 PF17272.2 KDO24628.1 - 0.18 11.7 3.6 0.43 10.4 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5337) MFS_1 PF07690.16 KDO24628.1 - 9.5 5.0 47.6 0.27 10.1 37.9 3.1 2 1 0 2 2 2 0 Major Facilitator Superfamily DUF2058 PF09831.9 KDO24632.1 - 0.015 15.5 0.4 0.015 15.5 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) AP_endonuc_2 PF01261.24 KDO24633.1 - 1.9e-06 27.5 0.3 3.3e-06 26.7 0.3 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MRP-S33 PF08293.11 KDO24634.1 - 2.3e-06 27.8 0.4 5.7e-06 26.5 0.4 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF4115 PF13464.6 KDO24634.1 - 0.098 12.9 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) Ribul_P_3_epim PF00834.19 KDO24635.1 - 7e-56 188.8 0.0 8.4e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Ricin_B_lectin PF00652.22 KDO24637.1 - 1.7e-22 80.0 4.4 4.5e-13 49.5 1.3 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 KDO24637.1 - 1.3e-05 24.9 0.0 0.00037 20.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RicinB_lectin_2 PF14200.6 KDO24637.1 - 0.00015 22.4 10.3 0.032 15.0 0.3 4.3 1 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like IQ PF00612.27 KDO24638.1 - 0.00091 18.8 0.3 0.0061 16.3 0.3 2.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Matrilin_ccoil PF10393.9 KDO24638.1 - 2.3 8.2 4.4 1.4 8.8 0.3 2.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin PhaG_MnhG_YufB PF03334.14 KDO24641.1 - 0.023 14.9 1.7 0.023 14.9 1.7 2.6 3 0 0 3 3 3 0 Na+/H+ antiporter subunit DUF1084 PF06454.11 KDO24642.1 - 7.4e-12 45.2 9.7 2.1e-11 43.7 9.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Ribosomal_S27e PF01667.17 KDO24643.1 - 0.076 12.7 1.1 0.24 11.1 1.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 FYVE_2 PF02318.16 KDO24644.1 - 0.078 13.2 2.5 0.15 12.2 2.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S27e PF01667.17 KDO24644.1 - 0.39 10.5 5.3 0.24 11.1 3.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 START PF01852.19 KDO24645.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 START domain CytadhesinP1 PF12378.8 KDO24645.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein Peptidase_A17 PF05380.13 KDO24645.1 - 0.12 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Pao retrotransposon peptidase zf-MYND PF01753.18 KDO24646.1 - 1.2e-07 31.7 13.7 1.2e-07 31.7 13.7 3.1 2 1 0 2 2 2 1 MYND finger SET PF00856.28 KDO24646.1 - 1.5e-06 28.7 0.0 5.9e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF5009 PF16401.5 KDO24647.1 - 0.0065 16.0 3.2 0.015 14.8 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5009) DUF1624 PF07786.12 KDO24647.1 - 0.44 10.1 15.6 0.01 15.4 8.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) RabGAP-TBC PF00566.18 KDO24648.1 - 2.4e-19 69.9 0.2 4.7e-19 68.9 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 KDO24648.1 - 0.00089 19.1 3.9 0.0031 17.4 0.2 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KDO24648.1 - 0.035 14.0 0.9 0.1 12.5 0.2 2.2 2 0 0 2 2 2 0 F-box domain SAM_2 PF07647.17 KDO24649.1 - 0.02 15.0 0.2 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO24649.1 - 0.15 12.6 0.1 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) p12I PF12233.8 KDO24650.1 - 0.059 13.9 2.3 8.5 7.0 0.0 3.2 3 0 0 3 3 3 0 Human adult T cell leukemia/lymphoma virus protein Hydrolase_4 PF12146.8 KDO24653.1 - 0.00055 19.3 0.0 0.063 12.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KDO24653.1 - 0.00067 19.3 0.0 0.0017 17.9 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KDO24653.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2817 PF10994.8 KDO24654.1 - 1.8e-84 284.1 0.0 2e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 KDO24654.1 - 0.007 15.5 0.0 0.03 13.4 0.0 1.9 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_19 PF14559.6 KDO24655.1 - 1.7e-16 60.5 18.7 5.7e-06 26.8 0.2 6.9 5 2 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO24655.1 - 2.5e-15 55.3 0.1 0.0071 16.5 0.0 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO24655.1 - 1.2e-14 53.2 18.6 0.0028 17.6 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO24655.1 - 2.1e-13 49.4 1.8 0.0052 16.6 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO24655.1 - 3.4e-12 46.1 33.3 0.0043 17.8 0.2 9.9 4 3 6 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24655.1 - 5.7e-09 36.5 38.7 8.8e-06 26.3 0.5 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24655.1 - 2.5e-08 33.5 0.0 5.3 6.8 0.0 6.6 6 1 0 6 6 6 1 TPR repeat TPR_12 PF13424.6 KDO24655.1 - 2.1e-07 31.2 20.6 0.05 13.9 0.1 7.5 6 3 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO24655.1 - 3.3e-07 30.2 0.1 3.4 8.3 0.0 6.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO24655.1 - 3.9e-06 27.2 9.9 0.13 12.9 0.0 7.2 8 2 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO24655.1 - 1.7e-05 25.0 5.4 0.059 13.6 0.4 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KDO24655.1 - 6.6e-05 23.0 18.8 0.007 16.5 0.4 5.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO24655.1 - 0.00037 20.3 6.3 3.4 7.9 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 KDO24655.1 - 0.0015 17.5 0.0 4.4 6.1 0.0 3.3 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 KDO24655.1 - 0.0027 17.4 10.5 0.024 14.4 0.6 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KDO24655.1 - 0.081 13.3 4.7 0.59 10.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO24655.1 - 1.5 9.6 0.0 1.5 9.6 0.0 6.5 7 0 0 7 7 4 0 Tetratricopeptide repeat SET PF00856.28 KDO24656.1 - 2e-18 67.3 3.8 1e-17 65.1 0.1 3.2 2 1 0 2 2 2 1 SET domain PHD PF00628.29 KDO24656.1 - 1e-08 35.0 45.7 2.6e-05 24.0 12.1 4.6 4 2 0 4 4 4 3 PHD-finger AWS PF17907.1 KDO24656.1 - 0.0026 17.8 7.5 0.0026 17.8 7.5 3.5 2 1 1 3 3 3 1 AWS domain zf-PHD-like PF15446.6 KDO24656.1 - 0.1 12.2 30.2 0.03 14.0 5.0 4.3 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain NARP1 PF12569.8 KDO24656.1 - 3.9 6.3 9.5 6.2 5.6 9.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MOSC_N PF03476.16 KDO24657.1 - 2.2e-32 111.5 0.0 3.7e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KDO24657.1 - 4.2e-19 68.9 0.0 7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain RNase_HII PF01351.18 KDO24659.1 - 1.3e-52 178.6 0.0 1.5e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DSPc PF00782.20 KDO24661.1 - 2e-08 34.1 0.1 4e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO24661.1 - 1e-05 25.2 0.2 1.9e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KDO24661.1 - 0.0035 17.0 0.1 0.0051 16.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) FYVE PF01363.21 KDO24661.1 - 0.011 15.9 0.2 0.029 14.5 0.1 1.8 2 0 0 2 2 2 0 FYVE zinc finger GTP_EFTU PF00009.27 KDO24663.1 - 1.4e-58 197.7 0.1 2.3e-58 197.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KDO24663.1 - 3.5e-36 123.6 0.1 7.3e-36 122.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KDO24663.1 - 2e-32 111.1 0.0 4.3e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KDO24663.1 - 4.2e-27 94.0 0.0 1.6e-26 92.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KDO24663.1 - 2e-11 44.1 0.0 5.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KDO24663.1 - 1.8e-06 27.8 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KDO24663.1 - 1.6e-05 25.3 0.0 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KDO24663.1 - 0.0037 17.3 0.1 0.0088 16.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.13 KDO24663.1 - 0.012 15.7 0.2 0.89 9.7 0.0 3.2 4 0 0 4 4 4 0 Putative phosphatase (DUF442) AIG1 PF04548.16 KDO24663.1 - 0.016 14.5 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Leader_Trp PF08255.11 KDO24664.1 - 0.21 11.6 2.9 1.9 8.6 0.6 2.8 2 0 0 2 2 2 0 Trp-operon Leader Peptide Exo_endo_phos PF03372.23 KDO24665.1 - 1.2e-06 28.2 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GP70 PF17429.2 KDO24665.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Gene product 70 Tnp_22_dsRBD PF17490.2 KDO24667.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Sugarporin_N PF11471.8 KDO24668.1 - 0.0051 16.7 0.3 0.0098 15.8 0.3 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Nucleoporin_FG PF13634.6 KDO24669.1 - 6.2e-44 148.8 94.4 6.3e-08 33.4 22.1 10.4 4 3 5 9 9 9 9 Nucleoporin FG repeat region SDA1 PF05285.12 KDO24669.1 - 1.4 8.2 16.4 0.015 14.8 8.2 1.8 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 KDO24669.1 - 1.5 7.0 8.7 2.3 6.4 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KDO24669.1 - 2.4 6.3 15.4 3.4 5.8 15.4 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 KDO24669.1 - 8 6.7 10.5 8.5 6.6 9.1 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated Homeobox_KN PF05920.11 KDO24670.1 - 1.5e-16 60.0 0.6 4e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KDO24670.1 - 1.5e-08 34.4 0.1 3.2e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain RNase_PH PF01138.21 KDO24671.1 - 1.7e-36 125.7 0.1 2.2e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO24671.1 - 6.4e-07 29.3 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TCR PF03638.15 KDO24672.1 - 4.8e-17 62.0 56.0 3.3e-10 40.1 25.8 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain NHL PF01436.21 KDO24673.1 - 9.2e-10 38.1 12.7 0.015 15.3 0.0 5.8 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 KDO24673.1 - 0.0024 17.5 0.7 4.5 6.8 0.0 3.9 2 2 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Vac7 PF12751.7 KDO24673.1 - 0.018 14.5 0.6 0.025 14.1 0.6 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 SBBP PF06739.11 KDO24673.1 - 0.15 12.1 5.7 2 8.5 0.0 4.4 4 1 0 4 4 4 0 Beta-propeller repeat DUF3619 PF12279.8 KDO24673.1 - 0.22 11.9 0.0 0.44 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) US22 PF02393.16 KDO24673.1 - 2.4 8.4 4.2 5.9 7.2 0.3 3.0 3 1 0 3 3 3 0 US22 like Peptidase_C12 PF01088.21 KDO24674.1 - 7.7e-60 202.2 0.0 8.8e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Methyltransf_16 PF10294.9 KDO24675.1 - 1.4e-21 77.0 0.0 1.9e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase TPR_9 PF13371.6 KDO24675.1 - 0.12 12.5 3.0 4.6 7.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PrmA PF06325.13 KDO24675.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PGAP1 PF07819.13 KDO24678.1 - 0.00017 21.4 0.1 0.00045 20.0 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KDO24678.1 - 0.00062 20.4 0.2 0.00062 20.4 0.2 3.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.14 KDO24678.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KDO24678.1 - 0.063 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KDO24678.1 - 0.12 11.6 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 KDO24679.1 - 2.6e-80 269.6 0.0 8.9e-40 136.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24679.1 - 2.9e-79 266.0 0.0 1e-39 136.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4444 PF14563.6 KDO24679.1 - 0.12 12.1 0.4 8 6.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) IQ PF00612.27 KDO24680.1 - 1.5e-12 46.1 16.9 0.00023 20.6 0.1 4.6 4 0 0 4 4 4 4 IQ calmodulin-binding motif LRR_8 PF13855.6 KDO24682.1 - 0.017 14.8 0.4 3.9 7.3 0.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat LRRNT PF01462.18 KDO24682.1 - 0.059 13.0 0.6 0.14 11.9 0.6 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain MFS_1 PF07690.16 KDO24683.1 - 8.8e-09 34.7 44.4 5.2e-05 22.3 17.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KDO24683.1 - 3.5e-08 33.3 9.9 3.5e-08 33.3 9.9 4.0 4 1 0 4 4 4 2 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KDO24684.1 - 7.8e-12 44.8 29.6 7.8e-12 44.8 29.6 2.9 2 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KDO24684.1 - 6.6e-11 42.2 15.0 1.4e-10 41.1 6.2 3.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF1129 PF06570.11 KDO24684.1 - 0.044 13.3 0.2 0.15 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4075 PF13294.6 KDO24685.1 - 0.11 12.6 0.1 6.7 6.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4075) MFS_1 PF07690.16 KDO24686.1 - 4.4e-18 65.3 60.4 9.5e-13 47.8 36.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 KDO24686.1 - 3.1e-10 40.0 9.1 3.1e-10 40.0 9.1 4.6 4 1 0 4 4 4 2 Ion channel regulatory protein UNC-93 DUF2177 PF09945.9 KDO24686.1 - 0.0012 18.9 1.6 0.0012 18.9 1.6 2.5 2 1 1 3 3 3 1 Predicted membrane protein (DUF2177) Fimbrial_K88 PF02432.15 KDO24686.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Fimbrial, major and minor subunit BT1 PF03092.16 KDO24687.1 - 1.9e-17 62.7 15.7 1.2e-15 56.7 5.0 3.1 2 1 0 2 2 2 2 BT1 family Dynein_C PF18199.1 KDO24690.1 - 1.1e-107 359.9 0.0 1.5e-107 359.4 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KDO24690.1 - 1.6e-53 180.9 0.0 2.6e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO24690.1 - 1.8e-45 153.8 0.0 4.8e-45 152.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KDO24691.1 - 1.2e-145 484.6 0.0 1.8e-144 480.7 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO24691.1 - 5.1e-138 460.5 13.2 1.7e-137 458.8 13.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO24691.1 - 5e-105 350.5 0.9 1.8e-103 345.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO24691.1 - 3.5e-88 294.4 1.0 3.5e-88 294.4 1.0 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO24691.1 - 7.9e-84 279.7 0.3 7.3e-79 263.5 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KDO24691.1 - 9.3e-48 163.0 6.4 2.6e-47 161.5 6.4 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KDO24691.1 - 4.9e-31 107.5 0.0 1.8e-30 105.7 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO24691.1 - 2.1e-23 82.4 0.0 8.7e-23 80.4 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO24691.1 - 2.7e-22 79.3 0.1 3.1e-06 27.3 0.0 6.6 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO24691.1 - 2.1e-08 34.5 0.6 0.29 11.4 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 KDO24691.1 - 1.3e-06 28.9 0.6 1.3 9.4 0.0 5.7 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KDO24691.1 - 3.7e-05 22.9 0.2 0.29 10.2 0.1 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 KDO24691.1 - 0.00013 22.4 1.0 6.4 7.1 0.0 5.0 4 0 0 4 4 3 1 AAA ATPase domain Sigma54_activat PF00158.26 KDO24691.1 - 0.0012 18.6 0.9 4.1 7.1 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_30 PF13604.6 KDO24691.1 - 0.0012 18.6 1.5 3.3 7.4 0.1 3.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KDO24691.1 - 0.0023 18.3 0.5 17 5.8 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 KDO24691.1 - 0.0026 18.3 0.0 0.51 10.9 0.0 3.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KDO24691.1 - 0.0036 16.7 0.2 0.83 9.0 0.0 3.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KDO24691.1 - 0.0074 15.7 0.9 3.1 7.1 0.0 3.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KDO24691.1 - 0.088 11.9 0.0 1.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DUF853 PF05872.12 KDO24691.1 - 0.2 10.2 8.0 0.85 8.1 0.1 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) AAA_25 PF13481.6 KDO24691.1 - 0.27 10.8 3.1 11 5.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF1765 PF08578.10 KDO24692.1 - 2.9e-16 60.1 6.3 8.8e-16 58.5 6.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DJ-1_PfpI PF01965.24 KDO24693.1 - 0.00011 22.1 0.1 0.00043 20.1 0.1 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KDO24693.1 - 0.052 12.6 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Ldh_2 PF02615.14 KDO24694.1 - 7.1e-88 295.0 2.1 8e-88 294.8 2.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase BPL_N PF09825.9 KDO24695.1 - 2.8e-06 26.7 0.0 4.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_5 PF13507.6 KDO24695.1 - 3.9e-05 22.9 0.0 5.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 KDO24695.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain C2 PF00168.30 KDO24696.1 - 4.6e-61 203.5 3.1 4.8e-14 52.5 0.1 6.7 5 1 0 5 5 5 5 C2 domain FerI PF08151.12 KDO24696.1 - 4.6e-05 23.4 0.0 0.0002 21.3 0.0 2.1 1 0 0 1 1 1 1 FerI (NUC094) domain RIBIOP_C PF04950.12 KDO24696.1 - 0.16 11.4 0.5 0.35 10.3 0.5 1.5 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal C2 PF00168.30 KDO24697.1 - 4.5e-20 71.9 0.0 1e-09 38.6 0.0 4.1 4 0 0 4 4 4 3 C2 domain DnaJ PF00226.31 KDO24698.1 - 6.7e-12 45.4 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 KDO24699.1 - 7.1e-50 169.8 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24699.1 - 1.1e-47 162.5 0.0 1.6e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 KDO24699.1 - 1.4e-07 31.9 0.1 6.2e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO24699.1 - 5.7e-06 26.3 0.1 1.7e-05 24.9 0.0 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KDO24699.1 - 9.3e-06 24.7 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 KDO24699.1 - 4.9e-05 23.8 0.0 9.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.23 KDO24699.1 - 0.0012 18.8 0.3 0.0012 18.8 0.3 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO24699.1 - 0.0024 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_8 PF15409.6 KDO24699.1 - 0.0053 17.0 0.4 0.012 15.9 0.4 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO24699.1 - 0.0076 16.6 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 KDO24699.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO24699.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain EF-hand_7 PF13499.6 KDO24700.1 - 2.1e-19 69.7 0.1 2.9e-10 40.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO24700.1 - 1e-18 65.4 2.4 9.2e-08 31.1 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 KDO24700.1 - 2.2e-14 52.2 4.2 3.7e-05 23.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO24700.1 - 2.1e-13 49.0 3.3 6.6e-05 22.5 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KDO24700.1 - 1.6e-10 40.7 1.8 0.00048 19.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO24700.1 - 0.0016 18.7 0.2 0.54 10.6 0.0 2.7 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO24700.1 - 0.0045 16.9 2.6 0.53 10.3 0.0 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Rcd1 PF04078.13 KDO24701.1 - 1.5e-128 427.6 2.5 1.7e-128 427.4 2.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like MatE PF01554.18 KDO24702.1 - 7e-21 74.6 17.6 1.1e-19 70.7 13.3 2.5 2 0 0 2 2 2 2 MatE PseudoU_synth_1 PF01416.20 KDO24703.1 - 8e-17 61.7 0.0 6.3e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 KDO24703.1 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Ribosomal_L14e PF01929.17 KDO24704.1 - 1.1e-28 99.5 6.4 1.1e-28 99.5 6.4 1.4 1 1 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KDO24704.1 - 0.06 13.3 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 KOW motif Ribosomal_L5e PF17144.4 KDO24705.1 - 2.4e-81 271.5 1.5 4.8e-81 270.5 1.5 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KDO24705.1 - 4.6e-29 101.2 5.4 4.6e-29 101.2 5.4 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region REV PF00424.18 KDO24706.1 - 0.031 14.3 0.4 2.7 8.1 0.0 2.9 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) DUF4180 PF13788.6 KDO24706.1 - 0.18 11.8 2.3 0.23 11.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4180) HsbA PF12296.8 KDO24706.1 - 2.7 8.4 9.9 0.48 10.9 4.0 2.6 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Globin PF00042.22 KDO24707.1 - 0.26 11.9 1.6 1.2 9.7 1.6 2.0 1 1 0 1 1 1 0 Globin Rab_bind PF16704.5 KDO24709.1 - 0.0057 16.7 3.9 0.0057 16.7 3.9 2.3 1 1 1 2 2 2 1 Rab binding domain Rx_N PF18052.1 KDO24709.1 - 0.011 15.9 4.3 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Rx N-terminal domain NOG1 PF06858.14 KDO24709.1 - 0.07 12.9 0.3 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) S6OS1 PF15676.5 KDO24709.1 - 0.089 11.3 0.7 0.1 11.1 0.7 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Macoilin PF09726.9 KDO24709.1 - 0.32 9.5 10.9 0.62 8.5 10.9 1.4 1 1 0 1 1 1 0 Macoilin family DUF4061 PF13270.6 KDO24709.1 - 0.67 10.3 9.8 0.87 9.9 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF641 PF04859.12 KDO24709.1 - 3.2 8.1 9.7 2.2 8.7 3.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 KDO24709.1 - 3.2 6.7 9.6 9.1 5.3 9.6 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 KDO24709.1 - 4.3 7.8 8.4 7.3 7.0 1.0 2.9 2 1 0 2 2 2 0 Csm1 N-terminal domain End3 PF12761.7 KDO24709.1 - 4.8 7.3 9.5 3.6 7.7 6.8 1.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF3450 PF11932.8 KDO24709.1 - 8.9 5.5 17.6 4.5 6.5 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Ribosomal_L30_N PF08079.12 KDO24710.1 - 2.9e-23 81.9 11.3 2.9e-23 81.9 11.3 2.1 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KDO24710.1 - 1.2e-20 73.1 2.9 1.2e-20 73.1 2.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Pkinase PF00069.25 KDO24711.1 - 7.9e-68 228.7 0.0 1.1e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24711.1 - 4.1e-31 108.2 1.0 8e-29 100.7 1.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO24711.1 - 2.8e-06 26.8 0.7 4.8e-06 26.1 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO24711.1 - 0.00029 20.3 0.2 0.032 13.5 0.1 2.6 2 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KDO24711.1 - 0.00052 18.9 0.1 0.0011 17.8 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO24711.1 - 0.00076 18.5 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KDO24711.1 - 0.0028 17.3 0.2 0.0048 16.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO24711.1 - 0.021 14.7 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 KDO24711.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Ribo_biogen_C PF04034.13 KDO24712.1 - 5.5e-51 171.6 0.0 8.6e-51 171.0 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KDO24712.1 - 5.5e-10 38.9 0.6 9.5e-10 38.1 0.6 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RNA_pol_I_A49 PF06870.12 KDO24713.1 - 1.1e-70 238.5 1.9 1.3e-70 238.3 1.9 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Phage_fiber_2 PF03406.13 KDO24713.1 - 0.0043 16.6 0.6 0.013 15.0 0.6 1.8 1 0 0 1 1 1 1 Phage tail fibre repeat BcrAD_BadFG PF01869.20 KDO24713.1 - 0.075 12.5 0.3 7.5 6.0 0.1 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family EIF_2_alpha PF07541.12 KDO24713.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit cNMP_binding PF00027.29 KDO24714.1 - 1e-49 166.5 1.4 6e-15 55.1 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO24714.1 - 6.4e-25 87.8 58.5 2.2e-16 59.9 9.0 4.3 4 0 0 4 4 4 4 Ion transport protein zf-B_box PF00643.24 KDO24714.1 - 8.2e-05 22.7 5.6 8.2e-05 22.7 5.6 2.3 2 0 0 2 2 2 1 B-box zinc finger Fer2_3 PF13085.6 KDO24714.1 - 0.037 14.0 0.8 0.087 12.8 0.8 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ion_trans PF00520.31 KDO24715.1 - 1.8e-36 125.6 7.4 2.1e-36 125.4 7.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO24715.1 - 4e-11 42.7 9.8 4e-11 42.7 9.8 2.4 2 1 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KDO24715.1 - 0.041 12.6 3.7 0.051 12.2 3.0 1.5 1 1 0 1 1 1 0 Polycystin cation channel Lig_chan PF00060.26 KDO24715.1 - 0.069 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel DUF2614 PF11023.8 KDO24715.1 - 4.7 7.3 5.6 0.73 10.0 0.6 2.2 2 1 0 2 2 2 0 Zinc-ribbon containing domain Ion_trans PF00520.31 KDO24716.1 - 0.056 12.7 1.0 0.081 12.1 1.0 1.3 1 0 0 1 1 1 0 Ion transport protein Oxygenase-NA PF09859.9 KDO24716.1 - 0.25 10.9 0.5 1.2 8.6 0.3 1.8 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA Ion_trans PF00520.31 KDO24717.1 - 1e-25 90.4 3.0 1.3e-25 90.1 3.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO24717.1 - 7.6e-14 51.4 3.9 9.8e-14 51.1 0.3 2.1 2 0 0 2 2 2 1 Ion channel EF-hand_6 PF13405.6 KDO24717.1 - 0.026 14.4 0.1 3.3 7.9 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KDO24717.1 - 0.026 14.0 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KDO24717.1 - 0.14 12.7 2.0 0.57 10.7 1.4 2.3 1 1 1 2 2 2 0 EF-hand domain pair DUF294_C PF10335.9 KDO24717.1 - 0.51 10.1 4.6 1 9.1 0.9 2.7 3 0 0 3 3 3 0 Putative nucleotidyltransferase substrate binding domain Ion_trans PF00520.31 KDO24718.1 - 1.6e-36 125.8 4.1 2.1e-36 125.4 4.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO24718.1 - 9.4e-10 38.3 6.8 1e-09 38.2 3.7 2.6 2 1 0 2 2 2 1 Ion channel Sensor PF13796.6 KDO24718.1 - 0.0033 17.5 0.9 0.0033 17.5 0.9 2.9 2 1 1 3 3 3 1 Putative sensor IRK PF01007.20 KDO24718.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DUF3096 PF11295.8 KDO24718.1 - 0.15 11.7 1.5 0.35 10.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) PIN_10 PF18478.1 KDO24718.1 - 0.16 12.2 0.8 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 PIN like domain cNMP_binding PF00027.29 KDO24719.1 - 1.3e-52 175.8 1.1 5.1e-14 52.1 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO24719.1 - 3.7e-28 98.4 71.4 1.7e-15 57.0 10.3 4.7 4 1 0 4 4 4 4 Ion transport protein GTP_EFTU PF00009.27 KDO24720.1 - 4.3e-37 127.6 0.0 1.8e-36 125.6 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KDO24720.1 - 9.4e-19 67.5 0.0 3.1e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KDO24720.1 - 1.1e-14 54.1 0.2 1.1e-14 54.1 0.2 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KDO24720.1 - 1.5e-07 31.7 13.6 6.4e-06 26.5 0.4 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO24720.1 - 1e-06 28.8 0.1 6.1e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KDO24720.1 - 0.00095 19.4 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KDO24720.1 - 0.0061 16.4 0.2 0.045 13.5 0.0 2.6 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KDO24720.1 - 0.017 15.4 2.2 0.024 14.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.22 KDO24721.1 - 1e-15 57.3 0.0 1.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KDO24721.1 - 1e-05 26.0 13.8 1e-05 26.0 13.8 4.3 2 2 2 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 KDO24721.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif GST_N_2 PF13409.6 KDO24722.1 - 3.7e-14 52.8 0.0 2.6e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO24722.1 - 6.5e-12 45.6 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO24722.1 - 7.4e-12 45.5 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO24722.1 - 0.00018 21.6 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO24722.1 - 0.00026 21.1 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO24722.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PCRF PF03462.18 KDO24723.1 - 2.6e-58 197.1 0.8 3.9e-58 196.5 0.1 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KDO24723.1 - 2.4e-37 127.4 1.2 2.4e-37 127.4 1.2 1.9 2 0 0 2 2 2 1 RF-1 domain Mrr_N PF14338.6 KDO24723.1 - 0.27 11.4 1.1 0.8 9.9 1.1 1.8 1 0 0 1 1 1 0 Mrr N-terminal domain Suc_Fer-like PF06999.12 KDO24724.1 - 2e-28 99.6 0.0 2.3e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like EF-hand_7 PF13499.6 KDO24725.1 - 1.1e-10 41.8 0.2 3.5e-10 40.2 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO24725.1 - 1.2e-10 40.5 0.2 5.1e-05 22.9 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KDO24725.1 - 3.9e-09 35.4 0.9 0.0023 17.3 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KDO24725.1 - 1e-05 24.7 3.0 0.1 12.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO24725.1 - 3.6e-05 23.5 2.3 0.018 14.9 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO24725.1 - 0.00078 19.7 0.3 0.0047 17.2 0.0 2.5 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region TUDOR_5 PF18359.1 KDO24725.1 - 0.0019 17.9 0.1 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 KDO24725.1 - 0.0021 18.5 4.2 0.0039 17.6 3.3 1.9 2 0 0 2 2 1 1 Agenet domain KASH_CCD PF14662.6 KDO24725.1 - 0.093 12.6 11.9 2.5 7.9 11.9 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH EF-hand_4 PF12763.7 KDO24725.1 - 0.15 12.0 0.3 10 6.2 0.3 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand FAM76 PF16046.5 KDO24725.1 - 0.52 9.6 2.9 0.84 8.9 2.9 1.4 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 KDO24725.1 - 0.76 9.8 5.4 0.6 10.2 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CEP63 PF17045.5 KDO24725.1 - 3.2 7.6 13.9 2.1 8.2 5.6 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF4337 PF14235.6 KDO24725.1 - 3.3 7.8 9.3 5.5 7.1 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF724 PF05266.14 KDO24725.1 - 5 6.9 8.7 24 4.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KDO24725.1 - 5.9 5.7 16.3 37 3.1 5.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Beta_helix PF13229.6 KDO24730.1 - 1.6e-06 28.0 3.9 3.4e-05 23.7 1.6 1.8 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 KDO24730.1 - 0.11 11.8 2.6 5.1 6.3 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1565) NosD PF05048.13 KDO24730.1 - 0.23 10.7 2.0 0.85 8.8 2.1 1.6 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) cNMP_binding PF00027.29 KDO24731.1 - 3.3e-21 75.2 0.1 3.1e-11 43.2 0.1 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ubiquitin PF00240.23 KDO24731.1 - 1.8e-09 37.2 0.1 4.4e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family C2 PF00168.30 KDO24732.1 - 4.9e-96 315.9 2.5 7.2e-21 74.4 0.0 8.8 9 0 0 9 9 9 8 C2 domain FerI PF08151.12 KDO24732.1 - 0.00046 20.2 0.0 0.0017 18.4 0.0 2.0 1 0 0 1 1 1 1 FerI (NUC094) domain C2 PF00168.30 KDO24733.1 - 4.8e-89 293.4 0.1 1.2e-19 70.5 0.0 8.4 8 0 0 8 8 8 7 C2 domain FerI PF08151.12 KDO24733.1 - 0.00051 20.1 0.0 0.0022 18.0 0.0 2.1 1 0 0 1 1 1 1 FerI (NUC094) domain Ferlin_C PF16165.5 KDO24733.1 - 0.01 15.8 0.2 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 Ferlin C-terminus AIF-MLS PF14962.6 KDO24733.1 - 0.087 12.8 1.1 0.16 11.9 1.1 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MYCBPAP PF14646.6 KDO24735.1 - 1.7e-27 96.5 0.4 6.2e-27 94.6 0.0 2.2 2 1 0 2 2 2 1 MYCBP-associated protein family PGK PF00162.19 KDO24735.1 - 2.9e-13 49.5 0.0 1.3e-05 24.4 0.0 3.1 3 0 0 3 3 3 2 Phosphoglycerate kinase RNA_polI_A34 PF08208.11 KDO24735.1 - 3 7.9 18.2 0.014 15.5 2.5 2.9 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 RNA_pol_Rpc4 PF05132.14 KDO24735.1 - 4.1 7.8 11.2 7.2 7.0 1.7 3.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 Ysc84 PF04366.12 KDO24736.1 - 7.5e-33 113.0 0.2 1.2e-32 112.4 0.2 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 KDO24736.1 - 2.7e-11 43.4 7.2 2.7e-11 43.4 7.2 3.1 3 0 0 3 3 3 1 FYVE zinc finger DZR PF12773.7 KDO24736.1 - 0.0016 18.4 1.5 0.0016 18.4 1.5 4.2 3 1 0 3 3 3 1 Double zinc ribbon FYVE_2 PF02318.16 KDO24736.1 - 0.0032 17.7 2.8 0.0032 17.7 2.8 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Prok-RING_2 PF14445.6 KDO24736.1 - 7.3 6.8 12.5 0.48 10.6 4.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Vps26 PF03643.15 KDO24737.1 - 2.1e-100 335.3 0.1 2.4e-100 335.1 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KDO24737.1 - 5.8e-08 32.9 0.3 0.027 14.5 0.0 3.3 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain EF-hand_7 PF13499.6 KDO24738.1 - 2.4e-14 53.5 0.0 6.8e-11 42.5 0.1 4.8 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO24738.1 - 4.5e-13 47.7 0.0 5.4e-05 22.5 0.2 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KDO24738.1 - 8.6e-12 44.0 0.0 6.7e-05 22.5 0.2 5.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.6 KDO24738.1 - 5.5e-08 32.0 0.2 0.00036 19.9 0.1 4.3 5 0 0 5 5 5 2 EF hand IQ PF00612.27 KDO24738.1 - 3.5e-05 23.2 5.5 0.002 17.8 0.5 7.3 7 1 1 8 8 8 2 IQ calmodulin-binding motif EF-hand_9 PF14658.6 KDO24738.1 - 0.00015 22.0 0.0 16 5.9 0.0 5.3 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 KDO24738.1 - 0.00079 19.2 0.5 0.0055 16.5 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain pair zf-C2H2_4 PF13894.6 KDO24738.1 - 0.023 15.5 0.1 0.11 13.4 0.1 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Sec7_N PF12783.7 KDO24738.1 - 0.045 13.7 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal OrsD PF12013.8 KDO24738.1 - 1 9.9 5.4 0.92 10.0 2.0 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D PH PF00169.29 KDO24739.1 - 2.8e-19 69.6 0.1 4.5e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO24739.1 - 3.6e-05 24.1 0.5 8.6e-05 22.9 0.5 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO24739.1 - 0.00051 20.1 0.0 0.0027 17.8 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KDO24739.1 - 0.022 15.1 0.1 0.3 11.5 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 KDO24739.1 - 0.041 14.3 0.1 0.1 13.0 0.0 1.7 1 1 1 2 2 2 0 Plant pleckstrin homology-like region PH_13 PF16652.5 KDO24739.1 - 0.27 11.1 0.8 0.27 11.0 0.1 1.5 2 0 0 2 2 2 0 Pleckstrin homology domain DLIC PF05783.11 KDO24740.1 - 7.7e-37 127.2 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 KDO24740.1 - 8.1e-06 26.1 0.0 5.8e-05 23.3 0.0 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Thioredoxin_12 PF18400.1 KDO24740.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain G-alpha PF00503.20 KDO24740.1 - 0.036 13.2 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KDO24740.1 - 0.048 13.6 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_27 PF13514.6 KDO24740.1 - 0.065 12.8 1.5 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO24740.1 - 0.066 13.6 0.1 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 KDO24740.1 - 0.074 12.6 0.0 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Ras family RNase_PH PF01138.21 KDO24741.1 - 1.5e-16 61.1 0.0 2.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO24741.1 - 2.1e-10 40.5 0.1 4.5e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 WW PF00397.26 KDO24742.1 - 6.9e-06 26.1 0.8 6.9e-06 26.1 0.8 3.1 3 0 0 3 3 3 2 WW domain IQ PF00612.27 KDO24742.1 - 8.3 6.5 33.8 0.034 13.9 3.0 5.2 5 0 0 5 5 5 0 IQ calmodulin-binding motif An_peroxidase PF03098.15 KDO24743.1 - 0.082 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase ATG16 PF08614.11 KDO24744.1 - 0.0007 19.9 10.5 0.0015 18.8 6.1 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) PH PF00169.29 KDO24744.1 - 0.0045 17.5 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 PH domain LEA_1 PF03760.15 KDO24744.1 - 0.071 13.8 0.8 0.071 13.8 0.8 2.6 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Peptidase_C1 PF00112.23 KDO24745.1 - 9.4e-23 81.4 1.2 1.2e-22 81.1 1.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease VbhA PF18495.1 KDO24745.1 - 0.08 12.8 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Antitoxin VbhA Peptidase_C1 PF00112.23 KDO24746.1 - 1.4e-37 129.9 0.2 1.9e-37 129.5 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease DUF4229 PF14012.6 KDO24746.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Peptidase_C1 PF00112.23 KDO24747.1 - 1.4e-36 126.7 0.5 1.7e-36 126.4 0.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease SafA PF17073.5 KDO24747.1 - 0.17 11.9 0.2 0.3 11.1 0.2 1.4 1 0 0 1 1 1 0 Two-component-system connector protein Peptidase_C1 PF00112.23 KDO24748.1 - 3.9e-38 131.7 0.2 5.1e-38 131.4 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease CBM_19 PF03427.13 KDO24748.1 - 0.047 13.7 1.8 0.16 12.0 1.8 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DUF4229 PF14012.6 KDO24748.1 - 0.09 12.9 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Roc PF08477.13 KDO24749.1 - 1.4e-11 44.6 0.0 2.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO24749.1 - 1e-09 38.2 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KDO24749.1 - 0.00066 19.2 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Pkinase PF00069.25 KDO24750.1 - 2.2e-51 174.8 0.0 3e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24750.1 - 1.5e-48 165.4 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO24750.1 - 0.00022 20.6 0.6 0.00036 19.9 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO24750.1 - 0.00081 18.8 0.1 0.0012 18.2 0.1 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO24750.1 - 0.0055 16.7 1.1 0.011 15.6 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family SepZ PF06066.11 KDO24750.1 - 0.031 14.5 0.4 0.062 13.5 0.4 1.4 1 0 0 1 1 1 0 SepZ Haspin_kinase PF12330.8 KDO24750.1 - 0.067 12.1 0.1 0.094 11.6 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO24750.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO24752.1 - 1.4e-37 129.4 0.0 1.2e-24 87.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO24752.1 - 1.6e-34 119.4 0.0 2.5e-32 112.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO24752.1 - 0.0073 16.3 1.7 0.04 13.8 0.2 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO24752.1 - 0.025 14.0 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO24752.1 - 0.057 13.0 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KDO24752.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KDO24754.1 - 2e-50 171.6 0.0 2.7e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24754.1 - 1.7e-47 161.9 0.0 2.2e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO24754.1 - 2.4e-05 23.3 0.0 3.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO24754.1 - 0.028 14.4 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO24754.1 - 0.038 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KDO24754.1 - 0.049 13.3 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SK_channel PF03530.14 KDO24755.1 - 0.00027 20.9 0.3 0.0011 18.9 0.3 2.0 1 1 0 1 1 1 1 Calcium-activated SK potassium channel Lig_chan PF00060.26 KDO24755.1 - 0.00086 19.2 1.8 0.0021 17.9 0.1 2.1 1 1 1 2 2 2 2 Ligand-gated ion channel WDCP PF15390.6 KDO24756.1 - 0.01 14.3 1.5 0.13 10.6 0.1 2.2 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF3577 PF12101.8 KDO24756.1 - 0.22 11.3 0.0 0.5 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) Pkinase_Tyr PF07714.17 KDO24758.1 - 1.9e-51 174.9 0.0 3.3e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO24758.1 - 4.5e-50 170.5 0.0 1e-49 169.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KDO24758.1 - 1.3e-07 31.2 12.7 0.00048 19.8 0.2 5.3 4 1 1 5 5 5 2 Leucine rich repeat Pkinase_fungal PF17667.1 KDO24758.1 - 0.0011 17.9 0.1 0.0017 17.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_9 PF14580.6 KDO24758.1 - 0.0031 17.0 1.6 0.75 9.3 0.1 3.6 3 1 0 3 3 3 1 Leucine-rich repeat DUF325 PF03804.13 KDO24758.1 - 0.15 12.1 0.6 0.79 9.8 0.0 2.5 3 0 0 3 3 3 0 Viral proteins of unknown function LRR_4 PF12799.7 KDO24758.1 - 0.19 12.2 24.3 0.72 10.4 3.5 7.3 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) DUF484 PF04340.12 KDO24761.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 PADR1 PF08063.12 KDO24761.1 - 4 7.3 5.5 13 5.6 0.1 3.2 3 0 0 3 3 3 0 PADR1 (NUC008) domain GTP_EFTU PF00009.27 KDO24762.1 - 1.1e-57 194.8 0.0 1.4e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KDO24762.1 - 8.1e-29 100.2 0.0 1.5e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KDO24762.1 - 8.6e-17 61.3 3.3 1.9e-16 60.2 3.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO24762.1 - 3.4e-05 23.9 0.1 7.3e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 KDO24762.1 - 0.017 14.7 0.3 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KDO24762.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 KDO24764.1 - 5.7e-52 176.7 0.0 7.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24764.1 - 3.7e-21 75.6 0.0 5.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO24764.1 - 4.9e-05 23.4 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KDO24764.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KDO24764.1 - 0.024 14.2 0.2 0.068 12.8 0.1 1.6 1 1 0 1 1 1 0 RIO1 family WD40 PF00400.32 KDO24765.1 - 4.2e-20 71.7 22.5 0.00039 21.2 0.9 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF485 PF04341.12 KDO24766.1 - 0.14 12.1 0.2 0.19 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Med6 PF04934.14 KDO24767.1 - 7.9e-36 122.8 1.8 1.2e-35 122.2 1.8 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Pinin_SDK_memA PF04696.13 KDO24768.1 - 3.1e-16 59.6 4.3 3.1e-16 59.6 4.3 3.7 3 2 1 4 4 4 1 pinin/SDK/memA/ protein conserved region SAP PF02037.27 KDO24768.1 - 4.7e-11 42.2 1.3 9.4e-11 41.2 1.3 1.5 1 0 0 1 1 1 1 SAP domain Peptidase_S8 PF00082.22 KDO24769.1 - 9.5e-42 143.3 12.7 1.5e-41 142.6 12.7 1.3 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 KDO24769.1 - 5.4e-06 26.7 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain AAA PF00004.29 KDO24770.1 - 3.7e-53 179.5 0.0 3e-40 137.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO24770.1 - 1.6e-10 41.4 0.3 0.045 14.0 0.0 4.0 2 2 1 4 4 4 3 AAA domain AAA_16 PF13191.6 KDO24770.1 - 1.2e-09 38.8 0.3 0.00075 19.9 0.1 3.0 2 1 1 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 KDO24770.1 - 3.3e-07 30.4 0.1 0.0037 17.3 0.1 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KDO24770.1 - 6.3e-07 29.3 0.0 0.0078 16.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 KDO24770.1 - 1e-06 28.6 0.1 0.068 12.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KDO24770.1 - 1.4e-06 28.6 0.0 2.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 KDO24770.1 - 2.8e-06 26.7 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Mg_chelatase PF01078.21 KDO24770.1 - 4.1e-06 26.3 0.5 0.0035 16.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KDO24770.1 - 4.7e-06 26.0 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KDO24770.1 - 2.3e-05 24.6 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KDO24770.1 - 3.9e-05 23.4 0.1 9.8e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 KDO24770.1 - 6.1e-05 22.7 0.1 0.00059 19.6 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 KDO24770.1 - 7.1e-05 22.3 0.1 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 KDO24770.1 - 8.7e-05 22.3 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO24770.1 - 9e-05 21.8 0.1 0.016 14.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 KDO24770.1 - 0.00012 21.5 0.1 5.6 6.3 0.0 3.9 3 1 1 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 KDO24770.1 - 0.00014 22.2 0.0 0.072 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KDO24770.1 - 0.00018 21.3 0.0 0.13 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KDO24770.1 - 0.00024 21.1 1.5 0.33 10.9 0.1 3.3 3 2 1 4 4 3 2 NACHT domain ABC_tran PF00005.27 KDO24770.1 - 0.00027 21.4 0.1 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 KDO24770.1 - 0.00049 20.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KDO24770.1 - 0.00079 19.0 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KDO24770.1 - 0.00083 19.4 0.0 0.054 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KDO24770.1 - 0.00091 19.2 0.2 1.1 9.1 0.2 3.7 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KDO24770.1 - 0.0015 18.4 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KDO24770.1 - 0.0021 17.6 0.1 0.97 8.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 KDO24770.1 - 0.0033 17.0 3.6 2.3 7.8 0.3 3.8 3 1 1 4 4 4 1 AAA domain AAA_18 PF13238.6 KDO24770.1 - 0.0047 17.5 0.0 0.99 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO24770.1 - 0.0073 16.0 0.1 3.2 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KDO24770.1 - 0.011 15.7 0.0 0.066 13.1 0.0 2.2 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_19 PF13245.6 KDO24770.1 - 0.017 15.5 2.3 1.7 8.9 0.1 3.5 3 1 1 4 4 4 0 AAA domain ResIII PF04851.15 KDO24770.1 - 0.018 15.1 0.0 9.6 6.2 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KDO24770.1 - 0.018 15.3 0.0 2.1 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KDO24770.1 - 0.024 15.1 0.0 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KDO24770.1 - 0.03 14.1 0.0 6.1 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO24770.1 - 0.039 13.1 0.2 0.59 9.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KDO24770.1 - 0.051 13.3 0.2 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KDO24770.1 - 0.057 13.1 0.0 6.9 6.3 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 KDO24770.1 - 0.068 12.6 0.0 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 KDO24770.1 - 0.074 12.3 0.3 4.6 6.4 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CDC48_N PF02359.18 KDO24770.1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.9 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Parvo_NS1 PF01057.17 KDO24770.1 - 0.2 10.7 0.0 12 4.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 KDO24770.1 - 0.21 11.3 0.9 24 4.7 0.1 3.1 2 2 2 4 4 4 0 DEAD/DEAH box helicase Isochorismatase PF00857.20 KDO24771.1 - 1e-27 97.4 0.0 1.3e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 KDO24772.1 - 1.7e-24 87.0 0.1 2.4e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family CDC45 PF02724.14 KDO24773.1 - 4.7e-170 567.0 0.6 5.8e-169 563.4 0.6 1.9 1 1 0 1 1 1 1 CDC45-like protein RAB3GAP2_N PF14655.6 KDO24774.1 - 0.025 13.9 0.4 0.039 13.2 0.1 1.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Sec39 PF08314.11 KDO24774.1 - 0.04 12.4 0.0 0.06 11.8 0.0 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Sugar_tr PF00083.24 KDO24776.1 - 1.2e-50 172.8 22.8 1.5e-50 172.4 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO24776.1 - 2.2e-38 132.1 40.4 6.3e-28 97.7 22.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KDO24776.1 - 0.00033 20.1 6.5 0.00033 20.1 6.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KDO24776.1 - 0.0013 17.3 2.5 0.0023 16.4 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PLDc_2 PF13091.6 KDO24777.1 - 1.4e-17 63.8 0.0 1.7e-07 31.2 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KDO24777.1 - 3.2e-05 23.9 2.7 0.0087 16.2 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Use1 PF09753.9 KDO24778.1 - 3.2e-05 23.8 0.0 4e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 EAV_GP5 PF15981.5 KDO24778.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.5 1 1 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus CCSMST1 PF15013.6 KDO24778.1 - 0.25 11.5 0.5 1.2 9.3 0.1 2.0 2 0 0 2 2 2 0 CCSMST1 family CX9C PF16860.5 KDO24780.1 - 3.9e-05 23.6 0.2 4.8e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 KDO24780.1 - 0.0046 17.1 0.5 0.0055 16.9 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein zf-CCHC_6 PF15288.6 KDO24780.1 - 0.033 14.0 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle UPF0203 PF05254.12 KDO24780.1 - 0.058 13.6 0.8 0.45 10.8 0.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Sdh5 PF03937.16 KDO24781.1 - 2e-20 72.5 0.1 3.2e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Tim17 PF02466.19 KDO24782.1 - 1.5e-08 35.0 3.5 1.9e-08 34.7 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KDO24782.1 - 0.065 13.6 4.8 0.17 12.3 3.7 2.0 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 RWP-RK PF02042.15 KDO24783.1 - 1.1e-14 54.1 0.7 1.7e-14 53.5 0.7 1.3 1 0 0 1 1 1 1 RWP-RK domain DSBA PF01323.20 KDO24784.1 - 2.2e-16 60.2 0.0 2.9e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DSBA PF01323.20 KDO24785.1 - 1.3e-17 64.2 0.0 1.7e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RNA_pol_A_bac PF01000.26 KDO24786.1 - 2.2e-29 102.1 0.0 4.4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KDO24786.1 - 5.4e-23 80.2 0.0 8.5e-23 79.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 KDO24786.1 - 0.034 14.3 1.8 0.097 12.9 1.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Sds3 PF08598.11 KDO24788.1 - 0.00016 21.8 2.7 0.00061 19.9 2.7 1.6 1 1 1 2 2 2 1 Sds3-like fn3_PAP PF17808.1 KDO24788.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Use1 PF09753.9 KDO24789.1 - 0.00021 21.1 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2927 PF11150.8 KDO24789.1 - 0.0055 16.8 0.9 0.0068 16.5 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2927) Nnf1 PF03980.14 KDO24789.1 - 0.012 16.0 2.3 0.018 15.4 2.3 1.3 1 0 0 1 1 1 0 Nnf1 DUF3394 PF11874.8 KDO24789.1 - 0.03 14.0 0.4 0.036 13.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) AdoHcyase PF05221.17 KDO24790.1 - 2.4e-144 480.0 0.0 2.8e-144 479.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KDO24790.1 - 1.8e-81 271.9 2.8 2.7e-81 271.4 2.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KDO24790.1 - 9e-09 34.9 0.7 1.6e-08 34.2 0.7 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KDO24790.1 - 0.00018 21.2 0.4 0.00038 20.0 0.4 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KDO24790.1 - 0.012 15.9 0.7 0.063 13.5 0.7 2.1 1 1 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 KDO24790.1 - 0.017 14.8 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 KDO24790.1 - 0.049 13.7 0.6 0.12 12.4 0.6 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KDO24790.1 - 0.076 13.5 0.3 0.22 12.0 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_L21p PF00829.21 KDO24791.1 - 1.9e-31 108.3 2.6 2.3e-31 108.1 2.6 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Fibrillarin PF01269.17 KDO24792.1 - 5.3e-96 320.1 0.0 6.8e-96 319.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KDO24792.1 - 0.00019 21.2 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KDO24792.1 - 0.0067 16.2 0.0 0.0095 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AA_permease PF00324.21 KDO24793.1 - 6.8e-33 114.0 42.9 9.8e-33 113.4 42.9 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO24793.1 - 6.9e-33 114.1 48.0 9.8e-33 113.6 48.0 1.2 1 0 0 1 1 1 1 Amino acid permease bZIP_2 PF07716.15 KDO24795.1 - 0.033 14.3 2.1 0.072 13.2 2.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 KDO24795.1 - 0.084 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TRAF_BIRC3_bd PF16673.5 KDO24795.1 - 0.13 12.1 1.8 0.27 11.0 1.8 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain bZIP_2 PF07716.15 KDO24797.1 - 0.0013 18.7 5.3 0.0027 17.8 5.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO24797.1 - 0.002 18.2 3.9 0.0039 17.3 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Surfac_D-trimer PF09006.11 KDO24798.1 - 0.01 15.7 0.1 0.039 13.9 0.1 2.0 1 1 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Myosin_tail_1 PF01576.19 KDO24798.1 - 0.016 13.0 0.8 0.022 12.6 0.8 1.1 1 0 0 1 1 1 0 Myosin tail bZIP_2 PF07716.15 KDO24798.1 - 0.027 14.6 1.3 0.05 13.7 1.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KDO24798.1 - 0.047 13.8 3.3 0.084 13.0 3.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor PS-DH PF14765.6 KDO24800.1 - 0.056 12.7 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Mt_ATP-synt_D PF05873.12 KDO24802.1 - 1.9e-15 57.0 0.6 2.5e-15 56.6 0.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Vps51 PF08700.11 KDO24802.1 - 0.034 14.2 0.1 0.16 12.0 0.1 2.2 1 1 2 3 3 3 0 Vps51/Vps67 Hrs_helical PF12210.8 KDO24802.1 - 0.09 13.3 1.5 0.98 10.0 0.2 2.6 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate HIG_1_N PF04588.13 KDO24803.1 - 7.8e-19 67.6 1.4 1.1e-18 67.2 1.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SNARE PF05739.19 KDO24804.1 - 1.5e-13 50.5 0.6 1.5e-13 50.5 0.6 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KDO24804.1 - 0.0001 22.0 15.3 0.014 15.1 0.1 2.7 3 1 0 3 3 3 2 Syntaxin Syntaxin-6_N PF09177.11 KDO24804.1 - 0.028 14.9 3.6 0.043 14.4 1.2 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4698 PF15769.5 KDO24804.1 - 0.19 10.8 4.6 0.26 10.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) AI-2E_transport PF01594.16 KDO24804.1 - 0.51 9.4 6.2 0.11 11.6 0.5 2.1 2 0 0 2 2 2 0 AI-2E family transporter PCRF PF03462.18 KDO24804.1 - 1.1 9.1 7.3 0.32 10.9 3.0 2.0 2 0 0 2 2 2 0 PCRF domain Corona_S2 PF01601.16 KDO24804.1 - 1.3 7.4 13.2 0.32 9.4 5.7 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein DUF16 PF01519.16 KDO24804.1 - 1.4 9.4 13.5 1.2 9.7 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Rtt106 PF08512.12 KDO24805.1 - 8.9e-28 96.6 0.0 8.7e-24 83.8 0.0 2.4 2 0 0 2 2 2 2 Histone chaperone Rttp106-like SSrecog PF03531.14 KDO24805.1 - 9.7e-25 86.3 0.0 2.6e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KDO24805.1 - 2.2e-11 44.0 0.0 1.6e-10 41.2 0.0 2.5 3 0 0 3 3 3 1 POB3-like N-terminal PH domain PH_TFIIH PF08567.11 KDO24805.1 - 0.017 15.4 0.2 0.065 13.6 0.0 2.0 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain YL1 PF05764.13 KDO24805.1 - 0.27 11.3 22.9 0.43 10.7 22.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 KDO24805.1 - 4.4 5.8 25.1 6 5.3 25.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KDO24805.1 - 6.3 4.9 21.1 8.5 4.5 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KDO24807.1 - 6.4e-06 24.8 0.9 7.6e-06 24.5 0.9 1.2 1 0 0 1 1 1 1 CDC45-like protein LTXXQ PF07813.12 KDO24807.1 - 0.01 16.6 0.6 0.01 16.6 0.6 2.9 2 1 1 3 3 3 0 LTXXQ motif family protein PsbX PF06596.11 KDO24807.1 - 2.3 8.3 4.8 5.4 7.1 4.8 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF4148 PF13663.6 KDO24807.1 - 2.9 8.1 8.8 3.2 8.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) LRR_4 PF12799.7 KDO24808.1 - 4.6e-13 49.1 11.8 1.7e-06 28.3 1.2 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO24808.1 - 2.3e-07 30.5 7.2 9.7e-07 28.5 6.2 2.6 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 KDO24808.1 - 1.2e-06 28.1 1.5 0.09 12.9 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.6 KDO24808.1 - 2e-05 24.2 10.1 0.0011 18.5 1.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KDO24808.1 - 0.17 12.6 2.9 7.2 7.6 0.1 3.9 2 2 0 2 2 2 0 Leucine Rich Repeat Exonuc_VII_L PF02601.15 KDO24808.1 - 0.7 9.4 7.8 1.1 8.7 7.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.8 KDO24808.1 - 1.1 8.4 7.3 1.6 7.8 7.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Voltage_CLC PF00654.20 KDO24809.1 - 1.5e-91 307.3 15.2 1.5e-91 307.3 15.2 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KDO24809.1 - 1.9e-06 28.2 0.0 9.5e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 CBS domain TAT_signal PF10518.9 KDO24809.1 - 0.69 9.9 10.2 0.19 11.6 4.4 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DUF2516 PF10724.9 KDO24809.1 - 3.2 8.1 7.2 0.38 11.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Nup35_RRM PF05172.13 KDO24810.1 - 6.7e-14 51.7 0.1 4.1e-13 49.1 0.1 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KDO24810.1 - 5.6e-10 39.1 0.0 1.4e-09 37.8 0.1 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif TatD_DNase PF01026.21 KDO24811.1 - 6.2e-50 169.9 0.0 7.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Peroxidase_2 PF01328.17 KDO24813.1 - 5.1e-35 121.7 0.0 6.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EFhand_Ca_insen PF08726.10 KDO24813.1 - 0.028 14.5 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Ank_5 PF13857.6 KDO24814.1 - 3.5e-05 24.0 0.2 7.3e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO24814.1 - 0.00018 22.0 0.1 0.00035 21.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24814.1 - 0.0012 19.4 0.1 0.0037 17.8 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24814.1 - 0.0055 17.1 0.1 0.016 15.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 KDO24814.1 - 0.038 14.4 0.2 0.11 13.0 0.2 1.8 1 0 0 1 1 1 0 Ankyrin repeat TMEM151 PF14857.6 KDO24815.1 - 0.13 11.1 0.2 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 TMEM151 family DUF3165 PF11364.8 KDO24815.1 - 0.34 11.3 11.6 0.62 10.4 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3165) DAGK_prokar PF01219.19 KDO24815.1 - 0.47 10.3 4.6 1.2 9.1 1.2 2.4 2 1 0 2 2 2 0 Prokaryotic diacylglycerol kinase DUF1192 PF06698.11 KDO24816.1 - 0.0033 17.5 1.2 0.009 16.0 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) RPS31 PF17067.5 KDO24816.1 - 0.018 15.2 5.6 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S31e NDK PF00334.19 KDO24817.1 - 1.3e-29 103.0 0.0 1.2e-28 99.8 0.0 2.1 2 0 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 KDO24817.1 - 0.0013 18.5 0.2 0.0033 17.2 0.2 1.6 1 1 0 1 1 1 1 DUF1126 PH-like domain DUF1249 PF06853.12 KDO24817.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) MORN PF02493.20 KDO24818.1 - 6.7e-40 132.7 41.5 1.9e-07 30.5 1.2 8.4 8 0 0 8 8 8 8 MORN repeat Polysacc_synt_C PF14667.6 KDO24820.1 - 0.0015 18.6 2.8 0.0021 18.1 2.8 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF5504 PF17608.2 KDO24820.1 - 0.044 13.9 0.7 0.08 13.0 0.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5504) DUF2537 PF10801.8 KDO24820.1 - 0.055 13.7 4.1 0.097 12.9 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) ABC1 PF03109.16 KDO24821.1 - 3.7e-33 114.2 0.0 6.8e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family DPBB_1 PF03330.18 KDO24822.1 - 2.4e-05 24.5 0.6 6.6e-05 23.1 0.6 1.7 1 1 0 1 1 1 1 Lytic transglycolase PrsW-protease PF13367.6 KDO24823.1 - 3.2e-20 72.4 4.5 3.2e-20 72.4 4.5 2.0 1 1 0 1 1 1 1 PrsW family intramembrane metalloprotease SporV_AA PF12164.8 KDO24824.1 - 0.12 12.7 0.0 0.71 10.3 0.0 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AA LSM PF01423.22 KDO24825.1 - 3.6e-15 55.4 0.1 4.6e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO24825.1 - 0.012 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.9 KDO24825.1 - 0.062 13.2 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein IMPDH PF00478.25 KDO24826.1 - 3.7e-81 272.8 5.8 2.4e-80 270.2 5.8 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KDO24826.1 - 2.7e-05 23.4 1.5 5.1e-05 22.5 1.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KDO24826.1 - 0.065 12.7 0.9 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein Aldolase PF01081.19 KDO24826.1 - 0.073 12.5 0.7 0.27 10.6 0.1 2.0 1 1 1 2 2 2 0 KDPG and KHG aldolase dCache_3 PF14827.6 KDO24826.1 - 0.098 12.3 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase PAP2_C PF14360.6 KDO24826.1 - 0.13 12.8 0.1 0.25 11.9 0.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily C-terminal NBD_C PF17042.5 KDO24826.1 - 0.62 10.5 4.1 0.49 10.9 0.2 2.5 2 1 1 3 3 3 0 Nucleotide-binding C-terminal domain DUF4660 PF15559.6 KDO24827.1 - 0.03 14.6 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) PITH PF06201.13 KDO24828.1 - 1.7e-35 122.5 0.0 1.9e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 PITH domain NAM-associated PF14303.6 KDO24829.1 - 3.8 8.2 7.2 16 6.2 0.7 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain AA_permease_2 PF13520.6 KDO24831.1 - 1.4e-10 40.6 34.9 2e-10 40.1 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO24831.1 - 7.7e-07 28.1 33.8 1.1e-06 27.6 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3615 PF12274.8 KDO24831.1 - 0.19 12.3 0.1 0.33 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) AA_permease_2 PF13520.6 KDO24832.1 - 5.2e-05 22.3 17.1 6.7e-05 21.9 17.1 1.1 1 0 0 1 1 1 1 Amino acid permease PTS_EIIC PF02378.18 KDO24832.1 - 0.0022 17.1 1.5 0.0047 16.0 1.5 1.6 1 0 0 1 1 1 1 Phosphotransferase system, EIIC CTK3 PF12243.8 KDO24833.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 SLC35F PF06027.12 KDO24834.1 - 8.5e-57 192.9 19.4 9.8e-57 192.7 19.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KDO24834.1 - 4.9e-08 32.3 3.5 4.9e-08 32.3 3.5 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO24834.1 - 0.00089 19.4 10.1 0.00089 19.4 10.1 2.5 2 0 0 2 2 2 1 EamA-like transporter family DoxX_2 PF13564.6 KDO24834.1 - 0.013 15.6 4.1 0.057 13.5 4.1 2.2 1 0 0 1 1 1 0 DoxX-like family NAGLU PF05089.12 KDO24835.1 - 2.6e-132 440.8 2.4 3.6e-132 440.3 2.4 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KDO24835.1 - 2.8e-71 240.2 3.2 3.8e-71 239.7 3.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Sugar_tr PF00083.24 KDO24835.1 - 1.8e-33 116.1 11.8 1.8e-33 116.1 11.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO24835.1 - 3e-24 85.6 21.5 6e-24 84.6 21.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily NAGLU_N PF12971.7 KDO24835.1 - 2e-17 62.7 0.0 7e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain TRI12 PF06609.13 KDO24835.1 - 6.8e-05 21.5 5.6 0.00012 20.6 5.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KDO24835.1 - 0.0022 17.4 14.2 0.0041 16.5 14.2 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 KDO24835.1 - 0.029 13.3 8.9 0.0078 15.2 2.7 2.5 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KDO24835.1 - 0.072 11.9 3.7 2.2 7.0 0.2 2.3 2 0 0 2 2 2 0 MFS_1 like family Metallophos PF00149.28 KDO24836.1 - 3.7e-10 40.6 0.6 5.9e-10 40.0 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KDO24836.1 - 4.5e-08 33.6 0.2 2.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KDO24836.1 - 4.7e-08 33.8 0.4 1.2e-07 32.4 0.4 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 KDO24836.1 - 1.2e-05 25.5 0.0 0.00027 21.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M28 PF04389.17 KDO24837.1 - 9.2e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KDO24837.1 - 0.038 13.7 0.0 0.066 12.9 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 SID-1_RNA_chan PF13965.6 KDO24837.1 - 6.7 5.0 8.8 11 4.2 8.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Coa1 PF08695.10 KDO24838.1 - 6e-13 48.6 0.0 4.8e-10 39.2 0.0 2.7 2 1 0 2 2 2 2 Cytochrome oxidase complex assembly protein 1 MRP-S35 PF10246.9 KDO24838.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 DUF410 PF04190.13 KDO24839.1 - 1.7e-48 165.7 2.8 2.5e-48 165.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) VasI PF11319.8 KDO24839.1 - 0.02 14.6 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Vps54_N PF10475.9 KDO24839.1 - 0.027 13.8 0.1 1.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex GPP34 PF05719.11 KDO24839.1 - 0.033 14.2 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) FlbT PF07378.11 KDO24839.1 - 0.44 10.6 2.2 3.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Flagellar protein FlbT Dynamin_M PF01031.20 KDO24840.1 - 3.9e-31 108.3 0.0 1.3e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KDO24840.1 - 2.1e-30 106.0 0.0 3.6e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KDO24840.1 - 0.00081 19.5 0.0 0.0043 17.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4088 PF13317.6 KDO24840.1 - 0.038 13.6 0.8 0.25 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) GED PF02212.18 KDO24840.1 - 0.45 10.7 2.4 4.4 7.5 0.0 2.8 2 1 1 3 3 3 0 Dynamin GTPase effector domain Got1 PF04178.12 KDO24841.1 - 2e-17 63.6 13.9 2.6e-17 63.3 13.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2157 PF09925.9 KDO24841.1 - 0.25 11.1 7.6 0.36 10.6 7.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF308 PF03729.13 KDO24841.1 - 0.28 11.6 16.4 0.075 13.4 9.7 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) MDM10 PF12519.8 KDO24841.1 - 0.28 10.0 0.0 0.28 10.0 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4418 PF14387.6 KDO24841.1 - 0.44 10.8 5.2 0.37 11.0 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) DUF373 PF04123.13 KDO24841.1 - 4.4 6.7 5.7 5.1 6.4 5.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PAF-AH_p_II PF03403.13 KDO24842.1 - 4.7e-45 153.7 0.0 1.6e-44 152.0 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KDO24842.1 - 3e-10 40.2 0.0 4.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KDO24842.1 - 1.3e-09 37.3 0.1 2.9e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KDO24842.1 - 5.4e-07 29.1 0.4 0.0076 15.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO24842.1 - 1.5e-06 29.0 0.5 2.9e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KDO24842.1 - 7.5e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KDO24842.1 - 0.00024 20.9 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KDO24842.1 - 0.00041 19.5 0.1 0.028 13.4 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase PGAP1 PF07819.13 KDO24842.1 - 0.004 16.9 0.2 0.0078 16.0 0.2 1.5 1 1 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 KDO24842.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KDO24842.1 - 0.058 12.9 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KDO24842.1 - 0.072 12.7 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Tmemb_14 PF03647.13 KDO24843.1 - 4.3e-06 27.4 1.0 5.7e-06 27.0 1.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1772 PF08592.11 KDO24843.1 - 0.003 17.9 0.8 0.0047 17.2 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Tmemb_14 PF03647.13 KDO24844.1 - 7.4e-23 81.1 10.3 8.8e-23 80.9 10.3 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Chromate_transp PF02417.15 KDO24844.1 - 0.023 14.8 1.8 0.027 14.6 1.8 1.1 1 0 0 1 1 1 0 Chromate transporter SLATT_1 PF18181.1 KDO24844.1 - 0.03 14.2 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Glug PF07581.12 KDO24844.1 - 1.8 9.2 7.8 0.5 10.9 4.3 1.9 2 0 0 2 2 2 0 The GLUG motif tRNA-synt_His PF13393.6 KDO24845.1 - 0.2 10.9 2.2 0.14 11.4 0.2 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase WD40 PF00400.32 KDO24846.1 - 5.2e-11 42.9 9.9 0.11 13.4 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO24846.1 - 2.6e-06 27.6 0.8 0.0026 18.0 0.1 3.5 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO24846.1 - 0.00069 18.4 1.5 0.018 13.7 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Complex1_LYR PF05347.15 KDO24847.1 - 2e-12 46.9 0.2 3e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO24847.1 - 0.001 19.7 0.1 0.0012 19.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KDO24847.1 - 0.0045 17.6 0.1 0.0052 17.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Disintegrin PF00200.23 KDO24848.1 - 1.7e-20 73.6 93.1 1.5e-05 25.6 14.2 7.6 5 3 0 5 5 5 5 Disintegrin Disintegrin PF00200.23 KDO24849.1 - 5.6e-10 39.9 57.1 2.3e-05 25.1 10.4 4.4 3 2 0 3 3 3 3 Disintegrin AMP-binding PF00501.28 KDO24850.1 - 1.3e-53 182.1 0.1 1.6e-53 181.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO24850.1 - 8.4e-19 68.3 0.0 1.8e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAD PF02109.16 KDO24851.1 - 1.5e-43 147.6 2.6 1.6e-43 147.4 2.6 1.0 1 0 0 1 1 1 1 DAD family E1-E2_ATPase PF00122.20 KDO24851.1 - 0.036 13.6 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase MNHE PF01899.16 KDO24851.1 - 0.063 13.0 0.4 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF765 PF05570.11 KDO24851.1 - 2.9 8.1 9.1 4.3 7.6 4.9 2.5 2 1 0 2 2 2 0 Circovirus protein of unknown function (DUF765) HECT PF00632.25 KDO24852.1 - 8e-65 219.3 0.0 9.9e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO24852.1 - 0.015 14.6 1.4 0.026 13.8 1.4 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KDO24852.1 - 0.15 11.5 0.4 0.3 10.5 0.4 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Uricase PF01014.18 KDO24853.1 - 4.1e-54 182.4 0.0 2.4e-27 95.7 0.6 2.1 2 0 0 2 2 2 2 Uricase HSF_DNA-bind PF00447.17 KDO24854.1 - 1.4e-21 76.9 0.0 1.7e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding GDI PF00996.18 KDO24855.1 - 3.1e-47 161.1 0.0 1.2e-46 159.2 0.0 1.7 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KDO24855.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Voldacs PF03517.13 KDO24855.1 - 0.094 12.8 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling ThylakoidFormat PF11264.8 KDO24855.1 - 0.17 11.5 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 Thylakoid formation protein Ank_2 PF12796.7 KDO24856.1 - 2.5e-16 60.0 4.5 3.5e-05 24.3 0.0 5.6 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24856.1 - 1.3e-10 41.5 8.9 0.035 14.7 0.0 6.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24856.1 - 6e-07 29.6 8.8 0.38 11.1 0.0 7.4 6 3 3 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24856.1 - 1.7e-06 27.9 5.1 8.2 7.4 0.0 8.2 10 0 0 10 10 10 1 Ankyrin repeat HECT PF00632.25 KDO24857.1 - 9.2e-66 222.4 0.0 1.1e-65 222.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps36-NZF-N PF16988.5 KDO24857.1 - 0.11 11.9 0.3 0.24 10.8 0.3 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KDO24857.1 - 0.28 10.5 1.0 0.49 9.7 1.0 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DAD PF02109.16 KDO24858.1 - 1.5e-43 147.6 2.6 1.6e-43 147.4 2.6 1.0 1 0 0 1 1 1 1 DAD family E1-E2_ATPase PF00122.20 KDO24858.1 - 0.053 13.0 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase MNHE PF01899.16 KDO24858.1 - 0.063 13.0 0.4 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF765 PF05570.11 KDO24858.1 - 1.2 9.4 7.7 1.9 8.8 3.6 2.5 2 1 0 2 2 2 0 Circovirus protein of unknown function (DUF765) AMP-binding PF00501.28 KDO24859.1 - 4.1e-63 213.4 0.1 5.2e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO24859.1 - 1.1e-18 67.9 0.0 3.2e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AA_permease_2 PF13520.6 KDO24861.1 - 2.6e-33 115.5 44.1 3.7e-33 115.0 44.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO24861.1 - 2.8e-29 102.1 41.4 3.5e-29 101.7 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease AC_N PF16214.5 KDO24861.1 - 0.85 8.7 5.0 1.6 7.8 5.0 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Ank_2 PF12796.7 KDO24862.1 - 1.7e-19 70.2 5.0 5.6e-09 36.5 0.2 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24862.1 - 2.7e-15 56.5 7.3 2.7e-06 27.8 0.1 5.9 4 3 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO24862.1 - 1.8e-12 47.2 11.8 0.0027 18.0 0.1 6.8 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24862.1 - 6.7e-10 38.4 5.7 5 8.0 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 KDO24862.1 - 0.0011 19.3 7.1 38 5.0 0.1 6.3 3 2 0 3 3 3 0 Ankyrin repeat HA PF03457.14 KDO24862.1 - 0.012 16.0 1.6 24 5.4 0.0 4.3 4 1 1 5 5 5 0 Helicase associated domain DUF5049 PF16468.5 KDO24862.1 - 0.031 14.2 0.1 5.5 7.0 0.0 4.0 5 1 0 5 5 5 0 Domain of unknown function (DUF5049) OMPdecase PF00215.24 KDO24863.1 - 7.3e-29 101.0 0.1 1.5e-28 100.0 0.0 1.5 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KDO24863.1 - 1.5e-20 73.4 0.1 3.1e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Phage_Coat_Gp8 PF05371.12 KDO24863.1 - 0.09 12.6 2.6 0.35 10.7 2.6 2.0 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Toprim_3 PF13362.6 KDO24863.1 - 0.27 11.6 1.9 1.2 9.6 0.1 2.6 2 1 1 3 3 3 0 Toprim domain Pyr_redox_2 PF07992.14 KDO24866.1 - 3.1e-07 29.9 0.0 3.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KDO24866.1 - 3e-06 26.3 0.1 3.5e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KDO24866.1 - 9e-05 22.5 0.0 0.00029 20.8 0.1 1.7 1 1 1 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KDO24866.1 - 9.6e-05 22.9 0.1 0.00016 22.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO24866.1 - 0.00016 21.4 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KDO24866.1 - 0.0008 18.8 0.2 0.00097 18.5 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO24866.1 - 0.00092 19.4 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KDO24866.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KDO24866.1 - 0.002 17.4 0.1 0.0024 17.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KDO24866.1 - 0.0038 16.3 0.1 0.0051 15.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KDO24866.1 - 0.0041 15.9 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KDO24866.1 - 0.005 16.0 0.5 0.23 10.5 0.9 2.0 1 1 1 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KDO24866.1 - 0.021 14.1 0.2 0.026 13.8 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KDO24866.1 - 0.079 13.4 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KDO24866.1 - 0.098 11.7 0.4 0.12 11.5 0.4 1.1 1 0 0 1 1 1 0 FAD binding domain PHB_acc PF05233.13 KDO24867.1 - 0.15 12.1 0.1 27 4.9 0.0 2.5 2 0 0 2 2 2 0 PHB accumulation regulatory domain Pyr_redox_2 PF07992.14 KDO24868.1 - 1.3e-37 129.7 2.3 1.5e-37 129.5 2.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO24868.1 - 7.1e-15 55.3 1.1 1.9e-07 31.5 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO24868.1 - 9.6e-08 31.5 2.9 0.017 14.2 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KDO24868.1 - 3.3e-07 29.9 0.1 0.00044 19.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO24868.1 - 1.5e-06 28.0 9.0 0.0012 18.5 0.2 3.2 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KDO24868.1 - 1.8e-05 24.8 0.8 0.49 10.4 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KDO24868.1 - 5.7e-05 22.4 0.1 0.012 14.8 0.1 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KDO24868.1 - 5.8e-05 23.3 1.7 0.0057 16.9 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KDO24868.1 - 0.00021 20.7 0.0 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.6 KDO24868.1 - 0.0003 21.2 0.3 0.34 11.4 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.14 KDO24868.1 - 0.00039 19.4 2.5 0.0023 16.9 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 KDO24868.1 - 0.00076 19.7 0.3 0.69 10.2 0.1 2.4 2 0 0 2 2 2 2 TrkA-N domain HI0933_like PF03486.14 KDO24868.1 - 0.0012 17.7 1.1 0.23 10.1 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KDO24868.1 - 0.0014 17.9 1.1 0.072 12.3 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KDO24868.1 - 0.0022 17.3 1.8 0.12 11.6 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 KDO24868.1 - 0.019 14.1 2.0 0.067 12.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KDO24868.1 - 0.089 12.4 0.7 9.1 5.8 0.1 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KDO24868.1 - 0.28 10.2 7.7 4.1 6.4 0.8 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KDO24869.1 - 5.7e-29 101.3 0.5 6.9e-29 101.0 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO24869.1 - 7.5e-14 52.0 1.1 4.1e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO24869.1 - 4.1e-10 39.4 0.3 6.2e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO24869.1 - 1.6e-07 31.3 11.0 0.0011 18.7 0.5 3.9 2 2 2 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO24869.1 - 4.3e-07 29.3 1.3 0.033 13.2 0.2 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.6 KDO24869.1 - 5.8e-07 29.0 0.5 2.2e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KDO24869.1 - 6.4e-06 26.2 2.5 0.041 13.9 0.1 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KDO24869.1 - 8.8e-05 22.7 1.0 0.23 11.7 0.1 2.6 2 0 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.14 KDO24869.1 - 0.00012 21.1 3.4 0.00073 18.5 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase ThiF PF00899.21 KDO24869.1 - 0.00019 20.9 1.2 0.0023 17.3 0.0 2.9 3 1 0 3 3 3 1 ThiF family NAD_binding_8 PF13450.6 KDO24869.1 - 0.00034 20.8 1.1 0.11 12.8 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KDO24869.1 - 0.00054 20.4 0.5 1.2 9.7 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 KDO24869.1 - 0.0045 15.7 2.2 2.4 6.8 0.2 3.2 3 1 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 KDO24869.1 - 0.0064 15.8 1.0 1.1 8.4 0.1 2.4 2 0 0 2 2 2 2 Thi4 family ApbA PF02558.16 KDO24869.1 - 0.075 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KDO24869.1 - 0.14 12.5 1.3 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KDO24869.1 - 0.2 11.2 0.7 17 4.9 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KDO24869.1 - 0.21 10.8 4.9 2.3 7.3 0.1 2.5 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 KDO24869.1 - 0.5 9.4 4.8 6.6 5.7 0.5 2.7 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 KDO24869.1 - 2 7.4 10.7 3.9 6.5 0.4 3.3 2 2 2 4 4 4 0 Glucose inhibited division protein A PDEase_I PF00233.19 KDO24871.1 - 3.3e-67 226.7 4.4 3.3e-67 226.7 4.4 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KDO24871.1 - 5.1e-30 104.8 0.5 1.1e-13 51.9 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 KDO24871.1 - 7.3e-12 45.8 0.0 1.3e-06 28.8 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KDO24871.1 - 0.00011 22.6 0.0 0.00089 19.6 0.0 2.4 2 1 0 2 2 2 1 GAF domain CCDC23 PF15674.5 KDO24871.1 - 0.065 13.3 0.1 0.28 11.2 0.1 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 Csm1_N PF18504.1 KDO24871.1 - 0.19 12.1 8.3 0.51 10.7 3.8 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain Ysc84 PF04366.12 KDO24872.1 - 5.1e-40 136.2 0.1 7.9e-40 135.6 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 KDO24872.1 - 2.2e-17 63.0 3.4 3.8e-17 62.2 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger GATA PF00320.27 KDO24872.1 - 0.024 14.2 0.5 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-ribbon_3 PF13248.6 KDO24872.1 - 0.074 12.5 0.9 9.5 5.8 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.6 KDO24872.1 - 5.7 7.0 9.0 13 5.9 8.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain DUF1325 PF07039.11 KDO24874.1 - 5.1e-10 39.5 0.0 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TetR_C_24 PF17932.1 KDO24874.1 - 0.03 14.6 0.3 0.053 13.8 0.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4819 PF16090.5 KDO24874.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) GDA1_CD39 PF01150.17 KDO24875.1 - 1.2e-44 152.7 0.0 1.7e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CitMHS PF03600.16 KDO24875.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter TM_PBP2_N PF16296.5 KDO24875.1 - 0.38 10.9 2.5 7.4 6.8 0.0 2.7 2 1 1 3 3 3 0 N-terminal of TM subunit in PBP-dependent ABC transporters DUF269 PF03270.13 KDO24876.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF269 SR-25 PF10500.9 KDO24876.1 - 0.23 11.0 10.4 0.5 9.9 10.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AA_permease_2 PF13520.6 KDO24877.1 - 1.1e-46 159.5 46.4 1.4e-46 159.2 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO24878.1 - 3.2e-47 161.3 46.9 4.4e-47 160.9 46.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO24879.1 - 4.7e-45 154.2 45.4 6.3e-45 153.8 45.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO24881.1 - 1.5e-44 152.5 42.3 2e-44 152.1 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3483 PF11982.8 KDO24881.1 - 3.1 7.4 8.4 4 7.0 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) DUF1129 PF06570.11 KDO24881.1 - 6 6.3 12.9 0.43 10.0 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) AA_permease_2 PF13520.6 KDO24882.1 - 1.3e-50 172.5 41.3 1.8e-50 172.1 41.3 1.2 1 0 0 1 1 1 1 Amino acid permease Rotamase_2 PF13145.6 KDO24883.1 - 0.0081 17.0 0.3 0.011 16.6 0.3 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain TTL PF03133.15 KDO24884.1 - 4e-83 278.9 0.0 6e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO24884.1 - 1.1e-05 24.8 0.0 0.00074 18.8 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO24884.1 - 0.0086 15.4 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp CENP-B_dimeris PF09026.10 KDO24884.1 - 0.046 14.1 4.9 0.19 12.1 4.9 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Roughex PF06020.11 KDO24884.1 - 2.3 7.2 6.0 3.4 6.7 6.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein LtrA PF06772.11 KDO24885.1 - 2.1e-25 89.7 21.9 2.8e-25 89.3 21.9 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4079 PF13301.6 KDO24885.1 - 0.74 10.0 7.2 0.092 12.9 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) MCCD1 PF15707.5 KDO24886.1 - 0.022 15.2 1.5 0.05 14.1 1.5 1.6 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 PreAtp-grasp PF18604.1 KDO24886.1 - 0.1 12.3 0.2 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Pre ATP-grasp domain Caldesmon PF02029.15 KDO24886.1 - 1.7 7.4 4.9 2.2 6.9 4.9 1.1 1 0 0 1 1 1 0 Caldesmon Csm1_N PF18504.1 KDO24886.1 - 2.1 8.7 5.2 1 9.8 0.9 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Phage_HK97_TLTM PF06120.11 KDO24887.1 - 0.0036 16.6 0.5 0.0053 16.0 0.5 1.2 1 0 0 1 1 1 1 Tail length tape measure protein AAA_13 PF13166.6 KDO24887.1 - 0.22 10.1 2.2 1.1 7.8 1.2 1.9 1 1 1 2 2 2 0 AAA domain SPO11_like PF03533.14 KDO24888.1 - 0.14 12.3 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 SPO11 homologue Harakiri PF15196.6 KDO24889.1 - 0.16 12.5 2.5 1.7 9.1 1.1 2.4 2 0 0 2 2 2 0 Activator of apoptosis harakiri ADIP PF11559.8 KDO24892.1 - 0.48 10.5 5.3 1 9.4 5.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Takusan PF04822.13 KDO24895.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.1 3 0 0 3 3 3 0 Takusan KLRAQ PF10205.9 KDO24895.1 - 0.043 14.0 3.2 0.36 11.1 1.9 2.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein GP57 PF17594.2 KDO24895.1 - 0.049 13.4 0.7 0.11 12.2 0.7 1.6 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 FadA PF09403.10 KDO24895.1 - 0.15 12.6 2.6 0.34 11.4 2.6 1.6 1 0 0 1 1 1 0 Adhesion protein FadA Fib_alpha PF08702.10 KDO24895.1 - 0.4 10.9 2.7 0.93 9.7 2.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF963 PF06131.11 KDO24896.1 - 0.97 8.9 2.9 0.73 9.3 0.8 1.8 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF1778 PF08681.11 KDO24897.1 - 0.0072 16.2 2.9 0.021 14.8 2.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) Peripla_BP_4 PF13407.6 KDO24897.1 - 0.045 13.3 0.7 0.065 12.8 0.7 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain DMPK_coil PF08826.10 KDO24897.1 - 0.048 13.8 0.3 0.048 13.8 0.3 2.2 3 0 0 3 3 3 0 DMPK coiled coil domain like LegC3_N PF18654.1 KDO24898.1 - 0.02 14.2 0.9 0.029 13.6 0.9 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain PRKG1_interact PF15898.5 KDO24898.1 - 0.026 15.4 2.9 0.056 14.3 2.9 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ASTN_2_hairpin PF18577.1 KDO24899.1 - 0.099 12.8 0.1 21 5.3 0.1 2.8 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain Vps5 PF09325.10 KDO24900.1 - 0.093 12.3 0.3 0.2 11.2 0.1 1.5 1 1 1 2 2 2 0 Vps5 C terminal like RseA_C PF03873.13 KDO24902.1 - 0.0062 16.7 1.1 0.014 15.6 1.1 1.6 1 0 0 1 1 1 1 Anti sigma-E protein RseA, C-terminal domain Vps5 PF09325.10 KDO24902.1 - 0.071 12.7 1.4 0.099 12.2 1.4 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Spc7 PF08317.11 KDO24903.1 - 0.008 15.1 4.1 0.012 14.5 4.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 KDO24903.1 - 0.019 14.3 5.1 0.031 13.6 5.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 KDO24903.1 - 0.025 13.5 5.8 0.045 12.6 5.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPD52 PF04201.15 KDO24903.1 - 0.026 14.1 1.6 0.049 13.3 1.6 1.4 1 0 0 1 1 1 0 Tumour protein D52 family APG6_N PF17675.1 KDO24903.1 - 0.031 14.8 10.1 0.06 13.9 10.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region KASH_CCD PF14662.6 KDO24903.1 - 0.046 13.5 4.3 0.075 12.9 4.3 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 KDO24903.1 - 0.047 13.9 5.3 0.089 13.0 5.3 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Tup_N PF08581.10 KDO24903.1 - 0.048 14.0 0.7 13 6.2 0.2 2.4 2 0 0 2 2 2 0 Tup N-terminal OmpH PF03938.14 KDO24903.1 - 0.061 13.7 5.1 0.069 13.5 0.8 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) JIP_LZII PF16471.5 KDO24903.1 - 0.13 12.5 0.6 0.27 11.4 0.6 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF2796 PF10986.8 KDO24903.1 - 0.13 12.2 5.7 0.23 11.4 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF4472 PF14739.6 KDO24903.1 - 0.15 12.8 5.1 0.42 11.4 4.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Rab5-bind PF09311.11 KDO24903.1 - 0.37 10.1 3.8 0.76 9.1 3.8 1.5 1 1 0 1 1 1 0 Rabaptin-like protein Ax_dynein_light PF10211.9 KDO24903.1 - 0.42 10.5 3.9 0.24 11.3 1.9 1.7 2 0 0 2 2 1 0 Axonemal dynein light chain SlyX PF04102.12 KDO24903.1 - 0.59 10.8 3.2 9.3 7.0 0.0 2.9 1 1 2 3 3 3 0 SlyX HAUS-augmin3 PF14932.6 KDO24903.1 - 0.93 9.0 6.4 1.5 8.3 6.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.8 KDO24903.1 - 1 9.4 4.9 1.8 8.6 4.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KDO24903.1 - 1.2 9.0 4.6 0.22 11.3 0.8 1.8 2 0 0 2 2 1 0 Septum formation initiator FUSC PF04632.12 KDO24903.1 - 1.3 7.5 10.2 1.9 6.9 10.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc24 PF08286.11 KDO24903.1 - 4.6 7.5 4.7 6.7 7.0 2.8 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 KDO24903.1 - 5.1 7.6 7.5 0.9 10.0 3.2 2.1 2 1 0 2 2 1 0 Cell division protein ZapB Peptidase_C48 PF02902.19 KDO24904.1 - 3.3e-05 23.8 0.0 5.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cnn_1N PF07989.11 KDO24904.1 - 0.19 11.9 1.1 0.41 10.8 1.1 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 KDO24904.1 - 2.7 8.3 4.9 6.4 7.1 4.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) M PF02370.16 KDO24904.1 - 9.9 7.1 6.7 7 7.6 2.1 2.8 2 0 0 2 2 2 0 M protein repeat Vps5 PF09325.10 KDO24905.1 - 0.054 13.0 0.2 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Vps5 C terminal like WXG100 PF06013.12 KDO24905.1 - 0.061 13.6 2.8 0.11 12.7 2.8 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Pkinase PF00069.25 KDO24906.1 - 6.5e-16 58.5 0.0 2.8e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KDO24906.1 - 1.2e-06 28.1 0.2 2.3e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KDO24906.1 - 0.0088 15.4 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_18 PF00704.28 KDO24907.1 - 3.8e-81 273.2 4.8 4.7e-81 272.9 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PT PF04886.12 KDO24907.1 - 7.3e-13 47.8 41.3 1.9e-08 33.7 18.7 3.5 2 1 1 3 3 3 2 PT repeat Glycoprotein_G PF00802.19 KDO24907.1 - 0.045 13.1 22.4 0.086 12.2 22.4 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Glyco_hydro_18 PF00704.28 KDO24908.1 - 1.1e-73 248.7 1.6 1.3e-73 248.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KDO24909.1 - 4.3e-80 269.8 4.4 5.3e-80 269.5 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PT PF04886.12 KDO24909.1 - 2.1e-12 46.4 45.1 1.5e-07 30.8 16.9 3.2 1 1 2 3 3 3 2 PT repeat MFS_2 PF13347.6 KDO24910.1 - 2.6e-12 46.0 7.3 2.6e-12 46.0 7.3 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein PKD_channel PF08016.12 KDO24911.1 - 3.1e-17 62.4 13.5 3.6e-11 42.4 10.3 2.5 2 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 KDO24911.1 - 3.9e-05 23.0 17.5 0.00023 20.5 17.2 2.1 1 1 1 2 2 2 1 Ion transport protein HTH_23 PF13384.6 KDO24911.1 - 0.058 13.2 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Lipase_3 PF01764.25 KDO24912.1 - 2.4e-28 98.8 0.0 3.8e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO24912.1 - 0.0041 17.8 0.0 0.0041 17.8 0.0 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KDO24912.1 - 0.0055 16.3 0.1 0.027 14.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KDO24912.1 - 0.099 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ammonium_transp PF00909.21 KDO24914.1 - 3.4e-86 289.4 26.1 6e-86 288.6 26.1 1.3 1 1 0 1 1 1 1 Ammonium Transporter Family Kazal_2 PF07648.15 KDO24915.1 - 1.4e-09 37.9 0.6 1.4e-09 37.9 0.6 4.0 3 2 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO24915.1 - 5.2e-07 29.6 2.2 5.2e-07 29.6 2.2 3.6 2 1 1 3 3 3 1 Kazal-type serine protease inhibitor domain Tom22 PF04281.13 KDO24915.1 - 0.039 13.7 0.4 0.06 13.1 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Ammonium_transp PF00909.21 KDO24916.1 - 2.4e-94 316.3 31.2 3e-94 316.0 31.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 KDO24917.1 - 2.7e-92 309.5 33.1 3.4e-92 309.2 33.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PKD_channel PF08016.12 KDO24918.1 - 2.1e-21 76.1 15.1 2e-17 63.0 8.6 3.1 2 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 KDO24918.1 - 7.9e-07 28.6 17.2 2.4e-06 27.0 17.2 1.8 1 1 0 1 1 1 1 Ion transport protein Kazal_2 PF07648.15 KDO24919.1 - 6.4e-10 39.0 27.1 7.1e-09 35.7 1.3 3.9 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO24919.1 - 0.0023 17.9 6.4 0.0023 17.9 6.4 3.9 1 1 2 3 3 3 1 Kazal-type serine protease inhibitor domain PKD_channel PF08016.12 KDO24920.1 - 2.6e-18 65.9 16.5 1.7e-13 50.1 11.8 3.3 3 0 0 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 KDO24920.1 - 6.4e-08 32.1 14.4 6.4e-08 32.1 14.4 1.7 2 0 0 2 2 2 1 Ion transport protein HATPase_c_4 PF13749.6 KDO24920.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal Ank_2 PF12796.7 KDO24921.1 - 8.5e-73 241.0 15.8 2.7e-17 63.1 1.2 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO24921.1 - 3e-61 203.1 13.1 1.4e-13 51.1 0.0 6.8 3 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO24921.1 - 4e-49 163.0 27.6 4.4e-07 30.1 0.3 9.6 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KDO24921.1 - 6.8e-43 144.2 18.3 1e-08 35.2 0.1 7.4 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO24921.1 - 2.1e-42 138.2 11.4 4.9e-05 23.4 0.0 9.4 10 0 0 10 10 10 8 Ankyrin repeat Peptidase_M48 PF01435.18 KDO24922.1 - 4.8e-36 124.4 0.0 8.6e-36 123.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 LRR_8 PF13855.6 KDO24923.1 - 1.3e-05 24.8 0.8 0.0017 18.1 4.1 2.6 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KDO24923.1 - 0.00029 21.2 0.6 0.00029 21.2 0.6 2.2 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) Phage_holin_3_6 PF07332.11 KDO24923.1 - 0.08 13.0 7.3 0.6 10.2 2.3 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_hydro_17 PF00332.18 KDO24924.1 - 0.00035 20.3 2.3 0.00074 19.2 2.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.18 KDO24925.1 - 3.9e-05 23.4 1.1 0.0022 17.6 1.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Bindin PF02084.15 KDO24925.1 - 0.19 11.9 0.1 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Bindin CDK2AP PF09806.9 KDO24925.1 - 0.95 9.5 5.6 2.1 8.4 5.6 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Shisa PF13908.6 KDO24926.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.7 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator zf_CCCH_5 PF18384.1 KDO24928.1 - 1.4 9.1 22.7 2.4 8.3 0.9 4.2 4 0 0 4 4 4 0 Unkempt Zinc finger domain 1 (Znf1) Transp_Tc5_C PF04236.15 KDO24928.1 - 2 8.8 17.0 0.57 10.6 1.4 3.9 1 1 2 3 3 3 0 Tc5 transposase C-terminal domain Rhomboid PF01694.22 KDO24929.1 - 7.9e-39 133.0 18.5 2.3e-38 131.6 16.4 2.1 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 KDO24929.1 - 0.00071 19.6 0.5 0.0017 18.3 0.2 1.5 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 KDO24929.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.3 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) DinB_2 PF12867.7 KDO24931.1 - 0.09 13.3 1.1 1.8 9.1 1.1 2.2 1 1 0 1 1 1 0 DinB superfamily Metalloenzyme PF01676.18 KDO24931.1 - 0.19 11.1 0.1 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily Ribosomal_L29e PF01779.17 KDO24933.1 - 5.9e-20 71.3 10.7 5.9e-20 71.3 10.7 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family TAFII55_N PF04658.13 KDO24933.1 - 0.38 10.5 5.4 0.39 10.4 5.4 1.0 1 0 0 1 1 1 0 TAFII55 protein conserved region Rrp15p PF07890.12 KDO24934.1 - 5.1e-21 75.4 6.0 5.1e-21 75.4 6.0 2.8 3 0 0 3 3 3 1 Rrp15p YL1 PF05764.13 KDO24934.1 - 0.96 9.5 32.9 0.048 13.8 14.0 2.2 1 1 1 2 2 2 0 YL1 nuclear protein START PF01852.19 KDO24935.1 - 8.8e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO24935.1 - 0.00063 19.8 4.1 0.0013 18.9 4.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Acyl_transf_3 PF01757.22 KDO24937.1 - 2.2e-20 73.0 42.9 2.2e-20 73.0 42.9 1.7 1 1 1 2 2 2 1 Acyltransferase family Vac14_Fig4_bd PF11916.8 KDO24938.1 - 3.1e-72 242.0 11.5 3.1e-72 242.0 11.5 2.6 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KDO24938.1 - 9e-48 160.8 0.1 2.4e-41 140.2 0.0 4.5 2 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KDO24938.1 - 1.9e-13 49.4 5.9 5.7e-05 23.0 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 KDO24938.1 - 9.7e-10 38.7 1.6 0.0012 19.0 0.0 4.4 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO24938.1 - 5.1e-08 33.3 0.1 0.18 12.4 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat CLASP_N PF12348.8 KDO24938.1 - 1.1e-06 28.4 0.0 0.0061 16.2 0.0 3.9 2 2 1 4 4 4 1 CLASP N terminal HEAT_2 PF13646.6 KDO24938.1 - 4.1e-06 27.1 0.5 2.5 8.5 0.0 5.5 4 3 1 5 5 5 2 HEAT repeats Tti2 PF10521.9 KDO24938.1 - 1.8e-05 24.5 3.0 0.0067 16.0 0.0 3.7 3 1 1 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 KDO24938.1 - 0.03 14.5 2.6 1.1 9.5 0.7 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KDO24938.1 - 0.082 13.2 0.6 1.8 8.9 0.0 3.4 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain TIP120 PF08623.10 KDO24938.1 - 0.091 12.5 4.3 1.9 8.2 0.4 3.3 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) RasGEF_N_2 PF14663.6 KDO24938.1 - 0.11 12.9 2.6 4.1 7.8 0.0 3.8 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arf PF00025.21 KDO24940.1 - 3.4e-66 222.0 0.1 3.9e-66 221.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO24940.1 - 2.9e-14 53.0 0.3 1.2e-09 37.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KDO24940.1 - 7.1e-13 48.8 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO24940.1 - 2.9e-12 46.4 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KDO24940.1 - 5.2e-10 39.1 0.0 6.2e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KDO24940.1 - 5.5e-10 39.0 0.0 6.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO24940.1 - 3.9e-07 30.1 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO24940.1 - 0.014 15.9 0.1 0.025 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KDO24940.1 - 0.024 14.2 0.0 0.25 10.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KDO24940.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KDO24940.1 - 0.079 12.5 0.0 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO24940.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.2 2 1 0 2 2 2 0 NACHT domain ATP-grasp_2 PF08442.10 KDO24941.1 - 1.9e-65 220.2 1.5 5.5e-65 218.7 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KDO24941.1 - 1e-24 87.1 0.8 1.7e-24 86.4 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KDO24941.1 - 7.5e-08 32.1 0.5 1.9e-07 30.8 0.1 1.9 2 1 0 2 2 2 1 ATP-grasp domain Peripla_BP_4 PF13407.6 KDO24941.1 - 0.0024 17.5 0.7 0.0042 16.7 0.7 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain Succ_CoA_lig PF13607.6 KDO24941.1 - 0.031 14.1 0.3 0.057 13.2 0.3 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Toprim_2 PF13155.6 KDO24941.1 - 0.036 14.5 0.1 0.45 11.0 0.1 2.5 2 0 0 2 2 2 0 Toprim-like GARS_A PF01071.19 KDO24941.1 - 0.038 13.8 3.6 2.6 7.8 0.3 2.8 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TPR_2 PF07719.17 KDO24942.1 - 9.9e-10 37.8 1.3 0.00028 20.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO24942.1 - 2.4e-08 33.5 1.9 0.0012 18.5 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO24942.1 - 1.2e-07 31.3 1.4 9.7e-07 28.4 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KDO24942.1 - 2.7e-07 30.9 9.9 0.00077 20.1 0.6 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO24942.1 - 6.1e-07 29.5 2.9 8.3e-07 29.1 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO24942.1 - 8.6e-07 29.4 0.6 8.6e-07 29.4 0.6 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO24942.1 - 1e-06 28.7 0.7 0.00017 21.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO24942.1 - 6.7e-06 26.6 1.1 3.6e-05 24.3 0.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO24942.1 - 0.00041 20.3 0.7 0.18 12.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO24942.1 - 0.003 17.8 3.4 0.003 17.8 3.4 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO24942.1 - 0.0092 16.6 0.1 9.5 7.1 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO24942.1 - 0.018 14.9 2.6 5.3 7.1 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FAT PF02259.23 KDO24942.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 FAT domain Abhydrolase_2 PF02230.16 KDO24943.1 - 1.2e-21 77.6 0.0 1.7e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KDO24943.1 - 0.00037 19.8 0.5 3 7.1 0.1 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 KDO24943.1 - 0.0055 16.4 0.2 0.0098 15.6 0.2 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 KDO24943.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KDO24943.1 - 0.18 11.7 0.0 0.64 9.9 0.0 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf_C2HC_14 PF18574.1 KDO24944.1 - 0.00013 21.7 3.0 0.12 12.2 0.2 2.4 2 0 0 2 2 2 2 C2HC Zing finger domain zf-C2H2_12 PF18658.1 KDO24944.1 - 0.021 14.4 1.8 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger C2H2-type Gp37 PF09646.10 KDO24944.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Gp37 protein DM PF00751.18 KDO24944.1 - 2.7 7.9 11.1 2.8 7.9 2.5 3.2 3 0 0 3 3 3 0 DM DNA binding domain DUF1295 PF06966.12 KDO24945.1 - 0.0086 15.6 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KDO24945.1 - 0.012 14.5 0.6 0.018 13.8 0.6 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family UbiA PF01040.18 KDO24945.1 - 0.24 10.7 12.6 0.38 10.0 12.4 1.5 1 1 0 1 1 1 0 UbiA prenyltransferase family PEMT PF04191.13 KDO24945.1 - 0.49 10.8 4.0 0.5 10.8 1.7 2.1 1 1 1 2 2 2 0 Phospholipid methyltransferase WD40 PF00400.32 KDO24946.1 - 4.6e-08 33.6 9.2 0.11 13.4 0.0 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO24946.1 - 6.9e-06 25.2 0.1 0.047 12.7 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Noc2 PF03715.13 KDO24948.1 - 6.3e-79 265.3 7.5 6.6e-79 265.3 5.9 1.7 2 0 0 2 2 2 1 Noc2p family BUD22 PF09073.10 KDO24948.1 - 0.012 15.0 37.7 0.088 12.1 11.6 2.2 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KDO24948.1 - 0.012 13.8 0.5 0.012 13.8 0.5 3.1 2 1 1 3 3 3 0 Nop14-like family EF-hand_1 PF00036.32 KDO24949.1 - 4.5e-35 116.6 18.9 2.8e-09 35.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO24949.1 - 1.7e-30 105.2 11.4 2.9e-16 59.7 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO24949.1 - 3.9e-27 91.8 10.9 1.4e-09 37.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KDO24949.1 - 8.5e-26 89.6 15.3 3.3e-12 46.0 1.1 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO24949.1 - 2.5e-18 64.7 17.7 5e-06 25.8 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KDO24949.1 - 5.5e-15 55.4 0.4 2.9e-07 30.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KDO24949.1 - 1.5e-06 28.1 7.9 0.12 12.4 0.8 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KDO24949.1 - 9e-05 22.8 1.6 0.094 13.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KDO24949.1 - 0.00034 20.8 0.1 0.41 10.9 0.1 2.4 2 0 0 2 2 2 2 Dockerin type I domain SurA_N_3 PF13624.6 KDO24949.1 - 0.00038 20.3 2.3 0.22 11.3 0.2 2.2 1 1 1 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 KDO24949.1 - 0.00049 20.4 1.7 0.27 11.6 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 KDO24949.1 - 0.0096 15.8 2.9 1.4 8.8 0.3 2.7 1 1 1 2 2 2 2 SurA N-terminal domain DUF4601 PF15373.6 KDO24949.1 - 0.014 14.4 0.1 0.028 13.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) PMBR PF09373.10 KDO24949.1 - 0.016 15.3 1.1 45 4.4 0.0 4.7 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF853 PF05872.12 KDO24949.1 - 0.027 13.1 0.2 0.51 8.9 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.13 KDO24949.1 - 0.027 14.4 1.6 8 6.4 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein SUB1_ProdP9 PF18213.1 KDO24949.1 - 0.03 14.2 2.7 0.032 14.1 0.2 2.0 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 EF-hand_11 PF08976.11 KDO24949.1 - 0.073 13.9 0.4 13 6.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain LETM1 PF07766.13 KDO24949.1 - 0.092 12.1 3.0 0.13 11.6 1.4 2.0 1 1 0 1 1 1 0 LETM1-like protein DUF3008 PF11450.8 KDO24949.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.9 4 0 0 4 4 3 0 Protein of unknwon function (DUF3008) DUF21 PF01595.20 KDO24949.1 - 0.26 11.0 0.6 0.67 9.6 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Toprim_2 PF13155.6 KDO24949.1 - 0.37 11.2 2.4 9.5 6.7 0.1 2.5 1 1 0 2 2 2 0 Toprim-like Phg_2220_C PF09524.10 KDO24949.1 - 0.42 10.7 2.8 5.1 7.2 0.1 2.6 2 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Gp-FAR-1 PF05823.12 KDO24949.1 - 1.9 8.8 7.0 2 8.8 0.2 2.9 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HA PF03457.14 KDO24950.1 - 5.1e-23 81.2 5.2 9e-11 41.9 0.0 3.8 4 1 0 4 4 4 2 Helicase associated domain Biotin_carb_C PF02785.19 KDO24951.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Biotin_carb_C PF02785.19 KDO24955.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain CDT1 PF08839.11 KDO24956.1 - 4.4e-11 43.4 0.0 9.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 KDO24956.1 - 1.5e-05 25.3 4.9 2.5e-05 24.6 0.3 2.9 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain DUF2985 PF11204.8 KDO24957.1 - 1.8e-10 40.8 2.0 1.8e-10 40.8 2.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) LapA_dom PF06305.11 KDO24957.1 - 3.4 7.6 13.3 1.4 8.7 0.5 3.0 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 KDO24958.1 - 2e-38 132.0 0.2 1.1e-18 68.0 0.0 3.9 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KDO24958.1 - 1.2e-18 68.0 6.3 0.00058 19.8 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO24958.1 - 5.2e-13 48.9 1.5 1e-05 25.1 0.2 4.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KDO24958.1 - 1.2e-07 31.6 0.1 0.00051 19.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KDO24958.1 - 3.7e-07 30.5 0.7 0.0034 17.6 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KDO24958.1 - 8.4e-07 28.6 0.9 0.033 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO24958.1 - 5.9e-06 26.9 3.8 0.0035 17.9 0.2 3.2 3 1 0 3 3 3 2 AAA domain ABC_tran_Xtn PF12848.7 KDO24958.1 - 1.1e-05 25.4 4.4 3.7e-05 23.7 4.4 1.9 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 KDO24958.1 - 1.4e-05 25.4 1.4 0.0097 16.2 0.1 2.9 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KDO24958.1 - 2e-05 24.6 2.9 0.017 15.1 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 KDO24958.1 - 8.9e-05 22.4 2.1 0.15 11.7 0.0 3.6 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 KDO24958.1 - 0.00014 21.9 0.3 0.56 10.3 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO24958.1 - 0.00014 22.4 1.5 0.1 13.2 0.1 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KDO24958.1 - 0.00048 20.1 0.2 0.28 11.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KDO24958.1 - 0.00076 19.3 0.4 3 7.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 KDO24958.1 - 0.00095 18.2 0.8 0.91 8.4 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KDO24958.1 - 0.001 19.5 7.7 0.056 13.8 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KDO24958.1 - 0.0016 18.8 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 KDO24958.1 - 0.0016 18.0 0.1 0.073 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO24958.1 - 0.0019 17.4 0.6 0.86 8.7 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KDO24958.1 - 0.0037 17.4 0.1 2.2 8.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KDO24958.1 - 0.0037 17.2 0.8 1.2 9.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Roc PF08477.13 KDO24958.1 - 0.0064 16.7 0.1 6.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KDO24958.1 - 0.0073 15.8 5.0 0.92 9.0 0.0 3.1 2 1 1 3 3 3 1 P-loop containing dynein motor region SbcCD_C PF13558.6 KDO24958.1 - 0.0082 16.4 0.5 0.87 9.9 0.0 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 KDO24958.1 - 0.011 15.5 0.3 4.4 7.0 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 KDO24958.1 - 0.019 14.7 1.3 2.3 8.0 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KDO24958.1 - 0.03 14.7 0.7 14 6.1 0.0 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KDO24958.1 - 0.046 13.0 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2813 PF11398.8 KDO24958.1 - 0.057 12.7 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) FtsK_SpoIIIE PF01580.18 KDO24958.1 - 0.078 12.3 0.4 4.5 6.6 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 KDO24958.1 - 0.083 12.9 1.3 11 6.0 0.3 2.9 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KDO24958.1 - 0.096 12.7 0.1 31 4.6 0.1 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 KDO24958.1 - 0.1 11.7 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.21 KDO24958.1 - 0.11 11.9 0.6 1.4 8.4 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 KDO24958.1 - 0.13 12.2 1.5 2.6 7.9 0.0 2.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 KDO24958.1 - 0.3 10.6 3.9 25 4.4 1.7 3.5 3 1 0 3 3 2 0 AAA domain DUF4878 PF12870.7 KDO24958.1 - 1 9.7 4.8 6.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Dynamin_N PF00350.23 KDO24958.1 - 1.3 9.0 4.5 17 5.4 0.0 3.3 4 0 0 4 4 3 0 Dynamin family ABC_ATPase PF09818.9 KDO24958.1 - 2.9 6.6 6.2 0.4 9.4 0.4 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_13 PF13166.6 KDO24958.1 - 4.2 5.9 9.3 4.5 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain WLM PF08325.10 KDO24959.1 - 2.1e-36 125.8 0.0 4.2e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 WLM domain PUB PF09409.10 KDO24959.1 - 6.4e-11 42.0 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 KDO24959.1 - 2e-08 33.9 0.0 5.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF45 PF01863.17 KDO24959.1 - 0.0047 17.0 0.3 0.014 15.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 Spermine_synt_N PF17284.2 KDO24959.1 - 0.021 14.7 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain ARL2_Bind_BART PF11527.8 KDO24960.1 - 0.0081 16.2 0.1 0.0089 16.1 0.1 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART LPP PF04728.13 KDO24961.1 - 0.31 11.5 2.3 3.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper HR1 PF02185.16 KDO24961.1 - 0.46 10.6 4.4 2.4 8.3 0.3 3.3 3 1 0 3 3 3 0 Hr1 repeat Rhodanese PF00581.20 KDO24962.1 - 3.8e-26 91.7 0.0 2.2e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain POTRA_2 PF08479.11 KDO24962.1 - 0.12 12.2 0.0 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 POTRA domain, ShlB-type Pkinase PF00069.25 KDO24963.1 - 1.9e-62 211.0 0.0 2.5e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO24963.1 - 7e-35 120.6 0.0 9.9e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO24963.1 - 4e-11 42.8 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kinase-like PF14531.6 KDO24963.1 - 2.1e-07 30.6 0.0 6.3e-07 29.0 0.0 1.8 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 KDO24963.1 - 0.00028 20.6 0.1 0.24 11.0 0.0 2.9 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO24963.1 - 0.071 13.0 0.1 0.071 13.0 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family COPI_assoc PF08507.10 KDO24964.1 - 1.6e-13 50.8 8.7 2.2e-13 50.4 8.7 1.2 1 0 0 1 1 1 1 COPI associated protein Pox_P35 PF03213.14 KDO24964.1 - 0.032 13.5 2.4 0.048 12.9 2.4 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein S_4TM PF18159.1 KDO24964.1 - 0.097 12.0 2.7 0.15 11.3 2.7 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3784 PF12650.7 KDO24964.1 - 8.3 6.7 12.6 3.4 7.9 4.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) Peptidase_M24 PF00557.24 KDO24965.1 - 2.3e-17 63.4 0.3 7.1e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 zf-Mss51 PF13824.6 KDO24965.1 - 0.076 13.1 0.2 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 ThiF PF00899.21 KDO24966.1 - 9.8e-31 107.0 0.2 1.2e-30 106.7 0.2 1.1 1 0 0 1 1 1 1 ThiF family E1_FCCH PF16190.5 KDO24966.1 - 2.2e-21 75.8 0.1 3.9e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KDO24966.1 - 2.5e-19 69.2 0.0 4.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Myb_DNA-bind_4 PF13837.6 KDO24968.1 - 0.0014 19.0 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF572 PF04502.13 KDO24969.1 - 3.5 7.2 8.9 4.1 6.9 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Abhydrolase_4 PF08386.10 KDO24971.1 - 0.033 14.3 0.2 0.063 13.4 0.2 1.4 1 0 0 1 1 1 0 TAP-like protein Ter PF05472.11 KDO24975.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) OppC_N PF12911.7 KDO24975.1 - 6.7 6.8 6.8 1.7 8.7 2.3 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2617 PF10936.8 KDO24976.1 - 0.0044 17.1 0.3 0.0047 17.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF2617 DNase-RNase PF02577.14 KDO24976.1 - 0.031 13.9 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Bifunctional nuclease UBA_3 PF09288.10 KDO24977.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain LSM PF01423.22 KDO24980.1 - 7.2e-18 64.0 0.9 9.3e-18 63.7 0.9 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 KDO24980.1 - 0.0071 16.2 0.5 0.014 15.3 0.5 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SM-ATX PF14438.6 KDO24980.1 - 0.079 13.1 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain MRP-S23 PF10484.9 KDO24981.1 - 0.0025 18.1 0.5 0.029 14.6 0.5 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 FAM72 PF14976.6 KDO24985.1 - 0.025 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 FAM72 protein LRR_4 PF12799.7 KDO24987.1 - 0.071 13.6 0.0 42 4.7 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO24987.1 - 0.64 10.2 13.0 2.9 8.2 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat LRR_6 PF13516.6 KDO24989.1 - 0.1 12.7 0.9 15 6.0 0.0 4.6 6 0 0 6 6 6 0 Leucine Rich repeat LRR_6 PF13516.6 KDO24990.1 - 0.15 12.2 3.1 23 5.4 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S34 PF16053.5 KDO24991.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 MMR_HSR1 PF01926.23 KDO24993.1 - 0.00011 22.2 0.0 0.00038 20.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase MACPF PF01823.19 KDO24993.1 - 0.00018 21.7 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Dynamin_N PF00350.23 KDO24993.1 - 0.00062 19.9 0.1 0.0043 17.1 0.1 2.3 1 1 1 2 2 2 1 Dynamin family GBP PF02263.19 KDO24993.1 - 0.0014 17.9 0.0 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KDO24993.1 - 0.014 13.5 0.0 0.03 12.5 0.0 1.5 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) PX PF00787.24 KDO24995.1 - 4.3e-05 23.5 0.0 8.4e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 PX domain DUF1390 PF07150.11 KDO24995.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF3024 PF11225.8 KDO24995.1 - 0.19 12.0 0.0 0.86 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) adh_short_C2 PF13561.6 KDO24996.1 - 4.3e-55 186.8 3.5 5.3e-55 186.5 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO24996.1 - 1.7e-48 164.7 1.8 2e-48 164.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO24996.1 - 1.1e-13 51.5 4.0 1.2e-13 51.3 2.5 1.7 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 KDO24996.1 - 0.034 14.7 2.0 0.071 13.7 0.1 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KDO24996.1 - 0.035 13.6 0.5 0.33 10.4 0.1 2.2 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO24996.1 - 0.22 11.4 4.2 0.31 10.9 4.2 1.5 1 1 0 1 1 1 0 NAD(P)H-binding PIP5K PF01504.18 KDO24997.1 - 4.6e-69 232.7 0.5 1.5e-68 231.0 0.5 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 KDO24997.1 - 3.4e-07 29.8 0.2 3.4e-07 29.8 0.2 2.5 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) DoxX_2 PF13564.6 KDO24997.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 DoxX-like family Adeno_E3B PF03376.14 KDO24997.1 - 0.033 14.4 0.9 0.033 14.4 0.9 2.1 2 0 0 2 2 2 0 Adenovirus E3B protein AstA PF04958.12 KDO24997.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF5058 PF16481.5 KDO24997.1 - 0.4 10.3 3.0 16 5.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5058) FixH PF05751.11 KDO24997.1 - 7.8 6.5 7.7 1.2 9.2 1.6 2.4 2 0 0 2 2 2 0 FixH ADK PF00406.22 KDO24998.1 - 1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KDO24998.1 - 2e-33 115.7 0.0 2.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO24998.1 - 3.4e-06 27.6 0.0 4.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO24998.1 - 5.4e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KDO24998.1 - 0.0082 16.6 0.1 1.3 9.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KDO24998.1 - 0.026 14.9 0.4 0.059 13.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KDO24998.1 - 0.15 11.7 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Ploopntkinase3 PF18751.1 KDO24998.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Kelch_3 PF13415.6 KDO24999.1 - 1.5e-14 53.8 1.7 0.0019 18.4 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO24999.1 - 8.2e-10 38.5 0.0 0.36 10.9 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KDO24999.1 - 3e-09 36.7 0.1 0.005 16.8 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain PRIMA1 PF16101.5 KDO25001.1 - 0.00037 20.5 0.2 0.00037 20.5 0.2 2.1 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 Mid2 PF04478.12 KDO25001.1 - 0.0027 17.6 0.4 0.0054 16.6 0.4 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KDO25001.1 - 0.0075 16.2 1.3 0.0075 16.2 1.3 2.1 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 KDO25001.1 - 0.033 14.0 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) OAD_gamma PF04277.13 KDO25001.1 - 0.16 12.6 2.1 0.2 12.3 0.1 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Pox_D3 PF04580.13 KDO25002.1 - 0.089 12.4 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein BRX PF08381.11 KDO25002.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 LRR_6 PF13516.6 KDO25003.1 - 0.0015 18.4 5.8 0.0099 15.9 0.0 4.2 4 1 0 4 4 4 1 Leucine Rich repeat RVT_2 PF07727.14 KDO25003.1 - 0.0017 18.0 0.4 0.015 14.9 0.0 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1643 PF07799.12 KDO25003.1 - 0.17 12.0 0.2 0.42 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Mitofilin PF09731.9 KDO25004.1 - 0.00058 18.8 15.5 0.00084 18.3 15.5 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Macoilin PF09726.9 KDO25004.1 - 0.0017 17.1 13.2 0.0025 16.5 13.2 1.4 1 0 0 1 1 1 1 Macoilin family CLN3 PF02487.17 KDO25004.1 - 0.0023 17.0 0.5 0.0042 16.2 0.5 1.5 1 0 0 1 1 1 1 CLN3 protein Apt1 PF10351.9 KDO25004.1 - 0.0042 16.0 13.4 0.006 15.5 13.4 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 KDO25004.1 - 0.026 13.0 12.6 0.037 12.5 12.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 PPL5 PF18168.1 KDO25004.1 - 0.055 12.8 8.8 0.097 12.0 8.8 1.3 1 0 0 1 1 1 0 Prim-pol family 5 RAP1 PF07218.11 KDO25004.1 - 0.062 11.6 13.1 0.089 11.1 13.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1168 PF06658.12 KDO25004.1 - 0.063 13.1 28.8 0.21 11.4 28.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SAGA-Tad1 PF12767.7 KDO25004.1 - 0.082 12.6 11.1 0.14 11.9 11.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3537 PF12056.8 KDO25004.1 - 0.13 11.0 1.0 0.27 10.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) TFIIF_alpha PF05793.12 KDO25004.1 - 0.31 9.6 34.4 0.61 8.6 34.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 KDO25004.1 - 0.4 9.4 14.5 0.73 8.5 14.5 1.4 1 0 0 1 1 1 0 Presenilin YL1 PF05764.13 KDO25004.1 - 0.52 10.4 32.4 0.98 9.5 32.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein NARP1 PF12569.8 KDO25004.1 - 0.64 8.9 25.4 1.2 8.0 25.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ndc1_Nup PF09531.10 KDO25004.1 - 0.7 8.5 9.6 0.93 8.1 9.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM70 PF14967.6 KDO25004.1 - 0.75 9.2 0.0 0.75 9.2 0.0 2.2 2 0 0 2 2 2 0 FAM70 protein DUF883 PF05957.13 KDO25004.1 - 1.4 9.6 9.3 6.4 7.4 9.3 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Atrophin-1 PF03154.15 KDO25004.1 - 3.2 5.9 30.0 4.3 5.5 30.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family EMC3_TMCO1 PF01956.16 KDO25004.1 - 3.9 7.2 10.6 9.9 5.9 10.6 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FAM60A PF15396.6 KDO25004.1 - 5.1 7.0 30.8 3.4e+02 1.1 30.8 2.6 1 1 0 1 1 1 0 Protein Family FAM60A Rrn6 PF10214.9 KDO25004.1 - 7.2 5.0 20.5 13 4.1 20.5 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LRR_4 PF12799.7 KDO25005.1 - 0.016 15.6 0.6 9.1 6.9 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO25007.1 - 0.019 15.0 3.7 0.037 14.1 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat ETS_PEA3_N PF04621.13 KDO25008.1 - 0.29 11.0 2.1 0.44 10.4 0.1 1.9 2 0 0 2 2 2 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Ank_2 PF12796.7 KDO25009.1 - 0.0018 18.8 1.7 0.25 12.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) FAM221 PF14753.6 KDO25009.1 - 0.047 13.3 2.8 0.073 12.6 2.8 1.2 1 0 0 1 1 1 0 Protein FAM221A/B Ank_3 PF13606.6 KDO25010.1 - 0.081 13.5 0.0 84 4.3 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KDO25013.1 - 0.0024 18.2 0.3 38 5.3 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 KDO25013.1 - 0.0043 17.6 1.3 0.67 10.6 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25013.1 - 0.038 14.6 1.0 12 6.6 0.1 3.9 3 1 0 3 3 3 0 Ankyrin repeats (many copies) dNK PF01712.19 KDO25014.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Mad3_BUB1_I PF08311.12 KDO25016.1 - 7.9e-40 135.7 2.4 1.5e-39 134.8 2.4 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KDO25016.1 - 0.00085 19.5 0.2 0.0017 18.5 0.2 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein DUF3245 PF11595.8 KDO25016.1 - 0.15 12.6 3.9 4.9 7.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Pkinase PF00069.25 KDO25017.1 - 3.8e-15 56.0 0.0 1.7e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25017.1 - 0.0014 18.0 0.0 0.0029 16.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO25017.1 - 0.043 13.2 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHDPS PF00701.22 KDO25018.1 - 2.1e-71 240.0 0.3 2.4e-71 239.8 0.3 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 KDO25018.1 - 0.011 15.7 0.1 0.028 14.4 0.1 1.7 1 1 0 1 1 1 0 PA domain RraA-like PF03737.15 KDO25018.1 - 0.026 14.7 0.4 0.044 14.0 0.4 1.3 1 0 0 1 1 1 0 Aldolase/RraA WW PF00397.26 KDO25019.1 - 8.2e-21 73.8 7.2 3.9e-10 39.6 0.5 2.2 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KDO25019.1 - 0.00011 22.4 2.1 0.29 11.4 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 KDO25019.1 - 0.00062 19.6 0.3 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 PQQ enzyme repeat WD40_3 PF15911.5 KDO25019.1 - 0.0007 19.5 0.0 0.52 10.3 0.0 2.3 2 1 0 2 2 2 2 WD domain, G-beta repeat CBAH PF02275.18 KDO25019.1 - 0.12 12.0 0.1 8.4 5.9 0.0 2.0 2 0 0 2 2 2 0 Linear amide C-N hydrolases, choloylglycine hydrolase family PDEase_I PF00233.19 KDO25021.1 - 2.8e-62 210.6 0.3 4.6e-62 209.8 0.3 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 KDO25021.1 - 1.2e-09 38.1 0.0 3.2e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 KDO25021.1 - 0.0017 17.6 2.8 0.0045 16.2 2.8 1.7 1 0 0 1 1 1 1 Ion transport protein DUF2616 PF11077.8 KDO25021.1 - 0.099 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Rieske_2 PF13806.6 KDO25022.1 - 1.1e-10 41.3 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KDO25022.1 - 3.4e-10 39.7 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DNA_pol_E_B PF04042.16 KDO25023.1 - 8.6e-47 159.2 1.4 1.3e-46 158.6 1.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 KDO25023.1 - 0.0022 18.3 0.1 0.0054 17.0 0.1 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF3228 PF11539.8 KDO25023.1 - 0.049 13.1 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Chromo_2 PF18704.1 KDO25025.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 SR-25 PF10500.9 KDO25027.1 - 0.00093 18.9 67.2 0.00093 18.9 67.2 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein WD40 PF00400.32 KDO25028.1 - 2.3e-33 113.7 16.8 2.2e-07 31.4 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25028.1 - 1.5e-05 25.2 0.5 3.3 8.1 0.0 4.8 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO25028.1 - 5.3e-05 22.7 0.4 0.0003 20.2 0.2 2.2 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 KDO25028.1 - 0.1 11.2 1.7 5.7 5.5 0.1 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KDO25028.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Hira PF07569.11 KDO25029.1 - 0.0079 15.9 0.3 26 4.5 0.0 4.1 3 1 1 4 4 4 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 KDO25029.1 - 0.028 14.7 0.1 61 4.0 0.0 4.2 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO25029.1 - 0.06 14.2 6.0 3.2 8.8 0.1 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat F-box PF00646.33 KDO25029.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 F-box domain PQQ_2 PF13360.6 KDO25029.1 - 0.31 10.6 4.2 8.3 5.9 0.6 2.6 1 1 2 3 3 3 0 PQQ-like domain Alb1 PF09135.11 KDO25030.1 - 0.14 13.0 1.8 0.16 12.9 0.7 1.7 2 0 0 2 2 2 0 Alb1 Rtf2 PF04641.12 KDO25031.1 - 1.4e-47 162.3 5.6 5e-47 160.5 5.6 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KDO25031.1 - 0.0034 17.2 1.6 0.93 9.4 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KDO25031.1 - 0.018 15.1 1.3 0.035 14.1 1.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger MMADHC PF10229.9 KDO25031.1 - 0.073 12.8 0.1 0.099 12.4 0.1 1.4 1 1 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein SMC_hinge PF06470.13 KDO25031.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.6 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain TPR_1 PF00515.28 KDO25032.1 - 1e-06 28.3 4.8 0.12 12.3 0.1 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25032.1 - 0.00012 21.9 6.0 11 6.4 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25032.1 - 0.0016 18.5 2.8 3.3 8.2 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25032.1 - 0.022 14.8 4.7 14 6.0 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25032.1 - 0.025 14.3 1.7 30 4.4 0.0 4.5 4 0 0 4 4 4 0 TPR repeat ADH_N PF08240.12 KDO25035.1 - 5.2e-26 90.7 2.1 1e-25 89.7 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KDO25035.1 - 1.2e-23 83.6 0.1 2.1e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KDO25035.1 - 0.0012 18.3 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KDO25035.1 - 0.0018 19.3 0.0 0.0044 18.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KDO25035.1 - 0.0091 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KDO25035.1 - 0.011 15.4 0.2 0.017 14.7 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KDO25035.1 - 0.031 13.6 0.4 0.052 12.8 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-RING_11 PF17123.5 KDO25036.1 - 0.00069 19.3 0.9 0.0016 18.2 0.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KDO25036.1 - 0.0036 17.6 7.5 0.0063 16.8 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO25036.1 - 0.0063 16.5 7.4 0.017 15.2 7.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KDO25036.1 - 0.013 15.7 5.5 0.03 14.6 5.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KDO25036.1 - 0.089 12.7 3.0 0.15 12.0 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 KDO25036.1 - 0.096 12.8 0.3 0.24 11.5 0.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_2 PF13923.6 KDO25036.1 - 0.15 11.9 7.7 0.31 10.9 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO25036.1 - 0.21 11.7 3.3 0.52 10.4 3.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO25036.1 - 0.3 11.1 5.9 0.79 9.7 5.7 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO25036.1 - 0.44 10.5 5.9 0.99 9.3 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO25036.1 - 0.53 10.2 4.1 1.2 9.1 4.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO25036.1 - 0.73 9.5 4.0 4.9 6.9 4.5 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type TPR_14 PF13428.6 KDO25037.1 - 4.9e-05 23.8 11.1 0.45 11.5 0.9 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25037.1 - 0.0011 19.1 6.6 5.8 7.2 1.5 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KDO25037.1 - 0.0025 18.3 2.3 3.5 8.2 0.6 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 KDO25037.1 - 0.046 13.4 0.2 2.7 7.7 0.2 2.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KDO25037.1 - 0.048 14.0 0.1 22 5.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25037.1 - 0.13 12.9 13.8 2.6 8.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25037.1 - 7.6 6.9 8.7 31 4.9 0.3 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat DNA_primase_lrg PF04104.14 KDO25038.1 - 2.3e-45 155.1 0.0 2.8e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Zn-ribbon_8 PF09723.10 KDO25039.1 - 0.13 12.3 0.4 0.27 11.4 0.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 KDO25039.1 - 0.78 10.1 5.1 11 6.4 5.4 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Pkinase PF00069.25 KDO25042.1 - 1e-26 93.9 0.0 1.4e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25042.1 - 3.5e-25 88.8 0.0 4.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25042.1 - 0.00019 20.9 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KDO25043.1 - 7.5e-36 123.8 0.0 9.5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25043.1 - 2.4e-34 118.8 0.0 2.8e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25043.1 - 3.5e-08 33.1 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO25043.1 - 0.00079 18.3 0.1 0.0011 17.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO25043.1 - 0.013 14.9 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KDO25044.1 - 5.9e-33 114.4 0.0 7.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25044.1 - 5.7e-32 111.0 0.0 7.4e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25044.1 - 1.7e-06 27.6 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO25044.1 - 0.0071 15.7 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO25044.1 - 0.02 13.7 0.0 0.045 12.5 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase Glutaredoxin PF00462.24 KDO25045.1 - 1.1e-11 44.8 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Bac_GH3_C PF18034.1 KDO25045.1 - 0.047 13.4 0.0 0.063 13.0 0.0 1.3 1 1 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Methyltransf_16 PF10294.9 KDO25046.1 - 2.7e-25 89.1 0.0 3.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KDO25046.1 - 4.1e-05 24.2 0.1 0.011 16.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO25046.1 - 0.00012 21.9 0.0 0.00072 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO25046.1 - 0.0024 18.6 0.1 1 10.2 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KDO25046.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 KDO25046.1 - 0.13 11.5 0.2 0.38 10.1 0.1 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Peptidase_M30 PF10460.9 KDO25046.1 - 0.15 11.0 0.0 0.52 9.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase M30 PrmA PF06325.13 KDO25046.1 - 0.16 11.4 0.2 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) EF1_GNE PF00736.19 KDO25047.1 - 2.1e-30 104.7 3.4 4.1e-30 103.8 3.4 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain PBP1_TM PF14812.6 KDO25047.1 - 0.0075 16.6 7.6 0.014 15.7 7.6 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-1_beta_acid PF10587.9 KDO25047.1 - 0.026 14.9 10.2 0.026 14.9 10.2 2.7 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Stm1_N PF09598.10 KDO25047.1 - 0.084 13.7 3.2 0.084 13.7 3.2 2.4 2 1 0 2 2 2 0 Stm1 eIF3_subunit PF08597.10 KDO25047.1 - 0.16 11.9 13.9 0.25 11.2 13.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Herpes_UL17 PF04559.12 KDO25047.1 - 0.42 9.4 1.4 0.49 9.2 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein FAM176 PF14851.6 KDO25047.1 - 0.44 10.2 2.7 0.65 9.7 2.7 1.2 1 0 0 1 1 1 0 FAM176 family DUF4203 PF13886.6 KDO25048.1 - 5.1e-22 78.5 38.8 5.1e-22 78.5 38.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) Utp11 PF03998.13 KDO25049.1 - 1.9e-69 234.3 16.6 2.2e-69 234.1 16.6 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KDO25049.1 - 0.12 11.6 0.9 0.32 10.3 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4798 PF16055.5 KDO25049.1 - 8.2 6.7 10.0 0.35 11.1 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4798) 60KD_IMP PF02096.20 KDO25050.1 - 2.4e-15 56.8 0.2 3.3e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Pkinase PF00069.25 KDO25051.1 - 5.7e-68 229.1 0.0 7.5e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25051.1 - 4e-29 101.7 0.0 6.6e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO25051.1 - 0.0058 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO25051.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO25051.1 - 0.034 14.1 2.0 0.64 9.9 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO25051.1 - 0.038 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PH PF00169.29 KDO25051.1 - 0.048 14.2 0.1 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 PH domain Gal-3-0_sulfotr PF06990.11 KDO25052.1 - 0.16 10.8 1.5 0.27 10.1 1.5 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Helicase_C PF00271.31 KDO25053.1 - 7.3e-30 103.6 0.1 2.6e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO25053.1 - 8.3e-24 84.3 0.1 1.7e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KDO25053.1 - 0.00076 19.5 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L4 PF00573.22 KDO25053.1 - 0.088 12.5 2.9 0.2 11.4 2.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family NOA36 PF06524.12 KDO25053.1 - 0.33 10.2 5.4 0.68 9.2 5.4 1.5 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KDO25053.1 - 0.4 11.1 13.9 0.9 10.0 13.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.18 KDO25053.1 - 7.3 6.4 14.4 0.24 11.2 8.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region DUF4746 PF15928.5 KDO25053.1 - 7.9 5.8 8.7 16 4.8 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC27 PF09507.10 KDO25053.1 - 8.6 5.6 23.6 0.086 12.2 15.1 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Ammonium_transp PF00909.21 KDO25056.1 - 8.2e-96 321.1 24.1 8.2e-96 321.1 24.1 1.6 2 0 0 2 2 2 1 Ammonium Transporter Family DUF543 PF04418.12 KDO25056.1 - 5.9 6.9 8.4 3.5 7.7 1.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF543) Cyclin_N PF00134.23 KDO25057.1 - 1.2e-06 28.3 0.3 1.8e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain NOA36 PF06524.12 KDO25057.1 - 1.7 7.9 6.0 2.5 7.4 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein GFRP PF06399.13 KDO25058.1 - 6.1e-30 102.9 0.1 6.7e-30 102.8 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF4337 PF14235.6 KDO25059.1 - 0.034 14.3 0.6 0.073 13.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MFS_1 PF07690.16 KDO25060.1 - 1.3e-12 47.3 53.4 4e-08 32.6 33.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily ABC_trans_CmpB PF06541.11 KDO25061.1 - 0.073 13.3 0.3 0.073 13.3 0.3 2.3 2 0 0 2 2 2 0 Putative ABC-transporter type IV HPS3_N PF14761.6 KDO25062.1 - 2.5e-07 30.4 0.4 0.017 14.7 0.0 3.1 2 1 1 3 3 3 2 Hermansky-Pudlak syndrome 3 Carla_C4 PF01623.17 KDO25062.1 - 0.05 13.6 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein V-SNARE_C PF12352.8 KDO25064.1 - 2.3e-14 53.4 6.7 3.9e-14 52.7 6.7 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KDO25064.1 - 4.1e-08 33.5 0.7 4.1e-08 33.5 0.7 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KDO25064.1 - 0.0028 17.6 1.9 0.015 15.2 1.9 2.2 1 1 1 2 2 2 1 Sec20 T6PP_N PF18572.1 KDO25064.1 - 0.082 12.7 2.0 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Ank PF00023.30 KDO25065.1 - 1.5e-15 56.8 2.3 1.5e-05 25.2 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KDO25065.1 - 7.6e-15 55.3 0.1 1.2e-06 29.0 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO25065.1 - 2.9e-12 45.6 0.1 0.012 16.1 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO25065.1 - 6.9e-12 45.4 1.0 0.0028 17.9 0.0 5.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25065.1 - 4.5e-11 43.1 0.5 0.76 10.4 0.0 4.8 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Siva PF05458.12 KDO25065.1 - 0.0082 15.8 2.2 0.016 14.9 2.2 1.4 1 0 0 1 1 1 1 Cd27 binding protein (Siva) FYVE PF01363.21 KDO25065.1 - 0.014 15.5 11.0 0.093 12.9 11.0 2.2 1 1 0 1 1 1 0 FYVE zinc finger SpoU_methylase PF00588.19 KDO25066.1 - 1.3e-15 57.8 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Arfaptin PF06456.13 KDO25066.1 - 0.023 14.3 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Arfaptin-like domain RCC1 PF00415.18 KDO25067.1 - 1.1e-29 102.8 16.5 1.5e-14 54.4 0.0 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO25067.1 - 6.7e-19 67.2 10.5 1.3e-07 31.2 0.1 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat zf-RING_2 PF13639.6 KDO25068.1 - 7.2e-12 45.4 7.3 1.5e-11 44.5 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO25068.1 - 7.3e-09 35.8 4.7 1.7e-08 34.6 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO25068.1 - 6.6e-08 32.3 8.0 1.2e-07 31.5 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO25068.1 - 4.4e-06 26.3 6.3 4.4e-06 26.3 6.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger Ank_2 PF12796.7 KDO25068.1 - 2.2e-05 24.9 0.5 0.002 18.7 0.5 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) zf-ANAPC11 PF12861.7 KDO25068.1 - 4.7e-05 23.4 7.1 0.00017 21.6 7.0 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO25068.1 - 6.4e-05 22.7 8.4 0.00014 21.6 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO25068.1 - 0.00038 20.3 7.1 0.00073 19.4 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO25068.1 - 0.0023 17.9 7.5 0.0045 16.9 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO25068.1 - 0.0032 17.5 9.9 0.0065 16.5 9.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KDO25068.1 - 0.019 14.6 11.0 0.039 13.6 11.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_3 PF13606.6 KDO25068.1 - 0.14 12.8 0.2 1.2 9.9 0.0 2.7 3 0 0 3 3 2 0 Ankyrin repeat Ank PF00023.30 KDO25068.1 - 0.23 12.0 1.0 3.1 8.4 0.1 2.8 3 0 0 3 3 2 0 Ankyrin repeat zf-C3H2C3 PF17122.5 KDO25068.1 - 0.84 9.7 8.4 2 8.6 8.4 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KDO25068.1 - 1 9.6 6.2 2.4 8.4 6.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KDO25068.1 - 3.3 8.0 6.6 7.7 6.8 6.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 KDO25069.1 - 2.3e-40 137.1 10.2 4.6e-14 52.8 1.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25069.1 - 5.7e-37 125.6 13.7 6.1e-11 42.6 0.1 6.3 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25069.1 - 2.1e-32 107.5 3.4 0.0031 17.9 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KDO25069.1 - 8.5e-27 92.4 16.2 1e-05 25.7 0.4 7.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KDO25069.1 - 2.5e-23 81.8 15.4 3.8e-08 33.4 0.1 7.2 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ser_hydrolase PF06821.13 KDO25069.1 - 0.022 14.6 3.7 0.036 13.9 0.3 2.7 1 1 2 3 3 3 0 Serine hydrolase Abhydrolase_6 PF12697.7 KDO25070.1 - 1.2e-13 52.2 8.6 1.8e-13 51.6 8.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO25070.1 - 2.8e-06 26.8 0.0 3.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO25070.1 - 0.00064 19.4 0.1 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold HA PF03457.14 KDO25071.1 - 1.4e-21 76.5 0.0 8.5e-09 35.6 0.0 4.3 3 1 0 3 3 3 3 Helicase associated domain Pyrophosphatase PF00719.19 KDO25072.1 - 2.3e-45 154.3 0.2 4e-45 153.5 0.2 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase PH PF00169.29 KDO25072.1 - 5.6e-12 46.1 0.1 1.2e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO25072.1 - 3.8e-06 27.3 0.6 0.0001 22.7 0.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain EF-hand_7 PF13499.6 KDO25072.1 - 0.00017 22.0 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO25072.1 - 0.00034 20.3 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KDO25072.1 - 0.002 17.5 0.0 0.0051 16.3 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KDO25072.1 - 0.051 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 EF hand PH_15 PF17339.2 KDO25072.1 - 0.082 12.8 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 PH domain Aa_trans PF01490.18 KDO25073.1 - 6.7e-08 31.6 3.1 8.6e-07 28.0 3.1 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SPC12 PF06645.13 KDO25073.1 - 0.045 13.8 1.0 0.045 13.8 1.0 2.7 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4064 PF13273.6 KDO25073.1 - 0.098 12.9 0.4 0.098 12.9 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Aa_trans PF01490.18 KDO25074.1 - 3.7e-39 134.6 33.3 4.3e-39 134.4 33.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO25074.1 - 2.9e-12 46.4 22.6 4.4e-12 45.7 22.6 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family HILPDA PF15220.6 KDO25074.1 - 0.41 10.8 0.1 0.41 10.8 0.1 2.7 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated Med29 PF11568.8 KDO25075.1 - 0.0073 16.5 0.1 0.0085 16.3 0.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 29 RPN6_N PF18055.1 KDO25075.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain CENP-K PF11802.8 KDO25075.1 - 0.061 12.9 0.3 3.7 7.0 0.0 2.0 1 1 1 2 2 2 0 Centromere-associated protein K RPW8 PF05659.11 KDO25075.1 - 0.062 13.0 0.3 1.1 9.0 0.5 2.1 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec5 PF15469.6 KDO25075.1 - 0.069 12.9 0.2 0.11 12.3 0.2 1.4 1 1 0 1 1 1 0 Exocyst complex component Sec5 PHO4 PF01384.20 KDO25076.1 - 2.1 7.3 5.2 3.3 6.7 5.1 1.4 1 1 0 1 1 1 0 Phosphate transporter family MFS_1 PF07690.16 KDO25078.1 - 1.1e-07 31.2 35.7 1.9e-07 30.4 15.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Nuc_sug_transp PF04142.15 KDO25078.1 - 0.07 12.3 2.2 0.099 11.8 0.7 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter MFS_1 PF07690.16 KDO25079.1 - 2.3e-14 53.1 40.4 1.4e-08 34.0 15.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Snapin_Pallidin PF14712.6 KDO25081.1 - 3.6e-11 43.3 2.6 5.3e-11 42.8 2.6 1.3 1 0 0 1 1 1 1 Snapin/Pallidin Sde2_N_Ubi PF13019.6 KDO25081.1 - 0.15 11.9 2.5 0.35 10.7 0.8 2.0 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain YabA PF06156.13 KDO25081.1 - 2.6 8.7 4.2 2.2 8.9 0.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Homeodomain PF00046.29 KDO25082.1 - 3.4e-07 30.0 0.3 8.2e-07 28.8 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KDO25082.1 - 0.0028 17.5 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain SWIM PF04434.17 KDO25083.1 - 0.0051 16.4 0.1 0.0051 16.4 0.1 1.8 2 0 0 2 2 2 1 SWIM zinc finger MULE PF10551.9 KDO25084.1 - 0.00025 21.4 0.6 0.0019 18.5 0.6 2.2 1 1 0 1 1 1 1 MULE transposase domain Ank_2 PF12796.7 KDO25085.1 - 6.8e-59 196.4 19.4 8.5e-13 48.7 0.5 7.3 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25085.1 - 2.9e-56 187.1 11.6 1.8e-10 41.2 0.1 8.0 6 1 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25085.1 - 2.6e-45 147.1 17.8 0.0001 22.5 0.1 13.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KDO25085.1 - 4e-41 138.5 32.9 5.3e-08 33.0 0.1 11.4 2 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KDO25085.1 - 2.2e-33 113.2 39.6 0.0019 18.6 0.1 12.6 13 0 0 13 13 13 10 Ankyrin repeat Ank_2 PF12796.7 KDO25086.1 - 4.6e-56 187.4 38.0 2.3e-13 50.5 1.6 6.8 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25086.1 - 9.1e-49 163.2 10.5 2.7e-09 37.4 0.2 10.0 6 4 3 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO25086.1 - 7.7e-39 131.2 17.7 9.2e-08 32.2 0.1 8.7 5 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25086.1 - 3.8e-37 122.1 14.4 0.089 13.4 0.0 13.9 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 KDO25086.1 - 1.8e-36 123.0 37.9 3.3e-05 24.1 0.1 13.9 15 0 0 15 15 15 11 Ankyrin repeat Ank_2 PF12796.7 KDO25087.1 - 4.1e-67 222.8 39.7 3.8e-13 49.8 1.0 7.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25087.1 - 1.7e-56 187.9 23.8 6e-10 39.5 0.1 9.3 2 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25087.1 - 2.3e-45 147.3 28.2 0.00021 21.4 0.1 14.3 15 0 0 15 15 15 12 Ankyrin repeat Ank PF00023.30 KDO25087.1 - 7e-39 130.6 51.7 6.7e-05 23.2 0.5 14.0 13 1 1 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 KDO25087.1 - 2.2e-37 126.6 36.2 1.1e-06 28.8 0.3 10.8 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Phosphonate-bd PF12974.7 KDO25087.1 - 0.029 14.0 1.3 1.6 8.2 0.0 3.2 3 1 0 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Imm_superinfect PF14373.6 KDO25087.1 - 0.28 11.1 7.4 1.4e+02 2.5 0.0 6.0 5 0 0 5 5 5 0 Superinfection immunity protein Ank_2 PF12796.7 KDO25088.1 - 1.5e-63 211.4 25.2 7.9e-15 55.2 0.1 6.0 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25088.1 - 3e-49 164.8 17.5 5.4e-08 33.2 0.1 9.8 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO25088.1 - 5.3e-33 112.6 28.5 1.7e-08 34.6 0.1 9.4 2 2 9 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25088.1 - 3.1e-32 107.0 19.8 0.028 14.9 0.0 13.0 13 0 0 13 13 13 9 Ankyrin repeat Ank PF00023.30 KDO25088.1 - 1.4e-31 107.6 44.9 0.00024 21.4 0.3 12.9 12 1 1 13 13 13 10 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO25088.1 - 3.1e-27 95.5 0.0 1.3e-26 93.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25088.1 - 1.8e-21 76.7 0.0 4.8e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KDO25089.1 - 3e-41 139.9 4.6 1.5e-10 41.5 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KDO25089.1 - 8.9e-37 126.8 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KDO25089.1 - 1.1e-34 118.3 3.9 2e-07 31.4 0.0 7.2 4 2 3 8 8 8 6 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO25089.1 - 1.4e-34 119.7 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KDO25089.1 - 8.9e-26 87.1 9.8 0.0035 17.7 0.0 11.0 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 KDO25089.1 - 1.4e-20 72.8 18.9 0.0014 19.0 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KDO25089.1 - 3.2e-20 71.9 14.6 0.00014 22.1 0.0 8.0 2 1 8 10 10 10 7 Ankyrin repeats (many copies) RPN7 PF10602.9 KDO25091.1 - 2.1e-51 174.1 2.5 4.3e-51 173.1 1.7 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KDO25091.1 - 2.6e-14 53.6 0.0 7.1e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain ComR_TPR PF18710.1 KDO25091.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.9 1 1 0 1 1 1 1 ComR tetratricopeptide MFS_1 PF07690.16 KDO25092.1 - 9.8e-10 37.9 36.3 1.1e-08 34.5 19.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KDO25093.1 - 5.3e-51 171.1 24.5 3.8e-14 53.0 0.5 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25093.1 - 1.3e-34 118.1 6.1 3.9e-08 33.7 0.0 6.7 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25093.1 - 1.8e-33 110.8 12.2 0.00011 22.3 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KDO25093.1 - 5e-26 90.0 21.8 0.0028 18.0 0.4 9.1 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KDO25093.1 - 2e-22 78.9 20.5 1.8e-06 28.1 0.2 7.9 3 3 5 8 8 8 6 Ankyrin repeats (many copies) DUF1843 PF08898.10 KDO25093.1 - 0.25 11.9 5.6 0.97 10.0 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) MFS_1 PF07690.16 KDO25094.1 - 5.8e-11 41.9 40.9 1.6e-07 30.6 18.4 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily NUC130_3NT PF08158.12 KDO25095.1 - 0.11 12.9 0.4 22 5.5 0.1 3.6 3 0 0 3 3 3 0 NUC130/3NT domain Herpes_US9 PF06072.11 KDO25096.1 - 0.15 12.0 1.0 0.44 10.5 0.2 2.3 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 YrhC PF14143.6 KDO25096.1 - 0.16 12.1 0.4 0.62 10.2 0.4 2.0 1 0 0 1 1 1 0 YrhC-like protein WW PF00397.26 KDO25099.1 - 3.6e-06 26.9 1.2 7.4e-06 25.9 1.2 1.5 1 0 0 1 1 1 1 WW domain CENP-B_dimeris PF09026.10 KDO25099.1 - 0.051 14.0 9.1 0.077 13.4 9.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 KDO25101.1 - 2.1e-19 69.9 4.6 3.6e-09 37.1 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25101.1 - 2.2e-15 56.8 5.5 0.00095 19.7 0.2 5.1 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO25101.1 - 1.4e-13 50.7 4.1 0.0075 16.6 0.1 6.5 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25101.1 - 2.9e-09 36.4 1.5 7.5 7.5 0.0 7.0 6 1 1 7 7 7 3 Ankyrin repeat DUF5049 PF16468.5 KDO25101.1 - 0.00068 19.5 0.6 17 5.4 0.0 4.9 2 2 3 5 5 5 1 Domain of unknown function (DUF5049) Ank PF00023.30 KDO25101.1 - 0.0043 17.4 4.5 55 4.5 0.2 5.5 2 1 2 4 4 4 0 Ankyrin repeat VbhA PF18495.1 KDO25101.1 - 0.11 12.4 0.3 0.69 9.8 0.1 2.5 2 0 0 2 2 2 0 Antitoxin VbhA IMS PF00817.20 KDO25102.1 - 3.4e-41 140.7 4.6 1.7e-40 138.4 1.0 2.7 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.8 KDO25102.1 - 1e-10 42.4 3.0 1.3e-10 42.0 0.2 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KDO25102.1 - 8.9e-07 28.9 0.2 1.9e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 KDO25102.1 - 2.2e-05 24.2 3.6 0.095 12.3 0.4 3.2 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C2H2_4 PF13894.6 KDO25102.1 - 0.0022 18.7 5.8 0.044 14.6 0.1 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KDO25102.1 - 0.0078 16.7 3.2 2 8.9 0.1 3.7 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KDO25102.1 - 0.035 14.4 10.2 3.9 7.8 0.3 3.8 4 0 0 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KDO25102.1 - 0.11 12.6 5.9 20 5.4 0.2 3.6 3 0 0 3 3 3 0 Zinc ribbon domain BAF PF02961.14 KDO25102.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Barrier to autointegration factor zf-U11-48K PF05253.12 KDO25102.1 - 0.13 12.2 0.4 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger zf-ribbon_3 PF13248.6 KDO25102.1 - 0.55 9.7 8.2 10 5.7 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-WRNIP1_ubi PF18279.1 KDO25102.1 - 0.77 10.5 7.2 6.1 7.7 0.5 3.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Rad50_zn_hook PF04423.14 KDO25102.1 - 2.2 8.2 7.7 11 6.0 0.1 3.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KDO25102.1 - 2.3 8.1 10.1 6.8 6.6 0.5 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C2H2 PF00096.26 KDO25102.1 - 5.3 7.7 7.0 5 7.8 0.1 3.5 3 1 0 3 3 3 0 Zinc finger, C2H2 type PLRV_ORF5 PF01690.17 KDO25103.1 - 0.76 8.4 2.5 1.2 7.8 2.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ion_trans PF00520.31 KDO25104.1 - 3.4e-41 141.1 37.7 5.4e-22 78.2 14.9 2.3 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 KDO25104.1 - 2.1e-23 82.1 17.3 3.9e-13 49.2 7.7 3.3 2 1 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 KDO25104.1 - 4e-15 55.7 0.2 1.5e-06 28.1 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain IRK PF01007.20 KDO25104.1 - 0.041 13.7 13.6 0.21 11.4 5.2 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Ank_5 PF13857.6 KDO25106.1 - 2.2e-12 46.9 9.9 0.0011 19.3 0.2 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25106.1 - 6.3e-12 45.8 6.4 8.7e-06 26.2 0.3 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO25106.1 - 8.3e-11 42.3 5.4 2.5e-05 24.8 0.7 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO25106.1 - 1.8e-07 30.9 2.7 5.7 7.8 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KDO25106.1 - 0.05 14.1 2.4 27 5.4 0.2 4.5 2 1 1 3 3 3 0 Ankyrin repeat YmaF PF12788.7 KDO25106.1 - 0.26 11.9 2.1 0.62 10.6 1.5 1.9 1 1 1 2 2 2 0 YmaF family Pkinase_Tyr PF07714.17 KDO25107.1 - 1e-16 61.0 0.2 3.3e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO25107.1 - 4.7e-12 45.8 0.0 2.3e-09 37.0 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 KDO25107.1 - 1e-06 28.4 5.6 1e-06 28.4 5.6 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO25107.1 - 1.6e-05 25.2 9.4 0.00014 22.2 2.9 3.0 1 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO25107.1 - 7.4e-05 22.5 2.3 0.33 11.1 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KDO25107.1 - 0.0077 16.6 0.8 76 4.5 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat RNA_pol PF00940.19 KDO25107.1 - 0.035 13.0 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FTCD_N PF07837.12 KDO25107.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain Fe_hyd_lg_C PF02906.14 KDO25107.1 - 0.17 11.5 0.2 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Acetyltransf_2 PF00797.17 KDO25109.1 - 4.7e-46 157.5 0.0 1.1e-45 156.3 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KDO25109.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily EFG_II PF14492.6 KDO25110.1 - 1.1e-26 92.8 0.1 2.5e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KDO25110.1 - 1.9e-20 72.7 0.0 5.2e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 KDO25110.1 - 5.2e-19 68.5 0.8 5.1e-12 45.7 0.7 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KDO25110.1 - 7.2e-14 51.6 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 KDO25110.1 - 5.4e-09 36.0 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KDO25110.1 - 1.4e-07 31.8 0.0 3.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AvrPtoB_bdg PF16847.5 KDO25110.1 - 0.0086 16.5 0.0 25 5.4 0.0 3.6 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KDO25110.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase HGTP_anticodon2 PF12745.7 KDO25110.1 - 0.17 11.3 0.0 0.69 9.4 0.0 1.8 1 1 0 2 2 2 0 Anticodon binding domain of tRNAs WASH-7_N PF14745.6 KDO25112.1 - 2.3e-70 237.7 3.0 3e-70 237.3 3.0 1.1 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal DUF4090 PF13319.6 KDO25112.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) DUF4611 PF15387.6 KDO25112.1 - 1.4 9.2 5.9 0.52 10.6 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LRR_4 PF12799.7 KDO25113.1 - 4.6e-07 30.0 1.7 0.053 14.0 0.3 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO25113.1 - 0.00017 21.3 0.5 0.0013 18.5 0.4 2.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KDO25113.1 - 0.0049 16.8 0.2 2.5 8.4 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 KDO25113.1 - 0.67 10.7 6.6 23 6.0 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat ParcG PF10274.9 KDO25116.1 - 8.3e-42 143.4 0.0 1.3e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Parkin co-regulated protein TPR_2 PF07719.17 KDO25117.1 - 1.2e-21 75.0 14.9 0.00016 21.5 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25117.1 - 1.2e-20 72.4 11.5 0.0059 16.4 0.1 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25117.1 - 9.3e-13 47.6 5.4 0.0013 18.4 0.0 5.4 4 1 1 5 5 5 3 TPR repeat TPR_12 PF13424.6 KDO25117.1 - 1.1e-12 48.1 26.0 0.00054 20.2 0.1 7.1 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25117.1 - 6e-09 35.4 5.7 0.001 19.1 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25117.1 - 6.5e-09 36.3 22.3 0.03 15.0 2.2 6.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KDO25117.1 - 8.8e-09 35.2 11.6 0.043 14.2 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25117.1 - 8.8e-07 29.3 23.8 0.17 12.4 0.8 5.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25117.1 - 0.00016 22.2 30.8 0.55 11.2 0.3 9.1 5 2 5 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO25117.1 - 0.00059 19.9 18.0 0.047 13.8 1.2 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25117.1 - 0.00081 19.2 14.1 0.14 12.0 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 KDO25117.1 - 0.0027 17.2 2.6 0.53 9.7 0.0 2.6 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KDO25117.1 - 0.0037 17.2 6.5 0.25 11.5 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25117.1 - 0.34 11.2 16.2 3.7 7.9 1.2 5.0 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KDO25117.1 - 0.93 9.2 8.0 5.9 6.6 0.0 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 KDO25118.1 - 6.8e-20 69.5 13.0 1.9e-05 24.4 0.6 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25118.1 - 9e-20 69.6 11.3 6.1e-06 25.8 0.4 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25118.1 - 2.9e-12 47.0 15.4 0.017 15.7 0.1 5.4 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25118.1 - 8.4e-10 38.2 13.4 0.0065 16.1 0.3 5.2 5 1 1 6 6 6 4 TPR repeat TPR_9 PF13371.6 KDO25118.1 - 3.2e-09 36.8 17.3 0.00086 19.4 0.3 4.8 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25118.1 - 4.8e-07 30.0 15.7 0.0011 19.2 0.1 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KDO25118.1 - 5.3e-07 29.9 10.3 0.23 12.2 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25118.1 - 8.8e-07 28.7 7.4 3.5 8.1 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25118.1 - 1.1e-06 28.9 8.6 2.4 9.2 0.6 5.8 3 3 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25118.1 - 1.3e-05 25.3 14.5 0.0057 16.8 1.7 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KDO25118.1 - 3.1e-05 24.1 2.7 0.92 10.0 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25118.1 - 0.00057 20.3 6.5 1.6 9.3 0.0 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat DUF1358 PF07096.11 KDO25118.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) TPR_8 PF13181.6 KDO25119.1 - 0.027 14.7 0.3 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25119.1 - 0.098 12.8 1.9 0.16 12.1 0.4 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25120.1 - 0.0026 17.8 0.3 0.16 12.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO25120.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIIE_beta PF02186.15 KDO25122.1 - 4.2e-11 43.0 0.1 9.4e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 KDO25122.1 - 3.9e-10 39.3 0.0 9.2e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 FaeA PF04703.12 KDO25122.1 - 0.091 13.2 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 FaeA-like protein BSD PF03909.17 KDO25125.1 - 8.5e-12 44.9 0.1 1.3e-09 37.9 0.1 2.6 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KDO25125.1 - 0.0019 18.5 0.1 0.018 15.4 0.0 2.5 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain 14-3-3 PF00244.20 KDO25126.1 - 3.4e-85 285.1 4.0 3.9e-85 284.9 4.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_7 PF13176.6 KDO25126.1 - 0.019 15.0 4.0 4.3 7.6 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25126.1 - 0.057 13.7 3.7 0.51 10.7 0.3 3.1 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25126.1 - 0.15 12.3 0.7 3.6 8.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 KDO25127.1 - 9.9e-19 67.8 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Herpes_TK PF00693.18 KDO25127.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus 14-3-3 PF00244.20 KDO25128.1 - 7.3e-59 199.0 0.0 8.2e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1428 PF07237.11 KDO25128.1 - 0.098 12.9 0.2 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) TPR_12 PF13424.6 KDO25130.1 - 1.7e-25 89.1 22.3 3e-08 33.8 0.8 5.2 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25130.1 - 3.7e-18 64.8 6.1 1.7e-06 27.7 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25130.1 - 7.4e-06 25.7 5.9 0.18 12.0 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25130.1 - 1.6e-05 24.7 0.3 4.4 7.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25130.1 - 1.8e-05 24.4 3.0 0.69 10.1 0.1 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25130.1 - 5.1e-05 23.8 5.9 0.065 13.9 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO25130.1 - 6.9e-05 23.1 6.9 0.19 12.5 0.2 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO25130.1 - 0.00035 20.1 5.1 0.00035 20.1 5.1 2.7 2 1 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 KDO25130.1 - 0.0014 18.3 0.4 7.6 6.5 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25130.1 - 0.0063 17.0 3.2 0.021 15.4 0.3 3.3 3 1 2 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25130.1 - 0.068 13.4 0.4 1.9 8.8 0.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KDO25130.1 - 0.12 12.7 0.9 0.81 10.1 0.2 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25130.1 - 0.17 12.8 12.2 0.85 10.6 0.2 5.7 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF1126 PF06565.12 KDO25131.1 - 2.6e-86 284.3 1.0 1e-33 115.3 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain Cyt-b5 PF00173.28 KDO25132.1 - 2.1e-20 72.6 0.1 2.9e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vps36-NZF-N PF16988.5 KDO25133.1 - 0.045 13.1 1.2 0.077 12.4 1.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_ribbon_SprT PF17283.2 KDO25133.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-RanBP PF00641.18 KDO25133.1 - 0.22 10.9 5.6 0.4 10.0 5.6 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Cyt-b5 PF00173.28 KDO25134.1 - 8.3e-21 73.9 0.1 1.1e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2996 PF11210.8 KDO25134.1 - 0.023 15.1 0.0 0.026 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) NIF PF03031.18 KDO25135.1 - 1.7e-55 187.1 0.1 2.3e-55 186.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PAN_4 PF14295.6 KDO25136.1 - 0.53 10.2 5.6 1.9 8.4 1.3 2.5 2 0 0 2 2 2 0 PAN domain YbfN PF13982.6 KDO25136.1 - 1.9 8.8 6.4 1.9 8.8 0.8 2.6 2 1 0 3 3 3 0 YbfN-like lipoprotein Peptidase_S8 PF00082.22 KDO25137.1 - 1.1e-36 126.6 0.0 2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family NPL PF17800.1 KDO25138.1 - 3.3e-11 43.7 0.2 3.3e-11 43.7 0.2 1.5 2 0 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 KDO25138.1 - 0.0021 18.5 0.2 0.004 17.6 0.2 1.4 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain LRR_6 PF13516.6 KDO25139.1 - 2.1e-07 30.4 0.2 0.0024 17.8 0.1 2.3 2 0 0 2 2 2 2 Leucine Rich repeat LRR_8 PF13855.6 KDO25139.1 - 0.0074 16.0 0.2 0.055 13.2 0.2 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KDO25139.1 - 0.02 15.3 0.1 0.059 13.8 0.1 1.7 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO25139.1 - 0.15 12.7 0.0 19 6.3 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich Repeat 2OG-FeII_Oxy_3 PF13640.6 KDO25140.1 - 8.2e-14 52.3 0.0 1.9e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LicD PF04991.13 KDO25142.1 - 2.7e-18 66.9 0.0 2.2e-10 41.1 0.0 2.5 1 1 1 2 2 2 2 LicD family MSA-2c PF12238.8 KDO25143.1 - 0.23 11.5 1.9 0.49 10.4 1.9 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Mid1 PF12929.7 KDO25144.1 - 1.1e-16 61.1 15.2 7.8e-13 48.4 6.6 2.0 1 1 1 2 2 2 2 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KDO25144.1 - 0.00059 20.4 9.8 0.0074 16.9 9.8 2.4 1 1 0 1 1 1 1 Fz domain IFT46_B_C PF12317.8 KDO25145.1 - 3.4e-37 128.3 0.0 4.1e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal SKG6 PF08693.10 KDO25147.1 - 0.0015 17.9 2.5 0.0028 17.0 2.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_Tyr PF07714.17 KDO25147.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3153 PF11353.8 KDO25147.1 - 0.11 12.0 2.4 0.54 9.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Pkinase_Tyr PF07714.17 KDO25148.1 - 0.0036 16.6 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KDO25148.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 KDO25148.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KDO25149.1 - 3.3e-45 154.5 0.0 6e-45 153.7 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25149.1 - 7.1e-44 150.0 0.0 9e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO25149.1 - 0.0001 22.3 0.1 0.019 14.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 KDO25149.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC1 family CPBP PF02517.16 KDO25149.1 - 0.064 13.6 1.0 6.2 7.3 0.2 2.4 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Pkinase_fungal PF17667.1 KDO25149.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO25150.1 - 1.3e-46 158.9 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25150.1 - 4.8e-46 157.3 0.0 1.1e-45 156.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KDO25150.1 - 1.9e-06 27.6 4.2 0.0018 18.0 1.6 2.7 2 0 0 2 2 2 2 Leucine rich repeat Pkinase_fungal PF17667.1 KDO25150.1 - 0.0031 16.4 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_4 PF12799.7 KDO25150.1 - 0.009 16.4 13.0 1.5 9.3 2.4 4.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 KDO25150.1 - 0.023 13.6 0.0 0.58 9.0 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KDO25150.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ax_dynein_light PF10211.9 KDO25152.1 - 2e-61 207.2 1.9 2.4e-61 207.0 1.9 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain DUF3206 PF11472.8 KDO25152.1 - 0.018 15.0 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) Metal_resist PF13801.6 KDO25152.1 - 0.044 14.0 6.5 0.13 12.5 0.0 2.7 2 1 1 3 3 3 0 Heavy-metal resistance ZapB PF06005.12 KDO25152.1 - 0.062 13.8 0.8 0.062 13.8 0.8 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF2220 PF09983.9 KDO25152.1 - 0.079 12.3 1.2 0.092 12.1 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Mto2_bdg PF12808.7 KDO25152.1 - 0.18 12.1 0.3 0.18 12.1 0.3 2.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.15 KDO25152.1 - 8 6.3 7.4 2.4 8.0 2.9 2.1 2 0 0 2 2 2 0 Septum formation initiator Abhydrolase_6 PF12697.7 KDO25153.1 - 1.1e-24 88.3 0.1 2.7e-24 87.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO25153.1 - 7.9e-24 84.7 0.5 5.2e-15 55.8 0.1 2.5 2 1 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO25153.1 - 2.6e-15 56.4 0.1 4.7e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KDO25153.1 - 0.0026 17.4 0.0 0.0047 16.6 0.0 1.6 2 0 0 2 2 2 1 Putative esterase UPF0227 PF05728.12 KDO25153.1 - 0.0099 15.8 0.2 0.25 11.3 0.0 2.7 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0227) LIP PF03583.14 KDO25153.1 - 0.015 14.6 0.1 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_4 PF08386.10 KDO25153.1 - 0.015 15.4 0.0 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein DUF676 PF05057.14 KDO25153.1 - 0.028 13.9 0.0 0.061 12.8 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 KDO25153.1 - 0.13 11.9 0.1 3.1 7.4 0.0 2.4 3 0 0 3 3 3 0 PGAP1-like protein Pkinase PF00069.25 KDO25155.1 - 2.1e-45 155.1 0.0 2.9e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25155.1 - 5.3e-44 150.5 0.0 6.8e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO25155.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pex2_Pex12 PF04757.14 KDO25155.1 - 0.041 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Pkinase_fungal PF17667.1 KDO25155.1 - 0.044 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_4 PF12799.7 KDO25155.1 - 0.15 12.5 0.4 9.3 6.8 0.6 2.6 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LapA_dom PF06305.11 KDO25155.1 - 0.16 11.8 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LRR_4 PF12799.7 KDO25156.1 - 7.9e-07 29.3 4.3 0.02 15.3 0.9 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO25156.1 - 0.00011 21.9 0.7 0.0076 16.0 0.3 3.5 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 KDO25156.1 - 0.15 12.2 3.1 25 5.3 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KDO25156.1 - 3.2 8.7 6.2 1.4e+02 3.6 0.5 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 KDO25157.1 - 9.4e-44 149.7 0.0 1.3e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25157.1 - 1.9e-42 145.4 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO25157.1 - 0.026 14.5 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO25157.1 - 0.12 11.7 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like LRR_8 PF13855.6 KDO25157.1 - 0.13 12.0 4.2 0.14 12.0 0.2 2.8 2 1 0 2 2 2 0 Leucine rich repeat Kdo PF06293.14 KDO25157.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 KDO25157.1 - 2.9 8.4 10.5 7.2 7.2 0.2 3.9 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 KDO25158.1 - 2e-48 165.0 0.0 2.6e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25158.1 - 5e-45 153.9 0.0 7e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO25158.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO25159.1 - 3.4e-38 131.4 0.0 4.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25159.1 - 1.2e-37 129.8 0.0 1.8e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 KDO25159.1 - 0.00024 21.4 4.3 0.062 13.7 0.7 3.9 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) APH PF01636.23 KDO25159.1 - 0.052 13.5 0.0 0.22 11.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_8 PF13855.6 KDO25159.1 - 0.17 11.7 2.0 5 7.0 1.6 3.0 1 1 2 3 3 3 0 Leucine rich repeat VPS11_C PF12451.8 KDO25160.1 - 0.077 13.2 1.2 0.077 13.2 1.2 2.2 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FliT PF05400.13 KDO25160.1 - 0.18 12.7 0.4 0.18 12.7 0.4 2.3 1 1 1 2 2 2 0 Flagellar protein FliT DNA_binding_2 PF13724.6 KDO25160.1 - 0.28 11.6 0.3 0.28 11.6 0.3 1.9 1 1 1 2 2 2 0 DNA-binding domain DUF2388 PF09498.10 KDO25161.1 - 8.3 6.5 7.7 5 7.2 1.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2388) Fer4_21 PF14697.6 KDO25163.1 - 0.014 15.5 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain LRR_4 PF12799.7 KDO25164.1 - 0.58 10.7 3.7 4.3 7.9 0.3 3.2 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) His_Phos_1 PF00300.22 KDO25166.1 - 3.7e-16 59.4 0.2 7.9e-16 58.3 0.1 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Proteasome PF00227.26 KDO25167.1 - 1.9e-58 197.1 0.1 2.8e-58 196.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO25167.1 - 7.8e-14 51.0 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2110 PF09883.9 KDO25167.1 - 0.09 12.4 0.4 0.36 10.4 0.1 2.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) AA_kinase PF00696.28 KDO25169.1 - 5.7e-37 127.6 0.1 9.9e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ARL2_Bind_BART PF11527.8 KDO25170.1 - 6.8e-27 93.9 5.4 9.9e-27 93.4 5.4 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Hemocyanin_N PF03722.14 KDO25170.1 - 0.042 14.4 0.0 0.072 13.6 0.0 1.6 1 1 0 1 1 1 0 Hemocyanin, all-alpha domain C-C_Bond_Lyase PF15617.6 KDO25170.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold SNARE_assoc PF09335.11 KDO25172.1 - 2.4e-14 53.9 9.0 2.4e-14 53.9 9.0 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein GSH_synth_ATP PF03917.17 KDO25173.1 - 2.3e-116 388.7 0.0 2.6e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KDO25173.1 - 6.8e-37 126.0 0.0 1.7e-36 124.8 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MCR_alpha PF02249.17 KDO25173.1 - 0.15 12.5 0.1 4.4 7.8 0.1 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain MIP PF00230.20 KDO25179.1 - 7.2e-52 176.3 5.5 9.7e-52 175.9 5.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF5476 PF17570.2 KDO25180.1 - 0.066 13.6 0.0 0.3 11.5 0.0 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5476) GST_N_2 PF13409.6 KDO25183.1 - 2.9e-22 78.8 0.0 8.9e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO25183.1 - 1.4e-12 47.4 0.0 7.2e-12 45.2 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO25183.1 - 1.9e-08 34.4 0.0 3.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO25183.1 - 2.5e-07 30.8 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KDO25183.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO25183.1 - 0.0036 17.7 0.0 0.13 12.6 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4570 PF15134.6 KDO25184.1 - 0.12 12.4 7.1 0.16 12.0 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Ank_2 PF12796.7 KDO25186.1 - 2.5e-120 393.3 31.4 1.4e-16 60.8 0.1 11.4 1 1 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25186.1 - 1.4e-92 302.9 3.2 2e-09 37.8 0.0 14.7 10 4 4 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25186.1 - 8.7e-71 225.4 12.8 0.00078 19.7 0.0 21.1 20 1 1 21 21 21 16 Ankyrin repeat Ank PF00023.30 KDO25186.1 - 6.2e-66 216.1 30.7 2.3e-05 24.6 0.0 20.2 19 2 0 19 19 19 14 Ankyrin repeat Ank_5 PF13857.6 KDO25186.1 - 2e-64 212.8 21.2 1.4e-08 34.8 0.0 14.5 5 4 11 16 16 16 14 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO25186.1 - 1.4e-49 168.9 0.0 3.8e-49 167.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25186.1 - 6.8e-44 150.1 0.0 1.5e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO25186.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO25186.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain D5_N PF08706.11 KDO25186.1 - 0.19 12.0 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 D5 N terminal like Imm_superinfect PF14373.6 KDO25186.1 - 0.19 11.6 8.8 1.1e+02 2.9 0.1 7.0 8 0 0 8 8 8 0 Superinfection immunity protein bMG3 PF11974.8 KDO25186.1 - 1.3 9.1 4.8 11 6.1 0.0 4.5 5 1 0 5 5 5 0 Bacterial alpha-2-macroglobulin MG3 domain Myotub-related PF06602.14 KDO25187.1 - 1.8e-118 395.5 0.0 2.5e-118 395.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KDO25187.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 0 GRAM domain Y_phosphatase PF00102.27 KDO25187.1 - 0.035 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KDO25187.1 - 0.039 13.9 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family EF-hand_7 PF13499.6 KDO25189.1 - 2e-18 66.6 6.3 6.2e-07 29.8 0.1 5.5 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.6 KDO25189.1 - 2.3e-15 56.2 0.6 9.4e-06 25.4 0.0 5.4 5 1 1 6 6 6 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO25189.1 - 3.7e-15 54.3 9.1 0.00015 21.1 0.2 7.4 9 0 0 9 9 9 4 EF hand EF-hand_6 PF13405.6 KDO25189.1 - 4.3e-13 48.1 12.6 0.00017 21.3 0.3 8.0 7 0 0 7 7 7 3 EF-hand domain EF-hand_5 PF13202.6 KDO25189.1 - 3e-08 32.8 1.8 0.0086 15.5 0.1 5.4 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 KDO25189.1 - 0.0022 18.3 0.3 2.4 8.5 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain DZR PF12773.7 KDO25189.1 - 7.1 6.7 7.2 53 3.9 5.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon EF-hand_7 PF13499.6 KDO25190.1 - 1.3e-16 60.7 1.4 4.4e-06 27.0 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO25190.1 - 8.8e-09 34.3 8.1 0.00011 21.5 0.1 5.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO25190.1 - 5.6e-08 32.1 7.9 0.08 12.9 0.1 6.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KDO25190.1 - 5.3e-06 26.2 1.2 0.048 13.5 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KDO25190.1 - 0.00015 21.6 4.3 1.1 9.2 0.1 4.3 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KDO25190.1 - 0.0023 18.1 0.0 0.53 10.5 0.0 2.9 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_5 PF13202.6 KDO25190.1 - 0.0098 15.3 4.9 0.15 11.6 0.1 4.0 3 0 0 3 3 3 1 EF hand DUF1380 PF07128.12 KDO25190.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) WD40 PF00400.32 KDO25191.1 - 3.2e-13 49.9 32.7 0.03 15.2 0.0 11.5 12 0 0 12 12 12 5 WD domain, G-beta repeat EF-hand_1 PF00036.32 KDO25191.1 - 9e-13 46.8 7.2 0.00045 19.6 0.2 3.9 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KDO25191.1 - 1.6e-09 38.0 2.8 0.00048 20.5 0.7 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO25191.1 - 2.9e-09 36.0 11.0 0.013 15.0 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO25191.1 - 3.6e-08 32.7 7.5 0.17 11.9 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KDO25191.1 - 1.8e-07 30.9 4.7 0.0087 15.9 0.6 3.4 3 0 0 3 3 3 2 EF-hand domain pair ANAPC4_WD40 PF12894.7 KDO25191.1 - 2e-05 24.8 0.2 0.29 11.5 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Calpain_inhib PF00748.19 KDO25191.1 - 0.0022 18.5 0.0 0.13 12.8 0.2 2.5 2 0 0 2 2 2 1 Calpain inhibitor DAGAT PF03982.13 KDO25193.1 - 2.6e-40 138.2 0.0 3.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ras PF00071.22 KDO25194.1 - 1.7e-16 60.2 0.0 2.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ras family EF_assoc_2 PF08356.12 KDO25194.1 - 2.3e-11 43.5 0.0 5.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 KDO25194.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF_assoc_1 PF08355.12 KDO25194.1 - 2.5e-06 27.0 0.0 1e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 EF hand associated EF-hand_1 PF00036.32 KDO25194.1 - 4.2e-06 25.9 0.1 1e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO25194.1 - 1.8e-05 25.1 0.3 7.4e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.27 KDO25194.1 - 2.6e-05 23.9 0.3 0.00087 18.9 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.6 KDO25194.1 - 3.8e-05 23.0 0.2 8.7e-05 21.8 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO25194.1 - 5.9e-05 22.7 0.1 0.00018 21.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain RsgA_GTPase PF03193.16 KDO25194.1 - 0.00014 21.9 0.4 0.21 11.5 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO25194.1 - 0.00051 20.1 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 KDO25194.1 - 0.005 16.7 0.3 0.018 14.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.23 KDO25194.1 - 0.011 15.8 0.3 0.024 14.7 0.3 1.5 1 1 0 1 1 1 0 Dynamin family Arf PF00025.21 KDO25194.1 - 0.016 14.6 0.0 0.046 13.2 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family Septin PF00735.18 KDO25194.1 - 0.026 13.8 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 KDO25194.1 - 0.045 12.9 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 KDO25194.1 - 0.11 12.4 0.1 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Peptidase_C13 PF01650.18 KDO25196.1 - 4.3e-44 150.9 0.1 5.5e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family PLATZ PF04640.14 KDO25197.1 - 0.12 13.0 8.1 0.17 12.5 8.1 1.5 1 1 0 1 1 1 0 PLATZ transcription factor Tubulin PF00091.25 KDO25198.1 - 1.5e-15 58.0 0.0 4.3e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain ASFV_J13L PF05568.11 KDO25198.1 - 0.046 13.5 2.6 0.075 12.8 2.6 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF1471 PF07338.13 KDO25198.1 - 0.15 12.1 0.4 0.79 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) UPF0029 PF01205.19 KDO25199.1 - 8e-29 100.1 0.0 1.4e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 EFG_C PF00679.24 KDO25199.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus ELO PF01151.18 KDO25200.1 - 3.2e-45 154.6 27.3 3.8e-45 154.4 27.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 KDO25200.1 - 3.5 7.9 5.0 25 5.1 0.2 2.6 2 0 0 2 2 2 0 CCSMST1 family CK_II_beta PF01214.18 KDO25201.1 - 4.6e-77 257.9 0.0 6.2e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NOA36 PF06524.12 KDO25201.1 - 0.15 11.4 8.6 0.28 10.5 8.6 1.3 1 0 0 1 1 1 0 NOA36 protein HscB_4_cys PF18256.1 KDO25201.1 - 0.37 10.7 4.4 1.5 8.7 0.2 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Nop14 PF04147.12 KDO25201.1 - 4.9 5.2 8.7 7.5 4.6 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KDO25201.1 - 7 4.6 12.3 9.8 4.1 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TMEM237 PF15383.6 KDO25202.1 - 0.05 12.7 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 FUN14 PF04930.15 KDO25202.1 - 0.087 13.3 1.2 2.6 8.5 1.7 2.6 3 0 0 3 3 3 0 FUN14 family PHD PF00628.29 KDO25203.1 - 1.8e-24 85.3 69.6 3.8e-09 36.3 9.1 6.6 5 1 2 7 7 7 5 PHD-finger FYRN PF05964.14 KDO25203.1 - 7.3e-16 57.8 0.1 1.7e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 KDO25203.1 - 7e-14 52.6 0.1 2.1e-13 51.0 0.1 1.9 1 0 0 1 1 1 1 SET domain Bromodomain PF00439.25 KDO25203.1 - 4.4e-11 42.7 0.0 9.8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain FYRC PF05965.14 KDO25203.1 - 4.4e-07 30.0 0.0 3.4e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 F/Y rich C-terminus TPR_MLP1_2 PF07926.12 KDO25205.1 - 0.027 14.5 0.5 0.47 10.5 0.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Glyco_hydro_18 PF00704.28 KDO25206.1 - 3.3e-21 76.4 0.3 3.3e-21 76.4 0.3 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 HA PF03457.14 KDO25207.1 - 3.5e-30 104.1 0.5 8.7e-11 42.0 0.7 4.1 4 0 0 4 4 4 3 Helicase associated domain Med26 PF08711.11 KDO25207.1 - 0.012 15.6 0.1 5.7 7.1 0.0 3.6 4 0 0 4 4 4 0 TFIIS helical bundle-like domain TFIIS_M PF07500.14 KDO25208.1 - 5.9e-11 42.8 0.0 8.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Exo84_C PF16528.5 KDO25208.1 - 0.065 13.0 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 Exocyst component 84 C-terminal Zn_Tnp_IS91 PF14319.6 KDO25208.1 - 0.31 11.1 2.5 0.44 10.6 0.4 1.9 1 1 1 2 2 2 0 Transposase zinc-binding domain EF-hand_4 PF12763.7 KDO25209.1 - 9.4e-09 35.2 0.0 0.0044 16.9 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Arm PF00514.23 KDO25210.1 - 4.6e-10 39.2 20.3 0.0004 20.3 0.4 5.1 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KDO25210.1 - 0.00049 19.5 0.5 0.00092 18.6 0.3 1.5 1 1 0 1 1 1 1 V-ATPase subunit H Tropomyosin_1 PF12718.7 KDO25210.1 - 0.22 11.7 5.5 0.36 11.0 5.5 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF4472 PF14739.6 KDO25210.1 - 0.46 11.2 4.3 0.81 10.4 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF3836 PF12930.7 KDO25211.1 - 0.046 13.5 0.2 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF3836) CTD_bind PF04818.13 KDO25211.1 - 0.062 14.1 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KDO25211.1 - 0.091 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Vault PF01505.18 KDO25212.1 - 1.6e-55 185.0 0.2 5.9e-15 55.1 0.0 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 KDO25212.1 - 2e-47 160.1 0.2 4.2e-47 159.0 0.2 1.6 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 KDO25212.1 - 2.1e-32 111.0 0.2 2.8e-27 94.5 0.0 4.0 3 1 1 4 4 4 3 Major Vault Protein Repeat domain Vault_2 PF17794.1 KDO25212.1 - 1.7e-31 108.3 0.2 3.6e-20 72.1 0.1 3.4 4 0 0 4 4 4 2 Major Vault Protein repeat domain Vault_4 PF17796.1 KDO25212.1 - 1.2e-25 89.3 0.0 1.7e-24 85.6 0.0 2.8 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 KDO25212.1 - 0.00019 21.4 0.1 9.1 6.5 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3601) PHD PF00628.29 KDO25213.1 - 6.8e-17 61.1 27.6 4.8e-09 36.0 9.5 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 KDO25213.1 - 1e-05 24.9 14.0 0.0025 17.3 1.1 3.0 3 0 0 3 3 3 2 PHD-finger NINJA_B PF16136.5 KDO25213.1 - 0.012 16.0 0.4 0.038 14.4 0.4 1.9 1 0 0 1 1 1 0 Putative nuclear localisation signal Cwf_Cwc_15 PF04889.12 KDO25213.1 - 0.13 11.9 16.2 0.91 9.2 9.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ank PF00023.30 KDO25214.1 - 9.5e-19 66.9 12.8 2.6e-05 24.5 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KDO25214.1 - 2.1e-17 61.4 6.2 0.041 14.4 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 KDO25214.1 - 2.2e-17 63.4 4.3 4.5e-07 30.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25214.1 - 2.9e-17 62.8 5.2 0.00021 21.8 0.0 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO25214.1 - 3.3e-16 59.1 8.5 2.7e-05 24.3 0.1 5.2 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Choline_transpo PF04515.12 KDO25215.1 - 3.8e-68 230.1 20.5 3.8e-68 230.1 20.5 2.1 2 1 0 2 2 2 1 Plasma-membrane choline transporter Erv26 PF04148.13 KDO25215.1 - 0.077 12.8 3.0 3.4 7.4 1.2 2.8 1 1 1 2 2 2 0 Transmembrane adaptor Erv26 Acyltransferase PF01553.21 KDO25216.1 - 5.6e-23 81.1 0.1 8.7e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Gaa1 PF04114.14 KDO25216.1 - 8.9 5.2 7.9 12 4.7 7.9 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component rve PF00665.26 KDO25217.1 - 3.3e-10 40.2 0.1 4.8e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain VD10_N PF08476.10 KDO25217.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Viral D10 N-terminal FXR_C3 PF16097.5 KDO25218.1 - 0.19 12.4 3.7 2.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 tRNA-synt_2 PF00152.20 KDO25219.1 - 2.4e-81 273.2 0.2 3.1e-81 272.9 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KDO25219.1 - 2.3e-11 43.5 0.0 5.8e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KDO25219.1 - 6.8e-06 25.7 0.1 0.0058 16.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF150_C PF17384.2 KDO25219.1 - 0.065 13.4 0.1 0.26 11.4 0.1 2.0 1 0 0 1 1 1 0 RimP C-terminal SH3 domain CRAL_TRIO PF00650.20 KDO25220.1 - 5.3e-15 55.5 0.0 8.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KDO25220.1 - 2.4e-08 34.6 0.1 0.00018 22.0 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking MDD_C PF18376.1 KDO25221.1 - 0.029 14.1 2.1 0.064 13.0 0.1 2.3 2 1 1 3 3 3 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain SCP1201-deam PF14428.6 KDO25221.1 - 0.033 14.1 0.2 0.081 12.8 0.0 1.8 1 1 1 2 2 2 0 SCP1.201-like deaminase NiFe-hyd_HybE PF11939.8 KDO25221.1 - 0.065 13.1 1.0 0.14 12.1 0.8 1.8 1 1 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE Hydrolase_4 PF12146.8 KDO25222.1 - 1.2e-11 44.4 0.0 2e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO25222.1 - 1.6e-09 37.8 0.0 1.5e-08 34.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO25222.1 - 2.3e-05 25.1 0.1 3.4e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 KDO25222.1 - 0.00023 20.2 0.0 0.00031 19.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KDO25222.1 - 0.004 16.9 0.0 0.0089 15.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KDO25222.1 - 0.0074 15.8 0.0 0.62 9.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KDO25222.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KDO25222.1 - 0.043 13.6 0.0 0.36 10.6 0.0 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase MRF_C2 PF13888.6 KDO25222.1 - 0.06 13.2 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 DLH PF01738.18 KDO25222.1 - 0.13 11.8 0.0 0.55 9.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF1749 PF08538.10 KDO25222.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) CobT PF06213.12 KDO25223.1 - 0.0053 16.2 2.9 0.0053 16.2 2.9 1.5 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DUF641 PF04859.12 KDO25223.1 - 0.019 15.3 0.8 0.051 13.9 0.1 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF2570 PF10828.8 KDO25223.1 - 0.076 12.8 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SlyX PF04102.12 KDO25223.1 - 0.084 13.5 0.6 0.24 12.0 0.6 1.8 1 0 0 1 1 1 0 SlyX Nop14 PF04147.12 KDO25223.1 - 1.4 7.1 7.9 2.1 6.4 7.9 1.3 1 0 0 1 1 1 0 Nop14-like family PGAP1 PF07819.13 KDO25225.1 - 3.2e-63 213.6 0.0 4.7e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KDO25225.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 KDO25225.1 - 0.0059 16.2 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KDO25225.1 - 0.035 13.4 0.0 0.086 12.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO25225.1 - 2.9 8.4 14.5 0.034 14.7 4.5 2.8 1 1 1 3 3 3 0 Alpha/beta hydrolase family LRR_8 PF13855.6 KDO25226.1 - 3.1e-45 151.7 34.4 1.1e-07 31.4 2.2 8.6 3 3 7 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KDO25226.1 - 1.6e-29 101.4 40.4 2.3e-05 24.7 3.2 10.6 4 2 8 13 13 13 8 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.6 KDO25226.1 - 1.4e-13 49.6 5.2 0.0014 18.4 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KDO25226.1 - 5.8e-13 47.4 3.2 0.0043 16.5 0.1 3.8 3 0 0 3 3 3 3 EF hand LRR_1 PF00560.33 KDO25226.1 - 2.1e-08 33.6 39.7 3.5 8.6 0.2 13.8 14 1 1 15 15 15 4 Leucine Rich Repeat EF-hand_7 PF13499.6 KDO25226.1 - 2.3e-08 34.4 0.6 2.4e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair LRR_9 PF14580.6 KDO25226.1 - 4.5e-07 29.5 6.8 0.28 10.7 0.1 4.3 3 1 1 4 4 4 3 Leucine-rich repeat EF-hand_5 PF13202.6 KDO25226.1 - 9.8e-05 21.7 4.3 0.41 10.2 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KDO25226.1 - 0.0009 19.0 0.2 1.8 8.5 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair LRR_6 PF13516.6 KDO25226.1 - 0.46 10.7 39.1 6.3 7.1 0.2 12.3 15 0 0 15 15 15 0 Leucine Rich repeat FYVE PF01363.21 KDO25227.1 - 1.9e-08 34.3 19.0 1.1e-07 31.8 19.0 2.2 1 1 0 1 1 1 1 FYVE zinc finger PDZ_6 PF17820.1 KDO25228.1 - 2.8e-16 59.1 0.0 1.9e-05 24.4 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KDO25228.1 - 2e-14 53.7 0.0 0.008 16.5 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KDO25228.1 - 0.0023 18.2 0.1 3.9 7.9 0.0 3.6 4 0 0 4 4 4 2 PDZ domain DUF4838 PF16126.5 KDO25228.1 - 0.014 14.8 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Tricorn_PDZ PF14685.6 KDO25228.1 - 0.037 14.0 0.0 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 Tricorn protease PDZ domain PDZ PF00595.24 KDO25229.1 - 2.1e-13 50.4 0.2 3.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KDO25229.1 - 3.1e-12 46.1 0.5 3.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO25229.1 - 0.0015 18.8 0.5 0.25 11.7 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KDO25230.1 - 1.1e-16 60.9 0.1 0.00014 22.1 0.0 3.6 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KDO25230.1 - 4.4e-09 36.1 0.0 0.088 12.7 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KDO25230.1 - 1.9e-05 24.9 3.3 1.1 9.7 0.2 3.8 3 1 0 3 3 3 3 PDZ domain DUF3318 PF11780.8 KDO25230.1 - 0.016 15.1 0.1 12 5.8 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3318) CK_II_beta PF01214.18 KDO25231.1 - 6.1e-68 228.2 0.0 7.3e-68 228.0 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 KDO25231.1 - 0.056 13.7 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sacchrp_dh_C PF16653.5 KDO25232.1 - 2.2e-69 234.5 0.0 2.7e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KDO25232.1 - 1e-07 32.3 0.7 1.6e-07 31.6 0.7 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GPP34 PF05719.11 KDO25232.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.4 2 1 1 3 3 3 0 Golgi phosphoprotein 3 (GPP34) NMT PF01233.19 KDO25233.1 - 8.7e-75 249.9 0.0 1.7e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 KDO25233.1 - 4.6e-73 245.2 0.0 7.8e-73 244.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 KDO25233.1 - 0.00095 19.2 0.3 0.0019 18.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO25233.1 - 0.037 14.3 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Cytadhesin_P30 PF07271.11 KDO25233.1 - 0.29 10.7 1.2 30 4.1 2.3 2.2 2 0 0 2 2 2 0 Cytadhesin P30/P32 Kinesin PF00225.23 KDO25234.1 - 1.8e-110 369.0 1.9 3.7e-110 368.0 1.9 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO25234.1 - 3.9e-46 156.7 0.1 8.8e-46 155.5 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding Atg14 PF10186.9 KDO25234.1 - 0.0019 17.3 5.7 0.0019 17.3 5.7 3.4 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Mt_ATP-synt_D PF05873.12 KDO25234.1 - 0.056 13.3 0.1 0.056 13.3 0.1 3.2 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Fer4_NifH PF00142.18 KDO25234.1 - 0.33 10.3 2.0 3 7.2 0.0 2.8 3 0 0 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1664 PF07889.12 KDO25234.1 - 2.8 8.0 11.3 0.15 12.1 2.8 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATPase_2 PF01637.18 KDO25234.1 - 3.8 7.3 7.0 4.5 7.1 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea STAG PF08514.11 KDO25235.1 - 9.1e-27 93.2 0.5 3.7e-26 91.3 0.5 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 KDO25235.1 - 0.00034 20.9 2.6 0.0053 17.1 0.2 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KDO25235.1 - 0.0012 18.9 7.2 0.11 12.8 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KDO25235.1 - 0.013 16.0 2.0 0.16 12.5 0.2 3.3 2 1 0 2 2 2 0 HEAT-like repeat Cnd1 PF12717.7 KDO25235.1 - 0.031 14.3 0.2 0.17 11.9 0.1 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ependymin PF00811.18 KDO25236.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Ependymin Cellulase PF00150.18 KDO25237.1 - 4.7e-13 49.2 0.0 1.8e-08 34.1 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Ribosomal_L34e PF01199.18 KDO25238.1 - 2.1e-40 136.9 8.1 3.1e-40 136.4 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Clat_adaptor_s PF01217.20 KDO25239.1 - 1.2e-50 171.1 0.2 1.3e-50 171.0 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 KDO25240.1 - 2.2e-15 56.2 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 KDO25241.1 - 1.4e-40 139.0 0.0 1.4e-21 77.5 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO25241.1 - 4.6e-16 59.5 0.8 1.4e-05 25.1 0.1 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO25241.1 - 7.9e-09 35.3 0.0 0.47 9.8 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO25241.1 - 1e-05 25.6 0.0 0.23 11.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO25241.1 - 1.2e-05 25.3 0.0 0.042 13.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 KDO25241.1 - 3e-05 24.0 0.3 0.27 11.1 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_29 PF13555.6 KDO25241.1 - 4.1e-05 23.2 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KDO25241.1 - 4.9e-05 23.6 0.0 0.46 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KDO25241.1 - 0.0001 21.6 0.1 0.051 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Roc PF08477.13 KDO25241.1 - 0.00016 21.9 0.0 0.69 10.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KDO25241.1 - 0.00021 20.6 0.1 0.058 12.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KDO25241.1 - 0.00025 21.6 0.7 0.082 13.5 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_22 PF13401.6 KDO25241.1 - 0.00026 21.3 0.1 0.71 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KDO25241.1 - 0.00028 21.5 0.0 0.75 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KDO25241.1 - 0.00045 20.4 0.3 0.03 14.4 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 KDO25241.1 - 0.00047 20.6 0.1 0.63 10.5 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KDO25241.1 - 0.00059 19.6 0.1 0.77 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KDO25241.1 - 0.00092 19.6 2.2 3.4 8.0 0.0 3.9 3 1 0 3 3 3 1 AAA ATPase domain ATP-synt_ab PF00006.25 KDO25241.1 - 0.00099 18.8 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KDO25241.1 - 0.0014 18.8 0.0 2 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO25241.1 - 0.0014 18.2 0.4 0.093 12.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KDO25241.1 - 0.0017 18.1 0.1 3.3 7.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain 4HB PF17947.1 KDO25241.1 - 0.0019 18.2 0.0 0.0049 16.9 0.0 1.7 1 0 0 1 1 1 1 Four helical bundle domain MeaB PF03308.16 KDO25241.1 - 0.0025 16.9 0.5 1.3 7.9 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KDO25241.1 - 0.003 17.9 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KDO25241.1 - 0.0037 16.8 0.0 2 7.9 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KDO25241.1 - 0.0037 17.0 0.0 0.95 9.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 KDO25241.1 - 0.0051 16.6 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 KDO25241.1 - 0.0082 16.0 0.1 6.6 6.4 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KDO25241.1 - 0.0095 16.3 0.3 0.88 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KDO25241.1 - 0.011 15.8 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KDO25241.1 - 0.016 15.1 0.5 4.2 7.3 0.1 2.7 3 0 0 3 3 2 0 NTPase TsaE PF02367.17 KDO25241.1 - 0.017 15.1 0.3 7.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KDO25241.1 - 0.032 14.2 0.1 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MukB PF04310.12 KDO25241.1 - 0.052 13.4 0.1 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Dynamin_N PF00350.23 KDO25241.1 - 0.075 13.1 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 1 0 Dynamin family AAA_17 PF13207.6 KDO25241.1 - 0.091 13.2 0.3 6.5 7.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KDO25241.1 - 0.1 12.2 0.4 17 5.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KDO25241.1 - 0.11 12.4 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KDO25241.1 - 0.11 12.3 0.4 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Septin PF00735.18 KDO25241.1 - 0.13 11.5 0.0 8.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin HEAT PF02985.22 KDO25241.1 - 0.16 12.3 3.7 26 5.4 0.0 4.6 4 0 0 4 4 3 0 HEAT repeat DUF3584 PF12128.8 KDO25241.1 - 0.42 8.1 2.6 2.1 5.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.6 KDO25241.1 - 0.61 10.6 9.6 7.5 7.2 0.0 5.0 5 0 0 5 5 4 0 HEAT-like repeat Methyltransf_10 PF05971.12 KDO25243.1 - 5.8e-79 265.5 0.0 1.6e-77 260.8 0.0 2.1 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KDO25243.1 - 5.4e-08 32.6 0.0 8.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KDO25243.1 - 5.4e-05 22.7 0.0 8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KDO25243.1 - 0.00031 20.7 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KDO25243.1 - 0.0022 17.7 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TrmK PF04816.12 KDO25243.1 - 0.0039 16.7 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_25 PF13649.6 KDO25243.1 - 0.011 16.5 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KDO25243.1 - 0.077 13.7 0.0 0.2 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KDO25243.1 - 0.094 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3648 PF12364.8 KDO25243.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) COX6C PF02937.15 KDO25245.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc p450 PF00067.22 KDO25246.1 - 2.6e-69 234.2 0.0 3.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SseB PF07179.12 KDO25247.1 - 0.00016 21.9 7.0 2.4 8.4 0.1 5.8 2 1 4 6 6 6 2 SseB protein N-terminal domain Lipase_2 PF01674.18 KDO25247.1 - 0.015 14.8 0.2 7.5 6.0 0.0 3.9 2 1 3 5 5 5 0 Lipase (class 2) Pkinase_Tyr PF07714.17 KDO25248.1 - 2.2e-12 46.9 0.0 5e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25248.1 - 1.6e-09 37.6 0.0 1.2e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 KDO25248.1 - 7.9e-07 28.7 1.7 0.0011 18.7 0.4 2.4 2 0 0 2 2 2 2 Leucine rich repeat STT3 PF02516.14 KDO25249.1 - 9.3e-99 331.6 29.3 1.3e-93 314.6 25.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Orai-1 PF07856.12 KDO25249.1 - 3.9 7.1 7.8 3 7.5 3.0 2.9 3 0 0 3 3 3 0 Mediator of CRAC channel activity Rubis-subs-bind PF09273.11 KDO25250.1 - 2.5e-06 28.2 0.1 4.1e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding NO_synthase PF02898.15 KDO25250.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain PAS_3 PF08447.12 KDO25251.1 - 1.2e-06 28.6 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 KDO25251.1 - 0.00032 20.8 1.6 0.00032 20.8 1.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KDO25251.1 - 0.00041 20.4 2.9 0.00093 19.2 2.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PAS PF00989.25 KDO25251.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_12 PF18095.1 KDO25251.1 - 0.018 14.7 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain PAS_4 PF08448.10 KDO25251.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 KDO25251.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain ROK PF00480.20 KDO25251.1 - 0.14 11.6 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 ROK family ATP12 PF07542.11 KDO25252.1 - 2.5e-34 118.2 0.1 3.6e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein AAA_16 PF13191.6 KDO25253.1 - 0.028 14.8 0.0 0.089 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Tubulin PF00091.25 KDO25255.1 - 1.2e-64 218.1 0.0 1.7e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO25255.1 - 5.3e-50 168.8 0.1 8.3e-50 168.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KDO25255.1 - 0.0045 16.7 0.0 0.015 15.0 0.0 1.9 3 0 0 3 3 3 1 Tubulin domain Ribosomal_L38e PF01781.18 KDO25256.1 - 5.8e-34 116.0 4.2 6.3e-34 115.9 4.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Pkinase_Tyr PF07714.17 KDO25257.1 - 7.5e-16 58.2 0.2 2.2e-15 56.6 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25257.1 - 2.7e-13 49.9 0.0 4.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KDO25257.1 - 3.9e-08 32.9 10.7 3.1e-05 23.6 1.2 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO25257.1 - 1.7e-06 28.2 1.4 1.7e-06 28.2 1.4 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Tubulin_C PF03953.17 KDO25258.1 - 5e-46 155.9 0.0 6.1e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain AAA_16 PF13191.6 KDO25259.1 - 0.091 13.1 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain cNMP_binding PF00027.29 KDO25260.1 - 1.2e-11 44.5 0.1 4.2e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Auxin_BP PF02041.16 KDO25260.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Trm112p PF03966.16 KDO25261.1 - 0.035 14.7 0.0 6.6 7.4 0.0 3.4 2 1 0 2 2 2 0 Trm112p-like protein Phage_TAC_11 PF11836.8 KDO25261.1 - 0.1 12.7 1.5 0.32 11.1 0.2 2.2 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 OTT_1508_deam PF14441.6 KDO25261.1 - 5 7.2 7.1 1.1 9.4 1.1 2.7 3 0 0 3 3 3 0 OTT_1508-like deaminase RMP PF14996.6 KDO25262.1 - 1.9e-39 135.4 14.4 8.1e-39 133.3 14.4 1.9 1 1 0 1 1 1 1 Retinal Maintenance FAM117 PF15388.6 KDO25262.1 - 0.038 13.4 7.0 0.048 13.1 7.0 1.3 1 0 0 1 1 1 0 Protein Family FAM117 UPF0220 PF05255.11 KDO25264.1 - 0.017 14.7 0.6 0.019 14.5 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) PLAC8 PF04749.17 KDO25264.1 - 0.02 15.9 0.0 0.024 15.6 0.0 1.2 1 0 0 1 1 1 0 PLAC8 family Phage_holin_3_6 PF07332.11 KDO25264.1 - 0.1 12.7 2.1 0.13 12.3 2.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Elicitin PF00964.17 KDO25265.1 - 1.5e-08 34.6 0.2 1.8e-08 34.4 0.2 1.1 1 0 0 1 1 1 1 Elicitin Adhesin_P1 PF03257.13 KDO25265.1 - 0.082 13.4 0.4 0.12 13.0 0.2 1.3 1 1 0 1 1 1 0 Mycoplasma adhesin P1 Sod_Cu PF00080.20 KDO25266.1 - 8.4e-37 126.5 1.7 1e-36 126.2 1.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HA PF03457.14 KDO25267.1 - 1.2e-16 60.8 0.1 4.7e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 Helicase associated domain Ribosomal_L30 PF00327.20 KDO25267.1 - 0.019 14.9 0.1 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e FAM183 PF14886.6 KDO25269.1 - 3.5e-06 27.7 0.1 4.6e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related NT-C2 PF10358.9 KDO25270.1 - 4.2e-07 29.8 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins LURAP PF14854.6 KDO25270.1 - 0.0057 16.6 0.5 0.052 13.5 0.1 2.6 2 0 0 2 2 2 1 Leucine rich adaptor protein Med4 PF10018.9 KDO25270.1 - 0.031 14.0 5.8 0.052 13.2 0.7 2.5 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RcbX PF02341.15 KDO25270.1 - 0.089 13.1 0.3 0.089 13.1 0.3 2.7 3 0 0 3 3 3 0 RbcX protein DUF2612 PF11041.8 KDO25270.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) DUF4140 PF13600.6 KDO25270.1 - 0.32 11.4 11.9 7.6 7.1 0.2 5.5 6 1 0 6 6 6 0 N-terminal domain of unknown function (DUF4140) EzrA PF06160.12 KDO25270.1 - 0.37 8.9 11.3 0.47 8.6 2.6 3.1 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 KDO25270.1 - 0.51 10.4 12.1 0.5 10.4 5.7 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 KDO25270.1 - 0.72 9.9 22.0 0.35 11.0 4.3 3.8 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KDO25270.1 - 2.5 8.6 11.8 3.5 8.2 0.4 3.7 3 1 0 3 3 3 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KDO25270.1 - 2.9 8.1 17.9 5 7.3 4.7 3.9 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KDO25270.1 - 3.4 7.7 10.7 27 4.8 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3138 PF11336.8 KDO25270.1 - 4.6 5.7 6.4 9 4.8 2.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) DASH_Dam1 PF08653.10 KDO25270.1 - 6.6 6.6 6.2 12 5.8 0.1 4.3 4 0 0 4 4 3 0 DASH complex subunit Dam1 TMCO5 PF14992.6 KDO25270.1 - 9.2 5.7 16.3 48 3.4 9.4 3.5 2 1 1 3 3 3 0 TMCO5 family Peptidase_C14 PF00656.22 KDO25271.1 - 1.3e-53 182.6 0.0 1.7e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Nup35_RRM PF05172.13 KDO25271.1 - 0.0061 16.5 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Ldh_1_C PF02866.18 KDO25272.1 - 2.6e-26 92.5 0.1 3.9e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KDO25272.1 - 3.9e-25 88.6 0.1 6.3e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Pkinase PF00069.25 KDO25273.1 - 7.2e-15 55.1 0.0 9.5e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25273.1 - 3.7e-10 39.5 0.0 4.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase McyA_C PF12593.8 KDO25273.1 - 0.052 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Microcystin synthetase C terminal Pkinase PF00069.25 KDO25274.1 - 5.7e-44 150.5 0.0 2.8e-43 148.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25274.1 - 6.5e-22 78.1 0.0 4.1e-21 75.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25274.1 - 1.3e-05 24.6 0.0 4.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH_6_hur PF04655.14 KDO25274.1 - 0.0042 16.5 0.5 0.19 11.1 0.0 2.1 1 1 1 2 2 2 2 Aminoglycoside/hydroxyurea antibiotic resistance kinase RWP-RK PF02042.15 KDO25275.1 - 1.2e-08 34.8 0.1 2.3e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HEAT PF02985.22 KDO25276.1 - 3.3e-17 61.1 12.7 6.7e-07 29.0 0.0 8.1 9 0 0 9 9 8 3 HEAT repeat HEAT_EZ PF13513.6 KDO25276.1 - 1.7e-12 47.5 28.9 4.8e-09 36.5 0.0 9.1 9 2 1 10 10 10 3 HEAT-like repeat Importin_rep_4 PF18808.1 KDO25276.1 - 4.6e-12 46.0 0.1 4.6e-12 46.0 0.1 4.0 5 0 0 5 5 4 1 Importin repeat HEAT_2 PF13646.6 KDO25276.1 - 7.9e-12 45.4 11.3 4e-08 33.5 0.2 6.9 4 3 3 7 7 7 1 HEAT repeats Tti2 PF10521.9 KDO25276.1 - 0.00022 20.9 0.0 0.26 10.8 0.0 3.2 2 1 0 2 2 2 2 Tti2 family MMS19_C PF12460.8 KDO25276.1 - 0.00056 19.1 2.8 0.029 13.5 0.0 4.3 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.16 KDO25276.1 - 0.011 16.3 6.4 2.3 9.2 0.0 5.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KDO25276.1 - 0.019 15.5 0.0 1.5 9.5 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 KDO25276.1 - 0.077 13.3 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion RICTOR_V PF14668.6 KDO25276.1 - 0.11 12.7 0.0 7.2 6.9 0.0 3.0 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Dopey_N PF04118.14 KDO25276.1 - 0.62 9.1 5.4 39 3.2 0.0 4.8 6 0 0 6 6 6 0 Dopey, N-terminal Sec7_N PF12783.7 KDO25276.1 - 2.8 7.8 6.8 6.3 6.7 0.3 3.4 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal VPS13 PF16908.5 KDO25277.1 - 7.8e-26 91.3 0.0 3.1e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KDO25277.1 - 3.7e-21 75.4 0.2 1.1e-20 73.8 0.2 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 C2 PF00168.30 KDO25277.1 - 0.0013 19.0 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain VPS13 PF16908.5 KDO25278.1 - 1.4e-23 83.9 0.0 2.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KDO25278.1 - 7e-15 55.2 0.3 5.1e-14 52.4 0.0 2.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 CCT PF06203.14 KDO25279.1 - 6.1e-18 64.6 9.3 9.2e-18 64.0 9.3 1.3 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 KDO25279.1 - 0.38 10.7 4.3 0.94 9.4 4.3 1.6 1 0 0 1 1 1 0 Divergent CCT motif p450 PF00067.22 KDO25280.1 - 7.2e-21 74.5 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 KDO25280.1 - 2.6e-15 55.9 0.2 5.8e-15 54.8 0.2 1.5 1 1 0 1 1 1 1 Lipoxygenase Lipoxygenase PF00305.19 KDO25281.1 - 7.4e-10 37.9 2.8 4.6e-09 35.3 2.8 1.9 1 1 0 1 1 1 1 Lipoxygenase p450 PF00067.22 KDO25281.1 - 4e-09 35.7 0.0 9.8e-09 34.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 KDO25282.1 - 0.18 10.2 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase V_ATPase_I PF01496.19 KDO25283.1 - 1e-101 341.3 7.7 1.8e-52 178.4 4.6 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family HWE_HK PF07536.14 KDO25283.1 - 0.27 12.0 2.7 18 6.1 0.3 3.1 2 1 1 3 3 3 0 HWE histidine kinase p450 PF00067.22 KDO25284.1 - 3.4e-21 75.5 0.0 5.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 KDO25284.1 - 1.1e-11 44.0 0.1 3e-11 42.5 0.1 1.6 1 1 0 1 1 1 1 Lipoxygenase Y_phosphatase3 PF13350.6 KDO25284.1 - 0.095 12.6 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family p450 PF00067.22 KDO25287.1 - 4.8e-16 58.6 0.0 8.3e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 KDO25287.1 - 2.5e-13 49.4 0.3 8e-13 47.7 0.3 1.7 1 1 0 1 1 1 1 Lipoxygenase p450 PF00067.22 KDO25288.1 - 2.4e-18 66.1 0.0 4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 KDO25288.1 - 7.4e-16 57.7 0.2 1.8e-15 56.4 0.2 1.5 1 1 0 1 1 1 1 Lipoxygenase Ank_4 PF13637.6 KDO25289.1 - 5.6e-17 61.9 0.0 1.5e-07 31.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO25289.1 - 1.8e-16 60.5 0.1 8.3e-14 52.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO25289.1 - 3.4e-15 55.9 0.4 1e-07 32.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO25289.1 - 4.3e-14 52.2 0.1 0.00013 22.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO25289.1 - 1.4e-09 37.4 0.0 0.0019 18.5 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeat Pkinase PF00069.25 KDO25290.1 - 2.8e-39 135.1 0.0 1.6e-37 129.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25290.1 - 8.2e-38 130.2 0.0 6e-37 127.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO25290.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO25290.1 - 0.025 14.5 1.1 0.052 13.5 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Orthoreo_P10 PF07204.11 KDO25290.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Haspin_kinase PF12330.8 KDO25290.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KDO25291.1 - 2.6e-47 161.3 0.0 4.2e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25291.1 - 2.8e-47 161.3 0.0 2.4e-46 158.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO25291.1 - 1.2e-07 30.9 0.1 1.4e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO25291.1 - 0.0039 16.5 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO25291.1 - 0.017 15.0 0.3 0.049 13.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO25291.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2759 PF10958.8 KDO25291.1 - 0.19 11.5 2.1 4.4 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) Pkinase PF00069.25 KDO25293.1 - 3e-35 121.9 0.0 3.7e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25293.1 - 3.4e-31 108.5 0.0 4.1e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO25293.1 - 0.00095 18.0 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO25293.1 - 0.037 13.9 0.0 0.074 13.0 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO25294.1 - 2e-46 158.5 0.0 3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25294.1 - 2.8e-42 144.8 0.0 4.1e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO25294.1 - 0.045 12.5 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO25294.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO25295.1 - 2.2e-45 155.1 0.0 3.1e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25295.1 - 4.5e-41 140.9 0.0 6.6e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 KDO25295.1 - 0.0016 17.8 1.5 0.003 16.9 1.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 KDO25295.1 - 0.054 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO25295.1 - 0.19 11.6 0.0 0.64 9.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO25296.1 - 2.2e-46 158.4 0.0 3.4e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25296.1 - 1.4e-41 142.5 0.0 1.8e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 KDO25296.1 - 0.0015 17.9 1.5 0.0015 17.9 1.5 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 KDO25296.1 - 0.0061 15.4 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EphA2_TM PF14575.6 KDO25296.1 - 0.017 16.0 0.1 0.062 14.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KDO25296.1 - 0.026 14.3 0.3 0.054 13.3 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1970 PF09301.10 KDO25296.1 - 0.034 14.4 0.5 9.2 6.6 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) APH PF01636.23 KDO25296.1 - 0.049 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMEM51 PF15345.6 KDO25296.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Haspin_kinase PF12330.8 KDO25296.1 - 0.13 11.2 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Protocadherin PF08374.11 KDO25296.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Protocadherin Syndecan PF01034.20 KDO25296.1 - 0.21 11.5 0.4 0.52 10.3 0.4 1.6 1 0 0 1 1 1 0 Syndecan domain zf-MYND PF01753.18 KDO25296.1 - 1.9 8.6 5.5 15 5.8 1.8 2.7 2 1 0 2 2 2 0 MYND finger Alginate_lyase PF05426.12 KDO25297.1 - 3.9e-10 39.7 0.5 1e-09 38.4 0.5 1.6 1 0 0 1 1 1 1 Alginate lyase PH PF00169.29 KDO25298.1 - 1.1e-16 61.3 0.0 3e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 PH domain VPS9 PF02204.18 KDO25298.1 - 1.2e-15 57.6 0.1 2e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH_11 PF15413.6 KDO25298.1 - 2.7e-06 27.7 0.2 1.2e-05 25.6 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO25298.1 - 7e-06 26.2 0.0 2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pex24p PF06398.11 KDO25298.1 - 3.5e-05 23.0 1.9 5.3e-05 22.4 1.9 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin AveC_like PF17198.4 KDO25299.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Spirocyclase AveC-like Ssl1 PF04056.14 KDO25300.1 - 2e-70 236.6 0.0 2.5e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KDO25300.1 - 1e-13 51.8 0.0 5.3e-13 49.5 0.0 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain C1_4 PF07975.12 KDO25300.1 - 3.4e-11 43.2 15.4 3.4e-11 43.2 15.4 3.0 2 1 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.28 KDO25300.1 - 5.5e-06 26.7 0.0 7.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KDO25300.1 - 0.00042 19.9 0.3 0.00042 19.9 0.3 2.3 2 0 0 2 2 2 1 Transcription factor Tfb4 IBR PF01485.21 KDO25300.1 - 0.018 15.3 4.3 0.018 15.3 4.3 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 KDO25300.1 - 4.4 7.2 17.3 7.1 6.5 0.8 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Nop25 PF09805.9 KDO25301.1 - 3.4e-12 47.0 16.9 3.4e-12 47.0 16.9 2.3 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) PhosphMutase PF10143.9 KDO25301.1 - 0.078 12.8 1.1 0.14 12.0 0.4 1.7 1 1 1 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase zf-HC2 PF13490.6 KDO25301.1 - 0.11 12.8 1.7 0.19 12.0 1.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger DUF2508 PF10704.9 KDO25301.1 - 0.49 10.6 9.5 1.5 9.0 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) YqzH PF14164.6 KDO25301.1 - 1.1 9.3 5.4 1.3 9.1 1.5 2.7 2 1 1 3 3 3 0 YqzH-like protein Band_3_cyto PF07565.13 KDO25301.1 - 7.3 6.3 9.7 0.87 9.3 2.5 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF5383 PF17355.2 KDO25301.1 - 9.5 6.6 11.3 14 6.1 3.8 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5383) Peptidase_M17 PF00883.21 KDO25302.1 - 1.3e-92 310.4 3.5 1.8e-92 310.0 3.5 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KDO25302.1 - 2.2e-23 82.8 0.5 2.2e-23 82.8 0.5 2.2 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 DUF2013 PF09431.10 KDO25303.1 - 5.5e-06 26.6 0.0 7.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF3437 PF11919.8 KDO25304.1 - 0.077 12.9 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) SAM_decarbox PF01536.16 KDO25305.1 - 6.7e-101 337.8 0.0 7.6e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Fringe PF02434.16 KDO25306.1 - 4.9e-12 45.8 0.0 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KDO25306.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.5 1 1 0 1 1 1 0 Galactosyltransferase RCC1 PF00415.18 KDO25307.1 - 5.1e-28 97.5 3.3 5.3e-13 49.4 0.0 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO25307.1 - 3e-21 74.7 14.1 1.1e-09 37.9 1.2 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat VPS13_C PF16909.5 KDO25308.1 - 1.6e-19 70.4 4.7 5.4e-19 68.6 0.0 3.1 2 1 1 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KDO25308.1 - 4.9e-18 65.3 0.0 1.1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KDO25308.1 - 2.4e-07 31.0 0.4 1.6e-05 25.1 0.1 3.5 2 1 1 3 3 3 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 KDO25308.1 - 3.7e-07 30.2 0.0 7.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal tRNA-synt_1g PF09334.11 KDO25310.1 - 3.3e-102 342.2 2.8 3.6e-56 190.6 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KDO25310.1 - 2.7e-36 125.0 5.0 3.7e-24 84.9 0.3 3.1 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 KDO25310.1 - 4.6e-24 84.3 0.0 8.5e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 KDO25310.1 - 1.8e-14 53.8 0.3 9.5e-08 31.7 0.4 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KDO25310.1 - 2.1e-07 30.2 0.1 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 KDO25310.1 - 3e-06 27.3 0.2 7e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA WD40 PF00400.32 KDO25311.1 - 3.7e-14 52.9 21.6 0.28 12.1 0.3 9.4 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25311.1 - 3.1e-09 37.0 1.5 0.1 12.9 0.0 5.7 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 KDO25311.1 - 0.0001 21.6 0.3 0.00027 20.3 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KDO25311.1 - 0.00012 21.9 0.1 0.00033 20.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO25311.1 - 0.00013 22.3 0.1 0.00031 21.1 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO25311.1 - 0.00032 20.0 1.5 0.00057 19.2 0.5 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO25311.1 - 0.0022 17.8 0.2 0.0081 16.0 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain Ge1_WD40 PF16529.5 KDO25311.1 - 0.02 13.9 0.0 7.2 5.5 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein His_Phos_1 PF00300.22 KDO25311.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) PHM7_cyt PF14703.6 KDO25312.1 - 1.5e-08 35.0 0.1 5.1e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 KDO25312.1 - 1.4e-06 27.9 5.4 1.4e-06 27.9 5.4 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RRM_1 PF00076.22 KDO25312.1 - 0.0016 18.2 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lebercilin PF15619.6 KDO25312.1 - 0.0051 16.5 1.2 0.01 15.5 1.2 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF4279 PF14106.6 KDO25312.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DegS PF05384.11 KDO25315.1 - 0.0093 15.5 4.2 0.017 14.6 4.2 1.4 1 0 0 1 1 1 1 Sensor protein DegS pEK499_p136 PF18736.1 KDO25315.1 - 0.033 13.8 1.1 0.074 12.7 0.3 1.8 2 0 0 2 2 2 0 HEPN pEK499 p136 Lipase_3 PF01764.25 KDO25316.1 - 5.6e-27 94.4 0.0 1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KDO25316.1 - 0.00062 19.4 0.1 0.005 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KDO25316.1 - 0.0024 18.5 0.0 0.012 16.3 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO25316.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold WGR PF05406.15 KDO25317.1 - 8.2e-21 73.9 0.0 1.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 WGR domain WWE PF02825.20 KDO25317.1 - 3.1e-08 34.1 2.1 6.8e-08 33.0 2.1 1.6 1 0 0 1 1 1 1 WWE domain Topo_Zn_Ribbon PF08272.11 KDO25317.1 - 0.14 11.9 0.2 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like BUD22 PF09073.10 KDO25318.1 - 0.013 14.8 8.4 0.017 14.5 8.4 1.3 1 0 0 1 1 1 0 BUD22 Exo84_C PF16528.5 KDO25318.1 - 0.07 12.9 1.7 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Exocyst component 84 C-terminal NAM-associated PF14303.6 KDO25318.1 - 2 9.1 5.3 1 10.1 2.7 1.8 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Acyl-CoA_dh_2 PF08028.11 KDO25318.1 - 2.1 8.6 11.4 0.29 11.4 1.2 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ADP_ribosyl_GH PF03747.14 KDO25319.1 - 0.0042 16.9 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF4200 PF13863.6 KDO25320.1 - 0.00035 20.9 4.1 0.00035 20.9 4.1 8.2 3 2 4 7 7 7 1 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KDO25320.1 - 0.0068 16.5 17.7 0.0068 16.5 17.7 8.5 4 3 3 8 8 8 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 KDO25320.1 - 0.0096 15.9 1.8 0.0096 15.9 1.8 9.7 9 3 1 10 10 10 3 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KDO25320.1 - 0.017 15.3 1.4 0.017 15.3 1.4 8.8 1 1 7 9 9 9 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 KDO25320.1 - 0.018 15.2 34.1 0.089 13.0 0.1 9.6 9 0 0 9 9 9 0 Homeobox associated leucine zipper Spc7 PF08317.11 KDO25320.1 - 0.52 9.1 85.8 0.073 11.9 6.2 6.1 1 1 4 6 6 6 0 Spc7 kinetochore protein GAS PF13851.6 KDO25320.1 - 0.93 8.8 75.4 0.014 14.7 11.4 6.6 1 1 5 7 7 7 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KDO25320.1 - 7.6 6.0 84.3 0.59 9.7 7.2 7.0 1 1 6 7 7 7 0 Intermediate filament protein Methyltransf_25 PF13649.6 KDO25321.1 - 5.6e-07 30.2 0.1 3.2e-05 24.5 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KDO25321.1 - 1.3e-06 28.1 0.5 2.6e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO25321.1 - 3.2e-06 27.7 0.0 0.0023 18.6 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KDO25321.1 - 0.00041 20.2 0.0 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KDO25321.1 - 0.013 15.4 0.2 0.078 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KDO25321.1 - 0.059 12.9 0.3 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain KorB_C PF06613.11 KDO25321.1 - 0.11 12.5 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Methyltransf_31 PF13847.6 KDO25321.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_ab PF00006.25 KDO25322.1 - 4.7e-31 108.1 0.0 7.6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 KDO25322.1 - 0.0023 18.4 0.0 0.0086 16.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab_N PF02874.23 KDO25322.1 - 0.0025 18.3 0.1 0.0074 16.8 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KDO25322.1 - 0.026 14.9 0.0 0.089 13.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KDO25322.1 - 0.093 13.1 0.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KDO25322.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KDO25322.1 - 0.19 11.8 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PARP PF00644.20 KDO25323.1 - 1.4e-41 142.2 0.0 1.9e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KDO25323.1 - 2.2e-31 108.8 0.0 4.1e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KDO25323.1 - 1.8e-17 63.2 0.3 4e-17 62.1 0.3 1.6 1 0 0 1 1 1 1 WGR domain DUF5338 PF17273.2 KDO25325.1 - 0.058 13.5 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5338) DUF5338 PF17273.2 KDO25326.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) CENP-M PF11111.8 KDO25327.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) SR-25 PF10500.9 KDO25327.1 - 2.5 7.6 7.9 3.5 7.2 7.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sigma70_ECF PF07638.11 KDO25328.1 - 0.062 13.2 0.1 0.071 13.0 0.1 1.1 1 0 0 1 1 1 0 ECF sigma factor WD40 PF00400.32 KDO25331.1 - 6.6e-62 204.0 17.3 7.9e-09 36.0 0.9 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25331.1 - 3.3e-14 52.9 0.0 0.11 12.8 0.0 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO25331.1 - 1.1e-08 34.5 0.4 0.13 11.2 0.1 5.1 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO25331.1 - 0.006 15.3 0.7 15 4.1 0.0 3.9 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KDO25331.1 - 0.011 15.1 0.4 0.44 9.8 0.1 2.5 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KDO25331.1 - 0.015 13.6 0.0 0.057 11.7 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KDO25331.1 - 0.04 13.9 0.1 10 6.2 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PH PF00169.29 KDO25332.1 - 3.8e-08 33.8 0.0 6.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO25332.1 - 0.00012 22.4 0.2 0.01 16.2 0.2 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KDO25332.1 - 0.00021 21.5 0.1 0.00039 20.6 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain CAP_N PF01213.19 KDO25332.1 - 0.29 10.6 1.9 0.41 10.1 1.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1925 PF09094.11 KDO25333.1 - 0.24 11.7 0.9 19 5.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) GlcNAc PF11397.8 KDO25336.1 - 4.8e-44 151.2 0.0 2.3e-36 126.0 0.0 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Myb_DNA-bind_3 PF12776.7 KDO25337.1 - 2.3e-06 28.5 3.6 0.011 16.7 0.5 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO25337.1 - 8.1e-05 22.9 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 KDO25337.1 - 0.0035 17.9 0.1 3.8 8.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF573 MADF_DNA_bdg PF10545.9 KDO25337.1 - 0.019 15.3 0.1 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TEA PF01285.18 KDO25337.1 - 0.051 13.7 0.1 6.7 6.9 0.0 3.1 3 0 0 3 3 3 0 TEA/ATTS domain PDZ_6 PF17820.1 KDO25338.1 - 6.3e-19 67.6 0.2 2.8e-06 27.1 0.1 4.3 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 KDO25338.1 - 1e-15 57.8 0.0 0.021 15.2 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KDO25338.1 - 2.2e-08 34.3 1.2 0.012 16.0 0.0 4.2 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 KDO25338.1 - 0.00041 20.2 0.0 2.6 8.0 0.0 3.9 4 0 0 4 4 4 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 KDO25338.1 - 0.041 14.3 0.0 38 4.7 0.0 3.2 3 0 0 3 3 3 0 PDZ domain Peptidase_C48 PF02902.19 KDO25339.1 - 2.3e-06 27.6 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GAS PF13851.6 KDO25339.1 - 0.01 15.2 0.6 0.018 14.4 0.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPD52 PF04201.15 KDO25339.1 - 0.021 14.4 0.3 0.034 13.7 0.3 1.3 1 0 0 1 1 1 0 Tumour protein D52 family FUSC PF04632.12 KDO25339.1 - 0.023 13.3 6.8 0.04 12.4 6.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 KDO25339.1 - 0.025 15.1 2.7 0.051 14.1 2.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Cnn_1N PF07989.11 KDO25339.1 - 0.13 12.4 1.6 0.44 10.7 0.4 2.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KDO25339.1 - 0.2 12.1 2.9 0.27 11.7 0.4 2.1 2 0 0 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 KDO25339.1 - 0.52 10.6 3.1 9.1 6.6 0.2 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper HalX PF08663.10 KDO25339.1 - 2.8 8.3 9.7 36 4.8 1.5 2.5 1 1 1 2 2 2 0 HalX domain COesterase PF00135.28 KDO25340.1 - 1.1e-14 54.3 2.1 2.2e-14 53.2 2.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KDO25340.1 - 6.3e-11 42.5 0.4 8.5e-11 42.1 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KDO25340.1 - 2.2e-07 30.1 0.1 3.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KDO25340.1 - 0.00015 21.1 1.1 0.0015 17.9 1.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO25340.1 - 0.00016 22.4 0.7 0.00016 22.4 0.7 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO25340.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KDO25340.1 - 0.15 11.6 0.6 1.4 8.5 0.1 2.4 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Pkinase PF00069.25 KDO25341.1 - 5.4e-61 206.3 0.0 6.2e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25341.1 - 6.9e-31 107.5 0.0 8.1e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25341.1 - 5.5e-07 29.2 0.0 2.9e-06 26.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KDO25341.1 - 8.4e-05 21.7 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO25341.1 - 0.00026 21.0 0.0 0.00048 20.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO25341.1 - 0.09 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO25343.1 - 2.4e-29 102.4 0.0 1.4e-27 96.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25343.1 - 5.6e-23 81.6 0.0 5e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Sec1 PF00995.23 KDO25344.1 - 1.3e-53 183.2 0.0 2.1e-53 182.4 0.0 1.3 1 1 0 1 1 1 1 Sec1 family Glyco_hydro_31 PF01055.26 KDO25346.1 - 1.2e-137 459.7 5.5 1.6e-137 459.3 5.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KDO25346.1 - 2.4e-30 105.1 0.0 8.7e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KDO25346.1 - 1.9e-10 40.4 19.0 1.5e-06 28.0 4.0 3.2 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KDO25346.1 - 1.5e-08 34.8 0.3 4e-08 33.5 0.3 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like ssDNA-exonuc_C PF10141.9 KDO25347.1 - 0.013 15.1 0.1 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain RNA_POL_M_15KD PF02150.16 KDO25348.1 - 2.4e-11 43.3 3.9 2.4e-11 43.3 3.9 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-RRN7 PF11781.8 KDO25348.1 - 0.0034 17.0 6.5 3.2 7.5 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 KDO25348.1 - 0.006 16.6 6.1 0.37 10.8 6.2 2.3 1 1 0 1 1 1 1 Double zinc ribbon Ogr_Delta PF04606.12 KDO25348.1 - 0.0077 16.2 0.3 3.3 7.8 0.1 2.5 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zinc_ribbon_9 PF14369.6 KDO25348.1 - 0.008 16.4 4.1 0.52 10.6 0.1 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-ribbon_3 PF13248.6 KDO25348.1 - 0.012 15.0 7.0 1.5 8.4 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.18 KDO25348.1 - 0.014 15.2 5.5 3.1 7.7 0.0 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-LITAF-like PF10601.9 KDO25348.1 - 0.038 14.3 5.4 0.41 10.9 0.0 2.9 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KDO25348.1 - 0.059 13.5 7.8 1.7 8.8 0.0 3.1 2 1 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 KDO25348.1 - 0.064 13.3 3.4 0.069 13.2 0.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KDO25348.1 - 0.066 13.0 8.8 3.1 7.7 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KDO25348.1 - 0.069 12.9 8.9 1.1 9.1 0.1 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain MCM_OB PF17207.3 KDO25348.1 - 0.12 12.2 1.1 0.14 12.0 0.3 1.7 1 1 0 1 1 1 0 MCM OB domain DnaJ_CXXCXGXG PF00684.19 KDO25348.1 - 0.21 12.0 5.8 0.66 10.4 0.1 2.5 2 1 0 2 2 2 0 DnaJ central domain Zn_ribbon_recom PF13408.6 KDO25348.1 - 0.23 12.0 4.0 1.2 9.7 0.8 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_10 PF10058.9 KDO25348.1 - 0.23 11.2 8.0 0.074 12.8 2.0 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 KDO25348.1 - 0.26 11.3 4.2 1.4 8.9 1.9 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KDO25348.1 - 0.27 11.2 9.5 0.79 9.8 0.2 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 KDO25348.1 - 0.28 10.8 6.3 10 5.8 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 KDO25348.1 - 0.32 11.0 4.3 1.8 8.6 2.0 2.4 2 0 0 2 2 2 0 zinc-ribbons CpXC PF14353.6 KDO25348.1 - 0.36 10.9 6.0 0.51 10.4 0.4 2.4 1 1 1 2 2 2 0 CpXC protein zf-ACC PF17848.1 KDO25348.1 - 0.39 10.8 11.0 2.5 8.2 2.7 3.8 3 1 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DNA_RNApol_7kD PF03604.13 KDO25348.1 - 0.66 9.7 5.6 7.2 6.4 0.2 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Lar_restr_allev PF14354.6 KDO25348.1 - 0.69 10.3 6.6 3 8.3 0.1 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 KDO25348.1 - 1.3 8.6 11.6 1.3 8.6 2.9 3.0 3 1 0 3 3 2 0 TFIIB zinc-binding zf-RING_7 PF02591.15 KDO25348.1 - 1.6 9.0 5.7 8 6.7 0.9 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain Zn_Tnp_IS91 PF14319.6 KDO25348.1 - 1.9 8.6 7.7 2.9 8.0 2.7 2.9 2 1 1 3 3 3 0 Transposase zinc-binding domain zf-IS66 PF13005.7 KDO25348.1 - 5.8 7.4 9.1 17 5.9 0.2 3.3 2 1 2 4 4 4 0 zinc-finger binding domain of transposase IS66 Rubredoxin_2 PF18073.1 KDO25348.1 - 9.8 6.0 11.6 5.3 6.9 0.7 3.8 4 0 0 4 4 4 0 Rubredoxin metal binding domain KdpD PF02702.17 KDO25350.1 - 0.028 13.9 0.3 0.033 13.7 0.3 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain bZIP_1 PF00170.21 KDO25350.1 - 0.05 13.7 7.7 1.5 9.0 5.8 2.1 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KDO25350.1 - 0.076 13.1 0.2 0.076 13.1 0.2 2.6 2 1 0 2 2 2 0 Basic region leucine zipper RIBIOP_C PF04950.12 KDO25350.1 - 0.18 11.2 0.4 0.21 11.0 0.4 1.0 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PET117 PF15786.5 KDO25350.1 - 4.4 7.6 10.2 1.7 9.0 6.2 2.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial YukD PF08817.10 KDO25352.1 - 0.043 14.5 0.0 0.075 13.7 0.0 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD CSRNP_N PF16019.5 KDO25353.1 - 9.5e-10 38.8 0.7 1.9e-09 37.8 0.7 1.6 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus HA PF03457.14 KDO25353.1 - 0.029 14.7 0.2 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain ABC_membrane PF00664.23 KDO25354.1 - 2.2e-98 329.3 24.3 7.9e-51 173.3 4.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO25354.1 - 1.7e-70 235.8 0.0 1.6e-34 119.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO25354.1 - 3.3e-11 43.0 3.4 0.00025 20.6 0.0 3.8 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO25354.1 - 2.1e-06 28.2 5.8 0.0049 17.3 0.2 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO25354.1 - 3.6e-06 26.6 3.2 0.032 14.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO25354.1 - 5.4e-06 26.7 0.9 0.13 12.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KDO25354.1 - 8.1e-06 25.2 0.1 0.052 12.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.17 KDO25354.1 - 2.1e-05 24.7 0.7 0.032 14.3 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 KDO25354.1 - 6.1e-05 22.9 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 KDO25354.1 - 0.00016 21.0 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit ABC_ATPase PF09818.9 KDO25354.1 - 0.00036 19.5 4.2 0.041 12.7 0.2 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_28 PF13521.6 KDO25354.1 - 0.00052 20.3 0.1 0.49 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KDO25354.1 - 0.0011 18.9 2.6 2 8.2 0.0 3.6 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KDO25354.1 - 0.0013 18.5 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO25354.1 - 0.0014 18.5 2.5 1.2 9.0 0.1 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_18 PF13238.6 KDO25354.1 - 0.0015 19.1 0.0 0.25 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO25354.1 - 0.003 17.3 3.3 1.5 8.5 0.6 3.6 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KDO25354.1 - 0.0042 17.3 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KDO25354.1 - 0.0054 17.0 5.0 3.2 8.1 0.2 4.5 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KDO25354.1 - 0.0071 15.9 3.3 0.35 10.4 0.0 3.4 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.20 KDO25354.1 - 0.0076 16.2 0.1 5.5 6.9 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_7 PF12775.7 KDO25354.1 - 0.0097 15.4 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KDO25354.1 - 0.017 14.5 0.0 3.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO25354.1 - 0.027 14.5 0.4 2.4 8.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KDO25354.1 - 0.035 13.5 0.2 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 KDO25354.1 - 0.039 13.4 1.2 5.7 6.3 0.1 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_17 PF13207.6 KDO25354.1 - 0.047 14.1 0.1 15 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 KDO25354.1 - 0.062 13.2 0.1 6.5 6.6 0.0 2.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 KDO25354.1 - 0.067 13.3 0.3 6.5 6.9 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KDO25354.1 - 0.15 11.8 0.1 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CSRNP_N PF16019.5 KDO25356.1 - 8.4e-10 38.9 0.2 1.4e-09 38.2 0.2 1.4 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus HA PF03457.14 KDO25356.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain MFS_3 PF05977.13 KDO25356.1 - 0.26 9.7 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector ABC_membrane PF00664.23 KDO25357.1 - 4.2e-75 252.9 19.5 2e-42 145.8 6.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO25357.1 - 5.4e-70 234.2 0.0 1.2e-34 119.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO25357.1 - 2.5e-12 46.7 0.4 0.00021 20.8 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO25357.1 - 2.6e-06 27.9 5.5 0.013 15.9 0.2 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KDO25357.1 - 2.9e-06 27.6 0.7 0.11 12.7 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO25357.1 - 3.4e-06 26.7 3.7 0.025 14.3 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KDO25357.1 - 6.3e-06 25.6 0.5 0.044 13.0 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin DUF87 PF01935.17 KDO25357.1 - 1.4e-05 25.3 0.6 0.027 14.6 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 KDO25357.1 - 3.6e-05 23.7 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 KDO25357.1 - 0.00011 21.5 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 KDO25357.1 - 0.00036 20.8 0.1 0.42 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KDO25357.1 - 0.00039 20.3 2.2 1.7 8.4 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO25357.1 - 0.00089 19.2 4.2 1 9.3 0.1 3.5 4 0 0 4 4 3 2 RsgA GTPase AAA_24 PF13479.6 KDO25357.1 - 0.00095 18.9 0.0 0.51 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO25357.1 - 0.001 19.6 0.0 0.21 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KDO25357.1 - 0.0013 17.6 2.7 0.16 10.7 0.1 3.1 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KDO25357.1 - 0.0021 17.7 2.9 0.24 10.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KDO25357.1 - 0.0022 17.7 4.1 1.9 8.2 1.0 4.0 3 1 1 4 4 4 2 AAA domain SbcCD_C PF13558.6 KDO25357.1 - 0.0037 17.5 3.1 3.5 7.9 0.2 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO25357.1 - 0.0037 17.4 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KDO25357.1 - 0.0058 16.5 0.1 4.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_7 PF12775.7 KDO25357.1 - 0.0069 15.9 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KDO25357.1 - 0.016 15.2 0.4 1.8 8.5 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KDO25357.1 - 0.025 14.0 0.0 5.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KDO25357.1 - 0.025 13.9 0.2 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KDO25357.1 - 0.036 14.5 0.1 13 6.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 KDO25357.1 - 0.043 13.3 1.9 4.8 6.6 0.1 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein MMR_HSR1 PF01926.23 KDO25357.1 - 0.045 13.8 0.2 5.7 7.1 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KDO25357.1 - 0.06 13.3 0.1 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 KDO25357.1 - 0.091 12.4 0.0 7.9 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 KDO25357.1 - 0.11 12.3 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-RVT PF13966.6 KDO25358.1 - 0.00095 19.8 0.1 0.00095 19.8 0.1 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase ADP_ribosyl_GH PF03747.14 KDO25360.1 - 0.027 14.2 1.5 0.043 13.5 1.5 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase bZIP_1 PF00170.21 KDO25364.1 - 1.3 9.1 7.5 2.7 8.2 7.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor Peptidase_C48 PF02902.19 KDO25366.1 - 0.00079 19.3 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CCDC32 PF14989.6 KDO25366.1 - 0.21 11.6 0.0 0.55 10.2 0.0 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing 32 PLAC8 PF04749.17 KDO25369.1 - 4.3e-17 62.9 23.2 6.4e-17 62.4 23.2 1.3 1 0 0 1 1 1 1 PLAC8 family NAGLU PF05089.12 KDO25370.1 - 1.2e-114 382.7 2.9 1.8e-114 382.2 2.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KDO25370.1 - 3.5e-64 216.9 3.1 5.7e-64 216.2 3.1 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain LRR_4 PF12799.7 KDO25371.1 - 0.001 19.4 0.1 2 8.9 0.0 4.7 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) HTH_23 PF13384.6 KDO25372.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF2745 PF10922.8 KDO25373.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) HTH_23 PF13384.6 KDO25373.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain AAA PF00004.29 KDO25376.1 - 2e-17 63.8 0.0 4.3e-16 59.5 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO25376.1 - 6.7e-05 23.3 0.0 0.00021 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KDO25376.1 - 0.00032 20.7 0.0 0.00092 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO25376.1 - 0.00093 19.0 0.0 0.0028 17.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KDO25376.1 - 0.0039 16.4 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KDO25376.1 - 0.0043 16.9 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO25376.1 - 0.0045 17.3 0.3 0.028 14.8 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KDO25376.1 - 0.0047 17.2 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO25376.1 - 0.0051 17.1 0.0 0.019 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KDO25376.1 - 0.0063 16.1 0.1 0.021 14.3 0.0 1.9 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KDO25376.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO25376.1 - 0.0091 16.2 0.0 0.043 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KDO25376.1 - 0.016 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KDO25376.1 - 0.017 14.9 0.0 0.057 13.2 0.0 1.9 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KDO25376.1 - 0.022 15.3 0.0 0.049 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KDO25376.1 - 0.027 13.7 0.1 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 KDO25376.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 KDO25376.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 KDO25376.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KDO25376.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO25376.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KDO25376.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 KDO25376.1 - 0.2 12.1 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO25376.1 - 0.28 11.0 2.3 0.61 9.9 0.0 2.5 3 0 0 3 3 2 0 P-loop containing region of AAA domain LRR_4 PF12799.7 KDO25380.1 - 0.013 15.9 2.1 2 8.9 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 KDO25381.1 - 0.035 14.5 2.7 35 5.0 0.0 5.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 KDO25382.1 - 4.8e-19 68.4 3.1 0.00012 22.8 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25382.1 - 1.4e-14 54.2 0.0 0.0011 19.2 0.0 5.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO25382.1 - 0.018 14.0 1.8 30 3.4 0.0 3.7 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KDO25382.1 - 0.11 12.0 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KDO25382.1 - 0.75 10.4 5.9 7.7 7.2 0.6 4.0 4 0 0 4 4 4 0 PQQ-like domain EBV-NA3 PF05009.12 KDO25383.1 - 0.096 12.2 0.2 0.16 11.4 0.1 1.2 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) BTB_2 PF02214.22 KDO25384.1 - 2e-10 40.9 0.0 3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain WHAMM-JMY_N PF15920.5 KDO25384.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated BTB_2 PF02214.22 KDO25385.1 - 5.1e-08 33.2 0.0 8.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KDO25386.1 - 2.4e-09 37.4 0.0 2.3e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Auxin_repressed PF05564.12 KDO25386.1 - 0.039 14.6 0.1 0.068 13.9 0.1 1.4 1 0 0 1 1 1 0 Dormancy/auxin associated protein Melibiase_2 PF16499.5 KDO25387.1 - 4.1e-34 118.1 0.0 1.3e-33 116.4 0.0 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KDO25387.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Melibiase LRR_4 PF12799.7 KDO25388.1 - 0.017 15.5 0.1 9.3 6.8 0.0 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KDO25389.1 - 7.6e-19 68.1 0.0 8.4e-11 42.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25389.1 - 1.5e-12 47.7 0.2 5.8e-06 26.8 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO25389.1 - 1.8e-11 44.0 0.1 5.5e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO25389.1 - 5e-10 38.7 0.6 3.1e-05 24.0 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO25389.1 - 7.9e-07 29.2 0.1 0.014 15.7 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ATG101 PF07855.12 KDO25390.1 - 5.8e-33 114.1 0.0 7e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Pkinase PF00069.25 KDO25391.1 - 3e-66 223.5 0.0 4.4e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25391.1 - 7.3e-34 117.2 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO25391.1 - 8.9e-06 26.2 0.0 2.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO25391.1 - 1.6e-05 25.1 0.0 3.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 KDO25391.1 - 0.0011 18.3 0.5 0.002 17.5 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO25391.1 - 0.0043 16.0 0.3 0.0063 15.5 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO25391.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO25391.1 - 0.06 13.3 0.5 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO25391.1 - 0.086 11.8 0.3 0.17 10.8 0.3 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YukC PF10140.9 KDO25391.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Dynein_light PF01221.18 KDO25393.1 - 1.4e-18 67.0 0.0 7.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Dynein light chain type 1 MINDY_DUB PF04424.13 KDO25394.1 - 6.9e-29 100.2 0.0 1.1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase vWA-TerF-like PF10138.9 KDO25394.1 - 0.036 14.2 0.4 0.084 13.0 0.4 1.6 1 1 0 1 1 1 0 vWA found in TerF C terminus RNase_T PF00929.24 KDO25395.1 - 7.3e-18 65.6 0.0 9.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.24 KDO25396.1 - 4.5e-07 30.5 0.0 5.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease SBP_bac_6 PF13343.6 KDO25397.1 - 2.8e-16 59.7 2.5 2.1e-15 56.8 2.5 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KDO25397.1 - 4.6e-07 30.1 12.3 9.3e-07 29.1 11.2 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KDO25397.1 - 0.013 15.3 1.4 0.034 13.9 1.4 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein RNase_T PF00929.24 KDO25398.1 - 2.3e-06 28.3 0.0 2.5e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Sec6 PF06046.13 KDO25399.1 - 1.9e-31 109.1 0.0 3.2e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF977 PF06163.11 KDO25400.1 - 0.19 11.7 0.1 3.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) BT1 PF03092.16 KDO25401.1 - 1.5e-13 49.9 9.1 1.3e-09 36.8 0.4 3.2 3 0 0 3 3 3 3 BT1 family CCDC71L PF15374.6 KDO25402.1 - 0.012 15.0 2.8 0.012 14.9 2.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CEND1 PF15677.5 KDO25402.1 - 0.22 12.0 4.8 0.44 11.1 5.0 1.5 1 1 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 CEND1 PF15677.5 KDO25403.1 - 0.029 14.9 0.9 0.03 14.9 0.9 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 PLAC8 PF04749.17 KDO25404.1 - 2.7e-19 70.0 12.9 3.5e-19 69.6 12.9 1.2 1 0 0 1 1 1 1 PLAC8 family DUF2516 PF10724.9 KDO25404.1 - 0.0011 19.2 2.3 0.0021 18.3 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2516) PLAC8 PF04749.17 KDO25405.1 - 1.1e-15 58.4 12.9 1.4e-15 58.1 12.9 1.1 1 0 0 1 1 1 1 PLAC8 family SNAP PF14938.6 KDO25406.1 - 4.3e-22 78.9 12.9 5.8e-22 78.4 12.9 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KDO25406.1 - 7e-07 28.9 5.2 9.9e-07 28.4 5.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 KDO25406.1 - 0.0012 19.1 5.8 0.0023 18.2 1.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat NSF PF02071.20 KDO25406.1 - 1 10.4 7.1 29 6.1 0.5 4.8 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat Trypsin PF00089.26 KDO25407.1 - 3.2e-48 164.5 2.0 3.7e-48 164.3 2.0 1.0 1 0 0 1 1 1 1 Trypsin TPR_2 PF07719.17 KDO25408.1 - 8.1e-08 31.8 0.7 0.00021 21.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25408.1 - 6.3e-07 28.9 1.1 0.00026 20.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25408.1 - 0.00015 21.9 0.5 0.00051 20.3 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25408.1 - 0.00027 20.9 0.9 0.0014 18.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_28 PF02636.17 KDO25408.1 - 0.0065 16.1 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_11 PF13414.6 KDO25408.1 - 0.034 13.8 0.3 0.45 10.2 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KDO25408.1 - 0.063 13.3 1.8 12 6.2 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25408.1 - 0.089 13.3 0.0 0.34 11.4 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4419 PF14388.6 KDO25409.1 - 5.1e-79 265.8 0.0 1.3e-77 261.2 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) DUF2431 PF10354.9 KDO25410.1 - 5.3e-42 143.9 0.0 8.5e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.8 KDO25410.1 - 0.011 16.0 1.1 0.018 15.3 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO25410.1 - 0.063 13.7 1.4 0.12 12.8 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KDO25410.1 - 0.14 12.5 0.4 0.22 11.9 0.4 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PAN_4 PF14295.6 KDO25411.1 - 0.011 15.6 3.0 0.011 15.6 3.0 2.8 3 0 0 3 3 3 0 PAN domain GlcNAc PF11397.8 KDO25412.1 - 5e-45 154.5 0.2 4.3e-37 128.4 0.9 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) PP2C PF00481.21 KDO25413.1 - 9.7e-55 186.0 0.0 1.3e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO25413.1 - 0.0023 17.6 0.0 0.017 14.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C ABC_tran PF00005.27 KDO25414.1 - 1.2e-17 64.7 0.0 2.7e-17 63.6 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO25414.1 - 3.3e-07 30.4 0.2 0.009 15.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO25414.1 - 0.00084 18.8 0.5 0.064 12.7 0.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO25414.1 - 0.0021 17.8 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KDO25414.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KDO25414.1 - 0.034 14.4 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 KDO25414.1 - 0.043 13.1 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_23 PF13476.6 KDO25414.1 - 0.044 14.3 0.2 0.12 12.9 0.2 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KDO25414.1 - 0.047 13.6 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KDO25414.1 - 0.063 13.0 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KDO25414.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_5 PF07728.14 KDO25414.1 - 0.13 12.3 0.2 0.62 10.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KDO25414.1 - 0.16 11.7 0.4 0.29 10.9 0.4 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KDO25414.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Dynamin_N PF00350.23 KDO25414.1 - 0.25 11.4 0.1 0.42 10.7 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 KDO25414.1 - 0.25 11.6 1.5 2 8.7 1.5 2.2 1 1 0 1 1 1 0 AAA domain GST_C_3 PF14497.6 KDO25416.1 - 3e-13 49.8 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO25416.1 - 3.8e-06 27.1 0.0 9.8e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO25416.1 - 0.00036 20.5 0.5 0.0062 16.5 0.4 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO25416.1 - 0.0054 16.9 0.1 0.034 14.4 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO25416.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sulfate_transp PF00916.20 KDO25417.1 - 3.1e-33 115.1 28.0 4.5e-33 114.5 28.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 KDO25417.1 - 5.3e-10 39.5 1.9 3.4e-09 36.9 1.9 2.4 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KDO25417.1 - 2.2e-05 24.0 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF2975 PF11188.8 KDO25417.1 - 0.016 15.1 2.3 0.016 15.1 2.3 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2975) MFS_MOT1 PF16983.5 KDO25417.1 - 0.069 13.6 40.4 0.027 14.9 8.5 4.8 4 1 0 4 4 4 0 Molybdate transporter of MFS superfamily Zn_ribbon_recom PF13408.6 KDO25418.1 - 0.0016 18.9 6.2 0.5 10.9 0.4 2.4 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Ribosomal_L32p PF01783.23 KDO25418.1 - 0.011 15.9 0.8 0.011 15.9 0.8 3.0 3 0 0 3 3 3 0 Ribosomal L32p protein family Rubredoxin_2 PF18073.1 KDO25418.1 - 0.39 10.5 2.1 0.47 10.2 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain ABC_membrane PF00664.23 KDO25419.1 - 1e-50 173.0 41.4 8.5e-31 107.6 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO25419.1 - 4.9e-49 166.4 0.0 1.1e-27 97.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO25419.1 - 1.7e-07 30.9 0.0 0.0034 16.8 0.6 3.4 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO25419.1 - 7.2e-06 26.0 0.1 0.025 14.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO25419.1 - 8.1e-06 25.9 0.3 0.039 14.0 0.1 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO25419.1 - 0.0019 17.9 0.6 2.7 7.8 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO25419.1 - 0.0019 18.6 0.5 1.1 9.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KDO25419.1 - 0.004 16.9 0.3 1.8 8.3 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO25419.1 - 0.0052 17.2 0.4 2.8 8.3 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 KDO25419.1 - 0.011 16.0 1.6 3 8.1 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KDO25419.1 - 0.013 15.3 0.0 7 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KDO25419.1 - 0.044 13.3 0.2 4.2 6.9 0.0 2.8 2 1 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KDO25419.1 - 0.079 12.1 0.1 7.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KDO25419.1 - 0.079 13.4 0.1 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO25419.1 - 0.15 12.1 0.4 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KDO25419.1 - 0.17 11.9 3.0 4 7.5 0.6 2.6 2 0 0 2 2 2 0 Dynamin family dNK PF01712.19 KDO25419.1 - 0.19 11.6 0.9 14 5.5 0.0 3.4 4 0 0 4 4 4 0 Deoxynucleoside kinase ABC_tran PF00005.27 KDO25420.1 - 7e-49 165.9 0.0 2.4e-27 96.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO25420.1 - 3.4e-48 164.7 31.8 2.8e-25 89.5 8.4 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO25420.1 - 5.5e-06 26.0 3.8 0.0037 16.7 0.6 3.6 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO25420.1 - 9.4e-06 25.7 0.2 0.035 14.2 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO25420.1 - 1.3e-05 25.1 0.1 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO25420.1 - 0.0019 18.6 0.5 1.2 9.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO25420.1 - 0.0025 17.5 0.2 2.7 7.8 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KDO25420.1 - 0.0043 17.4 0.4 2.8 8.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.17 KDO25420.1 - 0.0073 16.1 0.3 1.7 8.4 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO25420.1 - 0.011 16.0 1.4 3.2 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO25420.1 - 0.03 13.5 0.0 3.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 KDO25420.1 - 0.037 13.8 0.1 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO25420.1 - 0.081 13.4 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO25420.1 - 0.16 12.0 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KDO25420.1 - 1.4 8.9 6.1 4 7.5 0.6 2.7 3 0 0 3 3 2 0 Dynamin family ABC_tran PF00005.27 KDO25421.1 - 3.5e-49 166.9 0.0 1.1e-27 97.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO25421.1 - 7.9e-48 163.5 40.8 1.1e-27 97.4 13.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO25421.1 - 1.6e-07 31.0 0.0 0.0035 16.8 0.6 3.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO25421.1 - 1e-05 25.6 0.3 0.04 14.0 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO25421.1 - 1.4e-05 25.1 0.2 0.034 14.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO25421.1 - 0.0028 18.1 0.7 1.3 9.4 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KDO25421.1 - 0.0033 17.1 0.3 2.8 7.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KDO25421.1 - 0.0058 17.0 0.4 2.9 8.3 0.0 3.3 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.17 KDO25421.1 - 0.0065 16.2 0.3 1.7 8.3 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO25421.1 - 0.022 15.0 2.9 3.2 8.0 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.6 KDO25421.1 - 0.029 14.2 0.0 11 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KDO25421.1 - 0.051 12.7 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KDO25421.1 - 0.081 13.4 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO25421.1 - 0.16 12.1 0.3 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KDO25421.1 - 0.18 11.9 3.0 4 7.5 0.6 2.6 2 0 0 2 2 2 0 Dynamin family NOA36 PF06524.12 KDO25422.1 - 0.0023 17.3 0.2 0.004 16.5 0.2 1.3 1 0 0 1 1 1 1 NOA36 protein Cys_rich_KTR PF14205.6 KDO25422.1 - 0.066 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR Lar_restr_allev PF14354.6 KDO25422.1 - 0.26 11.7 1.0 0.66 10.4 0.1 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Kinesin PF00225.23 KDO25423.1 - 5.6e-49 166.9 0.0 7e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO25423.1 - 9.1e-12 45.1 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KDO25423.1 - 9e-05 22.9 0.2 0.00018 21.9 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain PP2C PF00481.21 KDO25424.1 - 2e-28 99.7 0.0 3e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PHO4 PF01384.20 KDO25425.1 - 5.9e-52 176.8 8.1 7.9e-52 176.4 8.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Multi_Drug_Res PF00893.19 KDO25425.1 - 0.067 13.9 5.0 0.18 12.5 0.6 3.1 2 0 0 2 2 2 0 Small Multidrug Resistance protein PP2C PF00481.21 KDO25427.1 - 6.4e-29 101.4 0.0 2.6e-28 99.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3459 PF11941.8 KDO25427.1 - 0.026 14.9 0.1 0.066 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) cNMP_binding PF00027.29 KDO25428.1 - 2.7e-17 62.6 0.1 4.4e-08 33.1 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ubiquitin PF00240.23 KDO25428.1 - 1.4e-10 40.8 0.0 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO25428.1 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO25428.1 - 0.02 15.3 0.0 0.05 14.1 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain VASt PF16016.5 KDO25430.1 - 4.3e-27 95.4 1.1 6.1e-27 94.9 1.1 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Glycoprotein PF03409.15 KDO25430.1 - 0.066 12.1 0.2 0.079 11.8 0.2 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein CAF1 PF04857.20 KDO25430.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease adh_short PF00106.25 KDO25432.1 - 4.3e-22 78.5 0.0 5.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO25432.1 - 5.8e-18 65.3 0.1 4.4e-11 42.8 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Spt4 PF06093.13 KDO25432.1 - 0.053 13.6 0.6 0.13 12.3 0.6 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Zn-ribbon_8 PF09723.10 KDO25432.1 - 0.055 13.6 0.6 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ank_3 PF13606.6 KDO25433.1 - 0.15 12.7 0.2 0.93 10.3 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeat Hist_deacetyl PF00850.19 KDO25434.1 - 5.7e-88 295.3 0.0 1e-87 294.5 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain DUF3246 PF11596.8 KDO25434.1 - 1.1 8.6 8.4 0.57 9.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF3522 PF12036.8 KDO25435.1 - 2.9e-29 102.7 12.5 5.1e-29 101.9 12.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) PPC PF04151.15 KDO25435.1 - 0.034 15.2 1.9 0.11 13.6 0.0 2.7 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain EGF PF00008.27 KDO25435.1 - 1 9.7 7.3 3.9 7.9 7.3 2.1 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 KDO25435.1 - 3.3 7.9 8.0 2.2 8.5 5.3 2.2 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 KDO25435.1 - 4 7.9 14.6 0.48 10.8 9.4 2.3 2 0 0 2 2 2 0 EGF-like domain WD40 PF00400.32 KDO25436.1 - 1.4e-15 57.4 6.6 0.0013 19.5 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KDO25436.1 - 1.8e-06 26.9 0.2 0.0064 15.2 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KDO25436.1 - 0.012 16.1 0.6 18 5.9 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain Ribosomal_S27e PF01667.17 KDO25436.1 - 0.04 13.6 0.1 0.44 10.3 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S27 DIOX_N PF14226.6 KDO25437.1 - 6.7e-23 81.7 0.0 1.8e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO25437.1 - 3.2e-19 69.3 0.0 5.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipase_3 PF01764.25 KDO25438.1 - 1.2e-31 109.4 0.0 3.2e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Cutinase PF01083.22 KDO25438.1 - 1.9e-06 28.0 0.0 3.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.20 KDO25438.1 - 0.00041 20.5 0.1 0.00073 19.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KDO25438.1 - 0.00077 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KDO25438.1 - 0.0011 18.6 0.1 0.0075 15.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KDO25438.1 - 0.0035 18.0 2.8 0.0054 17.4 2.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KDO25438.1 - 0.0095 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase PGAP1 PF07819.13 KDO25438.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein YAcAr PF10686.9 KDO25438.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family PE-PPE PF08237.11 KDO25438.1 - 0.033 13.7 0.0 0.073 12.6 0.0 1.5 1 1 0 1 1 1 0 PE-PPE domain FGGY_N PF00370.21 KDO25439.1 - 9.4e-22 77.8 0.0 8.7e-21 74.6 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KDO25439.1 - 0.00054 19.5 0.4 0.28 10.6 0.1 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF1340 PF07067.11 KDO25439.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Spc7 PF08317.11 KDO25440.1 - 0.00048 19.1 7.1 0.00048 19.1 7.1 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein CH PF00307.31 KDO25440.1 - 0.0062 16.7 0.1 0.025 14.8 0.1 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Rootletin PF15035.6 KDO25440.1 - 0.99 9.4 11.7 0.83 9.6 0.7 3.4 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF572 PF04502.13 KDO25440.1 - 8.2 5.9 10.7 1.9 8.0 6.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF572) DSPc PF00782.20 KDO25441.1 - 4e-22 78.5 0.0 6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PRKCSH-like PF12999.7 KDO25443.1 - 1.9e-20 73.4 3.3 3.2e-20 72.7 3.3 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KDO25443.1 - 1.1e-06 28.4 1.1 4e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 KDO25443.1 - 0.0031 17.7 10.0 0.009 16.2 5.9 2.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A ATG27 PF09451.10 KDO25443.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 UPF0126 PF03458.13 KDO25444.1 - 2.4e-37 126.7 12.6 1.4e-18 66.5 2.8 2.4 2 0 0 2 2 2 2 UPF0126 domain UPF0126 PF03458.13 KDO25445.1 - 7.3e-38 128.3 16.3 9.9e-19 67.0 4.0 2.6 2 0 0 2 2 2 2 UPF0126 domain FYVE PF01363.21 KDO25446.1 - 3.1e-13 49.7 5.2 3.1e-13 49.7 5.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger Ank_4 PF13637.6 KDO25446.1 - 0.0032 18.0 0.2 0.03 14.9 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25446.1 - 0.12 13.0 0.2 1.4 9.7 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat Radial_spoke_3 PF06098.11 KDO25447.1 - 0.0078 15.5 0.3 0.013 14.7 0.3 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 GAIN_A PF18619.1 KDO25447.1 - 0.028 14.6 1.9 4.1 7.7 0.1 2.7 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A SOGA PF11365.8 KDO25447.1 - 0.052 14.7 0.7 1.1 10.5 0.7 2.5 1 1 1 2 2 2 0 Protein SOGA KxDL PF10241.9 KDO25447.1 - 0.33 11.2 3.0 0.46 10.8 1.7 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein UPF0242 PF06785.11 KDO25448.1 - 4.4 7.4 36.6 0.12 12.4 6.9 4.4 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus UNC-50 PF05216.13 KDO25449.1 - 4.1e-68 229.2 20.2 5.3e-68 228.9 20.2 1.1 1 0 0 1 1 1 1 UNC-50 family Bromodomain PF00439.25 KDO25449.1 - 2.2e-07 30.8 0.0 5.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain YfzA PF14118.6 KDO25449.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.0 2 0 0 2 2 2 0 YfzA-like protein Bromodomain PF00439.25 KDO25450.1 - 5.6e-76 250.7 0.3 1.9e-17 63.1 0.0 6.5 6 0 0 6 6 6 6 Bromodomain AP3D1 PF06375.11 KDO25450.1 - 3.4 7.9 31.7 0.046 14.0 10.0 2.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Selenoprotein_S PF06936.11 KDO25451.1 - 7.1 6.4 11.1 0.47 10.2 4.8 2.1 3 0 0 3 3 3 0 Selenoprotein S (SelS) Acyl-CoA_dh_1 PF00441.24 KDO25452.1 - 1.9e-50 170.9 4.7 4.5e-50 169.8 4.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KDO25452.1 - 1.5e-35 122.3 0.2 5.7e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KDO25452.1 - 4.8e-24 85.2 3.8 8.5e-24 84.3 3.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KDO25452.1 - 2.4e-23 82.2 0.1 4.5e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 KDO25452.1 - 0.0021 17.8 0.1 0.0043 16.8 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MscS_porin PF12795.7 KDO25453.1 - 0.001 18.7 12.5 0.0012 18.4 12.5 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain PI3K_P85_iSH2 PF16454.5 KDO25453.1 - 0.0032 17.1 0.6 0.0055 16.3 0.6 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 KDO25453.1 - 0.034 13.0 6.3 0.041 12.8 6.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KDO25453.1 - 0.043 13.9 12.3 0.056 13.5 12.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 KDO25453.1 - 0.043 13.0 0.3 0.05 12.8 0.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 UPF0242 PF06785.11 KDO25453.1 - 0.098 12.8 1.4 0.13 12.4 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KDO25453.1 - 0.14 12.2 3.3 0.28 11.2 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SOCS PF12610.8 KDO25453.1 - 0.16 12.4 0.5 0.64 10.5 0.1 2.2 3 0 0 3 3 3 0 Suppressor of cytokine signalling SesA PF17107.5 KDO25453.1 - 0.23 11.6 6.9 0.29 11.3 4.4 1.9 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MukF_M PF17192.4 KDO25453.1 - 0.24 11.2 6.7 4.4 7.0 6.7 2.0 1 1 0 1 1 1 0 MukF middle domain TEX13 PF15186.6 KDO25453.1 - 0.96 9.1 10.0 0.58 9.8 7.3 1.8 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF3416 PF11896.8 KDO25453.1 - 1 9.6 11.8 3.1 8.0 11.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) APG6_N PF17675.1 KDO25453.1 - 1.2 9.6 9.7 3.2 8.3 9.5 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 KDO25453.1 - 1.3 8.3 13.8 1.7 7.9 13.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KDO25453.1 - 2.4 8.6 7.1 32 5.1 6.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB PX PF00787.24 KDO25454.1 - 3.7e-06 26.9 0.0 4.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 PX domain MIP PF00230.20 KDO25456.1 - 2.2e-05 24.3 2.5 9.2e-05 22.2 2.3 2.0 1 1 1 2 2 2 2 Major intrinsic protein SlyX PF04102.12 KDO25456.1 - 0.052 14.2 0.6 0.052 14.2 0.6 3.8 1 1 2 3 3 3 0 SlyX ABC_tran_CTD PF16326.5 KDO25456.1 - 0.16 12.2 6.3 0.15 12.3 3.2 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain T3SS_basalb_I PF17001.5 KDO25456.1 - 0.38 11.4 4.2 0.51 11.0 1.9 2.3 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI FAM184 PF15665.5 KDO25456.1 - 0.53 10.0 22.3 0.79 9.5 22.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TSC22 PF01166.18 KDO25456.1 - 0.99 9.8 6.7 0.39 11.1 0.9 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family LCD1 PF09798.9 KDO25456.1 - 1.4 7.4 12.6 1.3 7.4 6.7 2.0 1 1 1 2 2 2 0 DNA damage checkpoint protein betaPIX_CC PF16523.5 KDO25456.1 - 4.3 7.2 8.8 0.2 11.5 2.4 2.1 2 0 0 2 2 2 0 betaPIX coiled coil LMF1 PF06762.14 KDO25457.1 - 1.3e-92 311.3 4.8 1.8e-92 310.8 4.8 1.1 1 0 0 1 1 1 1 Lipase maturation factor HMMR_C PF15908.5 KDO25458.1 - 5e-08 33.4 6.5 1.7e-07 31.7 0.9 2.2 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 KDO25458.1 - 0.0041 17.7 7.5 0.0042 17.7 0.4 3.0 2 1 1 3 3 3 1 Initiation control protein YabA UPF0242 PF06785.11 KDO25458.1 - 0.0079 16.3 4.7 0.071 13.2 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KDO25458.1 - 0.024 15.1 2.7 0.024 15.1 2.7 3.4 3 1 1 4 4 3 0 Cell division protein ZapB Chibby PF14645.6 KDO25458.1 - 0.04 14.3 3.4 1.8 9.0 0.2 2.6 2 1 0 2 2 2 0 Chibby family APG6_N PF17675.1 KDO25458.1 - 0.052 14.1 1.6 0.052 14.1 1.6 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KDO25458.1 - 0.12 12.6 22.3 0.13 12.5 1.3 3.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 KDO25458.1 - 0.29 11.5 8.0 0.2 12.0 1.0 3.0 2 1 0 3 3 3 0 Csm1 N-terminal domain HAUS-augmin3 PF14932.6 KDO25458.1 - 0.34 10.4 10.4 0.61 9.6 1.2 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1192 PF06698.11 KDO25458.1 - 0.37 10.9 0.0 0.37 10.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) KASH_CCD PF14662.6 KDO25458.1 - 0.38 10.5 15.0 0.25 11.2 9.4 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 KDO25458.1 - 0.44 10.7 10.4 3.6 7.8 2.1 4.0 3 2 1 4 4 4 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 KDO25458.1 - 0.47 10.7 11.6 0.2 11.9 0.8 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 KDO25458.1 - 0.74 9.6 5.7 0.44 10.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ERM PF00769.19 KDO25458.1 - 1.1 9.0 17.4 3.1 7.6 4.3 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fez1 PF06818.15 KDO25458.1 - 4.8 7.6 12.1 46 4.4 11.5 2.1 1 1 1 2 2 2 0 Fez1 NRBF2 PF08961.10 KDO25458.1 - 5.1 6.7 17.1 0.34 10.5 3.1 3.3 1 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator PRKG1_interact PF15898.5 KDO25458.1 - 7.6 7.5 16.5 9.1 7.3 3.0 3.5 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 KDO25458.1 - 7.8 6.7 29.5 2.6 8.2 6.0 4.4 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 Pkinase PF00069.25 KDO25459.1 - 1.6e-57 194.9 0.0 2.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25459.1 - 8.2e-28 97.4 0.0 1.2e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KDO25459.1 - 5.8e-09 36.2 0.0 3.6e-08 33.7 0.0 2.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KDO25459.1 - 0.00065 19.1 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KDO25459.1 - 0.011 14.7 0.2 0.017 14.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4383 PF14325.6 KDO25459.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) Pkinase_fungal PF17667.1 KDO25459.1 - 0.18 10.6 0.0 0.37 9.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S28 PF05577.12 KDO25461.1 - 2.6e-64 217.6 0.0 2.9e-53 181.2 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KDO25461.1 - 1.8e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 KDO25461.1 - 5.7e-05 22.0 0.0 9.2e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 KDO25461.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO25461.1 - 0.032 13.7 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 KDO25461.1 - 0.051 12.7 0.1 0.075 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 KDO25461.1 - 0.48 11.0 12.7 7.1 7.2 12.4 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DEAD PF00270.29 KDO25463.1 - 8.3e-36 123.4 0.1 1.3e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO25463.1 - 5.4e-24 84.7 0.0 1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO25463.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KDO25463.1 - 0.019 15.3 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 KDO25463.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF4419 PF14388.6 KDO25464.1 - 8.1e-104 347.3 0.0 9.2e-104 347.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TrbE PF11100.8 KDO25464.1 - 0.0019 18.4 0.3 0.016 15.4 0.1 2.2 2 0 0 2 2 2 1 Conjugal transfer protein TrbE TPR_2 PF07719.17 KDO25465.1 - 0.00012 21.9 0.3 4.3 7.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25465.1 - 0.003 17.6 0.6 0.37 11.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Voltage_CLC PF00654.20 KDO25465.1 - 0.0053 16.0 0.8 0.0076 15.5 0.8 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel TPR_17 PF13431.6 KDO25465.1 - 0.0082 16.5 0.3 0.24 11.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25465.1 - 0.012 15.4 0.4 13 5.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25465.1 - 0.033 14.7 0.0 0.79 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3671 PF12420.8 KDO25465.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function TPR_11 PF13414.6 KDO25465.1 - 0.14 11.8 0.0 1 9.1 0.0 2.4 3 0 0 3 3 3 0 TPR repeat SAYSvFN PF10260.9 KDO25466.1 - 1.3e-14 53.9 0.0 5.8e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) UPF0184 PF03670.13 KDO25466.1 - 0.056 13.8 2.9 0.27 11.7 2.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) LRR_8 PF13855.6 KDO25467.1 - 1.2e-21 76.2 28.3 6e-09 35.5 1.0 4.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KDO25467.1 - 9.9e-16 57.6 13.6 0.00025 21.3 0.9 4.8 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO25467.1 - 0.0017 18.6 14.2 1.6 9.6 0.2 6.1 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KDO25467.1 - 0.0054 16.7 13.3 1.1 9.5 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KDO25467.1 - 0.0063 16.0 3.3 0.76 9.3 0.1 2.9 1 1 1 3 3 3 2 Leucine-rich repeat Pkinase PF00069.25 KDO25470.1 - 5.9e-63 212.7 0.0 6.5e-62 209.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25470.1 - 1.8e-31 109.3 0.1 1.4e-25 90.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO25470.1 - 0.0018 17.3 0.2 0.0028 16.7 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO25470.1 - 0.096 12.6 0.1 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KDO25470.1 - 0.099 12.2 0.1 0.24 11.0 0.1 1.6 2 0 0 2 2 2 0 RIO1 family His_Phos_1 PF00300.22 KDO25471.1 - 6.3e-30 104.3 2.5 1.4e-29 103.2 2.5 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NAD_kinase PF01513.21 KDO25471.1 - 1.2e-16 60.8 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KDO25471.1 - 0.023 14.3 0.0 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF4056 PF13265.6 KDO25471.1 - 0.041 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) DUF900 PF05990.12 KDO25471.1 - 0.068 12.7 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Tubulin PF00091.25 KDO25472.1 - 4.6e-68 229.3 0.0 8e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO25472.1 - 3.8e-41 140.2 0.2 5.7e-41 139.6 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KDO25472.1 - 0.00083 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KDO25472.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KDO25472.1 - 0.012 14.9 0.0 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Abhydrolase_2 PF02230.16 KDO25473.1 - 2.5e-50 171.3 0.1 5e-40 137.6 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KDO25473.1 - 6.8e-06 26.8 2.3 1.1e-05 26.1 2.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KDO25473.1 - 0.00028 20.6 0.0 0.0021 17.8 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KDO25473.1 - 0.00038 20.4 0.1 0.023 14.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Cutinase PF01083.22 KDO25473.1 - 0.00057 19.9 0.1 0.0035 17.3 0.0 1.9 1 1 1 2 2 2 1 Cutinase Thioesterase PF00975.20 KDO25473.1 - 0.00069 19.8 0.1 0.0042 17.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.21 KDO25473.1 - 0.007 15.9 1.3 0.11 12.0 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 KDO25473.1 - 0.0097 15.5 0.1 1.8 8.1 0.0 2.2 1 1 1 2 2 2 2 Dienelactone hydrolase family PE-PPE PF08237.11 KDO25473.1 - 0.023 14.2 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DnaJ PF00226.31 KDO25475.1 - 1.4e-23 82.8 4.5 2.6e-23 81.9 4.5 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 KDO25475.1 - 2.5e-09 37.1 0.0 2.1e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KDO25475.1 - 3.3e-05 23.9 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain TPR_19 PF14559.6 KDO25476.1 - 1.4e-06 28.7 0.6 0.00016 22.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25476.1 - 0.00041 20.9 0.1 0.00041 20.9 0.1 2.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO25476.1 - 0.00048 20.6 2.4 3.4 8.5 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25476.1 - 0.00061 19.7 0.6 1.7 8.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25476.1 - 0.054 13.8 1.2 0.77 10.1 0.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat YccV-like PF08755.11 KDO25476.1 - 0.063 13.8 0.2 0.18 12.4 0.2 1.8 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like TPR_14 PF13428.6 KDO25476.1 - 0.18 12.7 12.0 5.2 8.1 0.2 5.2 4 1 2 6 6 6 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 KDO25477.1 - 2.3e-09 37.4 9.6 2.3e-09 37.4 9.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KDO25477.1 - 1.6e-05 24.5 9.5 3.8e-05 23.3 9.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger PHD PF00628.29 KDO25477.1 - 2.6e-05 24.0 6.0 2.6e-05 24.0 6.0 2.5 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 KDO25477.1 - 3.7e-05 23.9 11.2 3.7e-05 23.9 11.2 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO25477.1 - 6.6e-05 22.7 10.4 0.00014 21.6 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Med26 PF08711.11 KDO25477.1 - 0.00013 22.0 0.1 0.00038 20.4 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-C3HC4_3 PF13920.6 KDO25477.1 - 0.00039 20.2 6.2 0.00039 20.2 6.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO25477.1 - 0.00048 19.9 9.4 0.00048 19.9 9.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO25477.1 - 0.00054 19.9 4.1 0.00072 19.5 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-HC5HC2H PF13771.6 KDO25477.1 - 0.00099 19.3 12.6 0.31 11.3 4.0 2.6 1 1 1 2 2 2 2 PHD-like zinc-binding domain zf-UDP PF14569.6 KDO25477.1 - 0.0033 17.5 2.7 0.0033 17.5 2.7 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger OmdA PF13376.6 KDO25477.1 - 0.0054 16.7 0.1 0.0054 16.7 0.1 2.7 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated zf-ANAPC11 PF12861.7 KDO25477.1 - 0.0055 16.7 8.2 0.021 14.9 8.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO25477.1 - 0.067 13.2 10.4 0.061 13.3 8.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Importin_rep_4 PF18808.1 KDO25477.1 - 0.081 13.2 1.2 7.5 6.9 1.1 2.5 2 0 0 2 2 2 0 Importin repeat zf-HC5HC2H_2 PF13832.6 KDO25477.1 - 0.092 12.9 13.4 4 7.7 4.6 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain Nucleoside_tran PF01733.18 KDO25478.1 - 4e-37 128.3 19.9 5.3e-37 127.9 14.3 2.8 1 1 0 2 2 2 1 Nucleoside transporter PH PF00169.29 KDO25481.1 - 7.1e-10 39.3 0.2 1.3e-09 38.5 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KDO25481.1 - 0.0031 17.4 0.1 0.005 16.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO25481.1 - 0.012 15.9 0.5 0.017 15.4 0.5 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO25481.1 - 0.022 14.8 1.7 0.29 11.2 1.7 2.2 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 KDO25481.1 - 3.2 8.2 6.6 12 6.4 1.1 2.6 2 1 0 3 3 3 0 Pleckstrin homology domain GAF_2 PF13185.6 KDO25482.1 - 4.6e-15 56.1 10.2 0.0015 18.8 0.0 6.5 6 1 0 6 6 6 4 GAF domain SAM_1 PF00536.30 KDO25482.1 - 1.3e-07 31.9 0.0 2.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_7 PF13499.6 KDO25482.1 - 1.6e-06 28.4 0.6 3.3e-06 27.4 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair GAF PF01590.26 KDO25482.1 - 6.5e-05 23.6 11.4 0.028 15.0 0.1 5.7 6 0 0 6 6 6 2 GAF domain GAF_3 PF13492.6 KDO25482.1 - 0.0001 22.7 6.9 0.004 17.5 0.1 4.8 5 0 0 5 5 5 1 GAF domain EF-hand_8 PF13833.6 KDO25482.1 - 0.00019 21.2 3.6 0.02 14.8 0.5 2.6 1 1 1 2 2 2 2 EF-hand domain pair IQ PF00612.27 KDO25482.1 - 0.00043 19.8 0.8 0.00043 19.8 0.8 4.2 3 0 0 3 3 3 1 IQ calmodulin-binding motif EF-hand_6 PF13405.6 KDO25482.1 - 0.02 14.8 0.5 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain DUF2064 PF09837.9 KDO25482.1 - 0.021 14.7 0.3 0.22 11.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) EF-hand_1 PF00036.32 KDO25482.1 - 0.11 12.1 2.3 0.11 12.1 0.2 2.1 2 0 0 2 2 2 0 EF hand SAM_2 PF07647.17 KDO25482.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) OST-HTH PF12872.7 KDO25482.1 - 0.17 11.7 0.0 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 OST-HTH/LOTUS domain DUF1336 PF07059.12 KDO25483.1 - 1.1e-46 159.7 0.0 1.6e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 KDO25483.1 - 1.5e-14 54.3 0.0 2.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO25483.1 - 0.00033 21.0 4.1 0.0018 18.6 4.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO25483.1 - 0.012 15.9 0.3 0.054 13.8 0.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Mg_trans_NIPA PF05653.14 KDO25484.1 - 9.1e-39 133.3 19.1 6e-25 87.9 6.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA TMEM234 PF10639.9 KDO25484.1 - 0.0039 17.2 1.1 0.011 15.8 1.1 1.8 1 0 0 1 1 1 1 Putative transmembrane family 234 TipAS PF07739.13 KDO25484.1 - 0.11 13.1 0.2 0.2 12.2 0.2 1.3 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain YfhO PF09586.10 KDO25484.1 - 0.23 9.6 7.4 1.8 6.7 0.6 2.1 2 0 0 2 2 2 0 Bacterial membrane protein YfhO ERGIC_N PF13850.6 KDO25484.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.0 4 0 0 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ABC2_membrane PF01061.24 KDO25485.1 - 6.1e-32 110.8 10.3 7.7e-32 110.4 10.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO25485.1 - 1.4e-06 28.9 0.1 0.001 19.6 0.0 2.3 1 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO25485.1 - 0.0024 17.8 0.0 2.1 8.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KDO25485.1 - 0.0024 17.0 4.7 0.0024 17.0 4.7 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KDO25485.1 - 0.0049 16.6 0.1 0.0092 15.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO25485.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KDO25485.1 - 0.033 14.6 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KDO25485.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KDO25485.1 - 0.18 11.2 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DnaJ_C PF01556.18 KDO25486.1 - 3.9e-34 117.9 0.0 5.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO25486.1 - 2.7e-28 97.9 1.1 4.4e-28 97.2 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain FYVE PF01363.21 KDO25487.1 - 6.3e-17 61.5 8.9 1.2e-16 60.5 8.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO25487.1 - 1.2e-06 29.2 0.1 2.6e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 GAF domain HTH_9 PF08221.11 KDO25488.1 - 1.5e-07 31.4 1.2 4e-05 23.6 0.2 3.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KDO25488.1 - 5e-07 29.7 2.4 0.025 14.4 0.4 4.2 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 KDO25488.1 - 0.00016 21.5 1.1 0.0025 17.7 0.1 2.7 3 0 0 3 3 3 1 TFIIE alpha subunit SbcD_C PF12320.8 KDO25488.1 - 4.3 7.7 7.0 2 8.8 0.2 3.3 4 0 0 4 4 4 0 Type 5 capsule protein repressor C-terminal domain SH3BGR PF04908.15 KDO25489.1 - 0.032 14.4 0.2 0.074 13.2 0.2 1.8 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein CRAL_TRIO PF00650.20 KDO25490.1 - 1.4e-28 99.7 0.0 1.7e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KDO25490.1 - 2e-07 31.2 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1754 PF08555.10 KDO25491.1 - 4.5e-06 27.4 4.6 4.5e-06 27.4 4.6 2.3 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) TLP-20 PF06088.11 KDO25491.1 - 0.029 14.3 1.9 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pox_Ag35 PF03286.14 KDO25491.1 - 0.037 13.8 0.6 0.037 13.8 0.6 1.9 1 1 1 2 2 2 0 Pox virus Ag35 surface protein RRP7 PF12923.7 KDO25491.1 - 0.24 11.5 8.8 0.33 11.1 2.6 2.4 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain BPL_LplA_LipB PF03099.19 KDO25492.1 - 1.1e-17 64.1 0.0 1.9e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KDO25492.1 - 6.2e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Ofd1_CTDD PF10637.9 KDO25493.1 - 1.2e-59 201.8 0.0 1.7e-56 191.5 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KDO25493.1 - 1.4e-23 83.4 0.0 4.8e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KDO25493.1 - 4.1e-13 50.0 0.0 7.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KDO25494.1 - 2.4e-46 158.2 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25494.1 - 3.9e-46 157.4 0.0 6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO25494.1 - 5.1e-05 23.6 9.3 0.012 16.0 0.8 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) SKG6 PF08693.10 KDO25494.1 - 0.014 14.8 3.0 0.014 14.8 3.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KDO25494.1 - 0.029 14.1 0.8 0.029 14.1 0.8 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 KDO25494.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Rifin LRR_8 PF13855.6 KDO25494.1 - 0.054 13.3 2.4 3.2 7.6 0.1 2.8 2 1 0 2 2 2 0 Leucine rich repeat APH PF01636.23 KDO25494.1 - 0.09 12.7 0.0 0.52 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO25494.1 - 0.098 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Syndecan PF01034.20 KDO25494.1 - 0.21 11.5 1.0 0.5 10.3 1.0 1.6 1 0 0 1 1 1 0 Syndecan domain cobW PF02492.19 KDO25495.1 - 8.4e-47 159.0 0.5 1.2e-46 158.6 0.5 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KDO25495.1 - 1.1e-10 41.3 0.1 3.3e-10 39.7 0.1 1.9 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KDO25495.1 - 0.027 14.4 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KDO25495.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 KDO25495.1 - 0.087 12.3 0.1 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KDO25495.1 - 0.1 13.1 0.2 4.7 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KDO25495.1 - 0.23 10.4 0.5 2.4 7.1 0.5 2.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SelP_N PF04592.14 KDO25495.1 - 1.4 8.3 8.9 2.3 7.5 8.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M24 PF00557.24 KDO25496.1 - 1.4e-50 172.0 0.1 1.7e-50 171.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KDO25496.1 - 2.3e-17 63.0 7.4 4e-17 62.3 7.4 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KDO25496.1 - 0.00021 21.3 4.7 0.00047 20.2 4.7 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KDO25496.1 - 0.0097 15.8 6.3 0.019 14.9 6.3 1.5 1 0 0 1 1 1 1 HIT zinc finger WD40 PF00400.32 KDO25497.1 - 5.3e-50 166.3 58.1 0.0056 17.5 0.4 24.5 26 1 0 26 26 24 12 WD domain, G-beta repeat HELP PF03451.14 KDO25497.1 - 1.8e-35 120.6 0.5 2.8e-19 68.7 0.1 4.1 4 0 0 4 4 4 3 HELP motif ANAPC4_WD40 PF12894.7 KDO25497.1 - 9.4e-23 80.3 6.6 0.0025 18.1 0.0 12.5 9 4 4 13 13 13 4 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 KDO25497.1 - 1.2e-05 24.8 0.2 0.19 11.7 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain PQQ_2 PF13360.6 KDO25497.1 - 3.5e-05 23.5 0.6 0.031 13.9 0.1 3.9 3 0 0 3 3 3 1 PQQ-like domain EF-hand_1 PF00036.32 KDO25497.1 - 3.8e-05 22.9 0.3 0.64 9.7 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO25497.1 - 3.9e-05 24.0 0.0 0.43 11.1 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain pair Ge1_WD40 PF16529.5 KDO25497.1 - 0.00012 21.2 2.2 0.25 10.3 0.0 5.5 6 1 0 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_5 PF13202.6 KDO25497.1 - 0.0058 16.1 0.1 2 8.1 0.0 2.7 2 0 0 2 2 2 1 EF hand PD40 PF07676.12 KDO25497.1 - 0.0067 16.4 0.5 38 4.4 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KDO25497.1 - 0.083 11.9 0.3 8.7 5.3 0.0 3.8 4 1 0 4 4 4 0 Coatomer WD associated region Trypsin PF00089.26 KDO25498.1 - 1.2e-44 152.8 0.1 1.4e-44 152.6 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KDO25498.1 - 3.3e-05 24.8 0.2 7.7e-05 23.6 0.2 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-C3HC4_2 PF13923.6 KDO25499.1 - 4.7e-09 35.9 8.3 8.1e-09 35.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO25499.1 - 1.9e-08 34.0 7.6 3.5e-08 33.2 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO25499.1 - 3.7e-06 26.8 4.6 3.7e-06 26.8 4.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO25499.1 - 4.9e-06 26.4 8.4 1e-05 25.4 8.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF3337 PF11816.8 KDO25499.1 - 6e-06 26.2 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) zf-C3HC4_3 PF13920.6 KDO25499.1 - 8.3e-06 25.6 6.3 1.4e-05 24.9 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO25499.1 - 8.9e-06 25.9 9.0 1.6e-05 25.1 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 KDO25499.1 - 0.0013 18.6 1.7 0.002 17.9 1.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KDO25499.1 - 0.012 15.5 5.4 0.025 14.4 5.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO25499.1 - 0.013 15.4 12.4 0.13 12.1 10.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KDO25499.1 - 0.02 15.0 6.8 0.049 13.8 6.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KDO25499.1 - 0.032 14.1 2.9 0.041 13.7 2.1 1.6 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Siva PF05458.12 KDO25499.1 - 0.079 12.6 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-rbx1 PF12678.7 KDO25499.1 - 0.22 11.8 8.3 0.43 10.9 8.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KDO25499.1 - 1.2 9.0 6.9 4.7 7.1 7.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KDO25499.1 - 2.8 7.7 9.5 4.8 6.9 8.7 1.9 1 1 0 1 1 1 0 P-11 zinc finger Trypsin PF00089.26 KDO25500.1 - 2.8e-52 177.7 1.4 3.2e-52 177.5 1.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KDO25500.1 - 2.3e-06 28.6 0.3 4.8e-06 27.5 0.3 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO25501.1 - 3.6e-44 151.2 1.6 1.3e-42 146.1 1.6 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KDO25501.1 - 1.8e-06 28.9 0.5 3.1e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO25502.1 - 6.7e-47 160.1 0.2 7.7e-47 159.9 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KDO25502.1 - 0.00011 23.2 0.4 0.00028 21.8 0.3 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Sensor PF13796.6 KDO25503.1 - 2.9e-09 37.2 14.9 4.2e-09 36.7 14.9 1.3 1 0 0 1 1 1 1 Putative sensor eIF-6 PF01912.18 KDO25504.1 - 3.7e-81 271.2 1.2 3.7e-81 271.2 1.2 1.4 2 0 0 2 2 2 1 eIF-6 family B56 PF01603.20 KDO25505.1 - 2.1e-91 307.0 0.5 2.7e-89 300.1 0.5 2.0 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Lipase3_N PF03893.16 KDO25505.1 - 0.0051 16.8 0.2 0.025 14.6 0.1 2.2 3 0 0 3 3 3 1 Lipase 3 N-terminal region DUF1765 PF08578.10 KDO25505.1 - 0.012 16.0 1.4 0.024 15.1 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) CxC4 PF18717.1 KDO25505.1 - 0.027 14.3 1.3 0.043 13.6 0.4 1.8 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases FAD_binding_1 PF00667.20 KDO25506.1 - 3.7e-19 69.2 0.0 5.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KDO25506.1 - 1.5e-17 64.1 0.1 3.1e-17 63.1 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KDO25506.1 - 8e-14 52.2 0.1 1.3e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KDO25506.1 - 0.046 13.8 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Cation_ATPase_C PF00689.21 KDO25507.1 - 7.6e-44 149.6 3.2 2.1e-43 148.2 3.2 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO25507.1 - 3.6e-30 104.8 7.7 2.9e-20 72.5 0.1 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KDO25507.1 - 9.9e-15 55.4 0.2 7.7e-14 52.5 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO25507.1 - 1.6e-14 53.8 0.0 3.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KDO25507.1 - 5.3e-12 45.3 0.0 1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO25507.1 - 0.00041 20.2 0.2 0.003 17.3 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ish1 PF10281.9 KDO25507.1 - 0.17 12.2 0.1 4.5 7.7 0.2 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ricin_B_lectin PF00652.22 KDO25508.1 - 7.4e-13 48.9 4.8 1.5e-06 28.5 0.5 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain SAM_1 PF00536.30 KDO25508.1 - 0.0018 18.7 0.1 0.0032 17.9 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCHC_6 PF15288.6 KDO25508.1 - 0.39 10.6 4.7 35 4.3 0.2 3.7 3 0 0 3 3 3 0 Zinc knuckle TIR_2 PF13676.6 KDO25509.1 - 1.1e-11 45.3 0.0 2.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ricin_B_lectin PF00652.22 KDO25509.1 - 3.7e-11 43.4 5.5 4.3e-05 23.8 0.5 3.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain SAM_1 PF00536.30 KDO25509.1 - 1.2e-05 25.7 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO25509.1 - 4e-05 23.7 0.0 9.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TIR PF01582.20 KDO25509.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 TIR domain RAD51_interact PF15696.5 KDO25509.1 - 0.68 10.1 4.7 0.45 10.6 0.3 2.7 3 0 0 3 3 3 0 RAD51 interacting motif RicinB_lectin_2 PF14200.6 KDO25510.1 - 5.2e-06 27.1 0.1 0.0053 17.5 0.0 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Oxidored_molyb PF00174.19 KDO25511.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 1 0 1 1 1 0 Oxidoreductase molybdopterin binding domain CorA PF01544.18 KDO25513.1 - 1.4e-33 116.5 1.6 8.4e-25 87.7 0.1 3.2 1 1 1 3 3 3 3 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 KDO25513.1 - 0.0034 17.8 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF2207 PF09972.9 KDO25513.1 - 0.012 14.4 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PsbR PF04725.12 KDO25514.1 - 0.0064 16.8 0.0 0.0079 16.5 0.0 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR zf-H2C2_2 PF13465.6 KDO25515.1 - 4.7e-22 77.4 18.4 9.8e-09 35.3 0.1 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KDO25515.1 - 1.6e-21 75.4 17.6 1.5e-05 25.2 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO25515.1 - 3e-14 52.5 21.0 0.0011 19.6 0.3 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 KDO25515.1 - 3.8e-12 46.2 5.4 0.0042 17.4 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KDO25515.1 - 6.6e-09 35.8 4.1 0.00059 20.1 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KDO25515.1 - 1.2e-06 28.4 8.7 0.0017 18.3 0.1 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KDO25515.1 - 0.0015 18.3 7.6 0.21 11.4 0.1 4.1 4 0 0 4 4 4 2 C2H2-type zinc-finger domain BolA PF01722.18 KDO25515.1 - 0.01 16.1 6.3 1.1 9.6 0.0 3.8 1 1 4 5 5 5 0 BolA-like protein zf_UBZ PF18439.1 KDO25515.1 - 0.17 11.5 3.6 12 5.5 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KDO25515.1 - 0.27 10.9 4.8 10 5.9 0.7 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_4 PF07975.12 KDO25515.1 - 0.45 10.8 13.2 1.4 9.2 0.6 3.6 2 1 1 4 4 4 0 TFIIH C1-like domain Actin_micro PF17003.5 KDO25515.1 - 1.8 7.7 3.8 5.9 6.0 3.8 1.9 1 1 0 1 1 1 0 Putative actin-like family Zf_RING PF16744.5 KDO25515.1 - 1.9 8.6 9.6 2.6 8.2 0.1 3.8 2 1 3 5 5 5 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KDO25515.1 - 1.9 8.8 13.7 2.3 8.6 0.3 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.32 KDO25516.1 - 1.7e-30 104.6 10.6 6.2e-08 33.2 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25516.1 - 5.5e-10 39.4 0.0 0.013 15.8 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO25516.1 - 1.2e-05 25.2 0.1 0.045 13.6 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KDO25516.1 - 0.047 13.3 0.1 0.48 10.0 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KDO25516.1 - 0.16 10.6 0.4 2.1 6.9 0.0 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 TPR_8 PF13181.6 KDO25518.1 - 1.3e-18 65.6 19.9 9.7e-06 25.4 0.0 8.0 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25518.1 - 3.4e-17 61.5 25.8 1.9e-06 27.5 0.0 7.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25518.1 - 8.4e-13 47.4 30.9 0.00015 21.6 0.0 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25518.1 - 2.4e-12 46.3 8.5 3.6e-07 29.8 2.0 4.4 3 1 1 4 4 4 3 TPR repeat ANAPC8 PF04049.13 KDO25518.1 - 6.2e-12 45.7 2.6 5.5e-10 39.4 0.7 3.0 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_16 PF13432.6 KDO25518.1 - 1.4e-11 44.8 37.0 9.2e-06 26.2 2.9 8.2 7 3 2 9 9 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25518.1 - 1.3e-10 41.2 32.5 9.4e-05 22.9 0.2 8.9 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25518.1 - 9.4e-09 35.7 20.5 0.02 15.4 0.3 8.1 6 3 3 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25518.1 - 1.6e-07 30.8 18.8 0.0045 16.9 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25518.1 - 3.9e-07 30.2 14.3 0.032 14.4 0.2 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KDO25518.1 - 4.9e-06 26.5 11.9 0.12 12.8 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO25518.1 - 0.0023 18.4 19.2 0.44 11.3 0.3 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25518.1 - 0.003 17.8 23.5 0.19 12.0 0.0 6.5 5 1 1 7 7 6 2 Tetratricopeptide repeat DUF3808 PF10300.9 KDO25518.1 - 0.0093 14.7 0.2 0.071 11.8 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_15 PF13429.6 KDO25518.1 - 0.016 14.4 6.2 0.062 12.5 3.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 KDO25518.1 - 0.28 10.0 4.1 0.8 8.5 0.4 2.9 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 KDO25518.1 - 0.32 11.2 24.9 0.17 12.1 0.3 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Fz PF01392.22 KDO25520.1 - 2e-06 28.4 2.8 3.7e-06 27.5 2.8 1.6 1 1 0 1 1 1 1 Fz domain Mid1 PF12929.7 KDO25520.1 - 0.046 12.9 3.4 0.062 12.5 3.4 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component hNIFK_binding PF12196.8 KDO25520.1 - 0.12 11.8 0.2 0.28 10.7 0.2 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK TCR PF03638.15 KDO25521.1 - 0.0033 17.7 18.3 0.0033 17.7 18.3 3.4 4 1 0 4 4 4 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Ank_2 PF12796.7 KDO25523.1 - 2e-10 41.1 3.4 0.0034 17.9 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO25523.1 - 4.4e-08 33.2 6.1 0.22 11.9 0.1 5.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25523.1 - 5e-08 33.3 9.1 0.014 16.0 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25523.1 - 0.00054 20.2 4.5 1.1e+02 3.9 0.0 6.9 6 2 2 8 8 8 0 Ankyrin repeat Ank PF00023.30 KDO25523.1 - 0.053 14.0 0.1 22 5.7 0.1 4.0 1 1 0 1 1 1 0 Ankyrin repeat DBD_Tnp_Mut PF03108.15 KDO25524.1 - 0.00098 19.1 3.0 0.0013 18.7 0.9 2.1 2 0 0 2 2 2 1 MuDR family transposase FYVE PF01363.21 KDO25525.1 - 5.9e-07 29.5 5.0 1.1e-06 28.7 5.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO25525.1 - 0.00054 20.6 0.1 0.0015 19.2 0.0 1.7 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO25525.1 - 1.2 9.3 8.6 2.2 8.5 8.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PK PF00224.21 KDO25526.1 - 2.9e-109 365.2 2.9 4e-109 364.7 2.9 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KDO25526.1 - 1.2e-17 64.2 0.0 4.5e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KDO25526.1 - 0.0019 17.4 0.7 0.0062 15.7 0.1 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family zf-C3HC4_3 PF13920.6 KDO25528.1 - 6.9e-05 22.6 7.9 0.00011 22.0 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO25528.1 - 0.0013 19.1 11.2 0.0025 18.1 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KDO25528.1 - 0.011 15.8 10.7 0.023 14.9 10.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING APOBEC4_like PF18774.1 KDO25528.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase zf-RING_14 PF17978.1 KDO25528.1 - 0.089 13.2 1.7 0.15 12.5 1.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KDO25528.1 - 0.62 10.0 14.1 0.31 10.9 12.0 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO25528.1 - 0.68 9.8 12.7 5.6 6.9 12.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO25528.1 - 1.6 8.7 11.1 3.2 7.7 11.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Selenoprotein_S PF06936.11 KDO25529.1 - 2.2e-06 27.6 3.7 1.9e-05 24.6 0.5 2.0 1 1 1 2 2 2 2 Selenoprotein S (SelS) Lys_export PF03956.13 KDO25529.1 - 0.22 11.0 1.3 0.27 10.8 1.3 1.1 1 0 0 1 1 1 0 Lysine exporter LysO RCC1 PF00415.18 KDO25530.1 - 3.2e-88 290.2 21.5 1.1e-17 64.4 0.6 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO25530.1 - 2.4e-47 157.8 37.6 2.5e-12 46.3 0.8 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat MliC PF09864.9 KDO25530.1 - 0.013 15.4 0.8 0.93 9.5 0.1 3.5 3 0 0 3 3 3 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Kelch_5 PF13854.6 KDO25530.1 - 0.17 12.0 2.5 13 5.9 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Hira PF07569.11 KDO25530.1 - 0.17 11.6 0.8 16 5.1 0.0 3.9 6 0 0 6 6 6 0 TUP1-like enhancer of split C2 PF00168.30 KDO25531.1 - 7.1e-13 48.7 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_Tyr PF07714.17 KDO25531.1 - 7.7e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO25531.1 - 2.9e-09 36.7 0.0 4.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain 3-HAO PF06052.12 KDO25531.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase ATP-grasp_5 PF13549.6 KDO25532.1 - 0.0068 15.9 0.0 0.23 10.9 0.0 2.6 2 2 0 2 2 2 1 ATP-grasp domain F-box-like_2 PF13013.6 KDO25532.1 - 0.036 14.0 3.8 0.15 12.0 0.1 3.3 3 1 0 3 3 3 0 F-box-like domain C2 PF00168.30 KDO25534.1 - 3.7e-12 46.4 0.0 4.1e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 C2 domain IQ PF00612.27 KDO25535.1 - 0.0018 17.9 8.1 0.16 11.8 0.7 3.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif EF-hand_6 PF13405.6 KDO25535.1 - 0.0057 16.5 0.1 0.019 14.9 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KDO25535.1 - 0.064 12.8 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 EF hand PAF-AH_p_II PF03403.13 KDO25536.1 - 0.91 8.0 2.6 1.3 7.5 2.6 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Mannosyl_trans3 PF11051.8 KDO25538.1 - 5.5e-31 107.9 0.0 7.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative CKS PF01111.19 KDO25538.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit IspD PF01128.19 KDO25538.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MAPEG PF01124.18 KDO25539.1 - 1.8e-16 60.2 0.9 2.3e-16 59.9 0.9 1.2 1 0 0 1 1 1 1 MAPEG family GlcNAc PF11397.8 KDO25540.1 - 2e-45 155.8 3.3 1.1e-36 127.0 3.1 2.4 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) UBX PF00789.20 KDO25540.1 - 0.002 18.3 0.9 1.6 9.0 0.1 2.6 1 1 1 2 2 2 2 UBX domain TMEM206 PF15122.6 KDO25540.1 - 0.028 13.6 0.1 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 TMEM206 protein family MCPsignal PF00015.21 KDO25540.1 - 0.15 11.8 6.8 0.092 12.6 1.7 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HAND PF09110.11 KDO25540.1 - 0.51 11.1 3.6 3.9 8.3 3.4 2.1 1 1 1 2 2 2 0 HAND FGGY_N PF00370.21 KDO25541.1 - 9.4e-72 241.5 0.2 1.3e-71 241.0 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KDO25541.1 - 5.8e-63 212.2 1.3 8.7e-63 211.6 1.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KDO25541.1 - 0.0014 18.2 0.6 0.15 11.6 0.0 2.7 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Phage_lysozyme2 PF18013.1 KDO25542.1 - 0.069 13.2 1.2 0.1 12.6 1.2 1.2 1 0 0 1 1 1 0 Phage tail lysozyme Myb_DNA-bind_2 PF08914.11 KDO25542.1 - 8.1 6.7 8.9 0.73 10.1 0.6 2.7 3 1 0 3 3 3 0 Rap1 Myb domain Biopterin_H PF00351.21 KDO25543.1 - 1.6e-141 471.2 0.1 2e-141 470.8 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KDO25543.1 - 4.1e-05 23.3 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain PTR2 PF00854.21 KDO25544.1 - 2.9e-58 197.6 7.4 4.6e-58 196.9 7.4 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KDO25544.1 - 1.1e-08 34.4 13.0 1.1e-08 34.4 13.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4293 PF14126.6 KDO25544.1 - 0.0068 16.7 0.9 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) DUF3980 PF13140.6 KDO25544.1 - 0.037 14.5 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) DUF2418 PF10332.9 KDO25544.1 - 0.12 12.9 0.0 0.77 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF1772 PF08592.11 KDO25544.1 - 8.5 6.7 14.1 4.5 7.6 0.1 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF1772) Nucleoporin_N PF08801.11 KDO25545.1 - 4.6e-50 170.6 0.0 1.4e-49 169.0 0.0 1.8 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KDO25545.1 - 1.9e-09 36.9 0.3 2.9e-09 36.2 0.3 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Mtc PF03820.17 KDO25546.1 - 3.5e-131 436.9 0.2 3.9e-131 436.7 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ufm1 PF03671.14 KDO25547.1 - 1.2e-41 140.6 0.1 2.4e-41 139.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Ricin_B_lectin PF00652.22 KDO25547.1 - 2.9e-15 56.6 7.7 0.00041 20.6 0.1 3.3 3 0 0 3 3 3 3 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 KDO25548.1 - 6.2e-15 55.6 11.4 0.00042 20.6 3.0 4.6 3 2 1 4 4 4 4 Ricin-type beta-trefoil lectin domain zf-MYND PF01753.18 KDO25549.1 - 0.00051 20.1 11.3 0.00051 20.1 11.3 2.1 2 0 0 2 2 2 1 MYND finger SET PF00856.28 KDO25549.1 - 0.00071 20.0 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 SET domain PTR2 PF00854.21 KDO25551.1 - 1.2e-60 205.4 11.0 4.2e-60 203.7 11.0 1.7 1 1 0 1 1 1 1 POT family Oxidored_q2 PF00420.24 KDO25551.1 - 5.3 6.7 9.4 4.3 7.0 0.3 3.8 4 0 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF996 PF06195.13 KDO25551.1 - 6.9 7.0 15.9 1.4 9.2 1.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF996) Abhydrolase_3 PF07859.13 KDO25553.1 - 2.4e-22 79.8 0.0 3.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO25553.1 - 2.2e-08 33.8 0.1 2.1e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO25553.1 - 0.00012 21.5 0.0 0.0051 16.1 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO25553.1 - 0.00017 22.2 0.9 0.00017 22.2 0.9 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 KDO25553.1 - 0.00049 19.1 0.0 0.00092 18.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KDO25553.1 - 0.024 13.5 0.0 0.059 12.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KDO25553.1 - 0.072 12.9 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 KDO25553.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.8 KDO25553.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LIP PF03583.14 KDO25553.1 - 0.19 11.0 0.0 0.56 9.5 0.0 1.8 1 0 0 1 1 1 0 Secretory lipase Lar_restr_allev PF14354.6 KDO25554.1 - 0.0011 19.3 3.3 0.022 15.1 0.3 2.8 2 0 0 2 2 2 1 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.12 KDO25554.1 - 0.012 15.9 3.1 0.14 12.4 0.1 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DUF2752 PF10825.8 KDO25554.1 - 0.045 13.8 4.4 0.65 10.1 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-Mss51 PF13824.6 KDO25554.1 - 0.058 13.5 2.0 1.8 8.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.10 KDO25554.1 - 0.12 12.5 5.1 2.1 8.5 0.2 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-RRN7 PF11781.8 KDO25554.1 - 0.13 12.0 1.9 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ogr_Delta PF04606.12 KDO25554.1 - 0.41 10.7 6.3 4.4 7.3 1.0 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF1451 PF07295.11 KDO25554.1 - 1 9.4 2.5 1.7 8.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain Ribosomal_L32p PF01783.23 KDO25554.1 - 1.8 8.9 7.7 14 6.0 0.2 3.4 3 0 0 3 3 3 0 Ribosomal L32p protein family PARP PF00644.20 KDO25555.1 - 2.3e-15 56.7 0.0 3.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LRR_4 PF12799.7 KDO25556.1 - 0.12 12.9 0.6 2.2 8.8 0.0 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) zf-BED PF02892.15 KDO25557.1 - 0.077 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 BED zinc finger BUD22 PF09073.10 KDO25558.1 - 0.65 9.3 22.4 1 8.6 22.4 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KDO25558.1 - 4.4 5.4 28.3 1.3 7.1 25.4 1.5 2 0 0 2 2 2 0 Nop14-like family Phage_integrase PF00589.22 KDO25559.1 - 0.00029 20.7 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family NAGLU PF05089.12 KDO25562.1 - 1.3e-125 418.8 4.9 1.8e-125 418.3 4.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KDO25562.1 - 3.9e-64 216.8 2.9 6.6e-64 216.0 2.9 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KDO25562.1 - 2e-15 56.3 0.0 7.7e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Retrotrans_gag PF03732.17 KDO25563.1 - 2e-06 28.0 4.2 0.00015 21.9 0.3 2.7 2 1 1 3 3 3 2 Retrotransposon gag protein zf-CCHC_2 PF13696.6 KDO25563.1 - 1.9e-05 24.4 6.9 3.4e-05 23.5 6.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KDO25563.1 - 0.002 18.1 5.9 0.002 18.1 5.9 2.8 3 0 0 3 3 3 1 Zinc knuckle Ribonuc_red_lgN PF00317.21 KDO25563.1 - 0.015 15.3 0.7 5 7.2 0.0 2.9 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain SLATT_4 PF18186.1 KDO25563.1 - 0.028 14.1 0.2 0.075 12.7 0.2 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Trypsin PF00089.26 KDO25564.1 - 2.1e-46 158.5 0.1 2.5e-46 158.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KDO25565.1 - 7.9e-47 159.9 0.2 9.2e-47 159.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KDO25566.1 - 7.9e-47 159.9 0.2 9.2e-47 159.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin 60KD_IMP PF02096.20 KDO25568.1 - 5e-34 117.6 2.3 6.6e-34 117.2 2.3 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3464 PF11947.8 KDO25568.1 - 1.1 8.9 4.5 1.2 8.8 0.2 2.8 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 DUF5326 PF17260.2 KDO25568.1 - 3 8.1 5.8 0.7 10.1 1.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Ricin_B_lectin PF00652.22 KDO25569.1 - 2.6e-29 102.1 26.5 1e-11 45.2 6.6 2.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain PT PF04886.12 KDO25569.1 - 2.6e-21 74.8 113.9 2.5e-07 30.1 17.4 6.7 3 2 1 4 4 4 3 PT repeat RicinB_lectin_2 PF14200.6 KDO25569.1 - 6.8e-10 39.5 9.9 0.0019 18.9 0.4 4.0 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO25569.1 - 8.6e-06 25.4 10.7 0.0042 16.7 0.5 3.2 1 1 1 3 3 3 2 Cytolethal distending toxin A/C domain Isochorismatase PF00857.20 KDO25570.1 - 3.6e-27 95.7 0.0 5.1e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family ROQ_II PF18386.1 KDO25570.1 - 0.024 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Roquin II domain BT1 PF03092.16 KDO25572.1 - 5.2e-08 31.6 2.5 5.2e-08 31.6 2.5 3.3 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO25572.1 - 0.0018 17.3 0.6 0.0018 17.3 0.6 2.4 2 0 0 2 2 2 1 PUCC protein p450 PF00067.22 KDO25574.1 - 7.1e-21 74.5 0.0 2.6e-14 52.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Metallophos PF00149.28 KDO25575.1 - 0.00021 21.8 0.2 0.00065 20.2 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KDO25576.1 - 5.4e-07 30.3 0.0 1.5e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CwsA PF10814.8 KDO25576.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA CBAH PF02275.18 KDO25577.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Metallophos PF00149.28 KDO25578.1 - 2.1e-09 38.2 0.1 1e-08 36.0 0.1 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KDO25579.1 - 9.4e-07 29.5 1.5 6.1e-06 26.9 1.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KDO25580.1 - 6.5e-07 30.1 0.2 1.3e-06 29.1 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ETRAMP PF09716.10 KDO25580.1 - 0.006 16.6 1.5 0.011 15.8 0.5 2.0 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF3552 PF12072.8 KDO25580.1 - 0.22 10.9 0.1 0.36 10.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4448 PF14610.6 KDO25580.1 - 0.53 10.0 4.7 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Metallophos PF00149.28 KDO25581.1 - 1.2e-08 35.7 0.5 6.8e-08 33.2 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAN_4 PF14295.6 KDO25583.1 - 2.8e-22 78.4 51.5 1.7e-08 34.2 4.0 6.8 7 0 0 7 7 7 4 PAN domain PAN_1 PF00024.26 KDO25583.1 - 5e-15 55.2 26.5 0.00011 22.1 0.1 7.5 8 0 0 8 8 8 5 PAN domain PIG-L PF02585.17 KDO25583.1 - 8.1e-10 39.4 0.1 1.8e-09 38.3 0.1 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_3 PF08277.12 KDO25583.1 - 0.041 13.7 26.3 0.052 13.4 3.4 4.8 4 0 0 4 4 4 0 PAN-like domain Ank_2 PF12796.7 KDO25584.1 - 3e-14 53.4 10.6 1.3e-06 28.9 1.0 3.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25584.1 - 4.1e-14 52.7 13.3 5.9e-05 23.5 0.2 5.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25584.1 - 1.8e-08 33.9 7.6 0.69 10.7 0.1 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KDO25584.1 - 4.4e-05 23.7 14.5 1.8 9.0 0.1 6.5 3 1 4 7 7 7 3 Ankyrin repeats (many copies) SSXT PF05030.12 KDO25585.1 - 1.3e-16 60.0 0.5 2.7e-16 58.9 0.5 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) HA PF03457.14 KDO25586.1 - 3.9e-34 116.8 0.0 2.8e-07 30.8 0.0 6.2 6 0 0 6 6 6 5 Helicase associated domain HEAT PF02985.22 KDO25586.1 - 0.16 12.3 0.0 10 6.7 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Ephrin_rec_like PF07699.13 KDO25587.1 - 3.4e-05 23.5 3.4 3.4e-05 23.5 3.4 13.8 9 6 4 13 13 13 2 Putative ephrin-receptor like DUF1776 PF08643.10 KDO25587.1 - 0.3 10.4 0.0 0.47 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4684 PF15736.5 KDO25587.1 - 1.2 7.7 3.2 1.9 7.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Ion_trans PF00520.31 KDO25588.1 - 1.1e-35 123.0 29.8 2e-20 73.1 16.2 2.4 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 KDO25588.1 - 1.4e-24 86.0 0.0 6.1e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO25588.1 - 2.4e-13 49.9 26.0 3.2e-09 36.6 10.4 3.6 4 0 0 4 4 4 2 Ion channel UPF0542 PF15086.6 KDO25588.1 - 0.033 14.1 0.4 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 XRCC4 PF06632.12 KDO25588.1 - 0.066 12.1 0.3 9.9 4.9 0.0 2.4 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pox_A9 PF04835.12 KDO25588.1 - 0.66 10.2 3.3 23 5.2 0.2 2.7 2 0 0 2 2 2 0 A9 protein conserved region Mito_carr PF00153.27 KDO25589.1 - 7.4e-75 247.0 1.7 1.3e-24 86.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.16 KDO25590.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 Frataxin-like domain Pkinase PF00069.25 KDO25592.1 - 1.4e-39 136.1 0.0 1.9e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25592.1 - 4.4e-17 62.2 0.0 6.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO25592.1 - 5.3e-07 29.2 0.1 1.3e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO25592.1 - 4.5e-06 26.8 0.7 4e-05 23.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO25592.1 - 3.7e-05 23.2 0.0 8.9e-05 21.9 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Peptidase_C92 PF05708.12 KDO25594.1 - 2.6e-06 27.6 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family ABC_tran PF00005.27 KDO25598.1 - 2.1e-27 96.3 0.0 3.5e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO25598.1 - 9.4e-23 81.2 10.9 1.7e-22 80.4 10.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO25598.1 - 7.2e-07 28.9 0.1 3e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO25598.1 - 8.2e-05 22.9 0.0 0.00041 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KDO25598.1 - 0.00074 19.5 0.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KDO25598.1 - 0.0011 19.3 0.1 0.0032 17.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KDO25598.1 - 0.0064 16.6 0.1 0.02 15.0 0.0 1.9 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KDO25598.1 - 0.0069 16.1 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KDO25598.1 - 0.0085 16.5 0.0 0.094 13.1 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KDO25598.1 - 0.0099 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 KDO25598.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CG-1 PF03859.16 KDO25598.1 - 0.036 13.9 0.1 0.071 12.9 0.1 1.4 1 0 0 1 1 1 0 CG-1 domain AAA_5 PF07728.14 KDO25598.1 - 0.051 13.6 0.1 0.49 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KDO25598.1 - 0.057 12.8 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KDO25598.1 - 0.076 12.8 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO25598.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Guanylate_kin PF00625.21 KDO25598.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase Septin PF00735.18 KDO25598.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 KDO25598.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KDO25598.1 - 0.12 12.7 1.8 0.21 11.9 0.1 2.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KDO25598.1 - 0.16 12.4 0.0 0.47 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase CHAP PF05257.16 KDO25599.1 - 1.5e-13 51.2 0.1 2.4e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 CHAP domain Ank_2 PF12796.7 KDO25600.1 - 1.3e-19 70.6 22.7 4.7e-06 27.1 0.7 5.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25600.1 - 9.4e-18 64.3 22.7 8.8e-06 26.2 0.3 7.1 5 3 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO25600.1 - 1.4e-14 53.9 19.3 0.0051 17.1 0.2 9.5 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25600.1 - 1.7e-09 37.1 16.3 1.4 9.7 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 KDO25600.1 - 0.058 13.9 20.8 12 6.6 0.0 7.5 4 2 2 6 6 6 0 Ankyrin repeat HA PF03457.14 KDO25602.1 - 7.5e-34 115.9 0.0 1.3e-07 31.8 0.0 9.5 11 0 0 11 11 11 7 Helicase associated domain p450 PF00067.22 KDO25603.1 - 1.1e-27 96.9 0.0 6.9e-27 94.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 HA PF03457.14 KDO25604.1 - 2.8e-22 78.8 2.5 1.8e-07 31.4 0.0 4.2 4 0 0 4 4 4 3 Helicase associated domain SBP_bac_11 PF13531.6 KDO25604.1 - 0.094 12.4 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cation_efflux PF01545.21 KDO25605.1 - 6.4e-40 137.0 9.0 8.2e-40 136.7 9.0 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5362 PF17319.2 KDO25605.1 - 0.0092 15.8 0.4 0.023 14.5 0.2 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5362) SelP_N PF04592.14 KDO25605.1 - 0.61 9.5 5.2 0.91 8.9 5.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cation_efflux PF01545.21 KDO25606.1 - 6.2e-47 159.9 4.7 7.5e-47 159.6 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 KDO25606.1 - 0.023 13.9 17.2 0.0069 15.7 14.1 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter DUF5362 PF17319.2 KDO25606.1 - 0.052 13.4 2.5 0.088 12.7 1.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5362) HMG-CoA_red PF00368.18 KDO25606.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Phage_holin_1 PF04531.13 KDO25606.1 - 5 7.7 5.5 12 6.5 0.2 3.2 2 1 2 4 4 4 0 Bacteriophage holin BTB_2 PF02214.22 KDO25607.1 - 1.9e-11 44.2 0.0 3.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TUDOR_5 PF18359.1 KDO25608.1 - 1.2e-50 169.0 52.9 2.1e-07 30.5 0.7 10.6 10 1 1 11 11 10 9 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 KDO25608.1 - 3.3e-28 97.3 15.2 0.0085 15.9 0.2 8.9 8 1 1 9 9 8 7 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 KDO25608.1 - 6.6e-27 93.8 26.9 0.002 18.5 0.0 10.9 10 1 1 11 11 11 9 Agenet domain DUF1325 PF07039.11 KDO25608.1 - 2.4e-21 76.2 23.9 0.066 13.3 0.1 8.5 5 3 3 8 8 8 8 SGF29 tudor-like domain DUF4537 PF15057.6 KDO25608.1 - 2.4e-17 63.1 10.3 0.059 13.4 0.1 8.5 5 2 2 7 7 7 6 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 KDO25608.1 - 8.7e-12 45.1 23.9 0.0013 18.6 0.2 8.4 7 1 1 8 8 8 4 Tumour suppressor p53-binding protein-1 Tudor LBR_tudor PF09465.10 KDO25608.1 - 5.2e-08 32.6 36.3 0.42 10.5 0.4 8.8 8 1 1 9 9 9 5 Lamin-B receptor of TUDOR domain SR-25 PF10500.9 KDO25608.1 - 5.7e-08 32.6 13.8 5.7e-08 32.6 13.8 3.8 4 0 0 4 4 2 1 Nuclear RNA-splicing-associated protein TUDOR PF00567.24 KDO25608.1 - 0.00032 20.7 2.7 2.4 8.2 0.0 5.7 6 2 2 8 8 8 1 Tudor domain Macoilin PF09726.9 KDO25608.1 - 0.061 11.9 2.7 0.11 11.1 2.7 1.3 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 KDO25608.1 - 0.11 10.4 0.3 0.21 9.4 0.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RanBP PF00641.18 KDO25608.1 - 0.31 10.4 13.5 1.6 8.1 2.1 2.5 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KDO25608.1 - 0.41 10.7 9.2 0.74 9.9 1.4 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger CxC3 PF18804.1 KDO25608.1 - 0.51 10.2 3.8 1 9.2 3.8 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases DZR PF12773.7 KDO25608.1 - 2.4 8.3 7.5 0.32 11.1 1.5 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF4614 PF15391.6 KDO25608.1 - 3.7 7.5 13.0 11 5.9 13.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) FKBP_C PF00254.28 KDO25608.1 - 5.7 7.3 16.7 30 5.0 0.4 6.5 5 4 2 7 7 7 0 FKBP-type peptidyl-prolyl cis-trans isomerase Ribonuclease_3 PF00636.26 KDO25609.1 - 3.4e-09 37.3 0.0 5.3e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KDO25609.1 - 1.8e-08 34.6 0.1 2.7e-06 27.6 0.0 2.5 2 1 0 2 2 2 2 Ribonuclease-III-like PAZ PF02170.22 KDO25609.1 - 0.00014 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Ank_2 PF12796.7 KDO25610.1 - 1.3e-11 44.9 0.1 3.4e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25610.1 - 2.4e-08 34.4 4.3 2.8e-05 24.6 1.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25610.1 - 8.8e-08 31.8 0.7 0.065 13.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO25610.1 - 1.2e-07 31.8 2.2 0.0039 17.5 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO25610.1 - 0.0075 16.7 2.1 0.48 11.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat zf-H2C2_2 PF13465.6 KDO25610.1 - 1.2 9.7 3.5 0.73 10.4 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger double domain Cas_csx3 PF09620.10 KDO25611.1 - 0.047 13.6 0.4 0.15 12.0 0.4 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) ABC2_membrane_2 PF12679.7 KDO25611.1 - 0.28 10.4 6.5 0.076 12.3 0.8 2.4 1 1 1 2 2 2 0 ABC-2 family transporter protein zf-CCCH_4 PF18044.1 KDO25612.1 - 0.18 11.7 0.2 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Mito_carr PF00153.27 KDO25613.1 - 2.1e-53 178.2 3.2 7.8e-18 64.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FYVE PF01363.21 KDO25614.1 - 5.6e-11 42.4 13.4 1.3e-10 41.3 13.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO25614.1 - 4.8e-09 35.9 0.2 8.3e-09 35.2 0.2 1.3 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO25614.1 - 8.5e-05 22.8 7.1 0.00018 21.7 7.1 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 KDO25614.1 - 0.008 16.5 3.3 0.008 16.5 3.3 1.9 2 0 0 2 2 2 1 C1 domain UPF0515 PF15135.6 KDO25614.1 - 0.029 13.7 4.6 0.057 12.8 4.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 IBR PF01485.21 KDO25614.1 - 0.54 10.5 7.8 0.21 11.8 3.3 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KDO25615.1 - 9e-11 41.8 3.1 1.5e-10 41.1 3.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 KDO25616.1 - 0.00055 20.0 14.8 0.0015 18.6 14.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO25616.1 - 0.053 13.7 7.2 0.11 12.7 7.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 KDO25616.1 - 0.23 11.7 10.2 0.74 10.1 10.2 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Siva PF05458.12 KDO25616.1 - 0.58 9.8 7.9 1 9.0 7.9 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_5 PF14634.6 KDO25616.1 - 1.3 9.1 16.0 0.53 10.3 12.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KDO25616.1 - 1.9 8.7 9.8 1.1 9.5 3.2 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO25616.1 - 2.1 8.2 8.5 8.1 6.3 8.5 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KDO25616.1 - 7.6 7.0 11.8 24 5.4 11.8 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KDO25616.1 - 9.8 6.1 13.4 1.6e+02 2.3 13.5 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA PF00004.29 KDO25618.1 - 3.1e-40 137.7 0.0 1.1e-39 135.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO25618.1 - 2.3e-09 36.9 0.0 5.3e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KDO25618.1 - 5.5e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KDO25618.1 - 7.5e-05 22.8 0.1 0.00045 20.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO25618.1 - 0.0011 19.4 0.1 0.0066 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO25618.1 - 0.0015 18.8 0.0 0.0075 16.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KDO25618.1 - 0.0056 15.9 0.0 0.0096 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KDO25618.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KDO25618.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO25618.1 - 0.027 14.2 0.1 0.18 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO25618.1 - 0.028 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO25618.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO25618.1 - 0.038 13.5 0.0 0.096 12.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO25618.1 - 0.053 13.9 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KDO25618.1 - 0.087 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KDO25618.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ApbA_C PF08546.11 KDO25619.1 - 3.2e-27 95.2 0.0 4.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KDO25619.1 - 1.2e-21 76.9 0.2 1.9e-21 76.3 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KDO25619.1 - 0.015 15.9 2.1 0.46 11.1 2.1 3.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Myb_DNA-binding PF00249.31 KDO25620.1 - 2.7e-29 101.1 1.4 3.3e-15 56.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO25620.1 - 1.3e-19 70.2 0.5 9.6e-14 51.4 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO25620.1 - 1.7e-08 34.2 0.8 0.00032 20.5 0.1 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 KDO25620.1 - 0.012 15.6 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 SLIDE Trypsin PF00089.26 KDO25621.1 - 9.2e-25 87.8 0.2 1.1e-24 87.5 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KDO25621.1 - 1.1e-05 26.4 0.5 1.5e-05 26.0 0.5 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KDO25621.1 - 0.037 13.6 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 KDO25622.1 - 1.2e-30 107.0 0.1 1.4e-30 106.8 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KDO25622.1 - 2.9e-07 31.5 0.0 4.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KDO25622.1 - 0.003 17.2 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Peptidase_C2 PF00648.21 KDO25624.1 - 1.4e-51 175.3 0.1 2.2e-51 174.7 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KDO25624.1 - 2.2e-28 99.3 0.0 2.4e-12 47.3 0.0 4.2 4 0 0 4 4 4 3 Calpain large subunit, domain III WW PF00397.26 KDO25626.1 - 1.1e-21 76.5 16.5 3.5e-12 46.2 3.3 2.3 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KDO25626.1 - 0.44 10.9 8.6 2.9 8.2 1.6 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Voltage_CLC PF00654.20 KDO25627.1 - 4.7e-81 272.8 22.0 1.2e-80 271.4 20.7 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KDO25627.1 - 2.6e-09 37.4 1.5 8.7e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 CBS domain SieB PF14163.6 KDO25627.1 - 0.021 14.3 0.7 0.13 11.7 0.2 2.6 3 0 0 3 3 3 0 Super-infection exclusion protein B TAT_signal PF10518.9 KDO25627.1 - 5.2 7.1 8.3 1.1 9.2 2.3 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence MFS_MOT1 PF16983.5 KDO25627.1 - 6.1 7.3 13.4 0.17 12.3 5.7 2.3 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily MatE PF01554.18 KDO25629.1 - 3.8e-37 127.4 39.3 2.6e-19 69.4 15.2 2.6 3 0 0 3 3 3 2 MatE MatE PF01554.18 KDO25630.1 - 8.4e-25 87.3 30.3 1.6e-20 73.3 13.3 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO25630.1 - 0.2 11.7 42.8 0.33 11.0 19.9 4.3 1 1 3 4 4 4 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KDO25631.1 - 1.2e-38 132.3 32.5 4.9e-23 81.5 10.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KDO25631.1 - 0.011 15.8 16.0 0.011 15.8 16.0 4.8 3 2 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KDO25632.1 - 1.5e-40 138.5 35.9 1.3e-20 73.6 14.5 2.2 2 0 0 2 2 2 2 MatE DUF4714 PF15833.5 KDO25632.1 - 0.49 10.3 3.8 0.51 10.3 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4714) FHA PF00498.26 KDO25634.1 - 1.5e-13 50.8 0.1 1.2e-11 44.8 0.0 3.1 3 0 0 3 3 3 1 FHA domain RINGv PF12906.7 KDO25634.1 - 2.7e-13 49.8 5.1 7.3e-13 48.4 5.1 1.8 1 1 0 1 1 1 1 RING-variant domain Yop-YscD_cpl PF16697.5 KDO25634.1 - 5.2e-08 33.1 0.0 2.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 KDO25634.1 - 0.15 12.5 8.5 1.8 8.9 9.3 2.3 1 1 1 2 2 2 0 Ring finger domain Sec1 PF00995.23 KDO25635.1 - 1.9e-96 324.6 0.0 2.3e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HA PF03457.14 KDO25637.1 - 6.5e-16 58.4 0.0 0.0026 18.0 0.0 4.9 5 0 0 5 5 5 4 Helicase associated domain HA PF03457.14 KDO25638.1 - 3.9e-20 71.9 0.2 0.0027 18.0 0.0 6.6 7 0 0 7 7 7 4 Helicase associated domain DUF417 PF04224.12 KDO25638.1 - 0.16 11.5 0.1 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF417 HA PF03457.14 KDO25639.1 - 2.8e-21 75.6 1.6 1.8e-06 28.2 0.0 7.2 8 1 1 9 9 9 3 Helicase associated domain BcsB PF03170.13 KDO25639.1 - 0.087 11.2 0.1 0.5 8.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit Urease_linker PF18473.1 KDO25640.1 - 0.11 12.4 0.0 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Urease subunit beta-alpha linker domain Erp_C PF06780.11 KDO25640.1 - 0.28 11.2 1.6 7.1 6.6 0.2 2.0 1 1 1 2 2 2 0 Erp protein C-terminus HA PF03457.14 KDO25641.1 - 1.9e-23 82.6 0.1 0.0057 17.0 0.0 8.7 9 1 0 9 9 9 7 Helicase associated domain HA PF03457.14 KDO25642.1 - 5.7e-35 119.5 0.4 2.8e-07 30.8 0.0 13.0 14 0 0 14 14 14 9 Helicase associated domain HA PF03457.14 KDO25644.1 - 5.4e-56 186.8 0.0 6.6e-07 29.6 0.1 12.0 12 0 0 12 12 12 10 Helicase associated domain Gag_p10 PF02337.17 KDO25644.1 - 0.18 11.8 0.0 11 6.0 0.0 3.7 4 0 0 4 4 4 0 Retroviral GAG p10 protein BT1 PF03092.16 KDO25645.1 - 3.3e-09 35.5 0.3 3.3e-09 35.5 0.3 3.1 3 1 0 3 3 3 3 BT1 family CBM53 PF16760.5 KDO25646.1 - 0.068 13.8 0.2 0.14 12.7 0.2 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Sial-lect-inser PF09264.10 KDO25646.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion TFIIA PF03153.13 KDO25646.1 - 6.6 6.6 20.3 8.7 6.2 20.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tetraspanin PF00335.20 KDO25647.1 - 5e-23 82.0 11.3 5.9e-23 81.8 11.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Adeno_E3_CR2 PF02439.15 KDO25647.1 - 0.015 15.0 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF5518 PF17647.1 KDO25647.1 - 1.4 9.0 14.3 4.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5518) EphA2_TM PF14575.6 KDO25647.1 - 4.2 8.3 0.0 4.2 8.3 0.0 2.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SUR7 PF06687.12 KDO25647.1 - 6.6 6.3 9.0 6.1 6.4 3.5 2.4 1 1 1 2 2 2 0 SUR7/PalI family Tudor_4 PF18358.1 KDO25648.1 - 0.083 12.5 0.1 1 9.0 0.1 2.6 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain HA PF03457.14 KDO25649.1 - 1.2e-65 217.7 0.2 1.2e-08 35.1 0.0 11.1 11 0 0 11 11 11 8 Helicase associated domain HA PF03457.14 KDO25650.1 - 4.1e-40 135.9 0.0 1e-09 38.5 0.0 5.3 5 0 0 5 5 5 5 Helicase associated domain HA PF03457.14 KDO25651.1 - 2.8e-37 126.9 0.0 1.1e-07 32.1 0.0 10.7 11 0 0 11 11 11 8 Helicase associated domain GLEYA PF10528.9 KDO25652.1 - 0.11 13.0 0.2 2.8 8.4 0.3 2.3 2 0 0 2 2 2 0 GLEYA domain IGFL PF14653.6 KDO25653.1 - 0.058 13.4 2.0 0.15 12.0 2.0 1.6 1 0 0 1 1 1 0 Insulin growth factor-like family NdhN PF11909.8 KDO25653.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N VIT1 PF01988.19 KDO25654.1 - 3.2e-56 190.6 1.5 3.9e-56 190.3 1.5 1.1 1 0 0 1 1 1 1 VIT family GatB_Yqey PF02637.18 KDO25654.1 - 0.032 14.1 0.3 0.05 13.5 0.3 1.2 1 0 0 1 1 1 0 GatB domain VIT1 PF01988.19 KDO25655.1 - 2.3e-52 178.0 2.1 2.9e-52 177.7 2.1 1.1 1 0 0 1 1 1 1 VIT family GatB_Yqey PF02637.18 KDO25655.1 - 0.019 14.9 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 GatB domain ANAPC4_WD40 PF12894.7 KDO25656.1 - 5e-13 49.2 0.8 0.0052 17.1 0.1 5.3 6 0 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KDO25656.1 - 0.027 13.7 0.0 0.99 8.6 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KDO25656.1 - 0.16 12.9 11.4 3.6 8.6 0.2 5.0 5 2 1 6 6 6 0 WD domain, G-beta repeat BT1 PF03092.16 KDO25657.1 - 1.4e-12 46.6 8.1 7.9e-10 37.6 1.4 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO25657.1 - 0.00075 18.6 0.8 0.00075 18.6 0.8 2.0 2 0 0 2 2 2 1 PUCC protein DUF2085 PF09858.9 KDO25657.1 - 0.36 11.3 8.8 0.41 11.2 1.2 3.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) Pkinase_Tyr PF07714.17 KDO25658.1 - 1.3e-73 247.5 0.0 5.4e-25 88.2 0.0 5.2 4 1 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 KDO25658.1 - 6.9e-69 232.1 0.0 3e-29 102.2 0.0 5.7 4 1 0 4 4 4 4 Protein kinase domain Kinase-like PF14531.6 KDO25658.1 - 4.4e-12 45.9 0.0 0.0022 17.4 0.0 3.3 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 KDO25658.1 - 1.9e-07 30.6 2.7 0.39 10.0 0.0 4.2 4 0 0 4 4 4 3 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 KDO25658.1 - 1.6e-05 24.6 0.0 0.0072 16.0 0.0 2.9 3 0 0 3 3 3 2 Protein-kinase domain of FAM69 APH PF01636.23 KDO25658.1 - 0.0022 17.9 8.9 0.16 11.9 0.3 3.9 3 1 1 4 4 4 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO25658.1 - 0.012 15.3 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KDO25658.1 - 0.035 12.9 0.1 0.098 11.4 0.1 1.7 1 0 0 1 1 1 0 Fungal protein kinase UCH PF00443.29 KDO25659.1 - 4.7e-42 144.3 0.0 6.1e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO25659.1 - 0.0042 16.7 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SPX PF03105.19 KDO25659.1 - 5.8 6.7 6.0 8.4 6.2 6.0 1.1 1 0 0 1 1 1 0 SPX domain DCB PF16213.5 KDO25660.1 - 5.9e-31 107.5 2.2 5.9e-31 107.5 2.2 3.1 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KDO25660.1 - 1.3e-26 93.0 1.6 6.9e-24 84.0 0.3 3.3 3 1 0 3 3 3 1 C-terminal region of Mon2 protein Sec7_N PF12783.7 KDO25660.1 - 5.7e-09 36.1 0.2 5.7e-09 36.1 0.2 4.1 4 1 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KDO25660.1 - 8.7e-05 22.3 2.2 0.037 13.9 0.0 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF1981) DUF5076 PF16826.5 KDO25660.1 - 0.068 13.1 4.7 0.09 12.7 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) HEAT_EZ PF13513.6 KDO25660.1 - 0.17 12.4 1.6 3.3 8.3 0.1 4.1 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 KDO25660.1 - 0.28 11.6 7.4 1 9.8 0.1 4.7 4 0 0 4 4 4 0 HEAT repeats HECT PF00632.25 KDO25661.1 - 2.7e-88 296.4 0.0 4.5e-88 295.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_S8 PF00082.22 KDO25662.1 - 1.8e-41 142.3 0.4 1.8e-41 142.3 0.4 1.4 2 0 0 2 2 2 1 Subtilase family zf-Di19 PF05605.12 KDO25662.1 - 2e-07 31.2 7.7 0.00032 20.9 2.2 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KDO25662.1 - 0.00027 21.5 10.2 0.052 14.4 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KDO25662.1 - 0.0063 16.3 4.1 0.88 9.4 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KDO25662.1 - 0.0067 16.8 7.2 0.079 13.5 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zap1_zf2 PF18217.1 KDO25662.1 - 0.028 14.4 0.1 4.4 7.4 0.2 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 Nudix_N_2 PF14803.6 KDO25662.1 - 7.6 6.6 6.6 27 4.8 0.2 3.1 3 0 0 3 3 3 0 Nudix N-terminal HA PF03457.14 KDO25666.1 - 2e-58 194.6 0.1 5.8e-10 39.4 0.0 10.4 10 0 0 10 10 10 10 Helicase associated domain Gag_p10 PF02337.17 KDO25666.1 - 0.00032 20.6 0.0 10 6.1 0.0 4.4 5 0 0 5 5 5 3 Retroviral GAG p10 protein HA PF03457.14 KDO25667.1 - 6.4e-71 234.6 0.0 5.2e-08 33.1 0.0 16.5 18 0 0 18 18 18 13 Helicase associated domain DprA_WH PF17782.1 KDO25668.1 - 0.18 12.0 3.0 0.5 10.5 0.5 2.7 2 0 0 2 2 2 0 DprA winged helix domain Kazal_2 PF07648.15 KDO25669.1 - 0.00065 19.8 3.1 0.001 19.2 3.1 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO25669.1 - 0.038 14.0 3.5 0.13 12.3 3.1 2.1 1 1 1 2 2 2 0 Kazal-type serine protease inhibitor domain Glyco_hydro_19 PF00182.19 KDO25670.1 - 2.9e-43 148.4 6.3 5.8e-41 140.9 6.3 3.0 1 1 0 1 1 1 1 Chitinase class I Ion_trans PF00520.31 KDO25671.1 - 3.1e-18 65.9 11.2 4.6e-18 65.3 11.2 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO25671.1 - 2.2e-12 46.9 0.0 4.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO25671.1 - 1.2e-08 34.8 4.7 1.2e-08 34.8 4.7 1.7 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KDO25672.1 - 1.6e-20 73.4 16.5 1.3e-18 67.1 16.5 2.1 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO25672.1 - 5.5e-11 42.4 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO25672.1 - 5.3e-09 35.9 10.3 1.1e-08 34.9 9.6 2.0 1 1 0 1 1 1 1 Ion channel Rootletin PF15035.6 KDO25674.1 - 0.1 12.6 5.0 0.11 12.5 2.1 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion NSs PF11073.8 KDO25674.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like DUF2207 PF09972.9 KDO25674.1 - 0.19 10.4 0.0 0.21 10.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CLASP_N PF12348.8 KDO25676.1 - 0.0017 18.0 0.4 0.78 9.3 0.2 2.2 2 0 0 2 2 2 2 CLASP N terminal zf-RING_2 PF13639.6 KDO25676.1 - 0.095 13.1 0.3 0.25 11.7 0.3 1.8 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KDO25676.1 - 1.5 9.2 3.5 1.2 9.4 0.3 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Ion_trans PF00520.31 KDO25677.1 - 1.5e-26 93.1 11.0 2.1e-26 92.6 11.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO25677.1 - 2.2e-14 53.1 5.2 2.2e-14 53.1 5.2 2.0 2 0 0 2 2 2 1 Ion channel zinc_ribbon_2 PF13240.6 KDO25677.1 - 0.0006 19.5 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain PKD_channel PF08016.12 KDO25677.1 - 0.0012 17.7 1.6 0.0012 17.7 1.6 2.0 1 1 1 2 2 2 1 Polycystin cation channel IBR PF01485.21 KDO25677.1 - 0.045 14.0 0.2 0.079 13.2 0.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain MFS_MOT1 PF16983.5 KDO25677.1 - 0.14 12.6 4.6 4.8 7.6 1.1 2.4 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Ribosomal_L32p PF01783.23 KDO25678.1 - 0.62 10.4 0.1 0.62 10.4 0.1 2.6 3 0 0 3 3 3 0 Ribosomal L32p protein family HA PF03457.14 KDO25679.1 - 3e-24 85.1 0.0 3.5e-10 40.0 0.1 3.3 3 0 0 3 3 3 3 Helicase associated domain LRR_4 PF12799.7 KDO25680.1 - 0.017 15.6 0.1 5.6 7.5 0.0 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO25680.1 - 0.14 12.0 0.1 11 5.9 0.1 3.3 3 1 0 3 3 3 0 Leucine rich repeat PseudoU_synth_2 PF00849.22 KDO25682.1 - 1.8e-34 119.1 0.4 3.7e-34 118.1 0.2 1.6 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF677 PF05055.12 KDO25683.1 - 0.023 13.6 0.6 0.032 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PDZ PF00595.24 KDO25685.1 - 7.6e-05 23.0 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain HC2 PF07382.11 KDO25685.1 - 0.00014 22.0 27.4 0.00026 21.1 27.4 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 PDZ_2 PF13180.6 KDO25685.1 - 0.0076 16.6 0.1 0.0076 16.6 0.1 2.1 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KDO25685.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF572 PF04502.13 KDO25685.1 - 0.28 10.8 20.1 0.35 10.4 20.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FragX_IP PF05994.11 KDO25685.1 - 1.9 6.5 20.4 12 3.8 0.0 2.0 2 0 0 2 2 2 0 Cytoplasmic Fragile-X interacting family RR_TM4-6 PF06459.12 KDO25685.1 - 3.5 7.4 15.8 4.8 6.9 15.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 KDO25685.1 - 4.5 6.4 7.4 7.1 5.7 7.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Asp-B-Hydro_N PF05279.11 KDO25685.1 - 7.2 6.6 9.4 11 6.0 9.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hydrolase PF00702.26 KDO25686.1 - 0.0045 17.3 0.6 0.03 14.6 0.1 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NodS PF05401.11 KDO25686.1 - 0.09 12.4 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Hydrolase_3 PF08282.12 KDO25686.1 - 0.19 11.5 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KDO25688.1 - 4.9e-43 147.4 0.0 9.3e-43 146.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25688.1 - 5.3e-38 130.8 0.0 1.5e-37 129.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO25688.1 - 9e-05 22.8 7.0 0.00012 22.3 1.3 3.6 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO25688.1 - 0.0028 16.5 0.0 0.0041 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase VSP PF03302.13 KDO25688.1 - 0.0033 16.3 0.1 0.005 15.7 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3147 PF11345.8 KDO25688.1 - 0.023 15.0 0.6 0.11 12.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3147) PRIMA1 PF16101.5 KDO25688.1 - 0.14 12.2 7.3 0.16 12.0 5.8 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 LRR_8 PF13855.6 KDO25688.1 - 0.32 10.8 6.4 0.091 12.5 1.5 2.6 2 1 1 3 3 3 0 Leucine rich repeat End_beta_barrel PF12195.8 KDO25688.1 - 4.7 7.2 6.8 1.8 8.6 0.3 2.6 3 0 0 3 3 3 0 Beta barrel domain of bacteriophage endosialidase CAP_N PF01213.19 KDO25688.1 - 7.2 6.0 8.1 11 5.4 8.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nup96 PF12110.8 KDO25692.1 - 4.2e-41 141.0 7.6 1e-40 139.7 7.6 1.7 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KDO25692.1 - 9.2e-38 129.7 0.0 1.5e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KDO25692.1 - 8.8e-05 23.3 30.6 8.8e-05 23.3 30.6 11.1 2 2 6 8 8 8 3 Nucleoporin FG repeat region TLD PF07534.16 KDO25693.1 - 1.2e-30 106.5 0.0 1.8e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 TLD EF-hand_6 PF13405.6 KDO25693.1 - 0.1 12.6 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 KDO25694.1 - 2.9e-21 76.0 0.0 5.3e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25694.1 - 1.3e-15 57.4 0.0 3.5e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25694.1 - 0.00079 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO25694.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF2868 PF11067.8 KDO25694.1 - 2.3 7.6 4.6 6.8 6.1 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Pkinase_Tyr PF07714.17 KDO25695.1 - 2.9e-15 56.3 0.0 1.1e-08 34.7 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO25695.1 - 1.5e-13 50.7 0.0 4.4e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO25695.1 - 0.063 12.6 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KDO25696.1 - 3e-19 69.4 0.0 5.9e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25696.1 - 1.5e-12 47.3 0.0 4.4e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase MSP1_C PF07462.11 KDO25696.1 - 0.038 12.7 0.4 0.056 12.1 0.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Oberon_cc PF16312.5 KDO25696.1 - 1.3 9.0 12.9 2.3 8.2 12.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of Oberon OmpH PF03938.14 KDO25696.1 - 2 8.8 11.4 3.9 7.8 11.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 KDO25697.1 - 6.9e-17 61.7 0.0 4.9e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25697.1 - 2.4e-12 46.7 0.0 5.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KDO25697.1 - 0.0074 15.7 0.4 0.014 14.8 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HIP1_clath_bdg PF16515.5 KDO25697.1 - 0.042 14.4 0.9 0.1 13.3 0.9 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 KDO25698.1 - 2e-21 76.6 0.0 3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25698.1 - 3e-14 52.9 0.0 7.4e-14 51.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KDO25698.1 - 9.4e-10 39.0 0.2 2e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO25698.1 - 2.1e-09 37.5 0.2 2.9e-05 24.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25698.1 - 4.7e-09 36.6 0.1 1.1e-05 25.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25698.1 - 2e-08 33.8 0.1 0.058 14.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO25698.1 - 1.1e-06 28.8 0.8 0.012 16.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Kinase-like PF14531.6 KDO25698.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CHASE3 PF05227.13 KDO25698.1 - 0.049 13.6 5.4 0.12 12.3 5.4 1.6 1 0 0 1 1 1 0 CHASE3 domain Kdo PF06293.14 KDO25698.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OmpH PF03938.14 KDO25698.1 - 0.6 10.4 2.9 1.1 9.6 2.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sugarporin_N PF11471.8 KDO25698.1 - 1.3 9.1 6.0 4.7 7.3 6.0 1.9 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension APC_N_CC PF16689.5 KDO25699.1 - 0.4 10.8 3.1 0.97 9.5 0.8 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain WD40 PF00400.32 KDO25701.1 - 1.2e-10 41.8 6.9 0.038 14.9 0.0 6.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25701.1 - 0.0003 21.0 0.0 0.041 14.2 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KDO25701.1 - 0.052 13.5 0.2 0.17 11.9 0.2 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat BT1 PF03092.16 KDO25702.1 - 3.6e-11 42.0 0.5 3.6e-11 42.0 0.5 3.6 2 1 0 4 4 4 3 BT1 family PUCC PF03209.15 KDO25702.1 - 0.0019 17.3 7.5 0.0032 16.6 2.3 2.9 2 1 0 2 2 2 1 PUCC protein BT1 PF03092.16 KDO25703.1 - 1.3e-09 36.8 15.8 2.5e-09 35.9 3.4 2.7 2 1 1 3 3 3 2 BT1 family bZIP_1 PF00170.21 KDO25706.1 - 0.012 15.7 3.2 0.059 13.5 2.9 2.1 2 0 0 2 2 2 0 bZIP transcription factor HTH_38 PF13936.6 KDO25707.1 - 0.0042 16.8 0.1 0.021 14.6 0.1 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain Ank_2 PF12796.7 KDO25708.1 - 8.5e-88 289.1 50.2 9.9e-15 54.9 0.6 10.1 4 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25708.1 - 6.1e-67 221.2 36.2 4.8e-08 33.4 0.6 14.5 8 4 7 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25708.1 - 1.2e-60 194.3 36.4 0.00085 19.6 0.1 19.5 19 0 0 19 19 19 16 Ankyrin repeat Ank_5 PF13857.6 KDO25708.1 - 2.6e-49 164.6 49.2 1.4e-07 31.6 0.3 16.0 6 4 11 17 17 17 14 Ankyrin repeats (many copies) Ank PF00023.30 KDO25708.1 - 4.3e-42 140.8 50.5 0.0014 18.9 0.2 20.1 20 0 0 20 20 20 14 Ankyrin repeat Sec7 PF01369.20 KDO25709.1 - 1.7e-51 174.5 0.0 2.7e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KDO25709.1 - 5.9e-19 68.5 0.5 3.4e-18 66.0 0.1 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MinE PF03776.14 KDO25710.1 - 3.1e-15 55.9 0.0 3.9e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE BRCT PF00533.26 KDO25711.1 - 9.1e-12 45.2 0.0 6.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KDO25711.1 - 8.7e-06 26.1 0.0 0.00032 21.1 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4 PF00097.25 KDO25711.1 - 4.5e-05 23.2 13.4 8.4e-05 22.4 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO25711.1 - 7.8e-05 22.4 12.2 0.00016 21.5 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KDO25711.1 - 0.00013 22.0 6.7 0.00026 21.0 6.7 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KDO25711.1 - 0.00024 20.9 5.4 0.00044 20.1 5.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KDO25711.1 - 0.0014 18.6 10.4 0.003 17.5 10.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO25711.1 - 0.0015 18.6 10.7 0.0029 17.7 10.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KDO25711.1 - 0.0054 16.6 12.0 0.0096 15.8 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO25711.1 - 0.15 12.4 12.1 0.3 11.5 12.1 1.5 1 0 0 1 1 1 0 Ring finger domain Osteopontin PF00865.18 KDO25711.1 - 0.26 10.7 8.3 0.4 10.1 8.3 1.2 1 0 0 1 1 1 0 Osteopontin zf-RING_5 PF14634.6 KDO25711.1 - 0.87 9.6 13.1 1.8 8.6 13.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO25711.1 - 6.6 6.7 10.9 13 5.7 10.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Metallophos PF00149.28 KDO25712.1 - 2.4e-13 51.0 1.3 3.3e-13 50.6 0.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO25712.1 - 3.9e-11 43.6 0.1 2.9e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KDO25712.1 - 5.3e-06 26.9 4.2 5.5e-06 26.9 0.3 2.8 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 KDO25712.1 - 0.0049 17.1 0.0 2.6 8.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Clat_adaptor_s PF01217.20 KDO25715.1 - 1.1e-54 184.2 1.2 1.4e-54 183.9 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1771 PF08590.10 KDO25716.1 - 6.7e-17 61.6 10.7 1.6e-16 60.4 10.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KDO25716.1 - 4.7e-11 42.9 0.5 1.5e-10 41.2 0.2 2.0 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 KDO25716.1 - 5.1e-08 32.7 10.3 1.4e-05 25.0 1.9 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KDO25716.1 - 3.9e-05 23.3 9.6 0.0014 18.4 0.4 2.7 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KDO25716.1 - 0.00044 20.1 9.1 0.12 12.3 1.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KDO25716.1 - 0.00069 20.0 5.9 0.008 16.6 0.3 2.3 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KDO25716.1 - 0.0013 19.4 6.3 0.04 14.6 1.2 2.6 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KDO25716.1 - 1.6 8.9 7.0 15 5.8 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger containing family EF-hand_1 PF00036.32 KDO25717.1 - 1.8e-38 127.2 11.6 3.7e-06 26.1 0.1 8.8 8 0 0 8 8 8 7 EF hand EF-hand_7 PF13499.6 KDO25717.1 - 6.5e-37 125.8 6.7 2.2e-08 34.4 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KDO25717.1 - 6.4e-35 116.1 11.4 0.00085 19.1 0.0 8.9 9 0 0 9 9 9 8 EF-hand domain EF-hand_5 PF13202.6 KDO25717.1 - 4e-28 95.6 16.6 8.5e-05 21.9 0.0 8.4 8 0 0 8 8 8 7 EF hand EF-hand_8 PF13833.6 KDO25717.1 - 2.5e-17 62.4 19.4 2.4e-07 30.5 0.3 6.8 6 1 1 7 7 7 4 EF-hand domain pair HU-CCDC81_euk_2 PF18289.1 KDO25717.1 - 2.1e-06 27.8 0.0 4.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 Dockerin_1 PF00404.18 KDO25717.1 - 0.00017 21.7 6.9 7.1 6.9 0.4 5.7 6 0 0 6 6 6 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KDO25717.1 - 0.0058 16.9 0.0 11 6.4 0.0 4.4 3 2 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO25717.1 - 0.38 10.7 1.2 12 5.9 0.0 3.2 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 KDO25717.1 - 3.7 7.6 8.5 0.46 10.4 3.7 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif EF-hand_7 PF13499.6 KDO25721.1 - 8.1e-22 77.5 8.4 3.7e-12 46.5 3.4 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO25721.1 - 5e-21 72.6 7.9 8.1e-07 28.2 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO25721.1 - 6.6e-19 66.2 4.8 4e-07 29.4 0.2 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KDO25721.1 - 1.6e-16 59.9 5.0 1.4e-10 40.8 1.9 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO25721.1 - 2.6e-15 55.1 6.3 9.4e-05 21.7 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KDO25721.1 - 8.9e-08 32.3 0.4 0.0058 16.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 KDO25721.1 - 5.2e-06 27.3 1.8 0.099 13.5 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain Mlo PF03094.15 KDO25721.1 - 2e-05 23.2 2.4 0.0026 16.2 0.3 2.3 2 0 0 2 2 2 2 Mlo family DUF996 PF06195.13 KDO25721.1 - 0.061 13.6 0.1 0.061 13.6 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF996) SPARC_Ca_bdg PF10591.9 KDO25721.1 - 0.23 11.8 4.9 1.4 9.3 1.0 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO25721.1 - 0.48 10.4 5.3 18 5.4 1.9 3.1 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.17 KDO25721.1 - 0.48 11.1 2.2 12 6.5 0.4 2.5 2 0 0 2 2 2 0 MgtE intracellular N domain DUF1980 PF09323.10 KDO25721.1 - 0.97 9.3 3.7 5.4 6.9 1.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) MRAP PF15183.6 KDO25721.1 - 2.2 8.3 5.1 6 6.9 0.5 3.1 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Mg_trans_NIPA PF05653.14 KDO25722.1 - 5.7e-20 71.6 16.2 2.1e-17 63.2 16.2 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF4235 PF14019.6 KDO25722.1 - 0.74 9.9 0.1 0.74 9.9 0.1 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF4235) Trypsin_2 PF13365.6 KDO25723.1 - 4.2e-19 69.9 0.3 1.1e-18 68.5 0.2 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO25723.1 - 6.2e-06 26.2 2.1 1.3e-05 25.2 2.1 1.5 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KDO25723.1 - 4.2 5.9 5.3 1.3 7.6 1.4 1.8 2 0 0 2 2 2 0 Peptidase S46 FUSC-like PF12805.7 KDO25726.1 - 0.0062 15.6 0.8 0.011 14.9 0.8 1.3 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS S1FA PF04689.13 KDO25726.1 - 0.079 13.1 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA Cons_hypoth95 PF03602.15 KDO25728.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PSD2 PF07624.11 KDO25730.1 - 0.047 13.5 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) 2TM PF13239.6 KDO25730.1 - 0.053 13.8 0.1 0.085 13.2 0.1 1.3 1 0 0 1 1 1 0 2TM domain FGFR3_TM PF18123.1 KDO25730.1 - 0.061 12.8 0.5 0.061 12.8 0.5 1.7 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain 2OG-FeII_Oxy_3 PF13640.6 KDO25732.1 - 8.8e-18 65.0 0.0 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KDO25732.1 - 2.6e-07 31.2 0.0 4.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4551 PF15087.6 KDO25732.1 - 0.6 8.9 1.4 0.76 8.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NAM-associated PF14303.6 KDO25732.1 - 8.1 7.1 8.0 13 6.5 8.0 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain IQ PF00612.27 KDO25733.1 - 0.00024 20.6 48.3 0.041 13.7 0.7 7.8 7 0 0 7 7 7 5 IQ calmodulin-binding motif zf-Di19 PF05605.12 KDO25733.1 - 0.00049 20.3 0.4 0.0015 18.8 0.4 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KDO25733.1 - 0.014 15.8 4.8 0.017 15.5 1.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO25733.1 - 0.019 15.8 1.4 0.019 15.8 1.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger PH PF00169.29 KDO25734.1 - 2.3e-15 57.0 0.1 4.8e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 PH domain RGS PF00615.19 KDO25734.1 - 1.7e-09 38.0 0.0 8e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain RA PF00788.23 KDO25734.1 - 1.3e-06 29.0 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 KDO25734.1 - 1.5e-05 25.3 0.1 0.00024 21.5 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO25734.1 - 0.0043 17.3 0.2 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PLN_propep PF16485.5 KDO25734.1 - 0.057 13.1 0.1 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Protealysin propeptide USP7_C2 PF14533.6 KDO25734.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF4291 PF14124.6 KDO25735.1 - 2.6e-51 174.0 0.0 3.1e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) TRP PF06011.12 KDO25736.1 - 0.013 14.2 4.7 0.59 8.8 4.7 2.1 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel TBCC PF07986.12 KDO25737.1 - 1e-40 138.2 0.5 2.1e-40 137.2 0.5 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Clathrin_lg_ch PF01086.17 KDO25737.1 - 5.4e-14 52.8 5.5 8.9e-14 52.1 5.5 1.3 1 0 0 1 1 1 1 Clathrin light chain BBP1_N PF15271.6 KDO25737.1 - 1.3 9.8 5.5 1.1 10.1 1.7 2.3 1 1 1 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein LRR_6 PF13516.6 KDO25738.1 - 5.7e-25 85.2 11.1 0.00073 19.4 0.6 7.6 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 KDO25738.1 - 7.8e-07 29.3 7.6 0.07 13.6 0.2 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO25738.1 - 0.023 14.5 7.3 2.8 7.8 0.3 4.8 3 2 0 3 3 3 0 Leucine rich repeat LRR_2 PF07723.13 KDO25738.1 - 0.04 14.6 0.3 49 4.8 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4946 PF16304.5 KDO25738.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) LRR_1 PF00560.33 KDO25738.1 - 0.47 11.2 7.7 79 4.4 0.0 5.5 5 2 0 5 5 5 0 Leucine Rich Repeat Paf67 PF10255.9 KDO25740.1 - 3.9e-99 332.4 5.7 1.1e-98 330.9 5.7 1.6 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DcpS_C PF11969.8 KDO25741.1 - 2.3e-12 47.4 1.7 1.4e-06 28.7 0.0 2.1 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KDO25741.1 - 3.4e-07 30.9 0.5 0.00015 22.5 0.0 2.1 2 0 0 2 2 2 2 HIT domain Jacalin PF01419.17 KDO25742.1 - 1.2e-09 38.2 0.1 3.2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Jacalin-like lectin domain POX PF07526.11 KDO25743.1 - 0.12 12.9 0.2 0.36 11.4 0.2 1.8 1 0 0 1 1 1 0 Associated with HOX DUF1298 PF06974.13 KDO25746.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) FYVE PF01363.21 KDO25747.1 - 5.4e-15 55.3 9.9 5.4e-15 55.3 9.9 3.0 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO25747.1 - 4.7e-06 26.8 6.0 4.7e-06 26.8 6.0 2.9 2 1 1 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KDO25747.1 - 1.1e-05 25.6 6.7 1.1e-05 25.6 6.7 2.8 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO25747.1 - 2.7e-05 23.9 5.3 2.7e-05 23.9 5.3 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO25747.1 - 0.00073 19.4 2.7 0.00073 19.4 2.7 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KDO25747.1 - 0.012 15.9 5.5 0.012 15.9 5.5 1.9 2 1 0 2 2 2 0 FYVE-type zinc finger zf-ANAPC11 PF12861.7 KDO25747.1 - 0.017 15.2 2.6 0.017 15.2 2.6 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KDO25747.1 - 3.3 7.8 22.4 11 6.1 2.3 3.6 1 1 1 2 2 2 0 Double zinc ribbon zf_C2H2_10 PF18414.1 KDO25747.1 - 6.3 6.4 9.4 0.98 9.0 2.2 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger FYVE PF01363.21 KDO25748.1 - 5.4e-10 39.3 9.8 5.4e-10 39.3 9.8 2.9 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO25748.1 - 1.9e-07 31.3 5.6 1.9e-07 31.3 5.6 3.5 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO25748.1 - 0.00024 20.9 7.6 0.00024 20.9 7.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO25748.1 - 0.0026 17.4 4.3 0.0026 17.4 4.3 2.8 4 0 0 4 4 4 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO25748.1 - 0.0029 17.8 8.2 0.0029 17.8 8.2 3.6 2 2 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO25748.1 - 0.0092 15.9 6.3 0.0092 15.9 6.3 3.0 2 1 0 2 2 2 1 zinc-RING finger domain Vps39_2 PF10367.9 KDO25748.1 - 0.066 13.7 1.7 0.066 13.7 1.7 2.8 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-C2HC5 PF06221.13 KDO25748.1 - 8 6.5 15.6 11 6.0 7.5 3.8 3 1 0 3 3 3 0 Putative zinc finger motif, C2HC5-type AbiEi_1 PF09407.10 KDO25749.1 - 0.053 13.8 0.1 12 6.3 0.1 2.3 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain PH PF00169.29 KDO25750.1 - 0.0004 20.8 0.0 0.00078 19.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Apt1 PF10351.9 KDO25750.1 - 0.25 10.1 6.0 0.45 9.3 6.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ank_5 PF13857.6 KDO25751.1 - 3.1e-17 62.4 0.1 2.6e-09 37.2 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25751.1 - 2.3e-15 56.7 0.2 1.1e-10 41.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO25751.1 - 2.5e-15 56.8 0.0 4.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO25751.1 - 1.5e-14 52.6 0.1 7.2e-06 26.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO25751.1 - 2.3e-12 46.8 0.5 5.5e-07 29.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ricin_B_lectin PF00652.22 KDO25752.1 - 3.4e-15 56.4 0.1 8e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO25752.1 - 1.8e-05 25.3 0.0 0.0006 20.5 0.0 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SPX PF03105.19 KDO25752.1 - 1.4 8.7 11.7 1.8 8.4 11.7 1.1 1 0 0 1 1 1 0 SPX domain EF-hand_1 PF00036.32 KDO25753.1 - 3.1e-11 42.0 0.0 2.4e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO25753.1 - 9.1e-10 37.7 0.5 0.0017 18.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO25753.1 - 3.3e-09 35.8 0.5 0.002 17.5 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO25753.1 - 5.8e-08 33.1 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO25753.1 - 1.1e-06 28.4 0.9 0.0058 16.4 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO25753.1 - 0.061 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain SAM_PNT PF02198.16 KDO25753.1 - 0.087 12.8 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain PAP_assoc PF03828.19 KDO25754.1 - 1.3e-11 44.5 0.1 3.2e-11 43.3 0.1 1.7 1 1 0 1 1 1 1 Cid1 family poly A polymerase Nrap_D2 PF17403.2 KDO25754.1 - 0.0061 16.3 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain NTP_transf_2 PF01909.23 KDO25754.1 - 0.0081 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KDO25754.1 - 0.038 14.1 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PAP_central PF04928.17 KDO25754.1 - 0.12 11.4 0.2 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Poly(A) polymerase central domain SR-25 PF10500.9 KDO25754.1 - 0.37 10.4 7.7 0.54 9.8 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 KDO25755.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) S-methyl_trans PF02574.16 KDO25756.1 - 0.12 12.2 1.4 0.18 11.5 1.4 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase NO_synthase PF02898.15 KDO25756.1 - 0.75 8.8 7.5 1 8.3 7.5 1.1 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain DUF4407 PF14362.6 KDO25756.1 - 4.3 6.6 13.4 6.4 6.0 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_transf_41 PF13844.6 KDO25757.1 - 1.4e-11 43.5 0.2 1.1e-08 34.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 KDO25757.1 - 4.1e-10 39.0 1.5 0.00095 19.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25757.1 - 1.2e-08 34.4 0.0 0.0005 19.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO25757.1 - 1.5e-06 28.2 5.2 0.0001 22.4 0.1 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25757.1 - 8.7e-06 26.2 9.9 0.6 11.1 0.0 6.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO25757.1 - 2.6e-05 24.3 1.1 1.1 9.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 KDO25757.1 - 0.00034 20.5 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 TPR_11 PF13414.6 KDO25757.1 - 0.00062 19.4 0.9 1.4 8.7 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 KDO25757.1 - 0.0008 19.3 0.3 0.23 11.6 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25757.1 - 0.0012 19.1 11.7 0.0026 18.0 0.0 4.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25757.1 - 0.004 17.2 0.0 0.33 11.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25757.1 - 0.012 16.3 13.9 0.14 12.8 0.0 4.2 1 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25757.1 - 0.05 13.5 1.2 21 5.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 KDO25758.1 - 1.1e-160 536.0 16.7 2.4e-159 531.6 13.7 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 KDO25758.1 - 4.5e-12 45.2 15.4 4.1e-06 26.6 0.0 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25758.1 - 1.1e-09 37.6 35.6 2.1e-07 30.6 0.1 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25758.1 - 1.6e-08 34.0 17.5 8.8e-07 28.5 0.2 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25758.1 - 5e-08 33.1 13.5 0.0042 17.3 0.4 5.3 2 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KDO25758.1 - 7.9e-08 31.9 15.5 1.7e-07 30.8 0.5 4.4 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 KDO25758.1 - 1.8e-07 31.5 27.8 0.0013 19.2 0.3 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO25758.1 - 3.4e-07 30.2 4.2 0.16 12.4 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25758.1 - 3.7e-07 30.4 41.4 0.0003 21.3 0.1 9.9 10 2 3 13 13 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25758.1 - 5.6e-07 29.1 8.0 0.00035 20.4 0.1 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO25758.1 - 2e-06 27.8 12.3 0.12 12.5 0.2 5.9 6 0 0 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KDO25758.1 - 1.5e-05 25.1 5.2 0.05 13.7 0.6 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25758.1 - 7.1e-05 23.0 18.6 0.047 14.0 0.2 6.5 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25758.1 - 0.00025 21.6 42.3 0.0044 17.6 0.2 8.9 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO25758.1 - 3.4 8.5 26.0 0.97 10.2 0.1 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25758.1 - 5 7.1 13.0 1.3 9.0 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DinB_2 PF12867.7 KDO25760.1 - 0.1 13.1 4.9 0.89 10.1 0.5 2.2 2 0 0 2 2 2 0 DinB superfamily DUF4407 PF14362.6 KDO25760.1 - 1.7 8.0 15.8 2.4 7.4 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_1 PF00561.20 KDO25761.1 - 6.1e-07 29.3 0.0 9.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO25761.1 - 2e-05 24.0 0.0 0.75 9.0 0.0 3.1 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO25761.1 - 0.00037 20.6 0.0 0.00094 19.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein VEGFR-2_TMD PF17988.1 KDO25761.1 - 0.13 11.7 0.9 0.31 10.5 0.9 1.7 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Gram_pos_anchor PF00746.21 KDO25761.1 - 0.17 11.9 0.5 0.61 10.1 0.5 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Abhydrolase_1 PF00561.20 KDO25763.1 - 3.9e-09 36.5 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO25763.1 - 5.4e-06 25.8 0.0 8.9e-05 21.9 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO25763.1 - 0.0016 18.5 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Podoplanin PF05808.11 KDO25763.1 - 0.0081 16.3 0.3 0.022 14.8 0.3 1.7 1 0 0 1 1 1 1 Podoplanin PLDc PF00614.22 KDO25764.1 - 1.2e-15 57.0 2.7 1.3e-07 31.5 0.1 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KDO25764.1 - 5.9e-12 45.6 0.1 2.3e-06 27.5 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KDO25764.1 - 0.002 18.1 0.6 0.0083 16.1 0.6 2.1 1 0 0 1 1 1 1 PX domain Pex24p PF06398.11 KDO25764.1 - 0.0034 16.4 3.7 0.0093 15.0 3.7 1.7 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PH PF00169.29 KDO25764.1 - 0.0067 16.9 0.0 0.22 12.1 0.0 2.5 2 0 0 2 2 2 1 PH domain Metallophos PF00149.28 KDO25765.1 - 1.1e-12 48.9 0.8 1.8e-12 48.2 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO25765.1 - 3.1e-07 31.1 0.1 1.4e-06 29.1 0.1 2.2 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 KDO25765.1 - 1.2e-05 25.6 0.0 0.00029 21.1 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pur_ac_phosph_N PF16656.5 KDO25765.1 - 3e-05 24.5 0.3 0.00021 21.8 0.1 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Utp12 PF04003.12 KDO25766.1 - 0.0079 16.5 0.3 0.021 15.1 0.3 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family MMR_HSR1_C PF08438.10 KDO25767.1 - 3.4e-34 117.8 0.1 5.6e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KDO25767.1 - 1.5e-20 73.4 0.0 4.4e-20 71.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO25767.1 - 9.2e-10 38.3 0.1 9.8e-09 34.9 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 KDO25767.1 - 0.0026 17.8 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain GHMP_kinases_N PF00288.26 KDO25767.1 - 0.032 14.5 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 GHMP kinases N terminal domain ATP_bind_1 PF03029.17 KDO25767.1 - 0.23 11.2 0.4 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3730 PF12530.8 KDO25768.1 - 2e-12 47.2 3.2 2e-12 47.2 3.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 KDO25768.1 - 0.023 14.9 0.8 16 6.1 0.4 4.5 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 KDO25768.1 - 0.44 11.1 12.6 5 7.7 0.3 5.9 4 0 0 4 4 4 0 HEAT-like repeat GlcNAc PF11397.8 KDO25769.1 - 2.9e-57 194.7 1.2 1.3e-50 172.9 0.1 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Vta1 PF04652.16 KDO25770.1 - 7.2 6.6 6.6 26 4.8 0.3 2.2 2 0 0 2 2 2 0 Vta1 like ABC_tran PF00005.27 KDO25771.1 - 1.5e-53 181.0 0.0 3.7e-26 92.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO25771.1 - 2.3e-29 102.6 37.3 1.2e-15 57.5 9.3 2.4 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO25771.1 - 8.3e-14 52.1 1.2 0.0014 18.5 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO25771.1 - 0.00017 21.3 1.4 0.41 10.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO25771.1 - 0.00033 21.2 0.3 1.1 9.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KDO25771.1 - 0.0024 17.4 0.4 7.1 6.0 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KDO25771.1 - 0.0054 16.0 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.22 KDO25771.1 - 0.0081 15.8 1.1 1.7 8.3 0.1 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KDO25771.1 - 0.011 16.2 0.1 3.7 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KDO25771.1 - 0.037 14.3 0.3 7.6 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 KDO25771.1 - 0.056 14.2 0.0 7.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_30 PF13604.6 KDO25771.1 - 0.063 13.0 0.7 10 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KDO25771.1 - 0.12 12.1 0.2 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KDO25771.1 - 0.15 11.9 1.5 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF87 PF01935.17 KDO25771.1 - 0.42 10.7 1.7 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Myb_DNA-binding PF00249.31 KDO25772.1 - 0.00031 20.9 0.1 1.4 9.1 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltr_RsmB-F PF01189.17 KDO25773.1 - 4.1e-40 137.6 0.0 4.3e-39 134.2 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F zf-CCHC_2 PF13696.6 KDO25773.1 - 2.5e-08 33.5 4.9 4.7e-08 32.7 4.9 1.5 1 0 0 1 1 1 1 Zinc knuckle FtsJ PF01728.19 KDO25773.1 - 0.0049 17.0 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-CCHC PF00098.23 KDO25773.1 - 0.014 15.5 0.6 0.027 14.5 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Hormone_4 PF00220.17 KDO25773.1 - 0.34 11.0 1.4 0.8 9.8 1.4 1.6 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain LCM PF04072.14 KDO25775.1 - 1.3e-29 103.4 0.0 1e-28 100.6 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TLP-20 PF06088.11 KDO25776.1 - 0.28 11.0 1.1 0.32 10.9 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Glucan_synthase PF02364.15 KDO25777.1 - 2.9e-188 627.8 19.3 6.8e-187 623.3 11.8 2.8 2 1 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO25777.1 - 7.2e-23 81.3 1.7 8.3e-22 77.9 1.7 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 KDO25777.1 - 4.3e-15 55.5 28.3 1.6e-14 53.6 28.3 2.0 1 0 0 1 1 1 1 Sugar (and other) transporter TPR_11 PF13414.6 KDO25778.1 - 0.0076 15.9 1.1 0.029 14.0 0.0 2.6 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 KDO25778.1 - 0.01 16.2 0.1 0.18 12.3 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25778.1 - 0.01 16.0 0.2 0.39 11.1 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25778.1 - 0.51 10.6 12.9 5.4 7.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25778.1 - 0.98 9.3 4.2 21 5.1 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DnaJ PF00226.31 KDO25779.1 - 1.1e-22 79.9 2.5 1.7e-22 79.3 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3516 PF12029.8 KDO25779.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) FTCD_C PF04961.12 KDO25779.1 - 0.12 12.1 0.6 1.6 8.5 0.4 2.0 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF4217 PF13959.6 KDO25779.1 - 0.22 11.8 0.8 0.87 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) WD40 PF00400.32 KDO25781.1 - 1.4e-41 139.6 26.6 1.4e-08 35.2 0.6 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25781.1 - 3.2e-24 85.0 4.1 0.001 19.3 0.0 7.5 2 2 6 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO25781.1 - 6.1e-11 42.6 0.1 0.00015 21.7 0.0 3.6 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KDO25781.1 - 6.3e-10 38.6 0.3 1.2e-09 37.8 0.3 1.5 1 0 0 1 1 1 1 LisH Coatomer_WDAD PF04053.14 KDO25781.1 - 0.0046 16.1 1.9 0.43 9.6 0.1 2.6 2 1 1 3 3 3 2 Coatomer WD associated region Nbas_N PF15492.6 KDO25781.1 - 0.018 14.4 0.7 2.6 7.3 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KDO25781.1 - 0.022 13.4 1.8 3.4 6.2 0.0 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO25781.1 - 0.097 11.6 3.5 17 4.2 0.1 4.0 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KDO25781.1 - 0.15 10.0 0.3 12 3.7 0.1 2.6 1 1 0 2 2 2 0 IKI3 family NAD_binding_2 PF03446.15 KDO25782.1 - 3.1e-49 167.2 1.5 4.4e-49 166.7 1.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KDO25782.1 - 1.1e-31 109.6 0.6 1.6e-31 109.1 0.0 1.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KDO25782.1 - 3.7e-07 29.7 0.1 6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KDO25782.1 - 3.9e-07 30.6 0.1 5.4e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KDO25782.1 - 1.3e-05 25.1 0.3 0.0001 22.3 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KDO25782.1 - 0.00072 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 KDO25782.1 - 0.0026 17.3 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 KDO25782.1 - 0.0034 17.0 0.4 0.015 14.9 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KDO25782.1 - 0.0043 17.3 0.3 0.038 14.3 0.1 2.3 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain PDH PF02153.17 KDO25782.1 - 0.011 14.7 0.4 0.016 14.2 0.4 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase ApbA PF02558.16 KDO25782.1 - 0.018 14.7 0.2 0.031 13.9 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 KDO25782.1 - 0.072 13.9 0.2 0.17 12.7 0.2 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold LRR_4 PF12799.7 KDO25783.1 - 1.3e-16 60.4 22.2 3.9e-08 33.5 3.6 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO25783.1 - 7e-12 45.2 2.6 1e-05 25.1 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KDO25783.1 - 7.3e-12 44.9 25.8 3e-05 23.7 1.5 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 KDO25783.1 - 0.0097 16.3 10.6 5 8.1 0.5 4.8 4 2 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO25783.1 - 0.49 10.6 8.5 17 5.7 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Hydrolase_6 PF13344.6 KDO25784.1 - 3.7e-23 81.5 0.0 6.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO25784.1 - 6.7e-18 64.5 0.0 2.3e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 KDO25784.1 - 0.02 15.0 0.0 0.6 10.2 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TCR PF03638.15 KDO25785.1 - 4.4e-23 81.3 58.6 7.6e-13 48.5 24.6 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KDO25785.1 - 5.4 7.2 50.2 0.35 11.0 17.4 2.7 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Prefoldin PF02996.17 KDO25787.1 - 1.3e-27 96.1 0.1 1.6e-27 95.8 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Cauli_AT PF03233.13 KDO25787.1 - 0.033 14.1 0.2 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Aphid transmission protein Prefoldin_2 PF01920.20 KDO25787.1 - 0.063 13.2 0.0 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit SAT PF16073.5 KDO25790.1 - 0.066 12.9 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis NiFeSe_Hases PF00374.19 KDO25790.1 - 0.068 12.1 0.4 0.096 11.6 0.4 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase SDF PF00375.18 KDO25791.1 - 2.6e-69 234.1 38.4 1.3e-68 231.8 38.4 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family LRR_6 PF13516.6 KDO25792.1 - 0.13 12.4 5.4 0.3 11.2 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat TPP_enzyme_C PF02775.21 KDO25794.1 - 0.04 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ank_2 PF12796.7 KDO25795.1 - 4.2e-34 117.0 23.5 3.5e-11 43.5 0.2 5.1 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25795.1 - 8.7e-24 83.6 9.3 1.8e-05 25.2 0.0 5.2 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25795.1 - 1.4e-15 55.8 14.9 0.014 15.8 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KDO25795.1 - 2.8e-15 56.2 19.6 4e-07 30.2 0.1 6.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO25795.1 - 2.2e-11 43.7 28.0 0.0013 19.1 0.3 7.9 9 0 0 9 9 9 4 Ankyrin repeat Ank_2 PF12796.7 KDO25796.1 - 1.1e-08 35.6 0.1 1.4e-08 35.2 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO25796.1 - 5.7e-08 32.9 1.2 0.0015 18.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO25796.1 - 5e-06 26.4 0.4 0.00067 19.9 0.1 3.3 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KDO25796.1 - 7.7e-06 26.1 0.3 0.00015 21.9 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25796.1 - 8.8e-06 26.2 0.3 0.00026 21.5 0.1 2.8 1 1 1 3 3 3 2 Ankyrin repeats (many copies) BT1 PF03092.16 KDO25797.1 - 4.1e-15 55.0 1.5 4.1e-15 55.0 1.5 2.4 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 KDO25797.1 - 6.4e-09 35.2 33.5 6.4e-09 35.2 33.5 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily Otopetrin PF03189.13 KDO25797.1 - 0.012 14.5 4.7 0.019 13.8 4.7 1.3 1 0 0 1 1 1 0 Otopetrin Gate PF07670.14 KDO25797.1 - 0.027 14.7 2.8 0.25 11.6 0.3 2.8 2 0 0 2 2 2 0 Nucleoside recognition DEAD PF00270.29 KDO25798.1 - 6.4e-47 159.6 0.9 6.7e-46 156.3 0.1 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO25798.1 - 2.6e-31 108.2 0.2 1.1e-30 106.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KDO25798.1 - 0.00056 19.3 0.1 0.00056 19.3 0.1 2.3 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Porin_3 PF01459.22 KDO25799.1 - 3.1e-10 40.0 0.1 5.8e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic porin BCL_N PF04714.13 KDO25802.1 - 0.0064 16.5 0.6 0.017 15.2 0.6 1.7 1 0 0 1 1 1 1 BCL7, N-terminal conserver region GCV_T PF01571.21 KDO25803.1 - 9e-84 280.9 0.0 1.2e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KDO25803.1 - 2.3e-18 65.9 0.0 4.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SPOB_ab PF14682.6 KDO25803.1 - 0.22 11.6 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal FYVE PF01363.21 KDO25805.1 - 2.5e-15 56.3 10.4 5.1e-15 55.4 10.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO25805.1 - 5.4e-07 30.3 0.0 1.7e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO25805.1 - 0.0022 18.2 6.0 0.007 16.6 6.0 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 KDO25805.1 - 0.011 16.1 0.0 0.042 14.2 0.0 2.0 2 0 0 2 2 2 0 GAF domain LRR_6 PF13516.6 KDO25806.1 - 1.1e-05 25.1 12.1 0.0093 16.0 0.5 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KDO25806.1 - 1.1e-05 25.6 2.7 0.034 14.6 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) IQ PF00612.27 KDO25806.1 - 0.0014 18.2 37.1 0.069 13.0 0.5 7.3 6 0 0 6 6 6 3 IQ calmodulin-binding motif TPR_1 PF00515.28 KDO25806.1 - 0.011 15.6 1.7 2 8.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25806.1 - 0.03 14.0 0.2 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 TPR repeat LRR_8 PF13855.6 KDO25806.1 - 0.42 10.4 5.5 9.8 6.0 4.0 3.3 2 1 1 3 3 3 0 Leucine rich repeat ArfGap PF01412.18 KDO25807.1 - 1.4e-32 112.2 0.0 2.5e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SCHIP-1 PF10148.9 KDO25807.1 - 0.045 13.4 0.1 0.045 13.4 0.1 1.8 2 1 1 3 3 3 0 Schwannomin-interacting protein 1 CEL_III_C PF18054.1 KDO25807.1 - 2.5 8.1 6.1 0.92 9.6 2.1 2.1 1 1 1 2 2 2 0 CEL-III C-terminal TonB_N PF16031.5 KDO25807.1 - 4.3 7.9 16.1 0.69 10.4 11.6 2.0 2 0 0 2 2 2 0 TonB polyproline region Rap_GAP PF02145.15 KDO25808.1 - 5.6e-53 179.3 0.0 9.7e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP RGS PF00615.19 KDO25808.1 - 3.6e-06 27.2 0.8 1.2e-05 25.6 0.4 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Edc3_linker PF16598.5 KDO25808.1 - 0.018 15.7 0.6 0.072 13.8 0.2 2.3 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 ApbA PF02558.16 KDO25808.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cytochrom_B561 PF03188.16 KDO25809.1 - 7.9e-36 123.2 11.4 7.9e-36 123.2 11.4 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 PAC2 PF09754.9 KDO25810.1 - 3.8e-12 46.7 0.0 9.5e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 PAC2 family LRR_6 PF13516.6 KDO25811.1 - 1.8e-38 127.3 50.5 4.6e-05 23.2 1.4 16.9 18 0 0 18 18 18 11 Leucine Rich repeat LRR_1 PF00560.33 KDO25811.1 - 2.8e-10 39.3 21.0 4.2 8.3 0.4 13.5 16 0 0 16 16 16 2 Leucine Rich Repeat LRR_4 PF12799.7 KDO25811.1 - 9.3e-10 38.6 24.4 1.6 9.3 0.0 10.0 7 4 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO25811.1 - 0.0002 21.0 36.5 0.096 12.5 1.4 10.0 7 5 0 7 7 7 3 Leucine rich repeat Ank_2 PF12796.7 KDO25812.1 - 7.4e-06 26.5 0.3 0.015 15.9 0.1 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO25812.1 - 0.00015 22.3 0.2 0.09 13.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO25812.1 - 0.00016 21.9 0.4 0.77 10.2 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25812.1 - 0.017 15.6 0.1 33 5.5 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat Lactonase PF10282.9 KDO25813.1 - 1.6e-83 280.9 0.0 1.8e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller LRR_6 PF13516.6 KDO25814.1 - 5.2e-19 66.6 2.7 5.4e-06 26.1 0.0 4.4 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 KDO25814.1 - 0.00035 20.9 3.0 0.26 11.8 0.1 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 KDO25814.1 - 0.13 13.0 0.3 1.2 9.9 0.0 2.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_1 PF00560.33 KDO25814.1 - 0.15 12.7 0.0 29 5.7 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat Pga1 PF10333.9 KDO25815.1 - 0.023 14.6 0.0 0.072 13.0 0.0 1.7 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator zf-C2H2 PF00096.26 KDO25816.1 - 1.1e-18 66.6 24.3 9.6e-05 22.6 2.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO25816.1 - 8.3e-16 57.6 23.0 6.6e-05 23.1 0.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain BET PF17035.5 KDO25816.1 - 1.2e-12 47.8 0.1 2.3e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation zf-C2H2_4 PF13894.6 KDO25816.1 - 1.9e-10 40.7 21.7 0.0086 16.8 1.6 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KDO25816.1 - 0.00012 22.2 13.1 0.00057 20.1 0.7 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO25816.1 - 0.00017 21.9 11.8 0.0094 16.3 0.9 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KDO25816.1 - 0.0028 18.3 8.5 0.27 11.9 2.6 2.3 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 KDO25816.1 - 0.0054 17.0 10.0 1.4 9.3 1.9 4.2 1 1 2 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KDO25816.1 - 0.16 12.1 8.2 1.1 9.3 0.1 3.5 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KDO25816.1 - 0.24 12.0 0.0 0.24 12.0 0.0 4.5 3 1 2 5 5 5 0 FOXP coiled-coil domain Kinesin PF00225.23 KDO25817.1 - 8.3e-103 343.8 0.0 8.3e-103 343.8 0.0 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KDO25817.1 - 2.4e-24 86.0 0.0 9.6e-24 84.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Spore_III_AB PF09548.10 KDO25817.1 - 1.2 9.2 5.8 3.4 7.7 4.6 2.5 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SLATT_5 PF18160.1 KDO25817.1 - 6.8 6.0 11.4 0.52 9.6 0.2 3.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3037 PF11236.8 KDO25817.1 - 7 7.1 8.4 6 7.3 2.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) HEAT PF02985.22 KDO25818.1 - 6.8e-13 47.7 13.2 0.0026 17.9 0.1 5.9 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 KDO25818.1 - 1e-05 25.8 9.1 0.85 10.1 0.1 5.0 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KDO25818.1 - 0.00013 22.4 14.8 0.47 11.0 0.5 5.3 5 1 1 6 6 6 4 HEAT-like repeat Cnd1 PF12717.7 KDO25818.1 - 0.0063 16.6 0.1 10 6.2 0.1 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KDO25818.1 - 0.024 14.9 0.0 0.56 10.6 0.0 2.7 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain EF_TS PF00889.19 KDO25819.1 - 4e-52 176.9 1.1 5.5e-52 176.4 1.1 1.2 1 0 0 1 1 1 1 Elongation factor TS TPR_1 PF00515.28 KDO25820.1 - 5.7e-10 38.6 0.9 0.0028 17.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25820.1 - 2.2e-09 36.7 0.2 0.0013 18.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25820.1 - 2e-08 34.6 2.9 6.6e-07 29.8 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO25820.1 - 4.2e-07 29.9 2.6 0.00048 20.1 0.1 3.6 1 1 2 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KDO25820.1 - 3e-06 27.4 1.2 0.0014 18.8 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25820.1 - 8.7e-06 25.6 2.6 0.013 15.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 KDO25820.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_7 PF13176.6 KDO25820.1 - 5.7e-05 22.9 0.1 0.91 9.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25820.1 - 0.00012 22.6 0.7 0.013 16.3 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25820.1 - 0.00025 21.2 8.4 0.00092 19.4 0.3 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KDO25820.1 - 0.00039 21.0 0.4 0.51 11.0 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25820.1 - 0.0021 17.9 0.8 2 8.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KDO25820.1 - 0.0048 16.9 4.8 0.12 12.3 0.5 2.6 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_17 PF13431.6 KDO25820.1 - 0.052 13.9 0.7 11 6.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25820.1 - 0.087 12.5 7.4 0.2 11.4 0.2 3.3 3 1 1 4 4 4 0 TPR repeat TPR_6 PF13174.6 KDO25820.1 - 0.11 13.2 0.3 2.9 8.7 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat SAP30_Sin3_bdg PF13867.6 KDO25821.1 - 7.2e-13 48.7 0.6 1.2e-12 47.9 0.1 1.7 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 KDO25821.1 - 2.7e-06 27.2 6.5 2.7e-06 27.2 6.5 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KDO25821.1 - 0.59 9.7 5.9 0.093 12.3 1.7 2.0 2 1 0 2 2 2 0 PHD-finger Peptidase_S9_N PF02897.15 KDO25822.1 - 4.8e-58 196.9 0.0 6.4e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KDO25822.1 - 8.4e-48 162.6 0.1 2e-47 161.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KDO25822.1 - 0.0062 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 KDO25822.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold R2K_2 PF18299.1 KDO25822.1 - 0.12 12.3 0.1 0.33 10.8 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 DUF4945 PF16303.5 KDO25822.1 - 0.22 11.4 0.6 0.69 9.9 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4945) Pkinase PF00069.25 KDO25824.1 - 4.8e-69 232.7 0.0 6e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25824.1 - 1.7e-36 125.8 0.0 2.3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25824.1 - 1.4e-08 34.4 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO25824.1 - 0.13 12.2 0.0 0.6 10.0 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO25824.1 - 0.16 10.8 0.4 0.26 10.2 0.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain LRR_8 PF13855.6 KDO25825.1 - 2e-44 149.2 39.8 8.9e-10 38.2 0.6 8.1 4 2 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 KDO25825.1 - 4.2e-38 128.7 32.4 7.6e-07 29.4 2.6 9.0 3 2 7 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO25825.1 - 9.2e-14 51.3 9.1 8.4e-05 22.1 0.2 4.1 1 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KDO25825.1 - 6.1e-11 41.3 34.8 6.4 7.7 0.1 14.5 15 0 0 15 15 15 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO25825.1 - 0.0081 16.1 27.0 3.9 7.8 0.0 9.5 10 1 1 11 11 11 2 Leucine Rich repeat CSTF_C PF14304.6 KDO25825.1 - 0.14 11.8 3.2 66 3.2 0.0 4.4 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal EF-hand_6 PF13405.6 KDO25826.1 - 8.5e-10 37.8 1.7 0.0013 18.5 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KDO25826.1 - 1.1e-09 37.1 1.8 0.00021 20.6 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO25826.1 - 3.7e-08 33.1 0.9 0.0069 16.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 KDO25826.1 - 2.5e-07 31.0 0.4 2.5e-07 31.0 0.4 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO25826.1 - 0.003 17.0 1.2 0.058 12.9 0.2 2.7 2 0 0 2 2 2 1 EF hand DUF948 PF06103.11 KDO25826.1 - 0.053 13.8 0.3 10 6.4 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EF-hand_10 PF14788.6 KDO25826.1 - 0.13 12.2 1.0 1.3 8.9 0.5 2.5 2 0 0 2 2 2 0 EF hand Arg_decarbox_C PF17944.1 KDO25826.1 - 0.19 12.3 1.9 38 4.9 0.0 4.1 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension Peptidase_S10 PF00450.22 KDO25827.1 - 4e-117 392.2 0.0 4.8e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CRAL_TRIO PF00650.20 KDO25828.1 - 5e-31 107.6 0.1 9.8e-31 106.6 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain FYVE PF01363.21 KDO25828.1 - 4.7e-12 45.9 3.3 1e-11 44.8 3.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger CRAL_TRIO_2 PF13716.6 KDO25828.1 - 8.6e-06 25.9 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3362 PF11842.8 KDO25828.1 - 0.04 14.2 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) FYVE_2 PF02318.16 KDO25828.1 - 0.22 11.8 4.1 0.23 11.7 2.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger 2OG-FeII_Oxy_2 PF13532.6 KDO25829.1 - 6.4e-18 65.6 0.0 2.1e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KDO25829.1 - 9.9e-14 51.8 0.1 2.4e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO25829.1 - 3.4e-11 43.7 0.1 8.9e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO25829.1 - 1.2e-07 31.7 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO25829.1 - 3e-07 31.1 0.1 6.8e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 KDO25829.1 - 3.3e-06 26.8 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.6 KDO25829.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO25829.1 - 0.00038 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KDO25829.1 - 0.00068 18.6 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 KDO25829.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RRM_occluded PF16842.5 KDO25829.1 - 0.039 13.8 0.2 0.077 12.9 0.2 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4523 PF15023.6 KDO25829.1 - 0.076 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Rhamnogal_lyase PF06045.11 KDO25829.1 - 0.11 11.8 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Rhamnogalacturonate lyase family RRM_5 PF13893.6 KDO25829.1 - 0.11 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc24 PF08286.11 KDO25830.1 - 2e-07 31.2 0.1 3.2e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 Spc24 subunit of Ndc80 Spc7 PF08317.11 KDO25830.1 - 8.3e-05 21.6 3.0 0.00011 21.2 3.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein 23S_rRNA_IVP PF05635.11 KDO25830.1 - 0.015 15.6 2.1 0.025 14.8 1.9 1.5 1 1 0 1 1 1 0 23S rRNA-intervening sequence protein PI3K_P85_iSH2 PF16454.5 KDO25830.1 - 0.078 12.6 8.5 0.13 11.9 7.4 1.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Glucan_synthase PF02364.15 KDO25830.1 - 0.094 10.9 0.6 0.11 10.7 0.6 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Cauli_AT PF03233.13 KDO25830.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein DUF1515 PF07439.11 KDO25830.1 - 0.13 12.3 1.5 0.25 11.4 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF724 PF05266.14 KDO25830.1 - 0.62 9.9 8.1 0.54 10.0 6.5 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 KDO25830.1 - 1.7 8.8 12.5 4.9 7.4 12.5 1.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 KDO25830.1 - 2.4 6.6 9.9 3.1 6.2 9.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 KDO25830.1 - 5 7.7 14.8 8.6 6.9 14.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Abhydrolase_1 PF00561.20 KDO25831.1 - 3.5e-29 102.2 0.0 4.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO25831.1 - 0.00013 22.7 0.1 0.00017 22.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO25831.1 - 0.00087 18.6 0.0 0.003 16.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KDO25831.1 - 0.0058 16.3 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KDO25831.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Pro_isomerase PF00160.21 KDO25832.1 - 1.6e-46 158.5 0.0 1.8e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_14 PF13428.6 KDO25833.1 - 0.055 14.3 1.7 8.6 7.5 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat STAT6_C PF14596.6 KDO25833.1 - 0.087 12.8 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 STAT6 C-terminal SicP-binding PF09119.10 KDO25834.1 - 0.073 13.1 0.9 1.5 8.9 0.1 2.3 1 1 1 2 2 2 0 SicP binding WD40 PF00400.32 KDO25835.1 - 5.1e-09 36.6 33.8 0.0013 19.5 0.1 12.3 15 0 0 15 15 15 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25835.1 - 3.4e-05 24.1 1.8 0.82 10.0 0.0 6.7 6 2 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO25835.1 - 0.0018 17.0 0.1 0.02 13.6 0.0 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Frtz PF11768.8 KDO25835.1 - 0.017 13.5 0.1 0.017 13.5 0.1 3.3 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF667 PF05018.13 KDO25836.1 - 2.1e-29 102.6 0.0 2.5e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) FYVE PF01363.21 KDO25837.1 - 4.3e-14 52.4 13.8 9.8e-14 51.3 13.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO25837.1 - 0.00077 19.7 6.6 0.0026 18.0 6.6 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 KDO25837.1 - 0.03 14.7 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 GAF domain PH PF00169.29 KDO25839.1 - 8.5e-08 32.7 0.0 2.1e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO25839.1 - 0.077 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain zf-CCHC_2 PF13696.6 KDO25840.1 - 2.6e-09 36.7 1.3 5.3e-09 35.7 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KDO25840.1 - 6.8e-05 22.6 11.4 0.00012 21.8 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KDO25840.1 - 0.0069 16.4 0.2 0.015 15.4 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 KDO25840.1 - 0.0083 16.3 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 U-box domain Siva PF05458.12 KDO25840.1 - 0.034 13.8 0.2 0.066 12.9 0.2 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF3914 PF13053.6 KDO25840.1 - 0.14 12.6 1.0 0.39 11.1 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) zf-C3HC4 PF00097.25 KDO25840.1 - 0.23 11.4 11.5 0.46 10.4 11.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO25840.1 - 0.32 11.0 11.6 0.68 9.9 11.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO25840.1 - 0.46 10.4 18.1 0.02 14.7 12.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO25840.1 - 1.4 8.8 13.2 7.2 6.6 13.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KDO25840.1 - 6 7.1 10.5 13 6.0 10.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ILVD_EDD PF00920.21 KDO25841.1 - 4.6e-214 711.8 0.1 5.3e-214 711.6 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 KDO25841.1 - 0.0092 16.2 0.4 0.69 10.2 0.0 3.7 4 0 0 4 4 4 1 FeoA domain ILVD_EDD PF00920.21 KDO25842.1 - 6.1e-215 714.7 1.6 7.1e-215 714.5 1.6 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 KDO25842.1 - 0.0041 17.3 0.4 6.3 7.1 0.0 3.3 4 0 0 4 4 4 2 FeoA domain ZZ PF00569.17 KDO25843.1 - 9.5e-07 28.5 6.5 1.7e-06 27.7 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Bap31_Bap29_C PF18035.1 KDO25843.1 - 0.12 12.4 0.4 6.3 6.9 0.1 2.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Borrelia_P83 PF05262.11 KDO25843.1 - 1.2 7.5 6.0 1.9 6.9 6.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Csm1_N PF18504.1 KDO25843.1 - 1.6 9.1 16.4 3.2 8.1 0.5 3.7 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF641 PF04859.12 KDO25843.1 - 2.3 8.5 12.2 0.093 13.1 3.3 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) CREPT PF16566.5 KDO25843.1 - 2.9 8.1 12.3 2.3 8.4 6.5 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 KDO25843.1 - 3 7.3 13.6 5.8 6.4 13.6 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KxDL PF10241.9 KDO25843.1 - 3.9 7.8 9.4 0.78 10.1 1.7 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF4559 PF15112.6 KDO25843.1 - 5.5 6.6 7.9 8.7 5.9 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FtsJ PF01728.19 KDO25844.1 - 4e-09 36.8 0.0 5.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KDO25844.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MIF4G PF02854.19 KDO25845.1 - 1.3e-50 172.0 0.0 7.5e-24 84.6 0.0 3.9 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KDO25845.1 - 3.1e-17 63.6 1.2 3.1e-17 63.6 1.2 2.2 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Nop14 PF04147.12 KDO25845.1 - 1.2 7.3 18.0 0.68 8.1 12.8 2.4 2 0 0 2 2 2 0 Nop14-like family LRR_8 PF13855.6 KDO25846.1 - 4.7e-16 58.3 16.7 3.3e-07 30.0 0.4 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KDO25846.1 - 9.3e-13 48.2 8.5 0.00021 21.6 1.0 4.4 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO25846.1 - 0.15 12.7 10.0 93 4.2 0.2 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat Oxidored_molyb PF00174.19 KDO25847.1 - 2.3e-53 180.3 0.0 3.6e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KDO25847.1 - 6.5e-42 142.8 0.3 1.1e-41 142.0 0.3 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KDO25847.1 - 1.6e-12 47.4 0.1 2.9e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KDO25847.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.1 3 0 0 3 3 3 0 BNR/Asp-box repeat PH PF00169.29 KDO25848.1 - 2.2e-09 37.8 0.1 3.8e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO25848.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KDO25848.1 - 0.04 14.4 1.0 0.14 12.6 1.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain IGR PF09597.10 KDO25848.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif PH PF00169.29 KDO25849.1 - 0.019 15.5 0.0 0.043 14.3 0.0 1.6 1 1 0 1 1 1 0 PH domain Glyoxalase PF00903.25 KDO25849.1 - 0.11 12.8 0.2 6.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WW PF00397.26 KDO25850.1 - 0.0038 17.3 0.6 0.0084 16.2 0.6 1.6 1 0 0 1 1 1 1 WW domain Pea-VEAacid PF08111.11 KDO25850.1 - 0.28 11.6 1.6 1.4 9.4 0.1 2.8 2 0 0 2 2 2 0 Pea-VEAacid family DUF4200 PF13863.6 KDO25851.1 - 5.3e-32 110.7 23.4 5.3e-32 110.7 23.4 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) BAR_3 PF16746.5 KDO25851.1 - 1.2e-05 25.1 9.9 1.2e-05 25.1 9.9 2.0 1 1 1 2 2 2 1 BAR domain of APPL family WWE PF02825.20 KDO25851.1 - 0.013 16.0 1.1 6.3 7.5 0.6 2.7 2 0 0 2 2 2 0 WWE domain HK97-gp10_like PF04883.12 KDO25851.1 - 0.072 14.1 0.2 0.072 14.1 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF4349 PF14257.6 KDO25851.1 - 1.1 8.6 10.5 0.51 9.7 1.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Mei5_like PF17021.5 KDO25851.1 - 2.8 8.0 11.2 1.9 8.5 8.7 2.1 1 1 0 1 1 1 0 Putative double-strand recombination repair-like XPG_N PF00752.17 KDO25852.1 - 5.8e-28 97.3 0.0 1.3e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KDO25852.1 - 1.4e-26 92.7 0.0 4e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KDO25852.1 - 0.00023 20.7 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 XPG domain containing HHH_2 PF12826.7 KDO25852.1 - 0.18 11.9 0.2 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF2052 PF09747.9 KDO25852.1 - 4.3 7.4 15.4 13 5.8 15.4 1.8 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MIF4G PF02854.19 KDO25853.1 - 7.4e-48 163.0 1.3 2.3e-31 109.1 0.1 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 KDO25853.1 - 3e-08 33.6 0.7 1e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 MA3 domain HTH_22 PF13309.6 KDO25853.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 HTH domain Coilin_N PF15862.5 KDO25855.1 - 1e-13 51.3 5.8 3.7e-13 49.5 0.0 3.0 3 0 0 3 3 3 1 Coilin N-terminus SR-25 PF10500.9 KDO25855.1 - 0.00078 19.1 9.3 0.00078 19.1 9.3 2.9 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF455 PF04305.14 KDO25856.1 - 1.4e-67 227.9 0.0 2.1e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Glyco_trans_1_4 PF13692.6 KDO25856.1 - 2.6e-18 66.7 0.0 5.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 NAD_binding_4 PF07993.12 KDO25857.1 - 1.4e-71 240.7 0.0 2e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 KDO25857.1 - 4.6e-21 74.9 0.0 9.2e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 KDO25857.1 - 1.2e-13 51.1 0.1 2.3e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KDO25857.1 - 0.00022 20.7 0.0 0.00081 18.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KDO25857.1 - 0.00046 19.3 0.1 0.032 13.2 0.0 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KDO25857.1 - 0.0022 17.5 0.4 0.052 12.9 0.4 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF433 PF04255.14 KDO25857.1 - 0.11 12.3 0.1 3.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF433) Polysacc_synt_2 PF02719.15 KDO25857.1 - 0.19 10.9 0.4 1.2 8.3 0.3 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein BicD PF09730.9 KDO25858.1 - 0.032 12.7 0.1 0.034 12.6 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D SKA2 PF16740.5 KDO25858.1 - 0.09 12.6 0.3 0.43 10.4 0.0 2.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 KDO25858.1 - 0.096 11.5 0.2 3 6.7 0.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 KDO25858.1 - 0.098 13.0 0.4 1 9.7 0.0 2.7 2 1 2 4 4 4 0 Csm1 N-terminal domain Tropomyosin PF00261.20 KDO25858.1 - 0.1 11.9 0.2 0.64 9.4 0.2 2.0 1 1 0 1 1 1 0 Tropomyosin CENP-F_leu_zip PF10473.9 KDO25859.1 - 0.0021 18.1 6.5 0.0021 18.1 6.5 1.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GvpL_GvpF PF06386.11 KDO25859.1 - 0.0043 17.0 3.9 0.005 16.8 3.9 1.2 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF DUF4201 PF13870.6 KDO25859.1 - 0.0056 16.4 4.7 0.01 15.6 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) APG6_N PF17675.1 KDO25859.1 - 0.0068 16.9 7.5 0.011 16.3 7.5 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region CorA PF01544.18 KDO25859.1 - 0.013 14.8 2.1 0.018 14.4 2.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 KDO25859.1 - 0.016 14.1 3.7 0.023 13.6 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KDO25859.1 - 0.029 14.5 1.3 0.039 14.1 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KDO25859.1 - 0.037 13.1 3.4 0.049 12.7 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KDO25859.1 - 0.072 12.4 8.3 0.055 12.8 5.5 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPD52 PF04201.15 KDO25859.1 - 0.092 12.4 1.5 0.14 11.8 1.5 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DUF1664 PF07889.12 KDO25859.1 - 0.18 11.8 2.3 0.16 12.0 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KDO25859.1 - 0.22 11.3 4.8 0.13 12.1 3.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 KDO25859.1 - 0.5 10.8 6.1 1.6 9.2 6.1 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 KDO25859.1 - 0.76 10.3 9.3 0.37 11.3 5.4 2.3 2 1 1 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 KDO25859.1 - 4.4 7.2 6.2 2.1 8.2 3.2 2.0 2 0 0 2 2 2 0 Septum formation initiator NAD_binding_4 PF07993.12 KDO25860.1 - 1.3e-17 63.8 0.0 1.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KDO25860.1 - 0.014 14.4 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KDO25860.1 - 0.024 14.1 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KDO25860.1 - 0.036 14.5 0.0 0.071 13.6 0.0 1.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KDO25860.1 - 0.069 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KDO25860.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Spc7 PF08317.11 KDO25861.1 - 6.2e-05 22.0 3.6 8.6e-05 21.6 3.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 KDO25861.1 - 0.00047 19.4 6.9 0.00092 18.4 6.9 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 KDO25861.1 - 0.00048 19.8 8.1 0.00069 19.3 7.4 1.6 1 1 1 2 2 2 1 Intermediate filament protein Cast PF10174.9 KDO25861.1 - 0.00074 17.9 4.0 0.0011 17.4 4.0 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone CCDC154 PF15450.6 KDO25861.1 - 0.0014 17.3 2.3 0.0014 17.3 2.3 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 154 DUF812 PF05667.11 KDO25861.1 - 0.0052 15.7 3.8 0.0052 15.7 3.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Fez1 PF06818.15 KDO25861.1 - 0.0076 16.7 4.7 0.0076 16.7 4.7 1.6 2 0 0 2 2 1 1 Fez1 BAR PF03114.18 KDO25861.1 - 0.01 15.5 5.1 0.017 14.8 5.1 1.3 1 0 0 1 1 1 0 BAR domain BRE1 PF08647.11 KDO25861.1 - 0.013 15.6 6.6 0.027 14.5 6.6 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase KLRAQ PF10205.9 KDO25861.1 - 0.018 15.3 1.4 0.018 15.3 1.4 1.7 2 0 0 2 2 1 0 Predicted coiled-coil domain-containing protein CheZ PF04344.13 KDO25861.1 - 0.026 14.5 2.3 0.049 13.5 2.3 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Med9 PF07544.13 KDO25861.1 - 0.028 14.5 2.4 0.053 13.6 1.7 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 KDO25861.1 - 0.046 12.4 1.5 0.059 12.0 1.5 1.1 1 0 0 1 1 1 0 AAA domain Pex19 PF04614.12 KDO25861.1 - 0.053 13.3 5.2 0.092 12.5 5.2 1.3 1 0 0 1 1 1 0 Pex19 protein family UPF0242 PF06785.11 KDO25861.1 - 0.055 13.6 2.4 0.11 12.6 2.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KDO25861.1 - 0.058 13.2 7.4 0.098 12.5 7.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mod_r PF07200.13 KDO25861.1 - 0.079 13.1 6.0 0.14 12.3 5.3 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Herpes_UL6 PF01763.16 KDO25861.1 - 0.1 11.1 1.6 0.14 10.6 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like PI3K_P85_iSH2 PF16454.5 KDO25861.1 - 0.2 11.2 8.5 0.019 14.6 3.9 1.6 2 0 0 2 2 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain 4HB_MCP_1 PF12729.7 KDO25861.1 - 0.27 10.8 4.1 0.47 10.0 4.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ATG16 PF08614.11 KDO25861.1 - 0.27 11.4 15.8 0.021 15.1 8.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 KDO25861.1 - 0.32 11.3 4.7 0.94 9.7 4.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 KDO25861.1 - 0.32 10.2 2.9 0.61 9.3 2.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Baculo_PEP_C PF04513.12 KDO25861.1 - 0.4 10.7 1.3 15 5.6 1.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mu-like_Pro PF10123.9 KDO25861.1 - 0.47 9.9 4.6 0.79 9.2 4.6 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein FlaC_arch PF05377.11 KDO25861.1 - 0.65 10.4 4.8 0.72 10.3 1.2 2.7 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 KDO25861.1 - 0.72 10.3 6.2 0.34 11.4 1.0 2.6 2 1 1 3 3 2 0 Cell division protein ZapB Phage_GP20 PF06810.11 KDO25861.1 - 0.84 9.4 4.9 1.8 8.4 4.8 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 HSP70 PF00012.20 KDO25861.1 - 1.3 7.2 4.5 1.8 6.7 4.5 1.1 1 0 0 1 1 1 0 Hsp70 protein TMF_DNA_bd PF12329.8 KDO25861.1 - 1.3 9.0 6.5 12 6.0 2.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 KDO25861.1 - 2.2 8.9 7.4 0.58 10.8 3.6 2.1 2 1 0 2 2 1 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 KDO25861.1 - 3 8.5 14.0 0.046 14.3 4.5 2.6 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KDO25861.1 - 3.1 8.3 8.9 8.4 6.9 8.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 KDO25861.1 - 5.5 6.8 10.2 0.82 9.5 6.5 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF724) DUF4795 PF16043.5 KDO25862.1 - 4.2e-05 23.3 4.8 0.0013 18.3 4.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Syntaxin_2 PF14523.6 KDO25862.1 - 0.00013 22.2 3.8 0.0044 17.4 0.3 2.6 1 1 2 3 3 3 1 Syntaxin-like protein Cep57_CLD_2 PF14197.6 KDO25862.1 - 0.0044 17.1 6.5 0.049 13.7 1.7 2.7 1 1 0 2 2 2 1 Centrosome localisation domain of PPC89 ApoLp-III PF07464.11 KDO25862.1 - 0.027 14.6 2.4 0.048 13.7 2.4 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KDO25862.1 - 0.05 11.6 1.2 0.05 11.6 1.2 1.2 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 KDO25862.1 - 0.054 13.8 3.6 0.39 11.1 3.6 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 KDO25862.1 - 0.055 13.5 4.6 0.23 11.5 2.6 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pro_dh-DNA_bdg PF14850.6 KDO25862.1 - 0.073 13.6 0.2 3 8.4 0.0 2.1 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase DHHA1 PF02272.19 KDO25862.1 - 0.077 13.4 0.5 0.1 13.0 0.5 1.2 1 0 0 1 1 1 0 DHHA1 domain Phage_T7_Capsid PF05396.11 KDO25862.1 - 0.09 13.1 0.2 0.19 12.1 0.2 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein DUF2383 PF09537.10 KDO25862.1 - 0.13 12.6 2.2 0.69 10.3 0.5 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF2383) DNA_pack_N PF02500.15 KDO25862.1 - 0.14 11.9 0.4 0.16 11.7 0.4 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus DUF4407 PF14362.6 KDO25862.1 - 0.17 11.2 3.0 0.22 10.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 KDO25862.1 - 0.32 9.5 3.5 0.37 9.3 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CHD5 PF04420.14 KDO25862.1 - 0.43 10.4 1.8 0.86 9.4 0.2 2.0 2 0 0 2 2 2 0 CHD5-like protein Fzo_mitofusin PF04799.13 KDO25862.1 - 0.71 9.4 7.7 1 8.9 1.7 2.8 1 1 2 3 3 3 0 fzo-like conserved region GIT_CC PF16559.5 KDO25862.1 - 1 9.3 5.5 3.5 7.6 0.3 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HSCB_C PF07743.13 KDO25862.1 - 1.2 9.7 4.5 3.7 8.1 3.6 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Spc7 PF08317.11 KDO25862.1 - 2.8 6.7 7.6 9.3 5.0 5.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein bZIP_2 PF07716.15 KDO25862.1 - 8.6 6.5 8.4 4.4 7.5 0.4 3.0 2 1 1 3 3 3 0 Basic region leucine zipper DUF4457 PF14652.6 KDO25864.1 - 4e-133 443.7 0.0 1.4e-92 310.4 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 KDO25864.1 - 0.018 15.0 0.0 26 4.8 0.0 3.8 4 0 0 4 4 4 0 Sad1 / UNC-like C-terminal Peptidase_C1_2 PF03051.15 KDO25865.1 - 2.2e-159 530.9 0.1 2.5e-159 530.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO25865.1 - 2.4e-08 34.3 1.6 3.2e-05 24.1 0.2 2.5 2 1 0 2 2 2 2 Papain family cysteine protease Peptidase_C1 PF00112.23 KDO25866.1 - 7.5e-36 124.3 0.0 9.9e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease BAR PF03114.18 KDO25867.1 - 3.1e-14 53.2 12.5 2.8e-13 50.1 12.5 1.9 1 1 0 1 1 1 1 BAR domain DUF2203 PF09969.9 KDO25867.1 - 0.14 12.9 4.6 1.4 9.7 3.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3899 PF13038.6 KDO25867.1 - 0.19 12.3 0.0 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) EMC3_TMCO1 PF01956.16 KDO25867.1 - 2.5 7.8 5.7 4.1 7.1 5.7 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Hrs_helical PF12210.8 KDO25867.1 - 9.6 6.8 12.3 2.4 8.7 8.4 2.0 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pkinase PF00069.25 KDO25868.1 - 3.4e-75 252.8 0.0 9e-75 251.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25868.1 - 9.2e-52 175.9 0.0 1.5e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO25868.1 - 3.5e-05 22.8 0.0 6.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO25868.1 - 0.00021 20.7 0.1 0.0014 18.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KDO25868.1 - 0.0027 17.1 0.1 0.0065 15.8 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family V-ATPase_H_C PF11698.8 KDO25868.1 - 0.0048 17.0 0.0 0.052 13.7 0.0 2.7 2 0 0 2 2 2 1 V-ATPase subunit H LisH_TPL PF17814.1 KDO25868.1 - 0.11 12.2 0.4 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 LisH-like dimerisation domain Arm PF00514.23 KDO25868.1 - 0.19 11.8 4.1 34 4.7 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RYDR_ITPR PF01365.21 KDO25868.1 - 0.55 9.6 7.1 0.5 9.7 0.7 3.2 3 1 0 3 3 3 0 RIH domain DUF4757 PF15949.5 KDO25868.1 - 2.5 8.5 4.7 3.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Glyco_hydro_47 PF01532.20 KDO25869.1 - 6.5e-94 315.4 0.0 6.9e-81 272.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 FKBP_C PF00254.28 KDO25870.1 - 4e-25 88.0 0.0 4.6e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 KDO25870.1 - 0.21 11.7 0.0 0.26 11.4 0.0 1.4 1 1 0 1 1 1 0 BDBT FKBP like N-terminal VWA_N PF08399.11 KDO25871.1 - 0.089 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 VWA N-terminal JIP_LZII PF16471.5 KDO25872.1 - 0.003 17.7 4.7 0.0041 17.3 3.2 1.9 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II Mod_r PF07200.13 KDO25872.1 - 0.0082 16.3 3.0 0.019 15.1 3.0 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.8 KDO25872.1 - 0.027 14.4 6.0 0.057 13.4 6.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4517 PF15006.6 KDO25872.1 - 0.075 13.2 0.3 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4517) DivIC PF04977.15 KDO25872.1 - 0.4 10.5 2.7 0.64 9.8 0.8 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 KDO25872.1 - 0.55 9.5 6.3 0.88 8.8 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KDO25872.1 - 0.61 10.3 11.8 0.087 13.0 7.2 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KDO25872.1 - 1 10.0 5.9 11 6.7 3.1 2.9 2 1 0 2 2 2 0 SlyX bZIP_2 PF07716.15 KDO25872.1 - 1.4 9.1 5.0 0.67 10.1 0.3 2.6 3 0 0 3 3 3 0 Basic region leucine zipper ADIP PF11559.8 KDO25872.1 - 1.9 8.5 10.6 5.8 7.0 10.6 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KDO25872.1 - 2.7 8.5 10.0 8.4 6.9 10.0 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Rootletin PF15035.6 KDO25872.1 - 5.4 7.0 10.7 13 5.7 10.8 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 KDO25872.1 - 6.1 7.4 10.5 49 4.5 9.7 2.4 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KDO25872.1 - 8.2 7.1 9.7 11 6.7 3.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA RT_RNaseH PF17917.1 KDO25873.1 - 1.1e-11 45.0 0.0 9.1e-10 38.8 0.0 2.5 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KDO25873.1 - 1.7e-05 24.8 0.0 0.00015 21.8 0.0 2.3 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_C74 PF12387.8 KDO25873.1 - 0.17 11.3 0.1 0.67 9.4 0.0 1.8 1 1 1 2 2 2 0 Pestivirus NS2 peptidase Methyltransf_11 PF08241.12 KDO25875.1 - 1.3e-08 35.4 0.1 5.2e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO25875.1 - 1.3e-06 29.0 0.6 4.2e-05 24.2 0.2 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO25875.1 - 0.027 14.3 0.0 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF179 PF02622.15 KDO25876.1 - 8.7e-27 94.0 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 COX17 PF05051.13 KDO25877.1 - 6.6e-19 68.0 5.8 7.7e-19 67.8 5.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) E1-E2_ATPase PF00122.20 KDO25879.1 - 3.4e-18 65.8 0.1 4.4e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KDO25879.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HMG_box PF00505.19 KDO25880.1 - 2.5e-39 133.5 17.7 1.1e-20 73.8 6.9 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KDO25880.1 - 1.2e-26 93.1 16.6 2.2e-13 50.6 1.9 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 KDO25880.1 - 0.00049 20.0 19.6 0.024 14.6 2.7 3.2 2 2 1 3 3 3 2 HMG (high mobility group) box 5 DUF823 PF05689.11 KDO25880.1 - 0.13 12.0 4.6 1.2 8.9 0.1 2.9 2 1 1 3 3 3 0 Salmonella repeat of unknown function (DUF823) Tombus_P33 PF08500.10 KDO25880.1 - 0.29 11.1 1.9 0.3 11.1 0.3 1.8 1 1 1 2 2 2 0 Tombusvirus p33 PHF5 PF03660.14 KDO25881.1 - 7.8e-51 170.6 10.1 8.7e-51 170.5 10.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KDO25881.1 - 0.012 13.5 5.6 0.013 13.4 5.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KDO25881.1 - 0.23 11.5 11.3 2.7 8.1 9.8 2.4 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KDO25881.1 - 0.25 11.7 13.7 0.44 10.9 2.4 2.4 1 1 1 2 2 2 0 C1 domain PHD PF00628.29 KDO25881.1 - 1.8 8.5 11.2 2.8 7.9 9.4 2.5 2 1 0 2 2 2 0 PHD-finger RecR PF02132.15 KDO25881.1 - 5.4 6.7 12.7 0.96 9.1 0.5 3.1 3 0 0 3 3 3 0 RecR protein Efg1 PF10153.9 KDO25882.1 - 1.7e-26 92.8 9.4 1.7e-26 92.8 9.4 2.8 3 0 0 3 3 3 1 rRNA-processing protein Efg1 MDFI PF15316.6 KDO25882.1 - 3 7.9 11.4 1.9 8.6 6.0 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Nop53 PF07767.11 KDO25882.1 - 4.9 6.4 35.9 0.42 10.0 18.1 2.1 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 KDO25883.1 - 1.2e-56 192.1 0.0 1.4e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25883.1 - 1.9e-26 92.9 0.0 2.5e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO25883.1 - 3.6e-07 29.7 0.0 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO25883.1 - 9.1e-06 25.4 0.1 1.6e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KDO25883.1 - 9.6e-06 25.7 0.2 0.00028 20.9 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO25883.1 - 1.3e-05 24.7 0.0 2.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like WaaY PF06176.11 KDO25883.1 - 0.0021 17.7 0.2 0.014 15.0 0.1 1.9 1 1 1 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KDO25883.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 KDO25883.1 - 0.19 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Topoisom_I PF01028.20 KDO25884.1 - 0.0014 17.9 0.6 0.0014 17.9 0.6 2.9 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core HTH_1 PF00126.27 KDO25884.1 - 0.088 12.8 1.6 1.6 8.7 0.1 2.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF1484 PF07363.11 KDO25884.1 - 0.33 12.0 0.1 0.33 12.0 0.1 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1484) XhlA PF10779.9 KDO25884.1 - 0.71 10.1 9.3 1.3 9.3 0.0 3.4 3 0 0 3 3 3 0 Haemolysin XhlA DUF5600 PF18150.1 KDO25885.1 - 1.5e-40 138.0 1.8 3.4e-40 136.9 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 KDO25885.1 - 4.7e-16 58.4 2.6 9.5e-16 57.4 2.6 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KDO25885.1 - 1.9e-15 57.3 0.0 2.2e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EF-hand_4 PF12763.7 KDO25885.1 - 2.7e-10 40.1 0.3 2.8e-09 36.8 0.0 2.7 4 0 0 4 4 4 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 KDO25885.1 - 3.7e-10 39.9 0.0 1e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KDO25885.1 - 1.8e-05 23.9 0.6 8.6e-05 21.8 0.6 2.2 1 0 0 1 1 1 1 EF hand Gtr1_RagA PF04670.12 KDO25885.1 - 0.00029 20.3 0.0 0.00061 19.2 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KDO25885.1 - 0.00075 19.7 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KDO25885.1 - 0.0016 18.1 0.0 0.0048 16.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 KDO25885.1 - 0.0024 17.6 0.6 0.016 15.1 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain FeoB_N PF02421.18 KDO25885.1 - 0.0068 15.9 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KDO25885.1 - 0.0068 15.8 0.0 0.066 12.5 0.0 2.2 2 0 0 2 2 2 1 AIG1 family EF-hand_7 PF13499.6 KDO25885.1 - 0.0084 16.5 0.3 0.093 13.2 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO25885.1 - 0.015 14.8 0.3 0.06 12.9 0.3 2.1 1 0 0 1 1 1 0 EF hand Ras PF00071.22 KDO25885.1 - 0.027 14.1 0.3 8.2 6.0 0.0 3.1 3 0 0 3 3 3 0 Ras family RsgA_GTPase PF03193.16 KDO25885.1 - 0.059 13.3 0.0 9.7 6.1 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase Cullin PF00888.22 KDO25886.1 - 2e-187 624.6 0.2 2.7e-187 624.2 0.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KDO25886.1 - 5.4e-28 96.8 1.7 1.6e-27 95.3 1.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain MarR_2 PF12802.7 KDO25886.1 - 0.0074 16.1 0.6 0.69 9.8 0.3 2.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 KDO25886.1 - 0.009 15.5 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding MarR PF01047.22 KDO25886.1 - 0.027 14.4 0.7 0.97 9.4 0.1 3.0 3 0 0 3 3 3 0 MarR family Peptidase_C48 PF02902.19 KDO25887.1 - 0.0025 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Syntaxin PF00804.25 KDO25887.1 - 0.032 13.9 0.4 0.069 12.8 0.4 1.5 1 0 0 1 1 1 0 Syntaxin DUF1500 PF07389.12 KDO25887.1 - 0.11 12.5 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Phage_holin_3_6 PF07332.11 KDO25888.1 - 0.041 13.9 0.7 0.041 13.9 0.7 2.0 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4579 PF15158.6 KDO25888.1 - 0.17 11.6 2.9 0.25 11.1 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) HlyIII PF03006.20 KDO25888.1 - 0.44 10.2 9.8 0.55 9.9 5.7 2.3 2 1 0 2 2 2 0 Haemolysin-III related Promethin PF16015.5 KDO25888.1 - 1 9.3 10.1 6 6.8 1.1 2.8 2 0 0 2 2 2 0 Promethin DUF2070 PF09843.9 KDO25888.1 - 6.8 4.9 8.9 10 4.3 8.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) COPI_assoc PF08507.10 KDO25889.1 - 2.4e-19 69.7 8.3 3e-19 69.4 8.3 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3784 PF12650.7 KDO25889.1 - 0.11 12.7 8.1 0.12 12.6 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) DHHC PF01529.20 KDO25889.1 - 0.37 10.9 5.4 0.26 11.4 3.7 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase NiFe_hyd_3_EhaA PF17367.2 KDO25889.1 - 1.3 9.2 6.6 0.25 11.5 1.0 2.2 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A TPR_MLP1_2 PF07926.12 KDO25890.1 - 1.1e-10 41.6 19.3 1.1e-10 41.6 19.3 14.3 5 3 8 14 14 14 5 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 KDO25890.1 - 1.8e-05 24.4 4.6 0.093 12.6 0.0 6.3 4 0 0 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4677 PF15726.5 KDO25890.1 - 1.4 9.0 8.7 2.8 8.1 0.6 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4677) TPR_17 PF13431.6 KDO25891.1 - 3.1e-21 74.2 8.4 0.00093 19.4 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25891.1 - 1.5e-15 56.0 11.3 0.012 15.7 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25891.1 - 1.9e-15 55.9 7.0 0.0011 18.7 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25891.1 - 3.6e-15 54.8 3.7 0.0059 16.7 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25891.1 - 1.2e-09 38.2 16.1 0.55 11.2 0.0 7.2 2 1 5 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25891.1 - 3.8e-08 32.8 5.0 5.4 7.3 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25891.1 - 5.5e-08 33.0 21.4 0.024 14.9 0.0 5.8 3 1 4 7 7 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25891.1 - 3.2e-07 30.9 13.7 0.0019 18.8 0.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25891.1 - 5.5e-07 29.2 9.4 0.26 11.0 0.0 5.1 6 0 0 6 6 6 3 TPR repeat TPR_19 PF14559.6 KDO25891.1 - 1.3e-06 28.8 11.3 0.007 16.9 1.6 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 KDO25891.1 - 0.0059 15.6 0.4 0.019 13.9 0.3 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 CAMP_factor PF07373.11 KDO25891.1 - 0.014 15.0 0.2 0.025 14.2 0.2 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) TPR_6 PF13174.6 KDO25891.1 - 0.029 15.0 5.0 16 6.4 0.1 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KDO25891.1 - 0.05 13.6 0.4 5.4 7.0 0.1 3.2 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 NOG1_N PF17835.1 KDO25891.1 - 0.091 12.7 1.0 3.5 7.6 0.1 3.0 2 1 1 3 3 3 0 NOG1 N-terminal helical domain TPR_10 PF13374.6 KDO25891.1 - 0.12 12.3 16.7 3 7.9 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO25891.1 - 0.16 12.2 2.9 3.2 8.1 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ZZ PF00569.17 KDO25893.1 - 3.3e-21 74.8 6.3 5.4e-07 29.3 0.2 3.3 3 0 0 3 3 3 3 Zinc finger, ZZ type PH PF00169.29 KDO25893.1 - 3.3e-10 40.4 0.1 7.5e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO25893.1 - 0.00041 20.6 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO25893.1 - 0.014 15.8 0.2 0.16 12.4 0.2 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Methyltransf_23 PF13489.6 KDO25894.1 - 3.8e-12 46.4 0.0 5.8e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO25894.1 - 7.2e-12 45.9 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO25894.1 - 9.1e-11 42.4 0.0 1.8e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO25894.1 - 1.5e-07 31.9 0.0 3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO25894.1 - 2.9e-07 30.4 0.0 6.8e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KDO25894.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KDO25894.1 - 0.016 14.7 0.0 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.11 KDO25894.1 - 0.064 12.9 0.3 0.35 10.5 0.1 2.3 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SpoU_methylase PF00588.19 KDO25895.1 - 2.7e-29 102.1 0.0 4.4e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KDO25895.1 - 4.6e-12 46.0 0.0 1.9e-11 44.0 0.0 2.1 2 1 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding LVIVD PF08309.11 KDO25896.1 - 4.8e-05 22.6 14.4 0.005 16.1 0.2 4.7 5 0 0 5 5 5 3 LVIVD repeat PQQ_2 PF13360.6 KDO25896.1 - 0.049 13.2 0.0 0.17 11.4 0.0 1.8 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KDO25896.1 - 0.21 10.2 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 MIT PF04212.18 KDO25897.1 - 2.2e-06 27.6 0.5 2.2e-06 27.6 0.5 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Sclerostin PF05463.11 KDO25897.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) Cnn_1N PF07989.11 KDO25897.1 - 0.49 10.6 8.8 20 5.4 0.4 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Rx_N PF18052.1 KDO25897.1 - 0.95 9.8 6.2 1.6 9.0 0.4 3.0 2 1 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 KDO25897.1 - 1.8 9.1 9.8 4 8.0 2.4 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase G-gamma PF00631.22 KDO25897.1 - 3.3 7.8 6.4 14 5.8 0.6 3.0 3 0 0 3 3 3 0 GGL domain Methyltransf_16 PF10294.9 KDO25898.1 - 4.5e-29 101.4 0.0 6.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO25898.1 - 0.00035 20.1 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO25898.1 - 0.0068 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Pkinase PF00069.25 KDO25899.1 - 7e-46 156.7 0.0 7.8e-32 110.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25899.1 - 2.1e-28 99.3 0.0 1.8e-18 66.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO25899.1 - 3.7e-06 26.5 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO25899.1 - 3.9e-05 22.6 0.0 5.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ThiJ_like PF17124.5 KDO25899.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like Kdo PF06293.14 KDO25899.1 - 0.059 12.7 0.7 0.27 10.6 0.2 2.2 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2516 PF10724.9 KDO25899.1 - 0.087 13.1 1.9 0.21 11.9 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) APH PF01636.23 KDO25899.1 - 3.5 7.5 7.3 2.2 8.2 0.1 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family Actin PF00022.19 KDO25900.1 - 1.1e-114 383.2 0.0 9.8e-114 380.1 0.0 1.9 1 1 0 1 1 1 1 Actin Asn_synthase PF00733.21 KDO25901.1 - 7e-21 75.3 0.1 1.6e-14 54.4 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase MMACHC PF16690.5 KDO25901.1 - 6.9e-06 25.9 0.0 0.002 17.8 0.0 2.4 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family MCU PF04678.13 KDO25904.1 - 3.6e-31 108.6 0.5 5.6e-31 108.0 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 KDO25904.1 - 7.3e-08 32.5 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Mito_carr PF00153.27 KDO25905.1 - 1.3e-51 172.4 6.6 7.7e-22 77.0 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KDO25905.1 - 0.00021 20.6 1.0 0.0054 15.9 0.1 2.3 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Methyltransf_16 PF10294.9 KDO25906.1 - 1.2e-32 113.0 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO25906.1 - 0.00043 19.9 0.9 0.0012 18.4 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KDO25906.1 - 0.00099 18.6 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO25906.1 - 0.0027 18.4 0.0 0.0027 18.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO25906.1 - 0.018 14.9 0.0 0.058 13.2 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO25906.1 - 0.05 13.2 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 KDO25906.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KDO25906.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HA PF03457.14 KDO25907.1 - 1.3e-38 131.1 0.2 7.5e-11 42.2 0.0 5.0 5 0 0 5 5 5 4 Helicase associated domain Prominin PF05478.11 KDO25908.1 - 0.0013 16.8 0.8 0.056 11.4 0.4 2.1 2 0 0 2 2 2 1 Prominin Matrilin_ccoil PF10393.9 KDO25908.1 - 0.0093 15.8 6.5 0.17 11.8 0.2 3.8 4 0 0 4 4 4 1 Trimeric coiled-coil oligomerisation domain of matrilin BSMAP PF12280.8 KDO25908.1 - 0.055 13.7 4.0 0.1 12.8 3.3 1.9 1 1 1 2 2 2 0 Brain specific membrane anchored protein Synaptonemal_3 PF15191.6 KDO25908.1 - 0.098 12.4 3.4 0.14 11.9 0.4 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 DUF787 PF05619.11 KDO25908.1 - 0.15 11.2 0.3 0.23 10.6 0.3 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) NPV_P10 PF05531.12 KDO25908.1 - 0.24 11.9 7.2 5.2 7.6 0.1 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KDO25908.1 - 0.25 11.4 25.0 3 7.9 3.0 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALIX_LYPXL_bnd PF13949.6 KDO25908.1 - 0.49 9.6 20.3 1.7 7.8 19.1 2.3 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DASH_Dam1 PF08653.10 KDO25908.1 - 0.94 9.3 2.5 10 6.0 0.4 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF1664 PF07889.12 KDO25908.1 - 1.1 9.4 9.0 0.37 10.8 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KDO25908.1 - 2.2 6.1 16.0 0.7 7.7 6.0 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family BRE1 PF08647.11 KDO25908.1 - 2.9 8.0 19.5 6.4 6.9 1.8 3.1 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 KDO25908.1 - 4.4 7.3 15.1 0.19 11.8 1.3 3.2 2 1 0 3 3 3 0 Laminin Domain II Rnk_N PF14760.6 KDO25908.1 - 5.2 7.6 10.4 5.8 7.5 0.0 4.6 4 0 0 4 4 4 0 Rnk N-terminus CDP-OH_P_transf PF01066.21 KDO25909.1 - 2.3e-14 53.9 0.2 2.3e-14 53.9 0.2 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase XAP5 PF04921.14 KDO25910.1 - 6.1e-68 229.3 10.0 5.7e-67 226.2 10.2 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Peptidase_C37 PF05416.12 KDO25910.1 - 0.17 10.4 4.9 0.15 10.5 0.8 2.0 1 1 1 2 2 2 0 Southampton virus-type processing peptidase DUF4604 PF15377.6 KDO25910.1 - 0.78 10.2 11.4 0.058 13.8 6.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) WD40 PF00400.32 KDO25911.1 - 2.9e-08 34.2 1.4 5.5e-05 23.9 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO25911.1 - 0.0063 16.8 0.0 4.3 7.7 0.0 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain C1_2 PF03107.16 KDO25911.1 - 0.16 12.3 0.5 0.53 10.6 0.5 1.8 1 0 0 1 1 1 0 C1 domain Kelch_1 PF01344.25 KDO25911.1 - 0.44 10.2 2.5 7.1 6.3 0.1 3.3 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.32 KDO25912.1 - 2.8e-08 34.3 30.9 2.4e-06 28.1 0.2 8.8 9 2 1 10 10 10 2 WD domain, G-beta repeat Nup160 PF11715.8 KDO25912.1 - 0.00033 19.5 3.8 0.029 13.0 0.0 4.3 3 2 2 5 5 5 1 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 KDO25912.1 - 0.0033 17.8 0.2 0.022 15.2 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 KDO25912.1 - 0.0037 17.5 1.4 4.5 7.7 0.0 5.5 5 2 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 KDO25912.1 - 0.0085 15.9 0.1 0.056 13.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KDO25912.1 - 0.026 14.0 0.0 0.077 12.5 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KDO25912.1 - 0.029 13.9 0.6 0.17 11.5 0.1 2.5 3 0 0 3 3 3 0 EF hand LAMTOR PF15454.6 KDO25913.1 - 0.088 13.4 0.1 0.33 11.6 0.1 2.0 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Myb_DNA-bind_4 PF13837.6 KDO25913.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain F-actin_cap_A PF01267.17 KDO25914.1 - 4.2e-75 252.6 0.1 4.8e-75 252.4 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Porphobil_deam PF01379.20 KDO25914.1 - 0.095 12.2 0.0 0.96 8.9 0.0 2.1 1 1 1 2 2 2 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain RNA_pol_L_2 PF13656.6 KDO25915.1 - 2.5e-30 104.0 0.0 3.1e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KDO25915.1 - 1.9e-09 36.8 0.0 2.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TPR_12 PF13424.6 KDO25916.1 - 1.5e-16 60.5 7.4 1.3e-07 31.8 0.4 4.3 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25916.1 - 3.9e-14 52.0 5.3 8.2e-06 25.5 1.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25916.1 - 2.8e-13 49.1 2.3 0.0012 18.5 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25916.1 - 4e-13 48.4 4.4 7.5e-05 22.5 0.4 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25916.1 - 7e-07 28.8 3.4 0.003 17.5 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25916.1 - 3.2e-06 26.9 0.9 0.2 12.0 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO25916.1 - 0.00046 20.8 2.6 0.11 13.2 0.7 3.1 3 2 0 3 3 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO25916.1 - 0.0019 18.7 6.8 0.9 10.4 0.2 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25916.1 - 0.006 17.1 6.2 0.087 13.3 0.6 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25916.1 - 0.015 16.1 6.4 5.4 8.1 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat CorA PF01544.18 KDO25916.1 - 0.016 14.6 1.2 0.02 14.2 0.4 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TPR_MalT PF17874.1 KDO25916.1 - 0.017 14.5 7.3 0.019 14.4 2.8 2.3 1 1 1 2 2 2 0 MalT-like TPR region TPR_15 PF13429.6 KDO25916.1 - 0.052 12.8 1.1 0.38 9.9 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO25916.1 - 0.33 11.4 1.8 5.2 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO25916.1 - 0.43 10.3 4.9 1.3 8.8 0.0 3.7 4 1 1 5 5 5 0 TPR repeat DUF4368 PF14287.6 KDO25917.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) UPF0242 PF06785.11 KDO25918.1 - 0.091 12.9 2.4 0.13 12.3 2.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHHC PF01529.20 KDO25919.1 - 1.2e-25 90.1 1.2 1.2e-25 90.1 1.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KDO25919.1 - 9.3e-24 83.5 8.9 1.8e-06 28.4 0.1 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO25919.1 - 1e-21 77.3 2.4 2.1e-10 41.1 0.3 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO25919.1 - 3e-18 65.6 12.9 8.2e-08 32.4 0.3 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25919.1 - 5.1e-17 60.2 8.8 3.2e-05 24.0 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO25919.1 - 1.4e-12 47.4 10.0 0.00019 21.7 0.4 5.7 6 0 0 6 6 6 3 Ankyrin repeat Dus PF01207.17 KDO25921.1 - 8.3e-58 195.9 0.0 9.2e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Glyco_hydro_18 PF00704.28 KDO25921.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KDO25921.1 - 0.026 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DHO_dh PF01180.21 KDO25921.1 - 0.13 11.5 0.0 3.5 6.8 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Mito_carr PF00153.27 KDO25922.1 - 1.2e-56 188.6 3.8 7.1e-20 70.7 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO25922.1 - 0.0026 17.0 4.1 0.13 11.4 0.2 2.6 2 1 0 3 3 3 2 Gammaproteobacterial serine protease DUF4787 PF16029.5 KDO25923.1 - 8.9e-17 60.9 3.2 1e-16 60.7 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) cNMP_binding PF00027.29 KDO25924.1 - 1e-36 124.9 11.6 5.7e-06 26.3 0.1 9.4 7 3 0 7 7 7 7 Cyclic nucleotide-binding domain KduI PF04962.12 KDO25924.1 - 0.25 10.6 2.5 2.5 7.3 0.0 3.1 4 0 0 4 4 4 0 KduI/IolB family FYVE PF01363.21 KDO25925.1 - 2.8e-16 59.4 7.4 2.8e-16 59.4 7.4 2.7 2 1 1 3 3 2 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO25925.1 - 7.8e-14 51.7 27.1 1.4e-13 51.0 7.6 3.0 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KDO25925.1 - 1.4e-09 37.7 7.5 1.4e-09 37.7 7.5 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO25925.1 - 4.7e-09 35.8 3.6 4.7e-09 35.8 3.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO25925.1 - 2.9e-07 30.4 1.5 2.9e-07 30.4 1.5 3.4 3 1 1 4 4 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO25925.1 - 4.1e-07 29.9 5.3 4.1e-07 29.9 5.3 3.2 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO25925.1 - 9.6e-07 28.6 5.3 9.6e-07 28.6 5.3 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO25925.1 - 1.5e-06 28.4 11.2 1.5e-06 28.4 11.2 3.4 3 1 0 3 3 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KDO25925.1 - 5.6e-06 26.1 21.0 6.2e-05 22.8 6.4 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KDO25925.1 - 2e-05 24.3 5.2 2e-05 24.3 5.2 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO25925.1 - 0.0012 18.9 5.5 0.0012 18.9 5.5 2.7 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.16 KDO25925.1 - 0.026 14.7 5.7 0.026 14.7 5.7 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.14 KDO25925.1 - 0.088 12.7 1.5 0.29 11.0 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 KDO25925.1 - 1.8 8.5 26.1 0.26 11.2 5.6 5.5 4 2 1 5 5 5 0 Prokaryotic RING finger family 1 UPF0547 PF10571.9 KDO25925.1 - 2.4 8.3 0.1 2.4 8.3 0.1 4.5 6 1 0 6 6 5 0 Uncharacterised protein family UPF0547 Zn_ribbon_17 PF17120.5 KDO25925.1 - 3.6 7.3 30.8 0.061 13.0 10.8 3.5 2 1 1 3 3 2 0 Zinc-ribbon, C4HC2 type zf_C2HC_14 PF18574.1 KDO25925.1 - 4.1 7.3 12.5 0.35 10.7 4.3 3.0 2 0 0 2 2 2 0 C2HC Zing finger domain Dus PF01207.17 KDO25926.1 - 6.3e-63 212.7 0.0 7.3e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KDO25926.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein HA PF03457.14 KDO25927.1 - 2.4e-05 24.6 0.0 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain CHCH PF06747.13 KDO25929.1 - 6.4e-05 23.0 6.1 8.7e-05 22.5 6.1 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KDO25929.1 - 0.0024 17.8 6.7 0.14 12.2 0.7 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KDO25929.1 - 0.03 14.6 3.5 0.04 14.2 3.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 KDO25929.1 - 0.1 12.3 3.9 0.19 11.5 2.2 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 KDO25929.1 - 0.37 11.1 6.3 0.85 9.9 6.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) AA_kinase PF00696.28 KDO25930.1 - 1.8e-37 129.3 1.4 1.8e-37 129.3 1.4 1.9 2 0 0 2 2 2 1 Amino acid kinase family Homoserine_dh PF00742.19 KDO25930.1 - 1.6e-14 54.2 0.0 6.3e-14 52.3 0.0 2.1 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT PF01842.25 KDO25930.1 - 1.4e-13 50.3 0.5 2.2e-05 24.1 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KDO25930.1 - 1.7e-12 46.9 1.5 1.9e-05 24.4 0.0 3.3 3 0 0 3 3 3 2 ACT domain NAD_binding_3 PF03447.16 KDO25930.1 - 1.5e-05 25.6 6.5 1.5e-05 25.6 0.2 3.6 4 0 0 4 4 4 1 Homoserine dehydrogenase, NAD binding domain ACT_6 PF13740.6 KDO25930.1 - 0.15 12.1 1.7 34 4.5 0.0 3.7 3 0 0 3 3 3 0 ACT domain ubiquitin PF00240.23 KDO25931.1 - 1.6e-09 37.4 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KDO25931.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO25931.1 - 0.049 14.2 0.0 0.083 13.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AZUL PF16558.5 KDO25932.1 - 2.2e-13 50.2 2.6 3.1e-13 49.7 0.2 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Sugar_tr PF00083.24 KDO25933.1 - 2.5e-126 422.2 19.7 3.3e-126 421.8 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO25933.1 - 6.7e-24 84.5 32.3 6.7e-24 84.5 32.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO25933.1 - 0.00015 20.4 0.9 0.00015 20.4 0.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_1 PF00515.28 KDO25935.1 - 0.003 17.3 0.0 0.61 10.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25935.1 - 0.005 17.0 0.0 4.4 7.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO25935.1 - 0.013 15.5 0.4 1.3 9.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25935.1 - 0.049 14.5 0.4 5 8.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25935.1 - 0.071 13.6 2.9 0.56 10.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 KDO25936.1 - 0.018 13.4 28.9 0.02 13.2 28.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KDO25936.1 - 0.089 12.1 40.2 0.092 12.1 40.2 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 KDO25936.1 - 0.34 9.3 31.3 0.43 9.0 31.3 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 KDO25936.1 - 0.96 7.6 38.0 1 7.5 38.0 1.2 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 KDO25936.1 - 1.1 8.3 8.6 1.2 8.2 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC27 PF09507.10 KDO25936.1 - 3.2 7.0 29.7 3.5 6.9 29.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 KDO25936.1 - 3.5 7.0 42.4 3.9 6.8 42.4 1.2 1 0 0 1 1 1 0 SDA1 CCSAP PF15748.5 KDO25936.1 - 4.6 7.3 12.6 5.8 7.0 12.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 KDO25936.1 - 6.6 5.4 13.7 6.4 5.4 13.7 1.1 1 0 0 1 1 1 0 Presenilin Ribonucleas_3_3 PF14622.6 KDO25937.1 - 4.2e-21 75.4 0.3 9.8e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KDO25937.1 - 1.1e-19 70.9 0.1 2.9e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain Dus PF01207.17 KDO25938.1 - 6.5e-35 120.7 0.0 1e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KDO25938.1 - 3.4e-07 29.9 10.9 0.00057 19.6 0.1 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 KDO25938.1 - 1.9e-06 27.6 5.8 0.0053 16.6 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO25938.1 - 0.051 13.6 11.7 1.2 9.3 2.8 2.6 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 KDO25938.1 - 0.054 14.0 4.4 5.2 7.7 0.6 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KDO25938.1 - 6.2 7.6 5.4 32 5.3 0.2 2.4 1 1 1 2 2 2 0 Torus domain Plus-3 PF03126.18 KDO25939.1 - 1.6e-16 60.8 1.3 3.7e-16 59.6 0.2 2.2 2 0 0 2 2 2 1 Plus-3 domain AIRC PF00731.20 KDO25940.1 - 5.1e-18 65.1 1.6 5.1e-18 65.1 1.6 1.8 2 0 0 2 2 2 1 AIR carboxylase Adeno_E4_34 PF04528.13 KDO25940.1 - 0.071 13.0 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Glycos_transf_1 PF00534.20 KDO25942.1 - 1.6e-18 66.8 0.0 3.1e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO25942.1 - 3.3e-16 59.9 0.0 6.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KDO25942.1 - 5.9e-11 42.7 0.3 5.9e-11 42.7 0.3 2.1 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KDO25942.1 - 7.9e-08 32.9 0.3 7.9e-08 32.9 0.3 2.9 2 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KDO25942.1 - 0.052 13.9 0.0 0.052 13.9 0.0 1.9 2 1 0 2 2 2 0 Glycosyl transferases group 1 BRCT_2 PF16589.5 KDO25944.1 - 6e-20 71.4 0.0 2.6e-10 40.5 0.0 4.4 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KDO25944.1 - 7.3e-13 48.7 0.0 5.4e-06 26.7 0.0 4.0 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-RanBP PF00641.18 KDO25944.1 - 1.7e-05 24.0 2.8 4.2e-05 22.8 2.8 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RTT107_BRCT_5 PF16770.5 KDO25944.1 - 7.6e-05 22.5 0.0 7.6e-05 22.5 0.0 3.5 4 1 1 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KDO25944.1 - 0.00042 20.2 2.4 7.6 6.6 0.1 4.2 3 2 0 3 3 3 2 twin BRCT domain LIG3_BRCT PF16759.5 KDO25944.1 - 0.11 12.9 11.9 3.9 7.8 0.0 4.9 6 0 0 6 6 6 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KDO25944.1 - 0.34 11.0 4.3 4.7 7.3 0.1 4.1 3 3 2 5 5 5 0 BRCA1 C Terminus (BRCT) domain zinc_ribbon_2 PF13240.6 KDO25944.1 - 0.82 9.5 5.4 1.9 8.3 5.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KDO25944.1 - 5.7 7.0 8.7 0.11 12.5 1.0 2.1 2 0 0 2 2 2 0 Double zinc ribbon PRP38_assoc PF12871.7 KDO25945.1 - 1 10.0 17.1 1.3 9.7 17.1 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MIF4G PF02854.19 KDO25946.1 - 2.5e-22 79.6 0.0 3.4e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 KDO25946.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region ATP-grasp_4 PF13535.6 KDO25947.1 - 4.4e-13 49.1 0.0 1.8e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KDO25947.1 - 8.9e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KDO25947.1 - 4.6e-05 23.5 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 KDO25947.1 - 0.00022 21.0 0.0 0.00085 19.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KDO25947.1 - 0.00065 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_N PF18130.1 KDO25947.1 - 0.0049 17.4 0.1 0.05 14.2 0.0 2.7 3 1 0 3 3 3 1 ATP-grasp N-terminal domain TTL PF03133.15 KDO25947.1 - 0.041 13.0 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Bestrophin PF01062.21 KDO25948.1 - 1.8e-26 93.2 3.0 2.5e-26 92.7 3.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GoLoco PF02188.17 KDO25948.1 - 0.074 12.6 0.3 0.17 11.5 0.3 1.6 1 0 0 1 1 1 0 GoLoco motif MotB_plug PF13677.6 KDO25948.1 - 0.096 12.3 2.4 0.22 11.2 2.4 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Glycos_transf_3 PF00591.21 KDO25949.1 - 5.4e-92 308.0 0.1 8.1e-92 307.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KDO25949.1 - 6.6e-16 57.9 1.9 9.9e-16 57.3 1.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain TPH PF13868.6 KDO25950.1 - 1.1e-34 119.5 111.7 1.1e-34 119.5 111.7 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Myb_DNA-binding PF00249.31 KDO25951.1 - 0.0012 19.0 0.1 0.0028 17.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain COQ7 PF03232.13 KDO25952.1 - 1e-11 44.9 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 GST_C PF00043.25 KDO25952.1 - 0.085 13.1 0.1 0.35 11.1 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PH PF00169.29 KDO25953.1 - 1.2e-09 38.6 0.1 3.1e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO25953.1 - 2.1e-05 24.7 0.2 0.00024 21.3 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 KDO25953.1 - 5e-05 23.5 3.1 5e-05 23.5 3.1 2.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Cellulose_synt PF03552.14 KDO25953.1 - 0.00017 20.3 0.8 0.018 13.6 0.0 2.6 3 0 0 3 3 3 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 KDO25953.1 - 0.00067 19.6 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KDO25953.1 - 0.0053 16.6 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Mcp5_PH PF12814.7 KDO25953.1 - 0.055 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 KDO25953.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Sec34 PF04136.15 KDO25954.1 - 3.7e-19 69.1 0.3 2.4e-11 43.7 0.1 2.7 2 0 0 2 2 2 2 Sec34-like family DUF2508 PF10704.9 KDO25954.1 - 1.1 9.5 4.0 1.5 9.0 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) PIF1 PF05970.14 KDO25955.1 - 6.6e-46 157.1 0.6 3.4e-39 135.0 0.1 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KDO25955.1 - 7.6e-24 84.5 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO25955.1 - 1.1e-08 35.5 0.0 3.3e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO25955.1 - 5.7e-05 23.6 0.1 0.00012 22.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO25955.1 - 5.9e-05 23.4 0.3 0.00028 21.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KDO25955.1 - 0.00011 21.7 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 KDO25955.1 - 0.00022 21.3 0.0 0.00083 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KDO25955.1 - 0.00084 18.7 0.0 0.041 13.1 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KDO25955.1 - 0.0014 18.4 0.1 0.25 11.1 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KDO25955.1 - 0.0035 16.9 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KDO25955.1 - 0.0036 17.2 1.3 0.0058 16.6 0.0 2.0 3 0 0 3 3 2 1 NACHT domain IstB_IS21 PF01695.17 KDO25955.1 - 0.0052 16.5 0.0 0.082 12.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein UvrD_C_2 PF13538.6 KDO25955.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 KDO25955.1 - 0.07 13.6 0.0 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 KDO25955.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KDO25955.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 KDO25955.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Herpes_Helicase PF02689.14 KDO25955.1 - 0.1 10.5 0.2 1.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Helicase DUF815 PF05673.13 KDO25955.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Torsin PF06309.11 KDO25955.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.15 KDO25955.1 - 0.14 12.1 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KDO25955.1 - 0.15 12.1 0.0 0.44 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain SF-assemblin PF06705.11 KDO25956.1 - 6e-05 22.5 23.6 7.8e-05 22.1 23.6 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin SopA PF13981.6 KDO25956.1 - 0.021 15.2 1.6 0.48 10.8 0.2 2.3 2 0 0 2 2 2 0 SopA-like central domain SCFA_trans PF02667.14 KDO25956.1 - 0.12 11.3 0.3 0.18 10.8 0.3 1.2 1 0 0 1 1 1 0 Short chain fatty acid transporter RGS PF00615.19 KDO25956.1 - 0.96 9.7 9.8 24 5.2 4.4 3.4 1 1 1 2 2 2 0 Regulator of G protein signaling domain Ribosomal_L37e PF01907.19 KDO25957.1 - 3.4e-28 97.6 12.4 5.7e-28 96.8 12.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DUF2688 PF10892.8 KDO25957.1 - 0.018 14.5 4.0 0.14 11.7 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) DZR PF12773.7 KDO25957.1 - 0.024 14.7 1.3 0.036 14.1 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF1258 PF06869.12 KDO25957.1 - 0.072 12.6 1.2 0.092 12.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) HypA PF01155.19 KDO25957.1 - 0.11 12.6 1.2 0.15 12.1 1.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ank_2 PF12796.7 KDO25958.1 - 1.7e-12 47.8 0.3 8.2e-05 23.1 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO25958.1 - 3.6e-11 43.1 1.0 3.9e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO25958.1 - 1.6e-07 31.7 1.9 0.0036 17.8 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO25958.1 - 1.8e-07 30.9 0.5 0.0015 18.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KDO25958.1 - 6e-07 29.6 6.7 0.00094 19.5 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 KDO25958.1 - 0.00067 20.5 0.0 0.0013 19.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KDO25958.1 - 0.01 16.1 1.1 0.051 13.8 0.2 2.3 2 1 1 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.6 KDO25960.1 - 1.3e-51 175.8 41.5 1.7e-51 175.4 41.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO25960.1 - 2.2e-08 33.2 39.5 3.8e-08 32.4 39.5 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO25961.1 - 1.7e-50 172.1 42.8 3.1e-50 171.2 42.8 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO25961.1 - 4.3e-06 25.6 39.9 6.9e-06 24.9 39.9 1.3 1 0 0 1 1 1 1 Amino acid permease SKIP_SNW PF02731.15 KDO25963.1 - 2.6e-70 235.2 2.0 2.6e-70 235.2 2.0 1.9 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 KDO25963.1 - 3.7 7.2 35.4 0.064 13.0 17.8 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AIP3 PF03915.13 KDO25964.1 - 0.0028 16.8 9.3 0.0028 16.8 9.3 2.2 2 0 0 2 2 2 1 Actin interacting protein 3 E2F_CC-MB PF16421.5 KDO25964.1 - 0.043 14.2 0.5 0.043 14.2 0.5 3.3 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain NblA PF04485.12 KDO25964.1 - 0.18 12.2 2.1 0.76 10.2 2.1 2.1 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Fib_alpha PF08702.10 KDO25964.1 - 0.62 10.2 22.6 0.66 10.2 2.8 3.7 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4238 PF14022.6 KDO25964.1 - 3.4 7.1 7.2 0.29 10.6 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4238) ACCA PF03255.14 KDO25964.1 - 4 7.3 18.6 0.21 11.4 2.1 3.6 2 1 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YscO PF07321.12 KDO25964.1 - 4.1 7.3 40.7 0.26 11.2 11.3 3.1 3 0 0 3 3 3 0 Type III secretion protein YscO LXG PF04740.12 KDO25964.1 - 6 6.5 19.5 0.024 14.4 4.9 3.0 2 1 1 3 3 3 0 LXG domain of WXG superfamily TPR_MLP1_2 PF07926.12 KDO25964.1 - 8.3 6.5 35.4 0.066 13.3 12.9 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-X PF09415.10 KDO25965.1 - 3.8e-10 39.9 0.7 5.1e-09 36.3 0.1 2.0 1 1 1 2 2 2 1 CENP-S associating Centromere protein X FAD_binding_3 PF01494.19 KDO25968.1 - 1.2e-70 238.6 0.0 1.5e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KDO25968.1 - 0.011 14.7 0.3 0.45 9.3 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase AAA_12 PF13087.6 KDO25970.1 - 3.7e-12 46.3 0.0 4.3e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KDO25971.1 - 2.4e-15 57.0 0.0 4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KDO25971.1 - 0.00013 22.0 0.0 0.00057 20.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO25971.1 - 0.015 15.6 0.1 0.073 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Vps8 PF12816.7 KDO25972.1 - 1.3e-37 129.2 0.7 8.8e-36 123.3 0.3 2.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KDO25972.1 - 2.9e-10 40.2 1.1 5.9e-06 26.2 0.0 3.8 3 0 0 3 3 3 3 Region in Clathrin and VPS WWE PF02825.20 KDO25972.1 - 0.0006 20.3 0.7 0.64 10.6 0.0 3.8 3 1 1 4 4 4 2 WWE domain WD40 PF00400.32 KDO25972.1 - 0.0025 18.6 2.6 0.004 18.0 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat CcmD PF04995.14 KDO25973.1 - 1.7 8.8 8.1 0.23 11.6 0.6 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Ricin_B_lectin PF00652.22 KDO25975.1 - 1.9e-17 63.7 19.7 2.1e-09 37.7 2.6 2.6 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain ATP-synt_D PF01813.17 KDO25976.1 - 2.7e-47 161.1 0.1 3.6e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF1451 PF07295.11 KDO25976.1 - 0.12 12.4 0.2 0.26 11.3 0.2 1.5 1 1 0 1 1 1 0 Zinc-ribbon containing domain ATP-synt_D PF01813.17 KDO25977.1 - 1.6e-06 28.1 1.6 1.7e-06 28.0 1.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit D HALZ PF02183.18 KDO25977.1 - 0.053 13.8 0.0 0.066 13.4 0.0 1.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.25 KDO25978.1 - 2.8e-75 253.1 0.0 3.2e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25978.1 - 1.3e-34 119.6 0.0 1.8e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25978.1 - 1.3e-05 24.7 0.0 0.00039 19.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO25978.1 - 0.00028 20.6 0.2 0.0004 20.0 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KDO25978.1 - 0.001 18.4 0.1 0.002 17.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO25978.1 - 0.0023 17.9 0.4 0.11 12.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KDO25978.1 - 0.003 17.2 0.1 0.41 10.2 0.0 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO25978.1 - 0.011 14.7 0.3 0.017 14.0 0.3 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Arf PF00025.21 KDO25979.1 - 1.1e-44 152.0 0.1 1.2e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO25979.1 - 1.2e-12 48.1 0.0 1.8e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO25979.1 - 4.3e-11 42.7 0.0 5.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KDO25979.1 - 2.9e-10 39.8 0.1 1.4e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO25979.1 - 2.1e-09 37.5 0.0 3.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO25979.1 - 9.3e-08 31.7 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KDO25979.1 - 1.3e-06 28.0 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KDO25979.1 - 5.2e-06 26.1 0.0 0.00011 21.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KDO25979.1 - 0.00013 21.6 0.0 0.038 13.6 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KDO25979.1 - 0.0077 15.8 0.8 0.11 12.0 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO25979.1 - 0.017 15.2 0.2 4.2 7.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KDO25979.1 - 0.041 13.8 0.1 8.5 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KDO25979.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 NTPase Phosducin PF02114.16 KDO25980.1 - 1.4e-17 63.5 0.2 2.6e-16 59.4 0.2 2.0 1 1 0 1 1 1 1 Phosducin Serinc PF03348.15 KDO25981.1 - 3.7e-60 204.1 17.7 3.3e-40 138.3 9.2 2.0 1 1 0 2 2 2 2 Serine incorporator (Serinc) zf-CCCH PF00642.24 KDO25982.1 - 5.8e-13 48.4 11.3 4.8e-07 29.5 2.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO25982.1 - 2e-12 46.6 11.7 4.6e-06 26.3 2.0 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO25982.1 - 7.8e-12 44.8 16.5 1.1e-05 25.4 4.3 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KDO25982.1 - 4e-05 24.3 8.9 0.0027 18.4 0.9 2.5 1 1 1 2 2 2 2 Torus domain zf-C2H2_jaz PF12171.8 KDO25982.1 - 0.00035 20.8 5.5 0.00038 20.7 0.2 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-CCCH_3 PF15663.5 KDO25982.1 - 0.00051 20.2 5.9 0.0014 18.8 5.9 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-C2H2 PF00096.26 KDO25982.1 - 0.0013 19.0 1.3 0.045 14.2 0.2 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-CCCH_2 PF14608.6 KDO25982.1 - 0.0049 17.3 12.2 0.25 11.9 2.5 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-met PF12874.7 KDO25982.1 - 0.0073 16.7 0.7 0.0073 16.7 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KDO25982.1 - 0.01 16.1 1.6 0.014 15.7 0.7 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KDO25982.1 - 0.018 15.0 0.7 0.086 12.9 0.7 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KDO25982.1 - 0.064 14.1 5.2 0.098 13.5 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Rogdi_lz PF10259.9 KDO25983.1 - 6.5e-13 48.7 0.2 7.8e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF3670 PF12419.8 KDO25983.1 - 0.0087 15.9 0.3 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 SNF2 Helicase protein IQ PF00612.27 KDO25984.1 - 3.1e-05 23.4 9.0 0.0089 15.7 5.6 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif DZR PF12773.7 KDO25984.1 - 0.0053 16.7 3.7 0.013 15.5 3.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO25984.1 - 0.016 14.9 3.2 0.028 14.1 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF5470 PF17564.2 KDO25984.1 - 0.022 15.0 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5470) zf-ribbon_3 PF13248.6 KDO25984.1 - 7.7 6.1 6.9 25 4.5 6.9 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Mito_carr PF00153.27 KDO25985.1 - 1.3e-67 223.8 6.9 5.2e-25 87.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5060 PF16586.5 KDO25985.1 - 0.018 15.4 0.0 0.055 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) Mito_carr PF00153.27 KDO25986.1 - 5.9e-69 228.1 5.1 1.5e-25 88.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 KDO25987.1 - 4.8e-134 447.7 0.0 8.3e-134 446.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.22 KDO25988.1 - 5.5e-35 119.0 0.1 7.5e-17 60.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KDO25988.1 - 7.7e-32 108.6 40.4 1.9e-06 27.6 1.4 6.7 6 0 0 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO25988.1 - 2.2e-25 87.9 68.3 2.2e-05 24.3 3.8 7.2 6 1 0 6 6 6 6 Zinc finger domain zf-CCCH_4 PF18044.1 KDO25988.1 - 1.6e-22 78.8 51.8 1.3e-05 24.9 1.7 6.4 6 0 0 6 6 6 6 CCCH-type zinc finger Torus PF16131.5 KDO25988.1 - 5.2e-18 65.7 30.6 0.00081 20.1 0.1 6.7 6 1 1 7 7 7 6 Torus domain zf-CCCH_3 PF15663.5 KDO25988.1 - 2.6e-12 46.9 24.1 0.17 12.1 0.3 6.2 3 2 1 5 5 5 5 Zinc-finger containing family RRM_7 PF16367.5 KDO25988.1 - 1.5e-06 28.2 0.1 0.00094 19.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif zf-CCCH_2 PF14608.6 KDO25988.1 - 0.04 14.4 51.7 1.3 9.6 1.3 6.8 7 0 0 7 7 7 0 RNA-binding, Nab2-type zinc finger RNA_polI_A34 PF08208.11 KDO25988.1 - 0.2 11.7 12.1 0.38 10.8 12.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Mucin PF01456.17 KDO25989.1 - 0.077 13.0 6.4 0.099 12.6 6.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Sld5 PF05916.11 KDO25990.1 - 2.5e-21 76.2 0.3 3.9e-21 75.6 0.3 1.3 1 0 0 1 1 1 1 GINS complex protein Glyoxalase PF00903.25 KDO25991.1 - 3.5e-10 40.2 0.0 4e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO25991.1 - 0.00041 21.1 0.0 0.00051 20.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain BAR PF03114.18 KDO25992.1 - 0.0039 16.9 3.8 0.0064 16.2 3.3 1.6 1 1 0 1 1 1 1 BAR domain PIN_8 PF18476.1 KDO25992.1 - 0.21 11.4 3.6 0.34 10.7 2.8 1.6 1 1 0 1 1 1 0 PIN like domain Pkinase PF00069.25 KDO25993.1 - 4.2e-72 242.7 0.0 6.5e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO25993.1 - 1.3e-43 149.1 0.0 2e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO25993.1 - 2.5e-07 30.3 0.0 4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO25993.1 - 0.00018 20.9 1.4 0.00032 20.1 1.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO25993.1 - 0.005 16.5 0.7 0.01 15.5 0.7 1.5 1 0 0 1 1 1 1 RIO1 family DUF3439 PF11921.8 KDO25993.1 - 0.016 15.2 11.6 0.016 15.2 11.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) APH PF01636.23 KDO25993.1 - 0.034 14.1 0.3 0.24 11.3 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family LON_substr_bdg PF02190.16 KDO25994.1 - 1.2e-13 51.4 0.0 3.7e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 KDO25994.1 - 8.8e-10 38.7 0.5 1.6e-09 37.9 0.5 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HSP70 PF00012.20 KDO25995.1 - 4.6e-40 137.4 0.3 7.6e-40 136.7 0.2 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO25995.1 - 5.1e-05 22.3 0.2 0.0001 21.2 0.2 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KDO25995.1 - 0.028 14.4 0.0 0.08 13.0 0.0 1.8 1 1 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HEPPP_synt_1 PF07307.11 KDO25995.1 - 0.05 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TPR_2 PF07719.17 KDO25996.1 - 3.2e-08 33.1 4.2 0.043 13.9 2.5 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO25996.1 - 1.7e-07 31.4 9.8 0.016 15.5 3.5 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO25996.1 - 1.9e-07 30.6 2.2 0.049 13.5 1.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO25996.1 - 7.8e-06 25.6 4.6 0.047 13.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO25996.1 - 0.00029 21.3 11.6 0.54 10.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO25996.1 - 0.0003 20.8 5.0 1.2 9.5 1.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO25996.1 - 0.0018 18.0 4.2 0.15 12.0 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO25996.1 - 0.0063 17.2 16.4 1.3 10.0 0.0 5.9 4 2 3 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO25996.1 - 0.0066 17.0 2.5 11 6.9 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 KDO25996.1 - 0.013 15.2 0.0 1.6 8.4 0.2 2.7 2 2 0 2 2 2 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 KDO25996.1 - 0.015 15.5 7.1 2.4 8.4 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KDO25996.1 - 0.047 13.4 5.8 0.82 9.4 1.3 4.1 2 1 3 5 5 5 0 TPR repeat TPR_16 PF13432.6 KDO25996.1 - 0.08 13.6 22.4 0.29 11.8 0.1 5.1 4 2 2 6 6 5 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KDO25997.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KDO25997.1 - 3e-05 24.7 0.0 6.9e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO25997.1 - 0.0035 17.7 0.0 0.0058 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO25997.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO25997.1 - 0.033 14.1 0.0 0.095 12.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.7 KDO25997.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO25997.1 - 0.088 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4878 PF12870.7 KDO25999.1 - 0.22 11.9 0.0 0.36 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) CoatB PF10389.9 KDO26000.1 - 2.9 7.8 6.5 2 8.3 4.2 1.9 2 0 0 2 2 2 0 Bacteriophage coat protein B Mo25 PF08569.11 KDO26001.1 - 7.2e-121 403.5 10.8 8.2e-121 403.4 10.8 1.0 1 0 0 1 1 1 1 Mo25-like SOUL PF04832.12 KDO26001.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein Pkinase PF00069.25 KDO26002.1 - 1.3e-60 205.0 0.0 1.8e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26002.1 - 4.4e-31 108.1 0.0 6.1e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO26002.1 - 5.2e-08 32.5 0.0 7.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KDO26002.1 - 3e-05 23.1 0.0 6.4e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO26002.1 - 0.0039 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KDO26002.1 - 0.011 15.7 0.3 0.023 14.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO26002.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO26002.1 - 0.021 14.5 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KDO26002.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DSPc PF00782.20 KDO26003.1 - 1.5e-23 83.1 0.0 2.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ASCH PF04266.14 KDO26003.1 - 1.7e-05 25.3 0.0 3.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 ASCH domain Y_phosphatase PF00102.27 KDO26003.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KDO26003.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Pkinase PF00069.25 KDO26004.1 - 2.2e-36 125.6 0.0 3e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26004.1 - 4.4e-18 65.5 0.0 1.4e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO26004.1 - 3.2e-05 23.4 0.0 4.4e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KDO26004.1 - 0.00069 19.6 0.9 0.0077 16.2 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO26004.1 - 0.0046 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRK PF00485.18 KDO26005.1 - 0.00014 21.7 0.0 0.0015 18.3 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 KDO26005.1 - 0.00086 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KDO26005.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pkinase PF00069.25 KDO26006.1 - 1.1e-07 31.6 0.0 1.2e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26006.1 - 0.0043 16.4 0.0 0.0046 16.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Cdc6_C PF09079.11 KDO26006.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain EF-hand_7 PF13499.6 KDO26007.1 - 5.7e-05 23.5 5.8 0.0043 17.5 5.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO26007.1 - 0.0016 18.2 7.4 0.01 15.7 2.5 3.0 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KDO26007.1 - 0.01 15.3 7.8 0.023 14.2 3.6 3.1 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 KDO26007.1 - 0.051 13.4 6.1 0.12 12.3 2.3 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KDO26007.1 - 1.1 8.9 3.5 2.4 7.8 2.3 2.2 2 0 0 2 2 2 0 EF hand Condensin2nSMC PF12422.8 KDO26009.1 - 8.1e-08 32.6 0.1 3.3e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KDO26009.1 - 0.0004 20.4 4.3 2.9 8.4 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KDO26009.1 - 0.0085 16.5 0.2 1 9.8 0.2 3.2 1 1 1 2 2 2 2 HEAT repeats Pkinase PF00069.25 KDO26010.1 - 6.1e-45 153.6 0.0 8.6e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26010.1 - 4.5e-44 150.7 0.0 6.1e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO26010.1 - 0.0044 15.8 0.0 0.0068 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RskA PF10099.9 KDO26010.1 - 0.038 14.3 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PepSY_TM PF03929.16 KDO26010.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Haspin_kinase PF12330.8 KDO26010.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO26010.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family VWA PF00092.28 KDO26012.1 - 6.9e-08 32.9 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KDO26012.1 - 1.8e-07 31.8 0.0 6.8e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KDO26012.1 - 6e-05 21.4 0.0 8.5e-05 20.9 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KDO26012.1 - 0.00065 19.0 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MeaB PF03308.16 KDO26012.1 - 0.0044 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KDO26012.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Dynamin family VWA_CoxE PF05762.14 KDO26012.1 - 0.039 13.3 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein SHMT PF00464.19 KDO26013.1 - 1e-199 663.2 0.0 1.2e-199 662.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KDO26013.1 - 1.7e-05 24.2 0.0 3.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II KKLCAg1 PF15204.6 KDO26013.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Bromodomain PF00439.25 KDO26014.1 - 1.7e-15 56.8 0.0 4.6e-14 52.3 0.0 2.7 2 1 0 2 2 2 1 Bromodomain ASXH PF13919.6 KDO26014.1 - 0.0062 16.6 0.1 0.0095 16.0 0.1 1.3 1 0 0 1 1 1 1 Asx homology domain EccE PF11203.8 KDO26014.1 - 0.084 13.2 0.3 0.16 12.3 0.0 1.5 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PSS PF03034.15 KDO26015.1 - 1.1e-83 281.1 8.9 1.6e-83 280.6 8.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase eIF2A PF08662.11 KDO26016.1 - 1.2e-72 243.8 0.0 3.2e-69 232.7 0.0 3.3 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KDO26016.1 - 0.085 12.8 2.8 2.9 8.0 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PX PF00787.24 KDO26017.1 - 6.3e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Peptidase_M8 PF01457.16 KDO26018.1 - 1.7e-70 238.2 21.3 1.7e-51 175.6 9.0 4.0 2 2 2 4 4 4 3 Leishmanolysin EGF_2 PF07974.13 KDO26018.1 - 0.0024 18.2 14.9 0.0024 18.2 14.9 4.3 4 1 0 4 4 4 1 EGF-like domain cEGF PF12662.7 KDO26018.1 - 2.1 8.4 14.9 3.6 7.6 3.1 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Peptidase_M8 PF01457.16 KDO26019.1 - 4e-58 197.4 8.3 5.7e-43 147.4 5.6 2.5 2 1 0 2 2 2 2 Leishmanolysin Aspzincin_M35 PF14521.6 KDO26019.1 - 0.095 13.2 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase LisH PF08513.11 KDO26020.1 - 8.7e-05 22.3 0.1 0.00025 20.9 0.1 1.9 1 0 0 1 1 1 1 LisH LisH_TPL PF17814.1 KDO26020.1 - 0.048 13.3 0.3 0.22 11.2 0.1 2.3 2 0 0 2 2 2 0 LisH-like dimerisation domain Ubie_methyltran PF01209.18 KDO26021.1 - 1.5e-82 276.4 0.0 1.8e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KDO26021.1 - 5.1e-18 65.6 0.1 1.5e-16 60.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO26021.1 - 5e-17 62.3 0.0 1.1e-15 58.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO26021.1 - 1.1e-12 48.1 0.0 2.1e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO26021.1 - 1.7e-08 34.5 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO26021.1 - 4.1e-08 33.9 0.0 9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KDO26021.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase TPR_1 PF00515.28 KDO26022.1 - 4e-109 352.4 22.4 3.6e-09 36.1 0.2 13.5 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26022.1 - 3.4e-91 292.2 31.1 3.1e-08 33.1 0.1 13.7 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26022.1 - 6.9e-82 268.9 40.9 7.6e-10 38.3 2.7 13.7 2 2 12 14 14 14 13 TPR repeat TPR_17 PF13431.6 KDO26022.1 - 3.2e-64 208.8 32.3 5.3e-06 26.5 0.4 14.2 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26022.1 - 1.1e-62 203.1 10.1 9e-06 25.5 0.1 13.3 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26022.1 - 1.7e-43 147.0 39.2 7.6e-09 36.1 4.0 8.4 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_9 PF13371.6 KDO26022.1 - 6e-42 141.7 17.6 9.3e-08 32.1 0.1 8.9 2 2 5 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26022.1 - 6.5e-37 125.7 26.1 3.4e-08 33.7 0.3 8.8 5 3 4 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26022.1 - 2.3e-29 99.2 22.7 0.0061 16.5 0.0 14.0 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26022.1 - 1.1e-25 88.5 24.1 0.048 14.3 0.5 13.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_14 PF13428.6 KDO26022.1 - 9.8e-25 85.1 26.0 0.0085 16.8 0.1 12.6 3 2 11 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26022.1 - 1.9e-18 66.7 24.9 0.01 16.3 0.5 8.9 4 3 5 10 10 10 7 Tetratricopeptide repeat SHNi-TPR PF10516.9 KDO26022.1 - 2.7e-16 58.7 19.8 0.19 11.2 0.1 12.5 13 0 0 13 13 13 4 SHNi-TPR TPR_10 PF13374.6 KDO26022.1 - 2.2e-15 56.0 37.2 0.083 12.8 0.1 11.6 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_15 PF13429.6 KDO26022.1 - 3e-10 39.8 16.0 0.047 12.9 0.0 8.8 2 2 8 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO26022.1 - 2.5e-06 27.6 17.0 0.2 11.9 0.2 6.1 4 3 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KDO26022.1 - 7.7e-06 25.1 7.9 1.6 7.5 0.2 4.8 3 1 2 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KDO26022.1 - 1.8e-05 24.9 0.6 1.2e+02 3.7 0.1 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Ubiq-assoc PF09145.10 KDO26022.1 - 0.0004 20.3 0.7 10 6.2 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-associated Fis1_TPR_C PF14853.6 KDO26022.1 - 0.0075 16.3 14.8 8 6.6 0.1 6.8 8 0 0 8 8 6 0 Fis1 C-terminal tetratricopeptide repeat DUF1358 PF07096.11 KDO26022.1 - 0.015 15.2 0.1 0.28 11.2 0.0 3.1 3 2 2 5 5 4 0 Protein of unknown function (DUF1358) MIT PF04212.18 KDO26022.1 - 0.023 14.7 19.5 2.7 8.1 0.0 8.5 10 1 1 11 11 10 0 MIT (microtubule interacting and transport) domain MtrB PF05440.12 KDO26022.1 - 0.033 14.6 0.3 1.1e+02 3.3 0.0 4.5 3 1 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B BTAD PF03704.17 KDO26022.1 - 0.047 14.1 10.3 0.36 11.3 1.2 5.2 2 2 4 6 6 5 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 KDO26022.1 - 0.072 13.4 20.0 0.57 10.5 0.3 6.2 4 3 1 7 7 6 0 Tetratricopeptide repeat rve_2 PF13333.6 KDO26022.1 - 0.17 12.1 2.8 15 5.8 0.0 4.2 4 0 0 4 4 3 0 Integrase core domain Flp_C PF05202.12 KDO26022.1 - 2.1 7.8 5.1 21 4.6 0.2 3.0 3 0 0 3 3 3 0 Recombinase Flp protein TPR_21 PF09976.9 KDO26022.1 - 3 7.5 19.6 4.2 7.0 0.2 6.0 3 2 2 6 6 6 0 Tetratricopeptide repeat-like domain GlcNAc PF11397.8 KDO26023.1 - 1.2e-47 163.0 0.0 4.4e-39 134.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Asp PF00026.23 KDO26024.1 - 4.5e-23 82.2 2.2 1.9e-21 76.8 2.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO26024.1 - 5e-15 56.2 1.7 8.6e-15 55.4 1.7 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO26024.1 - 9.4e-10 38.5 0.4 5.1e-08 32.8 0.1 3.2 3 1 0 3 3 3 1 Xylanase inhibitor C-terminal Astacin PF01400.24 KDO26026.1 - 1.5e-14 54.0 0.4 1.2e-12 47.8 0.4 2.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M11 PF05548.11 KDO26026.1 - 0.11 11.6 0.5 0.17 11.0 0.5 1.3 1 0 0 1 1 1 0 Gametolysin peptidase M11 Abhydrolase_1 PF00561.20 KDO26027.1 - 4e-09 36.5 0.1 7.6e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO26027.1 - 6.2e-06 25.6 0.1 0.00014 21.2 0.1 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KDO26027.1 - 0.0007 19.1 0.0 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KDO26027.1 - 0.0055 16.8 0.1 0.013 15.6 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein SDA1 PF05285.12 KDO26028.1 - 9.9e-49 166.6 45.3 3.9e-29 102.2 8.1 3.1 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 KDO26028.1 - 1.4e-22 79.7 0.3 4.2e-22 78.2 0.3 1.9 1 0 0 1 1 1 1 NUC130/3NT domain SlyX PF04102.12 KDO26029.1 - 0.067 13.8 2.0 0.38 11.4 0.5 2.6 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 KDO26029.1 - 0.19 12.1 3.0 6.7 7.1 1.1 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Wbp11 PF09429.10 KDO26030.1 - 0.053 13.9 2.0 0.11 12.9 2.0 1.5 1 0 0 1 1 1 0 WW domain binding protein 11 SlyX PF04102.12 KDO26030.1 - 0.092 13.4 0.6 0.31 11.7 0.4 1.9 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.10 KDO26030.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LPMO_10 PF03067.15 KDO26031.1 - 3e-22 80.2 1.0 3e-22 80.2 1.0 2.3 2 2 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_1 PF00734.18 KDO26031.1 - 3.6e-11 42.8 8.1 3.6e-11 42.8 8.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain PT PF04886.12 KDO26031.1 - 4e-10 39.1 42.2 4.7e-06 26.0 8.3 4.3 2 1 2 4 4 4 3 PT repeat Stk19 PF10494.9 KDO26033.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 Myb_DNA-binding PF00249.31 KDO26034.1 - 4.4e-16 58.8 5.4 4.9e-09 36.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO26034.1 - 5.6e-11 42.5 0.1 3e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO26034.1 - 0.0098 16.3 3.5 0.013 15.9 0.2 2.2 1 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Adap_comp_sub PF00928.21 KDO26036.1 - 1.1e-61 208.6 0.1 1.3e-61 208.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KDO26036.1 - 1.4e-08 34.8 0.1 2.6e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_12 PF13424.6 KDO26037.1 - 1.8e-07 31.4 19.4 0.0025 18.1 4.4 5.2 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26037.1 - 0.0034 18.0 8.6 0.38 11.4 1.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26037.1 - 0.0044 16.8 12.1 3.2 7.7 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat GATase_5 PF13507.6 KDO26037.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain TPR_2 PF07719.17 KDO26037.1 - 0.013 15.6 15.1 0.69 10.2 0.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat FAT PF02259.23 KDO26037.1 - 0.014 14.6 0.1 0.042 13.1 0.0 1.7 1 1 1 2 2 2 0 FAT domain TPR_10 PF13374.6 KDO26037.1 - 0.016 15.1 13.3 0.028 14.3 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat YjgF_endoribonc PF14588.6 KDO26037.1 - 0.036 14.2 0.8 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease Nif11 PF07862.11 KDO26037.1 - 0.14 12.5 0.8 24 5.3 0.0 3.0 3 0 0 3 3 3 0 Nif11 domain TPR_8 PF13181.6 KDO26037.1 - 0.24 11.7 5.6 2.2 8.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26037.1 - 5.1 7.7 7.3 30 5.3 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CS PF04969.16 KDO26038.1 - 0.09 13.8 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 CS domain Abhydrolase_1 PF00561.20 KDO26039.1 - 1.5e-07 31.3 0.1 7.4e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO26039.1 - 1.1e-05 25.4 0.1 4.8e-05 23.4 0.1 2.1 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KDO26039.1 - 0.00015 21.1 0.0 0.0052 16.1 0.0 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Adap_comp_sub PF00928.21 KDO26040.1 - 5.6e-64 216.1 0.0 7e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KDO26040.1 - 4.2e-09 36.5 0.0 7.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain cNMP_binding PF00027.29 KDO26041.1 - 5.7e-06 26.3 0.0 1.6e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Nitrophorin PF02087.15 KDO26041.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Nitrophorin DNA_pol_B PF00136.21 KDO26041.1 - 0.15 10.7 0.2 0.26 9.9 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase family B Aa_trans PF01490.18 KDO26042.1 - 3e-38 131.6 22.7 4.1e-38 131.2 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sigma_reg_N PF13800.6 KDO26042.1 - 0.22 11.8 0.1 0.22 11.8 0.1 4.5 5 0 0 5 5 5 0 Sigma factor regulator N-terminal Fumarate_red_D PF02313.17 KDO26042.1 - 0.32 11.1 0.1 0.32 11.1 0.1 4.0 4 0 0 4 4 4 0 Fumarate reductase subunit D Pox_LP_H2 PF03356.15 KDO26043.1 - 3.1e-08 33.7 1.4 0.031 14.1 0.0 4.1 4 0 0 4 4 4 4 Viral late protein H2 LRR_6 PF13516.6 KDO26044.1 - 1.6e-07 30.8 1.3 5e-05 23.0 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich repeat VPS9 PF02204.18 KDO26045.1 - 2.1e-10 40.7 0.0 8.7e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Prok-RING_1 PF14446.6 KDO26045.1 - 0.025 14.5 5.1 0.058 13.3 5.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KDO26045.1 - 0.065 13.1 6.4 0.12 12.2 6.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KDO26045.1 - 1.6 8.7 7.5 3.3 7.7 7.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KDO26045.1 - 3.1 8.2 8.6 7.3 7.0 8.6 1.7 1 0 0 1 1 1 0 Ring finger domain PDZ PF00595.24 KDO26046.1 - 0.0004 20.7 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Pox_VP8_L4R PF04498.12 KDO26046.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R NOA36 PF06524.12 KDO26047.1 - 0.011 15.1 3.0 0.017 14.5 3.0 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KDO26047.1 - 0.015 15.0 0.8 0.029 14.0 0.8 1.4 1 0 0 1 1 1 0 FAM176 family ORC6 PF05460.13 KDO26047.1 - 0.015 14.6 1.0 0.023 14.0 0.1 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) PBP1_TM PF14812.6 KDO26047.1 - 0.019 15.3 7.4 0.044 14.2 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.18 KDO26047.1 - 0.024 14.6 0.3 0.039 13.9 0.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 KDO26047.1 - 0.059 13.4 1.7 0.096 12.7 1.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KDO26047.1 - 0.14 10.2 2.7 0.19 9.8 2.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PA PF02225.22 KDO26047.1 - 0.16 12.1 3.6 0.35 10.9 1.1 2.4 2 0 0 2 2 2 0 PA domain Nucleo_P87 PF07267.11 KDO26047.1 - 0.27 10.0 1.7 0.4 9.5 1.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.14 KDO26047.1 - 0.6 9.9 5.7 0.94 9.2 5.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 KDO26047.1 - 0.71 10.3 9.3 1.5 9.3 9.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Shadoo PF14999.6 KDO26047.1 - 1 9.5 6.1 2.7 8.1 0.8 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Sporozoite_P67 PF05642.11 KDO26047.1 - 6.1 4.8 7.2 2.3 6.2 4.8 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Aa_trans PF01490.18 KDO26048.1 - 1.9e-28 99.3 18.3 2.7e-28 98.8 18.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0182 PF03699.13 KDO26048.1 - 0.49 8.5 6.0 0.79 7.8 6.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Aa_trans PF01490.18 KDO26049.1 - 6.4e-35 120.7 21.8 7.9e-35 120.3 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO26050.1 - 2.2e-38 132.0 29.3 3e-38 131.6 29.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO26051.1 - 1.1e-40 139.7 22.6 1.4e-40 139.3 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ilm1 PF10311.9 KDO26051.1 - 0.043 13.5 2.4 0.18 11.5 0.9 2.8 1 1 1 2 2 2 0 Increased loss of mitochondrial DNA protein 1 DUF5463 PF17551.2 KDO26051.1 - 0.1 12.5 3.1 0.13 12.2 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5463) Aa_trans PF01490.18 KDO26052.1 - 6.4e-20 71.2 13.2 8.8e-20 70.8 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26052.1 - 8.6e-07 28.3 9.3 1.6e-06 27.4 9.3 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Ilm1 PF10311.9 KDO26052.1 - 0.011 15.5 0.1 0.054 13.1 0.1 2.0 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Aa_trans PF01490.18 KDO26053.1 - 8.2e-11 41.2 3.7 9.7e-11 41.0 3.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Na_sulph_symp PF00939.19 KDO26053.1 - 0.024 13.7 3.3 0.035 13.1 3.3 1.2 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region TssN PF17555.2 KDO26053.1 - 0.064 12.6 2.1 0.085 12.2 2.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN Bax1-I PF01027.20 KDO26053.1 - 0.11 12.3 6.0 0.15 11.9 6.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Aa_trans PF01490.18 KDO26054.1 - 1.5e-38 132.6 23.2 1.9e-38 132.3 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO26055.1 - 6.3e-39 133.8 25.3 7.8e-39 133.5 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26055.1 - 4.3e-05 22.7 15.8 4.3e-05 22.7 15.8 2.7 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 KDO26056.1 - 8e-30 103.8 9.1 1e-29 103.5 9.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26056.1 - 2.9e-09 36.5 7.1 5.5e-09 35.6 7.1 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AMP-binding PF00501.28 KDO26057.1 - 2.8e-59 200.8 0.0 3.7e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KDO26058.1 - 3.7e-76 256.4 0.1 5.9e-76 255.7 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.21 KDO26058.1 - 1.8e-40 139.3 0.1 3.5e-40 138.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PP-binding PF00550.25 KDO26058.1 - 1.2e-07 32.0 0.0 3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aminotran_5 PF00266.19 KDO26058.1 - 0.0034 16.4 0.1 0.0061 15.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KDO26058.1 - 0.015 13.8 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KDO26058.1 - 0.042 13.1 0.3 0.08 12.2 0.3 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding_C_2 PF14535.6 KDO26058.1 - 0.046 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain OKR_DC_1 PF01276.20 KDO26058.1 - 0.059 12.1 0.4 0.22 10.2 0.1 2.0 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Toprim_2 PF13155.6 KDO26058.1 - 0.1 13.0 0.2 0.94 9.9 0.1 2.5 2 0 0 2 2 2 0 Toprim-like AMP-binding PF00501.28 KDO26059.1 - 5.1e-84 282.3 0.0 1.3e-83 281.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KDO26059.1 - 2.1e-07 31.2 0.0 6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.6 KDO26059.1 - 0.02 15.2 0.3 0.09 13.1 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ACBP PF00887.19 KDO26060.1 - 4.8e-14 52.3 0.0 9.5e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Cmyb_C PF09316.10 KDO26060.1 - 0.028 14.1 0.3 0.041 13.6 0.3 1.3 1 0 0 1 1 1 0 C-myb, C-terminal ATP-grasp_4 PF13535.6 KDO26061.1 - 4.1e-21 75.2 0.0 4.6e-09 36.1 0.0 3.4 2 1 0 2 2 2 2 ATP-grasp domain LAL_C2 PF18603.1 KDO26061.1 - 6.8e-15 55.0 0.0 6.9e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 ATP-grasp_3 PF02655.14 KDO26061.1 - 9.5e-13 48.5 0.0 9.5e-06 25.8 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KDO26061.1 - 2.6e-09 36.9 0.0 0.0029 17.3 0.0 3.3 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KDO26061.1 - 3.7e-09 36.6 0.0 0.00025 20.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KDO26061.1 - 3.7e-05 23.4 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Polysacc_deac_1 PF01522.21 KDO26063.1 - 0.019 14.9 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase Pyr_excise PF03013.14 KDO26063.1 - 0.16 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Polysacc_deac_1 PF01522.21 KDO26064.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Aa_trans PF01490.18 KDO26065.1 - 2.3e-41 141.8 21.3 3.1e-41 141.4 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26065.1 - 2e-08 33.7 7.9 2e-08 33.7 7.9 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 KDO26066.1 - 2.7e-34 118.6 23.5 3.2e-34 118.3 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sigma_reg_N PF13800.6 KDO26066.1 - 9.4 6.6 0.0 9.4 6.6 0.0 4.0 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Aa_trans PF01490.18 KDO26067.1 - 9.9e-41 139.8 22.4 1.2e-40 139.5 22.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO26068.1 - 3.7e-35 121.4 24.9 4.8e-35 121.0 24.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26068.1 - 0.012 14.7 29.5 0.042 12.9 15.6 2.8 2 1 0 2 2 2 0 Tryptophan/tyrosine permease family Polysacc_deac_1 PF01522.21 KDO26069.1 - 0.0037 17.2 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 KDO26070.1 - 0.018 14.9 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase BTB_2 PF02214.22 KDO26071.1 - 5.5e-13 49.1 0.0 8.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KDO26071.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain zf-BED PF02892.15 KDO26071.1 - 0.036 14.1 2.6 0.066 13.2 2.6 1.4 1 0 0 1 1 1 0 BED zinc finger MFS_1 PF07690.16 KDO26073.1 - 4e-07 29.3 12.7 5.4e-07 28.9 12.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KDO26074.1 - 1.2e-12 47.5 25.8 1.2e-12 47.5 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KDO26075.1 - 6.9e-13 48.2 31.2 6.9e-13 48.2 31.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TPR_6 PF13174.6 KDO26076.1 - 0.18 12.5 0.4 58 4.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FYVE PF01363.21 KDO26077.1 - 5.7e-16 58.4 8.1 1e-15 57.6 8.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO26077.1 - 0.0012 19.1 5.3 0.002 18.3 5.3 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4667 PF15700.5 KDO26077.1 - 0.01 16.0 6.4 0.019 15.1 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) zf-Sec23_Sec24 PF04810.15 KDO26077.1 - 1.6 8.8 8.4 3.4 7.8 3.8 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2HC5 PF06221.13 KDO26077.1 - 7.6 6.6 9.7 24 5.0 9.7 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SYCE1 PF15233.6 KDO26078.1 - 5.4e-05 23.3 4.3 5.4e-05 23.3 4.3 6.5 4 2 2 6 6 6 2 Synaptonemal complex central element protein 1 TPR_MLP1_2 PF07926.12 KDO26078.1 - 0.0032 17.5 12.2 0.0032 17.5 12.2 9.0 8 2 2 11 11 11 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KDO26078.1 - 0.023 14.7 47.4 0.02 14.9 5.9 7.0 2 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KDO26078.1 - 0.24 10.3 66.9 0.039 12.8 10.0 6.5 3 2 3 6 6 6 0 Spc7 kinetochore protein Filament PF00038.21 KDO26078.1 - 0.55 9.8 41.6 0.27 10.8 3.7 5.2 3 1 2 5 5 5 0 Intermediate filament protein ATG16 PF08614.11 KDO26078.1 - 1.5 9.0 99.9 0.018 15.3 10.6 7.8 2 2 6 9 9 9 0 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KDO26078.1 - 1.6 7.8 48.0 0.25 10.4 7.1 4.3 2 1 2 4 4 4 0 CCDC144C protein coiled-coil region End3 PF12761.7 KDO26078.1 - 1.9 8.6 24.6 2.4 8.3 7.9 5.0 3 2 1 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 JIP_LZII PF16471.5 KDO26078.1 - 8.3 6.7 34.4 20 5.5 0.2 9.5 8 2 3 11 11 11 0 JNK-interacting protein leucine zipper II SHE3 PF17078.5 KDO26079.1 - 0.00043 20.1 66.1 0.17 11.6 7.3 9.5 3 2 5 8 8 8 5 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 KDO26079.1 - 0.00085 19.6 40.3 0.003 17.8 21.9 12.6 2 2 9 12 12 10 6 Autophagy protein 16 (ATG16) Filament PF00038.21 KDO26079.1 - 0.0011 18.6 128.4 0.0088 15.7 14.9 8.6 2 2 3 7 7 6 5 Intermediate filament protein DUF1664 PF07889.12 KDO26079.1 - 0.0013 18.7 71.7 0.0036 17.3 2.2 12.0 5 3 8 14 14 13 6 Protein of unknown function (DUF1664) HrpB7 PF09486.10 KDO26079.1 - 0.0025 18.2 20.9 0.0025 18.2 20.9 14.1 2 2 13 15 15 12 4 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 KDO26079.1 - 0.01 16.3 8.2 0.01 16.3 8.2 10.8 1 1 10 11 11 10 0 Fez1 TACC_C PF05010.14 KDO26079.1 - 0.022 14.6 0.4 0.022 14.6 0.4 8.2 2 1 4 7 7 6 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1494 PF07379.11 KDO26079.1 - 0.034 14.0 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1494) Fib_alpha PF08702.10 KDO26079.1 - 0.041 14.1 50.5 0.33 11.1 0.6 10.2 5 3 7 12 12 12 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KDO26079.1 - 0.095 11.6 153.7 0.013 14.4 10.7 11.0 1 1 7 10 10 9 0 Spc7 kinetochore protein MPS2 PF17060.5 KDO26079.1 - 0.68 9.1 37.9 0.31 10.2 3.1 6.9 4 4 3 7 7 7 0 Monopolar spindle protein 2 Snapin_Pallidin PF14712.6 KDO26079.1 - 1.6 9.2 67.0 0.27 11.7 0.3 13.4 7 4 4 14 14 14 0 Snapin/Pallidin Alpha-amylase PF00128.24 KDO26079.1 - 2.1 7.8 8.5 0.09 12.3 0.5 2.6 2 0 0 2 2 2 0 Alpha amylase, catalytic domain PKcGMP_CC PF16808.5 KDO26079.1 - 3 7.8 11.6 1.2 9.1 0.0 6.4 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PI3K_P85_iSH2 PF16454.5 KDO26079.1 - 5.2 6.6 61.3 1.4 8.5 3.7 11.0 6 4 4 10 10 10 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PCI PF01399.27 KDO26080.1 - 1.6e-08 35.0 0.1 2.5e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 PCI domain Biotin_carb_C PF02785.19 KDO26080.1 - 0.0077 16.3 0.2 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CSN7a_helixI PF18392.1 KDO26080.1 - 0.058 13.3 1.1 0.1 12.5 0.3 1.8 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Phage_TTP_1 PF04630.12 KDO26080.1 - 0.089 12.1 0.2 0.21 10.9 0.2 1.6 2 0 0 2 2 2 0 Phage tail tube protein F-box PF00646.33 KDO26081.1 - 0.00029 20.6 0.0 0.00069 19.4 0.0 1.6 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KDO26081.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 F-box Ank_2 PF12796.7 KDO26083.1 - 6.5e-27 93.9 8.1 3.9e-15 56.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26083.1 - 4.9e-21 74.5 5.3 4.9e-11 42.7 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO26083.1 - 2e-20 72.3 8.3 7.3e-11 42.0 0.0 6.7 6 1 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KDO26083.1 - 1.2e-19 70.3 2.9 1.1e-11 45.0 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26083.1 - 2.4e-18 64.3 1.8 2.7e-08 33.4 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat ABC_tran PF00005.27 KDO26084.1 - 4.5e-28 98.5 0.0 7.2e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO26084.1 - 2.6e-24 86.3 11.9 5.2e-24 85.4 11.9 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO26084.1 - 1.8e-06 27.6 0.2 0.00028 20.4 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO26084.1 - 2.4e-06 27.6 0.0 5.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KDO26084.1 - 0.00013 21.9 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO26084.1 - 0.00035 21.0 0.2 0.0016 18.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO26084.1 - 0.00043 20.6 0.0 0.0023 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KDO26084.1 - 0.00061 18.7 0.2 0.25 10.1 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Septin PF00735.18 KDO26084.1 - 0.0043 16.4 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_23 PF13476.6 KDO26084.1 - 0.0075 16.8 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KDO26084.1 - 0.011 16.2 0.0 0.059 13.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KDO26084.1 - 0.012 15.3 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO26084.1 - 0.036 14.1 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KDO26084.1 - 0.055 13.7 0.2 0.28 11.4 0.1 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Herpes_Helicase PF02689.14 KDO26084.1 - 0.063 11.2 0.0 0.09 10.7 0.0 1.1 1 0 0 1 1 1 0 Helicase NACHT PF05729.12 KDO26084.1 - 0.064 13.2 0.2 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KDO26084.1 - 0.067 12.8 0.1 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO26084.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.25 KDO26084.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 KDO26084.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Erv26 PF04148.13 KDO26087.1 - 0.05 13.4 1.6 0.098 12.5 1.6 1.5 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 CPL PF08144.11 KDO26088.1 - 1.4e-14 54.6 1.8 1.5e-12 48.1 0.0 4.1 3 2 1 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 KDO26088.1 - 9.5e-06 25.0 0.0 0.41 10.4 0.0 4.4 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat DUF4071 PF13281.6 KDO26088.1 - 0.027 13.5 0.5 0.045 12.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) SPRY PF00622.28 KDO26089.1 - 3.8e-11 43.2 0.0 6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 KDO26089.1 - 0.00095 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KDO26089.1 - 0.0045 16.9 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 F-box SDA1 PF05285.12 KDO26089.1 - 0.067 12.6 12.7 0.086 12.3 12.7 1.1 1 0 0 1 1 1 0 SDA1 PFU PF09070.11 KDO26090.1 - 0.041 14.1 0.0 18 5.7 0.0 3.4 4 0 0 4 4 4 0 PFU (PLAA family ubiquitin binding) Myosin-VI_CBD PF16521.5 KDO26090.1 - 0.12 12.3 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Myosin VI cargo binding domain Lyase_1 PF00206.20 KDO26091.1 - 1e-114 383.2 0.0 1.3e-114 382.8 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KDO26091.1 - 5.6e-26 90.7 1.2 7.4e-26 90.3 0.1 1.9 2 0 0 2 2 2 1 Fumarase C C-terminus Aldedh PF00171.22 KDO26093.1 - 7.3e-34 117.1 0.0 9.6e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KDO26094.1 - 1.5e-60 205.1 0.0 2.1e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KDO26095.1 - 1e-65 222.1 0.0 1.2e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mito_carr PF00153.27 KDO26096.1 - 3.1e-65 216.1 4.3 6.3e-21 74.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TIR_2 PF13676.6 KDO26097.1 - 1.6e-11 44.9 0.0 3.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain Laminin_G_3 PF13385.6 KDO26097.1 - 5.9e-06 26.5 0.1 0.16 12.1 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily CTD_bind PF04818.13 KDO26098.1 - 4.4e-11 43.4 0.0 1.5e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Thioredoxin_12 PF18400.1 KDO26098.1 - 0.042 13.7 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain PilM PF07419.12 KDO26100.1 - 0.018 15.2 0.2 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 PilM DUSP PF06337.12 KDO26101.1 - 8.4e-15 55.2 0.0 1.4e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 KDO26101.1 - 7.8e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KDO26102.1 - 0.19 12.3 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 PH domain LRR_6 PF13516.6 KDO26104.1 - 4.8e-34 113.5 27.5 0.00031 20.5 0.1 14.9 16 0 0 16 16 16 9 Leucine Rich repeat LRR_4 PF12799.7 KDO26104.1 - 1.9e-10 40.8 18.6 0.093 13.2 0.0 9.7 7 5 4 11 11 11 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO26104.1 - 8.8e-09 34.7 8.6 12 6.9 0.0 10.8 14 0 0 14 14 14 2 Leucine Rich Repeat LRR_8 PF13855.6 KDO26104.1 - 1.3e-05 24.8 18.5 4.6 7.1 0.0 10.7 8 4 3 11 11 11 2 Leucine rich repeat Snf7 PF03357.21 KDO26104.1 - 0.0071 16.0 0.7 0.021 14.4 0.7 1.9 1 0 0 1 1 1 1 Snf7 HTH_26 PF13443.6 KDO26104.1 - 0.021 15.3 0.0 13 6.3 0.0 3.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Protein_K PF12283.8 KDO26104.1 - 0.026 14.7 0.6 14 6.0 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage protein K LRR_2 PF07723.13 KDO26104.1 - 0.84 10.4 6.1 15 6.4 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 KDO26105.1 - 5.4e-70 235.8 0.0 6.4e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26105.1 - 2.5e-30 105.6 0.0 3.5e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO26105.1 - 0.023 14.1 0.1 0.047 13.0 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KDO26105.1 - 0.076 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GTP1_OBG PF01018.22 KDO26106.1 - 3.2e-33 114.5 5.2 4.7e-33 114.0 5.2 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KDO26106.1 - 1.1e-23 83.5 0.0 4.4e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO26106.1 - 7.7e-09 35.3 0.0 3.4e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KDO26106.1 - 2.4e-05 23.9 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_C PF08438.10 KDO26106.1 - 0.024 15.2 0.0 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 GTPase of unknown function C-terminal AAA_18 PF13238.6 KDO26106.1 - 0.038 14.5 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO26106.1 - 0.064 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 KDO26106.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KDO26106.1 - 0.13 12.3 0.0 9.2 6.3 0.0 2.7 3 0 0 3 3 3 0 Dynamin family cobW PF02492.19 KDO26106.1 - 0.14 11.8 0.0 8.6 5.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain YL1 PF05764.13 KDO26106.1 - 3.2 7.8 9.5 4.8 7.2 9.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 KDO26106.1 - 6 5.0 8.8 8.9 4.4 8.8 1.2 1 0 0 1 1 1 0 Nop14-like family 2OG-FeII_Oxy PF03171.20 KDO26107.1 - 2.9e-05 24.5 0.0 6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEC-1_N PF04625.13 KDO26107.1 - 0.049 12.6 0.1 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Nop PF01798.18 KDO26108.1 - 2.8e-66 223.3 0.0 4.3e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KDO26108.1 - 8.7e-37 126.7 5.4 1.7e-35 122.5 5.8 2.4 2 0 0 2 2 2 1 Prp31 C terminal domain DUF3236 PF11576.8 KDO26108.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Methyltransf_16 PF10294.9 KDO26109.1 - 4.4e-29 101.4 0.0 6.4e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KDO26109.1 - 0.0047 16.8 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO26109.1 - 0.011 15.1 0.2 0.015 14.7 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RAB3GAP2_N PF14655.6 KDO26110.1 - 1.1e-47 163.2 0.0 2.2e-38 132.6 0.0 2.2 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 KDO26110.1 - 4.7e-13 48.3 0.0 6.4e-08 31.3 0.0 2.9 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit C-terminus Methyltransf_25 PF13649.6 KDO26111.1 - 6.5e-11 42.8 0.0 1.9e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO26111.1 - 2.9e-09 36.7 0.4 2.9e-09 36.7 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO26111.1 - 4.4e-08 33.7 0.0 1.7e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO26111.1 - 2e-07 30.9 0.1 5.2e-07 29.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO26111.1 - 1.5e-06 28.2 0.0 3.2e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO26111.1 - 2.4e-05 23.8 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KDO26111.1 - 3e-05 23.1 0.1 8.2e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KDO26111.1 - 0.00023 20.8 0.1 0.00044 19.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KDO26111.1 - 0.00041 21.1 0.0 0.0015 19.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KDO26111.1 - 0.0043 17.0 0.2 0.0075 16.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KDO26111.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase zf-C2H2_2 PF12756.7 KDO26111.1 - 0.026 14.8 0.7 0.086 13.2 0.3 2.0 3 0 0 3 3 2 0 C2H2 type zinc-finger (2 copies) Spc24 PF08286.11 KDO26111.1 - 0.027 14.7 0.5 0.042 14.1 0.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Methyltransf_32 PF13679.6 KDO26111.1 - 0.035 14.1 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KDO26111.1 - 0.038 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KDO26111.1 - 0.059 12.8 0.3 0.37 10.2 0.2 2.3 2 1 1 3 3 3 0 Tellurite resistance protein TehB DivIC PF04977.15 KDO26111.1 - 0.24 11.2 1.1 0.55 10.0 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Lipase_3 PF01764.25 KDO26112.1 - 1.4e-28 99.5 0.0 5.1e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 KDO26112.1 - 0.0049 16.4 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) SIT PF15330.6 KDO26112.1 - 0.011 16.1 1.2 0.028 14.8 0.1 2.3 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Abhydrolase_6 PF12697.7 KDO26112.1 - 0.017 15.8 0.1 0.059 14.0 0.1 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pox_A14 PF05767.12 KDO26112.1 - 1 9.6 6.6 0.28 11.4 2.3 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Methyltransf_16 PF10294.9 KDO26113.1 - 1.7e-18 67.0 0.1 2.8e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO26113.1 - 3.3e-06 26.7 0.1 1.2e-05 25.0 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KDO26113.1 - 8.2e-06 25.4 0.0 1.2e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO26113.1 - 0.00016 22.3 0.0 0.00031 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO26113.1 - 0.00092 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO26113.1 - 0.0065 16.3 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO26113.1 - 0.012 16.2 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KDO26113.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KDO26113.1 - 0.038 14.7 0.0 0.065 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KDO26113.1 - 0.054 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 KDO26113.1 - 0.061 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 KDO26113.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ank_2 PF12796.7 KDO26114.1 - 3.7e-16 59.5 0.2 5.3e-11 43.0 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) FYVE PF01363.21 KDO26114.1 - 6.6e-15 55.0 4.6 1.3e-14 54.0 4.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 KDO26114.1 - 2.2e-12 47.0 4.5 0.0021 18.4 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26114.1 - 5.9e-11 41.6 1.3 0.41 11.3 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KDO26114.1 - 5.4e-09 36.4 2.8 0.0031 18.1 0.5 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO26114.1 - 8.5e-08 32.3 7.3 0.0028 18.1 0.3 5.0 5 0 0 5 5 5 2 Ankyrin repeat FYVE_2 PF02318.16 KDO26114.1 - 0.004 17.4 2.1 0.0068 16.6 2.1 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger TTL PF03133.15 KDO26115.1 - 1.7e-72 244.0 0.0 4.4e-72 242.7 0.0 1.6 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO26115.1 - 7.7e-07 28.6 0.0 0.00014 21.2 0.0 2.9 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO26115.1 - 0.00068 19.0 0.0 0.067 12.4 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF4208 PF13907.6 KDO26116.1 - 4.5e-11 43.0 0.0 9.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DUF3658 PF12395.8 KDO26116.1 - 0.086 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function SLIDE PF09111.10 KDO26116.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 SLIDE MFMR_assoc PF16596.5 KDO26116.1 - 2.5 8.6 14.4 0.53 10.8 10.2 1.9 2 0 0 2 2 2 0 Disordered region downstream of MFMR LtrA PF06772.11 KDO26118.1 - 5e-33 114.8 31.1 6.5e-33 114.4 31.1 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2431 PF10354.9 KDO26119.1 - 9.7e-36 123.6 0.0 1.5e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) LtrA PF06772.11 KDO26119.1 - 2.6e-31 109.1 39.9 1.1e-23 84.1 27.9 2.2 1 1 1 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) FDX-ACB PF03147.14 KDO26119.1 - 0.021 15.3 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain SID-1_RNA_chan PF13965.6 KDO26119.1 - 0.12 10.7 3.9 0.041 12.3 0.6 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ABC2_membrane_4 PF12730.7 KDO26119.1 - 1.2 9.1 12.1 0.29 11.1 2.7 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein Myosin-VI_CBD PF16521.5 KDO26119.1 - 1.3 9.1 4.1 25 5.0 0.3 2.4 2 0 0 2 2 2 0 Myosin VI cargo binding domain OEP PF02321.18 KDO26120.1 - 0.0084 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Outer membrane efflux protein Phage_GP20 PF06810.11 KDO26120.1 - 0.057 13.2 2.4 0.082 12.7 2.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 AAA_13 PF13166.6 KDO26120.1 - 0.12 11.1 1.1 0.14 10.8 1.1 1.0 1 0 0 1 1 1 0 AAA domain FTCD_C PF04961.12 KDO26120.1 - 0.34 10.7 3.5 0.48 10.2 3.5 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Mis14 PF08641.12 KDO26120.1 - 0.63 10.4 3.7 12 6.2 3.7 2.2 1 1 0 1 1 1 0 Kinetochore protein Mis14 like DUF2310 PF10071.9 KDO26121.1 - 0.21 10.8 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) TMEM154 PF15102.6 KDO26122.1 - 0.0019 18.1 0.5 0.0035 17.3 0.5 1.4 1 0 0 1 1 1 1 TMEM154 protein family Cytomega_TRL10 PF06084.11 KDO26122.1 - 0.0067 16.5 0.1 0.0096 15.9 0.1 1.2 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein DUF5305 PF17231.2 KDO26122.1 - 0.051 13.0 0.5 0.081 12.3 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 KDO26122.1 - 0.26 11.2 0.0 0.33 10.8 0.0 1.1 1 0 0 1 1 1 0 Rifin MGC-24 PF05283.11 KDO26122.1 - 0.28 11.6 7.1 0.48 10.9 7.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KDO26126.1 - 0.0039 17.1 0.8 0.0039 17.1 0.8 2.1 2 1 0 2 2 2 1 TMEM154 protein family DUF4366 PF14283.6 KDO26126.1 - 0.11 12.6 0.6 0.55 10.3 0.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4310 PF14187.6 KDO26126.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) DUF5336 PF17270.2 KDO26126.1 - 0.44 10.2 0.0 0.44 10.2 0.0 4.3 5 1 0 5 5 5 0 Family of unknown function (DUF5336) DEAD PF00270.29 KDO26127.1 - 2.7e-39 134.8 0.0 6.3e-39 133.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO26127.1 - 3.6e-22 78.8 0.1 4.4e-20 72.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO26127.1 - 3.1e-09 37.1 0.0 5.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KDO26127.1 - 0.024 14.9 0.1 3.9 7.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.14 KDO26127.1 - 0.069 13.1 0.2 0.19 11.7 0.2 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain MFS_5 PF05631.14 KDO26128.1 - 6.6e-72 242.4 8.5 8.9e-72 241.9 8.5 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KDO26128.1 - 4.3e-17 62.1 31.2 4.3e-17 62.1 31.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM238 PF15125.6 KDO26128.1 - 0.29 11.3 4.8 0.4 10.9 0.3 3.1 3 0 0 3 3 3 0 TMEM238 protein family Synaptobrevin PF00957.21 KDO26129.1 - 8.4e-27 92.8 0.4 1.5e-26 92.0 0.4 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KDO26129.1 - 4.3e-09 36.3 0.3 9.2e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain Sigma_reg_N PF13800.6 KDO26129.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF1947 PF09183.10 KDO26129.1 - 0.18 12.1 2.4 16 5.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) bZIP_1 PF00170.21 KDO26131.1 - 5e-08 32.9 11.2 9.2e-08 32.1 11.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO26131.1 - 7.1e-05 22.8 16.6 0.00014 21.9 16.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KDO26131.1 - 0.0037 17.7 9.1 0.0082 16.6 9.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Atg14 PF10186.9 KDO26131.1 - 0.19 10.8 3.5 0.28 10.2 3.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Aft1_HRA PF11786.8 KDO26131.1 - 0.68 10.3 11.1 1 9.7 7.3 3.1 3 1 1 4 4 4 0 Aft1 HRA domain DUF2431 PF10354.9 KDO26133.1 - 1e-29 104.0 0.0 1.4e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 KDO26133.1 - 0.00091 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DEAD PF00270.29 KDO26135.1 - 1e-45 155.6 1.3 2.5e-45 154.4 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO26135.1 - 2.1e-20 73.1 0.0 2e-19 69.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KDO26135.1 - 2.9e-18 65.9 0.1 5.3e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KDO26135.1 - 3.3e-06 27.2 0.5 2.2e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KDO26135.1 - 0.031 14.0 1.5 0.17 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KDO26135.1 - 0.29 11.4 1.3 1.6 9.0 0.0 2.7 4 0 0 4 4 4 0 AAA domain DIT1_PvcA PF05141.12 KDO26136.1 - 2.2e-78 263.5 0.0 2.3e-77 260.2 0.0 1.9 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.12 KDO26137.1 - 4e-68 229.9 0.0 2.5e-67 227.3 0.0 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KDO26137.1 - 8.6e-26 91.3 0.1 1.7e-25 90.3 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family IPPT PF01715.17 KDO26138.1 - 4.4e-66 223.0 0.0 6.4e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KDO26138.1 - 6.2e-06 25.8 0.1 1.1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 KDO26138.1 - 0.00012 22.2 0.1 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF3449 PF11931.8 KDO26138.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.8 KDO26138.1 - 0.0028 17.9 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 KDO26138.1 - 0.0091 16.5 0.2 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KDO26138.1 - 0.041 13.2 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KDO26138.1 - 0.069 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 KDO26138.1 - 0.081 13.0 0.4 0.23 11.5 0.9 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KDO26138.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase 2OG-FeII_Oxy_2 PF13532.6 KDO26139.1 - 2.3e-18 67.1 0.0 5.8e-18 65.8 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KDO26139.1 - 2.4e-08 34.5 0.0 6e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO26139.1 - 1.1e-06 29.2 0.0 3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO26139.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KDO26139.1 - 0.0031 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KDO26139.1 - 0.0056 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 KDO26139.1 - 0.006 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_12 PF08242.12 KDO26139.1 - 0.037 14.8 0.5 0.25 12.1 0.5 2.2 1 1 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.20 KDO26140.1 - 9.5e-05 22.9 0.0 0.0003 21.3 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain RCC1 PF00415.18 KDO26141.1 - 1.7e-45 153.4 34.3 4.9e-12 46.3 0.4 8.7 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO26141.1 - 1e-31 108.0 36.1 1e-10 41.1 0.5 7.9 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KDO26141.1 - 1.6e-10 41.4 0.2 3.2e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO26141.1 - 5.7e-07 29.7 4.1 0.00012 22.4 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO26141.1 - 6.3e-06 26.2 1.5 0.0064 16.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO26141.1 - 6.7e-06 26.3 0.5 3e-05 24.2 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO26141.1 - 8.3e-06 26.3 0.4 0.00089 19.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Radial_spoke_3 PF06098.11 KDO26142.1 - 1e-56 192.3 0.3 1.5e-56 191.8 0.3 1.2 1 0 0 1 1 1 1 Radial spoke protein 3 RasGAP_C PF03836.15 KDO26142.1 - 0.24 11.5 2.0 1.4 9.1 0.2 2.2 1 1 0 2 2 2 0 RasGAP C-terminus TauE PF01925.19 KDO26143.1 - 6.5e-23 81.6 41.2 1.1e-11 44.8 8.8 2.5 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE EB PF01683.18 KDO26143.1 - 0.11 12.8 0.5 0.2 12.0 0.5 1.3 1 0 0 1 1 1 0 EB module Sarcolipin PF05366.11 KDO26143.1 - 3.8 7.3 5.5 8.5 6.2 5.5 1.5 1 0 0 1 1 1 0 Sarcolipin Homoserine_dh PF00742.19 KDO26144.1 - 2e-28 99.4 0.0 3.8e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase SET PF00856.28 KDO26145.1 - 3.6e-11 43.7 0.0 9.2e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 SET domain AAA_26 PF13500.6 KDO26146.1 - 1.2e-35 123.1 0.0 1e-34 120.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KDO26146.1 - 8.6e-07 29.1 0.0 6.3e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 KDO26146.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 DRTGG domain DUF1611 PF07755.11 KDO26146.1 - 0.17 11.1 0.1 0.4 9.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain ER_lumen_recept PF00810.18 KDO26147.1 - 1.3e-51 175.3 8.5 1.3e-51 175.3 8.5 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KDO26147.1 - 0.02 14.6 0.1 0.02 14.6 0.1 4.1 4 1 1 5 5 5 0 PQ loop repeat Apq12 PF12716.7 KDO26147.1 - 6.3 6.8 9.4 0.18 11.8 0.7 2.7 3 0 0 3 3 3 0 Nuclear pore assembly and biogenesis CDC45 PF02724.14 KDO26148.1 - 0.01 14.2 4.6 0.017 13.4 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF924 PF06041.11 KDO26149.1 - 2.1e-16 60.6 0.0 2.7e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Fibroin_P25 PF07294.11 KDO26149.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Fibroin P25 HEAT PF02985.22 KDO26149.1 - 0.18 12.2 1.0 20 5.8 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat Pex24p PF06398.11 KDO26150.1 - 1.2e-09 37.6 0.1 1.6e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PDZ PF00595.24 KDO26150.1 - 1.5e-06 28.5 0.0 0.093 13.1 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KDO26150.1 - 1.7e-06 27.8 0.0 0.037 13.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO26150.1 - 0.12 12.7 0.0 2.5 8.5 0.0 2.3 1 1 1 2 2 2 0 PDZ domain SLATT_2 PF18183.1 KDO26151.1 - 0.0043 16.9 0.9 0.037 13.8 0.1 2.2 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain 2 HSF_DNA-bind PF00447.17 KDO26152.1 - 6.8e-24 84.3 0.9 6.8e-24 84.3 0.9 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding LtrA PF06772.11 KDO26153.1 - 1.1e-08 34.7 39.5 1.7e-08 34.1 39.5 1.3 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Tom7 PF08038.12 KDO26153.1 - 0.08 12.6 0.1 0.37 10.5 0.1 2.2 2 0 0 2 2 2 0 TOM7 family Pkinase_Tyr PF07714.17 KDO26154.1 - 5.1e-13 48.9 0.0 3.3e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26154.1 - 3.2e-12 46.4 0.0 7.7e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF2207 PF09972.9 KDO26154.1 - 0.019 13.8 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 KDO26154.1 - 0.093 12.3 0.1 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DAP10 PF07213.11 KDO26154.1 - 0.29 11.1 1.3 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 DAP10 membrane protein Lactamase_B_2 PF12706.7 KDO26157.1 - 0.0069 15.9 0.1 0.015 14.8 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BSMAP PF12280.8 KDO26157.1 - 0.0085 16.3 3.3 0.012 15.8 1.8 1.9 2 0 0 2 2 2 1 Brain specific membrane anchored protein zf-C2H2_3 PF13878.6 KDO26157.1 - 0.016 15.1 0.2 0.43 10.5 0.0 2.7 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Lactamase_B PF00753.27 KDO26157.1 - 0.029 14.4 0.7 0.062 13.3 0.7 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3222 PF11519.8 KDO26157.1 - 0.086 13.1 1.5 5.3 7.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) zf-ACC PF17848.1 KDO26158.1 - 0.0082 16.2 0.2 5.9 7.1 0.1 2.7 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KDO26158.1 - 0.078 12.4 0.9 3.7 7.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KDO26158.1 - 0.087 12.9 1.7 3.5 7.7 0.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon UPF0547 PF10571.9 KDO26158.1 - 0.83 9.8 4.5 3.8 7.7 0.3 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 EccE PF11203.8 KDO26158.1 - 1.9 8.9 7.6 19 5.7 0.3 3.4 3 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE PLDc_2 PF13091.6 KDO26159.1 - 3.4e-25 88.5 0.0 1.6e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 KDO26159.1 - 7.8e-22 77.8 0.0 1.7e-20 73.4 0.0 2.7 3 0 0 3 3 3 1 PLD-like domain PLDc PF00614.22 KDO26159.1 - 3.3e-12 46.1 3.2 1e-06 28.6 0.2 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif PhoLip_ATPase_C PF16212.5 KDO26161.1 - 1.1e-45 156.4 27.2 2.5e-45 155.2 17.6 3.2 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO26161.1 - 1.4e-19 69.5 1.8 1.7e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO26161.1 - 4.1e-15 56.7 1.3 2e-06 28.2 0.5 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO26161.1 - 1.5e-09 37.6 1.8 4.4e-09 36.1 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KDO26161.1 - 1.8e-07 31.1 0.0 1.2e-06 28.5 0.0 2.2 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KDO26161.1 - 0.00034 20.4 0.0 0.00083 19.2 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4055 PF13264.6 KDO26161.1 - 0.01 16.0 0.1 0.022 14.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) DsrH PF04077.12 KDO26161.1 - 0.016 15.3 0.4 12 6.1 0.0 3.4 3 0 0 3 3 3 0 DsrH like protein HAD PF12710.7 KDO26161.1 - 0.017 15.5 0.0 1 9.7 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase LPD3 PF18798.1 KDO26162.1 - 0.0062 16.8 1.1 0.043 14.1 0.0 2.5 1 1 3 4 4 4 1 Large polyvalent protein-associated domain 3 CbiC PF02570.15 KDO26162.1 - 0.024 14.3 0.5 0.024 14.3 0.5 1.9 2 1 0 2 2 2 0 Precorrin-8X methylmutase DUF1797 PF08796.10 KDO26162.1 - 0.085 12.9 0.2 0.27 11.4 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1797) Zincin_1 PF06262.11 KDO26162.1 - 0.23 11.6 3.0 0.32 11.1 0.6 2.4 2 1 0 2 2 2 0 Zincin-like metallopeptidase PEP-utilisers_N PF05524.13 KDO26162.1 - 0.39 10.9 13.8 0.32 11.2 3.0 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Phage_TAC_12 PF12363.8 KDO26162.1 - 0.46 10.9 4.0 0.67 10.4 0.6 2.7 2 2 0 2 2 2 0 Phage tail assembly chaperone protein, TAC EMP24_GP25L PF01105.24 KDO26163.1 - 3.6e-27 95.5 0.4 5.6e-27 94.9 0.4 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LSM PF01423.22 KDO26164.1 - 1.2e-10 40.9 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SymE_toxin PF08845.10 KDO26164.1 - 0.016 15.2 0.9 0.034 14.2 0.1 1.8 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system DUF4175 PF13779.6 KDO26165.1 - 0.00053 18.0 36.2 0.00062 17.8 36.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) PAT1 PF09770.9 KDO26165.1 - 0.0019 16.6 35.2 0.002 16.5 35.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF4471 PF14740.6 KDO26165.1 - 0.0077 15.5 7.6 0.01 15.1 7.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) V_ATPase_I PF01496.19 KDO26165.1 - 0.0082 14.1 15.3 0.0092 14.0 15.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 KDO26165.1 - 0.35 11.4 24.7 0.55 10.7 24.7 1.4 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 KDO26165.1 - 0.43 9.6 18.8 0.57 9.1 18.8 1.4 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 KDO26165.1 - 0.49 7.5 22.1 0.58 7.2 22.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCSAP PF15748.5 KDO26165.1 - 0.71 10.0 28.5 1.1 9.4 28.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 KDO26165.1 - 0.94 8.2 22.4 1.4 7.6 22.4 1.4 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 KDO26165.1 - 1.3 7.5 30.4 1.9 6.9 30.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF572 PF04502.13 KDO26165.1 - 1.4 8.5 25.9 2.2 7.8 25.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 KDO26165.1 - 2.9 6.7 25.0 4.1 6.3 25.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAGA-Tad1 PF12767.7 KDO26165.1 - 3.2 7.4 25.0 5.2 6.7 25.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit F-protein PF00469.20 KDO26165.1 - 6.9 6.2 17.5 1.5 8.4 14.2 1.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Asp-B-Hydro_N PF05279.11 KDO26165.1 - 7.9 6.5 17.9 11 6.0 17.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SWI-SNF_Ssr4 PF08549.10 KDO26165.1 - 8.3 4.9 32.7 4.2 5.9 28.1 1.9 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF667 PF05018.13 KDO26166.1 - 7e-31 107.4 0.0 2.3e-30 105.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF667) AAA_22 PF13401.6 KDO26168.1 - 3.7e-05 24.0 0.0 0.00016 21.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain FHA PF00498.26 KDO26168.1 - 4e-05 23.9 0.0 0.00011 22.5 0.0 1.7 2 0 0 2 2 2 1 FHA domain AAA_16 PF13191.6 KDO26168.1 - 6.4e-05 23.4 0.3 0.00031 21.2 0.1 2.2 1 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KDO26168.1 - 0.00092 19.2 0.2 0.1 12.5 0.1 3.0 2 1 0 2 2 2 1 NACHT domain CHAT PF12770.7 KDO26168.1 - 0.0013 18.3 0.0 0.0068 15.9 0.0 2.0 1 1 0 1 1 1 1 CHAT domain AAA_30 PF13604.6 KDO26168.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KDO26168.1 - 0.031 14.7 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KDO26168.1 - 0.069 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KDO26168.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea zf-UBR PF02207.20 KDO26170.1 - 1.4e-18 66.8 18.4 1.4e-18 66.8 18.4 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KDO26170.1 - 4e-08 32.9 1.5 5.5e-08 32.5 0.1 2.1 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS RasGEF PF00617.19 KDO26171.1 - 1.6e-30 106.6 0.1 2.7e-30 105.9 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain Ank_5 PF13857.6 KDO26171.1 - 2.5e-19 69.1 4.2 2.3e-06 27.8 0.1 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26171.1 - 1.9e-18 66.8 0.7 2.5e-07 31.2 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26171.1 - 2e-17 63.3 1.5 2.9e-05 24.5 0.0 5.1 3 2 1 5 5 5 3 Ankyrin repeats (many copies) PH PF00169.29 KDO26171.1 - 4.8e-14 52.7 1.0 1e-13 51.7 1.0 1.6 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KDO26171.1 - 1e-12 47.0 2.5 0.038 14.5 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KDO26171.1 - 3.9e-12 46.0 13.9 0.0032 17.9 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat PH_11 PF15413.6 KDO26171.1 - 1.3e-05 25.5 5.4 0.00012 22.5 5.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO26171.1 - 0.00064 19.8 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO26171.1 - 0.0012 19.1 1.1 0.0025 18.0 1.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Choline_transpo PF04515.12 KDO26172.1 - 2e-62 211.3 29.7 2e-62 211.3 29.7 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter TraL PF07178.11 KDO26172.1 - 0.073 13.6 0.1 0.073 13.6 0.1 6.0 4 2 2 6 6 6 0 TraL protein Gly_radical PF01228.21 KDO26174.1 - 0.11 13.1 0.1 0.13 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycine radical CLP1_P PF16575.5 KDO26175.1 - 6e-58 195.8 0.0 8.6e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KDO26175.1 - 5.8e-31 106.6 0.0 1.1e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KDO26175.1 - 1.1e-23 83.9 0.1 1.7e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 KDO26175.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KDO26175.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KDO26175.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KDO26175.1 - 0.034 13.2 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KDO26175.1 - 0.064 13.6 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KDO26175.1 - 0.19 12.2 0.1 0.4 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Mg_trans_NIPA PF05653.14 KDO26176.1 - 1.4e-34 119.6 19.1 1.2e-33 116.5 19.1 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KDO26176.1 - 2.1e-05 24.7 4.4 2.1e-05 24.7 4.4 3.1 2 1 1 3 3 3 2 EamA-like transporter family DMT_6 PF04342.12 KDO26176.1 - 0.035 14.3 0.7 0.035 14.3 0.7 2.8 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) TMEM234 PF10639.9 KDO26176.1 - 0.18 11.8 3.9 0.34 11.0 0.4 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 Aldedh PF00171.22 KDO26177.1 - 6.3e-179 595.3 0.0 7.2e-179 595.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4349 PF14257.6 KDO26178.1 - 5.2e-18 65.3 8.2 4.9e-17 62.1 8.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4349) PIG-Y PF15159.6 KDO26178.1 - 0.16 12.9 2.2 0.58 11.1 0.9 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Biotin_lipoyl PF00364.22 KDO26179.1 - 9.8e-08 31.7 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Aldolase_II PF00596.21 KDO26181.1 - 3.8e-41 141.1 0.3 4.6e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain EF-hand_7 PF13499.6 KDO26182.1 - 1.8e-06 28.3 2.3 0.062 13.8 0.4 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO26182.1 - 0.0028 17.4 0.2 0.033 14.0 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO26182.1 - 0.064 13.2 0.1 0.29 11.2 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain SHE3 PF17078.5 KDO26182.1 - 0.076 12.7 1.5 0.13 11.9 1.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 EF-hand_1 PF00036.32 KDO26182.1 - 0.11 12.1 0.1 0.94 9.2 0.1 2.4 2 0 0 2 2 2 0 EF hand PX PF00787.24 KDO26184.1 - 4.4e-07 29.9 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO26185.1 - 4.1e-06 26.7 0.3 2.1e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 PX domain Zn-ribbon_8 PF09723.10 KDO26185.1 - 0.015 15.4 0.2 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KDO26185.1 - 0.042 13.8 0.1 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PADR1 PF08063.12 KDO26185.1 - 0.19 11.6 0.4 12 5.8 0.1 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain RecR PF02132.15 KDO26185.1 - 0.25 10.9 0.4 0.5 10.0 0.0 1.7 2 0 0 2 2 2 0 RecR protein Tim17 PF02466.19 KDO26186.1 - 0.00013 22.3 0.4 0.0014 19.0 0.2 2.2 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family FYVE PF01363.21 KDO26188.1 - 4.5e-17 62.0 8.5 8.8e-17 61.0 8.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO26188.1 - 0.00042 20.5 3.6 0.00076 19.7 3.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Transposase_24 PF03004.14 KDO26188.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) FYVE PF01363.21 KDO26189.1 - 0.0017 18.4 3.9 0.0028 17.8 3.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-C4_ClpX PF06689.13 KDO26189.1 - 0.0076 16.1 0.5 0.011 15.5 0.5 1.3 1 0 0 1 1 1 1 ClpX C4-type zinc finger zf-RING_5 PF14634.6 KDO26189.1 - 0.031 14.2 4.9 0.27 11.2 4.9 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO26189.1 - 0.59 10.0 5.8 0.62 10.0 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CxC2 PF18803.1 KDO26190.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases LRR_4 PF12799.7 KDO26192.1 - 1.8e-22 79.0 38.3 9.6e-06 25.9 7.2 6.8 5 1 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO26192.1 - 6.6e-22 77.8 15.0 1.6e-12 47.3 3.8 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 KDO26192.1 - 1.9e-17 62.7 42.0 2.4e-07 30.4 3.9 6.2 3 1 4 7 7 7 6 Leucine rich repeat Kelch_6 PF13964.6 KDO26193.1 - 8e-10 38.6 12.6 0.003 17.8 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KDO26193.1 - 8e-07 28.6 2.6 0.03 13.9 0.0 5.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KDO26193.1 - 6.2e-06 26.4 27.6 0.01 16.1 0.3 6.4 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO26193.1 - 1.1e-05 25.3 8.7 1.4 9.0 0.0 5.8 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KDO26193.1 - 8.9e-05 22.4 15.0 0.043 13.8 0.0 6.0 6 1 0 6 6 6 2 Galactose oxidase, central domain EGF_2 PF07974.13 KDO26193.1 - 0.00026 21.3 12.4 0.00085 19.6 12.4 2.0 1 0 0 1 1 1 1 EGF-like domain Kelch_2 PF07646.15 KDO26193.1 - 0.081 12.9 4.1 2 8.6 0.0 4.2 5 0 0 5 5 5 0 Kelch motif EGF PF00008.27 KDO26193.1 - 0.23 11.8 10.5 0.058 13.7 6.6 2.1 2 0 0 2 2 2 0 EGF-like domain LRR_10 PF18805.1 KDO26193.1 - 1.2 8.9 6.0 19 5.0 0.4 3.4 3 0 0 3 3 3 0 Leucine-rich repeat hEGF PF12661.7 KDO26193.1 - 2.8 8.7 11.6 1.6 9.5 7.4 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF PGP_phosphatase PF09419.10 KDO26195.1 - 4.4e-41 140.3 0.0 5.6e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 KDO26195.1 - 1.5e-07 31.9 0.0 0.0016 18.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO26195.1 - 1.3e-06 28.4 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KDO26195.1 - 0.0034 17.5 0.1 0.0067 16.5 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase TLV_coat PF00429.19 KDO26196.1 - 0.0055 15.4 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) bMG3 PF11974.8 KDO26196.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Phage_holin_3_6 PF07332.11 KDO26196.1 - 1.9 8.5 15.8 2.7 8.1 0.0 3.2 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_S3_C PF00189.20 KDO26198.1 - 9.2e-23 80.6 1.0 4.8e-22 78.3 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KDO26198.1 - 1.3e-11 44.1 0.2 2.7e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 KH domain GNAT_acetyltr_2 PF13718.6 KDO26199.1 - 4.2e-97 324.0 0.0 9.6e-97 322.8 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KDO26199.1 - 5e-62 209.7 0.4 5e-62 209.7 0.4 2.1 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KDO26199.1 - 3.3e-60 202.9 0.1 7.7e-60 201.8 0.1 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 KDO26199.1 - 1.3e-33 114.8 0.1 3.3e-33 113.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 KDO26199.1 - 0.0043 17.3 0.0 0.3 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KDO26199.1 - 0.085 13.2 0.5 3.4 8.0 0.2 3.3 2 1 0 2 2 2 0 AAA domain Adeno_PV PF03910.13 KDO26199.1 - 2.7 6.6 8.4 1.8 7.2 6.4 1.7 2 0 0 2 2 2 0 Adenovirus minor core protein PV zf-CW PF07496.15 KDO26200.1 - 0.0019 18.1 0.2 0.0041 17.1 0.2 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger PsbP PF01789.16 KDO26200.1 - 0.086 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 PsbP Peptidase_C21 PF05381.12 KDO26200.1 - 0.11 12.9 0.0 0.69 10.3 0.0 2.2 2 0 0 2 2 2 0 Tymovirus endopeptidase 6PGD PF00393.19 KDO26201.1 - 1.4e-125 418.5 0.0 1.6e-125 418.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KDO26201.1 - 5.8e-45 153.3 0.0 9.2e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KDO26201.1 - 0.0078 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KDO26201.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA PF00004.29 KDO26203.1 - 1e-37 129.5 0.0 1.6e-14 54.5 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KDO26203.1 - 1.1e-14 54.3 3.7 6.2e-05 23.1 0.0 4.0 3 0 0 3 3 3 3 AAA lid domain AAA_22 PF13401.6 KDO26203.1 - 2.2e-12 47.4 5.4 0.1 12.9 0.0 6.4 3 3 1 5 5 5 3 AAA domain AAA_5 PF07728.14 KDO26203.1 - 5e-12 46.0 0.1 0.0067 16.4 0.0 3.8 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO26203.1 - 1.5e-09 37.8 0.4 0.14 11.9 0.2 3.9 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 KDO26203.1 - 5.7e-09 36.6 9.8 0.028 14.8 0.1 4.9 2 2 1 3 3 3 3 AAA ATPase domain Mg_chelatase PF01078.21 KDO26203.1 - 1.1e-08 34.8 1.7 0.017 14.5 0.0 5.0 3 2 2 5 5 5 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KDO26203.1 - 2.7e-08 33.7 0.1 0.02 14.6 0.0 3.8 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KDO26203.1 - 3.9e-08 33.2 0.8 1.2 8.9 0.2 5.5 4 2 0 4 4 4 2 Sigma-54 interaction domain ResIII PF04851.15 KDO26203.1 - 1.7e-07 31.4 0.0 0.00016 21.8 0.0 3.9 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KDO26203.1 - 7.3e-07 29.6 2.2 0.069 13.4 0.0 4.3 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 KDO26203.1 - 2.4e-06 28.1 0.1 0.77 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain Torsin PF06309.11 KDO26203.1 - 2.8e-06 27.4 0.0 0.021 14.9 0.0 3.5 4 0 0 4 4 3 2 Torsin AAA_19 PF13245.6 KDO26203.1 - 3.1e-06 27.6 4.5 0.59 10.5 0.1 5.0 3 2 2 5 5 5 2 AAA domain Viral_helicase1 PF01443.18 KDO26203.1 - 5.2e-06 26.4 0.1 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KDO26203.1 - 1.2e-05 25.5 0.5 0.16 12.1 0.1 3.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KDO26203.1 - 1.7e-05 24.6 0.3 0.92 9.2 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 KDO26203.1 - 2.9e-05 23.7 0.2 0.38 10.2 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region DUF3987 PF13148.6 KDO26203.1 - 4.1e-05 22.8 0.0 0.085 11.9 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) TniB PF05621.11 KDO26203.1 - 5.7e-05 22.6 0.0 0.54 9.6 0.0 4.9 4 2 2 6 6 6 1 Bacterial TniB protein RNA_helicase PF00910.22 KDO26203.1 - 6.1e-05 23.4 0.0 7 7.1 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 KDO26203.1 - 0.00017 21.4 0.0 2.4 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KDO26203.1 - 0.00018 21.7 0.0 0.97 9.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_23 PF13476.6 KDO26203.1 - 0.0007 20.2 0.1 2.1 8.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 KDO26203.1 - 0.00072 20.0 0.3 3.5 8.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain Zot PF05707.12 KDO26203.1 - 0.00074 19.2 0.8 1.7 8.3 0.0 4.6 3 2 0 3 3 3 1 Zonular occludens toxin (Zot) NACHT PF05729.12 KDO26203.1 - 0.0019 18.2 0.1 3.8 7.4 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.27 KDO26203.1 - 0.0026 18.3 0.0 3.9 8.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter PhoH PF02562.16 KDO26203.1 - 0.0046 16.4 1.1 5 6.5 0.0 3.5 3 0 0 3 3 3 0 PhoH-like protein AAA_29 PF13555.6 KDO26203.1 - 0.0093 15.7 0.1 6.1 6.7 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_11 PF13086.6 KDO26203.1 - 0.0096 15.7 0.0 5.5 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KDO26203.1 - 0.01 15.9 3.2 5.2 7.2 0.0 3.5 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 KDO26203.1 - 0.01 15.8 0.1 8.7 6.4 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KDO26203.1 - 0.017 14.0 0.2 4.1 6.2 0.0 3.1 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 KDO26203.1 - 0.022 14.6 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 KDO26203.1 - 0.026 14.3 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.9 KDO26203.1 - 0.032 13.5 5.4 7.8 5.6 0.1 4.2 3 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KDO26203.1 - 0.068 13.1 0.2 7.8 6.4 0.0 3.1 3 0 0 3 3 3 0 NTPase APS_kinase PF01583.20 KDO26203.1 - 0.083 12.8 0.3 18 5.2 0.0 2.9 3 0 0 3 3 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KDO26203.1 - 0.095 12.0 0.1 11 5.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin T2SSE PF00437.20 KDO26203.1 - 0.11 11.5 0.0 6.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.22 KDO26203.1 - 0.12 12.0 0.7 19 4.8 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KDO26203.1 - 0.17 11.0 0.0 16 4.6 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain UvrD-helicase PF00580.21 KDO26203.1 - 0.2 11.1 0.0 6.8 6.1 0.0 2.6 3 0 0 3 3 2 0 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KDO26203.1 - 0.24 10.7 0.1 21 4.4 0.0 3.2 3 0 0 3 3 3 0 KaiC AAA PF00004.29 KDO26205.1 - 4.6e-07 30.3 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO26205.1 - 7.9e-06 26.4 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KDO26205.1 - 2e-05 24.6 0.1 0.097 12.6 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_7 PF12775.7 KDO26205.1 - 2.9e-05 23.7 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KDO26205.1 - 0.0003 20.8 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO26205.1 - 0.00034 20.4 0.4 0.48 10.2 0.0 3.2 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KDO26205.1 - 0.0012 19.2 0.1 0.0047 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 KDO26205.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain T2SSE PF00437.20 KDO26205.1 - 0.0014 17.7 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 KDO26205.1 - 0.0024 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 KDO26205.1 - 0.0025 18.3 0.0 0.0055 17.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KDO26205.1 - 0.0035 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO26205.1 - 0.0045 16.7 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO26205.1 - 0.0052 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KDO26205.1 - 0.0061 16.0 0.2 0.073 12.5 0.2 2.2 1 1 0 1 1 1 1 Bacterial TniB protein AAA_25 PF13481.6 KDO26205.1 - 0.0072 15.9 0.1 0.13 11.9 0.0 2.9 3 1 1 4 4 4 1 AAA domain NACHT PF05729.12 KDO26205.1 - 0.0094 15.9 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KDO26205.1 - 0.0097 16.3 0.0 0.029 14.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KDO26205.1 - 0.012 15.3 0.3 0.047 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KDO26205.1 - 0.017 14.9 0.0 0.078 12.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KDO26205.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KDO26205.1 - 0.027 13.7 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 KDO26205.1 - 0.03 14.1 0.1 0.099 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KDO26205.1 - 0.037 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Mg_chelatase PF01078.21 KDO26205.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KDO26205.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KDO26205.1 - 0.06 13.0 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KDO26205.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO26205.1 - 0.068 13.5 0.1 0.18 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KDO26205.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO26205.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 KDO26205.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CbiA PF01656.23 KDO26205.1 - 0.098 12.7 0.1 0.46 10.5 0.1 2.2 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 KDO26205.1 - 0.1 11.9 0.2 1.1 8.5 0.0 2.2 1 1 1 2 2 2 0 KaiC DUF815 PF05673.13 KDO26205.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Glutaredoxin PF00462.24 KDO26206.1 - 4.6e-18 65.2 0.1 7.5e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KDO26206.1 - 0.00012 22.4 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KDO26206.1 - 0.00077 19.3 0.7 0.013 15.3 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain GST_N_3 PF13417.6 KDO26206.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO26206.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 KDO26206.1 - 0.013 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KDO26206.1 - 0.04 14.4 0.1 0.057 13.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KDO26206.1 - 0.081 13.0 0.1 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin domain Ras PF00071.22 KDO26207.1 - 7.7e-66 220.7 0.4 1e-65 220.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO26207.1 - 4.7e-36 123.6 0.8 7.3e-36 123.0 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO26207.1 - 5.3e-16 58.6 0.1 6.9e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO26207.1 - 2.7e-06 27.1 0.4 6.7e-06 25.8 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO26207.1 - 1.3e-05 24.7 0.1 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO26207.1 - 2.3e-05 24.5 0.1 3.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO26207.1 - 0.00011 22.1 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KDO26207.1 - 0.00057 19.4 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KDO26207.1 - 0.0026 17.5 0.1 0.041 13.6 0.1 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KDO26207.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KDO26207.1 - 0.038 13.7 0.3 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO26207.1 - 0.095 13.1 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 KDO26207.1 - 0.099 11.7 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 KDO26207.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KDO26207.1 - 0.16 12.3 0.1 0.24 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.21 KDO26208.1 - 1.2e-105 354.2 0.0 6.1e-105 351.9 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 KDO26208.1 - 1.4e-12 48.1 0.0 4.6e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 MyTH4 domain AAA_16 PF13191.6 KDO26208.1 - 6.2e-06 26.7 0.8 7.9e-05 23.1 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain SH3_9 PF14604.6 KDO26208.1 - 9.6e-05 22.2 0.1 0.00023 21.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_30 PF13604.6 KDO26208.1 - 0.0036 17.0 0.6 0.0099 15.6 0.6 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KDO26208.1 - 0.0052 16.8 0.6 0.011 15.8 0.6 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KDO26208.1 - 0.0072 16.6 0.1 0.027 14.7 0.1 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KDO26208.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 KDO26208.1 - 0.016 14.4 0.2 0.024 13.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KDO26208.1 - 0.021 14.4 0.2 0.1 12.1 0.2 2.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO26208.1 - 0.036 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KDO26208.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SH3_2 PF07653.17 KDO26208.1 - 0.073 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain IQ PF00612.27 KDO26208.1 - 0.12 12.2 2.4 0.46 10.4 2.4 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif RsgA_GTPase PF03193.16 KDO26208.1 - 0.21 11.5 0.1 0.39 10.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase GYF_2 PF14237.6 KDO26209.1 - 7.8e-15 54.4 0.1 8.9e-15 54.2 0.1 1.1 1 0 0 1 1 1 1 GYF domain 2 GYF PF02213.16 KDO26209.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 GYF domain HlyIII PF03006.20 KDO26210.1 - 8.1e-55 186.0 21.8 1.6e-49 168.6 14.5 2.1 2 0 0 2 2 2 2 Haemolysin-III related B12D PF06522.11 KDO26210.1 - 0.024 14.4 7.0 0.099 12.5 0.8 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Pox_I5 PF04713.12 KDO26210.1 - 0.056 13.5 0.7 0.16 12.0 0.7 1.7 1 0 0 1 1 1 0 Poxvirus protein I5 DUF962 PF06127.11 KDO26210.1 - 0.51 10.4 10.1 0.39 10.8 0.5 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Myb_DNA-bind_4 PF13837.6 KDO26211.1 - 0.00093 19.5 0.0 0.0043 17.4 0.0 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain FKBP_N PF01346.18 KDO26211.1 - 9.2 7.3 10.2 3 8.9 4.8 2.4 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TMEM70 PF06979.12 KDO26212.1 - 3e-33 115.0 0.1 3.7e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Ephrin_rec_like PF07699.13 KDO26213.1 - 6.2e-30 102.7 74.1 9.1e-06 25.3 3.6 10.7 3 2 8 11 11 11 11 Putative ephrin-receptor like LRR_8 PF13855.6 KDO26213.1 - 4.2e-14 52.0 8.6 1.2e-07 31.4 0.1 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO26213.1 - 1.8e-13 50.4 9.3 0.025 15.0 0.0 4.7 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO26213.1 - 1.4e-06 27.9 0.1 0.94 9.7 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat NCD3G PF07562.14 KDO26213.1 - 3.6e-06 26.8 50.8 0.23 11.4 0.8 9.5 4 3 0 9 9 9 7 Nine Cysteines Domain of family 3 GPCR LRR_1 PF00560.33 KDO26213.1 - 4.4e-06 26.5 7.6 46 5.1 0.0 7.9 8 0 0 8 8 8 0 Leucine Rich Repeat TNFR_c6 PF00020.18 KDO26213.1 - 0.0055 17.1 51.3 0.92 10.0 0.8 10.5 8 3 1 9 9 9 6 TNFR/NGFR cysteine-rich region FOP_dimer PF09398.10 KDO26214.1 - 0.00086 19.5 0.1 0.0029 17.8 0.0 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain Ras PF00071.22 KDO26215.1 - 1.3e-35 122.4 0.3 1.6e-35 122.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO26215.1 - 3.9e-26 91.6 0.1 6.1e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO26215.1 - 6.3e-09 35.5 0.1 7.4e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO26215.1 - 7.3e-06 25.5 0.4 9.1e-06 25.2 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KDO26215.1 - 0.00014 20.8 0.6 0.0056 15.6 0.0 2.0 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 KDO26215.1 - 0.00023 20.8 0.3 0.0017 18.0 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO26215.1 - 0.0018 17.7 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO26215.1 - 0.03 14.4 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Chorismate_bind PF00425.18 KDO26215.1 - 0.086 12.4 0.1 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 chorismate binding enzyme Phage_T4_gp19 PF06841.12 KDO26215.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 G-alpha PF00503.20 KDO26215.1 - 0.2 10.8 1.6 0.69 9.0 0.1 2.3 1 1 2 3 3 3 0 G-protein alpha subunit HA2 PF04408.23 KDO26216.1 - 1.6e-22 79.8 0.6 6e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KDO26216.1 - 4.7e-22 78.2 0.0 9.6e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KDO26216.1 - 3.8e-14 53.0 0.0 2.2e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.23 KDO26216.1 - 3.4e-10 40.1 1.5 9e-10 38.8 1.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KDO26216.1 - 5e-07 30.1 0.1 1.3e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KDO26216.1 - 8.8e-06 25.6 1.1 0.00015 21.6 1.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KDO26216.1 - 0.00063 20.1 0.3 0.0015 18.9 0.3 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO26216.1 - 0.0022 17.1 0.1 0.008 15.3 0.1 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KDO26216.1 - 0.0028 17.4 0.2 0.006 16.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KDO26216.1 - 0.0058 17.2 0.6 1.7 9.2 0.1 3.0 2 1 1 3 3 3 1 ABC transporter AAA_14 PF13173.6 KDO26216.1 - 0.0091 16.0 0.1 0.041 13.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KDO26216.1 - 0.02 14.6 0.2 0.044 13.4 0.1 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 KDO26216.1 - 0.023 14.1 0.2 0.066 12.7 0.2 1.7 1 0 0 1 1 1 0 PhoH-like protein Microtub_bd PF16796.5 KDO26216.1 - 0.035 14.0 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding IstB_IS21 PF01695.17 KDO26216.1 - 0.086 12.6 0.0 17 5.1 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KDO26216.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KDO26216.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KDO26216.1 - 0.14 12.2 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 KDO26216.1 - 0.15 12.5 0.7 6.1 7.3 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3915 PF13054.6 KDO26216.1 - 1.7 8.7 3.8 5 7.1 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Apis_Csd PF11671.8 KDO26216.1 - 5.5 7.0 15.0 6.4 6.8 12.2 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein Fe-S_biosyn PF01521.20 KDO26217.1 - 5.1e-17 62.1 0.0 5.8e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SpoIIE PF07228.12 KDO26218.1 - 8.8e-12 45.3 0.1 3.6e-11 43.3 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KDO26218.1 - 0.00023 20.9 0.0 0.00052 19.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KDO26218.1 - 0.00067 19.4 0.2 0.37 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C TMEM70 PF06979.12 KDO26219.1 - 1.2e-09 38.6 0.2 2.5e-09 37.6 0.2 1.4 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex CorA PF01544.18 KDO26219.1 - 1.1e-08 34.7 13.9 2e-07 30.6 13.9 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AP1AR PF15745.5 KDO26220.1 - 0.22 11.1 7.1 0.32 10.6 7.1 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF4407 PF14362.6 KDO26220.1 - 4.4 6.6 13.3 7.4 5.8 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TRP PF06011.12 KDO26221.1 - 0.00018 20.4 10.1 0.00018 20.4 10.1 3.3 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel DUF1422 PF07226.11 KDO26221.1 - 0.037 14.0 9.5 1.2 9.2 10.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) DUF4059 PF13268.6 KDO26221.1 - 5.9 7.4 10.9 0.93 9.9 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4059) IBR PF01485.21 KDO26222.1 - 0.081 13.2 0.8 0.081 13.2 0.8 4.1 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain TRI12 PF06609.13 KDO26223.1 - 0.027 12.9 0.0 0.043 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pkinase_Tyr PF07714.17 KDO26224.1 - 1.4e-45 155.6 0.0 1.7e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26224.1 - 6.7e-45 153.5 0.0 8.1e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26225.1 - 5.5e-31 107.8 0.0 8.5e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26225.1 - 1.1e-24 87.2 0.0 1.7e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glycophorin_A PF01102.18 KDO26225.1 - 0.0024 18.1 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 KDO26225.1 - 0.014 15.3 0.9 0.029 14.3 0.9 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5518 PF17647.1 KDO26225.1 - 0.016 15.3 0.2 0.039 14.1 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Adeno_E3_CR2 PF02439.15 KDO26225.1 - 0.017 14.9 0.6 0.035 13.9 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM52 PF14979.6 KDO26226.1 - 0.095 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 CBP_BcsF PF11120.8 KDO26226.1 - 5.1 7.3 6.7 4.8 7.4 0.7 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Pkinase_Tyr PF07714.17 KDO26227.1 - 6.5e-54 182.9 0.0 8.4e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26227.1 - 1.1e-47 162.7 0.0 1.7e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO26227.1 - 0.0028 17.6 0.1 0.0067 16.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO26227.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Podoplanin PF05808.11 KDO26227.1 - 0.13 12.3 0.3 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Podoplanin Pkinase PF00069.25 KDO26228.1 - 1e-66 225.0 0.0 2.6e-66 223.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26228.1 - 1.4e-30 106.5 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO26228.1 - 1.4e-06 27.4 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO26228.1 - 0.0019 17.6 0.0 0.0056 16.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 KDO26228.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KDO26228.1 - 0.048 13.6 0.1 0.28 11.1 0.3 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO26228.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KDO26228.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KDO26228.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 KDO26229.1 - 3.9e-18 65.8 0.1 2.3e-07 31.3 0.0 3.8 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26229.1 - 3.6e-16 59.3 0.2 1.9e-07 31.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO26229.1 - 5.2e-14 52.1 2.2 8.8e-06 25.9 0.1 4.1 3 2 1 4 4 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26229.1 - 7.5e-14 50.5 0.2 0.004 17.5 0.2 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO26229.1 - 3.2e-11 43.1 1.3 0.046 14.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat FYVE PF01363.21 KDO26229.1 - 1e-05 25.6 10.5 2.3e-05 24.4 10.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Cytochrom_c3_2 PF14537.6 KDO26229.1 - 0.0043 17.5 2.5 0.01 16.3 0.9 2.3 2 0 0 2 2 2 1 Cytochrome c3 Cytochrom_CIII PF02085.16 KDO26229.1 - 0.0068 16.7 2.3 0.018 15.4 2.3 1.7 1 0 0 1 1 1 1 Class III cytochrome C family FAM91_C PF14648.6 KDO26229.1 - 0.076 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus PSCyt3 PF07627.11 KDO26229.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1588) Cytochrome_C7 PF14522.6 KDO26229.1 - 1.6 8.8 9.8 0.28 11.2 5.1 2.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 KDO26229.1 - 2.8 7.8 10.2 1.3 8.8 0.4 3.0 2 1 1 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Spc7 PF08317.11 KDO26229.1 - 3.9 6.2 11.7 0.29 10.0 4.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Ribosomal_L14 PF00238.19 KDO26230.1 - 7e-34 116.5 0.0 8.4e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Methyltransf_25 PF13649.6 KDO26231.1 - 5.5e-06 27.0 0.0 9.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO26231.1 - 7.2e-05 22.7 0.0 0.00057 19.8 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 KDO26231.1 - 0.00033 20.2 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 2 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KDO26231.1 - 0.015 15.9 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SO_alpha_A3 PF17806.1 KDO26231.1 - 0.049 14.0 0.2 7.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain CMAS PF02353.20 KDO26231.1 - 0.19 11.0 0.2 0.44 9.8 0.1 1.5 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KDO26231.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Queuosine_synth PF02547.15 KDO26231.1 - 0.23 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein DUF3450 PF11932.8 KDO26232.1 - 9.1e-05 21.9 30.9 0.0026 17.1 1.6 3.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3450) GIT_CC PF16559.5 KDO26232.1 - 0.00016 21.4 3.9 0.26 11.2 0.0 3.3 3 0 0 3 3 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor Fez1 PF06818.15 KDO26232.1 - 0.0019 18.7 27.9 0.067 13.6 7.2 2.6 2 1 0 2 2 2 2 Fez1 Prominin PF05478.11 KDO26232.1 - 0.0022 16.1 12.0 0.15 9.9 6.1 2.1 2 0 0 2 2 2 2 Prominin TPR_MLP1_2 PF07926.12 KDO26232.1 - 0.0026 17.8 8.5 0.0026 17.8 8.5 4.2 2 2 2 4 4 4 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KDO26232.1 - 0.012 15.6 27.3 0.21 11.6 5.3 3.9 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KDO26232.1 - 0.02 15.1 42.4 0.075 13.3 16.8 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HEPN_Toprim_N PF18871.1 KDO26232.1 - 0.02 14.8 2.4 0.027 14.4 1.6 1.7 1 1 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 PLAC9 PF15205.6 KDO26232.1 - 0.021 15.2 1.1 2.5 8.6 0.3 3.3 3 0 0 3 3 3 0 Placenta-specific protein 9 EspB_PE PF18625.1 KDO26232.1 - 0.023 15.2 0.3 0.023 15.2 0.3 3.1 3 1 1 4 4 3 0 ESX-1 secreted protein B PE domain DUF3150 PF11348.8 KDO26232.1 - 0.035 13.3 9.9 0.018 14.3 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3150) DUF5082 PF16888.5 KDO26232.1 - 0.048 13.9 17.1 0.16 12.2 6.3 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Laminin_II PF06009.12 KDO26232.1 - 0.053 13.5 18.5 1.4 9.0 0.4 4.4 2 2 2 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 KDO26232.1 - 0.07 13.2 18.3 0.24 11.5 0.3 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KDO26232.1 - 0.14 12.2 15.8 3.5 7.7 6.6 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 KDO26232.1 - 0.17 11.4 30.8 2.7 7.5 5.6 3.0 1 1 1 2 2 2 0 Intermediate filament protein MPS2 PF17060.5 KDO26232.1 - 0.23 10.7 7.1 0.052 12.8 2.6 1.9 2 1 0 2 2 2 0 Monopolar spindle protein 2 APG6_N PF17675.1 KDO26232.1 - 0.28 11.7 36.4 0.05 14.1 6.2 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KDO26232.1 - 0.3 11.5 6.5 14 6.2 0.0 4.2 3 1 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 KDO26232.1 - 0.32 11.3 13.3 5.4 7.4 0.4 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KDO26232.1 - 0.38 11.3 18.8 1.5 9.4 1.6 5.2 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 KDO26232.1 - 0.48 8.5 26.1 0.004 15.4 14.3 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Prefoldin PF02996.17 KDO26232.1 - 0.59 10.0 0.0 0.59 10.0 0.0 4.7 5 0 0 5 5 5 0 Prefoldin subunit DUF16 PF01519.16 KDO26232.1 - 0.6 10.6 17.9 0.087 13.3 1.2 3.5 1 1 1 3 3 3 0 Protein of unknown function DUF16 Mod_r PF07200.13 KDO26232.1 - 0.63 10.1 29.2 0.15 12.2 5.2 3.6 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Vps51 PF08700.11 KDO26232.1 - 0.82 9.8 9.7 9 6.5 0.9 4.2 3 2 0 3 3 3 0 Vps51/Vps67 ZapB PF06005.12 KDO26232.1 - 1.4 9.5 27.2 0.2 12.1 3.2 4.2 3 1 1 4 4 3 0 Cell division protein ZapB TTRAP PF14203.6 KDO26232.1 - 1.6 8.7 7.4 4.3 7.4 0.1 3.7 4 2 0 4 4 3 0 Putative tranposon-transfer assisting protein Perilipin PF03036.16 KDO26232.1 - 2.4 7.1 17.9 0.28 10.2 12.5 1.8 2 0 0 2 2 2 0 Perilipin family CALCOCO1 PF07888.11 KDO26232.1 - 2.7 6.8 33.3 0.55 9.0 15.7 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GP20 PF06810.11 KDO26232.1 - 2.7 7.8 21.2 1.6 8.5 3.6 3.7 1 1 3 4 4 4 0 Phage minor structural protein GP20 Jnk-SapK_ap_N PF09744.9 KDO26232.1 - 3.2 8.0 34.9 3.3 7.9 8.6 3.6 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 ERM PF00769.19 KDO26232.1 - 3.3 7.5 33.6 0.81 9.5 15.5 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family RasGAP_C PF03836.15 KDO26232.1 - 3.9 7.6 12.6 1 9.5 3.4 3.3 1 1 0 2 2 2 0 RasGAP C-terminus Uso1_p115_C PF04871.13 KDO26232.1 - 4.4 7.7 29.6 2.2 8.7 12.0 3.5 2 2 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 KDO26232.1 - 4.5 7.3 35.6 2.9 8.0 9.8 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 KDO26232.1 - 5.6 7.0 19.5 8 6.5 0.2 5.3 5 2 0 5 5 4 0 Prefoldin subunit DUF4407 PF14362.6 KDO26232.1 - 6.4 6.0 32.9 10 5.4 11.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 KDO26232.1 - 6.5 7.1 16.4 7.8 6.8 0.0 5.8 7 2 0 7 7 5 0 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 KDO26232.1 - 6.7 6.2 26.9 1.5 8.4 2.3 3.1 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 COG2 PF06148.11 KDO26232.1 - 6.8 6.8 17.2 6.1 6.9 1.4 4.1 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1192 PF06698.11 KDO26232.1 - 7.9 6.6 9.2 0.53 10.4 0.3 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) MAD PF05557.13 KDO26232.1 - 8.8 4.6 30.8 1.2 7.4 13.1 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein TraV PF09676.10 KDO26233.1 - 0.93 10.5 5.8 0.83 10.6 1.9 2.3 1 1 1 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) DUF3365 PF11845.8 KDO26237.1 - 0.0059 16.9 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3365) Mucin PF01456.17 KDO26237.1 - 2.5 8.1 23.3 0.66 10.0 2.3 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Sigma_M_inh PF17453.2 KDO26238.1 - 0.089 13.2 1.6 0.54 10.7 0.2 2.9 2 0 0 2 2 2 0 Sigma-M inhibitor Uroplakin_II PF07353.12 KDO26238.1 - 3.8 7.0 12.2 1.4 8.4 2.7 3.1 3 0 0 3 3 3 0 Uroplakin II Ion_trans PF00520.31 KDO26239.1 - 3.6e-29 101.7 17.3 6e-29 101.0 17.3 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO26239.1 - 1.4e-10 41.1 0.1 3e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO26239.1 - 5.3e-10 39.1 7.2 5.3e-10 39.1 7.2 2.0 2 1 0 2 2 2 1 Ion channel GerPC PF10737.9 KDO26239.1 - 0.066 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC Pyrophosphatase PF00719.19 KDO26239.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Inorganic pyrophosphatase KfrA_N PF11740.8 KDO26239.1 - 0.71 10.6 2.8 0.41 11.3 0.3 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term ECH_1 PF00378.20 KDO26240.1 - 6.7e-45 153.4 0.0 1.3e-44 152.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO26240.1 - 5.5e-23 82.0 0.3 5.2e-20 72.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SAPI PF16560.5 KDO26240.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative mobile pathogenicity island Asp PF00026.23 KDO26241.1 - 0.0018 17.8 0.0 0.0051 16.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Ank_4 PF13637.6 KDO26242.1 - 1.8e-30 104.9 12.0 1.3e-10 41.6 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26242.1 - 3.2e-30 104.5 0.6 4.2e-16 59.3 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO26242.1 - 6.5e-24 81.4 5.3 1.2e-06 28.4 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO26242.1 - 4.7e-21 74.3 7.5 5.4e-05 23.4 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO26242.1 - 2.5e-16 59.5 5.8 4e-06 27.0 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF2808 PF10989.8 KDO26242.1 - 0.0065 16.5 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2808) Lipase_3 PF01764.25 KDO26243.1 - 0.0097 15.8 0.1 0.0097 15.8 0.1 1.8 1 1 1 2 2 2 1 Lipase (class 3) Maf PF02545.14 KDO26244.1 - 0.021 14.7 2.9 0.063 13.1 0.4 2.2 2 0 0 2 2 2 0 Maf-like protein GerPC PF10737.9 KDO26244.1 - 0.047 13.8 1.6 0.12 12.4 1.6 1.7 1 0 0 1 1 1 0 Spore germination protein GerPC hnRNP_Q_AcD PF18360.1 KDO26245.1 - 3.5e-12 46.1 0.1 6.5e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_1 PF00076.22 KDO26245.1 - 1.2e-11 44.3 0.0 3.3e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HR1 PF02185.16 KDO26246.1 - 0.011 15.8 3.7 0.011 15.8 3.7 1.9 2 0 0 2 2 2 0 Hr1 repeat DUF4140 PF13600.6 KDO26246.1 - 0.069 13.6 4.7 0.15 12.5 4.7 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TrbI_Ftype PF09677.10 KDO26246.1 - 0.94 9.8 5.0 0.32 11.4 2.0 1.7 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) ELO PF01151.18 KDO26247.1 - 5.5e-52 176.8 32.2 6.6e-52 176.5 32.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SNAPc_SNAP43 PF09808.9 KDO26248.1 - 2.7e-07 30.7 0.0 4.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Rnk_N PF14760.6 KDO26250.1 - 0.00052 20.4 13.8 5.5 7.6 0.2 6.4 6 0 0 6 6 6 4 Rnk N-terminus TPR_12 PF13424.6 KDO26251.1 - 2.8e-14 53.2 2.4 6.1e-09 36.1 0.8 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat PH PF00169.29 KDO26251.1 - 3.4e-12 46.8 0.0 7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 PH domain TPR_7 PF13176.6 KDO26251.1 - 1.8e-06 27.6 0.6 0.0057 16.6 0.0 4.3 3 1 0 4 4 4 1 Tetratricopeptide repeat PH_8 PF15409.6 KDO26251.1 - 2.5e-06 27.7 0.3 2.2e-05 24.7 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO26251.1 - 1.1e-05 25.7 0.6 0.00012 22.4 0.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain TPR_10 PF13374.6 KDO26251.1 - 0.0099 15.7 1.6 0.93 9.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO26251.1 - 0.01 16.4 2.6 29 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26251.1 - 0.06 13.5 1.4 16 5.9 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26251.1 - 0.075 12.9 0.1 3.1 7.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Gemini_BL1 PF00845.19 KDO26251.1 - 0.15 11.6 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Geminivirus BL1 movement protein EF-hand_6 PF13405.6 KDO26253.1 - 0.0045 16.8 0.1 0.16 12.0 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KDO26253.1 - 0.056 13.0 0.1 0.98 9.0 0.0 2.7 3 0 0 3 3 3 0 EF hand Dockerin_1 PF00404.18 KDO26253.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_1 PF00036.32 KDO26253.1 - 0.11 12.1 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF1456 PF07308.13 KDO26254.1 - 0.046 14.1 0.1 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF3944 PF13099.6 KDO26254.1 - 0.084 12.7 0.2 0.67 9.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3944) PseudoU_synth_2 PF00849.22 KDO26255.1 - 3.7e-30 105.1 0.0 6.9e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KDO26255.1 - 0.009 15.7 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 S4 domain NINJA_B PF16136.5 KDO26255.1 - 0.28 11.6 2.8 0.62 10.5 2.1 1.9 2 0 0 2 2 2 0 Putative nuclear localisation signal Motile_Sperm PF00635.26 KDO26256.1 - 3.2e-20 72.0 0.1 2.7e-14 52.9 0.1 3.5 3 0 0 3 3 3 3 MSP (Major sperm protein) domain DnaJ PF00226.31 KDO26257.1 - 2.8e-30 104.2 3.7 2.8e-30 104.2 3.7 1.8 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 KDO26257.1 - 0.18 11.7 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein TMP_2 PF06791.13 KDO26257.1 - 0.49 10.0 2.4 1 9.0 2.4 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein START PF01852.19 KDO26258.1 - 7.5e-26 90.8 0.1 9.4e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 START domain Motile_Sperm PF00635.26 KDO26259.1 - 2.3e-20 72.4 0.8 9.7e-10 38.3 0.0 2.8 3 0 0 3 3 3 2 MSP (Major sperm protein) domain Motile_Sperm PF00635.26 KDO26260.1 - 3.5e-11 42.9 0.0 2.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 KDO26260.1 - 0.03 14.5 0.0 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KDO26261.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Smg4_UPF3 PF03467.15 KDO26262.1 - 1.3e-17 64.3 0.0 1.6e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family Cation_ATPase_N PF00690.26 KDO26262.1 - 0.17 11.6 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Hemerythrin PF01814.23 KDO26263.1 - 2.3e-06 28.2 2.8 1.1e-05 26.0 2.8 1.9 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain RHH_1 PF01402.21 KDO26263.1 - 0.055 13.4 0.1 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF4806 PF16064.5 KDO26263.1 - 0.11 12.8 0.0 0.95 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) LEM PF03020.15 KDO26263.1 - 0.19 11.3 0.1 0.52 9.9 0.0 1.8 2 0 0 2 2 2 0 LEM domain LRR_4 PF12799.7 KDO26264.1 - 6e-19 67.8 20.7 1.2e-05 25.6 1.4 5.2 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO26264.1 - 3.5e-16 59.2 6.3 2.4e-07 30.4 0.7 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KDO26264.1 - 1.5e-15 56.7 15.0 1.4e-08 34.4 1.3 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KDO26264.1 - 0.002 18.4 16.8 7.9 7.5 0.1 7.5 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO26264.1 - 0.54 10.4 28.8 22 5.4 0.0 7.7 8 0 0 8 8 8 0 Leucine Rich repeat Semialdhyde_dhC PF02774.18 KDO26265.1 - 6.3e-50 169.8 0.0 8.9e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KDO26265.1 - 1.9e-27 96.1 0.8 3.7e-27 95.2 0.4 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KDO26265.1 - 0.0013 18.4 0.1 0.0082 15.8 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 KDO26265.1 - 0.0024 18.4 0.5 0.0046 17.5 0.5 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.16 KDO26265.1 - 0.018 15.8 0.6 0.16 12.6 0.1 2.3 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KDO26265.1 - 0.13 12.4 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2070 PF09843.9 KDO26266.1 - 3.8 5.7 8.9 6.6 4.9 8.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Syntaxin_2 PF14523.6 KDO26267.1 - 2.5e-10 40.6 8.9 5e-09 36.5 3.4 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 KDO26267.1 - 0.00088 19.2 0.1 0.00088 19.2 0.1 2.3 3 1 1 4 4 4 1 SNARE domain FAA_hydrolase_N PF09298.11 KDO26267.1 - 0.0042 17.2 1.2 0.0093 16.1 0.8 1.8 1 1 0 1 1 1 1 Fumarylacetoacetase N-terminal PhageMin_Tail PF10145.9 KDO26267.1 - 0.022 14.6 4.2 0.036 13.9 4.2 1.8 1 1 0 1 1 1 0 Phage-related minor tail protein ING PF12998.7 KDO26267.1 - 0.026 15.1 4.2 0.49 11.0 0.3 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding YusW PF14039.6 KDO26267.1 - 0.088 13.3 0.3 0.088 13.3 0.3 2.7 2 2 2 4 4 4 0 YusW-like protein Syntaxin PF00804.25 KDO26267.1 - 0.11 12.1 9.0 2.2 7.9 9.0 2.3 1 1 0 1 1 1 0 Syntaxin TACC_C PF05010.14 KDO26267.1 - 0.14 11.9 8.1 0.19 11.5 1.1 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sec8_exocyst PF04048.14 KDO26267.1 - 0.28 11.1 6.6 0.48 10.3 3.3 2.5 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF948 PF06103.11 KDO26267.1 - 2.1 8.7 7.0 9.5 6.6 1.3 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 KDO26267.1 - 2.3 9.0 7.0 8.6 7.1 0.9 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 KDO26267.1 - 9 5.4 7.3 4.2 6.5 1.9 2.0 1 1 2 3 3 3 0 TMPIT-like protein SWIRM-assoc_2 PF16496.5 KDO26268.1 - 0.057 12.3 0.1 0.094 11.6 0.1 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pkinase PF00069.25 KDO26270.1 - 3.2e-60 203.7 0.0 4.8e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26270.1 - 9.5e-28 97.2 0.0 1.5e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO26270.1 - 2.5e-09 36.9 0.1 1.5e-06 27.7 0.0 3.3 3 0 0 3 3 3 1 Kinase-like PH PF00169.29 KDO26270.1 - 5.9e-09 36.4 0.1 1.3e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.23 KDO26270.1 - 0.00043 20.3 0.7 0.0025 17.8 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH_11 PF15413.6 KDO26270.1 - 0.0048 17.3 1.2 0.0048 17.3 1.2 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain Tegument_dsDNA PF12818.7 KDO26270.1 - 0.037 13.2 0.1 0.083 12.0 0.1 1.6 2 0 0 2 2 2 0 dsDNA viral tegument protein FTA2 PF13095.6 KDO26270.1 - 0.04 13.5 0.1 9.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO26270.1 - 0.049 12.6 0.2 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO26270.1 - 0.079 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 F-box-like PF12937.7 KDO26271.1 - 2.1e-06 27.5 0.8 4.1e-06 26.6 0.8 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO26271.1 - 6e-06 26.0 0.4 1.2e-05 25.0 0.4 1.4 1 0 0 1 1 1 1 F-box domain SPRY PF00622.28 KDO26271.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 SPRY domain Myb_DNA-binding PF00249.31 KDO26272.1 - 5e-07 29.8 1.8 0.00026 21.1 0.1 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO26272.1 - 9.2e-06 25.8 0.0 8.1e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain MCLC PF05934.11 KDO26273.1 - 1.3 7.6 4.9 1.6 7.4 4.9 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Asp_Glu_race PF01177.22 KDO26275.1 - 8e-22 78.2 0.1 1.1e-21 77.8 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase XdhC_C PF13478.6 KDO26275.1 - 0.021 15.3 0.5 0.043 14.3 0.2 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Myosin_head PF00063.21 KDO26276.1 - 2.7e-158 528.2 0.0 4.1e-158 527.6 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 KDO26276.1 - 1.3e-11 44.5 18.0 3.6e-11 43.0 18.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 KDO26276.1 - 0.017 14.9 1.2 0.017 14.9 1.2 4.8 4 0 0 4 4 4 0 IQ calmodulin-binding motif Spc29 PF17082.5 KDO26276.1 - 0.028 14.2 0.2 1 9.2 0.1 2.6 2 0 0 2 2 2 0 Spindle Pole Component 29 COMM_domain PF07258.14 KDO26276.1 - 0.055 13.6 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 COMM domain TYA PF01021.19 KDO26276.1 - 0.94 9.8 3.4 2.7 8.4 0.4 2.6 2 0 0 2 2 2 0 TYA transposon protein Myosin_head PF00063.21 KDO26278.1 - 4.7e-126 421.7 0.0 7.7e-99 331.8 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 KDO26278.1 - 0.014 15.7 0.1 0.065 13.5 0.1 2.2 1 0 0 1 1 1 0 AAA domain SH3_19 PF18597.1 KDO26278.1 - 0.017 14.9 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain IQ PF00612.27 KDO26278.1 - 0.06 13.2 20.3 0.068 13.0 1.1 4.4 4 0 0 4 4 4 0 IQ calmodulin-binding motif Myosin_N PF02736.19 KDO26278.1 - 0.16 11.8 0.3 0.46 10.4 0.3 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain TsaE PF02367.17 KDO26278.1 - 0.17 11.9 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NAD_binding_8 PF13450.6 KDO26279.1 - 5e-11 42.7 1.9 4e-10 39.8 0.1 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KDO26279.1 - 5.9e-09 36.0 7.8 1.3e-05 25.0 1.6 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KDO26279.1 - 1.5e-08 34.5 0.2 6.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KDO26279.1 - 6.1e-08 32.4 0.3 0.003 16.9 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KDO26279.1 - 1.8e-07 30.6 4.5 8.7e-06 25.1 2.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KDO26279.1 - 1.1e-06 28.2 0.0 0.00028 20.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO26279.1 - 2.3e-06 28.1 1.0 0.0057 17.2 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO26279.1 - 9.5e-06 25.0 1.5 8e-05 22.0 0.2 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KDO26279.1 - 2.1e-05 23.4 0.9 0.0017 17.1 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 KDO26279.1 - 4e-05 23.0 0.1 6.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KDO26279.1 - 4.6e-05 22.5 1.1 0.013 14.4 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KDO26279.1 - 0.078 12.2 0.9 0.14 11.3 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KDO26279.1 - 0.093 11.5 0.4 0.19 10.5 0.1 1.6 2 0 0 2 2 2 0 MCRA family GIDA PF01134.22 KDO26279.1 - 0.26 10.3 9.8 0.02 14.0 1.7 2.6 3 1 0 3 3 3 0 Glucose inhibited division protein A SPRY PF00622.28 KDO26280.1 - 9.8e-08 32.1 0.1 1.5e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 KDO26280.1 - 1.5e-05 24.8 1.1 1.5e-05 24.8 1.1 2.2 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KDO26280.1 - 0.002 17.9 0.5 0.002 17.9 0.5 1.8 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.25 KDO26281.1 - 6.8e-17 61.7 0.0 2.3e-07 30.5 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26281.1 - 7e-08 32.1 0.0 0.004 16.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO26281.1 - 0.00071 19.0 0.5 0.022 14.1 0.1 2.7 2 1 1 3 3 3 1 Kinase-like FYVE_2 PF02318.16 KDO26281.1 - 0.024 14.9 3.2 0.045 14.0 3.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger RIO1 PF01163.22 KDO26281.1 - 0.22 11.1 0.0 18 4.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family ArfGap PF01412.18 KDO26281.1 - 0.23 11.5 3.8 0.41 10.7 3.8 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Sp38 PF07354.12 KDO26281.1 - 0.58 9.6 4.3 1.1 8.6 4.3 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Kelch_4 PF13418.6 KDO26282.1 - 1.9e-17 63.0 0.2 1.4e-07 31.4 0.0 5.9 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO26282.1 - 2.7e-15 56.0 1.4 0.00038 20.4 0.0 6.2 5 2 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KDO26282.1 - 6e-12 45.5 15.2 0.0014 18.9 0.0 6.6 8 1 1 9 9 9 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO26282.1 - 3.4e-09 36.7 1.3 0.016 15.4 0.0 5.0 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KDO26282.1 - 4.8e-08 32.5 0.4 0.043 13.4 0.1 4.9 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KDO26282.1 - 5.2e-08 32.5 1.7 0.061 13.3 0.1 4.7 5 0 0 5 5 5 2 Kelch motif MFS_3 PF05977.13 KDO26283.1 - 0.046 12.1 0.0 0.055 11.9 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector DUF2700 PF10912.8 KDO26283.1 - 0.056 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) UPF0542 PF15086.6 KDO26283.1 - 0.061 13.3 0.1 0.072 13.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2178 PF09946.9 KDO26283.1 - 0.064 13.4 0.1 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Mak10 PF04112.13 KDO26284.1 - 4.1e-29 101.3 0.1 4e-27 94.8 0.1 2.4 1 1 0 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase RasGEF PF00617.19 KDO26285.1 - 0.026 14.7 1.8 0.056 13.7 0.1 2.0 1 1 1 2 2 2 0 RasGEF domain Nterm_IS4 PF13006.7 KDO26285.1 - 0.058 13.6 0.9 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal Imm6 PF14434.6 KDO26285.1 - 0.088 12.7 0.3 0.26 11.3 0.1 1.8 1 1 0 1 1 1 0 Immunity protein Imm6 UFD1 PF03152.14 KDO26286.1 - 1.9e-73 245.6 0.0 2.3e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF5088 PF17008.5 KDO26286.1 - 0.052 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) CDC48_2 PF02933.17 KDO26286.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 ASH PF15780.5 KDO26288.1 - 4e-09 36.6 8.6 1 9.6 0.0 7.0 7 0 0 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KDO26288.1 - 4.6e-05 23.5 2.9 6.7 6.9 0.0 4.6 4 0 0 4 4 4 3 Flagellar-associated PapD-like DUF1964 PF09244.10 KDO26288.1 - 0.061 13.8 0.4 2.6 8.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1964) TMEM131_like PF12371.8 KDO26288.1 - 0.2 11.9 2.4 59 4.0 0.1 4.7 4 1 1 5 5 5 0 Transmembrane protein 131-like PapD-like PF14874.6 KDO26289.1 - 0.0016 18.6 0.1 0.0036 17.4 0.1 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like Glutaredoxin PF00462.24 KDO26290.1 - 2.4e-15 56.5 0.0 5.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KDO26290.1 - 0.0025 18.2 0.2 0.0041 17.5 0.2 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) VWA_CoxE PF05762.14 KDO26290.1 - 0.047 13.1 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein TPP_enzyme_N PF02776.18 KDO26291.1 - 7.7e-56 188.4 0.1 3e-55 186.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KDO26291.1 - 1.8e-49 167.5 0.1 1.8e-47 161.0 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KDO26291.1 - 1e-44 151.6 0.1 2.1e-44 150.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KDO26291.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Peptidase_M1 PF01433.20 KDO26292.1 - 6.9e-83 277.5 4.6 1.2e-82 276.7 4.6 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KDO26292.1 - 1e-63 215.8 5.9 3.6e-63 214.0 5.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KDO26292.1 - 1.3e-40 139.6 0.0 3.1e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Gly_transf_sug PF04488.15 KDO26293.1 - 6.6e-12 45.9 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KDO26293.1 - 2.6e-05 23.8 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Methyltransf_16 PF10294.9 KDO26294.1 - 2.4e-12 46.9 0.0 1.3e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase AlaDh_PNT_C PF01262.21 KDO26294.1 - 0.055 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain START PF01852.19 KDO26295.1 - 1.8e-25 89.6 0.1 2.2e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 START domain Abhydrolase_6 PF12697.7 KDO26296.1 - 1.1e-09 39.2 4.1 1.6e-09 38.7 4.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO26296.1 - 6.4e-07 29.3 0.0 8.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.12 KDO26296.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Oxysterol_BP PF01237.18 KDO26297.1 - 9.7e-50 169.4 0.1 1.8e-40 139.0 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein SNARE_assoc PF09335.11 KDO26298.1 - 6.9e-09 36.2 0.9 6.9e-09 36.2 0.9 2.3 4 0 0 4 4 4 1 SNARE associated Golgi protein CS PF04969.16 KDO26300.1 - 1.2e-11 45.4 0.0 1.7e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 CS domain TTL PF03133.15 KDO26301.1 - 5e-88 295.0 3.4 7.2e-88 294.5 3.4 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO26301.1 - 2.7e-08 33.4 0.2 3.2e-05 23.3 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO26301.1 - 4.5e-05 22.9 0.0 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 KDO26301.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DSPn PF14671.6 KDO26302.1 - 6.2e-41 140.1 0.0 1.7e-40 138.7 0.0 1.8 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KDO26302.1 - 4.1e-14 52.5 0.0 7.7e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KDO26302.1 - 2e-05 24.8 0.0 8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KDO26302.1 - 2.8e-05 23.8 0.0 6.8e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KDO26302.1 - 0.23 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4307 PF14155.6 KDO26303.1 - 0.057 13.2 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) LapA_dom PF06305.11 KDO26303.1 - 0.065 13.1 0.3 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LRR_6 PF13516.6 KDO26304.1 - 2.7e-12 45.7 14.4 0.14 12.2 0.0 8.2 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 KDO26304.1 - 0.0001 22.3 5.9 67 4.6 0.2 7.4 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO26304.1 - 0.03 14.8 13.3 4 8.0 0.5 5.0 2 2 5 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26304.1 - 0.086 12.6 13.2 0.68 9.7 0.6 5.4 4 2 1 5 5 5 0 Leucine rich repeat Ras PF00071.22 KDO26305.1 - 1.2e-34 119.2 0.0 1.6e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO26305.1 - 1.8e-26 92.7 0.0 3.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO26305.1 - 4e-10 39.4 0.1 7.8e-10 38.5 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO26305.1 - 0.0025 17.2 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO26305.1 - 0.0086 16.1 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KDO26305.1 - 0.21 10.7 0.6 5.8 6.0 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Ank_4 PF13637.6 KDO26306.1 - 2.5e-18 66.2 5.5 6.2e-10 39.4 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26306.1 - 1.5e-15 57.5 2.3 3.6e-15 56.3 0.5 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO26306.1 - 3e-12 46.4 5.2 0.00014 22.1 0.3 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO26306.1 - 2.8e-11 42.6 2.8 0.00014 22.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO26306.1 - 5.5e-09 36.1 2.0 0.0011 19.3 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) DUF3037 PF11236.8 KDO26306.1 - 0.14 12.6 2.0 0.37 11.2 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Halo_GVPC PF05465.13 KDO26306.1 - 0.29 11.4 2.7 5.4 7.4 1.1 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat ubiquitin PF00240.23 KDO26307.1 - 0.072 12.9 0.1 0.13 12.1 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.8 KDO26307.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4485 PF14846.6 KDO26308.1 - 1.2e-16 60.5 0.1 3e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) FAM184 PF15665.5 KDO26308.1 - 0.0019 18.0 6.3 0.0026 17.6 6.3 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DUF4055 PF13264.6 KDO26308.1 - 0.011 15.9 0.7 0.018 15.2 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) GldM_N PF12081.8 KDO26308.1 - 0.044 13.9 0.6 0.065 13.3 0.6 1.2 1 0 0 1 1 1 0 GldM N-terminal domain YjbH PF06082.11 KDO26308.1 - 0.06 12.1 1.3 0.07 11.9 1.3 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Filament PF00038.21 KDO26308.1 - 0.076 12.6 8.8 0.079 12.5 3.5 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF16 PF01519.16 KDO26308.1 - 0.28 11.7 2.4 0.61 10.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 ADIP PF11559.8 KDO26308.1 - 0.32 11.1 8.1 0.51 10.4 8.0 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KDO26308.1 - 0.39 11.2 11.5 0.29 11.6 7.8 2.6 3 1 0 3 3 3 0 Cell division protein ZapB Pkinase PF00069.25 KDO26309.1 - 1.5e-48 165.5 0.0 1.9e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26309.1 - 5.6e-22 78.3 0.0 8.8e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO26309.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO26309.1 - 0.021 14.2 0.5 0.073 12.4 0.5 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_2 PF13923.6 KDO26310.1 - 1.6e-06 27.8 3.9 1.6e-06 27.8 3.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO26310.1 - 2.2e-06 27.8 0.5 2.2e-06 27.8 0.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KDO26310.1 - 1.5e-05 25.2 2.7 1.5e-05 25.2 2.7 2.5 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 KDO26310.1 - 5.3e-05 23.2 0.3 9.6e-05 22.3 0.3 1.4 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 KDO26310.1 - 8.2e-05 22.5 2.6 8.2e-05 22.5 2.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KDO26310.1 - 0.001 18.8 0.6 0.001 18.8 0.6 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO26310.1 - 0.0043 16.9 9.7 0.017 15.0 9.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO26310.1 - 0.0094 16.0 1.1 0.0094 16.0 1.1 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-Nse PF11789.8 KDO26310.1 - 0.036 13.9 0.8 0.12 12.2 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KDO26310.1 - 0.74 9.9 4.1 0.2 11.7 0.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO26310.1 - 1.4 8.6 6.9 1.6 8.4 0.9 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KDO26310.1 - 1.6 9.1 5.8 1.1 9.7 3.3 2.1 2 0 0 2 2 2 0 RING-like domain DUF1604 PF07713.13 KDO26311.1 - 1.6e-26 92.0 0.9 1.6e-26 92.0 0.9 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KDO26311.1 - 6.9e-07 29.1 0.7 1.5e-06 28.0 0.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KDO26311.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 0 G-patch domain SR-25 PF10500.9 KDO26311.1 - 0.31 10.6 40.6 0.059 13.0 35.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KDO26311.1 - 3.2 5.9 20.5 5 5.3 20.5 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KDO26311.1 - 5 6.9 16.0 8 6.2 16.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 KDO26312.1 - 6.5e-32 109.2 0.0 3.1e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO26312.1 - 1.7e-07 31.2 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif DUF4140 PF13600.6 KDO26312.1 - 0.0016 18.8 0.0 1 9.9 0.0 2.6 2 1 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Nup35_RRM_2 PF14605.6 KDO26312.1 - 0.046 13.7 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Keratin_2_head PF16208.5 KDO26312.1 - 4.8 7.3 35.1 12 6.0 35.1 1.6 1 0 0 1 1 1 0 Keratin type II head TM231 PF10149.9 KDO26313.1 - 6e-51 173.6 0.0 6.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 GRDP-like PF07173.12 KDO26314.1 - 2.9e-07 31.2 0.0 6.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like zinc_ribbon_12 PF11331.8 KDO26314.1 - 0.021 14.6 1.6 0.31 10.9 0.3 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KDO26314.1 - 0.039 14.1 3.6 5.2 7.3 0.2 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zf-FLZ PF04570.14 KDO26314.1 - 0.21 11.1 2.3 0.19 11.2 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DZR PF12773.7 KDO26314.1 - 2.2 8.4 7.6 2.3e+02 1.9 7.6 2.6 1 1 0 1 1 1 0 Double zinc ribbon BIR PF00653.21 KDO26314.1 - 5.7 7.7 7.7 39 5.0 0.2 3.4 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain HECT PF00632.25 KDO26316.1 - 4.6e-52 177.4 0.0 6.6e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 KDO26316.1 - 3.2e-11 43.3 0.6 8e-11 42.0 0.6 1.7 1 0 0 1 1 1 1 Mib_herc2 SPRY PF00622.28 KDO26316.1 - 1.5e-10 41.2 0.0 4.4e-08 33.3 0.0 3.1 2 1 0 2 2 2 1 SPRY domain SH3_3 PF08239.11 KDO26316.1 - 9.6e-05 22.6 0.0 0.0004 20.6 0.0 2.1 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KDO26316.1 - 0.0068 16.2 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Pkinase_Tyr PF07714.17 KDO26317.1 - 1.2e-28 100.1 0.1 1.2e-27 96.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26317.1 - 2.5e-28 99.2 0.0 2.4e-27 96.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26318.1 - 4.5e-33 114.6 0.0 5.5e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26318.1 - 2e-29 102.8 0.0 2.7e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KDO26320.1 - 6.2e-11 42.4 2.4 0.001 19.4 0.0 6.7 4 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO26320.1 - 1.7e-09 38.1 12.7 2.9e-05 24.7 0.3 7.8 8 0 0 8 8 8 1 WD domain, G-beta repeat Clathrin PF00637.20 KDO26320.1 - 0.016 15.1 3.8 0.18 11.7 0.5 3.1 1 1 1 3 3 3 0 Region in Clathrin and VPS TBPIP_N PF15517.6 KDO26320.1 - 0.016 15.2 1.2 12 5.9 0.1 4.5 5 0 0 5 5 5 0 TBP-interacting protein N-terminus WD40_3 PF15911.5 KDO26320.1 - 0.03 14.3 0.3 2.8 8.0 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Choline_transpo PF04515.12 KDO26321.1 - 1.2e-71 241.5 30.2 1.2e-71 241.5 30.2 1.8 2 0 0 2 2 2 1 Plasma-membrane choline transporter SPC12 PF06645.13 KDO26321.1 - 0.0069 16.4 0.5 0.0069 16.4 0.5 4.7 5 1 1 6 6 6 1 Microsomal signal peptidase 12 kDa subunit (SPC12) UL2 PF08196.11 KDO26321.1 - 0.18 11.7 4.1 24 5.0 2.4 3.0 2 0 0 2 2 2 0 UL2 protein JHY PF15261.6 KDO26322.1 - 1.5e-17 64.5 7.8 1.5e-17 64.5 7.8 2.2 2 0 0 2 2 2 1 Jhy protein APG12 PF04110.13 KDO26323.1 - 1e-29 102.8 0.0 1.1e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KDO26323.1 - 4.5e-06 26.8 0.0 4.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Cyclin_N PF00134.23 KDO26324.1 - 7.2e-12 45.2 0.8 1.5e-11 44.2 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain CorA PF01544.18 KDO26325.1 - 3.9e-41 141.3 0.8 1.3e-34 119.9 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_1 PF00036.32 KDO26325.1 - 1.3e-05 24.4 2.7 1.9e-05 23.8 0.2 2.6 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KDO26325.1 - 1.5e-05 25.3 0.3 5.2e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO26325.1 - 3.1e-05 23.7 0.3 0.00028 20.7 0.1 2.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO26325.1 - 5.9e-05 22.4 0.1 0.00016 21.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO26325.1 - 8.6e-05 22.2 0.4 0.0051 16.7 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain DNA_pol_A_exo1 PF01612.20 KDO26325.1 - 0.035 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease DUF2207 PF09972.9 KDO26325.1 - 0.076 11.8 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cyclin_N PF00134.23 KDO26328.1 - 2.1e-07 30.7 0.1 3.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KDO26328.1 - 4e-07 30.5 0.0 5.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Sec10 PF07393.11 KDO26329.1 - 8.2e-75 252.6 2.8 4.9e-73 246.7 2.8 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec10 Flagellar_rod PF05149.12 KDO26329.1 - 0.076 12.5 0.4 0.13 11.7 0.4 1.4 1 0 0 1 1 1 0 Paraflagellar rod protein MscS_porin PF12795.7 KDO26329.1 - 2.5 7.6 10.2 1.2 8.6 3.7 2.7 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DAO PF01266.24 KDO26330.1 - 9.4e-56 189.9 0.0 1.1e-55 189.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO26330.1 - 5.8e-10 38.9 0.0 2.8e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KDO26330.1 - 5.7e-08 32.3 0.0 1.2e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KDO26330.1 - 6.1e-08 32.8 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KDO26330.1 - 2.8e-06 26.3 0.2 0.033 12.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KDO26330.1 - 1.4e-05 25.6 0.0 0.00075 20.0 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KDO26330.1 - 3.9e-05 23.3 0.3 7.3e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KDO26330.1 - 0.0011 18.3 0.1 0.0035 16.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KDO26330.1 - 0.0016 17.7 0.0 0.048 12.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO26330.1 - 0.0073 15.4 0.2 0.65 9.0 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 KDO26330.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KDO26330.1 - 0.021 14.1 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KDO26330.1 - 0.024 13.9 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KDO26330.1 - 0.046 13.1 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KDO26330.1 - 0.063 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KDO26330.1 - 0.068 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain FMO-like PF00743.19 KDO26330.1 - 0.14 10.5 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 KDO26330.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_S6e PF01092.19 KDO26330.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e 3HCDH_N PF02737.18 KDO26330.1 - 0.17 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KDO26331.1 - 3.8e-50 171.4 0.0 5.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO26331.1 - 6.8e-10 38.6 0.6 6.6e-05 22.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO26331.1 - 1.3e-07 31.7 0.5 4.8e-07 29.9 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KDO26331.1 - 3.6e-07 29.6 1.0 0.00025 20.3 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KDO26331.1 - 5.3e-06 25.4 0.6 0.01 14.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KDO26331.1 - 1e-05 24.9 0.0 0.00035 19.9 0.0 2.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 KDO26331.1 - 2.1e-05 25.0 1.1 0.0052 17.3 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO26331.1 - 7.5e-05 22.3 0.0 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KDO26331.1 - 0.00075 19.1 0.7 0.0014 18.3 0.7 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KDO26331.1 - 0.01 15.0 1.3 1.2 8.2 1.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KDO26331.1 - 0.013 14.8 0.4 0.047 12.9 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KDO26331.1 - 0.027 14.1 0.5 0.046 13.4 0.5 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KDO26331.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.24 KDO26331.1 - 0.04 13.2 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Epimerase PF01370.21 KDO26331.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 KDO26331.1 - 0.07 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KDO26331.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KDO26331.1 - 0.43 9.4 2.1 4 6.2 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase NadA PF02445.16 KDO26332.1 - 5.5e-33 114.4 0.1 6.4e-32 110.9 0.1 2.1 1 1 0 1 1 1 1 Quinolinate synthetase A protein Tub PF01167.18 KDO26333.1 - 1.7e-57 194.9 0.1 2.8e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 KDO26333.1 - 0.0027 17.3 0.1 0.0027 17.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) TPR_2 PF07719.17 KDO26334.1 - 5.6e-13 47.9 12.3 0.00081 19.3 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26334.1 - 2.9e-08 33.2 9.5 0.028 14.3 0.9 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26334.1 - 6.7e-06 26.7 18.0 8.6e-05 23.1 9.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26334.1 - 1.4e-05 24.9 6.4 0.044 14.0 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26334.1 - 0.00031 20.9 0.3 0.012 15.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26334.1 - 0.00051 19.7 4.4 0.033 13.9 0.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 KDO26334.1 - 0.001 19.7 15.0 0.8 10.7 1.0 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26334.1 - 0.0014 18.9 12.2 0.46 10.8 5.3 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO26334.1 - 0.054 13.6 8.5 0.054 13.6 3.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26334.1 - 0.06 13.4 6.1 13 6.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26334.1 - 0.23 12.0 10.6 0.73 10.4 4.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26334.1 - 2 9.2 9.7 1.9 9.3 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO26334.1 - 2.5 8.1 13.8 0.73 9.8 0.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO26334.1 - 3.9 7.8 7.3 25 5.2 0.7 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DASH_Dad4 PF08650.10 KDO26335.1 - 1.1e-15 57.3 0.1 1.2e-15 57.2 0.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 WXG100 PF06013.12 KDO26335.1 - 0.053 13.8 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Ank_4 PF13637.6 KDO26336.1 - 1.6e-24 85.9 14.2 1.8e-06 28.4 0.5 6.2 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26336.1 - 9.9e-23 80.5 9.9 6.3e-08 33.1 0.1 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26336.1 - 3.2e-16 59.2 17.7 0.0066 16.7 0.0 8.5 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26336.1 - 1.6e-11 43.3 10.6 9.3 7.2 0.0 9.1 9 1 1 10 10 10 4 Ankyrin repeat DUF5049 PF16468.5 KDO26336.1 - 6.5e-05 22.8 1.3 18 5.3 0.0 6.1 2 1 5 7 7 7 1 Domain of unknown function (DUF5049) DUF3322 PF11795.8 KDO26336.1 - 0.0007 19.7 5.6 16 5.4 0.0 5.9 1 1 5 6 6 6 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank PF00023.30 KDO26336.1 - 0.022 15.2 4.0 42 4.8 0.4 5.6 1 1 3 4 4 4 0 Ankyrin repeat RET_CLD1 PF17756.1 KDO26336.1 - 0.15 12.3 0.1 0.8 10.0 0.1 2.1 2 0 0 2 2 2 0 RET Cadherin like domain 1 HEAT_2 PF13646.6 KDO26337.1 - 0.0024 18.2 0.5 0.19 12.1 0.1 3.5 3 1 1 4 4 4 1 HEAT repeats CENP-B_dimeris PF09026.10 KDO26337.1 - 0.77 10.2 12.4 0.054 13.9 1.8 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 KDO26337.1 - 9.2 6.3 7.1 1.9 8.5 0.5 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal Actin PF00022.19 KDO26338.1 - 3.3e-18 65.5 0.0 6.5e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Actin zf-C4H2 PF10146.9 KDO26338.1 - 4.2 7.6 18.1 0.29 11.4 0.4 3.6 3 1 1 4 4 4 0 Zinc finger-containing protein PKcGMP_CC PF16808.5 KDO26338.1 - 8.9 6.3 10.0 0.86 9.5 0.3 3.9 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank_2 PF12796.7 KDO26340.1 - 8.5e-33 112.8 3.4 3.8e-13 49.8 0.1 3.7 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26340.1 - 2.5e-24 85.0 6.9 5.6e-09 36.1 0.0 5.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO26340.1 - 1.9e-23 82.5 7.5 4.7e-08 33.4 0.8 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 KDO26340.1 - 3.2e-23 82.3 14.0 2.2e-21 76.3 14.0 2.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase Ank_3 PF13606.6 KDO26340.1 - 7.7e-22 75.0 7.2 0.00059 20.1 0.0 7.8 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KDO26340.1 - 1.8e-14 53.4 22.4 0.0027 18.1 0.1 7.2 7 1 1 8 8 8 5 Ankyrin repeat B12D PF06522.11 KDO26340.1 - 0.041 13.7 0.0 9.6 6.1 0.0 2.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit LRR_8 PF13855.6 KDO26341.1 - 3.6e-18 65.1 21.7 2.9e-09 36.5 3.8 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO26341.1 - 2.8e-14 53.0 6.1 9.1e-06 25.9 2.8 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO26341.1 - 5.8e-13 47.8 7.6 0.045 13.8 0.3 5.4 4 1 1 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KDO26341.1 - 8e-10 37.9 0.9 3.4 8.6 0.1 5.2 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_9 PF14580.6 KDO26341.1 - 0.0046 16.5 0.2 0.0076 15.8 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KDO26342.1 - 9.6e-09 34.9 11.0 3.9e-05 23.3 4.6 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO26342.1 - 1.7e-08 34.6 13.1 0.00055 20.3 0.7 3.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO26342.1 - 8.3e-06 25.5 8.9 2.3 8.5 0.0 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KDO26342.1 - 0.0065 16.9 6.4 55 4.9 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat FNIP PF05725.12 KDO26342.1 - 0.17 12.1 4.7 5.9 7.1 0.4 3.1 3 0 0 3 3 3 0 FNIP Repeat LRR_8 PF13855.6 KDO26343.1 - 1.4e-12 47.2 13.8 4.7e-08 32.7 5.4 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO26343.1 - 2.2e-12 47.0 15.0 2.4e-06 27.8 0.3 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO26343.1 - 1.9e-09 36.8 11.7 0.11 12.6 0.5 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KDO26343.1 - 7.8e-07 28.8 8.6 3.3 8.6 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 KDO26343.1 - 0.0022 17.6 2.1 0.0069 15.9 1.1 2.2 2 1 0 2 2 2 1 Leucine-rich repeat FNIP PF05725.12 KDO26343.1 - 0.0064 16.6 4.9 1.5 9.1 4.9 2.7 1 1 0 1 1 1 1 FNIP Repeat DUF240 PF03086.14 KDO26343.1 - 0.14 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF240) MAPEG PF01124.18 KDO26344.1 - 2.1e-16 60.0 1.9 2.8e-16 59.6 1.9 1.2 1 0 0 1 1 1 1 MAPEG family Ank_4 PF13637.6 KDO26345.1 - 4.7e-15 55.7 4.7 8.4e-09 35.8 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26345.1 - 4.5e-13 49.6 0.0 2e-05 25.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26345.1 - 6.3e-13 48.7 0.2 1.9e-06 28.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO26345.1 - 2.1e-12 46.9 1.1 0.00086 19.7 0.3 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KDO26345.1 - 7.3e-12 44.4 0.5 8.7e-05 22.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat NOA36 PF06524.12 KDO26345.1 - 6.1 6.1 11.1 10 5.4 11.1 1.3 1 0 0 1 1 1 0 NOA36 protein Spermine_synth PF01564.17 KDO26346.1 - 4.2e-65 218.7 0.0 9.6e-65 217.5 0.0 1.6 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KDO26346.1 - 1e-20 73.3 0.2 1.8e-20 72.5 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KDO26346.1 - 0.0002 22.0 0.0 0.0011 19.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO26346.1 - 0.00089 20.0 0.0 0.0056 17.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KDO26346.1 - 0.0046 17.9 0.0 0.013 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 KDO26346.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 KDO26346.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Vps52 PF04129.12 KDO26347.1 - 8.5e-128 427.3 2.0 1.2e-127 426.7 2.0 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KDO26347.1 - 4.1e-09 35.4 1.0 2.7e-07 29.4 0.7 2.6 2 1 0 2 2 2 2 Exocyst complex component Sec3 COG2 PF06148.11 KDO26347.1 - 0.0011 19.1 1.1 0.0035 17.4 1.1 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG6 PF06419.11 KDO26347.1 - 0.0032 15.8 0.7 0.021 13.1 0.0 2.2 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 baeRF_family11 PF18855.1 KDO26347.1 - 0.031 14.6 0.2 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 HSCB_C PF07743.13 KDO26348.1 - 3.8e-18 65.7 0.4 5e-18 65.4 0.4 1.2 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain Ephrin_rec_like PF07699.13 KDO26349.1 - 4.2e-05 23.2 9.8 0.00033 20.4 0.6 2.9 3 0 0 3 3 3 2 Putative ephrin-receptor like NCD3G PF07562.14 KDO26349.1 - 0.0046 16.9 9.4 0.12 12.3 0.5 2.6 2 0 0 2 2 2 2 Nine Cysteines Domain of family 3 GPCR Laminin_G_3 PF13385.6 KDO26350.1 - 1.9e-23 83.3 14.9 1.3e-12 48.1 0.1 5.4 3 1 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.20 KDO26350.1 - 3.3e-12 46.7 0.0 0.0029 17.9 0.0 5.4 5 0 0 5 5 5 3 CUB domain Beta_helix PF13229.6 KDO26350.1 - 8.5e-11 41.9 14.7 7.7e-05 22.6 10.0 3.2 1 1 1 2 2 2 2 Right handed beta helix region Laminin_G_2 PF02210.24 KDO26350.1 - 2.1e-05 25.1 0.0 0.0015 19.1 0.0 2.6 2 0 0 2 2 2 1 Laminin G domain Topo_Zn_Ribbon PF08272.11 KDO26350.1 - 0.017 14.7 0.4 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like EGF_Tenascin PF18720.1 KDO26350.1 - 0.33 11.1 11.3 0.35 11.0 9.0 2.5 2 0 0 2 2 2 0 Tenascin EGF domain EGF_2 PF07974.13 KDO26350.1 - 2.4 8.6 22.9 0.013 15.8 11.7 2.9 2 0 0 2 2 2 0 EGF-like domain Ank_5 PF13857.6 KDO26351.1 - 3.4e-10 40.0 5.3 0.041 14.2 0.0 5.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26351.1 - 3.6e-10 40.3 1.1 3.3e-06 27.6 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26351.1 - 9.5e-10 38.8 6.3 0.00036 21.0 0.3 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26351.1 - 4.7e-08 32.7 1.9 4.9 8.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO26351.1 - 0.04 14.4 3.6 10 6.8 0.5 4.3 2 1 0 2 2 2 0 Ankyrin repeat RB_A PF01858.17 KDO26352.1 - 6.5e-56 189.3 0.0 1.4e-55 188.2 0.0 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KDO26352.1 - 1.2e-32 112.7 0.3 2.9e-32 111.5 0.3 1.7 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KDO26352.1 - 8e-16 57.8 0.0 2.2e-12 46.7 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3452) Rb_C PF08934.10 KDO26352.1 - 2.9e-06 27.2 0.1 6.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Rb C-terminal domain LRS4 PF10422.9 KDO26352.1 - 0.27 10.8 6.2 0.09 12.3 1.6 2.1 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Kinesin PF00225.23 KDO26353.1 - 2e-109 365.6 0.7 2e-109 365.6 0.7 2.6 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KDO26353.1 - 1.7e-26 92.9 0.0 8e-26 90.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding HMMR_C PF15908.5 KDO26353.1 - 8.2e-07 29.4 14.7 8.2e-07 29.4 14.7 5.2 4 2 2 6 6 6 1 Hyaluronan mediated motility receptor C-terminal TMF_TATA_bd PF12325.8 KDO26353.1 - 0.00033 20.9 2.1 0.00033 20.9 2.1 10.2 3 2 8 12 12 12 3 TATA element modulatory factor 1 TATA binding KIAA1430 PF13879.6 KDO26353.1 - 0.17 12.7 14.3 0.034 14.9 9.3 2.6 2 0 0 2 2 2 0 KIAA1430 homologue FlaC_arch PF05377.11 KDO26353.1 - 1.9 9.0 20.0 5.7 7.4 0.1 8.9 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) Exonuc_VII_S PF02609.16 KDO26353.1 - 4 7.6 9.7 3.9 7.6 0.3 4.5 4 0 0 4 4 4 0 Exonuclease VII small subunit Pkinase PF00069.25 KDO26354.1 - 1.5e-17 63.9 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26354.1 - 2e-17 63.3 0.0 5.2e-17 62.0 0.0 1.5 1 1 0 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO26354.1 - 5.4e-09 36.2 10.8 0.00019 21.7 5.0 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26354.1 - 6.7e-09 35.4 8.1 0.00045 19.9 2.0 2.7 2 0 0 2 2 2 2 Leucine rich repeat DBB PF14545.6 KDO26354.1 - 9.6e-05 22.3 0.3 0.00054 19.9 0.1 2.1 2 0 0 2 2 2 1 Dof, BCAP, and BANK (DBB) motif, LRR_6 PF13516.6 KDO26354.1 - 0.0011 18.8 5.1 5.9 7.2 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat Kinase-like PF14531.6 KDO26354.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 KDO26354.1 - 0.061 13.9 4.3 23 6.1 0.0 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 KDO26355.1 - 2.7e-14 53.1 0.0 1.8e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO26355.1 - 1.4e-07 31.2 0.0 1.2e-06 28.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26356.1 - 2.5e-08 33.5 0.0 2.5e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO26356.1 - 6.6e-05 22.4 0.0 0.0047 16.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain UPF0560 PF10577.9 KDO26356.1 - 0.0062 15.1 1.1 0.0079 14.8 1.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 EphA2_TM PF14575.6 KDO26356.1 - 0.029 15.3 0.1 0.053 14.4 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kinase-like PF14531.6 KDO26356.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1656 PF07869.12 KDO26356.1 - 0.13 12.2 2.7 11 6.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) PMP1_2 PF08114.11 KDO26356.1 - 0.73 9.6 3.5 1.2 8.9 3.5 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Pkinase_Tyr PF07714.17 KDO26357.1 - 8.7e-19 67.8 0.0 9.2e-16 57.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO26357.1 - 3.4e-12 46.3 0.0 4.9e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Cu-binding_MopE PF11617.8 KDO26357.1 - 0.065 13.4 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Putative metal-binding motif LRR_4 PF12799.7 KDO26358.1 - 1.1e-15 57.5 10.6 9.8e-08 32.2 0.5 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26358.1 - 8.6e-15 54.2 14.7 2.3e-08 33.7 5.1 3.5 1 1 1 3 3 3 3 Leucine rich repeat Pkinase_Tyr PF07714.17 KDO26358.1 - 2.1e-13 50.2 0.0 1.5e-11 44.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO26358.1 - 3.7e-08 33.0 0.0 5.7e-07 29.2 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain LRR_6 PF13516.6 KDO26358.1 - 5.5e-08 32.3 10.1 0.19 11.9 0.0 5.9 4 1 1 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 KDO26358.1 - 1.9e-06 27.5 0.9 1.6e-05 24.5 0.6 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KDO26358.1 - 5e-05 23.3 6.3 7.6 7.5 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat RRM_1 PF00076.22 KDO26359.1 - 4.8e-10 39.1 0.0 6.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Polysacc_deac_1 PF01522.21 KDO26360.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 KDO26361.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase BTB_2 PF02214.22 KDO26362.1 - 2.3e-13 50.3 0.0 3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KDO26362.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 BTB/POZ domain PanZ PF12568.8 KDO26363.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MDD_C PF18376.1 KDO26364.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain ANAPC4_WD40 PF12894.7 KDO26365.1 - 0.23 11.8 0.8 34 4.8 0.1 3.3 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA_Me_trans PF03054.16 KDO26366.1 - 9.2e-98 327.3 0.0 2.6e-95 319.2 0.0 2.1 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KDO26366.1 - 5.4e-07 29.0 0.0 1.6e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 KDO26366.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KDO26366.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ThiI PF02568.14 KDO26366.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Pkinase PF00069.25 KDO26367.1 - 9.5e-18 64.5 0.0 1.8e-17 63.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26367.1 - 6e-09 35.6 0.0 2.1e-08 33.8 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase PLU-1 PF08429.11 KDO26368.1 - 0.0021 17.3 2.4 0.0024 17.1 2.4 1.0 1 0 0 1 1 1 1 PLU-1-like protein Mto2_bdg PF12808.7 KDO26368.1 - 0.061 13.6 1.1 0.14 12.5 1.1 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Occludin_ELL PF07303.13 KDO26368.1 - 0.079 13.7 6.3 1 10.1 7.3 2.0 1 1 0 1 1 1 0 Occludin homology domain DUF883 PF05957.13 KDO26368.1 - 0.4 11.3 7.2 1.1 9.9 4.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.25 KDO26369.1 - 8.7e-72 241.6 0.0 1.1e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26369.1 - 3.9e-42 144.3 0.0 5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO26369.1 - 7.4e-07 28.8 0.0 1.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO26369.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO26369.1 - 0.0072 15.2 0.1 0.02 13.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KDO26369.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Antimicrobial_2 PF08023.12 KDO26369.1 - 0.21 12.1 0.3 0.51 10.9 0.0 1.8 2 0 0 2 2 2 0 Frog antimicrobial peptide Pkinase PF00069.25 KDO26370.1 - 2.9e-74 249.8 0.0 3.5e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26370.1 - 4.6e-47 160.5 0.0 5.7e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO26370.1 - 1.3e-05 24.6 0.1 2.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO26370.1 - 2.7e-05 23.7 0.1 0.00024 20.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KDO26370.1 - 0.00028 20.0 0.1 0.00038 19.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO26370.1 - 0.0023 17.0 0.1 0.0036 16.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KDO26370.1 - 0.004 16.8 2.1 0.011 15.3 2.1 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KDO26370.1 - 0.012 15.5 2.4 0.025 14.5 0.5 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO26370.1 - 0.014 14.2 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1329 PF07044.11 KDO26370.1 - 0.073 12.3 1.2 0.11 11.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) YrbL-PhoP_reg PF10707.9 KDO26370.1 - 0.077 12.5 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CLASP_N PF12348.8 KDO26371.1 - 2.4e-08 33.8 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal ABC_membrane_3 PF13748.6 KDO26371.1 - 0.089 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region HEAT PF02985.22 KDO26371.1 - 0.36 11.2 3.1 21 5.7 0.2 3.0 2 0 0 2 2 2 0 HEAT repeat ERCC4 PF02732.15 KDO26372.1 - 3.2e-18 66.4 0.0 5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KDO26372.1 - 2.4e-07 31.0 0.9 6e-07 29.7 0.9 1.8 1 1 0 1 1 1 1 Helix-hairpin-helix domain TPR_2 PF07719.17 KDO26373.1 - 8.4e-15 53.6 0.1 0.0012 18.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat FYVE PF01363.21 KDO26373.1 - 2.2e-12 46.9 12.6 3.7e-12 46.2 12.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_11 PF13414.6 KDO26373.1 - 6.2e-12 45.0 2.6 6.7e-06 25.7 0.3 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 KDO26373.1 - 1.2e-11 43.9 0.1 7.4e-05 22.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26373.1 - 5.3e-09 36.2 2.7 0.0055 17.0 0.0 3.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Ank_5 PF13857.6 KDO26373.1 - 3.3e-08 33.6 0.1 0.0045 17.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TPR_8 PF13181.6 KDO26373.1 - 7.7e-08 32.0 0.1 0.0013 18.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26373.1 - 2.3e-07 31.4 13.3 4.6e-05 24.0 1.2 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO26373.1 - 1.5e-06 28.5 11.1 0.0049 17.6 0.1 4.6 3 1 2 5 5 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26373.1 - 1.9e-05 24.3 2.1 0.059 13.4 0.0 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26373.1 - 2.1e-05 24.9 0.9 6.8 7.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank_2 PF12796.7 KDO26373.1 - 0.00014 22.4 0.0 0.00029 21.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_9 PF13371.6 KDO26373.1 - 0.00028 21.0 1.8 0.0022 18.1 1.3 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO26373.1 - 0.00034 20.4 1.8 5.3 7.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26373.1 - 0.00053 20.2 0.1 0.024 15.0 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26373.1 - 0.0006 20.3 1.0 0.0006 20.3 1.0 2.9 2 1 0 3 3 2 1 Tetratricopeptide repeat Ank_4 PF13637.6 KDO26373.1 - 0.0015 19.0 0.1 0.0043 17.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ANAPC3 PF12895.7 KDO26373.1 - 0.0017 18.6 0.1 0.0051 17.0 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KDO26373.1 - 0.05 13.3 0.9 0.096 12.4 0.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Ank PF00023.30 KDO26373.1 - 0.17 12.4 0.5 4.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Caskin-Pro-rich PF16907.5 KDO26373.1 - 0.79 10.3 6.6 0.62 10.6 3.6 2.3 2 0 0 2 2 2 0 Proline rich region of Caskin proteins UL42 PF17638.2 KDO26373.1 - 5.7 6.9 11.0 0.22 11.5 1.6 2.6 2 0 0 2 2 2 0 HCMV UL42 Golgin_A5 PF09787.9 KDO26374.1 - 0.023 14.2 4.2 0.035 13.6 4.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4763 PF15960.5 KDO26374.1 - 0.12 11.7 0.4 0.2 10.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YwqJ-deaminase PF14431.6 KDO26374.1 - 0.17 12.0 1.3 0.35 11.0 1.3 1.5 1 0 0 1 1 1 0 YwqJ-like deaminase FlxA PF14282.6 KDO26374.1 - 0.38 10.8 3.9 0.13 12.3 0.9 1.7 2 0 0 2 2 2 0 FlxA-like protein Filament PF00038.21 KDO26374.1 - 0.44 10.1 4.9 0.67 9.5 4.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 KDO26374.1 - 0.6 8.9 5.2 0.9 8.4 5.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlgN PF05130.12 KDO26374.1 - 1.7 9.1 10.5 3.6 8.1 10.5 1.5 1 0 0 1 1 1 0 FlgN protein MFS_1 PF07690.16 KDO26375.1 - 9.5e-25 87.3 28.4 9.5e-25 87.3 28.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO26375.1 - 8.8e-10 38.0 15.7 1.3e-08 34.2 6.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 KDO26375.1 - 0.011 14.7 13.9 0.17 10.8 2.1 2.3 2 0 0 2 2 2 0 Nucleoside H+ symporter DUF3925 PF13063.6 KDO26375.1 - 0.051 13.8 0.4 0.16 12.2 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Nuc_recep-AF1 PF11825.8 KDO26375.1 - 0.058 13.4 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 DUF2838 PF10998.8 KDO26375.1 - 0.96 9.7 6.2 1.9 8.7 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2838) MFS_1 PF07690.16 KDO26376.1 - 3.5e-16 59.1 41.1 4.8e-16 58.6 40.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NDUF_B12 PF08122.12 KDO26376.1 - 2.8 8.1 8.2 1.8 8.7 0.1 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4538 PF15061.6 KDO26376.1 - 7.9 6.3 5.8 1.8 8.4 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Pro_isomerase PF00160.21 KDO26377.1 - 7.6e-44 149.8 0.8 1.3e-43 149.0 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HEPN_Swt1 PF18731.1 KDO26377.1 - 0.48 10.8 5.3 1.6 9.1 4.6 2.4 1 1 0 1 1 1 0 Swt1-like HEPN DUF4265 PF14085.6 KDO26378.1 - 0.0069 16.3 0.1 0.017 15.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4265) Ribosomal_S10 PF00338.22 KDO26379.1 - 6.4e-28 96.9 0.0 8e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Flavin_Reduct PF01613.18 KDO26380.1 - 2.7e-10 40.5 0.0 3.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain bZIP_1 PF00170.21 KDO26381.1 - 0.0052 16.9 1.5 2.4 8.3 0.1 3.2 2 0 0 2 2 2 2 bZIP transcription factor Baculo_PEP_C PF04513.12 KDO26381.1 - 0.16 12.0 12.9 4.3 7.4 0.0 4.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL32 PF15225.6 KDO26381.1 - 0.18 12.2 0.8 11 6.4 0.2 2.7 2 0 0 2 2 2 0 Interleukin 32 DUF4763 PF15960.5 KDO26381.1 - 2.4 7.4 10.0 0.33 10.2 3.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) ADIP PF11559.8 KDO26381.1 - 3.4 7.7 14.3 0.04 14.0 1.1 3.5 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding MFS_1 PF07690.16 KDO26382.1 - 9.6e-11 41.2 41.4 3.1e-10 39.5 21.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO26382.1 - 0.0042 16.0 10.7 0.0042 16.0 10.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO26383.1 - 1.1e-11 44.3 45.1 6.8e-09 35.1 24.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO26383.1 - 0.00051 19.0 12.1 0.00051 19.0 12.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter PhoD PF09423.10 KDO26384.1 - 9.9e-14 51.1 0.4 1.9e-13 50.2 0.4 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase Flavin_Reduct PF01613.18 KDO26385.1 - 2.3e-19 70.0 0.1 3.1e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KDO26385.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Peptidase_S3 PF00944.19 KDO26386.1 - 0.14 11.9 2.3 47 3.7 0.1 4.1 4 1 0 4 4 4 0 Alphavirus core protein Lactamase_B PF00753.27 KDO26387.1 - 8.9e-10 38.9 7.8 5.3e-08 33.1 7.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KDO26387.1 - 4.1e-05 24.0 0.0 8.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus dUTPase_2 PF08761.11 KDO26388.1 - 0.0078 16.4 8.5 0.018 15.2 8.1 2.0 1 1 1 2 2 2 1 dUTPase Aminotran_1_2 PF00155.21 KDO26389.1 - 3.4e-74 250.2 0.1 7e-74 249.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KDO26389.1 - 4.5e-05 22.2 0.0 7.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KDO26389.1 - 0.00046 19.3 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 KDO26389.1 - 0.13 12.8 2.2 0.27 11.7 2.2 1.5 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence SIKE PF05769.11 KDO26390.1 - 0.0024 17.8 1.4 0.0024 17.8 1.4 1.5 2 0 0 2 2 2 1 SIKE family TFIIA PF03153.13 KDO26390.1 - 0.077 13.0 10.8 0.098 12.6 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0262 PF06793.12 KDO26390.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Macoilin PF09726.9 KDO26390.1 - 0.17 10.4 7.1 0.24 9.9 7.1 1.1 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 KDO26390.1 - 0.65 9.3 9.7 1 8.6 9.7 1.2 1 0 0 1 1 1 0 FAM76 protein Oxidored_q6 PF01058.22 KDO26391.1 - 3.5e-23 81.9 0.0 4.7e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 KDO26391.1 - 0.029 14.2 0.5 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Honey bee peptides IQ PF00612.27 KDO26392.1 - 1.7e-05 24.2 22.4 0.0098 15.6 1.3 5.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif DZR PF12773.7 KDO26392.1 - 0.097 12.7 1.5 0.24 11.5 1.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon ELYS PF13934.6 KDO26392.1 - 3.7 7.5 6.5 0.48 10.4 1.0 2.3 2 0 0 2 2 2 0 Nuclear pore complex assembly Mannosyl_trans3 PF11051.8 KDO26393.1 - 1.9e-35 122.6 0.0 1.1e-23 84.0 0.0 2.3 2 1 0 2 2 2 2 Mannosyltransferase putative START PF01852.19 KDO26394.1 - 2e-06 27.4 0.1 4.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO26394.1 - 0.0041 17.3 12.4 0.0049 17.1 10.3 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 KDO26394.1 - 0.13 12.4 13.1 0.44 10.7 13.1 1.9 1 1 0 1 1 1 0 FYVE zinc finger START PF01852.19 KDO26395.1 - 9.5e-11 41.5 0.8 6e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 START domain C1_2 PF03107.16 KDO26395.1 - 0.005 17.1 2.7 0.012 16.0 2.7 1.6 1 0 0 1 1 1 1 C1 domain FYVE_2 PF02318.16 KDO26395.1 - 0.017 15.3 6.9 0.032 14.4 6.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KDO26395.1 - 0.029 14.5 8.8 0.064 13.4 8.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger DUF2318 PF10080.9 KDO26395.1 - 0.76 9.9 5.3 0.32 11.1 2.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-piccolo PF05715.13 KDO26395.1 - 6 7.1 8.8 0.43 10.8 3.8 1.7 2 0 0 2 2 2 0 Piccolo Zn-finger FYVE PF01363.21 KDO26396.1 - 3.2e-09 36.8 15.5 5.8e-09 36.0 15.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO26396.1 - 1.6e-08 34.2 0.6 3.7e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 START domain FYVE_2 PF02318.16 KDO26396.1 - 0.001 19.3 10.3 0.0011 19.2 8.5 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 KDO26397.1 - 3.6e-09 36.6 11.4 8.7e-09 35.4 11.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO26397.1 - 0.00041 20.5 8.4 0.00089 19.5 8.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger GFA PF04828.14 KDO26398.1 - 6.4e-08 32.8 0.9 6.4e-08 32.8 0.9 2.4 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.13 KDO26401.1 - 1e-06 28.7 4.0 1.9e-05 24.6 2.2 1.8 1 1 1 2 2 2 2 CHCH domain Cmc1 PF08583.10 KDO26401.1 - 0.00011 22.2 0.4 0.028 14.5 0.1 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KDO26401.1 - 0.00019 21.6 1.6 0.00024 21.3 1.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KDO26401.1 - 0.00045 20.2 1.1 0.58 10.2 0.0 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 KDO26401.1 - 0.00099 19.4 2.2 0.37 11.2 0.9 2.2 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KDO26401.1 - 0.0012 19.0 3.3 0.47 10.7 1.2 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 KDO26401.1 - 0.0029 17.9 0.1 0.0039 17.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) NDUF_B7 PF05676.13 KDO26401.1 - 0.3 10.9 4.7 1.5 8.6 4.7 1.8 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) RRM_1 PF00076.22 KDO26402.1 - 3.2e-09 36.5 0.0 8.5e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1176 PF06674.11 KDO26402.1 - 0.011 15.1 0.2 0.016 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Acetyltransf_16 PF05301.11 KDO26403.1 - 8.6e-46 155.9 0.0 1e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_6 PF13480.7 KDO26403.1 - 0.065 13.4 0.4 0.11 12.6 0.4 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Transcrip_reg PF01709.20 KDO26404.1 - 3.4e-72 242.7 0.2 4e-72 242.5 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator Glyoxalase_3 PF13468.6 KDO26404.1 - 0.0087 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain CUE PF02845.16 KDO26406.1 - 9.1e-08 31.7 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF2457 PF10446.9 KDO26406.1 - 0.00024 20.4 10.4 0.00032 20.0 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 KDO26406.1 - 0.09 11.0 8.6 0.11 10.7 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KDO26406.1 - 0.18 11.2 8.0 0.21 11.0 8.0 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KDO26406.1 - 0.81 7.7 17.1 1.1 7.3 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KDO26406.1 - 0.9 8.8 6.1 1.1 8.6 6.1 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 KDO26406.1 - 6.8 6.7 8.1 13 5.8 8.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PhoD PF09423.10 KDO26408.1 - 1.5e-13 50.5 0.4 9.3e-12 44.6 0.4 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase zf-TAZ PF02135.16 KDO26410.1 - 6.2e-07 29.8 7.5 6.2e-07 29.8 7.5 3.4 3 0 0 3 3 3 2 TAZ zinc finger PWWP PF00855.17 KDO26410.1 - 0.00016 22.0 0.5 0.00058 20.2 0.5 1.9 1 0 0 1 1 1 1 PWWP domain VPS13_C PF16909.5 KDO26411.1 - 5.8e-61 205.4 9.0 2.3e-59 200.2 1.6 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 KDO26411.1 - 1.8e-40 139.2 1.6 1.2e-39 136.6 1.6 2.3 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KDO26411.1 - 5.2e-23 81.4 0.0 1.9e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KDO26411.1 - 8.6e-21 74.5 0.0 2.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 KDO26411.1 - 9.3e-05 22.7 0.2 0.00043 20.6 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 KDO26411.1 - 0.0014 17.6 0.1 0.0069 15.3 0.0 2.2 3 0 0 3 3 3 1 Golgi-body localisation protein domain Kinesin PF00225.23 KDO26412.1 - 7.5e-101 337.4 0.0 1.2e-100 336.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO26412.1 - 4.9e-22 78.5 0.0 1.8e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Lipoprot_C PF08794.10 KDO26412.1 - 0.041 13.9 1.1 0.33 10.9 0.1 2.5 3 0 0 3 3 3 0 Lipoprotein GNA1870 C terminal like CENP-F_leu_zip PF10473.9 KDO26412.1 - 0.044 13.8 26.4 0.024 14.7 3.9 3.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2383 PF09537.10 KDO26412.1 - 0.076 13.4 6.2 1.8 8.9 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) kleA_kleC PF17383.2 KDO26412.1 - 0.13 12.6 3.5 0.16 12.3 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Spc42p PF11544.8 KDO26412.1 - 0.14 12.2 0.6 2 8.4 0.1 2.7 2 0 0 2 2 2 0 Spindle pole body component Spc42p FlaC_arch PF05377.11 KDO26412.1 - 0.16 12.4 0.1 34 4.9 0.0 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PH_TFIIH PF08567.11 KDO26412.1 - 0.2 12.0 1.7 2.9 8.3 0.3 2.8 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain TMF_TATA_bd PF12325.8 KDO26412.1 - 1.9 8.7 20.6 1.3 9.3 2.8 4.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 KDO26412.1 - 4.1 7.8 10.1 26 5.2 0.1 4.4 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ECM11 PF15463.6 KDO26412.1 - 4.5 7.9 7.7 0.73 10.4 3.2 2.0 2 0 0 2 2 1 0 Extracellular mutant protein 11 UPF0242 PF06785.11 KDO26412.1 - 4.5 7.3 19.1 2.4 8.2 11.2 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 KDO26412.1 - 4.5 7.6 9.9 1.6 9.1 0.7 3.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 KDO26412.1 - 4.8 7.6 12.0 1.8 8.9 0.3 4.1 4 0 0 4 4 4 0 Tup N-terminal Tropomyosin PF00261.20 KDO26412.1 - 6.7 6.0 18.4 24 4.2 17.3 2.3 1 1 0 1 1 1 0 Tropomyosin YL1 PF05764.13 KDO26413.1 - 6.9 6.7 6.5 9.2 6.3 6.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1336 PF07059.12 KDO26414.1 - 4.2e-66 223.3 0.0 6.9e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 KDO26414.1 - 1e-21 77.3 0.1 2.1e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 START domain PH PF00169.29 KDO26414.1 - 4.4e-09 36.8 0.1 1.1e-08 35.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO26414.1 - 0.0059 16.9 0.2 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Polyketide_cyc2 PF10604.9 KDO26414.1 - 0.02 15.2 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport TCR PF03638.15 KDO26415.1 - 1.5e-26 92.4 50.3 1.8e-13 50.6 19.7 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Lzipper-MIP1 PF14389.6 KDO26415.1 - 0.071 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 MSL2-CXC PF16682.5 KDO26415.1 - 0.16 12.1 39.5 1.5 9.0 14.4 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Retinin_C PF04527.12 KDO26415.1 - 1.1 9.5 4.7 3.1 8.1 1.7 2.6 3 0 0 3 3 3 0 Drosophila Retinin like protein Glyco_tran_28_C PF04101.16 KDO26416.1 - 2.3e-23 83.0 0.0 2.6e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TMF_TATA_bd PF12325.8 KDO26417.1 - 0.2 11.9 29.8 1.3 9.2 5.0 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding tRNA-synt_2c PF01411.19 KDO26418.1 - 1.1e-205 684.3 0.0 1.4e-205 684.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KDO26418.1 - 4.1e-14 52.4 0.0 8.9e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KDO26418.1 - 1.6e-08 35.1 5.9 6.2e-08 33.2 5.9 2.1 1 0 0 1 1 1 1 DHHA1 domain RPA_interact_N PF14766.6 KDO26419.1 - 0.0001 21.8 1.4 0.0002 20.9 1.4 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal DUF1178 PF06676.11 KDO26419.1 - 0.00042 20.7 0.2 0.019 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1178) DUF438 PF04282.13 KDO26419.1 - 0.24 11.4 1.7 11 6.1 0.0 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF438) Mito_carr PF00153.27 KDO26420.1 - 3.1e-25 87.9 0.7 2.9e-10 39.9 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein OB_NTP_bind PF07717.16 KDO26421.1 - 3.1e-17 62.7 0.0 5.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KDO26422.1 - 6.2e-19 68.3 0.1 6.2e-19 68.3 0.1 3.4 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KDO26422.1 - 7.1e-11 42.4 1.3 1.1e-09 38.6 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO26422.1 - 1.3e-06 28.3 0.0 3.5e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO26422.1 - 0.00014 22.1 2.8 0.00041 20.6 0.0 3.0 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 KDO26422.1 - 0.00079 18.6 0.0 0.00079 18.6 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.22 KDO26422.1 - 0.041 13.5 0.3 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 KDO26422.1 - 0.05 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KDO26422.1 - 0.32 11.1 2.4 0.63 10.2 0.0 2.7 3 1 1 4 4 4 0 AAA domain AAA_23 PF13476.6 KDO26422.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.0 3 1 1 4 4 4 0 AAA domain WAC_Acf1_DNA_bd PF10537.9 KDO26422.1 - 6.9 7.3 7.3 2.6 8.6 0.0 3.4 4 0 0 4 4 4 0 ATP-utilising chromatin assembly and remodelling N-terminal Pescadillo_N PF06732.11 KDO26423.1 - 2e-114 381.7 3.1 2e-114 381.7 3.1 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KDO26423.1 - 1.3e-09 38.3 0.0 3.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PEX11 PF05648.14 KDO26423.1 - 0.0032 17.0 0.1 0.03 13.8 0.0 2.6 2 1 1 3 3 3 1 Peroxisomal biogenesis factor 11 (PEX11) Clc-like PF07062.12 KDO26425.1 - 0.15 11.5 16.0 18 4.7 16.0 2.7 1 1 0 1 1 1 0 Clc-like DUF4293 PF14126.6 KDO26425.1 - 0.37 11.0 8.7 0.22 11.8 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) PMT PF02366.18 KDO26425.1 - 5.6 6.5 16.3 0.21 11.1 10.4 1.5 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF485 PF04341.12 KDO26426.1 - 5.2 7.1 8.6 4.6 7.2 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Adeno_E3_14_5 PF04834.12 KDO26427.1 - 0.08 13.5 1.8 3.2 8.4 0.3 2.4 2 0 0 2 2 2 0 Early E3 14.5 kDa protein Claudin_2 PF13903.6 KDO26427.1 - 0.1 12.3 11.5 14 5.4 11.5 2.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane PF01061.24 KDO26428.1 - 9.5e-69 231.0 78.8 6.9e-38 130.2 33.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO26428.1 - 2.4e-32 112.3 0.2 1.3e-16 61.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO26428.1 - 3.1e-06 27.2 0.4 0.12 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO26428.1 - 1.7e-05 24.8 0.2 0.0056 16.6 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase AAA_16 PF13191.6 KDO26428.1 - 1.8e-05 25.2 0.1 0.11 12.8 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO26428.1 - 2.5e-05 23.9 3.6 0.021 14.6 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 KDO26428.1 - 9e-05 22.3 4.0 0.049 13.5 0.1 3.4 2 0 0 2 2 2 2 CDR ABC transporter MMR_HSR1 PF01926.23 KDO26428.1 - 0.00027 21.0 0.9 0.44 10.6 0.3 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO26428.1 - 0.0036 17.6 0.4 0.69 10.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KDO26428.1 - 0.0049 16.3 2.0 0.2 11.0 0.1 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain PolyG_pol PF01518.16 KDO26428.1 - 0.011 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma NS protein AAA_25 PF13481.6 KDO26428.1 - 0.012 15.2 1.1 0.26 10.8 0.3 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO26428.1 - 0.017 15.5 0.6 19 5.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ABC2_membrane_3 PF12698.7 KDO26428.1 - 0.025 13.7 66.9 0.019 14.1 23.9 3.3 2 1 0 2 2 2 0 ABC-2 family transporter protein Zeta_toxin PF06414.12 KDO26428.1 - 0.027 13.7 0.9 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KDO26428.1 - 0.034 14.2 0.6 1.2 9.1 0.3 2.3 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 KDO26428.1 - 0.046 14.0 0.4 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO26428.1 - 0.05 14.2 0.1 4.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO26428.1 - 0.22 11.2 0.4 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO26428.1 - 0.25 11.8 0.8 1.2 9.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO26428.1 - 0.27 11.5 0.7 37 4.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KDO26428.1 - 0.29 10.7 0.6 16 5.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KDO26428.1 - 0.41 10.4 1.5 3.5 7.4 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane PF01061.24 KDO26429.1 - 2.7e-70 236.1 77.9 1.4e-38 132.5 32.0 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO26429.1 - 1.1e-31 110.2 0.1 4.6e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KDO26429.1 - 9.7e-06 25.2 3.3 0.02 14.6 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KDO26429.1 - 2.1e-05 23.8 59.3 0.00044 19.5 19.2 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO26429.1 - 2.2e-05 24.5 0.7 0.24 11.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO26429.1 - 2.4e-05 24.3 0.3 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KDO26429.1 - 4.4e-05 23.9 0.1 0.26 11.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KDO26429.1 - 5.2e-05 22.8 0.1 0.018 14.5 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO26429.1 - 0.00042 20.4 0.4 0.97 9.5 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KDO26429.1 - 0.0085 15.4 0.1 3.9 6.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KDO26429.1 - 0.0098 16.2 0.1 0.84 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO26429.1 - 0.01 15.4 1.4 0.19 11.3 0.3 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KDO26429.1 - 0.019 15.4 0.2 0.76 10.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO26429.1 - 0.12 12.1 0.2 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO26429.1 - 0.13 12.6 0.4 31 5.0 0.2 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KDO26429.1 - 0.15 12.3 0.7 22 5.3 0.2 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KDO26429.1 - 0.16 12.2 1.0 2.7 8.2 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO26429.1 - 0.19 12.2 0.3 16 5.9 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KDO26429.1 - 0.31 11.1 1.9 16 5.5 0.5 2.5 2 0 0 2 2 2 0 Dynamin family ABC2_membrane PF01061.24 KDO26430.1 - 1e-56 191.7 78.1 1.1e-33 116.4 30.6 3.8 3 1 1 4 4 3 3 ABC-2 type transporter ABC_tran PF00005.27 KDO26430.1 - 1.5e-31 109.8 0.0 1.6e-16 61.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KDO26430.1 - 1.2e-07 31.6 7.6 0.00011 22.0 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter AAA_21 PF13304.6 KDO26430.1 - 2.1e-06 27.8 0.4 0.24 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO26430.1 - 4.2e-06 26.4 2.6 0.0082 15.9 0.3 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO26430.1 - 1.4e-05 25.6 0.2 0.12 12.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO26430.1 - 1.5e-05 25.0 0.6 0.0094 15.9 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KDO26430.1 - 4.5e-05 22.7 20.4 4.5e-05 22.7 20.4 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KDO26430.1 - 0.00018 21.0 0.2 0.0075 15.7 0.1 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO26430.1 - 0.00037 20.6 0.2 0.38 10.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO26430.1 - 0.00054 20.2 0.1 1.6 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KDO26430.1 - 0.0093 15.6 1.2 0.24 10.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KDO26430.1 - 0.085 13.4 0.9 0.49 10.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO26430.1 - 0.18 11.1 2.9 9.1 5.5 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KDO26430.1 - 0.18 12.0 2.2 16 5.7 0.4 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KDO26430.1 - 0.45 10.6 2.0 2.8 8.0 0.2 2.5 2 0 0 2 2 2 0 Dynamin family Spore_YhaL PF14147.6 KDO26430.1 - 0.87 9.3 2.8 4.5 7.0 0.8 2.8 2 0 0 2 2 2 0 Sporulation protein YhaL Kelch_4 PF13418.6 KDO26431.1 - 1e-22 79.9 21.4 2.2e-05 24.3 0.1 7.9 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO26431.1 - 4.9e-20 71.1 28.4 3.6e-05 23.6 2.6 7.6 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KDO26431.1 - 2.8e-15 56.2 27.1 0.0014 18.9 0.1 8.2 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO26431.1 - 6.2e-14 51.7 23.6 1.3e-05 25.3 0.1 7.8 7 1 0 7 7 7 4 Kelch motif EGF_2 PF07974.13 KDO26431.1 - 3.7e-10 40.0 57.7 0.00022 21.5 10.8 5.2 4 0 0 4 4 4 4 EGF-like domain Kelch_1 PF01344.25 KDO26431.1 - 1.1e-07 31.4 32.1 7.3e-05 22.3 0.1 7.7 7 2 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KDO26431.1 - 9.4e-07 28.6 17.4 0.0051 16.8 0.1 6.3 5 2 0 5 5 5 2 Kelch motif EGF_Tenascin PF18720.1 KDO26431.1 - 0.0025 17.8 9.7 0.0025 17.8 9.7 5.6 5 0 0 5 5 5 3 Tenascin EGF domain TPR_2 PF07719.17 KDO26432.1 - 1.3e-26 90.5 17.1 0.033 14.3 0.0 11.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26432.1 - 1.2e-24 85.1 26.9 0.00018 21.2 0.0 12.1 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26432.1 - 7.6e-21 73.3 4.4 0.42 11.4 0.0 11.7 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26432.1 - 2.5e-19 69.5 5.7 0.0018 18.8 0.0 8.3 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26432.1 - 2.6e-19 67.7 8.5 0.0037 17.2 0.0 9.5 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26432.1 - 4.3e-19 68.6 14.7 4e-05 23.8 0.0 9.6 6 2 5 11 11 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO26432.1 - 1.1e-13 51.2 21.0 0.0013 18.9 1.6 6.7 5 3 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KDO26432.1 - 1.2e-13 50.7 0.0 1.4 10.0 0.0 8.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26432.1 - 1.2e-13 51.4 0.0 0.016 15.9 0.1 7.6 7 2 3 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26432.1 - 1.7e-13 49.6 14.8 0.2 12.0 0.0 11.3 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26432.1 - 3.9e-07 29.7 19.2 0.0076 15.9 0.0 7.7 9 1 1 10 10 8 2 TPR repeat TPR_9 PF13371.6 KDO26432.1 - 1.1e-06 28.7 0.0 0.46 10.7 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 KDO26432.1 - 4.7e-06 26.5 6.4 2.3e-05 24.2 0.4 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KDO26432.1 - 6.3e-05 23.0 1.3 45 4.2 0.0 7.5 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 KDO26432.1 - 0.00023 20.9 8.6 0.0043 16.8 0.4 4.8 3 2 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF3808 PF10300.9 KDO26432.1 - 0.00058 18.7 1.7 0.012 14.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 KDO26432.1 - 0.00061 19.3 2.7 1.7 7.9 0.0 4.7 4 2 2 6 6 6 1 MalT-like TPR region TPR_17 PF13431.6 KDO26432.1 - 0.0021 18.3 11.5 1.3 9.6 0.2 6.8 7 0 0 7 7 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KDO26432.1 - 0.0046 16.6 1.3 1.3 8.7 0.1 4.1 5 1 0 5 5 4 1 Bacterial type III secretion protein (HrpB1_HrpK) SRP_TPR_like PF17004.5 KDO26432.1 - 0.023 14.7 11.7 0.23 11.5 0.2 5.0 4 2 1 5 5 5 0 Putative TPR-like repeat TPR_20 PF14561.6 KDO26432.1 - 0.066 13.6 0.8 12 6.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 KDO26432.1 - 0.11 13.1 1.5 8.8 7.0 0.0 4.8 6 0 0 6 6 4 0 Domain of unknown function (DUF4810) TPR_10 PF13374.6 KDO26432.1 - 2.3 8.2 23.5 3 7.8 0.1 8.4 11 0 0 11 11 10 0 Tetratricopeptide repeat PPR PF01535.20 KDO26432.1 - 3 8.3 10.9 98 3.5 0.1 6.4 8 0 0 8 8 6 0 PPR repeat EF-hand_7 PF13499.6 KDO26433.1 - 1.5e-50 169.5 5.3 1e-14 54.7 0.1 6.8 7 0 0 7 7 6 5 EF-hand domain pair EF-hand_1 PF00036.32 KDO26433.1 - 2.3e-42 139.4 2.9 3.8e-05 22.9 0.0 8.8 8 0 0 8 8 8 8 EF hand EF-hand_6 PF13405.6 KDO26433.1 - 2e-35 117.6 8.6 1.7e-05 24.4 0.0 9.3 9 0 0 9 9 9 8 EF-hand domain EF-hand_5 PF13202.6 KDO26433.1 - 1e-27 94.3 7.1 0.00029 20.2 0.0 8.4 8 0 0 8 8 8 6 EF hand WW PF00397.26 KDO26433.1 - 1.8e-25 88.7 14.8 3.6e-11 42.9 1.5 4.6 4 0 0 4 4 4 4 WW domain EF-hand_8 PF13833.6 KDO26433.1 - 6.9e-25 86.7 10.4 2e-08 34.0 0.0 7.2 6 2 2 8 8 8 5 EF-hand domain pair Ank_2 PF12796.7 KDO26433.1 - 2.5e-16 60.0 2.4 2.3e-05 24.9 0.6 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) SPARC_Ca_bdg PF10591.9 KDO26433.1 - 3.7e-11 43.3 4.5 0.01 16.2 0.1 5.0 4 1 1 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO26433.1 - 8.7e-09 35.6 0.3 0.13 12.6 0.0 4.8 5 0 0 5 5 4 2 EF-hand domain EF-hand_10 PF14788.6 KDO26433.1 - 2.8e-07 30.3 0.1 0.11 12.4 0.0 4.7 4 0 0 4 4 4 2 EF hand Ank_3 PF13606.6 KDO26433.1 - 7.3e-07 29.0 18.7 0.55 11.0 0.1 8.9 9 0 0 9 9 8 2 Ankyrin repeat Ank_4 PF13637.6 KDO26433.1 - 2.9e-05 24.5 4.5 0.057 14.0 0.2 5.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO26433.1 - 3.2e-05 24.1 9.5 0.11 12.9 0.0 5.8 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO26433.1 - 3.7e-05 24.0 21.1 4.9 7.8 0.1 8.5 8 0 0 8 8 8 1 Ankyrin repeat AsnC_trans_reg PF01037.21 KDO26433.1 - 0.091 12.7 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Chordopox_A30L PF06015.12 KDO26433.1 - 0.17 11.7 0.5 17 5.3 0.0 2.7 2 0 0 2 2 2 0 Chordopoxvirus A30L protein UPF0154 PF03672.13 KDO26433.1 - 0.17 11.9 0.0 29 4.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PDEase_I PF00233.19 KDO26434.1 - 1e-68 231.6 1.9 2.9e-68 230.1 1.9 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CPP1-like PF11833.8 KDO26435.1 - 0.17 11.5 0.8 0.18 11.4 0.8 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Protocadherin PF08374.11 KDO26436.1 - 0.61 10.0 5.5 0.93 9.4 5.5 1.3 1 0 0 1 1 1 0 Protocadherin Peptidase_S49_N PF08496.10 KDO26436.1 - 4.7 7.3 9.8 18 5.4 9.9 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PLAC8 PF04749.17 KDO26437.1 - 9.1e-19 68.3 14.7 1.5e-18 67.6 14.7 1.3 1 0 0 1 1 1 1 PLAC8 family MTABC_N PF16185.5 KDO26437.1 - 0.049 13.1 0.3 0.049 13.1 0.3 1.8 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region PLAC8 PF04749.17 KDO26438.1 - 1.7e-16 61.0 16.5 1.7e-16 61.0 16.5 2.9 2 0 0 2 2 2 1 PLAC8 family DUF1736 PF08409.11 KDO26438.1 - 7.9e-08 32.2 0.6 2e-07 30.9 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_9 PF13371.6 KDO26438.1 - 0.001 19.2 2.3 0.0029 17.7 1.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26438.1 - 0.0062 17.0 1.3 0.013 15.9 1.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26438.1 - 0.07 12.8 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KDO26438.1 - 0.072 13.2 0.6 39 4.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26438.1 - 0.089 13.0 0.2 4.3 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26438.1 - 0.12 12.3 0.4 12 5.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyl_transf_3 PF01757.22 KDO26438.1 - 1.3 8.0 26.6 0.026 13.6 17.5 2.5 2 1 0 2 2 2 0 Acyltransferase family TPR_16 PF13432.6 KDO26438.1 - 4 8.2 6.8 0.46 11.2 1.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1336 PF07059.12 KDO26439.1 - 2.3e-65 220.8 0.0 5.5e-65 219.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 KDO26439.1 - 8.9e-14 51.4 0.2 1.5e-13 50.7 0.2 1.2 1 0 0 1 1 1 1 START domain PH PF00169.29 KDO26439.1 - 9.7e-08 32.5 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO26439.1 - 0.002 18.4 0.0 0.019 15.2 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_2 PF12796.7 KDO26442.1 - 7.9e-23 80.9 5.6 1.1e-12 48.3 0.5 2.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26442.1 - 2.4e-20 72.6 5.2 4.4e-08 33.5 0.3 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26442.1 - 3e-20 70.2 5.5 4.4e-05 23.5 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO26442.1 - 3e-18 65.3 10.5 0.00014 22.1 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KDO26442.1 - 1.8e-17 63.2 9.7 2.4e-06 27.7 0.2 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DnaJ PF00226.31 KDO26444.1 - 1.3e-17 63.7 0.3 2.8e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4914 PF16260.5 KDO26445.1 - 0.11 10.6 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) NUDIX PF00293.28 KDO26446.1 - 5.6e-13 49.1 0.0 8.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ricin_B_lectin PF00652.22 KDO26447.1 - 1.1e-05 25.6 1.0 5.9e-05 23.3 0.7 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain PE PF00934.20 KDO26447.1 - 0.075 13.4 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 PE family DnaJ PF00226.31 KDO26448.1 - 6.9e-22 77.3 0.9 1.5e-21 76.3 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Trigger_C PF05698.14 KDO26448.1 - 0.00094 19.2 0.3 0.004 17.2 0.1 1.8 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus Pkinase PF00069.25 KDO26449.1 - 0.00032 20.1 0.0 0.00089 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26449.1 - 0.054 12.8 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF1943 PF09172.11 KDO26450.1 - 0.093 12.0 2.4 0.11 11.8 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) FAM76 PF16046.5 KDO26450.1 - 1.1 8.5 9.3 1.2 8.5 9.3 1.0 1 0 0 1 1 1 0 FAM76 protein DUF5523 PF17661.1 KDO26450.1 - 2.4 7.8 14.3 3.2 7.4 14.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC45 PF02724.14 KDO26450.1 - 3 6.0 11.3 3.2 5.9 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GET2 PF08690.10 KDO26450.1 - 3.3 7.3 9.8 3.3 7.3 9.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 CDC27 PF09507.10 KDO26450.1 - 3.7 6.8 19.8 4 6.7 19.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRN3 PF05327.11 KDO26450.1 - 4.4 5.7 10.5 4.8 5.6 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 XAP5 PF04921.14 KDO26450.1 - 8.6 6.1 11.3 9.9 5.9 11.3 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator cNMP_binding PF00027.29 KDO26451.1 - 6.1e-30 103.1 0.2 1.5e-17 63.4 0.0 3.3 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RGS PF00615.19 KDO26451.1 - 1.6e-17 63.9 2.7 2.4e-17 63.3 0.4 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain Methyltrans_Mon PF14314.6 KDO26451.1 - 0.025 12.6 0.0 0.037 12.1 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase RGS PF00615.19 KDO26452.1 - 1.7e-14 54.1 0.0 2.1e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain cNMP_binding PF00027.29 KDO26452.1 - 4.9e-13 49.0 0.0 7.3e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PCNA_C PF02747.15 KDO26452.1 - 0.004 17.3 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Dynamin_M PF01031.20 KDO26453.1 - 0.15 11.2 8.3 0.075 12.2 5.6 1.7 2 0 0 2 2 2 0 Dynamin central region P4Ha_N PF08336.11 KDO26453.1 - 0.85 9.6 4.9 7.4 6.6 0.0 3.3 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region zf-C4H2 PF10146.9 KDO26453.1 - 2.2 8.6 11.3 3.1 8.0 8.5 2.3 2 1 0 2 2 2 0 Zinc finger-containing protein Med9 PF07544.13 KDO26453.1 - 3.4 7.8 8.2 2 8.6 1.5 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PKD_channel PF08016.12 KDO26454.1 - 1.5e-06 27.2 13.9 1.5e-06 27.2 13.9 2.2 2 1 0 2 2 2 1 Polycystin cation channel SpoU_methylase PF00588.19 KDO26455.1 - 2.2e-18 66.8 0.0 2.7e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family AA_permease_2 PF13520.6 KDO26456.1 - 3.7e-26 91.9 26.3 1.2e-15 57.3 10.3 2.1 1 1 1 2 2 2 2 Amino acid permease Mannitol_dh_C PF08125.13 KDO26457.1 - 2.1e-05 24.1 0.3 0.00039 20.0 0.3 2.2 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Monellin PF09200.10 KDO26459.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Monellin Metallophos PF00149.28 KDO26460.1 - 1.1e-06 29.3 4.8 1.9e-06 28.5 1.3 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Hid1 PF12722.7 KDO26463.1 - 1.2e-192 642.2 1.2 4.8e-162 541.0 1.2 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KDO26463.1 - 8.9e-182 605.8 0.5 1e-181 605.6 0.5 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SDF PF00375.18 KDO26464.1 - 1.9e-66 224.7 36.6 1.4e-65 221.8 36.6 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family FANCI_S2 PF14676.6 KDO26465.1 - 1.5e-24 87.1 0.2 1.5e-24 87.1 0.2 2.6 2 1 0 2 2 2 1 FANCI solenoid 2 FANCI_S4 PF14678.6 KDO26465.1 - 1.7e-23 83.1 0.6 2.5e-22 79.2 0.6 2.4 1 1 0 1 1 1 1 FANCI solenoid 4 FANCI_S1 PF14675.6 KDO26465.1 - 1.1e-10 41.5 0.1 6.7e-10 38.9 0.0 2.4 2 1 0 2 2 2 1 FANCI solenoid 1 FANCI_HD2 PF14680.6 KDO26465.1 - 5.8e-08 32.3 0.2 0.00031 20.1 0.0 3.7 3 0 0 3 3 3 1 FANCI helical domain 2 IFN-gamma PF00714.17 KDO26465.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Interferon gamma Drc1-Sld2 PF11719.8 KDO26465.1 - 3.8 7.0 7.2 6.8 6.1 7.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein NOA36 PF06524.12 KDO26465.1 - 4.9 6.4 14.8 9.7 5.4 14.8 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KDO26465.1 - 6.3 4.9 14.6 14 3.7 14.6 1.5 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KDO26465.1 - 9.8 5.7 11.4 19 4.7 11.4 1.4 1 0 0 1 1 1 0 PPP4R2 Astacin PF01400.24 KDO26466.1 - 3e-15 56.4 0.7 2.8e-14 53.2 0.7 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KDO26466.1 - 0.043 14.3 1.0 0.087 13.3 1.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KDO26466.1 - 0.6 8.7 3.3 0.92 8.0 3.3 1.2 1 0 0 1 1 1 0 Putative peptidase family PDEase_I PF00233.19 KDO26467.1 - 2.1e-41 142.2 1.5 2.1e-41 142.2 1.5 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 KDO26468.1 - 6.3e-12 45.5 13.9 1.7e-11 44.1 13.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO26468.1 - 4.7e-10 39.2 1.9 5.8e-10 38.9 0.4 1.8 2 0 0 2 2 2 1 START domain FYVE_2 PF02318.16 KDO26468.1 - 6.2e-06 26.4 3.9 2e-05 24.8 3.9 2.0 1 0 0 1 1 1 1 FYVE-type zinc finger IP_trans PF02121.18 KDO26469.1 - 9.5e-64 215.3 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein adh_short PF00106.25 KDO26470.1 - 3.9e-17 62.3 0.4 8.6e-17 61.2 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO26470.1 - 9.4e-10 38.4 0.8 5.8e-09 35.8 0.8 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase IP_trans PF02121.18 KDO26471.1 - 5.8e-87 291.4 0.0 6.7e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Nramp PF01566.18 KDO26472.1 - 5.4e-88 295.4 14.3 5.4e-88 295.4 14.3 1.8 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein Exo_endo_phos PF03372.23 KDO26473.1 - 2.4e-10 40.4 0.1 4.8e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KDO26473.1 - 2.9e-08 33.7 0.0 1.1e-06 28.5 0.0 2.5 1 1 0 1 1 1 1 RhoGAP domain MTS PF05175.14 KDO26474.1 - 3.1e-10 39.9 0.0 2.3e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KDO26474.1 - 6.5e-05 22.5 0.0 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO26474.1 - 0.0011 19.6 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KDO26474.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase UPF0020 PF01170.18 KDO26474.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KDO26474.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_C26 PF07722.13 KDO26475.1 - 4.9e-18 65.7 0.0 2.1e-16 60.3 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KDO26475.1 - 1.6e-09 37.8 0.0 2.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I zf-RING_UBOX PF13445.6 KDO26476.1 - 1.8e-09 37.5 3.2 6.9e-08 32.4 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KDO26476.1 - 2.7e-08 34.0 4.0 5.8e-08 32.9 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO26476.1 - 8.4e-07 28.8 2.9 1.6e-06 27.9 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO26476.1 - 1.2e-06 28.3 1.5 2.2e-06 27.4 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO26476.1 - 1.8e-06 28.0 3.7 3.5e-05 23.9 4.6 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KDO26476.1 - 5.3e-06 26.2 3.9 1.1e-05 25.2 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO26476.1 - 3.8e-05 23.5 2.4 7.2e-05 22.7 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KDO26476.1 - 0.00022 21.0 1.1 0.00037 20.2 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KDO26476.1 - 0.002 17.8 3.2 0.0028 17.3 0.5 2.4 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_6 PF14835.6 KDO26476.1 - 0.0025 17.7 1.2 0.0044 16.8 1.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KDO26476.1 - 0.0048 16.7 3.8 0.0088 15.9 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO26476.1 - 0.027 14.8 2.5 0.21 11.9 2.6 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO26476.1 - 0.052 13.6 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2929 PF11151.8 KDO26476.1 - 0.068 13.5 1.9 0.24 11.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) SDF PF00375.18 KDO26477.1 - 2.2e-72 244.2 30.8 4.5e-72 243.2 30.8 1.4 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Ion_trans PF00520.31 KDO26478.1 - 2.8e-28 98.8 33.5 2.2e-24 86.0 15.5 2.2 2 0 0 2 2 2 2 Ion transport protein ABC_tran PF00005.27 KDO26479.1 - 2.3e-48 164.2 0.0 2.6e-28 99.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO26479.1 - 7.6e-40 137.3 24.7 9.6e-26 91.0 8.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO26479.1 - 3.9e-06 26.5 5.5 0.074 12.5 0.1 4.1 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO26479.1 - 4.6e-06 27.1 3.3 0.075 13.4 0.5 3.2 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO26479.1 - 1.3e-05 25.2 0.1 0.063 13.4 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KDO26479.1 - 2e-05 24.6 0.1 0.73 9.6 0.0 4.0 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO26479.1 - 0.00044 20.5 0.4 1.8 8.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KDO26479.1 - 0.00084 19.3 0.3 0.67 9.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO26479.1 - 0.0017 18.0 0.3 2.6 7.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KDO26479.1 - 0.0042 16.8 1.2 2.7 7.7 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_23 PF13476.6 KDO26479.1 - 0.016 15.7 0.0 4.4 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KDO26479.1 - 0.021 14.9 0.6 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KDO26479.1 - 0.024 15.2 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO26479.1 - 0.026 13.7 0.3 2.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KDO26479.1 - 0.15 12.0 0.3 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KDO26479.1 - 0.16 12.4 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KDO26479.1 - 0.2 11.1 0.3 20 4.6 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KDO26479.1 - 0.22 10.9 1.1 28 3.9 0.2 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.17 KDO26479.1 - 0.34 11.0 1.4 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 KDO26479.1 - 0.52 10.1 2.1 19 5.0 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KDO26479.1 - 0.62 9.6 3.8 17 4.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain Aa_trans PF01490.18 KDO26480.1 - 1.1e-34 119.9 28.7 1.5e-34 119.4 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO26481.1 - 9e-40 136.6 25.2 1.2e-39 136.3 25.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO26482.1 - 3.7e-37 128.0 29.3 4.7e-37 127.7 29.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26482.1 - 1.8e-05 24.0 13.6 1.8e-05 24.0 13.6 3.2 2 2 1 3 3 3 1 Tryptophan/tyrosine permease family OrsD PF12013.8 KDO26483.1 - 5.7e-05 23.5 0.1 9.6e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DUF295 PF03478.18 KDO26483.1 - 0.034 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Cellulase PF00150.18 KDO26484.1 - 1.2e-11 44.5 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NTP_transf_9 PF04248.12 KDO26484.1 - 0.1 12.5 1.4 4.4 7.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF427) XPG_I PF00867.18 KDO26486.1 - 2.5e-21 75.9 0.0 4.6e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KDO26486.1 - 1.9e-14 54.0 0.0 4.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KDO26486.1 - 0.0049 16.4 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing CBAH PF02275.18 KDO26487.1 - 6.9e-32 111.4 0.0 2e-30 106.6 0.0 2.2 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF1110 PF06533.12 KDO26487.1 - 0.0048 16.9 0.1 0.008 16.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1110) UPF0016 PF01169.19 KDO26487.1 - 0.013 15.8 1.5 0.033 14.5 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 CBAH PF02275.18 KDO26488.1 - 4.7e-30 105.3 0.0 1.4e-27 97.2 0.0 2.2 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family CBAH PF02275.18 KDO26489.1 - 4.1e-29 102.2 0.0 1.4e-24 87.3 0.0 2.1 1 1 1 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF2613 PF11021.8 KDO26489.1 - 0.55 10.4 4.4 0.27 11.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Metallophos PF00149.28 KDO26490.1 - 1.7e-06 28.7 0.0 3.3e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.22 KDO26491.1 - 2.2e-79 267.4 0.0 2.9e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 KDO26492.1 - 0.00021 21.8 0.2 0.00065 20.3 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KDO26493.1 - 5.3e-07 30.3 0.0 1.4e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CwsA PF10814.8 KDO26493.1 - 0.047 13.9 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Endomucin PF07010.12 KDO26494.1 - 0.11 12.4 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Endomucin Seryl_tRNA_N PF02403.22 KDO26495.1 - 3.9 7.7 22.2 0.84 9.9 1.5 4.1 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Metallophos PF00149.28 KDO26496.1 - 3.9e-12 47.1 0.0 6.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO26496.1 - 0.0008 19.6 0.0 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF2786 PF10979.8 KDO26496.1 - 0.032 14.2 0.2 0.065 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Peptidase_U57 PF05582.12 KDO26496.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Metallophos PF00149.28 KDO26497.1 - 1.1e-11 45.6 0.0 1.8e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_U57 PF05582.12 KDO26497.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Metallophos PF00149.28 KDO26498.1 - 3e-10 40.9 2.3 7.7e-10 39.6 2.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO26498.1 - 1.5e-05 25.3 0.4 0.27 11.4 0.0 3.1 3 0 0 3 3 3 3 Calcineurin-like phosphoesterase superfamily domain PI3_PI4_kinase PF00454.27 KDO26499.1 - 1.1e-20 74.5 0.0 1.9e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase LRR_9 PF14580.6 KDO26500.1 - 4.1e-18 65.5 1.1 5e-16 58.7 0.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KDO26500.1 - 2.1e-10 40.6 8.7 0.00071 19.9 0.2 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26500.1 - 0.18 11.6 11.2 0.78 9.6 4.1 2.8 1 1 2 3 3 3 0 Leucine rich repeat Dynamin_N PF00350.23 KDO26501.1 - 1.2e-33 116.6 0.0 2.4e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KDO26501.1 - 3.7e-33 115.0 0.0 5e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KDO26501.1 - 9.1e-07 29.0 0.1 1.9e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KDO26501.1 - 1.4e-06 28.3 0.0 5.7e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SbcD_C PF12320.8 KDO26501.1 - 0.0086 16.4 0.8 31 5.0 0.0 3.8 3 0 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain ABC_tran PF00005.27 KDO26501.1 - 0.059 13.9 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KDO26501.1 - 0.14 11.9 0.2 0.33 10.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain adh_short PF00106.25 KDO26502.1 - 3.2e-29 101.8 0.0 1.2e-25 90.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO26502.1 - 3.1e-18 66.2 0.2 1.1e-17 64.4 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO26502.1 - 4.5e-10 39.7 0.1 6.6e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO26502.1 - 0.001 18.6 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KDO26502.1 - 0.058 13.2 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 KDO26502.1 - 0.1 12.8 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ubiquitin PF00240.23 KDO26503.1 - 9e-18 63.8 0.1 1.5e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KDO26503.1 - 3.2e-10 39.7 0.2 3.2e-10 39.7 0.2 3.2 4 0 0 4 4 4 1 UBA/TS-N domain STI1 PF17830.1 KDO26503.1 - 1.3e-06 28.2 59.6 0.00012 22.0 8.3 5.1 3 1 1 4 4 4 2 STI1 domain Rad60-SLD PF11976.8 KDO26503.1 - 1.1e-05 25.1 0.1 1.8e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DEC-1_N PF04625.13 KDO26503.1 - 0.0014 17.7 11.7 0.0014 17.7 11.7 3.5 2 1 2 4 4 4 1 DEC-1 protein, N-terminal region TBK1_ULD PF18396.1 KDO26503.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 KDO26503.1 - 0.022 14.8 0.2 2.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KDO26503.1 - 0.092 13.3 0.0 0.31 11.6 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain RasGEF_N_2 PF14663.6 KDO26503.1 - 1.4 9.3 5.2 12 6.3 0.3 3.6 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SIL1 PF16782.5 KDO26503.1 - 1.7 7.8 3.0 0.91 8.7 0.9 1.5 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 Sec62 PF03839.16 KDO26504.1 - 8.4e-16 58.1 0.4 1.4e-15 57.4 0.0 1.5 2 0 0 2 2 2 1 Translocation protein Sec62 DUF2632 PF10943.8 KDO26504.1 - 0.036 13.6 1.4 0.074 12.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) Sec62 PF03839.16 KDO26505.1 - 4.9e-15 55.6 6.1 1.1e-11 44.7 4.2 2.4 1 1 1 2 2 2 2 Translocation protein Sec62 MARVEL PF01284.23 KDO26505.1 - 0.0046 17.0 0.5 0.3 11.1 0.1 2.1 2 0 0 2 2 2 1 Membrane-associating domain Promethin PF16015.5 KDO26505.1 - 0.0059 16.5 2.5 0.015 15.2 2.5 1.7 1 1 0 1 1 1 1 Promethin DEP PF00610.21 KDO26505.1 - 0.024 14.7 0.0 0.085 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3290 PF11694.8 KDO26505.1 - 0.34 10.9 2.0 0.96 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Mannosyl_trans3 PF11051.8 KDO26506.1 - 9.7e-31 107.1 0.0 2.5e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 Mannosyltransferase putative DUF4176 PF13780.6 KDO26506.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) LCCL PF03815.19 KDO26507.1 - 3.4e-20 72.0 0.0 5.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 LCCL domain Pur_ac_phosph_N PF16656.5 KDO26507.1 - 0.016 15.7 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KDO26507.1 - 0.032 14.6 0.4 0.18 12.2 0.4 2.1 1 1 0 1 1 1 0 Fibronectin type III domain GTPase_binding PF09027.10 KDO26507.1 - 0.086 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 GTPase binding DUF1754 PF08555.10 KDO26508.1 - 0.00018 22.2 19.1 0.00027 21.6 16.8 2.1 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) UBA2_C PF16195.5 KDO26508.1 - 0.013 16.2 4.0 0.021 15.5 4.0 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus zf-PHD-like PF15446.6 KDO26508.1 - 0.047 13.3 0.4 0.063 12.9 0.4 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Rtf2 PF04641.12 KDO26508.1 - 0.13 11.7 6.9 0.15 11.4 6.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger OAD_gamma PF04277.13 KDO26508.1 - 0.2 12.3 1.5 2 9.0 0.6 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Lipase_3 PF01764.25 KDO26509.1 - 1.5e-10 41.1 0.0 3.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KDO26509.1 - 0.0014 18.2 0.6 0.041 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KDO26509.1 - 0.0062 17.2 0.0 0.028 15.0 0.0 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO26509.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Hydrolase_4 PF12146.8 KDO26510.1 - 9.5e-62 208.4 0.0 1.2e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO26510.1 - 2.2e-10 41.5 0.0 2.7e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO26510.1 - 1.3e-09 38.1 0.1 2e-07 30.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO26510.1 - 2.1e-08 33.9 0.1 0.0013 18.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KDO26510.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KDO26510.1 - 0.0016 18.3 0.0 0.0035 17.1 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Tannase PF07519.11 KDO26510.1 - 0.0031 16.5 0.0 0.0073 15.3 0.0 1.6 1 1 1 2 2 2 1 Tannase and feruloyl esterase Thioesterase PF00975.20 KDO26510.1 - 0.025 14.7 0.2 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 KDO26510.1 - 0.13 12.0 0.1 6.6 6.3 0.0 2.7 3 0 0 3 3 3 0 Serine hydrolase (FSH1) CHAP PF05257.16 KDO26511.1 - 8.3e-13 48.7 0.3 1.6e-12 47.8 0.3 1.5 1 0 0 1 1 1 1 CHAP domain FYVE PF01363.21 KDO26512.1 - 3.2e-19 68.8 11.1 4.9e-19 68.2 11.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO26512.1 - 2.8e-05 24.3 4.3 4.2e-05 23.7 4.3 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KDO26512.1 - 0.44 10.7 10.1 0.066 13.4 5.0 2.1 1 1 1 2 2 2 0 Piccolo Zn-finger C1_2 PF03107.16 KDO26512.1 - 1.9 8.9 10.5 6.9 7.1 7.1 2.3 2 0 0 2 2 2 0 C1 domain TIR_2 PF13676.6 KDO26515.1 - 2.7e-15 57.0 0.0 6.4e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain XisI PF08869.11 KDO26515.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 XisI protein adh_short PF00106.25 KDO26516.1 - 3.4e-06 26.6 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO26516.1 - 0.079 12.5 0.0 0.71 9.4 0.0 2.1 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Exo_endo_phos PF03372.23 KDO26517.1 - 1.2e-08 34.7 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_4 PF13637.6 KDO26518.1 - 3e-08 34.1 0.0 0.0018 18.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26518.1 - 0.00015 22.3 0.1 0.042 14.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO26518.1 - 0.015 15.8 0.0 13 6.7 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat PX PF00787.24 KDO26519.1 - 1.5e-08 34.6 0.1 2.2e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO26520.1 - 3e-07 30.4 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 KDO26521.1 - 1.3e-07 31.5 0.1 4.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 PX domain DUF4228 PF14009.6 KDO26521.1 - 0.049 14.0 0.8 0.08 13.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) OAM_dimer PF16554.5 KDO26521.1 - 0.066 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase ATG16 PF08614.11 KDO26522.1 - 0.0019 18.4 14.8 0.0019 18.4 14.8 4.4 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Spc29 PF17082.5 KDO26522.1 - 0.023 14.5 12.3 0.023 14.5 5.8 2.7 2 1 0 2 2 2 0 Spindle Pole Component 29 ADIP PF11559.8 KDO26522.1 - 0.18 11.9 38.7 0.042 13.9 5.2 5.1 3 2 1 5 5 5 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KDO26522.1 - 0.51 10.4 17.1 2.8 8.0 0.6 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 KDO26522.1 - 0.54 9.8 31.9 0.33 10.5 6.2 4.5 1 1 1 3 3 3 0 Intermediate filament protein Cnn_1N PF07989.11 KDO26522.1 - 0.71 10.1 6.7 4.2 7.6 0.0 4.5 3 2 2 5 5 5 0 Centrosomin N-terminal motif 1 Prp19 PF08606.11 KDO26522.1 - 2.2 8.4 12.3 3.2 7.8 0.6 4.2 3 1 0 4 4 4 0 Prp19/Pso4-like Fib_alpha PF08702.10 KDO26522.1 - 2.3 8.4 12.6 9.7 6.4 1.3 4.0 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4411 PF14367.6 KDO26522.1 - 3.5 7.5 11.5 0.22 11.4 5.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4411) FlaC_arch PF05377.11 KDO26522.1 - 3.6 8.0 7.2 51 4.4 0.0 4.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 KDO26522.1 - 3.7 8.0 16.6 7.5 7.0 0.5 4.5 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 KDO26522.1 - 8.2 5.2 36.3 0.08 11.8 8.2 3.9 1 1 3 4 4 4 0 Spc7 kinetochore protein Ank_2 PF12796.7 KDO26523.1 - 1.3e-05 25.6 4.2 0.014 16.0 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26523.1 - 0.0013 19.0 0.7 0.0073 16.6 0.1 2.7 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO26523.1 - 0.0034 17.9 6.8 0.12 13.0 0.4 4.3 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26523.1 - 0.0099 16.3 0.2 29 5.7 0.0 4.7 4 1 1 5 5 5 1 Ankyrin repeat ELO PF01151.18 KDO26525.1 - 5.1e-69 232.6 18.5 6e-69 232.3 18.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 KDO26526.1 - 5.9e-68 229.1 20.3 7e-68 228.8 20.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family TPR_1 PF00515.28 KDO26527.1 - 4e-06 26.4 0.0 0.044 13.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26527.1 - 0.0012 18.8 0.0 1.5 9.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO26527.1 - 0.0028 17.8 4.0 0.0029 17.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MBOAT_2 PF13813.6 KDO26527.1 - 0.062 13.6 0.5 0.17 12.2 0.5 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family TPR_14 PF13428.6 KDO26527.1 - 0.35 11.8 4.9 8 7.6 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Phosphodiest PF01663.22 KDO26528.1 - 4.5e-13 49.5 1.0 3.7e-10 39.9 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KDO26528.1 - 2.5e-05 23.8 0.0 0.057 12.8 0.0 2.1 2 0 0 2 2 2 2 Sulfatase eIF-5a PF01287.20 KDO26529.1 - 8.9e-25 86.6 0.0 1.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KDO26529.1 - 6.9e-05 22.8 0.1 9.7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TauD PF02668.16 KDO26530.1 - 3.6e-39 135.2 0.5 4.7e-39 134.8 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KDO26530.1 - 1.5e-06 28.7 0.1 3.7e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KDO26530.1 - 0.00033 19.9 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 CsiD zf-HC5HC2H_2 PF13832.6 KDO26531.1 - 1.6e-20 73.3 1.7 1.6e-20 73.3 1.7 3.2 3 1 1 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO26531.1 - 3.3e-12 46.5 0.3 3.3e-12 46.5 0.3 4.6 3 2 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KDO26531.1 - 4.9e-12 45.2 3.7 4.9e-12 45.2 3.7 5.0 5 1 0 5 5 5 1 PHD-finger PHD PF00628.29 KDO26531.1 - 2.1e-10 40.3 33.9 4.6e-10 39.2 6.1 5.4 5 1 0 5 5 5 2 PHD-finger Prok-RING_1 PF14446.6 KDO26531.1 - 6.2e-05 22.9 2.3 6.2e-05 22.9 2.3 3.6 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KDO26531.1 - 0.021 14.5 8.7 0.16 11.6 4.1 3.5 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KDO26531.1 - 0.038 13.9 0.8 0.038 13.9 0.8 4.8 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-UDP PF14569.6 KDO26531.1 - 0.48 10.6 5.9 0.56 10.4 3.7 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger T3SS_LEE_assoc PF13327.6 KDO26532.1 - 0.14 12.1 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system subunit Cofilin_ADF PF00241.20 KDO26533.1 - 2.2e-20 72.6 0.0 3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PRP38 PF03371.15 KDO26535.1 - 4.8e-56 189.3 0.1 5.5e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 PRP38 family Collagen PF01391.18 KDO26538.1 - 5.3e-33 112.6 164.8 7e-08 32.1 29.0 6.5 3 3 3 6 6 6 6 Collagen triple helix repeat (20 copies) Baculo_PEP_C PF04513.12 KDO26538.1 - 0.42 10.7 8.8 0.22 11.5 0.1 3.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DAO PF01266.24 KDO26539.1 - 8.7e-46 157.1 5.5 1e-45 156.8 5.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KDO26539.1 - 0.031 13.5 0.9 0.11 11.7 0.7 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KDO26539.1 - 0.035 13.3 0.7 0.067 12.4 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO26539.1 - 0.099 12.9 1.0 0.29 11.4 1.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KDO26539.1 - 0.4 10.5 0.8 0.68 9.8 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KDO26539.1 - 9.2 5.4 6.9 5.2 6.2 1.5 2.9 3 1 1 4 4 4 0 Thi4 family Nkap_C PF06047.11 KDO26540.1 - 3e-46 155.7 2.5 3e-46 155.7 2.5 1.8 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain Apt1 PF10351.9 KDO26540.1 - 0.00063 18.7 15.2 0.00063 18.7 15.2 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain DUF737 PF05300.11 KDO26541.1 - 8.2 6.7 9.4 37 4.6 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Na_Ca_ex PF01699.24 KDO26542.1 - 7.6e-41 139.6 35.4 2.7e-24 85.8 10.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UCH PF00443.29 KDO26543.1 - 2.9e-69 233.4 0.0 3.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KDO26543.1 - 3.6e-17 62.8 0.0 8.5e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KDO26543.1 - 1.3e-12 48.0 1.1 2.4e-05 24.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 KDO26543.1 - 4.5e-10 39.4 15.4 4.5e-10 39.4 15.4 3.2 3 0 0 3 3 3 1 MYND finger DUF4232 PF14016.6 KDO26543.1 - 0.048 13.8 0.7 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) ZF-HD_dimer PF04770.12 KDO26543.1 - 0.055 13.8 1.2 0.14 12.5 0.2 2.2 2 0 0 2 2 2 0 ZF-HD protein dimerisation region Rhodanese_C PF12368.8 KDO26543.1 - 0.49 10.8 7.7 0.2 12.0 3.7 2.4 2 0 0 2 2 2 0 Rhodanase C-terminal fn3 PF00041.21 KDO26545.1 - 0.00016 21.9 0.0 3.6 8.0 0.0 4.7 5 0 0 5 5 5 2 Fibronectin type III domain DUF2070 PF09843.9 KDO26546.1 - 0.016 13.5 1.4 0.018 13.4 1.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF996 PF06195.13 KDO26546.1 - 0.029 14.7 0.3 0.038 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Elicitin PF00964.17 KDO26546.1 - 0.039 14.1 0.9 0.06 13.4 0.9 1.3 1 0 0 1 1 1 0 Elicitin DUF4064 PF13273.6 KDO26546.1 - 0.05 13.9 0.5 0.07 13.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF5134 PF17197.4 KDO26546.1 - 1.9 8.4 12.1 3.3 7.6 12.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) S1-P1_nuclease PF02265.16 KDO26547.1 - 1.3e-33 116.9 0.0 1.7e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease S1-P1_nuclease PF02265.16 KDO26548.1 - 3.4e-36 125.4 0.0 4.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease S1-P1_nuclease PF02265.16 KDO26549.1 - 4.5e-30 105.3 0.1 5.4e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease S1-P1_nuclease PF02265.16 KDO26550.1 - 2.6e-37 129.0 0.0 3.2e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease TPR_1 PF00515.28 KDO26551.1 - 3.9e-16 58.1 5.8 0.00019 21.1 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26551.1 - 4.5e-16 58.9 18.3 2.7e-06 27.6 3.2 3.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26551.1 - 4e-14 51.5 9.0 0.0038 17.2 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26551.1 - 2.8e-13 48.9 9.7 0.0024 17.8 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26551.1 - 2.6e-09 36.6 4.6 0.023 14.9 0.4 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO26551.1 - 3.8e-08 32.9 8.8 0.0021 17.8 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO26551.1 - 8.7e-05 23.0 10.2 0.65 11.0 0.0 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO26551.1 - 0.00016 21.2 11.8 0.01 15.2 6.5 2.2 2 0 0 2 2 2 2 MalT-like TPR region MIT PF04212.18 KDO26551.1 - 0.0065 16.5 2.8 0.098 12.7 0.5 3.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KDO26551.1 - 0.0072 16.8 7.4 0.16 12.7 0.2 3.6 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26551.1 - 0.014 16.0 15.3 2.7 8.7 2.4 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26551.1 - 0.015 15.0 0.7 5.1 6.9 0.1 4.0 3 1 1 4 4 4 0 TPR repeat TPR_17 PF13431.6 KDO26551.1 - 0.022 15.1 3.2 36 5.1 0.0 4.6 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO26551.1 - 2 8.6 10.9 1.4 9.2 2.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4381 PF14316.6 KDO26552.1 - 0.087 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ubiquitin PF00240.23 KDO26553.1 - 7e-08 32.1 0.2 1.6e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO26553.1 - 0.018 14.9 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1579 PF07617.11 KDO26553.1 - 0.087 12.7 0.4 0.49 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1579) FAM209 PF15206.6 KDO26554.1 - 0.23 11.2 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 FAM209 family Na_Ca_ex PF01699.24 KDO26555.1 - 2.5e-31 108.7 34.0 1.4e-16 60.8 11.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MGC-24 PF05283.11 KDO26555.1 - 0.2 12.1 0.6 0.49 10.9 0.1 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ACOX PF01756.19 KDO26556.1 - 1.5e-31 109.4 0.5 6.3e-31 107.3 0.0 2.2 2 1 1 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KDO26556.1 - 6.6e-11 42.8 0.1 1.7e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KDO26556.1 - 5.4e-08 32.9 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SNF2_N PF00176.23 KDO26557.1 - 1.4e-49 168.7 0.0 2.6e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO26557.1 - 1.6e-17 63.8 0.1 2.7e-16 59.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO26557.1 - 0.00014 21.9 0.0 0.00054 20.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KDO26557.1 - 0.038 14.2 0.7 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain CobA_CobO_BtuR PF02572.15 KDO26557.1 - 0.17 12.1 1.2 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP VIT1 PF01988.19 KDO26557.1 - 0.31 10.9 1.1 3.8 7.3 0.2 2.9 3 0 0 3 3 3 0 VIT family DTHCT PF08070.11 KDO26557.1 - 2.1 9.1 8.3 1.3 9.8 5.7 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region TPR_2 PF07719.17 KDO26558.1 - 1.2e-18 65.7 15.3 0.0025 17.8 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26558.1 - 4.1e-15 54.9 13.9 0.007 16.1 0.7 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat CS PF04969.16 KDO26558.1 - 4.4e-06 27.6 0.0 9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_8 PF13181.6 KDO26558.1 - 5.5e-06 26.2 0.2 0.074 13.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26558.1 - 0.0002 22.0 28.1 0.00097 19.7 2.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26558.1 - 0.00022 20.8 5.5 0.13 11.9 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KDO26558.1 - 0.00027 21.2 18.0 5.8 7.3 0.1 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO26558.1 - 0.00031 21.3 21.1 0.37 11.7 0.5 5.8 5 1 1 6 6 5 3 Tetratricopeptide repeat BTAD PF03704.17 KDO26558.1 - 0.019 15.4 12.8 2.2 8.7 2.6 4.5 2 1 2 4 4 4 0 Bacterial transcriptional activator domain SAGA-Tad1 PF12767.7 KDO26558.1 - 0.021 14.5 1.2 0.03 14.0 1.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TPR_9 PF13371.6 KDO26558.1 - 0.03 14.5 16.7 0.13 12.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26558.1 - 0.22 12.1 19.6 0.47 11.0 1.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 KDO26559.1 - 0.024 15.0 8.4 0.032 14.6 8.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFMR_assoc PF16596.5 KDO26559.1 - 0.025 15.0 2.1 0.032 14.7 2.1 1.1 1 0 0 1 1 1 0 Disordered region downstream of MFMR DNA_pol_phi PF04931.13 KDO26559.1 - 0.035 12.2 4.8 0.037 12.1 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM110_C PF14160.6 KDO26559.1 - 0.048 14.7 0.4 0.064 14.3 0.4 1.1 1 0 0 1 1 1 0 Centrosome-associated C terminus Ctr PF04145.15 KDO26559.1 - 0.11 13.1 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family NOA36 PF06524.12 KDO26559.1 - 0.64 9.3 5.9 0.78 9.0 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KDO26559.1 - 3.9 7.1 13.9 5.1 6.8 13.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KDO26559.1 - 4.7 5.4 7.8 6.1 5.0 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.13 KDO26559.1 - 7.7 4.5 10.2 8.8 4.3 10.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ERM PF00769.19 KDO26560.1 - 0.0034 17.2 5.9 0.0034 17.2 5.9 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family YPEB PF14620.6 KDO26560.1 - 0.089 12.1 5.9 0.14 11.4 3.8 1.9 2 0 0 2 2 2 0 YpeB sporulation DEADboxA PF12343.8 KDO26560.1 - 0.13 12.8 1.0 0.44 11.1 1.0 1.9 1 0 0 1 1 1 0 Cold shock protein DEAD box A CENP-F_leu_zip PF10473.9 KDO26560.1 - 0.3 11.1 11.1 0.67 10.0 11.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 KDO26560.1 - 0.4 10.8 1.9 2.9 8.0 1.8 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KDO26560.1 - 0.69 8.7 8.9 1.4 7.7 8.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein LXG PF04740.12 KDO26560.1 - 0.75 9.5 5.7 1.6 8.4 5.7 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily LPP PF04728.13 KDO26560.1 - 0.77 10.2 5.0 0.77 10.2 0.8 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper EzrA PF06160.12 KDO26560.1 - 0.85 7.7 8.0 0.29 9.2 5.5 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 KDO26560.1 - 1.3 9.1 14.1 0.52 10.4 9.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein p450 PF00067.22 KDO26561.1 - 2e-63 214.8 0.0 2.6e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KDO26562.1 - 1.8e-84 284.2 0.0 2.1e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRA1 PF03208.19 KDO26563.1 - 5.3e-15 55.3 7.9 7.5e-15 54.8 7.9 1.3 1 0 0 1 1 1 1 PRA1 family protein Sre PF03125.18 KDO26563.1 - 0.75 8.9 7.6 0.24 10.5 5.0 1.5 1 1 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor ABC2_membrane_3 PF12698.7 KDO26563.1 - 2.8 7.0 10.3 3.3 6.7 10.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_assoc PF14363.6 KDO26564.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA zf-PARP PF00645.18 KDO26565.1 - 6.1e-08 33.4 1.3 2.2e-07 31.6 1.3 1.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-PARP PF00645.18 KDO26566.1 - 0.16 12.8 0.2 1.1 10.1 0.2 1.9 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DP PF08781.10 KDO26567.1 - 3.2e-31 108.1 0.3 8.5e-31 106.7 0.3 1.7 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KDO26567.1 - 5e-25 87.3 0.1 1.1e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain PBP1_TM PF14812.6 KDO26567.1 - 0.0057 17.0 3.4 0.018 15.4 3.4 1.8 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KDO26567.1 - 0.023 14.5 10.1 0.049 13.4 4.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3246 PF11596.8 KDO26567.1 - 0.065 12.7 2.5 0.12 11.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RXT2_N PF08595.11 KDO26567.1 - 0.086 12.9 1.7 0.12 12.4 0.3 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KDO26567.1 - 0.094 12.4 0.9 0.23 11.1 0.9 1.6 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KDO26567.1 - 0.22 10.8 4.3 0.36 10.1 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KDO26567.1 - 0.27 11.6 8.8 0.6 10.5 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nha1_C PF08619.10 KDO26567.1 - 1.7 7.8 11.1 1.1 8.4 9.0 1.6 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Ank_2 PF12796.7 KDO26568.1 - 7.4e-41 138.6 3.9 1.6e-10 41.4 0.0 6.5 3 3 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26568.1 - 6.8e-39 131.8 13.9 6.9e-14 52.0 0.1 8.0 7 1 1 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26568.1 - 2.2e-28 95.2 12.6 0.00043 20.5 0.0 11.3 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KDO26568.1 - 4.4e-27 93.8 21.8 2.7e-10 40.3 0.5 8.5 7 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO26568.1 - 1.3e-25 88.7 13.2 1.8e-05 25.0 0.1 11.0 11 0 0 11 11 11 4 Ankyrin repeat ADIP PF11559.8 KDO26569.1 - 0.17 11.9 0.1 0.49 10.5 0.1 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KDO26569.1 - 0.22 11.7 1.3 0.26 11.5 0.1 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) M_domain PF12938.7 KDO26571.1 - 0.2 11.4 3.0 0.24 11.1 3.0 1.1 1 0 0 1 1 1 0 M domain of GW182 Pkinase PF00069.25 KDO26572.1 - 4.8e-65 219.6 0.0 7.4e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO26572.1 - 4.9e-60 199.6 0.2 1.5e-19 69.8 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO26572.1 - 4.1e-28 98.4 0.2 2.1e-27 96.1 0.0 2.3 4 0 0 4 4 4 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO26572.1 - 0.00049 19.5 0.1 0.0028 17.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KDO26572.1 - 0.0052 16.7 0.0 0.081 12.8 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1084 PF06454.11 KDO26573.1 - 8.4e-10 38.5 3.6 1.7e-09 37.4 3.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DPM3 PF08285.11 KDO26573.1 - 1.1 9.5 9.6 0.24 11.6 0.3 3.4 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Glycos_transf_1 PF00534.20 KDO26574.1 - 3.7e-23 81.9 0.0 9.7e-23 80.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO26574.1 - 4e-20 72.6 0.0 9.5e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KDO26574.1 - 4.2e-07 30.1 0.3 1.6e-06 28.3 0.1 2.1 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KDO26574.1 - 0.002 18.6 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KDO26574.1 - 0.0046 17.3 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ints3 PF10189.9 KDO26575.1 - 7.7e-37 126.7 0.4 3.5e-36 124.6 0.4 2.0 1 1 0 1 1 1 1 Integrator complex subunit 3 HEAT_PBS PF03130.16 KDO26575.1 - 0.12 13.1 0.9 0.41 11.5 0.1 2.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 KDO26575.1 - 0.32 11.4 5.0 3.1 8.2 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats ORC6 PF05460.13 KDO26575.1 - 2.6 7.2 16.8 4.5 6.5 16.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SOG2 PF10428.9 KDO26575.1 - 5 6.2 17.2 9.5 5.3 17.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Arf PF00025.21 KDO26576.1 - 5.3e-69 231.1 0.0 6.5e-69 230.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO26576.1 - 8.5e-16 58.3 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KDO26576.1 - 3.9e-13 49.3 0.1 3e-09 36.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KDO26576.1 - 1.8e-11 43.9 0.0 2.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KDO26576.1 - 3.1e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KDO26576.1 - 1.6e-08 34.2 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO26576.1 - 2.8e-07 30.6 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO26576.1 - 0.0027 17.3 0.7 0.022 14.3 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KDO26576.1 - 0.023 15.2 0.0 0.037 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KDO26576.1 - 0.037 13.6 0.1 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KDO26576.1 - 0.074 13.1 0.2 0.34 10.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.25 KDO26577.1 - 1.2e-56 192.0 0.0 4.2e-56 190.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26577.1 - 2.5e-28 99.1 0.0 2.3e-24 86.1 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO26577.1 - 3.5e-05 22.9 0.1 5.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO26577.1 - 0.019 14.9 7.5 0.34 10.8 7.5 2.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KDO26577.1 - 0.074 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Med3 PF11593.8 KDO26577.1 - 1.1 8.3 9.4 2.3 7.3 9.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Myb_DNA-binding PF00249.31 KDO26579.1 - 8.2e-10 38.7 0.3 1.2e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO26579.1 - 0.00045 20.4 0.3 0.0008 19.6 0.3 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO26580.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SnAPC_2_like PF11035.8 KDO26580.1 - 0.025 14.7 0.8 0.028 14.6 0.8 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF1839 PF08893.10 KDO26580.1 - 0.036 13.3 0.1 0.04 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Myb_DNA-bind_6 PF13921.6 KDO26580.1 - 0.057 13.7 0.1 0.15 12.3 0.1 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Importin_rep PF18773.1 KDO26580.1 - 0.22 11.3 0.5 0.34 10.6 0.1 1.6 2 0 0 2 2 2 0 Importin 13 repeat HA PF03457.14 KDO26581.1 - 3.3e-21 75.4 17.8 3.2e-08 33.8 0.0 4.5 5 0 0 5 5 5 3 Helicase associated domain TFIIA PF03153.13 KDO26581.1 - 0.092 12.7 10.5 0.02 14.9 7.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5421 PF17458.2 KDO26581.1 - 1 8.7 10.0 1.7 8.0 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) FYVE PF01363.21 KDO26582.1 - 4.6e-11 42.7 3.4 4.6e-11 42.7 3.4 1.6 2 0 0 2 2 2 1 FYVE zinc finger Ank_5 PF13857.6 KDO26582.1 - 1.4e-06 28.4 0.6 0.00023 21.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26582.1 - 5.1e-05 23.8 0.2 9.1e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26582.1 - 0.0024 18.4 0.1 0.32 11.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26582.1 - 0.0098 16.3 0.2 4.5 8.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat PDEase_I PF00233.19 KDO26583.1 - 9.7e-76 254.6 0.8 9.7e-76 254.6 0.8 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 KDO26583.1 - 2.7e-08 33.4 6.4 4.2e-08 32.7 6.4 1.2 1 0 0 1 1 1 1 Ion transport protein Herpes_LMP1 PF05297.11 KDO26583.1 - 0.32 10.2 3.3 0.57 9.3 3.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pkinase_Tyr PF07714.17 KDO26585.1 - 1.5e-36 126.0 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26585.1 - 1.8e-35 122.6 0.0 2.8e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DEP PF00610.21 KDO26585.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kinase-like PF14531.6 KDO26585.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KDO26586.1 - 1.4e-42 145.9 0.0 2.2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26586.1 - 2.5e-42 144.9 0.0 3.6e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO26586.1 - 3.8e-07 30.1 0.1 3.1e-06 27.1 0.0 2.5 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kinase-like PF14531.6 KDO26586.1 - 0.00043 19.7 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO26586.1 - 0.0044 17.0 0.9 0.034 14.1 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KDO26587.1 - 2e-36 125.6 0.0 2.6e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26587.1 - 2.1e-31 109.3 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DEP PF00610.21 KDO26587.1 - 3e-05 24.0 0.0 5.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kinase-like PF14531.6 KDO26587.1 - 0.24 10.7 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HlyIII PF03006.20 KDO26587.1 - 0.32 10.7 10.2 0.58 9.8 10.2 1.3 1 0 0 1 1 1 0 Haemolysin-III related BaxI_1 PF12811.7 KDO26587.1 - 8.6 5.9 9.4 2.8 7.5 0.7 2.5 1 1 1 2 2 2 0 Bax inhibitor 1 like Pkinase PF00069.25 KDO26588.1 - 1.7e-43 148.9 0.0 2.5e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26588.1 - 6.3e-38 130.5 0.0 2.2e-37 128.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO26588.1 - 8.2e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2070 PF09843.9 KDO26588.1 - 7.2 4.8 16.0 13 3.9 16.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF667 PF05018.13 KDO26589.1 - 1e-22 80.8 0.0 1.2e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) GATase_6 PF13522.6 KDO26590.1 - 1.3e-15 57.7 0.1 5.1e-15 55.9 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KDO26590.1 - 5.7e-15 55.3 0.0 2.4e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KDO26590.1 - 6.4e-09 35.5 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KDO26590.1 - 1.3e-06 27.6 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Cse1 PF08506.10 KDO26591.1 - 3.4e-117 391.4 1.0 8.2e-117 390.1 0.8 1.7 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 KDO26591.1 - 1.9e-100 336.5 0.7 1.9e-100 336.5 0.7 1.9 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 KDO26591.1 - 2.9e-11 43.1 0.0 1.9e-10 40.5 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KDO26591.1 - 0.013 15.6 0.9 0.17 11.9 0.0 3.3 2 1 1 3 3 3 0 Exportin 1-like protein DUF1586 PF07625.11 KDO26591.1 - 0.13 12.4 0.8 0.37 10.9 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) SPG48 PF14764.6 KDO26591.1 - 0.65 10.5 6.0 28 5.2 0.0 5.5 5 2 1 6 6 6 0 AP-5 complex subunit, vesicle trafficking zf-RING_2 PF13639.6 KDO26592.1 - 6e-08 32.9 15.0 1.4e-07 31.7 15.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO26592.1 - 7.2e-07 29.4 10.4 1.8e-06 28.1 10.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO26592.1 - 0.003 17.4 13.6 0.0077 16.1 13.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO26592.1 - 0.0034 17.2 13.9 0.0086 15.9 13.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO26592.1 - 0.0074 16.3 9.0 0.016 15.2 9.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO26592.1 - 0.02 14.9 8.6 0.02 14.9 8.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO26592.1 - 0.02 14.7 13.8 0.045 13.6 13.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO26592.1 - 0.027 14.1 13.8 0.079 12.6 13.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KDO26592.1 - 0.035 13.8 14.0 0.035 13.8 14.0 2.3 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 KDO26592.1 - 0.052 13.5 14.6 0.37 10.8 14.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain KaiA PF07688.12 KDO26592.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 KaiA C-terminal domain NfrA_C PF13283.6 KDO26592.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Ribosomal_L7Ae PF01248.26 KDO26594.1 - 6.5e-23 80.3 1.1 1.3e-22 79.3 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KDO26594.1 - 0.011 15.7 0.3 0.16 12.0 0.3 2.1 1 1 0 1 1 1 0 RNase P subunit Pop3 Lactamase_B_6 PF16661.5 KDO26595.1 - 3.1e-55 186.6 0.0 5.5e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KDO26595.1 - 9.5e-17 61.7 7.2 9.9e-15 55.1 0.0 3.6 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KDO26595.1 - 5.8e-15 55.5 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KDO26595.1 - 1.8e-09 37.4 0.0 6.5e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KDO26595.1 - 3.1e-07 30.6 0.2 7.3e-07 29.4 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO26595.1 - 0.0051 16.3 0.8 0.018 14.6 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Fanconi_A_N PF15865.5 KDO26595.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus PCI PF01399.27 KDO26596.1 - 1e-13 51.7 0.2 7e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 PCI domain TetR_C_34 PF17929.1 KDO26596.1 - 0.027 14.5 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CSN4_RPN5_eIF3a PF18420.1 KDO26596.1 - 0.049 13.8 0.6 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain zf-trcl PF13451.6 KDO26598.1 - 6.2e-21 74.0 3.1 1.3e-20 73.0 3.1 1.6 1 0 0 1 1 1 1 Probable zinc-ribbon domain zf-CCCH PF00642.24 KDO26598.1 - 0.00073 19.4 4.7 0.0023 17.8 4.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO26598.1 - 0.0015 18.5 6.2 0.0046 17.0 6.2 1.9 1 0 0 1 1 1 1 Zinc finger domain DNA_RNApol_7kD PF03604.13 KDO26598.1 - 0.01 15.5 1.5 3.8 7.3 0.5 2.5 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit zf-CCCH_4 PF18044.1 KDO26598.1 - 0.031 14.1 3.4 0.069 13.0 3.4 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger zinc_ribbon_6 PF14599.6 KDO26598.1 - 0.049 13.6 1.9 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon Zn-ribbon_8 PF09723.10 KDO26598.1 - 0.21 11.7 2.4 0.72 10.0 2.4 1.9 1 1 0 1 1 1 0 Zinc ribbon domain BUD22 PF09073.10 KDO26598.1 - 1.1 8.6 16.2 1.1 8.5 16.2 1.1 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 KDO26598.1 - 1.1 9.2 23.5 1.5 8.8 23.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Zip PF02535.22 KDO26598.1 - 2.6 7.2 5.3 2.7 7.1 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 KDO26598.1 - 2.8 7.1 9.3 3.5 6.8 9.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KDO26598.1 - 3.1 5.9 17.2 3.1 5.9 17.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KDO26598.1 - 3.3 7.0 17.3 3.8 6.8 17.3 1.1 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.6 KDO26598.1 - 3.4 7.6 12.5 3.6 7.5 12.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Torus PF16131.5 KDO26598.1 - 3.8 8.3 11.2 0.11 13.3 2.5 2.3 2 1 0 2 2 2 0 Torus domain Pox_Ag35 PF03286.14 KDO26598.1 - 4 7.2 15.5 5.4 6.8 15.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 KDO26598.1 - 4.4 6.2 6.0 4.5 6.1 6.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Rep_4 PF05797.11 KDO26598.1 - 6.6 5.8 7.8 7.4 5.6 7.8 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Presenilin PF01080.17 KDO26598.1 - 6.8 5.3 8.5 7.4 5.2 8.5 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KDO26598.1 - 8.4 5.1 9.3 9 5.0 9.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 KDO26598.1 - 9.3 4.9 8.2 9.9 4.8 8.2 1.1 1 0 0 1 1 1 0 Raftlin DUF2457 PF10446.9 KDO26598.1 - 9.3 5.3 15.7 13 4.8 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) adh_short PF00106.25 KDO26599.1 - 1.6e-22 80.0 0.0 7.5e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO26599.1 - 1.4e-18 67.3 0.0 6e-11 42.3 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO26599.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF1776 PF08643.10 KDO26599.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Spt4 PF06093.13 KDO26599.1 - 0.075 13.1 0.4 0.3 11.2 0.2 2.2 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger WH1 PF00568.23 KDO26599.1 - 0.099 12.6 0.2 0.28 11.1 0.1 1.9 1 1 1 2 2 2 0 WH1 domain SNF2_N PF00176.23 KDO26600.1 - 5.1e-55 186.6 5.0 3.1e-51 174.2 5.0 3.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO26600.1 - 1e-11 45.2 0.0 2.1e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO26600.1 - 7.5e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zip PF02535.22 KDO26602.1 - 3.7e-64 217.1 18.7 1.3e-42 146.2 10.8 3.0 1 1 2 3 3 3 3 ZIP Zinc transporter Gly-zipper_YMGG PF13441.6 KDO26602.1 - 0.0078 15.9 0.0 0.2 11.4 0.0 2.9 3 1 1 4 4 4 2 YMGG-like Gly-zipper V_ATPase_I PF01496.19 KDO26602.1 - 0.4 8.5 0.6 0.59 8.0 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans PF00520.31 KDO26603.1 - 1.1e-55 188.6 29.9 1e-29 103.5 13.4 2.3 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 KDO26603.1 - 7.6e-30 102.8 0.0 5.5e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO26603.1 - 4.5e-21 74.6 15.0 1.7e-11 43.9 7.4 2.9 2 0 0 2 2 2 2 Ion channel DUF4515 PF14988.6 KDO26604.1 - 0.082 12.7 0.5 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) PX PF00787.24 KDO26605.1 - 5.4e-08 32.8 0.0 2.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 PX domain PX PF00787.24 KDO26606.1 - 4.9e-09 36.2 0.0 5e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 PX domain Cep57_CLD_2 PF14197.6 KDO26606.1 - 0.22 11.7 1.7 1.3 9.2 0.5 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 KDO26607.1 - 0.085 12.9 5.3 0.15 12.1 5.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper PX PF00787.24 KDO26608.1 - 7.1e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PX domain Spc7 PF08317.11 KDO26608.1 - 0.13 11.2 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PX PF00787.24 KDO26610.1 - 5.9e-07 29.5 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 PX domain LpoB PF13036.6 KDO26610.1 - 0.041 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB MFS_2 PF13347.6 KDO26611.1 - 0.00026 19.7 0.3 0.00026 19.7 0.3 4.0 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_2 PF13347.6 KDO26612.1 - 2.1e-06 26.6 11.3 2.1e-06 26.6 11.3 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein LpoB PF13036.6 KDO26613.1 - 0.048 13.6 0.2 0.081 12.9 0.2 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Myosin_head PF00063.21 KDO26615.1 - 3.4e-126 422.2 0.0 4.9e-126 421.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 KDO26615.1 - 1.7e-11 44.1 0.3 3.9e-11 42.9 0.3 1.5 1 0 0 1 1 1 1 PX domain Myosin_N PF02736.19 KDO26615.1 - 8.2e-05 22.4 1.6 0.00019 21.2 1.6 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 KDO26615.1 - 0.00018 21.0 8.0 0.065 13.1 2.0 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF87 PF01935.17 KDO26615.1 - 0.0053 16.9 0.4 0.0053 16.9 0.4 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_6 PF12774.7 KDO26615.1 - 0.047 12.6 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KDO26615.1 - 0.05 13.9 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO26615.1 - 0.081 13.3 0.0 0.081 13.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain HALZ PF02183.18 KDO26615.1 - 0.18 12.1 3.1 1.8 8.9 1.8 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper PMSI1 PF15322.6 KDO26615.1 - 2 7.8 9.3 3.6 7.0 9.3 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Costars PF14705.6 KDO26616.1 - 1e-21 76.9 0.1 1.2e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Costars Lant_dehydr_N PF04738.13 KDO26616.1 - 0.18 9.8 0.0 0.2 9.7 0.0 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Kinesin PF00225.23 KDO26617.1 - 3.5e-106 354.9 0.0 1.1e-105 353.2 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO26617.1 - 2.1e-22 79.7 1.8 1.1e-21 77.4 0.0 3.2 4 0 0 4 4 4 1 Microtubule binding CENP-F_leu_zip PF10473.9 KDO26617.1 - 0.0046 17.0 4.7 0.0046 17.0 4.7 11.4 3 2 9 12 12 12 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA2 PF16740.5 KDO26617.1 - 0.0053 16.5 6.2 0.0053 16.5 6.2 10.7 6 4 4 11 11 11 3 Spindle and kinetochore-associated protein 2 Fez1 PF06818.15 KDO26617.1 - 0.01 16.3 13.1 0.01 16.3 13.1 8.7 1 1 6 7 7 7 0 Fez1 DUF695 PF05117.12 KDO26617.1 - 0.28 11.3 4.4 26 5.0 0.1 4.6 2 1 1 3 3 3 0 Family of unknown function (DUF695) DUF3389 PF11869.8 KDO26617.1 - 8.2 6.7 7.9 3.3 8.0 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3389) Ank_2 PF12796.7 KDO26618.1 - 2e-06 28.3 0.1 3.4e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26618.1 - 9.7e-05 22.6 0.1 0.00027 21.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO26618.1 - 0.00022 21.5 0.0 0.00052 20.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KDO26618.1 - 0.0024 18.2 0.3 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KDO26618.1 - 0.032 14.8 0.2 0.087 13.4 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MPLKIP PF15502.6 KDO26619.1 - 9e-10 38.6 9.9 4e-06 26.9 2.2 2.7 1 1 1 2 2 2 2 M-phase-specific PLK1-interacting protein TonB_N PF16031.5 KDO26619.1 - 0.084 13.4 3.9 0.13 12.8 3.9 1.2 1 0 0 1 1 1 0 TonB polyproline region Guanylate_cyc PF00211.20 KDO26620.1 - 4.3e-103 342.6 0.5 2.7e-50 170.5 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KDO26620.1 - 0.00033 20.1 2.0 0.37 10.2 0.1 2.3 2 0 0 2 2 2 2 Heme NO binding associated RNA_pol_Rpb1_5 PF04998.17 KDO26621.1 - 1.2e-103 346.2 0.0 2.1e-103 345.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KDO26621.1 - 4.6e-92 308.7 0.0 9.1e-92 307.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KDO26621.1 - 3.2e-74 248.7 0.0 6.9e-74 247.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KDO26621.1 - 2e-60 203.9 0.0 4.4e-60 202.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KDO26621.1 - 4.5e-50 169.1 4.1 7.8e-50 168.4 4.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KDO26621.1 - 3e-44 150.7 0.0 2.6e-43 147.7 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KDO26621.1 - 1.6e-30 105.2 0.1 3.4e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KDO26621.1 - 4.7e-24 83.4 230.7 0.0073 16.6 12.7 14.5 2 2 20 22 22 22 20 RNA polymerase Rpb1 C-terminal repeat Myosin_head PF00063.21 KDO26623.1 - 7e-215 715.2 0.0 1.2e-214 714.5 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 KDO26623.1 - 2.7e-11 43.5 0.3 6.4e-11 42.2 0.3 1.5 1 0 0 1 1 1 1 PX domain IQ PF00612.27 KDO26623.1 - 1.3e-06 27.7 22.7 0.0025 17.4 2.4 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif Myosin_N PF02736.19 KDO26623.1 - 0.0003 20.5 1.1 0.00079 19.2 1.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF87 PF01935.17 KDO26623.1 - 0.02 15.0 0.2 0.02 15.0 0.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 KDO26623.1 - 0.053 13.9 0.0 0.053 13.9 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KDO26623.1 - 0.057 13.7 0.1 0.38 11.0 0.1 2.5 1 0 0 1 1 1 0 AAA domain HALZ PF02183.18 KDO26623.1 - 0.44 10.8 3.1 2.7 8.3 1.8 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Zeta_toxin PF06414.12 KDO26623.1 - 1.6 8.0 12.1 1.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin PX PF00787.24 KDO26624.1 - 7.8e-12 45.2 0.0 1.4e-05 25.0 0.0 3.2 3 0 0 3 3 3 3 PX domain CBM_1 PF00734.18 KDO26625.1 - 2.3e-11 43.5 0.7 2.3e-11 43.5 0.7 3.7 4 2 0 4 4 4 2 Fungal cellulose binding domain PMP22_Claudin PF00822.20 KDO26625.1 - 0.098 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3616 PF12275.8 KDO26625.1 - 0.26 10.6 0.0 0.35 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) UCR_hinge PF02320.16 KDO26625.1 - 2.7 8.3 9.5 2.8 8.2 0.4 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein Myosin_head PF00063.21 KDO26626.1 - 5.1e-199 662.8 0.0 2.1e-190 634.4 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) DUF87 PF01935.17 KDO26626.1 - 0.011 15.8 0.4 0.011 15.8 0.4 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Myosin_N PF02736.19 KDO26626.1 - 0.011 15.5 1.5 0.03 14.2 1.5 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain PX PF00787.24 KDO26626.1 - 0.018 15.0 0.4 0.063 13.3 0.4 1.9 1 1 0 1 1 1 0 PX domain AAA_16 PF13191.6 KDO26626.1 - 0.04 14.3 0.0 0.04 14.3 0.0 3.0 3 1 1 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 KDO26626.1 - 0.078 13.2 0.6 0.35 11.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO26626.1 - 0.28 11.7 1.3 2 9.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain HALZ PF02183.18 KDO26626.1 - 2.3 8.5 9.3 2.1 8.6 1.8 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper PIP5K PF01504.18 KDO26627.1 - 3.9e-89 298.5 0.1 5.3e-89 298.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-CCCH PF00642.24 KDO26629.1 - 6.7e-05 22.7 0.2 0.0079 16.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO26629.1 - 0.61 10.0 5.6 2.7 7.9 1.7 3.2 2 1 0 2 2 2 0 CCCH-type zinc finger PhoLip_ATPase_C PF16212.5 KDO26633.1 - 8.6e-63 212.4 22.2 1e-62 212.2 22.2 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 KDO26633.1 - 0.0011 18.8 0.1 0.0016 18.2 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO26633.1 - 0.01 16.2 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KDO26634.1 - 5.3e-19 67.7 1.6 1.4e-18 66.3 1.6 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KDO26634.1 - 2.1e-07 30.9 0.0 5.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO26634.1 - 6.4e-06 26.6 0.0 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO26634.1 - 0.0025 17.3 2.8 0.022 14.3 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Lectin_N PF03954.14 KDO26634.1 - 0.085 12.6 0.2 0.53 10.0 0.1 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Cation_efflux PF01545.21 KDO26635.1 - 5.5e-29 101.3 1.8 6.9e-29 101.0 1.8 1.1 1 0 0 1 1 1 1 Cation efflux family NBD_C PF17042.5 KDO26635.1 - 0.22 12.0 1.9 5 7.6 0.2 3.2 4 0 0 4 4 4 0 Nucleotide-binding C-terminal domain MatE PF01554.18 KDO26636.1 - 3.7e-51 173.0 27.2 6.3e-27 94.2 5.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KDO26636.1 - 0.00063 19.8 15.9 0.00063 19.8 15.9 4.4 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain CLPTM1 PF05602.12 KDO26637.1 - 2.2e-109 366.4 0.0 3.7e-109 365.6 0.0 1.3 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Hpre_diP_synt_I PF07456.11 KDO26637.1 - 0.054 13.5 2.9 0.13 12.3 2.9 1.6 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I PQ-loop PF04193.14 KDO26637.1 - 0.65 9.8 9.0 3.1 7.7 1.1 3.4 3 1 0 3 3 3 0 PQ loop repeat RINGv PF12906.7 KDO26638.1 - 9.6e-12 44.8 7.6 1.4e-11 44.3 7.6 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KDO26638.1 - 0.048 14.0 6.1 0.083 13.2 6.1 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KDO26638.1 - 0.11 12.7 2.9 0.16 12.1 2.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF3959 PF13105.6 KDO26638.1 - 0.61 9.5 2.7 0.78 9.2 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF202 PF02656.15 KDO26638.1 - 0.75 10.3 5.8 1.3 9.5 4.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF4083 PF13314.6 KDO26638.1 - 3.9 7.5 5.3 2.1 8.3 3.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4083) zf-rbx1 PF12678.7 KDO26638.1 - 4.7 7.6 7.1 23 5.4 7.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase_Tyr PF07714.17 KDO26639.1 - 1.8e-27 96.3 0.0 2.3e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26639.1 - 8.1e-26 91.0 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO26639.1 - 0.0008 18.8 0.0 0.0054 16.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO26639.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PI31_Prot_N PF11566.8 KDO26640.1 - 9.6e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KDO26640.1 - 0.00014 23.0 12.6 0.00014 23.0 12.6 2.3 2 0 0 2 2 2 1 PI31 proteasome regulator Taq-exonuc PF09281.10 KDO26640.1 - 0.15 12.0 0.5 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Taq polymerase, exonuclease GCV_T PF01571.21 KDO26641.1 - 3.8e-12 46.1 0.1 8.1e-12 45.0 0.0 1.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain HSF_DNA-bind PF00447.17 KDO26642.1 - 1.1e-27 96.5 0.8 1.6e-27 95.9 0.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Tektin PF03148.14 KDO26642.1 - 0.026 13.3 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Tektin family PV-1 PF06637.11 KDO26643.1 - 0.0039 16.1 1.6 0.0041 16.0 1.6 1.1 1 0 0 1 1 1 1 PV-1 protein (PLVAP) Lebercilin PF15619.6 KDO26643.1 - 0.022 14.4 1.9 1.8 8.2 0.2 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 KDO26643.1 - 0.029 14.8 0.5 0.093 13.2 0.1 1.8 1 1 1 2 2 2 0 Cell division protein ZapB DUF724 PF05266.14 KDO26643.1 - 0.049 13.5 1.2 0.062 13.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) JIP_LZII PF16471.5 KDO26644.1 - 0.02 15.0 4.2 4.7 7.4 0.0 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Pyrophosphatase PF00719.19 KDO26644.1 - 0.023 14.5 1.5 0.031 14.1 1.5 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase Dala_Dala_lig_C PF07478.13 KDO26644.1 - 0.025 14.1 1.3 0.031 13.8 1.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Jnk-SapK_ap_N PF09744.9 KDO26644.1 - 0.038 14.2 13.8 0.031 14.5 6.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 KDO26644.1 - 0.04 13.8 9.6 0.052 13.4 9.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Phage_GPO PF05929.11 KDO26644.1 - 0.04 13.5 9.9 0.039 13.6 9.0 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ax_dynein_light PF10211.9 KDO26644.1 - 0.18 11.7 12.1 0.058 13.3 4.2 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4618 PF15397.6 KDO26644.1 - 0.25 10.7 9.6 0.3 10.5 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HAUS-augmin3 PF14932.6 KDO26644.1 - 0.29 10.7 14.5 0.077 12.6 10.1 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 KDO26644.1 - 0.34 9.8 13.0 0.39 9.5 13.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 KDO26644.1 - 0.75 10.1 6.9 0.18 12.1 1.1 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein FAD-SLDH PF12318.8 KDO26644.1 - 1.2 9.2 8.2 0.094 12.8 1.6 2.0 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase UCR_hinge PF02320.16 KDO26644.1 - 1.7 8.9 7.3 8.3 6.7 7.3 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF2703 PF10865.8 KDO26644.1 - 2.6 8.2 7.2 1.3 9.3 3.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) DUF3584 PF12128.8 KDO26644.1 - 3.1 5.2 18.4 1.2 6.5 6.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 KDO26644.1 - 4.6 7.8 7.5 1.6 9.3 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 ZapB PF06005.12 KDO26644.1 - 4.8 7.7 12.6 12 6.4 5.8 3.0 1 1 1 2 2 2 0 Cell division protein ZapB GrpE PF01025.19 KDO26644.1 - 4.9 6.8 11.3 36 4.0 11.3 2.1 1 1 0 1 1 1 0 GrpE GCN5L1 PF06320.13 KDO26644.1 - 6.4 7.0 14.6 7.7 6.7 7.6 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Thymidylate_kin PF02223.17 KDO26646.1 - 5.1e-48 163.2 0.0 5.9e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KDO26646.1 - 2.2e-05 25.0 0.1 0.0014 19.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 KDO26646.1 - 0.0021 18.0 0.0 0.023 14.6 0.0 2.1 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 KDO26646.1 - 0.023 14.9 0.3 0.087 13.0 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 KDO26646.1 - 0.034 14.2 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KDO26646.1 - 0.035 13.6 0.0 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.29 KDO26646.1 - 0.066 13.6 0.1 0.81 10.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 KDO26646.1 - 0.075 12.9 0.0 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF1707 PF08044.11 KDO26646.1 - 0.8 9.8 3.8 2.6 8.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) CHCH PF06747.13 KDO26647.1 - 2.8e-06 27.3 1.3 5.3e-06 26.4 1.3 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KDO26647.1 - 0.025 14.6 3.8 0.99 9.5 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1690 PF07956.11 KDO26647.1 - 0.028 14.9 0.2 0.03 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) UPF0203 PF05254.12 KDO26647.1 - 0.095 13.0 3.4 5.7 7.3 3.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KDO26647.1 - 3.7 8.0 8.3 0.17 12.3 2.5 1.8 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) MMR_HSR1 PF01926.23 KDO26649.1 - 9e-12 45.1 0.0 1.2e-05 25.4 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO26649.1 - 3.7e-05 23.7 0.3 9.3e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KDO26649.1 - 0.00012 21.7 0.1 0.012 15.1 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KDO26649.1 - 0.00012 22.1 0.9 0.0013 18.8 0.9 2.3 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KDO26649.1 - 0.0039 16.7 0.3 0.15 11.5 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B MeaB PF03308.16 KDO26649.1 - 0.0072 15.3 0.1 0.27 10.2 0.0 2.2 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 KDO26649.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KDO26649.1 - 0.014 15.1 0.5 0.014 15.1 0.5 1.5 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KDO26649.1 - 0.075 13.3 0.0 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KDO26649.1 - 0.1 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KDO26649.1 - 0.1 12.3 0.2 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Coleoptericin PF06286.11 KDO26649.1 - 0.15 12.2 0.0 0.96 9.6 0.0 2.1 2 0 0 2 2 2 0 Coleoptericin AAA_29 PF13555.6 KDO26649.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KDO26649.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ion_trans PF00520.31 KDO26650.1 - 1.9e-19 69.9 14.7 2.5e-19 69.5 14.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO26650.1 - 8.4e-11 41.7 7.1 8.4e-11 41.7 7.1 2.4 2 0 0 2 2 2 1 Ion channel Snapin_Pallidin PF14712.6 KDO26650.1 - 0.26 11.8 5.0 0.063 13.7 1.9 1.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF4231 PF14015.6 KDO26650.1 - 4.5 7.8 9.3 2.2 8.8 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Pex14_N PF04695.13 KDO26652.1 - 0.0059 17.3 1.2 0.0082 16.8 1.2 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sensor PF13796.6 KDO26652.1 - 0.037 14.1 3.5 0.055 13.5 3.5 1.3 1 0 0 1 1 1 0 Putative sensor MATalpha_HMGbox PF04769.12 KDO26654.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box GCV_T PF01571.21 KDO26655.1 - 2e-68 230.5 0.2 2.7e-68 230.1 0.2 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KDO26655.1 - 2e-57 195.4 0.2 3.2e-57 194.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KDO26655.1 - 7.1e-17 61.1 0.0 1.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KDO26655.1 - 9.2e-12 45.1 0.1 1.9e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain SoxG PF04268.12 KDO26655.1 - 4.1e-06 27.0 0.2 7.8e-05 22.9 0.2 2.4 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family FAD_binding_2 PF00890.24 KDO26655.1 - 1.2e-05 24.6 0.0 0.00024 20.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KDO26655.1 - 1.2e-05 24.8 0.3 0.038 13.2 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KDO26655.1 - 0.00016 21.1 0.1 0.083 12.1 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO26655.1 - 0.00046 20.4 0.3 0.0023 18.1 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO26655.1 - 0.00059 19.2 0.1 0.0025 17.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO26655.1 - 0.0066 15.7 0.3 0.019 14.2 0.3 1.8 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KDO26655.1 - 0.0098 15.9 1.8 0.98 9.4 0.2 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding ApbA PF02558.16 KDO26655.1 - 0.011 15.4 0.2 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KDO26655.1 - 0.013 16.1 0.3 0.05 14.2 0.5 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KDO26655.1 - 0.031 14.7 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KDO26655.1 - 0.16 11.1 1.5 0.24 10.4 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KDO26655.1 - 0.17 11.8 0.5 0.31 10.9 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KDO26655.1 - 0.21 10.9 0.5 0.4 10.0 0.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase WD40 PF00400.32 KDO26656.1 - 0.00018 22.2 10.8 9.5 7.3 0.5 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Frtz PF11768.8 KDO26656.1 - 0.039 12.3 0.0 0.069 11.5 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz BRCA2 PF00634.18 KDO26656.1 - 0.1 12.3 0.7 16 5.3 0.0 3.1 3 0 0 3 3 3 0 BRCA2 repeat Peptidase_M3_N PF08439.10 KDO26656.1 - 0.26 11.6 3.4 1.6 9.1 0.6 2.6 2 0 0 2 2 2 0 Oligopeptidase F SpoIIE PF07228.12 KDO26657.1 - 1.3e-07 31.8 0.0 2.8e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KDO26657.1 - 1.6e-06 27.9 1.0 2.4e-06 27.4 0.2 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C CRM1_C PF08767.11 KDO26658.1 - 9.2e-115 383.2 3.9 5.3e-114 380.7 1.0 2.5 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KDO26658.1 - 1.6e-34 119.2 4.8 1.6e-34 119.2 4.8 3.5 4 1 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KDO26658.1 - 1.1e-30 105.0 1.9 1.6e-30 104.6 0.6 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KDO26658.1 - 2.1e-29 101.4 1.6 2.1e-29 101.4 1.6 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KDO26658.1 - 3.4e-18 64.9 0.8 9e-18 63.5 0.8 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KDO26658.1 - 7e-12 45.1 0.0 3.1e-11 43.0 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain BID PF06393.11 KDO26658.1 - 0.00074 19.1 0.2 0.0052 16.4 0.1 2.4 2 0 0 2 2 2 1 BH3 interacting domain (BID) HMMR_N PF15905.5 KDO26660.1 - 0.0014 18.2 17.1 0.0014 18.2 17.1 9.1 3 1 5 9 9 9 4 Hyaluronan mediated motility receptor N-terminal VGPC1_C PF16799.5 KDO26660.1 - 0.0019 18.2 0.4 0.0019 18.2 0.4 5.9 6 0 0 6 6 6 1 C-terminal membrane-localisation domain of ion-channel, VCN1 TPR_MLP1_2 PF07926.12 KDO26660.1 - 0.011 15.8 18.4 0.011 15.8 18.4 14.9 3 1 8 13 13 13 0 TPR/MLP1/MLP2-like protein TolA PF06519.11 KDO26661.1 - 0.0062 16.7 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 TolA C-terminal LRR_4 PF12799.7 KDO26662.1 - 0.26 11.8 2.2 8.6 6.9 0.1 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF5367 PF17329.2 KDO26663.1 - 0.38 10.9 0.1 0.38 10.9 0.1 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5367) CAP PF00188.26 KDO26666.1 - 5.8e-29 101.5 2.9 2.9e-13 50.8 0.8 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family FGE-sulfatase PF03781.16 KDO26666.1 - 0.00034 20.3 2.0 0.069 12.7 0.3 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 PT PF04886.12 KDO26666.1 - 0.0013 18.2 46.6 1.1e+04 -3.9 46.6 3.8 1 1 0 1 1 1 0 PT repeat DUF3212 PF11486.8 KDO26666.1 - 0.0019 18.2 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3212) U71 PF17474.2 KDO26666.1 - 0.0036 17.2 0.1 4 7.4 0.0 2.6 2 0 0 2 2 2 2 Tegument protein UL11 homolog MutS_IV PF05190.18 KDO26666.1 - 0.007 16.7 0.0 3.8 7.9 0.0 2.3 2 0 0 2 2 2 2 MutS family domain IV FG-GAP PF01839.23 KDO26666.1 - 0.073 13.2 0.0 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 FG-GAP repeat H_lectin PF09458.10 KDO26666.1 - 0.086 13.0 0.0 7.8 6.8 0.0 2.5 2 0 0 2 2 2 0 H-type lectin domain CAP PF00188.26 KDO26670.1 - 2.6e-19 70.3 4.7 1.1e-09 39.2 0.6 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family DUF3212 PF11486.8 KDO26670.1 - 0.0099 15.9 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3212) AMP-binding PF00501.28 KDO26671.1 - 1.5e-15 56.8 0.5 7.5e-14 51.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF2367 PF10164.9 KDO26672.1 - 0.00083 19.8 3.6 0.0013 19.1 3.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Guanylate_cyc_2 PF09778.9 KDO26673.1 - 7.5e-40 136.5 0.0 9.4e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C70 PF12385.8 KDO26673.1 - 1.8e-06 28.0 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 KDO26673.1 - 0.0013 18.5 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C39 family Peptidase_C39_2 PF13529.6 KDO26673.1 - 0.0016 19.0 0.0 0.021 15.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family VHS PF00790.19 KDO26674.1 - 1e-24 87.0 0.0 2.8e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KDO26674.1 - 4.5e-10 39.7 8.0 1.1e-09 38.4 4.1 2.7 2 0 0 2 2 2 1 GAT domain Ank_2 PF12796.7 KDO26675.1 - 2.5e-10 40.8 4.6 2.1e-05 25.0 0.4 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26675.1 - 7.8e-07 29.5 10.5 0.0052 17.3 0.1 5.0 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO26675.1 - 0.00013 22.2 5.7 11 6.5 0.0 5.2 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26675.1 - 0.00042 20.5 2.8 48 5.0 0.0 5.7 5 1 1 6 6 6 0 Ankyrin repeat PLAC8 PF04749.17 KDO26676.1 - 1.2e-17 64.8 14.1 2e-17 64.0 14.1 1.4 1 0 0 1 1 1 1 PLAC8 family BT1 PF03092.16 KDO26677.1 - 0.00033 19.0 3.5 0.0018 16.6 0.9 2.5 2 0 0 2 2 2 2 BT1 family Peptidase_C1 PF00112.23 KDO26679.1 - 9.9e-56 189.3 2.7 1.3e-55 188.9 2.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO26679.1 - 0.00013 20.9 0.3 0.053 12.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO26680.1 - 9.9e-57 192.5 4.9 1.3e-56 192.1 4.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease CENP-T_C PF15511.6 KDO26681.1 - 1.1e-08 35.1 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO26681.1 - 8.7e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO26681.1 - 0.00047 20.3 0.1 0.00063 19.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KDO26681.1 - 0.0025 18.2 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KDO26681.1 - 0.0025 18.1 0.1 0.0034 17.6 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO26681.1 - 0.015 15.4 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO26681.1 - 0.064 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KDO26682.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO26682.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO26682.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO26682.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO26682.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO26682.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO26682.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KDO26683.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO26683.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO26683.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO26683.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO26683.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO26683.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO26683.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KDO26684.1 - 8.4e-54 181.5 1.2 9.3e-54 181.3 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KDO26684.1 - 0.00033 20.7 0.3 0.00058 20.0 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KDO26684.1 - 0.00044 20.8 2.3 0.00055 20.5 2.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KDO26684.1 - 0.0015 18.9 0.0 0.0023 18.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KDO26684.1 - 0.092 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO26684.1 - 0.12 12.5 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Thioredoxin_4 PF13462.6 KDO26685.1 - 2.2e-09 37.7 0.0 3.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KDO26685.1 - 1.9e-05 24.5 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_14 PF18402.1 KDO26685.1 - 0.06 13.3 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4537 PF15057.6 KDO26686.1 - 1.6e-08 34.6 0.3 0.4 10.7 0.2 4.8 3 1 1 4 4 4 3 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KDO26686.1 - 0.00075 19.6 0.0 0.0046 17.0 0.0 2.3 2 0 0 2 2 2 1 SGF29 tudor-like domain TDA11 PF17084.5 KDO26686.1 - 0.026 13.5 2.5 0.53 9.2 0.1 2.1 2 0 0 2 2 2 0 Topoisomerase I damage affected protein 11 Tudor_3 PF18115.1 KDO26686.1 - 0.15 12.0 10.3 18 5.3 0.0 4.9 5 0 0 5 5 5 0 DNA repair protein Crb2 Tudor domain V-SNARE PF05008.15 KDO26686.1 - 1.1 9.7 3.0 29 5.1 0.3 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PH PF00169.29 KDO26687.1 - 3e-06 27.7 0.0 4.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PH domain Spc7 PF08317.11 KDO26688.1 - 0.0012 17.8 2.3 0.0012 17.8 2.3 2.7 1 1 2 3 3 3 1 Spc7 kinetochore protein Phage_TAC_2 PF06894.11 KDO26688.1 - 0.088 12.6 5.3 4.3 7.2 1.0 3.3 2 1 0 2 2 2 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G HisKA_3 PF07730.13 KDO26688.1 - 0.15 12.6 7.5 3.7 8.1 0.1 3.8 3 2 1 4 4 4 0 Histidine kinase Aida_N PF08910.10 KDO26688.1 - 0.5 10.8 3.8 2.3 8.7 0.2 2.8 2 1 0 2 2 2 0 Aida N-terminus Fib_alpha PF08702.10 KDO26688.1 - 0.55 10.4 8.1 1.7 8.8 0.5 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 KDO26688.1 - 0.77 9.6 6.3 0.58 10.0 1.8 2.8 2 1 1 3 3 3 0 CdvA-like coiled-coil domain EspB_PE PF18625.1 KDO26688.1 - 1.6 9.2 7.7 0.67 10.4 0.3 3.4 2 2 1 4 4 4 0 ESX-1 secreted protein B PE domain ISG65-75 PF11727.8 KDO26688.1 - 1.8 7.7 12.1 0.074 12.3 4.4 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein DivIVA PF05103.13 KDO26688.1 - 3.8 7.6 21.0 0.053 13.6 4.5 3.6 2 1 1 3 3 3 0 DivIVA protein CREPT PF16566.5 KDO26688.1 - 4.4 7.5 8.9 0.6 10.3 2.3 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Tektin PF03148.14 KDO26688.1 - 6.1 5.5 13.5 1 8.0 0.4 3.3 1 1 1 3 3 3 0 Tektin family Prominin PF05478.11 KDO26688.1 - 7 4.5 12.7 0.73 7.7 6.9 1.8 1 1 1 2 2 2 0 Prominin HAUS6_N PF14661.6 KDO26688.1 - 8.5 5.9 7.4 1.4 8.5 1.1 2.2 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF647 PF04884.14 KDO26689.1 - 1.8e-66 224.2 0.7 2.5e-66 223.8 0.7 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Beta-TrCP_D PF12125.8 KDO26689.1 - 0.049 13.5 0.3 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 D domain of beta-TrCP FTHFS PF01268.19 KDO26690.1 - 4e-195 649.2 1.3 4.9e-195 648.9 1.3 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Tudor_2 PF18104.1 KDO26691.1 - 0.017 14.8 0.1 0.64 9.7 0.0 3.4 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 KDO26692.1 - 0.044 13.6 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Nmad2 PF18753.1 KDO26692.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 RCC1 PF00415.18 KDO26693.1 - 1.9e-14 54.0 22.5 5.3e-06 27.0 1.2 6.2 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO26693.1 - 1.9e-09 37.1 38.0 0.043 13.6 4.9 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KDO26693.1 - 0.0038 17.1 0.2 0.012 15.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like Mcl1_mid PF12341.8 KDO26693.1 - 0.057 12.8 0.0 0.21 10.9 0.0 1.6 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region DUF1921 PF09081.10 KDO26693.1 - 0.061 13.6 0.9 4.6 7.6 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) F-box_4 PF15966.5 KDO26693.1 - 0.12 12.2 0.3 0.7 9.8 0.1 2.0 2 0 0 2 2 2 0 F-box Ank_2 PF12796.7 KDO26694.1 - 5.3e-29 100.7 10.7 3.3e-13 50.0 0.2 5.2 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26694.1 - 8.9e-29 99.5 15.5 1e-08 35.5 0.1 7.5 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO26694.1 - 2.1e-23 82.1 10.8 5.3e-06 26.6 0.0 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26694.1 - 3.6e-21 73.0 13.8 0.0016 18.8 0.0 9.6 9 1 1 10 10 10 6 Ankyrin repeat Ank PF00023.30 KDO26694.1 - 1.6e-20 72.6 21.2 0.00022 21.5 0.0 8.4 9 0 0 9 9 9 5 Ankyrin repeat ATP-synt_ab PF00006.25 KDO26695.1 - 1.2e-66 224.4 0.0 1.6e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KDO26695.1 - 2.9e-11 43.7 0.4 5.4e-11 42.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Myb_DNA-binding PF00249.31 KDO26696.1 - 6.2e-06 26.3 0.0 2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SSXT PF05030.12 KDO26696.1 - 2.6e-05 23.7 0.2 5.2e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) TRP PF06011.12 KDO26697.1 - 3.8e-15 55.6 22.8 1.1e-14 54.0 22.8 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF4834 PF16118.5 KDO26697.1 - 0.16 13.0 0.0 32 5.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4190 PF13828.6 KDO26697.1 - 0.3 10.9 13.5 0.12 12.1 0.3 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) MKRN1_C PF15815.5 KDO26698.1 - 0.041 14.3 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal CPBP PF02517.16 KDO26699.1 - 3.1e-12 46.7 2.9 3.1e-12 46.7 2.9 2.9 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease TMEMspv1-c74-12 PF11044.8 KDO26699.1 - 0.094 12.7 0.5 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TRP PF06011.12 KDO26700.1 - 4.5e-07 29.0 37.1 1.4e-06 27.4 37.1 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Phage_holin_3_6 PF07332.11 KDO26700.1 - 0.0082 16.2 0.1 0.0082 16.2 0.1 5.3 4 1 0 4 4 4 1 Putative Actinobacterial Holin-X, holin superfamily III Mobilization_B PF17511.2 KDO26700.1 - 2.9 8.3 5.8 1 9.7 0.6 2.5 2 0 0 2 2 2 0 Mobilization protein B Tmemb_9 PF05434.11 KDO26700.1 - 7.2 6.5 5.7 18 5.2 0.1 3.6 4 0 0 4 4 4 0 TMEM9 TMEM52 PF14979.6 KDO26700.1 - 8.6 6.3 6.5 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Transmembrane 52 Senescence_reg PF04520.13 KDO26702.1 - 0.0044 17.9 5.8 0.0081 17.0 5.8 1.4 1 1 0 1 1 1 1 Senescence regulator Mg_chelatase_C PF13335.6 KDO26702.1 - 0.16 12.6 1.5 0.25 12.0 1.5 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Sec6 PF06046.13 KDO26702.1 - 0.23 9.8 1.2 0.29 9.4 1.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 DUF1075 PF06388.11 KDO26702.1 - 0.55 10.3 2.9 9.4 6.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1075) Gypsy PF07253.11 KDO26705.1 - 0.017 13.7 2.5 0.019 13.5 2.5 1.1 1 0 0 1 1 1 0 Gypsy protein Adeno_E3_CR2 PF02439.15 KDO26706.1 - 0.026 14.3 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Miga PF10265.9 KDO26706.1 - 0.2 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Mitoguardin FAM104 PF15434.6 KDO26706.1 - 0.28 11.8 3.5 0.58 10.7 3.5 1.5 1 0 0 1 1 1 0 Family 104 DEC-1_N PF04625.13 KDO26706.1 - 9.8 5.1 9.0 4.6 6.2 3.4 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Mito_carr PF00153.27 KDO26707.1 - 1.1e-23 82.9 4.7 2.1e-09 37.2 0.1 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Mito_carr PF00153.27 KDO26708.1 - 1e-23 83.1 4.4 1.1e-07 31.6 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.25 KDO26709.1 - 9e-62 208.8 0.0 1.2e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26709.1 - 1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_4 PF14555.6 KDO26709.1 - 6.6e-06 25.8 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain APH PF01636.23 KDO26709.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KDO26709.1 - 0.00093 19.9 0.3 0.0024 18.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KDO26709.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KDO26709.1 - 0.015 15.0 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3658 PF12395.8 KDO26710.1 - 0.015 15.2 2.3 0.056 13.3 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function Na_Ca_ex PF01699.24 KDO26711.1 - 9.6e-41 139.2 35.0 2.2e-22 79.6 15.8 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Pex24p PF06398.11 KDO26711.1 - 0.31 10.0 3.2 0.34 9.8 2.2 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin C2 PF00168.30 KDO26713.1 - 1.1e-14 54.5 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KDO26713.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.6 1 1 0 1 1 1 0 PH domain zf-RING_2 PF13639.6 KDO26714.1 - 1.4e-13 50.9 5.4 3.2e-13 49.8 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO26714.1 - 2.5e-11 43.2 4.6 5.7e-11 42.1 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO26714.1 - 4.7e-10 39.6 6.4 1.3e-09 38.2 6.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO26714.1 - 1.8e-09 37.3 4.0 3.9e-09 36.2 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO26714.1 - 2.5e-08 33.8 1.3 2.5e-08 33.8 1.3 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO26714.1 - 3.6e-08 33.0 1.2 9.3e-08 31.7 1.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO26714.1 - 5.9e-08 32.6 2.2 1.3e-07 31.5 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO26714.1 - 7.2e-06 26.0 2.6 1.5e-05 25.0 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PX PF00787.24 KDO26714.1 - 1.9e-05 24.6 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 PX domain zf-C3HC4_3 PF13920.6 KDO26714.1 - 3e-05 23.8 2.5 3e-05 23.8 2.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KDO26714.1 - 0.0005 19.8 2.1 0.0011 18.7 2.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KDO26714.1 - 0.0014 18.2 6.9 0.003 17.1 6.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KDO26714.1 - 0.0017 18.4 4.5 0.0066 16.6 4.5 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KDO26714.1 - 0.0034 17.5 2.7 0.0034 17.5 2.7 1.9 2 1 0 2 2 2 1 RING-variant domain Prok-RING_4 PF14447.6 KDO26714.1 - 0.0058 16.5 8.0 0.051 13.4 6.6 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KDO26714.1 - 0.013 15.8 2.5 0.026 14.8 2.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 KDO26714.1 - 0.066 13.0 5.3 0.085 12.7 3.8 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KDO26714.1 - 0.25 11.3 3.4 0.64 10.0 3.4 1.8 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KDO26714.1 - 0.36 11.0 8.1 1.5 9.1 6.8 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 KDO26714.1 - 2.5 8.1 9.5 0.22 11.5 0.8 2.9 3 1 1 4 4 3 0 Prokaryotic RING finger family 1 HlyE PF06109.13 KDO26715.1 - 5.6e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Haemolysin E (HlyE) HlyE PF06109.13 KDO26716.1 - 5.6e-08 32.4 0.2 8.8e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Haemolysin E (HlyE) adh_short PF00106.25 KDO26718.1 - 1.2e-20 73.8 0.5 2e-17 63.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KDO26718.1 - 3.3e-12 46.5 0.2 2e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO26718.1 - 5.3e-07 29.7 0.6 8.4e-07 29.1 0.2 1.5 2 0 0 2 2 2 1 KR domain Importin_rep_3 PF18806.1 KDO26719.1 - 0.0028 17.7 0.0 0.028 14.5 0.0 2.7 3 0 0 3 3 3 1 Importin 13 repeat API5 PF05918.11 KDO26719.1 - 0.26 10.1 0.3 19 3.9 0.1 2.3 1 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) SPATA24 PF15175.6 KDO26720.1 - 0.05 13.5 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Caskin-Pro-rich PF16907.5 KDO26721.1 - 0.61 10.7 2.4 0.87 10.2 2.4 1.3 1 0 0 1 1 1 0 Proline rich region of Caskin proteins zf-C3HC4_3 PF13920.6 KDO26722.1 - 3.9e-13 49.0 12.3 7e-13 48.2 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO26722.1 - 3.6e-08 33.1 12.1 3.6e-08 33.1 12.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO26722.1 - 0.00064 20.0 13.9 0.0014 18.9 13.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KDO26722.1 - 0.2 11.7 13.6 0.38 10.7 13.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Arf PF00025.21 KDO26723.1 - 4e-65 218.5 0.3 4.7e-65 218.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO26723.1 - 3.3e-14 53.1 0.0 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO26723.1 - 5.5e-13 48.7 0.0 6.7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KDO26723.1 - 2.3e-12 46.7 0.0 2.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KDO26723.1 - 1.4e-11 44.2 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KDO26723.1 - 7.6e-07 28.6 0.1 0.0015 17.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO26723.1 - 8.6e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO26723.1 - 0.0015 18.1 0.8 0.0028 17.2 0.8 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 KDO26723.1 - 0.022 14.9 0.4 0.085 13.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KDO26723.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Tubulin PF00091.25 KDO26726.1 - 3.8e-65 219.8 0.0 6e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO26726.1 - 5.6e-48 162.3 0.0 8.6e-48 161.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KDO26726.1 - 0.0036 17.0 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain PseudoU_synth_1 PF01416.20 KDO26727.1 - 4.9e-25 88.1 0.1 1.5e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 KDO26727.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) SdpA PF17418.2 KDO26728.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Sporulation delaying protein SdpA ATP-gua_PtransN PF02807.15 KDO26728.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain DIOX_N PF14226.6 KDO26729.1 - 7.3e-19 68.7 0.0 1.2e-18 68.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO26729.1 - 3.6e-08 33.8 0.0 6.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCI PF01399.27 KDO26730.1 - 2e-16 60.4 0.1 4.4e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 KDO26730.1 - 0.015 16.0 0.6 1.7 9.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.22 KDO26731.1 - 2e-14 54.0 0.0 2e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KDO26731.1 - 1.4e-11 43.9 0.6 4.9e-11 42.2 0.6 2.0 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KDO26731.1 - 0.027 14.3 0.6 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 S4 domain Pro_isomerase PF00160.21 KDO26732.1 - 8.5e-21 74.9 0.0 1.1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFS_1 PF07690.16 KDO26733.1 - 1.3e-24 86.8 39.2 3.9e-24 85.2 36.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KDO26733.1 - 8.6e-12 44.1 6.4 7.1e-08 31.2 0.0 3.3 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO26733.1 - 4.7e-10 38.9 6.5 4.7e-10 38.9 6.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Ricin_B_lectin PF00652.22 KDO26735.1 - 2.7e-22 79.3 14.6 2.1e-12 47.4 8.9 3.1 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26735.1 - 3.9e-09 37.1 12.6 0.00092 19.9 2.4 4.2 2 2 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO26735.1 - 4.4e-07 29.6 1.8 3.3e-05 23.5 0.9 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain N_Asn_amidohyd PF14736.6 KDO26739.1 - 1.5e-21 76.8 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Ricin_B_lectin PF00652.22 KDO26740.1 - 2.5e-18 66.6 0.2 9.9e-11 42.0 0.4 3.2 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26740.1 - 7.7e-07 29.8 0.1 0.011 16.4 0.0 3.7 2 1 2 4 4 4 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO26740.1 - 0.00021 20.9 0.1 0.027 14.1 0.0 2.7 1 1 2 3 3 3 2 Cytolethal distending toxin A/C domain Ricin_B_lectin PF00652.22 KDO26741.1 - 2.1e-21 76.5 6.9 1.8e-14 54.1 5.3 3.2 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26741.1 - 7e-08 33.1 13.6 1.1e-05 26.0 2.6 4.4 2 2 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO26741.1 - 2.1e-07 30.7 2.4 1.5e-05 24.6 2.7 2.6 1 1 0 2 2 2 1 Cytolethal distending toxin A/C domain ET PF01684.16 KDO26741.1 - 0.067 13.5 2.3 3.9 7.9 0.1 3.4 2 2 1 3 3 3 0 ET module fragilysinNterm PF16376.5 KDO26741.1 - 0.11 12.3 0.4 5.7 6.7 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of fragilysin PQQ PF01011.21 KDO26741.1 - 0.12 12.4 0.7 3.6 7.7 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Ricin_B_lectin PF00652.22 KDO26742.1 - 2.4e-19 69.9 5.5 6.1e-14 52.4 4.4 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26742.1 - 1.1e-09 38.8 6.2 0.0039 17.9 0.2 3.6 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO26742.1 - 3.5e-05 23.4 4.5 4.7e-05 23.0 2.4 2.2 1 1 1 2 2 2 1 Cytolethal distending toxin A/C domain EF-hand_7 PF13499.6 KDO26743.1 - 1.3e-11 44.8 3.8 0.0082 16.6 3.5 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO26743.1 - 3.5e-10 38.7 4.2 0.0034 16.8 1.6 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KDO26743.1 - 1.9e-09 36.7 3.1 0.011 15.6 0.3 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KDO26743.1 - 1.8e-07 30.4 7.7 0.00052 19.4 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO26743.1 - 2e-05 24.4 0.4 0.13 12.1 1.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair zf-HC5HC2H_2 PF13832.6 KDO26745.1 - 5.7e-29 100.5 34.2 3.9e-17 62.4 10.9 3.2 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO26745.1 - 1.3e-24 86.3 18.9 1.3e-13 50.9 9.9 4.2 4 1 1 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.6 KDO26745.1 - 6.4e-09 35.2 5.2 6.4e-09 35.2 5.2 4.0 5 0 0 5 5 5 1 PHD-finger PHD PF00628.29 KDO26745.1 - 9.7e-09 35.0 50.1 2.2e-08 33.8 7.7 5.6 5 1 0 5 5 5 3 PHD-finger Prok-RING_1 PF14446.6 KDO26745.1 - 0.0014 18.5 5.4 0.0014 18.5 5.4 4.6 5 0 0 5 5 5 1 Prokaryotic RING finger family 1 C1_2 PF03107.16 KDO26745.1 - 0.0047 17.2 1.4 0.0047 17.2 1.4 4.6 5 0 0 5 5 5 2 C1 domain C1_1 PF00130.22 KDO26745.1 - 0.0055 16.6 0.4 0.0055 16.6 0.4 4.8 4 1 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PhnA_Zn_Ribbon PF08274.12 KDO26745.1 - 0.026 14.5 2.5 0.094 12.7 0.8 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CHAD PF05235.14 KDO26745.1 - 0.053 13.5 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 CHAD domain DZR PF12773.7 KDO26746.1 - 0.0016 18.4 3.3 0.0022 18.0 1.5 2.1 2 1 0 2 2 2 1 Double zinc ribbon zf-C4pol PF14260.6 KDO26746.1 - 0.031 14.7 7.1 0.072 13.6 7.1 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Mu-like_Com PF10122.9 KDO26746.1 - 0.034 13.6 1.1 1.4 8.4 0.1 2.7 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-Sec23_Sec24 PF04810.15 KDO26746.1 - 0.14 12.2 4.2 16 5.6 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FAM76 PF16046.5 KDO26746.1 - 0.34 10.2 4.3 0.47 9.8 4.3 1.2 1 0 0 1 1 1 0 FAM76 protein zinc_ribbon_2 PF13240.6 KDO26746.1 - 0.38 10.5 2.2 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 KDO26746.1 - 3.8 6.9 7.3 0.38 10.1 1.0 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others YchF-GTPase_C PF06071.13 KDO26747.1 - 1.3e-38 131.1 0.6 2.6e-38 130.1 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KDO26747.1 - 9.8e-21 74.0 0.0 2.1e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO26747.1 - 3.5e-07 29.9 0.0 6.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KDO26747.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3834 PF12916.7 KDO26747.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Glyco_hydro_6 PF01341.17 KDO26748.1 - 5.1e-47 161.1 0.7 1.2e-46 159.9 0.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PNRC PF15365.6 KDO26748.1 - 1.6e-06 27.7 3.8 1.6e-06 27.7 3.8 2.9 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif PAT1 PF09770.9 KDO26748.1 - 1.5 7.0 11.2 2.5 6.3 11.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pur_ac_phosph_N PF16656.5 KDO26749.1 - 5.6e-16 58.9 4.0 1.6e-15 57.4 4.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KDO26749.1 - 3.2e-15 57.2 0.7 5e-15 56.5 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO26749.1 - 3.9e-08 34.0 0.2 1.1e-07 32.6 0.2 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C DUF2369 PF10179.9 KDO26749.1 - 0.00027 21.2 0.6 0.00061 20.1 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 KDO26749.1 - 0.012 16.1 0.4 0.026 15.1 0.4 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Ank_2 PF12796.7 KDO26751.1 - 4.6e-95 312.4 29.5 1.2e-16 61.0 1.5 7.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26751.1 - 8.3e-56 185.7 17.5 8.2e-07 29.5 0.8 11.2 2 2 9 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26751.1 - 1.5e-50 163.2 14.7 0.00038 20.7 0.0 14.4 15 0 0 15 15 15 13 Ankyrin repeat Ank PF00023.30 KDO26751.1 - 5.5e-47 156.2 41.2 4.5e-05 23.7 0.1 14.5 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.6 KDO26751.1 - 2.2e-38 129.8 24.9 1.6e-07 31.4 0.1 10.4 4 2 7 11 11 11 9 Ankyrin repeats (many copies) PsbJ PF01788.17 KDO26751.1 - 0.0036 17.1 0.1 5.4 7.0 0.0 3.0 3 0 0 3 3 3 2 PsbJ FliT PF05400.13 KDO26751.1 - 0.048 14.5 0.2 7 7.5 0.0 3.5 3 1 0 3 3 3 0 Flagellar protein FliT PEGA PF08308.11 KDO26751.1 - 0.063 13.2 0.0 16 5.5 0.0 4.6 7 0 0 7 7 7 0 PEGA domain VIGSSK PF14773.6 KDO26751.1 - 0.17 12.0 0.7 13 6.0 0.1 3.3 2 1 1 3 3 3 0 Helicase-associated putative binding domain, C-terminal Radical_SAM_C PF16199.5 KDO26751.1 - 0.19 11.8 0.0 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Radical_SAM C-terminal domain FCD PF07729.12 KDO26751.1 - 1.1 9.7 8.0 24 5.3 0.0 4.7 5 1 0 5 5 5 0 FCD domain Imm_superinfect PF14373.6 KDO26751.1 - 2.8 7.9 9.5 35 4.4 0.0 5.9 7 0 0 7 7 7 0 Superinfection immunity protein Disintegrin PF00200.23 KDO26753.1 - 4e-22 78.8 84.2 3.4e-05 24.6 16.1 7.6 5 4 1 6 6 6 6 Disintegrin Baculo_PEP_C PF04513.12 KDO26753.1 - 0.0024 17.9 0.0 0.98 9.5 0.0 3.2 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1206 PF06724.11 KDO26753.1 - 2.1 8.5 5.4 0.33 11.0 1.6 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) MtrB PF05440.12 KDO26753.1 - 5.9 7.4 14.2 5.2 7.6 0.6 4.3 1 1 4 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B PMC2NT PF08066.12 KDO26753.1 - 9.1 7.0 10.5 15 6.3 1.2 5.0 4 2 1 5 5 5 0 PMC2NT (NUC016) domain Lzipper-MIP1 PF14389.6 KDO26754.1 - 0.16 12.3 9.6 14 6.1 0.4 4.3 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ABC_tran_CTD PF16326.5 KDO26754.1 - 0.24 11.7 7.3 0.38 11.0 0.8 3.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain GRDP-like PF07173.12 KDO26755.1 - 2.8e-05 24.8 0.2 4.7e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like DCB PF16213.5 KDO26756.1 - 0.04 13.6 0.2 0.077 12.7 0.1 1.4 1 1 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 CAP_GLY PF01302.25 KDO26757.1 - 1.2e-23 82.9 0.9 1.9e-23 82.2 0.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Fib_alpha PF08702.10 KDO26757.1 - 1 9.6 38.6 0.47 10.6 7.9 5.8 4 2 2 6 6 6 0 Fibrinogen alpha/beta chain family HSP70 PF00012.20 KDO26758.1 - 3.1e-130 435.2 6.8 8.4e-129 430.5 6.8 2.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO26758.1 - 4.3e-06 25.8 0.1 1e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 MreB/Mbl protein LytR_cpsA_psr PF03816.14 KDO26758.1 - 0.00055 20.1 0.0 0.015 15.4 0.1 2.5 2 0 0 2 2 2 1 Cell envelope-related transcriptional attenuator domain CDT1 PF08839.11 KDO26758.1 - 0.074 13.4 0.4 0.24 11.7 0.4 1.9 1 0 0 1 1 1 0 DNA replication factor CDT1 like Myb_DNA-binding PF00249.31 KDO26759.1 - 4.3e-12 46.0 0.1 1.1e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KDO26759.1 - 8.2e-06 26.1 0.0 3.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KDO26759.1 - 8.5e-06 25.9 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RSN1_7TM PF02714.15 KDO26761.1 - 2.9e-06 26.8 9.3 2.9e-06 26.8 9.3 2.2 3 1 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KDO26761.1 - 0.00084 19.6 0.0 0.0073 16.6 0.0 2.1 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 KDO26761.1 - 0.08 11.8 0.0 0.2 10.5 0.0 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel RRM_1 PF00076.22 KDO26761.1 - 0.18 11.7 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dzip-like_N PF13815.6 KDO26762.1 - 7.9e-09 35.5 0.1 1.8e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Muted PF14942.6 KDO26762.1 - 0.19 12.1 0.5 0.27 11.6 0.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein tRNA-synt_His PF13393.6 KDO26763.1 - 3.6e-46 157.9 5.8 6.3e-46 157.1 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 KDO26763.1 - 1.8e-36 125.8 13.1 3.6e-36 124.8 13.1 1.4 1 0 0 1 1 1 1 Aromatic amino acid lyase HGTP_anticodon PF03129.20 KDO26763.1 - 1.6e-13 50.6 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KDO26763.1 - 0.00015 21.4 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KDO26763.1 - 0.00041 19.5 0.1 0.0012 18.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF5624 PF18538.1 KDO26763.1 - 0.1 12.7 0.0 0.42 10.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) AMP-binding PF00501.28 KDO26765.1 - 2.7e-78 263.5 0.1 3.6e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KDO26765.1 - 7.6e-25 86.6 2.0 2e-24 85.3 2.0 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KDO26765.1 - 2.8e-21 76.2 2.8 3.5e-21 76.0 1.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pox_Ag35 PF03286.14 KDO26766.1 - 2.6 7.8 14.4 2.7 7.7 13.1 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Na_Ca_ex PF01699.24 KDO26767.1 - 6.5e-30 104.1 38.5 8.5e-16 58.3 16.2 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Thioredoxin_8 PF13905.6 KDO26768.1 - 9.1e-22 77.2 0.0 1.3e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO26768.1 - 2.4e-07 30.7 0.0 4.7e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO26768.1 - 0.00033 21.1 0.0 0.0005 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KDO26768.1 - 0.00034 20.5 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO26768.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin NADH_4Fe-4S PF10589.9 KDO26768.1 - 0.028 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region TraF PF13728.6 KDO26768.1 - 0.15 11.8 0.0 0.6 9.9 0.0 1.8 1 1 0 1 1 1 0 F plasmid transfer operon protein Methyltransf_3 PF01596.17 KDO26768.1 - 0.32 10.1 0.3 0.5 9.5 0.3 1.2 1 0 0 1 1 1 0 O-methyltransferase C2 PF00168.30 KDO26769.1 - 7.9e-13 48.6 0.0 6.1e-05 23.2 0.0 4.2 4 0 0 4 4 4 3 C2 domain C1_1 PF00130.22 KDO26769.1 - 3.3e-07 30.1 3.4 3.3e-07 30.1 3.4 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PRT_C PF08372.10 KDO26769.1 - 5.6e-05 22.9 1.2 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 KDO26769.1 - 8.4e-05 22.1 0.1 0.056 12.9 0.1 2.3 2 0 0 2 2 2 2 Plant protein of unknown function (DUF639) Reticulon PF02453.17 KDO26769.1 - 0.00088 19.3 3.1 0.026 14.5 0.2 2.5 2 0 0 2 2 2 2 Reticulon C1_2 PF03107.16 KDO26769.1 - 0.0035 17.6 1.1 0.0035 17.6 1.1 2.1 2 0 0 2 2 2 1 C1 domain SET PF00856.28 KDO26770.1 - 1.3e-10 41.9 0.0 2.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KDO26770.1 - 4.1e-09 37.2 0.2 1.1e-08 35.8 0.2 1.8 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding PfkB PF00294.24 KDO26772.1 - 3.1e-69 233.6 1.0 3.7e-69 233.3 1.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ank_4 PF13637.6 KDO26774.1 - 3.9e-27 94.3 6.2 9.9e-10 38.8 0.1 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26774.1 - 4.1e-27 94.6 7.1 2.3e-11 44.1 0.7 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO26774.1 - 9.9e-26 89.5 15.5 7.6e-10 38.9 0.8 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO26774.1 - 1.8e-22 78.7 15.9 4.4e-07 30.0 0.2 6.4 5 1 1 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KDO26774.1 - 2.5e-22 76.5 1.8 1.3e-05 25.2 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat WW PF00397.26 KDO26775.1 - 1.4e-08 34.6 0.0 3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 WW domain Lipase_chap PF03280.14 KDO26775.1 - 8.9e-05 22.5 7.7 0.00011 22.2 7.7 1.1 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein Med17 PF10156.9 KDO26775.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex WW PF00397.26 KDO26776.1 - 1.6e-07 31.3 0.7 1.6e-07 31.3 0.7 2.6 3 0 0 3 3 3 1 WW domain ERM PF00769.19 KDO26776.1 - 0.00073 19.4 19.4 0.00073 19.4 19.4 11.4 2 1 7 10 10 10 3 Ezrin/radixin/moesin family Filament PF00038.21 KDO26776.1 - 0.0017 18.0 25.3 0.0017 18.0 25.3 10.9 3 3 3 8 8 8 2 Intermediate filament protein Spc7 PF08317.11 KDO26776.1 - 0.0028 16.6 16.2 0.0028 16.6 16.2 12.5 4 3 7 13 13 13 6 Spc7 kinetochore protein ZapB PF06005.12 KDO26776.1 - 0.063 13.7 0.1 0.063 13.7 0.1 21.6 8 5 8 18 18 18 0 Cell division protein ZapB Peptidase_S28 PF05577.12 KDO26777.1 - 2e-87 293.8 3.8 3.8e-87 292.9 3.8 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 PAN_4 PF14295.6 KDO26777.1 - 3e-28 97.5 37.5 3.3e-09 36.5 5.5 4.9 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 KDO26777.1 - 3.3e-18 65.4 6.0 2.7e-05 24.0 0.4 4.3 2 1 2 4 4 4 3 PAN domain Abhydrolase_1 PF00561.20 KDO26777.1 - 6.2e-05 22.8 0.1 0.00017 21.4 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF5107 PF17128.4 KDO26777.1 - 0.00094 18.4 0.1 7.6 5.6 0.1 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF5107) Peptidase_S9 PF00326.21 KDO26777.1 - 0.0084 15.6 0.6 0.014 14.9 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PT PF04886.12 KDO26777.1 - 0.0089 15.5 27.9 0.0089 15.5 27.9 4.6 3 1 1 4 4 4 1 PT repeat Glyco_hyd_101C PF17451.2 KDO26777.1 - 0.13 12.5 1.3 54 4.1 0.0 3.6 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain MANEC PF07502.14 KDO26777.1 - 0.39 11.0 12.6 14 6.0 0.4 3.5 3 0 0 3 3 3 0 MANEC domain Peptidase_S28 PF05577.12 KDO26778.1 - 1.1e-89 301.2 0.7 1.5e-89 300.8 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PAN_4 PF14295.6 KDO26778.1 - 7.2e-28 96.3 31.7 5e-10 39.1 5.4 3.9 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KDO26778.1 - 8.8e-17 60.8 8.7 1.2e-05 25.1 0.3 3.5 2 1 1 3 3 3 3 PAN domain Abhydrolase_1 PF00561.20 KDO26778.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 KDO26778.1 - 8e-05 21.5 0.1 0.00013 20.7 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF5107 PF17128.4 KDO26778.1 - 0.0028 16.9 0.0 2.3 7.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF5107) Hydrolase_4 PF12146.8 KDO26778.1 - 0.032 13.5 0.1 0.073 12.3 0.1 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MANEC PF07502.14 KDO26778.1 - 0.077 13.3 12.8 3 8.2 0.4 3.5 3 0 0 3 3 3 0 MANEC domain Peptidase_S9 PF00326.21 KDO26778.1 - 0.097 12.1 1.0 0.23 10.9 0.3 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family TALPID3 PF15324.6 KDO26778.1 - 1.8 6.1 5.9 1.7 6.2 1.9 2.2 2 0 0 2 2 2 0 Hedgehog signalling target MMR_HSR1 PF01926.23 KDO26779.1 - 2.3e-06 27.6 0.0 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GBP PF02263.19 KDO26779.1 - 1.4e-05 24.5 0.1 3.7e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KDO26779.1 - 3.6e-05 23.9 0.6 0.00016 21.8 0.4 2.1 1 1 0 1 1 1 1 Dynamin family RHD3 PF05879.12 KDO26779.1 - 0.00091 17.5 0.3 0.0025 16.0 0.0 1.8 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) FeoB_N PF02421.18 KDO26779.1 - 0.034 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KDO26779.1 - 0.036 14.4 4.8 0.36 11.2 0.2 4.0 3 1 1 4 4 4 0 AAA ATPase domain FAD_SOX PF18371.1 KDO26779.1 - 0.083 13.3 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase AAA_29 PF13555.6 KDO26779.1 - 0.23 11.2 0.7 1 9.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain PAN_4 PF14295.6 KDO26780.1 - 3.8e-08 33.1 1.8 6.2e-08 32.4 1.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KDO26780.1 - 0.00088 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 PAN domain E_raikovi_mat PF06360.11 KDO26780.1 - 0.025 15.0 0.5 0.049 14.0 0.5 1.5 1 0 0 1 1 1 0 Euplotes raikovi mating pheromone UCH PF00443.29 KDO26781.1 - 3e-39 135.1 0.0 5.2e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO26781.1 - 5e-10 39.5 0.1 0.00031 20.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 KDO26781.1 - 0.044 13.1 0.6 0.094 12.1 0.6 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Cyt-b5 PF00173.28 KDO26782.1 - 1.9e-08 34.4 0.3 4e-08 33.3 0.2 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 KDO26784.1 - 5.8e-94 315.6 0.0 1.9e-72 244.5 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.17 KDO26784.1 - 3e-22 79.1 0.0 1.3e-21 77.1 0.0 2.2 1 1 0 1 1 1 1 MyTH4 domain Myosin_N PF02736.19 KDO26784.1 - 0.0025 17.6 0.1 0.0058 16.4 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KDO26784.1 - 0.005 17.1 0.0 0.039 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KDO26784.1 - 0.042 14.4 0.1 0.14 12.7 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KDO26784.1 - 0.043 14.2 0.1 0.043 14.2 0.1 4.4 4 1 0 4 4 4 0 AAA ATPase domain zf-LYAR PF08790.11 KDO26785.1 - 1.3e-14 53.8 5.9 4.7e-14 52.0 2.0 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger C1_4 PF07975.12 KDO26785.1 - 0.18 12.0 5.4 0.53 10.6 5.4 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_12 PF11331.8 KDO26785.1 - 1.2 9.0 3.8 2.7 7.9 3.8 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain IBR PF01485.21 KDO26785.1 - 1.5 9.1 8.4 3 8.1 8.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TMPIT PF07851.13 KDO26785.1 - 3.9 6.6 4.7 1.5 8.0 2.4 1.6 2 0 0 2 2 2 0 TMPIT-like protein V-ATPase_H_N PF03224.14 KDO26787.1 - 3.1e-44 151.5 0.0 2.5e-43 148.6 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KDO26787.1 - 2.4e-39 134.0 2.8 9.2e-38 129.0 0.4 2.8 2 1 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 KDO26787.1 - 1e-07 31.7 1.7 0.14 12.2 0.1 5.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO26787.1 - 1.1e-05 25.7 0.9 0.098 13.1 0.0 3.7 3 1 0 3 3 3 1 HEAT repeats DRIM PF07539.12 KDO26787.1 - 0.00062 18.2 1.1 0.0064 14.9 0.0 2.5 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 KDO26787.1 - 0.00089 19.3 0.2 9.6 6.8 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Arm_2 PF04826.13 KDO26787.1 - 0.06 12.8 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Armadillo-like HMG_box PF00505.19 KDO26788.1 - 3.6e-05 24.1 0.1 7.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box COG4 PF08318.12 KDO26789.1 - 7.1e-14 51.6 1.9 5.8e-13 48.6 0.1 2.7 2 1 1 3 3 3 1 COG4 transport protein RINT1_TIP1 PF04437.13 KDO26789.1 - 5.8e-10 38.7 0.7 9.1e-10 38.0 0.7 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family G_glu_transpept PF01019.21 KDO26790.1 - 1.2e-143 479.6 0.0 1.4e-143 479.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GSHPx PF00255.19 KDO26792.1 - 7.9e-22 76.9 0.0 1.4e-20 72.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione peroxidase NCA2 PF08637.10 KDO26793.1 - 1.5e-48 165.5 2.4 2.8e-48 164.5 2.4 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Xpo1 PF08389.12 KDO26794.1 - 2.3e-07 31.0 1.4 1.8e-05 24.8 0.0 4.0 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 KDO26794.1 - 6.2e-07 29.2 0.0 1.4e-05 24.9 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KDO26794.1 - 1e-06 27.8 0.8 2.7e-06 26.5 0.3 2.0 3 0 0 3 3 3 1 Cse1 HEAT PF02985.22 KDO26794.1 - 0.18 12.2 1.5 26 5.4 0.1 5.0 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KDO26794.1 - 7 7.3 12.1 88 3.8 0.3 6.4 6 1 0 6 6 6 0 HEAT-like repeat Cpn60_TCP1 PF00118.24 KDO26795.1 - 1.7e-151 505.2 12.5 1.9e-151 505.1 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps52 PF04129.12 KDO26795.1 - 0.12 11.1 0.8 0.16 10.6 0.8 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family His_Phos_1 PF00300.22 KDO26796.1 - 1.8e-49 168.1 0.5 2e-49 167.9 0.5 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_17 PF00332.18 KDO26797.1 - 4.2e-07 29.9 1.4 4.2e-07 29.9 1.4 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 PAN_4 PF14295.6 KDO26797.1 - 4.8e-05 23.2 2.2 0.00012 21.9 2.2 1.7 1 0 0 1 1 1 1 PAN domain DUF4096 PF13340.6 KDO26798.1 - 0.054 13.7 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) Glyco_hydro_17 PF00332.18 KDO26799.1 - 7e-08 32.4 1.4 7e-08 32.4 1.4 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 Trypan_PARP PF05887.11 KDO26799.1 - 9e-06 25.7 13.8 1.5e-05 25.0 13.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PAN_4 PF14295.6 KDO26799.1 - 3.5e-05 23.6 1.6 0.0001 22.1 1.6 1.8 1 0 0 1 1 1 1 PAN domain TonB_N PF16031.5 KDO26799.1 - 0.93 10.0 29.2 1.4 9.5 29.2 1.1 1 0 0 1 1 1 0 TonB polyproline region FAM75 PF14650.6 KDO26799.1 - 1.9 8.0 14.8 2.6 7.5 14.8 1.1 1 0 0 1 1 1 0 FAM75 family Toxin_28 PF08115.11 KDO26799.1 - 7.4 6.5 8.3 3.7 7.5 5.4 1.9 2 0 0 2 2 2 0 SFI toxin family His_Phos_1 PF00300.22 KDO26800.1 - 2e-47 161.4 2.3 2.2e-47 161.3 2.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF962 PF06127.11 KDO26803.1 - 2.9 8.0 5.4 21 5.3 5.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) FKBP_C PF00254.28 KDO26804.1 - 4.5e-30 103.8 0.1 2.9e-29 101.2 0.1 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KDO26804.1 - 1.2e-15 58.0 0.0 1.2e-15 58.0 0.0 2.5 2 1 0 2 2 1 1 Nucleoplasmin-like domain YL1 PF05764.13 KDO26804.1 - 0.00051 20.2 20.6 0.00085 19.5 20.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 KDO26804.1 - 0.0056 15.0 13.5 0.0068 14.8 13.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 KDO26804.1 - 0.36 9.5 8.8 0.5 9.1 8.8 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 KDO26804.1 - 0.4 10.1 27.4 0.62 9.4 27.4 1.2 1 0 0 1 1 1 0 SDA1 GAGA_bind PF06217.12 KDO26804.1 - 1.1 9.4 7.6 1.7 8.9 7.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family LAP1C PF05609.12 KDO26804.1 - 2.2 7.3 11.6 2.9 6.9 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Gti1_Pac2 PF09729.9 KDO26804.1 - 2.8 8.0 7.0 4.7 7.3 7.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family ATP-synt_B PF00430.18 KDO26804.1 - 3.1 7.9 13.9 6.2 6.9 13.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HC2 PF07382.11 KDO26804.1 - 3.7 7.6 36.1 0.58 10.2 26.3 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Folliculin PF11704.8 KDO26804.1 - 4.5 7.1 5.0 7.3 6.4 5.0 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Nop14 PF04147.12 KDO26804.1 - 5.5 5.1 24.6 7.4 4.7 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family TraV PF09676.10 KDO26804.1 - 6.7 7.7 11.1 2.2 9.3 8.3 1.6 2 0 0 2 2 1 0 Type IV conjugative transfer system lipoprotein (TraV) GREB1 PF15782.5 KDO26804.1 - 7 3.6 8.0 8.4 3.4 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 KDO26804.1 - 7.1 6.4 17.2 13 5.5 17.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PX PF00787.24 KDO26805.1 - 3.4e-19 68.9 0.0 5.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 PX domain Peptidase_C92 PF05708.12 KDO26805.1 - 1.9e-06 28.1 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family FANCF PF11107.8 KDO26806.1 - 0.0024 17.2 11.7 0.0066 15.7 0.5 2.3 2 1 0 2 2 2 2 Fanconi anemia group F protein (FANCF) PSD2 PF07624.11 KDO26806.1 - 0.086 12.6 0.5 1.1 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) ADP_ribosyl_GH PF03747.14 KDO26806.1 - 1.3 8.7 8.8 5.7 6.6 8.6 2.1 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase Far-17a_AIG1 PF04750.14 KDO26807.1 - 4.8e-10 39.1 12.7 5.9e-10 38.8 12.7 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein His_Phos_1 PF00300.22 KDO26808.1 - 1e-45 155.8 0.0 1.3e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UPF0242 PF06785.11 KDO26809.1 - 0.053 13.6 7.6 0.092 12.8 7.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ARID PF01388.21 KDO26809.1 - 0.085 13.5 0.8 3.4 8.4 0.0 2.4 1 1 1 2 2 2 0 ARID/BRIGHT DNA binding domain FapA PF03961.13 KDO26809.1 - 5.2 5.6 5.5 7.2 5.1 5.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lzipper-MIP1 PF14389.6 KDO26810.1 - 0.03 14.6 0.5 14 6.0 0.5 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 KDO26810.1 - 0.11 12.8 0.4 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Pox_A_type_inc PF04508.12 KDO26810.1 - 0.3 11.0 2.0 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1295 PF06966.12 KDO26811.1 - 0.0045 16.5 2.3 0.0045 16.5 2.3 2.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KDO26811.1 - 0.0053 16.7 1.6 0.0071 16.3 0.2 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KDO26811.1 - 0.0056 15.5 0.3 0.0084 14.9 0.3 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Carn_acyltransf PF00755.20 KDO26813.1 - 3.3e-192 640.2 0.0 3.8e-192 640.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2839 PF10999.8 KDO26814.1 - 2.2 8.7 4.0 1.4 9.3 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) SKG6 PF08693.10 KDO26816.1 - 7.4 6.1 6.4 39 3.8 4.6 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ADK PF00406.22 KDO26817.1 - 4.6e-46 156.6 0.0 6.7e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase Peptidase_S66 PF02016.15 KDO26817.1 - 1.3e-22 80.2 0.0 2.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain AAA_17 PF13207.6 KDO26817.1 - 5.1e-22 78.8 0.0 1.1e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Peptidase_S66C PF17676.1 KDO26817.1 - 1.8e-18 67.2 0.0 4.3e-18 66.0 0.0 1.7 2 0 0 2 2 1 1 LD-carboxypeptidase C-terminal domain ADK_lid PF05191.14 KDO26817.1 - 6.3e-10 38.9 1.9 6.3e-10 38.9 1.9 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KDO26817.1 - 2.9e-05 24.3 0.0 5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO26817.1 - 0.0024 18.4 0.0 0.0045 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KDO26817.1 - 0.014 15.8 0.0 0.045 14.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TRP_2 PF08344.11 KDO26817.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Transient receptor ion channel II Cytidylate_kin PF02224.18 KDO26817.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Mg_chelatase PF01078.21 KDO26817.1 - 0.08 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HypA PF01155.19 KDO26817.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 KDO26817.1 - 0.86 9.4 7.5 0.14 11.9 0.5 3.1 4 0 0 4 4 4 0 A2L zinc ribbon domain RNase_Zc3h12a PF11977.8 KDO26818.1 - 7.2e-18 64.8 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 KDO26818.1 - 3.4e-05 23.5 0.5 9.5e-05 22.0 0.5 1.7 1 1 0 1 1 1 1 Protein-only RNase P Mitofilin PF09731.9 KDO26818.1 - 2.3 7.0 5.1 2.8 6.7 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BT1 PF03092.16 KDO26819.1 - 2.3e-12 45.9 1.4 2.3e-12 45.9 1.4 2.9 2 2 1 3 3 3 1 BT1 family PUCC PF03209.15 KDO26819.1 - 0.0035 16.4 0.2 0.0035 16.4 0.2 2.2 3 0 0 3 3 3 1 PUCC protein Peptidase_C2 PF00648.21 KDO26820.1 - 1e-40 139.6 0.0 1.1e-38 133.0 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 KDO26820.1 - 3.4e-06 27.4 0.0 7.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III DZR PF12773.7 KDO26820.1 - 0.0021 18.0 8.9 0.0021 18.0 8.9 5.5 2 2 1 3 3 3 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO26820.1 - 0.0091 15.7 3.9 0.0091 15.7 3.9 5.6 7 1 0 7 7 7 2 zinc-ribbon domain EPSP_synthase PF00275.20 KDO26822.1 - 6.2e-120 400.7 0.0 9.2e-120 400.1 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KDO26822.1 - 1e-96 323.1 0.0 1.8e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KDO26822.1 - 1.5e-38 133.3 0.0 2.5e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KDO26822.1 - 1e-24 87.5 0.0 4.8e-23 82.0 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KDO26822.1 - 1.5e-24 86.0 0.1 4.3e-24 84.6 0.1 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KDO26822.1 - 4.2e-10 39.8 0.3 2.1e-09 37.4 0.3 2.2 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KDO26822.1 - 3.6e-07 29.8 0.0 8.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH PF00465.19 KDO26822.1 - 9.3e-07 28.0 1.2 8.7e-06 24.8 1.2 2.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KDO26822.1 - 7.4e-06 26.1 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KDO26822.1 - 0.012 14.9 0.6 0.36 10.1 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IQ PF00612.27 KDO26825.1 - 7 6.7 11.1 7.5 6.6 0.3 3.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif SNF2_N PF00176.23 KDO26826.1 - 3.2e-54 184.0 0.5 2e-52 178.0 0.5 3.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO26826.1 - 1.8e-15 57.2 0.0 5.8e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 KDO26826.1 - 9.2e-06 26.4 0.2 9.2e-06 26.4 0.2 2.4 2 0 0 2 2 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4 PF00097.25 KDO26826.1 - 1.1e-05 25.2 9.4 1.1e-05 25.2 9.4 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO26826.1 - 2.5e-05 24.2 8.1 2.5e-05 24.2 8.1 3.1 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO26826.1 - 5.3e-05 23.0 6.4 5.3e-05 23.0 6.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO26826.1 - 5.8e-05 23.0 4.4 0.00014 21.8 3.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO26826.1 - 0.00021 21.1 9.0 0.00021 21.1 9.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO26826.1 - 0.001 19.4 7.9 0.001 19.4 7.9 2.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KDO26826.1 - 0.0023 18.0 8.6 0.0023 18.0 8.6 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING FYDLN_acid PF09538.10 KDO26826.1 - 0.0097 16.6 8.4 0.0097 16.6 8.4 4.9 4 1 2 6 6 4 1 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.7 KDO26826.1 - 0.015 15.6 4.9 0.015 15.6 4.9 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-C2HC_2 PF13913.6 KDO26826.1 - 0.027 14.3 0.2 0.098 12.6 0.2 2.0 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FAM176 PF14851.6 KDO26826.1 - 0.12 12.1 7.0 0.9 9.2 2.3 3.0 2 0 0 2 2 2 0 FAM176 family DUF3246 PF11596.8 KDO26826.1 - 1.4 8.3 9.5 1.9 7.9 2.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) RXT2_N PF08595.11 KDO26826.1 - 1.5 8.8 11.7 1.1 9.3 6.2 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-P11 PF03854.14 KDO26826.1 - 2.7 7.7 5.7 2.8 7.7 3.0 2.4 2 0 0 2 2 2 0 P-11 zinc finger TLP-20 PF06088.11 KDO26826.1 - 3.4 7.5 6.5 3.1 7.6 0.8 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FYVE PF01363.21 KDO26827.1 - 8.4e-06 25.8 8.3 2.6e-05 24.3 7.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger TF_Zn_Ribbon PF08271.12 KDO26827.1 - 0.0046 16.5 2.5 0.4 10.2 0.0 2.8 2 0 0 2 2 2 2 TFIIB zinc-binding FYVE_2 PF02318.16 KDO26827.1 - 0.0046 17.2 6.4 0.01 16.0 6.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zinc-ribbons_6 PF07191.12 KDO26827.1 - 3.1 7.9 7.9 17 5.5 0.5 2.5 2 1 1 3 3 3 0 zinc-ribbons LRR_4 PF12799.7 KDO26828.1 - 1.5e-15 57.1 18.7 3.5e-06 27.3 6.9 4.8 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26828.1 - 8.2e-11 41.5 26.6 1.7e-06 27.6 11.2 4.3 2 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KDO26828.1 - 2.8e-06 27.0 1.5 0.067 12.7 0.7 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KDO26828.1 - 2.6e-05 23.9 22.1 0.88 9.8 0.2 6.6 6 0 0 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.33 KDO26828.1 - 0.47 11.2 19.2 28 5.8 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat Ribonuclease_T2 PF00445.18 KDO26829.1 - 3.6e-28 99.0 2.3 4.7e-28 98.6 2.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Bestrophin PF01062.21 KDO26830.1 - 4.9e-23 81.9 1.7 6.5e-23 81.5 1.7 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2721 PF11026.8 KDO26830.1 - 0.023 14.6 1.2 0.063 13.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CHORD PF04968.12 KDO26831.1 - 5.7e-41 139.1 22.0 9.5e-21 74.3 4.8 2.4 2 0 0 2 2 2 2 CHORD BTK PF00779.19 KDO26831.1 - 0.0032 17.2 4.5 1.1 9.2 0.2 2.8 2 0 0 2 2 2 2 BTK motif bZIP_1 PF00170.21 KDO26832.1 - 5.5e-06 26.4 13.5 0.0029 17.7 0.1 2.9 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 KDO26832.1 - 0.00016 21.7 14.8 0.023 14.8 0.2 3.0 3 0 0 3 3 3 2 Basic region leucine zipper HR1 PF02185.16 KDO26832.1 - 1.5 9.0 9.9 0.27 11.4 1.0 2.8 3 0 0 3 3 3 0 Hr1 repeat PET117 PF15786.5 KDO26833.1 - 0.04 14.2 0.1 0.081 13.2 0.1 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF4537 PF15057.6 KDO26834.1 - 0.037 14.1 0.0 5.2 7.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 KDO26834.1 - 0.041 13.8 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor DUF5588 PF17826.1 KDO26834.1 - 0.32 9.8 2.0 10 4.9 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5588) Trypsin_2 PF13365.6 KDO26835.1 - 5.4e-12 46.8 0.0 1.1e-11 45.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO26835.1 - 0.029 14.2 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Trypsin Peptidase_S46 PF10459.9 KDO26835.1 - 0.24 10.0 0.1 0.34 9.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Endonuclease_NS PF01223.23 KDO26836.1 - 3.8e-30 105.4 0.1 5e-30 105.0 0.1 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KDO26836.1 - 0.015 15.4 0.4 0.035 14.2 0.4 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease RS4NT PF08071.12 KDO26836.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 RS4NT (NUC023) domain Endonuclease_NS PF01223.23 KDO26837.1 - 3e-32 112.3 0.0 3.9e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KDO26837.1 - 0.0026 17.9 0.2 0.0059 16.7 0.2 1.7 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 KDO26839.1 - 1.6e-32 113.1 0.0 2e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KDO26839.1 - 0.0027 17.8 0.2 0.0062 16.6 0.2 1.6 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease TPR_12 PF13424.6 KDO26840.1 - 6.5e-11 42.4 4.0 0.0002 21.6 0.4 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO26840.1 - 5.9e-07 29.2 0.4 0.014 15.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26840.1 - 0.0033 17.2 2.1 9 6.3 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26840.1 - 0.0045 17.1 4.4 2 8.8 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26840.1 - 0.023 15.0 0.2 4.8 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26840.1 - 0.034 14.3 1.4 16 5.9 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26840.1 - 0.035 14.8 1.1 0.53 11.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyl-CoA_dh_2 PF08028.11 KDO26840.1 - 0.042 14.1 0.5 0.062 13.6 0.5 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_10 PF13374.6 KDO26841.1 - 2e-52 173.7 23.7 1.3e-11 44.0 0.7 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26841.1 - 5e-50 167.7 18.4 1.8e-17 63.4 0.8 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26841.1 - 5.3e-16 57.4 16.1 0.00018 21.3 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26841.1 - 2.8e-13 48.9 15.5 0.028 14.5 0.1 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO26841.1 - 7.2e-13 47.8 13.4 0.0021 17.8 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 KDO26841.1 - 4.2e-10 39.3 7.5 0.039 14.6 0.3 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26841.1 - 2.3e-09 36.7 8.7 0.14 12.5 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26841.1 - 6.2e-08 33.2 14.0 0.1 13.3 0.1 5.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO26841.1 - 2.6e-06 27.0 10.6 0.0028 17.1 0.3 3.2 2 1 1 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 KDO26841.1 - 2.9e-06 27.6 11.3 4.9 8.2 0.2 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26841.1 - 0.00049 20.6 9.0 0.03 14.8 0.5 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26841.1 - 0.2 12.4 10.1 6.8 7.6 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26841.1 - 0.2 12.1 11.1 16 6.1 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KDO26841.1 - 0.26 11.6 4.0 27 5.2 0.1 4.2 3 3 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KDO26841.1 - 2.9 8.0 12.6 27 4.9 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 KDO26842.1 - 9.7e-133 443.0 0.4 1.6e-67 228.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KDO26842.1 - 6.1e-107 345.5 21.8 1.5e-09 37.2 0.1 12.6 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26842.1 - 4.2e-105 343.2 24.5 1.1e-12 47.4 0.0 12.3 2 2 10 12 12 12 12 TPR repeat TPR_2 PF07719.17 KDO26842.1 - 4e-80 257.6 21.8 4.6e-07 29.4 0.1 12.9 13 0 0 13 13 12 12 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26842.1 - 1.1e-74 240.5 17.3 2.6e-07 30.3 0.0 13.0 13 0 0 13 13 12 12 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26842.1 - 1e-61 200.9 24.7 2.7e-07 30.5 0.1 12.6 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26842.1 - 2.3e-55 180.6 8.9 3e-05 23.7 0.0 13.0 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26842.1 - 1.6e-43 147.0 10.1 8.5e-09 35.9 0.2 7.6 4 2 3 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26842.1 - 5.4e-42 141.9 33.6 3.4e-09 36.9 0.4 10.4 4 3 5 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 KDO26842.1 - 3.3e-39 130.2 13.0 5e-05 23.8 0.2 12.7 1 1 12 13 13 13 9 Tetratricopeptide repeat TPR_10 PF13374.6 KDO26842.1 - 6e-36 121.3 32.9 3.7e-05 23.4 0.0 12.1 11 1 1 12 12 12 10 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26842.1 - 4.1e-32 110.5 19.4 6.8e-07 29.7 1.8 8.7 2 2 9 11 11 11 10 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26842.1 - 2.9e-20 71.5 13.9 1 10.2 0.0 11.6 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 KDO26842.1 - 8.5e-16 57.9 7.0 0.036 14.2 0.0 6.9 4 1 5 9 9 9 6 Tetratricopeptide repeat TPR_15 PF13429.6 KDO26842.1 - 1e-13 51.2 5.7 0.00073 18.8 0.2 5.7 1 1 3 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 KDO26842.1 - 1e-12 48.7 3.2 0.15 12.5 0.0 5.5 2 1 3 5 5 5 4 Bacterial transcriptional activator domain NARP1 PF12569.8 KDO26842.1 - 1.8e-11 43.7 2.5 0.48 9.3 0.0 6.0 2 2 3 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KDO26842.1 - 5.7e-09 35.8 0.2 0.58 10.9 0.0 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO26842.1 - 2e-07 30.8 2.3 0.17 11.2 0.1 4.4 1 1 4 5 5 5 2 MalT-like TPR region PPR PF01535.20 KDO26842.1 - 3e-07 30.2 8.1 3.1 8.3 0.1 8.4 9 0 0 9 9 7 2 PPR repeat EST1_DNA_bind PF10373.9 KDO26842.1 - 3e-07 30.2 11.4 2.2 7.7 0.2 6.1 4 1 2 7 7 7 2 Est1 DNA/RNA binding domain TOM20_plant PF06552.12 KDO26842.1 - 4.6e-07 29.8 0.9 0.055 13.2 0.0 5.5 3 2 1 5 5 5 1 Plant specific mitochondrial import receptor subunit TOM20 FAT PF02259.23 KDO26842.1 - 2e-06 27.3 0.0 0.71 9.0 0.0 5.3 1 1 2 3 3 3 1 FAT domain TPR_21 PF09976.9 KDO26842.1 - 2.1e-05 24.3 7.6 0.043 13.5 0.5 4.5 1 1 2 4 4 4 2 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 KDO26842.1 - 8e-05 22.6 3.5 2.9 7.8 0.0 4.6 2 1 2 5 5 5 2 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 KDO26842.1 - 0.0001 22.5 12.6 0.69 10.2 0.1 6.1 2 2 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KDO26842.1 - 0.00031 20.3 14.9 0.53 9.6 0.3 5.3 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP T2SSF PF00482.23 KDO26842.1 - 0.0024 17.8 0.0 0.38 10.7 0.0 3.5 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F SHNi-TPR PF10516.9 KDO26842.1 - 0.0069 15.8 1.1 80 2.8 0.0 5.7 5 1 1 6 6 6 0 SHNi-TPR Fis1_TPR_C PF14853.6 KDO26842.1 - 0.011 15.8 0.8 1.5 9.0 0.0 3.9 4 0 0 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KDO26842.1 - 0.031 14.3 23.7 58 3.9 0.0 10.0 11 1 0 12 12 10 0 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 KDO26842.1 - 0.033 14.0 6.6 9.8 6.0 0.0 5.1 4 1 2 6 6 6 0 Domain of unknown function (DUF5113) ANAPC5 PF12862.7 KDO26842.1 - 0.15 12.2 0.7 5.3 7.2 0.0 3.6 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 KDO26842.1 - 0.41 10.3 15.0 13 5.5 0.1 7.1 4 3 6 10 10 9 0 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 KDO26842.1 - 0.72 9.8 7.1 16 5.5 0.1 4.8 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 DUF630 PF04783.12 KDO26842.1 - 1.3 9.3 4.2 14 5.9 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF630) Peptidase_S24 PF00717.23 KDO26843.1 - 8.1e-11 41.7 0.7 2e-10 40.5 0.2 1.9 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S24 PF00717.23 KDO26844.1 - 0.064 13.2 0.6 0.59 10.1 0.2 2.1 2 0 0 2 2 2 0 Peptidase S24-like DNA_pol_A PF00476.20 KDO26845.1 - 4.6e-78 262.9 0.6 1.7e-76 257.7 0.0 3.0 3 1 0 3 3 3 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KDO26845.1 - 4.3e-10 39.6 0.0 1.7e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease Nuc_sug_transp PF04142.15 KDO26846.1 - 0.35 10.0 0.6 0.74 8.9 0.6 1.5 2 0 0 2 2 2 0 Nucleotide-sugar transporter Choline_transpo PF04515.12 KDO26848.1 - 1.2e-65 221.9 27.5 1.2e-65 221.9 27.5 2.5 1 1 2 3 3 3 2 Plasma-membrane choline transporter MMR_HSR1 PF01926.23 KDO26851.1 - 5.4e-05 23.2 0.0 0.00072 19.6 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KDO26851.1 - 0.00018 21.6 0.0 0.00049 20.2 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 KDO26851.1 - 0.00036 19.9 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KDO26851.1 - 0.0013 17.0 0.0 0.0026 16.0 0.0 1.5 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) cNMP_binding PF00027.29 KDO26854.1 - 9.4e-21 73.7 0.2 2e-11 43.8 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain TPR_1 PF00515.28 KDO26854.1 - 3.4e-20 71.0 1.8 3.2e-08 33.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26854.1 - 3.7e-18 64.1 2.4 1.2e-06 28.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO26854.1 - 1.8e-13 49.5 1.5 2.2e-05 24.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO26854.1 - 8.6e-11 41.4 4.4 0.00016 21.8 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO26854.1 - 1.1e-10 41.0 1.3 5.1e-06 26.1 0.3 3.4 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 KDO26854.1 - 4.3e-10 39.6 0.7 0.0021 18.2 0.2 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26854.1 - 3.4e-07 30.5 2.4 0.00022 21.4 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO26854.1 - 4.5e-07 30.4 0.0 0.00033 21.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26854.1 - 8.5e-06 26.1 3.0 0.16 12.7 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO26854.1 - 9.8e-05 22.9 0.3 0.48 11.4 0.1 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO26854.1 - 0.00028 20.9 0.1 0.0064 16.5 0.0 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KDO26854.1 - 0.0015 18.3 1.6 4.9 7.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KDO26854.1 - 0.0081 16.2 0.3 0.043 13.8 0.1 2.0 1 1 1 2 2 2 1 Putative TPR-like repeat SHNi-TPR PF10516.9 KDO26854.1 - 0.0089 15.5 0.1 0.13 11.8 0.0 2.6 3 0 0 3 3 3 1 SHNi-TPR NARP1 PF12569.8 KDO26854.1 - 0.011 14.7 0.3 0.017 14.1 0.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KDO26854.1 - 0.021 14.8 0.9 13 6.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO26854.1 - 0.029 14.9 0.4 4.5 7.8 0.2 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO26854.1 - 0.042 14.1 2.2 1.9 8.8 0.8 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KDO26854.1 - 0.12 13.0 0.3 0.52 11.1 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 KDO26854.1 - 0.21 10.7 0.1 9.9 5.3 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat UT PF03253.14 KDO26855.1 - 2e-64 217.6 37.6 2.3e-64 217.3 37.6 1.0 1 0 0 1 1 1 1 Urea transporter 4F5 PF04419.14 KDO26857.1 - 1.4e-09 38.6 6.8 1.4e-09 38.6 6.8 2.3 1 1 0 2 2 2 1 4F5 protein family H-K_ATPase_N PF09040.11 KDO26857.1 - 0.66 10.5 11.5 0.81 10.2 2.1 2.2 2 0 0 2 2 2 0 Gastric H+/K+-ATPase, N terminal domain CEP76-C2 PF15627.6 KDO26859.1 - 1.6e-29 102.5 0.0 3.6e-29 101.4 0.0 1.6 2 0 0 2 2 2 1 CEP76 C2 domain Transglut_core3 PF13471.6 KDO26859.1 - 0.00044 20.1 0.9 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Transglut_core PF01841.19 KDO26859.1 - 0.0034 17.8 0.0 0.0099 16.3 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily DEAD_2 PF06733.15 KDO26860.1 - 7.6e-52 175.5 3.3 1.3e-51 174.7 3.3 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KDO26860.1 - 1.2e-50 172.1 0.0 5.8e-50 169.8 0.0 2.3 3 1 0 3 3 3 1 Helicase C-terminal domain DEAD PF00270.29 KDO26860.1 - 3.9e-05 23.5 0.0 0.024 14.4 0.0 3.1 3 1 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KDO26860.1 - 0.0001 22.4 0.7 0.018 15.1 0.0 3.5 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit PcfJ PF14284.6 KDO26860.1 - 0.0082 16.0 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 PcfJ-like protein FTHFS PF01268.19 KDO26863.1 - 3.6e-07 28.8 0.0 3.9e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase FTHFS PF01268.19 KDO26864.1 - 3e-43 147.9 1.9 3.4e-20 71.8 0.9 3.0 1 1 1 2 2 2 2 Formate--tetrahydrofolate ligase Aa_trans PF01490.18 KDO26866.1 - 6.5e-64 216.1 33.9 8.2e-64 215.8 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO26866.1 - 1e-10 41.2 32.5 9.3e-10 38.1 32.5 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family GPCR_chapero_1 PF11904.8 KDO26867.1 - 2.3e-30 106.1 0.0 1.2e-29 103.8 0.0 1.9 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KDO26867.1 - 4.7e-08 33.5 0.1 1.2e-07 32.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26867.1 - 1.3e-07 32.0 1.5 0.021 15.4 0.8 3.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO26867.1 - 1.9e-06 28.0 0.3 0.00089 19.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26867.1 - 6.3e-05 23.1 0.6 0.73 10.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat GOLD_2 PF13897.6 KDO26867.1 - 8e-05 23.2 0.3 0.0094 16.4 0.0 2.2 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking Ank PF00023.30 KDO26867.1 - 0.00093 19.5 1.5 1.8 9.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Med7 PF05983.11 KDO26868.1 - 1e-40 139.9 3.1 1.7e-39 135.9 0.1 2.2 1 1 1 2 2 2 2 MED7 protein E1-E2_ATPase PF00122.20 KDO26869.1 - 2.1e-45 154.4 0.5 2.1e-45 154.4 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KDO26869.1 - 2.1e-13 51.0 0.0 7.9e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO26869.1 - 2.3e-12 46.4 0.0 5.9e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO26869.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HD PF01966.22 KDO26871.1 - 6.9e-12 45.7 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 KDO26871.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HABP4_PAI-RBP1 PF04774.15 KDO26872.1 - 3.1e-05 24.8 0.6 3.5e-05 24.6 0.6 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Ion_trans PF00520.31 KDO26873.1 - 4.9e-33 114.4 43.9 4.7e-20 71.9 17.7 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_8 PF13833.6 KDO26873.1 - 0.0021 17.9 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO26873.1 - 0.011 15.2 0.1 0.028 14.0 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KDO26873.1 - 0.011 16.1 0.1 0.029 14.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KDO26873.1 - 0.085 12.8 0.3 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain DZR PF12773.7 KDO26874.1 - 0.0049 16.9 8.2 0.013 15.5 8.4 1.6 1 1 0 1 1 1 1 Double zinc ribbon zf-RING_10 PF16685.5 KDO26874.1 - 0.022 14.9 4.6 0.025 14.7 0.4 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 DHHC PF01529.20 KDO26874.1 - 1.3 9.2 5.1 11 6.1 0.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase tRNA-synt_1c PF00749.21 KDO26875.1 - 5.7e-06 25.5 0.0 6e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain APH PF01636.23 KDO26875.1 - 0.19 11.6 0.0 0.19 11.6 0.0 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 KDO26877.1 - 6.3e-35 119.6 14.3 2.9e-10 40.6 0.1 5.7 3 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO26877.1 - 1.4e-25 89.3 9.6 2.6e-06 27.9 0.0 8.5 4 4 5 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO26877.1 - 7.5e-24 83.1 16.9 0.00085 19.7 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 KDO26877.1 - 3.5e-21 73.0 4.6 0.0091 16.4 0.0 9.9 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KDO26877.1 - 2.1e-20 72.5 12.2 1.3e-05 25.4 0.0 8.7 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO26877.1 - 5.8e-08 32.3 0.0 9.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO26877.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.20 KDO26878.1 - 7.9e-10 38.7 0.0 5.8e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 KDO26878.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KDO26879.1 - 1e-19 70.8 24.1 2.7e-11 43.0 2.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO26879.1 - 6e-09 35.3 20.2 7.9e-08 31.6 2.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 KDO26879.1 - 0.024 15.0 4.7 0.11 12.8 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Ycf70 PF17382.2 KDO26879.1 - 0.26 11.7 1.1 1.2 9.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized Ycf70-like Pkinase PF00069.25 KDO26880.1 - 7.5e-31 107.5 0.0 9.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO26880.1 - 6.2e-27 94.5 0.0 7.1e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO26880.1 - 9.2e-05 21.4 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO26880.1 - 0.0089 16.0 0.1 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO26880.1 - 0.052 12.8 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Sugar_tr PF00083.24 KDO26881.1 - 1.9e-31 109.5 24.7 1.4e-28 100.0 14.9 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO26881.1 - 3.3e-24 85.5 14.7 3.3e-24 85.5 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HIG_1_N PF04588.13 KDO26881.1 - 0.5 10.6 9.3 0.52 10.6 0.4 3.7 3 0 0 3 3 3 0 Hypoxia induced protein conserved region Ras PF00071.22 KDO26882.1 - 6.6e-54 181.9 0.0 7.6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO26882.1 - 4.6e-21 75.2 0.0 6.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO26882.1 - 2.3e-09 37.0 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO26882.1 - 0.00046 19.8 0.0 0.00092 18.8 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Cation_ATPase_C PF00689.21 KDO26883.1 - 1.6e-44 151.8 10.0 2.5e-44 151.2 5.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO26883.1 - 1.5e-30 106.0 11.3 7.5e-20 71.2 1.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 KDO26883.1 - 8.3e-19 67.5 0.1 1.6e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO26883.1 - 2e-15 57.7 0.1 1.4e-14 54.8 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO26883.1 - 1.6e-10 40.5 0.0 3.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO26883.1 - 0.00046 20.0 0.2 0.008 15.9 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP_TPR_like PF17004.5 KDO26884.1 - 2.2e-12 47.0 4.3 6.2e-12 45.6 4.3 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_19 PF14559.6 KDO26884.1 - 2.2e-08 34.5 35.5 0.00032 21.1 2.3 7.4 5 2 2 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO26884.1 - 7.7e-06 26.0 12.7 0.0064 16.7 2.9 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KDO26884.1 - 0.00018 22.0 39.3 0.06 14.2 0.7 9.2 6 2 4 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO26884.1 - 0.0068 16.4 20.2 1.1 9.5 0.5 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO26884.1 - 0.012 15.9 31.0 0.73 10.2 0.5 6.4 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO26884.1 - 0.021 14.8 7.0 0.066 13.3 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO26884.1 - 0.022 15.4 19.4 3.5 8.5 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KDO26884.1 - 0.033 14.7 7.0 0.099 13.1 0.7 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 KDO26884.1 - 1.3 9.9 27.2 3.5 8.5 0.7 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Ribosomal_L19 PF01245.20 KDO26885.1 - 4.8e-24 84.4 0.5 6.3e-24 84.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Proteasom_Rpn13 PF04683.13 KDO26887.1 - 6.3e-24 84.3 0.0 9.7e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KDO26887.1 - 1.4e-19 70.3 4.1 3.2e-19 69.1 2.1 2.3 2 0 0 2 2 2 1 UCH-binding domain RAP80_UIM PF18282.1 KDO26887.1 - 0.014 15.2 0.1 0.042 13.6 0.1 1.8 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif DNA_pol_phi PF04931.13 KDO26887.1 - 0.25 9.4 1.4 0.42 8.7 1.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi GET2 PF08690.10 KDO26887.1 - 3 7.4 10.9 0.12 12.0 2.6 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 PAC1 PF16094.5 KDO26888.1 - 0.088 12.0 0.1 0.34 10.0 0.0 1.8 1 1 1 2 2 2 0 Proteasome assembly chaperone 4 Choline_kinase PF01633.20 KDO26888.1 - 0.12 12.0 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase DNA_pol3_delta2 PF13177.6 KDO26890.1 - 6.1e-12 45.6 0.0 9.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KDO26890.1 - 9.2e-08 32.6 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO26890.1 - 0.00011 22.6 0.6 0.015 15.7 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KDO26890.1 - 0.00026 21.0 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KDO26890.1 - 0.0012 19.0 0.1 0.045 13.9 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 KDO26890.1 - 0.0032 18.0 0.0 0.0067 17.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Rep_fac_C PF08542.11 KDO26890.1 - 0.0044 17.4 0.1 0.012 16.0 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KDO26890.1 - 0.007 16.6 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KDO26890.1 - 0.013 15.3 0.1 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_24 PF13479.6 KDO26890.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KDO26890.1 - 0.041 13.5 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KDO26890.1 - 0.083 12.9 0.2 0.17 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO26890.1 - 0.091 12.5 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SPX PF03105.19 KDO26892.1 - 4.5e-16 59.7 19.9 2e-08 34.6 1.3 3.3 1 1 2 3 3 3 3 SPX domain MFS_1 PF07690.16 KDO26892.1 - 3.3e-15 55.9 14.8 4.5e-15 55.4 14.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO26892.1 - 1.3e-07 30.9 6.1 2e-07 30.2 6.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter CCDC154 PF15450.6 KDO26892.1 - 0.00099 17.8 2.6 0.0017 17.0 2.6 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 LRR_4 PF12799.7 KDO26893.1 - 0.013 15.9 0.4 0.7 10.4 0.1 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SDA1 PF05285.12 KDO26893.1 - 0.026 14.0 12.2 0.035 13.5 12.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KDO26893.1 - 0.038 12.2 13.9 0.052 11.8 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4614 PF15391.6 KDO26893.1 - 0.12 12.3 7.5 0.24 11.4 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDC45 PF02724.14 KDO26893.1 - 0.12 10.6 9.1 0.17 10.1 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Dsh_C PF12316.8 KDO26893.1 - 0.25 11.7 2.2 0.46 10.9 2.2 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DARPP-32 PF05395.12 KDO26893.1 - 0.36 11.0 9.9 0.64 10.2 9.9 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 CobT PF06213.12 KDO26893.1 - 0.38 10.1 13.7 0.67 9.3 13.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 KDO26893.1 - 1.3 7.5 9.2 0.69 8.4 7.3 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 KDO26893.1 - 5.1 5.1 9.4 8.7 4.3 9.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_28 PF00295.17 KDO26894.1 - 1.2e-91 307.2 17.8 1.3e-91 307.0 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 KDO26895.1 - 1.6e-77 260.7 17.7 1.9e-77 260.5 17.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4175 PF13779.6 KDO26896.1 - 7.2 4.4 5.4 29 2.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Arginase PF00491.21 KDO26897.1 - 5.1e-52 177.1 2.1 1.1e-51 176.1 2.1 1.5 1 1 0 1 1 1 1 Arginase family TPX2 PF06886.11 KDO26898.1 - 0.0025 18.0 19.0 0.005 17.0 19.0 1.5 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) ENOD93 PF03386.14 KDO26899.1 - 0.23 11.4 2.9 0.16 11.8 0.4 2.0 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein S10_plectin PF03501.15 KDO26901.1 - 4.2e-45 151.7 0.1 5e-45 151.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_L15e PF00827.17 KDO26902.1 - 3.5e-31 108.4 4.9 6.8e-31 107.5 4.9 1.5 1 0 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 KDO26902.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 UBA-like domain SOG2 PF10428.9 KDO26902.1 - 3.5 6.7 17.9 4.5 6.3 17.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L16 PF00252.18 KDO26903.1 - 1.9e-31 108.8 0.0 2.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e BET PF17035.5 KDO26904.1 - 1.2e-07 31.7 0.0 1.4e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Hydrophob_seed PF14547.6 KDO26904.1 - 0.028 14.6 0.2 0.029 14.6 0.2 1.1 1 0 0 1 1 1 0 Hydrophobic seed protein Tiam_CC_Ex PF18385.1 KDO26905.1 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Ricin_B_lectin PF00652.22 KDO26907.1 - 0.00027 21.2 0.9 0.0004 20.6 0.9 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26907.1 - 0.0041 17.8 0.5 0.011 16.5 0.5 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KDO26908.1 - 0.00012 22.4 0.3 0.00021 21.6 0.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26908.1 - 0.0057 17.4 0.1 0.013 16.2 0.1 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Mce4_CUP1 PF11887.8 KDO26909.1 - 0.13 11.7 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative GrpE PF01025.19 KDO26909.1 - 0.34 10.6 2.7 2.1 8.0 0.9 2.4 2 1 0 2 2 2 0 GrpE Ricin_B_lectin PF00652.22 KDO26910.1 - 3.1e-06 27.4 1.6 5.5e-06 26.6 1.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26910.1 - 0.00027 21.6 1.2 0.00052 20.7 0.1 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like G-patch PF01585.23 KDO26911.1 - 2.3e-17 62.6 0.1 3.5e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KDO26911.1 - 2e-07 31.0 0.1 2e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 G-patch domain PAN_4 PF14295.6 KDO26913.1 - 3.7e-28 97.2 36.7 3e-07 30.3 3.0 5.3 4 1 0 4 4 4 4 PAN domain COX5B PF01215.19 KDO26913.1 - 0.33 10.6 12.7 0.82 9.4 0.7 3.4 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Vb DUF4590 PF15257.6 KDO26913.1 - 5 7.1 21.2 0.15 11.9 1.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4590) LRR_4 PF12799.7 KDO26916.1 - 0.011 16.2 1.7 11 6.6 0.1 4.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO26916.1 - 0.052 13.1 0.2 0.12 11.8 0.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 KDO26916.1 - 0.5 10.2 3.7 47 3.9 0.2 3.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 KDO26916.1 - 0.86 9.8 4.4 12 6.2 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat ABC2_membrane PF01061.24 KDO26917.1 - 1.9e-37 128.7 28.3 3.1e-37 128.1 25.9 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KDO26917.1 - 1e-25 90.8 0.0 1.7e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO26917.1 - 1.7e-06 28.1 2.0 0.036 13.9 0.6 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO26917.1 - 0.00019 21.4 0.1 0.00079 19.4 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KDO26917.1 - 0.00093 18.9 1.5 0.0019 17.9 0.6 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 KDO26917.1 - 0.0015 17.9 9.8 0.0015 17.9 9.8 2.6 3 0 0 3 3 3 1 ABC-2 family transporter protein SMC_N PF02463.19 KDO26917.1 - 0.0021 17.5 0.4 0.6 9.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO26917.1 - 0.0032 17.9 0.1 0.0085 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KDO26917.1 - 0.018 15.5 0.2 0.2 12.1 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KDO26917.1 - 0.02 14.0 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KDO26917.1 - 0.028 14.4 0.4 2.8 7.9 0.3 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KDO26917.1 - 0.028 14.0 0.0 0.076 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO26917.1 - 0.033 14.4 1.0 0.058 13.6 1.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KDO26917.1 - 0.036 14.6 0.7 0.059 13.9 0.7 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO26917.1 - 0.054 13.2 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 KDO26917.1 - 0.068 12.1 0.2 0.068 12.1 0.2 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KDO26917.1 - 0.07 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KDO26917.1 - 0.078 12.6 1.0 0.17 11.5 1.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KDO26917.1 - 0.12 12.1 0.6 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO26917.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO26917.1 - 0.23 11.6 0.5 0.46 10.6 0.5 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ank_4 PF13637.6 KDO26918.1 - 5.7e-08 33.2 0.1 4.4e-07 30.3 0.0 2.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO26918.1 - 2.3e-07 31.3 0.1 1.6e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO26918.1 - 3.8e-05 23.9 0.6 0.13 12.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO26918.1 - 0.014 15.7 0.1 0.074 13.4 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO26918.1 - 0.027 15.0 0.0 0.98 10.2 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Cwf_Cwc_15 PF04889.12 KDO26918.1 - 0.16 11.7 12.2 0.24 11.1 12.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2607 PF10795.9 KDO26919.1 - 0.052 13.7 2.1 2.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2607) Peptidase_Mx PF15887.5 KDO26920.1 - 0.037 13.4 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase LRR_1 PF00560.33 KDO26920.1 - 0.053 14.1 0.1 21 6.2 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Sporozoite_P67 PF05642.11 KDO26922.1 - 2.4 6.1 3.6 3.3 5.7 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 KDO26922.1 - 5.6 6.9 15.7 6.7 6.6 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 KDO26923.1 - 0.59 10.3 4.5 22 5.5 0.7 3.2 3 0 0 3 3 3 0 Leucine Rich repeat DJ-1_PfpI PF01965.24 KDO26926.1 - 2.3e-21 76.3 0.0 2.8e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Pentapeptide_4 PF13599.6 KDO26928.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) LRR_4 PF12799.7 KDO26930.1 - 0.0034 17.7 0.4 3.9 8.0 0.0 4.3 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26930.1 - 0.037 13.8 0.4 0.24 11.2 0.0 2.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 KDO26930.1 - 0.082 13.0 0.1 29 5.1 0.0 3.6 2 0 0 2 2 2 0 Leucine Rich repeat KDZ PF18758.1 KDO26934.1 - 3e-20 72.8 0.0 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2012 PF09430.10 KDO26936.1 - 7.3e-20 71.3 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 KDO26936.1 - 9.5e-05 22.6 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KDO26936.1 - 0.0026 17.7 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain DUF4538 PF15061.6 KDO26936.1 - 0.052 13.3 0.5 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF2846 PF11008.8 KDO26936.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) DOT1 PF08123.13 KDO26937.1 - 1.8e-09 37.4 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Rsa3 PF14615.6 KDO26938.1 - 6.1e-13 48.1 0.1 1e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Nop PF01798.18 KDO26938.1 - 0.078 12.4 0.4 0.32 10.4 0.1 1.8 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin MIP-T3 PF10243.9 KDO26939.1 - 2.6e-82 272.2 1.5 6.1e-41 139.0 0.2 2.5 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 KDO26939.1 - 1.5e-34 119.2 9.7 1.5e-34 119.2 9.7 2.7 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region SelB-wing_1 PF09105.10 KDO26939.1 - 0.081 12.9 0.2 5.7 7.0 0.0 2.9 2 1 0 2 2 2 0 Elongation factor SelB, winged helix Nup88 PF10168.9 KDO26939.1 - 1 7.1 8.1 1.7 6.4 8.1 1.3 1 0 0 1 1 1 0 Nuclear pore component Peptidase_S26 PF10502.9 KDO26940.1 - 3.1e-09 36.8 0.0 1.2e-07 31.6 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KDO26940.1 - 1.6e-08 34.4 0.0 2.8e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like CLP_protease PF00574.23 KDO26941.1 - 5.7e-80 267.5 0.0 6.9e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF4225 PF13988.6 KDO26941.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) US22 PF02393.16 KDO26942.1 - 0.046 14.0 0.5 1.7 8.9 0.1 2.7 3 1 0 3 3 3 0 US22 like Beach PF02138.18 KDO26943.1 - 2.2e-66 224.1 0.0 3.2e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain EF-hand_7 PF13499.6 KDO26944.1 - 6.7e-14 52.1 6.9 7.7e-10 39.1 2.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO26944.1 - 1.2e-13 49.7 9.9 0.0013 18.5 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 KDO26944.1 - 3.5e-12 44.9 11.4 0.00054 19.3 1.1 4.7 5 0 0 5 5 5 4 EF hand DMRL_synthase PF00885.19 KDO26944.1 - 3.4e-11 43.2 0.3 5.9e-11 42.4 0.3 1.4 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase EF-hand_8 PF13833.6 KDO26944.1 - 6.3e-09 35.5 7.9 8.3e-06 25.6 2.4 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO26944.1 - 9.3e-06 24.9 11.4 0.067 12.7 1.2 4.5 4 0 0 4 4 4 3 EF hand UQ_con PF00179.26 KDO26945.1 - 3.7e-36 123.9 0.0 4.9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KDO26945.1 - 0.019 15.3 0.0 0.024 14.9 0.0 1.3 1 1 0 1 1 1 0 RWD domain NHL PF01436.21 KDO26947.1 - 6.6e-26 89.0 13.1 2.4e-07 30.4 0.0 8.5 8 1 0 8 8 8 5 NHL repeat SGL PF08450.12 KDO26947.1 - 2.5e-11 43.6 0.4 6.1e-06 26.0 0.1 2.7 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 KDO26947.1 - 0.0027 18.1 1.0 7.4 7.2 0.0 4.8 4 0 0 4 4 4 1 Low-density lipoprotein receptor repeat class B SBBP PF06739.11 KDO26947.1 - 0.018 15.0 5.5 0.69 10.0 0.1 4.6 4 0 0 4 4 4 0 Beta-propeller repeat Helveticin_J PF17312.2 KDO26947.1 - 0.14 11.2 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Bacteriocin helveticin-J NHL PF01436.21 KDO26948.1 - 2.8e-07 30.2 8.7 0.0014 18.5 1.2 4.9 5 0 0 5 5 5 4 NHL repeat LMF1 PF06762.14 KDO26949.1 - 2.5 7.1 5.5 3 6.9 5.5 1.2 1 0 0 1 1 1 0 Lipase maturation factor MRP-L27 PF09809.9 KDO26950.1 - 5.8e-16 58.3 0.0 7.3e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 GBP PF02263.19 KDO26951.1 - 1.8e-67 227.4 0.0 3.3e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KDO26951.1 - 1.5e-26 93.5 25.6 1.1e-25 90.6 25.6 2.0 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Filament PF00038.21 KDO26951.1 - 0.0077 15.8 17.0 0.0077 15.8 17.0 3.0 1 1 2 3 3 3 1 Intermediate filament protein MMR_HSR1 PF01926.23 KDO26951.1 - 0.054 13.6 0.0 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO26951.1 - 0.19 11.6 1.7 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Kinesin_assoc PF16183.5 KDO26951.1 - 0.96 9.6 8.0 3 8.0 8.0 1.8 1 0 0 1 1 1 0 Kinesin-associated Dynamin_N PF00350.23 KDO26951.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.0 3 1 0 3 3 3 0 Dynamin family DUF3450 PF11932.8 KDO26951.1 - 4.1 6.6 23.2 7 5.9 17.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.11 KDO26951.1 - 7.2 6.1 16.5 0.22 11.1 8.8 2.1 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Peptidase_C54 PF03416.19 KDO26952.1 - 3.3e-79 266.2 0.0 3.8e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 KDO26952.1 - 0.03 13.8 0.0 0.096 12.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C78 zf-C2H2_6 PF13912.6 KDO26953.1 - 0.097 12.7 0.1 0.097 12.7 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KDO26953.1 - 0.45 11.5 0.2 0.45 11.5 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger LRR_4 PF12799.7 KDO26954.1 - 7.9e-11 42.0 8.8 5.2e-05 23.5 0.7 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO26954.1 - 5.3e-10 39.1 1.7 8.2e-10 38.5 1.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KDO26954.1 - 7.7e-05 22.4 3.5 7.7e-05 22.4 3.5 3.4 4 0 0 4 4 4 1 Leucine rich repeat Tropomodulin PF03250.14 KDO26954.1 - 0.06 13.4 1.0 0.16 12.1 1.0 1.7 1 0 0 1 1 1 0 Tropomodulin PIH1_CS PF18201.1 KDO26954.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 PIH1 CS-like domain LRR_1 PF00560.33 KDO26954.1 - 0.27 11.9 5.6 12 6.9 0.2 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat Homeobox_KN PF05920.11 KDO26955.1 - 7.4e-14 51.4 0.4 1.3e-13 50.6 0.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KDO26955.1 - 1.6e-08 34.2 0.1 3.1e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain DUF4419 PF14388.6 KDO26956.1 - 1.3e-103 346.6 0.0 1.5e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) MAPKK1_Int PF08923.10 KDO26957.1 - 2.5e-20 72.5 0.0 2.8e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting EXS PF03124.14 KDO26958.1 - 2.4e-65 221.1 6.3 2.7e-65 220.9 6.3 1.0 1 0 0 1 1 1 1 EXS family LRR_4 PF12799.7 KDO26959.1 - 4.1e-05 23.9 1.8 0.037 14.5 0.0 4.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO26959.1 - 0.0011 18.8 0.7 0.72 10.1 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 KDO26959.1 - 0.34 11.6 4.4 24 6.0 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO26959.1 - 0.42 10.4 2.1 20 5.0 0.1 3.9 4 1 0 4 4 4 0 Leucine rich repeat VPS9 PF02204.18 KDO26960.1 - 2.2e-09 37.4 0.0 6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RRN3 PF05327.11 KDO26960.1 - 0.13 10.7 0.3 0.2 10.1 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S9 PF00326.21 KDO26962.1 - 1.6e-23 83.3 0.1 8.4e-22 77.7 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO26962.1 - 5.7e-06 25.8 0.1 0.00015 21.1 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO26962.1 - 1.7e-05 24.6 0.1 0.0011 18.6 0.2 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold PD40 PF07676.12 KDO26962.1 - 0.015 15.2 0.2 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DLH PF01738.18 KDO26962.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Tim17 PF02466.19 KDO26963.1 - 6.7e-16 58.7 5.9 8.8e-16 58.3 5.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EF-hand_7 PF13499.6 KDO26965.1 - 6.4e-28 97.0 12.0 2e-15 57.0 4.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO26965.1 - 2.1e-26 89.4 12.2 6.1e-09 34.8 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO26965.1 - 5.1e-21 72.8 9.2 3.4e-06 26.6 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KDO26965.1 - 2.2e-20 72.2 12.1 2.1e-13 49.9 1.1 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KDO26965.1 - 9.2e-16 57.9 1.7 1e-06 29.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO26965.1 - 2.3e-14 52.1 6.2 1.3e-05 24.5 0.6 3.7 3 0 0 3 3 3 3 EF hand EF-hand_11 PF08976.11 KDO26965.1 - 9.4e-07 29.7 1.1 0.018 15.9 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KDO26965.1 - 5.1e-06 26.4 4.9 0.022 14.7 0.1 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KDO26965.1 - 1.4e-05 25.2 1.4 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain Staphylokinase PF02821.16 KDO26965.1 - 0.00018 21.9 1.5 0.007 16.8 0.2 2.8 1 1 2 3 3 3 1 Staphylokinase/Streptokinase family SPARC_Ca_bdg PF10591.9 KDO26965.1 - 0.0098 16.2 2.5 1.3 9.3 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3741 PF12552.8 KDO26965.1 - 0.012 15.6 1.5 0.26 11.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3741) Caleosin PF05042.13 KDO26965.1 - 0.013 15.4 1.2 2.9 7.8 0.0 3.0 1 1 1 3 3 3 0 Caleosin related protein SurA_N_2 PF13623.6 KDO26965.1 - 0.016 15.0 1.2 0.58 10.0 0.3 2.3 2 0 0 2 2 2 0 SurA N-terminal domain Leucyl-specific PF14795.6 KDO26965.1 - 0.052 13.6 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Gp-FAR-1 PF05823.12 KDO26965.1 - 0.052 13.9 1.7 0.35 11.2 0.1 2.3 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ribosomal_L11 PF00298.19 KDO26965.1 - 0.065 13.7 0.0 0.39 11.3 0.0 2.1 1 1 0 1 1 1 0 Ribosomal protein L11, RNA binding domain MgtE_N PF03448.17 KDO26965.1 - 0.94 10.1 5.3 0.32 11.6 1.0 2.2 3 0 0 3 3 2 0 MgtE intracellular N domain Ribosomal_S17e PF00833.18 KDO26966.1 - 1.5e-58 196.0 0.2 1.7e-58 195.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 tRNA_anti-codon PF01336.25 KDO26967.1 - 0.0019 18.2 0.9 0.0034 17.3 0.9 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF473 PF04322.12 KDO26967.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF473) Acetyltransf_13 PF13880.6 KDO26968.1 - 1.8e-25 88.7 0.0 4.5e-25 87.4 0.0 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KDO26968.1 - 2.3e-12 46.5 0.1 4.5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KDO26968.1 - 1.8e-06 28.2 0.0 4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO26968.1 - 3.3e-05 24.1 0.0 5.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO26968.1 - 4.2e-05 23.5 0.0 9.1e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO26968.1 - 0.038 14.1 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KDO26968.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ATP11 PF06644.11 KDO26969.1 - 4.8e-27 95.4 0.0 5.8e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Creatinase_N_2 PF16189.5 KDO26970.1 - 2e-44 151.5 0.0 9.9e-44 149.3 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KDO26970.1 - 4.3e-37 127.8 0.0 6.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KDO26970.1 - 3.4e-23 81.5 0.1 1.1e-22 79.8 0.1 2.0 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KDO26970.1 - 2.5e-20 73.5 0.6 3.3e-14 53.7 0.2 2.8 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain Erf4 PF10256.9 KDO26971.1 - 1e-05 25.6 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Cyt_bd_oxida_I PF01654.17 KDO26971.1 - 0.24 10.0 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Metallophos_2 PF12850.7 KDO26972.1 - 4.4e-24 85.5 0.1 5.4e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KDO26972.1 - 0.0011 19.5 0.4 0.14 12.7 0.4 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_9 PF14580.6 KDO26973.1 - 3.1e-13 49.6 5.5 6e-09 35.6 0.3 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KDO26973.1 - 3.8e-12 46.2 19.2 0.00013 22.2 2.4 4.3 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO26973.1 - 6.6e-10 38.6 19.4 3e-06 26.9 1.9 3.4 1 1 2 3 3 3 3 Leucine rich repeat ParB_C PF18064.1 KDO26973.1 - 0.089 13.0 0.4 0.2 11.8 0.4 1.6 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal LRR_6 PF13516.6 KDO26973.1 - 0.17 12.0 0.1 0.17 12.0 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat HABP4_PAI-RBP1 PF04774.15 KDO26973.1 - 9.2 7.1 8.8 4.7 8.1 1.5 2.5 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Cytochrom_B561 PF03188.16 KDO26974.1 - 2.6e-17 63.3 4.3 2.6e-17 63.3 4.3 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Trp_oprn_chp PF09534.10 KDO26974.1 - 0.01 15.7 1.8 0.017 14.9 1.0 1.7 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2516 PF10724.9 KDO26974.1 - 0.045 14.0 0.2 0.045 14.0 0.2 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2516) DUF3784 PF12650.7 KDO26974.1 - 0.076 13.2 14.0 0.17 12.1 0.5 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF3784) DUF4149 PF13664.6 KDO26974.1 - 0.077 13.3 7.4 2.4 8.5 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF2919 PF11143.8 KDO26974.1 - 1.5 9.1 8.2 0.54 10.6 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) Yip1 PF04893.17 KDO26974.1 - 1.5 8.5 13.7 69 3.1 13.7 2.6 1 1 0 1 1 1 0 Yip1 domain E1-E2_ATPase PF00122.20 KDO26974.1 - 4.8 6.7 5.6 6.9 6.2 0.0 2.8 3 0 0 3 3 3 0 E1-E2 ATPase RNA_pol_N PF01194.17 KDO26975.1 - 4.1e-31 107.1 1.0 4.7e-31 106.9 1.0 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KDO26975.1 - 0.019 15.2 0.7 0.027 14.7 0.7 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ORC_WH_C PF18137.1 KDO26976.1 - 1.9e-16 60.4 0.4 5.4e-12 46.0 0.4 2.6 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KDO26976.1 - 2e-16 60.1 0.5 3.5e-15 56.0 0.5 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus THP2 PF09432.10 KDO26976.1 - 0.47 10.5 3.1 3.8 7.6 0.1 3.5 3 1 0 4 4 4 0 Tho complex subunit THP2 SlyX PF04102.12 KDO26977.1 - 0.26 11.9 3.5 0.25 12.0 1.3 1.8 2 0 0 2 2 2 0 SlyX MIT PF04212.18 KDO26978.1 - 0.11 12.6 2.4 0.18 11.9 1.2 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PhnH PF05845.12 KDO26979.1 - 0.024 14.4 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) ANAPC4_WD40 PF12894.7 KDO26981.1 - 1.2e-06 28.7 0.7 0.81 10.0 0.0 3.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO26981.1 - 0.024 15.5 1.8 1.3 10.0 0.1 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat cNMP_binding PF00027.29 KDO26982.1 - 3.2e-11 43.2 0.0 9.8e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain zf-CCHC PF00098.23 KDO26982.1 - 0.11 12.6 0.7 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KDO26982.1 - 0.43 10.4 2.4 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Zinc knuckle Vps35 PF03635.17 KDO26983.1 - 2e-10 39.9 4.8 0.00012 20.7 1.7 2.9 3 0 0 3 3 3 3 Vacuolar protein sorting-associated protein 35 Acetyltransf_1 PF00583.25 KDO26984.1 - 1.2e-13 51.3 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO26984.1 - 1.3e-09 38.1 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO26984.1 - 3.4e-09 37.0 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO26984.1 - 4.5e-08 32.9 0.0 6.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KDO26984.1 - 0.003 17.7 0.1 0.0041 17.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO26984.1 - 0.0041 17.2 0.2 0.016 15.3 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SLD5_C PF16922.5 KDO26986.1 - 8.4e-13 48.3 0.0 1.8e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KDO26986.1 - 4.1e-06 27.2 1.2 7.5e-06 26.4 1.2 1.5 1 0 0 1 1 1 1 GINS complex protein DivIC PF04977.15 KDO26986.1 - 0.0047 16.7 0.9 0.013 15.2 0.9 1.8 1 1 0 1 1 1 1 Septum formation initiator Complex1_LYR_2 PF13233.6 KDO26986.1 - 0.02 15.6 0.4 0.047 14.4 0.4 1.7 1 0 0 1 1 1 0 Complex1_LYR-like DUF4795 PF16043.5 KDO26986.1 - 0.029 14.0 3.1 0.038 13.6 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) MtlR PF05068.12 KDO26986.1 - 0.047 13.7 1.2 0.075 13.0 1.2 1.3 1 0 0 1 1 1 0 Mannitol repressor Band_7 PF01145.25 KDO26987.1 - 4.3e-22 79.0 3.1 4.3e-22 79.0 3.1 1.6 2 1 0 2 2 2 1 SPFH domain / Band 7 family Myb_DNA-bind_3 PF12776.7 KDO26988.1 - 1.7e-16 60.9 0.2 2.9e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 KDO26988.1 - 0.076 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Myb_DNA-bind_4 PF13837.6 KDO26988.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Sulfate_transp PF00916.20 KDO26989.1 - 1.2e-19 70.4 24.2 1.6e-19 69.9 24.2 1.1 1 0 0 1 1 1 1 Sulfate permease family Sulfate_transp PF00916.20 KDO26990.1 - 1.1e-24 86.9 22.7 1.6e-24 86.4 22.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KDO26990.1 - 4.2e-10 39.3 0.0 8.2e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KDO26990.1 - 1.3e-09 38.0 0.0 3.4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain BRCA-2_OB1 PF09103.10 KDO26991.1 - 5.2e-18 65.2 0.0 1.2e-16 60.8 0.0 2.9 2 1 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 KDO26991.1 - 5.1e-15 54.8 7.8 0.027 14.2 0.0 7.2 7 0 0 7 7 7 4 BRCA2 repeat BRCA-2_helical PF09169.10 KDO26991.1 - 3.6e-13 49.6 0.0 6.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical BPL_LplA_LipB PF03099.19 KDO26992.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family DUF98 PF01947.16 KDO26993.1 - 1.4e-19 70.5 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase Ribosomal_L34 PF00468.17 KDO26994.1 - 1.3e-17 63.5 8.6 2e-17 62.9 8.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DPM2 PF07297.12 KDO26995.1 - 3.7e-32 110.4 3.7 4.2e-32 110.3 3.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KDO26995.1 - 1.3e-07 31.6 0.7 1.5e-07 31.4 0.7 1.0 1 0 0 1 1 1 1 PIG-P Tom22 PF04281.13 KDO26996.1 - 1.1e-06 28.5 0.2 1.5e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Ricin_B_lectin PF00652.22 KDO26997.1 - 2e-22 79.8 1.8 8.7e-11 42.2 0.3 3.2 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KDO26997.1 - 7.4e-07 28.9 2.2 0.052 13.1 0.0 3.6 4 0 0 4 4 4 2 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 KDO26997.1 - 0.00011 22.8 2.0 0.033 14.9 0.0 3.8 2 1 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like GspH PF12019.8 KDO26997.1 - 0.0093 16.4 0.0 0.35 11.3 0.0 2.6 2 0 0 2 2 2 1 Type II transport protein GspH Ricin_B_lectin PF00652.22 KDO26998.1 - 1.9e-29 102.5 21.1 1e-13 51.6 1.7 3.6 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26998.1 - 4.6e-11 43.3 19.3 0.00022 21.9 1.7 5.1 3 2 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO26998.1 - 0.00014 21.4 1.2 0.03 13.9 0.0 2.8 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain Ricin_B_lectin PF00652.22 KDO26999.1 - 8e-24 84.3 20.1 1.6e-12 47.8 6.7 3.3 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO26999.1 - 9.8e-10 39.0 21.3 0.0002 22.0 4.0 4.8 3 2 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO26999.1 - 0.0065 16.1 9.4 2.1 7.9 0.1 3.4 1 1 1 3 3 3 3 Cytolethal distending toxin A/C domain DUF4434 PF14488.6 KDO26999.1 - 0.013 15.5 1.1 0.021 14.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) THF_DHG_CYH PF00763.23 KDO26999.1 - 0.055 13.7 0.2 0.47 10.7 0.0 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ubiquitin_2 PF14560.6 KDO26999.1 - 0.36 11.3 1.3 2.5 8.6 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain ABC2_membrane PF01061.24 KDO27000.1 - 6.3e-29 100.9 7.2 1e-28 100.2 7.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO27000.1 - 1.4e-10 41.9 0.0 3.8e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KDO27000.1 - 0.0012 18.8 0.8 0.0052 16.7 0.1 2.0 1 1 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KDO27000.1 - 0.0012 18.0 3.7 0.0027 16.9 3.7 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KDO27000.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO27000.1 - 0.021 15.3 0.1 0.047 14.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO27000.1 - 0.028 14.7 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KDO27000.1 - 0.035 13.9 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO27000.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO27000.1 - 0.066 13.6 0.4 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KDO27000.1 - 0.082 13.2 0.1 0.48 10.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KDO27000.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF5360 PF17314.2 KDO27000.1 - 0.17 11.9 2.8 1.5 8.9 1.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5360) AAA_18 PF13238.6 KDO27000.1 - 0.2 12.2 0.0 0.59 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 KDO27000.1 - 0.67 10.2 5.2 1.2 9.4 3.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Ferritin_2 PF13668.6 KDO27001.1 - 0.03 14.5 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain GIT_CC PF16559.5 KDO27001.1 - 0.045 13.6 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syntaxin-6_N PF09177.11 KDO27001.1 - 0.063 13.8 0.1 0.24 12.0 0.0 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 KDO27001.1 - 0.29 11.2 1.4 0.89 9.7 0.0 2.3 3 0 0 3 3 3 0 bZIP transcription factor SDF PF00375.18 KDO27002.1 - 4.9e-98 328.7 32.7 5.6e-98 328.5 32.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FYVE PF01363.21 KDO27003.1 - 2.3e-05 24.4 6.2 4.7e-05 23.5 6.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 KDO27003.1 - 0.011 15.4 2.1 0.021 14.5 2.1 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Pkinase PF00069.25 KDO27005.1 - 5.5e-51 173.5 0.0 7.8e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27005.1 - 2.2e-47 161.5 0.0 2.9e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase T4SS_CagC PF16943.5 KDO27005.1 - 0.0018 18.4 0.1 0.017 15.3 0.1 2.2 2 0 0 2 2 2 1 Cag pathogenicity island, type IV secretory system Pkinase_fungal PF17667.1 KDO27005.1 - 0.0041 16.0 0.1 0.0065 15.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO27005.1 - 0.019 14.3 0.0 0.08 12.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KDO27005.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO27005.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF155 PF02582.14 KDO27006.1 - 6.5e-24 85.0 0.5 1.4e-23 83.9 0.5 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Acyltransferase PF01553.21 KDO27007.1 - 4.8e-07 29.5 0.0 2.1e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase LSM PF01423.22 KDO27008.1 - 7e-14 51.3 0.1 8.9e-14 50.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO27008.1 - 0.00013 22.1 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Bin3 PF06859.12 KDO27009.1 - 1.2e-37 128.8 0.0 2e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KDO27009.1 - 1.5e-10 41.1 0.0 7.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27009.1 - 6.3e-10 39.7 0.1 3.6e-08 34.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO27009.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27009.1 - 2.1e-08 34.8 0.0 8.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO27009.1 - 3.3e-06 27.7 0.0 0.007 17.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_9 PF08003.11 KDO27009.1 - 0.00073 18.6 0.0 0.75 8.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 KDO27009.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KDO27009.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 KDO27009.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KDO27009.1 - 0.054 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KDO27009.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KDO27009.1 - 0.15 12.0 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SRP68 PF16969.5 KDO27010.1 - 1.3e-116 390.9 13.7 3e-116 389.7 13.7 1.5 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 Herpes_U44 PF04533.13 KDO27010.1 - 0.1 12.2 0.3 0.65 9.6 0.0 2.3 3 1 0 3 3 3 0 Herpes virus U44 protein TPR_2 PF07719.17 KDO27010.1 - 8.6 6.8 13.0 4.1 7.7 1.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C69 PF03577.15 KDO27012.1 - 4.1e-40 138.0 0.0 1.1e-39 136.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C69 EMG1 PF03587.14 KDO27013.1 - 4.3e-61 206.0 0.0 5.1e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pkinase_Tyr PF07714.17 KDO27015.1 - 3.2e-14 52.9 0.0 4.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO27015.1 - 5e-14 52.3 0.0 7.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KDO27016.1 - 1.8e-19 70.1 14.1 4.1e-05 24.1 0.2 7.1 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27016.1 - 6e-10 39.5 28.1 0.0096 16.5 0.1 8.8 7 2 6 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27016.1 - 1.2e-08 35.1 13.1 0.22 11.9 0.1 8.5 5 3 4 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27016.1 - 6.3e-07 29.2 21.1 6.1 7.8 0.0 11.1 12 1 1 13 13 13 1 Ankyrin repeat DUF4287 PF14117.6 KDO27016.1 - 0.0056 16.8 2.1 0.27 11.4 0.3 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4287) SCO1-SenC PF02630.14 KDO27017.1 - 6.8e-37 126.4 0.0 1.2e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Fer4 PF00037.27 KDO27018.1 - 3.4e-14 51.9 17.5 1.4e-08 34.1 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KDO27018.1 - 5.5e-13 49.3 10.4 8.8e-13 48.6 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KDO27018.1 - 8.3e-11 42.7 5.4 5e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KDO27018.1 - 4.2e-10 39.6 3.4 0.00014 21.9 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KDO27018.1 - 7.9e-09 35.6 10.2 1.3e-08 34.8 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KDO27018.1 - 1.7e-08 34.5 21.7 3.7e-06 26.9 12.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KDO27018.1 - 2.4e-07 30.5 17.8 0.00033 20.6 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KDO27018.1 - 8.3e-07 28.7 12.1 0.0023 17.9 2.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KDO27018.1 - 3e-06 27.6 21.0 0.00044 20.6 12.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KDO27018.1 - 5.5e-06 26.5 11.4 0.0003 21.1 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KDO27018.1 - 0.00034 21.1 11.5 0.038 14.5 12.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KDO27018.1 - 0.011 16.2 14.7 0.59 10.7 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KDO27018.1 - 0.013 15.7 5.9 0.46 10.8 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KDO27018.1 - 0.026 14.7 8.5 1.7 8.9 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KDO27018.1 - 0.14 13.2 16.3 0.29 12.2 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KDO27018.1 - 0.26 11.4 6.1 2 8.6 0.9 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KDO27018.1 - 0.58 11.0 11.7 2.3 9.1 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain DcpS_C PF11969.8 KDO27019.1 - 5.7e-28 97.7 0.1 1.3e-27 96.5 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KDO27019.1 - 4.5e-12 46.7 0.0 8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Ephrin_rec_like PF07699.13 KDO27020.1 - 0.00067 19.4 333.2 0.028 14.2 1.7 30.2 10 8 17 30 30 30 22 Putative ephrin-receptor like Sp38 PF07354.12 KDO27020.1 - 0.0013 18.2 6.3 0.0013 18.2 6.3 18.6 5 5 12 21 21 21 3 Zona-pellucida-binding protein (Sp38) PGAP1 PF07819.13 KDO27020.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Exo_endo_phos PF03372.23 KDO27021.1 - 2.3e-71 240.0 5.8 5.2e-71 238.8 5.8 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family fn3 PF00041.21 KDO27021.1 - 3e-12 46.7 0.0 6.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO27021.1 - 5.2e-06 26.9 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain LRR_9 PF14580.6 KDO27022.1 - 1.3e-14 54.0 0.0 2.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KDO27022.1 - 7.5e-11 41.6 0.3 8.3e-07 28.7 0.1 3.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO27022.1 - 4.8e-06 26.8 0.3 0.059 13.8 0.0 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO27023.1 - 2.7e-11 43.1 2.7 2.6e-07 30.3 0.9 3.3 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO27023.1 - 1.3e-08 35.0 6.3 5.3e-05 23.5 0.2 3.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO27023.1 - 2.8e-07 30.9 12.5 4.5e-07 30.2 12.5 1.3 1 0 0 1 1 1 1 LNR domain LRR_9 PF14580.6 KDO27023.1 - 0.0011 18.6 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KDO27023.1 - 0.049 14.2 2.2 37 5.4 0.0 4.2 3 2 1 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO27024.1 - 1.1e-08 34.7 5.0 0.00046 19.9 0.2 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO27024.1 - 5.4e-05 23.5 0.1 0.089 13.2 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO27024.1 - 0.00052 20.4 13.6 0.00052 20.4 13.6 2.9 3 0 0 3 3 3 1 LNR domain CFC PF09443.10 KDO27024.1 - 0.0042 16.9 0.3 0.013 15.3 0.3 1.8 1 0 0 1 1 1 1 Cripto_Frl-1_Cryptic (CFC) ABC_tran PF00005.27 KDO27025.1 - 7.1e-12 46.0 0.0 1e-11 45.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KDO27025.1 - 1.4e-06 28.4 0.1 1.6e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO27025.1 - 0.00086 19.0 0.2 0.0016 18.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO27025.1 - 0.0067 16.5 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KDO27025.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KDO27025.1 - 0.02 14.5 0.1 0.067 12.8 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KDO27025.1 - 0.028 14.8 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KDO27025.1 - 0.038 14.5 0.0 0.11 13.0 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO27025.1 - 0.043 14.0 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KDO27025.1 - 0.053 13.2 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KDO27025.1 - 0.063 12.5 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Guanylate_kin PF00625.21 KDO27025.1 - 0.075 12.7 0.1 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 Guanylate kinase AAA_35 PF14516.6 KDO27025.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.6 KDO27025.1 - 0.15 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KDO27026.1 - 4.4e-37 127.5 22.3 6.2e-37 127.1 22.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO27026.1 - 4.1e-27 95.4 0.0 7.2e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO27026.1 - 6.3e-09 36.1 0.2 0.00035 20.5 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO27026.1 - 4.5e-05 23.4 0.1 8.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KDO27026.1 - 0.0033 16.6 18.1 0.0033 16.6 18.1 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KDO27026.1 - 0.0034 17.1 0.2 0.0076 16.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO27026.1 - 0.0048 17.3 0.0 0.0093 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KDO27026.1 - 0.04 13.4 0.1 1.4 8.3 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KDO27026.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KDO27026.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TrmO PF01980.16 KDO27027.1 - 3.8e-38 130.4 0.0 1.7e-37 128.3 0.0 2.0 2 0 0 2 2 2 1 tRNA-methyltransferase O Histone_HNS PF00816.21 KDO27027.1 - 0.052 14.4 0.5 0.12 13.2 0.5 1.7 1 1 0 1 1 1 0 H-NS histone family ABC2_membrane PF01061.24 KDO27028.1 - 3.8e-37 127.8 22.4 7.1e-37 126.9 22.4 1.4 1 1 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO27028.1 - 8.2e-27 94.4 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO27028.1 - 2.3e-08 34.2 0.1 0.00065 19.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO27028.1 - 6.8e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KDO27028.1 - 0.00016 20.9 20.9 0.00016 20.9 20.9 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_30 PF13604.6 KDO27028.1 - 0.0019 17.9 0.0 0.0075 16.0 0.0 1.9 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KDO27028.1 - 0.0025 17.3 0.0 0.13 11.7 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO27028.1 - 0.0028 18.1 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO27028.1 - 0.003 17.3 0.1 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 KDO27028.1 - 0.078 12.6 0.1 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KDO27028.1 - 0.082 12.5 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO27028.1 - 0.19 12.2 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KDO27028.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase ABC2_membrane_2 PF12679.7 KDO27028.1 - 0.22 10.8 11.7 0.46 9.7 11.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 KDO27029.1 - 1.5e-23 83.8 0.0 2.3e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KDO27029.1 - 1.9e-16 60.1 7.1 2.7e-16 59.7 7.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KDO27029.1 - 2.4e-08 34.2 0.0 0.00051 19.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO27029.1 - 2.7e-05 24.1 0.2 4.5e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KDO27029.1 - 0.00054 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO27029.1 - 0.00074 19.2 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KDO27029.1 - 0.00085 18.8 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KDO27029.1 - 0.0038 17.2 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain Dynamin_N PF00350.23 KDO27029.1 - 0.006 16.7 0.1 0.028 14.5 0.0 2.2 2 1 0 2 2 2 1 Dynamin family PduV-EutP PF10662.9 KDO27029.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KDO27029.1 - 0.019 15.3 0.0 0.06 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO27029.1 - 0.022 15.3 0.0 0.05 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KDO27029.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 KDO27029.1 - 0.072 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_35 PF14516.6 KDO27029.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 KDO27029.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO27029.1 - 0.14 12.3 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KDO27029.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KDO27030.1 - 3.5e-15 56.0 8.6 3.5e-15 56.0 8.6 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KDO27030.1 - 0.00058 19.1 9.2 0.00059 19.0 9.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KDO27030.1 - 0.0017 17.7 1.7 0.0019 17.5 1.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Solute_trans_a PF03619.16 KDO27033.1 - 4.7e-64 216.5 19.6 6e-64 216.1 19.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MTHFR PF02219.17 KDO27034.1 - 3.5e-07 29.8 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4157 PF13699.6 KDO27034.1 - 0.039 14.2 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) LRR_6 PF13516.6 KDO27035.1 - 1.2e-09 37.4 0.1 0.0013 18.6 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeat Elf4 PF07011.11 KDO27035.1 - 0.057 13.3 2.5 2.4 8.1 0.3 2.7 2 0 0 2 2 2 0 Early Flowering 4 domain RNAse_A_bac PF18431.1 KDO27035.1 - 9.7 7.2 12.6 4.2 8.4 0.1 4.2 3 0 0 3 3 3 0 Bacterial CdiA-CT RNAse A domain DUF4515 PF14988.6 KDO27036.1 - 9.7e-05 22.3 2.8 0.00011 22.1 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF3557 PF12078.8 KDO27036.1 - 0.041 13.8 0.2 0.05 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) YabA PF06156.13 KDO27036.1 - 0.35 11.5 3.4 0.52 11.0 3.2 1.5 1 1 0 1 1 1 0 Initiation control protein YabA Ricin_B_lectin PF00652.22 KDO27037.1 - 2.6e-18 66.5 23.1 1.6e-11 44.6 5.7 3.5 2 1 2 4 4 4 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO27037.1 - 3.7e-10 40.4 3.5 0.023 15.4 0.0 3.8 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO27037.1 - 0.00023 20.8 5.7 0.051 13.2 1.3 3.0 1 1 0 2 2 2 2 Cytolethal distending toxin A/C domain Cornifin PF02389.15 KDO27038.1 - 0.0095 16.1 7.6 0.052 13.7 7.6 2.1 1 1 0 1 1 1 1 Cornifin (SPRR) family hNIFK_binding PF12196.8 KDO27040.1 - 0.023 14.2 2.0 4.6 6.8 1.1 2.3 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK HIT PF01230.23 KDO27042.1 - 5.6e-27 94.3 0.0 7.1e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KDO27042.1 - 2.1e-08 34.6 0.0 3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4515 PF14988.6 KDO27043.1 - 6.9e-05 22.8 31.5 6.9e-05 22.8 31.5 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) Epsilon_antitox PF08998.11 KDO27043.1 - 1.5 9.1 6.6 1.9 8.8 0.3 3.5 3 0 0 3 3 3 0 Bacterial epsilon antitoxin Nucleopor_Nup85 PF07575.13 KDO27044.1 - 2.6e-45 155.1 0.4 3.5e-45 154.6 0.4 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin NT-C2 PF10358.9 KDO27045.1 - 1.1e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ras PF00071.22 KDO27046.1 - 5.9e-36 123.5 0.0 7e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO27046.1 - 1.1e-33 116.0 0.0 1.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO27046.1 - 2.8e-08 33.4 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO27046.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO27046.1 - 0.00014 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO27046.1 - 0.0024 17.4 0.0 0.025 14.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KDO27046.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KDO27046.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain YwhD PF08741.10 KDO27046.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 YwhD family Methyltransf_11 PF08241.12 KDO27047.1 - 3.4e-14 53.2 0.0 6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27047.1 - 1.5e-12 48.0 0.0 2.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27047.1 - 1.8e-10 41.5 0.0 3.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO27047.1 - 2.9e-09 36.6 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KDO27047.1 - 2.3e-07 30.8 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO27047.1 - 0.00039 20.3 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO27047.1 - 0.01 15.4 0.1 0.03 13.9 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 KDO27047.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 KDO27047.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KDO27047.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_11 PF08241.12 KDO27048.1 - 5.7e-16 58.9 0.0 1.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27048.1 - 4.5e-15 56.1 0.0 9.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27048.1 - 1e-13 51.8 0.0 6.9e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO27048.1 - 1.5e-11 44.1 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KDO27048.1 - 2.4e-10 40.4 0.0 3.8e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO27048.1 - 2e-05 24.5 0.0 2.9e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KDO27048.1 - 0.0055 16.5 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 KDO27048.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KDO27048.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KDO27048.1 - 0.059 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 KDO27048.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KDO27048.1 - 0.082 12.5 0.1 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Anticodon_1 PF08264.13 KDO27048.1 - 0.082 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Mtc PF03820.17 KDO27049.1 - 5.2e-90 301.7 0.2 6.2e-90 301.4 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier MatE PF01554.18 KDO27051.1 - 1.6e-40 138.4 28.1 9.8e-24 83.8 10.8 2.5 2 1 0 2 2 2 2 MatE MatE PF01554.18 KDO27052.1 - 4.7e-13 49.1 7.3 5.2e-08 32.7 1.5 2.3 1 1 1 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KDO27052.1 - 0.016 15.3 1.1 0.016 15.3 1.1 1.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KDO27053.1 - 3.6e-15 56.0 8.1 4.6e-15 55.6 8.1 1.1 1 0 0 1 1 1 1 MatE PUCC PF03209.15 KDO27053.1 - 2.4e-05 23.5 5.3 3.2e-05 23.1 5.3 1.1 1 0 0 1 1 1 1 PUCC protein ECF_trnsprt PF12822.7 KDO27053.1 - 0.3 11.2 7.0 0.43 10.7 7.0 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component CxxCxxCC PF03692.15 KDO27054.1 - 8.1e-11 42.5 2.7 1.4e-10 41.7 2.7 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain HECT PF00632.25 KDO27055.1 - 2.8e-54 184.7 0.0 4.3e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KDO27055.1 - 1.4e-41 141.3 4.5 1.3e-15 57.6 0.4 3.4 3 0 0 3 3 3 3 SPRY domain MIB_HERC2 PF06701.13 KDO27055.1 - 5e-18 65.1 5.4 1.2e-17 63.9 5.4 1.7 1 0 0 1 1 1 1 Mib_herc2 UBA PF00627.31 KDO27055.1 - 5.2e-13 48.6 1.1 6.5e-06 25.9 0.0 3.0 2 0 0 2 2 2 2 UBA/TS-N domain UIM PF02809.20 KDO27055.1 - 0.018 14.9 0.6 0.11 12.5 0.6 2.5 1 0 0 1 1 1 0 Ubiquitin interaction motif MOR2-PAG1_C PF14225.6 KDO27055.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Cell morphogenesis C-terminal PRY PF13765.6 KDO27055.1 - 0.12 12.0 0.0 0.42 10.3 0.0 2.0 1 0 0 1 1 1 0 SPRY-associated domain SAGA-Tad1 PF12767.7 KDO27056.1 - 1.2e-08 35.0 0.0 1.6e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_C48 PF02902.19 KDO27060.1 - 3.5e-27 95.7 0.2 4.9e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF218 PF02698.17 KDO27062.1 - 4.4e-19 68.8 0.0 6.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain adh_short PF00106.25 KDO27063.1 - 5.5e-34 117.3 0.4 7.6e-34 116.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO27063.1 - 6.4e-30 104.4 1.7 7.8e-30 104.1 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KDO27063.1 - 6e-07 29.5 0.6 1e-06 28.8 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KDO27063.1 - 1.6e-06 28.2 0.3 2.8e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO27063.1 - 0.00013 21.6 0.1 0.00036 20.1 0.1 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KDO27063.1 - 0.0011 18.2 0.2 0.0024 17.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain ADH_zinc_N PF00107.26 KDO27063.1 - 0.018 15.0 0.2 0.033 14.2 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 KDO27063.1 - 0.034 13.7 0.4 0.072 12.6 0.1 1.7 3 0 0 3 3 3 0 NmrA-like family TrkA_N PF02254.18 KDO27063.1 - 0.055 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Bin3 PF06859.12 KDO27064.1 - 1.8e-19 70.3 0.0 2.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) dsrm PF00035.26 KDO27064.1 - 4.1e-12 46.6 0.0 6.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Methyltransf_31 PF13847.6 KDO27064.1 - 1.3e-07 31.6 0.0 0.00048 19.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27064.1 - 3.8e-06 27.5 0.1 0.016 15.9 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KDO27064.1 - 1e-05 26.1 0.0 0.042 14.5 0.0 3.4 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27064.1 - 0.0015 19.2 0.0 1.2 9.9 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KDO27064.1 - 0.0025 17.7 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain YcaO PF02624.16 KDO27064.1 - 0.041 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Glyco_hydro_18 PF00704.28 KDO27065.1 - 1.1e-07 31.9 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TACI-CRD2 PF09305.10 KDO27065.1 - 0.051 13.6 0.6 0.1 12.7 0.6 1.4 1 0 0 1 1 1 0 TACI, cysteine-rich domain Glyco_hydro_18 PF00704.28 KDO27066.1 - 7.2e-17 62.1 1.6 1.3e-16 61.3 0.3 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF4286 PF14114.6 KDO27067.1 - 2.4e-12 47.2 0.0 3.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) DUF4528 PF15031.6 KDO27067.1 - 0.14 12.2 0.1 3.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4528) FYVE PF01363.21 KDO27068.1 - 4.7e-10 39.5 19.5 1.2e-09 38.1 19.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO27068.1 - 5.8e-08 32.4 0.2 8.3e-08 31.9 0.2 1.3 1 0 0 1 1 1 1 START domain DUF5463 PF17551.2 KDO27068.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5463) DZR PF12773.7 KDO27068.1 - 1.6 8.8 15.4 2.1 8.4 3.3 2.8 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.21 KDO27069.1 - 1.4e-07 31.5 16.6 7.6e-07 29.2 16.7 2.1 1 1 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO27069.1 - 5.6e-06 25.9 0.1 9.5e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 KDO27069.1 - 0.0026 17.8 0.0 0.0048 16.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) FYVE_2 PF02318.16 KDO27069.1 - 0.0076 16.5 2.0 0.019 15.2 2.0 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.19 KDO27069.1 - 0.011 15.7 4.3 0.081 12.9 0.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_5 PF14634.6 KDO27069.1 - 0.39 10.7 13.2 0.96 9.5 13.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 KDO27069.1 - 0.92 9.6 13.5 1.2 9.2 11.5 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-CRD PF17979.1 KDO27069.1 - 1.2 9.3 9.9 2.6 8.1 9.9 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-C2H2_4 PF13894.6 KDO27069.1 - 2 9.4 10.6 12 7.0 1.1 3.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-RING_2 PF13639.6 KDO27069.1 - 3.1 8.2 13.4 21 5.5 13.6 2.4 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 KDO27069.1 - 4.6 7.2 10.6 31 4.5 10.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KDO27069.1 - 8.4 6.4 14.6 5.6 6.9 9.4 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) START PF01852.19 KDO27070.1 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 START domain zf-RING_5 PF14634.6 KDO27070.1 - 0.003 17.5 17.9 0.0085 16.0 17.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain FYVE_2 PF02318.16 KDO27070.1 - 0.01 16.0 7.1 0.021 15.0 7.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Corona_7 PF02398.16 KDO27070.1 - 0.035 14.7 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 Coronavirus protein 7 zf-RING_2 PF13639.6 KDO27070.1 - 2.7 8.4 15.8 7.7 6.9 15.8 1.8 1 0 0 1 1 1 0 Ring finger domain FYVE PF01363.21 KDO27071.1 - 3.6e-07 30.2 17.8 8.2e-07 29.1 17.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27071.1 - 0.0061 16.8 8.7 0.012 15.8 8.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-CRD PF17979.1 KDO27071.1 - 0.03 14.4 7.9 0.073 13.2 7.9 1.6 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions DUF5463 PF17551.2 KDO27071.1 - 4.3 7.3 5.5 1.8 8.5 0.7 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5463) TPMT PF05724.11 KDO27073.1 - 2.3e-17 63.4 2.7 1.3e-13 51.2 2.7 3.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KDO27073.1 - 0.00088 19.9 0.0 0.0015 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27073.1 - 0.0012 19.6 0.0 0.0019 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO27073.1 - 0.013 16.1 0.0 0.023 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KDO27075.1 - 1.4e-24 86.8 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF4286 PF14114.6 KDO27076.1 - 6e-10 39.5 0.0 7.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) DUF2807 PF10988.8 KDO27077.1 - 4.5e-06 26.6 0.8 5.1e-05 23.2 1.0 2.1 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain CreD PF06123.12 KDO27077.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD Methyltransf_11 PF08241.12 KDO27079.1 - 2.3e-15 57.0 0.0 3.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27079.1 - 5.2e-13 49.5 0.0 8.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27079.1 - 6.4e-06 26.8 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO27079.1 - 2.1e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KDO27079.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO27079.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KDO27079.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 KDO27079.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase KIX_2 PF16987.5 KDO27081.1 - 1.7e-07 31.2 0.1 5e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 KIX domain Csa1 PF06023.12 KDO27081.1 - 0.085 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Lipase_GDSL_2 PF13472.6 KDO27082.1 - 1.2e-24 87.7 0.2 1.4e-24 87.4 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO27082.1 - 7.7e-12 45.6 0.0 1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MDMPI_C PF07398.11 KDO27083.1 - 0.11 13.3 1.5 2.8 8.9 0.3 2.6 2 0 0 2 2 2 0 MDMPI C-terminal domain Tma16 PF11176.8 KDO27084.1 - 0.018 14.9 0.5 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 Translation machinery-associated protein 16 FAM184 PF15665.5 KDO27084.1 - 0.084 12.6 2.4 2.9 7.6 0.4 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B PSK_trans_fac PF07704.11 KDO27084.1 - 1 10.2 8.9 7.6 7.4 0.6 2.8 3 0 0 3 3 3 0 Rv0623-like transcription factor CBM_1 PF00734.18 KDO27085.1 - 3.2e-14 52.6 22.7 2.7e-07 30.4 8.8 2.8 2 0 0 2 2 2 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KDO27085.1 - 0.074 13.3 1.8 0.29 11.4 1.8 2.1 1 0 0 1 1 1 0 Toxin 7 Trypan_PARP PF05887.11 KDO27085.1 - 0.24 11.4 17.3 0.5 10.3 17.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBM_1 PF00734.18 KDO27086.1 - 1.7e-12 47.0 26.9 4.3e-08 33.0 9.8 3.0 2 0 0 2 2 2 2 Fungal cellulose binding domain CBM_1 PF00734.18 KDO27087.1 - 5.3e-16 58.3 22.2 2.1e-09 37.2 4.2 3.0 2 0 0 2 2 2 2 Fungal cellulose binding domain Trypan_PARP PF05887.11 KDO27087.1 - 0.0063 16.5 11.5 0.011 15.7 11.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PTN_MK_N PF05196.13 KDO27087.1 - 0.46 10.7 5.1 0.25 11.6 0.4 2.8 3 1 0 3 3 3 0 PTN/MK heparin-binding protein family, N-terminal domain Toxin_7 PF05980.12 KDO27087.1 - 8.1 6.8 7.8 0.75 10.1 2.0 2.4 2 0 0 2 2 2 0 Toxin 7 Glyco_hydro_6 PF01341.17 KDO27088.1 - 7.4e-47 160.6 3.9 1.8e-46 159.3 3.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KDO27088.1 - 1.9e-19 69.3 19.3 2.5e-09 36.9 2.8 3.1 2 0 0 2 2 2 2 Fungal cellulose binding domain PRCC PF10253.9 KDO27088.1 - 0.4 11.4 5.2 0.64 10.8 5.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KDO27088.1 - 1.1 8.4 5.0 1.4 8.0 5.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Toxin_7 PF05980.12 KDO27088.1 - 7.2 7.0 14.4 4.6 7.6 0.2 3.8 3 0 0 3 3 3 0 Toxin 7 CBM_1 PF00734.18 KDO27089.1 - 1.2e-17 63.6 19.3 1.3e-10 41.0 5.6 2.7 2 0 0 2 2 2 2 Fungal cellulose binding domain Glyco_hydro_6 PF01341.17 KDO27090.1 - 6.9e-48 163.9 5.5 1.8e-47 162.6 5.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KDO27090.1 - 3.7e-11 42.8 18.0 3.7e-11 42.8 18.0 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_6 PF01341.17 KDO27091.1 - 4.9e-49 167.7 5.0 1.1e-48 166.6 5.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KDO27091.1 - 2.1e-11 43.6 10.0 2.1e-11 43.6 10.0 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain SnoaL_2 PF12680.7 KDO27092.1 - 0.029 15.0 0.2 0.029 15.0 0.2 1.8 2 0 0 2 2 2 0 SnoaL-like domain bZIP_1 PF00170.21 KDO27092.1 - 0.034 14.3 1.8 0.059 13.5 1.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor LRR_8 PF13855.6 KDO27093.1 - 7.3e-25 86.5 19.8 5.7e-09 35.6 1.7 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KDO27093.1 - 3.5e-23 81.3 21.1 2.6e-06 27.7 0.2 5.4 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO27093.1 - 2e-09 37.2 4.7 2e-07 30.7 2.2 3.3 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KDO27093.1 - 1.7e-08 33.8 22.7 0.44 10.7 0.2 9.0 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 KDO27093.1 - 2.1e-07 30.6 7.8 2.2 9.2 0.1 8.1 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_5 PF13306.6 KDO27093.1 - 9.4e-06 25.6 0.0 0.0069 16.3 0.0 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) SAPS PF04499.15 KDO27093.1 - 2.2 6.9 7.6 3.3 6.4 7.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KDO27093.1 - 3.7 6.2 8.0 5.3 5.7 8.0 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KDO27093.1 - 8.3 4.6 11.9 11 4.2 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 KDO27095.1 - 2e-30 104.4 12.5 3.6e-05 24.4 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 KDO27095.1 - 2.9e-21 75.7 0.2 5.6e-21 74.8 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Mcl1_mid PF12341.8 KDO27095.1 - 0.0001 21.8 0.5 0.0016 17.8 0.1 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region PQQ_3 PF13570.6 KDO27095.1 - 0.00015 22.1 1.3 1.4 9.5 0.1 4.9 5 1 0 5 5 5 2 PQQ-like domain WD40 PF00400.32 KDO27096.1 - 1.6e-06 28.7 1.1 0.97 10.4 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Tetraspanin PF00335.20 KDO27097.1 - 7.4e-13 48.7 42.6 3e-09 36.9 20.1 3.0 2 2 0 2 2 2 2 Tetraspanin family Cyt_bd_oxida_II PF02322.15 KDO27097.1 - 0.0042 16.5 19.2 0.0042 16.5 19.2 2.6 2 1 1 3 3 3 1 Cytochrome bd terminal oxidase subunit II CH PF00307.31 KDO27098.1 - 2.8e-12 46.8 0.0 5.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.15 KDO27098.1 - 0.24 11.2 1.2 0.48 10.2 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3138 PF11336.8 KDO27098.1 - 0.37 9.4 1.2 0.73 8.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ELMO_CED12 PF04727.13 KDO27099.1 - 9.5e-15 55.2 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.19 KDO27099.1 - 4e-13 49.5 0.1 1.2e-12 47.9 0.1 1.9 1 0 0 1 1 1 1 RUN domain RhoGAP PF00620.27 KDO27099.1 - 1.1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain SH3_3 PF08239.11 KDO27099.1 - 0.00015 22.0 0.3 0.00043 20.5 0.3 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KDO27099.1 - 0.016 15.0 0.5 0.049 13.5 0.5 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Nuc_rec_co-act PF08815.10 KDO27099.1 - 0.061 13.2 0.4 2.8 7.9 0.0 2.8 2 0 0 2 2 2 0 Nuclear receptor coactivator PSP1 PF04468.12 KDO27100.1 - 1.7e-25 89.1 1.5 2.8e-25 88.4 1.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Alginate_lyase2 PF08787.11 KDO27102.1 - 2.1e-14 53.9 0.0 1e-11 45.1 0.0 2.1 1 1 0 1 1 1 1 Alginate lyase MFS18 PF17352.2 KDO27103.1 - 0.36 11.2 2.2 0.91 9.9 2.2 1.6 1 0 0 1 1 1 0 Male Flower Specific protein 18 Ank_2 PF12796.7 KDO27104.1 - 4.8e-29 100.8 2.3 7.2e-16 58.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO27104.1 - 1.4e-24 83.5 1.6 2e-05 24.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO27104.1 - 9.7e-23 79.6 6.8 0.00022 21.5 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KDO27104.1 - 8.9e-22 77.2 2.6 6.9e-11 42.4 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27104.1 - 7.2e-19 67.6 5.6 9.1e-05 22.7 0.1 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) U-box PF04564.15 KDO27104.1 - 1.3e-15 57.4 0.0 2.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO27104.1 - 2.3e-05 24.1 0.0 6.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Acyl-CoA_dh_1 PF00441.24 KDO27105.1 - 4.8e-44 150.2 5.0 6e-42 143.4 0.3 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KDO27105.1 - 1.7e-25 89.1 0.0 3.3e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KDO27105.1 - 1.9e-22 80.0 0.0 7.6e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KDO27105.1 - 2.7e-14 53.6 1.1 1.7e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KDO27105.1 - 0.18 11.5 0.9 1.5 8.4 0.4 2.6 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF5590 PF17881.1 KDO27106.1 - 0.56 10.3 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) EMP70 PF02990.16 KDO27107.1 - 0.025 13.3 3.5 0.03 13.0 3.5 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 Na_K-ATPase PF00287.18 KDO27107.1 - 0.18 10.9 1.4 0.17 11.1 0.5 1.3 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain ABC2_membrane_2 PF12679.7 KDO27107.1 - 0.21 10.8 4.9 0.26 10.5 4.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4191 PF13829.6 KDO27107.1 - 0.85 8.9 2.3 1 8.7 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF485 PF04341.12 KDO27107.1 - 5.3 7.1 9.5 8.2 6.5 9.4 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF485 Homeodomain PF00046.29 KDO27110.1 - 6e-24 83.7 7.2 6.3e-09 35.5 0.2 4.6 4 0 0 4 4 4 3 Homeodomain PHD PF00628.29 KDO27110.1 - 4.4e-07 29.7 8.8 7.8e-07 28.9 8.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-4CXXC_R1 PF10497.9 KDO27110.1 - 0.00035 20.7 7.2 0.00079 19.6 7.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Homeobox_KN PF05920.11 KDO27110.1 - 0.0062 16.4 2.5 0.91 9.5 0.2 3.6 3 0 0 3 3 3 1 Homeobox KN domain zf-RING_2 PF13639.6 KDO27110.1 - 0.012 16.0 9.7 0.02 15.2 9.7 1.4 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 KDO27110.1 - 0.018 14.6 3.2 0.043 13.4 3.2 1.6 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KDO27110.1 - 0.026 14.6 7.1 0.087 12.9 7.1 1.9 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KDO27110.1 - 0.027 14.8 1.1 0.058 13.7 1.1 1.5 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 KDO27110.1 - 0.039 14.1 7.2 0.11 12.6 7.2 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 KDO27110.1 - 0.043 14.1 7.3 0.12 12.6 7.3 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain Membrane_bind PF14564.6 KDO27110.1 - 0.05 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Membrane binding DUF2318 PF10080.9 KDO27110.1 - 0.098 12.8 1.7 0.27 11.4 1.7 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) HTH_48 PF17906.1 KDO27110.1 - 0.099 12.8 0.6 14 5.9 0.1 3.2 3 0 0 3 3 3 0 HTH domain in Mos1 transposase C1_1 PF00130.22 KDO27110.1 - 0.12 12.3 10.1 0.025 14.5 6.7 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KDO27110.1 - 0.3 11.0 8.0 0.63 10.0 8.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 KDO27110.1 - 0.33 10.9 12.6 0.19 11.7 9.0 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Cytochrome_C7 PF14522.6 KDO27110.1 - 0.9 9.6 7.9 3.3 7.8 7.9 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 KDO27110.1 - 2.7 8.4 10.9 1 9.7 7.8 1.9 2 0 0 2 2 1 0 Class III cytochrome C family zf-RING-like PF08746.11 KDO27110.1 - 9.5 6.6 10.7 17 5.9 10.7 1.4 1 0 0 1 1 1 0 RING-like domain TPR_14 PF13428.6 KDO27111.1 - 5.8e-06 26.7 2.5 0.087 13.7 0.1 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27111.1 - 7.9e-06 26.3 0.1 1.8e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO27111.1 - 0.016 15.2 0.0 0.077 13.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27111.1 - 0.029 14.6 2.8 0.031 14.6 0.8 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27111.1 - 0.17 12.1 6.8 0.18 12.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO27111.1 - 0.21 12.3 0.5 6.4 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO27111.1 - 0.43 11.3 0.1 0.43 11.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO27111.1 - 1.6 9.5 6.9 0.13 13.0 1.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MatE PF01554.18 KDO27112.1 - 1.4e-28 99.5 19.2 6.5e-24 84.4 6.1 2.3 2 0 0 2 2 2 2 MatE Glyco_hydro_6 PF01341.17 KDO27113.1 - 2e-43 149.3 7.1 4.7e-43 148.1 7.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 PAN_4 PF14295.6 KDO27113.1 - 8e-20 70.5 29.5 2.1e-06 27.5 6.1 3.9 3 0 0 3 3 3 3 PAN domain DUF1611 PF07755.11 KDO27113.1 - 0.052 12.8 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain ELFV_dehydrog_N PF02812.18 KDO27113.1 - 0.09 12.7 0.5 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Whib PF02467.16 KDO27113.1 - 1.8 9.2 12.0 33 5.2 0.5 3.7 3 0 0 3 3 3 0 Transcription factor WhiB CBM_1 PF00734.18 KDO27114.1 - 2.5e-11 43.3 8.4 2.5e-11 43.3 8.4 2.7 2 1 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO27114.1 - 0.00072 19.0 20.5 0.00072 19.0 20.5 3.9 4 1 1 5 5 5 1 PT repeat FAP PF07174.11 KDO27114.1 - 0.078 12.4 15.8 0.17 11.3 15.8 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PRCC PF10253.9 KDO27114.1 - 4.9 7.9 10.7 7.8 7.2 10.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PT PF04886.12 KDO27115.1 - 5.9e-15 54.5 44.0 1.4e-09 37.3 20.2 5.1 3 1 2 5 5 5 3 PT repeat Glyco_hydro_6 PF01341.17 KDO27116.1 - 3.7e-47 161.6 0.9 7.1e-47 160.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PAN_4 PF14295.6 KDO27116.1 - 9.7e-15 54.2 24.2 5.5e-06 26.2 2.9 3.9 3 0 0 3 3 3 3 PAN domain START PF01852.19 KDO27117.1 - 5e-07 29.3 0.0 8.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO27117.1 - 0.041 14.0 16.7 0.1 12.7 16.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger ATXN-1_C PF12547.8 KDO27119.1 - 1.1 9.6 5.9 31 5.0 5.2 2.5 1 1 1 2 2 2 0 Capicua transcriptional repressor modulator ATXN-1_C PF12547.8 KDO27120.1 - 4.2 7.8 8.3 23 5.4 4.7 2.5 1 1 1 2 2 2 0 Capicua transcriptional repressor modulator GDPD PF03009.17 KDO27121.1 - 1.9e-18 67.1 0.0 2.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 KDO27122.1 - 1.3e-18 67.7 0.0 1.8e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Rbsn PF11464.8 KDO27123.1 - 0.037 13.8 0.6 0.12 12.1 0.6 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Asp-B-Hydro_N PF05279.11 KDO27123.1 - 0.041 13.9 0.3 0.059 13.4 0.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FliT PF05400.13 KDO27123.1 - 3.1 8.7 11.9 3.4 8.5 3.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliT GCP_C_terminal PF04130.13 KDO27124.1 - 2.4e-83 280.1 13.5 3.5e-83 279.6 12.4 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KDO27124.1 - 9.3e-56 189.7 0.1 3.1e-54 184.7 0.1 2.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Cytochrom_C1 PF02167.15 KDO27125.1 - 0.048 13.4 0.5 0.081 12.6 0.4 1.5 1 1 0 1 1 1 0 Cytochrome C1 family HrcA PF01628.21 KDO27125.1 - 0.08 12.8 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 HrcA protein C terminal domain TLD PF07534.16 KDO27126.1 - 2.6e-29 102.2 0.0 4.4e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 TLD PDZ_6 PF17820.1 KDO27126.1 - 4.8e-11 42.3 0.0 1.7e-06 27.8 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KDO27126.1 - 1.7e-07 31.5 0.0 0.025 14.9 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO27126.1 - 0.02 15.2 0.0 1.4 9.3 0.0 2.6 3 0 0 3 3 3 0 PDZ domain Pkinase PF00069.25 KDO27127.1 - 3.8e-48 164.2 0.0 4.7e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27127.1 - 4.9e-25 88.3 0.0 5.5e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27127.1 - 8e-05 22.1 0.0 0.00015 21.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO27127.1 - 0.00079 18.8 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO27127.1 - 0.03 13.3 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO27127.1 - 0.039 13.9 3.4 0.74 9.7 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO27128.1 - 1.1e-44 152.8 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27128.1 - 2.6e-29 102.3 0.0 3e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO27128.1 - 1.6e-05 24.3 0.6 2.4e-05 23.8 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO27128.1 - 2.6e-05 24.3 1.9 0.031 14.2 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO27128.1 - 5.3e-05 22.7 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO27128.1 - 0.0029 17.3 0.0 0.006 16.2 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KDO27128.1 - 0.019 13.9 0.1 0.024 13.6 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KDO27128.1 - 0.044 13.4 0.1 0.073 12.7 0.1 1.3 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KDO27129.1 - 9.3e-45 153.0 0.0 1e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27129.1 - 2.7e-30 105.5 0.0 3.2e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO27129.1 - 1.2e-05 25.4 1.8 0.013 15.4 0.2 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO27129.1 - 0.00018 20.9 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO27129.1 - 0.00026 20.4 0.4 0.00037 19.9 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO27129.1 - 0.0066 16.1 0.1 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KDO27129.1 - 0.0085 15.1 0.1 0.01 14.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 KDO27130.1 - 5.4e-36 124.3 0.0 1.1e-35 123.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27130.1 - 3.3e-22 79.0 0.0 6.3e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO27130.1 - 0.00011 22.2 0.4 0.00016 21.7 0.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO27130.1 - 0.016 14.6 0.8 0.023 14.1 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_3 PF13456.6 KDO27131.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Pkinase PF00069.25 KDO27132.1 - 4.5e-48 163.9 0.0 2.5e-47 161.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27132.1 - 1.8e-27 96.3 0.1 2.7e-26 92.4 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO27132.1 - 1.7e-06 27.3 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO27132.1 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO27132.1 - 0.0013 18.1 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO27132.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Adaptin_N PF01602.20 KDO27132.1 - 0.085 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region APH PF01636.23 KDO27132.1 - 0.42 10.5 3.3 0.21 11.5 0.3 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO27133.1 - 2.2e-50 171.5 0.0 2.8e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27133.1 - 4.3e-27 95.0 0.0 6.2e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27133.1 - 1.5e-06 27.8 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO27133.1 - 4.3e-05 22.5 0.0 6.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO27133.1 - 0.00047 19.2 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO27133.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO27133.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO27134.1 - 1.7e-45 155.5 0.0 2.1e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27134.1 - 2.9e-28 98.9 0.0 3.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27134.1 - 0.0021 17.5 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO27134.1 - 0.011 15.1 0.3 0.018 14.4 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO27134.1 - 0.036 13.0 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KDO27135.1 - 3.2e-48 164.4 0.0 3.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27135.1 - 4.2e-29 101.6 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27135.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO27135.1 - 0.005 16.2 0.2 0.0069 15.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO27135.1 - 0.022 13.7 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO27135.1 - 0.11 12.3 0.9 0.53 10.2 0.9 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.25 KDO27136.1 - 8e-53 179.6 0.0 4.3e-52 177.2 0.0 1.9 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO27136.1 - 4.7e-25 88.2 0.0 7.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KDO27136.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Misat_Tub_SegII PF10644.9 KDO27136.1 - 0.022 15.1 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain UCR_TM PF02921.14 KDO27137.1 - 2.5e-15 56.7 0.5 4.8e-15 55.8 0.5 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KDO27137.1 - 4.8e-12 45.7 0.1 9.7e-12 44.7 0.1 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain FeoB_C PF07664.12 KDO27137.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF4752 PF15944.5 KDO27137.1 - 0.088 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) Ribosomal_S13_N PF08069.12 KDO27138.1 - 1.3e-31 108.4 0.3 2.5e-31 107.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KDO27138.1 - 5.3e-14 52.2 1.2 7.3e-14 51.7 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Fungal_trans_2 PF11951.8 KDO27138.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Asp_Arg_Hydrox PF05118.15 KDO27139.1 - 2.1e-48 164.1 0.1 2.5e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF4286 PF14114.6 KDO27140.1 - 0.12 12.9 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Pkinase_Tyr PF07714.17 KDO27143.1 - 9.9e-47 159.4 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO27143.1 - 4.6e-45 154.0 0.0 6.4e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO27143.1 - 0.021 13.8 0.0 0.043 12.8 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain CD34_antigen PF06365.12 KDO27143.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family VanZ PF04892.12 KDO27144.1 - 6.5e-09 36.5 0.1 7.5e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 VanZ like family DUF2809 PF10990.8 KDO27144.1 - 0.22 12.2 2.0 0.74 10.5 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2809) DnaJ_C PF01556.18 KDO27145.1 - 6.4e-41 139.9 0.7 8.7e-41 139.5 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO27145.1 - 1e-21 76.8 0.1 2.1e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KDO27145.1 - 1.9e-14 53.7 18.5 3.6e-14 52.9 18.5 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KDO27145.1 - 0.055 13.5 6.0 1.7 8.7 1.3 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KDO27145.1 - 4.5 7.5 8.1 0.62 10.2 0.9 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 Pkinase_Tyr PF07714.17 KDO27148.1 - 2.1e-52 178.0 0.0 2.6e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO27148.1 - 4.6e-52 177.0 0.0 6.4e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO27148.1 - 0.002 17.1 0.3 0.0063 15.5 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain MASE1 PF05231.14 KDO27148.1 - 0.0055 15.9 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 MASE1 Kdo PF06293.14 KDO27148.1 - 0.051 12.9 0.1 0.097 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 KDO27148.1 - 0.12 13.3 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 KDO27148.1 - 0.48 10.6 3.7 1.1 9.4 3.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pkinase PF00069.25 KDO27149.1 - 6.5e-52 176.5 0.0 8.4e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27149.1 - 5.1e-50 170.2 0.0 6.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO27149.1 - 0.033 13.2 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SARAF PF06682.12 KDO27149.1 - 0.23 11.1 0.0 0.33 10.6 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SKG6 PF08693.10 KDO27149.1 - 0.23 10.9 2.9 0.43 10.0 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DnaJ_C PF01556.18 KDO27150.1 - 1.6e-40 138.6 0.6 2.1e-40 138.2 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO27150.1 - 3.3e-22 78.4 0.2 6.3e-22 77.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KDO27150.1 - 3.7e-15 56.0 19.0 7e-15 55.1 19.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KDO27150.1 - 0.031 14.3 6.0 2.2 8.3 1.2 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KDO27150.1 - 3.4 7.9 5.7 0.66 10.2 0.9 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 RNA_pol_Rpb2_6 PF00562.28 KDO27151.1 - 2.1e-124 415.5 0.0 3.2e-124 414.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KDO27151.1 - 2.4e-67 226.4 0.1 3.3e-67 225.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KDO27151.1 - 4.1e-52 176.6 0.0 8.2e-52 175.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KDO27151.1 - 7.1e-33 112.9 0.1 2.1e-32 111.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KDO27151.1 - 2.9e-26 91.4 0.0 6.3e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KDO27151.1 - 3.6e-25 88.0 1.4 6.5e-25 87.2 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KDO27151.1 - 1.9e-15 57.2 2.5 5.7e-15 55.6 2.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF1361 PF07099.11 KDO27153.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) LRR_4 PF12799.7 KDO27153.1 - 0.17 12.4 0.1 2.7 8.5 0.0 3.0 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) DUF2275 PF10039.9 KDO27154.1 - 0.33 11.0 1.2 0.68 10.0 0.0 2.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2275) DnaJ PF00226.31 KDO27156.1 - 3.3e-19 68.8 0.1 5.9e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain E1-E2_ATPase PF00122.20 KDO27157.1 - 1.7e-53 180.9 0.6 1.7e-53 180.9 0.6 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KDO27157.1 - 1.5e-46 158.4 0.2 1.5e-46 158.4 0.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KDO27157.1 - 1.4e-22 81.1 7.3 1.8e-21 77.4 7.3 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO27157.1 - 1.8e-17 62.8 0.0 4e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KDO27157.1 - 4.7e-15 55.4 0.0 1.1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KDO27157.1 - 0.0002 21.2 1.8 0.00035 20.4 1.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Thaumatin PF00314.17 KDO27159.1 - 5.7e-05 22.8 2.2 0.03 14.0 0.3 2.3 1 1 1 2 2 2 2 Thaumatin family SWIM PF04434.17 KDO27161.1 - 0.017 14.8 4.1 0.066 12.9 4.1 1.9 1 1 0 1 1 1 0 SWIM zinc finger TTRAP PF14203.6 KDO27161.1 - 0.046 13.7 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein UCH PF00443.29 KDO27162.1 - 4.3e-41 141.1 0.0 3.6e-40 138.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KDO27162.1 - 1.9e-33 115.8 0.0 6.1e-19 68.3 0.0 2.4 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 KDO27162.1 - 9.3e-17 61.6 0.0 1.6e-07 31.3 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KDO27162.1 - 1.1e-16 61.1 0.0 5.3e-16 59.0 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal LicD PF04991.13 KDO27163.1 - 1.1e-19 71.4 0.0 1.1e-18 68.3 0.0 2.1 1 1 0 1 1 1 1 LicD family GRA6 PF05084.13 KDO27164.1 - 1 9.3 2.9 1.8 8.5 2.9 1.4 1 1 0 1 1 1 0 Granule antigen protein (GRA6) LicD PF04991.13 KDO27165.1 - 3.7e-20 73.1 0.0 2.7e-19 70.2 0.0 2.1 1 1 0 1 1 1 1 LicD family DHO_dh PF01180.21 KDO27166.1 - 2e-52 178.2 0.0 2.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KDO27166.1 - 7.9e-05 22.2 0.2 0.00012 21.5 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KDO27166.1 - 0.00019 20.6 0.1 0.00031 19.9 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KDO27166.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.17 KDO27166.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 KDO27166.1 - 0.043 12.9 0.1 5.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF4805 PF16063.5 KDO27166.1 - 0.19 11.0 1.5 0.37 10.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) DUF3262 PF11660.8 KDO27166.1 - 0.21 12.0 0.3 0.67 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) 2OG-FeII_Oxy_3 PF13640.6 KDO27167.1 - 2.7e-06 28.2 0.0 0.0024 18.7 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 KDO27168.1 - 1.1e-14 55.5 3.6 1.6e-14 54.9 3.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO27168.1 - 9.8e-07 29.5 0.6 3e-06 28.0 0.2 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KDO27168.1 - 5.7e-06 26.8 0.1 3.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 KDO27168.1 - 0.00046 20.4 0.5 0.21 11.7 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KDO27169.1 - 3e-16 60.5 1.8 4.8e-16 59.9 1.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KDO27169.1 - 2.1e-06 28.2 0.1 2.1e-06 28.2 0.1 2.7 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KDO27169.1 - 3.2e-06 27.9 0.7 3e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 KDO27169.1 - 0.0048 17.1 0.0 0.16 12.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BT1 PF03092.16 KDO27170.1 - 5.4e-08 31.5 16.3 5.7e-08 31.4 2.4 3.2 3 0 0 3 3 3 3 BT1 family S4 PF01479.25 KDO27171.1 - 1.6e-10 40.6 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KDO27171.1 - 6.9e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 S4 domain EF-hand_1 PF00036.32 KDO27172.1 - 1.4e-25 86.9 12.7 4.6e-06 25.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO27172.1 - 4.3e-24 84.8 6.6 6.2e-13 49.0 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO27172.1 - 4.7e-22 76.0 7.3 1.1e-06 28.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO27172.1 - 2.9e-17 61.3 9.2 0.00023 20.5 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KDO27172.1 - 4.5e-16 58.4 10.4 1.1e-07 31.6 0.5 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO27172.1 - 1.7e-07 31.6 0.2 0.025 14.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO27172.1 - 8.8e-07 29.2 0.1 0.13 12.6 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 KDO27172.1 - 1.3e-06 28.3 1.2 0.29 11.1 0.0 3.2 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand RNA_pol_Rpc4 PF05132.14 KDO27173.1 - 5.2e-21 75.6 0.2 4.9e-18 66.0 0.2 2.3 1 1 0 1 1 1 1 RNA polymerase III RPC4 FlpD PF02662.16 KDO27174.1 - 0.039 14.0 0.0 0.045 13.8 0.0 1.0 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Ras PF00071.22 KDO27174.1 - 0.091 12.3 0.0 0.88 9.1 0.1 1.9 1 1 1 2 2 2 0 Ras family Dzip-like_N PF13815.6 KDO27175.1 - 2.3e-06 27.6 0.6 2.3e-06 27.6 0.6 2.7 2 1 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 KDO27175.1 - 0.011 16.5 0.9 0.039 14.8 0.9 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KDO27175.1 - 0.012 16.0 2.0 0.019 15.4 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Phage_GP20 PF06810.11 KDO27175.1 - 0.019 14.8 1.9 0.31 10.8 0.7 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 zf-C2H2_6 PF13912.6 KDO27175.1 - 0.022 14.8 0.5 0.041 13.9 0.5 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Strep_SA_rep PF06696.11 KDO27175.1 - 0.023 14.7 4.4 1.8 8.7 0.0 3.4 3 0 0 3 3 3 0 Streptococcal surface antigen repeat DUF2156 PF09924.9 KDO27175.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) ARS2 PF04959.13 KDO27175.1 - 0.57 10.5 1.4 1 9.7 0.0 2.0 2 1 0 2 2 2 0 Arsenite-resistance protein 2 Cnn_1N PF07989.11 KDO27175.1 - 4.8 7.4 7.0 1.4 9.1 1.0 2.7 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 LRRFIP PF09738.9 KDO27175.1 - 9 5.7 12.5 0.59 9.6 4.1 2.5 2 1 0 3 3 3 0 LRRFIP family RNase_Zc3h12a PF11977.8 KDO27176.1 - 6.5e-17 61.7 0.1 6.5e-17 61.7 0.1 2.9 2 1 1 3 3 3 1 Zc3h12a-like Ribonuclease NYN domain KH_1 PF00013.29 KDO27176.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 KH domain EIF4E-T PF10477.9 KDO27176.1 - 0.44 9.3 23.0 0.54 9.0 23.0 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4411 PF14367.6 KDO27176.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Hydin_ADK PF17213.3 KDO27176.1 - 3 8.1 13.9 0.87 9.8 10.8 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Caldesmon PF02029.15 KDO27176.1 - 6.4 5.4 16.4 9.4 4.9 16.4 1.2 1 0 0 1 1 1 0 Caldesmon Activator_LAG-3 PF11498.8 KDO27176.1 - 6.8 5.6 65.5 12 4.7 65.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PDEase_I PF00233.19 KDO27178.1 - 6.9e-55 186.4 0.0 1.4e-54 185.4 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ank_4 PF13637.6 KDO27178.1 - 1.5e-30 105.2 0.3 8.2e-11 42.2 0.0 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO27178.1 - 6e-30 103.7 0.5 2.4e-13 50.4 0.5 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO27178.1 - 5.9e-19 67.6 1.1 0.00016 22.0 0.1 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO27178.1 - 1.1e-18 67.1 1.2 1.9e-06 28.0 0.0 6.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27178.1 - 3.7e-18 63.7 0.9 0.0046 17.4 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Aldo_ket_red PF00248.21 KDO27179.1 - 1.6e-05 24.3 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family GAF PF01590.26 KDO27180.1 - 2.7e-19 70.1 0.9 1.2e-09 38.8 0.1 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KDO27180.1 - 6.4e-11 42.7 0.0 7.9e-06 26.2 0.0 2.8 3 0 0 3 3 3 2 GAF domain PDEase_I PF00233.19 KDO27181.1 - 1.1e-62 211.9 8.2 2.2e-62 210.9 8.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KDO27181.1 - 3.1e-46 157.3 3.9 2e-14 54.4 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 KDO27181.1 - 3.4e-44 150.5 0.5 9.4e-11 42.2 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 KDO27181.1 - 1.1e-23 84.0 0.2 5.1e-06 26.9 0.0 4.8 5 0 0 5 5 5 4 GAF domain SpoVT_C PF15714.5 KDO27181.1 - 0.0058 16.7 0.0 6 6.9 0.0 3.4 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor zf-met PF12874.7 KDO27182.1 - 2.9e-08 33.8 0.2 4.8e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KDO27182.1 - 4.3e-06 26.9 0.0 7.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 KDO27182.1 - 1.9e-05 24.7 3.2 1.9e-05 24.7 3.2 2.2 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins SURF2 PF05477.11 KDO27182.1 - 0.00065 19.5 2.2 0.00091 19.0 2.2 1.3 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) zf-U1 PF06220.12 KDO27182.1 - 0.0091 15.7 0.2 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-DBF PF07535.12 KDO27182.1 - 0.042 14.0 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger SBDS_C PF09377.10 KDO27183.1 - 6.6e-33 113.2 1.0 1.4e-32 112.2 1.0 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KDO27183.1 - 2.4e-28 98.0 0.8 4.2e-28 97.3 0.8 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein L27_1 PF09058.10 KDO27183.1 - 0.13 12.2 0.3 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 L27_1 Enkurin PF13864.6 KDO27184.1 - 8.3e-25 87.1 1.1 8.3e-25 87.1 1.1 2.8 2 1 0 2 2 2 1 Calmodulin-binding Nop14 PF04147.12 KDO27185.1 - 1.1e-187 626.1 56.7 2e-187 625.3 56.7 1.3 1 1 0 1 1 1 1 Nop14-like family CCDC53 PF10152.9 KDO27186.1 - 1.7 9.1 3.7 1.8 9.0 1.9 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 KDO27186.1 - 4 8.1 14.4 1.3 9.7 10.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GSHPx PF00255.19 KDO27187.1 - 6.3e-26 90.1 0.0 8.6e-26 89.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KDO27187.1 - 0.027 14.4 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family Cation_efflux PF01545.21 KDO27188.1 - 6.3e-44 150.1 2.1 5.1e-43 147.1 2.1 2.0 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KDO27188.1 - 9.7e-22 76.9 6.5 2.9e-14 53.0 0.6 3.4 3 0 0 3 3 3 2 Dimerisation domain of Zinc Transporter PEX11 PF05648.14 KDO27189.1 - 1.5e-21 76.9 0.1 2.1e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DAGK_cat PF00781.24 KDO27190.1 - 4.9e-22 77.9 0.0 8.7e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 KDO27190.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hist_deacetyl PF00850.19 KDO27191.1 - 2.9e-58 197.8 0.0 6.4e-58 196.6 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain DUF3828 PF12883.7 KDO27191.1 - 0.019 15.3 0.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) DeoC PF01791.9 KDO27191.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DeoC/LacD family aldolase PH PF00169.29 KDO27192.1 - 3.3e-09 37.2 0.4 6.7e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO27192.1 - 0.02 15.1 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Com_YlbF PF06133.11 KDO27192.1 - 0.16 12.6 1.8 0.29 11.8 1.8 1.3 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA zf-RING_2 PF13639.6 KDO27193.1 - 3.5e-12 46.4 8.9 3.5e-12 46.4 8.9 4.5 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO27193.1 - 1.9e-09 37.2 6.8 1.9e-09 37.2 6.8 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO27193.1 - 7.3e-09 35.4 5.0 7.3e-09 35.4 5.0 5.0 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO27193.1 - 4.7e-08 33.2 6.1 4.7e-08 33.2 6.1 3.7 4 0 0 4 4 4 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KDO27193.1 - 1.6e-07 31.0 6.0 1.6e-07 31.0 6.0 4.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO27193.1 - 2.8e-07 30.3 6.0 2.8e-07 30.3 6.0 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO27193.1 - 9.4e-06 25.6 5.1 4.6e-05 23.4 5.1 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO27193.1 - 4.4e-05 23.1 5.2 4.4e-05 23.1 5.2 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO27193.1 - 0.00052 19.9 6.8 0.00052 19.9 6.8 4.2 3 2 0 3 3 3 1 zinc-RING finger domain Frag1 PF10277.9 KDO27194.1 - 9e-14 51.5 22.4 1.2e-13 51.1 22.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Peptidase_C78 PF07910.13 KDO27195.1 - 3.3e-26 92.1 0.0 5e-25 88.2 0.0 2.0 2 0 0 2 2 2 2 Peptidase family C78 Myb_DNA-binding PF00249.31 KDO27196.1 - 1e-16 60.9 0.1 3.5e-08 33.5 0.0 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO27196.1 - 3.9e-05 23.8 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain LMP PF04778.12 KDO27196.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 LMP repeated region HEAT_EZ PF13513.6 KDO27197.1 - 2e-29 101.6 12.9 1.8e-12 47.5 0.0 9.7 10 2 2 12 12 11 3 HEAT-like repeat HEAT PF02985.22 KDO27197.1 - 1.5e-27 93.2 8.7 0.00096 19.2 0.0 11.3 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 KDO27197.1 - 8.3e-19 67.8 0.0 0.18 12.2 0.0 7.5 5 3 2 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO27197.1 - 4.7e-13 49.5 0.0 0.0019 18.8 0.1 5.7 4 1 1 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO27197.1 - 1.4e-11 44.7 0.2 0.006 16.6 0.0 4.4 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KDO27197.1 - 9.1e-11 41.0 1.3 0.0027 16.3 0.0 4.0 3 1 1 4 4 4 3 Adaptin N terminal region MMS19_C PF12460.8 KDO27197.1 - 1.3e-08 34.4 3.0 0.00016 20.9 0.0 4.3 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KDO27197.1 - 1.6e-08 34.4 0.1 1.2e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 KDO27197.1 - 9e-07 28.7 1.4 8 6.7 0.0 6.7 7 1 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 KDO27197.1 - 8.5e-05 22.4 1.0 2.9 7.6 0.4 4.1 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KDO27197.1 - 0.00051 19.7 0.0 1.3 8.5 0.0 4.3 4 1 1 5 5 5 1 CLASP N terminal ANAPC15 PF15243.6 KDO27197.1 - 0.025 14.9 4.5 0.066 13.6 4.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TAF6_C PF07571.13 KDO27197.1 - 0.027 14.8 0.1 12 6.3 0.0 3.7 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain DUF3437 PF11919.8 KDO27197.1 - 0.042 13.8 0.0 5.4 7.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Cnd3 PF12719.7 KDO27197.1 - 0.051 12.8 0.8 5.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Tti2 PF10521.9 KDO27197.1 - 0.29 10.7 5.1 2 7.9 0.0 4.4 6 0 0 6 6 6 0 Tti2 family DNA_pol_phi PF04931.13 KDO27197.1 - 1.2 7.1 5.4 2.4 6.2 5.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 KDO27197.1 - 2.1 8.7 6.6 4 7.9 6.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYVE PF01363.21 KDO27199.1 - 1e-18 67.2 5.4 1.8e-18 66.5 5.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH_6 PF15406.6 KDO27199.1 - 0.00035 20.8 0.0 0.00067 19.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.16 KDO27199.1 - 0.037 14.2 8.9 0.046 13.9 2.1 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger PH_13 PF16652.5 KDO27199.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain Zn-ribbon_8 PF09723.10 KDO27199.1 - 0.12 12.5 7.8 1.8 8.8 3.7 2.7 1 1 1 2 2 2 0 Zinc ribbon domain Band_7 PF01145.25 KDO27200.1 - 8.8e-37 126.8 4.0 2.7e-36 125.2 4.0 1.8 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KDO27200.1 - 0.0026 17.5 0.1 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family DUF599 PF04654.12 KDO27200.1 - 0.014 14.8 0.4 0.024 14.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Flot PF15975.5 KDO27200.1 - 0.48 10.6 5.3 0.65 10.2 2.1 2.2 1 1 1 2 2 2 0 Flotillin Na_Pi_cotrans PF02690.15 KDO27201.1 - 0.22 11.6 5.7 0.68 10.0 5.7 1.8 1 0 0 1 1 1 0 Na+/Pi-cotransporter Pkinase PF00069.25 KDO27202.1 - 8.3e-51 172.9 0.0 2e-50 171.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27202.1 - 2.2e-24 86.2 0.0 3.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27202.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO27202.1 - 0.0042 17.0 0.0 0.031 14.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Transformer PF06495.11 KDO27202.1 - 0.84 9.7 30.0 1.7 8.7 30.0 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein V-SNARE_C PF12352.8 KDO27203.1 - 3.5e-17 62.4 1.3 9.9e-17 61.0 1.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KDO27203.1 - 2.1e-08 34.0 0.4 8.9e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Sec20 DUF3450 PF11932.8 KDO27203.1 - 0.02 14.2 3.2 1.1 8.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Complex1_LYR PF05347.15 KDO27204.1 - 2e-06 27.7 1.2 3.2e-06 27.1 1.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) NYD-SP28_assoc PF14775.6 KDO27205.1 - 0.0027 17.8 1.3 0.67 10.1 0.1 3.0 2 0 0 2 2 2 2 Sperm tail C-terminal domain BBS2_C PF14782.6 KDO27205.1 - 0.21 10.3 3.6 0.27 10.0 3.0 1.4 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal COG5 PF10392.9 KDO27205.1 - 0.32 11.2 6.2 0.1 12.8 2.2 2.3 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Jnk-SapK_ap_N PF09744.9 KDO27205.1 - 0.5 10.6 19.7 0.21 11.8 8.7 3.1 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 KDO27205.1 - 1.2 9.3 12.7 11 6.2 0.1 4.0 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 FlxA PF14282.6 KDO27205.1 - 2.9 8.0 11.4 1.7 8.7 7.5 2.7 1 1 1 2 2 2 0 FlxA-like protein LRR_6 PF13516.6 KDO27206.1 - 1e-12 47.0 24.0 0.032 14.3 1.5 8.8 9 0 0 9 9 9 4 Leucine Rich repeat IQ PF00612.27 KDO27206.1 - 4.7e-10 38.4 99.2 0.011 15.5 0.3 13.2 12 1 1 13 13 13 7 IQ calmodulin-binding motif LRR_4 PF12799.7 KDO27206.1 - 9.8e-08 32.2 0.1 0.45 11.0 0.1 5.1 2 2 3 7 7 7 3 Leucine Rich repeats (2 copies) WW PF00397.26 KDO27206.1 - 2.3e-06 27.6 19.1 5.5e-05 23.2 3.8 3.6 4 0 0 4 4 4 2 WW domain zf-B_box PF00643.24 KDO27206.1 - 5.9e-05 23.1 3.5 0.0002 21.4 3.5 1.9 1 0 0 1 1 1 1 B-box zinc finger LRR_8 PF13855.6 KDO27206.1 - 0.0065 16.2 0.8 2.7 7.8 0.2 4.3 5 2 1 6 6 6 1 Leucine rich repeat IBR PF01485.21 KDO27206.1 - 0.029 14.6 2.6 0.094 13.0 2.6 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain LRR_1 PF00560.33 KDO27206.1 - 0.051 14.1 6.8 1.6e+02 3.5 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat CEBP_ZZ PF16366.5 KDO27206.1 - 0.53 10.6 9.8 0.032 14.5 3.8 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1298 PF06974.13 KDO27208.1 - 8.3e-11 42.0 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KDO27208.1 - 3.2e-06 27.1 0.0 1.5e-05 24.9 0.0 2.0 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Pro_isomerase PF00160.21 KDO27209.1 - 3.3e-32 111.9 0.0 3.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GBP PF02263.19 KDO27210.1 - 3.8e-64 216.5 0.0 7.3e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KDO27210.1 - 3.2e-21 76.0 7.3 8.6e-15 54.9 0.3 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, C-terminal domain PH PF00169.29 KDO27210.1 - 2.2e-09 37.8 0.0 4.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 KDO27210.1 - 0.043 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PH_11 PF15413.6 KDO27210.1 - 0.044 14.2 0.3 0.36 11.3 0.3 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 KDO27210.1 - 0.14 12.4 0.1 0.96 9.8 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain TolA_bind_tri PF16331.5 KDO27210.1 - 0.18 11.9 1.6 8.3 6.6 0.2 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation IFN-gamma PF00714.17 KDO27210.1 - 0.2 11.5 1.3 0.46 10.3 0.1 2.1 2 0 0 2 2 2 0 Interferon gamma Mt_ATP-synt_D PF05873.12 KDO27210.1 - 0.25 11.2 2.6 7.5 6.4 0.2 2.6 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DNA_pol_E_B PF04042.16 KDO27212.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Metallophos_3 PF14582.6 KDO27212.1 - 0.025 13.9 0.0 0.99 8.7 0.1 2.5 2 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Pkinase PF00069.25 KDO27213.1 - 3.4e-52 177.4 0.0 4.1e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27213.1 - 3.4e-26 92.1 0.0 1.3e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27213.1 - 1.3e-06 27.9 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO27213.1 - 0.00023 21.2 0.2 0.00045 20.2 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO27213.1 - 0.0082 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO27213.1 - 0.024 14.0 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FA_FANCE PF11510.8 KDO27215.1 - 4.7e-12 45.8 5.6 4.7e-12 45.8 5.6 1.7 2 0 0 2 2 2 1 Fanconi Anaemia group E protein FANCE MnmE_helical PF12631.7 KDO27216.1 - 6.8e-49 166.8 0.1 8.6e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KDO27216.1 - 5.6e-29 100.8 0.0 1.1e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KDO27216.1 - 1e-20 73.9 0.1 2.3e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO27216.1 - 3.3e-10 39.7 0.1 5.4e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO27216.1 - 3.1e-05 24.1 0.0 8.2e-05 22.7 0.0 1.7 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 KDO27216.1 - 0.0024 18.4 0.0 0.011 16.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KDO27216.1 - 0.0036 17.2 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KDO27216.1 - 0.019 14.5 0.4 6.1 6.3 0.2 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KDO27216.1 - 0.062 12.7 0.1 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 KDO27216.1 - 0.11 12.0 0.2 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1_Xtn PF16897.5 KDO27216.1 - 0.12 12.4 0.3 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MoCF_biosynth PF00994.24 KDO27217.1 - 4e-26 91.4 0.0 6.1e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain U-box PF04564.15 KDO27221.1 - 1.2e-18 67.1 0.0 3.1e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 U-box domain VHL PF01847.16 KDO27221.1 - 1.2e-12 47.6 0.1 1e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 VHL beta domain zf-Nse PF11789.8 KDO27221.1 - 1.8e-05 24.5 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO27221.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1658 PF07871.11 KDO27222.1 - 2.4 8.3 8.3 0.28 11.2 1.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1658) Myotub-related PF06602.14 KDO27223.1 - 3e-103 345.4 0.0 3.1e-66 223.7 0.7 2.2 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain RabGAP-TBC PF00566.18 KDO27223.1 - 4.9e-28 98.2 0.0 2.2e-26 92.9 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 KDO27223.1 - 2.7e-05 23.9 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO27223.1 - 0.00025 21.3 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRAM PF02893.20 KDO27223.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain IRK_C PF17655.1 KDO27224.1 - 2.5e-21 76.0 0.4 1e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KDO27224.1 - 1.9e-11 43.9 7.3 3.7e-08 33.3 1.2 2.4 1 1 1 2 2 2 2 Inward rectifier potassium channel transmembrane domain SAC3_GANP PF03399.16 KDO27224.1 - 0.043 13.2 0.2 0.07 12.5 0.2 1.2 1 0 0 1 1 1 0 SAC3/GANP family Ion_trans_2 PF07885.16 KDO27224.1 - 1.6 8.8 11.5 3.3 7.7 11.0 1.8 1 1 1 2 2 2 0 Ion channel Linker_histone PF00538.19 KDO27225.1 - 2e-17 63.3 0.3 2e-17 63.3 0.3 3.1 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 KDO27225.1 - 9.5e-08 32.3 78.5 9.5e-08 32.3 78.5 2.2 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 PhoLip_ATPase_C PF16212.5 KDO27226.1 - 5.9e-66 222.8 18.5 8.3e-66 222.3 18.5 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KDO27226.1 - 1.1e-10 42.2 8.9 4.2e-05 23.9 4.6 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO27226.1 - 4e-08 33.2 0.0 2e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KDO27226.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IQ PF00612.27 KDO27227.1 - 0.00022 20.7 1.3 0.00022 20.7 1.3 4.8 3 2 0 3 3 3 2 IQ calmodulin-binding motif WW PF00397.26 KDO27228.1 - 6e-09 35.8 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 WW domain Ank_4 PF13637.6 KDO27229.1 - 0.011 16.3 0.2 0.33 11.6 0.0 2.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27229.1 - 0.015 15.6 0.1 0.7 10.3 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO27229.1 - 0.13 12.8 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Prefoldin_2 PF01920.20 KDO27231.1 - 0.0034 17.3 2.1 1.1 9.2 0.1 2.4 2 0 0 2 2 2 2 Prefoldin subunit LigT_PEase PF02834.16 KDO27231.1 - 0.024 14.8 0.7 0.064 13.4 0.7 1.8 1 0 0 1 1 1 0 LigT like Phosphoesterase TMF_TATA_bd PF12325.8 KDO27231.1 - 0.024 14.9 1.1 0.024 14.9 1.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 KDO27231.1 - 0.038 14.2 0.8 0.86 9.8 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 KDO27231.1 - 0.071 13.3 0.6 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 RasGAP C-terminus CENP-F_leu_zip PF10473.9 KDO27231.1 - 0.072 13.1 4.0 3.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 KDO27231.1 - 0.16 12.4 0.6 9.2 6.8 0.0 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Wtap PF17098.5 KDO27231.1 - 0.75 9.7 9.4 8.3 6.3 9.4 2.2 1 1 0 1 1 1 0 WTAP/Mum2p family APG6_N PF17675.1 KDO27231.1 - 1.2 9.6 13.8 10 6.7 5.5 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Lectin_N PF03954.14 KDO27231.1 - 1.3 8.7 7.6 1 9.1 1.5 2.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DivIC PF04977.15 KDO27231.1 - 4.3 7.2 11.1 27 4.6 1.3 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF2457 PF10446.9 KDO27234.1 - 0.003 16.8 2.8 0.0057 15.9 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) B2-adapt-app_C PF09066.10 KDO27236.1 - 4.6e-10 39.6 0.5 8e-10 38.8 0.5 1.3 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Ig_Tie2_1 PF10430.9 KDO27236.1 - 0.071 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 DUF5379 PF17350.2 KDO27236.1 - 5.9 7.2 7.2 31 4.9 0.9 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5379) Nop53 PF07767.11 KDO27237.1 - 7.4e-37 127.7 39.2 3.2e-35 122.3 39.2 2.1 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF569 PF04601.13 KDO27237.1 - 0.0011 18.7 0.1 0.0033 17.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF569) GCFC PF07842.12 KDO27238.1 - 5.6e-49 167.2 3.6 8.1e-49 166.7 3.6 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KDO27238.1 - 6.9e-12 45.1 0.8 1.4e-11 44.1 0.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KDO27238.1 - 4.1e-05 23.6 1.6 4.1e-05 23.6 1.6 2.5 3 0 0 3 3 3 1 G-patch domain DUF3245 PF11595.8 KDO27238.1 - 0.019 15.4 1.3 0.056 13.9 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Ion_trans PF00520.31 KDO27239.1 - 1.1e-21 77.2 8.6 1.9e-21 76.4 8.6 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO27239.1 - 1e-12 48.0 0.0 4.7e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO27239.1 - 5.9e-12 45.4 1.6 2.3e-11 43.5 1.6 2.0 1 0 0 1 1 1 1 Ion channel CopD PF05425.13 KDO27239.1 - 0.02 15.3 0.2 0.075 13.4 0.2 2.0 1 0 0 1 1 1 0 Copper resistance protein D HisKA PF00512.25 KDO27239.1 - 2.4 8.2 4.5 4.6 7.4 0.2 2.8 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain WD40 PF00400.32 KDO27240.1 - 4.4e-20 71.6 0.6 5.1e-05 24.0 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27240.1 - 1.2e-06 28.7 0.0 0.019 15.2 0.0 3.3 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO27240.1 - 0.047 13.0 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Ion_trans PF00520.31 KDO27241.1 - 3.4e-22 78.9 11.1 4.9e-22 78.4 11.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO27241.1 - 1.2e-09 38.0 4.2 3.1e-09 36.7 4.2 1.7 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 KDO27241.1 - 1.4e-08 34.7 0.0 4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IRK PF01007.20 KDO27241.1 - 1.5 8.6 7.4 1.3 8.8 0.4 2.3 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Histone PF00125.24 KDO27242.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KDO27242.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO27242.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO27242.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KDO27242.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO27242.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KDO27243.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO27243.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO27243.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO27243.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO27243.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO27243.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO27243.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated ApoL PF05461.11 KDO27244.1 - 1.1 8.5 7.0 0.84 8.9 3.1 2.0 2 0 0 2 2 2 0 Apolipoprotein L PIP5K PF01504.18 KDO27245.1 - 1.9e-39 135.6 0.0 9.7e-30 103.7 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 KDO27245.1 - 1.5e-10 41.5 0.0 3.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO27245.1 - 0.14 12.6 0.2 0.68 10.4 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain XTBD PF11952.8 KDO27245.1 - 0.15 11.8 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD Pex24p PF06398.11 KDO27245.1 - 0.89 8.5 5.2 1.5 7.8 5.2 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Myb_DNA-binding PF00249.31 KDO27246.1 - 1.1e-08 35.1 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO27246.1 - 7.9e-08 32.1 0.0 0.0045 16.9 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Vps51 PF08700.11 KDO27247.1 - 5.5e-08 32.8 0.1 1.4e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Spectrin PF00435.21 KDO27247.1 - 0.046 14.2 0.6 0.14 12.7 0.6 1.7 1 0 0 1 1 1 0 Spectrin repeat EF-hand_7 PF13499.6 KDO27248.1 - 1e-22 80.4 6.3 8.5e-10 38.9 0.2 4.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO27248.1 - 1e-19 68.5 7.4 5.4e-06 25.6 0.0 5.4 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 KDO27248.1 - 1.6e-18 66.3 8.1 0.00022 21.0 0.1 5.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KDO27248.1 - 1.8e-15 55.5 5.7 6.7e-05 22.5 0.1 5.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KDO27248.1 - 1e-09 37.4 6.5 0.00069 19.0 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 KDO27248.1 - 2e-06 27.7 4.0 3.8 7.5 0.1 5.6 4 2 2 6 6 6 2 Cytoskeletal-regulatory complex EF hand AKAP28 PF14469.6 KDO27248.1 - 0.0034 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 28 kDa A-kinase anchor SPARC_Ca_bdg PF10591.9 KDO27248.1 - 0.0048 17.2 1.0 1.5 9.2 0.3 2.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KDO27248.1 - 0.017 16.0 0.2 1.6 9.6 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain TM231 PF10149.9 KDO27248.1 - 0.14 11.5 1.3 1.7 8.0 0.0 2.5 2 1 1 3 3 3 0 Transmembrane protein 231 EF-hand_10 PF14788.6 KDO27248.1 - 0.81 9.6 4.0 3.5 7.6 0.0 3.8 4 2 1 5 5 5 0 EF hand ERF PF04404.12 KDO27248.1 - 3.5 7.5 0.0 3.5 7.5 0.0 3.5 4 0 0 4 4 3 0 ERF superfamily TTL PF03133.15 KDO27249.1 - 1.1e-51 175.7 0.0 1.5e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO27249.1 - 5.6e-06 25.8 0.0 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 KDO27249.1 - 0.00022 21.3 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Spore_YabQ PF09578.10 KDO27249.1 - 0.039 14.2 0.4 0.61 10.3 0.1 2.2 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Rox3 PF08633.10 KDO27250.1 - 0.12 12.7 2.8 0.24 11.6 1.2 2.1 2 1 0 2 2 2 0 Rox3 mediator complex subunit HAUS5 PF14817.6 KDO27250.1 - 0.14 10.9 8.2 0.17 10.6 8.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 V_ATPase_I PF01496.19 KDO27250.1 - 3.7 5.3 8.1 1.5 6.6 5.9 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.9 KDO27250.1 - 9.6 7.0 8.1 2.3 9.0 1.6 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Castor_Poll_mid PF06241.12 KDO27251.1 - 6.2e-27 93.6 0.0 1.3e-25 89.3 0.0 2.5 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 KDO27251.1 - 0.014 15.2 0.1 0.17 11.7 0.0 2.8 3 0 0 3 3 3 0 TrkA-C domain Lipase_GDSL PF00657.22 KDO27251.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Castor_Poll_mid PF06241.12 KDO27252.1 - 8.1e-27 93.2 0.0 1.6e-24 85.8 0.0 2.6 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel WD40 PF00400.32 KDO27253.1 - 6e-27 93.4 30.8 6.2e-09 36.4 0.0 11.6 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27253.1 - 1.4e-15 57.3 7.1 0.00085 19.6 0.5 5.8 4 3 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KDO27253.1 - 5.4e-05 23.2 0.0 1.3 9.1 0.0 4.8 6 0 0 6 6 6 2 Ciliary BBSome complex subunit 2, middle region tify PF06200.14 KDO27253.1 - 0.02 14.2 0.1 0.059 12.7 0.1 1.8 1 0 0 1 1 1 0 tify domain IKI3 PF04762.12 KDO27253.1 - 0.065 11.2 0.4 0.6 8.0 0.0 2.3 2 0 0 2 2 2 0 IKI3 family TPR_2 PF07719.17 KDO27253.1 - 0.16 12.2 2.5 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO27253.1 - 0.17 11.7 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PALB2_WD40 PF16756.5 KDO27253.1 - 0.21 10.4 1.4 0.98 8.3 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ank_2 PF12796.7 KDO27255.1 - 1.6e-21 76.6 14.6 6e-05 23.6 0.2 6.4 2 2 6 8 8 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27255.1 - 7.1e-16 58.4 16.8 0.005 17.4 0.0 8.0 7 1 3 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27255.1 - 9.7e-10 37.9 16.3 2.1 9.1 0.0 11.9 14 0 0 14 14 14 1 Ankyrin repeat Ank_5 PF13857.6 KDO27255.1 - 5.3e-06 26.6 16.7 6.7 7.2 0.0 9.5 4 1 7 11 11 11 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 KDO27255.1 - 8.8e-05 22.3 0.0 1.1 9.2 0.0 5.0 4 0 0 4 4 4 1 Domain of unknown function (DUF5049) DUF3447 PF11929.8 KDO27255.1 - 0.015 15.2 0.0 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Ank PF00023.30 KDO27255.1 - 0.056 13.9 15.7 12 6.5 0.2 7.9 7 3 1 8 8 8 0 Ankyrin repeat HTH_22 PF13309.6 KDO27255.1 - 0.11 12.5 0.0 8.8 6.5 0.0 3.1 2 0 0 2 2 2 0 HTH domain PH PF00169.29 KDO27256.1 - 2.8e-22 79.2 3.4 3.7e-10 40.3 0.1 5.4 4 2 0 4 4 4 4 PH domain PH_8 PF15409.6 KDO27256.1 - 2.4e-06 27.7 2.2 0.0024 18.1 0.1 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 KDO27256.1 - 3.2e-06 27.5 4.5 0.61 10.5 0.1 4.1 3 1 0 3 3 3 2 Pleckstrin homology domain BRX_assoc PF16627.5 KDO27256.1 - 0.056 13.6 1.9 0.15 12.2 1.2 2.1 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain CHORD PF04968.12 KDO27257.1 - 0.00033 21.3 3.0 0.00033 21.3 3.0 1.9 2 0 0 2 2 2 1 CHORD GIT_CC PF16559.5 KDO27257.1 - 0.0079 16.0 1.5 0.0079 16.0 1.5 5.3 4 1 0 5 5 5 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1059 PF06348.11 KDO27257.1 - 0.055 13.7 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) ATG16 PF08614.11 KDO27257.1 - 0.18 12.0 55.0 1.8 8.8 26.1 4.0 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 KDO27257.1 - 0.56 10.6 25.7 0.33 11.4 1.9 6.3 5 1 0 6 6 6 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 KDO27257.1 - 4.8 7.0 57.0 0.35 10.7 17.6 3.7 2 2 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GYF_2 PF14237.6 KDO27258.1 - 3.5e-16 58.7 0.7 9.2e-09 35.0 0.2 3.0 3 0 0 3 3 3 2 GYF domain 2 RRM_1 PF00076.22 KDO27258.1 - 4.4e-10 39.2 0.0 0.00027 20.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_PP31 PF05311.11 KDO27258.1 - 0.022 14.2 0.8 0.04 13.4 0.8 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PIEZO PF15917.5 KDO27258.1 - 0.097 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Piezo RRM_7 PF16367.5 KDO27258.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RNA_pol_Rbc25 PF08292.12 KDO27258.1 - 0.67 10.2 2.5 1.7 8.9 2.5 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 PX PF00787.24 KDO27259.1 - 5.4e-11 42.5 0.0 8.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 PX domain tRNA-synt_1d PF00750.19 KDO27260.1 - 1.2e-113 379.6 0.1 1.8e-113 379.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KDO27260.1 - 3.2e-24 85.4 0.1 7.2e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KDO27260.1 - 7e-18 65.0 0.0 1.5e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C PF00043.25 KDO27260.1 - 0.00033 20.8 0.1 0.00081 19.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO27260.1 - 0.00091 19.2 0.1 0.0027 17.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO27260.1 - 0.0023 18.1 0.0 0.0078 16.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1g PF09334.11 KDO27260.1 - 0.0045 15.8 0.1 0.0075 15.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KDO27260.1 - 0.0071 15.7 0.2 0.024 14.0 0.2 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KDO27260.1 - 0.015 13.6 0.2 0.029 12.6 0.1 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) fn3 PF00041.21 KDO27261.1 - 6.3e-10 39.3 15.0 1.7 9.1 0.0 10.3 10 0 0 10 10 10 2 Fibronectin type III domain cEGF PF12662.7 KDO27261.1 - 0.012 15.5 0.6 0.012 15.5 0.6 3.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KDO27261.1 - 0.054 13.8 9.3 0.028 14.7 3.3 2.5 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KDO27261.1 - 0.56 10.6 2.8 8.7 6.7 0.6 2.4 2 0 0 2 2 2 0 Pvs28 EGF domain Tme5_EGF_like PF09064.10 KDO27261.1 - 0.81 9.6 11.5 1.2 9.1 0.9 2.6 1 1 1 2 2 2 0 Thrombomodulin like fifth domain, EGF-like EGF_2 PF07974.13 KDO27261.1 - 9.2 6.7 6.9 57 4.2 3.1 2.7 2 0 0 2 2 2 0 EGF-like domain HEAT_EZ PF13513.6 KDO27262.1 - 0.025 15.1 2.0 8.8 7.0 0.1 3.5 3 0 0 3 3 3 0 HEAT-like repeat DUF3677 PF12432.8 KDO27262.1 - 0.09 13.1 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Dopey_N PF04118.14 KDO27262.1 - 0.19 10.8 1.8 14 4.7 0.0 3.3 2 1 0 3 3 3 0 Dopey, N-terminal MORN PF02493.20 KDO27263.1 - 1.8e-73 238.3 106.0 1.8e-07 30.7 4.7 17.7 18 0 0 18 18 18 15 MORN repeat IQ PF00612.27 KDO27263.1 - 0.0018 17.9 2.9 1.6 8.7 0.9 3.2 2 0 0 2 2 2 2 IQ calmodulin-binding motif OrsD PF12013.8 KDO27263.1 - 0.86 10.1 5.6 0.17 12.3 0.4 2.4 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3048_C PF17479.2 KDO27263.1 - 9 6.7 24.0 2.3 8.6 0.1 7.1 2 2 6 9 9 9 0 Protein of unknown function (DUF3048) C-terminal domain FYVE PF01363.21 KDO27264.1 - 4.5e-13 49.1 12.8 1.7e-12 47.3 12.9 1.8 1 1 1 2 2 2 2 FYVE zinc finger DUSP PF06337.12 KDO27264.1 - 7.8e-13 48.9 0.0 1.6e-12 47.9 0.0 1.5 2 0 0 2 2 2 1 DUSP domain FYVE_2 PF02318.16 KDO27264.1 - 0.00053 20.2 6.3 0.00089 19.5 6.3 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_2 PF14445.6 KDO27264.1 - 0.85 9.8 10.3 2.6 8.3 10.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Cupin_8 PF13621.6 KDO27265.1 - 1.9e-55 188.4 0.0 2.4e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO27265.1 - 0.00016 21.2 0.0 0.21 11.0 0.0 2.5 2 0 0 2 2 2 2 Cupin superfamily protein SDA1 PF05285.12 KDO27265.1 - 1.7 8.0 11.4 2.4 7.5 11.4 1.1 1 0 0 1 1 1 0 SDA1 TPR_1 PF00515.28 KDO27266.1 - 3e-33 112.2 20.3 5.3e-06 26.0 1.2 9.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27266.1 - 1.8e-28 96.3 19.3 2.9e-06 27.0 0.0 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.31 KDO27266.1 - 9.2e-24 83.4 3.6 9.2e-24 83.4 3.6 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 KDO27266.1 - 1.7e-21 75.6 20.9 3.6e-06 26.6 1.0 8.3 6 3 3 9 9 9 5 TPR repeat TPR_8 PF13181.6 KDO27266.1 - 3.7e-17 61.0 19.2 0.0097 16.0 0.0 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27266.1 - 9.1e-15 54.9 15.2 9e-06 26.1 0.0 5.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27266.1 - 2e-14 53.1 12.1 0.0069 17.1 0.0 7.6 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO27266.1 - 2.7e-14 53.5 18.4 0.003 18.2 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO27266.1 - 1.9e-13 49.7 10.9 0.16 12.4 1.4 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27266.1 - 8.9e-10 38.7 20.3 0.002 18.4 1.3 6.4 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO27266.1 - 2.3e-08 33.5 13.4 0.5 10.5 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO27266.1 - 7.7e-07 29.2 7.4 0.6 10.3 0.0 6.3 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO27266.1 - 1.5e-05 25.3 19.1 0.004 17.7 0.0 6.5 7 0 0 7 7 5 2 Tetratricopeptide repeat BTAD PF03704.17 KDO27266.1 - 0.0017 18.8 9.2 0.027 14.9 0.3 3.8 2 1 1 3 3 3 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KDO27266.1 - 0.0024 18.1 0.2 0.0024 18.1 0.2 4.6 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KDO27266.1 - 0.0046 17.0 0.0 1.2 9.3 0.0 3.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 KDO27266.1 - 0.014 14.6 1.5 0.03 13.5 0.3 2.0 1 1 0 1 1 1 0 FAT domain Alkyl_sulf_dimr PF14863.6 KDO27266.1 - 0.038 14.4 7.5 16 5.9 0.2 4.4 2 1 3 5 5 5 0 Alkyl sulfatase dimerisation Forkhead_N PF08430.12 KDO27266.1 - 0.1 13.2 2.3 0.2 12.3 2.3 1.5 1 0 0 1 1 1 0 Forkhead N-terminal region DUF3856 PF12968.7 KDO27266.1 - 0.15 12.1 9.1 1.1 9.3 1.0 5.2 4 2 2 6 6 6 0 Domain of Unknown Function (DUF3856) MAS20 PF02064.15 KDO27266.1 - 0.17 12.0 8.4 1.3 9.2 0.0 4.2 4 1 0 4 4 4 0 MAS20 protein import receptor SRP_TPR_like PF17004.5 KDO27266.1 - 0.19 11.8 0.0 0.19 11.8 0.0 4.1 3 1 0 4 4 4 0 Putative TPR-like repeat MIT PF04212.18 KDO27266.1 - 1.8 8.7 14.4 5.7 7.1 0.1 6.2 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KDO27266.1 - 7.3 6.7 9.3 17 5.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Endonuclease_5 PF04493.14 KDO27267.1 - 1.4e-57 194.6 0.0 1.7e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 KDO27267.1 - 0.052 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF99 UvrC_HhH_N PF08459.11 KDO27267.1 - 0.058 13.3 0.0 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal SH2_2 PF14633.6 KDO27268.1 - 1.6e-44 151.9 1.4 4.4e-44 150.5 1.4 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 KDO27268.1 - 9.7e-17 61.2 0.2 2.1e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KDO27268.1 - 5.1e-13 49.4 21.5 5.1e-13 49.4 21.5 6.1 3 1 2 5 5 5 2 Acidic N-terminal SPT6 YqgF PF14639.6 KDO27268.1 - 2.2e-12 47.0 0.0 6.6e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KDO27268.1 - 7.1e-11 42.6 0.1 1.9e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_9 PF17674.1 KDO27268.1 - 6.2e-07 30.2 0.4 0.00029 21.7 0.4 3.5 1 1 0 1 1 1 1 HHH domain Tex_N PF09371.10 KDO27268.1 - 8e-06 25.6 0.0 0.00094 18.9 0.0 2.8 1 1 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KDO27268.1 - 0.0003 21.2 0.0 0.001 19.5 0.0 2.0 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 KDO27268.1 - 0.0007 19.8 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pex2_Pex12 PF04757.14 KDO27269.1 - 1e-23 84.2 0.6 1.2e-23 83.9 0.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 KDO27269.1 - 1.4e-05 24.9 8.3 2.4e-05 24.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO27269.1 - 0.00021 21.1 3.9 0.00038 20.2 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO27269.1 - 0.00028 20.8 7.4 0.00047 20.1 7.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KDO27269.1 - 0.00093 19.0 6.4 0.0029 17.4 6.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO27269.1 - 0.0019 18.5 5.6 0.0039 17.5 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO27269.1 - 0.053 13.4 3.5 0.1 12.5 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO27269.1 - 0.11 12.8 3.4 0.22 11.8 3.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO27269.1 - 0.47 10.5 8.3 0.43 10.7 6.2 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO27269.1 - 1.1 9.5 8.3 2.1 8.6 8.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING COPI_assoc PF08507.10 KDO27270.1 - 0.0047 17.0 14.2 0.01 15.9 14.2 1.5 1 1 0 1 1 1 1 COPI associated protein YtpI PF14007.6 KDO27270.1 - 0.0071 16.5 2.9 0.0071 16.5 2.9 2.0 2 0 0 2 2 2 1 YtpI-like protein DUF3341 PF11821.8 KDO27270.1 - 7.7 6.1 7.5 0.55 9.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Abhydrolase_3 PF07859.13 KDO27271.1 - 1.4e-36 126.4 0.5 1.7e-36 126.1 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KDO27271.1 - 8.9e-20 70.9 0.0 3.7e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KDO27271.1 - 0.0025 17.3 0.1 0.0052 16.3 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO27271.1 - 0.0073 15.6 0.3 0.084 12.1 0.1 2.3 2 1 1 3 3 3 1 Serine aminopeptidase, S33 MMS19_N PF14500.6 KDO27272.1 - 0.0035 17.0 0.8 0.0081 15.8 0.8 1.7 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Fes1 PF08609.10 KDO27272.1 - 0.027 15.3 0.3 0.085 13.7 0.3 1.9 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 SIP1 PF04938.12 KDO27272.1 - 0.16 11.6 2.0 0.25 11.1 0.3 2.0 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) TLD PF07534.16 KDO27273.1 - 2.6e-33 115.2 0.0 3.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 TLD LysM PF01476.20 KDO27273.1 - 4.9e-07 29.7 0.0 9.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF1942 PF09167.11 KDO27273.1 - 0.13 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) zf-CCCH PF00642.24 KDO27275.1 - 2.6e-13 49.5 17.4 1.6e-07 31.1 2.3 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO27275.1 - 0.0001 23.0 3.8 0.13 13.0 0.2 2.2 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 KDO27275.1 - 0.00013 21.8 0.1 0.00031 20.5 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KDO27275.1 - 0.0036 17.5 1.5 2.5 8.4 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 KDO27275.1 - 0.0049 16.9 21.7 0.0065 16.5 2.3 3.0 3 0 0 3 3 3 2 Zinc finger domain IFRD PF05004.13 KDO27276.1 - 1.3e-54 185.5 2.7 2e-54 184.8 2.7 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KDO27276.1 - 5.7e-06 26.1 3.1 0.035 14.4 0.2 3.5 3 1 1 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KDO27276.1 - 0.022 15.1 0.4 7.6 7.0 0.1 2.6 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 KDO27276.1 - 0.08 13.5 1.9 1 10.0 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat UDPGT PF00201.18 KDO27278.1 - 6.3e-26 91.2 0.2 8.3e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KDO27278.1 - 1.6e-07 31.4 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 KDO27278.1 - 0.00089 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.6 KDO27278.1 - 0.016 14.5 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 1 Pkinase PF00069.25 KDO27279.1 - 2.5e-69 233.6 0.0 3.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27279.1 - 3.9e-38 131.2 0.0 5.6e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27279.1 - 1.4e-09 37.7 0.0 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO27279.1 - 0.0046 15.8 0.0 0.0096 14.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO27279.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO27279.1 - 0.045 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PX PF00787.24 KDO27280.1 - 9.6e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 PX domain PAN_4 PF14295.6 KDO27281.1 - 4e-25 87.5 56.2 1.7e-08 34.2 6.6 5.6 5 1 0 5 5 5 4 PAN domain PAN_1 PF00024.26 KDO27281.1 - 4.6e-15 55.3 35.0 0.00013 21.9 4.3 5.1 2 1 3 5 5 5 4 PAN domain CAP PF00188.26 KDO27281.1 - 5.5e-11 43.4 6.4 5.5e-11 43.4 6.4 2.4 2 1 1 3 3 3 1 Cysteine-rich secretory protein family PAN_3 PF08277.12 KDO27281.1 - 5.3e-08 32.6 38.0 0.0087 15.9 2.8 5.5 5 0 0 5 5 5 4 PAN-like domain DUF5064 PF16703.5 KDO27282.1 - 0.074 13.5 0.2 0.13 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5064) CENP-Q PF13094.6 KDO27282.1 - 0.12 12.6 0.8 0.12 12.6 0.8 2.8 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 KDO27282.1 - 0.24 10.7 10.6 0.34 10.2 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Swi5 PF07061.11 KDO27282.1 - 0.36 11.0 3.3 1.6 8.8 0.2 2.5 2 0 0 2 2 2 0 Swi5 Ribosomal_L30_N PF08079.12 KDO27282.1 - 6.3 7.1 10.8 0.23 11.8 0.6 2.8 2 1 1 3 3 3 0 Ribosomal L30 N-terminal domain Meckelin PF09773.9 KDO27283.1 - 2.8e-123 412.8 0.0 1.2e-122 410.7 0.0 2.0 1 1 0 1 1 1 1 Meckelin (Transmembrane protein 67) NCD3G PF07562.14 KDO27283.1 - 0.18 11.8 6.5 0.65 10.0 0.4 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Peptidase_U4 PF03419.13 KDO27283.1 - 4.3 6.6 6.3 2 7.6 1.9 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA cEGF PF12662.7 KDO27283.1 - 6.4 6.8 6.5 4 7.5 0.3 3.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like PRKCSH PF07915.13 KDO27284.1 - 5.4e-08 33.7 3.8 1.9e-07 32.0 3.8 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KDO27284.1 - 1.6e-06 27.9 1.8 2.6e-06 27.2 1.8 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.14 KDO27284.1 - 1.1e-05 25.6 0.0 0.0071 16.5 0.0 2.6 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RD3 PF14473.6 KDO27284.1 - 0.057 13.3 0.1 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 RD3 protein zinc-ribbon_6 PF10005.9 KDO27284.1 - 0.092 13.4 2.4 2.5 8.8 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_17 PF00332.18 KDO27285.1 - 2.2e-07 30.8 1.3 0.00013 21.7 0.1 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.18 KDO27286.1 - 5.3e-15 55.8 0.4 1e-08 35.2 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2401 PF10287.9 KDO27287.1 - 7.3e-39 133.7 0.0 9.8e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KDO27287.1 - 2e-17 63.4 0.1 5.5e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) PAN_4 PF14295.6 KDO27287.1 - 3e-06 27.0 5.6 8.6e-06 25.6 5.6 1.8 1 0 0 1 1 1 1 PAN domain DUF2401 PF10287.9 KDO27288.1 - 4e-41 141.1 0.0 4e-41 141.1 0.0 1.8 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) PAN_4 PF14295.6 KDO27288.1 - 1.9e-12 46.9 30.6 6.9e-05 22.7 4.2 4.1 4 0 0 4 4 4 3 PAN domain PAN_1 PF00024.26 KDO27288.1 - 4.2e-10 39.4 14.0 0.0014 18.6 0.2 3.5 1 1 2 3 3 3 3 PAN domain DUF2403 PF10290.9 KDO27288.1 - 1.4e-09 38.3 0.1 4.5e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) PAN_3 PF08277.12 KDO27288.1 - 0.0011 18.7 21.0 0.0031 17.3 1.7 3.6 3 0 0 3 3 3 2 PAN-like domain PPDFL PF15060.6 KDO27288.1 - 0.16 12.5 2.7 9.5 6.8 0.8 3.0 2 1 0 2 2 2 0 Differentiation and proliferation regulator FH2 PF02181.23 KDO27289.1 - 5.2e-38 131.1 0.0 9.7e-38 130.2 0.0 1.4 1 1 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 KDO27289.1 - 9.9e-12 45.5 0.0 1.7e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex PAN_2 PF08276.11 KDO27290.1 - 0.0077 16.3 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KDO27290.1 - 0.18 11.7 0.9 0.41 10.6 0.9 1.5 1 0 0 1 1 1 0 PAN domain AAA_33 PF13671.6 KDO27292.1 - 2.2e-10 40.8 0.5 4.1e-08 33.5 0.0 3.0 2 2 0 2 2 2 1 AAA domain KTI12 PF08433.10 KDO27292.1 - 1.6e-09 37.6 0.0 3.8e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KDO27292.1 - 5.4e-05 23.8 0.0 0.0047 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO27292.1 - 8e-05 23.1 0.0 0.00028 21.3 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO27292.1 - 0.00056 20.2 0.2 0.012 15.9 0.0 3.0 2 2 2 4 4 4 1 AAA domain AAA_17 PF13207.6 KDO27292.1 - 0.00064 20.2 0.0 0.011 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain EH_Signature PF15611.6 KDO27292.1 - 0.0011 18.5 1.1 0.0015 18.1 1.1 1.2 1 0 0 1 1 1 1 EH_Signature domain AAA_16 PF13191.6 KDO27292.1 - 0.0032 17.9 4.3 0.0099 16.3 0.3 3.1 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KDO27292.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KDO27292.1 - 0.0068 15.7 0.0 0.026 13.8 0.0 2.0 1 1 1 2 2 2 1 Zeta toxin CPT PF07931.12 KDO27292.1 - 0.011 15.6 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ubiquitin_4 PF18036.1 KDO27292.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain ABC_tran PF00005.27 KDO27292.1 - 0.022 15.3 0.1 0.66 10.5 0.0 2.6 3 0 0 3 3 2 0 ABC transporter NACHT PF05729.12 KDO27292.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KDO27292.1 - 0.041 13.9 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KDO27292.1 - 0.066 13.3 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KDO27292.1 - 0.071 13.5 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KDO27292.1 - 0.11 12.3 3.8 0.17 11.6 0.1 3.0 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO27292.1 - 0.19 11.4 0.0 0.71 9.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain PhoD PF09423.10 KDO27295.1 - 9.7e-22 77.5 0.0 5.7e-21 74.9 0.0 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase WD40 PF00400.32 KDO27296.1 - 1.4e-49 165.0 10.8 1.1e-10 41.9 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KDO27296.1 - 1.2e-35 122.6 3.1 2.1e-35 121.8 3.1 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KDO27296.1 - 2.9e-10 40.3 0.0 0.0011 19.2 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KDO27296.1 - 4.8e-06 25.3 0.3 1e-05 24.3 0.1 1.5 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 KDO27296.1 - 0.0002 20.1 3.3 0.071 11.7 0.0 4.3 2 2 2 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KDO27296.1 - 0.0012 18.2 0.0 0.96 8.7 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 KDO27296.1 - 0.022 14.6 0.0 0.62 9.9 0.0 2.9 1 1 3 4 4 4 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KDO27296.1 - 0.039 12.9 0.1 2.7 6.9 0.0 3.1 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATE_C PF04377.15 KDO27297.1 - 6.8e-41 140.0 0.8 1.2e-40 139.3 0.8 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KDO27297.1 - 2.9e-20 72.4 0.3 6.8e-20 71.3 0.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Cupin_8 PF13621.6 KDO27298.1 - 8e-29 101.1 0.0 1.3e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO27298.1 - 6.2e-07 29.2 0.2 1.1e-06 28.4 0.1 1.4 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KDO27298.1 - 0.02 15.3 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Glyoxalase PF00903.25 KDO27301.1 - 2e-12 47.4 0.0 2.3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO27301.1 - 3.9e-08 34.0 0.1 4.8e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KDO27301.1 - 1.7e-07 31.1 0.0 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KDO27301.1 - 0.021 14.9 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KDO27301.1 - 0.024 14.9 0.0 0.37 11.1 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Arm PF00514.23 KDO27302.1 - 0.0016 18.5 2.0 0.058 13.5 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KDO27302.1 - 0.0033 16.9 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 2 Armadillo-like V-ATPase_H_C PF11698.8 KDO27302.1 - 0.005 16.9 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.22 KDO27302.1 - 0.035 14.4 2.3 0.25 11.7 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Adaptin_N PF01602.20 KDO27302.1 - 0.085 11.4 0.2 1.3 7.5 0.0 2.4 2 1 1 3 3 3 0 Adaptin N terminal region HEAT_2 PF13646.6 KDO27302.1 - 0.41 11.1 10.2 0.34 11.3 0.7 2.7 1 1 1 2 2 2 0 HEAT repeats Abhydrolase_1 PF00561.20 KDO27303.1 - 1.2e-09 38.3 0.0 8.7e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO27303.1 - 7.9e-06 25.3 0.1 0.0001 21.7 0.1 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO27303.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KDO27303.1 - 0.023 14.2 0.0 0.85 9.0 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family PLRV_ORF5 PF01690.17 KDO27303.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PX PF00787.24 KDO27305.1 - 3.1e-21 75.5 0.0 5.3e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KDO27305.1 - 3.4e-07 30.1 0.2 6.9e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Vps5 C terminal like Alpha-E PF04168.12 KDO27305.1 - 0.012 15.5 0.8 0.012 15.5 0.8 1.6 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. Thymidylat_synt PF00303.19 KDO27305.1 - 0.076 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Thymidylate synthase RRN3 PF05327.11 KDO27306.1 - 0.0023 16.5 12.4 0.003 16.2 12.4 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KDO27306.1 - 0.1 12.0 21.5 0.13 11.7 21.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KDO27306.1 - 0.3 9.3 22.4 0.4 8.8 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 KDO27306.1 - 0.33 11.0 14.0 0.62 10.1 14.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 KDO27306.1 - 0.62 9.9 13.2 1.2 9.0 13.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region POX PF07526.11 KDO27306.1 - 1.1 9.8 3.1 2.2 8.9 3.1 1.4 1 0 0 1 1 1 0 Associated with HOX UPF0176_N PF17773.1 KDO27308.1 - 1.6e-20 73.3 0.0 3.9e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 KDO27308.1 - 1.9e-12 47.4 6.4 1.9e-12 47.4 6.4 2.4 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 KDO27308.1 - 4.3e-11 43.3 0.0 8.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FYVE PF01363.21 KDO27308.1 - 0.02 15.0 9.5 0.58 10.3 0.5 2.6 2 0 0 2 2 2 0 FYVE zinc finger DUF4570 PF15134.6 KDO27308.1 - 0.038 14.0 1.3 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Anti-adapt_IraP PF10796.9 KDO27308.1 - 0.17 12.4 0.3 0.36 11.4 0.3 1.5 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein Myotub-related PF06602.14 KDO27310.1 - 2e-104 349.3 0.0 2.8e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain VPS13_C PF16909.5 KDO27310.1 - 0.0011 18.8 1.6 0.0018 18.1 1.6 1.2 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Y_phosphatase3 PF13350.6 KDO27310.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family IQ PF00612.27 KDO27312.1 - 6.5e-09 34.8 57.9 0.0034 17.0 1.0 8.8 8 0 0 8 8 8 6 IQ calmodulin-binding motif LRR_4 PF12799.7 KDO27312.1 - 6.8e-08 32.7 1.4 0.15 12.5 0.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO27312.1 - 8.8e-05 22.3 12.4 3.6 7.9 0.0 6.9 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 KDO27312.1 - 0.033 14.0 0.1 11 5.9 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat UPF0731 PF14982.6 KDO27312.1 - 0.13 12.4 3.6 5 7.4 0.2 3.3 3 0 0 3 3 3 0 UPF0731 family Agenet PF05641.12 KDO27312.1 - 0.17 12.4 0.5 2.5 8.6 0.0 2.9 2 0 0 2 2 2 0 Agenet domain LRR_1 PF00560.33 KDO27312.1 - 0.87 10.4 6.6 56 4.9 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat TIR_2 PF13676.6 KDO27313.1 - 2e-13 51.0 0.0 4.4e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 TIR domain BTK PF00779.19 KDO27313.1 - 0.0084 15.9 0.4 0.024 14.5 0.4 1.8 1 0 0 1 1 1 1 BTK motif LRR_8 PF13855.6 KDO27314.1 - 1.6e-13 50.2 10.3 3.8e-08 33.0 1.7 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KDO27314.1 - 4.8e-08 33.2 20.2 0.0078 16.6 0.2 5.2 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO27314.1 - 2.6e-07 30.3 2.4 7.1e-07 28.9 2.4 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KDO27314.1 - 1.2e-05 25.0 21.0 3.3 8.0 0.0 7.5 7 0 0 7 7 7 3 Leucine Rich repeat WW PF00397.26 KDO27314.1 - 0.00012 22.1 5.7 0.00022 21.2 5.7 1.5 1 0 0 1 1 1 1 WW domain EF-hand_6 PF13405.6 KDO27314.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Baculo_PEP_C PF04513.12 KDO27315.1 - 3.1e-06 27.3 9.9 0.0056 16.7 0.2 4.5 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus HalX PF08663.10 KDO27315.1 - 0.0057 16.9 1.3 0.0057 16.9 1.3 4.8 4 1 0 4 4 4 1 HalX domain Occludin_ELL PF07303.13 KDO27315.1 - 0.026 15.3 14.4 0.29 11.9 0.3 4.4 2 1 3 5 5 5 0 Occludin homology domain Golgin_A5 PF09787.9 KDO27315.1 - 0.035 13.6 27.9 0.11 12.0 15.0 3.8 2 1 1 4 4 4 0 Golgin subfamily A member 5 GIDA PF01134.22 KDO27315.1 - 0.062 12.4 1.9 0.12 11.4 1.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4407 PF14362.6 KDO27315.1 - 0.087 12.2 22.1 1e+03 -1.2 22.0 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COMM_domain PF07258.14 KDO27315.1 - 0.1 12.7 0.7 6.2 7.0 0.0 3.3 2 0 0 2 2 2 0 COMM domain DUF1664 PF07889.12 KDO27315.1 - 0.14 12.2 17.4 0.88 9.6 3.9 4.5 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KDO27315.1 - 0.17 11.7 41.4 0.97 9.3 11.8 4.2 2 2 1 3 3 3 0 Apolipoprotein A1/A4/E domain DnaB_C PF03796.15 KDO27315.1 - 0.32 10.3 4.5 0.053 12.9 0.4 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Gp58 PF07902.11 KDO27315.1 - 0.42 8.9 5.4 0.73 8.1 5.4 1.4 1 0 0 1 1 1 0 gp58-like protein Syntaxin PF00804.25 KDO27315.1 - 0.53 9.9 18.5 0.36 10.5 0.5 3.5 1 1 2 3 3 3 0 Syntaxin ORF6C PF10552.9 KDO27315.1 - 0.69 10.0 6.1 1.1 9.4 0.5 3.2 3 1 0 3 3 3 0 ORF6C domain zf-ZPR1 PF03367.13 KDO27315.1 - 0.98 9.3 6.6 2.9 7.8 0.7 3.3 2 2 2 4 4 4 0 ZPR1 zinc-finger domain DUF4795 PF16043.5 KDO27315.1 - 1.1 8.8 23.5 0.066 12.8 1.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) CLZ PF16526.5 KDO27315.1 - 1.7 9.1 26.0 4.4 7.7 1.9 6.0 3 1 4 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4665 PF15679.5 KDO27315.1 - 1.8 9.2 6.7 1.6 9.4 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) Mt_ATP-synt_D PF05873.12 KDO27315.1 - 3.1 7.6 8.8 0.39 10.5 1.9 2.8 3 1 1 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) ACCA PF03255.14 KDO27315.1 - 4 7.3 16.3 16 5.4 0.1 4.6 4 1 1 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Seryl_tRNA_N PF02403.22 KDO27315.1 - 4.1 7.7 14.0 2.1 8.6 3.4 4.0 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain zf-RING_2 PF13639.6 KDO27316.1 - 1e-11 44.9 9.3 2.1e-11 44.0 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO27316.1 - 1.3e-09 37.7 9.6 2.8e-09 36.7 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO27316.1 - 2.2e-09 37.5 8.2 5.6e-09 36.1 8.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO27316.1 - 7.1e-06 25.8 8.2 1.4e-05 24.9 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO27316.1 - 3e-05 23.8 5.6 5.4e-05 23.0 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO27316.1 - 8.4e-05 22.5 5.8 0.00017 21.5 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO27316.1 - 0.0001 22.0 7.6 0.0001 22.0 7.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO27316.1 - 0.00078 19.3 7.1 0.0015 18.5 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO27316.1 - 0.00084 19.3 6.0 0.002 18.1 6.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO27316.1 - 0.0028 17.5 7.5 0.0051 16.6 7.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO27316.1 - 0.0029 17.7 2.6 0.0057 16.8 2.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-HC5HC2H_2 PF13832.6 KDO27316.1 - 0.0044 17.2 0.4 0.01 16.0 0.4 1.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain Vps39_2 PF10367.9 KDO27316.1 - 0.0046 17.4 1.9 0.025 15.0 0.1 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KDO27316.1 - 0.0087 15.7 7.0 0.018 14.7 7.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type UPF0547 PF10571.9 KDO27316.1 - 0.092 12.8 0.1 0.092 12.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_4 PF15227.6 KDO27316.1 - 0.28 11.4 6.5 0.64 10.2 6.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KDO27316.1 - 0.3 11.2 4.5 0.9 9.6 4.5 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 KDO27316.1 - 0.8 9.5 4.1 1.9 8.3 4.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 KDO27316.1 - 0.86 9.8 5.6 2.3 8.4 5.7 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.7 KDO27316.1 - 1.4 9.1 7.6 3.4 7.9 7.6 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO27316.1 - 2.2 8.5 7.5 16 5.8 7.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KDO27316.1 - 3.1 8.2 7.7 10 6.5 7.7 2.0 1 1 0 1 1 1 0 RING-like domain Neurochondrin PF05536.11 KDO27317.1 - 2.3e-43 148.5 1.5 7.7e-42 143.5 1.5 2.0 1 1 0 1 1 1 1 Neurochondrin NCD3G PF07562.14 KDO27319.1 - 0.11 12.5 3.7 0.22 11.5 3.7 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR zf-RanBP PF00641.18 KDO27319.1 - 0.53 9.7 10.8 0.083 12.2 5.9 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Rubredoxin_2 PF18073.1 KDO27319.1 - 0.6 9.9 8.4 4.4 7.1 4.6 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn-ribbon_8 PF09723.10 KDO27319.1 - 4.5 7.5 8.6 7.5 6.8 1.0 3.3 2 1 1 3 3 3 0 Zinc ribbon domain DUF389 PF04087.14 KDO27320.1 - 2.7e-38 131.2 10.6 5.3e-38 130.3 10.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF389) PHO4 PF01384.20 KDO27320.1 - 0.041 12.9 9.5 0.058 12.4 9.5 1.2 1 0 0 1 1 1 0 Phosphate transporter family DUF441 PF04284.13 KDO27320.1 - 0.089 12.8 10.6 0.058 13.4 6.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF441) Peptidase_M14 PF00246.24 KDO27321.1 - 9e-15 55.2 0.0 2.6e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KDO27321.1 - 8.1e-05 22.9 0.1 0.00024 21.4 0.1 1.9 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KDO27321.1 - 0.038 13.1 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Dynein_light PF01221.18 KDO27322.1 - 2.2e-26 92.0 1.8 2.5e-26 91.8 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 NnrU PF07298.11 KDO27323.1 - 6e-12 45.5 0.3 8.4e-11 41.8 0.3 2.0 1 1 0 1 1 1 1 NnrU protein RNB PF00773.19 KDO27323.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 RNB domain zf-Tim10_DDP PF02953.15 KDO27324.1 - 1.7e-19 69.2 3.5 2.5e-19 68.7 3.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KDO27324.1 - 0.023 14.4 3.6 0.063 13.0 3.5 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Herpes_TK_C PF08465.10 KDO27324.1 - 0.044 13.5 0.3 0.092 12.5 0.0 1.7 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal AA_kinase PF00696.28 KDO27325.1 - 5.8e-15 55.5 0.2 7.3e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 KDO27325.1 - 3.7e-08 33.6 0.0 7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO27325.1 - 2.3e-06 27.9 0.0 5.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO27325.1 - 1.2e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_9 PF12781.7 KDO27325.1 - 0.0076 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region Acetyltransf_6 PF13480.7 KDO27325.1 - 0.046 13.9 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CLIP_1 PF18322.1 KDO27325.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 Serine protease Clip domain PPAF-2 LNP1 PF15419.6 KDO27327.1 - 0.096 12.9 0.2 0.16 12.2 0.2 1.3 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 EF-hand_7 PF13499.6 KDO27328.1 - 3.3e-48 162.0 27.1 2.6e-10 40.6 0.1 8.0 8 0 0 8 8 8 7 EF-hand domain pair EF-hand_6 PF13405.6 KDO27328.1 - 2.7e-47 154.7 27.2 2.5e-05 23.8 0.2 13.2 14 0 0 14 14 14 10 EF-hand domain EF-hand_1 PF00036.32 KDO27328.1 - 3.9e-43 141.8 28.5 2.4e-05 23.6 0.2 13.3 13 0 0 13 13 13 10 EF hand EF-hand_5 PF13202.6 KDO27328.1 - 1e-29 100.7 21.8 0.00019 20.7 0.0 11.2 11 0 0 11 11 11 8 EF hand EF-hand_8 PF13833.6 KDO27328.1 - 2.4e-24 84.9 30.8 4.4e-10 39.3 0.3 10.9 10 3 3 13 13 13 6 EF-hand domain pair EF-hand_9 PF14658.6 KDO27328.1 - 4.7e-05 23.6 7.3 4.3 7.7 0.2 6.1 6 0 0 6 6 6 3 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO27328.1 - 9.4e-05 22.7 0.0 8.6 6.7 0.0 4.9 5 1 0 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3392 PF11872.8 KDO27331.1 - 7.3 6.9 9.5 6.2 7.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3392) TPD PF14811.6 KDO27332.1 - 1.1e-29 103.1 0.0 2.2e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif PPR_long PF17177.4 KDO27332.1 - 0.026 13.9 0.0 0.26 10.6 0.0 2.2 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP VWA_2 PF13519.6 KDO27333.1 - 1.4e-05 25.7 0.0 6.4e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.19 KDO27333.1 - 5.7e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KDO27333.1 - 0.00024 19.4 0.0 0.00035 18.9 0.0 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KDO27333.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase VWA PF00092.28 KDO27333.1 - 0.097 12.9 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Linocin_M18 PF04454.12 KDO27333.1 - 0.15 11.3 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Encapsulating protein for peroxidase XendoU PF09412.10 KDO27335.1 - 1.7e-95 319.2 0.0 2.2e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU EGF_2 PF07974.13 KDO27335.1 - 5e-11 42.8 56.4 0.00012 22.3 8.6 6.0 6 0 0 6 6 6 4 EGF-like domain EndoU_bacteria PF14436.6 KDO27335.1 - 0.18 12.1 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial EndoU nuclease IQ PF00612.27 KDO27335.1 - 0.29 11.1 0.6 0.68 9.9 0.6 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif EGF PF00008.27 KDO27335.1 - 0.79 10.1 40.2 0.054 13.8 4.2 4.9 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 KDO27335.1 - 1 9.6 38.1 0.82 9.9 6.1 3.7 3 0 0 3 3 3 0 Laminin EGF domain DUF3043 PF11241.8 KDO27336.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pkinase_Tyr PF07714.17 KDO27337.1 - 4.5e-46 157.2 0.0 7.7e-46 156.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO27337.1 - 2.2e-42 145.3 0.0 2.8e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO27337.1 - 0.00072 18.4 0.0 0.00099 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO27337.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO27337.1 - 0.059 12.3 0.0 0.15 11.0 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Torus PF16131.5 KDO27338.1 - 4.3e-08 33.8 0.0 5.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KDO27338.1 - 3.3e-06 27.0 1.5 5.9e-06 26.1 1.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KDO27338.1 - 3.3e-05 23.7 2.5 5.7e-05 22.9 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO27338.1 - 0.0018 18.0 2.0 0.0033 17.2 2.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KDO27338.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger containing family LigB PF02900.18 KDO27339.1 - 1.8e-30 106.0 0.0 2.1e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LigB PF02900.18 KDO27340.1 - 2.3e-34 118.7 0.0 2.6e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase cNMP_binding PF00027.29 KDO27342.1 - 6.2e-27 93.5 0.0 2e-13 50.2 0.0 6.1 5 1 1 6 6 6 4 Cyclic nucleotide-binding domain Hydrolase_4 PF12146.8 KDO27343.1 - 1e-15 57.6 0.2 1.3e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 VWA PF00092.28 KDO27343.1 - 6.7e-09 36.2 0.0 4.5e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Abhydrolase_6 PF12697.7 KDO27343.1 - 2.4e-06 28.3 0.0 3.9e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family VWA_2 PF13519.6 KDO27343.1 - 8.6e-06 26.4 0.0 1.5e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Abhydrolase_1 PF00561.20 KDO27343.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KDO27343.1 - 0.001 18.9 0.1 0.015 15.1 0.1 2.4 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase VWA_3 PF13768.6 KDO27343.1 - 0.013 15.5 0.0 0.041 13.8 0.0 1.8 3 0 0 3 3 3 0 von Willebrand factor type A domain Peptidase_S15 PF02129.18 KDO27343.1 - 0.058 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 KDO27343.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF3342 PF11822.8 KDO27344.1 - 1.2e-26 92.7 0.1 2.1e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 KDO27344.1 - 0.0009 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5544 PF17698.1 KDO27344.1 - 0.09 12.9 3.8 0.2 11.7 3.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5544) PROL5-SMR PF15621.6 KDO27344.1 - 0.53 10.8 3.8 0.27 11.8 1.1 1.9 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Pkinase PF00069.25 KDO27345.1 - 1.9e-60 204.4 0.0 2.3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27345.1 - 1.7e-47 161.9 0.0 2.3e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27345.1 - 5.7e-07 29.1 0.1 2.5e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO27345.1 - 0.00069 18.5 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KDO27346.1 - 1.2e-56 192.0 0.0 1.7e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 KDO27346.1 - 4.4e-45 154.3 0.2 8.8e-45 153.3 0.2 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 KDO27346.1 - 1.3e-36 126.3 0.0 1.8e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27346.1 - 1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO27346.1 - 0.012 14.4 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KDO27346.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KDO27346.1 - 0.032 14.1 0.0 0.65 9.9 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf_PR_Knuckle PF18445.1 KDO27346.1 - 0.062 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 PR zinc knuckle motif WW PF00397.26 KDO27347.1 - 0.0001 22.3 0.7 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 WW domain HycA_repressor PF11046.8 KDO27347.1 - 0.11 12.6 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons ZZ PF00569.17 KDO27349.1 - 5.4e-10 38.9 2.8 1e-09 38.0 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-B_box PF00643.24 KDO27349.1 - 0.36 11.0 2.2 0.83 9.9 2.2 1.6 1 0 0 1 1 1 0 B-box zinc finger RabGAP-TBC PF00566.18 KDO27350.1 - 3.9e-10 39.7 0.3 6.9e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WW PF00397.26 KDO27350.1 - 1.6e-05 24.8 2.3 3.2e-05 23.9 2.3 1.5 1 0 0 1 1 1 1 WW domain Rhodanese PF00581.20 KDO27350.1 - 0.073 13.6 0.0 0.24 11.9 0.0 2.0 1 1 0 1 1 1 0 Rhodanese-like domain KAP PF05804.12 KDO27351.1 - 0.0013 17.0 0.0 0.0022 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) TBCA PF02970.16 KDO27351.1 - 6.3 7.2 8.0 30 5.0 3.8 2.9 2 0 0 2 2 2 0 Tubulin binding cofactor A PRCH PF03967.13 KDO27352.1 - 0.38 11.0 2.8 0.23 11.7 0.4 1.9 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region Dynein_C PF18199.1 KDO27353.1 - 5e-97 324.8 0.0 7.3e-97 324.3 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KDO27353.1 - 1.5e-89 298.9 0.4 2.8e-88 294.7 0.4 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 KDO27353.1 - 3e-48 163.7 0.2 7.6e-48 162.4 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO27353.1 - 4.5e-47 159.0 0.0 2.9e-43 146.7 0.0 2.4 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KDO27354.1 - 1.3e-160 533.8 0.0 2.2e-159 529.7 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO27354.1 - 1.1e-130 436.3 7.7 1.1e-130 436.3 7.7 2.6 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO27354.1 - 7e-103 343.5 0.9 6.2e-102 340.4 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KDO27354.1 - 8.5e-73 243.7 0.4 2e-68 229.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 KDO27354.1 - 2.2e-38 132.2 14.3 2.2e-38 132.2 14.3 1.9 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KDO27354.1 - 5.3e-21 75.1 0.6 3.8e-07 30.2 0.0 6.8 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KDO27354.1 - 4.1e-20 72.2 0.0 1.3e-19 70.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO27354.1 - 8e-20 70.9 0.0 3.1e-19 69.0 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KDO27354.1 - 7.6e-09 36.2 4.0 0.047 14.1 0.0 6.0 5 1 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 KDO27354.1 - 9.3e-09 35.7 0.0 0.092 13.0 0.0 5.4 6 0 0 6 6 4 2 AAA domain AAA PF00004.29 KDO27354.1 - 6.4e-08 33.1 0.0 0.17 12.3 0.0 5.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KDO27354.1 - 2.3e-06 27.9 0.2 4.6 7.7 0.0 4.6 4 0 0 4 4 3 2 RNA helicase NACHT PF05729.12 KDO27354.1 - 2.9e-05 24.1 0.1 0.13 12.2 0.0 3.7 3 0 0 3 3 3 1 NACHT domain T2SSE PF00437.20 KDO27354.1 - 4.3e-05 22.7 0.1 0.025 13.6 0.0 4.0 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_18 PF13238.6 KDO27354.1 - 7.8e-05 23.2 0.4 0.29 11.7 0.0 4.4 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 KDO27354.1 - 0.00044 20.0 0.6 0.047 13.4 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 KDO27354.1 - 0.0006 19.5 0.1 0.46 10.3 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain TsaE PF02367.17 KDO27354.1 - 0.0019 18.2 0.6 9.3 6.3 0.0 3.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KDO27354.1 - 0.0021 18.6 0.3 2.1 8.9 0.0 4.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 KDO27354.1 - 0.0027 17.1 0.8 1.3 8.3 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 KDO27354.1 - 0.0029 17.7 6.0 1.3 9.0 0.1 4.7 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_33 PF13671.6 KDO27354.1 - 0.0049 17.0 0.3 1.7 8.8 0.0 3.7 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 KDO27354.1 - 0.0089 15.2 0.3 2.4 7.3 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KDO27354.1 - 0.01 15.6 3.7 9.5 5.9 0.1 4.0 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 KDO27354.1 - 0.018 14.6 0.8 6.5 6.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO27354.1 - 0.02 14.3 0.5 12 5.2 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family Cytidylate_kin PF02224.18 KDO27354.1 - 0.027 14.2 0.0 7.9 6.1 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 KDO27354.1 - 0.042 13.1 1.0 6 6.1 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 KDO27354.1 - 0.078 13.3 2.7 90 3.4 0.1 5.0 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 KDO27354.1 - 0.11 12.7 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 KDO27354.1 - 0.17 10.7 4.5 1.6 7.6 0.0 3.2 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain Pacifastin_I PF05375.13 KDO27355.1 - 1.8 8.3 7.1 3.9 7.3 3.0 2.6 1 1 1 2 2 2 0 Pacifastin inhibitor (LCMII) VESA1_N PF12785.7 KDO27355.1 - 1.9 7.4 8.8 2.6 6.9 8.8 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Mto2_bdg PF12808.7 KDO27356.1 - 0.00079 19.7 0.3 0.0017 18.6 0.3 1.5 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region SIKE PF05769.11 KDO27356.1 - 0.068 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 SIKE family DUF4140 PF13600.6 KDO27356.1 - 0.14 12.6 0.6 0.29 11.6 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DGF-1_C PF11040.8 KDO27356.1 - 0.65 10.0 3.9 1.1 9.3 0.0 2.7 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TIP49 PF06068.13 KDO27357.1 - 9.9e-145 482.1 2.2 7.6e-135 449.6 0.2 2.2 1 1 1 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 KDO27357.1 - 3.1e-21 75.3 0.0 7.2e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA_22 PF13401.6 KDO27357.1 - 0.0026 18.0 0.0 0.0066 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_6 PF12774.7 KDO27358.1 - 1.2e-35 123.1 0.0 2.9e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO27358.1 - 1.5e-34 119.8 0.0 4.7e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KDO27358.1 - 7.9e-25 87.7 0.0 6.1e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KDO27358.1 - 5.1e-20 71.7 0.0 4e-17 62.3 0.0 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_8 PF12780.7 KDO27358.1 - 9.9e-16 57.8 0.0 3.5e-15 56.1 0.0 1.9 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO27358.1 - 1.4e-14 53.8 0.0 1.6e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 KDO27358.1 - 1e-13 51.4 1.7 9.1e-10 38.7 0.0 3.8 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KDO27358.1 - 7.9e-12 45.4 0.1 5.4e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KDO27358.1 - 1.3e-09 38.5 0.0 0.0038 17.6 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO27358.1 - 4.5e-09 36.9 11.1 0.079 13.3 0.1 6.9 5 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 KDO27358.1 - 1.6e-07 31.7 3.7 0.025 14.9 0.0 5.7 6 0 0 6 6 4 1 AAA domain AAA_5 PF07728.14 KDO27358.1 - 5.8e-06 26.4 0.1 2.8 8.0 0.0 5.1 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) HU-CCDC81_euk_2 PF18289.1 KDO27358.1 - 6.9e-06 26.1 0.5 0.00011 22.3 0.0 3.3 4 0 0 4 4 2 1 CCDC81 eukaryotic HU domain 2 AAA_33 PF13671.6 KDO27358.1 - 1.4e-05 25.3 2.8 8.7 6.5 0.0 6.6 7 0 0 7 7 6 0 AAA domain IstB_IS21 PF01695.17 KDO27358.1 - 4.5e-05 23.3 0.1 0.32 10.7 0.0 3.9 3 1 0 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 KDO27358.1 - 0.00011 21.9 0.4 0.26 11.0 0.0 4.1 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 KDO27358.1 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_28 PF13521.6 KDO27358.1 - 0.00014 22.1 0.6 9 6.5 0.0 4.8 4 0 0 4 4 4 0 AAA domain RuvB_N PF05496.12 KDO27358.1 - 0.00057 19.7 0.3 0.37 10.5 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KDO27358.1 - 0.0007 18.8 0.0 0.12 11.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_lid_11 PF18198.1 KDO27358.1 - 0.00085 19.2 0.0 0.12 12.2 0.0 2.8 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_18 PF13238.6 KDO27358.1 - 0.0042 17.6 0.0 17 5.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KDO27358.1 - 0.0063 17.0 1.0 60 4.1 0.0 4.5 5 0 0 5 5 4 0 ABC transporter Mg_chelatase PF01078.21 KDO27358.1 - 0.011 15.1 0.3 5.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KDO27358.1 - 0.011 14.8 0.3 5.9 5.9 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.6 KDO27358.1 - 0.011 15.4 0.0 7.6 6.2 0.0 3.6 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 KDO27358.1 - 0.019 15.4 0.1 36 4.8 0.0 3.9 4 0 0 4 4 3 0 RNA helicase AAA_11 PF13086.6 KDO27358.1 - 0.039 13.7 2.7 8.6 6.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 KDO27358.1 - 0.062 13.4 0.0 4 7.6 0.0 3.7 4 0 0 4 4 4 0 50S ribosome-binding GTPase TilS PF09179.11 KDO27358.1 - 0.086 13.4 5.0 3.9 8.0 0.2 4.8 3 0 0 3 3 2 0 TilS substrate binding domain Sigma54_activat PF00158.26 KDO27358.1 - 0.14 11.9 0.0 12 5.6 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KDO27358.1 - 0.37 11.1 3.1 15 5.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO27358.1 - 0.65 9.3 2.8 21 4.4 0.0 3.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family L27 PF02828.16 KDO27358.1 - 6 6.7 6.0 18 5.2 0.5 3.4 3 0 0 3 3 2 0 L27 domain Mog1 PF04603.12 KDO27359.1 - 2e-36 125.4 0.0 2.4e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Bax1-I PF01027.20 KDO27362.1 - 2.1e-32 112.6 28.1 2.6e-32 112.3 28.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FAD_binding_3 PF01494.19 KDO27364.1 - 8.8e-09 35.1 1.1 1.5e-08 34.3 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KDO27364.1 - 1.9e-06 27.7 0.0 1.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO27364.1 - 1.1e-05 25.6 0.1 2.9e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO27364.1 - 2.9e-05 23.5 0.0 3.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KDO27364.1 - 5e-05 22.6 0.3 8.2e-05 21.9 0.2 1.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KDO27364.1 - 0.00013 20.8 0.0 0.00014 20.7 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 KDO27364.1 - 0.00016 21.7 0.0 0.00023 21.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KDO27364.1 - 0.0002 20.7 0.1 0.00026 20.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO27364.1 - 0.00021 20.5 0.2 0.00031 19.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein ThiF PF00899.21 KDO27364.1 - 0.00031 20.2 0.2 0.00058 19.3 0.0 1.4 2 0 0 2 2 2 1 ThiF family Thi4 PF01946.17 KDO27364.1 - 0.00078 18.7 0.1 0.0011 18.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KDO27364.1 - 0.0011 18.9 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KDO27364.1 - 0.0028 18.2 0.0 0.0041 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KDO27364.1 - 0.003 17.8 0.0 0.0044 17.3 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 KDO27364.1 - 0.027 14.1 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KDO27364.1 - 0.071 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 KDO27364.1 - 0.21 10.7 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sugar_tr PF00083.24 KDO27365.1 - 7.2e-107 358.1 21.4 8.1e-107 357.9 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO27365.1 - 4.7e-29 101.4 31.4 1.1e-19 70.7 8.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO27365.1 - 0.00019 20.0 0.9 0.00031 19.3 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KDO27365.1 - 0.0069 15.0 3.5 0.0069 15.0 3.5 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein Ribonucleas_3_3 PF14622.6 KDO27366.1 - 1.1e-34 119.4 0.0 4.4e-17 62.5 0.0 2.8 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KDO27366.1 - 6.7e-33 113.5 0.4 6e-15 55.8 0.1 3.3 2 1 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 KDO27366.1 - 0.017 15.8 0.0 0.037 14.7 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif AlaDh_PNT_N PF05222.15 KDO27367.1 - 8.6e-29 100.6 0.0 1.4e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KDO27367.1 - 0.00019 20.8 0.0 0.0029 16.9 0.0 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RPEL PF02755.15 KDO27367.1 - 0.12 12.1 0.8 5.4 6.9 0.2 3.2 3 0 0 3 3 3 0 RPEL repeat Glucosamine_iso PF01182.20 KDO27369.1 - 1.9e-71 240.6 0.0 2.1e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RabGAP-TBC PF00566.18 KDO27370.1 - 6.2e-30 104.5 0.0 8.9e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 KDO27370.1 - 3.1e-05 23.8 0.4 6.7e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO27370.1 - 5e-05 23.0 0.2 0.00016 21.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain EMP70 PF02990.16 KDO27371.1 - 4.1e-155 517.4 16.6 4.1e-155 517.4 16.6 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 Aa_trans PF01490.18 KDO27372.1 - 5.2e-50 170.4 17.3 2.2e-49 168.3 17.3 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PalH PF08733.10 KDO27372.1 - 0.38 9.7 4.4 6.6 5.6 1.1 2.4 1 1 0 2 2 2 0 PalH/RIM21 Ras PF00071.22 KDO27373.1 - 6.2e-20 71.4 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO27373.1 - 1.3e-14 54.5 0.0 2.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH2 PF00017.24 KDO27373.1 - 2.3e-06 27.6 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Arf PF00025.21 KDO27373.1 - 0.00014 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KDO27373.1 - 0.069 13.5 0.0 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KDO27373.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DnaJ PF00226.31 KDO27374.1 - 7.5e-27 93.2 1.6 1.1e-26 92.8 0.9 1.6 2 0 0 2 2 2 1 DnaJ domain Coatomer_E PF04733.14 KDO27375.1 - 3.3e-75 253.2 0.3 3.7e-75 253.0 0.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.28 KDO27375.1 - 0.00073 19.3 1.0 0.54 10.2 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27375.1 - 0.001 19.5 11.0 0.02 15.4 0.3 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27375.1 - 0.0014 18.5 7.3 0.0073 16.3 0.1 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27375.1 - 0.0088 16.8 2.2 0.85 10.6 0.0 4.3 2 2 3 5 5 5 1 Tetratricopeptide repeat MRP-S28 PF10213.9 KDO27376.1 - 7.1e-14 52.3 0.3 1.3e-13 51.4 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein F-box-like PF12937.7 KDO27377.1 - 0.00031 20.6 0.0 0.0008 19.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like ACT_5 PF13710.6 KDO27379.1 - 0.076 12.9 0.6 0.19 11.6 0.6 1.7 1 0 0 1 1 1 0 ACT domain Ferric_reduct PF01794.19 KDO27380.1 - 2e-15 57.0 6.8 2e-15 57.0 6.8 2.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO27380.1 - 1.1e-10 41.8 0.0 3.1e-10 40.4 0.0 1.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO27380.1 - 1.9e-07 31.2 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KDO27380.1 - 0.013 16.1 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KDO27380.1 - 0.049 14.0 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Histone_H2A_C PF16211.5 KDO27381.1 - 2.9e-18 65.3 3.5 6.4e-18 64.2 3.5 1.7 1 1 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KDO27381.1 - 7.4e-16 58.7 0.0 9.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KDO27381.1 - 0.00014 22.1 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO27382.1 - 5e-20 72.2 0.2 6.2e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KDO27382.1 - 0.00021 21.7 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KDO27382.1 - 0.0014 18.9 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KDO27382.1 - 0.0021 18.1 0.1 0.0025 17.9 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Steroid_dh PF02544.16 KDO27383.1 - 6.8e-48 162.5 0.3 1.6e-47 161.3 0.3 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KDO27383.1 - 7.7e-06 25.6 0.3 7.7e-06 25.6 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) CorA PF01544.18 KDO27384.1 - 3e-53 181.1 4.0 1.5e-45 155.8 1.5 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein CENP-T_C PF15511.6 KDO27385.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO27385.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO27385.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO27385.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO27385.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO27385.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO27385.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KDO27386.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KDO27386.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO27386.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO27386.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KDO27386.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO27386.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit LSM14 PF12701.7 KDO27393.1 - 2.4e-28 98.0 0.0 4.1e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KDO27393.1 - 6.2e-06 27.0 5.1 0.0002 22.2 0.0 2.9 2 1 1 3 3 3 2 FDF domain SM-ATX PF14438.6 KDO27393.1 - 0.00038 20.5 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain MFAP1 PF06991.11 KDO27394.1 - 2.1e-64 217.4 35.1 2.1e-64 217.4 35.1 1.7 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Acyl-CoA_dh_1 PF00441.24 KDO27395.1 - 9e-48 162.3 1.8 1.5e-47 161.5 1.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KDO27395.1 - 1.6e-26 93.2 0.2 4.3e-26 91.8 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KDO27395.1 - 1.8e-23 82.5 0.2 3.6e-23 81.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KDO27395.1 - 9.8e-20 71.2 0.2 1.8e-19 70.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KDO27395.1 - 0.0014 18.4 0.0 0.0046 16.7 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DEAD PF00270.29 KDO27396.1 - 3.4e-37 127.9 0.1 7.2e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO27396.1 - 3.8e-26 91.6 0.1 4.4e-24 85.0 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO27396.1 - 1.5e-06 28.3 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KDO27396.1 - 0.0002 20.8 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit WAPL PF07814.13 KDO27397.1 - 1.3e-12 47.2 4.6 3.7e-11 42.4 4.6 2.7 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin EF-hand_6 PF13405.6 KDO27398.1 - 1.9e-28 95.9 0.8 0.071 13.1 0.0 10.1 9 1 1 10 10 10 9 EF-hand domain EF-hand_7 PF13499.6 KDO27398.1 - 1.5e-27 95.8 0.0 0.00018 21.8 0.0 7.1 6 1 2 8 8 8 7 EF-hand domain pair EF-hand_1 PF00036.32 KDO27398.1 - 5e-25 85.2 0.0 0.027 14.0 0.1 8.4 8 0 0 8 8 8 7 EF hand EF-hand_8 PF13833.6 KDO27398.1 - 1.3e-17 63.4 5.5 0.086 12.7 0.1 8.4 6 2 2 8 8 8 5 EF-hand domain pair EF-hand_5 PF13202.6 KDO27398.1 - 3e-14 51.8 6.3 0.16 11.5 0.3 8.1 8 0 0 8 8 8 3 EF hand Dzip-like_N PF13815.6 KDO27398.1 - 1.2e-05 25.2 0.5 1.2e-05 25.2 0.5 2.6 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal EF-hand_9 PF14658.6 KDO27398.1 - 0.1 12.9 2.7 3.8 7.9 0.0 4.6 6 0 0 6 6 6 0 EF-hand domain KIAA1430 PF13879.6 KDO27398.1 - 0.56 11.0 4.7 0.094 13.5 0.8 1.7 2 0 0 2 2 2 0 KIAA1430 homologue Acyl-CoA_dh_1 PF00441.24 KDO27399.1 - 1.2e-49 168.4 3.2 2.2e-49 167.5 3.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KDO27399.1 - 2.9e-26 91.5 0.4 7.1e-26 90.3 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KDO27399.1 - 1.6e-23 83.5 0.1 4.8e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KDO27399.1 - 5.4e-20 72.0 0.4 1.1e-19 71.0 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KDO27399.1 - 4.3e-05 23.3 0.7 0.00028 20.6 0.7 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Fe-ADH PF00465.19 KDO27400.1 - 1.8e-55 188.2 0.3 2.3e-55 187.9 0.3 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KDO27400.1 - 2.8e-10 40.3 1.2 8.9e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AAA_31 PF13614.6 KDO27402.1 - 3e-18 66.4 0.6 5.7e-15 55.7 0.6 2.2 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KDO27402.1 - 5e-18 65.4 0.0 6.8e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KDO27402.1 - 9.6e-16 58.0 2.0 3e-14 53.1 2.0 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 KDO27402.1 - 4.9e-11 42.4 0.1 1.2e-10 41.2 0.0 1.5 1 1 1 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 KDO27402.1 - 4.6e-10 39.4 0.2 2.7e-07 30.3 0.2 2.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KDO27402.1 - 1.6e-08 34.1 0.9 1.6e-08 34.1 0.9 1.9 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_24 PF13479.6 KDO27402.1 - 0.00028 20.7 0.1 0.00042 20.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KDO27402.1 - 0.0018 17.8 0.4 0.4 10.1 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KDO27402.1 - 0.0022 17.8 2.7 0.76 9.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 KDO27402.1 - 0.0024 17.5 0.1 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 KDO27402.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 KaiC CLP1_P PF16575.5 KDO27402.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 KDO27402.1 - 0.069 12.4 0.2 0.086 12.1 0.2 1.4 1 1 0 1 1 1 0 VirC1 protein Kelch_4 PF13418.6 KDO27403.1 - 4.4e-47 157.9 1.9 4.7e-13 48.9 0.0 7.4 5 2 2 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KDO27403.1 - 7.9e-39 131.3 0.8 6.5e-11 42.2 0.0 7.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO27403.1 - 1.1e-35 120.7 0.3 1.6e-09 37.7 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KDO27403.1 - 7.9e-28 96.0 0.4 1.2e-05 25.2 0.0 6.7 6 1 0 6 6 6 6 Kelch motif DUF4110 PF13422.6 KDO27403.1 - 4.2e-26 90.9 1.4 4.2e-26 90.9 1.4 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 KDO27403.1 - 2.8e-24 84.4 2.1 0.00024 20.6 0.1 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KDO27403.1 - 6.5e-21 73.5 7.1 0.00098 19.0 0.0 7.0 6 2 0 6 6 6 5 Kelch motif Rop PF01815.16 KDO27403.1 - 0.039 13.8 0.0 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Rop protein CBP_BcsG PF11658.8 KDO27403.1 - 0.15 10.5 1.2 0.33 9.3 1.2 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG RsbRD_N PF14361.6 KDO27403.1 - 0.34 11.6 2.7 0.33 11.7 0.3 2.2 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF1451 PF07295.11 KDO27403.1 - 0.81 9.7 7.5 8.1 6.5 1.1 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Membralin PF09746.9 KDO27404.1 - 4.6e-12 45.7 16.1 4.6e-10 39.1 11.3 2.2 1 1 1 2 2 2 2 Tumour-associated protein WD40 PF00400.32 KDO27406.1 - 1.4e-15 57.4 12.4 2.3e-05 25.1 0.1 10.0 10 0 0 10 10 10 5 WD domain, G-beta repeat ProRS-C_1 PF09180.11 KDO27408.1 - 2.7e-22 78.7 0.5 5.8e-22 77.7 0.5 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KDO27408.1 - 1.3e-17 63.7 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KDO27408.1 - 3.6e-17 62.9 0.0 5.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) EF-G-binding_N PF07299.11 KDO27408.1 - 0.045 14.3 1.1 2.3 8.8 0.5 2.3 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal adh_short PF00106.25 KDO27409.1 - 5.3e-32 110.9 0.1 4.5e-31 107.8 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO27409.1 - 1.8e-19 70.2 0.2 2.7e-19 69.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO27409.1 - 2.2e-09 37.5 0.1 3.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO27409.1 - 2.9e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KDO27409.1 - 0.0035 17.2 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 KDO27409.1 - 0.0092 15.1 0.1 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KDO27409.1 - 0.044 13.8 0.1 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KDO27409.1 - 0.057 13.3 0.2 0.091 12.6 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KDO27409.1 - 0.058 12.7 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KDO27409.1 - 0.17 12.2 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ctf8 PF09696.10 KDO27410.1 - 2.7e-10 40.7 2.0 0.00026 21.3 0.0 3.0 1 1 2 3 3 3 3 Ctf8 Ank_4 PF13637.6 KDO27411.1 - 0.048 14.3 0.1 0.16 12.6 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sugar_tr PF00083.24 KDO27412.1 - 1e-104 350.9 24.1 1.2e-104 350.7 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO27412.1 - 2.1e-32 112.4 28.9 7.7e-23 81.0 8.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM100 PF16311.5 KDO27412.1 - 2.4 7.7 4.5 0.78 9.3 0.7 2.1 2 0 0 2 2 2 0 Transmembrane protein 100 NPR3 PF03666.13 KDO27413.1 - 2.7e-43 148.5 8.7 2.4e-21 76.1 3.9 3.1 1 1 2 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KDO27413.1 - 0.0014 17.5 0.1 0.012 14.4 0.0 2.1 2 1 0 2 2 2 1 Nitrogen permease regulator 2 Rap_GAP PF02145.15 KDO27414.1 - 2.4e-06 27.3 0.0 8.4e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Rap/ran-GAP zf-C3HC4_2 PF13923.6 KDO27415.1 - 3.2e-10 39.7 7.0 3.2e-10 39.7 7.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO27415.1 - 1.2e-09 37.9 7.5 1.2e-09 37.9 7.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO27415.1 - 3.1e-09 37.0 6.6 3.1e-09 37.0 6.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO27415.1 - 1.8e-08 34.1 5.1 1.8e-08 34.1 5.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO27415.1 - 3.9e-08 33.2 8.1 9.1e-08 32.0 8.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO27415.1 - 3.1e-07 30.3 7.6 3.1e-07 30.3 7.6 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KDO27415.1 - 8.5e-07 29.0 6.3 2.2e-06 27.7 6.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KDO27415.1 - 5e-05 23.1 12.5 0.00012 21.8 10.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO27415.1 - 0.00035 20.8 8.5 0.0015 18.8 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KDO27415.1 - 0.0045 16.8 2.2 0.0086 15.9 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KDO27415.1 - 0.011 15.5 9.5 0.06 13.1 6.9 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KDO27415.1 - 0.037 13.9 0.3 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KDO27415.1 - 0.054 13.3 5.4 0.054 13.3 5.4 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 KDO27415.1 - 0.064 13.1 7.2 0.051 13.5 5.5 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KDO27415.1 - 0.18 11.5 3.9 0.32 10.7 3.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 KDO27415.1 - 1.1 9.5 7.7 0.47 10.6 4.7 1.8 1 1 1 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 KDO27415.1 - 3.2 7.8 10.6 0.95 9.5 5.4 2.1 1 1 1 2 2 2 0 zinc-ribbons FYVE PF01363.21 KDO27415.1 - 3.5 7.8 8.6 2.1 8.6 5.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger FA_desaturase PF00487.24 KDO27416.1 - 1.6e-14 54.4 11.5 2.2e-14 53.9 11.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DNA_repr_REX1B PF14966.6 KDO27417.1 - 1.8e-20 73.4 1.4 3.4e-20 72.5 1.4 1.5 1 0 0 1 1 1 1 DNA repair REX1-B DUF1192 PF06698.11 KDO27417.1 - 0.052 13.6 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF2939 PF11159.8 KDO27417.1 - 0.07 13.5 0.3 0.14 12.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) zf-U1 PF06220.12 KDO27418.1 - 7.7e-05 22.4 0.2 9.4e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 U1 zinc finger ASH PF15780.5 KDO27419.1 - 1.9e-12 47.2 8.3 0.015 15.5 0.2 10.4 12 0 0 12 12 12 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KDO27419.1 - 0.0015 18.7 0.8 0.59 10.4 0.1 4.1 3 1 0 3 3 3 1 Transmembrane protein 131-like FixG_C PF11614.8 KDO27419.1 - 0.041 14.1 1.9 3.1 8.1 0.1 5.2 7 0 0 7 7 7 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Abhydrolase_6 PF12697.7 KDO27420.1 - 1.1e-08 36.0 0.7 4.3e-08 34.0 0.1 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO27420.1 - 2.6e-05 23.6 0.0 5.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF818 PF05677.12 KDO27420.1 - 7.7e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.20 KDO27420.1 - 0.00048 19.9 0.1 0.00088 19.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO27420.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pox_VERT_large PF04441.13 KDO27421.1 - 0.31 9.2 0.3 0.4 8.9 0.3 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit Tudor-knot PF11717.8 KDO27422.1 - 0.021 14.7 0.4 0.052 13.4 0.4 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain GlcNAc PF11397.8 KDO27423.1 - 3.4e-22 79.4 1.3 7.3e-20 71.7 1.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) DivIC PF04977.15 KDO27424.1 - 0.019 14.8 0.6 0.019 14.8 0.6 8.7 3 3 3 8 8 8 0 Septum formation initiator HALZ PF02183.18 KDO27424.1 - 0.31 11.3 0.1 0.31 11.3 0.1 6.8 7 0 0 7 7 7 0 Homeobox associated leucine zipper Trep_dent_lipo PF09710.10 KDO27424.1 - 1.5 7.6 4.2 3.4 6.5 4.2 1.5 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) DUF3584 PF12128.8 KDO27424.1 - 2.9 5.3 64.3 0.9 7.0 18.3 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3584) CCDC92 PF14916.6 KDO27424.1 - 4 7.3 10.5 1.8 8.4 0.3 4.6 5 0 0 5 5 5 0 Coiled-coil domain of unknown function HOOK PF05622.12 KDO27424.1 - 5.1 5.1 60.6 0.44 8.6 28.5 3.0 2 1 0 2 2 2 0 HOOK protein Noelin-1 PF12308.8 KDO27424.1 - 9.7 6.2 15.5 0.44 10.6 0.1 4.9 3 1 3 6 6 6 0 Neurogenesis glycoprotein EI24 PF07264.11 KDO27425.1 - 4.8e-34 118.1 14.9 6e-34 117.8 14.9 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TPR_9 PF13371.6 KDO27426.1 - 6.9e-08 32.5 0.8 6.9e-08 32.5 0.8 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO27426.1 - 2.5e-06 27.1 1.3 0.14 12.0 0.8 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27426.1 - 5.5e-06 26.1 7.2 0.15 12.3 1.9 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27426.1 - 0.07 13.7 0.3 0.07 13.7 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO27426.1 - 0.078 12.7 0.4 0.51 10.1 0.5 2.2 2 0 0 2 2 2 0 TPR repeat Fis1_TPR_C PF14853.6 KDO27426.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KDO27426.1 - 0.13 13.2 9.1 5.9 8.0 0.6 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KDO27426.1 - 0.97 9.1 6.7 0.19 11.4 0.9 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain EF-hand_8 PF13833.6 KDO27427.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO27427.1 - 0.031 14.7 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KDO27427.1 - 0.036 14.0 0.0 15 5.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 KDO27427.1 - 0.055 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain LNS2 PF08235.13 KDO27429.1 - 3.9e-47 160.6 0.0 5.7e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KDO27429.1 - 1.8e-09 37.5 0.0 1.4e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 lipin, N-terminal conserved region Malate_synthase PF01274.22 KDO27430.1 - 6.2e-207 688.0 0.0 7.1e-207 687.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KDO27430.1 - 0.0046 16.1 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AAA_12 PF13087.6 KDO27432.1 - 2.3e-34 118.8 0.0 3.9e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KDO27432.1 - 1.1e-23 84.4 0.0 3.5e-23 82.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO27432.1 - 6.8e-12 45.9 0.0 1e-10 42.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO27432.1 - 3.1e-08 33.6 0.0 0.0011 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KDO27432.1 - 2.1e-07 30.5 0.0 2.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KDO27432.1 - 0.0015 18.1 0.0 0.0098 15.4 0.0 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KDO27432.1 - 0.015 15.5 0.1 0.068 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 KDO27432.1 - 0.025 14.4 0.1 0.098 12.5 0.0 2.1 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KDO27432.1 - 0.068 13.6 0.1 0.65 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 KDO27432.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Med19 PF10278.9 KDO27432.1 - 4 7.3 5.8 7.6 6.4 5.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Copine PF07002.16 KDO27433.1 - 1.7e-65 220.5 0.0 2.1e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 KDO27433.1 - 2.4e-09 37.6 0.1 3.3e-09 37.1 0.1 1.3 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KDO27433.1 - 0.026 14.8 0.1 0.052 13.8 0.1 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA_3 PF13768.6 KDO27433.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 von Willebrand factor type A domain COPIIcoated_ERV PF07970.12 KDO27434.1 - 3.5e-66 223.2 0.3 4.8e-66 222.8 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KDO27434.1 - 2.4e-25 88.7 0.3 4.4e-25 87.8 0.3 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1282 PF06930.12 KDO27434.1 - 0.04 13.7 1.0 1.3 8.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) WW PF00397.26 KDO27435.1 - 2.9e-07 30.5 0.6 5.2e-07 29.6 0.6 1.4 1 0 0 1 1 1 1 WW domain Copine PF07002.16 KDO27436.1 - 1.4e-64 217.5 0.0 2.6e-64 216.7 0.0 1.4 2 0 0 2 2 2 1 Copine vWA-TerF-like PF10138.9 KDO27436.1 - 2.4e-10 40.8 0.0 3.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KDO27436.1 - 0.002 18.4 0.0 0.0038 17.5 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 KDO27437.1 - 1.3e-64 217.6 0.0 3.7e-64 216.2 0.0 1.6 2 0 0 2 2 2 1 Copine vWA-TerF-like PF10138.9 KDO27437.1 - 5.9e-11 42.9 0.0 8.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 KDO27437.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Copine PF07002.16 KDO27438.1 - 1.5e-64 217.4 0.0 1.8e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 KDO27438.1 - 5.6e-12 46.2 0.0 6.7e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KDO27438.1 - 0.00059 20.1 0.0 0.00082 19.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KDO27438.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Copine PF07002.16 KDO27439.1 - 1.5e-56 191.3 0.0 1.8e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 KDO27439.1 - 1.4e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus FA_hydroxylase PF04116.13 KDO27440.1 - 6.6e-30 104.2 12.4 6.6e-30 104.2 12.4 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Mob_synth_C PF06463.13 KDO27441.1 - 5.4e-39 133.0 0.0 8.8e-39 132.4 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KDO27441.1 - 2.9e-26 92.8 0.0 4.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KDO27441.1 - 2e-07 31.4 0.0 7.2e-07 29.6 0.0 1.9 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KDO27441.1 - 0.00093 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain RRM_1 PF00076.22 KDO27442.1 - 1.5e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_2 PF00328.22 KDO27443.1 - 8.1e-05 22.1 0.9 0.26 10.6 0.7 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF1084 PF06454.11 KDO27444.1 - 5.4e-37 127.6 6.9 8.4e-37 127.0 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Tmemb_185A PF10269.9 KDO27444.1 - 0.032 13.9 0.2 0.032 13.9 0.2 1.9 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein GTP_cyclohydroI PF01227.22 KDO27445.1 - 4.6e-74 247.7 0.4 5.9e-74 247.4 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I Aminotran_1_2 PF00155.21 KDO27445.1 - 0.028 13.6 0.1 0.054 12.7 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II Syntaxin PF00804.25 KDO27445.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Syntaxin Methyltr_RsmB-F PF01189.17 KDO27446.1 - 5.8e-39 133.8 0.0 3.2e-37 128.1 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 KDO27446.1 - 3.6e-06 26.8 0.1 1.4e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 PUA domain FtsJ PF01728.19 KDO27446.1 - 3.7e-06 27.2 0.0 1.3e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KDO27446.1 - 0.0089 15.4 0.0 0.074 12.4 0.0 2.3 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KDO27446.1 - 0.0099 15.7 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KDO27446.1 - 0.065 13.9 0.0 0.35 11.6 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 KDO27446.1 - 0.072 12.9 0.0 1.3 8.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 KDO27446.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin UQ_con PF00179.26 KDO27448.1 - 1.8e-18 66.5 0.0 2.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L6e PF01159.19 KDO27449.1 - 9.2e-39 132.4 2.2 9.2e-39 132.4 2.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e 6PF2K PF01591.18 KDO27450.1 - 8e-63 211.7 0.0 1.1e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KDO27450.1 - 9e-24 84.2 0.0 2.8e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KDO27450.1 - 0.00063 19.9 0.1 0.002 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF2313 PF10076.9 KDO27450.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) Kinesin PF00225.23 KDO27451.1 - 1.1e-51 175.7 0.0 1.5e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO27451.1 - 9.6e-18 64.5 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding Metallophos PF00149.28 KDO27452.1 - 6.5e-37 128.0 0.2 8.3e-37 127.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KDO27452.1 - 6.1e-05 23.4 0.2 0.00013 22.4 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KDO27452.1 - 0.039 14.1 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DHC_N1 PF08385.12 KDO27453.1 - 3.5e-31 108.5 0.0 4.4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Corona_3 PF04694.12 KDO27454.1 - 0.16 12.3 0.0 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Coronavirus ORF3 protein zf-CXXC PF02008.20 KDO27455.1 - 2.3e-17 62.7 45.3 1.5e-10 40.9 18.0 3.7 5 0 0 5 5 5 2 CXXC zinc finger domain FHA PF00498.26 KDO27455.1 - 0.0017 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain SNF2_N PF00176.23 KDO27455.1 - 0.0052 15.5 0.2 0.0095 14.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C2H2_4 PF13894.6 KDO27455.1 - 0.02 15.7 1.4 0.02 15.7 1.4 5.3 6 0 0 6 6 6 0 C2H2-type zinc finger RPN2_C PF18004.1 KDO27455.1 - 0.1 12.5 1.1 0.2 11.5 1.1 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain zf-C2H2_jaz PF12171.8 KDO27455.1 - 0.13 12.6 2.1 0.4 11.0 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KDO27455.1 - 2.6 8.6 7.7 12 6.5 0.3 4.0 3 0 0 3 3 3 0 Zinc-finger double domain PsaL PF02605.15 KDO27456.1 - 0.00061 19.5 0.0 0.0007 19.3 0.0 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Gram_pos_anchor PF00746.21 KDO27456.1 - 0.2 11.6 1.4 0.32 11.0 1.4 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LNS2 PF08235.13 KDO27457.1 - 1.9e-45 155.1 0.0 2.6e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KDO27457.1 - 4.9e-07 29.6 0.0 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Trs65 PF12735.7 KDO27458.1 - 2.3e-05 24.0 0.1 0.038 13.4 0.0 2.7 1 1 1 3 3 3 2 TRAPP trafficking subunit Trs65 PX PF00787.24 KDO27459.1 - 1.5e-06 28.2 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF2196 PF09962.9 KDO27460.1 - 1.1e-24 86.1 2.2 1.6e-24 85.7 2.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-RanBP PF00641.18 KDO27460.1 - 8.2e-05 21.8 1.3 0.00014 21.1 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FAM176 PF14851.6 KDO27461.1 - 0.019 14.6 0.1 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Pam17 PF08566.10 KDO27461.1 - 0.26 11.1 1.1 0.73 9.7 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Rav1p_C PF12234.8 KDO27462.1 - 7.6e-44 150.2 0.3 1.4e-43 149.3 0.3 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal C2 PF00168.30 KDO27462.1 - 0.0016 18.7 0.0 2.1 8.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain DEP PF00610.21 KDO27462.1 - 0.0092 16.0 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DNA_pol_B_palm PF14792.6 KDO27464.1 - 3.1e-30 104.7 0.1 7.4e-30 103.5 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KDO27464.1 - 3.7e-18 65.1 0.0 7.4e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KDO27464.1 - 4e-16 58.9 0.0 1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KDO27464.1 - 1.9e-07 31.3 0.1 8.2e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KDO27464.1 - 0.00011 22.7 0.0 0.00048 20.7 0.0 2.2 2 1 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KDO27464.1 - 0.028 14.6 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus FYVE PF01363.21 KDO27465.1 - 8.4e-15 54.7 10.2 1.5e-14 53.9 10.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUSP PF06337.12 KDO27465.1 - 1.8e-12 47.7 0.0 2.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 DUSP domain FYVE_2 PF02318.16 KDO27465.1 - 0.084 13.1 10.9 0.11 12.7 9.8 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 KDO27465.1 - 5 7.1 14.9 1.2 9.1 9.0 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4205 PF13898.6 KDO27466.1 - 2.2e-47 161.7 0.0 8e-46 156.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) EF-hand_7 PF13499.6 KDO27466.1 - 0.096 13.2 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Leu_zip PF15294.6 KDO27467.1 - 1e-27 97.4 20.9 1.8e-22 80.2 10.7 2.1 1 1 1 2 2 2 2 Leucine zipper DUF4515 PF14988.6 KDO27467.1 - 0.0017 18.3 7.5 0.0017 18.3 7.5 2.3 1 1 0 2 2 2 1 Domain of unknown function (DUF4515) TolA_bind_tri PF16331.5 KDO27467.1 - 0.0061 16.6 13.5 0.0081 16.2 4.1 3.2 2 1 0 2 2 2 1 TolA binding protein trimerisation KASH_CCD PF14662.6 KDO27467.1 - 0.012 15.5 15.0 0.041 13.7 14.9 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PKcGMP_CC PF16808.5 KDO27467.1 - 0.014 15.2 2.8 0.014 15.2 2.8 2.5 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KDO27467.1 - 0.025 13.5 12.0 0.059 12.3 12.0 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein KLRAQ PF10205.9 KDO27467.1 - 0.025 14.8 3.3 0.025 14.8 3.3 3.0 3 1 2 5 5 5 0 Predicted coiled-coil domain-containing protein PHM7_cyt PF14703.6 KDO27467.1 - 0.068 13.4 4.0 0.089 13.0 2.8 1.8 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter bZIP_1 PF00170.21 KDO27467.1 - 0.092 12.9 0.2 0.092 12.9 0.2 3.0 3 0 0 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 KDO27467.1 - 0.11 12.4 2.2 1.5 8.7 0.3 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 KDO27467.1 - 0.18 11.2 14.7 0.11 11.8 12.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 KDO27467.1 - 0.18 11.9 0.4 0.18 11.9 0.4 3.3 3 0 0 3 3 3 0 Basic region leucine zipper Uds1 PF15456.6 KDO27467.1 - 0.25 11.5 11.9 1.2 9.3 11.9 2.1 1 1 0 1 1 1 0 Up-regulated During Septation TPR_MLP1_2 PF07926.12 KDO27467.1 - 0.96 9.5 18.7 0.075 13.1 12.8 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 KDO27467.1 - 1.3 9.7 13.7 2.6 8.7 0.9 4.0 1 1 2 3 3 3 0 SlyX NYD-SP28 PF14772.6 KDO27467.1 - 1.3 9.1 17.6 1.5 8.9 2.8 3.8 1 1 2 4 4 4 0 Sperm tail Phage_GPO PF05929.11 KDO27467.1 - 3.4 7.2 14.0 0.38 10.3 4.4 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Swi5 PF07061.11 KDO27467.1 - 3.9 7.6 7.9 7.1 6.8 2.6 3.4 1 1 2 3 3 3 0 Swi5 RPA_interact_M PF14767.6 KDO27467.1 - 5.4 7.7 14.8 0.58 10.8 7.3 2.7 2 1 0 2 2 2 0 Replication protein A interacting middle YabA PF06156.13 KDO27467.1 - 6.3 7.5 10.8 23 5.7 7.3 3.2 1 1 1 2 2 2 0 Initiation control protein YabA Syntaxin_2 PF14523.6 KDO27467.1 - 8.4 6.8 10.1 43 4.6 8.4 2.7 1 1 1 2 2 2 0 Syntaxin-like protein DUF5543 PF17697.1 KDO27468.1 - 0.044 14.1 0.7 0.63 10.3 0.2 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5543) FbpA PF05833.11 KDO27470.1 - 4e-34 118.2 2.9 7e-34 117.4 2.9 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KDO27470.1 - 3.5e-32 111.3 0.0 1.5e-31 109.3 0.0 2.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KDO27470.1 - 1e-30 105.7 0.0 1e-30 105.7 0.0 3.1 3 0 0 3 3 3 1 NFACT protein C-terminal domain DUF5590 PF17881.1 KDO27470.1 - 0.042 13.9 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) Adeno_E3 PF06040.11 KDO27470.1 - 0.17 12.0 0.0 0.54 10.4 0.0 1.8 1 0 0 1 1 1 0 Adenovirus E3 protein Phycobilisome PF00502.19 KDO27470.1 - 0.63 10.0 5.1 0.13 12.2 1.1 1.9 2 0 0 2 2 2 0 Phycobilisome protein OTU PF02338.19 KDO27471.1 - 1.6e-22 80.3 0.0 1.6e-22 80.3 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KDO27471.1 - 4e-05 23.2 1.4 0.0048 16.4 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain Golgin_A5 PF09787.9 KDO27471.1 - 0.28 10.6 14.5 0.061 12.8 6.5 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KDO27471.1 - 8.1 6.6 21.6 7.3 6.8 10.2 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DnaJ PF00226.31 KDO27472.1 - 1.9e-16 59.9 0.3 6.7e-16 58.2 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Lipase_3 PF01764.25 KDO27472.1 - 0.0015 18.4 0.1 0.14 12.0 0.0 2.8 3 0 0 3 3 3 2 Lipase (class 3) Fis1_TPR_C PF14853.6 KDO27473.1 - 0.0081 16.2 0.4 0.013 15.6 0.4 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 KDO27473.1 - 0.014 15.2 12.7 0.016 15.0 12.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M16_C PF05193.21 KDO27473.1 - 0.03 14.4 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase M16 inactive domain RXT2_N PF08595.11 KDO27473.1 - 0.13 12.3 6.7 0.16 12.0 6.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Wzy_C_2 PF11846.8 KDO27473.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Sporozoite_P67 PF05642.11 KDO27473.1 - 0.25 9.4 6.4 0.31 9.1 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.11 KDO27473.1 - 0.3 10.6 8.4 0.34 10.5 8.4 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KDO27473.1 - 0.36 10.1 13.1 0.41 9.9 13.1 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KDO27473.1 - 1.6 6.9 8.4 1.7 6.9 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KDO27473.1 - 2.3 6.2 17.3 2.7 6.0 17.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KDO27473.1 - 3 5.9 14.5 3.5 5.7 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KDO27473.1 - 3.5 6.0 11.3 4.3 5.8 11.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 KDO27473.1 - 3.6 8.0 22.1 7.5 7.0 22.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Dicty_REP PF05086.12 KDO27473.1 - 4.9 5.0 6.8 5.2 4.9 6.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2457 PF10446.9 KDO27473.1 - 7.6 5.6 18.7 8.5 5.4 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TPR_1 PF00515.28 KDO27474.1 - 3.1e-13 48.9 12.7 0.0083 15.9 0.0 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27474.1 - 5.3e-13 48.0 15.4 0.032 14.3 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27474.1 - 1.2e-10 41.5 19.0 0.00017 21.8 3.7 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27474.1 - 1.4e-08 34.8 16.3 0.0038 17.9 0.2 8.8 7 1 2 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27474.1 - 0.00015 22.2 22.1 0.97 10.0 0.7 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO27474.1 - 0.0048 17.0 14.7 0.83 10.0 0.5 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO27474.1 - 0.025 15.2 27.2 0.38 11.5 0.2 6.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO27474.1 - 0.044 14.2 0.5 4.9 7.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO27474.1 - 0.05 13.8 5.5 4.2 7.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 KDO27474.1 - 0.057 13.8 0.0 0.41 11.1 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats MAS20 PF02064.15 KDO27474.1 - 0.098 12.8 0.4 7 6.8 0.1 2.9 2 1 0 2 2 2 0 MAS20 protein import receptor TPR_10 PF13374.6 KDO27474.1 - 0.099 12.5 7.4 9.8 6.2 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_M9_N PF08453.10 KDO27474.1 - 0.18 11.5 0.8 3.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Peptidase family M9 N-terminal CDC37_N PF03234.14 KDO27474.1 - 6.4 7.7 11.6 0.16 12.8 1.9 3.2 4 0 0 4 4 4 0 Cdc37 N terminal kinase binding Glutaminase PF04960.15 KDO27475.1 - 6.4e-181 599.8 0.0 2.1e-109 365.1 0.0 2.2 2 0 0 2 2 2 2 Glutaminase Ank_2 PF12796.7 KDO27475.1 - 8e-33 112.9 0.4 3.4e-10 40.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27475.1 - 1.3e-28 99.0 1.3 9e-09 35.7 0.1 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) EF-hand_14 PF17959.1 KDO27475.1 - 6.1e-20 71.4 0.0 8.8e-09 35.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain Ank_5 PF13857.6 KDO27475.1 - 1.3e-19 70.0 0.8 3.4e-06 27.2 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO27475.1 - 1.9e-19 69.2 4.9 0.00015 22.0 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 KDO27475.1 - 4.3e-19 66.6 0.8 0.004 17.5 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat EF-hand_6 PF13405.6 KDO27475.1 - 0.017 15.0 0.7 0.082 12.9 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KDO27475.1 - 0.027 14.0 0.1 0.14 11.7 0.1 2.3 1 1 1 2 2 2 0 EF hand EF-hand_5 PF13202.6 KDO27475.1 - 0.047 13.2 0.2 0.65 9.6 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF1843 PF08898.10 KDO27475.1 - 0.049 14.1 0.4 1.8 9.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) EF-hand_7 PF13499.6 KDO27475.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.2 3 0 0 3 3 2 0 EF-hand domain pair Mago_nashi PF02792.14 KDO27476.1 - 1.6e-74 248.7 1.0 1.8e-74 248.6 1.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Ras PF00071.22 KDO27477.1 - 7.5e-59 198.0 0.0 8.5e-59 197.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO27477.1 - 4.7e-34 117.2 0.0 7.3e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO27477.1 - 3.4e-15 55.9 0.0 4.7e-15 55.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO27477.1 - 0.0019 18.2 0.0 0.0031 17.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO27477.1 - 0.0049 16.4 0.1 0.023 14.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO27477.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO27477.1 - 0.056 13.3 0.0 10 6.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 KDO27477.1 - 0.087 12.2 0.1 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein ORMDL PF04061.14 KDO27478.1 - 9.5e-41 138.8 1.1 1.1e-40 138.6 1.1 1.0 1 0 0 1 1 1 1 ORMDL family DUF4713 PF15831.5 KDO27478.1 - 0.27 11.7 0.2 0.27 11.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) STIL_N PF15253.6 KDO27479.1 - 2.7e-14 53.0 2.0 3.9e-14 52.4 1.2 1.6 2 0 0 2 2 2 1 SCL-interrupting locus protein N-terminus FlxA PF14282.6 KDO27479.1 - 0.028 14.4 8.5 0.047 13.7 8.5 1.3 1 0 0 1 1 1 0 FlxA-like protein MPS2 PF17060.5 KDO27479.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 SlyX PF04102.12 KDO27479.1 - 0.71 10.5 6.1 1.5 9.5 6.1 1.5 1 0 0 1 1 1 0 SlyX TRAPPC-Trs85 PF12739.7 KDO27480.1 - 1.1e-63 215.6 7.6 1.1e-62 212.3 7.6 2.0 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Asp_Arg_Hydrox PF05118.15 KDO27481.1 - 2.8e-09 37.0 0.3 5.7e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_1 PF00685.27 KDO27481.1 - 1.4e-08 34.6 0.0 2.9e-07 30.2 0.0 2.7 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KDO27481.1 - 3.5e-07 30.8 0.1 0.0003 21.3 0.0 3.5 3 1 0 3 3 3 1 Sulfotransferase family Corona_M PF01635.18 KDO27484.1 - 0.0063 15.9 1.9 1.6 7.9 0.2 2.1 2 0 0 2 2 2 2 Coronavirus M matrix/glycoprotein Cadherin_C_2 PF16492.5 KDO27484.1 - 0.024 15.4 0.0 0.073 13.8 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4448 PF14610.6 KDO27484.1 - 0.062 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ISK_Channel PF02060.15 KDO27484.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel EphA2_TM PF14575.6 KDO27484.1 - 0.18 12.7 0.0 0.6 11.0 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Atg14 PF10186.9 KDO27485.1 - 5.2e-09 35.6 7.2 3.9e-08 32.8 7.2 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 RRN3 PF05327.11 KDO27485.1 - 0.38 9.2 5.3 0.044 12.3 1.1 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FANCI_S2 PF14676.6 KDO27486.1 - 0.00087 19.6 2.8 0.00087 19.6 2.8 4.2 3 1 0 4 4 4 1 FANCI solenoid 2 Popeye PF04831.13 KDO27486.1 - 0.089 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Popeye protein conserved region DLP_helical PF18709.1 KDO27486.1 - 0.46 9.6 3.9 0.4 9.8 2.3 1.6 2 0 0 2 2 2 0 Dynamin-like helical domain DUF1759 PF03564.15 KDO27486.1 - 5.1 7.0 5.3 32 4.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) cNMP_binding PF00027.29 KDO27487.1 - 3.5e-59 196.9 0.6 7.3e-20 70.8 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase PF00069.25 KDO27487.1 - 1.2e-54 185.5 0.0 2.1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27487.1 - 1.6e-22 80.1 0.0 3.7e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27487.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like BTB_2 PF02214.22 KDO27488.1 - 3e-12 46.7 0.0 5.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 KDO27488.1 - 0.0034 17.5 0.0 0.0074 16.4 0.0 1.5 1 1 0 1 1 1 1 SPRY domain VASt PF16016.5 KDO27489.1 - 7.9e-24 84.8 0.0 2e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KDO27489.1 - 2.4e-16 59.6 0.3 2e-15 56.7 0.1 2.3 2 0 0 2 2 2 1 GRAM domain FCH PF00611.23 KDO27489.1 - 1e-11 44.9 7.5 1.3e-08 35.0 0.1 4.1 5 0 0 5 5 5 2 Fes/CIP4, and EFC/F-BAR homology domain Microtub_bind PF13931.6 KDO27489.1 - 0.019 15.4 4.6 1.4 9.3 0.1 3.7 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding HalX PF08663.10 KDO27489.1 - 0.14 12.5 2.8 14 6.1 0.2 3.7 2 0 0 2 2 2 0 HalX domain Pup PF05639.11 KDO27489.1 - 0.22 12.5 13.1 6.8 7.7 0.8 4.1 3 0 0 3 3 3 0 Pup-like protein TSNAXIP1_N PF15739.5 KDO27490.1 - 0.00027 21.3 0.5 0.002 18.5 0.5 2.0 1 1 0 1 1 1 1 Translin-associated factor X-interacting N-terminus eIF-1a PF01176.19 KDO27491.1 - 0.0081 15.9 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 GBP PF02263.19 KDO27493.1 - 1.5e-54 185.0 0.0 3e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KDO27493.1 - 1.2e-16 61.0 7.7 1.2e-16 61.0 7.7 2.4 1 1 2 3 3 3 1 Guanylate-binding protein, C-terminal domain HIP1_clath_bdg PF16515.5 KDO27493.1 - 0.021 15.4 8.1 0.021 15.4 8.1 4.4 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MMR_HSR1 PF01926.23 KDO27493.1 - 0.029 14.5 0.0 0.097 12.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Tup_N PF08581.10 KDO27493.1 - 0.1 12.9 3.1 0.38 11.1 0.5 3.1 1 1 2 3 3 3 0 Tup N-terminal DUF2730 PF10805.8 KDO27493.1 - 0.11 12.6 11.5 2.9 8.1 0.4 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF2730) CENP-F_leu_zip PF10473.9 KDO27493.1 - 0.51 10.4 26.8 0.036 14.1 9.2 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KDO27493.1 - 1.2 7.9 29.7 0.018 13.9 13.7 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 KDO27493.1 - 2.8 8.3 13.0 0.22 11.8 1.1 3.6 2 1 0 3 3 3 0 Uncharacterized conserved protein ADIP PF11559.8 KDO27493.1 - 3 7.9 28.9 0.44 10.6 4.2 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 KDO27493.1 - 8.6 6.0 12.6 0.54 9.9 2.3 2.4 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4486 PF14858.6 KDO27494.1 - 4.2e-14 51.9 0.5 2.5e-11 42.8 0.4 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4486) TPR_19 PF14559.6 KDO27494.1 - 0.25 11.9 2.9 0.63 10.6 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat C12orf66_like PF09404.10 KDO27495.1 - 9.6e-19 67.5 7.3 1.4e-08 34.0 0.1 4.0 4 0 0 4 4 4 3 KICSTOR complex C12orf66 like FtsX_ECD PF18075.1 KDO27495.1 - 0.095 13.3 0.2 0.57 10.9 0.0 2.1 1 1 1 2 2 2 0 FtsX extracellular domain ThiF PF00899.21 KDO27496.1 - 1.2e-70 237.7 0.1 1.7e-70 237.2 0.1 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KDO27496.1 - 4.4e-19 68.9 0.0 1.1e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KDO27496.1 - 3.5e-10 40.3 0.2 6.5e-06 26.2 0.1 3.0 1 1 2 3 3 3 2 Ubiquitin-activating enzyme active site E2_bind PF08825.10 KDO27496.1 - 5.1e-08 33.0 0.0 9.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain NAD_binding_7 PF13241.6 KDO27496.1 - 9.3e-05 22.8 0.1 0.00025 21.4 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KDO27496.1 - 0.002 18.2 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KDO27496.1 - 0.0025 18.1 0.7 0.0079 16.4 0.7 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KDO27496.1 - 0.12 12.9 0.2 0.36 11.4 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 KDO27496.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain EF-hand_1 PF00036.32 KDO27498.1 - 1.7e-25 86.6 3.0 9.5e-06 24.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO27498.1 - 7.9e-20 69.0 3.6 4.3e-06 26.2 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KDO27498.1 - 1.3e-19 70.4 5.2 1e-10 41.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO27498.1 - 2.4e-17 62.5 11.3 6.6e-07 29.1 0.3 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO27498.1 - 1.4e-14 52.8 1.6 0.0034 16.8 0.0 4.6 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 KDO27498.1 - 0.085 13.2 0.0 0.99 9.8 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CBF PF03914.17 KDO27499.1 - 1.8e-30 106.2 4.9 2.1e-28 99.5 1.3 2.3 2 0 0 2 2 2 2 CBF/Mak21 family DUF4611 PF15387.6 KDO27499.1 - 0.0025 18.0 6.5 0.0066 16.6 6.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) GCIP PF13324.6 KDO27499.1 - 0.012 15.2 2.6 0.56 9.8 1.1 2.7 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting HEAT_2 PF13646.6 KDO27499.1 - 0.021 15.2 0.3 0.6 10.5 0.1 3.2 2 1 0 2 2 2 0 HEAT repeats FAM176 PF14851.6 KDO27499.1 - 0.063 12.9 1.8 0.15 11.7 1.8 1.6 1 0 0 1 1 1 0 FAM176 family SURF2 PF05477.11 KDO27499.1 - 0.1 12.3 2.0 0.21 11.3 2.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RXT2_N PF08595.11 KDO27499.1 - 0.13 12.2 1.7 0.33 11.0 1.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4637 PF15470.6 KDO27499.1 - 0.2 11.4 1.5 0.4 10.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Sporozoite_P67 PF05642.11 KDO27499.1 - 0.23 9.5 1.2 0.33 9.0 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 KDO27499.1 - 0.27 10.9 8.7 1 9.1 8.7 1.9 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KDO27499.1 - 0.47 8.5 13.2 3.2 5.7 9.3 2.2 2 0 0 2 2 2 0 DNA polymerase phi YL1 PF05764.13 KDO27499.1 - 0.72 9.9 6.8 0.073 13.2 2.1 1.7 2 0 0 2 2 2 0 YL1 nuclear protein TPPII_N PF12583.8 KDO27499.1 - 0.99 10.0 5.9 0.78 10.3 0.3 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal PBP1_TM PF14812.6 KDO27499.1 - 1.5 9.2 12.1 0.15 12.5 7.0 2.0 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 KDO27499.1 - 1.9 7.6 11.2 3.6 6.6 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 KDO27499.1 - 2.3 8.7 14.3 0.42 11.0 10.5 1.7 2 0 0 2 2 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO27499.1 - 2.3 7.4 10.1 4.8 6.4 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 KDO27499.1 - 7.2 4.5 5.7 12 3.7 5.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rotamase PF00639.21 KDO27500.1 - 4.3e-20 72.5 1.3 5.4e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KDO27500.1 - 2e-14 54.1 0.9 2.2e-13 50.8 0.0 2.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain WW PF00397.26 KDO27500.1 - 2.7e-05 24.2 1.4 6e-05 23.0 1.4 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 KDO27500.1 - 0.0018 19.1 0.0 0.0036 18.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain ASH PF15780.5 KDO27501.1 - 2.6e-05 24.4 0.0 0.041 14.1 0.0 3.7 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KDO27501.1 - 0.00082 19.6 0.1 0.12 12.7 0.0 2.8 2 0 0 2 2 2 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 KDO27501.1 - 0.003 17.4 0.1 0.01 15.6 0.1 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Transglut_C PF00927.22 KDO27501.1 - 0.081 13.1 0.0 13 6.0 0.0 3.3 3 0 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain Pex14_N PF04695.13 KDO27502.1 - 0.0087 16.7 1.4 0.012 16.3 1.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sensor PF13796.6 KDO27502.1 - 0.014 15.5 3.7 0.02 14.9 3.7 1.3 1 0 0 1 1 1 0 Putative sensor PalH PF08733.10 KDO27502.1 - 0.06 12.3 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Ion_trans PF00520.31 KDO27503.1 - 4.8e-18 65.3 4.4 6e-18 65.0 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO27503.1 - 5.7e-10 39.0 4.9 5.7e-10 39.0 4.9 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KDO27504.1 - 5.4e-20 71.7 15.5 6.9e-20 71.3 15.5 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO27504.1 - 5.6e-11 42.3 7.7 5.6e-11 42.3 7.7 2.5 2 0 0 2 2 2 1 Ion channel DUF4231 PF14015.6 KDO27504.1 - 1.7 9.2 9.1 1.3 9.5 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Tetraspanin PF00335.20 KDO27505.1 - 0.32 10.7 2.7 0.39 10.4 2.7 1.1 1 0 0 1 1 1 0 Tetraspanin family HEAT_2 PF13646.6 KDO27506.1 - 5.7e-11 42.6 1.7 0.2 12.1 0.0 7.6 7 1 2 9 9 9 3 HEAT repeats Importin_rep_4 PF18808.1 KDO27506.1 - 1.2e-09 38.3 6.6 2.8e-09 37.1 0.0 4.0 4 0 0 4 4 4 1 Importin repeat HEAT PF02985.22 KDO27506.1 - 6.9e-08 32.1 3.2 22 5.7 0.0 8.7 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 KDO27506.1 - 4.1e-06 27.2 6.7 1 10.0 0.0 7.4 7 1 1 8 8 8 2 HEAT-like repeat DUF3385 PF11865.8 KDO27506.1 - 0.00012 22.0 4.9 0.4 10.6 0.0 5.3 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) MtrH PF02007.18 KDO27506.1 - 0.014 14.5 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit CLASP_N PF12348.8 KDO27506.1 - 0.016 14.7 4.1 1.1 8.8 0.2 3.9 4 0 0 4 4 4 0 CLASP N terminal Arm PF00514.23 KDO27506.1 - 0.034 14.2 2.8 12 6.1 0.1 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF577 PF04510.12 KDO27506.1 - 0.099 12.5 1.9 0.6 10.0 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF577) MAP17 PF15807.5 KDO27507.1 - 2.7 8.2 4.7 1.2 9.4 1.3 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Pou PF00157.17 KDO27508.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain E1-E2_ATPase PF00122.20 KDO27509.1 - 6e-45 153.0 0.6 6e-45 153.0 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KDO27509.1 - 3.8e-13 48.9 0.0 8.7e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KDO27509.1 - 4.1e-10 40.3 0.0 1.4e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAM176 PF14851.6 KDO27509.1 - 0.15 11.7 0.4 0.7 9.6 0.1 2.0 2 0 0 2 2 2 0 FAM176 family CAP_GLY PF01302.25 KDO27510.1 - 1.8e-17 63.1 0.2 3.1e-17 62.3 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KDO27510.1 - 2e-17 63.0 6.1 0.00041 20.7 0.4 5.1 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO27510.1 - 8.5e-11 41.5 14.1 0.00013 21.7 0.0 4.4 2 2 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KDO27510.1 - 3.8e-09 36.3 0.0 2.2e-05 24.0 0.0 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KDO27510.1 - 1e-05 25.2 1.2 3.5 7.9 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 KDO27510.1 - 0.0049 17.2 4.2 38 5.4 0.0 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat Ubiquitin_2 PF14560.6 KDO27510.1 - 0.048 14.1 0.2 1.1 9.8 0.1 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain Dpy-30 PF05186.13 KDO27511.1 - 6.9e-15 54.5 0.0 1.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 KDO27511.1 - 1.8e-06 28.2 0.0 1.3e-05 25.3 0.0 2.3 3 0 0 3 3 3 1 Adenylate kinase AAA_17 PF13207.6 KDO27511.1 - 6e-05 23.5 0.0 0.0016 18.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KDO27511.1 - 0.00018 22.0 0.0 0.061 13.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain Hydin_ADK PF17213.3 KDO27511.1 - 0.0039 17.5 1.6 0.089 13.1 0.0 2.6 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_14 PF13173.6 KDO27511.1 - 0.005 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO27511.1 - 0.011 16.1 0.4 0.092 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KDO27511.1 - 0.081 13.2 0.4 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO27511.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO27511.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ANF_receptor PF01094.28 KDO27511.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region AAA PF00004.29 KDO27511.1 - 0.33 11.4 1.0 0.6 10.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ion_trans PF00520.31 KDO27512.1 - 6.9e-126 418.5 56.1 8.5e-44 149.6 10.2 3.1 3 0 0 3 3 3 3 Ion transport protein GPHH PF16905.5 KDO27512.1 - 5.4e-07 29.3 0.0 1.7e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KDO27512.1 - 1e-06 27.7 62.6 0.0034 16.1 1.0 8.1 6 2 2 8 8 8 6 Polycystin cation channel Ion_trans PF00520.31 KDO27513.1 - 3.5e-44 150.9 3.9 4.5e-44 150.5 3.9 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KDO27513.1 - 0.2 10.3 8.1 2.8 6.5 0.2 2.3 2 0 0 2 2 2 0 Polycystin cation channel DUF3742 PF12553.8 KDO27513.1 - 4.8 7.3 13.9 22 5.2 0.1 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3742) GATase_2 PF00310.21 KDO27514.1 - 4.4e-161 536.3 0.0 5.9e-161 535.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KDO27514.1 - 4e-152 506.6 0.5 7.7e-150 499.1 0.1 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KDO27514.1 - 6.3e-103 344.1 0.0 1.2e-102 343.1 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 KDO27514.1 - 3.3e-73 245.4 1.8 5.6e-73 244.6 1.8 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 KDO27514.1 - 0.13 11.3 0.8 0.3 10.1 0.5 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pyr_redox_2 PF07992.14 KDO27515.1 - 8e-29 100.8 0.1 1.4e-27 96.7 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KDO27515.1 - 9.9e-22 76.8 0.1 1.5e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KDO27515.1 - 4.3e-11 42.9 0.0 5e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KDO27515.1 - 2.1e-08 34.6 0.2 0.00058 20.4 0.3 3.6 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO27515.1 - 6.8e-08 32.1 0.1 0.0011 18.3 0.0 3.5 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO27515.1 - 6.1e-07 28.5 0.2 7.6e-05 21.6 0.4 2.3 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KDO27515.1 - 3.5e-06 26.6 0.7 1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KDO27515.1 - 1.5e-05 24.5 0.1 1.5e-05 24.5 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KDO27515.1 - 2.6e-05 24.0 0.6 0.015 14.9 0.4 2.9 2 2 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KDO27515.1 - 3.2e-05 24.3 0.0 0.41 11.1 0.0 2.8 3 0 0 3 3 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KDO27515.1 - 4.7e-05 22.6 2.8 0.00011 21.4 0.3 2.7 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KDO27515.1 - 7.1e-05 22.2 0.3 0.00021 20.7 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KDO27515.1 - 0.00013 21.3 0.0 0.056 12.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KDO27515.1 - 0.00045 19.6 0.0 0.078 12.3 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KDO27515.1 - 0.00061 19.0 0.4 0.026 13.6 0.3 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.18 KDO27515.1 - 0.0011 19.1 0.0 1.4 9.2 0.0 2.8 3 0 0 3 3 2 2 TrkA-N domain FMO-like PF00743.19 KDO27515.1 - 0.003 16.0 0.1 1.9 6.8 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like YjeF_N PF03853.15 KDO27515.1 - 0.0039 17.1 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 1 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.23 KDO27515.1 - 0.0063 16.5 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KDO27515.1 - 0.0076 16.3 0.0 8.9 6.4 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KDO27515.1 - 0.0077 15.5 0.2 0.039 13.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KDO27515.1 - 0.01 15.8 2.3 0.41 10.6 0.1 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KDO27515.1 - 0.021 14.0 0.2 4 6.5 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Rossmann-like PF10727.9 KDO27515.1 - 0.057 13.3 0.3 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Rossmann-like domain Lycopene_cycl PF05834.12 KDO27515.1 - 0.062 12.3 0.2 0.33 9.9 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 KDO27515.1 - 0.08 13.0 0.3 1.9 8.5 0.0 2.4 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SCIFF PF13165.6 KDO27515.1 - 0.19 11.7 1.2 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF LRR_4 PF12799.7 KDO27516.1 - 1.2e-22 79.6 2.5 0.019 15.4 0.1 11.0 8 3 6 14 14 14 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO27516.1 - 1.1e-09 37.5 43.9 5.4 7.3 0.1 18.0 19 1 1 20 20 20 4 Leucine Rich repeat Coatomer_g_Cpla PF16381.5 KDO27516.1 - 0.013 15.7 3.5 48 4.1 0.3 5.1 5 1 1 6 6 6 0 Coatomer subunit gamma-1 C-terminal appendage platform Hexapep_loop PF18776.1 KDO27516.1 - 0.67 9.6 3.1 39 4.0 0.2 3.7 3 0 0 3 3 3 0 Hexapeptide repeat including loop LRR_1 PF00560.33 KDO27516.1 - 0.76 10.6 39.2 13 6.8 0.0 14.6 13 6 0 13 13 13 0 Leucine Rich Repeat Ank_2 PF12796.7 KDO27517.1 - 1.7e-38 131.1 2.1 7.6e-14 52.1 0.0 4.7 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27517.1 - 4.7e-34 116.3 5.3 1.2e-09 38.5 0.3 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27517.1 - 1.1e-33 114.8 11.7 6e-08 32.8 0.1 6.9 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27517.1 - 4.6e-26 88.0 9.9 0.00013 22.1 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KDO27517.1 - 1.2e-18 66.7 8.5 0.00029 21.1 0.1 7.7 7 1 1 8 8 8 5 Ankyrin repeat Ank_2 PF12796.7 KDO27518.1 - 1.1e-44 150.9 1.1 1.2e-16 61.0 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27518.1 - 1.2e-39 134.2 6.3 1.1e-09 38.6 0.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27518.1 - 7.9e-35 118.5 6.5 6.2e-10 39.1 0.1 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27518.1 - 4.5e-29 97.3 3.9 0.0001 22.4 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KDO27518.1 - 8.2e-25 86.1 5.8 7e-06 26.3 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat SAM_1 PF00536.30 KDO27518.1 - 3.4e-15 56.2 0.1 7.4e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO27518.1 - 1.7e-13 50.4 0.1 3.4e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FAM183 PF14886.6 KDO27519.1 - 2.1e-17 63.8 1.4 2.5e-17 63.5 1.4 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.6 KDO27519.1 - 0.00031 21.3 1.5 0.00046 20.7 1.5 1.3 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF3027 PF11228.8 KDO27519.1 - 0.016 15.3 0.2 0.021 14.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) PMP1_2 PF08114.11 KDO27520.1 - 0.031 14.0 0.1 0.031 14.0 0.1 2.1 2 0 0 2 2 2 0 ATPase proteolipid family Glyco_hydro_17 PF00332.18 KDO27520.1 - 0.06 12.9 6.2 0.024 14.2 2.3 2.2 2 1 1 3 3 3 0 Glycosyl hydrolases family 17 DUF4366 PF14283.6 KDO27520.1 - 6.6 6.8 8.1 1.7 8.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) LRR_6 PF13516.6 KDO27521.1 - 5.9e-14 50.9 16.1 0.00059 19.7 0.3 8.5 10 0 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.6 KDO27521.1 - 2.6e-09 36.7 3.4 0.00016 21.4 0.5 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 KDO27521.1 - 6.1e-07 29.1 5.9 30 5.7 0.1 8.1 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO27521.1 - 0.0018 18.6 11.2 1.5 9.4 0.4 6.0 4 3 2 6 6 6 2 Leucine Rich repeats (2 copies) CLZ PF16526.5 KDO27521.1 - 0.12 12.8 0.9 3 8.3 0.0 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KDO27521.1 - 0.12 12.9 0.2 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KDO27521.1 - 0.14 12.4 0.4 8.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KDO27521.1 - 0.35 11.0 4.1 11 6.2 1.8 2.3 2 0 0 2 2 2 0 Tropomyosin like Ribosomal_L41 PF05162.13 KDO27522.1 - 5.7e-08 32.7 33.2 7e-08 32.4 33.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L41 ubiquitin PF00240.23 KDO27522.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO27522.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SAC3_GANP PF03399.16 KDO27524.1 - 8.8e-83 278.1 1.2 1.5e-82 277.3 0.0 1.8 2 0 0 2 2 2 1 SAC3/GANP family Asp-B-Hydro_N PF05279.11 KDO27524.1 - 0.63 10.1 20.5 1.2 9.1 20.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nucleoporin_FG PF13634.6 KDO27524.1 - 6 7.8 122.5 3.5 8.5 25.4 4.7 1 1 3 4 4 4 0 Nucleoporin FG repeat region LTV PF04180.14 KDO27524.1 - 7.4 6.2 11.0 11 5.6 11.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein Mic1 PF07035.12 KDO27525.1 - 1.7e-12 47.4 0.1 2.8e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DUF2046 PF09755.9 KDO27526.1 - 4.9e-09 35.8 16.9 6.6e-05 22.3 2.9 2.7 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) PolyA_pol PF01743.20 KDO27526.1 - 0.011 16.2 0.9 0.022 15.2 0.9 1.6 1 0 0 1 1 1 0 Poly A polymerase head domain Diphthami_syn_2 PF01902.17 KDO27526.1 - 0.018 14.6 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Diphthamide synthase HAGH_C PF16123.5 KDO27526.1 - 4 8.0 8.5 0.65 10.6 2.9 2.5 3 1 1 4 4 4 0 Hydroxyacylglutathione hydrolase C-terminus Mre11_DNA_bind PF04152.14 KDO27527.1 - 7.5e-41 140.3 0.5 3.3e-39 134.9 0.0 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KDO27527.1 - 1.2e-10 42.2 2.2 1.2e-09 39.0 2.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO27527.1 - 9e-05 22.7 0.0 0.00093 19.4 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HSF_DNA-bind PF00447.17 KDO27529.1 - 2e-25 89.2 3.0 3e-25 88.7 3.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DNA_pol_B_exo2 PF10108.9 KDO27529.1 - 0.0063 16.2 0.1 0.0098 15.6 0.1 1.2 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Peptidase_M17 PF00883.21 KDO27530.1 - 6.5e-111 370.5 0.5 8e-111 370.2 0.5 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KDO27530.1 - 3.5e-09 36.6 0.1 1.2e-08 34.9 0.0 2.1 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Pkinase_Tyr PF07714.17 KDO27532.1 - 4.8e-60 203.0 0.0 6.7e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO27532.1 - 5e-60 203.1 0.0 7.6e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO27532.1 - 0.0047 15.7 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO27532.1 - 0.0084 16.1 0.2 0.88 9.4 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO27532.1 - 0.16 10.9 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain LRR_4 PF12799.7 KDO27533.1 - 2.3e-11 43.7 0.1 0.21 12.0 0.0 5.3 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO27533.1 - 1.1e-08 34.5 2.4 3.8 7.8 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 KDO27533.1 - 0.0058 16.4 2.3 0.22 11.3 0.5 3.7 3 2 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KDO27533.1 - 0.92 10.3 6.3 1.5e+02 3.6 0.0 5.7 8 0 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 KDO27533.1 - 5.4 7.3 5.8 8.6 6.7 0.1 3.6 3 2 1 4 4 4 0 Ste50p, sterile alpha motif Amidohydro_1 PF01979.20 KDO27534.1 - 5.6e-66 223.2 3.3 7.5e-66 222.8 3.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KDO27534.1 - 1.3e-55 186.9 1.5 2.8e-55 185.8 1.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 KDO27534.1 - 7.1e-43 144.9 0.9 2.1e-42 143.4 0.1 2.3 3 0 0 3 3 3 1 Urease, gamma subunit Urease_beta PF00699.20 KDO27534.1 - 1.4e-35 121.3 0.0 3e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 KDO27534.1 - 6.6e-06 25.9 6.6 1.1e-05 25.2 0.6 2.3 1 1 1 2 2 2 2 Amidohydrolase family Phospholip_B PF04916.13 KDO27535.1 - 1.1e-149 499.4 0.0 1.4e-149 499.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B WD40 PF00400.32 KDO27536.1 - 9.9e-33 111.7 31.5 5.6e-05 23.8 0.0 11.0 11 1 1 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27536.1 - 4.4e-19 68.6 0.4 0.0015 18.8 0.0 6.6 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO27536.1 - 0.00052 19.4 0.0 0.23 10.8 0.0 3.7 4 1 0 4 4 4 2 WD40-like domain PQQ PF01011.21 KDO27536.1 - 0.058 13.3 0.9 5 7.2 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat DUF1513 PF07433.11 KDO27536.1 - 0.065 12.3 0.2 8.1 5.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) Pkinase PF00069.25 KDO27537.1 - 1.6e-42 145.8 0.0 2.2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27537.1 - 5.9e-42 143.7 0.0 8.3e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO27537.1 - 0.048 13.6 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO27537.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO27537.1 - 0.18 10.7 0.0 0.45 9.4 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Cation_efflux PF01545.21 KDO27538.1 - 7e-22 78.1 17.3 8.5e-22 77.9 17.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KDO27538.1 - 5.1e-10 39.3 0.2 1.5e-09 37.8 0.2 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Elicitin PF00964.17 KDO27539.1 - 0.00056 20.0 0.1 0.00076 19.5 0.1 1.2 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO27540.1 - 0.0024 18.0 0.1 0.0043 17.1 0.1 1.4 1 0 0 1 1 1 1 Elicitin TFIID-18kDa PF02269.16 KDO27542.1 - 4.4e-18 65.1 0.1 7.4e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KDO27542.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated EF-hand_1 PF00036.32 KDO27543.1 - 3.7e-17 60.5 10.9 2.9e-05 23.3 0.3 4.9 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO27543.1 - 1.3e-16 60.8 9.4 4.8e-08 33.3 0.9 3.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO27543.1 - 7.3e-15 54.6 12.6 3.4e-09 36.4 0.6 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO27543.1 - 6.5e-12 44.4 15.4 0.0018 18.1 0.2 5.0 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KDO27543.1 - 4.6e-06 25.9 19.9 0.0027 17.1 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 KDO27543.1 - 0.0031 17.4 0.4 0.59 10.1 0.0 2.9 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KDO27543.1 - 0.031 14.6 2.3 1.2 9.5 0.0 2.8 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 KDO27543.1 - 0.76 9.7 5.0 19 5.1 0.1 3.7 3 1 1 4 4 4 0 Caleosin related protein RGS PF00615.19 KDO27544.1 - 1.7e-67 225.0 8.5 2.5e-17 63.2 0.2 4.2 4 0 0 4 4 4 4 Regulator of G protein signaling domain YkyB PF14177.6 KDO27544.1 - 0.1 12.9 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 0 YkyB-like protein RGS PF00615.19 KDO27545.1 - 3e-72 240.4 8.1 1.5e-20 73.6 0.1 5.1 6 0 0 6 6 6 4 Regulator of G protein signaling domain eIF3_p135 PF12807.7 KDO27545.1 - 0.081 12.9 0.7 0.39 10.7 0.0 2.4 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit 135 FliL PF03748.14 KDO27545.1 - 0.24 12.0 1.0 6 7.5 0.0 3.4 3 2 0 3 3 3 0 Flagellar basal body-associated protein FliL Baculo_PEP_C PF04513.12 KDO27546.1 - 0.16 12.0 0.6 38 4.3 0.0 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FGE-sulfatase PF03781.16 KDO27547.1 - 1.9e-23 83.3 1.9 5.2e-23 82.0 1.9 1.8 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KDO27547.1 - 1.9e-06 28.4 2.2 3.5e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 DinB superfamily MIF PF01187.18 KDO27548.1 - 0.19 12.0 0.3 0.73 10.2 0.1 2.0 1 1 1 2 2 2 0 Macrophage migration inhibitory factor (MIF) DUF3523 PF12037.8 KDO27548.1 - 0.8 9.0 15.7 1 8.7 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Pox_Ag35 PF03286.14 KDO27548.1 - 4.9 6.9 13.1 7.1 6.4 13.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Chromate_transp PF02417.15 KDO27550.1 - 0.58 10.3 9.4 0.72 10.0 5.1 2.2 2 0 0 2 2 2 0 Chromate transporter PLAC8 PF04749.17 KDO27551.1 - 1.7e-08 35.4 6.2 3.1e-08 34.5 6.2 1.4 1 1 0 1 1 1 1 PLAC8 family START PF01852.19 KDO27553.1 - 2.1e-07 30.6 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO27553.1 - 5.1e-07 29.7 14.5 1.4e-06 28.4 14.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27553.1 - 0.00041 20.5 6.2 0.00072 19.8 6.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger LRR_8 PF13855.6 KDO27554.1 - 2.4e-20 72.0 22.0 1.9e-05 24.3 0.0 6.6 4 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KDO27554.1 - 2.1e-15 56.6 33.0 0.00042 20.6 1.4 8.1 3 2 6 10 10 10 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO27554.1 - 0.00068 19.5 24.5 0.59 10.3 0.1 8.0 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 KDO27554.1 - 0.0017 18.6 15.0 5 8.1 0.2 7.5 6 3 1 7 7 7 2 Leucine Rich Repeat FNIP PF05725.12 KDO27554.1 - 0.83 9.9 18.7 2.1 8.6 1.2 4.9 3 2 1 4 4 4 0 FNIP Repeat Aa_trans PF01490.18 KDO27556.1 - 1.5e-34 119.4 18.3 2.8e-34 118.5 18.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KDO27557.1 - 1.2e-43 149.3 23.0 1.5e-43 149.0 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO27557.1 - 2.5e-06 26.8 8.5 2.5e-06 26.8 8.5 3.0 2 1 0 3 3 3 1 Tryptophan/tyrosine permease family RAMP PF04901.13 KDO27557.1 - 3.1 7.9 5.4 26 4.8 0.0 3.9 4 0 0 4 4 4 0 Receptor activity modifying family Elicitin PF00964.17 KDO27558.1 - 3.6e-05 23.8 0.9 0.12 12.5 0.1 2.4 2 0 0 2 2 2 2 Elicitin Spt4 PF06093.13 KDO27558.1 - 0.046 13.8 0.0 6.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Rubis-subs-bind PF09273.11 KDO27559.1 - 3.9e-12 47.0 0.0 7.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KDO27559.1 - 8.2e-10 39.3 0.0 1.5e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 SET domain FYVE PF01363.21 KDO27560.1 - 2.4e-08 34.0 9.2 4.9e-08 33.0 9.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27560.1 - 0.00028 21.1 3.5 0.00054 20.2 3.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 KDO27560.1 - 0.0057 16.8 1.4 0.016 15.4 1.4 1.8 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain C1_1 PF00130.22 KDO27560.1 - 0.29 11.1 6.1 0.9 9.5 6.1 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KDO27560.1 - 4.5 7.7 8.9 12 6.3 8.9 1.8 1 0 0 1 1 1 0 Ring finger domain Abhydrolase_2 PF02230.16 KDO27561.1 - 3.6e-52 177.3 0.0 4.5e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KDO27561.1 - 2.3e-09 37.0 3.4 8e-07 28.8 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KDO27561.1 - 3.2e-08 34.4 0.4 3.2e-07 31.2 0.3 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KDO27561.1 - 3.8e-07 29.8 0.0 0.00011 21.8 0.0 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase DLH PF01738.18 KDO27561.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KDO27561.1 - 0.00022 20.6 1.7 0.037 13.3 0.0 3.1 2 1 1 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KDO27561.1 - 0.00027 20.6 0.0 0.0016 18.1 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KDO27561.1 - 0.00072 19.5 0.5 0.041 13.7 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KDO27561.1 - 0.0099 15.5 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KDO27561.1 - 0.064 11.9 0.1 0.15 10.7 0.1 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) LIP PF03583.14 KDO27561.1 - 0.13 11.5 0.3 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Secretory lipase BT1 PF03092.16 KDO27562.1 - 8.9e-08 30.8 5.0 1.8e-07 29.8 0.6 2.3 2 0 0 2 2 2 2 BT1 family RCC1 PF00415.18 KDO27563.1 - 1.1e-48 163.7 12.2 2e-13 50.7 1.3 6.4 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO27563.1 - 1.6e-23 81.9 20.4 2.6e-05 23.9 0.1 5.7 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat SHIPPO-rpt PF07004.12 KDO27563.1 - 0.0097 16.8 8.3 0.13 13.2 0.7 3.4 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat Ribosomal_S5 PF00333.20 KDO27563.1 - 7.7 6.6 6.5 2.7 8.0 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein S5, N-terminal domain zf-met2 PF12907.7 KDO27564.1 - 6.9e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding Ig_2 PF13895.6 KDO27564.1 - 0.024 15.0 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain zf-C2H2_4 PF13894.6 KDO27564.1 - 0.037 14.9 0.2 0.061 14.2 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3128 PF11326.8 KDO27565.1 - 4e-17 62.4 0.2 4.6e-17 62.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) START PF01852.19 KDO27566.1 - 1e-07 31.6 0.1 1.6e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO27566.1 - 0.0043 17.3 7.8 0.0079 16.4 7.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO27566.1 - 0.13 12.4 21.2 0.34 11.1 21.2 1.6 1 1 0 1 1 1 0 FYVE zinc finger Sec23_trunk PF04811.15 KDO27567.1 - 1.1e-42 146.3 0.0 1.7e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KDO27567.1 - 2.2e-18 66.0 0.0 5.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KDO27567.1 - 2.1e-14 53.3 3.8 5e-14 52.1 3.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KDO27567.1 - 3.7e-14 53.2 0.0 6.9e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KDO27567.1 - 0.00077 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Telomere_reg-2 PF10193.9 KDO27568.1 - 5.4e-21 75.1 0.3 1.2e-20 74.0 0.3 1.6 1 0 0 1 1 1 1 Telomere length regulation protein Sugar_tr PF00083.24 KDO27569.1 - 2.2e-41 142.2 14.8 2.7e-41 141.9 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO27569.1 - 2.3e-28 99.1 44.4 5.4e-23 81.5 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KDO27569.1 - 1.7e-05 24.3 6.6 1.7e-05 24.3 6.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FYVE PF01363.21 KDO27570.1 - 9.5e-10 38.5 8.4 9.5e-10 38.5 8.4 1.7 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27570.1 - 0.00025 21.2 4.7 0.00046 20.4 4.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 KDO27570.1 - 0.19 11.9 5.6 0.53 10.6 5.6 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KDO27571.1 - 2.2e-08 34.1 9.7 2.2e-08 34.1 9.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger START PF01852.19 KDO27571.1 - 5e-07 29.3 0.5 1.3e-06 27.9 0.2 1.8 2 0 0 2 2 2 1 START domain FYVE_2 PF02318.16 KDO27571.1 - 0.0028 17.9 3.3 0.0028 17.9 3.3 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger Hva1_TUDOR PF11160.8 KDO27571.1 - 0.0074 16.4 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain C1_1 PF00130.22 KDO27571.1 - 0.14 12.1 6.2 0.34 10.8 6.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4428 PF14471.6 KDO27571.1 - 0.37 10.8 5.4 0.9 9.5 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zf-HIT PF04438.16 KDO27571.1 - 0.87 9.5 7.1 2.3 8.1 7.1 1.8 1 0 0 1 1 1 0 HIT zinc finger C1_2 PF03107.16 KDO27571.1 - 1.4 9.3 5.7 0.56 10.6 2.4 2.0 2 0 0 2 2 2 0 C1 domain DZR PF12773.7 KDO27571.1 - 2.3 8.3 5.5 1.4 9.0 2.6 2.2 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.21 KDO27571.1 - 2.9 8.2 8.4 15 5.9 8.4 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 KDO27571.1 - 9.1 6.5 7.8 98 3.2 7.8 2.4 1 1 0 1 1 1 0 B-box zinc finger PRCC PF10253.9 KDO27573.1 - 0.6 10.9 5.2 0.94 10.2 5.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting GTP_EFTU PF00009.27 KDO27574.1 - 2.8e-25 89.0 0.0 4e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KDO27574.1 - 4.8e-09 36.5 0.1 1.1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KDO27574.1 - 1.9e-07 31.4 0.9 2.3e-05 24.7 0.3 3.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO27574.1 - 3.7e-05 23.8 0.0 7.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO27574.1 - 0.00092 18.8 0.4 0.42 10.1 0.2 2.5 2 1 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO27574.1 - 0.0017 18.3 0.3 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KDO27574.1 - 0.0034 17.6 0.0 0.63 10.3 0.0 2.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Phage_base_V PF04717.12 KDO27574.1 - 0.026 14.5 0.0 3.3 7.7 0.0 2.3 1 1 0 2 2 2 0 Type VI secretion system, phage-baseplate injector ATP_bind_1 PF03029.17 KDO27574.1 - 0.07 12.9 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KDO27574.1 - 0.26 10.4 0.1 0.87 8.7 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Ank_2 PF12796.7 KDO27575.1 - 4.8e-08 33.5 3.1 0.0025 18.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27575.1 - 5.4e-08 33.2 3.7 0.00033 21.2 0.2 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27575.1 - 0.0029 17.9 4.9 0.17 12.3 0.1 4.0 1 1 3 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO27575.1 - 0.012 16.0 3.0 7.1 7.3 0.1 3.9 4 1 0 4 4 4 0 Ankyrin repeat Ank_3 PF13606.6 KDO27575.1 - 0.27 11.9 2.8 81 4.3 0.0 4.5 5 1 1 6 6 6 0 Ankyrin repeat C2 PF00168.30 KDO27576.1 - 3.3e-17 62.7 0.0 7.4e-17 61.5 0.0 1.6 2 0 0 2 2 2 1 C2 domain Ank_2 PF12796.7 KDO27577.1 - 6.5e-17 61.9 1.6 1.4e-08 35.2 0.5 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27577.1 - 4.7e-15 55.7 7.0 1.4e-05 25.5 0.6 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27577.1 - 4.2e-13 49.2 9.3 0.074 13.4 0.0 6.4 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27577.1 - 1.1e-07 31.6 7.0 3.7 8.4 0.0 6.9 6 2 2 8 8 8 3 Ankyrin repeat Ank PF00023.30 KDO27577.1 - 0.0025 18.2 6.6 18 6.0 1.1 5.3 1 1 1 2 2 2 2 Ankyrin repeat NUDIX PF00293.28 KDO27578.1 - 3.7e-16 59.4 0.7 6e-16 58.7 0.7 1.4 1 0 0 1 1 1 1 NUDIX domain START PF01852.19 KDO27579.1 - 8.3e-07 28.6 0.0 2.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 START domain FYVE PF01363.21 KDO27579.1 - 0.0023 18.0 5.0 0.0046 17.1 5.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27579.1 - 0.0029 17.8 3.3 0.0056 16.9 3.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger HsbA PF12296.8 KDO27579.1 - 0.054 13.9 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A FYVE PF01363.21 KDO27580.1 - 1.3e-10 41.3 15.0 1.3e-10 41.3 15.0 2.2 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27580.1 - 2.1e-05 24.7 7.0 2.1e-05 24.7 7.0 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger C1_2 PF03107.16 KDO27580.1 - 0.017 15.5 3.6 0.017 15.5 3.6 2.1 2 0 0 2 2 2 0 C1 domain zinc_ribbon_4 PF13717.6 KDO27580.1 - 0.059 13.3 14.1 0.46 10.5 10.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain COG7 PF10191.9 KDO27581.1 - 4.7e-54 183.9 0.4 5.5e-45 153.9 0.2 2.4 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) Hepatitis_core PF00906.20 KDO27581.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Hepatitis core antigen DUF717 PF05338.12 KDO27581.1 - 0.26 11.5 2.2 0.47 10.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF717) DUF3811 PF11656.8 KDO27582.1 - 0.021 15.2 0.2 0.034 14.5 0.2 1.2 1 0 0 1 1 1 0 YjbD family (DUF3811) DUF647 PF04884.14 KDO27583.1 - 1.5e-90 303.1 2.9 2.1e-90 302.6 2.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Mntp PF02659.15 KDO27583.1 - 0.0092 15.7 1.4 0.029 14.1 0.2 2.1 1 1 1 2 2 2 1 Putative manganese efflux pump 2OG-FeII_Oxy_3 PF13640.6 KDO27586.1 - 1.1e-11 45.5 0.4 1.9e-11 44.7 0.4 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KDO27586.1 - 2e-05 25.0 0.1 4.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMCCDC2 PF15844.5 KDO27586.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 zf-RING_2 PF13639.6 KDO27587.1 - 3.7e-12 46.4 6.5 3.7e-12 46.4 6.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KDO27587.1 - 1e-08 34.8 1.5 1e-08 34.8 1.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO27587.1 - 3.3e-07 30.0 7.5 3.3e-07 30.0 7.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO27587.1 - 6.1e-07 29.4 0.5 2.1e-06 27.7 0.5 1.8 1 1 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 KDO27587.1 - 1.2e-06 28.6 11.0 8.2e-06 26.0 11.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO27587.1 - 2.6e-06 27.2 5.5 6.4e-06 25.9 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO27587.1 - 9.9e-06 25.3 2.9 2e-05 24.3 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO27587.1 - 1e-05 25.5 1.2 1e-05 25.5 1.2 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO27587.1 - 6.2e-05 23.0 5.7 0.0013 18.7 5.7 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO27587.1 - 8.5e-05 22.3 4.6 0.00021 21.1 4.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO27587.1 - 0.00013 21.9 4.8 0.00013 21.9 4.8 2.0 2 0 0 2 2 1 1 zinc-RING finger domain SKN1 PF03935.15 KDO27588.1 - 6.3e-66 222.8 14.3 8e-30 103.7 0.1 4.6 2 2 1 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) TMIE PF16038.5 KDO27588.1 - 0.12 12.2 0.6 0.23 11.3 0.6 1.4 1 0 0 1 1 1 0 TMIE protein FGE-sulfatase PF03781.16 KDO27590.1 - 3.7e-19 69.3 3.6 2e-10 40.7 0.0 2.4 2 1 1 3 3 3 2 Sulfatase-modifying factor enzyme 1 HET PF06985.11 KDO27591.1 - 5.8e-13 49.4 0.1 2e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Bromodomain PF00439.25 KDO27592.1 - 2.1e-21 75.8 0.0 6e-21 74.3 0.0 1.8 2 0 0 2 2 1 1 Bromodomain PDZ PF00595.24 KDO27592.1 - 5.1e-10 39.6 1.4 0.012 16.0 1.6 3.9 3 0 0 3 3 3 2 PDZ domain PHD PF00628.29 KDO27592.1 - 1.8e-09 37.3 4.1 6.5e-09 35.6 4.1 2.1 1 0 0 1 1 1 1 PHD-finger PDZ_6 PF17820.1 KDO27592.1 - 5e-07 29.5 1.6 0.32 10.9 0.1 5.6 5 0 0 5 5 5 2 PDZ domain PDZ_2 PF13180.6 KDO27592.1 - 7.4e-06 26.2 0.7 2.1 8.7 0.0 5.0 5 0 0 5 5 5 2 PDZ domain FYRC PF05965.14 KDO27592.1 - 5.5e-05 23.2 0.0 0.00021 21.4 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus TFIIA PF03153.13 KDO27592.1 - 0.0007 19.7 53.2 0.0007 19.7 53.2 4.5 5 0 0 5 5 4 1 Transcription factor IIA, alpha/beta subunit WHIM1 PF15612.6 KDO27592.1 - 0.0018 17.8 0.2 0.005 16.3 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.6 KDO27592.1 - 0.025 14.5 3.6 0.088 12.8 3.6 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KDO27592.1 - 0.33 10.5 2.9 0.6 9.7 0.7 2.5 2 0 0 2 2 2 0 PHD-finger zf-TFIIB PF13453.6 KDO27592.1 - 0.46 9.9 2.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger ADH_zinc_N_2 PF13602.6 KDO27593.1 - 4.3e-16 60.2 0.0 1.2e-15 58.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KDO27593.1 - 3.2e-08 33.6 0.1 6.5e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO27593.1 - 5.8e-06 26.2 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HNF-1A_C PF04813.12 KDO27595.1 - 0.031 15.0 0.1 0.093 13.5 0.1 1.8 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF4131 PF13567.6 KDO27596.1 - 0.61 9.7 11.3 0.66 9.6 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4112 PF13430.6 KDO27597.1 - 0.097 13.0 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) DUF676 PF05057.14 KDO27601.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FAD_binding_3 PF01494.19 KDO27602.1 - 8e-14 51.6 1.1 5e-13 49.0 1.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KDO27602.1 - 4.1e-08 33.2 1.8 3e-06 27.1 1.6 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO27602.1 - 6.1e-06 26.4 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KDO27602.1 - 4.3e-05 24.0 0.0 0.00079 19.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KDO27602.1 - 6.5e-05 22.3 0.3 0.00012 21.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO27602.1 - 0.00023 20.4 0.1 0.00032 19.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KDO27602.1 - 0.00024 20.6 1.2 0.00043 19.7 1.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO27602.1 - 0.00099 17.9 0.1 0.0017 17.1 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KDO27602.1 - 0.0022 17.1 1.2 0.0049 16.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KDO27602.1 - 0.005 16.1 0.1 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KDO27602.1 - 0.0058 16.0 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SE PF08491.10 KDO27602.1 - 0.029 13.4 0.0 0.096 11.7 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.12 KDO27602.1 - 0.058 12.4 0.3 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KDO27602.1 - 0.09 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KDO27602.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.7 KDO27603.1 - 1.3e-07 31.4 0.1 0.0015 18.1 0.0 3.3 3 1 1 4 4 4 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO27603.1 - 8e-07 29.3 1.6 5.7e-06 26.5 0.2 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Asp_Arg_Hydrox PF05118.15 KDO27604.1 - 5.1e-31 107.6 0.0 7.4e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Methyltransf_11 PF08241.12 KDO27604.1 - 2.3e-12 47.4 0.0 4.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27604.1 - 9e-11 42.3 0.1 2.9e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO27604.1 - 9.6e-11 41.7 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO27604.1 - 8.2e-09 36.1 0.5 2.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO27604.1 - 3e-08 33.7 0.0 5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KDO27604.1 - 1e-05 25.2 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KDO27604.1 - 0.00081 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KDO27604.1 - 0.15 11.8 0.0 0.84 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TRAPP PF04051.16 KDO27605.1 - 3.3e-39 133.9 0.0 3.8e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component UVR PF02151.19 KDO27607.1 - 1.2e-06 28.0 22.1 2e-05 24.2 7.8 3.2 3 0 0 3 3 3 2 UvrB/uvrC motif F5_F8_type_C PF00754.25 KDO27607.1 - 1.8e-05 24.9 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 KDO27607.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain zf-Di19 PF05605.12 KDO27607.1 - 0.18 12.1 16.9 1.5 9.1 4.7 3.1 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FlxA PF14282.6 KDO27607.1 - 0.25 11.4 0.8 0.74 9.8 0.8 1.7 1 0 0 1 1 1 0 FlxA-like protein PRP21_like_P PF12230.8 KDO27607.1 - 0.41 10.5 4.2 1.1 9.1 0.4 2.7 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Prok-RING_4 PF14447.6 KDO27607.1 - 0.93 9.4 13.1 4.9 7.1 0.7 3.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf_UBZ PF18439.1 KDO27607.1 - 2.3 7.9 10.5 0.85 9.3 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 KDO27607.1 - 9.3 5.9 7.1 12 5.5 0.4 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding Ricin_B_lectin PF00652.22 KDO27608.1 - 3e-17 63.0 4.5 3.4e-07 30.6 3.0 3.3 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO27608.1 - 2.1e-08 34.7 5.0 0.047 14.4 0.3 4.1 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like E1-E2_ATPase PF00122.20 KDO27609.1 - 2e-30 105.6 2.0 2e-30 105.6 2.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KDO27609.1 - 4.5e-09 36.9 0.0 1.7e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KDO27609.1 - 7.9e-06 26.0 0.9 1.9e-05 24.8 0.3 1.8 1 1 1 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 KDO27609.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) TraP PF07296.11 KDO27609.1 - 0.066 12.4 0.1 0.15 11.2 0.1 1.7 1 0 0 1 1 1 0 TraP protein DUF1298 PF06974.13 KDO27610.1 - 3.6e-26 91.8 0.0 6.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KDO27610.1 - 2.1e-09 37.6 1.9 2e-06 27.8 1.9 2.3 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KDO27610.1 - 6.6e-05 21.8 0.2 0.00014 20.7 0.1 1.5 2 0 0 2 2 2 1 Condensation domain Ribosomal_L13e PF01294.18 KDO27611.1 - 0.028 14.3 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e HIGH_NTase1_ass PF16581.5 KDO27611.1 - 0.23 11.4 0.0 0.33 10.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region DUF1295 PF06966.12 KDO27613.1 - 1.9e-59 201.0 0.9 2.1e-59 200.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KDO27613.1 - 3e-08 33.8 2.5 1.6e-07 31.4 0.5 2.6 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KDO27613.1 - 0.0014 19.0 0.2 0.0041 17.5 0.2 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KDO27613.1 - 0.034 14.5 0.2 0.11 12.9 0.2 1.9 1 0 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KDO27613.1 - 0.081 11.7 0.0 0.24 10.1 0.0 1.8 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family CPP1-like PF11833.8 KDO27613.1 - 5.2 6.7 7.1 0.21 11.2 0.9 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1295 PF06966.12 KDO27614.1 - 2.4e-56 190.9 3.0 3.1e-56 190.5 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KDO27614.1 - 1e-08 35.3 0.6 6.3e-08 32.7 0.6 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KDO27614.1 - 4.5e-06 25.7 0.2 1.4e-05 24.0 0.2 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KDO27614.1 - 9.8e-06 25.9 0.0 3.7e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KDO27614.1 - 0.00023 21.5 0.3 0.00023 21.5 0.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase Cuticle_3 PF11018.8 KDO27615.1 - 0.19 11.9 41.1 12 6.1 41.3 2.6 1 1 1 2 2 2 0 Pupal cuticle protein C1 SOG2 PF10428.9 KDO27616.1 - 1.8 7.7 4.3 2.3 7.3 4.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MIT PF04212.18 KDO27617.1 - 0.17 11.9 1.4 0.22 11.6 1.0 1.3 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain OST3_OST6 PF04756.13 KDO27618.1 - 9.3e-64 215.6 0.0 1.1e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Copper-fist PF00649.18 KDO27618.1 - 0.083 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain WD40 PF00400.32 KDO27619.1 - 6.8e-11 42.6 4.3 0.013 16.3 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 KDO27619.1 - 0.0012 17.6 0.4 0.006 15.3 0.1 1.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 EGF PF00008.27 KDO27621.1 - 4e-05 23.8 7.2 4e-05 23.8 7.2 3.8 3 1 0 3 3 3 1 EGF-like domain EGF_2 PF07974.13 KDO27621.1 - 0.0041 17.5 15.0 0.0041 17.5 15.0 4.8 5 1 0 5 5 5 2 EGF-like domain Chordopox_A13L PF05961.11 KDO27621.1 - 0.0045 17.2 0.2 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Pox_A14 PF05767.12 KDO27621.1 - 0.0083 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 YajC PF02699.15 KDO27621.1 - 0.11 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF1180 PF06679.12 KDO27621.1 - 0.12 12.8 6.7 0.15 12.5 4.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Syndecan PF01034.20 KDO27621.1 - 1.4 8.9 3.4 2.7 8.0 3.4 1.3 1 0 0 1 1 1 0 Syndecan domain ORC6 PF05460.13 KDO27621.1 - 2.3 7.4 6.8 2.8 7.1 6.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) EGF_2 PF07974.13 KDO27622.1 - 0.00065 20.0 17.1 0.00065 20.0 17.1 4.5 4 1 2 6 6 4 2 EGF-like domain DUF4381 PF14316.6 KDO27622.1 - 0.002 18.4 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF4051 PF13260.6 KDO27622.1 - 0.0082 15.9 2.4 0.016 14.9 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) Endomucin PF07010.12 KDO27622.1 - 0.013 15.5 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 Endomucin BatD PF13584.6 KDO27622.1 - 0.016 14.1 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Phage_holin_3_6 PF07332.11 KDO27622.1 - 0.017 15.2 0.2 0.017 15.2 0.2 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3382 PF11862.8 KDO27622.1 - 0.043 14.1 0.2 0.043 14.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) TMEM154 PF15102.6 KDO27622.1 - 0.048 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family NfeD PF01957.18 KDO27622.1 - 0.067 13.6 0.0 2.8 8.4 0.0 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4307 PF14155.6 KDO27622.1 - 0.074 12.9 0.2 0.074 12.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Wzz PF02706.15 KDO27622.1 - 0.079 13.3 1.1 0.16 12.3 1.1 1.4 1 0 0 1 1 1 0 Chain length determinant protein DUF3290 PF11694.8 KDO27622.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF5385 PF17359.2 KDO27622.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) LRR_6 PF13516.6 KDO27623.1 - 0.00078 19.3 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat polyprenyl_synt PF00348.17 KDO27624.1 - 3.8e-60 203.1 0.0 4.7e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3263 PF11662.8 KDO27624.1 - 0.16 11.9 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Glyco_hydro_63 PF03200.16 KDO27625.1 - 5.5e-148 493.8 0.0 3.7e-96 322.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KDO27625.1 - 1.2e-33 117.2 0.1 1.2e-33 117.2 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 KDO27625.1 - 0.00013 21.1 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase ubiquitin PF00240.23 KDO27627.1 - 1.9e-12 46.8 0.0 3.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 KDO27627.1 - 4.3e-05 23.9 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KDO27627.1 - 0.026 14.5 0.1 12 5.9 0.0 3.2 3 0 0 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain Myb_DNA-binding PF00249.31 KDO27628.1 - 1.7e-20 72.9 7.6 5.6e-10 39.3 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO27628.1 - 1e-15 57.7 0.1 1.1e-07 32.0 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO27628.1 - 0.00061 20.1 6.2 0.0044 17.4 0.5 2.4 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain DUF4404 PF14357.6 KDO27628.1 - 0.2 12.3 0.1 1.1 10.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) BT1 PF03092.16 KDO27629.1 - 9.6e-17 60.4 1.6 9.6e-17 60.4 1.6 2.6 2 1 0 2 2 2 1 BT1 family MFS_1 PF07690.16 KDO27629.1 - 9.7e-06 24.7 32.0 9.7e-06 24.7 32.0 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily ArAE_2 PF10334.9 KDO27631.1 - 0.025 14.4 0.2 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 ADIP PF11559.8 KDO27631.1 - 0.089 12.9 11.6 1.4 9.0 12.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF29 PF01724.16 KDO27631.1 - 0.1 12.8 1.8 0.17 12.1 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 ELFV_dehydrog PF00208.21 KDO27632.1 - 8.9e-34 117.3 0.0 1.6e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KDO27632.1 - 1.5e-20 72.5 3.4 1e-17 63.1 1.2 3.6 3 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KDO27632.1 - 0.0014 18.5 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SHIPPO-rpt PF07004.12 KDO27633.1 - 4.4e-18 65.3 28.8 0.052 14.5 0.3 9.9 9 0 0 9 9 9 9 Sperm-tail PG-rich repeat Pkinase PF00069.25 KDO27634.1 - 3.2e-46 157.8 0.0 4.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27634.1 - 7.6e-29 100.8 0.0 1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO27634.1 - 3.1e-06 27.3 0.6 0.0041 17.1 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO27634.1 - 0.00066 19.1 0.0 0.005 16.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO27634.1 - 0.0065 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KDO27634.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO27634.1 - 0.042 12.8 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KDO27635.1 - 2.1e-50 171.6 0.0 2.6e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27635.1 - 6.6e-26 91.1 0.0 9.2e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO27635.1 - 0.0022 17.4 0.1 0.0049 16.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO27635.1 - 0.0047 16.9 0.4 0.012 15.6 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KDO27635.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KDO27635.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KDO27636.1 - 3.1e-38 131.7 0.0 3.8e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27636.1 - 1.9e-21 76.5 0.0 2.3e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27636.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KDO27637.1 - 1e-48 166.0 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27637.1 - 7.3e-24 84.4 0.0 1.5e-23 83.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO27637.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO27637.1 - 0.096 12.6 1.8 0.14 12.1 0.3 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 KDO27638.1 - 3.1e-27 95.0 11.6 2.4e-12 47.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27638.1 - 9.1e-23 80.3 5.0 3.8e-08 33.7 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27638.1 - 4.7e-21 72.6 9.6 7.2e-05 22.9 0.1 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KDO27638.1 - 2e-20 72.6 13.1 2.3e-08 34.2 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO27638.1 - 2.4e-16 59.4 22.1 0.00014 22.1 0.1 6.3 7 1 0 7 7 7 5 Ankyrin repeat CMD PF02627.20 KDO27638.1 - 0.3 11.2 8.3 0.46 10.6 1.6 2.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Ion_trans PF00520.31 KDO27639.1 - 3.5e-06 26.4 11.0 5.7e-06 25.7 11.0 1.2 1 0 0 1 1 1 1 Ion transport protein M_domain PF12938.7 KDO27639.1 - 0.064 13.1 2.4 0.13 12.0 2.4 1.5 1 0 0 1 1 1 0 M domain of GW182 AAA_18 PF13238.6 KDO27640.1 - 2.5e-05 24.9 0.2 0.00011 22.7 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KDO27640.1 - 0.00026 21.0 0.4 0.0012 18.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO27640.1 - 0.00056 20.1 1.5 0.0035 17.5 1.5 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KDO27640.1 - 0.0013 18.1 0.0 0.0039 16.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KDO27640.1 - 0.0017 18.3 0.3 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KDO27640.1 - 0.006 17.0 0.2 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KDO27640.1 - 0.0088 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KDO27640.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 KDO27640.1 - 0.012 15.2 0.1 0.049 13.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO27640.1 - 0.021 15.2 0.2 0.16 12.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KDO27640.1 - 0.029 14.1 0.7 0.073 12.8 0.7 1.8 1 1 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 KDO27640.1 - 0.031 14.8 0.2 0.11 13.1 0.2 2.0 1 1 0 1 1 1 0 ABC transporter SKI PF01202.22 KDO27640.1 - 0.034 14.3 0.3 5 7.2 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 KDO27640.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 KDO27640.1 - 0.076 13.1 1.2 0.18 11.8 1.2 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 KDO27640.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KDO27640.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF4658 PF15555.6 KDO27641.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) DSHCT PF08148.12 KDO27642.1 - 6.3e-54 182.1 0.4 1.9e-53 180.5 0.3 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KDO27642.1 - 4.1e-20 72.8 0.0 6e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KDO27642.1 - 3.3e-17 62.8 0.0 7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ski2_N PF17911.1 KDO27642.1 - 5.3e-08 32.8 0.1 1.5e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region Helicase_C PF00271.31 KDO27642.1 - 2.5e-06 27.8 0.0 5.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO27642.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KDO27642.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KDO27642.1 - 0.029 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KDO27642.1 - 0.062 13.0 0.0 7.4 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain LapA_dom PF06305.11 KDO27643.1 - 0.0014 18.4 0.3 0.0023 17.7 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Tad PF13400.6 KDO27643.1 - 0.0044 17.3 0.6 0.009 16.3 0.6 1.5 1 0 0 1 1 1 1 Putative Flp pilus-assembly TadE/G-like TNFR_16_TM PF18422.1 KDO27643.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Peptidase_S8 PF00082.22 KDO27644.1 - 8.5e-41 140.1 0.7 8.5e-41 140.1 0.7 1.6 2 0 0 2 2 2 1 Subtilase family zf-H2C2_5 PF13909.6 KDO27644.1 - 0.011 15.4 0.0 0.045 13.5 0.0 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain ECR1_N PF14382.6 KDO27644.1 - 0.014 15.2 0.2 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region DUF2754 PF10953.8 KDO27644.1 - 0.19 12.0 0.3 0.38 11.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Ank_4 PF13637.6 KDO27646.1 - 0.022 15.3 1.1 6.7 7.4 0.2 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) FA_desaturase PF00487.24 KDO27648.1 - 9.7e-34 117.3 17.7 1.3e-33 116.9 17.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KDO27648.1 - 2.9e-17 62.6 0.2 5.4e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_24 PF18404.1 KDO27649.1 - 1.5e-137 457.4 3.1 2.1e-137 456.9 3.1 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_12 PF18400.1 KDO27649.1 - 1.4e-29 103.4 0.1 1.2e-28 100.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KDO27649.1 - 2.2e-27 96.6 0.0 6.7e-24 85.2 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KDO27649.1 - 1.9e-23 82.6 0.0 3.5e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KDO27649.1 - 3.6e-15 56.1 2.4 1.7e-14 53.9 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KDO27649.1 - 3.6e-12 46.7 0.1 9.8e-11 42.0 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KDO27649.1 - 7.6e-06 25.7 0.3 1.4e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 LPMO_10 PF03067.15 KDO27650.1 - 1.6e-22 81.2 0.1 2.1e-22 80.7 0.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 KDO27651.1 - 7.6e-23 82.2 0.3 1e-22 81.7 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 KDO27652.1 - 8.7e-20 72.2 0.0 1.7e-19 71.2 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_19 PF00182.19 KDO27653.1 - 8.1e-13 48.8 1.4 1.5e-11 44.7 1.4 2.0 1 1 0 1 1 1 1 Chitinase class I CBM_1 PF00734.18 KDO27653.1 - 0.00036 20.4 1.7 0.00036 20.4 1.7 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_19 PF00182.19 KDO27655.1 - 8.9e-45 153.4 5.3 1.2e-42 146.5 5.3 3.1 1 1 0 1 1 1 1 Chitinase class I CBM_1 PF00734.18 KDO27655.1 - 1.2e-11 44.3 13.1 4e-10 39.5 6.3 2.9 2 0 0 2 2 2 2 Fungal cellulose binding domain PT PF04886.12 KDO27655.1 - 7e-08 31.9 44.6 4.3e-05 22.9 22.1 4.1 4 1 0 4 4 4 2 PT repeat Aa_trans PF01490.18 KDO27656.1 - 1.4e-14 53.7 22.2 2e-14 53.2 22.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_8 PF13855.6 KDO27657.1 - 2.1e-29 101.0 32.9 3.3e-11 42.8 3.0 5.9 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 KDO27657.1 - 7.1e-27 93.0 26.8 2.5e-05 24.5 2.0 7.6 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO27657.1 - 2.7e-06 27.0 12.6 0.0057 16.2 1.1 3.3 1 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KDO27657.1 - 3.4e-06 27.0 0.1 0.085 12.8 0.1 3.2 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KDO27657.1 - 5e-05 23.3 18.3 6 7.8 1.5 8.4 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO27657.1 - 0.0098 15.9 22.7 1.7 8.9 0.2 7.8 8 0 0 8 8 8 2 Leucine Rich repeat CREPT PF16566.5 KDO27657.1 - 0.12 12.6 3.2 12 6.1 0.1 3.2 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Ank_2 PF12796.7 KDO27659.1 - 1.1e-25 90.0 5.3 1.3e-15 57.7 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27659.1 - 9.6e-21 73.9 0.1 2.3e-10 40.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27659.1 - 2.5e-12 45.8 0.2 0.011 16.2 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KDO27659.1 - 4.8e-12 45.7 0.2 0.0002 21.7 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO27659.1 - 4.8e-11 42.7 0.2 2.3e-06 27.8 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 KDO27659.1 - 0.0053 17.2 0.9 0.027 14.9 0.9 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO27659.1 - 0.014 16.2 1.7 0.057 14.3 0.9 2.6 2 0 0 2 2 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KDO27659.1 - 0.026 14.5 0.5 0.06 13.4 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger HTH_1 PF00126.27 KDO27659.1 - 0.069 13.1 0.1 2.8 7.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF2156 PF09924.9 KDO27659.1 - 0.097 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Strep_SA_rep PF06696.11 KDO27659.1 - 0.71 9.9 7.6 2.5 8.2 0.0 3.5 4 0 0 4 4 4 0 Streptococcal surface antigen repeat Cnn_1N PF07989.11 KDO27659.1 - 1 9.6 3.9 2.1 8.6 0.8 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-BED PF02892.15 KDO27659.1 - 2 8.5 4.9 5.2 7.2 0.1 3.2 3 0 0 3 3 3 0 BED zinc finger Ras PF00071.22 KDO27660.1 - 4.4e-12 45.9 0.0 5.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO27660.1 - 6.9e-09 36.0 0.0 8.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO27660.1 - 2.5e-06 27.1 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO27660.1 - 0.0046 17.0 0.0 0.0067 16.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO27660.1 - 0.0063 15.9 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KDO27660.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KDO27660.1 - 0.12 11.9 0.0 0.47 10.0 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 KDO27660.1 - 0.22 11.2 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KDO27661.1 - 4.1e-05 24.3 7.5 0.17 12.8 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DnaJ PF00226.31 KDO27662.1 - 1.4e-14 53.9 0.1 3.8e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 KDO27662.1 - 5.9e-10 38.5 4.0 8.7e-06 25.3 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27662.1 - 2.7e-05 24.0 15.1 0.00057 19.8 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO27662.1 - 0.00069 19.2 0.6 0.01 15.5 0.4 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 KDO27662.1 - 0.0011 19.2 0.5 2 9.0 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat GrpE PF01025.19 KDO27662.1 - 0.0044 16.7 8.0 0.0044 16.7 8.0 3.0 3 1 0 3 3 3 1 GrpE DUF2277 PF10041.9 KDO27662.1 - 0.028 14.8 0.0 0.028 14.8 0.0 3.9 3 2 1 4 4 4 0 Uncharacterized conserved protein (DUF2277) TPR_16 PF13432.6 KDO27662.1 - 0.15 12.7 0.3 0.15 12.7 0.3 3.6 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27662.1 - 2.9 8.9 11.5 18 6.5 0.5 4.5 2 1 2 4 4 4 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 KDO27663.1 - 4.2e-38 129.6 17.0 7.7e-16 58.3 0.4 5.2 5 1 1 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 KDO27663.1 - 3.4e-37 123.2 22.8 1.3e-07 30.6 0.8 7.3 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 KDO27663.1 - 3.4e-29 98.2 16.3 5.1e-06 26.0 0.1 6.8 7 0 0 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 KDO27663.1 - 2.9e-26 91.1 19.9 1.2e-08 34.6 0.6 6.4 4 2 2 6 6 6 6 EF-hand domain pair EF-hand_5 PF13202.6 KDO27663.1 - 3.5e-24 83.2 15.6 1.5e-05 24.3 0.3 6.5 6 0 0 6 6 6 6 EF hand EF-hand_9 PF14658.6 KDO27663.1 - 2.5e-10 40.5 0.4 0.017 15.5 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain C2 PF00168.30 KDO27663.1 - 1.2e-08 35.1 0.0 7.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 C2 domain SPARC_Ca_bdg PF10591.9 KDO27663.1 - 6.2e-08 33.0 6.0 0.16 12.3 0.0 3.9 4 0 0 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO27663.1 - 1.8e-07 31.1 4.6 0.35 10.8 0.1 4.3 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand L27 PF02828.16 KDO27663.1 - 0.041 13.6 3.0 1.2 8.9 0.9 3.1 3 0 0 3 3 3 0 L27 domain PseudoU_synth_2 PF00849.22 KDO27664.1 - 5.6e-13 49.3 0.4 4.1e-12 46.5 0.4 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KDO27664.1 - 2.6e-10 39.8 0.3 7.6e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 KDO27664.1 - 5.3e-05 23.0 0.1 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 S4 domain DUF2052 PF09747.9 KDO27665.1 - 1.9e-33 116.3 9.3 2.5e-33 115.9 9.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) BRCT_2 PF16589.5 KDO27666.1 - 6.8e-09 36.0 0.0 0.00051 20.4 0.1 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_2 PF13923.6 KDO27666.1 - 1.1e-08 34.8 12.8 1.1e-08 34.8 12.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO27666.1 - 5.1e-08 33.1 12.8 5.1e-08 33.1 12.8 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO27666.1 - 6.6e-08 32.5 8.4 6.6e-08 32.5 8.4 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO27666.1 - 1.2e-07 31.5 10.9 1.2e-07 31.5 10.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 KDO27666.1 - 2e-07 31.3 0.1 9.3e-07 29.1 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4 PF00097.25 KDO27666.1 - 2.2e-06 27.4 13.7 2.2e-06 27.4 13.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO27666.1 - 2.6e-06 27.5 12.0 2.6e-06 27.5 12.0 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO27666.1 - 9.1e-06 25.5 11.6 9.1e-06 25.5 11.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain PTCB-BRCT PF12738.7 KDO27666.1 - 0.00023 21.1 0.3 0.00051 19.9 0.3 1.6 1 0 0 1 1 1 1 twin BRCT domain zf-RING_6 PF14835.6 KDO27666.1 - 0.00041 20.2 5.1 0.00097 19.0 5.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KDO27666.1 - 0.0037 17.1 12.0 0.0037 17.1 12.0 2.8 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 RTT107_BRCT_5 PF16770.5 KDO27666.1 - 0.012 15.4 0.1 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-Nse PF11789.8 KDO27666.1 - 0.02 14.7 7.8 0.046 13.6 7.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DNA_ligase_ZBD PF03119.16 KDO27666.1 - 0.026 14.6 2.2 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain GAGA PF09237.11 KDO27666.1 - 0.22 11.4 1.3 0.69 9.8 0.1 2.3 2 0 0 2 2 2 0 GAGA factor zf-RING_10 PF16685.5 KDO27666.1 - 0.24 11.6 10.3 0.29 11.3 7.4 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KDO27666.1 - 0.46 10.8 16.7 0.22 11.8 11.5 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KDO27666.1 - 0.76 9.5 9.2 0.15 11.7 3.1 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 KDO27666.1 - 3.7 7.4 13.5 2.3 8.0 9.9 2.5 2 0 0 2 2 2 0 RING-like zinc finger Aldo_ket_red PF00248.21 KDO27667.1 - 0.00016 21.0 0.0 0.0013 18.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family AA_kinase PF00696.28 KDO27668.1 - 0.15 11.7 0.0 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 Amino acid kinase family RabGAP-TBC PF00566.18 KDO27669.1 - 1.2e-37 129.7 0.0 1.9e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WWE PF02825.20 KDO27669.1 - 0.00042 20.9 0.1 0.0029 18.2 0.1 2.2 2 0 0 2 2 2 1 WWE domain AKAP7_NLS PF10469.9 KDO27670.1 - 2.2e-20 73.4 0.0 5.3e-20 72.2 0.0 1.6 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KDO27670.1 - 1.5e-06 28.2 0.6 2.7e-06 27.4 0.6 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AAA_18 PF13238.6 KDO27670.1 - 2.3e-06 28.2 0.0 4.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO27670.1 - 4e-06 27.1 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO27670.1 - 6.3e-05 23.2 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO27670.1 - 0.00034 21.0 1.6 0.0011 19.4 0.1 2.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KDO27670.1 - 0.0013 18.8 0.0 0.0059 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KDO27670.1 - 0.0013 18.0 0.0 0.0041 16.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KDO27670.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KDO27670.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 KDO27670.1 - 0.0037 17.1 0.4 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 KDO27670.1 - 0.0048 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KDO27670.1 - 0.0063 16.4 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 KDO27670.1 - 0.0064 15.8 0.1 0.022 14.1 0.1 1.8 1 1 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 KDO27670.1 - 0.014 15.9 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 KDO27670.1 - 0.056 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KDO27670.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KDO27670.1 - 0.086 12.5 0.0 0.88 9.2 0.0 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KDO27670.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.7 1 1 1 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KDO27670.1 - 0.12 11.5 0.1 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KDO27670.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KDO27670.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO27670.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KDO27670.1 - 0.2 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Ank_2 PF12796.7 KDO27671.1 - 1.6e-11 44.6 2.1 3.7e-06 27.4 0.0 5.1 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO27671.1 - 2.9e-09 36.4 0.7 0.15 12.7 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KDO27671.1 - 4.6e-06 26.8 2.6 0.14 12.7 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KDO27671.1 - 4.7e-06 26.8 5.6 0.17 12.2 0.1 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO27671.1 - 0.00015 22.2 4.1 0.061 13.9 0.2 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) ZZ PF00569.17 KDO27672.1 - 4.4e-10 39.2 4.1 8.3e-10 38.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PRIMA1 PF16101.5 KDO27672.1 - 0.093 12.8 3.5 0.37 10.8 0.4 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FliD_N PF02465.18 KDO27672.1 - 0.46 11.2 8.4 1.6 9.4 0.5 2.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Baculo_IE-1 PF05290.11 KDO27672.1 - 0.61 10.0 2.6 0.64 10.0 1.0 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF16 PF01519.16 KDO27672.1 - 1.3 9.6 14.2 4.4 7.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Csm1_N PF18504.1 KDO27672.1 - 1.9 8.9 26.3 0.071 13.5 3.5 4.7 2 2 1 4 4 4 0 Csm1 N-terminal domain Aldose_epim PF01263.20 KDO27673.1 - 9.5e-39 133.5 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2345 PF10106.9 KDO27673.1 - 0.048 13.5 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Ank_2 PF12796.7 KDO27674.1 - 7.5e-10 39.3 3.6 1.6e-05 25.4 4.4 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27674.1 - 2.7e-05 24.6 10.1 0.074 13.7 0.9 4.8 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27674.1 - 0.0022 18.4 11.4 2.5 9.0 0.3 5.9 5 1 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KDO27674.1 - 0.042 14.2 12.1 0.18 12.2 0.2 4.5 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 KDO27674.1 - 0.78 10.3 8.8 24 5.6 0.1 4.4 2 1 1 3 3 3 0 Ankyrin repeat Myb_DNA-binding PF00249.31 KDO27675.1 - 1.3e-29 102.1 6.8 3.4e-14 52.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO27675.1 - 1.5e-20 73.2 5.6 4e-16 59.0 1.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO27675.1 - 0.00077 19.3 0.1 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KDO27675.1 - 0.0017 18.7 3.0 0.0037 17.6 0.4 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KDO27675.1 - 0.01 16.0 1.3 0.028 14.6 0.3 2.0 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KDO27675.1 - 0.013 15.5 0.1 0.051 13.6 0.0 2.0 2 0 0 2 2 2 0 SLIDE DUF3721 PF12518.8 KDO27675.1 - 0.21 11.4 0.7 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function Myb_DNA-bind_5 PF13873.6 KDO27675.1 - 1.2 9.2 4.8 0.78 9.9 0.2 2.6 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Spc7 PF08317.11 KDO27677.1 - 0.0043 16.0 10.4 0.0043 16.0 10.4 4.4 1 1 4 5 5 5 4 Spc7 kinetochore protein XhlA PF10779.9 KDO27677.1 - 1.3 9.3 20.2 1.4 9.2 1.0 5.8 6 0 0 6 6 6 0 Haemolysin XhlA FlaC_arch PF05377.11 KDO27677.1 - 2 8.8 10.7 49 4.4 0.1 5.7 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 KDO27677.1 - 3 7.8 0.0 3 7.8 0.0 7.4 8 2 1 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Occludin_ELL PF07303.13 KDO27677.1 - 9.8 7.0 26.8 4.8 8.0 0.3 5.9 4 1 2 6 6 6 0 Occludin homology domain MIF4G_like_2 PF09090.11 KDO27678.1 - 9.2e-25 87.6 3.5 3.3e-24 85.8 3.5 1.8 1 1 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KDO27678.1 - 6.9e-17 61.8 0.8 2.6e-16 60.0 0.8 1.9 1 1 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KDO27678.1 - 0.00096 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain UPF0004 PF00919.20 KDO27678.1 - 0.027 14.5 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 PDZ_6 PF17820.1 KDO27679.1 - 5.7e-12 45.3 0.1 4.9e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KDO27679.1 - 4.4e-09 36.6 0.2 0.0014 18.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain MPP6 PF10175.9 KDO27680.1 - 1.3e-13 51.6 6.4 1.3e-13 51.6 6.4 1.9 2 1 0 2 2 2 1 M-phase phosphoprotein 6 PIN_12 PF16289.5 KDO27681.1 - 4.2 7.8 8.0 7.6 7.0 7.4 1.8 1 1 0 1 1 1 0 PIN domain HSF_DNA-bind PF00447.17 KDO27682.1 - 2.5e-23 82.5 0.0 4.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Radical_SAM_C PF16199.5 KDO27683.1 - 3e-33 113.7 0.1 1.5e-32 111.5 0.0 2.2 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KDO27683.1 - 4.4e-17 63.0 0.8 3.4e-16 60.1 0.2 2.6 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KDO27683.1 - 8.4e-10 38.9 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO27683.1 - 2.6e-06 27.4 0.0 1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO27683.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO27683.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Piezo_RRas_bdg PF12166.8 KDO27684.1 - 1.6e-77 261.6 0.0 2.6e-77 260.9 0.0 1.4 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain fn3 PF00041.21 KDO27684.1 - 2.7e-11 43.7 0.0 6.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain EF-hand_1 PF00036.32 KDO27685.1 - 1.1e-19 68.5 5.8 2.1e-06 26.9 0.3 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO27685.1 - 1.3e-17 62.2 2.2 3.6e-07 29.6 0.0 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KDO27685.1 - 2.6e-15 56.6 3.0 6.3e-10 39.4 0.4 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO27685.1 - 6.4e-15 54.7 5.9 1.3e-08 34.5 0.1 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO27685.1 - 3e-13 48.6 5.3 0.00035 19.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KDO27685.1 - 5.3e-08 33.1 0.2 4.5e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KDO27685.1 - 0.037 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF4649 PF15507.6 KDO27685.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4649) FGAR-AT_linker PF18072.1 KDO27685.1 - 0.13 12.9 0.0 1.9 9.1 0.0 2.7 3 1 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_2 PF09068.11 KDO27685.1 - 0.15 12.3 0.0 20 5.4 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_11 PF08976.11 KDO27685.1 - 0.15 13.0 0.4 0.7 10.8 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain WD40 PF00400.32 KDO27686.1 - 4.4e-12 46.3 3.5 0.035 15.0 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27686.1 - 0.032 14.5 0.2 4 7.8 0.0 4.1 4 2 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KDO27686.1 - 0.11 12.4 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal VPS9 PF02204.18 KDO27687.1 - 6.2e-18 64.9 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain FSH1 PF03959.13 KDO27688.1 - 1.4e-49 168.7 0.0 1.7e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KDO27688.1 - 2.2e-05 24.3 0.2 0.081 12.6 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KDO27688.1 - 0.0068 16.2 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase CPSase_sm_chain PF00988.22 KDO27688.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Hydrolase_4 PF12146.8 KDO27688.1 - 0.018 14.3 0.1 3.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO27688.1 - 0.022 15.4 2.0 0.06 13.9 2.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KDO27688.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 KDO27688.1 - 0.049 13.5 0.0 0.17 11.7 0.0 2.0 2 1 0 2 2 2 0 Palmitoyl protein thioesterase BAAT_C PF08840.11 KDO27688.1 - 0.063 13.2 0.1 0.52 10.2 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Asparaginase PF00710.20 KDO27689.1 - 4.6e-16 58.9 0.0 6.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal DSPc PF00782.20 KDO27689.1 - 3.5e-06 26.9 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RCDG1 PF15725.5 KDO27689.1 - 0.032 14.7 0.9 0.075 13.5 0.9 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Y_phosphatase PF00102.27 KDO27689.1 - 0.04 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ank_2 PF12796.7 KDO27690.1 - 5.3e-23 81.4 0.3 2.2e-11 44.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27690.1 - 2.1e-21 76.0 2.0 1.2e-12 48.0 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO27690.1 - 2.2e-21 75.3 1.6 2.1e-05 24.8 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KDO27690.1 - 2.9e-18 65.7 1.0 1.7e-06 28.2 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27690.1 - 4e-18 63.6 0.2 0.00017 21.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat AnkUBD PF18418.1 KDO27690.1 - 0.11 12.6 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain Alg6_Alg8 PF03155.15 KDO27691.1 - 2.2e-158 528.3 20.9 2.5e-158 528.0 20.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family LapA_dom PF06305.11 KDO27691.1 - 0.11 12.3 0.1 0.11 12.3 0.1 4.4 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain AhpC-TSA PF00578.21 KDO27692.1 - 4.9e-35 120.1 0.1 9.5e-35 119.2 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KDO27692.1 - 3.4e-14 52.8 0.0 4.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KDO27692.1 - 9e-11 41.4 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KDO27692.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC LETM1 PF07766.13 KDO27693.1 - 2.9e-40 138.3 0.1 5.9e-40 137.3 0.1 1.5 1 1 0 1 1 1 1 LETM1-like protein TMP-TENI PF02581.17 KDO27694.1 - 2.8e-23 82.2 0.0 3.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase NMO PF03060.15 KDO27694.1 - 0.00062 19.3 0.4 0.0012 18.3 0.4 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KDO27694.1 - 0.0013 18.0 0.1 0.017 14.4 0.0 2.0 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase HEAT PF02985.22 KDO27695.1 - 1.4e-07 31.2 4.2 0.017 15.3 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat PDZ_6 PF17820.1 KDO27695.1 - 0.00016 21.5 0.0 0.7 9.8 0.0 2.7 2 0 0 2 2 2 2 PDZ domain HEAT_2 PF13646.6 KDO27695.1 - 0.0065 16.8 0.7 3.5 8.1 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats UME PF08064.13 KDO27695.1 - 0.029 14.3 1.0 1.8 8.5 0.5 2.7 2 0 0 2 2 2 0 UME (NUC010) domain PDZ_2 PF13180.6 KDO27695.1 - 0.097 13.0 0.0 7.8 6.9 0.0 2.4 2 0 0 2 2 2 0 PDZ domain UCR_14kD PF02271.16 KDO27696.1 - 5.9e-22 77.5 0.5 6.4e-22 77.4 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Choline_transpo PF04515.12 KDO27698.1 - 4.6e-30 104.9 22.8 1.4e-29 103.4 22.7 1.8 1 1 0 1 1 1 1 Plasma-membrane choline transporter Chi-conotoxin PF16981.5 KDO27699.1 - 0.0077 16.4 0.1 0.024 14.9 0.1 1.8 1 0 0 1 1 1 1 chi-Conotoxin or t superfamily CUE PF02845.16 KDO27699.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 CUE domain Ribosomal_L22e PF01776.17 KDO27700.1 - 4.8e-47 158.9 2.9 5.8e-47 158.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Ras PF00071.22 KDO27701.1 - 3.5e-39 134.0 0.0 4.3e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO27701.1 - 7.3e-27 94.0 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO27701.1 - 4e-09 36.2 0.1 4.9e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO27701.1 - 0.0026 17.2 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region XFP_N PF09364.10 KDO27701.1 - 0.045 12.5 0.0 3.6 6.3 0.0 2.1 1 1 1 2 2 2 0 XFP N-terminal domain UDPGP PF01704.18 KDO27702.1 - 2.4e-123 411.8 0.0 3.3e-123 411.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 KDO27702.1 - 9.4e-30 103.1 0.0 1.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KDO27702.1 - 2.1e-08 34.7 0.4 6.9e-08 33.0 0.4 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KDO27703.1 - 5.4e-22 78.1 0.0 9.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KDO27703.1 - 2.2e-05 24.5 0.0 5.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4207 PF13904.6 KDO27704.1 - 0.0058 16.4 24.4 0.0058 16.4 24.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) Aldedh PF00171.22 KDO27704.1 - 2.4 6.6 8.0 4.4 5.7 8.0 1.4 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ion_trans PF00520.31 KDO27705.1 - 1.1e-24 87.0 19.0 2.2e-24 86.1 19.0 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO27705.1 - 7.2e-13 48.4 0.0 2.3e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO27705.1 - 5.2e-12 45.6 8.4 1.1e-11 44.5 8.4 1.6 1 0 0 1 1 1 1 Ion channel UPF0158 PF03682.13 KDO27705.1 - 0.038 14.0 0.5 9.1 6.2 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0158) IRK PF01007.20 KDO27705.1 - 2.3 8.0 11.1 0.088 12.6 4.5 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Ion_trans PF00520.31 KDO27706.1 - 4.9e-22 78.4 17.7 7.1e-22 77.8 17.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO27706.1 - 6e-13 48.7 0.1 2e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO27706.1 - 9.3e-11 41.5 7.1 9.3e-11 41.5 7.1 2.2 2 0 0 2 2 2 1 Ion channel Snapin_Pallidin PF14712.6 KDO27707.1 - 0.0055 17.1 0.3 0.017 15.6 0.3 1.8 1 0 0 1 1 1 1 Snapin/Pallidin DUF573 PF04504.14 KDO27707.1 - 0.034 14.8 1.7 0.38 11.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF573 YojJ PF10372.9 KDO27707.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Fer2 PF00111.27 KDO27708.1 - 1.1e-09 38.1 2.1 1.7e-09 37.5 2.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rad51 PF08423.11 KDO27709.1 - 1.5e-95 319.3 0.0 1.9e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KDO27709.1 - 3.4e-06 26.7 0.1 5.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KDO27709.1 - 0.00017 21.2 0.1 0.0003 20.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KDO27709.1 - 0.00023 21.7 0.4 0.00053 20.5 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KDO27709.1 - 0.00065 19.1 0.6 0.0018 17.7 0.6 1.9 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 KDO27709.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain HhH-GPD PF00730.25 KDO27709.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KDO27709.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M41 PF01434.18 KDO27710.1 - 1.8e-63 213.8 0.1 3.3e-63 213.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KDO27710.1 - 2.2e-44 151.1 0.1 2e-42 144.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO27710.1 - 1.1e-08 34.8 0.0 4.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KDO27710.1 - 3.8e-05 23.7 0.0 0.00013 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO27710.1 - 5.4e-05 23.6 0.1 0.0038 17.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO27710.1 - 6.9e-05 22.7 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KDO27710.1 - 0.00018 22.0 0.0 0.00062 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO27710.1 - 0.0008 19.7 0.1 0.15 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KDO27710.1 - 0.00087 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KDO27710.1 - 0.0013 19.0 0.0 0.081 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO27710.1 - 0.0037 17.0 0.0 0.0099 15.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KDO27710.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KDO27710.1 - 0.015 14.7 0.2 0.033 13.6 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KDO27710.1 - 0.033 14.3 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KDO27710.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KDO27710.1 - 0.088 12.1 0.1 0.82 9.0 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 KDO27710.1 - 0.093 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KDO27710.1 - 0.13 11.8 0.6 0.83 9.2 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO27710.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 KDO27711.1 - 1.1e-58 198.5 0.0 1.4e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 KDO27712.1 - 0.0065 17.0 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 PH domain RhoGEF PF00621.20 KDO27713.1 - 1.8e-15 57.7 0.0 2.7e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Amidohydro_1 PF01979.20 KDO27714.1 - 1.4e-18 67.3 1.8 3.4e-16 59.5 1.8 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KDO27714.1 - 3.8e-16 59.6 2.5 1e-09 38.4 0.0 2.8 1 1 1 2 2 2 2 Amidohydrolase family Ephrin_rec_like PF07699.13 KDO27716.1 - 0.00027 20.6 5.7 0.00027 20.6 5.7 49.6 31 16 20 52 52 52 34 Putative ephrin-receptor like HYLS1_C PF15311.6 KDO27716.1 - 1.1 10.0 3.9 3.4 8.5 0.7 2.9 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus EMC3_TMCO1 PF01956.16 KDO27717.1 - 1.6e-38 132.1 8.7 2.2e-38 131.7 8.7 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF543 PF04418.12 KDO27717.1 - 0.044 13.8 0.2 0.17 11.9 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF543) DUF5326 PF17260.2 KDO27717.1 - 0.073 13.2 0.5 0.073 13.2 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5326) T3SS_basalb_I PF17001.5 KDO27717.1 - 4.4 8.0 7.6 0.51 11.0 2.2 2.1 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Homeobox_KN PF05920.11 KDO27718.1 - 9.5e-18 63.8 0.3 2.9e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KDO27718.1 - 4.6e-10 39.2 0.1 8e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KDO27718.1 - 0.084 12.3 0.1 0.71 9.4 0.0 2.3 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KDO27719.1 - 2.3e-15 56.2 2.7 3e-15 55.8 0.8 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KDO27719.1 - 4.2e-10 39.3 3.6 4.2e-10 39.3 3.6 1.7 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 KDO27719.1 - 0.08 12.4 0.3 0.19 11.2 0.1 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Meth_synt_2 PF01717.18 KDO27721.1 - 1.8e-139 464.5 0.0 3.3e-135 450.5 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KDO27721.1 - 1.4e-93 313.9 0.0 7.9e-88 295.0 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain AAA PF00004.29 KDO27722.1 - 4.7e-91 302.1 0.0 1.1e-44 152.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO27722.1 - 3.9e-26 90.6 3.6 1.8e-14 53.2 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KDO27722.1 - 3.7e-13 49.5 0.0 1.8e-05 24.5 0.0 3.6 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO27722.1 - 9.6e-13 48.3 0.0 7.4e-07 29.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO27722.1 - 4.4e-11 43.2 0.0 0.00026 21.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KDO27722.1 - 3.4e-10 40.5 1.2 6.2e-05 23.4 0.2 4.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KDO27722.1 - 1.4e-07 31.9 0.8 0.005 17.1 0.0 4.1 2 2 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KDO27722.1 - 2e-07 31.3 0.0 0.019 15.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 KDO27722.1 - 2.3e-07 30.4 0.1 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KDO27722.1 - 4.8e-06 26.4 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KDO27722.1 - 7.8e-06 25.4 0.9 0.013 14.9 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KDO27722.1 - 1.8e-05 24.4 6.2 0.16 11.5 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_28 PF13521.6 KDO27722.1 - 5.3e-05 23.5 0.1 0.1 12.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KDO27722.1 - 5.6e-05 23.2 0.0 0.06 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KDO27722.1 - 6.8e-05 23.2 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 KDO27722.1 - 0.00017 21.6 0.0 0.006 16.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 KDO27722.1 - 0.00022 21.1 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO27722.1 - 0.00029 20.4 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KDO27722.1 - 0.00039 20.2 0.0 0.094 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KDO27722.1 - 0.0006 19.2 0.0 0.65 9.3 0.0 2.9 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.6 KDO27722.1 - 0.00083 19.9 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KDO27722.1 - 0.0054 16.7 1.1 0.42 10.5 0.1 3.4 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 KDO27722.1 - 0.0063 16.5 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KDO27722.1 - 0.0088 15.9 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KDO27722.1 - 0.01 15.5 0.0 0.3 10.8 0.0 2.9 2 2 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KDO27722.1 - 0.011 15.9 0.0 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO27722.1 - 0.012 14.9 0.7 1.6 7.9 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 KDO27722.1 - 0.015 15.8 0.0 0.86 10.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 KDO27722.1 - 0.015 15.0 0.7 0.059 13.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KDO27722.1 - 0.036 13.1 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KDO27722.1 - 0.047 14.0 0.4 0.62 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KDO27722.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein DUF815 PF05673.13 KDO27722.1 - 0.075 12.2 0.0 1 8.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) HEPN_SAV_6107 PF18726.1 KDO27722.1 - 0.18 12.3 4.9 2.3 8.8 0.6 2.8 2 0 0 2 2 2 0 SAV_6107-like HEPN PhoH PF02562.16 KDO27722.1 - 0.28 10.6 2.5 0.42 10.0 0.4 2.0 2 0 0 2 2 2 0 PhoH-like protein PMI_typeI PF01238.21 KDO27723.1 - 1.8e-108 363.1 0.0 2.4e-108 362.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KDO27723.1 - 0.0026 17.5 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KDO27723.1 - 0.0046 16.9 0.0 0.71 9.8 0.0 2.9 3 0 0 3 3 3 1 AraC-like ligand binding domain Spore_III_AB PF09548.10 KDO27723.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Cupin_6 PF12852.7 KDO27723.1 - 0.12 12.1 0.0 1.3 8.8 0.0 2.2 2 1 0 2 2 2 0 Cupin SLC35F PF06027.12 KDO27724.1 - 5.7e-78 262.5 18.6 7e-78 262.2 18.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KDO27724.1 - 9.7e-11 41.2 0.6 9.7e-11 41.2 0.6 2.1 2 1 1 3 3 3 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO27724.1 - 1e-10 41.9 24.4 7e-08 32.7 8.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KDO27724.1 - 9.9e-09 34.8 12.9 1.6e-08 34.1 12.9 1.3 1 1 0 1 1 1 1 UAA transporter family Mg_trans_NIPA PF05653.14 KDO27724.1 - 0.01 14.9 1.4 0.01 14.9 1.4 2.3 1 1 2 3 3 3 0 Magnesium transporter NIPA TMEM174 PF15029.6 KDO27724.1 - 0.019 14.7 0.5 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 174 Adeno_E3 PF06040.11 KDO27724.1 - 0.4 10.8 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein Ran_BP1 PF00638.18 KDO27725.1 - 2.7e-20 72.9 0.8 2.7e-20 72.9 0.8 2.3 2 1 1 3 3 3 1 RanBP1 domain Gly_reductase PF09338.11 KDO27725.1 - 0.015 13.7 0.2 0.017 13.5 0.2 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits Vps53_N PF04100.12 KDO27726.1 - 5e-96 322.0 3.6 8.1e-96 321.3 3.6 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KDO27726.1 - 1.1e-08 34.7 5.4 2.4e-08 33.6 5.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 KDO27726.1 - 6.5e-07 28.0 7.5 9.1e-05 20.9 0.1 2.6 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) RINT1_TIP1 PF04437.13 KDO27726.1 - 0.0025 16.8 0.7 0.036 12.9 0.0 2.7 3 0 0 3 3 3 1 RINT-1 / TIP-1 family DUF5588 PF17826.1 KDO27726.1 - 0.0046 15.9 0.5 1.8 7.3 0.1 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5588) VPS53_C PF16854.5 KDO27726.1 - 0.015 15.2 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus Sec8_exocyst PF04048.14 KDO27726.1 - 0.032 14.1 1.3 0.13 12.2 1.3 2.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 KDO27726.1 - 0.13 12.4 4.7 0.11 12.7 1.9 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4523 PF15023.6 KDO27726.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) COG2 PF06148.11 KDO27726.1 - 0.96 9.5 5.9 7.8 6.6 3.8 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KDO27726.1 - 3.2 7.8 9.0 21 5.2 0.4 4.4 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynactin_p22 PF07426.11 KDO27726.1 - 4.8 7.0 9.0 2.1 8.2 5.8 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 RTT107_BRCT_5 PF16770.5 KDO27727.1 - 2.2e-07 30.7 0.0 1.3e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KDO27727.1 - 0.00023 21.5 0.0 0.0024 18.2 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KDO27728.1 - 2.1e-05 24.3 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KDO27728.1 - 0.00061 20.1 0.0 0.74 10.2 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KDO27728.1 - 0.0024 18.3 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain TFIIA PF03153.13 KDO27729.1 - 0.052 13.5 7.1 0.069 13.1 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Filo_VP35 PF02097.15 KDO27729.1 - 0.066 12.3 1.7 0.06 12.4 0.3 1.7 2 0 0 2 2 2 0 Filoviridae VP35 AhpC-TSA PF00578.21 KDO27730.1 - 5.4e-33 113.5 0.0 7.1e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO27730.1 - 3.2e-14 52.9 0.0 4.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KDO27730.1 - 2.1e-06 27.5 0.0 4.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LRR_6 PF13516.6 KDO27731.1 - 2.1e-14 52.2 5.8 0.0027 17.6 0.2 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KDO27731.1 - 1.2 9.6 10.9 69 4.1 0.1 5.2 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Nuc_sug_transp PF04142.15 KDO27732.1 - 5.4e-07 29.1 0.7 9.5e-07 28.3 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KDO27732.1 - 0.0013 18.0 7.4 0.0013 18.0 7.4 2.1 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport Na_Ca_ex PF01699.24 KDO27732.1 - 0.034 14.1 0.8 0.034 14.1 0.8 3.4 3 1 0 3 3 3 0 Sodium/calcium exchanger protein TraQ PF09679.10 KDO27732.1 - 2.6 8.1 4.6 1.3 8.9 0.5 2.6 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) EamA PF00892.20 KDO27732.1 - 5.1 7.3 27.9 0.059 13.5 5.5 3.7 3 2 1 4 4 4 0 EamA-like transporter family SET PF00856.28 KDO27733.1 - 1.2e-11 45.3 0.1 2.2e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 KDO27733.1 - 0.0012 18.9 12.6 0.0012 18.9 12.6 3.3 3 0 0 3 3 3 2 MYND finger Nuc_sug_transp PF04142.15 KDO27734.1 - 1.3e-06 27.8 11.0 3.1e-06 26.6 11.0 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KDO27734.1 - 0.0034 16.4 5.5 0.0034 16.4 5.5 2.4 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like MerE PF05052.12 KDO27734.1 - 0.013 15.4 1.8 9.7 6.2 0.0 3.6 3 0 0 3 3 3 0 MerE protein SHNi-TPR PF10516.9 KDO27735.1 - 1.7e-08 33.7 0.0 4.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 KDO27735.1 - 7.2e-05 22.6 1.9 0.52 10.5 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO27735.1 - 0.0024 17.6 0.2 3.9 7.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO27735.1 - 0.0039 17.3 0.5 0.31 11.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27735.1 - 0.004 17.4 0.6 4.5 7.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO27735.1 - 0.045 13.6 0.7 1.4 8.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LupA PF18242.1 KDO27735.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Synaptobrevin PF00957.21 KDO27737.1 - 2.6e-17 62.4 2.4 3.2e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 KDO27737.1 - 0.0001 22.3 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain DASH_Dad2 PF08654.10 KDO27737.1 - 0.1 13.0 0.5 1.9 9.0 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF4884 PF16225.5 KDO27737.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Med9 PF07544.13 KDO27737.1 - 1.3 9.2 4.5 4.2 7.5 0.6 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Taxilin PF09728.9 KDO27738.1 - 1.1e-58 198.9 41.6 1.9e-58 198.1 41.6 1.3 1 1 0 1 1 1 1 Myosin-like coiled-coil protein Hrs_helical PF12210.8 KDO27738.1 - 0.01 16.4 0.7 0.01 16.4 0.7 4.0 2 1 3 5 5 5 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TMF_TATA_bd PF12325.8 KDO27738.1 - 0.015 15.5 5.5 0.015 15.5 5.5 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 KDO27738.1 - 0.017 15.4 3.9 0.6 10.5 0.1 4.0 3 0 0 3 3 3 0 TSC-22/dip/bun family IFT57 PF10498.9 KDO27738.1 - 0.028 13.4 26.6 0.02 13.9 17.8 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 KDO27738.1 - 0.43 11.0 36.6 1.4 9.3 11.8 2.1 1 1 0 2 2 2 0 Fez1 DUF4201 PF13870.6 KDO27738.1 - 0.61 9.8 34.1 7.5 6.3 21.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Lebercilin PF15619.6 KDO27738.1 - 1 9.0 42.9 1.3 8.7 20.8 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 KDO27738.1 - 1.3 9.3 42.4 26 5.0 25.3 3.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 KDO27738.1 - 1.3 8.5 34.5 0.031 13.8 3.7 3.5 1 1 2 3 3 2 0 Leucine zipper UPF0242 PF06785.11 KDO27738.1 - 1.6 8.8 39.1 0.056 13.6 12.8 3.0 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KDO27738.1 - 2.6 7.8 42.8 0.024 14.5 11.6 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family NPV_P10 PF05531.12 KDO27738.1 - 2.7 8.5 16.6 3 8.4 1.1 4.3 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3708 PF12501.8 KDO27738.1 - 4.1 7.2 7.4 0.76 9.6 2.4 2.2 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Spc7 PF08317.11 KDO27738.1 - 5.1 5.9 39.1 0.53 9.1 12.1 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 KDO27738.1 - 5.1 7.3 28.5 0.61 10.2 1.2 5.3 3 1 4 7 7 7 0 bZIP transcription factor YabA PF06156.13 KDO27738.1 - 8.3 7.1 28.1 0.18 12.5 1.9 4.2 1 1 3 4 4 4 0 Initiation control protein YabA DUF1284 PF06935.11 KDO27738.1 - 9.5 6.7 10.8 0.54 10.7 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1284) TruD PF01142.18 KDO27739.1 - 3.4e-69 233.7 0.0 1.2e-63 215.4 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) UL21a PF17636.2 KDO27739.1 - 0.02 14.9 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Viral Unique Long protein 21a DUF4007 PF13182.6 KDO27739.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) zf_CopZ PF18423.1 KDO27740.1 - 0.039 13.9 0.5 0.11 12.5 0.5 1.7 1 0 0 1 1 1 0 Zinc binding domain Brix PF04427.18 KDO27741.1 - 2.9e-43 148.2 0.1 4.3e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain PT PF04886.12 KDO27741.1 - 0.16 11.5 1.8 0.27 10.8 1.8 1.3 1 0 0 1 1 1 0 PT repeat Hexapep PF00132.24 KDO27742.1 - 2.6e-17 61.8 16.5 5.5e-12 44.9 6.1 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KDO27742.1 - 7.5e-16 57.6 16.7 8.2e-11 41.5 5.6 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KDO27742.1 - 3.9e-10 39.8 0.1 7e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase TBCC PF07986.12 KDO27743.1 - 6.1e-13 48.6 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TPR_2 PF07719.17 KDO27744.1 - 2e-17 61.8 0.8 0.00011 22.0 0.0 4.3 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO27744.1 - 2.2e-16 58.9 1.4 0.0001 21.9 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO27744.1 - 4.6e-14 51.4 0.9 0.0065 16.6 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27744.1 - 5.4e-07 29.9 0.0 0.84 10.6 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO27744.1 - 6.7e-07 29.3 7.7 0.13 12.7 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO27744.1 - 1.6e-06 28.3 0.8 0.081 13.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO27744.1 - 3.7e-06 27.5 0.0 0.0045 17.6 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27744.1 - 4.8e-06 27.0 0.2 0.1 13.1 0.1 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27744.1 - 0.0002 21.6 2.8 0.35 11.2 0.0 3.3 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO27744.1 - 0.00024 20.9 3.2 0.15 12.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO27744.1 - 0.0015 18.6 0.2 0.32 11.2 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KDO27744.1 - 0.024 13.8 0.1 0.04 13.1 0.1 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO27744.1 - 0.04 13.3 0.0 0.066 12.6 0.0 1.5 1 1 0 1 1 1 0 MalT-like TPR region ANAPC3 PF12895.7 KDO27744.1 - 0.46 10.7 4.2 2.5 8.4 3.9 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mito_carr PF00153.27 KDO27746.1 - 4.7e-66 218.8 0.2 4.2e-21 74.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KDO27746.1 - 4.5e-13 49.4 0.0 1.6e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO27746.1 - 1e-08 34.9 0.2 0.0033 17.2 0.0 3.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO27746.1 - 6.9e-07 28.4 0.1 0.035 13.7 0.1 4.4 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KDO27746.1 - 2e-06 27.3 0.2 0.12 12.4 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 KDO27746.1 - 0.00023 21.4 0.1 0.0089 16.3 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain Serine_protease PF18405.1 KDO27746.1 - 0.14 11.3 0.3 9.9 5.2 0.1 2.9 2 1 0 2 2 2 0 Gammaproteobacterial serine protease JmjC PF02373.22 KDO27747.1 - 1.6e-36 125.2 0.1 2.9e-36 124.4 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KDO27747.1 - 2.8e-11 43.2 0.2 7e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KDO27747.1 - 2e-07 31.3 11.1 4.5e-07 30.1 11.1 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger Pns11_12 PF17464.2 KDO27747.1 - 1.9 8.2 3.3 3.2 7.4 3.3 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Hydrolase_4 PF12146.8 KDO27748.1 - 7.8e-57 192.3 0.3 9.9e-57 191.9 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO27748.1 - 2e-13 51.5 11.8 2.8e-13 51.0 11.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO27748.1 - 4.7e-11 42.8 0.7 2.9e-10 40.2 0.3 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO27748.1 - 5.8e-05 22.7 0.0 0.00054 19.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1749 PF08538.10 KDO27748.1 - 0.023 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.16 KDO27748.1 - 0.025 14.4 0.0 0.36 10.6 0.0 2.2 1 1 1 3 3 3 0 Phospholipase/Carboxylesterase PYRIN PF02758.16 KDO27750.1 - 0.0081 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain NfeD PF01957.18 KDO27751.1 - 0.091 13.1 0.0 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Y_phosphatase PF00102.27 KDO27752.1 - 8.1e-65 218.7 0.0 1.2e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KDO27752.1 - 5.7e-06 26.2 0.1 4.9e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO27752.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KDO27752.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate MBOAT_2 PF13813.6 KDO27752.1 - 0.067 13.5 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family MdcE PF06833.11 KDO27752.1 - 0.086 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) F-box-like PF12937.7 KDO27754.1 - 1.6e-09 37.5 1.4 3.3e-09 36.5 1.4 1.5 1 0 0 1 1 1 1 F-box-like DUF525 PF04379.14 KDO27754.1 - 3.4e-09 36.8 0.0 8.2e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 ApaG domain F-box PF00646.33 KDO27754.1 - 2.7e-05 23.9 0.7 6.3e-05 22.7 0.7 1.7 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KDO27754.1 - 0.0067 16.0 0.7 0.013 15.0 0.7 1.5 1 0 0 1 1 1 1 F-box IQ PF00612.27 KDO27755.1 - 0.00076 19.1 28.2 0.038 13.8 1.8 6.5 6 0 0 6 6 6 4 IQ calmodulin-binding motif WW PF00397.26 KDO27755.1 - 0.1 12.7 0.6 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 WW domain BT1 PF03092.16 KDO27756.1 - 4.2e-09 35.2 3.1 4.2e-09 35.2 3.1 3.0 3 1 0 3 3 3 1 BT1 family PUCC PF03209.15 KDO27756.1 - 0.001 18.1 1.0 0.001 18.1 1.0 2.3 2 0 0 2 2 2 1 PUCC protein Wzy_C_2 PF11846.8 KDO27756.1 - 4.1 7.3 6.0 1 9.3 0.3 2.7 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF2085 PF09858.9 KDO27756.1 - 6.8 7.2 15.5 1.5 9.3 2.4 4.2 5 0 0 5 5 5 0 Predicted membrane protein (DUF2085) GWT1 PF06423.12 KDO27758.1 - 4.4e-27 95.0 2.4 4.4e-27 95.0 2.4 3.0 3 1 0 3 3 3 1 GWT1 DUF4181 PF13789.6 KDO27758.1 - 2 8.7 9.8 0.75 10.1 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) RhodobacterPufX PF11511.8 KDO27759.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 Intrinsic membrane protein PufX PH PF00169.29 KDO27760.1 - 0.0059 17.1 0.1 0.036 14.6 0.0 2.2 2 1 0 2 2 2 1 PH domain DUF2458 PF10454.9 KDO27760.1 - 1 9.0 7.3 2.2 7.9 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) NHL PF01436.21 KDO27761.1 - 2.4e-22 77.8 12.5 6.8e-08 32.2 0.0 7.6 6 0 0 6 6 6 3 NHL repeat EGF_2 PF07974.13 KDO27761.1 - 6.6e-18 64.8 172.4 0.0034 17.7 9.2 13.0 13 0 0 13 13 13 10 EGF-like domain LCCL PF03815.19 KDO27761.1 - 8.2e-16 57.9 0.1 8.2e-16 57.9 0.1 2.6 3 0 0 3 3 3 1 LCCL domain hEGF PF12661.7 KDO27761.1 - 9e-08 32.5 142.4 0.009 16.6 5.5 13.0 11 0 0 11 11 11 7 Human growth factor-like EGF EGF PF00008.27 KDO27761.1 - 2.2e-07 31.1 138.3 0.0046 17.2 4.3 12.1 11 0 0 11 11 11 8 EGF-like domain SGL PF08450.12 KDO27761.1 - 2.7e-05 23.9 0.3 0.16 11.5 0.0 3.1 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region PEP-utilizers PF00391.23 KDO27761.1 - 0.13 11.9 0.9 26 4.6 0.1 2.9 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain TPR_2 PF07719.17 KDO27762.1 - 0.32 11.2 9.8 1.9 8.8 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO27762.1 - 3.5 7.6 8.1 18 5.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PDZ_6 PF17820.1 KDO27763.1 - 6e-12 45.2 2.9 0.042 13.7 0.1 5.8 6 0 0 6 6 6 5 PDZ domain PDZ PF00595.24 KDO27763.1 - 9.7e-12 45.1 0.0 0.29 11.5 0.0 5.8 5 0 0 5 5 5 5 PDZ domain PH PF00169.29 KDO27763.1 - 0.026 15.0 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 PH domain Peptidase_M16 PF00675.20 KDO27764.1 - 6.1e-54 182.1 0.3 9.7e-54 181.4 0.3 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO27764.1 - 1.4e-38 132.8 0.0 3.3e-37 128.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KDO27764.1 - 0.059 12.5 0.4 0.13 11.4 0.4 1.5 1 1 0 1 1 1 0 Peptidase M16C associated RbsD_FucU PF05025.13 KDO27764.1 - 0.096 13.1 0.2 0.91 9.9 0.1 2.3 2 0 0 2 2 2 0 RbsD / FucU transport protein family Synaptobrevin PF00957.21 KDO27765.1 - 8.7e-22 76.7 1.2 1.4e-21 76.0 1.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KDO27765.1 - 1.1e-17 63.9 0.1 1.9e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain HIP1_clath_bdg PF16515.5 KDO27765.1 - 0.067 13.8 1.2 0.12 13.0 1.2 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Proteasome PF00227.26 KDO27766.1 - 2e-58 197.0 0.1 2.5e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO27766.1 - 6.2e-14 51.4 0.1 1.2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3842 PF12953.7 KDO27766.1 - 0.14 12.6 0.2 0.14 12.6 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3842) FA_hydroxylase PF04116.13 KDO27767.1 - 4.9e-12 46.3 16.3 1.5e-11 44.8 5.7 2.9 2 1 1 3 3 3 2 Fatty acid hydroxylase superfamily SieB PF14163.6 KDO27767.1 - 0.075 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B HPS6 PF15702.5 KDO27767.1 - 0.11 10.5 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein DUF3742 PF12553.8 KDO27767.1 - 0.12 12.5 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) MgtE PF01769.16 KDO27767.1 - 1.6 9.1 5.8 0.4 11.1 0.2 2.5 3 0 0 3 3 3 0 Divalent cation transporter Ribosomal_S8e PF01201.22 KDO27768.1 - 7.6e-50 168.6 5.0 4.2e-49 166.2 5.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Thiolase_N PF00108.23 KDO27769.1 - 1e-54 185.6 0.3 3.6e-54 183.9 0.2 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KDO27769.1 - 8.3e-35 119.1 0.0 2.5e-34 117.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.11 KDO27769.1 - 0.034 12.8 0.0 0.077 11.7 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KDO27769.1 - 0.072 12.7 0.1 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Peptidase_M24 PF00557.24 KDO27770.1 - 7.6e-46 156.4 0.0 1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KDO27770.1 - 8.1e-38 128.9 0.0 1.3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Piwi PF02171.17 KDO27771.1 - 6.3e-99 331.0 0.0 1.5e-98 329.8 0.0 1.7 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 KDO27771.1 - 1e-19 71.5 0.0 2.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KDO27771.1 - 2.8e-19 68.5 0.0 7.6e-19 67.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KDO27771.1 - 1.2e-16 60.8 0.0 1.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KDO27771.1 - 2.1e-07 31.1 0.0 5.8e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KDO27771.1 - 5.7e-07 29.8 0.0 1.9e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain PrgI PF12666.7 KDO27772.1 - 2.5 8.9 6.1 1.4 9.6 0.8 2.1 2 0 0 2 2 2 0 PrgI family protein DUF1330 PF07045.11 KDO27773.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) SNARE_assoc PF09335.11 KDO27775.1 - 2.7e-14 53.7 3.6 2.7e-14 53.7 3.6 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Beach PF02138.18 KDO27776.1 - 1.5e-113 378.8 0.0 2.5e-113 378.1 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KDO27776.1 - 7.4e-16 58.1 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KDO27776.1 - 4.2e-08 33.7 7.5 0.44 11.5 0.6 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 KDO27776.1 - 1.3e-06 28.2 6.1 3.2e-06 26.9 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Laminin_G_3 PF13385.6 KDO27776.1 - 0.0021 18.3 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily zf-C3HC4 PF00097.25 KDO27776.1 - 0.042 13.7 9.5 0.01 15.7 5.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4704 PF15787.5 KDO27776.1 - 0.042 13.1 8.8 0.012 14.9 5.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) zf-RING_5 PF14634.6 KDO27776.1 - 0.16 12.0 6.9 0.42 10.6 6.5 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KDO27776.1 - 0.27 11.1 11.9 0.038 13.8 6.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO27776.1 - 0.36 11.2 10.3 0.046 14.1 5.5 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_10 PF16685.5 KDO27776.1 - 0.43 10.7 4.9 1.1 9.4 4.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KDO27776.1 - 0.44 10.6 10.8 0.038 14.0 4.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO27776.1 - 1.7 8.9 11.2 0.41 10.8 7.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KDO27776.1 - 5.8 6.9 7.7 16 5.4 7.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PDEase_I PF00233.19 KDO27777.1 - 3.1e-47 161.3 0.1 4.3e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-MYND PF01753.18 KDO27778.1 - 1e-06 28.7 11.8 1.7e-06 28.0 11.8 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KDO27778.1 - 0.031 14.4 3.9 0.072 13.2 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PALP PF00291.25 KDO27779.1 - 1.7e-59 201.6 6.0 8e-59 199.4 6.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KDO27779.1 - 5e-35 119.1 0.0 1.1e-20 73.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Armet PF10208.9 KDO27780.1 - 9e-23 80.8 6.4 2e-22 79.7 6.4 1.5 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 KDO27780.1 - 3e-06 26.8 0.2 6.7e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 SAP domain CP12 PF02672.15 KDO27780.1 - 0.016 15.9 5.4 3.6 8.4 0.1 3.2 2 1 1 3 3 3 0 CP12 domain HeH PF12949.7 KDO27780.1 - 0.032 13.9 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain C1_2 PF03107.16 KDO27780.1 - 0.049 13.9 0.1 18 5.7 0.0 2.4 2 0 0 2 2 2 0 C1 domain ArfGap PF01412.18 KDO27781.1 - 7.7e-31 106.6 0.1 7.7e-31 106.6 0.1 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BTB PF00651.31 KDO27782.1 - 1.3e-22 80.1 0.3 4.7e-22 78.3 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain FYVE PF01363.21 KDO27782.1 - 8.5e-16 57.9 10.4 2.1e-15 56.6 10.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger NAD_binding_10 PF13460.6 KDO27782.1 - 1.1e-12 48.3 0.0 2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KDO27782.1 - 1.3e-08 34.7 0.2 1.5e-07 31.1 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KDO27782.1 - 1.2e-06 27.7 0.0 2.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Arm PF00514.23 KDO27782.1 - 0.0016 18.4 0.7 0.017 15.2 0.0 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Sulfotransfer_4 PF17784.1 KDO27782.1 - 0.0049 16.7 0.4 0.45 10.3 0.0 2.7 3 0 0 3 3 3 1 Sulfotransferase domain NmrA PF05368.13 KDO27782.1 - 0.0068 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KDO27782.1 - 0.0091 15.2 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KDO27782.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FYVE_2 PF02318.16 KDO27782.1 - 0.057 13.6 7.8 0.16 12.2 7.8 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3342 PF11822.8 KDO27782.1 - 0.088 13.0 0.1 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) FYVE PF01363.21 KDO27783.1 - 3.4e-14 52.7 13.0 7.7e-14 51.6 13.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger NAD_binding_10 PF13460.6 KDO27783.1 - 1.7e-11 44.3 0.0 3.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding BTB PF00651.31 KDO27783.1 - 1.2e-10 41.6 0.0 3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Epimerase PF01370.21 KDO27783.1 - 6.1e-10 39.0 0.1 1.2e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KDO27783.1 - 1.9e-05 23.8 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KDO27783.1 - 0.00037 20.0 0.0 0.003 17.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase BACK PF07707.15 KDO27783.1 - 0.13 12.3 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch FYVE_2 PF02318.16 KDO27783.1 - 1.4 9.1 8.3 4.1 7.6 8.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_16 PF00722.21 KDO27784.1 - 2.4e-30 105.3 0.1 3.1e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KDO27784.1 - 3.1e-13 49.0 0.6 2.3e-10 39.5 0.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 KDO27785.1 - 1.9e-37 128.4 0.0 2.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KDO27785.1 - 6.9e-16 57.7 0.1 8.5e-09 34.3 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 KDO27787.1 - 9.2e-33 113.2 0.0 1.2e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KDO27787.1 - 2.6e-21 75.6 0.0 8.3e-10 37.7 0.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Exo_endo_phos PF03372.23 KDO27788.1 - 3.5e-07 30.0 0.3 6.2e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dicty_CAR PF05462.11 KDO27788.1 - 4.2e-07 29.4 8.6 6.5e-07 28.8 8.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KDO27788.1 - 0.013 15.6 0.2 0.29 11.2 0.1 2.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term PIP5K PF01504.18 KDO27789.1 - 1.1e-42 146.2 0.0 5.1e-41 140.7 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 KDO27789.1 - 1.4e-17 63.6 10.0 1.4e-17 63.6 10.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 KDO27789.1 - 6.2e-17 61.4 0.1 1e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE_2 PF02318.16 KDO27789.1 - 4.9 7.4 8.9 19 5.5 8.0 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger COG2 PF06148.11 KDO27791.1 - 5.6e-25 88.0 0.3 1.5e-24 86.6 0.3 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 KDO27791.1 - 3.7e-24 85.5 0.0 1e-23 84.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 KDO27791.1 - 0.11 12.5 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 Macoilin PF09726.9 KDO27793.1 - 0.0055 15.3 12.2 0.0067 15.0 12.2 1.0 1 0 0 1 1 1 1 Macoilin family mRNA_cap_enzyme PF01331.19 KDO27794.1 - 2e-34 119.1 0.0 3.5e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 KDO27794.1 - 7.4e-05 22.5 0.0 0.00031 20.5 0.0 1.8 1 1 1 2 2 2 1 ATP dependent DNA ligase domain DSPc PF00782.20 KDO27794.1 - 0.0053 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain tRNA_synthFbeta PF17759.1 KDO27796.1 - 1.8e-47 161.6 0.0 5.4e-47 160.0 0.0 1.7 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KDO27796.1 - 9.4e-35 118.7 0.2 5.1e-33 113.1 0.0 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KDO27796.1 - 4e-26 91.7 0.0 6.8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KDO27796.1 - 3.1e-13 49.8 0.1 6.6e-11 42.4 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetase B5 domain AAA PF00004.29 KDO27797.1 - 3.2e-40 137.6 0.0 6.3e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KDO27797.1 - 1e-09 38.2 0.1 2.1e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KDO27797.1 - 3.9e-09 36.2 0.1 7.5e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KDO27797.1 - 3.4e-06 27.4 0.2 0.0017 18.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KDO27797.1 - 8.5e-06 26.0 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KDO27797.1 - 2.2e-05 23.8 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KDO27797.1 - 5.7e-05 23.1 0.1 0.00033 20.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO27797.1 - 0.00013 22.4 0.2 0.0019 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO27797.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KDO27797.1 - 0.0053 16.1 0.1 0.11 11.9 0.1 2.3 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.22 KDO27797.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KDO27797.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KDO27797.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 KDO27797.1 - 0.027 14.3 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KDO27797.1 - 0.047 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 KDO27797.1 - 0.047 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO27797.1 - 0.047 13.4 0.2 0.12 12.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO27797.1 - 0.056 13.7 0.1 0.13 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KDO27797.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KDO27797.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KDO27797.1 - 0.091 12.7 0.2 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KDO27797.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KDO27797.1 - 0.13 11.7 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KDO27797.1 - 0.14 11.6 0.1 0.32 10.5 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KDO27797.1 - 0.22 11.1 0.6 1.3 8.6 0.1 2.1 1 1 1 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KDO27797.1 - 0.54 9.9 3.3 0.36 10.5 0.1 2.3 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain Lipase_GDSL_2 PF13472.6 KDO27798.1 - 1.7e-26 93.7 0.1 2.1e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO27798.1 - 2.8e-13 50.3 0.0 5.7e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2353 PF09789.9 KDO27799.1 - 0.0045 16.4 2.9 0.0067 15.8 2.9 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.21 KDO27799.1 - 0.015 15.4 10.2 0.015 15.4 10.2 3.1 3 0 0 3 3 3 0 bZIP transcription factor Prominin PF05478.11 KDO27799.1 - 0.17 9.8 1.5 0.26 9.2 1.5 1.2 1 0 0 1 1 1 0 Prominin IATP PF04568.12 KDO27799.1 - 0.68 10.4 14.5 0.033 14.6 4.0 2.7 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP bZIP_Maf PF03131.17 KDO27799.1 - 2 9.0 10.8 2.3 8.8 9.6 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor HR1 PF02185.16 KDO27799.1 - 8.5 6.6 11.9 4.9 7.4 5.8 2.3 2 0 0 2 2 2 0 Hr1 repeat Carn_acyltransf PF00755.20 KDO27800.1 - 5.1e-188 626.4 0.0 5.8e-188 626.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Kinetochor_Ybp2 PF08568.10 KDO27802.1 - 1.5e-07 30.3 0.1 2.8e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Cwf_Cwc_15 PF04889.12 KDO27802.1 - 0.025 14.3 0.7 0.044 13.5 0.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sulfotransfer_3 PF13469.6 KDO27802.1 - 0.026 14.9 0.5 0.075 13.4 0.1 1.9 2 0 0 2 2 2 0 Sulfotransferase family IQ PF00612.27 KDO27803.1 - 1.8e-07 30.3 29.1 0.0038 16.9 0.9 6.6 5 1 1 6 6 6 4 IQ calmodulin-binding motif RDM PF11002.8 KDO27803.1 - 0.15 12.1 0.5 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RFPL defining motif (RDM) Mg_trans_NIPA PF05653.14 KDO27804.1 - 3.8e-77 259.3 31.8 4.2e-43 147.6 13.5 2.4 2 1 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KDO27804.1 - 2.2e-09 37.6 13.3 2.3e-06 27.8 5.2 5.1 5 1 1 6 6 6 2 EamA-like transporter family DUF3392 PF11872.8 KDO27804.1 - 0.032 14.5 1.1 0.032 14.5 1.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3392) Helicase_C PF00271.31 KDO27804.1 - 0.047 14.0 0.0 92 3.4 0.0 3.4 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Jagunal PF07086.12 KDO27804.1 - 0.052 13.6 10.0 0.11 12.6 3.8 3.8 2 1 1 3 3 3 0 Jagunal, ER re-organisation during oogenesis DMT_6 PF04342.12 KDO27804.1 - 0.16 12.1 9.3 0.089 13.0 0.6 3.5 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) MadM PF03818.13 KDO27804.1 - 3.1 7.7 8.4 1.6 8.7 0.6 3.7 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit CRAL_TRIO PF00650.20 KDO27806.1 - 9e-27 93.7 0.0 1.4e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KDO27806.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KDO27807.1 - 1.1e-26 93.5 0.1 5.2e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain DEP PF00610.21 KDO27807.1 - 8.2e-13 48.2 0.1 2.4e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KDO27807.1 - 1.5e-08 35.1 0.1 3.6e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 KDO27807.1 - 0.33 10.7 1.5 0.37 10.6 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Smr PF01713.21 KDO27808.1 - 0.00021 21.6 0.1 0.0004 20.7 0.1 1.5 1 0 0 1 1 1 1 Smr domain Rtt106 PF08512.12 KDO27809.1 - 0.053 14.0 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone Rttp106-like SpoIIE PF07228.12 KDO27810.1 - 6.2e-10 39.3 0.1 8.5e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KDO27810.1 - 5.5e-05 22.9 0.1 9.6e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KDO27810.1 - 0.00016 21.4 0.0 0.048 13.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C DUF4716 PF15837.5 KDO27810.1 - 0.11 12.6 0.8 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) Elicitin PF00964.17 KDO27811.1 - 2.8e-14 53.0 2.0 3.9e-14 52.5 2.0 1.3 1 0 0 1 1 1 1 Elicitin MFS_1 PF07690.16 KDO27812.1 - 1.5e-33 116.2 27.5 1.5e-33 116.2 27.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO27812.1 - 2.1e-16 59.8 20.5 3.4e-16 59.2 20.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KDO27812.1 - 2.8e-05 22.6 3.8 2.8e-05 22.6 3.8 3.3 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family HGTP_anticodon PF03129.20 KDO27813.1 - 2.4e-19 69.3 0.0 5.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KDO27813.1 - 1.9e-12 47.5 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn-ribbon_8 PF09723.10 KDO27813.1 - 0.0033 17.5 0.6 2.6 8.2 0.2 2.6 2 0 0 2 2 2 2 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KDO27813.1 - 0.12 13.2 0.3 0.27 12.0 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KDO27813.1 - 0.39 10.2 1.6 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1_like PF12832.7 KDO27814.1 - 1.9e-64 217.9 27.2 3e-64 217.3 27.2 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO27814.1 - 2.8e-27 95.6 57.4 7.4e-20 71.2 33.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO27814.1 - 7.1e-15 54.9 20.0 9.3e-15 54.5 20.0 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO27814.1 - 1.6e-12 47.0 17.2 2.1e-12 46.5 17.2 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 KDO27814.1 - 5.3e-07 28.6 27.2 0.00038 19.2 4.9 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Wzz PF02706.15 KDO27814.1 - 0.23 11.8 1.2 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Chain length determinant protein MFS_3 PF05977.13 KDO27814.1 - 0.43 8.9 13.6 1 7.7 13.6 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector Nucleoside_tran PF01733.18 KDO27815.1 - 1.5e-17 64.0 8.8 4.4e-16 59.1 8.8 2.1 1 1 0 1 1 1 1 Nucleoside transporter MFS_1_like PF12832.7 KDO27816.1 - 3e-55 187.6 18.3 4.7e-55 187.0 18.3 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO27816.1 - 3.9e-13 49.1 65.1 1.7e-12 47.0 35.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO27816.1 - 1.4e-11 44.0 17.0 1.9e-11 43.6 17.0 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO27816.1 - 5.7e-06 25.4 12.5 5.5e-05 22.1 12.5 2.4 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.7 KDO27817.1 - 2.6e-62 210.9 21.1 3.7e-62 210.4 21.1 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO27817.1 - 6.6e-19 68.0 41.1 3.1e-12 46.1 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KDO27817.1 - 3.9e-13 49.2 16.8 6.7e-13 48.4 16.8 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KDO27817.1 - 1e-09 37.7 13.8 1.4e-09 37.3 13.8 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 KDO27817.1 - 2.3e-06 26.4 24.5 0.0021 16.7 10.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 KDO27817.1 - 0.0016 16.9 18.6 0.0036 15.8 18.6 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector SDF PF00375.18 KDO27818.1 - 3.8e-62 210.6 41.0 5.9e-62 209.9 41.0 1.2 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5409 PF17421.2 KDO27818.1 - 0.067 13.9 0.3 0.27 12.0 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5409) SDF PF00375.18 KDO27820.1 - 1.3e-70 238.4 35.1 5e-70 236.5 35.1 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5409 PF17421.2 KDO27820.1 - 1.1 10.0 3.6 0.76 10.5 0.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5409) PhoLip_ATPase_C PF16212.5 KDO27821.1 - 5.4e-47 160.6 9.1 6.3e-47 160.4 9.1 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 KDO27821.1 - 0.0039 17.0 0.1 0.0058 16.4 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KDO27822.1 - 4.6e-24 83.9 0.3 1e-23 82.8 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KDO27822.1 - 6.7e-11 42.0 0.4 6.7e-11 42.0 0.4 1.6 2 0 0 2 2 2 1 E1-E2 ATPase tRNA-synt_1 PF00133.22 KDO27823.1 - 9e-133 443.6 0.0 2.2e-88 297.0 0.0 3.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KDO27823.1 - 4.2e-37 127.4 0.0 6.7e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KDO27823.1 - 9.8e-08 31.7 0.0 3.8e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KDO27823.1 - 5.5e-05 22.1 0.0 0.11 11.2 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KDO27824.1 - 4.1e-07 30.2 2.2 7.4e-07 29.4 1.5 1.7 1 1 1 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Inhibitor_Mig-6 PF11555.8 KDO27824.1 - 0.093 12.8 0.3 0.14 12.2 0.3 1.5 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 TPR_1 PF00515.28 KDO27826.1 - 2e-51 169.8 22.9 0.00061 19.5 0.0 18.5 18 1 0 18 18 18 10 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27826.1 - 2.4e-39 130.3 36.9 0.001 19.0 0.4 16.9 17 1 0 17 17 17 9 Tetratricopeptide repeat TPR_11 PF13414.6 KDO27826.1 - 9e-29 98.9 15.6 5.4e-05 22.8 0.0 13.9 9 5 5 14 14 14 7 TPR repeat TPR_16 PF13432.6 KDO27826.1 - 4.1e-26 91.4 37.4 0.00015 22.3 2.7 11.5 7 3 3 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KDO27826.1 - 1.9e-24 83.8 18.9 0.01 16.0 0.0 13.2 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_9 PF13371.6 KDO27826.1 - 1.7e-21 76.2 32.6 0.0028 17.8 0.2 10.6 5 2 7 12 12 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 KDO27826.1 - 7e-16 58.5 5.7 0.01 16.3 0.2 7.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO27826.1 - 4.7e-14 51.7 10.2 0.022 15.1 0.0 9.5 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27826.1 - 1.2e-11 44.7 36.0 0.003 17.8 0.3 10.4 5 3 6 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27826.1 - 1.3e-06 28.7 33.8 4.4 8.4 0.1 14.3 6 4 11 17 17 15 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO27826.1 - 0.00011 22.6 17.2 29 5.6 0.0 11.4 14 0 0 14 14 12 0 Tetratricopeptide repeat TPR_15 PF13429.6 KDO27826.1 - 0.00032 20.0 5.3 0.25 10.5 0.1 5.5 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO27826.1 - 0.0031 17.4 18.7 22 5.3 0.0 11.0 14 0 0 14 14 12 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO27826.1 - 0.037 14.3 0.1 0.037 14.3 0.1 7.2 5 2 3 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KDO27826.1 - 0.059 13.7 7.5 9.3 6.7 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Vta1_C PF18097.1 KDO27826.1 - 0.083 12.6 0.0 1.6 8.5 0.0 3.2 2 0 0 2 2 2 0 Vta1 C-terminal domain NARP1 PF12569.8 KDO27826.1 - 0.2 10.6 8.5 3.7 6.3 0.1 3.8 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Paf67 PF10255.9 KDO27826.1 - 0.26 10.2 3.7 1.7 7.6 0.2 2.9 4 0 0 4 4 4 0 RNA polymerase I-associated factor PAF67 BTAD PF03704.17 KDO27826.1 - 7.4 7.0 11.6 4.4 7.7 0.0 4.9 4 2 2 6 6 5 0 Bacterial transcriptional activator domain HSP90 PF00183.18 KDO27827.1 - 6.2e-236 784.3 22.3 7.8e-236 783.9 22.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KDO27827.1 - 6.5e-13 49.2 0.1 1.2e-12 48.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KDO27827.1 - 5e-09 36.1 0.2 1.1e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 KDO27827.1 - 1.2 9.3 15.5 0.018 15.1 6.5 2.2 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ank_4 PF13637.6 KDO27828.1 - 1.2e-13 51.3 10.7 9.7e-07 29.2 0.7 4.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO27828.1 - 5.1e-09 36.6 1.8 0.0049 17.4 0.3 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO27828.1 - 8.9e-05 22.7 3.5 14 6.2 0.0 5.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27828.1 - 0.00012 22.2 4.8 0.55 11.0 0.0 5.6 5 1 1 6 6 6 1 Ankyrin repeat MCM PF00493.23 KDO27829.1 - 1.5e-85 285.9 0.0 2.1e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KDO27829.1 - 5.2e-28 97.3 2.0 1e-27 96.4 2.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KDO27829.1 - 8.1e-23 80.6 0.2 1.4e-22 79.9 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KDO27829.1 - 4.5e-09 36.0 0.5 4.6e-06 26.2 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO27829.1 - 5.3e-09 36.2 0.0 1.9e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KDO27829.1 - 0.00014 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KDO27829.1 - 0.00029 20.6 0.0 0.0049 16.6 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 KDO27829.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KDO27829.1 - 0.021 15.0 0.1 7 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO27829.1 - 0.053 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 4HBT PF03061.22 KDO27830.1 - 2.2e-19 69.6 0.3 1.8e-10 41.0 0.1 2.5 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 KDO27830.1 - 0.22 11.1 1.3 0.63 9.6 0.1 2.1 2 0 0 2 2 2 0 MaoC like domain 4HBT PF03061.22 KDO27831.1 - 3.8e-21 75.2 0.3 1e-13 51.4 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 KDO27831.1 - 0.0001 21.8 0.3 0.15 11.6 0.5 2.4 2 0 0 2 2 2 2 MaoC like domain Adeno_E3_15_3 PF03307.14 KDO27831.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Dev_Cell_Death PF10539.9 KDO27832.1 - 1.1e-19 70.6 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Development and cell death domain PLAC8 PF04749.17 KDO27833.1 - 1.1e-11 45.6 4.1 2.3e-11 44.6 4.1 1.5 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KDO27834.1 - 4.2e-20 72.6 11.2 7.4e-20 71.8 11.2 1.4 1 1 0 1 1 1 1 PLAC8 family DUF347 PF03988.12 KDO27834.1 - 0.12 12.6 1.3 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) HECT PF00632.25 KDO27835.1 - 5.5e-92 308.5 0.0 7.9e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) G6PD_N PF00479.22 KDO27836.1 - 6e-27 95.4 0.0 3e-23 83.4 0.0 2.4 3 0 0 3 3 3 2 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 KDO27836.1 - 1.8e-15 56.9 0.0 3e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain GFO_IDH_MocA PF01408.22 KDO27836.1 - 0.031 15.1 0.2 0.078 13.8 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TMP-TENI PF02581.17 KDO27840.1 - 1.9e-48 164.2 2.4 2.2e-48 164.0 2.4 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 KDO27840.1 - 0.0089 15.4 1.9 0.0089 15.4 1.9 2.3 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KDO27840.1 - 0.017 14.3 1.3 0.017 14.3 1.3 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF561) PH PF00169.29 KDO27841.1 - 0.0002 21.8 0.0 0.00031 21.2 0.0 1.2 1 0 0 1 1 1 1 PH domain Endosulfine PF04667.17 KDO27842.1 - 1.9e-32 111.2 4.0 6.7e-11 42.2 0.7 3.2 2 1 1 3 3 3 3 cAMP-regulated phosphoprotein/endosulfine conserved region T6SS-SciN PF12790.7 KDO27842.1 - 0.067 12.9 0.9 28 4.5 0.1 3.0 3 0 0 3 3 3 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Nucleic_acid_bd PF13820.6 KDO27842.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative nucleic acid-binding region AAA PF00004.29 KDO27843.1 - 8.8e-39 133.0 0.1 2.1e-38 131.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO27843.1 - 1.5e-10 40.7 0.0 6.3e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KDO27843.1 - 4.5e-09 36.2 0.0 2.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KDO27843.1 - 1.5e-06 28.1 0.0 3.8e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO27843.1 - 2e-06 27.8 0.1 5.4e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO27843.1 - 0.001 19.3 3.2 0.018 15.3 0.8 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KDO27843.1 - 0.0017 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KDO27843.1 - 0.0027 17.0 0.1 0.0065 15.7 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KDO27843.1 - 0.0084 16.5 0.7 0.069 13.5 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KDO27843.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KDO27843.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KDO27843.1 - 0.12 11.7 0.3 0.24 10.7 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KDO27843.1 - 0.25 10.9 0.7 6.2 6.3 0.2 2.4 1 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KDO27843.1 - 0.43 9.9 2.1 4.4 6.6 0.3 2.2 1 1 1 2 2 2 0 KaiC Hist_deacetyl PF00850.19 KDO27844.1 - 3e-73 247.0 0.0 4.1e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain UPRTase PF14681.6 KDO27845.1 - 7.8e-71 237.8 0.0 9.6e-71 237.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KDO27845.1 - 0.00041 19.9 0.4 0.0011 18.6 0.4 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_2 PF00890.24 KDO27846.1 - 5.4e-75 253.0 4.4 6.5e-75 252.8 4.4 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KDO27846.1 - 9.7e-14 51.7 2.3 3.1e-09 36.9 0.2 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO27846.1 - 8.4e-09 35.1 1.7 6.7e-08 32.1 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO27846.1 - 2.5e-08 34.0 0.1 8.3e-07 29.1 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KDO27846.1 - 1.9e-07 30.8 2.2 3.8e-07 29.8 2.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KDO27846.1 - 3.5e-07 29.7 0.6 3.9e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KDO27846.1 - 7.7e-06 24.9 7.8 0.011 14.5 0.2 3.2 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_3 PF13738.6 KDO27846.1 - 0.00082 18.7 0.2 0.68 9.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO27846.1 - 0.00096 18.3 0.7 0.0026 16.9 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KDO27846.1 - 0.001 18.2 6.8 0.0013 17.9 2.6 2.6 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KDO27846.1 - 0.005 17.4 1.3 0.74 10.4 0.7 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KDO27846.1 - 0.0085 14.7 0.2 0.032 12.8 0.1 1.8 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KDO27846.1 - 0.015 15.3 1.3 0.15 12.1 1.3 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KDO27846.1 - 0.031 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KDO27846.1 - 0.085 12.0 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SRAP PF02586.14 KDO27847.1 - 4.1e-44 150.7 0.0 5e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Hydrolase_4 PF12146.8 KDO27848.1 - 1.4e-13 50.7 0.1 1.3e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO27848.1 - 3.1e-11 43.4 0.1 1.4e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO27848.1 - 2.9e-09 37.9 1.9 1.3e-08 35.7 1.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KDO27848.1 - 6.8e-08 32.2 0.0 1.4e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KDO27848.1 - 2.7e-07 29.6 0.1 0.0044 15.7 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 KDO27848.1 - 8e-05 22.3 0.0 0.00052 19.6 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KDO27848.1 - 0.0004 20.3 0.0 0.00087 19.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KDO27848.1 - 0.00051 19.8 0.0 0.00078 19.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KDO27848.1 - 0.0015 18.4 0.0 0.02 14.7 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KDO27848.1 - 0.0052 16.4 0.0 0.018 14.7 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KDO27848.1 - 0.012 15.5 0.0 0.079 12.9 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.12 KDO27848.1 - 0.022 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KDO27848.1 - 0.06 13.0 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein DUF818 PF05677.12 KDO27848.1 - 0.082 11.8 0.0 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Esterase_phd PF10503.9 KDO27848.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.25 KDO27848.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Steroid_dh PF02544.16 KDO27849.1 - 7.5e-31 107.1 1.7 1.1e-30 106.6 1.7 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KDO27849.1 - 0.0046 16.5 0.4 0.0081 15.7 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KDO27849.1 - 0.012 15.9 3.4 0.16 12.3 0.5 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.23 KDO27849.1 - 0.025 14.3 0.1 0.067 13.0 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin family zf-C3HC4_2 PF13923.6 KDO27850.1 - 3.7e-09 36.3 8.7 6.4e-09 35.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO27850.1 - 6.9e-08 32.2 7.9 1.2e-07 31.5 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO27850.1 - 7.4e-06 25.7 7.5 1.4e-05 24.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KDO27850.1 - 2.6e-05 24.0 4.7 4.4e-05 23.3 4.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KDO27850.1 - 3.3e-05 24.1 9.5 5.5e-05 23.4 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KDO27850.1 - 3.6e-05 23.6 9.3 7e-05 22.7 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO27850.1 - 0.0033 17.4 7.1 0.0034 17.4 3.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO27850.1 - 0.0039 17.0 8.0 0.0081 16.0 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO27850.1 - 0.0062 16.7 5.8 0.015 15.4 5.8 1.8 1 1 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KDO27850.1 - 0.01 16.0 6.6 0.018 15.2 6.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KDO27850.1 - 0.035 14.4 8.7 0.1 12.9 8.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO27850.1 - 0.035 14.1 3.9 0.053 13.6 3.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mob_synth_C PF06463.13 KDO27850.1 - 0.037 14.0 0.7 0.059 13.3 0.7 1.4 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Baculo_IE-1 PF05290.11 KDO27850.1 - 0.046 13.7 0.7 0.067 13.1 0.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Glutaredoxin PF00462.24 KDO27850.1 - 0.082 13.1 0.1 0.37 11.0 0.1 2.0 2 1 0 2 2 2 0 Glutaredoxin GAGA PF09237.11 KDO27850.1 - 0.28 11.0 6.9 0.58 10.0 2.3 2.4 1 1 1 2 2 2 0 GAGA factor zf-Nse PF11789.8 KDO27850.1 - 0.35 10.7 3.4 0.7 9.8 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Metallothio_Pro PF02069.16 KDO27850.1 - 0.7 10.2 5.3 1.7 9.0 0.1 2.3 1 1 1 2 2 2 0 Prokaryotic metallothionein zf-C3HC4_5 PF17121.5 KDO27850.1 - 0.93 9.4 6.1 6.7 6.7 6.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.20 KDO27851.1 - 5.5e-19 68.1 12.4 5.5e-19 68.1 12.4 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KDO27851.1 - 0.13 12.1 0.1 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS RRM_1 PF00076.22 KDO27852.1 - 1.4e-17 63.3 0.2 9.4e-17 60.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRP-L20 PF12824.7 KDO27852.1 - 0.02 15.1 1.9 0.02 15.1 1.9 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein subunit L20 RRM_7 PF16367.5 KDO27852.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO27852.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NYD-SP12_N PF15015.6 KDO27852.1 - 0.51 8.6 8.1 0.7 8.2 8.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Sec62 PF03839.16 KDO27852.1 - 0.57 9.6 8.6 0.88 9.0 8.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 WD40 PF00400.32 KDO27853.1 - 6.7e-16 58.4 0.0 0.0001 23.0 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27853.1 - 2e-05 24.8 0.0 1.3 9.4 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-UBR PF02207.20 KDO27854.1 - 3.3e-17 62.4 13.4 3.3e-17 62.4 13.4 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Acetyltransf_1 PF00583.25 KDO27855.1 - 3.2e-16 59.6 0.2 4.4e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO27855.1 - 1.1e-09 38.5 0.1 1.7e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO27855.1 - 1.7e-09 37.7 0.3 2e-09 37.4 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO27855.1 - 3.3e-07 30.2 0.1 6.5e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KDO27855.1 - 0.00064 19.8 0.3 0.0013 18.8 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO27855.1 - 0.0019 18.9 0.1 0.0026 18.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KDO27855.1 - 0.0044 17.0 0.1 0.0077 16.2 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase EGF_2 PF07974.13 KDO27856.1 - 5.6e-13 49.0 51.9 8.1e-05 22.9 3.4 6.4 6 0 0 6 6 6 4 EGF-like domain EGF PF00008.27 KDO27856.1 - 0.0046 17.2 40.6 0.9 9.9 7.1 5.1 5 0 0 5 5 5 4 EGF-like domain Laminin_EGF PF00053.24 KDO27856.1 - 0.39 10.9 39.0 0.22 11.7 8.3 4.1 4 1 0 4 4 4 0 Laminin EGF domain Tim17 PF02466.19 KDO27857.1 - 1e-09 38.7 5.8 4.6e-09 36.7 5.5 1.8 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 KDO27857.1 - 1.3 9.1 10.2 1.7 8.8 0.4 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Acetyltransf_1 PF00583.25 KDO27858.1 - 3.4e-07 30.5 0.1 4.9e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO27858.1 - 6.3e-06 26.2 0.1 8.8e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO27858.1 - 0.00058 20.2 0.1 0.0012 19.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO27858.1 - 0.0054 16.7 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein UPF0029 PF01205.19 KDO27859.1 - 4.7e-16 59.0 0.1 7.8e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 MT PF12777.7 KDO27859.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor EF-hand_8 PF13833.6 KDO27860.1 - 8.5e-20 70.4 2.5 9.5e-12 44.6 0.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KDO27860.1 - 8.8e-20 70.9 0.4 6.6e-13 48.9 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO27860.1 - 8.6e-18 62.5 7.2 2.6e-07 29.7 1.5 3.6 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO27860.1 - 5e-12 44.7 1.8 0.00015 21.4 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 KDO27860.1 - 4.2e-11 43.0 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO27860.1 - 4.2e-05 22.9 5.3 0.031 13.8 1.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 KDO27860.1 - 0.00089 19.2 0.2 0.0092 15.9 0.2 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF496 PF04363.12 KDO27860.1 - 0.093 12.8 0.4 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF496) LMBR1 PF04791.16 KDO27861.1 - 4.7e-43 147.9 37.4 3.7e-40 138.3 37.4 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein RIIa PF02197.17 KDO27862.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit EF-hand_6 PF13405.6 KDO27863.1 - 9.4e-15 53.2 7.7 0.00066 19.4 0.3 7.0 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 KDO27863.1 - 5.2e-12 46.0 0.1 0.00089 19.7 0.1 6.1 6 1 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO27863.1 - 6.9e-08 31.5 1.3 0.14 11.8 0.2 5.8 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.6 KDO27863.1 - 0.0096 15.4 0.2 0.051 13.1 0.2 2.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KDO27863.1 - 0.022 14.6 2.7 54 3.7 0.0 5.0 5 0 0 5 5 5 0 EF-hand domain pair EF-hand_2 PF09068.11 KDO27863.1 - 0.17 12.1 0.0 0.67 10.1 0.0 2.1 1 0 0 1 1 1 0 EF hand EamA PF00892.20 KDO27864.1 - 1.6e-06 28.3 7.0 1.8e-06 28.2 7.0 1.3 1 1 0 1 1 1 1 EamA-like transporter family UAA PF08449.11 KDO27864.1 - 0.00053 19.3 1.9 0.0006 19.1 1.9 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 KDO27864.1 - 0.0009 19.3 0.9 0.0011 18.9 0.9 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF3493 PF11998.8 KDO27864.1 - 0.044 13.9 3.0 0.15 12.2 1.8 2.0 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 RRM_1 PF00076.22 KDO27865.1 - 0.029 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KDO27866.1 - 4.1e-10 39.3 0.0 1.2e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HpcH_HpaI PF03328.14 KDO27868.1 - 1.9e-46 157.9 2.9 1.9e-46 157.9 2.9 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KDO27868.1 - 0.00066 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain C-C_Bond_Lyase PF15617.6 KDO27868.1 - 0.0016 17.7 0.3 0.13 11.4 0.2 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 KDO27868.1 - 0.0072 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Glyco_hydro_46 PF01374.18 KDO27868.1 - 0.1 12.2 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 HpcH_HpaI PF03328.14 KDO27869.1 - 3.5e-39 134.2 0.5 4.1e-39 134.0 0.5 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2280 PF10045.9 KDO27869.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) PEP-utilizers_C PF02896.18 KDO27869.1 - 0.086 11.9 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain PP2C PF00481.21 KDO27870.1 - 1e-42 146.6 0.0 3.5e-42 144.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Sacchrp_dh_NADP PF03435.18 KDO27871.1 - 1e-17 64.6 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Acyl_transf_3 PF01757.22 KDO27875.1 - 9.4e-18 64.4 22.5 1.3e-09 37.6 5.0 2.9 1 1 2 3 3 3 2 Acyltransferase family CCD PF07860.11 KDO27876.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 WisP family C-Terminal Region Rrp44_CSD1 PF17216.3 KDO27877.1 - 0.086 12.6 1.5 0.16 11.7 1.5 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain CTP_transf_1 PF01148.20 KDO27878.1 - 8.9e-37 127.3 27.4 6.3e-35 121.2 23.3 2.3 1 1 1 2 2 2 2 Cytidylyltransferase family DUF4145 PF13643.6 KDO27879.1 - 0.027 14.6 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) DUF86 PF01934.17 KDO27879.1 - 0.058 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF86 HEPN_Apea PF18739.1 KDO27879.1 - 0.066 13.6 0.2 0.13 12.7 0.2 1.6 1 1 0 1 1 1 0 Apea-like HEPN Peptidase_S15 PF02129.18 KDO27880.1 - 4e-42 144.7 0.3 6.7e-42 143.9 0.3 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KDO27880.1 - 5e-26 92.0 0.1 8.9e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_1 PF00561.20 KDO27880.1 - 1.2e-05 25.1 0.2 9.1e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO27880.1 - 5.4e-05 22.6 0.0 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KDO27880.1 - 0.00033 20.2 0.5 0.00094 18.7 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.14 KDO27880.1 - 0.00038 19.9 0.1 0.00059 19.2 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 KDO27880.1 - 0.055 14.1 8.7 0.39 11.3 8.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Dabb PF07876.12 KDO27881.1 - 3.2e-20 72.5 0.0 3.6e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Alpha-amylase PF00128.24 KDO27882.1 - 5.4e-71 239.9 0.0 1.5e-54 185.8 0.0 3.1 2 1 0 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KDO27882.1 - 0.028 13.5 0.0 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain ABC2_membrane PF01061.24 KDO27883.1 - 1.7e-24 86.4 22.2 2.7e-24 85.8 22.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 KDO27883.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.9 4 1 1 5 5 5 0 CDR ABC transporter ABC2_membrane PF01061.24 KDO27884.1 - 1.3e-37 129.2 22.0 1.3e-37 129.2 22.0 2.2 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.27 KDO27884.1 - 7.6e-16 58.9 0.0 1.2e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_assoc PF08370.11 KDO27884.1 - 8.9e-07 28.6 0.6 8.9e-07 28.6 0.6 2.0 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 KDO27884.1 - 5.3e-05 23.2 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KDO27884.1 - 6.5e-05 22.2 13.2 7.3e-05 22.0 12.2 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KDO27884.1 - 0.0011 18.6 0.6 0.0066 16.2 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO27884.1 - 0.0031 17.4 0.1 0.0059 16.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KDO27884.1 - 0.018 14.6 0.5 0.044 13.4 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO27884.1 - 0.018 15.4 0.1 0.051 14.0 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 KDO27884.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 KDO27884.1 - 0.19 12.2 0.1 0.32 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 KDO27884.1 - 0.24 11.3 0.7 3.8 7.5 0.3 2.5 2 0 0 2 2 2 0 CDR ABC transporter SMC_N PF02463.19 KDO27884.1 - 0.25 10.8 0.1 13 5.2 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SID-1_RNA_chan PF13965.6 KDO27884.1 - 1.2 7.4 6.1 1.9 6.8 6.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC_tran PF00005.27 KDO27885.1 - 3e-13 50.5 0.0 3.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KDO27885.1 - 0.0084 16.5 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain E1-E2_ATPase PF00122.20 KDO27887.1 - 4.8e-17 62.1 0.4 9.4e-17 61.1 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Dabb PF07876.12 KDO27888.1 - 2e-19 70.0 0.0 2.2e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Cyclin_C_2 PF16899.5 KDO27889.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain WD40 PF00400.32 KDO27890.1 - 5.8e-22 77.6 13.8 0.00019 22.1 0.2 9.6 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27890.1 - 0.00014 22.1 0.0 3.8 7.9 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KDO27890.1 - 0.0021 17.7 2.7 1.7 8.1 0.1 4.6 3 2 2 5 5 5 2 PQQ-like domain HELP PF03451.14 KDO27890.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 HELP motif IPK PF03770.16 KDO27891.1 - 2.1e-45 155.0 0.0 3.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase PQQ_2 PF13360.6 KDO27892.1 - 0.0012 18.5 1.3 0.75 9.3 0.1 2.8 2 1 1 3 3 3 2 PQQ-like domain FRG1 PF06229.12 KDO27892.1 - 0.031 14.0 0.1 7.6 6.2 0.0 3.0 3 1 1 4 4 4 0 FRG1-like domain RicinB_lectin_2 PF14200.6 KDO27892.1 - 0.12 13.1 0.2 0.12 13.1 0.2 2.7 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like PQQ_3 PF13570.6 KDO27892.1 - 0.33 11.5 5.8 9.3 6.9 0.4 4.8 4 1 1 5 5 5 0 PQQ-like domain ABC2_membrane PF01061.24 KDO27893.1 - 2.4e-65 219.9 49.9 7.4e-37 126.8 21.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO27893.1 - 5.6e-30 104.6 0.0 2.1e-15 57.4 0.1 2.2 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 KDO27893.1 - 6.8e-06 25.7 0.5 6.8e-06 25.7 0.5 3.4 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_16 PF13191.6 KDO27893.1 - 8.2e-06 26.3 0.4 0.2 12.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KDO27893.1 - 3.9e-05 23.6 0.0 0.46 10.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KDO27893.1 - 8.3e-05 22.3 1.3 0.086 12.4 0.3 3.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KDO27893.1 - 0.00017 21.5 0.5 0.011 15.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KDO27893.1 - 0.00018 21.1 3.9 0.014 15.1 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 KDO27893.1 - 0.0003 20.6 2.3 0.49 10.3 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KDO27893.1 - 0.00067 18.9 13.4 0.00067 18.9 13.4 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 KDO27893.1 - 0.012 15.9 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KDO27893.1 - 0.013 15.6 0.7 5.5 7.1 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO27893.1 - 0.054 14.0 0.0 4.8 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KDO27893.1 - 0.095 12.1 0.7 21 4.4 0.1 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO27893.1 - 0.19 12.2 0.4 0.57 10.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO27893.1 - 0.2 11.4 0.5 13 5.4 0.4 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO27893.1 - 0.22 11.9 0.2 35 4.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABC_ATPase PF09818.9 KDO27893.1 - 0.23 10.2 0.6 0.38 9.5 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class GLTP PF08718.11 KDO27894.1 - 9.3e-14 51.9 0.0 1.7e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) LRR_8 PF13855.6 KDO27894.1 - 1.1e-13 50.7 7.3 1.7e-06 27.7 0.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO27894.1 - 5.8e-10 39.3 15.6 1.9e-05 24.9 3.9 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO27894.1 - 1.6e-06 27.7 0.1 2.3e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KDO27894.1 - 4.5 7.6 7.5 65 4.0 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Ank_2 PF12796.7 KDO27895.1 - 2.3e-05 24.9 5.0 2.7e-05 24.6 0.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27895.1 - 0.0002 21.8 7.9 0.059 14.0 0.2 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO27895.1 - 0.0028 17.9 8.4 0.35 11.3 0.1 4.7 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27895.1 - 0.24 12.1 9.2 96 4.1 0.0 5.7 6 1 1 7 7 7 0 Ankyrin repeat Cyt-b5 PF00173.28 KDO27896.1 - 1.6e-10 40.9 0.0 4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase_Tyr PF07714.17 KDO27897.1 - 8e-32 110.5 0.0 3.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO27897.1 - 3e-31 108.7 0.0 9.6e-20 71.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain DUF1126 PF06565.12 KDO27900.1 - 2.5e-85 281.2 1.9 2.4e-28 98.0 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain CYYR1 PF10873.8 KDO27900.1 - 0.43 11.0 3.4 0.71 10.3 3.4 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 cNMP_binding PF00027.29 KDO27901.1 - 2.9e-09 36.9 0.1 0.006 16.6 0.0 3.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain TPR_1 PF00515.28 KDO27901.1 - 8.2e-09 34.9 2.9 0.017 14.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27901.1 - 1.5e-07 31.0 11.2 0.065 13.4 0.2 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO27901.1 - 4.3e-05 24.1 18.8 0.00048 20.7 6.3 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27901.1 - 4.5e-05 23.6 10.8 0.023 15.0 3.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat Response_reg PF00072.24 KDO27901.1 - 0.0027 17.9 0.1 0.0093 16.1 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain TPR_8 PF13181.6 KDO27901.1 - 0.023 14.9 2.7 13 6.3 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO27901.1 - 0.07 13.8 12.8 3.2 8.7 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO27901.1 - 0.57 10.4 3.0 0.47 10.7 0.4 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KDO27901.1 - 1.1 9.9 14.0 0.32 11.6 1.3 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO27901.1 - 2.3 8.8 4.3 84 3.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27901.1 - 3.3 8.8 13.5 24 6.1 0.7 5.0 2 1 2 4 4 4 0 Tetratricopeptide repeat Syntaxin_2 PF14523.6 KDO27901.1 - 7.4 7.0 16.5 1.1e+02 3.2 13.8 2.7 1 1 1 2 2 2 0 Syntaxin-like protein TPR_19 PF14559.6 KDO27902.1 - 1.4e-12 47.9 14.2 0.0039 17.7 0.7 6.7 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO27902.1 - 1.1e-11 43.9 33.4 0.014 15.4 0.0 10.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO27902.1 - 4.1e-10 40.1 10.2 0.083 13.6 0.1 6.9 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 KDO27902.1 - 5e-10 39.4 19.2 0.025 15.2 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO27902.1 - 5.3e-10 39.4 25.6 0.00011 22.4 6.5 6.2 2 2 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KDO27902.1 - 1.8e-08 34.5 18.8 0.025 14.8 1.4 7.8 5 3 3 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27902.1 - 2e-08 34.3 11.6 0.012 16.4 0.0 8.8 5 2 5 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO27902.1 - 5.4e-08 32.4 19.4 0.053 13.8 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO27902.1 - 7.6e-07 28.7 33.7 0.059 13.2 0.3 9.8 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO27902.1 - 3.7e-06 26.6 10.0 1.7 8.9 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO27902.1 - 0.001 18.5 8.6 0.19 11.1 1.3 2.9 2 1 0 2 2 2 2 MalT-like TPR region Fis1_TPR_C PF14853.6 KDO27902.1 - 0.0013 18.8 1.9 0.033 14.3 0.2 6.0 6 1 1 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 KDO27902.1 - 0.0057 16.7 21.4 0.26 11.3 6.0 5.3 3 2 2 5 5 5 3 Putative TPR-like repeat HrpB1_HrpK PF09613.10 KDO27902.1 - 0.02 14.5 0.2 2.7 7.6 0.0 3.7 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF3808 PF10300.9 KDO27902.1 - 0.03 13.1 15.5 0.12 11.0 1.2 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF3808) TPR_4 PF07721.14 KDO27902.1 - 0.069 13.8 0.6 30 5.6 0.0 4.0 5 0 0 5 5 2 0 Tetratricopeptide repeat PPR PF01535.20 KDO27902.1 - 0.086 13.1 4.2 1.5e+02 3.0 0.0 5.7 5 0 0 5 5 5 0 PPR repeat TPR_21 PF09976.9 KDO27902.1 - 0.19 11.4 12.6 0.3 10.8 3.0 3.9 2 2 1 4 4 4 0 Tetratricopeptide repeat-like domain Rubrerythrin PF02915.17 KDO27902.1 - 0.23 11.8 5.7 0.49 10.8 1.4 3.2 3 0 0 3 3 3 0 Rubrerythrin Pkinase_Tyr PF07714.17 KDO27905.1 - 4.7e-22 78.5 0.0 2.9e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO27905.1 - 1.5e-12 47.5 0.0 2.9e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Protocadherin PF08374.11 KDO27905.1 - 0.16 11.9 0.2 0.26 11.3 0.2 1.2 1 0 0 1 1 1 0 Protocadherin LRR_8 PF13855.6 KDO27905.1 - 0.21 11.4 2.5 0.46 10.3 2.5 1.6 1 0 0 1 1 1 0 Leucine rich repeat GlcNAc PF11397.8 KDO27906.1 - 7.3e-48 163.8 0.3 1.1e-39 137.0 0.3 2.3 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Gal_Lectin PF02140.18 KDO27907.1 - 4.5e-30 103.9 4.1 6.5e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain PRIMA1 PF16101.5 KDO27907.1 - 5.6 7.0 7.4 10 6.2 7.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Gal_Lectin PF02140.18 KDO27909.1 - 3.3e-30 104.3 9.9 3.2e-16 59.5 0.8 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain Fringe PF02434.16 KDO27911.1 - 5.4e-13 49.0 0.4 7.8e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KDO27911.1 - 0.013 15.4 2.8 0.027 14.3 2.6 1.7 1 1 1 2 2 2 0 Galactosyltransferase DUF775 PF05603.12 KDO27912.1 - 2.3e-39 135.0 0.5 3.1e-38 131.3 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Asp PF00026.23 KDO27912.1 - 2.5e-32 112.6 0.0 2.8e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO27912.1 - 1.3e-06 28.8 0.3 2.4e-05 24.7 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO27912.1 - 5.6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal NrfD_2 PF14589.6 KDO27912.1 - 0.0082 16.2 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Polysulfide reductase EphA2_TM PF14575.6 KDO27912.1 - 0.037 14.9 0.1 0.073 14.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KDO27912.1 - 0.077 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4381 PF14316.6 KDO27912.1 - 0.14 12.4 0.2 0.27 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LRR19-TM PF15176.6 KDO27912.1 - 0.23 11.5 0.1 0.44 10.6 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain B56 PF01603.20 KDO27913.1 - 1.9e-164 547.6 1.2 2.3e-164 547.3 1.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) E1-E2_ATPase PF00122.20 KDO27914.1 - 2.1e-17 63.2 0.0 1.7e-16 60.3 0.0 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KDO27914.1 - 5.7e-14 52.9 0.0 5.1e-09 36.7 0.0 2.5 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ost5 PF05251.12 KDO27914.1 - 0.75 10.1 9.3 0.26 11.6 1.7 4.0 2 1 1 3 3 3 0 Oligosaccharyltransferase subunit 5 LIDHydrolase PF10230.9 KDO27915.1 - 2.7e-52 178.0 0.1 3.2e-52 177.7 0.1 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KDO27915.1 - 1.7e-09 37.3 0.8 2.8e-09 36.6 0.6 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO27915.1 - 1.1e-08 35.0 0.3 1.7e-08 34.4 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO27915.1 - 5.5e-07 30.4 5.4 9.8e-07 29.6 5.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KDO27915.1 - 0.00051 19.9 0.2 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase Esterase PF00756.20 KDO27915.1 - 0.006 16.3 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 KDO27915.1 - 0.12 12.2 0.2 0.27 11.1 0.2 1.6 1 1 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KDO27915.1 - 1.4 8.6 3.5 0.47 10.1 0.1 1.8 3 0 0 3 3 3 0 PGAP1-like protein Sec1 PF00995.23 KDO27916.1 - 4.1e-12 46.1 0.0 2.4e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Sec1 family CAMSAP_CKK PF08683.11 KDO27917.1 - 6.7e-25 87.6 0.0 1.2e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated DUF3280 PF11684.8 KDO27918.1 - 0.21 12.0 3.7 0.13 12.6 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) RhoGAP PF00620.27 KDO27919.1 - 0.0035 17.2 0.1 0.017 15.0 0.0 2.1 2 1 0 2 2 2 1 RhoGAP domain BK_channel_a PF03493.18 KDO27920.1 - 4.8e-21 74.8 0.1 5.1e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KDO27920.1 - 4.1e-19 68.8 5.6 7.1e-19 68.0 5.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO27920.1 - 1.3e-14 53.9 0.5 3.1e-14 52.7 0.5 1.6 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 KDO27920.1 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel TrkA_N PF02254.18 KDO27920.1 - 0.14 12.5 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain SLC35F PF06027.12 KDO27921.1 - 2.8e-57 194.5 15.6 3.5e-57 194.2 15.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KDO27921.1 - 1.3e-06 27.6 0.3 1.3e-06 27.6 0.3 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO27921.1 - 2.3e-05 24.6 27.1 3.3e-05 24.1 11.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 KDO27921.1 - 0.0063 15.7 9.4 0.043 12.9 9.4 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA UAA PF08449.11 KDO27921.1 - 0.078 12.2 10.2 0.52 9.5 10.2 1.9 1 1 0 1 1 1 0 UAA transporter family Rtf2 PF04641.12 KDO27922.1 - 1.8 7.9 22.1 2.6 7.4 22.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Med19 PF10278.9 KDO27922.1 - 1.9 8.4 26.9 2.9 7.8 26.9 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zip PF02535.22 KDO27922.1 - 3.7 6.7 8.0 3.7 6.7 8.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.11 KDO27922.1 - 5.3 5.8 14.7 6.2 5.6 14.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RR_TM4-6 PF06459.12 KDO27922.1 - 5.4 6.8 21.1 6.8 6.4 21.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1115 PF06544.12 KDO27923.1 - 3.4e-10 40.2 0.0 4.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 KDO27923.1 - 1.5e-05 25.3 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain UvrC_HhH_N PF08459.11 KDO27923.1 - 0.052 13.5 0.0 0.5 10.3 0.1 2.0 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal PALP PF00291.25 KDO27924.1 - 5.6e-32 111.3 0.0 7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LRR_9 PF14580.6 KDO27925.1 - 1.1e-08 34.8 0.3 2.2e-08 33.8 0.3 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KDO27925.1 - 1.2e-07 31.4 6.0 0.0027 17.4 0.5 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO27925.1 - 1e-05 25.8 5.9 0.011 16.1 0.4 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO27925.1 - 0.0035 17.3 2.6 4.2 7.7 0.2 3.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KDO27925.1 - 0.59 10.9 3.5 11 7.1 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Ribosomal_60s PF00428.19 KDO27925.1 - 7.3 7.3 25.7 0.28 11.8 19.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C3HC4_2 PF13923.6 KDO27926.1 - 2.3e-10 40.1 10.4 7e-10 38.6 10.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO27926.1 - 1.8e-09 37.3 9.2 1.8e-09 37.3 9.2 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO27926.1 - 5.8e-08 32.5 7.1 1.4e-07 31.3 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO27926.1 - 3.3e-07 30.5 8.4 3.3e-07 30.5 8.4 2.2 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO27926.1 - 6e-07 29.2 10.4 6e-07 29.2 10.4 2.2 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO27926.1 - 3.4e-06 26.9 9.9 3.4e-06 26.9 9.9 2.3 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO27926.1 - 1.6e-05 24.8 7.0 5.2e-05 23.2 7.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 KDO27926.1 - 5.4e-05 23.0 2.3 0.00015 21.6 2.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KDO27926.1 - 0.00019 21.7 6.2 0.00066 19.9 6.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 KDO27926.1 - 0.0018 18.3 3.8 0.0068 16.5 3.8 2.0 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_10 PF16685.5 KDO27926.1 - 0.013 15.6 7.5 0.042 14.0 7.5 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KDO27926.1 - 0.014 15.5 7.3 0.041 14.1 7.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3251 PF11622.8 KDO27926.1 - 0.031 13.9 4.0 0.06 13.0 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) zf-ANAPC11 PF12861.7 KDO27926.1 - 0.24 11.5 3.7 0.66 10.1 3.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KDO27926.1 - 0.32 10.8 12.9 0.022 14.6 7.4 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KDO27926.1 - 0.48 10.2 5.5 1.6 8.5 5.5 2.0 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 KDO27926.1 - 0.82 9.8 8.2 0.7 10.0 4.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) A2L_zn_ribbon PF08792.10 KDO27926.1 - 3.2 7.6 6.6 12 5.7 6.6 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain DcrB PF08786.11 KDO27926.1 - 5.4 7.1 15.4 0.84 9.7 0.7 4.0 3 2 0 3 3 3 0 DcrB Syntaxin_2 PF14523.6 KDO27926.1 - 5.7 7.4 14.8 7.3 7.0 0.1 4.3 3 1 1 4 4 4 0 Syntaxin-like protein DUF2993 PF11209.8 KDO27928.1 - 0.028 14.6 2.4 0.05 13.8 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) XhlA PF10779.9 KDO27928.1 - 0.078 13.2 5.4 2.6 8.3 0.1 3.6 4 0 0 4 4 4 0 Haemolysin XhlA Csm1_N PF18504.1 KDO27928.1 - 0.083 13.2 8.6 0.46 10.9 3.2 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 KDO27928.1 - 0.2 11.5 2.1 0.77 9.7 2.1 2.1 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc29 PF17082.5 KDO27928.1 - 0.53 10.1 3.7 9.6 6.0 0.7 2.6 2 1 1 3 3 3 0 Spindle Pole Component 29 Tropomyosin_1 PF12718.7 KDO27928.1 - 0.78 9.9 14.2 0.54 10.4 3.9 3.0 1 1 1 2 2 2 0 Tropomyosin like Fib_alpha PF08702.10 KDO27928.1 - 0.85 9.8 6.5 1.1 9.5 1.0 3.1 2 1 2 5 5 5 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 KDO27928.1 - 3.1 7.9 14.4 13 5.9 6.5 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ABC_tran_Xtn PF12848.7 KDO27928.1 - 3.2 7.8 6.6 1.1 9.3 3.1 2.2 2 0 0 2 2 2 0 ABC transporter SlyX PF04102.12 KDO27928.1 - 4 8.1 19.0 0.19 12.3 0.9 5.1 3 1 1 5 5 5 0 SlyX TMF_DNA_bd PF12329.8 KDO27928.1 - 4.7 7.3 8.6 0.67 10.0 0.8 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 KDO27932.1 - 0.23 11.4 6.3 3.5 7.6 0.0 5.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat TRAF_BIRC3_bd PF16673.5 KDO27932.1 - 5.5 6.9 14.4 6 6.7 0.5 5.3 5 2 0 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain DUF4250 PF14056.6 KDO27932.1 - 5.5 7.0 5.7 4.8 7.2 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Pro-kuma_activ PF09286.11 KDO27933.1 - 1.6e-20 73.9 0.0 4.2e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KDO27933.1 - 4.9e-07 29.3 0.6 8.2e-07 28.6 0.6 1.3 1 0 0 1 1 1 1 Subtilase family DUF1242 PF06842.12 KDO27933.1 - 0.094 12.5 1.8 0.27 11.1 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) DUF1459 PF07312.11 KDO27933.1 - 0.34 11.2 2.8 1.2 9.4 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Pkinase PF00069.25 KDO27934.1 - 4e-71 239.5 0.0 6.2e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27934.1 - 3.2e-39 134.8 0.0 5.5e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27934.1 - 2e-05 24.1 0.1 9.6e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Arb2 PF09757.9 KDO27934.1 - 4.6e-05 22.7 0.0 7.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain FTA2 PF13095.6 KDO27934.1 - 0.00051 19.7 0.2 0.0099 15.5 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO27934.1 - 0.0043 16.1 0.1 0.0068 15.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO27934.1 - 0.033 13.0 0.1 0.083 11.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Macro PF01661.21 KDO27935.1 - 4.2e-15 55.8 0.0 7.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain Ribosomal_L28e PF01778.17 KDO27936.1 - 9.2e-27 94.1 2.2 1.3e-26 93.6 2.2 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Cupin_8 PF13621.6 KDO27938.1 - 1.1e-24 87.6 0.1 2.1e-24 86.6 0.1 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KDO27938.1 - 1.1e-16 61.3 0.1 1.7e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase FYVE PF01363.21 KDO27939.1 - 5.8e-12 45.6 11.7 1.3e-11 44.4 11.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27939.1 - 0.034 14.4 6.8 0.075 13.2 6.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 KDO27939.1 - 0.18 11.8 7.5 0.4 10.7 7.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.21 KDO27940.1 - 1.4e-11 44.3 13.7 2.6e-11 43.5 13.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27940.1 - 3.8 7.7 8.8 9.8 6.4 8.8 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_108 PF05838.12 KDO27942.1 - 0.09 13.3 0.2 0.22 12.0 0.1 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase 108 Trypan_PARP PF05887.11 KDO27942.1 - 1.7 8.6 13.7 0.034 14.1 6.8 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF2909 PF11137.8 KDO27944.1 - 0.018 15.0 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) MARVEL PF01284.23 KDO27944.1 - 0.032 14.3 0.3 0.043 13.8 0.3 1.2 1 0 0 1 1 1 0 Membrane-associating domain Stevor PF17410.2 KDO27944.1 - 0.084 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3995 PF13160.6 KDO27944.1 - 0.22 11.9 7.0 0.25 11.7 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) MerC PF03203.14 KDO27944.1 - 0.38 11.2 5.8 0.25 11.8 4.1 1.6 1 1 1 2 2 2 0 MerC mercury resistance protein DUF202 PF02656.15 KDO27944.1 - 1.4 9.4 5.0 13 6.3 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) BORCS7 PF16088.5 KDO27945.1 - 0.052 13.8 2.0 1.3 9.4 0.4 2.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 NPV_P10 PF05531.12 KDO27945.1 - 3.4 8.2 8.2 8.1 7.0 0.0 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FYVE PF01363.21 KDO27946.1 - 9.8e-12 44.8 12.6 2e-11 43.9 12.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger NOB1_Zn_bind PF08772.11 KDO27946.1 - 0.026 14.7 6.8 0.026 14.7 6.8 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like 2OG-FeII_Oxy_3 PF13640.6 KDO27947.1 - 6e-17 62.3 0.0 1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 KDO27947.1 - 9.5e-11 41.6 11.6 1.9e-10 40.7 11.6 1.5 1 0 0 1 1 1 1 MYND finger 2OG-FeII_Oxy_4 PF13661.6 KDO27947.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KDO27947.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) zf-C6H2 PF15801.5 KDO27947.1 - 0.23 11.8 6.0 0.53 10.6 6.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DiS_P_DiS PF06750.13 KDO27948.1 - 0.14 12.3 0.3 0.19 11.9 0.3 1.3 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain CNDH2_C PF16858.5 KDO27949.1 - 4.7e-42 144.9 0.0 1.5e-41 143.2 0.0 1.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 KDO27949.1 - 1.1e-19 70.7 0.1 2e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal 2-Hacid_dh_C PF02826.19 KDO27950.1 - 8e-59 198.0 0.0 1.4e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO27950.1 - 1.4e-26 92.7 0.0 1.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CBP_BcsO PF17037.5 KDO27950.1 - 0.00055 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsO NAD_binding_2 PF03446.15 KDO27950.1 - 0.0037 17.4 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 KDO27950.1 - 0.0039 18.0 0.0 0.0085 16.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold VOMI PF03762.17 KDO27950.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) IlvN PF07991.12 KDO27950.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1892 PF08987.10 KDO27950.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) zf-C2H2 PF00096.26 KDO27951.1 - 3.3e-10 39.9 20.9 0.0026 18.1 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO27951.1 - 5.4e-09 36.1 19.4 0.0054 17.5 0.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO27951.1 - 3.1e-07 30.5 0.8 3.1e-07 30.5 0.8 3.6 4 0 0 4 4 4 2 Zinc-finger double domain DUF5557 PF17712.1 KDO27951.1 - 0.028 14.4 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5557) zf-met PF12874.7 KDO27951.1 - 0.084 13.3 1.0 0.084 13.3 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KDO27951.1 - 0.19 12.1 11.0 0.32 11.3 3.5 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KDO27951.1 - 0.23 11.8 5.1 0.53 10.6 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KDO27951.1 - 7.2 6.6 13.7 11 6.1 0.3 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Cyclin_N PF00134.23 KDO27952.1 - 1.4e-08 34.5 0.0 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KDO27952.1 - 0.023 14.7 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cnd2 PF05786.14 KDO27953.1 - 0.0065 15.2 0.7 0.0091 14.7 0.7 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 APG17 PF04108.12 KDO27953.1 - 0.03 13.4 4.1 0.022 13.9 2.0 1.7 1 1 1 2 2 2 0 Autophagy protein Apg17 Lzipper-MIP1 PF14389.6 KDO27953.1 - 0.81 10.0 4.5 14 6.0 0.6 2.5 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Methyltransf_31 PF13847.6 KDO27954.1 - 7.6e-10 38.8 0.0 9.8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO27954.1 - 1.4e-08 35.3 0.0 2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO27954.1 - 2.6e-07 31.3 0.0 4.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KDO27954.1 - 3.7e-07 30.0 0.0 5.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 KDO27954.1 - 1.8e-06 28.6 0.0 2.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO27954.1 - 0.00085 18.7 0.0 0.0013 18.2 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KDO27954.1 - 0.0034 17.2 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 KDO27954.1 - 0.042 13.0 0.1 0.6 9.3 0.0 2.0 1 1 1 2 2 2 0 N2227-like protein FYVE_2 PF02318.16 KDO27957.1 - 1.7e-05 25.0 9.5 3.3e-05 24.1 9.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO27957.1 - 0.00079 19.5 13.3 0.0026 17.9 13.2 1.8 1 1 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO27957.1 - 0.49 10.8 11.2 1.2 9.6 11.2 1.7 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 KDO27957.1 - 3.6 7.6 9.3 7.8 6.5 9.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KDO27957.1 - 5.5 6.9 8.9 11 6.0 8.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain VPS9 PF02204.18 KDO27959.1 - 1.2e-16 60.8 0.1 3.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 KDO27959.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 PX domain DnaI_N PF07319.11 KDO27959.1 - 0.06 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Y_phosphatase2 PF03162.13 KDO27960.1 - 3.7e-43 147.0 0.0 4.6e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KDO27960.1 - 0.033 14.2 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Aminotran_1_2 PF00155.21 KDO27961.1 - 2.2e-22 79.7 0.0 2.9e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KDO27961.1 - 3.5e-08 32.7 0.0 4.6e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Renin_r PF07850.14 KDO27962.1 - 5.6e-05 23.7 0.6 0.00012 22.6 0.5 1.6 1 1 0 1 1 1 1 Renin receptor-like protein DUF3394 PF11874.8 KDO27962.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) M20_dimer PF07687.14 KDO27963.1 - 0.0036 17.2 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain CSRNP_N PF16019.5 KDO27964.1 - 0.0004 20.4 2.1 0.00089 19.2 0.0 1.9 1 1 1 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus FYVE PF01363.21 KDO27965.1 - 2.1e-10 40.6 13.6 5.2e-10 39.3 13.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO27965.1 - 0.00036 20.7 4.6 0.00075 19.7 4.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 KDO27965.1 - 0.0041 17.3 7.0 0.013 15.8 7.0 1.8 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 KDO27965.1 - 0.013 15.4 11.4 0.019 14.9 7.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KDO27965.1 - 0.014 15.4 9.3 0.11 12.6 9.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Baculo_IE-1 PF05290.11 KDO27965.1 - 0.032 14.2 1.6 0.088 12.8 1.6 1.8 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 KDO27965.1 - 0.091 13.1 14.8 0.32 11.4 14.8 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KDO27965.1 - 0.72 9.8 10.9 2.1 8.3 10.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GST_N_3 PF13417.6 KDO27966.1 - 2.1e-10 40.9 0.0 4.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO27966.1 - 1.1e-07 32.1 0.0 2.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO27966.1 - 4.3e-07 30.2 0.5 9.7e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO27966.1 - 4.5e-05 23.4 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO27966.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO27966.1 - 0.023 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GlcNAc PF11397.8 KDO27967.1 - 2.2e-52 178.7 0.0 1.6e-45 156.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 KDO27967.1 - 0.0083 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 GlcNAc PF11397.8 KDO27968.1 - 1.3e-34 120.3 0.2 1.6e-17 64.0 0.1 3.3 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 KDO27969.1 - 1.3e-46 159.7 0.0 1.8e-38 132.9 0.1 2.3 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Cellulase PF00150.18 KDO27970.1 - 3e-30 105.6 0.4 4e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) G-patch_2 PF12656.7 KDO27972.1 - 1.1e-17 63.9 0.4 3e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 G-patch domain PRP38_assoc PF12871.7 KDO27972.1 - 0.053 14.1 32.7 0.096 13.3 32.7 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Kinesin PF00225.23 KDO27973.1 - 4e-115 384.3 0.0 4e-115 384.3 0.0 1.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KDO27973.1 - 5.6e-24 84.8 0.1 3.1e-23 82.4 0.0 2.3 3 1 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 KDO27973.1 - 0.3 11.2 15.4 0.047 13.8 9.4 2.5 2 1 1 3 3 3 0 Kinesin-associated AAA_22 PF13401.6 KDO27973.1 - 4.2 7.6 0.0 4.2 7.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 KDO27974.1 - 6.6e-10 39.5 0.4 5.1e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO27974.1 - 1e-08 35.6 0.7 3e-05 24.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) WW PF00397.26 KDO27974.1 - 4.9e-08 32.9 0.4 8.2e-08 32.2 0.4 1.3 1 0 0 1 1 1 1 WW domain Ank_5 PF13857.6 KDO27974.1 - 1.4e-06 28.5 0.3 0.00048 20.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO27974.1 - 0.00013 22.1 2.9 0.047 14.2 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KDO27974.1 - 0.1 13.1 8.5 1 9.9 0.5 4.2 4 0 0 4 4 4 0 Ankyrin repeat PH PF00169.29 KDO27975.1 - 0.00014 22.3 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KDO27975.1 - 0.0062 17.0 0.0 0.039 14.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KDO27975.1 - 0.012 15.9 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO27975.1 - 0.065 13.8 0.0 0.094 13.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) PH_13 PF16652.5 KDO27975.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Isochorismatase PF00857.20 KDO27976.1 - 8.6e-24 84.7 0.0 1.7e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family PA PF02225.22 KDO27976.1 - 4.7e-13 49.0 0.1 1.1e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 PA domain CSN8_PSD8_EIF3K PF10075.9 KDO27978.1 - 1.6e-14 54.1 0.1 2.2e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF639 PF04842.12 KDO27978.1 - 0.045 13.2 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) SMC_N PF02463.19 KDO27979.1 - 3.5e-79 265.3 0.0 3.4e-78 262.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KDO27979.1 - 1.5e-23 83.3 0.0 5.6e-23 81.5 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KDO27979.1 - 1.1e-13 51.7 3.0 1.5e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO27979.1 - 1.3e-10 42.1 9.7 1.3e-10 42.1 9.7 5.7 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 KDO27979.1 - 6.7e-09 35.9 11.7 6.7e-09 35.9 11.7 3.6 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KDO27979.1 - 9e-05 22.1 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KDO27979.1 - 0.06 13.6 0.4 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PIN7 PF18475.1 KDO27979.1 - 0.35 11.5 3.3 3.4 8.3 0.0 3.9 4 0 0 4 4 4 0 PIN domain AAA_16 PF13191.6 KDO27979.1 - 0.94 9.8 4.0 4.9 7.5 0.0 3.8 3 0 0 3 3 3 0 AAA ATPase domain Filament PF00038.21 KDO27979.1 - 2.4 7.6 102.1 0.038 13.6 33.2 6.0 3 2 4 7 7 7 0 Intermediate filament protein UTP15_C PF09384.10 KDO27980.1 - 1.2e-37 128.8 0.0 1.9e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KDO27980.1 - 1.2e-27 95.6 12.6 4.9e-07 30.3 0.1 6.8 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO27980.1 - 4e-12 46.3 0.4 0.0018 18.5 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO27980.1 - 0.00012 20.9 1.6 0.049 12.3 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KDO27980.1 - 0.0063 15.9 0.0 3.3 6.9 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 KDO27980.1 - 0.072 12.7 0.2 2.8 7.4 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain Aconitase_B_N PF11791.8 KDO27981.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Aconitate B N-terminal domain zf-CCCH PF00642.24 KDO27982.1 - 4.5e-11 42.4 20.8 0.00063 19.6 2.5 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO27982.1 - 4e-07 30.7 16.6 0.00011 22.9 0.2 4.1 1 1 3 4 4 4 3 Torus domain zf_CCCH_4 PF18345.1 KDO27982.1 - 2.8e-06 27.2 25.1 0.0069 16.4 1.0 5.1 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH_3 PF15663.5 KDO27982.1 - 6.5e-06 26.3 13.3 0.0028 17.9 4.2 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 KDO27982.1 - 0.00099 18.8 13.6 0.064 13.0 0.3 4.3 4 0 0 4 4 4 2 Putative zinc-finger domain VPS9 PF02204.18 KDO27983.1 - 1.4e-10 41.3 0.0 3.5e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 KDO27983.1 - 8.7e-08 32.1 0.1 2.1e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 PX domain CUE PF02845.16 KDO27983.1 - 4.1e-05 23.2 0.1 0.00018 21.2 0.0 2.1 2 0 0 2 2 2 1 CUE domain DUF2723 PF11028.8 KDO27984.1 - 6.1e-31 107.6 6.5 6.1e-31 107.6 6.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) FYVE PF01363.21 KDO27985.1 - 9.3e-14 51.3 10.6 1.2e-12 47.8 12.2 2.1 2 1 0 2 2 2 1 FYVE zinc finger START PF01852.19 KDO27985.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.7 1 0 0 1 1 1 0 START domain FYVE_2 PF02318.16 KDO27985.1 - 0.82 9.9 9.2 1.2 9.4 8.5 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Glyco_transf_41 PF13844.6 KDO27986.1 - 1.9e-16 59.6 0.0 4.4e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 Glyco_trans_1_4 PF13692.6 KDO27986.1 - 0.00017 22.0 0.5 0.00047 20.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_1 PF00515.28 KDO27986.1 - 0.031 14.1 0.3 5 7.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO27986.1 - 0.25 11.7 3.2 12 6.2 0.3 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO27986.1 - 3.9 8.6 8.8 0.78 10.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO27987.1 - 9.8e-69 231.6 0.0 1.1e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO27987.1 - 1.9e-30 106.0 0.0 2.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO27987.1 - 7.4e-09 35.3 0.0 3.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO27987.1 - 4.9e-06 26.0 0.1 8.3e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO27987.1 - 0.00021 21.0 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KDO27987.1 - 0.00048 19.2 0.0 0.0012 17.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO27987.1 - 0.058 13.3 0.1 0.17 11.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 KDO27988.1 - 1.9e-08 34.3 0.1 3e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO27988.1 - 0.18 12.1 0.4 0.3 11.4 0.4 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain SNARE PF05739.19 KDO27989.1 - 1.8e-12 47.1 0.1 4.4e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KDO27989.1 - 0.00056 19.6 5.3 0.054 13.2 0.2 2.3 2 0 0 2 2 2 2 Syntaxin Cellulase PF00150.18 KDO27990.1 - 3.3e-21 75.9 0.1 4.4e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lipin_N PF04571.14 KDO27991.1 - 3.5e-15 55.8 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region LNS2 PF08235.13 KDO27991.1 - 1e-13 51.3 0.0 2.9e-05 23.6 0.0 3.2 2 2 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.5 KDO27991.1 - 4.5e-05 23.5 0.0 7.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain PQQ_3 PF13570.6 KDO27993.1 - 0.28 11.7 5.7 1.4 9.5 0.1 4.1 4 1 0 4 4 4 0 PQQ-like domain Dcc1 PF09724.9 KDO27994.1 - 6.3e-67 226.2 0.2 7.3e-67 226.0 0.2 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 GFO_IDH_MocA PF01408.22 KDO27994.1 - 0.02 15.7 0.0 0.057 14.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L18A PF01775.17 KDO27995.1 - 2.1e-52 176.3 0.2 3.7e-52 175.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A W2 PF02020.18 KDO27995.1 - 2.6e-12 46.7 0.8 2.6e-12 46.7 0.8 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KDO27995.1 - 5e-11 42.6 0.1 8.4e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KDO27995.1 - 9.6e-06 25.1 13.9 0.0077 15.9 2.5 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KDO27995.1 - 0.00056 20.3 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KDO27995.1 - 0.018 13.2 0.4 0.04 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KDO27995.1 - 5.9 6.7 8.6 10 6.0 0.5 3.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase LRR_8 PF13855.6 KDO27996.1 - 1.4e-07 31.1 7.4 0.028 14.2 0.6 4.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KDO27996.1 - 0.00095 19.4 5.5 0.32 11.7 0.6 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 KDO27996.1 - 0.018 15.5 13.2 0.21 12.1 1.8 5.1 2 1 4 6 6 6 0 Leucine Rich repeats (2 copies) DSPc PF00782.20 KDO27997.1 - 3.3e-16 59.3 0.0 4.1e-11 42.8 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO27997.1 - 0.009 16.0 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO27997.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UPF0258 PF06789.12 KDO27997.1 - 0.14 12.3 0.2 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) C2 PF00168.30 KDO27998.1 - 3e-12 46.7 0.0 5.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ank_3 PF13606.6 KDO27998.1 - 0.029 14.9 0.0 0.091 13.4 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat TMEM43 PF07787.12 KDO27999.1 - 9.8e-36 123.4 0.0 1.4e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 43 Sina PF03145.16 KDO28000.1 - 0.0053 16.7 0.6 0.0085 16.1 0.6 1.3 1 0 0 1 1 1 1 Seven in absentia protein family DUF3629 PF12302.8 KDO28000.1 - 0.076 12.4 0.8 0.095 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Dicty_REP PF05086.12 KDO28002.1 - 0.056 11.4 3.0 0.063 11.3 3.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KDO28002.1 - 0.18 11.8 1.4 0.27 11.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 KDO28003.1 - 2.7e-16 59.9 14.1 6.7e-10 39.4 2.8 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28003.1 - 1.1e-15 57.5 4.5 3.7e-09 36.7 1.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28003.1 - 1.2e-09 37.6 3.0 0.00016 21.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KDO28003.1 - 3.7e-09 37.0 1.4 0.00064 20.2 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO28003.1 - 0.00014 22.2 9.7 0.068 13.6 0.3 3.5 4 0 0 4 4 4 2 Ankyrin repeat Fer4_23 PF18009.1 KDO28003.1 - 0.47 10.9 0.0 0.47 10.9 0.0 2.7 3 0 0 3 3 3 0 4Fe-4S iron-sulfur cluster binding domain SR-25 PF10500.9 KDO28004.1 - 0.65 9.6 10.4 0.95 9.0 10.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HAT_KAT11 PF08214.11 KDO28005.1 - 1.8e-20 73.5 0.1 3.6e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 KDO28005.1 - 1.8e-13 50.3 0.0 3.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KDO28005.1 - 0.0013 18.6 3.2 0.0013 18.6 3.2 3.7 3 1 0 3 3 3 1 PHD-finger UEV PF05743.13 KDO28005.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 UEV domain F5_F8_type_C PF00754.25 KDO28006.1 - 9.7e-05 22.5 0.2 0.00013 22.1 0.2 1.2 1 0 0 1 1 1 1 F5/8 type C domain TMEM89 PF15098.6 KDO28006.1 - 0.092 12.9 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 TMEM89 protein family ABC_membrane PF00664.23 KDO28007.1 - 4.2e-105 351.3 25.2 4.2e-53 180.8 7.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO28007.1 - 5.4e-70 234.2 0.0 8.4e-35 120.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO28007.1 - 7.6e-11 41.9 4.5 0.00097 18.6 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO28007.1 - 9.1e-08 32.7 1.3 0.0053 17.1 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO28007.1 - 4.1e-07 29.6 1.6 0.02 14.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KDO28007.1 - 5.5e-06 25.8 0.2 0.044 13.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KDO28007.1 - 5.7e-06 26.7 1.3 0.043 14.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KDO28007.1 - 1e-05 25.4 0.0 0.19 11.4 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain G-alpha PF00503.20 KDO28007.1 - 8.9e-05 21.8 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 KDO28007.1 - 0.0001 22.5 0.9 0.16 12.1 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 KDO28007.1 - 0.00011 22.1 1.8 2.1 8.0 0.1 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 KDO28007.1 - 0.0002 21.3 0.3 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 KDO28007.1 - 0.00037 20.1 1.0 0.1 12.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 KDO28007.1 - 0.00043 20.2 0.1 1.1 9.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KDO28007.1 - 0.00047 19.9 2.0 0.35 10.6 0.3 3.4 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KDO28007.1 - 0.0029 17.9 1.3 0.5 10.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KDO28007.1 - 0.0037 17.0 0.0 0.52 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO28007.1 - 0.004 17.7 0.1 0.32 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KDO28007.1 - 0.0042 17.3 5.0 3.2 8.1 0.2 4.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO28007.1 - 0.0093 16.1 0.0 2.8 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KDO28007.1 - 0.011 15.2 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KDO28007.1 - 0.018 15.1 0.8 2.3 8.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 KDO28007.1 - 0.023 13.5 0.1 0.023 13.5 0.1 2.8 4 0 0 4 4 3 0 Predicted ATPase of the ABC class Pox_A32 PF04665.12 KDO28007.1 - 0.074 12.5 0.8 13 5.1 0.1 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_17 PF13207.6 KDO28007.1 - 0.1 13.0 0.1 39 4.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KDO28007.1 - 0.1 12.0 0.0 5.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KDO28007.1 - 0.12 12.2 0.3 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KDO28007.1 - 0.13 11.6 1.4 6.6 6.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KDO28007.1 - 0.17 12.0 0.4 6.6 6.9 0.1 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KDO28007.1 - 1.5 8.7 3.8 41 4.0 0.1 3.4 4 0 0 4 4 4 0 NTPase ABC_membrane PF00664.23 KDO28008.1 - 3.7e-40 138.3 1.3 5.2e-40 137.8 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region NMD3 PF04981.13 KDO28008.1 - 1.3e-06 28.1 1.0 2.1e-06 27.4 0.3 1.7 2 0 0 2 2 2 1 NMD3 family DUF981 PF06168.11 KDO28008.1 - 0.045 13.7 0.1 0.045 13.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF981) DUF2852 PF11014.8 KDO28008.1 - 0.16 12.1 3.7 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) ELMO_CED12 PF04727.13 KDO28011.1 - 1.9e-09 37.9 0.0 3.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DIX PF00778.17 KDO28011.1 - 0.00029 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 DIX domain DUF480 PF04337.12 KDO28011.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 DUF4205 PF13898.6 KDO28012.1 - 2.6e-89 299.6 0.0 3.7e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Myb_DNA-bind_6 PF13921.6 KDO28012.1 - 9.6e-07 29.0 0.3 1.8e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO28012.1 - 0.00037 20.6 0.2 0.00081 19.5 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 KDO28013.1 - 1.2e-25 89.2 16.2 5.6e-06 27.0 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28013.1 - 4.4e-17 62.1 5.3 2.4e-06 27.7 0.2 4.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO28013.1 - 1.9e-07 31.1 0.0 0.011 15.6 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KDO28013.1 - 0.0039 16.2 0.7 7.8 5.4 0.2 3.6 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO28013.1 - 0.023 13.3 5.1 1 7.9 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KDO28013.1 - 0.027 13.3 0.0 0.95 8.1 0.0 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PALB2_WD40 PF16756.5 KDO28013.1 - 0.65 8.9 6.4 2.1 7.2 0.1 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Metallophos PF00149.28 KDO28014.1 - 3.4e-15 57.1 0.4 5.3e-15 56.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SPOUT_MTase PF02590.17 KDO28014.1 - 0.086 12.8 0.0 0.54 10.2 0.0 2.2 3 0 0 3 3 3 0 Predicted SPOUT methyltransferase UCH PF00443.29 KDO28015.1 - 1.9e-43 148.9 0.0 5.5e-37 127.7 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO28015.1 - 3.3e-21 76.2 0.7 5.7e-19 68.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Paired_CXXCH_1 PF09699.10 KDO28015.1 - 0.013 15.2 0.3 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) CAS_CSE1 PF03378.15 KDO28015.1 - 0.029 12.9 0.0 0.046 12.2 0.0 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus CCP_MauG PF03150.14 KDO28015.1 - 0.1 13.3 0.1 0.67 10.6 0.0 2.2 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase NapB PF03892.14 KDO28015.1 - 0.12 12.3 0.5 0.29 11.2 0.5 1.6 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Cytochrome_C7 PF14522.6 KDO28015.1 - 0.41 10.7 3.7 1.8 8.6 2.9 2.1 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Clat_adaptor_s PF01217.20 KDO28016.1 - 8.2e-44 149.0 3.5 9e-44 148.9 3.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 KDO28016.1 - 0.015 16.0 1.4 0.54 11.0 0.6 2.8 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox AAA_11 PF13086.6 KDO28017.1 - 2.3e-66 224.3 0.0 3.9e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KDO28017.1 - 9.1e-60 201.7 0.0 2.5e-59 200.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO28017.1 - 1e-11 44.9 0.0 2.5e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KDO28017.1 - 9e-09 35.4 0.0 0.025 14.3 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KDO28017.1 - 4.8e-07 30.2 0.1 0.00052 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KDO28017.1 - 1.7e-05 25.1 0.0 0.00028 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KDO28017.1 - 0.00057 19.9 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KDO28017.1 - 0.0006 18.9 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KDO28017.1 - 0.0035 17.8 0.0 0.01 16.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KDO28017.1 - 0.0066 15.7 0.1 3.3 6.8 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KDO28017.1 - 0.011 16.2 1.1 0.038 14.4 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain PhoH PF02562.16 KDO28017.1 - 0.019 14.4 0.1 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 KDO28017.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 KDO28017.1 - 0.058 13.3 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KDO28017.1 - 0.064 13.8 0.0 0.42 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO28017.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KDO28017.1 - 0.086 13.1 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3787 PF12655.7 KDO28017.1 - 0.096 12.6 1.2 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) AAA_33 PF13671.6 KDO28017.1 - 0.097 12.8 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KDO28017.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 KDO28017.1 - 0.11 11.9 0.6 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 KDO28017.1 - 0.17 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO28017.1 - 0.33 11.4 0.5 0.72 10.3 0.5 1.5 1 0 0 1 1 1 0 AAA domain VPS13 PF16908.5 KDO28018.1 - 3.2e-18 66.4 0.0 1.1e-16 61.4 0.0 2.4 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KDO28018.1 - 3.4e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF5546 PF17700.1 KDO28018.1 - 0.099 13.0 0.3 0.44 10.9 0.2 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5546) DUF1765 PF08578.10 KDO28020.1 - 3.2e-22 79.3 0.3 7.7e-22 78.1 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Filo_VP35 PF02097.15 KDO28020.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Filoviridae VP35 DASH_Dad1 PF08649.10 KDO28022.1 - 3.6e-09 36.7 0.0 4.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 HsbA PF12296.8 KDO28022.1 - 0.0018 18.7 0.1 0.0022 18.4 0.1 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DASH_Dam1 PF08653.10 KDO28022.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 KDO28022.1 - 0.029 14.6 0.1 0.034 14.3 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DASH_Dad4 PF08650.10 KDO28022.1 - 0.031 14.2 0.1 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 DASH_Dad2 PF08654.10 KDO28022.1 - 0.051 14.0 0.3 0.06 13.8 0.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 TipAS PF07739.13 KDO28022.1 - 0.12 12.9 0.4 0.13 12.8 0.4 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain dCMP_cyt_deam_1 PF00383.23 KDO28023.1 - 1.7e-21 76.0 0.1 2.4e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KDO28023.1 - 5.4e-18 65.1 0.0 7e-18 64.7 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KDO28023.1 - 0.0015 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 KDO28023.1 - 0.0075 16.4 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KDO28023.1 - 0.0078 16.3 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 KDO28023.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KDO28023.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC4_like PF18774.1 KDO28023.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase zf-C2H2_2 PF12756.7 KDO28024.1 - 0.85 10.0 5.8 0.14 12.5 1.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_10 PF16588.5 KDO28025.1 - 2.9e-05 23.7 7.2 0.0031 17.2 0.3 3.5 4 0 0 4 4 4 2 C2H2 zinc-finger zf-CCHC_4 PF14392.6 KDO28025.1 - 0.026 14.3 11.4 0.098 12.4 0.6 3.4 3 0 0 3 3 3 0 Zinc knuckle Zn_ribbon_17 PF17120.5 KDO28025.1 - 1.3 8.7 7.0 29 4.4 0.1 3.3 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Fer4_8 PF13183.6 KDO28025.1 - 1.5 9.4 7.9 0.55 10.7 1.4 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain FtsJ PF01728.19 KDO28026.1 - 2.1e-66 223.4 0.1 2.5e-66 223.2 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KDO28026.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F B-block_TFIIIC PF04182.12 KDO28027.1 - 0.00098 19.2 0.2 0.015 15.4 0.2 2.8 2 1 0 2 2 2 1 B-block binding subunit of TFIIIC DUF4419 PF14388.6 KDO28028.1 - 3.6e-68 230.2 0.0 4.3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) RRM_1 PF00076.22 KDO28029.1 - 0.0014 18.4 0.0 0.3 10.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.20 KDO28030.1 - 1.6e-18 67.3 0.0 1.2e-15 57.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO28030.1 - 5e-15 56.7 0.3 8.4e-15 56.0 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO28030.1 - 4.7e-05 22.8 0.0 0.00027 20.3 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 UPF0565 PF10561.9 KDO28030.1 - 0.00021 20.6 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Pkinase PF00069.25 KDO28031.1 - 2.1e-68 230.5 0.0 2.6e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28031.1 - 8.6e-28 97.3 0.0 1.1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO28031.1 - 3.4e-10 39.7 0.0 2e-08 33.9 0.0 3.0 3 1 1 4 4 4 1 Kinase-like Kdo PF06293.14 KDO28031.1 - 8.5e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO28031.1 - 5.1e-05 22.2 0.0 7.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO28031.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KDO28031.1 - 0.027 14.1 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KDO28031.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PX PF00787.24 KDO28032.1 - 2e-06 27.7 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 PX domain PRIMA1 PF16101.5 KDO28032.1 - 0.087 12.9 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 fn3 PF00041.21 KDO28034.1 - 1.3e-10 41.4 0.0 5.9e-05 23.3 0.0 2.7 2 1 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO28034.1 - 0.0045 17.5 0.1 1.6 9.3 0.0 2.7 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KDO28034.1 - 0.023 14.6 0.0 0.07 13.1 0.1 1.8 2 1 0 2 2 2 0 Fibronectin-III type domain Ank_3 PF13606.6 KDO28036.1 - 3.1e-08 33.2 0.0 0.02 15.4 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KDO28036.1 - 3.8e-08 33.8 0.0 8e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO28036.1 - 9.3e-07 29.0 0.1 0.15 12.5 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO28036.1 - 1.1e-05 25.6 0.1 0.00059 20.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28036.1 - 0.00015 22.2 0.0 0.00038 21.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Thymidylat_synt PF00303.19 KDO28037.1 - 1.6e-117 391.4 0.0 2e-117 391.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 KDO28037.1 - 1.7e-35 122.1 0.0 5.4e-35 120.5 0.0 1.8 2 0 0 2 2 2 1 Dihydrofolate reductase DUF5471 PF17565.2 KDO28038.1 - 0.038 14.3 0.7 0.15 12.4 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5471) FmiP_Thoc5 PF09766.9 KDO28038.1 - 0.58 9.4 9.0 0.88 8.8 8.8 1.4 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 BRE1 PF08647.11 KDO28038.1 - 2.1 8.5 12.5 0.098 12.7 0.5 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 KDO28038.1 - 3.1 7.1 12.7 7.8 5.7 12.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KDO28038.1 - 5.7 5.7 19.0 27 3.5 16.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Sulfotransfer_1 PF00685.27 KDO28039.1 - 1.3e-11 44.5 2.3 3.2e-10 39.9 2.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KDO28039.1 - 3.6e-09 37.3 1.0 1.6e-06 28.7 1.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family AA_permease PF00324.21 KDO28040.1 - 6.6e-68 229.4 27.4 8.3e-68 229.1 27.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KDO28040.1 - 1.3e-16 60.7 1.9 1.8e-06 27.3 0.0 3.1 2 1 1 3 3 3 3 Solute carrier family 12 PX PF00787.24 KDO28042.1 - 8.5e-06 25.7 0.0 8.5e-06 25.7 0.0 2.4 3 0 0 3 3 3 1 PX domain ARL2_Bind_BART PF11527.8 KDO28043.1 - 6.5e-30 103.6 0.9 6.5e-30 103.6 0.9 2.7 2 1 0 2 2 2 1 The ARF-like 2 binding protein BART TerY_C PF15616.6 KDO28043.1 - 0.06 13.5 0.1 0.99 9.5 0.0 2.5 2 0 0 2 2 2 0 TerY-C metal binding domain Ribosomal_L16 PF00252.18 KDO28044.1 - 3.5e-38 130.6 0.0 4.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Trypsin_2 PF13365.6 KDO28045.1 - 6e-14 53.2 0.0 1.2e-12 48.9 0.0 2.6 2 1 0 2 2 2 1 Trypsin-like peptidase domain FYVE PF01363.21 KDO28045.1 - 7.1e-14 51.7 15.9 1.3e-13 50.9 15.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger SAM_1 PF00536.30 KDO28045.1 - 7.2e-08 32.8 0.0 1.9e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO28045.1 - 0.00013 22.0 0.0 0.00045 20.3 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Trypsin PF00089.26 KDO28045.1 - 0.00021 21.1 0.0 0.0024 17.7 0.0 2.2 1 1 0 1 1 1 1 Trypsin F-box-like PF12937.7 KDO28045.1 - 0.0016 18.3 1.3 0.0035 17.2 1.3 1.6 1 0 0 1 1 1 1 F-box-like FYVE_2 PF02318.16 KDO28045.1 - 0.026 14.7 8.0 0.057 13.6 8.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CRD PF17979.1 KDO28045.1 - 5.7 7.0 10.5 15 5.7 10.5 1.6 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-RING_2 PF13639.6 KDO28045.1 - 6.2 7.2 11.7 13 6.2 11.7 1.6 1 0 0 1 1 1 0 Ring finger domain YuzL PF14115.6 KDO28047.1 - 0.079 13.5 6.3 0.16 12.4 6.3 1.5 1 0 0 1 1 1 0 YuzL-like protein Med17 PF10156.9 KDO28048.1 - 0.045 12.5 0.1 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Subunit 17 of Mediator complex Glucan_synthase PF02364.15 KDO28050.1 - 3e-157 525.2 19.7 2.6e-140 469.2 7.1 4.3 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO28050.1 - 2e-31 109.0 0.2 7.3e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 KDO28050.1 - 1.2e-13 50.7 23.0 1.2e-13 50.7 23.0 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Peptidase_U32 PF01136.19 KDO28051.1 - 0.079 12.1 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 STIMATE PF12400.8 KDO28052.1 - 2.9e-34 118.3 2.8 4.4e-34 117.7 2.8 1.3 1 0 0 1 1 1 1 STIMATE family adh_short_C2 PF13561.6 KDO28053.1 - 2.9e-63 213.6 0.0 3.4e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO28053.1 - 1.7e-14 53.8 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 KDO28053.1 - 0.0017 17.7 0.1 0.0033 16.8 0.0 1.5 2 0 0 2 2 2 1 Trans-2-enoyl-CoA reductase catalytic region Polysacc_synt_2 PF02719.15 KDO28053.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2OG-FeII_Oxy_3 PF13640.6 KDO28054.1 - 7.9e-07 29.9 0.1 1.3e-06 29.1 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SF3b1 PF08920.10 KDO28055.1 - 5.6e-39 133.3 5.6 5.6e-39 133.3 5.6 4.2 1 1 3 4 4 4 1 Splicing factor 3B subunit 1 HEAT PF02985.22 KDO28055.1 - 1.6e-09 37.2 7.7 4.7 7.7 0.0 9.9 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 KDO28055.1 - 5e-07 30.0 6.1 0.058 13.8 0.0 6.6 7 2 2 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 KDO28055.1 - 1.2e-06 28.9 5.7 0.35 11.4 0.0 7.1 7 1 1 8 8 8 1 HEAT-like repeat Cnd1 PF12717.7 KDO28055.1 - 8.6e-06 25.9 5.5 2.7 8.0 0.0 6.0 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KDO28055.1 - 0.00018 20.2 0.9 0.037 12.6 0.1 2.9 2 1 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KDO28055.1 - 0.0002 21.9 0.5 1.8 9.2 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KDO28055.1 - 0.021 14.4 0.2 0.85 9.1 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal NUC173 PF08161.12 KDO28055.1 - 0.039 13.6 0.1 2.5 7.7 0.0 3.5 3 1 0 3 3 3 0 NUC173 domain PVL_ORF50 PF07768.11 KDO28055.1 - 0.31 11.4 4.9 0.94 9.8 4.9 1.8 1 0 0 1 1 1 0 PVL ORF-50-like family DNA_pol_phi PF04931.13 KDO28055.1 - 3 5.8 6.8 8.5 4.3 0.0 3.0 3 0 0 3 3 3 0 DNA polymerase phi Myosin_head PF00063.21 KDO28056.1 - 1.5e-212 707.5 0.3 2.2e-212 707.0 0.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) CBS PF00571.28 KDO28056.1 - 3e-122 399.1 64.1 3.4e-07 30.6 0.1 21.1 21 0 0 21 21 21 19 CBS domain PB1 PF00564.24 KDO28056.1 - 9.1e-11 41.6 0.3 2.4e-10 40.2 0.3 1.8 1 0 0 1 1 1 1 PB1 domain IQ PF00612.27 KDO28056.1 - 2e-05 24.0 12.3 0.0071 16.0 0.4 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF4388 PF14332.6 KDO28056.1 - 0.00033 20.9 0.0 0.52 10.6 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4388) HlyD_2 PF12700.7 KDO28056.1 - 0.0027 16.5 1.1 0.18 10.5 0.2 2.7 1 1 2 3 3 3 1 HlyD family secretion protein AAA_16 PF13191.6 KDO28056.1 - 0.059 13.8 1.4 0.48 10.8 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KDO28056.1 - 0.061 13.6 0.1 2.3 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain bZIP_1 PF00170.21 KDO28056.1 - 0.064 13.4 0.0 0.31 11.2 0.0 2.3 1 0 0 1 1 1 0 bZIP transcription factor DUF1192 PF06698.11 KDO28056.1 - 3.2 7.9 19.5 0.12 12.5 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) ATP-synt_C PF00137.21 KDO28057.1 - 7e-36 122.4 34.4 4.2e-23 81.5 16.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PriCT_1 PF08708.11 KDO28058.1 - 0.12 12.1 1.2 3.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) AAA_6 PF12774.7 KDO28059.1 - 3.1e-136 453.6 0.0 1.7e-132 441.3 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO28059.1 - 6.1e-90 302.2 0.0 6.1e-90 302.2 0.0 3.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 KDO28059.1 - 5.2e-78 262.5 13.3 9.6e-78 261.6 13.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 KDO28059.1 - 5.2e-77 259.1 0.0 1e-76 258.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KDO28059.1 - 9.1e-75 251.3 0.5 1e-73 247.9 0.5 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KDO28059.1 - 2.2e-60 203.3 0.4 4e-55 186.1 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KDO28059.1 - 7.4e-49 165.7 0.2 1.3e-47 161.7 0.0 2.6 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 KDO28059.1 - 5.8e-39 133.5 11.5 1.7e-35 122.2 0.0 3.8 2 1 1 3 3 2 2 ATP-binding dynein motor region Dynein_heavy PF03028.15 KDO28059.1 - 5.2e-32 110.4 0.0 3e-31 108.0 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Kelch_5 PF13854.6 KDO28059.1 - 7.6e-32 108.8 1.0 2.1e-06 27.6 0.0 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KDO28059.1 - 5.8e-31 106.3 3.4 2.2e-07 30.7 0.1 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KDO28059.1 - 6.7e-28 96.4 5.3 2.7e-09 37.1 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO28059.1 - 3.9e-26 90.4 1.7 1.4e-07 31.0 0.0 6.3 6 0 0 6 6 5 3 Kelch motif Kelch_6 PF13964.6 KDO28059.1 - 6.4e-26 89.7 6.5 6.7e-06 26.2 0.1 6.4 4 1 2 6 6 6 4 Kelch motif AAA_lid_1 PF17857.1 KDO28059.1 - 3.1e-23 81.9 0.3 1.9e-22 79.3 0.2 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO28059.1 - 1.9e-19 70.0 0.0 7.3e-08 32.5 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Kelch_2 PF07646.15 KDO28059.1 - 2.3e-19 68.5 10.1 3.3e-06 26.9 0.0 6.6 6 0 0 6 6 6 3 Kelch motif Dynein_AAA_lid PF17852.1 KDO28059.1 - 1.6e-12 47.6 1.2 6.4e-12 45.7 1.2 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Filamin PF00630.19 KDO28059.1 - 5.2e-12 46.5 0.0 6e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 Filamin/ABP280 repeat AAA_16 PF13191.6 KDO28059.1 - 5.3e-09 36.7 0.0 1.2 9.5 0.0 5.3 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 KDO28059.1 - 6.6e-09 36.3 0.2 1.1 9.7 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO28059.1 - 1.9e-06 28.2 0.0 2 8.7 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KDO28059.1 - 5.8e-05 23.6 6.1 2.7 8.5 0.0 5.6 6 0 0 6 6 4 1 AAA domain AAA_19 PF13245.6 KDO28059.1 - 0.00029 21.2 0.1 0.78 10.1 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 KDO28059.1 - 0.0016 18.6 2.5 1.3 9.2 0.0 4.7 5 0 0 5 5 5 1 AAA domain AAA_30 PF13604.6 KDO28059.1 - 0.0017 18.1 0.1 8.8 6.0 0.0 4.3 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 KDO28059.1 - 0.002 18.1 0.1 11 5.9 0.0 4.0 4 0 0 4 4 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 KDO28059.1 - 0.0028 18.0 0.7 15 6.0 0.0 4.2 4 0 0 4 4 3 0 RNA helicase Sigma54_activat PF00158.26 KDO28059.1 - 0.027 14.2 0.0 1.9 8.2 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain TIG PF01833.24 KDO28059.1 - 0.047 13.8 0.7 0.15 12.1 0.7 1.9 1 0 0 1 1 1 0 IPT/TIG domain T2SSE PF00437.20 KDO28059.1 - 0.071 12.2 1.4 0.63 9.0 0.0 2.9 4 0 0 4 4 3 0 Type II/IV secretion system protein DUF4164 PF13747.6 KDO28059.1 - 7.8 6.9 15.4 0.2 12.0 7.5 2.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) Peptidase_C1 PF00112.23 KDO28060.1 - 5.8e-38 131.2 0.2 4e-37 128.4 0.2 2.0 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO28060.1 - 0.012 14.5 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase C1-like family Tir_receptor_N PF07490.11 KDO28060.1 - 0.054 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Peptidase_C1 PF00112.23 KDO28061.1 - 1.3e-38 133.3 1.3 3.1e-37 128.8 0.6 3.0 2 1 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO28061.1 - 0.022 13.5 0.9 2.7 6.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family GlcNAc PF11397.8 KDO28062.1 - 1.7e-46 159.3 6.6 2e-41 142.6 2.2 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Peptidase_C1 PF00112.23 KDO28063.1 - 1.6e-34 119.9 0.0 1.6e-33 116.7 0.0 2.4 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO28063.1 - 0.0078 15.0 0.2 0.039 12.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO28064.1 - 1.2e-37 130.1 0.0 7e-37 127.6 0.0 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO28064.1 - 0.016 14.0 0.3 2.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family cNMP_binding PF00027.29 KDO28065.1 - 9e-19 67.3 0.0 2.1e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO28065.1 - 1.6e-05 24.3 7.6 3.1e-05 23.3 7.7 1.5 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO28066.1 - 2.4e-17 62.7 0.0 8.3e-17 61.0 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO28066.1 - 7e-07 28.7 11.0 1.1e-06 28.1 11.0 1.3 1 0 0 1 1 1 1 Ion transport protein YtzH PF14165.6 KDO28066.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 YtzH-like protein HA PF03457.14 KDO28067.1 - 1.6e-46 156.5 0.0 5.7e-10 39.4 0.0 5.1 5 0 0 5 5 5 4 Helicase associated domain XTBD PF11952.8 KDO28067.1 - 0.082 12.7 0.2 1.3 8.8 0.0 2.9 4 0 0 4 4 4 0 XRN-Two Binding Domain, XTBD Peptidase_C1 PF00112.23 KDO28068.1 - 1.3e-41 143.1 1.7 1.1e-40 140.1 1.7 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO28068.1 - 0.0035 16.2 0.2 0.071 11.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase C1-like family MccV PF17508.2 KDO28068.1 - 0.15 12.6 3.9 0.29 11.7 0.3 2.6 2 0 0 2 2 2 0 Microcin V bacteriocin Castor_Poll_mid PF06241.12 KDO28069.1 - 1.3e-29 102.2 0.0 5e-25 87.5 0.0 2.7 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel DUF3488 PF11992.8 KDO28069.1 - 0.3 10.0 2.6 0.66 8.9 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) UPF0121 PF03661.13 KDO28070.1 - 3.7e-41 141.1 4.7 6e-41 140.4 4.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 KDO28070.1 - 5.7e-15 54.1 5.0 6e-06 26.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO28070.1 - 8.5e-15 53.9 3.2 1.9e-06 27.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO28070.1 - 4.2e-09 36.0 7.4 8.9e-05 22.1 0.2 4.1 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KDO28070.1 - 6.5e-09 36.3 2.6 0.00014 22.4 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO28070.1 - 4.6e-08 32.7 4.5 0.067 13.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO28070.1 - 5.8e-07 29.4 1.2 0.63 10.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO28070.1 - 2.1e-05 25.0 2.2 0.089 13.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28070.1 - 0.00016 22.2 3.9 0.18 12.7 0.1 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO28070.1 - 0.00026 20.7 2.2 0.24 11.3 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO28070.1 - 0.0023 18.2 2.5 0.037 14.3 0.4 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28070.1 - 0.012 15.6 0.9 0.14 12.2 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO28070.1 - 0.28 11.9 1.9 11 6.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BC10 PF06726.12 KDO28071.1 - 0.071 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 ABC_tran_CTD PF16326.5 KDO28074.1 - 0.042 14.1 3.3 0.051 13.8 2.3 1.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain Rep_fac-A_C PF08646.10 KDO28074.1 - 0.35 10.6 4.1 1 9.1 4.1 1.7 1 1 0 1 1 1 0 Replication factor-A C terminal domain DDHD PF02862.17 KDO28075.1 - 1e-22 81.4 0.4 3.7e-18 66.5 0.0 2.3 1 1 1 2 2 2 2 DDHD domain WWE PF02825.20 KDO28075.1 - 0.0013 19.2 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 WWE domain DUF676 PF05057.14 KDO28075.1 - 0.0065 16.0 0.1 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KDO28075.1 - 0.013 16.1 0.1 0.024 15.2 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KDO28075.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DDHD PF02862.17 KDO28076.1 - 2.8e-38 132.3 0.1 1.2e-36 127.0 0.1 2.2 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.14 KDO28076.1 - 0.0032 17.0 0.5 0.036 13.6 0.5 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KDO28076.1 - 0.078 12.2 0.2 0.91 8.7 0.0 2.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KDO28076.1 - 0.1 12.3 0.0 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein GBP PF02263.19 KDO28077.1 - 7.9e-69 231.8 0.0 1.6e-68 230.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KDO28077.1 - 2.2e-15 56.8 1.2 2.2e-15 56.8 1.2 3.0 1 1 2 3 3 3 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 KDO28077.1 - 0.0038 17.3 0.0 0.018 15.1 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase UPF0565 PF10561.9 KDO28078.1 - 4.8e-44 150.8 0.0 3.6e-21 75.7 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 PhzC-PhzF PF02567.16 KDO28081.1 - 1e-43 149.8 0.3 1.3e-43 149.5 0.3 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Gln-synt_N_2 PF16952.5 KDO28081.1 - 0.00096 19.0 0.0 0.096 12.5 0.0 2.4 1 1 1 2 2 2 2 Glutamine synthetase N-terminal domain TruB_N PF01509.18 KDO28082.1 - 0.0072 16.7 1.7 0.015 15.6 1.5 1.5 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TFIIA PF03153.13 KDO28082.1 - 0.3 11.0 11.3 0.32 10.9 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 KDO28082.1 - 7.4 5.0 7.3 10 4.5 7.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FA_hydroxylase PF04116.13 KDO28083.1 - 7.4e-24 84.6 11.9 7.4e-24 84.6 11.9 1.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Gln-synt_C PF00120.24 KDO28084.1 - 1.3e-10 40.9 0.0 5.7e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KDO28084.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 KDO28085.1 - 1.2e-18 67.3 0.0 3.7e-17 62.4 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KDO28085.1 - 9.3e-13 47.7 0.0 1.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF2070 PF09843.9 KDO28086.1 - 1.6 7.0 14.1 2 6.6 14.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1294 PF06961.13 KDO28086.1 - 7.1 7.0 5.4 1.2 9.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) Pkinase PF00069.25 KDO28088.1 - 8.3e-26 90.9 0.0 3.8e-25 88.8 0.0 1.8 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28088.1 - 5.9e-20 71.6 0.0 1.1e-19 70.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO28088.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KDO28090.1 - 3.6e-54 183.8 0.0 4.2e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28090.1 - 6.1e-49 166.7 0.0 7.8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PNP_UDP_1 PF01048.20 KDO28090.1 - 0.0047 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily APH PF01636.23 KDO28090.1 - 0.038 13.9 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO28090.1 - 0.2 10.5 0.0 0.4 9.6 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Ead_Ea22 PF13935.6 KDO28092.1 - 0.048 14.3 0.7 0.053 14.2 0.7 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein PPR_2 PF13041.6 KDO28095.1 - 5.4e-15 55.3 0.7 0.039 14.1 0.0 8.3 6 3 4 10 10 10 4 PPR repeat family PPR PF01535.20 KDO28095.1 - 1.2e-10 40.9 6.2 0.89 9.9 0.0 9.3 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 KDO28095.1 - 1.1e-06 28.2 6.3 0.013 14.8 0.1 4.7 3 1 3 6 6 6 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KDO28095.1 - 3.3e-06 27.1 0.8 13 6.0 0.0 7.0 5 3 4 9 9 9 1 Pentatricopeptide repeat domain BTAD PF03704.17 KDO28095.1 - 0.00049 20.5 4.4 0.85 10.1 0.2 4.7 5 0 0 5 5 5 1 Bacterial transcriptional activator domain TPR_14 PF13428.6 KDO28095.1 - 0.0019 18.9 6.4 0.98 10.4 0.1 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28095.1 - 0.16 12.2 4.4 5.8 7.3 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO28095.1 - 0.56 9.9 1.8 5.6 6.7 0.6 3.0 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 KDO28095.1 - 1 10.2 4.5 61 4.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO28095.1 - 3.3 7.7 6.7 5.5 7.0 0.4 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat mRNA_triPase PF02940.15 KDO28096.1 - 4.6e-24 85.4 0.0 1.7e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 KDO28096.1 - 2.2e-15 57.0 0.0 1.8e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KDO28096.1 - 4.1e-06 27.4 0.0 1e-05 26.1 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain FANCF PF11107.8 KDO28096.1 - 0.096 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) bZIP_1 PF00170.21 KDO28097.1 - 7.8e-12 45.1 15.0 7.8e-12 45.1 15.0 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KDO28097.1 - 2.4e-08 33.9 12.7 2.4e-08 33.9 12.7 2.7 3 0 0 3 3 3 1 Basic region leucine zipper Pox_L3_FP4 PF03339.14 KDO28097.1 - 0.42 9.6 3.5 0.69 8.9 3.5 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein NYD-SP28_assoc PF14775.6 KDO28097.1 - 1 9.5 4.1 0.67 10.1 0.2 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 KDO28097.1 - 2 9.1 12.0 5 7.8 4.1 2.8 2 1 0 3 3 3 0 Initiation control protein YabA bZIP_Maf PF03131.17 KDO28097.1 - 8.8 6.9 15.5 0.67 10.5 8.0 2.6 2 1 0 2 2 2 0 bZIP Maf transcription factor AAA PF00004.29 KDO28098.1 - 5.3e-44 149.9 0.0 1.3e-43 148.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KDO28098.1 - 5.5e-10 39.1 0.1 3.7e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KDO28098.1 - 1.2e-08 35.1 0.1 4.2e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO28098.1 - 2.5e-08 34.2 0.0 6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 KDO28098.1 - 3.1e-06 26.9 0.0 7.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KDO28098.1 - 1.2e-05 25.7 0.2 0.0016 18.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KDO28098.1 - 3.9e-05 22.9 0.0 7.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KDO28098.1 - 0.00016 21.5 0.0 0.00044 20.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KDO28098.1 - 0.00023 21.1 0.1 0.01 15.8 0.0 2.9 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 KDO28098.1 - 0.00054 20.2 2.3 0.019 15.2 0.6 2.9 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KDO28098.1 - 0.00057 19.3 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KDO28098.1 - 0.00066 20.2 0.0 0.0027 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO28098.1 - 0.00084 19.5 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KDO28098.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KDO28098.1 - 0.0012 19.2 0.0 0.0056 17.1 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KDO28098.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KDO28098.1 - 0.0021 18.1 0.0 0.028 14.4 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KDO28098.1 - 0.0031 17.2 0.0 0.0094 15.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KDO28098.1 - 0.0055 16.6 0.1 0.042 13.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO28098.1 - 0.0064 16.2 0.2 0.014 15.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KDO28098.1 - 0.0069 15.9 0.1 0.045 13.3 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KDO28098.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KDO28098.1 - 0.017 14.8 0.2 0.18 11.5 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KDO28098.1 - 0.02 14.6 0.2 0.047 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KDO28098.1 - 0.022 14.8 0.0 0.081 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KDO28098.1 - 0.023 14.6 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF3450 PF11932.8 KDO28098.1 - 0.031 13.6 0.4 0.058 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TniB PF05621.11 KDO28098.1 - 0.071 12.5 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AFG1_ATPase PF03969.16 KDO28098.1 - 0.082 11.8 0.1 0.2 10.5 0.1 1.6 1 1 0 1 1 1 0 AFG1-like ATPase ATPase_2 PF01637.18 KDO28098.1 - 0.083 12.8 0.8 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KDO28098.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 KDO28098.1 - 0.095 12.1 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KDO28098.1 - 0.11 12.0 2.8 0.5 9.9 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO28098.1 - 0.13 12.8 0.2 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain CAP_C PF08603.11 KDO28099.1 - 2e-13 50.2 0.6 2.8e-13 49.8 0.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KDO28099.1 - 3.5e-07 30.0 1.9 5.2e-07 29.4 1.9 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C Glucan_synthase PF02364.15 KDO28100.1 - 3.6e-197 657.3 16.2 5.1e-174 580.7 12.8 3.2 1 1 1 2 2 2 2 1,3-beta-glucan synthase component SKN1 PF03935.15 KDO28100.1 - 2.2e-77 260.6 2.8 3.6e-77 259.9 2.8 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FKS1_dom1 PF14288.6 KDO28100.1 - 1.2e-20 74.1 1.9 2.2e-19 70.1 1.9 2.3 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_16 PF00722.21 KDO28100.1 - 2.4e-06 27.1 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 RasGAP PF00616.19 KDO28101.1 - 2.6e-24 86.1 0.1 3.9e-18 65.9 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KDO28101.1 - 5.9e-12 46.0 0.0 1.2e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO28101.1 - 0.065 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain USP8_interact PF08941.10 KDO28101.1 - 0.14 12.0 0.7 0.26 11.1 0.4 1.6 1 1 0 1 1 1 0 USP8 interacting PEP-utilisers_N PF05524.13 KDO28101.1 - 2 8.6 5.6 2.5 8.3 0.0 3.0 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Not1 PF04054.15 KDO28102.1 - 6.6e-135 449.7 0.6 6.6e-135 449.7 0.6 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KDO28102.1 - 1.3e-84 283.1 0.1 4.3e-83 278.1 0.0 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KDO28102.1 - 2.8e-55 186.3 3.0 8.4e-55 184.7 1.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KDO28102.1 - 6e-54 182.1 0.4 1.5e-53 180.8 0.1 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KDO28102.1 - 3.3e-16 59.7 0.0 9.2e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Pkinase_Tyr PF07714.17 KDO28103.1 - 3.5e-19 69.1 0.0 4.1e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28103.1 - 1.8e-10 40.7 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28105.1 - 4.1e-38 131.1 0.0 4.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28105.1 - 1.5e-32 113.0 0.0 1.9e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28106.1 - 8.5e-34 117.0 0.0 1.1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28106.1 - 5.8e-26 91.4 0.0 7.3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO28106.1 - 0.13 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like zf-SCNM1 PF15803.5 KDO28106.1 - 0.19 11.4 1.7 33 4.2 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 Pkinase PF00069.25 KDO28107.1 - 2.8e-36 125.2 0.0 3.6e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28107.1 - 3.5e-33 115.0 0.0 5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KDO28108.1 - 8e-41 140.0 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28108.1 - 8e-38 130.3 0.0 1e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO28108.1 - 0.0022 17.4 0.1 0.0037 16.6 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TB2_DP1_HVA22 PF03134.19 KDO28109.1 - 2.1e-14 53.2 2.9 2.1e-14 53.2 2.9 1.7 2 1 0 2 2 2 1 TB2/DP1, HVA22 family COPI_assoc PF08507.10 KDO28111.1 - 9.5e-09 35.4 3.6 1.1e-08 35.2 3.6 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2561 PF10812.8 KDO28111.1 - 0.036 14.1 0.6 5.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Nup54 PF13874.6 KDO28112.1 - 0.14 12.3 4.0 0.27 11.3 3.8 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Aminotran_1_2 PF00155.21 KDO28113.1 - 6.7e-61 206.5 0.0 7.7e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KDO28113.1 - 4.4e-07 28.8 0.0 1.1e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KDO28113.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KDO28113.1 - 0.0028 16.7 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KDO28113.1 - 0.16 11.3 0.3 0.25 10.6 0.3 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2985 PF11204.8 KDO28114.1 - 3.8e-08 33.4 2.3 3.8e-08 33.4 2.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) HTH_30 PF13556.6 KDO28114.1 - 0.011 15.5 0.9 0.017 14.9 0.1 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain LapA_dom PF06305.11 KDO28114.1 - 0.67 9.8 3.6 7.6 6.4 1.2 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 KDO28114.1 - 0.97 8.1 2.1 1.6 7.4 2.1 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Mg_trans_NIPA PF05653.14 KDO28115.1 - 3.3e-32 111.8 8.2 4.9e-32 111.2 8.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KDO28115.1 - 4e-05 23.8 1.0 4e-05 23.8 1.0 4.0 3 1 2 5 5 5 1 EamA-like transporter family UAA PF08449.11 KDO28115.1 - 0.0051 16.0 2.9 0.0097 15.1 0.1 2.4 2 1 0 3 3 3 1 UAA transporter family TMEM234 PF10639.9 KDO28115.1 - 0.0069 16.4 0.5 0.019 15.0 0.0 2.1 2 1 0 2 2 2 1 Putative transmembrane family 234 EmrE PF13536.6 KDO28115.1 - 0.03 13.9 0.4 0.03 13.9 0.4 3.2 3 1 1 4 4 4 0 Putative multidrug resistance efflux transporter MgtE PF01769.16 KDO28116.1 - 2.5e-25 89.3 4.4 2.5e-25 89.3 4.4 1.8 2 0 0 2 2 2 1 Divalent cation transporter DUF5345 PF17280.2 KDO28116.1 - 0.024 14.6 0.3 0.024 14.6 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Tmemb_170 PF10190.9 KDO28116.1 - 0.069 13.5 1.3 0.069 13.5 1.3 2.4 2 1 0 2 2 2 0 Putative transmembrane protein 170 DUF4191 PF13829.6 KDO28116.1 - 1.3 8.3 5.1 0.28 10.5 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Thioredoxin PF00085.20 KDO28117.1 - 2.4e-137 448.3 0.0 8.7e-31 106.0 0.0 6.1 6 0 0 6 6 6 6 Thioredoxin Thioredoxin_2 PF13098.6 KDO28117.1 - 6.3e-32 110.3 3.3 1.6e-05 25.3 0.1 8.6 6 4 0 6 6 6 6 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO28117.1 - 6.5e-25 87.1 0.7 0.00013 22.1 0.0 6.5 6 0 0 6 6 6 6 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO28117.1 - 1.9e-22 79.4 6.1 0.085 13.2 0.0 10.8 6 6 5 11 11 11 6 Thioredoxin-like AhpC-TSA PF00578.21 KDO28117.1 - 1.2e-20 73.7 0.2 0.0072 16.2 0.0 6.2 6 0 0 6 6 6 5 AhpC/TSA family HyaE PF07449.11 KDO28117.1 - 6.1e-19 68.0 0.3 0.0028 17.6 0.0 6.4 6 0 0 6 6 6 5 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KDO28117.1 - 3.2e-18 66.4 0.1 0.00038 20.4 0.0 6.4 7 0 0 7 7 6 3 F plasmid transfer operon protein OST3_OST6 PF04756.13 KDO28117.1 - 6.4e-18 65.1 0.0 0.01 15.2 0.0 6.1 5 1 1 6 6 6 4 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KDO28117.1 - 9.3e-15 54.4 0.0 0.44 10.6 0.0 6.2 6 0 0 6 6 6 4 Thioredoxin domain Glutaredoxin PF00462.24 KDO28117.1 - 4.5e-13 49.2 3.2 0.053 13.8 0.0 6.4 6 1 0 6 6 6 3 Glutaredoxin Thioredoxin_9 PF14595.6 KDO28117.1 - 2.5e-11 43.5 0.0 0.087 12.6 0.0 5.3 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.6 KDO28117.1 - 5.3e-11 42.8 0.0 0.023 14.6 0.0 5.7 6 0 0 6 6 6 2 Thioredoxin-like domain Redoxin PF08534.10 KDO28117.1 - 1.3e-10 41.2 2.2 0.044 13.5 0.0 6.5 6 1 1 7 7 7 2 Redoxin DUF836 PF05768.14 KDO28117.1 - 4.2e-08 33.5 0.0 4.9 7.6 0.0 5.4 6 0 0 6 6 5 2 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KDO28117.1 - 2.4e-06 27.5 1.4 0.21 11.4 0.0 5.9 5 2 1 6 6 6 1 DSBA-like thioredoxin domain ERp29_N PF07912.13 KDO28117.1 - 0.003 17.7 0.2 10 6.3 0.0 4.3 5 0 0 5 5 5 0 ERp29, N-terminal domain Calsequestrin PF01216.17 KDO28117.1 - 0.0041 16.2 0.5 5.6 5.9 0.0 3.5 4 0 0 4 4 4 2 Calsequestrin Thioredoxin_4 PF13462.6 KDO28117.1 - 0.0063 16.7 0.7 34 4.5 0.0 5.5 6 1 1 7 7 7 0 Thioredoxin zf_C2H2_ZHX PF18387.1 KDO28117.1 - 0.0095 15.6 0.9 9.5 6.0 0.1 3.6 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain PH PF00169.29 KDO28118.1 - 1.1e-09 38.7 0.0 0.00062 20.2 0.0 3.0 2 1 0 2 2 2 2 PH domain PH_9 PF15410.6 KDO28118.1 - 0.0024 18.2 0.3 0.54 10.6 0.0 3.2 3 1 0 3 3 3 1 Pleckstrin homology domain Pkinase PF00069.25 KDO28119.1 - 9.9e-16 57.9 0.0 2.9e-15 56.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28119.1 - 0.0028 17.0 0.0 0.0074 15.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase GST_C_3 PF14497.6 KDO28120.1 - 7.6e-10 38.9 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO28120.1 - 1.3e-08 35.1 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO28120.1 - 0.0004 20.7 0.0 0.0009 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO28120.1 - 0.00041 20.3 1.0 0.00098 19.1 1.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO28120.1 - 0.0021 18.2 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO28121.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO28121.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO28121.1 - 0.0024 18.2 0.0 0.0074 16.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO28121.1 - 0.088 12.8 0.4 0.19 11.8 0.4 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO28122.1 - 2e-06 28.0 0.0 2.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO28122.1 - 0.044 14.2 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO28123.1 - 2e-14 53.6 0.0 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO28123.1 - 7.5e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO28123.1 - 4.8e-05 23.3 0.2 0.00027 20.9 0.2 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KDO28123.1 - 0.0048 17.5 0.0 0.0083 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO28123.1 - 0.05 14.0 0.0 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO28123.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PX PF00787.24 KDO28124.1 - 3.3e-06 27.1 0.0 5.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PX domain Gp-FAR-1 PF05823.12 KDO28125.1 - 0.035 14.5 0.1 0.092 13.1 0.1 1.7 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CPP1-like PF11833.8 KDO28126.1 - 0.036 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3522 PF12036.8 KDO28126.1 - 3.1 8.0 6.7 0.45 10.8 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) RAP80_UIM PF18282.1 KDO28129.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif HA PF03457.14 KDO28130.1 - 8.3e-42 141.4 3.6 1.4e-10 41.3 0.1 5.3 5 0 0 5 5 5 5 Helicase associated domain Sdh5 PF03937.16 KDO28133.1 - 0.046 13.7 0.1 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase zf-CCCH_4 PF18044.1 KDO28134.1 - 1.7e-13 50.0 13.6 6.5e-07 29.0 3.5 3.1 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO28134.1 - 1e-10 41.3 19.1 1.8e-05 24.6 5.9 2.9 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KDO28134.1 - 1e-09 38.0 10.0 0.00022 21.1 1.4 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHY PF05495.12 KDO28134.1 - 1.2e-06 28.9 14.3 1.2e-06 28.9 14.3 4.8 3 2 3 6 6 6 1 CHY zinc finger Torus PF16131.5 KDO28134.1 - 0.00048 20.8 9.1 0.0043 17.7 0.8 3.0 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 KDO28134.1 - 0.0012 19.2 13.8 0.25 11.9 1.8 3.1 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Myb_DNA-binding PF00249.31 KDO28134.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-CCCH_3 PF15663.5 KDO28134.1 - 5.8 7.2 17.1 0.071 13.3 6.1 3.0 2 2 1 3 3 3 0 Zinc-finger containing family UPRTase PF14681.6 KDO28135.1 - 2.7e-26 92.3 0.0 6.1e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase HA PF03457.14 KDO28136.1 - 8.3e-44 147.8 1.8 2e-14 53.7 0.0 5.2 5 0 0 5 5 5 5 Helicase associated domain Ank_2 PF12796.7 KDO28137.1 - 2.9e-29 101.5 2.8 1.8e-12 47.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28137.1 - 8.6e-28 96.4 2.2 2.2e-08 34.5 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28137.1 - 1.3e-27 92.8 2.4 0.00011 22.3 0.1 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KDO28137.1 - 1.7e-24 85.1 10.4 5.2e-06 26.7 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KDO28137.1 - 3.5e-21 75.0 13.8 4.6e-07 30.0 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) HMG-CoA_red PF00368.18 KDO28140.1 - 2.7e-80 270.1 5.9 5.4e-80 269.2 5.9 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DDE_Tnp_1_3 PF13612.6 KDO28140.1 - 0.21 11.6 0.0 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 Transposase DDE domain ACPS PF01648.20 KDO28141.1 - 4.5e-14 52.6 0.0 5.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Got1 PF04178.12 KDO28142.1 - 2e-29 102.3 12.0 2e-29 102.3 12.0 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family DUF5337 PF17272.2 KDO28142.1 - 0.28 11.0 3.2 1.4 8.8 3.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5337) CCB1 PF12046.8 KDO28142.1 - 0.38 10.1 3.8 0.61 9.4 3.8 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B TcpE PF12648.7 KDO28142.1 - 2 9.0 7.4 1.3 9.6 4.1 1.9 1 1 1 2 2 2 0 TcpE family MMPL PF03176.15 KDO28142.1 - 4.8 6.0 9.0 0.87 8.5 5.4 1.5 2 0 0 2 2 2 0 MMPL family 2-Hacid_dh_C PF02826.19 KDO28143.1 - 1.1e-37 129.2 0.0 1.8e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KDO28143.1 - 2e-05 24.8 0.3 4.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KDO28143.1 - 0.024 14.6 0.6 2.5 8.0 0.6 2.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KDO28143.1 - 0.038 14.6 0.0 0.093 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KDO28143.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KDO28143.1 - 0.16 12.2 2.4 1.2 9.4 2.4 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain cNMP_binding PF00027.29 KDO28144.1 - 4.8e-37 125.9 0.2 6.1e-14 51.9 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ank_4 PF13637.6 KDO28144.1 - 4.3e-13 49.5 0.1 1.4e-06 28.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28144.1 - 2.5e-10 39.7 1.1 5.5e-05 23.3 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KDO28144.1 - 2.6e-10 40.8 0.6 3.7e-09 37.0 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28144.1 - 2.3e-09 37.3 0.5 8.2e-09 35.6 0.5 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MT PF12777.7 KDO28144.1 - 9.4e-09 34.7 0.7 1.5e-08 34.1 0.7 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Ank PF00023.30 KDO28144.1 - 1.5e-08 34.7 2.5 2.8e-05 24.4 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat SspB PF04386.13 KDO28144.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Stringent starvation protein B Dimer_Tnp_hAT PF05699.14 KDO28146.1 - 0.15 11.9 0.0 3 7.7 0.0 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Cupin_6 PF12852.7 KDO28148.1 - 0.073 12.8 0.2 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Cupin Presenilin PF01080.17 KDO28149.1 - 2.7 6.7 11.7 3.8 6.2 11.7 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KDO28149.1 - 7.7 4.9 12.7 8.9 4.7 12.7 1.0 1 0 0 1 1 1 0 Macoilin family Mito_carr PF00153.27 KDO28150.1 - 6.5e-51 170.2 7.2 6.6e-19 67.6 0.6 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CPL PF08144.11 KDO28151.1 - 0.077 13.4 0.0 0.66 10.3 0.0 2.6 2 0 0 2 2 2 0 CPL (NUC119) domain ECH_1 PF00378.20 KDO28152.1 - 1.9e-43 148.6 0.0 3.3e-43 147.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO28152.1 - 2.5e-27 96.3 0.0 1.6e-21 77.2 0.0 2.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase GATase_3 PF07685.14 KDO28153.1 - 2e-29 102.6 0.0 3.9e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Kelch_5 PF13854.6 KDO28153.1 - 1.9e-26 91.6 6.4 1.5e-05 24.8 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KDO28153.1 - 2.7e-25 87.8 13.3 5.4e-06 26.5 0.1 7.4 4 2 3 7 7 7 4 Kelch motif Kelch_1 PF01344.25 KDO28153.1 - 1.3e-23 82.3 12.6 0.00022 20.7 0.7 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KDO28153.1 - 3e-23 81.6 22.4 3.1e-08 33.7 0.4 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KDO28153.1 - 1.9e-19 69.4 10.3 6.1e-06 26.1 0.4 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain CbiA PF01656.23 KDO28153.1 - 1.4e-16 60.7 0.0 2.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KDO28153.1 - 1.6e-15 57.5 0.0 5.3e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Kelch_2 PF07646.15 KDO28153.1 - 1.6e-15 56.3 9.2 1.9e-05 24.4 0.1 5.9 5 0 0 5 5 5 3 Kelch motif DUF5522 PF17653.1 KDO28153.1 - 1e-13 51.0 4.6 2.8e-13 49.6 4.6 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Peripla_BP_2 PF01497.18 KDO28153.1 - 0.00034 20.2 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein AAA_16 PF13191.6 KDO28153.1 - 0.052 13.9 1.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF2163 PF09931.9 KDO28153.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) Mito_carr PF00153.27 KDO28154.1 - 1.3e-38 130.8 11.2 8e-18 64.2 0.4 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein MBF1 PF08523.10 KDO28155.1 - 4.8e-14 52.6 3.3 9e-14 51.7 3.3 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KDO28155.1 - 1.5e-13 50.6 0.1 2.2e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KDO28155.1 - 1.4e-05 25.3 0.0 3.3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KDO28155.1 - 0.0079 16.2 0.1 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Peptidase_M13_N PF05649.13 KDO28159.1 - 4.5e-65 220.8 0.0 5.7e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO28159.1 - 3.5e-60 203.1 0.0 1e-59 201.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M13 YARHG PF13308.6 KDO28159.1 - 0.039 13.9 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 YARHG domain Methyltransf_16 PF10294.9 KDO28160.1 - 2.8e-20 72.8 0.0 4.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KDO28160.1 - 3.3e-10 40.0 0.0 5.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO28160.1 - 2.9e-09 37.5 0.0 8.5e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO28160.1 - 1.7e-08 34.3 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO28160.1 - 8e-07 28.8 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KDO28160.1 - 2.6e-05 24.1 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO28160.1 - 3.5e-05 24.5 0.0 9.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO28160.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KDO28160.1 - 0.00013 22.5 0.0 0.00035 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KDO28160.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KDO28160.1 - 0.022 14.1 0.0 0.059 12.7 0.0 1.7 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KDO28160.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KDO28160.1 - 0.06 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KDO28160.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Seadorna_VP6 PF07407.11 KDO28161.1 - 0.24 10.3 2.0 0.43 9.5 2.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein Cep57_CLD PF14073.6 KDO28162.1 - 1.3e-06 28.6 50.7 0.0038 17.3 9.1 3.8 1 1 3 4 4 4 2 Centrosome localisation domain of Cep57 Cast PF10174.9 KDO28162.1 - 0.0017 16.7 11.8 0.0017 16.7 11.8 3.1 1 1 2 3 3 3 2 RIM-binding protein of the cytomatrix active zone Csm1_N PF18504.1 KDO28162.1 - 0.82 10.1 37.6 0.41 11.0 1.9 6.6 2 2 6 8 8 8 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 KDO28162.1 - 1.8 7.9 50.6 3.7 6.9 5.7 3.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 BRI3BP PF14965.6 KDO28162.1 - 6.3 6.3 8.7 7.8 6.0 0.6 3.5 3 0 0 3 3 3 0 Negative regulator of p53/TP53 Patatin PF01734.22 KDO28163.1 - 1.1e-23 84.5 0.1 2.1e-23 83.6 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 KDO28163.1 - 3.6e-14 52.6 0.2 5.1e-07 29.7 0.0 3.6 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain O_anti_polymase PF01901.16 KDO28164.1 - 0.026 13.8 1.9 0.15 11.3 0.1 2.1 2 0 0 2 2 2 0 Putative O-antigen polymerase Marek_A PF02124.15 KDO28164.1 - 0.047 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A 2-Hacid_dh_C PF02826.19 KDO28165.1 - 1.4e-37 128.8 0.0 4.5e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO28165.1 - 1.2e-26 93.0 0.0 1.3e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Hexapep PF00132.24 KDO28166.1 - 7.4e-27 92.0 34.1 2.2e-07 30.3 1.2 6.1 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KDO28166.1 - 4.3e-09 36.0 30.2 0.019 14.7 5.4 5.9 4 2 1 6 6 6 5 Hexapeptide repeat of succinyl-transferase RRM_1 PF00076.22 KDO28167.1 - 1.8e-20 72.5 0.1 2.6e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 KDO28167.1 - 2.1e-11 43.7 5.6 3.8e-11 42.9 5.6 1.4 1 0 0 1 1 1 1 WW domain RRM_5 PF13893.6 KDO28167.1 - 7.5e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KDO28167.1 - 0.028 14.6 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 Glyco_hyd_101C PF17451.2 KDO28167.1 - 0.029 14.7 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain HHH_3 PF12836.7 KDO28168.1 - 1.3e-14 54.2 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 KDO28168.1 - 9.7e-11 41.6 0.3 1.5e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PsbU PF06514.11 KDO28168.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH PF00633.23 KDO28168.1 - 0.017 15.0 0.1 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glyco_hydro_3 PF00933.21 KDO28169.1 - 1.2e-53 182.5 0.2 1.8e-53 182.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ricin_B_lectin PF00652.22 KDO28169.1 - 8.3e-30 103.7 7.6 1.9e-14 54.0 2.3 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_3_C PF01915.22 KDO28169.1 - 1.1e-27 97.4 1.7 1.2e-27 97.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain RicinB_lectin_2 PF14200.6 KDO28169.1 - 1.8e-11 44.6 9.2 8.4e-06 26.4 1.2 3.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Fn3-like PF14310.6 KDO28169.1 - 1.2e-09 38.2 0.0 3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CDtoxinA PF03498.14 KDO28169.1 - 5.5e-05 22.8 0.2 0.21 11.2 0.1 2.5 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain PQQ PF01011.21 KDO28169.1 - 0.065 13.2 0.6 15 5.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Glyco_hydro_3 PF00933.21 KDO28170.1 - 2.3e-50 171.8 0.0 3.1e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KDO28170.1 - 2.1e-34 119.3 0.0 4.2e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Ricin_B_lectin PF00652.22 KDO28170.1 - 8.8e-29 100.3 5.2 1e-13 51.6 1.1 2.6 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO28170.1 - 1e-10 42.2 4.2 2.9e-05 24.7 0.1 3.4 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Fn3-like PF14310.6 KDO28170.1 - 2.6e-10 40.2 0.0 8.4e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain CDtoxinA PF03498.14 KDO28170.1 - 0.0055 16.3 0.3 3.5 7.2 0.0 2.7 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain PQQ PF01011.21 KDO28170.1 - 0.012 15.5 0.1 11 6.2 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat DUF11 PF01345.18 KDO28170.1 - 0.14 12.4 2.0 0.89 9.9 2.0 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF11 Glyco_hydro_3 PF00933.21 KDO28171.1 - 9.9e-58 196.0 0.0 1.5e-57 195.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KDO28171.1 - 4.1e-33 115.1 0.0 9e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KDO28171.1 - 8.9e-10 38.5 0.0 2.5e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Ricin_B_lectin PF00652.22 KDO28171.1 - 0.00018 21.8 0.1 0.00033 20.9 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DAO PF01266.24 KDO28172.1 - 1.5e-26 93.8 0.1 1.9e-25 90.2 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KDO28172.1 - 0.00013 21.2 0.3 0.023 13.8 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KDO28172.1 - 0.0006 19.0 0.2 0.013 14.6 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KDO28172.1 - 0.013 14.7 0.0 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO28172.1 - 0.023 13.9 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KDO28172.1 - 0.089 13.0 0.3 0.29 11.4 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KDO28172.1 - 0.1 11.9 0.3 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MMR_HSR1 PF01926.23 KDO28173.1 - 6.3e-53 177.7 0.2 6.1e-26 90.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 KDO28173.1 - 5.4e-32 110.0 0.2 1.2e-31 108.8 0.2 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 KDO28173.1 - 7.4e-30 103.5 0.4 2.7e-17 62.7 0.2 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KDO28173.1 - 1.3e-15 57.5 0.2 3.2e-09 36.6 0.6 4.9 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Ras PF00071.22 KDO28173.1 - 2.7e-14 53.1 0.0 8.1e-09 35.3 0.0 3.1 2 2 0 2 2 2 2 Ras family Dynamin_N PF00350.23 KDO28173.1 - 5.9e-14 52.5 1.5 0.012 15.7 0.0 4.6 3 1 1 4 4 4 3 Dynamin family Arf PF00025.21 KDO28173.1 - 9.1e-11 41.5 0.2 7.5e-07 28.8 0.1 3.1 2 2 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KDO28173.1 - 2.2e-10 40.8 0.1 0.00055 20.1 0.0 3.8 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KDO28173.1 - 2.3e-10 40.2 0.1 8.3e-06 25.3 0.1 2.2 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KDO28173.1 - 2.1e-09 37.5 0.1 0.029 14.3 0.0 3.6 3 1 0 3 3 3 2 RsgA GTPase NB-ARC PF00931.22 KDO28173.1 - 2.7e-08 33.3 0.1 2.1e-05 23.8 0.2 2.2 2 0 0 2 2 2 2 NB-ARC domain SRPRB PF09439.10 KDO28173.1 - 4.9e-07 29.3 0.0 0.0054 16.2 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KDO28173.1 - 7.8e-06 26.5 0.0 0.21 12.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter TniB PF05621.11 KDO28173.1 - 3e-05 23.5 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_18 PF13238.6 KDO28173.1 - 5.4e-05 23.7 0.0 0.45 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KDO28173.1 - 9.4e-05 21.5 0.1 1.5 7.7 0.0 3.6 3 1 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KDO28173.1 - 0.00014 22.1 0.2 1.3 9.3 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO28173.1 - 0.0042 16.8 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KDO28173.1 - 0.005 16.6 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KDO28173.1 - 0.0058 16.6 1.0 0.97 9.3 0.0 2.9 3 0 0 3 3 3 1 NTPase G-alpha PF00503.20 KDO28173.1 - 0.0059 15.8 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit RNA_helicase PF00910.22 KDO28173.1 - 0.0081 16.5 0.0 4.4 7.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Septin PF00735.18 KDO28173.1 - 0.026 13.8 0.1 8.6 5.5 0.0 3.0 2 1 1 3 3 3 0 Septin AAA_16 PF13191.6 KDO28173.1 - 0.032 14.6 0.1 7.6 6.9 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 KDO28173.1 - 0.036 14.0 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SCP_3 PF17844.1 KDO28173.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SCP ortholog MobB PF03205.14 KDO28173.1 - 0.075 12.9 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 KDO28173.1 - 0.09 12.1 0.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 KDO28173.1 - 0.1 12.6 0.1 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO28173.1 - 0.11 12.7 0.0 24 5.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain NAD_binding_5 PF07994.12 KDO28174.1 - 1.5e-144 481.3 0.0 1.8e-144 481.0 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KDO28174.1 - 4.2e-48 162.1 0.2 7.9e-48 161.2 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Vps39_2 PF10367.9 KDO28175.1 - 2.6e-26 92.2 0.5 1.1e-25 90.2 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KDO28175.1 - 1.2e-20 74.2 0.0 2.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 KDO28175.1 - 8.3e-06 26.1 1.6 6.4e-05 23.2 0.0 3.2 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 TPR_16 PF13432.6 KDO28175.1 - 0.0042 17.7 1.2 0.98 10.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 KDO28175.1 - 0.061 13.2 0.0 11 5.8 0.0 3.1 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.17 KDO28175.1 - 0.75 10.1 3.2 15 6.0 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Alpha_kinase PF02816.18 KDO28176.1 - 7.5e-55 185.9 0.0 1.2e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 KDO28176.1 - 0.0036 17.0 0.2 0.007 16.1 0.2 1.5 1 0 0 1 1 1 1 Short C-terminal domain Ion_trans PF00520.31 KDO28177.1 - 5.9e-40 137.0 40.0 8.9e-30 103.7 18.5 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 KDO28177.1 - 0.00024 21.5 0.7 0.00051 20.4 0.7 1.5 1 0 0 1 1 1 1 EF-hand domain pair FAM176 PF14851.6 KDO28177.1 - 0.0034 17.0 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 FAM176 family DUF4834 PF16118.5 KDO28177.1 - 0.077 14.0 0.3 30 5.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EF-hand_6 PF13405.6 KDO28177.1 - 0.097 12.7 0.3 0.31 11.1 0.2 1.9 2 0 0 2 2 2 0 EF-hand domain Ion_trans PF00520.31 KDO28178.1 - 5.5e-40 137.1 42.1 1.2e-28 100.0 19.5 2.1 2 0 0 2 2 2 2 Ion transport protein NUDE_C PF04880.13 KDO28179.1 - 0.036 14.5 0.4 0.045 14.2 0.4 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GST_C_3 PF14497.6 KDO28181.1 - 5.8e-12 45.7 0.1 7.7e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO28181.1 - 1.3e-05 25.3 0.0 2.4e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO28181.1 - 0.00019 21.4 0.1 0.00051 20.0 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO28181.1 - 0.041 14.2 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KDO28181.1 - 0.089 13.4 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO28182.1 - 7e-07 29.4 0.0 3.8e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO28182.1 - 0.0027 17.7 0.1 0.019 14.9 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO28182.1 - 0.0061 16.8 0.0 0.0088 16.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RabGAP-TBC PF00566.18 KDO28184.1 - 2.5e-37 128.6 0.0 9.5e-37 126.7 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SQS_PSY PF00494.19 KDO28185.1 - 4.5e-42 144.4 0.0 6.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Neurensin PF14927.6 KDO28185.1 - 0.064 13.0 2.1 1.2 8.9 0.1 3.1 3 0 0 3 3 3 0 Neurensin MutS_V PF00488.21 KDO28187.1 - 8.7e-29 100.9 0.2 2.4e-27 96.2 0.2 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KDO28187.1 - 6.7e-23 81.9 0.1 1.3e-22 81.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain III ABC_tran PF00005.27 KDO28187.1 - 0.002 18.6 0.0 0.0062 17.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter TehB PF03848.14 KDO28187.1 - 0.016 14.6 0.2 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TehB AAA_30 PF13604.6 KDO28187.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO28187.1 - 0.043 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SOR_SNZ PF01680.17 KDO28187.1 - 0.06 13.1 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 SOR/SNZ family AAA_10 PF12846.7 KDO28187.1 - 0.069 12.1 0.3 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain MutS_IV PF05190.18 KDO28187.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA_22 PF13401.6 KDO28187.1 - 0.11 12.8 1.1 1.3 9.3 0.4 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KDO28187.1 - 0.11 12.2 0.3 0.7 9.6 0.0 2.3 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF5335 PF17269.2 KDO28188.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5335) Elicitin PF00964.17 KDO28189.1 - 5.5e-06 26.4 0.6 1e-05 25.6 0.6 1.4 1 0 0 1 1 1 1 Elicitin PGK PF00162.19 KDO28190.1 - 4e-160 532.9 0.3 4.9e-160 532.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 KDO28190.1 - 0.023 14.3 1.4 2.5 7.6 0.0 3.6 4 1 0 4 4 4 0 Propionate catabolism activator PH PF00169.29 KDO28191.1 - 8.9e-05 23.0 0.2 0.00035 21.1 0.1 2.1 2 1 0 2 2 2 1 PH domain VHS PF00790.19 KDO28191.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 VHS domain zf-RING_2 PF13639.6 KDO28192.1 - 3.4e-10 40.1 13.2 7.8e-10 38.9 13.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO28192.1 - 6e-09 36.1 9.3 1.3e-08 35.0 9.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO28192.1 - 5.4e-06 26.3 8.7 1e-05 25.4 8.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KDO28192.1 - 1.6e-05 24.6 7.8 3.5e-05 23.5 7.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KDO28192.1 - 6.8e-05 22.7 10.0 6.8e-05 22.7 10.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO28192.1 - 0.00013 21.8 13.3 0.00021 21.1 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO28192.1 - 0.00016 21.4 12.9 0.00029 20.6 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO28192.1 - 0.0002 21.3 10.2 0.00033 20.6 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KDO28192.1 - 0.00097 18.7 4.9 0.0017 17.9 4.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO28192.1 - 0.017 15.0 9.0 0.032 14.1 9.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO28192.1 - 0.024 14.7 7.3 0.084 12.9 7.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KDO28192.1 - 0.047 13.9 7.5 0.14 12.3 7.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KDO28192.1 - 0.16 12.2 4.5 0.12 12.6 2.7 1.7 2 0 0 2 2 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 KDO28192.1 - 0.71 10.2 9.7 1.2 9.5 9.7 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KDO28192.1 - 3.1 8.0 11.4 6.2 7.0 11.4 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KDO28192.1 - 9.8 6.1 7.4 23 4.9 7.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AIRS_C PF02769.22 KDO28193.1 - 2.2e-23 83.1 0.1 4.2e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KDO28193.1 - 4.2e-11 43.3 0.1 9.5e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain SAM_PNT PF02198.16 KDO28193.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain cNMP_binding PF00027.29 KDO28194.1 - 4.3e-17 62.0 0.1 6.6e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TPR_9 PF13371.6 KDO28194.1 - 0.0005 20.2 0.4 0.003 17.7 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO28194.1 - 0.0013 19.2 0.2 0.0042 17.6 0.0 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat FAD_syn PF06574.12 KDO28194.1 - 0.0076 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD synthetase TPR_14 PF13428.6 KDO28194.1 - 0.01 16.6 0.0 0.24 12.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat 14-3-3 PF00244.20 KDO28194.1 - 0.023 14.2 0.1 0.064 12.8 0.1 1.7 1 0 0 1 1 1 0 14-3-3 protein TPR_11 PF13414.6 KDO28194.1 - 0.066 12.9 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 KDO28194.1 - 0.15 12.3 4.1 1.8 8.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28194.1 - 0.28 11.4 5.0 0.74 10.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KDO28194.1 - 0.44 10.7 3.1 2.7 8.1 0.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 PA28_beta PF02252.18 KDO28194.1 - 0.45 10.2 2.2 0.89 9.2 0.2 2.4 2 1 1 3 3 3 0 Proteasome activator pa28 beta subunit Tektin PF03148.14 KDO28195.1 - 0.033 12.9 2.6 0.049 12.4 2.6 1.1 1 0 0 1 1 1 0 Tektin family Golgin_A5 PF09787.9 KDO28195.1 - 0.05 13.1 2.0 0.073 12.5 2.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KDO28195.1 - 0.088 13.0 1.9 0.16 12.1 1.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 KDO28195.1 - 0.097 12.9 4.8 0.24 11.6 4.8 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KDO28195.1 - 0.2 11.8 1.4 0.3 11.2 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 KDO28195.1 - 0.59 10.4 6.0 3.7 7.8 6.0 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein RSRP PF17069.5 KDO28195.1 - 2.9 7.4 8.9 5 6.6 8.9 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SPRY PF00622.28 KDO28198.1 - 7.5e-08 32.5 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CorA PF01544.18 KDO28198.1 - 0.29 10.4 3.2 0.42 9.9 3.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 KDO28198.1 - 3.4 7.5 5.1 3.6 7.4 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator SPRY PF00622.28 KDO28199.1 - 1.8e-05 24.9 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain FH2 PF02181.23 KDO28199.1 - 0.029 13.5 0.8 0.04 13.0 0.8 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Jnk-SapK_ap_N PF09744.9 KDO28199.1 - 0.05 13.8 1.9 0.07 13.3 1.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HTH_16 PF12645.7 KDO28199.1 - 0.084 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Tweety PF04906.13 KDO28199.1 - 0.11 11.2 0.5 0.14 10.8 0.5 1.1 1 0 0 1 1 1 0 Tweety DUF2968 PF11180.8 KDO28199.1 - 4.2 7.0 11.1 11 5.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Cnd1 PF12717.7 KDO28200.1 - 2.8e-22 79.5 3.9 1.9e-16 60.6 0.1 4.9 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KDO28200.1 - 1.3e-05 24.5 1.0 5.7e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 KDO28200.1 - 0.00053 18.7 4.7 0.19 10.2 0.2 2.6 2 0 0 2 2 2 2 Adaptin N terminal region Nipped-B_C PF12830.7 KDO28200.1 - 0.004 17.1 0.8 0.089 12.7 0.3 3.5 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT PF02985.22 KDO28200.1 - 0.015 15.5 10.2 54 4.4 0.1 7.7 7 0 0 7 7 7 0 HEAT repeat UBA PF00627.31 KDO28201.1 - 4.8e-17 61.5 0.7 2.1e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KDO28201.1 - 0.0029 17.3 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.22 KDO28202.1 - 3.9e-24 84.2 0.0 3.6e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 KDO28202.1 - 2.9e-10 39.9 5.7 6.1e-10 38.8 5.7 1.6 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 KDO28202.1 - 1.2e-09 38.0 11.1 2.3e-09 37.1 11.1 1.3 1 0 0 1 1 1 1 OCRE domain zf-RanBP PF00641.18 KDO28202.1 - 0.00012 21.3 4.2 0.00021 20.5 4.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_jaz PF12171.8 KDO28202.1 - 0.0031 17.8 1.2 0.0072 16.6 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 KDO28202.1 - 0.015 15.4 1.4 0.037 14.1 1.4 1.6 1 0 0 1 1 1 0 G-patch domain zf-met PF12874.7 KDO28202.1 - 0.026 14.9 1.1 0.026 14.9 1.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PIH1 PF08190.12 KDO28205.1 - 1e-20 73.8 0.0 1.8e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain DUF3143 PF11341.8 KDO28205.1 - 0.014 15.7 0.1 0.029 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Beach PF02138.18 KDO28206.1 - 3.3e-78 262.8 0.0 5e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain ELMO_CED12 PF04727.13 KDO28206.1 - 3.1e-27 95.8 0.0 6.7e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family DUF4704 PF15787.5 KDO28206.1 - 5.4e-13 48.8 0.2 1.4e-12 47.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 KDO28206.1 - 5.6e-09 36.0 0.0 1.5e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KDO28206.1 - 7.6e-09 35.9 0.1 2.1e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily SPA PF08616.10 KDO28207.1 - 1.8e-28 98.8 0.0 3.4e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KDO28207.1 - 4e-13 50.0 0.0 9.4e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 KDO28207.1 - 1.1e-12 48.2 0.0 4.6e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KDO28207.1 - 5.2e-10 38.6 0.1 0.00015 20.6 0.0 3.4 1 1 1 2 2 2 2 Transport protein Avl9 Phtf-FEM1B_bdg PF12129.8 KDO28209.1 - 1.8e-15 57.1 1.0 3e-15 56.4 0.1 1.8 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor CytochromB561_N PF09786.9 KDO28209.1 - 0.082 11.9 2.1 0.14 11.1 2.1 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DAGK_cat PF00781.24 KDO28210.1 - 1e-25 89.8 0.0 1.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Myosin_head PF00063.21 KDO28211.1 - 1.3e-167 559.0 0.2 6.9e-124 414.5 0.0 4.0 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 KDO28211.1 - 0.047 13.9 0.1 0.47 10.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain HP0268 PF18618.1 KDO28211.1 - 0.086 13.3 0.3 0.68 10.4 0.3 2.7 1 0 0 1 1 1 0 HP0268 ABC_tran PF00005.27 KDO28211.1 - 0.64 10.5 0.0 0.64 10.5 0.0 3.8 3 1 0 3 3 3 0 ABC transporter Myosin_head PF00063.21 KDO28212.1 - 4.2e-160 534.2 1.9 2.9e-116 389.3 0.0 2.8 3 0 0 3 3 3 2 Myosin head (motor domain) Jnk-SapK_ap_N PF09744.9 KDO28212.1 - 0.0017 18.6 5.0 0.0017 18.6 5.0 8.0 2 1 5 8 8 7 1 JNK_SAPK-associated protein-1 Filament PF00038.21 KDO28212.1 - 0.0051 16.4 6.3 0.0051 16.4 6.3 6.1 1 1 5 6 6 4 3 Intermediate filament protein Fib_alpha PF08702.10 KDO28212.1 - 0.0079 16.4 1.3 0.0079 16.4 1.3 6.7 5 1 2 7 7 7 2 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 KDO28212.1 - 0.014 15.4 63.6 0.01 15.9 7.7 7.4 2 2 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 KDO28212.1 - 0.034 14.4 2.2 0.5 10.6 0.0 3.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KDO28212.1 - 0.29 11.7 0.0 0.29 11.7 0.0 3.5 4 1 0 4 4 4 0 ABC transporter IQ PF00612.27 KDO28212.1 - 0.47 10.4 9.2 1.7 8.7 0.5 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif PKcGMP_CC PF16808.5 KDO28212.1 - 1.8 8.5 5.2 1e+02 2.8 0.0 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HALZ PF02183.18 KDO28212.1 - 3.7 7.8 7.4 1.3 9.3 0.3 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KDO28212.1 - 8.5 6.9 14.0 15 6.1 0.4 6.2 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) zf-MYND PF01753.18 KDO28213.1 - 3.9e-11 42.8 45.6 2e-10 40.5 19.4 2.3 2 0 0 2 2 2 2 MYND finger Sigma70_ner PF04546.13 KDO28214.1 - 0.0037 17.2 4.3 0.0071 16.2 4.3 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region Utp14 PF04615.13 KDO28214.1 - 0.014 14.0 0.5 0.018 13.7 0.5 1.2 1 0 0 1 1 1 0 Utp14 protein RRN3 PF05327.11 KDO28214.1 - 0.038 12.5 3.4 0.075 11.6 3.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 KDO28214.1 - 0.047 13.3 1.7 0.092 12.4 1.7 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 KDO28214.1 - 0.36 10.9 8.5 1.6 8.7 8.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KDO28214.1 - 0.4 11.1 21.2 0.8 10.1 21.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO28214.1 - 0.78 9.0 19.9 1.3 8.3 19.9 1.3 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 KDO28214.1 - 3.3 7.2 6.8 6 6.4 6.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4611 PF15387.6 KDO28214.1 - 4.3 7.6 11.8 16 5.8 11.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 KDO28214.1 - 6.1 6.5 20.1 10 5.8 20.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PX PF00787.24 KDO28215.1 - 2e-18 66.4 0.0 4.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 PX domain zf-RING_2 PF13639.6 KDO28215.1 - 4.1e-08 33.4 7.2 8e-08 32.5 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KDO28215.1 - 4.9e-08 32.9 5.9 9.7e-08 31.9 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO28215.1 - 2.8e-07 30.4 7.1 5.7e-07 29.4 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO28215.1 - 7.8e-05 22.5 7.4 0.00014 21.6 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO28215.1 - 0.00012 21.9 5.8 0.00027 20.7 5.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KDO28215.1 - 0.00017 21.6 2.1 0.00017 21.6 2.1 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KDO28215.1 - 0.0008 19.2 4.0 0.0017 18.2 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KDO28215.1 - 0.0076 16.4 2.0 0.016 15.3 2.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KDO28215.1 - 0.011 15.5 8.2 0.028 14.2 8.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spc29 PF17082.5 KDO28215.1 - 0.034 14.0 1.1 0.063 13.1 1.1 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 FANCL_C PF11793.8 KDO28215.1 - 0.057 13.6 2.5 0.12 12.5 2.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KDO28215.1 - 0.07 12.9 3.9 0.16 11.7 3.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KDO28215.1 - 0.19 12.0 5.8 0.52 10.6 5.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KDO28215.1 - 0.27 11.1 3.4 0.62 9.9 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rep_4 PF05797.11 KDO28215.1 - 2.9 6.9 6.2 5.3 6.1 6.2 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF572 PF04502.13 KDO28215.1 - 8.9 5.8 9.2 18 4.8 9.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) IF-2B PF01008.17 KDO28216.1 - 2.7e-43 148.2 0.0 4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family ANF_receptor PF01094.28 KDO28216.1 - 0.11 11.5 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region DNA_pol_B PF00136.21 KDO28217.1 - 6.3e-139 463.6 0.0 8e-139 463.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KDO28217.1 - 7.8e-79 265.2 0.0 1.2e-78 264.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KDO28217.1 - 6.7e-19 68.1 5.5 1.3e-18 67.3 5.5 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta PKD_channel PF08016.12 KDO28218.1 - 6.5e-14 51.4 3.1 6.5e-14 51.4 3.1 1.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KDO28218.1 - 0.00036 19.9 10.9 0.00058 19.2 10.9 1.3 1 0 0 1 1 1 1 Ion transport protein Poty_coat PF00767.18 KDO28220.1 - 0.0067 16.0 0.2 0.0094 15.5 0.2 1.1 1 0 0 1 1 1 1 Potyvirus coat protein PH PF00169.29 KDO28224.1 - 4.9e-08 33.4 0.0 1.1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO28224.1 - 0.0075 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO28224.1 - 0.034 14.6 0.5 0.12 12.8 0.5 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PRK PF00485.18 KDO28225.1 - 0.74 9.5 3.5 0.88 9.3 0.4 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LMSTEN PF07988.12 KDO28225.1 - 2.7 7.5 5.2 8.2 6.0 0.1 3.1 3 0 0 3 3 3 0 LMSTEN motif CCDC92 PF14916.6 KDO28226.1 - 0.02 14.7 0.1 0.046 13.5 0.1 1.7 1 1 0 1 1 1 0 Coiled-coil domain of unknown function FUSC PF04632.12 KDO28226.1 - 0.034 12.7 8.0 0.037 12.6 8.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SurA_N PF09312.11 KDO28226.1 - 0.064 13.3 3.0 0.088 12.9 3.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Fibrillarin_2 PF10113.9 KDO28226.1 - 0.13 10.9 0.3 0.16 10.6 0.3 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein DUF4061 PF13270.6 KDO28226.1 - 0.88 9.9 9.2 0.27 11.6 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) NGP1NT PF08153.12 KDO28227.1 - 3.7e-46 156.5 0.0 6.4e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KDO28227.1 - 2.3e-17 63.1 0.1 2e-14 53.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO28227.1 - 1.8e-05 24.3 0.1 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO28227.1 - 4.8e-05 23.3 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KDO28227.1 - 0.0011 18.6 0.0 0.25 10.8 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KDO28227.1 - 0.011 15.8 2.5 0.1 12.6 0.1 3.3 2 2 0 2 2 2 0 Dynamin family Arf PF00025.21 KDO28227.1 - 0.015 14.7 0.2 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KDO28227.1 - 0.02 15.5 0.2 0.12 12.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 KDO28228.1 - 9.7e-55 185.8 0.0 1.3e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28228.1 - 9.7e-30 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-rbx1 PF12678.7 KDO28228.1 - 6.6e-05 23.1 10.2 0.00016 21.9 10.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KDO28228.1 - 0.00041 20.6 10.9 0.00095 19.5 10.9 1.7 1 0 0 1 1 1 1 Ring finger domain RIO1 PF01163.22 KDO28228.1 - 0.0008 19.1 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KDO28228.1 - 0.0012 17.7 0.0 0.0052 15.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase zf-ANAPC11 PF12861.7 KDO28228.1 - 0.0018 18.3 7.8 0.0042 17.1 7.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KDO28228.1 - 0.0053 16.6 10.0 0.0053 16.6 10.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO28228.1 - 0.021 14.7 5.0 0.053 13.4 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kdo PF06293.14 KDO28228.1 - 0.062 12.7 0.1 0.37 10.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO28228.1 - 0.072 13.0 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_11 PF17123.5 KDO28228.1 - 0.23 11.2 7.9 0.051 13.3 4.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger zinc_ribbon_16 PF17034.5 KDO28228.1 - 0.35 11.1 6.2 0.22 11.7 4.1 1.7 1 1 0 1 1 1 0 Zinc-ribbon like family zf-RING_5 PF14634.6 KDO28228.1 - 0.53 10.3 10.1 1.1 9.2 10.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO28228.1 - 0.66 9.9 7.7 1.3 8.9 7.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO28228.1 - 1.1 8.9 9.7 2.7 7.7 9.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EF-hand_1 PF00036.32 KDO28229.1 - 1.9e-17 61.4 0.4 3e-08 32.6 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO28229.1 - 1.9e-13 49.1 0.4 2.4e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KDO28229.1 - 8.2e-12 45.4 0.2 2.9e-11 43.7 0.1 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO28229.1 - 1.6e-11 43.2 5.3 5.3e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO28229.1 - 8.5e-05 22.3 8.8 0.0057 16.5 0.0 3.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.7 KDO28229.1 - 0.47 10.4 1.4 20 5.2 0.0 2.7 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Chibby PF14645.6 KDO28230.1 - 0.017 15.5 1.2 0.043 14.2 1.2 1.7 1 0 0 1 1 1 0 Chibby family APG6_N PF17675.1 KDO28230.1 - 0.065 13.8 5.0 0.18 12.3 5.0 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region PH PF00169.29 KDO28231.1 - 2.4e-12 47.3 0.1 4.3e-12 46.5 0.0 1.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KDO28231.1 - 0.01 16.2 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 KDO28231.1 - 0.05 13.4 0.1 0.16 11.8 0.0 1.7 1 1 1 2 2 2 0 Pleckstrin homology domain DPBB_1 PF03330.18 KDO28232.1 - 1.4e-05 25.3 0.8 4e-05 23.8 0.8 1.8 1 1 0 1 1 1 1 Lytic transglycolase DPBB_1 PF03330.18 KDO28233.1 - 1.3e-05 25.4 0.1 3.4e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Lytic transglycolase ECSCR PF15820.5 KDO28234.1 - 0.029 14.2 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Vpu PF00558.19 KDO28234.1 - 0.044 13.6 0.1 0.055 13.2 0.1 1.1 1 0 0 1 1 1 0 Vpu protein Tir_receptor_C PF07489.11 KDO28234.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DPBB_1 PF03330.18 KDO28235.1 - 0.00059 20.1 0.1 0.0015 18.7 0.1 1.7 1 0 0 1 1 1 1 Lytic transglycolase DUF2614 PF11023.8 KDO28235.1 - 0.15 12.1 0.7 0.4 10.8 0.2 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain AJAP1_PANP_C PF15298.6 KDO28235.1 - 6.9 6.8 9.8 0.55 10.4 5.0 1.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DPBB_1 PF03330.18 KDO28236.1 - 0.00025 21.3 0.1 0.00052 20.2 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase S1 PF00575.23 KDO28237.1 - 5.1e-51 170.9 18.5 3.3e-10 40.2 0.2 11.8 12 0 0 12 12 12 8 S1 RNA binding domain Suf PF05843.14 KDO28237.1 - 4.7e-08 33.4 16.4 6.9e-08 32.8 1.1 3.0 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KDO28237.1 - 7.7e-07 29.0 1.8 0.11 12.5 0.1 5.6 4 0 0 4 4 4 2 RNase II-type exonuclease C-terminal S1 domain TPR_15 PF13429.6 KDO28237.1 - 8.5e-06 25.2 0.6 8.5e-06 25.2 0.6 1.7 1 1 0 2 2 2 1 Tetratricopeptide repeat Nop14 PF04147.12 KDO28237.1 - 0.008 14.5 29.5 0.015 13.6 29.5 1.3 1 0 0 1 1 1 1 Nop14-like family SH3_3 PF08239.11 KDO28237.1 - 0.089 13.1 0.2 0.57 10.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain eIF2_C PF09173.11 KDO28237.1 - 0.13 12.5 0.5 2.6 8.4 0.0 3.5 3 0 0 3 3 3 0 Initiation factor eIF2 gamma, C terminal ProQ_C PF17516.2 KDO28237.1 - 0.56 9.7 5.3 14 5.2 0.0 3.9 3 0 0 3 3 3 0 ProQ C-terminal domain CDC45 PF02724.14 KDO28237.1 - 2.4 6.4 22.7 6.8 4.8 22.7 1.7 1 0 0 1 1 1 0 CDC45-like protein Mago-bind PF09282.10 KDO28238.1 - 1e-28 98.8 12.0 6.5e-15 54.7 1.7 2.6 2 0 0 2 2 2 2 Mago binding HSP70 PF00012.20 KDO28239.1 - 2.1e-99 333.4 3.7 2.1e-99 333.4 3.7 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KDO28239.1 - 1.3e-05 24.2 0.2 0.00014 20.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DAO PF01266.24 KDO28240.1 - 5.7e-35 121.5 2.0 6.5e-35 121.3 2.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KDO28240.1 - 0.041 13.4 0.2 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KDO28240.1 - 0.1 11.8 0.7 0.19 10.9 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KDO28240.1 - 0.13 12.5 1.7 0.2 11.9 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KDO28240.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ank_2 PF12796.7 KDO28241.1 - 9.7e-16 58.1 0.0 8.1e-07 29.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO28241.1 - 1.4e-15 56.9 0.0 9.8e-05 22.6 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO28241.1 - 1.3e-13 51.1 0.1 1.7e-07 31.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28241.1 - 2.6e-13 49.9 1.2 0.00013 22.2 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28241.1 - 2e-12 46.1 0.1 0.0014 19.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat HOIP-UBA PF16678.5 KDO28241.1 - 0.085 12.9 0.1 0.085 12.9 0.1 2.5 2 0 0 2 2 2 0 HOIP UBA domain pair BT1 PF03092.16 KDO28243.1 - 3.7e-57 193.7 16.7 7.2e-34 116.9 7.6 2.1 2 0 0 2 2 2 2 BT1 family SPC25 PF06703.11 KDO28244.1 - 3.3e-26 92.0 0.0 3.9e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) HORMA PF02301.18 KDO28245.1 - 2.3e-20 73.1 0.0 6e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KDO28245.1 - 0.051 13.4 0.0 0.23 11.3 0.0 2.0 2 1 0 2 2 2 0 Bacterial HORMA domain 2 GPI-anchored PF10342.9 KDO28246.1 - 2e-06 28.4 0.0 2.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Imm43 PF15570.6 KDO28246.1 - 0.05 13.6 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 43 FAD_binding_1 PF00667.20 KDO28247.1 - 2.2e-37 128.8 0.0 4.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KDO28247.1 - 7.6e-29 100.8 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KDO28247.1 - 2.7e-09 37.6 0.0 4.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Phlebovirus_NSM PF07246.11 KDO28248.1 - 0.032 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Nup35_RRM_2 PF14605.6 KDO28248.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aldedh PF00171.22 KDO28249.1 - 1.4e-157 524.9 1.3 1.6e-157 524.8 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KDO28249.1 - 0.052 13.0 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) WW PF00397.26 KDO28250.1 - 1.5e-32 111.3 51.1 1.3e-07 31.5 2.2 6.4 6 0 0 6 6 6 6 WW domain IQ PF00612.27 KDO28250.1 - 1.6e-25 86.4 58.1 0.0021 17.7 0.2 10.9 10 0 0 10 10 10 10 IQ calmodulin-binding motif LRR_4 PF12799.7 KDO28250.1 - 2.8e-15 56.2 0.0 0.1 13.1 0.0 7.0 4 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO28250.1 - 9.8e-08 31.5 20.3 0.54 10.5 1.2 9.3 11 0 0 11 11 11 3 Leucine Rich repeat Glyco_hyd_101C PF17451.2 KDO28250.1 - 6.1e-05 23.3 12.9 0.47 10.8 0.2 5.6 5 0 0 5 5 5 2 Glycosyl hydrolase 101 beta sandwich domain DUF938 PF06080.12 KDO28250.1 - 0.13 12.0 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) LRR_1 PF00560.33 KDO28250.1 - 0.18 12.5 9.9 41 5.3 0.1 6.6 7 2 0 7 7 7 0 Leucine Rich Repeat Na_H_Exchanger PF00999.21 KDO28251.1 - 4.9e-67 226.4 34.1 5.9e-67 226.1 34.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PX PF00787.24 KDO28252.1 - 2.6e-06 27.4 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 PX domain WH2 PF02205.20 KDO28252.1 - 2.5e-05 23.9 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 WH2 motif UL42 PF17638.2 KDO28252.1 - 0.95 9.5 6.3 26 4.8 0.0 2.5 2 0 0 2 2 2 0 HCMV UL42 CAP_N PF01213.19 KDO28252.1 - 1.8 7.9 7.6 3.7 6.9 7.2 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1116 PF06545.11 KDO28254.1 - 0.0058 16.1 0.1 0.0078 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) PH_9 PF15410.6 KDO28254.1 - 0.056 13.8 0.6 0.55 10.6 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain NuDC PF16273.5 KDO28255.1 - 0.1 13.1 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain Med11 PF10280.9 KDO28256.1 - 5.3e-06 26.9 0.2 6.2e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Mediator complex protein Flu_M1_C PF08289.11 KDO28256.1 - 0.002 18.3 0.4 0.0054 16.9 0.2 1.7 1 1 1 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain TINF2_N PF14973.6 KDO28256.1 - 0.047 14.0 0.1 0.069 13.5 0.1 1.3 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF5578 PF17741.1 KDO28257.1 - 2.5e-25 89.4 1.0 2.1e-23 83.1 1.0 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF5578) Peptidase_M13 PF01431.21 KDO28258.1 - 2.9e-67 226.3 0.0 3.6e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO28260.1 - 6e-38 130.5 0.0 6.8e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 DUF1515 PF07439.11 KDO28261.1 - 0.018 15.0 5.2 0.61 10.1 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) CK2S PF15011.6 KDO28261.1 - 0.074 12.9 2.1 0.14 12.0 0.3 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate Nuc_N PF14448.6 KDO28261.1 - 4.6 7.2 4.9 1.7 8.5 0.4 2.5 2 2 2 4 4 4 0 Nuclease N terminal zf-RING_UBOX PF13445.6 KDO28263.1 - 2.5e-10 40.2 6.2 2.6e-10 40.1 4.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO28263.1 - 6.4e-10 38.7 7.2 2.3e-09 36.9 7.5 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO28263.1 - 2.5e-09 37.1 7.6 5.8e-09 36.0 7.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KDO28263.1 - 9.9e-09 34.9 6.5 1.7e-08 34.2 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO28263.1 - 5.4e-07 29.9 9.1 9.5e-07 29.1 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO28263.1 - 2.3e-06 27.4 4.3 3.7e-06 26.7 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO28263.1 - 2.9e-06 27.2 4.7 7.7e-06 25.8 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KDO28263.1 - 5e-05 23.0 1.4 0.0001 22.0 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KDO28263.1 - 0.0075 16.1 5.5 0.041 13.7 5.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KDO28263.1 - 0.018 14.9 2.4 0.037 13.9 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.20 KDO28263.1 - 0.034 13.9 8.7 0.063 13.0 8.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 KDO28263.1 - 0.35 10.7 7.3 0.28 11.0 4.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KDO28263.1 - 0.37 11.1 8.1 0.92 9.8 8.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO28263.1 - 1.4 9.0 5.1 3.9 7.6 5.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SRP54 PF00448.22 KDO28264.1 - 2.9e-75 252.2 0.1 4.5e-75 251.6 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KDO28264.1 - 1.3e-26 93.1 0.5 1.3e-26 93.1 0.5 2.9 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 KDO28264.1 - 2.5e-18 66.0 0.9 4.9e-18 65.1 0.9 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KDO28264.1 - 4.3e-06 26.9 0.0 8.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO28264.1 - 1e-05 26.0 0.0 3.2e-05 24.4 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain cobW PF02492.19 KDO28264.1 - 0.00016 21.3 0.3 0.0014 18.2 0.3 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KDO28264.1 - 0.00018 21.3 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO28264.1 - 0.0018 18.6 0.0 0.0077 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 KDO28264.1 - 0.0022 17.5 0.3 3.2 7.2 0.1 3.0 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit Repressor_Mnt PF11423.8 KDO28264.1 - 0.0023 17.6 0.0 1.2 9.0 0.1 2.7 2 0 0 2 2 2 1 Regulatory protein Mnt MeaB PF03308.16 KDO28264.1 - 0.0049 15.9 0.0 0.029 13.3 0.0 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 KDO28264.1 - 0.0087 16.1 0.3 0.017 15.1 0.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CbiA PF01656.23 KDO28264.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KDO28264.1 - 0.019 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KDO28264.1 - 0.021 14.4 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region APS_kinase PF01583.20 KDO28264.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.14 KDO28264.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 KDO28264.1 - 0.041 14.0 0.4 0.36 10.9 0.4 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2209 PF09974.9 KDO28264.1 - 0.059 13.7 0.3 0.14 12.5 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_17 PF13207.6 KDO28264.1 - 0.064 13.7 2.7 0.11 13.0 0.1 2.6 3 1 0 3 3 2 0 AAA domain AAA_22 PF13401.6 KDO28264.1 - 0.079 13.2 0.1 0.22 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO28264.1 - 0.12 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KDO28264.1 - 0.19 11.0 0.2 0.41 9.9 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase zf-RING_2 PF13639.6 KDO28266.1 - 1.5e-10 41.2 9.8 2.4e-10 40.6 9.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO28266.1 - 2.3e-08 33.8 8.9 3.4e-08 33.2 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO28266.1 - 3.1e-08 33.8 7.2 5.9e-08 32.9 7.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO28266.1 - 6.7e-08 32.1 6.5 1.5e-07 31.0 6.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO28266.1 - 3.8e-07 30.0 6.7 6.1e-07 29.3 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO28266.1 - 6e-07 29.4 6.0 1.2e-06 28.4 6.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO28266.1 - 1.4e-06 28.1 8.2 2.2e-06 27.4 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO28266.1 - 1.2e-05 25.1 7.3 1.8e-05 24.5 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO28266.1 - 0.00041 20.1 8.0 0.00074 19.3 7.2 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO28266.1 - 0.0018 17.8 7.7 0.0028 17.2 7.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO28266.1 - 0.0063 16.5 6.3 0.063 13.3 6.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KDO28266.1 - 0.095 12.8 5.1 0.22 11.6 5.1 1.7 1 1 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 KDO28266.1 - 0.11 12.6 5.9 0.16 12.1 5.1 1.7 2 0 0 2 2 1 0 KIAA1045 RING finger BRE1 PF08647.11 KDO28266.1 - 0.12 12.5 1.3 0.21 11.7 1.3 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase zf-C3H2C3 PF17122.5 KDO28266.1 - 0.19 11.8 6.1 0.53 10.4 6.2 1.8 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 KDO28266.1 - 0.43 10.5 8.0 0.55 10.2 4.5 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rox3 PF08633.10 KDO28266.1 - 1 9.6 7.2 2 8.6 7.2 1.5 1 1 0 1 1 1 0 Rox3 mediator complex subunit FANCL_C PF11793.8 KDO28266.1 - 2.9 8.1 8.7 12 6.2 8.3 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain Aminotran_1_2 PF00155.21 KDO28267.1 - 4.7e-58 197.1 0.0 8.9e-58 196.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II PDT PF00800.18 KDO28267.1 - 8.4e-28 97.4 0.0 1.9e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Prephenate dehydratase DegT_DnrJ_EryC1 PF01041.17 KDO28267.1 - 0.0032 16.9 0.1 0.0064 15.8 0.1 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 KDO28267.1 - 0.0032 16.3 0.0 0.007 15.2 0.0 1.5 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_MocR PF12897.7 KDO28267.1 - 0.0059 15.5 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase CotJB PF12652.7 KDO28267.1 - 0.17 12.1 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 CotJB protein COPI_assoc PF08507.10 KDO28268.1 - 1.8e-05 24.8 0.8 2.3e-05 24.5 0.8 1.1 1 0 0 1 1 1 1 COPI associated protein Ion_trans PF00520.31 KDO28269.1 - 5.6e-33 114.2 25.4 1.9e-24 86.3 13.1 2.8 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 KDO28269.1 - 2.3e-26 91.5 16.3 1.5e-13 50.5 1.2 3.0 2 0 0 2 2 2 2 Ion channel PDZ_6 PF17820.1 KDO28270.1 - 1.7e-07 30.9 0.6 0.063 13.1 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 KDO28270.1 - 2e-05 24.8 0.0 0.00062 20.1 0.0 2.7 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KDO28270.1 - 0.024 15.0 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Mlh1_C PF16413.5 KDO28271.1 - 6.1e-68 229.1 0.1 1.3e-66 224.8 0.0 2.8 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KDO28271.1 - 1.1e-31 108.9 0.1 2.5e-31 107.8 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KDO28271.1 - 1.9e-11 43.9 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KDO28271.1 - 2e-05 25.1 0.0 5.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDCD2_C PF04194.13 KDO28272.1 - 1.6e-35 122.8 0.0 2.9e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain YL1_C PF08265.11 KDO28272.1 - 0.095 12.5 0.3 0.29 10.9 0.3 1.9 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Lzipper-MIP1 PF14389.6 KDO28273.1 - 0.0014 18.8 1.1 0.0014 18.8 1.1 2.3 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Csm1 PF12539.8 KDO28273.1 - 0.0044 17.6 0.0 0.0079 16.8 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Filament PF00038.21 KDO28273.1 - 0.011 15.3 12.3 0.061 12.9 12.3 1.9 1 1 1 2 2 2 0 Intermediate filament protein HALZ PF02183.18 KDO28273.1 - 0.037 14.3 1.0 0.037 14.3 1.0 3.1 3 0 0 3 3 2 0 Homeobox associated leucine zipper Choline_kinase PF01633.20 KDO28273.1 - 0.082 12.5 1.7 0.15 11.7 1.7 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4407 PF14362.6 KDO28273.1 - 0.34 10.2 9.7 0.47 9.8 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SFTA2 PF15210.6 KDO28273.1 - 0.49 10.4 1.7 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Surfactant-associated protein 2 Cnn_1N PF07989.11 KDO28273.1 - 0.52 10.5 9.3 5.6 7.2 0.1 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KDO28273.1 - 0.52 10.1 8.6 1.1 9.1 1.0 2.9 1 1 1 2 2 2 0 Septum formation initiator XhlA PF10779.9 KDO28273.1 - 0.65 10.2 3.3 0.89 9.8 1.7 2.1 1 1 0 1 1 1 0 Haemolysin XhlA Tup_N PF08581.10 KDO28273.1 - 0.7 10.2 6.2 0.92 9.9 4.0 2.3 2 1 0 2 2 2 0 Tup N-terminal Atg14 PF10186.9 KDO28273.1 - 0.79 8.8 11.3 1.2 8.1 11.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4813 PF16072.5 KDO28273.1 - 0.9 9.2 6.1 1.4 8.5 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF5094 PF17015.5 KDO28273.1 - 1 9.5 14.6 46 4.1 9.9 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) PCRF PF03462.18 KDO28273.1 - 1.1 9.1 11.2 2.5 7.9 10.7 1.9 1 1 0 1 1 1 0 PCRF domain WXG100 PF06013.12 KDO28273.1 - 1.2 9.5 6.1 1.9 8.8 4.4 2.3 3 0 0 3 3 1 0 Proteins of 100 residues with WXG Phage_GPO PF05929.11 KDO28273.1 - 1.7 8.2 13.7 6.1 6.4 12.6 2.2 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_DNA_bd PF12329.8 KDO28273.1 - 3.1 7.9 22.5 1.2e+02 2.8 17.4 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 KDO28273.1 - 7.4 7.1 11.8 2 8.9 1.6 3.0 1 1 2 3 3 3 0 Snapin/Pallidin DUF2408 PF10303.9 KDO28273.1 - 8.1 7.0 12.9 4.2 7.9 9.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) SOGA PF11365.8 KDO28273.1 - 9.2 7.5 12.8 1.5 10.0 7.7 2.5 2 1 1 3 3 2 0 Protein SOGA UPF0242 PF06785.11 KDO28273.1 - 9.7 6.2 17.1 45 4.1 17.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GCV_H PF01597.19 KDO28274.1 - 5e-06 26.4 0.0 8.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein zf-CCCH PF00642.24 KDO28274.1 - 0.0026 17.6 1.6 0.0026 17.6 1.6 1.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_16 PF10294.9 KDO28275.1 - 8.6e-27 94.0 0.0 1.3e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO28275.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO28275.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ABC_tran PF00005.27 KDO28276.1 - 2.5e-48 164.1 0.0 3.5e-27 95.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO28276.1 - 3.5e-42 144.9 29.6 2.6e-21 76.5 8.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO28276.1 - 1.9e-07 30.8 2.1 0.016 14.6 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO28276.1 - 2.4e-06 28.1 0.4 0.0085 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO28276.1 - 4e-06 26.9 0.3 0.052 13.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO28276.1 - 1.9e-05 24.6 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO28276.1 - 0.00032 20.4 0.5 0.6 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO28276.1 - 0.0032 17.3 0.8 4.6 7.0 0.1 3.9 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO28276.1 - 0.004 17.7 1.5 1.5 9.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KDO28276.1 - 0.006 16.3 1.5 1.8 8.3 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO28276.1 - 0.012 15.9 1.6 3.2 8.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO28276.1 - 0.021 14.0 2.6 1.2 8.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KDO28276.1 - 0.03 14.4 1.6 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 KDO28276.1 - 0.038 13.0 0.3 3.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KDO28276.1 - 0.045 13.3 0.5 6.6 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO28276.1 - 0.063 13.0 5.2 1.1 9.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO28276.1 - 0.069 12.4 0.7 1.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KDO28276.1 - 0.095 13.3 0.0 21 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KDO28276.1 - 0.12 12.0 0.1 0.46 10.2 0.0 2.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KDO28276.1 - 0.13 11.8 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KDO28276.1 - 0.16 12.4 0.3 46 4.4 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KDO28276.1 - 0.17 11.9 0.4 7.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KDO28276.1 - 0.21 12.0 0.1 35 4.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase cobW PF02492.19 KDO28276.1 - 0.21 11.1 0.8 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KDO28276.1 - 0.31 11.1 3.4 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain CPT PF07931.12 KDO28276.1 - 0.51 10.2 2.9 17 5.2 0.1 3.4 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 KDO28276.1 - 0.72 9.0 2.3 3.5 6.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) CPBP PF02517.16 KDO28277.1 - 1.1e-05 25.7 16.8 5.3e-05 23.5 16.8 2.4 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Peptidase_M76 PF09768.9 KDO28278.1 - 2.2e-55 187.0 8.3 2.5e-55 186.9 8.3 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KDO28278.1 - 0.0034 17.2 0.1 0.0043 16.9 0.1 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KDO28278.1 - 0.14 12.5 0.0 0.19 12.0 0.0 1.3 1 1 0 1 1 1 0 Effector protein WD40_3 PF15911.5 KDO28279.1 - 1.2e-16 60.5 0.0 1.1e-14 54.2 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28279.1 - 5.4e-12 45.8 0.2 0.062 13.6 0.1 5.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KDO28279.1 - 5.2e-07 29.6 1.1 0.76 9.6 0.1 3.8 2 1 1 3 3 3 3 Region in Clathrin and VPS TPR_7 PF13176.6 KDO28279.1 - 0.003 17.5 10.8 11 6.3 0.3 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat eIF2A PF08662.11 KDO28279.1 - 0.014 15.2 0.1 0.35 10.7 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KDO28279.1 - 0.025 15.4 2.8 6 7.9 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_14 PF13428.6 KDO28279.1 - 0.039 14.8 17.6 21 6.3 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KDO28279.1 - 0.057 12.5 10.1 0.52 9.3 2.9 3.7 4 0 0 4 4 4 0 Coatomer WD associated region PALB2_WD40 PF16756.5 KDO28279.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain zf-ribbon_3 PF13248.6 KDO28279.1 - 0.2 11.1 11.4 0.77 9.3 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain MIT PF04212.18 KDO28279.1 - 0.29 11.2 0.0 0.29 11.2 0.0 5.2 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KDO28279.1 - 0.89 9.9 18.7 84 3.8 0.1 7.9 7 1 1 8 8 8 0 Tetratricopeptide repeat DZR PF12773.7 KDO28279.1 - 1 9.4 6.5 12 6.0 6.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon RPN1_RPN2_N PF17781.1 KDO28280.1 - 1.5e-60 205.2 2.9 2.4e-60 204.5 2.9 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KDO28280.1 - 1.7e-30 104.8 0.0 4.1e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KDO28280.1 - 5.5e-29 99.1 25.0 6e-05 23.3 0.1 9.9 11 0 0 11 11 11 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KDO28280.1 - 6.2e-07 29.7 3.1 0.043 14.2 0.1 4.0 2 1 2 4 4 4 2 HEAT repeats IFRD PF05004.13 KDO28280.1 - 0.041 13.0 4.8 0.64 9.1 1.8 2.7 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) DSPc PF00782.20 KDO28281.1 - 6.9e-23 80.9 0.0 1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO28281.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TPR_19 PF14559.6 KDO28282.1 - 4.2e-05 24.0 0.3 4.2e-05 24.0 0.3 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3655 PF12379.8 KDO28282.1 - 0.047 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) TPR_16 PF13432.6 KDO28282.1 - 1.5 9.6 21.7 0.92 10.2 0.4 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 KDO28283.1 - 1.2e-61 204.6 4.9 1.4e-20 73.0 0.1 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein Complex1_LYR PF05347.15 KDO28284.1 - 8.8e-09 35.3 0.1 1.4e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO28284.1 - 3.8e-05 24.3 0.1 5.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KDO28284.1 - 0.017 15.7 0.1 0.039 14.5 0.1 1.6 2 0 0 2 2 2 0 Complex1_LYR-like HR1 PF02185.16 KDO28284.1 - 0.056 13.6 1.1 5.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Hr1 repeat PNPase PF03726.14 KDO28284.1 - 0.07 13.6 1.1 5.8 7.5 0.3 2.3 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PH PF00169.29 KDO28285.1 - 7.1e-10 39.3 0.4 1.6e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 PH domain DUF2981 PF11200.8 KDO28285.1 - 0.0061 16.3 2.4 0.0084 15.9 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) PH_11 PF15413.6 KDO28285.1 - 0.017 15.5 0.6 0.074 13.5 0.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain WASH_WAHD PF11945.8 KDO28285.1 - 0.037 13.6 2.6 0.071 12.6 2.6 1.4 1 0 0 1 1 1 0 WAHD domain of WASH complex COG5 PF10392.9 KDO28285.1 - 0.051 13.7 1.4 0.13 12.4 0.5 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 PH_8 PF15409.6 KDO28285.1 - 0.066 13.5 0.3 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF908 PF06012.12 KDO28285.1 - 0.084 12.3 6.8 0.0099 15.3 3.0 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Nup54 PF13874.6 KDO28285.1 - 0.12 12.5 2.0 0.29 11.2 2.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FAM76 PF16046.5 KDO28285.1 - 0.44 9.8 4.3 0.73 9.1 4.3 1.3 1 0 0 1 1 1 0 FAM76 protein Prefoldin_2 PF01920.20 KDO28285.1 - 2.2 8.3 8.0 0.46 10.5 2.0 2.3 2 1 0 2 2 2 0 Prefoldin subunit ATG16 PF08614.11 KDO28285.1 - 2.3 8.4 9.8 0.42 10.8 6.0 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 KDO28285.1 - 4 7.8 7.4 1 9.6 2.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HSF_DNA-bind PF00447.17 KDO28286.1 - 1.8e-18 66.9 2.9 3e-18 66.2 2.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding TANGO2 PF05742.12 KDO28287.1 - 1.9e-45 155.9 0.0 2.4e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 EVC2_like PF12297.8 KDO28288.1 - 0.0028 16.4 8.6 0.0045 15.7 8.5 1.4 1 1 0 1 1 1 1 Ellis van Creveld protein 2 like protein BssS PF13991.6 KDO28288.1 - 0.15 12.1 1.0 0.26 11.4 0.4 1.8 2 0 0 2 2 2 0 BssS protein family SlyX PF04102.12 KDO28288.1 - 0.16 12.6 1.2 0.16 12.6 1.2 2.4 2 1 0 2 2 2 0 SlyX DEAD PF00270.29 KDO28289.1 - 8.7e-43 146.1 0.0 1.2e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO28289.1 - 3.5e-29 101.4 1.6 4.1e-28 97.9 0.5 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KDO28289.1 - 0.00084 18.6 0.1 0.0012 18.1 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KDO28289.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 KDO28289.1 - 0.21 11.3 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KDO28290.1 - 1.6e-109 365.9 0.2 3e-109 365.0 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO28290.1 - 3.2e-23 82.3 0.0 9e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Imm51 PF15595.6 KDO28290.1 - 0.062 13.2 0.7 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 51 DUF5082 PF16888.5 KDO28290.1 - 0.084 13.2 7.4 0.44 10.8 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) M_domain PF12938.7 KDO28290.1 - 7 6.4 12.2 24 4.6 0.2 3.6 3 1 0 3 3 3 0 M domain of GW182 Thioredoxin_8 PF13905.6 KDO28291.1 - 2e-27 95.4 0.0 2.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO28291.1 - 6.7e-08 32.5 0.0 2.3e-06 27.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 KDO28291.1 - 2.5e-06 27.4 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO28291.1 - 0.00015 21.5 0.0 0.00018 21.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KDO28291.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 KDO28291.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 KDO28291.1 - 0.0016 18.8 0.0 0.0028 18.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO28291.1 - 0.027 14.7 0.1 0.12 12.6 0.1 1.9 2 1 0 2 2 2 0 Thioredoxin-like GILT PF03227.16 KDO28291.1 - 0.066 13.5 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Pkinase PF00069.25 KDO28292.1 - 6.1e-52 176.6 0.0 5.4e-48 163.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28292.1 - 7.9e-19 67.9 0.0 1.1e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 KDO28292.1 - 0.0085 15.7 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KDO28292.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SWIM PF04434.17 KDO28293.1 - 1.7e-05 24.3 0.1 4.7e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger wnt PF00110.19 KDO28294.1 - 0.0049 16.5 1.5 0.65 9.5 0.1 2.1 1 1 1 2 2 2 2 wnt family AP3D1 PF06375.11 KDO28295.1 - 0.064 13.5 6.8 0.15 12.3 6.8 1.7 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ThiD2 PF17792.1 KDO28296.1 - 0.5 10.8 4.4 6.2 7.3 2.0 2.6 1 1 1 2 2 2 0 ThiD2 family Malt_amylase_C PF16657.5 KDO28297.1 - 0.026 14.6 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Hydrolase_4 PF12146.8 KDO28297.1 - 0.05 12.9 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ILEI PF15711.5 KDO28297.1 - 0.063 13.8 0.1 0.12 12.8 0.0 1.5 2 0 0 2 2 2 0 Interleukin-like EMT inducer MMR_HSR1 PF01926.23 KDO28298.1 - 1.1e-13 51.3 0.1 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO28298.1 - 3.5e-06 26.6 0.1 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO28298.1 - 1.5e-05 25.0 0.1 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KDO28298.1 - 0.0082 15.5 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MeaB PF03308.16 KDO28298.1 - 0.025 13.5 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cwf_Cwc_15 PF04889.12 KDO28298.1 - 1.7 8.3 9.6 4.1 7.1 9.6 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KDO28298.1 - 5.3 6.3 8.1 11 5.3 8.1 1.4 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 KDO28299.1 - 1.6e-69 234.2 0.0 2e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28299.1 - 4e-40 137.8 0.0 5.1e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO28299.1 - 7.4e-09 35.3 0.0 6.3e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PH_3 PF14593.6 KDO28299.1 - 2.6e-08 33.9 0.0 4.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.23 KDO28299.1 - 8.8e-05 22.5 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO28299.1 - 0.002 17.5 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sushi_2 PF09014.10 KDO28299.1 - 0.0026 17.6 0.4 0.0049 16.7 0.4 1.5 1 0 0 1 1 1 1 Beta-2-glycoprotein-1 fifth domain Pox_ser-thr_kin PF05445.11 KDO28299.1 - 0.0085 15.1 0.2 0.029 13.3 0.0 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase DUF3379 PF11859.8 KDO28299.1 - 0.058 12.7 0.5 0.089 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) ABC1 PF03109.16 KDO28299.1 - 0.066 13.4 0.4 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 ABC1 family Seadorna_VP7 PF07387.11 KDO28299.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KDO28299.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 KDO28301.1 - 2.6e-33 114.4 4.9 2.4e-13 50.5 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28301.1 - 3.2e-31 107.3 3.8 3.1e-10 40.4 0.3 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28301.1 - 4.3e-25 85.0 6.6 0.00029 21.0 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 KDO28301.1 - 3.3e-23 81.1 14.1 0.00027 21.2 0.1 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KDO28301.1 - 3.5e-21 75.0 8.9 2.9e-05 24.3 0.9 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) GlcNAc PF11397.8 KDO28303.1 - 9.7e-54 183.1 1.9 2.6e-49 168.6 0.4 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) IQ PF00612.27 KDO28304.1 - 7e-07 28.5 6.2 0.00028 20.4 1.9 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif CaMBD PF02888.16 KDO28304.1 - 0.42 10.8 2.4 1.3 9.2 2.4 1.8 1 0 0 1 1 1 0 Calmodulin binding domain NACHT PF05729.12 KDO28305.1 - 3e-05 24.0 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KDO28305.1 - 0.001 19.6 0.0 0.0042 17.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KDO28305.1 - 0.0022 18.3 0.0 0.011 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KDO28305.1 - 0.0025 18.2 0.0 0.0077 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KDO28305.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 KDO28305.1 - 0.021 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 KDO28305.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase cobW PF02492.19 KDO28305.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 KDO28305.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KDO28305.1 - 0.086 13.2 3.2 0.17 12.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KDO28305.1 - 0.09 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KDO28305.1 - 0.12 12.8 0.0 0.45 10.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KDO28305.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Ribophorin_I PF04597.14 KDO28306.1 - 2.7e-127 425.6 1.6 3e-127 425.5 1.6 1.0 1 0 0 1 1 1 1 Ribophorin I OMP_b-brl_3 PF14905.6 KDO28306.1 - 0.09 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family eIF-3c_N PF05470.12 KDO28307.1 - 1e-140 470.0 47.9 4.5e-140 467.8 39.7 3.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KDO28307.1 - 2e-09 37.9 0.0 3.1e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 PCI domain SOGA PF11365.8 KDO28307.1 - 0.014 16.5 1.2 0.083 14.0 1.2 2.4 1 0 0 1 1 1 0 Protein SOGA CinA_KH PF18146.1 KDO28307.1 - 0.046 13.9 0.2 0.61 10.3 0.0 2.8 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Nop14 PF04147.12 KDO28307.1 - 0.28 9.3 30.5 0.68 8.1 30.5 1.7 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KDO28307.1 - 1.4 7.6 18.2 0.51 9.1 13.4 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Ribosomal_S9 PF00380.19 KDO28308.1 - 9.3e-47 158.5 0.9 1.5e-46 157.8 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 APG6_N PF17675.1 KDO28309.1 - 1.1e-05 26.0 18.1 0.001 19.6 6.3 2.0 1 1 1 2 2 2 2 Apg6 coiled-coil region CALCOCO1 PF07888.11 KDO28309.1 - 0.00075 18.5 15.3 0.022 13.6 4.7 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.15 KDO28309.1 - 0.0015 18.3 16.4 0.017 14.9 2.7 3.5 2 2 1 3 3 3 1 Septum formation initiator ATG16 PF08614.11 KDO28309.1 - 0.0029 17.8 18.4 0.098 12.9 7.0 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Microvir_H PF04687.12 KDO28309.1 - 0.0033 16.8 0.5 0.0057 16.1 0.5 1.4 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) DUF4407 PF14362.6 KDO28309.1 - 0.0061 16.0 11.2 0.0073 15.7 11.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Spc7 PF08317.11 KDO28309.1 - 0.007 15.3 16.7 0.12 11.3 6.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF724 PF05266.14 KDO28309.1 - 0.015 15.1 11.6 0.024 14.5 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 KDO28309.1 - 0.015 15.4 14.4 0.031 14.3 2.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KDO28309.1 - 0.018 15.0 10.6 0.42 10.6 1.2 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 KDO28309.1 - 0.023 14.8 16.1 0.74 9.9 6.6 2.9 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4795 PF16043.5 KDO28309.1 - 0.028 14.0 7.5 0.085 12.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 KDO28309.1 - 0.036 14.1 14.4 0.46 10.5 0.1 3.6 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KDO28309.1 - 0.043 14.3 12.7 0.25 11.8 0.9 3.1 2 1 0 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 KDO28309.1 - 0.053 12.8 13.1 0.18 11.1 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Taxilin PF09728.9 KDO28309.1 - 0.053 12.7 13.9 0.32 10.1 2.8 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein SlyX PF04102.12 KDO28309.1 - 0.057 14.1 10.2 1.8 9.3 0.4 3.4 2 1 1 3 3 3 0 SlyX O-FucT PF10250.9 KDO28309.1 - 0.097 12.3 1.2 0.1 12.2 1.2 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Fez1 PF06818.15 KDO28309.1 - 0.13 12.8 11.7 0.7 10.3 11.7 1.8 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.12 KDO28309.1 - 0.13 12.3 6.2 4.9 7.2 1.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KDO28309.1 - 0.13 12.3 11.6 4.4 7.3 11.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 KDO28309.1 - 0.14 12.4 12.7 0.14 12.3 3.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.12 KDO28309.1 - 0.19 11.3 22.7 5.7 6.4 22.7 2.6 1 1 0 1 1 1 0 PspA/IM30 family Sec34 PF04136.15 KDO28309.1 - 0.23 11.3 7.2 0.56 10.1 1.4 2.3 2 1 0 2 2 2 0 Sec34-like family Ax_dynein_light PF10211.9 KDO28309.1 - 0.24 11.3 12.5 0.53 10.2 1.6 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Tex_N PF09371.10 KDO28309.1 - 0.25 11.0 8.9 0.43 10.2 8.9 1.4 1 1 0 1 1 1 0 Tex-like protein N-terminal domain GAS PF13851.6 KDO28309.1 - 0.25 10.7 15.4 1.3 8.3 6.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KDO28309.1 - 0.4 10.9 5.1 16 5.6 0.3 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 KDO28309.1 - 0.67 9.0 12.4 1.2 8.1 10.6 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KDO28309.1 - 0.71 10.5 6.9 2.3e+02 2.5 7.1 2.6 1 1 0 1 1 1 0 Initiation control protein YabA LMBR1 PF04791.16 KDO28309.1 - 0.84 8.5 3.0 1 8.2 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CSN5_C PF18323.1 KDO28309.1 - 0.84 10.6 12.3 55 4.8 12.4 2.4 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Csm1_N PF18504.1 KDO28309.1 - 1.5 9.2 8.1 1.7 9.0 0.7 3.0 2 2 0 2 2 2 0 Csm1 N-terminal domain DUF5082 PF16888.5 KDO28309.1 - 2.2 8.6 11.2 7.3 6.9 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 KDO28309.1 - 2.3 8.5 11.3 1.4 9.2 1.9 2.5 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KDO28309.1 - 3.6 7.8 9.3 1.2 9.3 0.7 3.4 2 2 1 3 3 3 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KDO28309.1 - 4.3 7.4 20.9 8.1 6.5 5.0 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 KDO28309.1 - 7 6.4 19.9 19 5.0 19.9 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CENP-H PF05837.12 KDO28309.1 - 9.8 6.6 16.3 14 6.2 3.7 2.2 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Alba PF01918.21 KDO28310.1 - 4.1e-05 23.3 1.2 7.5e-05 22.5 1.2 1.4 1 0 0 1 1 1 1 Alba TruB_N PF01509.18 KDO28311.1 - 9.2e-47 159.1 0.0 1.3e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KDO28311.1 - 0.00049 20.2 0.8 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain DUF2694 PF10904.8 KDO28312.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) DPBB_1 PF03330.18 KDO28313.1 - 0.00094 19.4 0.2 0.0021 18.3 0.2 1.6 1 0 0 1 1 1 1 Lytic transglycolase PRCC PF10253.9 KDO28313.1 - 0.1 13.4 7.2 0.14 12.9 7.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4366 PF14283.6 KDO28313.1 - 0.67 10.0 1.8 7.4 6.6 1.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SOG2 PF10428.9 KDO28313.1 - 7.8 5.6 8.7 8.8 5.4 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ANTAR PF03861.14 KDO28314.1 - 0.013 15.3 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 ANTAR domain Ion_trans PF00520.31 KDO28315.1 - 4.9e-33 114.4 46.3 4.6e-20 71.9 19.0 2.3 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 KDO28315.1 - 0.004 17.6 0.2 0.01 16.2 0.2 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO28315.1 - 0.012 15.4 0.2 0.049 13.5 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KDO28315.1 - 0.014 14.9 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KDO28315.1 - 0.027 14.4 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Sigma_reg_N PF13800.6 KDO28315.1 - 7 7.0 8.0 38 4.7 0.5 3.8 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KDO28316.1 - 6.8e-40 136.8 34.9 4.6e-33 114.5 12.5 2.8 2 1 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 KDO28316.1 - 0.00021 21.7 0.4 0.00043 20.7 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO28316.1 - 0.0013 18.5 0.2 0.02 14.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO28316.1 - 0.0021 17.8 0.1 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KDO28316.1 - 0.0093 15.5 0.0 0.028 14.0 0.0 1.9 2 0 0 2 2 2 1 EF hand YrvL PF14184.6 KDO28316.1 - 0.24 11.5 10.0 0.082 13.0 2.1 3.5 3 0 0 3 3 3 0 Regulatory protein YrvL IBR PF01485.21 KDO28317.1 - 2.7e-15 56.3 40.8 3.4e-10 40.0 4.6 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KDO28317.1 - 0.00036 20.3 0.7 0.00036 20.3 0.7 4.4 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO28317.1 - 0.0046 16.9 2.7 0.0046 16.9 2.7 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KDO28317.1 - 0.013 15.8 30.3 0.2 12.0 7.4 4.7 3 1 0 3 3 3 0 Ring finger domain GAGA PF09237.11 KDO28317.1 - 1.3 8.9 6.6 3.9 7.4 0.1 3.1 2 0 0 2 2 2 0 GAGA factor RWD PF05773.22 KDO28318.1 - 4.7e-24 84.9 1.1 8.4e-24 84.1 1.1 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KDO28318.1 - 8.8e-06 26.1 1.9 8.8e-06 26.1 1.9 2.2 1 1 2 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Amino_oxidase PF01593.24 KDO28319.1 - 2.7e-45 155.5 0.0 3.3e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KDO28319.1 - 8e-12 45.2 0.1 1.7e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO28319.1 - 1.2e-06 28.0 0.0 0.0002 20.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO28319.1 - 0.00065 19.4 0.1 0.0011 18.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KDO28319.1 - 0.0023 18.0 0.8 0.015 15.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KDO28319.1 - 0.0059 15.5 1.1 0.0084 15.0 1.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KDO28319.1 - 0.04 14.5 1.2 0.17 12.5 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KDO28319.1 - 0.04 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 MCRA family AlaDh_PNT_C PF01262.21 KDO28319.1 - 0.051 12.9 0.6 0.091 12.0 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KDO28319.1 - 0.08 12.2 0.4 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KDO28319.1 - 0.16 11.0 3.6 0.2 10.7 2.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KDO28319.1 - 0.23 10.1 0.7 6.2 5.4 0.6 2.5 3 0 0 3 3 3 0 HI0933-like protein CFAP91 PF14738.6 KDO28320.1 - 5.4e-58 195.4 7.2 5.4e-58 195.4 7.2 3.0 3 0 0 3 3 3 1 Cilia- and flagella-associated protein 91 TrbI_Ftype PF09677.10 KDO28320.1 - 1.1 9.7 15.5 3 8.2 2.5 4.2 3 1 1 4 4 4 0 Type-F conjugative transfer system protein (TrbI_Ftype) Acetyltransf_9 PF13527.7 KDO28321.1 - 5.6e-16 58.8 0.2 6.6e-15 55.3 0.1 2.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO28321.1 - 9.2e-07 29.2 0.0 7.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO28321.1 - 3.7e-05 23.9 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO28321.1 - 0.0024 17.8 0.0 0.09 12.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KDO28321.1 - 0.012 15.6 0.1 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KDO28321.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KDO28321.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase Ccdc124 PF06244.12 KDO28322.1 - 5.3e-30 104.6 27.8 4.2e-28 98.5 27.8 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KDO28322.1 - 0.0032 17.9 0.2 0.0032 17.9 0.2 2.6 2 1 1 3 3 3 1 HMG (high mobility group) box DUF3889 PF13028.6 KDO28322.1 - 0.065 13.2 0.1 0.065 13.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3889) Use1 PF09753.9 KDO28323.1 - 6.8e-18 65.3 0.1 1.2e-17 64.5 0.1 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 CENP-F_leu_zip PF10473.9 KDO28323.1 - 0.064 13.3 1.8 0.16 12.0 1.8 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC-167 PF15188.6 KDO28323.1 - 0.42 11.0 3.7 33 4.9 3.7 3.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2937 PF11157.8 KDO28323.1 - 1.5 8.5 5.5 0.76 9.5 3.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) ABC_membrane PF00664.23 KDO28325.1 - 1.4e-61 208.6 17.1 3.9e-37 128.4 3.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO28325.1 - 2.9e-48 163.9 0.0 8.5e-28 97.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO28325.1 - 9.8e-12 44.8 3.9 0.0041 16.6 0.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO28325.1 - 3.8e-06 27.0 0.1 0.047 13.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO28325.1 - 4.3e-06 26.4 0.1 0.075 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO28325.1 - 0.00017 21.5 0.6 0.21 11.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO28325.1 - 0.00019 21.4 0.4 0.44 10.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO28325.1 - 0.00032 21.1 6.7 0.081 13.3 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 KDO28325.1 - 0.00049 19.2 0.5 0.23 10.5 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 KDO28325.1 - 0.00075 19.8 1.6 0.18 12.1 0.1 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KDO28325.1 - 0.0014 17.9 0.1 1.2 8.4 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.23 KDO28325.1 - 0.0017 18.4 2.3 0.52 10.3 0.1 2.6 2 0 0 2 2 2 2 Dynamin family IstB_IS21 PF01695.17 KDO28325.1 - 0.0028 17.4 1.9 3.2 7.4 0.0 3.4 4 0 0 4 4 4 2 IstB-like ATP binding protein DUF87 PF01935.17 KDO28325.1 - 0.013 15.6 2.4 0.1 12.7 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KDO28325.1 - 0.017 15.6 0.0 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KDO28325.1 - 0.022 14.4 1.3 0.87 9.1 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KDO28325.1 - 0.029 13.9 0.1 7.6 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 KDO28325.1 - 0.031 13.2 0.7 5.4 5.8 0.1 2.5 2 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KDO28325.1 - 0.031 13.5 0.6 1.3 8.1 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_18 PF13238.6 KDO28325.1 - 0.032 14.8 0.0 4.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO28325.1 - 0.04 14.1 1.5 0.62 10.2 0.2 2.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KDO28325.1 - 0.043 13.6 0.4 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KDO28325.1 - 0.046 14.0 0.1 8.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KDO28325.1 - 0.084 11.8 0.9 0.27 10.2 0.2 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KDO28325.1 - 0.085 12.9 0.2 6.7 6.7 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KDO28325.1 - 0.14 11.3 0.1 0.69 9.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KDO28325.1 - 0.15 11.4 1.1 7.3 5.9 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family S-AdoMet_synt_C PF02773.16 KDO28325.1 - 0.19 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain AAA_30 PF13604.6 KDO28325.1 - 0.22 11.2 4.6 12 5.6 0.1 3.3 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KDO28325.1 - 0.4 10.6 0.0 0.4 10.6 0.0 3.6 5 0 0 5 5 2 0 NACHT domain NTPase_1 PF03266.15 KDO28325.1 - 3.2 7.7 4.7 33 4.3 0.1 3.5 4 0 0 4 4 4 0 NTPase MFS_MOT1 PF16983.5 KDO28325.1 - 4.5 7.7 11.9 0.19 12.2 0.2 4.1 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Arrestin_N PF00339.29 KDO28328.1 - 5.8e-16 58.9 0.2 4.3e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KDO28328.1 - 1.1e-14 55.1 0.0 1.1e-10 42.1 0.0 2.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KDO28328.1 - 0.02 14.6 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like Rgp1 PF08737.10 KDO28328.1 - 0.11 11.6 1.1 2 7.5 0.1 2.5 2 1 1 3 3 3 0 Rgp1 Arrestin_N PF00339.29 KDO28329.1 - 1.7e-16 60.6 0.0 1.2e-13 51.3 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KDO28329.1 - 6.5e-08 33.1 0.0 1.8e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KDO28329.1 - 0.00025 20.8 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like DUF2574 PF10836.8 KDO28329.1 - 0.037 13.9 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Rgp1 PF08737.10 KDO28329.1 - 0.073 12.2 0.6 0.24 10.6 0.1 2.0 3 0 0 3 3 3 0 Rgp1 Arrestin_N PF00339.29 KDO28330.1 - 2.3e-17 63.4 0.0 3.4e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KDO28330.1 - 2.1e-13 50.9 0.0 6.3e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain nlz1 PF12402.8 KDO28330.1 - 0.05 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 Arrestin_C PF02752.22 KDO28331.1 - 7.7e-10 39.3 0.0 2.1e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain CENP-T_C PF15511.6 KDO28334.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO28334.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO28334.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO28334.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO28334.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO28334.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO28334.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KDO28335.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO28335.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO28335.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO28335.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO28335.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO28335.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO28335.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KDO28336.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KDO28336.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO28336.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO28336.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KDO28336.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO28336.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PFK PF00365.20 KDO28337.1 - 2.6e-56 191.1 0.3 3.4e-56 190.6 0.3 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 KDO28337.1 - 0.02 14.5 0.1 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KDO28337.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Methyltransf_16 PF10294.9 KDO28338.1 - 3.2e-22 79.1 0.0 4.7e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase 6PF2K PF01591.18 KDO28339.1 - 7e-63 211.9 0.0 9.9e-63 211.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KDO28339.1 - 7.3e-36 123.7 0.0 1.2e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AMPK1_CBM PF16561.5 KDO28339.1 - 2.2e-21 75.9 0.0 4.2e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AAA_33 PF13671.6 KDO28339.1 - 1.5e-06 28.4 0.0 4.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain CBM_48 PF02922.18 KDO28339.1 - 0.0033 17.8 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) KTI12 PF08433.10 KDO28339.1 - 0.0042 16.6 0.2 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 KDO28339.1 - 0.0099 16.1 0.3 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO28339.1 - 0.026 14.9 0.0 0.077 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KDO28339.1 - 0.038 14.1 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Torsin AAA_18 PF13238.6 KDO28339.1 - 0.043 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.12 KDO28340.1 - 5.9e-32 109.4 14.0 4.4e-07 30.4 0.2 6.2 6 0 0 6 6 6 6 Sel1 repeat TPR_6 PF13174.6 KDO28340.1 - 1.5 9.6 6.1 2.5 8.9 0.1 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SET PF00856.28 KDO28341.1 - 1.6e-09 38.3 0.0 6.7e-09 36.4 0.0 2.1 3 0 0 3 3 3 1 SET domain FYVE PF01363.21 KDO28341.1 - 3.5e-05 23.9 15.1 3.5e-05 23.9 15.1 2.5 3 0 0 3 3 3 1 FYVE zinc finger TPR_1 PF00515.28 KDO28341.1 - 4e-05 23.2 0.8 0.0028 17.4 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28341.1 - 7.6e-05 22.5 6.6 0.0023 17.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 KDO28343.1 - 1.5e-09 37.9 0.5 3e-09 36.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KDO28343.1 - 7.7e-07 29.4 5.2 8.6e-05 22.8 1.7 2.3 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.12 KDO28343.1 - 8.7e-06 25.3 1.0 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 KDO28343.1 - 0.0012 18.8 2.4 0.0012 18.8 2.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO28343.1 - 0.0042 16.9 5.0 0.53 10.2 2.7 2.6 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO28343.1 - 0.031 14.4 1.4 0.086 13.0 1.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 KDO28343.1 - 0.069 13.0 6.6 0.062 13.2 2.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO28343.1 - 0.079 12.9 4.9 0.26 11.3 2.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KDO28343.1 - 0.53 10.5 5.7 2.2 8.5 5.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KDO28343.1 - 0.6 10.0 9.1 0.1 12.5 3.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO28343.1 - 1 9.2 7.9 0.55 10.1 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TALPID3 PF15324.6 KDO28345.1 - 0.066 10.9 0.5 0.07 10.8 0.5 1.0 1 0 0 1 1 1 0 Hedgehog signalling target P33MONOX PF15302.6 KDO28345.1 - 0.08 12.6 0.7 0.099 12.3 0.7 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase Aminotran_1_2 PF00155.21 KDO28346.1 - 3.5e-53 181.1 0.0 4.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KDO28346.1 - 0.0038 15.8 0.0 0.017 13.6 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KDO28346.1 - 0.0053 15.8 0.0 0.048 12.6 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 KDO28346.1 - 0.01 14.7 0.0 0.13 11.0 0.0 2.6 2 1 0 2 2 2 0 Alanine-glyoxylate amino-transferase zf-HC5HC2H_2 PF13832.6 KDO28347.1 - 2.6e-20 72.6 4.9 2.6e-20 72.6 4.9 2.7 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO28347.1 - 6.9e-17 61.5 0.3 6.9e-17 61.5 0.3 3.3 1 1 2 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KDO28347.1 - 9.1e-12 44.3 3.9 9.1e-12 44.3 3.9 4.0 5 0 0 5 5 5 1 PHD-finger ZZ PF00569.17 KDO28347.1 - 6.3e-09 35.5 7.5 6.3e-09 35.5 7.5 3.2 5 0 0 5 5 5 1 Zinc finger, ZZ type PHD PF00628.29 KDO28347.1 - 1.8e-08 34.2 7.3 1.8e-08 34.2 7.3 4.4 4 1 0 4 4 4 3 PHD-finger zf-PHD-like PF15446.6 KDO28347.1 - 0.0026 17.4 1.6 0.0026 17.4 1.6 2.7 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KDO28347.1 - 0.01 15.7 1.2 0.01 15.7 1.2 5.0 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KDO28347.1 - 0.014 15.6 0.8 0.014 15.6 0.8 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger C1_2 PF03107.16 KDO28347.1 - 0.83 10.0 37.7 0.034 14.5 2.0 4.2 4 1 1 5 5 5 0 C1 domain ResIII PF04851.15 KDO28348.1 - 3e-22 79.4 0.0 5.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO28348.1 - 9e-19 67.9 0.1 2.2e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO28348.1 - 9.1e-17 61.4 0.0 3.4e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KDO28348.1 - 0.023 14.4 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase zf-RanBP PF00641.18 KDO28348.1 - 0.093 12.1 1.5 0.21 10.9 1.5 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF4203 PF13886.6 KDO28349.1 - 1.5e-35 122.7 32.1 2.2e-35 122.1 32.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3482 PF11981.8 KDO28349.1 - 2.3 7.5 3.4 3.7 6.9 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF4407 PF14362.6 KDO28349.1 - 3.9 6.7 8.3 9.9 5.4 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 KDO28350.1 - 2.8e-38 131.4 0.0 4.5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO28350.1 - 1.8e-25 89.4 0.0 2.7e-23 82.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO28350.1 - 5.2e-05 23.3 0.0 9.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KDO28350.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF374 PF04028.13 KDO28350.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Glyco_trans_2_3 PF13632.6 KDO28351.1 - 1.1e-16 61.4 0.0 1.1e-16 61.4 0.0 2.9 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 KDO28351.1 - 2.4e-14 52.8 4.5 6.4e-10 38.2 0.1 2.6 2 1 1 3 3 3 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 KDO28351.1 - 4.2e-09 36.6 0.0 0.00022 21.2 0.0 2.5 1 1 0 2 2 2 2 Glycosyltransferase like family 2 PH PF00169.29 KDO28351.1 - 7.5e-09 36.1 0.1 3.2e-08 34.0 0.1 2.2 2 0 0 2 2 2 1 PH domain Glycos_transf_2 PF00535.26 KDO28351.1 - 1.9e-08 34.3 0.0 0.037 13.8 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KDO28351.1 - 5.6e-05 22.7 0.0 0.0044 16.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 PH_8 PF15409.6 KDO28351.1 - 0.0092 16.2 1.9 0.28 11.5 1.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 KDO28351.1 - 0.013 15.8 8.8 0.013 15.8 8.8 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 KDO28351.1 - 0.21 12.0 4.3 0.81 10.1 4.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Glyco_trans_2_3 PF13632.6 KDO28352.1 - 4.8e-17 62.5 0.0 4.8e-17 62.5 0.0 2.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 KDO28352.1 - 1.5e-16 60.1 7.6 1.1e-12 47.4 0.8 3.0 2 1 1 3 3 3 2 Cellulose synthase PH PF00169.29 KDO28352.1 - 3.6e-09 37.1 0.1 9.7e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 PH domain Glycos_transf_2 PF00535.26 KDO28352.1 - 7e-09 35.7 0.0 0.042 13.7 0.0 3.5 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KDO28352.1 - 8.9e-09 35.6 0.0 0.00038 20.4 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KDO28352.1 - 2.4e-06 27.1 0.0 0.00011 21.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 zf-C6H2 PF15801.5 KDO28352.1 - 0.0018 18.6 11.0 0.0018 18.6 11.0 2.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding PH_8 PF15409.6 KDO28352.1 - 0.0046 17.2 0.7 0.03 14.6 0.7 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO28352.1 - 0.034 14.6 0.2 0.098 13.1 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Gemin6 PF06372.12 KDO28353.1 - 2.8e-09 36.7 0.0 3.5e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Gemin6 protein DUF2062 PF09835.9 KDO28355.1 - 2.7e-12 46.8 8.8 3.4e-12 46.5 8.8 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) TMEM208_SND2 PF05620.11 KDO28355.1 - 0.6 9.9 2.9 0.82 9.4 2.9 1.3 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Sugar_tr PF00083.24 KDO28356.1 - 2.9e-117 392.3 24.9 3.8e-89 299.6 12.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO28356.1 - 2.6e-37 128.6 34.5 5.6e-34 117.6 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 KDO28356.1 - 0.0049 17.4 6.5 0.0077 16.7 6.5 1.3 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 KDO28356.1 - 0.11 12.3 1.4 0.19 11.5 1.4 1.3 1 0 0 1 1 1 0 Integrin plexin domain Rick_17kDa_Anti PF05433.15 KDO28356.1 - 0.18 11.7 4.3 0.56 10.1 4.3 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF2530 PF10745.9 KDO28356.1 - 7.5 6.9 6.9 16 5.8 0.5 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) COG4 PF08318.12 KDO28357.1 - 1.1e-29 103.7 0.0 1.6e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 KDO28357.1 - 0.00037 19.5 0.0 0.00069 18.6 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec15 PF04091.12 KDO28357.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Yip1 PF04893.17 KDO28358.1 - 6.6e-16 58.5 17.2 8.6e-16 58.1 17.2 1.2 1 0 0 1 1 1 1 Yip1 domain Globin PF00042.22 KDO28359.1 - 0.00019 22.0 0.6 0.0012 19.4 0.5 2.3 2 1 0 2 2 2 1 Globin Arf PF00025.21 KDO28363.1 - 2.9e-30 105.0 0.0 4.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO28363.1 - 7.6e-08 31.9 0.0 0.00019 20.7 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit SRPRB PF09439.10 KDO28363.1 - 7.4e-06 25.5 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KDO28363.1 - 9.8e-06 25.8 0.0 3.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KDO28363.1 - 6.7e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KDO28363.1 - 0.00013 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Ras family ABC_tran PF00005.27 KDO28363.1 - 0.0045 17.5 0.1 0.012 16.1 0.1 1.7 1 0 0 1 1 1 1 ABC transporter Apolipoprotein PF01442.18 KDO28363.1 - 0.0079 16.1 3.8 0.0084 16.0 1.1 2.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain AAA_16 PF13191.6 KDO28363.1 - 0.0082 16.5 0.1 0.018 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KDO28363.1 - 0.021 14.4 0.0 0.064 12.8 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KDO28363.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 KDO28363.1 - 0.097 12.3 0.3 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KDO28363.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dpy-30 PF05186.13 KDO28363.1 - 0.15 11.8 0.1 0.5 10.1 0.1 2.0 1 0 0 1 1 1 0 Dpy-30 motif RasGEF PF00617.19 KDO28364.1 - 1.1e-18 68.0 0.0 1.8e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain Actin PF00022.19 KDO28365.1 - 5e-96 321.8 0.0 3.5e-94 315.7 0.0 2.0 1 1 0 1 1 1 1 Actin Auxin_resp PF06507.13 KDO28365.1 - 0.073 13.3 0.3 28 5.1 0.0 3.1 3 1 1 4 4 4 0 Auxin response factor Phage_pRha PF09669.10 KDO28365.1 - 0.08 13.5 0.1 7.8 7.1 0.0 3.0 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) BT1 PF03092.16 KDO28366.1 - 1.2e-12 46.9 7.4 2.1e-09 36.2 2.0 3.2 3 0 0 3 3 3 3 BT1 family BT1 PF03092.16 KDO28367.1 - 1e-11 43.8 10.9 1.2e-08 33.6 1.2 3.3 2 2 1 3 3 3 3 BT1 family HUN PF08729.10 KDO28367.1 - 0.032 14.2 0.8 0.057 13.4 0.8 1.3 1 0 0 1 1 1 0 HPC2 and ubinuclein domain PHD PF00628.29 KDO28368.1 - 6.8e-08 32.3 30.5 7.7e-05 22.5 2.6 4.0 3 0 0 3 3 3 3 PHD-finger zf-C2H2_6 PF13912.6 KDO28368.1 - 2.4 8.3 0.0 2.4 8.3 0.0 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger DUF4618 PF15397.6 KDO28369.1 - 0.089 12.2 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Cellulase PF00150.18 KDO28370.1 - 7.1e-28 97.8 3.6 7.9e-27 94.4 2.4 2.4 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) RAMP4 PF06624.12 KDO28370.1 - 0.027 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 BCAS2 PF05700.11 KDO28371.1 - 4e-35 121.4 2.5 4.5e-35 121.2 2.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) APC1_C PF18122.1 KDO28371.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Prim-Pol PF09250.11 KDO28371.1 - 0.16 12.3 0.4 7 7.0 0.5 2.5 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal SSP160 PF06933.11 KDO28372.1 - 0.0086 14.3 0.6 0.012 13.9 0.6 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 KDO28372.1 - 0.31 11.0 2.5 0.6 10.1 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YCII PF03795.14 KDO28373.1 - 1e-05 25.8 0.0 1.4e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Epimerase PF01370.21 KDO28374.1 - 3.1e-25 89.0 0.0 4.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KDO28374.1 - 5.3e-20 72.1 0.0 4.8e-17 62.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KDO28374.1 - 4.5e-12 45.7 0.0 6.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KDO28374.1 - 5.1e-10 38.8 0.0 7.1e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KDO28374.1 - 7.3e-09 35.2 0.0 3.4e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KDO28374.1 - 8.2e-07 28.4 0.0 9.5e-06 25.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KDO28374.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding MULE PF10551.9 KDO28375.1 - 9.1e-05 22.8 0.0 0.00031 21.1 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Pkinase PF00069.25 KDO28376.1 - 5e-64 216.2 0.0 6.9e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28376.1 - 1.7e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO28376.1 - 0.00023 21.2 0.0 0.0019 18.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO28376.1 - 0.0056 16.0 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KDO28376.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4586 PF15239.6 KDO28378.1 - 0.0061 16.8 0.6 0.01 16.1 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) zf-RING_2 PF13639.6 KDO28379.1 - 1.2e-09 38.3 9.9 1.7e-09 37.8 9.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO28379.1 - 5.8e-08 32.9 6.0 9e-08 32.3 6.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO28379.1 - 4.8e-06 26.2 8.0 9.1e-06 25.3 8.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO28379.1 - 8.7e-06 25.5 8.7 1.2e-05 25.0 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO28379.1 - 9.1e-06 25.6 2.9 1.4e-05 25.0 2.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO28379.1 - 0.0032 17.5 3.6 0.0032 17.5 3.6 1.6 1 1 1 2 2 2 1 RING-type zinc-finger SAP PF02037.27 KDO28379.1 - 0.0072 16.1 0.4 0.014 15.2 0.4 1.3 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 KDO28379.1 - 0.013 15.3 11.7 0.029 14.2 11.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO28379.1 - 0.015 15.3 7.9 0.022 14.7 7.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO28379.1 - 0.029 14.3 6.4 0.052 13.4 6.4 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO28379.1 - 0.12 12.0 5.9 0.2 11.3 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 KDO28379.1 - 0.15 12.2 3.6 0.26 11.5 3.6 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain Rad50_zn_hook PF04423.14 KDO28379.1 - 0.16 11.9 1.9 0.17 11.7 0.3 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RVT PF13966.6 KDO28379.1 - 0.64 10.8 2.7 15 6.4 0.3 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase RINGv PF12906.7 KDO28379.1 - 0.82 9.8 8.7 1.5 9.0 8.7 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO28379.1 - 1.5 9.0 9.8 4 7.7 9.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Acyltransferase PF01553.21 KDO28380.1 - 9.2e-14 51.2 0.0 1.4e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Chromo PF00385.24 KDO28382.1 - 9.1e-09 35.1 3.6 2.4e-08 33.8 3.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_1 PF01527.20 KDO28382.1 - 0.043 14.1 1.5 0.052 13.9 0.1 1.9 2 1 0 2 2 2 0 Transposase ABC_tran PF00005.27 KDO28384.1 - 1e-40 139.4 0.0 1.7e-20 74.0 0.1 3.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO28384.1 - 1.2e-10 41.8 0.0 0.0086 15.9 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO28384.1 - 1.9e-10 40.6 2.1 0.001 18.6 0.0 3.8 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KDO28384.1 - 1.2e-07 31.5 1.1 2.6e-07 30.4 1.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KDO28384.1 - 3.6e-07 30.9 3.0 0.0051 17.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO28384.1 - 1.1e-06 28.3 0.1 0.042 13.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO28384.1 - 2.3e-06 27.7 0.0 0.068 13.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KDO28384.1 - 3.4e-06 27.4 0.0 0.091 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain 4HB PF17947.1 KDO28384.1 - 6.3e-06 26.2 0.0 0.00013 22.0 0.0 2.9 2 0 0 2 2 2 1 Four helical bundle domain AAA_22 PF13401.6 KDO28384.1 - 7.4e-06 26.3 0.0 0.34 11.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KDO28384.1 - 1.2e-05 25.3 0.5 0.055 13.2 0.0 2.9 4 0 0 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.22 KDO28384.1 - 1.8e-05 25.0 0.3 0.14 12.5 0.0 3.5 4 0 0 4 4 3 2 RNA helicase RsgA_GTPase PF03193.16 KDO28384.1 - 2.9e-05 24.0 0.1 0.088 12.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 KDO28384.1 - 0.00011 22.7 0.0 0.21 12.0 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KDO28384.1 - 0.00037 20.7 0.0 0.54 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO28384.1 - 0.00053 20.5 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KDO28384.1 - 0.0012 18.8 0.1 0.24 11.3 0.1 2.8 2 1 0 2 2 2 1 NACHT domain MeaB PF03308.16 KDO28384.1 - 0.002 17.2 0.2 0.81 8.6 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 KDO28384.1 - 0.002 17.4 0.0 2.1 7.4 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_27 PF13514.6 KDO28384.1 - 0.0024 17.5 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO28384.1 - 0.0042 16.8 0.5 1.5 8.5 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_16 PF13191.6 KDO28384.1 - 0.0052 17.2 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KDO28384.1 - 0.0065 16.4 0.1 0.59 10.0 0.0 3.1 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KDO28384.1 - 0.0071 16.3 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KDO28384.1 - 0.0074 15.8 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KDO28384.1 - 0.011 15.0 0.0 0.39 9.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 KDO28384.1 - 0.015 15.3 0.0 3.7 7.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 KDO28384.1 - 0.015 15.3 0.0 0.24 11.5 0.0 2.6 3 0 0 3 3 2 0 Dynamin family DUF815 PF05673.13 KDO28384.1 - 0.016 14.4 0.0 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KDO28384.1 - 0.016 14.9 0.4 0.41 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KDO28384.1 - 0.023 14.4 0.1 9.5 6.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KDO28384.1 - 0.027 14.6 0.3 3.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain CLASP_N PF12348.8 KDO28384.1 - 0.029 13.9 0.1 0.36 10.4 0.0 2.4 1 1 1 2 2 2 0 CLASP N terminal ATP-synt_ab PF00006.25 KDO28384.1 - 0.03 14.0 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 KDO28384.1 - 0.031 13.0 0.0 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KDO28384.1 - 0.043 14.1 0.4 3 8.1 0.0 2.9 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KDO28384.1 - 0.067 13.4 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Vac14_Fab1_bd PF12755.7 KDO28384.1 - 0.092 13.4 0.0 0.76 10.4 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region PRK PF00485.18 KDO28384.1 - 0.12 12.1 0.0 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 KDO28384.1 - 0.12 12.3 0.2 32 4.4 0.2 3.1 3 0 0 3 3 3 0 NTPase FeoB_N PF02421.18 KDO28384.1 - 0.12 11.9 0.1 8.3 5.9 0.0 2.8 3 0 0 3 3 2 0 Ferrous iron transport protein B Septin PF00735.18 KDO28384.1 - 0.15 11.4 0.0 19 4.4 0.0 2.4 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KDO28385.1 - 6e-39 133.7 0.0 3.7e-25 89.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO28385.1 - 2e-11 43.8 1.2 0.00041 19.9 0.1 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO28385.1 - 1.1e-09 38.5 0.4 0.00044 20.2 0.2 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 KDO28385.1 - 3.6e-08 33.2 1.3 8.7e-08 32.0 1.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.6 KDO28385.1 - 0.001 19.2 0.4 0.27 11.5 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KDO28385.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO28385.1 - 0.013 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KDO28385.1 - 0.017 15.3 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KDO28385.1 - 0.021 14.8 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KDO28385.1 - 0.025 14.3 0.2 0.73 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KDO28385.1 - 0.03 14.4 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 KDO28385.1 - 0.043 14.1 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO28385.1 - 0.055 13.2 0.3 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO28385.1 - 0.092 12.9 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 KDO28385.1 - 1.2 9.6 7.9 6.3 7.3 7.9 2.3 1 1 0 1 1 1 0 AAA domain Dicty_REP PF05086.12 KDO28386.1 - 0.082 10.9 0.1 0.1 10.6 0.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPOR PF05036.13 KDO28387.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 2 0 Sporulation related domain BT1 PF03092.16 KDO28388.1 - 2.9e-15 55.5 11.5 1.1e-09 37.2 1.0 3.9 4 0 0 4 4 4 3 BT1 family DUF1325 PF07039.11 KDO28388.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain CrgA PF06781.12 KDO28388.1 - 4.9 7.3 5.4 1.1 9.3 0.4 2.5 2 0 0 2 2 2 0 Cell division protein CrgA BT1 PF03092.16 KDO28389.1 - 3.5e-13 48.7 13.1 7.1e-08 31.1 1.8 3.4 3 0 0 3 3 3 3 BT1 family DUF2953 PF11167.8 KDO28389.1 - 0.53 10.4 3.9 14 5.8 0.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2953) TMEM173 PF15009.6 KDO28389.1 - 2.4 7.3 6.6 5.8 6.0 0.1 3.1 3 0 0 3 3 3 0 Transmembrane protein 173 PH PF00169.29 KDO28390.1 - 6.7e-08 33.0 0.1 1e-07 32.4 0.1 1.3 1 0 0 1 1 1 1 PH domain PH PF00169.29 KDO28391.1 - 1.4e-33 115.6 0.2 4.5e-13 49.6 0.3 3.5 4 0 0 4 4 4 3 PH domain PH_8 PF15409.6 KDO28391.1 - 6.8e-11 42.3 0.0 0.00084 19.6 0.0 3.3 3 0 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KDO28391.1 - 3.7e-08 33.4 0.0 9.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO28391.1 - 5.6e-07 29.9 9.3 0.00014 22.2 2.9 4.6 3 2 0 4 4 4 1 Pleckstrin homology domain PH_9 PF15410.6 KDO28391.1 - 0.00026 21.4 0.7 0.053 13.9 0.1 3.4 4 1 0 4 4 4 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO28391.1 - 0.015 15.4 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Pkinase_Tyr PF07714.17 KDO28392.1 - 1.5e-112 375.1 0.0 1.4e-57 195.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KDO28392.1 - 1.3e-89 300.1 0.0 8.1e-48 163.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KDO28392.1 - 0.0008 19.4 0.8 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO28392.1 - 0.0087 15.4 0.0 0.077 12.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like AP_endonuc_2 PF01261.24 KDO28392.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Haspin_kinase PF12330.8 KDO28392.1 - 0.12 11.2 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain RCC1 PF00415.18 KDO28393.1 - 8e-34 116.0 18.9 4.6e-11 43.2 0.9 7.6 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO28393.1 - 3.3e-25 87.3 25.8 9.7e-08 31.6 0.2 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat BT1 PF03092.16 KDO28394.1 - 3e-33 114.9 17.8 6e-17 61.1 4.0 2.0 2 0 0 2 2 2 2 BT1 family EamA PF00892.20 KDO28394.1 - 0.00087 19.5 2.0 0.00087 19.5 2.0 3.6 3 1 1 4 4 4 1 EamA-like transporter family Peptidase_U4 PF03419.13 KDO28394.1 - 2.9 7.1 18.4 0.13 11.5 3.3 2.9 2 1 1 3 3 3 0 Sporulation factor SpoIIGA Ricin_B_lectin PF00652.22 KDO28396.1 - 2.6e-05 24.5 1.5 3.7e-05 24.0 1.5 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO28396.1 - 0.0019 18.9 0.4 0.004 17.9 0.4 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Bromo_TP PF07524.13 KDO28398.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NSP2-B_epitope PF14757.6 KDO28398.1 - 0.66 9.6 7.1 0.032 13.9 1.1 1.8 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Pkinase PF00069.25 KDO28399.1 - 1.2e-59 201.8 0.0 1.6e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28399.1 - 1.4e-33 116.3 0.0 1.8e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TEP1_N PF05386.11 KDO28399.1 - 0.085 12.5 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 TEP1 N-terminal domain Glutaredoxin PF00462.24 KDO28400.1 - 3.3e-29 100.9 0.0 1.5e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin Pro_isomerase PF00160.21 KDO28400.1 - 8.2e-21 74.9 0.0 1.4e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF836 PF05768.14 KDO28400.1 - 0.0001 22.6 0.0 0.00023 21.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KDO28400.1 - 0.00047 20.6 0.0 0.0045 17.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain GST_N_3 PF13417.6 KDO28400.1 - 0.00051 20.4 0.0 0.0015 18.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain TraF PF13728.6 KDO28400.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KDO28400.1 - 0.015 15.4 0.1 0.28 11.3 0.1 2.5 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.6 KDO28400.1 - 0.092 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin domain Pyr_redox_2 PF07992.14 KDO28401.1 - 2.4e-09 36.8 0.1 7.5e-09 35.2 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KDO28401.1 - 4.3e-06 26.1 0.0 7.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KDO28401.1 - 0.0024 17.2 2.6 0.37 10.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO28401.1 - 0.49 10.4 2.5 39 4.2 3.1 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding PPR_long PF17177.4 KDO28402.1 - 0.018 14.4 0.1 0.14 11.5 0.0 2.3 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP Methyltransf_23 PF13489.6 KDO28402.1 - 0.043 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HEAT_2 PF13646.6 KDO28402.1 - 0.19 12.1 7.1 0.13 12.7 0.3 3.8 4 1 0 4 4 4 0 HEAT repeats TPR_6 PF13174.6 KDO28402.1 - 1 10.1 4.3 5 8.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 KDO28405.1 - 1.9e-12 47.0 0.0 9.9e-12 44.7 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain GST_C_2 PF13410.6 KDO28406.1 - 0.00027 20.9 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO28406.1 - 0.0085 16.5 0.0 0.023 15.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TB2_DP1_HVA22 PF03134.19 KDO28407.1 - 4.4e-21 74.6 2.0 7.3e-21 73.9 2.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family AAA_lid_3 PF17862.1 KDO28407.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain DUF2304 PF10066.9 KDO28407.1 - 0.18 12.0 0.5 0.39 10.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) RAI16-like PF10257.9 KDO28408.1 - 9.8e-37 126.7 0.0 1.7e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PKS_DE PF18369.1 KDO28408.1 - 0.073 13.6 0.1 0.82 10.3 0.3 2.9 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Ndc80_HEC PF03801.13 KDO28409.1 - 1.8e-42 144.5 0.5 6e-42 142.9 0.0 2.2 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 KDO28409.1 - 0.00028 20.9 4.4 0.00028 20.9 4.4 5.3 6 2 1 7 7 7 1 Domain of unknown function (DUF5595) Prominin PF05478.11 KDO28409.1 - 1.9 6.4 23.2 0.33 8.9 8.8 2.6 1 1 1 2 2 2 0 Prominin ubiquitin PF00240.23 KDO28410.1 - 1e-68 227.1 5.1 1.1e-33 114.8 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KDO28410.1 - 5.3e-32 109.5 6.4 1.8e-15 56.5 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO28410.1 - 8.4e-13 48.6 0.9 0.00011 22.5 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KDO28410.1 - 8.9e-08 32.4 0.4 0.016 15.5 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KDO28410.1 - 9.3e-08 31.9 0.2 0.016 15.2 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO28410.1 - 1.3e-07 31.7 0.2 0.029 14.5 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO28410.1 - 7.3e-06 26.5 0.1 0.17 12.4 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KDO28410.1 - 0.00068 19.6 6.5 9 6.4 0.0 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 KDO28410.1 - 0.0019 18.0 0.0 1.8 8.4 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 KDO28410.1 - 0.018 15.4 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Raf1_HTH PF18579.1 KDO28410.1 - 0.054 13.2 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain DUF1940 PF09155.10 KDO28410.1 - 0.097 12.8 0.3 16 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) DUF3861 PF12977.7 KDO28410.1 - 0.099 12.8 0.1 16 5.8 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) CorA PF01544.18 KDO28410.1 - 0.1 11.9 0.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FERM_f0 PF16511.5 KDO28410.1 - 0.14 12.5 2.0 40 4.6 0.2 3.5 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF969 PF06149.12 KDO28410.1 - 0.22 10.9 0.0 7.5 5.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) FlgD_ig PF13860.6 KDO28410.1 - 0.22 11.4 0.6 29 4.6 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain Glyco_hydro_6 PF01341.17 KDO28411.1 - 4.3e-46 158.0 0.0 5.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OLF PF02191.16 KDO28411.1 - 0.24 10.9 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Olfactomedin-like domain C2 PF00168.30 KDO28412.1 - 1e-79 263.4 2.6 6.3e-18 65.0 0.0 7.5 7 0 0 7 7 7 7 C2 domain FerI PF08151.12 KDO28412.1 - 0.00012 22.1 0.0 0.00043 20.3 0.0 2.0 1 0 0 1 1 1 1 FerI (NUC094) domain NT-C2 PF10358.9 KDO28412.1 - 0.00022 21.0 0.4 0.47 10.2 0.1 3.6 3 0 0 3 3 3 2 N-terminal C2 in EEIG1 and EHBP1 proteins PI3K_C2 PF00792.24 KDO28412.1 - 0.016 15.1 0.0 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Cwf_Cwc_15 PF04889.12 KDO28412.1 - 2.1 8.0 13.9 0.029 14.1 4.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_1 PF00561.20 KDO28415.1 - 8.3e-34 117.4 0.0 1e-33 117.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO28415.1 - 2.4e-06 28.3 3.3 3.6e-06 27.7 3.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KDO28415.1 - 0.054 13.6 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein Sulfate_transp PF00916.20 KDO28416.1 - 2.3e-11 43.1 17.0 7.2e-11 41.4 17.0 1.8 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KDO28416.1 - 0.031 13.9 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 STAS domain Yip1 PF04893.17 KDO28418.1 - 0.0014 18.4 13.8 0.0015 18.3 13.0 1.4 1 1 0 1 1 1 1 Yip1 domain DUF3522 PF12036.8 KDO28418.1 - 0.013 15.8 2.9 0.013 15.8 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) Ion_trans PF00520.31 KDO28419.1 - 0.00022 20.5 5.3 0.00031 20.1 5.3 1.2 1 0 0 1 1 1 1 Ion transport protein COX14 PF14880.6 KDO28419.1 - 0.57 10.1 3.7 1.1 9.2 1.5 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DcpS_C PF11969.8 KDO28420.1 - 9.6e-22 77.6 0.5 1.7e-21 76.8 0.5 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 KDO28420.1 - 3.4e-13 49.8 0.9 6.4e-13 48.9 0.9 1.4 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KDO28420.1 - 5.3e-12 46.3 3.4 6.4e-12 46.1 1.8 1.9 2 1 0 2 2 2 1 HIT domain zf-C2H2 PF00096.26 KDO28420.1 - 0.024 15.1 2.3 0.024 15.1 2.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KDO28420.1 - 0.067 13.5 1.4 0.094 13.1 0.4 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KDO28420.1 - 0.5 11.4 6.2 0.32 11.9 2.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DAO PF01266.24 KDO28421.1 - 1.8e-55 188.9 0.1 2.6e-55 188.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KDO28421.1 - 1e-35 122.4 0.2 1.8e-35 121.6 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KDO28421.1 - 1.6e-07 30.8 4.8 3e-06 26.6 4.8 2.3 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KDO28421.1 - 9.5e-07 28.5 1.3 4.2e-06 26.4 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KDO28421.1 - 2.4e-05 23.6 3.2 0.00098 18.3 1.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KDO28421.1 - 6.4e-05 22.3 3.3 0.00041 19.7 3.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO28421.1 - 7.3e-05 21.6 1.1 7.3e-05 21.6 1.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KDO28421.1 - 0.00025 20.4 0.2 0.41 9.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KDO28421.1 - 0.0004 20.6 0.4 0.0024 18.1 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KDO28421.1 - 0.0018 17.6 0.2 0.005 16.1 0.2 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KDO28421.1 - 0.0046 16.3 0.9 0.053 12.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO28421.1 - 0.013 16.1 8.7 0.042 14.4 0.6 3.9 5 0 0 5 5 4 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KDO28421.1 - 0.023 14.6 0.1 0.054 13.4 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4197 PF13852.6 KDO28421.1 - 0.059 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) K_oxygenase PF13434.6 KDO28421.1 - 0.13 11.4 0.4 20 4.2 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF433 PF04255.14 KDO28421.1 - 0.15 11.9 0.2 30 4.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Lycopene_cycl PF05834.12 KDO28421.1 - 0.29 10.1 2.1 2.5 7.0 0.9 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Msg2_C PF12373.8 KDO28421.1 - 2.8 7.4 5.9 1.6 8.2 0.5 2.9 3 0 0 3 3 3 0 Major surface glycoprotein 2 C terminal SAM_2 PF07647.17 KDO28422.1 - 3.9e-09 36.5 0.0 9.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO28422.1 - 1.2e-07 32.1 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3 PF00041.21 KDO28422.1 - 1.9e-07 31.3 0.2 5.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain EF-hand_1 PF00036.32 KDO28422.1 - 7.5e-07 28.3 0.7 0.036 13.6 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KDO28422.1 - 1.6e-05 24.5 0.5 0.13 12.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KDO28422.1 - 1.7e-05 24.1 1.7 0.02 14.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO28422.1 - 5.2e-05 23.6 2.5 0.095 13.2 0.0 3.2 1 1 2 3 3 3 2 EF-hand domain pair fn3_4 PF16794.5 KDO28422.1 - 0.0039 17.1 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Fibronectin-III type domain zf-AN1 PF01428.16 KDO28422.1 - 0.0053 16.9 5.7 0.015 15.5 5.7 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger SPARC_Ca_bdg PF10591.9 KDO28422.1 - 0.017 15.4 0.5 0.9 9.9 0.1 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GTP_EFTU PF00009.27 KDO28424.1 - 1.9e-05 24.3 0.2 3e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO28424.1 - 0.0054 16.8 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KDO28424.1 - 0.035 13.1 0.1 0.078 11.9 0.1 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 KDO28424.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 KDO28424.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DHC_N2 PF08393.13 KDO28426.1 - 1.9e-55 188.6 1.4 4e-55 187.6 1.4 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KDO28426.1 - 8.2e-25 87.5 0.0 1.7e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 KDO28426.1 - 8.9e-23 80.7 0.2 2e-14 53.5 0.0 5.2 4 1 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 KDO28426.1 - 1.5e-13 50.7 0.0 1.1e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 KDO28426.1 - 2.5e-08 34.1 0.0 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KDO28426.1 - 6.7e-06 26.6 0.3 0.011 16.2 0.0 4.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO28426.1 - 0.00011 22.5 2.5 2.5 8.4 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.6 KDO28426.1 - 0.00023 20.8 1.3 0.28 11.0 0.0 4.0 4 0 0 4 4 4 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KDO28426.1 - 0.00028 20.6 0.0 3.6 7.3 0.0 4.2 4 0 0 4 4 4 1 Sigma-54 interaction domain Rad17 PF03215.15 KDO28426.1 - 0.00032 20.7 0.0 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Rad17 P-loop domain DUF815 PF05673.13 KDO28426.1 - 0.00051 19.3 0.7 3.9 6.6 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 KDO28426.1 - 0.0025 17.8 0.2 22 5.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KDO28426.1 - 0.0051 16.7 0.0 2.1 8.2 0.0 3.8 4 0 0 4 4 4 1 RsgA GTPase AAA_30 PF13604.6 KDO28426.1 - 0.0071 16.1 1.6 0.16 11.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KDO28426.1 - 0.0099 15.5 0.2 5.6 6.5 0.0 4.0 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KDO28426.1 - 0.02 15.4 0.0 5.3 7.6 0.0 3.2 3 0 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 KDO28426.1 - 0.055 12.8 0.3 13 5.1 0.1 3.6 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KDO28426.1 - 0.092 13.3 0.2 3.3 8.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.6 KDO28426.1 - 0.096 13.1 19.8 1.6 9.0 0.3 6.9 7 2 1 8 8 6 0 AAA ATPase domain AAA_23 PF13476.6 KDO28426.1 - 0.16 12.5 0.0 0.52 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain MT PF12777.7 KDO28427.1 - 2.9e-28 98.9 1.0 4.4e-28 98.3 1.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 KDO28427.1 - 4.8e-12 45.7 0.5 1.8e-11 43.8 0.0 2.2 2 1 0 2 2 2 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 KDO28427.1 - 3.8e-05 23.8 0.1 0.00025 21.1 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain HAUS-augmin3 PF14932.6 KDO28427.1 - 0.022 14.4 4.9 0.051 13.1 4.9 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_9 PF12781.7 KDO28427.1 - 0.022 13.9 0.0 0.68 9.0 0.0 2.8 2 1 0 2 2 2 0 ATP-binding dynein motor region Fib_alpha PF08702.10 KDO28427.1 - 0.93 9.7 11.7 5.6 7.2 0.6 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 KDO28427.1 - 1.8 6.7 7.2 8.2 4.5 0.1 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA zf-RING_2 PF13639.6 KDO28428.1 - 0.011 16.1 3.5 0.026 14.8 3.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KDO28428.1 - 0.025 14.6 2.2 0.052 13.5 2.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain ANAPC4_WD40 PF12894.7 KDO28428.1 - 0.098 13.0 0.0 4.2 7.7 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_11 PF17123.5 KDO28428.1 - 0.12 12.1 0.4 0.33 10.7 0.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KDO28428.1 - 0.17 12.2 2.2 0.38 11.1 2.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40 PF00400.32 KDO28428.1 - 0.83 10.6 2.5 1e+02 4.0 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat TPR_14 PF13428.6 KDO28428.1 - 4.1 8.5 5.4 1.9 9.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.25 KDO28429.1 - 6.5e-42 143.2 0.0 8.1e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO28429.1 - 6.6e-23 81.5 0.2 1.2e-22 80.7 0.1 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO28429.1 - 4.6e-09 36.4 0.2 7.5e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO28429.1 - 0.00079 19.0 0.3 0.0025 17.3 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO28429.1 - 0.0059 16.5 0.3 0.0087 16.0 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KDO28429.1 - 0.012 16.1 0.3 0.023 15.3 0.3 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KDO28429.1 - 0.025 14.8 0.2 0.081 13.2 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain PP2C PF00481.21 KDO28430.1 - 1.4e-43 149.4 0.0 2.2e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C UQ_con PF00179.26 KDO28430.1 - 0.00016 21.4 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP2C_2 PF13672.6 KDO28430.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3248 PF11609.8 KDO28430.1 - 0.094 12.6 0.0 21 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) REJ PF02010.15 KDO28431.1 - 2.9e-39 135.1 8.0 1.4e-37 129.6 0.3 2.8 2 1 1 3 3 3 2 REJ domain GPS PF01825.21 KDO28431.1 - 1.2e-08 35.3 3.6 3.5e-08 33.8 3.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif CopC PF04234.12 KDO28431.1 - 0.039 15.0 0.1 0.3 12.2 0.0 2.6 2 0 0 2 2 2 0 CopC domain UQ_con PF00179.26 KDO28432.1 - 1.1e-25 89.9 0.0 1.4e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Gtr1_RagA PF04670.12 KDO28433.1 - 1e-68 231.2 0.8 1.2e-68 230.9 0.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KDO28433.1 - 0.00012 21.6 0.0 0.00048 19.6 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KDO28433.1 - 0.00015 21.2 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO28433.1 - 0.00037 20.5 0.0 0.00074 19.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KDO28433.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KDO28433.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KDO28433.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.25 KDO28434.1 - 5.3e-35 120.9 12.4 8.2e-35 120.3 12.4 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KDO28434.1 - 5.4e-14 51.9 0.8 1.5e-13 50.5 0.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KDO28434.1 - 0.0034 17.7 4.5 0.0034 17.7 4.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein PAH PF02671.21 KDO28434.1 - 1.7 8.9 4.1 3.8 7.7 3.5 2.1 1 1 0 1 1 1 0 Paired amphipathic helix repeat AMP-binding_C_2 PF14535.6 KDO28434.1 - 4.4 7.7 6.8 11 6.4 0.6 3.1 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain MMR_HSR1_Xtn PF16897.5 KDO28437.1 - 3e-41 139.7 0.8 5.7e-41 138.8 0.8 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KDO28437.1 - 4.6e-20 71.8 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KDO28437.1 - 1.1e-18 67.1 0.0 2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KDO28437.1 - 3.5e-10 39.6 0.1 1.7e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KDO28437.1 - 0.00053 19.0 0.2 0.0041 16.1 0.2 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KDO28437.1 - 0.0013 18.8 1.1 0.32 11.0 0.0 2.7 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KDO28437.1 - 0.083 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 KDO28437.1 - 0.089 12.3 1.4 1.5 8.4 0.1 3.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AA_permease PF00324.21 KDO28438.1 - 1.7e-20 73.1 33.8 2.4e-20 72.6 33.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO28438.1 - 1.4e-16 60.3 40.7 1.8e-16 60.0 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease ArgJ PF01960.18 KDO28439.1 - 4.4e-110 367.9 0.0 5.4e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family MSC PF09402.10 KDO28440.1 - 0.00026 20.6 0.1 0.00048 19.7 0.1 1.6 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF4211 PF13926.6 KDO28441.1 - 2.4e-18 66.5 0.6 6.4e-18 65.2 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) zf-C3HC4_3 PF13920.6 KDO28441.1 - 7e-08 32.2 6.4 7e-08 32.2 6.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KDO28441.1 - 0.75 9.9 7.5 1.4 9.0 4.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1713 PF08213.11 KDO28442.1 - 1.1e-08 34.8 17.8 1.8e-08 34.2 17.8 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Podoplanin PF05808.11 KDO28443.1 - 5.8e-05 23.2 1.7 7.9e-05 22.8 1.7 1.2 1 0 0 1 1 1 1 Podoplanin Gram_pos_anchor PF00746.21 KDO28443.1 - 0.049 13.6 0.7 0.049 13.6 0.7 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif S1FA PF04689.13 KDO28443.1 - 0.2 11.8 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA PhrC_PhrF PF11131.8 KDO28443.1 - 0.58 9.8 5.7 25 4.6 0.5 3.4 2 1 1 3 3 3 0 Rap-phr extracellular signalling SOG2 PF10428.9 KDO28443.1 - 1.3 8.1 6.6 1.7 7.8 6.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cupredoxin_1 PF13473.6 KDO28444.1 - 0.041 14.0 0.0 0.74 10.0 0.0 2.4 2 1 0 2 2 2 0 Cupredoxin-like domain Pkinase_Tyr PF07714.17 KDO28445.1 - 3.1e-28 98.8 0.0 5.6e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28445.1 - 2.2e-27 96.1 0.0 4.3e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 KDO28445.1 - 6e-15 55.4 0.0 1.6e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 C2 domain Kdo PF06293.14 KDO28445.1 - 0.00049 19.5 0.1 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rootletin PF15035.6 KDO28445.1 - 0.0012 18.9 1.5 0.0022 18.0 1.5 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CALCOCO1 PF07888.11 KDO28445.1 - 0.006 15.5 3.3 0.0093 14.9 3.3 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Kinase-like PF14531.6 KDO28445.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ABC_tran_CTD PF16326.5 KDO28445.1 - 0.42 10.9 2.6 1.9 8.8 2.6 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 KDO28445.1 - 1.5 9.1 4.3 1.3 9.3 1.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 KDO28446.1 - 1.5e-32 113.0 0.0 2.2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28446.1 - 3.4e-30 105.2 0.0 5.5e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KDO28446.1 - 8.1e-09 35.7 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kdo PF06293.14 KDO28446.1 - 8.6e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO28446.1 - 0.0056 16.0 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO28446.1 - 0.039 13.9 5.6 0.28 11.1 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO28446.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DZR PF12773.7 KDO28446.1 - 0.21 11.7 1.3 0.41 10.7 1.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KDO28446.1 - 0.27 10.7 2.7 0.48 9.9 2.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KDO28446.1 - 0.49 10.2 3.2 0.89 9.4 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase_Tyr PF07714.17 KDO28447.1 - 1.7e-19 70.2 0.0 2.9e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28447.1 - 7.8e-16 58.2 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 KDO28447.1 - 7.8e-05 22.9 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain CASP_C PF08172.12 KDO28447.1 - 0.0018 17.7 0.6 0.0029 17.0 0.6 1.2 1 0 0 1 1 1 1 CASP C terminal CENP-H PF05837.12 KDO28447.1 - 0.0029 18.0 4.5 0.0081 16.6 4.5 1.7 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Kinase-like PF14531.6 KDO28447.1 - 0.0035 16.7 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TMF_TATA_bd PF12325.8 KDO28447.1 - 0.0043 17.3 4.5 0.011 16.0 4.5 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Mei5 PF10376.9 KDO28447.1 - 0.0072 16.2 1.8 0.013 15.4 1.8 1.3 1 0 0 1 1 1 1 Double-strand recombination repair protein Myosin_tail_1 PF01576.19 KDO28447.1 - 0.023 12.5 2.7 0.032 12.0 2.7 1.1 1 0 0 1 1 1 0 Myosin tail APG6_N PF17675.1 KDO28447.1 - 0.09 13.3 7.6 0.26 11.8 7.6 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KDO28447.1 - 0.1 13.0 0.9 21 5.6 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Myc-LZ PF02344.15 KDO28447.1 - 0.18 11.9 4.8 0.16 12.1 2.0 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain YabA PF06156.13 KDO28447.1 - 0.19 12.4 1.9 0.63 10.7 1.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 KDO28447.1 - 0.59 9.7 7.6 3.7 7.1 0.9 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 KDO28447.1 - 0.93 9.8 4.3 1.9 8.8 4.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.18 KDO28447.1 - 0.95 9.7 8.6 0.11 12.7 2.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.6 KDO28447.1 - 1.1 9.7 8.3 1.8 9.1 0.8 2.6 1 1 1 2 2 2 0 Snapin/Pallidin FlxA PF14282.6 KDO28447.1 - 1.2 9.2 5.8 2.5 8.1 5.8 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.6 KDO28447.1 - 2.1 8.8 7.3 7.7 7.0 0.7 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 KDO28447.1 - 4.5 7.7 6.1 6.6 7.2 0.2 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_23 PF13476.6 KDO28447.1 - 7 7.1 6.6 11 6.5 6.6 1.2 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 KDO28447.1 - 7.9 6.3 8.0 8.5 6.2 1.6 2.6 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 KDO28447.1 - 8.9 6.8 10.0 21 5.6 8.5 2.4 2 1 0 2 2 2 0 Cell division protein ZapB Pkinase_Tyr PF07714.17 KDO28448.1 - 1.4e-21 77.0 0.0 3.6e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28448.1 - 7.9e-20 71.3 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 KDO28448.1 - 0.00062 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain CheZ PF04344.13 KDO28448.1 - 0.015 15.2 2.9 0.027 14.4 2.3 1.6 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ OmpH PF03938.14 KDO28448.1 - 0.13 12.6 9.4 0.27 11.6 9.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 KDO28448.1 - 0.34 11.2 4.1 1.1 9.6 4.1 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain DZR PF12773.7 KDO28448.1 - 0.61 10.2 3.8 1.2 9.2 3.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S3Ae PF01015.18 KDO28449.1 - 3.7e-90 300.9 3.0 4.4e-90 300.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family FHA PF00498.26 KDO28450.1 - 5.8e-08 33.0 0.0 8.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO28450.1 - 0.026 14.8 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KDO28450.1 - 0.031 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 FHA domain AP_endonuc_2 PF01261.24 KDO28451.1 - 1e-06 28.4 1.0 1.7e-06 27.7 1.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel APOC4 PF15119.6 KDO28453.1 - 0.15 12.3 0.2 3.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Apolipoprotein C4 DUF829 PF05705.14 KDO28455.1 - 5.3e-32 111.6 0.0 6e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF829 PF05705.14 KDO28456.1 - 4.1e-17 62.9 0.0 5.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) SANT_DAMP1_like PF16282.5 KDO28457.1 - 0.0059 16.8 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 MurJ PF03023.14 KDO28457.1 - 0.09 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Lipid II flippase MurJ DUF829 PF05705.14 KDO28458.1 - 3.6e-26 92.5 0.0 5.8e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Sterol_MT_C PF08498.10 KDO28458.1 - 1.9e-11 44.1 0.2 5.6e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal DUF829 PF05705.14 KDO28459.1 - 2.7e-07 30.8 0.0 2.7e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Chorein_N PF12624.7 KDO28461.1 - 3.6e-22 78.7 0.3 2.6e-21 75.9 0.1 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 MMR_HSR1 PF01926.23 KDO28461.1 - 1.7e-18 66.8 0.2 6.4e-14 52.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO28461.1 - 2.2e-08 33.8 0.2 3.7e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B ATG2_CAD PF13329.6 KDO28461.1 - 1.7e-07 31.1 0.0 6e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif RsgA_GTPase PF03193.16 KDO28461.1 - 4.1e-06 26.8 0.7 0.094 12.6 0.1 2.7 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO28461.1 - 1.2e-05 25.0 0.3 0.0003 20.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain VPS13 PF16908.5 KDO28461.1 - 8.4e-05 22.5 0.0 0.0003 20.7 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KDO28461.1 - 0.00018 21.3 0.0 0.00068 19.5 0.0 2.0 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal AIG1 PF04548.16 KDO28461.1 - 0.00078 18.8 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KDO28461.1 - 0.022 14.8 4.9 0.7 9.9 0.6 3.0 2 2 1 3 3 3 0 Dynamin family DUF815 PF05673.13 KDO28461.1 - 0.061 12.5 0.3 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KDO28461.1 - 0.081 13.3 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain CDC45 PF02724.14 KDO28461.1 - 3.4 5.8 10.6 2.2 6.5 0.1 2.1 2 0 0 2 2 2 0 CDC45-like protein ANAPC4_WD40 PF12894.7 KDO28462.1 - 3.6e-06 27.2 0.0 1.9 8.8 0.0 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO28462.1 - 0.003 18.3 3.9 1.1 10.3 0.1 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 KDO28462.1 - 0.03 14.3 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 KDO28462.1 - 0.043 12.1 0.0 0.8 7.9 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Hist_deacetyl PF00850.19 KDO28463.1 - 7.5e-81 271.9 0.2 9.7e-81 271.6 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.32 KDO28464.1 - 7.4e-18 64.6 15.2 6.8e-06 26.7 0.2 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28464.1 - 0.0043 17.3 0.1 5.4 7.4 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.21 KDO28464.1 - 0.01 15.8 0.1 3.5 7.9 0.0 4.1 3 0 0 3 3 3 0 NHL repeat PQQ_3 PF13570.6 KDO28464.1 - 0.013 16.0 11.4 1.3 9.6 0.5 5.0 6 1 0 6 6 6 0 PQQ-like domain Nup160 PF11715.8 KDO28464.1 - 0.083 11.5 0.0 0.93 8.1 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KDO28464.1 - 0.13 11.8 0.6 1.6 8.3 0.0 2.7 2 1 2 4 4 4 0 PQQ-like domain Zn_Tnp_IS1 PF03811.13 KDO28464.1 - 0.19 11.5 1.1 2.7 7.8 0.1 2.5 2 0 0 2 2 2 0 InsA N-terminal domain PQQ PF01011.21 KDO28464.1 - 0.48 10.4 2.6 33 4.6 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat RRM_1 PF00076.22 KDO28466.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 KDO28466.1 - 0.042 13.8 6.5 0.05 13.6 6.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Oxysterol_BP PF01237.18 KDO28466.1 - 0.062 12.1 0.4 0.087 11.6 0.4 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein HHH_2 PF12826.7 KDO28466.1 - 0.14 12.3 0.3 0.35 11.0 0.3 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Nucleo_P87 PF07267.11 KDO28466.1 - 7.7 5.2 7.1 10 4.8 7.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pannexin_like PF12534.8 KDO28466.1 - 9.2 5.2 7.0 7.8 5.5 4.9 1.7 1 1 1 2 2 2 0 Pannexin-like TM region of LRRC8 Hist_deacetyl PF00850.19 KDO28468.1 - 2.9e-81 273.3 0.0 4.3e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.6 KDO28470.1 - 7.9e-24 83.7 3.5 4.3e-09 36.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28470.1 - 2e-22 79.6 6.9 8.5e-09 35.9 0.6 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO28470.1 - 3.3e-15 54.7 7.4 0.23 12.1 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KDO28470.1 - 5.5e-12 45.7 12.2 0.00041 20.6 0.2 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO28470.1 - 3.1e-11 43.2 17.5 0.061 13.8 0.1 6.7 3 2 2 5 5 5 4 Ankyrin repeat DUF2870 PF11069.8 KDO28471.1 - 1.1e-27 96.2 4.7 2.8e-25 88.5 4.7 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2870) Taeniidae_ag PF05596.11 KDO28471.1 - 0.0048 16.9 0.0 0.73 9.9 0.0 2.9 2 1 0 2 2 2 2 Taeniidae antigen Ion_trans PF00520.31 KDO28472.1 - 0.0016 17.7 13.5 0.0016 17.7 13.5 2.1 2 0 0 2 2 2 1 Ion transport protein Cep57_MT_bd PF06657.13 KDO28472.1 - 0.094 13.2 0.9 24 5.5 0.0 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CDP-OH_P_transf PF01066.21 KDO28473.1 - 5.9e-12 46.2 0.6 5.9e-12 46.2 0.6 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase LRR_4 PF12799.7 KDO28474.1 - 0.00027 21.3 1.5 0.18 12.3 0.0 4.9 2 2 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO28474.1 - 0.0025 17.5 1.8 12 5.7 0.1 4.3 4 2 0 4 4 4 2 Leucine rich repeat CDtoxinA PF03498.14 KDO28474.1 - 1.2 8.7 4.0 31 4.1 0.1 3.6 3 1 1 4 4 4 0 Cytolethal distending toxin A/C domain Metallophos PF00149.28 KDO28476.1 - 8.8e-30 104.7 0.5 1.7e-29 103.8 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FYVE PF01363.21 KDO28476.1 - 1.8e-12 47.2 10.3 1.8e-12 47.2 10.3 2.5 3 0 0 3 3 3 1 FYVE zinc finger EF-hand_8 PF13833.6 KDO28476.1 - 4.1e-07 29.7 3.8 0.0013 18.5 0.8 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 KDO28476.1 - 6.3e-06 26.6 3.8 0.00014 22.2 0.9 3.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO28476.1 - 0.00051 19.4 3.1 0.54 9.9 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KDO28476.1 - 0.0028 17.5 7.1 0.065 13.2 0.4 4.4 5 0 0 5 5 5 1 EF-hand domain PH_8 PF15409.6 KDO28476.1 - 0.043 14.1 0.2 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain T2SSJ PF11612.8 KDO28476.1 - 0.19 12.0 0.4 0.53 10.5 0.4 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J PX PF00787.24 KDO28477.1 - 8.7e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 PX domain LRR_8 PF13855.6 KDO28478.1 - 4.6e-08 32.7 1.4 1.2e-07 31.3 1.3 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO28478.1 - 1.9e-06 28.1 0.8 1.5e-05 25.2 0.2 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO28478.1 - 6.8e-06 26.4 10.9 6.8e-06 26.4 10.9 2.0 2 0 0 2 2 2 1 LNR domain DUF1418 PF07214.12 KDO28478.1 - 0.77 9.7 7.0 3 7.7 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) ADH_N PF08240.12 KDO28479.1 - 1.8e-23 82.5 7.1 3.4e-23 81.6 7.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KDO28479.1 - 6.3e-19 68.3 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO28479.1 - 1e-10 42.8 0.0 1.5e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KDO28479.1 - 0.00027 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KDO28479.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_A22B PF04258.13 KDO28480.1 - 1.6e-48 165.7 11.5 1.6e-48 165.7 11.5 2.5 2 1 0 2 2 2 1 Signal peptide peptidase PA PF02225.22 KDO28480.1 - 1.1e-06 28.6 0.1 6.9e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 PA domain HSP70 PF00012.20 KDO28481.1 - 1.8e-102 343.5 0.0 2.9e-102 342.8 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO28481.1 - 3.9e-11 42.4 0.1 1.4e-05 24.1 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FGGY_C PF02782.16 KDO28481.1 - 0.00013 21.8 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Herpes_gE PF02480.16 KDO28482.1 - 0.0048 15.7 1.1 0.013 14.3 0.1 2.1 2 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E stn_TNFRSF12A PF12191.8 KDO28482.1 - 0.0084 16.3 0.2 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Chordopox_A13L PF05961.11 KDO28482.1 - 0.088 13.1 0.1 1.9 8.8 0.0 2.6 2 1 1 3 3 3 0 Chordopoxvirus A13L protein DUF1180 PF06679.12 KDO28482.1 - 2.6 8.4 6.1 6.2 7.2 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5009 PF16401.5 KDO28483.1 - 2.8e-06 27.0 3.2 9.2e-06 25.3 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5009) DUF1624 PF07786.12 KDO28483.1 - 0.0018 17.9 9.2 0.0041 16.7 9.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) DUF2165 PF09933.9 KDO28483.1 - 0.0049 16.9 1.6 0.0049 16.9 1.6 2.1 3 0 0 3 3 3 1 Predicted small integral membrane protein (DUF2165) DUF4293 PF14126.6 KDO28483.1 - 0.094 13.0 3.7 9 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Myb_DNA-binding PF00249.31 KDO28484.1 - 1.3e-10 41.2 0.5 1.9e-10 40.7 0.1 1.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO28484.1 - 9.9e-05 22.5 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO28485.1 - 5.6e-11 42.5 0.1 8.7e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO28485.1 - 0.0013 18.9 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HRDC PF00570.23 KDO28485.1 - 0.1 12.6 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 HRDC domain Myb_DNA-binding PF00249.31 KDO28486.1 - 3.9e-11 42.9 0.3 6e-11 42.4 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO28486.1 - 0.0018 18.5 0.4 0.0033 17.6 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO28487.1 - 1.1e-12 47.9 0.2 1.5e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO28487.1 - 0.0024 18.1 0.2 0.0034 17.6 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dicty_REP PF05086.12 KDO28488.1 - 0.56 8.1 3.3 0.83 7.5 3.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 KDO28488.1 - 0.89 7.7 3.0 1.4 7.0 3.0 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 OHCU_decarbox PF09349.10 KDO28489.1 - 7.4e-29 101.2 0.4 6e-28 98.3 0.4 1.9 1 1 0 1 1 1 1 OHCU decarboxylase ECH_1 PF00378.20 KDO28490.1 - 1.4e-86 289.9 1.5 1.6e-86 289.7 1.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO28490.1 - 6.7e-39 134.3 1.5 3.6e-35 122.0 0.7 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EphA2_TM PF14575.6 KDO28491.1 - 0.17 12.8 0.5 4.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 KDO28491.1 - 0.87 9.9 4.0 1 9.7 0.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) EF-hand_1 PF00036.32 KDO28494.1 - 1.2e-17 62.1 5.2 6e-05 22.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO28494.1 - 5.7e-17 60.1 2.7 6.6e-05 22.5 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KDO28494.1 - 8e-17 59.9 0.4 9.6e-05 21.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KDO28494.1 - 3.3e-16 59.5 3.5 4e-10 40.0 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KDO28494.1 - 1.2e-12 47.5 2.9 7.6e-07 28.9 0.0 3.3 3 2 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO28494.1 - 0.0012 19.1 0.0 0.014 15.7 0.0 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO28494.1 - 0.022 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_11 PF08976.11 KDO28494.1 - 0.11 13.4 0.0 5 8.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Nup88 PF10168.9 KDO28495.1 - 0.065 11.0 0.0 0.077 10.8 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF1664 PF07889.12 KDO28495.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_12 PF13087.6 KDO28496.1 - 5e-56 189.5 0.0 1.3e-55 188.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KDO28496.1 - 5.7e-55 186.9 5.7 2.1e-32 112.9 1.1 4.0 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.6 KDO28496.1 - 1.5e-09 38.3 0.7 4.3e-09 36.9 0.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO28496.1 - 3e-09 36.9 2.4 5.4e-08 32.8 2.4 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KDO28496.1 - 0.00032 20.5 0.2 3.4 7.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KDO28496.1 - 0.00035 20.2 1.5 0.04 13.4 0.2 2.6 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KDO28496.1 - 0.0095 16.0 0.0 0.09 12.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KDO28496.1 - 0.036 13.5 0.3 0.31 10.5 0.2 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 KDO28496.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.7 3 0 0 3 3 3 0 AAA ATPase domain BSP_II PF05432.11 KDO28496.1 - 2.3 7.8 28.4 0.78 9.4 5.9 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TPR_2 PF07719.17 KDO28497.1 - 2.3e-12 46.0 11.7 6.9e-06 25.8 0.6 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO28497.1 - 3.1e-10 39.7 3.5 0.0062 16.8 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28497.1 - 8e-10 38.7 9.9 0.01 16.6 0.1 5.3 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO28497.1 - 8.7e-08 32.7 1.6 3.5e-05 24.3 0.2 3.8 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO28497.1 - 1.1e-07 31.5 3.2 6e-05 22.9 0.3 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO28497.1 - 1.8e-07 31.5 10.0 0.00033 21.1 1.3 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO28497.1 - 9.2e-07 28.4 4.7 0.0089 15.8 0.6 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO28497.1 - 1.2e-06 28.7 5.1 0.18 12.1 0.0 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28497.1 - 5.7e-06 26.0 3.8 0.21 11.7 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO28497.1 - 9.5e-06 25.2 6.0 0.012 15.3 0.0 3.8 3 1 1 4 4 4 2 TPR repeat DUF5588 PF17826.1 KDO28497.1 - 0.00019 20.5 0.2 0.0006 18.8 0.2 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5588) TPR_9 PF13371.6 KDO28497.1 - 0.00027 21.0 1.6 0.007 16.5 0.2 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO28497.1 - 0.0018 18.8 7.9 0.37 11.5 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 KDO28497.1 - 0.0036 16.3 0.1 0.18 10.6 0.0 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TOM20_plant PF06552.12 KDO28497.1 - 0.086 12.6 0.1 15 5.3 0.0 3.1 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 La_HTH_kDCL PF18177.1 KDO28497.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.7 2 0 0 2 2 1 0 La HTH in kinetoplastid DICER domain Aconitase PF00330.20 KDO28498.1 - 1.9e-65 221.6 0.4 2e-63 215.0 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KDO28498.1 - 1.6e-17 64.0 0.0 3.9e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain Bystin PF05291.11 KDO28499.1 - 1.7e-125 418.1 0.0 2.1e-125 417.9 0.0 1.1 1 0 0 1 1 1 1 Bystin Elicitin PF00964.17 KDO28501.1 - 0.0029 17.7 1.7 0.0037 17.3 1.7 1.2 1 0 0 1 1 1 1 Elicitin PEPCK_GTP PF00821.18 KDO28502.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Peptidase_C1 PF00112.23 KDO28503.1 - 0.084 13.0 0.0 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Papain family cysteine protease adh_short_C2 PF13561.6 KDO28504.1 - 3.6e-60 203.4 0.3 4.1e-60 203.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO28504.1 - 2.6e-49 167.3 0.2 3.1e-49 167.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO28504.1 - 2.4e-11 43.9 0.2 3.3e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO28504.1 - 0.0011 18.4 0.6 0.0049 16.4 0.3 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KDO28504.1 - 0.038 13.4 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KDO28504.1 - 0.067 12.5 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flavodoxin_1 PF00258.25 KDO28504.1 - 0.15 12.2 0.0 0.73 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin 5_nucleotid PF05761.14 KDO28505.1 - 1.2e-132 443.1 3.0 1.4e-132 442.9 3.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KDO28505.1 - 0.044 13.9 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Glucan_synthase PF02364.15 KDO28506.1 - 3e-189 631.0 4.7 3e-165 551.7 1.0 2.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO28506.1 - 3.5e-20 72.7 0.1 3.6e-18 66.2 0.1 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RFC1 PF08519.12 KDO28506.1 - 0.017 15.3 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Sec7_N PF12783.7 KDO28506.1 - 0.064 13.1 0.6 0.21 11.5 0.6 1.9 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Catalase_C PF18011.1 KDO28508.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 C-terminal domain found in long catalases CRM1_C PF08767.11 KDO28513.1 - 8.1e-06 25.2 0.1 1.9e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 CRM1 C terminal DMRT-like PF15791.5 KDO28513.1 - 0.0077 16.6 4.1 1.9 8.9 0.1 2.6 2 0 0 2 2 2 2 Doublesex-and mab-3-related transcription factor C1 and C2 PAP_central PF04928.17 KDO28514.1 - 4.4e-95 317.4 0.0 5.5e-95 317.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KDO28514.1 - 4.6e-17 62.2 0.0 1.3e-09 37.9 0.0 2.3 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KDO28514.1 - 1.3e-08 35.0 0.0 9.3e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KDO28514.1 - 0.19 11.5 0.4 0.44 10.3 0.1 1.7 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain Ribosomal_L12 PF00542.19 KDO28515.1 - 4e-23 81.5 9.0 1.2e-22 80.0 9.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KDO28515.1 - 4e-07 29.6 2.4 2.3e-05 24.0 0.2 2.6 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain HTH_13 PF11972.8 KDO28515.1 - 0.11 12.5 0.1 0.37 10.9 0.1 1.9 2 0 0 2 2 2 0 HTH DNA binding domain Ndufs5 PF10200.9 KDO28516.1 - 6.6e-05 23.1 0.0 8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KDO28516.1 - 0.037 14.4 1.0 0.07 13.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) WD40 PF00400.32 KDO28517.1 - 1.1e-06 29.2 0.1 3.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO28517.1 - 0.0013 17.8 0.0 0.0014 17.7 0.0 1.0 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein START PF01852.19 KDO28519.1 - 5.8e-05 22.6 0.0 8.2e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO28519.1 - 0.0032 17.7 7.6 0.0052 17.0 7.6 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO28519.1 - 0.026 14.7 19.0 0.052 13.7 19.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 KDO28520.1 - 3e-10 40.1 14.3 5.8e-10 39.2 14.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO28520.1 - 9.8e-05 22.6 5.8 0.0002 21.6 5.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_5 PF14634.6 KDO28520.1 - 6.9 6.7 15.7 4.6 7.3 13.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain FYVE PF01363.21 KDO28521.1 - 1.5e-06 28.3 13.4 3.5e-06 27.0 13.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO28521.1 - 3.3e-06 27.3 6.1 7.2e-06 26.2 6.1 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 KDO28521.1 - 0.2 11.9 13.3 0.11 12.7 10.0 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-HIT PF04438.16 KDO28521.1 - 1.3 9.0 10.9 4.5 7.2 10.9 2.0 1 0 0 1 1 1 0 HIT zinc finger FYVE PF01363.21 KDO28522.1 - 2.7e-07 30.6 15.4 5.1e-07 29.7 15.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO28522.1 - 2.6e-05 23.7 7.2 0.0008 18.9 0.1 2.1 2 0 0 2 2 2 2 START domain FYVE_2 PF02318.16 KDO28522.1 - 0.013 15.7 11.1 0.022 14.9 11.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Bd3614-deam PF14439.6 KDO28522.1 - 0.043 13.9 1.9 0.078 13.0 0.6 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase IBR PF01485.21 KDO28522.1 - 0.76 10.1 12.1 0.31 11.3 9.2 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KDO28523.1 - 0.00034 20.7 9.7 0.00071 19.7 9.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO28523.1 - 0.0033 17.6 3.4 0.0061 16.8 3.4 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger START PF01852.19 KDO28523.1 - 0.0097 15.3 0.1 0.0097 15.3 0.1 2.1 1 1 1 2 2 2 1 START domain zf-B_box PF00643.24 KDO28523.1 - 1.5 9.1 11.5 0.13 12.4 4.9 2.4 3 0 0 3 3 3 0 B-box zinc finger DZR PF12773.7 KDO28523.1 - 1.7 8.7 8.2 11 6.1 8.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 KDO28524.1 - 4.4e-09 36.3 10.9 4.4e-09 36.3 10.9 1.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO28524.1 - 0.0011 19.2 4.7 0.0021 18.3 4.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 KDO28524.1 - 0.0064 16.7 2.7 0.0064 16.7 2.7 2.1 1 1 0 1 1 1 1 IBR domain, a half RING-finger domain DZR PF12773.7 KDO28524.1 - 1.5 8.9 6.7 73 3.5 6.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 KDO28526.1 - 5.8e-07 29.5 11.4 1.4e-06 28.3 11.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO28526.1 - 2.6e-06 27.0 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO28526.1 - 0.0003 21.0 3.9 0.00051 20.2 3.9 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 KDO28526.1 - 0.016 14.9 4.1 0.027 14.1 4.1 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_2 PF13639.6 KDO28526.1 - 0.63 10.4 9.9 1.8 9.0 9.9 1.9 1 0 0 1 1 1 0 Ring finger domain PGM_PMM_IV PF00408.20 KDO28528.1 - 0.086 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain AMP-binding PF00501.28 KDO28529.1 - 1.7e-78 264.1 0.2 3e-78 263.3 0.2 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO28529.1 - 7e-16 59.0 2.9 7.2e-16 58.9 0.8 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO28531.1 - 7.1e-83 278.5 0.0 8.7e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO28531.1 - 4.8e-15 56.3 2.3 2.8e-14 53.9 1.0 2.9 3 1 1 4 4 4 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO28532.1 - 5.4e-83 278.9 0.0 6.9e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO28532.1 - 1.9e-13 51.1 2.1 3.2e-13 50.4 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KDO28533.1 - 3e-38 131.7 0.0 3.6e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28533.1 - 1.5e-21 76.9 0.0 1.8e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO28533.1 - 1.4e-08 34.4 0.0 3.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KDO28533.1 - 0.0019 18.2 0.1 0.0038 17.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family QueF PF14489.6 KDO28533.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein RCC1 PF00415.18 KDO28534.1 - 2.6e-35 120.8 15.4 1.5e-12 47.9 0.7 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KDO28534.1 - 1.7e-32 111.9 0.0 7.3e-17 61.6 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KDO28534.1 - 4.8e-20 70.9 32.7 8.1e-07 28.7 0.5 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KDO28534.1 - 2.7e-11 43.9 0.1 0.00043 20.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28534.1 - 1.9e-07 31.2 3.0 1.8 9.0 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28534.1 - 1.2e-06 29.0 0.5 0.0046 17.5 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28534.1 - 1.2e-06 28.4 2.6 2.8 8.8 0.0 5.9 5 0 0 5 5 5 1 Ankyrin repeat Ion_trans PF00520.31 KDO28534.1 - 0.0055 16.0 18.8 0.0088 15.3 18.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 KDO28534.1 - 0.63 10.6 2.3 97 3.7 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Aa_trans PF01490.18 KDO28535.1 - 8.1e-40 136.8 23.3 1.1e-39 136.4 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_1 PF00232.18 KDO28538.1 - 2.2e-122 408.7 0.0 2.9e-122 408.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 START PF01852.19 KDO28541.1 - 1.1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO28541.1 - 0.00041 20.4 16.7 0.00041 20.4 16.7 2.1 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO28541.1 - 0.0068 16.6 6.8 0.0068 16.6 6.8 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger FA_desaturase PF00487.24 KDO28542.1 - 6.4e-21 75.3 11.3 9.8e-21 74.7 11.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KDO28542.1 - 4.7e-17 61.2 0.1 8.6e-17 60.3 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 KDO28543.1 - 2.1e-23 83.5 9.1 3e-23 83.0 9.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KDO28543.1 - 4.7e-16 58.0 0.0 8.3e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M8 PF01457.16 KDO28543.1 - 0.063 12.0 0.1 0.088 11.5 0.1 1.1 1 0 0 1 1 1 0 Leishmanolysin Kelch_6 PF13964.6 KDO28543.1 - 0.64 10.4 2.6 0.87 10.0 0.6 2.3 2 0 0 2 2 2 0 Kelch motif RhoGEF PF00621.20 KDO28544.1 - 2.4e-23 83.3 0.0 3.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KDO28544.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 PH domain Asn_synthase PF00733.21 KDO28545.1 - 4.9e-98 329.1 1.4 2.5e-57 195.2 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KDO28545.1 - 3.4e-43 146.5 0.0 5.8e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KDO28545.1 - 1.2e-33 116.1 0.0 2.1e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KDO28545.1 - 1.4e-15 57.4 0.1 4e-15 55.9 0.1 1.7 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 KDO28545.1 - 0.066 12.3 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD synthase WW PF00397.26 KDO28546.1 - 2.2e-11 43.6 3.9 3.1e-09 36.8 2.6 2.4 2 0 0 2 2 2 2 WW domain EF-hand_7 PF13499.6 KDO28546.1 - 1.3e-07 31.9 0.0 6.2e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO28546.1 - 3e-07 29.8 0.0 0.00071 19.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KDO28546.1 - 5.1e-06 25.7 0.1 0.00041 19.7 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KDO28546.1 - 0.0048 16.7 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO28546.1 - 0.012 15.1 0.1 0.069 12.7 0.1 2.2 2 0 0 2 2 2 0 EF hand DUF2481 PF10654.9 KDO28546.1 - 0.12 12.4 0.3 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) zf-RVT PF13966.6 KDO28547.1 - 2e-05 25.2 1.2 4.9e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase Metallophos PF00149.28 KDO28549.1 - 2.1e-14 54.5 6.4 2.1e-14 54.5 6.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO28549.1 - 3.3e-05 24.1 2.7 3.5e-05 24.1 1.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.6 KDO28549.1 - 0.086 11.4 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 MutL protein PALP PF00291.25 KDO28551.1 - 9.7e-60 202.5 0.0 1.3e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KDO28551.1 - 1.4e-12 47.9 0.2 5.8e-07 29.9 0.1 2.8 2 0 0 2 2 2 2 CBS domain FYVE PF01363.21 KDO28552.1 - 2.2e-10 40.5 6.4 2.2e-10 40.5 6.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 KDO28552.1 - 0.0027 18.2 0.1 0.013 16.0 0.1 2.1 2 0 0 2 2 2 1 PH domain C1_2 PF03107.16 KDO28552.1 - 0.1 13.0 3.0 0.31 11.4 3.0 1.9 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 KDO28552.1 - 0.26 11.5 4.7 0.84 9.9 4.7 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Pkinase_Tyr PF07714.17 KDO28553.1 - 8e-42 143.3 0.0 9.9e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28553.1 - 2e-37 129.0 0.0 2.5e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KDO28554.1 - 2.7e-35 122.0 0.0 3.7e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28554.1 - 4.8e-35 121.1 0.0 6.4e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO28554.1 - 0.005 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO28554.1 - 0.082 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Myb_DNA-bind_6 PF13921.6 KDO28555.1 - 1.8e-15 56.9 1.0 1.5e-08 34.8 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO28555.1 - 5e-10 39.4 2.4 0.00014 22.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KDO28555.1 - 0.00025 21.3 5.5 0.0068 16.8 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Atg29_N PF18388.1 KDO28555.1 - 0.024 14.4 0.2 0.75 9.7 0.0 2.7 2 0 0 2 2 2 0 Atg29 N-terminal domain Ank_2 PF12796.7 KDO28556.1 - 3.3e-26 91.7 2.9 1.8e-10 41.3 0.3 6.2 4 3 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28556.1 - 1.1e-19 70.3 13.7 0.023 15.0 0.0 11.0 5 3 7 12 12 12 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28556.1 - 2e-19 69.7 15.5 1.2e-05 25.7 0.1 8.8 7 2 4 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28556.1 - 3.9e-12 45.2 10.7 0.1 13.2 0.1 9.7 8 2 2 10 10 10 3 Ankyrin repeat Ank PF00023.30 KDO28556.1 - 5.6e-06 26.6 10.4 1.5 9.4 0.0 7.8 7 2 2 9 9 9 2 Ankyrin repeat Ank_2 PF12796.7 KDO28557.1 - 2.9e-16 59.8 7.0 0.00012 22.5 0.4 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28557.1 - 1.2e-13 51.2 5.2 0.0017 18.9 0.0 6.1 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28557.1 - 7.7e-12 45.2 12.1 0.17 12.3 0.0 7.6 3 2 5 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28557.1 - 7.9e-07 28.9 4.3 19 6.2 0.1 7.6 5 1 3 8 8 8 1 Ankyrin repeat Ank PF00023.30 KDO28557.1 - 0.028 14.9 1.8 39 4.9 0.0 5.6 3 2 1 5 5 5 0 Ankyrin repeat GlutR_dimer PF00745.20 KDO28557.1 - 0.11 13.0 2.5 0.36 11.3 0.5 2.4 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ank_3 PF13606.6 KDO28558.1 - 0.00056 20.1 0.1 0.75 10.6 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO28558.1 - 0.00076 20.0 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28558.1 - 0.037 14.6 0.1 0.35 11.5 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28558.1 - 0.055 13.8 0.0 18 5.8 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28559.1 - 3.1e-21 75.8 14.7 1.3e-08 35.3 0.3 5.9 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28559.1 - 1.4e-16 60.3 15.8 0.0035 17.6 0.0 9.6 3 3 7 10 10 10 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28559.1 - 5.9e-13 49.1 16.6 0.00094 19.7 0.2 8.0 6 3 4 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28559.1 - 1.7e-08 34.0 11.0 3 8.7 0.0 9.9 8 3 2 10 10 10 1 Ankyrin repeat Ank PF00023.30 KDO28559.1 - 1.8e-07 31.3 8.8 0.041 14.3 0.1 7.6 3 2 3 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 KDO28560.1 - 2e-20 73.2 0.6 9.6e-07 29.3 0.0 5.4 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28560.1 - 4.3e-17 61.9 13.0 0.021 15.1 0.0 9.5 6 2 4 10 10 10 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28560.1 - 8.1e-17 61.4 6.8 0.00017 22.1 0.1 7.4 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28560.1 - 9.2e-11 41.0 6.5 0.2 12.3 0.0 7.8 7 1 1 8 8 8 3 Ankyrin repeat Ank PF00023.30 KDO28560.1 - 1.7e-07 31.4 2.3 6 7.5 0.0 6.8 5 2 1 6 6 6 3 Ankyrin repeat NAM-associated PF14303.6 KDO28561.1 - 6.6e-15 56.2 0.3 6.6e-15 56.2 0.3 2.9 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain ActA PF05058.12 KDO28561.1 - 0.0059 15.0 0.2 0.0069 14.8 0.2 1.2 1 0 0 1 1 1 1 ActA Protein Ribophorin_II PF05817.14 KDO28561.1 - 0.015 13.9 0.1 0.018 13.6 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Ank_2 PF12796.7 KDO28562.1 - 1.6e-16 60.7 4.4 5.6e-05 23.7 0.2 6.4 3 3 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28562.1 - 4.5e-12 46.2 10.6 0.00014 22.4 0.1 7.5 4 4 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28562.1 - 1.4e-10 41.2 7.9 9.5 6.7 0.0 9.4 4 3 6 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28562.1 - 0.00026 21.2 7.0 5.9 7.8 0.0 7.0 7 1 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 KDO28562.1 - 0.0088 16.5 7.2 28 5.4 0.0 6.3 5 1 2 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 KDO28563.1 - 2.3e-19 69.8 8.4 9.2e-08 32.6 0.1 5.8 3 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28563.1 - 5.1e-17 62.0 15.2 4.4e-05 24.0 0.0 7.5 7 2 1 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28563.1 - 2.3e-14 53.2 15.9 0.024 15.0 0.2 9.5 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28563.1 - 1.7e-10 40.2 6.8 0.38 11.5 0.0 9.3 9 1 1 10 10 10 1 Ankyrin repeat Ank PF00023.30 KDO28563.1 - 6.5e-07 29.5 5.7 1.9 9.1 0.1 7.5 4 2 3 8 8 8 1 Ankyrin repeat Peptidase_C23 PF05379.11 KDO28563.1 - 0.062 13.4 0.2 0.57 10.3 0.1 2.4 2 0 0 2 2 2 0 Carlavirus endopeptidase DUF1707 PF08044.11 KDO28563.1 - 0.17 12.0 11.4 16 5.6 0.0 5.9 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) Ank_2 PF12796.7 KDO28564.1 - 5.7e-42 142.2 13.9 4.9e-13 49.5 0.4 7.5 5 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28564.1 - 8.1e-36 122.0 13.0 3.5e-08 33.8 0.1 9.1 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28564.1 - 1.6e-31 104.8 10.6 0.0015 18.8 0.0 12.1 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 KDO28564.1 - 5.8e-31 106.2 16.2 5.2e-06 26.6 0.1 9.4 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO28564.1 - 2.5e-22 78.2 17.0 0.0037 17.6 0.0 10.3 9 0 0 9 9 9 5 Ankyrin repeat Ion_trans PF00520.31 KDO28564.1 - 5.4e-10 38.9 22.0 5.4e-10 38.9 22.0 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO28564.1 - 0.00025 19.8 17.7 0.00084 18.1 9.6 2.3 1 1 1 2 2 2 2 Polycystin cation channel DUF148 PF02520.17 KDO28564.1 - 1.5 8.9 5.7 3.6 7.7 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF148 Myb_DNA-binding PF00249.31 KDO28565.1 - 1.4e-34 118.0 3.2 4.6e-11 42.7 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO28565.1 - 6.3e-33 112.8 1.0 4.5e-14 52.4 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 KDO28565.1 - 0.0011 19.0 0.0 1.7 8.7 0.0 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KDO28565.1 - 0.0016 18.8 2.7 2.1 8.8 0.2 3.4 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO28565.1 - 0.0024 17.7 0.0 0.007 16.2 0.0 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Atg29_N PF18388.1 KDO28565.1 - 0.0034 17.2 0.5 0.24 11.3 0.0 3.0 3 0 0 3 3 3 1 Atg29 N-terminal domain DUF1499 PF07386.11 KDO28566.1 - 0.061 13.9 1.3 1.4 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1499) DUF737 PF05300.11 KDO28566.1 - 0.47 10.8 11.2 0.66 10.3 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2828 PF11443.8 KDO28567.1 - 1.5e-103 347.1 0.5 1.9e-82 277.3 0.3 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 KDO28567.1 - 1.7e-05 24.3 0.0 3.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Flavodoxin_NdrI PF07972.11 KDO28567.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like Rdx PF10262.9 KDO28568.1 - 1.4e-08 34.8 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Rdx family zf-PARP PF00645.18 KDO28570.1 - 3.5e-08 34.2 0.0 4.6e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MOZ_SAS PF01853.18 KDO28571.1 - 4.4e-80 267.6 0.6 6.5e-80 267.0 0.6 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KDO28571.1 - 4.6e-19 67.8 0.4 4.6e-19 67.8 0.4 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 KDO28571.1 - 2.6e-15 56.0 0.7 5.2e-15 55.1 0.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KDO28571.1 - 0.058 13.3 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SPARC_Ca_bdg PF10591.9 KDO28571.1 - 0.2 12.0 1.6 5.6 7.3 0.3 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FCP1_C PF09309.10 KDO28571.1 - 0.68 9.8 10.0 1.1 9.1 10.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal SesA PF17107.5 KDO28572.1 - 0.09 13.0 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LRR_8 PF13855.6 KDO28573.1 - 1.7e-23 82.1 24.0 1.5e-09 37.4 1.8 3.5 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KDO28573.1 - 9e-16 57.7 10.1 0.00028 21.2 3.1 4.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO28573.1 - 0.00012 22.1 6.0 2.6 8.9 0.3 5.9 5 1 1 6 6 6 1 Leucine Rich Repeat Penicillinase_R PF03965.16 KDO28573.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Penicillinase repressor LRR_9 PF14580.6 KDO28573.1 - 0.018 14.5 7.0 0.026 14.0 0.4 2.5 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 KDO28573.1 - 0.12 12.5 15.0 7.2 6.9 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich repeat SPO22 PF08631.10 KDO28575.1 - 4.9e-06 26.2 0.5 1.9e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KDO28575.1 - 0.0018 18.7 3.4 0.033 14.7 0.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28575.1 - 0.0044 17.7 1.7 2.7 9.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO28575.1 - 0.017 15.4 3.8 10 6.5 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO28575.1 - 0.045 14.0 0.5 8.2 6.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28575.1 - 0.056 13.5 5.8 6 7.1 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28575.1 - 0.11 12.7 4.6 35 4.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO28575.1 - 0.15 12.7 2.2 11 7.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat 5_3_exonuc_N PF02739.16 KDO28576.1 - 1.8e-31 109.2 0.0 2.5e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KDO28576.1 - 4.6e-08 33.6 0.0 7.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold NYN_YacP PF05991.11 KDO28576.1 - 0.067 13.1 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 YacP-like NYN domain DUF2828 PF11443.8 KDO28577.1 - 8.8e-104 347.8 1.0 7.4e-83 278.7 0.6 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 KDO28577.1 - 3.7e-06 26.5 0.0 8.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Flavodoxin_NdrI PF07972.11 KDO28577.1 - 0.019 15.2 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Ank_2 PF12796.7 KDO28578.1 - 1.7e-23 83.0 1.5 1.3e-07 32.0 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28578.1 - 1.7e-18 66.7 7.8 2.2e-05 24.9 0.0 7.2 6 2 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28578.1 - 5.8e-12 45.6 17.3 0.012 15.9 0.0 9.5 5 3 7 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28578.1 - 9.2e-08 31.8 9.0 1.6 9.6 0.0 8.6 7 2 2 9 9 9 2 Ankyrin repeat Ank PF00023.30 KDO28578.1 - 4e-05 23.9 5.1 0.16 12.5 0.0 6.5 5 2 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KDO28579.1 - 0.16 12.3 0.1 8 6.9 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28580.1 - 1.9e-13 50.8 2.0 8.5e-07 29.5 0.4 5.1 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28580.1 - 1.5e-12 47.4 4.4 0.0055 17.0 0.0 6.2 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28580.1 - 9.1e-11 42.1 5.1 0.0003 21.3 0.1 6.1 4 3 5 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28580.1 - 2e-07 30.7 2.0 9.1 7.2 0.0 7.4 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 KDO28580.1 - 4.8e-06 26.8 0.3 4.6 7.9 0.0 5.0 4 2 0 4 4 4 3 Ankyrin repeat DUF1707 PF08044.11 KDO28580.1 - 0.02 14.9 0.1 19 5.4 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) Unstab_antitox PF09720.10 KDO28581.1 - 0.23 11.5 0.9 2.4 8.3 0.3 2.2 1 1 1 2 2 2 0 Putative addiction module component Ank_2 PF12796.7 KDO28582.1 - 4.5e-25 88.0 6.1 2.2e-05 24.9 0.2 5.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28582.1 - 1.7e-19 69.9 11.2 4.6e-06 27.1 0.1 8.3 6 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28582.1 - 5.7e-17 61.6 10.2 0.00026 21.2 0.0 9.4 4 2 6 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO28582.1 - 1e-09 38.4 0.4 0.36 11.4 0.0 7.4 3 2 2 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KDO28582.1 - 1.2e-06 28.3 4.8 10 7.1 0.0 9.0 8 3 2 10 10 10 1 Ankyrin repeat Ank_2 PF12796.7 KDO28583.1 - 2.2e-22 79.4 8.1 3.2e-07 30.8 0.3 6.3 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28583.1 - 1e-17 63.9 13.3 0.027 14.8 0.0 9.3 4 3 6 10 10 10 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28583.1 - 8e-16 58.2 19.0 0.0014 19.2 0.0 8.4 5 3 7 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28583.1 - 3.9e-12 45.2 8.6 1 10.1 0.1 9.9 7 2 3 10 10 10 4 Ankyrin repeat Ank PF00023.30 KDO28583.1 - 1.1e-05 25.6 12.6 3.4 8.3 1.7 8.8 7 2 0 7 7 7 2 Ankyrin repeat zf-RING_2 PF13639.6 KDO28584.1 - 3.4e-11 43.3 6.5 5.3e-11 42.7 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO28584.1 - 5e-11 42.1 1.7 8.9e-11 41.3 1.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO28584.1 - 2.6e-09 36.9 2.8 6e-09 35.8 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KDO28584.1 - 4.2e-08 33.4 7.9 2.2e-07 31.0 7.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO28584.1 - 7.3e-08 32.1 7.6 1.4e-07 31.2 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO28584.1 - 1.3e-07 31.4 6.6 2.2e-07 30.7 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO28584.1 - 9.5e-05 22.3 4.3 0.00017 21.5 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO28584.1 - 0.0002 21.2 3.3 0.00032 20.5 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO28584.1 - 0.0036 17.4 2.0 0.01 16.0 2.0 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KDO28584.1 - 0.026 14.2 2.8 0.043 13.4 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type U-box PF04564.15 KDO28584.1 - 0.033 14.4 0.5 0.079 13.1 0.0 2.0 2 1 0 2 2 2 0 U-box domain Prok-RING_1 PF14446.6 KDO28584.1 - 0.051 13.5 2.9 0.093 12.7 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 KDO28584.1 - 0.17 11.8 3.4 0.4 10.6 3.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.11 KDO28584.1 - 0.19 11.7 0.9 0.32 11.0 0.9 1.4 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-ANAPC11 PF12861.7 KDO28584.1 - 0.37 10.9 4.0 0.39 10.8 2.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger LRR_8 PF13855.6 KDO28585.1 - 6e-10 38.7 1.2 7.5e-07 28.8 0.5 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO28585.1 - 9e-08 32.3 0.1 3.3e-05 24.2 0.0 3.2 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO28585.1 - 3.9e-06 26.5 0.0 8.2e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat GCIP PF13324.6 KDO28585.1 - 0.64 9.6 5.1 1.2 8.7 5.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 KDO28585.1 - 1.7 9.1 10.2 6.6 7.2 10.2 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KDO28585.1 - 2.1 8.0 6.7 3.6 7.2 6.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UCH PF00443.29 KDO28586.1 - 5.8e-43 147.2 0.0 1.1e-42 146.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO28586.1 - 6.6e-17 62.1 0.0 9.7e-16 58.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KDO28586.1 - 0.2 11.4 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family zf-RING_11 PF17123.5 KDO28587.1 - 0.00022 20.9 0.4 0.00057 19.6 0.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO28587.1 - 0.0035 17.6 4.2 0.0083 16.4 4.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KDO28587.1 - 0.014 15.7 7.4 0.033 14.5 7.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KDO28587.1 - 0.028 14.2 8.4 0.14 12.0 8.6 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO28587.1 - 0.12 12.2 7.8 0.3 11.0 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO28587.1 - 0.14 12.0 8.1 0.3 11.0 8.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KDO28587.1 - 0.19 11.8 7.1 0.45 10.6 7.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO28587.1 - 0.24 11.5 2.4 0.69 10.0 2.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO28587.1 - 1.4 8.9 9.3 3.7 7.6 9.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain BTB_2 PF02214.22 KDO28588.1 - 4.8e-14 52.5 0.0 8.8e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 KDO28588.1 - 9.9e-05 22.4 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOAR PF16533.5 KDO28588.1 - 0.0026 17.7 3.0 0.0056 16.6 3.0 1.5 1 0 0 1 1 1 1 STIM1 Orai1-activating region RWP-RK PF02042.15 KDO28588.1 - 0.11 12.5 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 RWP-RK domain Exonuc_VII_L PF02601.15 KDO28588.1 - 0.13 11.8 0.5 0.18 11.3 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 KDO28588.1 - 0.14 12.0 10.9 0.23 11.3 10.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2807 PF10988.8 KDO28588.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain CREPT PF16566.5 KDO28588.1 - 0.17 12.1 4.0 0.27 11.4 4.0 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1690 PF07956.11 KDO28588.1 - 1.5 9.2 6.1 22 5.4 7.2 2.2 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) FAM184 PF15665.5 KDO28588.1 - 1.6 8.4 9.7 3.8 7.2 9.7 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B AIRS_C PF02769.22 KDO28589.1 - 4.6e-08 33.3 0.1 9.6e-07 29.1 0.1 2.4 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KDO28589.1 - 0.0053 17.4 0.2 0.015 16.0 0.2 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Peptidase_C1 PF00112.23 KDO28590.1 - 4.1e-59 200.3 12.4 4.1e-59 200.3 12.4 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO28590.1 - 3.9e-05 22.6 2.5 0.027 13.2 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family ABC_membrane PF00664.23 KDO28591.1 - 1.8e-49 168.8 29.4 7.1e-25 88.2 9.5 4.1 2 2 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO28591.1 - 4e-44 150.4 0.1 3.1e-17 63.4 0.0 3.3 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 KDO28591.1 - 3e-06 26.9 6.8 0.045 13.2 0.1 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO28591.1 - 8.2e-06 25.9 0.8 0.073 13.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO28591.1 - 9.3e-05 22.4 0.1 0.53 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO28591.1 - 9.4e-05 22.1 0.2 0.45 10.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO28591.1 - 0.00041 20.8 0.4 0.87 10.0 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KDO28591.1 - 0.0008 19.5 2.7 0.12 12.4 0.2 2.4 2 0 0 2 2 2 2 Dynamin family AAA_21 PF13304.6 KDO28591.1 - 0.0017 18.2 0.6 3.2 7.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KDO28591.1 - 0.0035 16.7 0.7 0.78 9.0 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MeaB PF03308.16 KDO28591.1 - 0.0039 16.2 0.8 1.8 7.5 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 KDO28591.1 - 0.0067 15.6 0.8 0.53 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 KDO28591.1 - 0.014 15.5 3.3 0.072 13.2 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KDO28591.1 - 0.026 13.5 0.2 3.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KDO28591.1 - 0.038 13.7 0.1 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO28591.1 - 0.046 13.2 0.2 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KDO28591.1 - 0.08 13.1 1.2 1.9 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KDO28591.1 - 0.094 12.4 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 KDO28591.1 - 0.2 11.9 1.2 8.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KDO28591.1 - 0.28 10.9 0.7 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KDO28591.1 - 0.3 10.3 0.5 8.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KDO28591.1 - 0.37 10.4 2.7 3.1 7.4 0.2 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KDO28591.1 - 0.64 10.3 1.8 29 4.9 0.1 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KDO28591.1 - 1.2 9.1 5.2 3.5 7.5 0.1 2.8 3 0 0 3 3 3 0 NACHT domain Ank_2 PF12796.7 KDO28592.1 - 5.3e-15 55.8 0.5 2.7e-05 24.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28592.1 - 1.3e-11 44.7 3.2 2.1e-05 25.0 0.2 5.0 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28592.1 - 5e-09 36.2 5.2 0.058 13.7 0.1 7.0 3 2 5 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28592.1 - 1.2e-06 28.3 0.7 5.5 7.9 0.0 6.1 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 KDO28592.1 - 4.6e-05 23.7 4.0 0.081 13.4 0.1 4.9 3 1 1 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KDO28593.1 - 4.6e-21 75.2 15.7 6.1e-08 33.1 0.0 6.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28593.1 - 4.6e-17 62.1 14.7 0.00076 20.0 1.7 7.3 4 3 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28593.1 - 8.6e-16 57.8 17.8 0.092 13.1 0.0 9.3 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28593.1 - 2e-07 30.7 13.2 4.4 8.2 0.0 10.1 9 2 2 11 11 11 2 Ankyrin repeat Ank PF00023.30 KDO28593.1 - 0.00012 22.3 8.1 2.4 8.8 0.0 7.3 3 1 2 5 5 5 1 Ankyrin repeat YAcAr PF10686.9 KDO28593.1 - 0.012 15.6 0.8 0.061 13.3 0.8 2.3 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Pkinase_Tyr PF07714.17 KDO28594.1 - 3.9e-10 39.4 0.8 3.6e-07 29.7 0.3 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO28594.1 - 0.00012 21.6 0.3 0.00029 20.3 0.2 1.5 1 1 1 2 2 2 1 Protein kinase domain CLP1_P PF16575.5 KDO28594.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop 2OG-FeII_Oxy_3 PF13640.6 KDO28595.1 - 7.8e-13 49.1 0.1 1.4e-12 48.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 KDO28595.1 - 0.017 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein 2OG-FeII_Oxy_3 PF13640.6 KDO28596.1 - 1.4e-11 45.1 0.0 2.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 KDO28596.1 - 0.044 12.9 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein DUF3712 PF12505.8 KDO28597.1 - 1.8e-34 118.7 0.5 2e-13 50.7 0.1 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KDO28597.1 - 0.0037 17.8 0.0 7.8 7.1 0.0 4.8 4 0 0 4 4 4 1 Late embryogenesis abundant protein EF-hand_1 PF00036.32 KDO28599.1 - 3.3e-13 48.2 5.6 2.3e-06 26.7 1.1 4.3 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO28599.1 - 4.8e-12 44.8 4.5 0.001 18.8 0.4 4.6 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KDO28599.1 - 1e-05 24.8 0.6 0.0018 17.7 0.2 3.1 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KDO28599.1 - 9.2e-05 22.8 3.2 0.036 14.5 0.7 3.8 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 KDO28599.1 - 0.00094 19.1 1.0 0.011 15.7 0.5 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 KDO28599.1 - 0.08 12.8 7.9 1.3 8.9 1.0 3.9 4 0 0 4 4 4 0 EF-hand domain pair Glyco_transf_41 PF13844.6 KDO28601.1 - 1.3e-12 47.0 0.3 2.3e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 KDO28601.1 - 6.1e-09 35.3 8.5 0.0004 20.3 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO28601.1 - 2.8e-08 33.3 0.1 3.8e-05 23.6 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO28601.1 - 1.9e-05 24.7 8.5 0.0029 17.9 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28601.1 - 1.9e-05 24.4 1.2 0.027 14.5 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO28601.1 - 8.3e-05 22.3 6.9 0.00021 21.0 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO28601.1 - 0.00017 22.1 30.0 0.15 12.7 2.3 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO28601.1 - 0.00028 21.1 16.1 0.00083 19.6 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO28601.1 - 0.0051 16.5 0.7 0.0051 16.5 0.7 3.3 4 0 0 4 4 4 1 TPR repeat TPR_9 PF13371.6 KDO28601.1 - 0.025 14.7 0.7 0.025 14.7 0.7 2.8 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO28601.1 - 2.1 8.3 13.6 0.8 9.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28601.1 - 6.4 7.9 26.7 3.6 8.6 0.7 6.4 3 2 3 6 6 6 0 Tetratricopeptide repeat EamA PF00892.20 KDO28602.1 - 6e-19 68.6 40.1 9.4e-15 55.0 15.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family RseC_MucC PF04246.12 KDO28602.1 - 0.033 14.1 0.5 0.033 14.1 0.5 3.4 1 1 2 4 4 4 0 Positive regulator of sigma(E), RseC/MucC TPT PF03151.16 KDO28602.1 - 0.056 12.8 14.8 0.02 14.3 9.6 2.4 1 1 1 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.20 KDO28603.1 - 1.5e-16 60.8 38.1 2.3e-14 53.7 15.1 2.3 2 1 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 KDO28604.1 - 3.1e-17 63.0 42.0 1.8e-13 50.9 19.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 KDO28605.1 - 6.9e-19 68.4 40.1 1.9e-13 50.8 16.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLATT_1 PF18181.1 KDO28605.1 - 2.7 7.9 6.3 0.26 11.2 0.5 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 EamA PF00892.20 KDO28606.1 - 1.4e-17 64.1 38.0 1.1e-08 35.3 14.8 3.0 2 1 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 KDO28607.1 - 8.9e-19 68.0 41.6 1.3e-12 48.0 20.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO28607.1 - 0.0027 17.1 16.9 0.0098 15.3 16.9 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family QCR10 PF09796.9 KDO28607.1 - 0.088 12.9 0.9 8.7 6.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Multi_Drug_Res PF00893.19 KDO28607.1 - 0.35 11.6 21.9 0.49 11.1 3.0 3.3 2 2 1 3 3 3 0 Small Multidrug Resistance protein DUF3290 PF11694.8 KDO28607.1 - 1.9 8.5 6.4 4.1 7.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) EamA PF00892.20 KDO28608.1 - 1.2e-17 64.3 41.5 2.4e-12 47.2 16.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO28608.1 - 4.2e-05 23.1 3.5 4.2e-05 23.1 3.5 2.1 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 KDO28608.1 - 0.00058 19.2 3.1 0.15 11.2 0.7 2.4 2 0 0 2 2 2 2 UAA transporter family Multi_Drug_Res PF00893.19 KDO28608.1 - 0.066 13.9 17.0 0.68 10.6 2.8 3.3 3 1 0 3 3 3 0 Small Multidrug Resistance protein EamA PF00892.20 KDO28609.1 - 2.1e-21 76.5 40.1 7.9e-14 52.0 16.9 2.0 2 0 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 KDO28610.1 - 8e-15 55.2 37.2 2.7e-09 37.3 12.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 KDO28610.1 - 0.36 11.5 22.4 0.13 13.0 5.5 3.2 2 2 1 3 3 3 0 Small Multidrug Resistance protein EamA PF00892.20 KDO28611.1 - 1.1e-16 61.2 44.9 6.1e-12 45.9 18.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family Ferric_reduct PF01794.19 KDO28612.1 - 3.4e-12 46.6 15.7 3.4e-12 46.6 15.7 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO28612.1 - 6.4e-10 39.4 0.1 0.0013 18.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO28612.1 - 5e-07 29.8 0.0 9.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DOMON PF03351.17 KDO28612.1 - 2.8e-06 27.6 0.1 4.7e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 DOMON domain NAD_binding_1 PF00175.21 KDO28612.1 - 0.0095 16.6 0.2 0.11 13.2 0.1 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 KDO28612.1 - 0.3 11.7 18.6 0.43 11.2 8.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) PLAC8 PF04749.17 KDO28613.1 - 6.8e-12 46.3 1.6 9.3e-12 45.8 1.6 1.2 1 0 0 1 1 1 1 PLAC8 family Ank_2 PF12796.7 KDO28614.1 - 4.2e-25 88.1 5.2 7.8e-07 29.6 0.1 6.8 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28614.1 - 6.3e-15 55.0 18.6 2.3e-05 24.6 0.1 9.0 4 3 4 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28614.1 - 6.9e-15 55.2 16.4 1e-06 29.2 0.0 8.5 9 2 2 11 11 11 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO28614.1 - 7.9e-07 29.3 1.0 0.56 10.7 0.0 6.9 5 2 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 KDO28614.1 - 2.9e-06 27.2 23.8 0.13 12.9 0.0 11.6 12 1 2 14 14 14 1 Ankyrin repeat Ank_2 PF12796.7 KDO28615.1 - 7.2e-23 81.0 13.5 2.1e-06 28.2 0.5 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28615.1 - 1.3e-16 60.4 19.4 0.0038 17.5 0.0 9.9 5 3 6 12 12 12 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28615.1 - 2.7e-15 56.5 18.4 0.001 19.6 0.1 9.1 5 2 6 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28615.1 - 8.2e-11 41.2 15.5 3.6 8.5 0.0 10.4 10 1 1 11 11 11 3 Ankyrin repeat Ank PF00023.30 KDO28615.1 - 2.7e-05 24.4 10.7 0.33 11.5 0.0 6.9 4 2 2 6 6 6 1 Ankyrin repeat TPR_12 PF13424.6 KDO28616.1 - 6e-06 26.5 3.5 0.0086 16.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28616.1 - 0.036 14.2 0.1 6 7.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO28616.1 - 0.18 12.5 0.7 1.7 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 KDO28617.1 - 4.8e-59 196.3 6.3 5.3e-23 80.8 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO28617.1 - 0.00016 21.0 3.0 0.0025 17.0 0.2 2.9 2 1 1 3 3 3 2 Gammaproteobacterial serine protease Cyt-b5 PF00173.28 KDO28618.1 - 1.8e-06 28.0 0.1 3.6e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cys_Met_Meta_PP PF01053.20 KDO28619.1 - 3.5e-135 450.4 0.0 4e-135 450.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KDO28619.1 - 3.2e-08 32.9 0.1 1.5e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KDO28619.1 - 1.5e-05 24.5 0.1 3.5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KDO28619.1 - 0.00022 20.5 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 KDO28619.1 - 0.068 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein COX5A PF02284.16 KDO28620.1 - 0.00061 19.7 0.2 0.048 13.7 0.0 3.0 3 0 0 3 3 3 2 Cytochrome c oxidase subunit Va Fz PF01392.22 KDO28622.1 - 0.056 14.1 7.9 0.18 12.4 7.9 1.9 1 1 0 1 1 1 0 Fz domain zf-CCHC PF00098.23 KDO28624.1 - 0.0027 17.7 5.2 0.0044 17.0 5.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C4H2 PF10146.9 KDO28624.1 - 0.0057 17.0 0.7 0.0057 17.0 0.7 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein NUDE_C PF04880.13 KDO28627.1 - 0.042 14.3 0.3 0.042 14.3 0.3 5.8 3 1 2 6 6 6 0 NUDE protein, C-terminal conserved region DUF2459 PF09601.10 KDO28627.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2459) HALZ PF02183.18 KDO28627.1 - 5 7.4 45.0 2.3 8.5 3.0 9.0 8 0 0 8 8 8 0 Homeobox associated leucine zipper NIF PF03031.18 KDO28629.1 - 1.1e-51 174.7 0.6 1.6e-51 174.1 0.6 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KDO28629.1 - 0.00047 20.6 0.1 0.0036 17.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Replicase PF03090.17 KDO28629.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Replicase family Acid_phosphat_B PF03767.14 KDO28629.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PBP PF01161.20 KDO28630.1 - 5.9e-10 39.6 0.6 7.8e-10 39.2 0.6 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATG7_N PF16420.5 KDO28631.1 - 4e-67 227.0 0.0 5e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KDO28631.1 - 2e-48 164.9 0.0 3.1e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KDO28631.1 - 0.02 15.0 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_2 PF13347.6 KDO28633.1 - 8.9e-12 44.3 26.2 4.4e-11 42.0 11.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KDO28633.1 - 1.9e-08 33.7 50.6 5.2e-07 28.9 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0239 PF06783.11 KDO28633.1 - 0.35 11.1 0.7 16 5.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) Popeye PF04831.13 KDO28633.1 - 3.7 7.7 5.4 0.65 10.2 0.8 2.2 2 0 0 2 2 2 0 Popeye protein conserved region Ras PF00071.22 KDO28634.1 - 4.7e-39 133.6 0.1 1.1e-37 129.1 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KDO28634.1 - 2e-26 92.5 0.0 9.5e-25 87.1 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO28634.1 - 2.1e-11 43.6 0.0 7.5e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO28634.1 - 0.00014 21.9 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO28634.1 - 0.00062 19.4 0.1 0.00092 18.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KDO28634.1 - 0.0048 16.8 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 MCM PF00493.23 KDO28634.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 KDO28634.1 - 0.018 15.3 0.0 0.041 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO28634.1 - 0.03 14.7 0.1 0.057 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KDO28634.1 - 0.042 13.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 KDO28634.1 - 0.045 13.7 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KDO28634.1 - 0.052 13.1 0.0 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KDO28634.1 - 0.065 12.9 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KDO28634.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 KDO28634.1 - 0.14 12.6 0.1 0.23 11.9 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 KDO28634.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KDO28634.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PAN_1 PF00024.26 KDO28635.1 - 2.3e-14 53.1 12.1 2.3e-05 24.3 0.6 3.9 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 KDO28635.1 - 2.3e-12 46.6 24.1 7.1e-05 22.6 4.6 3.7 3 0 0 3 3 3 3 PAN domain Tyrosinase PF00264.20 KDO28635.1 - 0.0029 17.9 0.6 0.37 11.0 0.0 3.1 4 0 0 4 4 4 1 Common central domain of tyrosinase LSM PF01423.22 KDO28636.1 - 4.8e-12 45.4 0.0 9e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 LSM domain MatE PF01554.18 KDO28638.1 - 6.3e-40 136.5 32.4 1.2e-22 80.2 10.4 2.4 2 0 0 2 2 2 2 MatE FKBP_C PF00254.28 KDO28640.1 - 7.4e-28 96.7 0.0 1.2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KDO28640.1 - 4.1e-21 72.9 2.3 4.6e-07 28.9 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO28640.1 - 1.2e-16 59.1 2.4 2.9e-06 26.7 0.1 3.9 4 0 0 4 4 3 3 EF-hand domain EF-hand_5 PF13202.6 KDO28640.1 - 2e-16 58.6 3.8 1.2e-06 27.8 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KDO28640.1 - 6.8e-15 55.3 0.1 2.9e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO28640.1 - 1.9e-10 40.4 2.2 3.4e-05 23.6 0.1 3.2 2 1 2 4 4 4 3 EF-hand domain pair WW PF00397.26 KDO28640.1 - 2.2e-07 30.8 1.8 4e-07 30.0 1.8 1.4 1 0 0 1 1 1 1 WW domain EF-hand_9 PF14658.6 KDO28640.1 - 1.4e-05 25.3 0.1 0.057 13.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain IQ PF00612.27 KDO28640.1 - 0.0019 17.8 1.5 0.0063 16.2 1.5 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif SPARC_Ca_bdg PF10591.9 KDO28640.1 - 0.053 13.8 2.6 0.98 9.8 0.0 2.7 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_S46 PF10459.9 KDO28640.1 - 0.3 9.7 5.0 5.5 5.5 1.4 2.4 1 1 1 2 2 2 0 Peptidase S46 Casc1_N PF15927.5 KDO28640.1 - 0.56 9.9 12.5 1.4 8.5 12.5 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus WD40 PF00400.32 KDO28642.1 - 4.4e-16 59.0 10.2 0.00083 20.1 0.5 9.4 9 1 2 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28642.1 - 3.5e-06 27.2 0.0 1 9.7 0.0 6.0 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain KASH_CCD PF14662.6 KDO28642.1 - 0.0015 18.4 18.6 0.0015 18.4 18.6 5.8 2 2 5 7 7 7 4 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KDO28642.1 - 0.0045 17.0 13.3 0.0045 17.0 13.3 6.4 2 2 4 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Metallophos PF00149.28 KDO28643.1 - 1.4e-32 113.9 0.0 2.3e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KDO28643.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) STPPase_N PF16891.5 KDO28643.1 - 0.017 15.5 0.2 0.032 14.7 0.2 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Queuosine_synth PF02547.15 KDO28644.1 - 5e-94 315.0 0.0 5.8e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein GRDP-like PF07173.12 KDO28646.1 - 6.3e-17 62.6 0.1 2.5e-16 60.6 0.1 2.1 1 1 1 2 2 2 1 Glycine-rich domain-containing protein-like DZR PF12773.7 KDO28646.1 - 9.7 6.3 8.0 56 3.9 5.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon GRDP-like PF07173.12 KDO28647.1 - 1.3e-16 61.6 0.0 4.4e-16 59.8 0.0 1.9 1 1 1 2 2 2 1 Glycine-rich domain-containing protein-like Helicase_C_2 PF13307.6 KDO28648.1 - 1.3e-57 194.7 0.0 1.4e-56 191.3 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KDO28648.1 - 1.5e-49 168.0 0.4 2.6e-49 167.2 0.4 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KDO28648.1 - 0.00033 20.7 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 KDO28648.1 - 0.028 13.9 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ZapB PF06005.12 KDO28649.1 - 0.00022 21.6 35.6 0.17 12.3 0.7 6.3 5 1 1 6 6 6 4 Cell division protein ZapB Filament PF00038.21 KDO28649.1 - 0.0018 18.0 15.7 0.0018 18.0 15.7 2.7 2 2 0 2 2 2 1 Intermediate filament protein DUF4200 PF13863.6 KDO28649.1 - 0.12 12.8 29.3 1.1 9.7 0.1 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4200) Bap31_Bap29_C PF18035.1 KDO28649.1 - 0.13 12.3 0.3 0.13 12.3 0.3 3.7 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Baculo_p24 PF05073.12 KDO28649.1 - 5.6 6.7 15.5 0.28 10.9 2.0 3.4 2 1 2 4 4 4 0 Baculovirus P24 capsid protein DUF1192 PF06698.11 KDO28649.1 - 7 6.8 10.3 1.2 9.2 3.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) EamA PF00892.20 KDO28650.1 - 6e-06 26.5 10.0 7e-06 26.3 10.0 1.1 1 0 0 1 1 1 1 EamA-like transporter family Multi_Drug_Res PF00893.19 KDO28650.1 - 0.017 15.7 2.8 0.037 14.7 2.0 1.9 1 1 1 2 2 2 0 Small Multidrug Resistance protein Neurensin PF14927.6 KDO28650.1 - 0.33 10.6 1.8 4.3 7.0 1.6 2.3 1 1 0 1 1 1 0 Neurensin EamA PF00892.20 KDO28651.1 - 1.5e-13 51.1 42.6 2.7e-10 40.6 20.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 KDO28652.1 - 3.5e-21 75.8 41.9 6.9e-15 55.4 15.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 KDO28653.1 - 2.7e-13 50.2 31.1 1.5e-06 28.4 12.2 3.1 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO28653.1 - 0.066 12.5 7.2 0.072 12.4 5.2 2.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family Ank_2 PF12796.7 KDO28654.1 - 1.9e-23 82.8 4.9 1.7e-07 31.7 0.3 6.1 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28654.1 - 2.5e-19 69.4 15.2 4.9e-05 23.8 0.1 8.0 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28654.1 - 5e-16 58.5 12.3 0.15 12.4 0.1 9.4 5 2 5 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28654.1 - 7.9e-12 44.3 9.4 4.2 8.3 0.0 10.3 10 1 1 11 11 11 2 Ankyrin repeat Ank PF00023.30 KDO28654.1 - 0.0055 17.1 6.9 56 4.4 0.7 7.3 4 2 0 4 4 4 0 Ankyrin repeat Acetyltransf_7 PF13508.7 KDO28655.1 - 7.4e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO28655.1 - 0.00015 21.7 0.0 0.00038 20.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO28655.1 - 0.0003 20.7 0.0 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KDO28655.1 - 0.00083 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KDO28655.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO28655.1 - 0.0029 17.7 0.0 0.0055 16.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO28655.1 - 0.11 13.1 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EamA PF00892.20 KDO28656.1 - 1.8e-15 57.3 29.7 4.9e-11 43.0 11.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 KDO28657.1 - 0.0064 17.1 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28657.1 - 0.018 15.3 0.0 0.13 12.6 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28657.1 - 0.018 15.6 0.0 2.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HrpE PF06188.12 KDO28658.1 - 0.083 12.8 0.3 0.18 11.6 0.1 1.6 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E Ank_4 PF13637.6 KDO28659.1 - 2e-14 53.7 0.8 1.5e-07 31.8 0.2 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28659.1 - 2.7e-12 47.1 0.0 5.1e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28659.1 - 7.6e-12 45.2 1.7 7.1e-05 23.0 0.0 4.9 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28659.1 - 2.6e-06 27.3 4.2 0.18 12.5 0.0 5.3 5 2 1 6 6 6 2 Ankyrin repeat Ank PF00023.30 KDO28659.1 - 6e-06 26.5 0.1 0.15 12.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO28660.1 - 6.1e-28 97.2 0.5 2.2e-09 37.8 0.2 4.7 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28660.1 - 1.4e-20 73.4 3.2 1.5e-05 25.4 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28660.1 - 1.2e-17 63.7 8.4 0.0041 17.4 0.0 8.6 3 2 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28660.1 - 6.9e-15 53.7 4.0 2.2 9.1 0.0 9.6 8 1 2 10 10 10 3 Ankyrin repeat Ank PF00023.30 KDO28660.1 - 5.1e-12 45.7 0.3 0.077 13.5 0.0 7.6 4 2 2 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KDO28661.1 - 7.1e-24 84.2 5.3 1.6e-05 25.4 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28661.1 - 5.5e-18 64.8 13.5 0.035 14.4 0.1 9.7 4 3 7 11 11 11 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28661.1 - 1.1e-15 57.8 13.3 0.0031 18.1 0.1 7.8 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28661.1 - 7.4e-08 32.1 9.1 4.1 8.3 0.1 9.1 10 1 1 11 11 11 1 Ankyrin repeat Ank PF00023.30 KDO28661.1 - 2.5e-06 27.7 10.6 2.4 8.8 0.6 8.6 7 2 0 7 7 7 1 Ankyrin repeat Ank_2 PF12796.7 KDO28662.1 - 6.1e-26 90.8 7.7 1.2e-07 32.2 0.1 6.5 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28662.1 - 2.8e-18 66.0 18.2 9.5e-06 26.1 0.1 8.7 5 2 5 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28662.1 - 1e-16 60.8 22.7 0.019 15.3 0.2 11.4 4 3 6 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO28662.1 - 6e-09 36.0 8.0 0.19 12.2 0.0 8.6 6 3 1 7 7 7 2 Ankyrin repeat Ank_3 PF13606.6 KDO28662.1 - 3.3e-07 30.1 11.3 0.28 11.9 0.0 10.6 13 0 0 13 13 13 1 Ankyrin repeat DUF3088 PF11287.8 KDO28662.1 - 0.04 13.7 0.1 0.16 11.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3088) Ank_2 PF12796.7 KDO28663.1 - 3.1e-22 78.9 9.5 3.6e-06 27.5 0.0 5.3 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28663.1 - 3.3e-17 62.6 11.7 0.0027 18.2 0.1 6.9 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28663.1 - 1.6e-13 50.6 19.9 0.088 13.2 0.0 9.8 4 3 7 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28663.1 - 3.6e-11 42.2 15.7 5.3 7.9 0.0 10.0 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 KDO28663.1 - 0.032 14.7 12.6 16 6.2 1.1 6.6 5 2 0 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 KDO28663.1 - 0.27 11.8 0.8 2.1e+02 2.5 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) zf-RVT PF13966.6 KDO28664.1 - 0.00072 20.2 0.3 0.0024 18.5 0.2 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Ank_5 PF13857.6 KDO28664.1 - 0.027 14.8 1.3 9.7 6.7 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28664.1 - 0.14 12.8 0.0 0.59 10.8 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KDO28665.1 - 1.9e-16 60.4 4.0 1.4e-05 25.6 0.2 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28665.1 - 6.6e-12 45.7 6.1 7.1e-05 23.3 0.1 6.5 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28665.1 - 3.4e-09 36.8 9.7 0.027 14.8 0.0 6.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28665.1 - 3.2e-07 30.1 3.2 2.7 8.9 0.0 7.3 6 2 3 9 9 9 1 Ankyrin repeat Ank PF00023.30 KDO28665.1 - 1.1e-05 25.6 5.8 3 8.4 0.0 6.4 6 2 1 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 KDO28665.1 - 0.11 12.5 0.1 31 4.6 0.0 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF3447) EamA PF00892.20 KDO28667.1 - 4e-10 40.0 32.4 4.7e-06 26.8 11.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 KDO28668.1 - 6.4e-26 90.8 3.7 1.4e-07 32.0 0.1 5.4 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28668.1 - 1.6e-17 63.6 5.6 0.0078 16.8 0.1 8.7 8 1 2 10 10 10 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28668.1 - 1.7e-16 60.0 11.8 0.0012 19.2 0.1 9.4 5 3 6 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28668.1 - 3.5e-08 33.1 12.1 7.1 7.6 0.0 10.2 9 2 2 11 11 11 1 Ankyrin repeat Ank PF00023.30 KDO28668.1 - 8.3e-06 26.0 1.9 2.1 8.9 0.1 5.9 4 2 0 4 4 4 2 Ankyrin repeat TPH PF13868.6 KDO28669.1 - 1.1 7.8 51.5 46 2.4 51.5 2.3 1 1 0 1 1 1 0 Trichohyalin-plectin-homology domain Ank_4 PF13637.6 KDO28670.1 - 8e-12 45.4 4.6 2.8e-07 30.9 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28670.1 - 3.3e-11 43.6 4.2 1e-05 26.0 0.3 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO28670.1 - 0.00016 21.9 2.1 2.8 8.8 0.1 4.3 2 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KDO28670.1 - 0.00051 20.3 1.6 2.1 8.8 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28671.1 - 2.2e-11 44.2 3.4 9.4e-06 26.1 0.2 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28671.1 - 3.5e-09 37.0 2.0 8.1e-07 29.5 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28671.1 - 0.0001 22.5 3.3 0.036 14.4 0.1 3.5 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28671.1 - 0.06 13.9 2.7 3.2 8.6 0.0 3.7 4 1 1 5 5 5 0 Ankyrin repeat Ank PF00023.30 KDO28671.1 - 0.26 11.8 2.4 3.5 8.2 1.1 3.0 1 1 1 2 2 2 0 Ankyrin repeat PCI PF01399.27 KDO28672.1 - 7.9e-14 52.0 0.0 1.6e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ank_2 PF12796.7 KDO28673.1 - 4.9e-13 49.5 1.5 2.2e-10 41.0 0.4 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28673.1 - 2.6e-10 40.4 7.9 0.042 14.2 0.2 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28673.1 - 7.1e-09 36.0 2.8 0.00069 20.1 0.3 3.6 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28673.1 - 2e-07 30.7 0.1 1.5 9.6 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO28673.1 - 0.022 15.2 4.5 41 4.8 0.2 4.7 2 1 2 4 4 4 0 Ankyrin repeat cNMP_binding PF00027.29 KDO28674.1 - 6e-39 132.0 0.1 6.3e-19 67.8 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EF-hand_14 PF17959.1 KDO28674.1 - 0.09 13.1 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain DNA_pol_phi PF04931.13 KDO28674.1 - 6.6 4.7 6.9 9.4 4.2 6.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tubulin PF00091.25 KDO28676.1 - 1.2e-35 123.5 0.4 2e-35 122.8 0.4 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KDO28676.1 - 2.3e-29 101.5 0.3 5.2e-29 100.4 0.3 1.6 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 KDO28676.1 - 8.8 5.4 7.2 6 5.9 0.0 2.6 2 1 1 3 3 3 0 Tubulin like EamA PF00892.20 KDO28677.1 - 9e-22 77.7 40.5 3.1e-11 43.6 15.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Transport_MerF PF11431.8 KDO28677.1 - 2.6 8.0 8.3 2.6 8.0 1.0 3.4 3 0 0 3 3 3 0 Membrane transport protein MerF EamA PF00892.20 KDO28678.1 - 9.7e-24 84.1 35.1 1.3e-12 48.0 12.9 2.6 2 1 1 3 3 3 3 EamA-like transporter family Pkinase_Tyr PF07714.17 KDO28679.1 - 5.9e-40 137.2 0.0 7.5e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28679.1 - 1.4e-37 129.5 0.0 1.9e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28680.1 - 9.1e-41 139.8 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28680.1 - 9.9e-39 133.3 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain fn3_2 PF16893.5 KDO28680.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Pkinase_Tyr PF07714.17 KDO28681.1 - 8.4e-34 117.0 0.0 1.1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28681.1 - 5.6e-33 114.4 0.0 7.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Thioredoxin PF00085.20 KDO28684.1 - 3.6e-22 78.3 0.2 1.2e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin PUB PF09409.10 KDO28684.1 - 1e-14 54.2 0.0 2.4e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 PUB domain UBA PF00627.31 KDO28684.1 - 9.8e-07 28.6 0.1 2.2e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Thioredoxin_2 PF13098.6 KDO28684.1 - 4.1e-06 27.2 1.1 2.3e-05 24.8 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO28684.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO28684.1 - 0.0091 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UIM PF02809.20 KDO28684.1 - 0.036 14.0 6.1 0.14 12.1 6.1 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredoxin_9 PF14595.6 KDO28684.1 - 0.046 13.5 0.0 0.046 13.5 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin IBD PF10416.9 KDO28684.1 - 0.11 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD AhpC-TSA PF00578.21 KDO28684.1 - 0.14 12.1 0.1 0.73 9.8 0.0 2.1 2 1 1 3 3 3 0 AhpC/TSA family OST3_OST6 PF04756.13 KDO28684.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family VPS38 PF17649.1 KDO28684.1 - 0.93 8.3 3.4 1.3 7.8 3.4 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 GCN5L1 PF06320.13 KDO28685.1 - 4.7e-10 39.6 4.0 9.2e-10 38.7 4.0 1.4 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) LOH1CR12 PF10158.9 KDO28685.1 - 0.47 10.5 2.5 0.81 9.7 2.5 1.3 1 0 0 1 1 1 0 Tumour suppressor protein PDZ_2 PF13180.6 KDO28686.1 - 2.1e-07 31.2 0.2 8.6e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KDO28686.1 - 1.5e-06 28.5 0.1 3.7e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO28686.1 - 6.5e-06 25.9 0.2 1.9e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 PDZ domain Annexin PF00191.20 KDO28688.1 - 0.00014 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Annexin DUF4381 PF14316.6 KDO28689.1 - 2.2 8.5 6.1 0.43 10.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Annexin PF00191.20 KDO28690.1 - 1.2e-57 191.9 0.1 2.1e-13 50.1 0.1 4.2 4 0 0 4 4 4 4 Annexin Annexin PF00191.20 KDO28691.1 - 1.6e-29 101.8 0.0 5e-14 52.1 0.1 2.2 2 0 0 2 2 2 2 Annexin Annexin PF00191.20 KDO28694.1 - 3.2e-52 174.5 0.2 5.5e-13 48.8 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF3924 PF13062.6 KDO28694.1 - 0.15 12.0 0.1 25 4.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) WD40 PF00400.32 KDO28695.1 - 7.3e-12 45.6 9.7 0.00019 22.1 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28695.1 - 2.3e-06 27.8 0.0 0.064 13.6 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3717 PF12512.8 KDO28695.1 - 0.0023 17.8 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3717) AMPK1_CBM PF16561.5 KDO28695.1 - 0.16 12.2 1.3 0.6 10.4 0.1 2.4 3 0 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase ABC2_membrane PF01061.24 KDO28696.1 - 1.2e-34 119.6 23.4 1.7e-34 119.1 23.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO28696.1 - 1.9e-26 93.2 0.0 2.6e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO28696.1 - 4.6e-07 29.9 0.0 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO28696.1 - 5.4e-05 23.2 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KDO28696.1 - 0.00076 19.9 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO28696.1 - 0.0029 17.3 0.1 0.0054 16.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KDO28696.1 - 0.0042 16.5 0.0 0.91 8.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KDO28696.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 KDO28696.1 - 0.017 14.3 18.9 0.024 13.7 18.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.6 KDO28696.1 - 0.047 13.3 0.2 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KDO28696.1 - 0.052 13.8 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO28696.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KDO28696.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase AAA_35 PF14516.6 KDO28696.1 - 0.19 10.5 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.23 KDO28696.1 - 0.2 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-CCCH PF00642.24 KDO28697.1 - 4.8 7.2 6.1 0.3 11.0 0.4 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CTP_transf_1 PF01148.20 KDO28699.1 - 5.1e-65 219.9 19.8 1e-64 218.9 19.8 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family DUF5353 PF17304.2 KDO28699.1 - 0.047 13.4 0.7 0.46 10.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5353) Lysyl_oxidase PF01186.17 KDO28699.1 - 0.28 10.8 1.8 0.5 10.0 0.6 1.9 2 0 0 2 2 2 0 Lysyl oxidase bZIP_1 PF00170.21 KDO28700.1 - 1.2e-11 44.5 11.3 2.1e-11 43.8 11.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO28700.1 - 2.8e-06 27.3 7.3 2.8e-06 27.3 7.3 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KDO28700.1 - 1.1e-05 25.8 7.3 2e-05 25.1 7.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor YabA PF06156.13 KDO28700.1 - 0.00016 22.3 0.0 0.00031 21.3 0.0 1.4 1 0 0 1 1 1 1 Initiation control protein YabA TSC22 PF01166.18 KDO28700.1 - 0.0015 18.8 0.3 0.037 14.3 0.1 2.3 1 1 1 2 2 2 2 TSC-22/dip/bun family HALZ PF02183.18 KDO28700.1 - 0.0018 18.5 4.0 0.042 14.1 0.3 2.2 1 1 1 2 2 2 2 Homeobox associated leucine zipper CASP_C PF08172.12 KDO28700.1 - 0.0033 16.8 0.2 0.0033 16.8 0.2 1.5 2 0 0 2 2 2 1 CASP C terminal Macoilin PF09726.9 KDO28700.1 - 0.0044 15.7 0.6 0.0061 15.2 0.6 1.1 1 0 0 1 1 1 1 Macoilin family ZapB PF06005.12 KDO28700.1 - 0.014 15.8 1.9 0.02 15.3 1.3 1.6 1 1 0 1 1 1 0 Cell division protein ZapB DUF4407 PF14362.6 KDO28700.1 - 0.023 14.1 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KDO28700.1 - 0.069 12.9 3.5 0.27 11.0 0.5 2.3 1 1 1 2 2 2 0 Septum formation initiator RasGAP_C PF03836.15 KDO28700.1 - 0.084 13.0 0.7 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 RasGAP C-terminus JIP_LZII PF16471.5 KDO28700.1 - 0.11 12.6 2.6 0.29 11.3 2.6 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II EMP24_GP25L PF01105.24 KDO28700.1 - 0.12 12.3 1.0 0.22 11.4 1.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.9 KDO28700.1 - 0.14 12.2 3.7 0.23 11.5 3.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 KDO28700.1 - 0.14 12.4 5.7 0.33 11.3 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phlebovirus_NSM PF07246.11 KDO28700.1 - 0.17 11.2 1.3 0.27 10.6 1.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2205 PF10224.9 KDO28700.1 - 0.2 11.7 1.8 0.36 10.8 1.8 1.4 1 0 0 1 1 1 0 Short coiled-coil protein Mod_r PF07200.13 KDO28700.1 - 0.68 10.0 5.3 0.45 10.6 1.7 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.6 KDO28700.1 - 1.1 9.4 6.3 1.3 9.2 5.0 1.8 2 0 0 2 2 1 0 Centrosome localisation domain of PPC89 TolA_bind_tri PF16331.5 KDO28701.1 - 0.046 13.8 0.2 0.066 13.3 0.2 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation HALZ PF02183.18 KDO28701.1 - 0.079 13.2 0.8 0.15 12.3 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper 3HCDH_N PF02737.18 KDO28703.1 - 5.7e-54 182.7 0.5 5.7e-54 182.7 0.5 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KDO28703.1 - 2.1e-43 148.5 2.8 8.1e-43 146.5 2.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KDO28703.1 - 5.5e-35 119.9 0.0 4.8e-24 84.8 0.0 3.9 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KDO28703.1 - 6.6e-31 108.0 0.9 1.2e-30 107.1 0.9 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Helicase_C PF00271.31 KDO28704.1 - 7e-16 58.6 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KDO28704.1 - 2.2e-14 53.6 0.1 9.1e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) R3H PF01424.22 KDO28704.1 - 1.7e-12 47.1 0.0 1.4e-11 44.2 0.0 2.6 2 0 0 2 2 2 1 R3H domain OB_NTP_bind PF07717.16 KDO28704.1 - 8.7e-08 32.4 0.1 5.6e-07 29.8 0.1 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KDO28704.1 - 2.5e-05 24.1 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KDO28704.1 - 0.00089 18.4 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Ank_2 PF12796.7 KDO28705.1 - 6.8e-18 65.0 11.0 1.7e-07 31.7 0.3 4.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28705.1 - 2.6e-13 50.2 9.0 0.00038 21.0 0.2 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28705.1 - 4.6e-10 39.5 6.5 0.064 13.6 0.0 6.2 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28705.1 - 5.2e-07 29.5 3.8 15 6.6 0.0 7.3 5 2 2 7 7 7 2 Ankyrin repeat Ank PF00023.30 KDO28705.1 - 0.075 13.5 8.0 23 5.7 0.5 5.8 3 3 0 3 3 3 0 Ankyrin repeat CLASP_N PF12348.8 KDO28706.1 - 5.2e-31 108.0 1.6 6.9e-31 107.6 1.6 1.1 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 KDO28706.1 - 0.0016 18.8 0.4 0.24 11.8 0.2 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KDO28706.1 - 0.019 15.2 6.5 29 5.3 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Pkinase_Tyr PF07714.17 KDO28712.1 - 2.1e-51 174.7 0.0 3.8e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28712.1 - 3.7e-50 170.8 0.0 8.8e-50 169.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KDO28712.1 - 8.1e-07 28.7 10.9 0.00074 19.2 0.2 4.7 3 1 1 4 4 4 2 Leucine rich repeat Pkinase_fungal PF17667.1 KDO28712.1 - 0.00094 18.1 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_9 PF14580.6 KDO28712.1 - 0.072 12.6 2.0 0.87 9.1 0.1 3.2 3 1 0 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.7 KDO28712.1 - 0.3 11.6 17.4 0.18 12.3 0.2 5.9 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) PHD PF00628.29 KDO28713.1 - 7.6e-08 32.1 3.0 7.6e-08 32.1 3.0 4.1 3 1 1 4 4 4 1 PHD-finger Trm112p PF03966.16 KDO28713.1 - 0.091 13.3 1.7 1.6 9.3 0.0 3.1 2 0 0 2 2 2 0 Trm112p-like protein PHD_2 PF13831.6 KDO28713.1 - 2.8 7.6 21.2 3 7.5 4.9 3.6 2 1 0 2 2 2 0 PHD-finger WDCP PF15390.6 KDO28714.1 - 0.046 12.1 5.6 0.18 10.2 1.3 2.2 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family SK_channel PF03530.14 KDO28715.1 - 0.00067 19.6 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 Calcium-activated SK potassium channel Lig_chan PF00060.26 KDO28715.1 - 0.00094 19.0 1.0 0.0035 17.2 1.0 1.9 1 1 0 1 1 1 1 Ligand-gated ion channel Pkinase PF00069.25 KDO28716.1 - 1.8e-50 171.7 0.0 2.4e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28716.1 - 3.4e-47 160.9 0.0 4.3e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO28716.1 - 2.6e-05 23.2 0.0 3.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO28716.1 - 0.054 12.8 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KDO28716.1 - 0.069 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KDO28716.1 - 0.082 12.5 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_4 PF12799.7 KDO28718.1 - 0.067 13.6 1.5 0.55 10.7 0.4 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KDO28719.1 - 4.2e-51 173.8 0.0 5.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28719.1 - 3.7e-50 170.6 0.0 4.3e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO28719.1 - 0.00013 21.4 1.0 0.0002 20.8 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO28719.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO28719.1 - 0.014 15.4 1.2 0.029 14.3 0.5 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO28719.1 - 0.019 13.8 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO28719.1 - 0.062 12.2 0.1 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Roc PF08477.13 KDO28720.1 - 5.1e-10 39.6 0.0 7.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO28720.1 - 4.4e-09 36.1 0.0 6.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KDO28720.1 - 0.00033 20.1 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO28720.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Seipin PF06775.14 KDO28720.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) FH2 PF02181.23 KDO28723.1 - 8.3e-90 301.6 0.2 8.3e-90 301.6 0.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 KDO28723.1 - 1.3e-74 249.7 36.9 2.8e-12 47.3 0.1 9.0 6 1 3 9 9 9 7 Subunit CCDC53 of WASH complex Drf_FH3 PF06367.16 KDO28723.1 - 1.1e-18 67.5 6.5 7e-11 42.1 0.5 2.6 2 0 0 2 2 2 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 KDO28723.1 - 2.2e-07 30.6 0.0 2.2e-07 30.6 0.0 2.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain DUF5465 PF17553.2 KDO28723.1 - 0.012 16.0 1.2 0.035 14.6 1.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5465) Glyco_transf_8 PF01501.20 KDO28723.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 Selenoprotein_S PF06936.11 KDO28723.1 - 1.4 8.7 5.8 3.4 7.4 5.8 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) Pkinase PF00069.25 KDO28724.1 - 2.6e-50 171.3 0.0 2.9e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28724.1 - 1.9e-28 99.5 0.0 2.8e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO28724.1 - 0.00019 20.9 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO28724.1 - 0.00082 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO28724.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KDO28725.1 - 1.2e-43 149.4 0.0 1.8e-43 148.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28725.1 - 1.6e-28 99.7 0.0 2.1e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO28725.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO28725.1 - 3e-05 23.5 0.0 6.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO28725.1 - 0.0059 16.2 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 RIO1 family bZIP_1 PF00170.21 KDO28726.1 - 6e-09 35.9 15.6 1.3e-08 34.8 15.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO28726.1 - 0.0015 18.6 14.4 0.0015 18.6 14.4 2.4 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KDO28726.1 - 0.012 16.1 10.6 0.027 15.0 10.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor PKcGMP_CC PF16808.5 KDO28726.1 - 0.019 14.8 6.2 1.7 8.6 1.1 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 KDO28726.1 - 0.024 12.2 5.8 0.032 11.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5075 PF16825.5 KDO28726.1 - 0.052 13.2 0.1 0.66 9.7 0.1 2.3 2 0 0 2 2 2 0 IGP family C-type lectin domain V_ATPase_I PF01496.19 KDO28726.1 - 0.07 11.0 3.8 0.12 10.2 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 KDO28726.1 - 0.24 11.7 8.8 4.3 7.7 4.4 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF641 PF04859.12 KDO28726.1 - 0.36 11.2 8.3 0.75 10.1 8.3 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KDO28726.1 - 0.37 11.4 9.5 0.3 11.8 3.3 3.2 2 2 2 4 4 4 0 Initiation control protein YabA ATG16 PF08614.11 KDO28726.1 - 0.98 9.6 15.0 23 5.2 15.0 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FapA PF03961.13 KDO28726.1 - 1.2 7.6 7.6 1.8 7.1 7.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KDO28726.1 - 2.3 8.3 8.4 4 7.5 8.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF737 PF05300.11 KDO28726.1 - 2.8 8.2 13.2 3.4 8.0 11.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Arm PF00514.23 KDO28727.1 - 9.4e-22 76.3 17.1 8.8e-08 31.9 0.0 7.7 7 1 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO28727.1 - 1.7e-08 34.7 6.6 0.18 12.2 0.0 4.7 3 2 3 6 6 6 4 HEAT repeats RICTOR_V PF14668.6 KDO28727.1 - 5.8e-05 23.2 2.3 0.095 12.9 0.0 4.6 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 KDO28727.1 - 0.00063 19.8 3.8 44 4.7 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KDO28727.1 - 0.0013 19.2 8.4 1.2 9.7 0.1 5.0 3 2 3 6 6 6 2 HEAT-like repeat SYCP2_ARLD PF18581.1 KDO28727.1 - 0.031 14.3 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain HEAT_PBS PF03130.16 KDO28727.1 - 3.1 8.7 12.7 70 4.5 0.1 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat CPSase_L_D2 PF02786.17 KDO28729.1 - 1e-73 247.4 0.1 1.6e-73 246.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KDO28729.1 - 1.8e-44 150.8 0.3 7.8e-44 148.7 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KDO28729.1 - 1.1e-36 125.2 0.0 3e-36 123.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KDO28729.1 - 5.3e-18 64.6 1.4 1.5e-17 63.2 1.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KDO28729.1 - 3.1e-12 46.5 0.0 7e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KDO28729.1 - 7.7e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KDO28729.1 - 3.9e-05 23.8 0.0 7.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KDO28729.1 - 0.00017 21.2 0.0 0.00052 19.7 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 KDO28729.1 - 0.00046 20.9 0.0 0.019 15.6 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 KDO28729.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 KDO28729.1 - 0.0025 17.6 3.5 1.6 8.6 0.0 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_4 PF13535.6 KDO28729.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain HlyD_D23 PF16576.5 KDO28729.1 - 0.022 14.0 0.0 0.59 9.3 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 KDO28729.1 - 0.044 13.0 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 KDO28729.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein BBP1_N PF15271.6 KDO28730.1 - 0.16 12.8 0.1 0.28 12.0 0.0 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein MPC PF03650.13 KDO28732.1 - 2.3e-37 127.5 0.2 2.6e-37 127.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CRAL_TRIO PF00650.20 KDO28733.1 - 2.7e-16 59.7 0.0 4.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 KDO28733.1 - 1.9e-10 41.2 0.0 4.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 KDO28733.1 - 0.00016 21.8 0.0 0.00041 20.5 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain TetR_C_25 PF17933.1 KDO28733.1 - 0.081 13.3 0.0 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LSM PF01423.22 KDO28734.1 - 4.4e-20 71.2 0.0 4.9e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO28734.1 - 0.087 13.0 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain RNase_P_Rpp14 PF01900.19 KDO28736.1 - 5.5e-21 74.8 0.1 7.3e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF1749 PF08538.10 KDO28736.1 - 0.1 11.7 0.1 2.2 7.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) DUF1810 PF08837.11 KDO28736.1 - 0.11 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) HTH_41 PF14502.6 KDO28736.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SAP18 PF06487.12 KDO28737.1 - 1.3e-26 93.4 0.0 2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glycos_transf_1 PF00534.20 KDO28739.1 - 2.7e-19 69.4 0.0 5.2e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO28739.1 - 4.6e-16 59.5 0.2 1e-15 58.3 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO28739.1 - 1.5e-06 28.5 0.0 4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arm PF00514.23 KDO28740.1 - 0.00057 19.8 0.0 9 6.5 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Fes1 PF08609.10 KDO28740.1 - 0.00082 20.2 2.2 0.0082 17.0 1.5 2.7 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 KDO28740.1 - 0.0019 18.3 2.4 2.1 8.8 0.1 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KDO28740.1 - 0.0051 17.2 0.4 0.022 15.1 0.0 2.3 2 1 0 2 2 2 1 HEAT repeats DUF3361 PF11841.8 KDO28740.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Mg_trans_NIPA PF05653.14 KDO28741.1 - 4.7e-41 140.8 20.0 4.3e-40 137.7 20.0 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KDO28741.1 - 6.8e-07 29.5 1.1 6.8e-07 29.5 1.1 3.0 2 1 0 2 2 2 1 EamA-like transporter family TMEM234 PF10639.9 KDO28741.1 - 0.04 13.9 8.7 0.055 13.5 0.0 3.2 3 0 0 3 3 3 0 Putative transmembrane family 234 PACT_coil_coil PF10495.9 KDO28741.1 - 0.094 13.3 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein AWPM-19 PF05512.11 KDO28741.1 - 0.14 12.4 8.6 0.14 12.4 6.8 2.0 1 1 0 1 1 1 0 AWPM-19-like family SAICAR_synt PF01259.18 KDO28742.1 - 4.9e-75 252.4 0.0 6.9e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Mito_carr PF00153.27 KDO28743.1 - 1.2e-65 217.4 0.6 1.1e-21 76.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KDO28744.1 - 1.7e-60 201.0 0.7 4.3e-19 68.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PQQ_2 PF13360.6 KDO28745.1 - 0.00046 19.8 0.5 0.0016 18.1 0.5 1.9 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 KDO28745.1 - 0.35 11.4 2.6 1.5 9.4 0.5 2.9 2 0 0 2 2 2 0 PQQ-like domain TAF6_C PF07571.13 KDO28746.1 - 2.4e-28 98.3 0.0 4.5e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KDO28746.1 - 9.7e-06 25.7 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Med18 PF09637.10 KDO28747.1 - 2.4e-09 37.4 0.0 2e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Med18 protein Metallophos PF00149.28 KDO28748.1 - 3.2e-11 44.1 0.0 9.3e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 KDO28749.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 KDO28750.1 - 1.4e-15 57.6 10.9 6.2e-07 29.9 0.4 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO28750.1 - 7.8e-15 55.0 20.8 7.6e-06 26.4 0.5 6.7 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO28750.1 - 5.8e-12 45.6 19.7 0.023 15.0 0.1 6.9 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28750.1 - 2.2e-05 24.5 10.0 9.2 7.2 0.1 7.6 7 1 2 9 9 9 1 Ankyrin repeat Ank PF00023.30 KDO28750.1 - 0.0013 19.0 7.4 52 4.5 0.1 7.0 2 2 2 4 4 4 0 Ankyrin repeat DUF3322 PF11795.8 KDO28750.1 - 0.068 13.2 1.0 3.6 7.6 0.0 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) YidD PF01809.18 KDO28750.1 - 0.13 12.1 0.3 4.5 7.2 0.0 2.9 2 1 1 3 3 3 0 Putative membrane protein insertion efficiency factor VPS9 PF02204.18 KDO28751.1 - 1.1e-26 93.0 0.0 2.2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KDO28751.1 - 0.12 12.7 0.1 0.62 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5601) AhpC-TSA PF00578.21 KDO28754.1 - 6.8e-26 90.6 0.0 9e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO28754.1 - 1.1e-10 41.4 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KDO28754.1 - 1.2e-08 34.7 0.3 2.7e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin zf-HIT PF04438.16 KDO28755.1 - 7.3e-06 25.8 11.6 1.3e-05 24.9 11.6 1.4 1 0 0 1 1 1 1 HIT zinc finger GFP PF01353.22 KDO28755.1 - 0.00057 19.4 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Green fluorescent protein PolC_DP2 PF03833.13 KDO28755.1 - 1.2 6.9 3.4 1.4 6.7 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nup54 PF13874.6 KDO28756.1 - 7.8e-37 126.5 3.4 1.3e-36 125.8 3.4 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KDO28756.1 - 0.0032 18.3 104.5 3.6 8.5 42.0 3.7 1 1 2 3 3 3 3 Nucleoporin FG repeat region NUC153 PF08159.12 KDO28758.1 - 2.9e-11 43.0 8.8 1.8e-07 30.8 0.8 3.7 3 0 0 3 3 3 3 NUC153 domain Ribosomal_S28e PF01200.18 KDO28759.1 - 9.6e-32 108.8 0.6 1.1e-31 108.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Rgp1 PF08737.10 KDO28760.1 - 6.1e-13 48.7 0.1 8.9e-08 31.7 0.0 2.3 2 1 0 2 2 2 2 Rgp1 Arrestin_C PF02752.22 KDO28760.1 - 9.5e-05 22.9 0.0 0.17 12.3 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PPR PF01535.20 KDO28762.1 - 2.4e-19 68.1 0.0 0.0047 17.1 0.0 8.0 8 0 0 8 8 8 3 PPR repeat PPR_2 PF13041.6 KDO28762.1 - 5.6e-19 68.1 0.6 4e-06 26.9 0.0 6.5 4 2 3 7 7 7 2 PPR repeat family PPR_3 PF13812.6 KDO28762.1 - 3.1e-12 46.4 0.0 2.7e-05 24.2 0.0 4.6 3 2 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KDO28762.1 - 1.7e-10 40.6 2.4 4.2e-05 23.0 0.1 3.2 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KDO28762.1 - 2e-08 34.6 4.6 0.00015 22.2 0.1 4.4 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28762.1 - 7.7e-05 23.2 4.1 2.4 9.2 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28762.1 - 0.0001 22.2 2.8 1.7 8.9 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO28762.1 - 0.00021 21.5 9.6 0.35 11.2 0.2 5.5 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO28762.1 - 0.0005 19.8 9.6 0.11 12.4 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO28762.1 - 0.00051 20.2 10.4 0.76 10.1 0.3 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KDO28762.1 - 0.00071 20.2 10.0 0.15 12.7 0.1 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28762.1 - 0.0013 18.7 3.0 1.1 9.4 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR_1 PF12854.7 KDO28762.1 - 0.0032 17.1 0.0 7.5 6.3 0.0 4.8 5 0 0 5 5 5 1 PPR repeat TPR_6 PF13174.6 KDO28762.1 - 0.016 15.8 3.9 34 5.4 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO28762.1 - 0.033 14.4 1.2 18 5.8 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO28762.1 - 0.07 13.8 0.1 44 5.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KDO28762.1 - 0.13 12.3 8.3 1.2 9.2 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.20 KDO28762.1 - 0.19 11.6 1.4 1.4 8.8 0.2 3.0 2 2 0 2 2 2 0 Region in Clathrin and VPS TPR_11 PF13414.6 KDO28762.1 - 2.2 8.0 6.3 60 3.4 0.0 4.6 5 0 0 5 5 5 0 TPR repeat DUF4611 PF15387.6 KDO28765.1 - 0.046 13.9 0.8 0.093 13.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 KDO28765.1 - 0.047 13.4 3.0 0.072 12.8 3.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.26 KDO28766.1 - 1.8e-23 82.1 1.3 2.6e-23 81.6 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PTSIIB_sorb PF03830.15 KDO28766.1 - 0.046 13.9 0.2 0.063 13.5 0.2 1.2 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Mlf1IP PF10248.9 KDO28766.1 - 0.13 12.2 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Cyclin_N PF00134.23 KDO28767.1 - 2.3e-22 79.1 0.8 3.9e-22 78.3 0.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO28767.1 - 3.3e-09 36.9 0.3 7.7e-09 35.7 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain zf-C3HC4_3 PF13920.6 KDO28769.1 - 6.3e-11 42.0 7.9 6.3e-11 42.0 7.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO28769.1 - 0.00017 21.4 8.4 0.00017 21.4 8.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO28769.1 - 0.0053 17.1 8.7 0.0053 17.1 8.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO28769.1 - 0.089 12.6 8.8 0.22 11.4 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 KDO28769.1 - 0.11 12.8 0.0 0.53 10.6 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2442 PF10387.9 KDO28769.1 - 0.16 12.3 0.0 0.79 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Spc7 PF08317.11 KDO28769.1 - 0.22 10.4 13.1 0.44 9.4 13.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KDO28769.1 - 0.49 10.5 8.6 0.29 11.2 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 KDO28769.1 - 0.81 9.4 7.0 7.4 6.3 0.5 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain zf-RING_5 PF14634.6 KDO28769.1 - 2.4 8.2 13.9 0.31 11.0 9.6 1.8 2 0 0 2 2 1 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 KDO28769.1 - 5.4 7.1 7.5 9.3 6.4 5.2 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF2205 PF10224.9 KDO28769.1 - 7 6.7 6.4 1.5 8.9 0.2 2.4 2 0 0 2 2 2 0 Short coiled-coil protein DUF966 PF06136.13 KDO28769.1 - 9.9 5.8 9.8 15 5.2 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Aminotran_1_2 PF00155.21 KDO28770.1 - 4.1e-38 131.5 0.0 5.9e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DapB_C PF05173.14 KDO28770.1 - 1e-27 96.6 0.0 2.3e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Aminotran_MocR PF12897.7 KDO28770.1 - 5.1e-10 38.7 0.0 4.8e-09 35.5 0.0 2.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DapB_N PF01113.20 KDO28770.1 - 2e-08 34.4 0.0 1.4e-06 28.4 0.0 2.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Beta_elim_lyase PF01212.21 KDO28770.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase CRAL_TRIO PF00650.20 KDO28771.1 - 2.3e-26 92.4 0.0 2.8e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Nif11 PF07862.11 KDO28771.1 - 0.13 12.6 0.4 12 6.3 0.0 3.5 4 1 0 4 4 4 0 Nif11 domain HEAT_2 PF13646.6 KDO28772.1 - 3.3e-32 110.7 4.0 7.7e-14 51.8 0.6 3.1 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 KDO28772.1 - 4e-22 76.6 0.0 0.00029 21.2 0.0 6.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KDO28772.1 - 3.1e-06 26.9 0.4 1.4 9.4 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 KDO28772.1 - 0.04 14.0 0.1 4.5 7.5 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KDO28772.1 - 0.11 13.1 3.5 27 5.4 0.0 3.7 2 2 2 4 4 4 0 HEAT-like repeat Cpn10 PF00166.21 KDO28773.1 - 3e-29 100.9 0.0 3.3e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ANAPC10 PF03256.16 KDO28774.1 - 4.3e-66 222.1 0.0 4.6e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KDO28774.1 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 KDO28774.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 PITH domain PH PF00169.29 KDO28775.1 - 0.0013 19.2 0.0 0.0036 17.8 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO28775.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Helicase_C_2 PF13307.6 KDO28776.1 - 1.1e-53 182.0 0.1 6.4e-53 179.4 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 KDO28776.1 - 8.6e-49 165.5 0.3 1.4e-48 164.8 0.3 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KDO28776.1 - 0.0011 19.0 0.2 0.0038 17.2 0.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CoA_transf_3 PF02515.17 KDO28776.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 CoA-transferase family III PhoH PF02562.16 KDO28776.1 - 0.16 11.4 0.1 1.3 8.4 0.1 2.3 1 1 0 1 1 1 0 PhoH-like protein RtcB PF01139.17 KDO28777.1 - 9.8e-54 183.1 0.0 1.2e-53 182.8 0.0 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB GrpE PF01025.19 KDO28778.1 - 1.7e-46 158.0 0.0 2.1e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 GrpE DivIC PF04977.15 KDO28778.1 - 0.04 13.7 0.6 0.17 11.6 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator Dynein_light PF01221.18 KDO28779.1 - 9.1e-25 86.8 1.6 1e-24 86.7 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 KDO28779.1 - 0.037 13.9 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) TPR_1 PF00515.28 KDO28780.1 - 1.9e-22 78.1 0.7 3.4e-06 26.6 0.0 4.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28780.1 - 1.2e-18 65.6 0.2 6.3e-06 25.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO28780.1 - 1.9e-14 53.0 0.4 9.5e-08 31.6 0.0 3.8 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 KDO28780.1 - 4.9e-10 38.8 0.0 0.1 12.9 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO28780.1 - 3.4e-08 34.0 1.3 0.0004 21.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO28780.1 - 4.6e-08 33.1 0.2 1e-05 25.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO28780.1 - 1.7e-07 31.1 0.0 0.011 16.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28780.1 - 7.8e-07 28.7 0.1 0.045 13.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28780.1 - 2.8e-05 24.6 4.7 1.7 9.7 0.1 4.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO28780.1 - 5.2e-05 23.5 0.4 0.76 10.1 0.0 3.5 1 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO28780.1 - 9.4e-05 22.4 0.1 0.25 11.4 0.0 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.15 KDO28780.1 - 0.0017 18.4 0.1 0.41 10.7 0.1 2.4 2 0 0 2 2 2 1 MAS20 protein import receptor TPR_19 PF14559.6 KDO28780.1 - 0.0044 17.5 9.4 1.5 9.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 KDO28780.1 - 0.01 15.6 4.2 0.01 15.6 4.2 2.6 2 1 0 2 2 1 0 Cwf15/Cwc15 cell cycle control protein DUF4407 PF14362.6 KDO28780.1 - 1.2 8.4 4.9 2 7.7 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_III_AB PF09548.10 KDO28780.1 - 9 6.4 6.0 0.51 10.4 0.5 1.7 2 0 0 2 2 1 0 Stage III sporulation protein AB (spore_III_AB) Mito_carr PF00153.27 KDO28781.1 - 1.4e-43 146.8 0.3 7.8e-21 73.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Ricin_B_lectin PF00652.22 KDO28782.1 - 1.2e-20 74.1 21.2 5.4e-09 36.4 1.1 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO28782.1 - 5.1e-08 33.5 5.2 0.0047 17.6 0.1 3.6 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO28782.1 - 0.0064 16.1 8.2 0.068 12.8 0.7 3.0 1 1 0 3 3 3 2 Cytolethal distending toxin A/C domain ET PF01684.16 KDO28782.1 - 0.021 15.1 3.1 0.29 11.5 0.1 2.7 2 1 0 2 2 2 0 ET module 5_nucleotid_C PF02872.18 KDO28783.1 - 1.1e-12 48.5 0.0 2.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KDO28783.1 - 1.4e-10 42.0 0.0 3.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KDO28784.1 - 2.6e-15 57.0 0.0 5.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KDO28784.1 - 3.4e-08 34.2 0.0 6.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA-synt_2 PF00152.20 KDO28785.1 - 1.2e-91 307.1 0.0 3.2e-63 213.7 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KDO28785.1 - 0.068 12.6 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Sugarporin_N PF11471.8 KDO28785.1 - 2.4 8.2 4.4 30 4.7 0.4 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CKS PF01111.19 KDO28786.1 - 2.4e-35 120.6 0.7 3.1e-35 120.3 0.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ank_4 PF13637.6 KDO28787.1 - 6.7e-25 87.1 15.1 2e-06 28.2 0.1 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28787.1 - 3.8e-24 85.1 9.9 3.9e-07 30.6 0.4 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28787.1 - 4.1e-15 55.6 17.5 0.056 13.8 0.0 8.4 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28787.1 - 1.1e-11 43.8 10.4 2 9.3 0.0 8.9 9 0 0 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 KDO28787.1 - 2.3e-06 27.4 0.1 13 5.8 0.0 6.7 2 1 6 8 8 8 1 Domain of unknown function (DUF5049) Methyltransf_32 PF13679.6 KDO28787.1 - 0.0026 17.8 1.0 0.88 9.5 0.0 2.9 1 1 2 3 3 3 2 Methyltransferase domain HTH_Tnp_Tc5 PF03221.16 KDO28788.1 - 5.8e-07 29.5 0.0 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KDO28788.1 - 0.00056 19.5 0.4 0.0013 18.4 0.4 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 KDO28788.1 - 0.0015 18.0 0.4 0.0038 16.7 0.4 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 KDO28788.1 - 0.11 12.5 0.1 0.35 10.9 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix LSM PF01423.22 KDO28789.1 - 3.1e-18 65.2 0.3 6e-18 64.3 0.3 1.5 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 KDO28789.1 - 0.052 13.2 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Hfq protein NatB_MDM20 PF09797.9 KDO28790.1 - 1.3e-65 221.9 0.2 2e-65 221.2 0.2 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.17 KDO28790.1 - 0.0012 19.3 1.4 0.079 13.4 0.1 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KDO28790.1 - 0.0016 18.6 0.4 0.093 13.0 0.1 3.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 EH_Signature PF15611.6 KDO28790.1 - 0.074 12.5 0.4 0.18 11.2 0.4 1.7 1 1 0 1 1 1 0 EH_Signature domain OmdA PF13376.6 KDO28790.1 - 0.13 12.3 2.1 5.4 7.1 0.1 3.8 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated TPR_6 PF13174.6 KDO28790.1 - 7 7.5 7.1 65 4.5 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat GATase_4 PF13230.6 KDO28791.1 - 1.2e-12 47.3 0.1 6.2e-10 38.4 0.0 2.7 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KDO28791.1 - 7.2e-11 42.4 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAC PF01849.18 KDO28792.1 - 8.9e-23 80.0 0.1 1.4e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 NAC domain DUF4611 PF15387.6 KDO28792.1 - 0.035 14.3 0.2 0.061 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ThiF PF00899.21 KDO28793.1 - 4.2e-29 101.6 0.0 5.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KDO28793.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KDO28793.1 - 0.0082 16.6 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding eIF-5_eIF-2B PF01873.17 KDO28794.1 - 2.7e-37 127.2 0.1 3.1e-37 127.0 0.1 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 KDO28794.1 - 0.0073 16.7 0.8 0.016 15.6 0.5 1.9 2 1 0 2 2 2 1 Restriction alleviation protein Lar SHS2_Rpb7-N PF03876.17 KDO28795.1 - 3.4e-09 36.9 0.1 1.7e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 KDO28795.1 - 4.4e-09 37.0 2.4 2.3e-06 28.2 0.0 2.6 2 1 1 3 3 3 2 RPA43 OB domain in RNA Pol I Nitroreductase PF00881.24 KDO28797.1 - 8.2e-24 84.5 0.2 1.3e-22 80.7 0.2 2.0 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KDO28797.1 - 0.0017 18.0 0.0 0.065 12.8 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase R3H PF01424.22 KDO28798.1 - 1.5e-13 50.5 0.0 5.3e-13 48.8 0.0 2.1 1 0 0 1 1 1 1 R3H domain zf-B_box PF00643.24 KDO28798.1 - 1.7e-11 44.0 17.1 8.9e-06 25.8 6.9 2.4 2 0 0 2 2 2 2 B-box zinc finger zf-CCCH PF00642.24 KDO28798.1 - 2.3e-11 43.3 14.4 2.4e-06 27.3 0.5 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO28798.1 - 2.6e-08 33.7 16.4 0.00089 19.2 2.6 3.6 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_3 PF15663.5 KDO28798.1 - 2.6e-06 27.6 0.6 2.6e-06 27.6 0.6 2.5 2 0 0 2 2 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KDO28798.1 - 2.1e-05 24.8 18.2 0.0011 19.4 1.1 3.6 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KDO28798.1 - 6.4e-05 22.7 0.4 6.4e-05 22.7 0.4 3.1 3 1 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KDO28798.1 - 0.0027 18.4 4.5 0.054 14.2 0.6 2.7 1 1 1 2 2 2 1 Torus domain zf-HIT PF04438.16 KDO28798.1 - 0.013 15.4 19.1 0.046 13.6 2.7 3.0 3 0 0 3 3 3 0 HIT zinc finger C1_4 PF07975.12 KDO28798.1 - 0.015 15.5 18.7 0.1 12.9 5.5 3.0 1 1 1 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 KDO28798.1 - 2 8.7 29.5 2.1 8.6 7.7 3.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-MYND PF01753.18 KDO28798.1 - 8.7 6.5 23.6 8.3 6.6 9.5 3.0 2 1 0 2 2 2 0 MYND finger RRM_1 PF00076.22 KDO28799.1 - 4.6e-09 36.0 0.0 5.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO28799.1 - 0.00079 19.2 0.1 0.00091 19.0 0.1 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KDO28799.1 - 0.013 15.6 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif DUF4623 PF15416.6 KDO28799.1 - 0.05 12.2 0.0 0.057 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) DUF3992 PF13157.6 KDO28799.1 - 0.081 13.7 0.5 0.12 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) DUF4523 PF15023.6 KDO28799.1 - 0.1 12.4 0.1 0.19 11.6 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) FAD_binding_3 PF01494.19 KDO28800.1 - 2.2e-19 69.9 0.1 3.2e-11 43.1 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain SE PF08491.10 KDO28800.1 - 1e-05 24.8 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KDO28800.1 - 0.00022 20.9 0.2 0.0014 18.3 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO28800.1 - 0.00053 19.2 0.8 0.16 11.0 0.3 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KDO28800.1 - 0.00066 18.6 0.1 1.6 7.5 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.18 KDO28800.1 - 0.00096 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 KDO28800.1 - 0.0015 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO28800.1 - 0.0026 17.1 0.1 0.064 12.5 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO28800.1 - 0.024 15.2 0.0 0.057 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.29 KDO28801.1 - 5.2e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO28801.1 - 0.0039 17.6 0.9 0.015 15.7 0.9 2.0 1 0 0 1 1 1 1 AAA ATPase domain Ribosomal_60s PF00428.19 KDO28801.1 - 0.03 14.9 2.2 0.03 14.9 2.2 3.4 3 2 0 3 3 3 0 60s Acidic ribosomal protein AAA_22 PF13401.6 KDO28801.1 - 0.031 14.6 0.0 0.091 13.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KDO28801.1 - 0.071 13.1 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KDO28801.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain Herpes_Helicase PF02689.14 KDO28801.1 - 0.1 10.5 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 Helicase SRP14 PF02290.15 KDO28802.1 - 1.7e-16 60.3 0.0 2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Pertactin PF03212.14 KDO28802.1 - 0.052 13.5 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 Pertactin AARP2CN PF08142.12 KDO28803.1 - 3.7e-16 59.0 0.0 1.2e-15 57.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RIBIOP_C PF04950.12 KDO28803.1 - 4.8e-14 52.5 0.2 8.6e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal VRR_NUC PF08774.11 KDO28804.1 - 2.3e-11 43.7 0.0 5.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain FANC_SAP PF18081.1 KDO28804.1 - 0.00068 19.8 0.1 0.0027 17.8 0.1 2.1 1 0 0 1 1 1 1 Fanconi anemia-associated nuclease SAP domain TPR_1 PF00515.28 KDO28804.1 - 0.0022 17.8 0.0 0.15 11.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank_4 PF13637.6 KDO28804.1 - 0.0025 18.4 0.0 0.24 12.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_12 PF13424.6 KDO28804.1 - 0.0062 16.8 0.4 0.079 13.3 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO28804.1 - 0.012 16.1 1.1 0.032 14.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO28804.1 - 0.019 15.2 0.0 1.7 9.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28804.1 - 0.031 14.4 0.0 1.3 9.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO28804.1 - 0.035 14.0 0.4 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_6 PF00970.24 KDO28805.1 - 2.1e-21 76.1 0.0 3.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KDO28805.1 - 9.8e-19 67.3 0.0 1.8e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 KDO28805.1 - 4.3e-15 56.3 0.0 6.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KDO28805.1 - 0.0028 17.8 0.0 0.013 15.6 0.1 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Tam41_Mmp37 PF09139.11 KDO28806.1 - 2.2e-94 316.5 0.0 4.3e-94 315.6 0.0 1.4 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial T4_tail_cap PF11091.8 KDO28806.1 - 0.057 12.3 0.0 0.12 11.3 0.0 1.4 2 0 0 2 2 2 0 Tail-tube assembly protein EB1 PF03271.17 KDO28807.1 - 3e-16 59.4 1.5 8.5e-16 57.9 1.5 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KDO28807.1 - 1.7e-08 34.6 0.1 3.1e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KDO28807.1 - 0.0051 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein PNPase_C PF12111.8 KDO28807.1 - 0.025 14.0 9.3 0.025 14.0 9.3 2.2 1 1 1 2 2 2 0 Polyribonucleotide phosphorylase C terminal APG6_N PF17675.1 KDO28807.1 - 0.035 14.6 2.0 0.055 14.0 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_2 PF07716.15 KDO28807.1 - 0.041 14.0 0.5 0.089 12.9 0.5 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KDO28807.1 - 0.07 13.2 0.5 0.14 12.3 0.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF3818 PF12825.7 KDO28807.1 - 0.078 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DivIC PF04977.15 KDO28807.1 - 0.1 12.4 0.3 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator ARL2_Bind_BART PF11527.8 KDO28808.1 - 6.2e-21 74.7 5.2 7.5e-21 74.4 5.2 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART TFIIB PF00382.19 KDO28809.1 - 5.1e-21 74.5 1.8 7.6e-12 45.1 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KDO28809.1 - 9.9e-10 37.8 4.2 1.7e-09 37.1 1.0 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 KDO28809.1 - 0.00064 19.5 0.2 0.46 10.2 0.0 2.1 1 1 1 2 2 2 2 Cyclin, N-terminal domain Xol-1_N PF09108.10 KDO28809.1 - 0.031 14.1 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal Ribosomal_S27e PF01667.17 KDO28809.1 - 0.04 13.6 1.0 0.26 11.0 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 A2L_zn_ribbon PF08792.10 KDO28809.1 - 1.1 9.0 5.3 26 4.7 0.0 2.9 2 1 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 KDO28809.1 - 6 6.4 6.4 26 4.4 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Erf4 PF10256.9 KDO28810.1 - 7.6e-07 29.2 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TACC_C PF05010.14 KDO28811.1 - 0.0037 17.1 2.3 0.0052 16.6 2.3 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ISG65-75 PF11727.8 KDO28811.1 - 0.025 13.8 1.9 0.036 13.3 1.9 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein CENP-H PF05837.12 KDO28811.1 - 0.031 14.7 5.4 0.029 14.8 3.5 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ANAPC4 PF12896.7 KDO28811.1 - 0.088 12.3 0.5 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Fib_alpha PF08702.10 KDO28811.1 - 0.16 12.1 1.5 0.27 11.4 0.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2828 PF11443.8 KDO28811.1 - 0.25 9.4 4.9 0.29 9.2 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) THOC7 PF05615.13 KDO28811.1 - 0.7 10.2 8.4 0.62 10.3 6.9 1.7 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 KDO28811.1 - 1.3 8.4 7.6 1.5 8.1 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTF2 PF02136.20 KDO28812.1 - 1.2e-25 90.4 0.1 1.3e-25 90.3 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KDO28812.1 - 0.00077 19.8 0.0 0.00089 19.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KDO28812.1 - 0.08 13.6 0.0 0.096 13.3 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain ETC_C1_NDUFA5 PF04716.14 KDO28813.1 - 1.6e-17 63.0 0.0 2.4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region ALS_ss_C PF10369.9 KDO28813.1 - 0.085 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Small subunit of acetolactate synthase FATC PF02260.20 KDO28813.1 - 0.096 12.5 0.1 0.3 11.0 0.1 1.9 1 0 0 1 1 1 0 FATC domain Sas10 PF09368.10 KDO28814.1 - 1e-25 90.0 9.1 1e-25 90.0 9.1 2.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KDO28814.1 - 1.7e-11 44.6 1.3 1.3e-09 38.5 0.5 3.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family GRIP PF01465.20 KDO28815.1 - 4.8e-14 52.0 0.2 1.2e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 GRIP domain Filament PF00038.21 KDO28815.1 - 0.0042 16.7 5.0 0.0042 16.7 5.0 2.5 2 1 0 2 2 2 1 Intermediate filament protein PSII_Pbs31 PF18240.1 KDO28815.1 - 0.29 11.6 4.1 0.34 11.4 1.6 2.3 2 0 0 2 2 2 0 Photosystem II Psb31 protein GCR PF02155.15 KDO28815.1 - 0.55 9.2 3.9 0.26 10.3 1.0 1.8 2 0 0 2 2 2 0 Glucocorticoid receptor PNP_UDP_1 PF01048.20 KDO28816.1 - 9.2e-41 139.6 0.2 1.2e-40 139.2 0.2 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 KDO28817.1 - 2.2e-24 85.3 7.3 0.0001 23.0 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28817.1 - 2.8e-11 43.5 0.0 0.0092 16.3 0.0 5.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO28817.1 - 0.0011 18.0 0.3 0.51 9.2 0.1 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO28817.1 - 0.004 17.1 0.1 0.43 10.4 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KDO28817.1 - 0.028 13.1 0.1 0.6 8.7 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4246 PF14033.6 KDO28820.1 - 1.6e-17 63.8 0.0 4.9e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) UCH PF00443.29 KDO28821.1 - 1.1e-50 172.6 0.0 1.4e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO28821.1 - 1.3e-20 74.2 0.0 6.4e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Trypan_PARP PF05887.11 KDO28821.1 - 2.5 8.1 6.8 5.2 7.1 6.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNA_pol_3_Rpc31 PF11705.8 KDO28822.1 - 6.7e-05 23.3 19.8 0.052 13.8 19.8 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SpoIID PF08486.10 KDO28822.1 - 0.081 13.5 0.0 0.15 12.7 0.0 1.4 1 1 0 1 1 1 0 Stage II sporulation protein Astro_capsid_p PF12226.8 KDO28822.1 - 0.59 9.2 6.7 0.62 9.2 6.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 KDO28822.1 - 2.9 5.9 10.6 4.1 5.4 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1676 PF07898.13 KDO28823.1 - 0.086 12.9 2.8 0.18 11.8 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Lipase_bact_N PF12262.8 KDO28823.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal UCH PF00443.29 KDO28825.1 - 3.6e-71 239.7 0.2 4.6e-71 239.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO28825.1 - 9.2e-23 81.3 0.7 8.2e-22 78.2 0.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rootletin PF15035.6 KDO28826.1 - 0.00058 19.9 4.5 0.00078 19.5 4.5 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF641 PF04859.12 KDO28826.1 - 0.034 14.5 4.7 0.073 13.4 1.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ERM PF00769.19 KDO28826.1 - 0.082 12.7 11.3 0.1 12.4 11.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 KDO28826.1 - 0.11 10.4 0.9 0.14 10.0 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cwf_Cwc_15 PF04889.12 KDO28826.1 - 0.11 12.2 10.6 0.15 11.7 10.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2570 PF10828.8 KDO28826.1 - 0.15 11.9 2.9 0.25 11.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1043 PF06295.12 KDO28826.1 - 0.35 10.9 4.7 0.52 10.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) CHD5 PF04420.14 KDO28826.1 - 0.4 10.5 2.2 0.63 9.9 2.2 1.3 1 0 0 1 1 1 0 CHD5-like protein NOA36 PF06524.12 KDO28826.1 - 4 6.7 6.0 5.5 6.2 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein GPI2 PF06432.11 KDO28826.1 - 4.4 6.7 7.9 4.2 6.7 6.9 1.4 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Uds1 PF15456.6 KDO28827.1 - 0.00053 20.2 5.0 0.00092 19.4 5.0 1.3 1 0 0 1 1 1 1 Up-regulated During Septation DDE_3 PF13358.6 KDO28828.1 - 1e-11 44.8 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KDO28828.1 - 5.2e-09 35.7 0.1 1.2e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KDO28828.1 - 1.5e-05 24.8 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KDO28828.1 - 0.00033 21.2 3.4 0.029 15.0 1.1 3.2 1 1 1 2 2 2 1 Homeodomain-like domain GerE PF00196.19 KDO28828.1 - 0.0016 17.9 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_29 PF13551.6 KDO28828.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KDO28828.1 - 0.04 13.7 1.3 0.12 12.2 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KDO28828.1 - 0.29 11.4 3.9 0.36 11.1 0.1 3.0 3 1 0 4 4 4 0 Transposase RRM_1 PF00076.22 KDO28829.1 - 3.2e-12 46.1 0.5 8e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.12 KDO28830.1 - 1.4e-49 165.4 23.5 1e-10 41.9 0.4 6.8 8 0 0 8 8 8 6 Sel1 repeat Tai4 PF16695.5 KDO28830.1 - 0.05 14.1 0.7 7.1 7.2 0.1 3.4 2 2 1 4 4 4 0 Type VI secretion system (T6SS), amidase immunity protein ICMT PF04140.14 KDO28831.1 - 1.5e-28 99.0 0.1 1.5e-28 99.0 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KDO28831.1 - 8.2e-09 35.8 0.6 8.2e-09 35.8 0.6 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KDO28831.1 - 0.0034 16.9 1.0 0.0034 16.9 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) LapA_dom PF06305.11 KDO28831.1 - 0.032 14.0 5.4 0.14 12.0 2.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FAM177 PF14774.6 KDO28832.1 - 3.6e-10 40.2 0.4 5.5e-10 39.6 0.3 1.3 1 1 0 1 1 1 1 FAM177 family MDH PF02315.16 KDO28832.1 - 0.08 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit DUF4448 PF14610.6 KDO28833.1 - 0.17 11.6 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glu-tRNAGln PF02686.15 KDO28836.1 - 5.2e-10 39.5 0.1 1.1e-09 38.5 0.0 1.5 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Rossmann-like PF10727.9 KDO28836.1 - 0.1 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain Phosducin PF02114.16 KDO28837.1 - 8.7e-14 51.1 0.0 1.1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KDO28837.1 - 0.0071 16.3 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin GvpL_GvpF PF06386.11 KDO28837.1 - 0.017 15.1 0.7 0.021 14.8 0.7 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF EF-1_beta_acid PF10587.9 KDO28837.1 - 0.078 13.4 4.6 0.078 13.4 4.6 3.1 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Glu_cyclase_2 PF05096.12 KDO28838.1 - 2.7e-73 246.5 0.0 3.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase PQQ_2 PF13360.6 KDO28838.1 - 0.0027 17.3 0.1 0.0068 16.0 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain Arylesterase PF01731.20 KDO28838.1 - 0.016 15.4 0.0 0.059 13.6 0.0 1.8 2 0 0 2 2 2 0 Arylesterase RNA_polI_A34 PF08208.11 KDO28839.1 - 1.3 9.0 17.2 0.21 11.6 0.7 2.7 1 1 1 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Ribosomal_L5_C PF00673.21 KDO28840.1 - 1.8e-23 82.5 0.0 3.5e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KDO28840.1 - 1.6e-22 79.6 0.0 2.6e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 KDO28840.1 - 0.0031 17.2 0.2 0.006 16.3 0.2 1.4 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Mcl1_mid PF12341.8 KDO28841.1 - 6.1e-52 176.8 0.0 7.1e-50 170.0 0.0 2.9 3 1 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KDO28841.1 - 7.1e-08 33.0 0.1 0.11 13.4 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO28841.1 - 1.7e-05 25.0 0.0 1 9.7 0.1 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain AhpC-TSA PF00578.21 KDO28842.1 - 1.9e-24 86.0 0.0 2.4e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO28842.1 - 5.4e-17 61.9 0.2 7.3e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KDO28842.1 - 0.0066 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme TFIIB PF00382.19 KDO28843.1 - 2.2e-27 94.9 0.0 1.6e-12 47.3 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KDO28843.1 - 1.1e-20 73.8 2.7 1.1e-20 73.8 2.7 2.0 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KDO28843.1 - 1.4e-08 34.1 5.6 2.7e-08 33.2 5.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 KDO28843.1 - 0.00061 19.4 2.9 0.0012 18.5 2.9 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 COMM_domain PF07258.14 KDO28844.1 - 4.7e-10 39.4 0.0 1.1e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 COMM domain CD99L2 PF12301.8 KDO28845.1 - 0.00076 19.8 3.3 0.0018 18.6 3.3 1.6 1 1 0 1 1 1 1 CD99 antigen like protein 2 VSP PF03302.13 KDO28845.1 - 0.95 8.2 8.5 1.4 7.7 8.5 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein Sulfotransfer_1 PF00685.27 KDO28847.1 - 9e-29 100.8 0.0 1.7e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KDO28847.1 - 0.00048 20.6 0.8 0.0035 17.8 0.2 2.0 1 1 1 2 2 2 1 Sulfotransferase family Peptidase_M13_N PF05649.13 KDO28848.1 - 1.8e-76 258.3 0.0 2.2e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO28848.1 - 3.9e-67 225.8 0.0 7.6e-67 224.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 KDO28848.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 BT1 PF03092.16 KDO28849.1 - 1.5e-17 63.1 14.5 8.2e-15 54.0 1.6 2.6 2 1 1 3 3 3 2 BT1 family Ank_2 PF12796.7 KDO28850.1 - 3.8e-17 62.6 0.2 1.6e-10 41.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO28850.1 - 3e-13 49.6 3.7 5.6e-05 23.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KDO28850.1 - 3.3e-13 49.9 0.1 4.1e-08 33.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28850.1 - 3.5e-13 48.5 0.3 0.00042 20.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KDO28850.1 - 1.8e-12 47.2 2.4 0.00017 21.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Cyclase PF04199.13 KDO28851.1 - 2.2e-49 167.2 0.6 1.2e-23 83.8 0.0 2.2 2 0 0 2 2 2 2 Putative cyclase DUF836 PF05768.14 KDO28851.1 - 0.12 12.8 0.1 28 5.2 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF4588 PF15251.6 KDO28851.1 - 0.14 11.9 0.9 18 5.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4588) CS PF04969.16 KDO28852.1 - 6.3e-16 59.2 0.0 1.3e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 KDO28852.1 - 3e-13 49.5 0.0 8.4e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. BSMAP PF12280.8 KDO28852.1 - 0.57 10.4 3.5 14 5.9 0.2 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein DUF3987 PF13148.6 KDO28852.1 - 2.5 7.1 10.3 4.1 6.3 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Mitoc_mL59 PF18126.1 KDO28853.1 - 6.5e-13 49.1 5.7 1.9e-12 47.6 5.7 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Pollen_allerg_1 PF01357.21 KDO28853.1 - 0.11 12.5 1.0 0.19 11.8 1.0 1.3 1 0 0 1 1 1 0 Pollen allergen ELMO_CED12 PF04727.13 KDO28854.1 - 4e-26 92.2 0.1 8.6e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family Na_H_Exchanger PF00999.21 KDO28855.1 - 6.5e-56 189.8 41.5 7.7e-56 189.5 41.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CCDC24 PF15669.5 KDO28856.1 - 7.9e-29 101.0 0.3 2e-28 99.7 0.3 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family DUF2407_C PF13373.6 KDO28856.1 - 0.15 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain PEN-2 PF10251.9 KDO28857.1 - 5.9e-17 61.9 3.1 7.3e-17 61.6 3.1 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase LpxC PF03331.13 KDO28858.1 - 2.2e-80 270.0 0.0 2.6e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Ribosomal_S5_C PF03719.15 KDO28858.1 - 0.043 13.3 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain PIG-S PF10510.9 KDO28859.1 - 1.4e-74 251.8 0.9 2e-73 248.0 0.9 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Gal_Lectin PF02140.18 KDO28860.1 - 4.7e-97 318.5 30.8 1.1e-16 61.0 0.3 6.1 6 0 0 6 6 6 6 Galactose binding lectin domain DUF1970 PF09301.10 KDO28860.1 - 0.63 10.3 10.9 6.3 7.1 0.7 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) DUF3123 PF11321.8 KDO28860.1 - 8.1 7.2 10.5 2.3 8.9 1.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3123) PKD_channel PF08016.12 KDO28862.1 - 1.1e-22 80.3 20.6 2.9e-22 78.9 17.7 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KDO28862.1 - 6.5e-07 28.8 20.6 6.5e-07 28.8 20.6 1.7 2 0 0 2 2 2 1 Ion transport protein Lipase_3 PF01764.25 KDO28863.1 - 2.4e-30 105.3 0.1 5.6e-30 104.1 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO28863.1 - 0.0024 18.5 0.9 0.0024 18.5 0.9 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO28863.1 - 0.043 13.1 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KDO28863.1 - 0.079 12.5 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 KDO28863.1 - 0.1 12.6 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 KDO28863.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Gal_Lectin PF02140.18 KDO28864.1 - 4.2e-230 744.9 78.5 2e-16 60.2 0.9 16.1 16 0 0 16 16 16 16 Galactose binding lectin domain DUF3395 PF11875.8 KDO28864.1 - 0.32 10.9 0.1 3.2e+02 1.1 0.0 5.2 7 0 0 7 7 7 0 Domain of unknown function (DUF3395) Trypan_PARP PF05887.11 KDO28864.1 - 0.39 10.7 12.5 1.1 9.3 12.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Toxin_30 PF08117.11 KDO28864.1 - 0.55 10.5 10.2 46 4.4 0.1 7.3 6 0 0 6 6 6 0 Ptu family PPP1R26_N PF15740.5 KDO28865.1 - 0.0035 16.1 0.0 0.0045 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 26 N-terminus Agenet PF05641.12 KDO28867.1 - 1.6e-06 28.5 0.1 2.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Agenet domain Arf PF00025.21 KDO28868.1 - 1.2e-44 151.8 0.0 1.5e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KDO28868.1 - 2.4e-14 53.3 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO28868.1 - 1.8e-12 47.5 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO28868.1 - 5.2e-11 42.3 0.0 2.3e-10 40.2 0.0 1.7 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO28868.1 - 4.4e-09 36.0 0.1 6.5e-05 22.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KDO28868.1 - 9.1e-07 29.0 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO28868.1 - 0.0017 18.8 0.2 0.66 10.3 0.1 2.2 1 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO28868.1 - 0.0058 16.6 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KDO28868.1 - 0.007 15.7 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KDO28868.1 - 0.0074 15.8 0.1 0.79 9.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KDO28868.1 - 0.071 12.7 0.1 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KDO28868.1 - 0.091 13.0 0.1 0.53 10.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Metallophos PF00149.28 KDO28869.1 - 2.5e-17 64.0 1.8 3.9e-17 63.4 1.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KDO28869.1 - 1.6e-15 57.5 0.0 4.5e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KDO28869.1 - 1.6e-10 41.6 0.1 4.6e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 KDO28869.1 - 0.016 15.8 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain PhoD PF09423.10 KDO28869.1 - 0.057 12.4 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase Acetyltransf_1 PF00583.25 KDO28870.1 - 2.7e-15 56.6 0.1 3.3e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO28870.1 - 5.4e-10 39.3 0.1 6.8e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO28870.1 - 9.6e-09 35.6 0.1 1.3e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KDO28870.1 - 0.0003 21.0 0.2 0.00044 20.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KDO28870.1 - 0.0049 16.6 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KDO28870.1 - 0.0085 16.2 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO28870.1 - 0.0099 15.8 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KDO28870.1 - 0.012 15.7 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO28870.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Nudix_hydro PF18290.1 KDO28870.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain Acetyltransf_3 PF13302.7 KDO28870.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1419 PF07215.11 KDO28870.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) Met_10 PF02475.16 KDO28871.1 - 1.8e-62 210.7 0.0 2.6e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KDO28871.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KDO28871.1 - 0.0013 19.4 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 KDO28871.1 - 0.0022 17.2 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 KDO28871.1 - 0.0031 17.1 0.0 0.0068 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 KDO28871.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_23 PF13489.6 KDO28871.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO28871.1 - 0.03 15.0 0.0 0.068 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KDO28871.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KDO28871.1 - 0.082 12.3 0.0 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 Tellurite resistance protein TehB PrmA PF06325.13 KDO28871.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S5_C PF03719.15 KDO28872.1 - 1.3e-18 66.2 0.0 2.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KDO28872.1 - 4.3e-14 52.2 0.2 8.3e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Kinesin PF00225.23 KDO28873.1 - 2.3e-97 325.9 0.8 4e-97 325.1 0.8 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO28873.1 - 1e-24 87.2 0.6 8.3e-24 84.2 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding RILP PF11461.8 KDO28873.1 - 0.042 14.1 1.0 0.16 12.2 1.0 2.0 1 0 0 1 1 1 0 Rab interacting lysosomal protein RED_N PF07808.13 KDO28874.1 - 1.1e-09 38.2 12.5 6.6e-06 25.9 0.0 4.0 3 2 1 4 4 4 3 RED-like protein N-terminal region FAD-SLDH PF12318.8 KDO28874.1 - 0.062 13.4 0.8 8.1 6.5 0.2 2.8 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Elicitin PF00964.17 KDO28875.1 - 2.1e-05 24.5 3.0 2.1e-05 24.5 3.0 3.9 3 1 0 3 3 3 1 Elicitin Elicitin PF00964.17 KDO28876.1 - 3.3 7.9 25.0 0.16 12.1 6.1 3.4 2 1 1 3 3 3 0 Elicitin BT1 PF03092.16 KDO28878.1 - 3.8e-11 41.9 1.6 3.8e-11 41.9 1.6 3.2 2 1 2 4 4 4 2 BT1 family PUCC PF03209.15 KDO28878.1 - 0.0011 18.1 5.0 0.014 14.4 0.4 2.8 2 0 0 2 2 2 2 PUCC protein E1-E2_ATPase PF00122.20 KDO28878.1 - 7.8 6.0 8.6 0.51 9.8 0.3 2.9 3 0 0 3 3 3 0 E1-E2 ATPase BT1 PF03092.16 KDO28879.1 - 3.7e-10 38.7 10.6 1.2e-09 37.0 3.2 3.0 2 1 0 2 2 2 2 BT1 family PUCC PF03209.15 KDO28879.1 - 7.9e-06 25.1 0.4 7.9e-06 25.1 0.4 2.2 3 0 0 3 3 3 1 PUCC protein BT1 PF03092.16 KDO28880.1 - 2.6e-12 45.8 13.8 3.4e-10 38.8 1.0 3.6 3 1 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO28880.1 - 0.003 16.6 9.6 0.01 14.9 0.3 2.9 3 0 0 3 3 3 2 PUCC protein Dicer_N PF17895.1 KDO28880.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain DUF2085 PF09858.9 KDO28880.1 - 1 9.9 8.7 1.8 9.1 1.9 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) BT1 PF03092.16 KDO28881.1 - 7.1e-10 37.7 8.0 6.6e-09 34.5 2.3 2.4 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 KDO28881.1 - 0.00024 20.2 2.2 0.00043 19.4 0.5 2.3 2 0 0 2 2 2 1 PUCC protein DUF1772 PF08592.11 KDO28881.1 - 4.2 7.7 8.3 11 6.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DUF2085 PF09858.9 KDO28881.1 - 6.2 7.4 12.3 2.2 8.8 2.7 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2085) ABC2_membrane PF01061.24 KDO28882.1 - 3.5e-65 219.4 66.0 3e-34 118.3 30.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO28882.1 - 1.5e-33 116.2 0.0 9.5e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO28882.1 - 8.1e-06 25.9 0.0 0.47 10.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO28882.1 - 1.2e-05 25.3 0.0 0.00047 20.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KDO28882.1 - 2.5e-05 23.9 0.6 0.18 11.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KDO28882.1 - 3.7e-05 23.4 1.1 0.0075 16.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO28882.1 - 0.00011 22.6 0.7 0.24 11.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KDO28882.1 - 0.00062 20.0 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KDO28882.1 - 0.00063 19.9 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KDO28882.1 - 0.001 18.2 45.0 0.036 13.2 17.5 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA PF00004.29 KDO28882.1 - 0.0022 18.4 0.9 0.22 11.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KDO28882.1 - 0.0027 17.7 0.1 0.89 9.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KDO28882.1 - 0.0048 16.6 1.0 2 8.1 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KDO28882.1 - 0.013 16.0 0.2 0.65 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KDO28882.1 - 0.017 14.5 0.1 16 4.8 0.0 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KDO28882.1 - 0.027 14.9 0.9 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO28882.1 - 0.027 15.0 0.2 8.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO28882.1 - 0.03 14.0 1.6 3.4 7.3 0.5 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KDO28882.1 - 0.037 13.4 0.1 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 KDO28882.1 - 0.045 14.1 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 KDO28882.1 - 0.063 12.6 3.2 10 5.3 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 KDO28882.1 - 0.073 13.4 1.1 0.92 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KDO28882.1 - 0.089 12.4 2.2 5.6 6.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO28882.1 - 0.12 12.2 2.5 5.7 6.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 KDO28882.1 - 0.14 11.6 1.1 6.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein MCM PF00493.23 KDO28882.1 - 0.15 11.2 0.2 0.88 8.6 0.1 2.2 2 0 0 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 KDO28882.1 - 0.31 10.9 2.2 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 NTPase BT1 PF03092.16 KDO28883.1 - 5.8e-11 41.3 14.4 1e-09 37.2 2.0 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO28883.1 - 0.0008 18.5 0.5 0.0008 18.5 0.5 2.5 2 0 0 2 2 2 1 PUCC protein E1-E2_ATPase PF00122.20 KDO28883.1 - 2.8 7.4 6.9 0.22 11.1 0.3 2.4 3 0 0 3 3 3 0 E1-E2 ATPase DHHC PF01529.20 KDO28884.1 - 1.4e-16 60.8 3.1 1.4e-16 60.8 3.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase BT1 PF03092.16 KDO28885.1 - 1e-20 73.5 14.6 3.3e-19 68.5 4.4 2.2 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 KDO28885.1 - 4.3e-09 35.9 1.9 4.3e-09 35.9 1.9 1.9 1 1 1 2 2 2 1 PUCC protein ADK PF00406.22 KDO28886.1 - 2.9e-32 111.9 0.0 4.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KDO28886.1 - 7e-20 71.8 0.0 1.9e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO28886.1 - 1.6e-08 35.2 0.0 4.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO28886.1 - 1.4e-07 31.8 0.0 5e-07 30.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KDO28886.1 - 0.00057 19.6 0.1 0.039 13.6 0.0 2.4 1 1 1 2 2 2 1 Thymidylate kinase Cytidylate_kin PF02224.18 KDO28886.1 - 0.00071 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 KDO28886.1 - 0.00075 19.9 0.1 0.0023 18.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KDO28886.1 - 0.00092 19.5 0.1 0.0032 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KDO28886.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KDO28886.1 - 0.015 15.8 0.0 0.045 14.3 0.0 2.0 1 1 0 1 1 1 0 ABC transporter SKI PF01202.22 KDO28886.1 - 0.018 15.2 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_22 PF13401.6 KDO28886.1 - 0.024 14.9 0.1 0.066 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KDO28886.1 - 0.031 14.1 0.2 0.066 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO28886.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 KDO28886.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KDO28886.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Methyltransf_25 PF13649.6 KDO28887.1 - 1.4e-18 67.4 0.0 3.5e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO28887.1 - 1e-15 57.8 0.0 1.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO28887.1 - 6.6e-15 55.5 0.0 1.5e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO28887.1 - 1.1e-13 51.8 0.0 1.8e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO28887.1 - 1.9e-13 50.6 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO28887.1 - 3.3e-10 39.8 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KDO28887.1 - 2.4e-05 23.8 0.0 4.6e-05 22.8 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KDO28887.1 - 2.6e-05 23.7 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KDO28887.1 - 0.00022 20.6 0.0 0.00029 20.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KDO28887.1 - 0.00086 19.1 0.0 0.0032 17.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF938) CheR PF01739.18 KDO28887.1 - 0.0012 18.4 0.0 0.018 14.5 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KDO28887.1 - 0.0015 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KDO28887.1 - 0.0065 16.5 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KDO28887.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 KDO28887.1 - 0.028 14.2 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase DASH_Dad2 PF08654.10 KDO28888.1 - 2.2e-06 28.0 0.1 2.6e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KDO28888.1 - 0.012 15.3 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 ARID PF01388.21 KDO28889.1 - 3.5e-09 37.2 0.0 7.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KDO28889.1 - 0.00089 18.6 0.0 0.69 9.2 0.0 2.4 2 0 0 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa Img2 PF05046.14 KDO28890.1 - 9.9e-18 64.2 0.0 1.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 KDO28890.1 - 0.15 12.6 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 DUF2070 PF09843.9 KDO28891.1 - 5.3 5.2 10.1 6.2 5.0 10.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2530 PF10745.9 KDO28891.1 - 8.4 6.7 13.6 13 6.1 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4381 PF14316.6 KDO28891.1 - 9.1 6.5 8.5 0.49 10.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DASH_Duo1 PF08651.10 KDO28892.1 - 0.00078 19.2 1.2 0.001 18.8 1.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 WXG100 PF06013.12 KDO28892.1 - 0.0039 17.4 0.9 0.0057 16.9 0.9 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Matrilin_ccoil PF10393.9 KDO28892.1 - 0.051 13.5 0.2 0.066 13.1 0.2 1.2 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HisG PF01634.18 KDO28893.1 - 1.4e-54 184.3 0.1 2e-54 183.9 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KDO28893.1 - 9.1e-26 89.8 0.0 1.7e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain DoxX PF07681.12 KDO28893.1 - 0.042 14.4 0.0 0.11 13.1 0.0 1.6 1 1 0 1 1 1 0 DoxX SBP_bac_3 PF00497.20 KDO28893.1 - 0.056 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF4527 PF15030.6 KDO28894.1 - 0.2 11.1 1.8 0.22 10.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) zf_C2H2_ZHX PF18387.1 KDO28895.1 - 1.2e-06 28.0 11.8 1.5 8.5 0.0 6.0 6 0 0 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KDO28895.1 - 2.5e-06 27.7 30.0 0.56 10.5 0.2 7.1 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KDO28895.1 - 1.2e-05 24.9 13.3 2.3 8.1 0.0 5.8 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KDO28895.1 - 0.00058 20.2 7.9 0.27 11.6 0.1 5.0 4 2 1 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KDO28895.1 - 0.003 18.3 33.8 1 10.4 0.1 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger CpXC PF14353.6 KDO28895.1 - 0.0039 17.2 7.0 0.46 10.5 0.0 3.8 3 1 1 4 4 4 1 CpXC protein zf-C2H2_9 PF16293.5 KDO28895.1 - 0.062 13.2 21.7 0.48 10.3 0.1 5.3 7 0 0 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KDO28895.1 - 0.065 13.7 30.8 0.91 10.1 2.0 7.5 8 1 0 8 8 7 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 KDO28895.1 - 0.15 12.4 4.0 0.75 10.1 0.1 3.0 2 2 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KDO28895.1 - 0.17 12.4 29.0 1.3 9.6 0.0 6.8 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-met PF12874.7 KDO28895.1 - 0.56 10.7 4.7 0.69 10.4 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Sina PF03145.16 KDO28895.1 - 0.95 9.4 17.4 0.042 13.8 2.2 4.2 5 1 0 5 5 5 0 Seven in absentia protein family zf-C2H2_aberr PF17017.5 KDO28895.1 - 1.4 9.0 5.9 9.9 6.3 0.3 3.5 2 2 2 4 4 3 0 Aberrant zinc-finger zf_UBZ PF18439.1 KDO28895.1 - 1.6 8.4 9.8 2.1 8.0 0.0 4.7 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DUF629 PF04780.12 KDO28895.1 - 2.9 6.3 4.3 37 2.7 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF629) zf-met2 PF12907.7 KDO28896.1 - 0.23 11.6 2.8 0.76 10.0 0.9 2.3 2 0 0 2 2 2 0 Zinc-binding CCDC85 PF10226.9 KDO28897.1 - 0.00096 18.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 CCDC85 family FAM176 PF14851.6 KDO28897.1 - 0.006 16.2 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 FAM176 family DivIC PF04977.15 KDO28897.1 - 0.0061 16.3 0.2 0.0061 16.3 0.2 2.4 2 1 0 2 2 2 1 Septum formation initiator DUF3382 PF11862.8 KDO28897.1 - 0.071 13.4 1.2 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) APG6_N PF17675.1 KDO28897.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMEM237 PF15383.6 KDO28897.1 - 0.15 11.1 0.2 0.78 8.8 0.0 2.0 1 1 1 2 2 2 0 Transmembrane protein 237 FliD_N PF02465.18 KDO28897.1 - 0.54 11.0 6.6 0.11 13.3 1.7 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4726 PF15855.5 KDO28897.1 - 1.1 9.5 7.8 0.078 13.2 0.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) Pkinase PF00069.25 KDO28898.1 - 2.1e-48 165.0 0.0 3.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28898.1 - 1.5e-20 73.6 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO28898.1 - 2.3e-06 27.1 0.0 4.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO28898.1 - 0.001 18.7 0.0 0.0027 17.3 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KDO28898.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 2.9 2 2 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO28898.1 - 0.0032 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain SHE3 PF17078.5 KDO28898.1 - 0.0041 16.9 0.1 0.0088 15.8 0.0 1.4 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 Myosin_tail_1 PF01576.19 KDO28898.1 - 0.074 10.8 0.2 0.11 10.3 0.2 1.1 1 0 0 1 1 1 0 Myosin tail Mod_r PF07200.13 KDO28898.1 - 0.11 12.5 0.5 0.19 11.8 0.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TolA_bind_tri PF16331.5 KDO28898.1 - 0.15 12.1 2.3 0.36 11.0 2.3 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation HrpB7 PF09486.10 KDO28898.1 - 0.18 12.2 10.1 0.041 14.3 6.6 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ZapB PF06005.12 KDO28898.1 - 1.6 9.2 3.7 1.1 9.8 1.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB EF-hand_1 PF00036.32 KDO28899.1 - 0.00011 21.5 3.0 0.00012 21.3 0.2 2.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KDO28899.1 - 0.00056 19.6 0.1 0.00056 19.6 0.1 2.2 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KDO28899.1 - 0.00067 20.1 1.1 0.00094 19.6 1.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO28899.1 - 0.013 15.0 0.4 0.062 12.8 0.0 2.4 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 KDO28899.1 - 0.086 12.7 0.2 0.086 12.7 0.2 2.0 3 0 0 3 3 3 0 EF-hand domain pair Melibiase_2 PF16499.5 KDO28899.1 - 0.11 11.7 0.9 3.7 6.6 0.2 2.0 1 1 1 2 2 2 0 Alpha galactosidase A Ran_BP1 PF00638.18 KDO28900.1 - 5.8e-07 29.8 0.0 9.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KDO28900.1 - 2e-05 25.1 8.0 2e-05 25.1 8.0 5.8 3 2 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) B9-C2 PF07162.11 KDO28901.1 - 1.2e-42 145.9 0.0 1.4e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein CTP_transf_like PF01467.26 KDO28902.1 - 3.2e-29 101.9 0.0 4.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 KDO28902.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5639) 6PGD PF00393.19 KDO28903.1 - 0.089 12.2 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain RNA_pol_Rpb6 PF01192.22 KDO28906.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pes-10 PF07149.11 KDO28906.1 - 7.7 5.5 11.6 12 4.8 11.6 1.5 1 1 0 1 1 1 0 Pes-10 EGF_2 PF07974.13 KDO28907.1 - 1.9e-17 63.3 54.3 1.9e-06 28.1 10.9 5.6 5 1 0 5 5 5 5 EGF-like domain EGF PF00008.27 KDO28907.1 - 0.0014 18.9 51.4 0.016 15.5 1.5 5.7 4 2 1 5 5 5 3 EGF-like domain Laminin_EGF PF00053.24 KDO28907.1 - 0.0028 17.8 21.6 0.012 15.8 5.7 4.9 3 2 1 4 4 4 3 Laminin EGF domain DUF3348 PF11828.8 KDO28908.1 - 0.018 14.7 0.5 0.018 14.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3348) MatE PF01554.18 KDO28909.1 - 4.2e-51 172.8 33.1 9e-27 93.7 9.8 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO28909.1 - 1.2 9.1 42.5 0.098 12.7 2.2 4.5 2 2 3 5 5 5 0 Polysaccharide biosynthesis C-terminal domain Ras PF00071.22 KDO28910.1 - 3.1e-58 195.9 0.1 3.6e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO28910.1 - 2.7e-36 124.4 0.1 6.2e-36 123.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO28910.1 - 3.2e-12 46.3 0.1 3.5e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KDO28910.1 - 4.1e-07 30.1 0.9 0.021 14.7 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 KDO28910.1 - 4.4e-06 26.2 0.0 5.4e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO28910.1 - 7.1e-05 22.9 0.0 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO28910.1 - 0.00011 21.8 0.1 0.00085 18.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO28910.1 - 0.0018 17.7 0.1 0.0037 16.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KDO28910.1 - 0.011 16.2 0.1 0.031 14.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KDO28910.1 - 0.02 14.6 0.0 0.44 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO28910.1 - 0.024 13.8 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KDO28910.1 - 0.027 14.7 0.1 0.34 11.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KDO28910.1 - 0.028 13.8 0.0 0.25 10.7 0.0 2.2 2 2 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KDO28910.1 - 0.028 14.4 0.0 0.21 11.6 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO28910.1 - 0.032 14.6 0.2 0.074 13.4 0.2 1.8 1 1 1 2 2 2 0 AAA ATPase domain AP_endonuc_2 PF01261.24 KDO28910.1 - 0.033 13.6 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel AAA_7 PF12775.7 KDO28910.1 - 0.037 13.5 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Lar_N PF09861.9 KDO28910.1 - 0.054 12.7 0.0 0.092 11.9 0.0 1.5 1 1 0 1 1 1 0 Lactate racemase N-terminal domain MCR_beta PF02241.18 KDO28910.1 - 0.089 12.4 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain G-alpha PF00503.20 KDO28910.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 KDO28910.1 - 0.095 13.1 0.1 6.2 7.3 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hpr_kinase_C PF07475.12 KDO28910.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 KDO28910.1 - 0.16 11.7 0.2 0.47 10.2 0.2 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain PPR PF01535.20 KDO28911.1 - 0.0013 18.9 0.1 16 6.0 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 KDO28911.1 - 0.061 13.5 0.0 7.3 6.9 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family ANAPC3 PF12895.7 KDO28911.1 - 0.069 13.4 0.3 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.7 KDO28912.1 - 1.9e-25 89.2 19.3 1.9e-06 28.4 0.2 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28912.1 - 3.7e-18 65.4 31.4 0.00082 19.6 0.1 10.7 2 1 9 11 11 11 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28912.1 - 1.8e-14 53.9 26.1 0.00065 20.2 0.1 8.4 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28912.1 - 9.4e-06 25.6 24.5 9.1 7.2 0.0 11.1 11 1 2 13 13 13 2 Ankyrin repeat DUF5049 PF16468.5 KDO28912.1 - 2.4e-05 24.2 0.4 8.8 6.3 0.0 5.7 4 1 3 7 7 7 1 Domain of unknown function (DUF5049) Peripla_BP_6 PF13458.6 KDO28912.1 - 0.068 12.8 1.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein Tom37 PF10568.9 KDO28912.1 - 0.12 12.7 0.0 5.9 7.2 0.1 2.7 3 0 0 3 3 3 0 Outer mitochondrial membrane transport complex protein Ank PF00023.30 KDO28912.1 - 0.12 12.9 23.4 6.2 7.4 1.3 7.9 6 4 1 7 7 7 0 Ankyrin repeat DUF1707 PF08044.11 KDO28912.1 - 0.17 12.0 4.0 1.7 8.8 0.2 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1707) Adeno_E3_CR2 PF02439.15 KDO28913.1 - 0.5 10.2 0.0 0.5 10.2 0.0 2.6 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 MARVEL PF01284.23 KDO28913.1 - 0.58 10.2 6.1 0.89 9.6 6.1 1.3 1 0 0 1 1 1 0 Membrane-associating domain Vma12 PF11712.8 KDO28914.1 - 0.056 13.5 3.7 3.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MARVEL PF01284.23 KDO28914.1 - 0.35 10.9 17.5 0.68 9.9 17.5 1.5 1 1 0 1 1 1 0 Membrane-associating domain Acetyltransf_1 PF00583.25 KDO28915.1 - 1e-11 45.1 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO28915.1 - 7.4e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO28915.1 - 1.4e-07 31.5 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO28915.1 - 6.6e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KDO28915.1 - 0.00082 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KDO28915.1 - 0.0064 16.6 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ferric_reduct PF01794.19 KDO28916.1 - 0.049 13.7 6.6 0.053 13.6 5.8 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component MARVEL PF01284.23 KDO28917.1 - 0.0003 20.8 12.2 0.00041 20.4 12.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4203 PF13886.6 KDO28917.1 - 0.01 15.5 11.3 0.014 15.1 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) ATP1G1_PLM_MAT8 PF02038.16 KDO28917.1 - 0.036 13.5 0.4 0.036 13.5 0.4 2.7 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family YlmH_RBD PF17774.1 KDO28917.1 - 0.082 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH DUF3367 PF11847.8 KDO28917.1 - 0.18 9.7 4.6 0.23 9.3 4.6 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase MARVEL PF01284.23 KDO28918.1 - 0.0079 16.2 8.7 0.044 13.8 2.5 2.1 1 1 1 2 2 2 2 Membrane-associating domain DUF1218 PF06749.12 KDO28918.1 - 0.093 13.3 10.0 0.18 12.4 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) CnrY PF17524.2 KDO28918.1 - 0.16 12.2 4.3 0.093 13.0 1.5 2.1 1 1 0 2 2 2 0 Anti-sigma factor CnrY TrmO PF01980.16 KDO28919.1 - 1.2e-40 138.4 0.0 2.5e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 KDO28919.1 - 0.0026 17.8 0.1 0.0058 16.7 0.1 1.6 1 0 0 1 1 1 1 TrmO C-terminal domain COX16 PF14138.6 KDO28919.1 - 0.0049 17.3 0.3 0.02 15.4 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 DUF1192 PF06698.11 KDO28919.1 - 0.05 13.7 1.3 0.11 12.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ETF_alpha PF00766.19 KDO28920.1 - 5e-37 125.8 0.6 5e-37 125.8 0.6 2.3 2 1 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 KDO28920.1 - 1.5e-35 122.8 11.9 2.2e-35 122.2 11.9 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Herpes_capsid PF06112.11 KDO28920.1 - 1.1 9.3 12.4 5.8 7.0 1.1 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Ank_4 PF13637.6 KDO28921.1 - 9.5e-16 58.0 8.0 0.00036 21.1 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28921.1 - 8.1e-14 52.0 7.4 5.6e-05 23.7 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28921.1 - 1.5e-10 41.1 12.3 0.021 15.1 0.1 6.5 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28921.1 - 2.7e-07 30.4 5.3 9.7 7.1 0.0 6.9 6 1 1 7 7 7 2 Ankyrin repeat Ank PF00023.30 KDO28921.1 - 0.014 15.9 8.4 67 4.2 1.0 6.1 2 2 2 4 4 4 0 Ankyrin repeat DUF3322 PF11795.8 KDO28921.1 - 0.018 15.1 1.1 4.1 7.4 0.0 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF2807 PF10988.8 KDO28922.1 - 0.014 15.2 20.9 0.087 12.6 6.6 3.3 2 1 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain SCP2 PF02036.17 KDO28922.1 - 0.088 13.3 0.1 5.5 7.6 0.0 3.0 3 0 0 3 3 3 0 SCP-2 sterol transfer family MHYT PF03707.16 KDO28922.1 - 7.3 6.8 13.9 5.5 7.2 0.6 4.1 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat BT1 PF03092.16 KDO28923.1 - 2.3e-15 55.8 3.4 2.3e-15 55.8 3.4 2.4 1 1 0 2 2 2 2 BT1 family Robl_LC7 PF03259.17 KDO28924.1 - 3.5e-25 87.6 0.0 4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KDO28924.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 OSK PF17182.4 KDO28924.1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 OSK domain Mon1 PF03164.14 KDO28924.1 - 0.041 13.0 0.0 0.045 12.8 0.0 1.0 1 0 0 1 1 1 0 Trafficking protein Mon1 TPR_12 PF13424.6 KDO28925.1 - 1.8e-30 105.0 13.3 7.9e-13 48.5 0.3 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO28925.1 - 9.2e-17 59.7 6.0 0.0015 18.5 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO28925.1 - 2.6e-15 55.7 3.5 2.2e-06 27.3 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO28925.1 - 9.5e-15 53.7 2.1 0.001 18.8 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO28925.1 - 7.5e-13 47.5 4.3 0.0069 16.3 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO28925.1 - 6e-09 36.4 3.0 0.073 13.7 0.4 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO28925.1 - 7.8e-09 35.6 6.4 3.1 8.8 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO28925.1 - 2e-08 34.6 3.5 0.0002 21.8 1.0 4.6 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO28925.1 - 1.3e-07 31.3 0.1 4.2e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 KDO28925.1 - 4.1e-07 29.7 14.8 0.063 13.5 0.2 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO28925.1 - 0.0002 21.5 0.3 0.097 13.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO28925.1 - 0.00045 20.4 1.4 0.11 12.8 0.5 3.9 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KDO28925.1 - 0.00059 20.3 7.4 0.52 11.1 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 KDO28925.1 - 0.0011 19.1 1.5 0.022 14.8 0.1 2.9 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 KDO28925.1 - 0.0042 16.7 6.0 1.2 8.8 0.1 4.4 5 0 0 5 5 5 2 TPR repeat TPR_4 PF07721.14 KDO28925.1 - 0.053 14.2 6.2 6.5 7.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Defensin_propep PF00879.18 KDO28925.1 - 0.71 10.2 3.0 0.47 10.8 0.2 2.1 2 0 0 2 2 2 0 Defensin propeptide DUF4404 PF14357.6 KDO28925.1 - 1.1 9.9 5.2 0.38 11.4 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Glyco_transf_8 PF01501.20 KDO28926.1 - 0.00024 20.7 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 YL1 PF05764.13 KDO28927.1 - 3.4e-27 96.1 17.3 4.1e-26 92.6 17.3 2.0 1 1 0 1 1 1 1 YL1 nuclear protein Antimicrobial11 PF08106.11 KDO28927.1 - 4.2 7.6 6.6 24 5.2 3.4 3.2 2 1 0 2 2 2 0 Formaecin family EF-hand_7 PF13499.6 KDO28928.1 - 3.3e-15 56.3 1.6 8.6e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO28928.1 - 5.1e-13 47.6 0.8 0.0022 17.4 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO28928.1 - 1.9e-11 43.0 3.0 0.022 14.6 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KDO28928.1 - 2.5e-09 36.9 0.8 6.9e-05 22.6 0.1 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KDO28928.1 - 0.00074 19.8 1.8 0.11 12.8 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KDO28928.1 - 0.0019 17.6 1.1 0.6 9.7 0.0 3.3 3 0 0 3 3 3 1 EF hand CholecysA-Rec_N PF09193.10 KDO28928.1 - 0.019 14.9 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal EF-hand_4 PF12763.7 KDO28928.1 - 0.026 14.5 1.8 0.15 12.0 0.2 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DPCD PF14913.6 KDO28929.1 - 1.4e-59 200.7 0.0 1.8e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family Mcl1_mid PF12341.8 KDO28929.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region DMRL_synthase PF00885.19 KDO28930.1 - 3.8e-56 188.8 0.1 5e-56 188.4 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RNA_GG_bind PF10258.9 KDO28931.1 - 2.7e-16 59.4 2.1 4.6e-16 58.6 2.1 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain Arf PF00025.21 KDO28932.1 - 9.8e-46 155.4 0.0 1.2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KDO28932.1 - 7.5e-11 41.8 0.0 4.2e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KDO28932.1 - 4.3e-10 39.9 0.0 6.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KDO28932.1 - 7.4e-10 38.6 0.0 9.7e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KDO28932.1 - 9.7e-10 38.2 0.0 1.2e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KDO28932.1 - 1.6e-07 31.1 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KDO28932.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KDO28932.1 - 0.0026 17.4 0.1 0.1 12.2 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KDO28932.1 - 0.061 12.9 0.0 0.071 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KDO28932.1 - 0.089 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 KDO28932.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cyt_c_ox_IV PF12270.8 KDO28933.1 - 5.5 7.1 7.4 1.3 9.2 1.7 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Orbi_VP7 PF00897.17 KDO28935.1 - 0.1 11.6 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 Phosphodiest PF01663.22 KDO28936.1 - 1.4e-13 51.2 0.6 2.1e-13 50.6 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KDO28936.1 - 5.4e-05 22.7 0.3 9.5e-05 21.9 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KDO28936.1 - 0.0018 17.7 0.1 0.0042 16.5 0.1 1.6 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KDO28936.1 - 0.2 11.8 0.4 12 6.0 0.0 2.2 2 0 0 2 2 2 0 PglZ domain CS PF04969.16 KDO28937.1 - 0.0023 18.9 0.0 0.0049 17.9 0.0 1.6 1 0 0 1 1 1 1 CS domain FAM176 PF14851.6 KDO28937.1 - 0.055 13.1 2.6 0.12 12.0 2.6 1.5 1 1 0 1 1 1 0 FAM176 family DUF3245 PF11595.8 KDO28937.1 - 0.061 13.8 6.5 0.096 13.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) OAD_gamma PF04277.13 KDO28937.1 - 0.15 12.6 0.4 0.31 11.6 0.4 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pox_Ag35 PF03286.14 KDO28937.1 - 0.17 11.6 5.7 0.25 11.1 5.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 KDO28937.1 - 3.3 7.6 6.4 5.2 7.0 6.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 KDO28937.1 - 4.2 7.8 7.1 9.9 6.6 7.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3464 PF11947.8 KDO28937.1 - 6.3 6.5 5.5 11 5.8 5.5 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Cyclin_N PF00134.23 KDO28938.1 - 1.8e-13 50.4 0.2 2.8e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BT1 PF03092.16 KDO28939.1 - 5.8e-11 41.3 12.1 1.7e-08 33.2 1.7 3.3 2 2 0 2 2 2 2 BT1 family NiFe_hyd_3_EhaA PF17367.2 KDO28939.1 - 0.36 11.0 3.9 0.62 10.2 1.3 2.9 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF2975 PF11188.8 KDO28939.1 - 5.1 7.0 9.8 3.5 7.5 0.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) ABC_transp_aux PF09822.9 KDO28940.1 - 1.8e-08 34.2 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KDO28940.1 - 4.3e-06 25.8 0.0 0.031 13.1 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF4159 PF13709.6 KDO28940.1 - 0.021 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) ThuA PF06283.11 KDO28940.1 - 0.025 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation DUF4350 PF14258.6 KDO28940.1 - 0.13 12.7 0.0 0.49 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Na_Pi_cotrans PF02690.15 KDO28941.1 - 1.2e-25 90.3 28.4 1.3e-16 61.0 3.5 2.9 2 1 1 3 3 3 2 Na+/Pi-cotransporter Apyrase PF06079.11 KDO28942.1 - 9.2e-104 346.8 0.0 1.2e-103 346.4 0.0 1.1 1 0 0 1 1 1 1 Apyrase Ldt_C PF17969.1 KDO28943.1 - 0.04 14.7 0.0 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain DUF3450 PF11932.8 KDO28943.1 - 0.25 10.6 1.4 0.36 10.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.15 KDO28943.1 - 0.66 10.1 6.5 1.3 9.2 6.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KDO28943.1 - 0.71 10.0 7.8 1.1 9.5 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Peptidase_C1 PF00112.23 KDO28945.1 - 1.1e-31 110.6 0.2 1.5e-31 110.2 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease DUF4229 PF14012.6 KDO28945.1 - 0.092 12.9 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Peptidase_C1 PF00112.23 KDO28946.1 - 4e-41 141.5 0.2 4.9e-41 141.2 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Terminase_5 PF06056.12 KDO28946.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Peptidase_C1 PF00112.23 KDO28947.1 - 4.3e-36 125.0 0.1 6.2e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease VbhA PF18495.1 KDO28947.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 Antitoxin VbhA DDE_Tnp_Tn3 PF01526.17 KDO28947.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Tn3 transposase DDE domain Peptidase_C1 PF00112.23 KDO28948.1 - 1.3e-35 123.4 0.2 1.7e-35 123.1 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 KDO28949.1 - 4e-33 115.4 0.1 5.1e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease VbhA PF18495.1 KDO28949.1 - 0.14 12.0 1.2 0.18 11.7 0.2 1.7 2 0 0 2 2 2 0 Antitoxin VbhA Cellulose_synt PF03552.14 KDO28950.1 - 2.1e-26 92.7 7.6 1.7e-17 63.3 1.4 3.2 2 1 1 3 3 3 2 Cellulose synthase Glyco_trans_2_3 PF13632.6 KDO28950.1 - 1.2e-13 51.5 4.7 1.2e-13 51.5 4.7 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KDO28950.1 - 7.4e-12 45.6 0.0 2.4e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KDO28950.1 - 1.7e-08 34.4 0.1 2.5e-06 27.4 0.1 3.1 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KDO28950.1 - 6.9e-06 25.7 0.0 0.00049 19.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 DZR PF12773.7 KDO28950.1 - 0.0037 17.3 0.8 0.0093 16.0 0.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KDO28950.1 - 0.04 14.7 0.1 0.097 13.4 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family Nudix_N_2 PF14803.6 KDO28950.1 - 0.046 13.6 0.8 8.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KDO28950.1 - 0.049 13.4 2.3 0.15 11.8 2.3 1.9 1 0 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KDO28950.1 - 0.15 12.3 0.3 0.32 11.2 0.3 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Cellulose_synt PF03552.14 KDO28951.1 - 6.2e-23 81.2 7.2 3.2e-10 39.2 0.0 4.2 2 1 2 4 4 4 4 Cellulose synthase Glyco_trans_2_3 PF13632.6 KDO28951.1 - 8.3e-14 52.0 0.8 8.3e-14 52.0 0.8 3.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KDO28951.1 - 4.9e-12 46.2 0.0 1e-10 41.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KDO28951.1 - 1e-08 35.2 0.1 2e-06 27.8 0.1 3.0 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KDO28951.1 - 6.9e-06 25.6 0.0 0.00063 19.3 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 DZR PF12773.7 KDO28951.1 - 0.0029 17.6 0.3 0.0087 16.1 0.3 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KDO28951.1 - 0.054 14.2 0.5 0.14 12.9 0.5 1.7 1 0 0 1 1 1 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KDO28951.1 - 0.055 13.2 2.1 0.16 11.8 2.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KDO28951.1 - 0.17 11.9 1.0 9.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 KDO28951.1 - 1.4 8.5 3.3 58 3.3 3.9 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding Ank_5 PF13857.6 KDO28953.1 - 1.8e-08 34.4 0.2 4.4e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28953.1 - 1.7e-07 31.6 0.2 1.8e-05 25.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO28953.1 - 1.4e-06 28.8 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO28953.1 - 0.0065 16.9 0.0 0.091 13.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat WW PF00397.26 KDO28953.1 - 0.013 15.6 0.5 0.034 14.3 0.5 1.8 1 0 0 1 1 1 0 WW domain Ank PF00023.30 KDO28953.1 - 0.057 13.9 0.0 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Gmx_para_CXXCG PF09535.10 KDO28953.1 - 0.095 12.0 0.2 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) CENP-F_leu_zip PF10473.9 KDO28953.1 - 0.13 12.3 7.3 0.45 10.5 7.3 1.9 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PP2C PF00481.21 KDO28954.1 - 2.8e-32 112.3 0.0 3.7e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO28954.1 - 1.2e-07 31.6 0.2 0.016 14.8 0.1 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KDO28954.1 - 2.4e-07 30.9 0.2 0.019 14.9 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Lipase_3 PF01764.25 KDO28956.1 - 1.4e-31 109.2 1.0 2.5e-31 108.5 0.2 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO28956.1 - 0.0007 20.3 4.1 0.014 16.0 0.2 2.7 2 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO28956.1 - 0.00079 18.8 1.8 0.0016 17.8 0.3 2.3 3 1 0 3 3 3 1 Serine aminopeptidase, S33 DUF4523 PF15023.6 KDO28956.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF2974 PF11187.8 KDO28956.1 - 0.21 11.1 0.3 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF1289 PF06945.13 KDO28957.1 - 0.044 13.6 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Tom5 PF10642.9 KDO28958.1 - 0.34 11.0 1.7 0.74 9.9 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Glyco_hydro81C PF17652.1 KDO28959.1 - 8.6e-73 245.6 2.4 1.3e-72 245.0 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KDO28959.1 - 7.3e-38 130.5 0.0 1.5e-37 129.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Pkinase_Tyr PF07714.17 KDO28960.1 - 1.5e-50 171.9 0.0 2e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO28960.1 - 3.9e-48 164.1 0.0 6.6e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KDO28960.1 - 7.7e-11 41.6 14.4 3.8e-06 26.6 5.8 3.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO28960.1 - 1.9e-10 40.8 14.2 0.0001 22.6 2.4 4.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO28960.1 - 5.1e-06 25.5 0.0 8.8e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 KDO28960.1 - 9.5e-05 22.2 4.4 19 5.6 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich repeat Kdo PF06293.14 KDO28960.1 - 0.0065 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_1 PF00560.33 KDO28960.1 - 0.01 16.3 7.6 4.2 8.3 0.2 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat CopD PF05425.13 KDO28960.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein D Pkinase PF00069.25 KDO28961.1 - 1.2e-67 228.0 0.0 1.7e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28961.1 - 2.3e-40 138.5 0.0 3.8e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO28961.1 - 1.3e-22 80.3 0.0 5.1e-14 52.7 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 KDO28961.1 - 6.6e-07 29.7 6.8 5.3e-05 23.6 1.8 3.8 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KDO28961.1 - 4.1e-06 27.0 7.3 0.00047 20.4 1.7 3.5 3 2 0 3 3 3 2 Pleckstrin homology domain Arb2 PF09757.9 KDO28961.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain DZR PF12773.7 KDO28961.1 - 0.04 13.9 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon Kinase-like PF14531.6 KDO28961.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KDO28961.1 - 0.13 11.5 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_9 PF15410.6 KDO28961.1 - 0.2 12.0 0.1 3.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain FAM176 PF14851.6 KDO28961.1 - 1.4 8.6 7.8 19 4.9 0.2 3.7 4 0 0 4 4 4 0 FAM176 family Pkinase PF00069.25 KDO28962.1 - 7.3e-65 219.0 0.0 1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28962.1 - 4.9e-40 137.4 0.0 8e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO28962.1 - 2e-29 102.2 3.4 1.8e-13 50.9 0.0 4.4 4 1 0 4 4 3 3 PH domain PH_11 PF15413.6 KDO28962.1 - 3e-15 56.5 4.0 1.2e-06 28.9 0.1 4.1 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KDO28962.1 - 3.4e-07 30.3 0.0 0.016 15.3 0.0 2.8 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 KDO28962.1 - 2.1e-06 27.9 2.5 0.0022 18.3 0.2 3.6 3 1 1 4 4 4 2 Pleckstrin homology domain Kdo PF06293.14 KDO28962.1 - 0.00071 19.0 0.6 0.0014 18.0 0.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO28962.1 - 0.034 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO28962.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DZR PF12773.7 KDO28962.1 - 0.082 12.9 2.6 0.2 11.7 2.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon RIO1 PF01163.22 KDO28962.1 - 0.12 12.0 0.5 0.25 10.9 0.3 1.6 1 1 0 1 1 1 0 RIO1 family PH_9 PF15410.6 KDO28962.1 - 2.4 8.5 4.1 32 4.9 0.0 3.6 2 1 1 3 3 3 0 Pleckstrin homology domain zinc_ribbon_2 PF13240.6 KDO28962.1 - 4.8 7.0 7.7 22 5.0 7.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain TRAM_LAG1_CLN8 PF03798.16 KDO28963.1 - 2e-33 115.8 14.8 2.9e-33 115.3 14.8 1.2 1 0 0 1 1 1 1 TLC domain DUF1201 PF06716.11 KDO28963.1 - 0.065 13.3 0.7 0.065 13.3 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Cnd1 PF12717.7 KDO28964.1 - 1e-49 168.7 0.2 1e-49 168.7 0.2 4.4 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KDO28964.1 - 8.9e-16 58.2 2.6 8.9e-16 58.2 2.6 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 KDO28964.1 - 8.4e-05 22.5 1.2 2.5 8.6 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.23 KDO28964.1 - 0.00096 19.1 1.2 1.3 9.2 0.1 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO28964.1 - 0.0068 16.8 5.8 0.2 12.1 0.0 5.1 5 1 0 5 5 5 1 HEAT repeats DUF3427 PF11907.8 KDO28964.1 - 0.61 9.3 6.9 0.073 12.3 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3427) ESCRT-II PF05871.12 KDO28965.1 - 1.6e-34 119.2 0.0 2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Tctex-1 PF03645.13 KDO28966.1 - 3.5e-26 91.4 1.8 4e-26 91.3 1.8 1.0 1 0 0 1 1 1 1 Tctex-1 family Paramecium_SA PF01508.16 KDO28966.1 - 0.093 13.2 2.2 0.15 12.5 2.2 1.3 1 0 0 1 1 1 0 Paramecium surface antigen domain PilN PF05137.13 KDO28966.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Fimbrial assembly protein (PilN) Glyco_hydro_18 PF00704.28 KDO28967.1 - 1.6e-15 57.7 0.2 1e-14 55.0 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 KASH_CCD PF14662.6 KDO28968.1 - 5.3e-05 23.1 25.9 0.0012 18.7 21.8 3.3 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KDO28968.1 - 0.0073 16.3 21.7 0.0082 16.2 11.3 2.4 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KDO28968.1 - 0.0092 15.7 28.5 1.5 8.4 0.0 3.1 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 KDO28968.1 - 0.011 14.5 7.9 0.015 14.0 7.9 1.3 1 0 0 1 1 1 0 AAA domain HALZ PF02183.18 KDO28968.1 - 0.028 14.6 0.4 0.028 14.6 0.4 4.7 3 1 0 4 4 4 0 Homeobox associated leucine zipper CALCOCO1 PF07888.11 KDO28968.1 - 0.032 13.1 23.2 0.05 12.5 23.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like JIP_LZII PF16471.5 KDO28968.1 - 0.036 14.3 2.5 0.036 14.3 2.5 4.3 2 1 4 6 6 5 0 JNK-interacting protein leucine zipper II FH2 PF02181.23 KDO28968.1 - 0.051 12.7 6.4 0.061 12.4 5.5 1.6 1 1 0 1 1 1 0 Formin Homology 2 Domain GAS PF13851.6 KDO28968.1 - 0.051 12.9 26.2 0.033 13.5 18.8 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 KDO28968.1 - 0.053 12.8 5.7 0.1 11.9 5.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 KDO28968.1 - 0.055 13.3 1.1 0.055 13.3 1.1 4.6 1 1 5 6 6 6 0 Septum formation initiator Spo7 PF03907.13 KDO28968.1 - 0.075 12.5 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Spo7-like protein ADIP PF11559.8 KDO28968.1 - 0.08 13.0 21.5 0.074 13.1 7.0 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Duo1 PF08651.10 KDO28968.1 - 0.1 12.4 4.9 1.9 8.3 1.0 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 DUF1515 PF07439.11 KDO28968.1 - 0.1 12.6 6.8 1.7 8.7 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) FlaC_arch PF05377.11 KDO28968.1 - 0.11 12.8 12.2 7.7 7.0 0.0 5.0 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Macoilin PF09726.9 KDO28968.1 - 0.25 9.8 22.3 0.13 10.8 12.7 2.1 1 1 1 2 2 2 0 Macoilin family CLZ PF16526.5 KDO28968.1 - 0.28 11.6 15.9 0.46 10.9 1.5 4.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 KDO28968.1 - 0.29 11.8 19.0 43 4.8 7.5 4.0 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 KDO28968.1 - 0.32 11.4 17.3 14 6.1 17.9 2.7 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 KDO28968.1 - 0.42 10.7 7.2 0.16 12.0 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KDO28968.1 - 0.53 10.5 34.1 0.65 10.2 20.8 3.0 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.6 KDO28968.1 - 0.64 9.5 13.1 1.1 8.8 13.1 1.4 1 0 0 1 1 1 0 TMCO5 family zf-C4H2 PF10146.9 KDO28968.1 - 0.89 9.8 11.4 1.9 8.8 11.4 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 KDO28968.1 - 1.1 9.8 26.3 0.52 10.8 16.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Pup PF05639.11 KDO28968.1 - 1.1 10.2 3.7 1.8 9.5 1.3 2.5 1 1 1 2 2 2 0 Pup-like protein Pex19 PF04614.12 KDO28968.1 - 1.2 8.9 8.1 1.7 8.3 8.1 1.3 1 0 0 1 1 1 0 Pex19 protein family Cnn_1N PF07989.11 KDO28968.1 - 1.2 9.3 18.5 0.55 10.4 4.9 3.8 1 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Ribosomal_60s PF00428.19 KDO28968.1 - 1.2 9.7 13.7 5.4 7.7 7.4 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein PMEI PF04043.15 KDO28968.1 - 1.3 9.4 9.2 3.6 7.9 7.8 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Atg14 PF10186.9 KDO28968.1 - 1.8 7.6 15.8 3 6.8 15.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RasGAP_C PF03836.15 KDO28968.1 - 2.4 8.3 11.4 1.6e+03 -0.8 11.4 3.5 1 1 0 1 1 1 0 RasGAP C-terminus Fib_alpha PF08702.10 KDO28968.1 - 2.6 8.2 9.1 2.4 8.4 2.7 3.2 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 KDO28968.1 - 2.9 7.1 10.8 0.22 10.8 2.8 2.3 1 1 1 2 2 2 0 FAM76 protein bZIP_1 PF00170.21 KDO28968.1 - 3.9 7.6 15.3 2.6 8.2 0.5 4.5 3 1 0 3 3 3 0 bZIP transcription factor Phage_GP20 PF06810.11 KDO28968.1 - 4 7.2 17.8 1.7 8.5 9.1 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 T3SSipB PF16535.5 KDO28968.1 - 4.6 7.7 21.1 14 6.1 1.0 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB Spc24 PF08286.11 KDO28968.1 - 5 7.4 16.4 35 4.7 4.5 3.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 KDO28968.1 - 5.6 6.1 6.3 7.6 5.7 4.6 1.9 1 1 1 2 2 2 0 TMPIT-like protein ZapB PF06005.12 KDO28968.1 - 6.4 7.3 28.6 12 6.4 4.8 4.5 2 1 2 4 4 4 0 Cell division protein ZapB DUF4200 PF13863.6 KDO28968.1 - 7.6 7.0 18.0 0.22 11.9 10.2 2.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 KDO28968.1 - 8.2 6.2 13.5 0.78 9.5 7.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 KDO28968.1 - 8.9 6.9 14.9 1.8 9.2 7.6 3.3 2 1 2 4 4 4 0 Syntaxin 6, N-terminal RINT1_TIP1 PF04437.13 KDO28969.1 - 1.3e-68 232.2 0.0 2.2e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF2451 PF10474.9 KDO28969.1 - 0.0011 18.8 0.0 0.0043 16.9 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Abhydrolase_1 PF00561.20 KDO28970.1 - 5.8e-14 52.4 0.2 3.9e-06 26.7 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO28970.1 - 1.5e-09 38.8 1.3 2.2e-09 38.3 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO28970.1 - 8e-05 22.0 0.0 0.12 11.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KDO28970.1 - 0.0022 17.7 0.0 0.0063 16.2 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KDO28970.1 - 0.012 15.8 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein zf-MYND PF01753.18 KDO28971.1 - 0.00092 19.3 13.4 0.00092 19.3 13.4 2.5 2 0 0 2 2 2 1 MYND finger PhetRS_B1 PF18262.1 KDO28971.1 - 0.033 14.4 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Mannosyl_trans3 PF11051.8 KDO28972.1 - 8.8e-35 120.4 0.0 1.2e-33 116.6 0.0 2.3 2 1 0 2 2 2 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 KDO28973.1 - 2.5e-32 112.3 0.0 7.3e-31 107.5 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative UCH PF00443.29 KDO28974.1 - 2.5e-72 243.5 0.0 3.3e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO28974.1 - 3.2e-11 43.4 0.0 0.0001 22.0 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 KDO28974.1 - 0.028 14.3 5.1 0.44 10.5 0.1 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Pkinase PF00069.25 KDO28975.1 - 3.2e-61 207.0 0.0 5.9e-59 199.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO28975.1 - 5.9e-27 94.6 0.0 2.6e-24 85.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO28975.1 - 6.9e-07 29.7 0.0 1.6e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 KDO28975.1 - 0.00059 19.3 0.2 0.0013 18.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_6 PF15406.6 KDO28975.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Haspin_kinase PF12330.8 KDO28975.1 - 0.0099 14.9 0.1 0.037 13.0 0.0 1.8 1 1 1 2 2 2 1 Haspin like kinase domain PH_11 PF15413.6 KDO28975.1 - 0.031 14.7 0.1 0.19 12.1 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 KDO28975.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO28975.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-C2H2 PF00096.26 KDO28976.1 - 7e-10 38.8 9.9 0.00015 22.0 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO28976.1 - 7.5e-07 29.3 15.1 1.5e-05 25.2 2.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO28976.1 - 0.0015 19.2 15.1 0.0068 17.2 2.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KDO28976.1 - 0.0089 15.8 2.9 0.056 13.2 0.2 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type Chorismate_bind PF00425.18 KDO28977.1 - 1.2e-96 323.2 0.0 4.5e-96 321.4 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KDO28977.1 - 7e-24 84.7 0.0 2.3e-22 79.7 0.0 2.5 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region DUF908 PF06012.12 KDO28978.1 - 0.016 14.6 0.4 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Ank_2 PF12796.7 KDO28979.1 - 1.8e-19 70.1 3.6 5.8e-05 23.6 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO28979.1 - 4.9e-16 58.6 13.0 0.23 11.8 0.0 9.7 4 2 7 11 11 11 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO28979.1 - 1.6e-10 41.3 6.2 0.057 14.0 0.0 6.7 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO28979.1 - 5.8e-09 35.5 9.9 0.97 10.2 0.0 9.4 9 1 1 10 10 10 2 Ankyrin repeat Ank PF00023.30 KDO28979.1 - 0.00024 21.4 3.5 11 6.7 0.0 6.3 5 1 1 6 6 6 1 Ankyrin repeat Anoctamin PF04547.12 KDO28981.1 - 1.7e-94 317.2 3.1 6.6e-52 176.8 1.8 2.0 1 1 1 2 2 2 2 Calcium-activated chloride channel HTH_57 PF18679.1 KDO28981.1 - 0.0051 17.1 0.0 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 ThcOx helix turn helix domain F_actin_cap_B PF01115.17 KDO28983.1 - 5.3e-48 163.7 0.0 7.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Peptidase_C1 PF00112.23 KDO28983.1 - 5.3e-36 124.8 1.1 7.9e-36 124.2 1.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Cu2_monoox_C PF03712.15 KDO28984.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Catalase PF00199.19 KDO28985.1 - 1.1e-187 623.9 0.0 1.3e-187 623.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KDO28985.1 - 6.8e-21 74.2 0.2 2.4e-20 72.5 0.1 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF3638 PF12340.8 KDO28986.1 - 6e-30 104.3 0.7 1.8e-29 102.7 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KDO28986.1 - 2e-15 55.8 0.1 6e-15 54.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Thioredoxin_8 PF13905.6 KDO28986.1 - 2.2e-14 53.5 0.0 7.5e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like UBA PF00627.31 KDO28986.1 - 0.0012 18.6 0.0 0.0039 17.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-RanBP PF00641.18 KDO28986.1 - 0.0013 18.0 1.5 0.0013 18.0 1.5 4.8 4 0 0 4 4 4 2 Zn-finger in Ran binding protein and others EF-hand_1 PF00036.32 KDO28986.1 - 0.0055 16.2 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 EF hand DUF778 PF05608.12 KDO28986.1 - 0.04 14.3 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Thioredoxin_4 PF13462.6 KDO28986.1 - 0.046 13.9 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin EF-hand_6 PF13405.6 KDO28986.1 - 0.072 13.1 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KDO28986.1 - 0.082 13.4 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Thioredoxin_2 PF13098.6 KDO28986.1 - 0.1 13.1 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain EF-hand_5 PF13202.6 KDO28986.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 EF hand Tcp11 PF05794.13 KDO28987.1 - 1.3e-47 163.0 4.6 1.3e-47 163.0 4.6 2.3 2 1 0 2 2 2 1 T-complex protein 11 BTRD1 PF17660.1 KDO28987.1 - 1 9.2 3.7 55 3.7 0.6 3.6 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 LCD1 PF09798.9 KDO28987.1 - 1 7.8 6.3 1.6 7.2 6.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Sensor PF13796.6 KDO28987.1 - 6.3 6.8 11.4 0.8 9.7 2.9 3.4 3 2 0 3 3 3 0 Putative sensor IBR PF01485.21 KDO28988.1 - 4e-20 71.8 27.3 8.6e-12 45.1 5.4 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-dskA_traR PF01258.17 KDO28988.1 - 4.4 7.3 13.1 0.64 10.0 2.7 3.0 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Tudor-knot PF11717.8 KDO28989.1 - 0.0014 18.5 1.8 0.0019 18.0 0.2 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Got1 PF04178.12 KDO28990.1 - 6.1e-30 104.0 11.5 8.7e-30 103.4 11.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_C50 PF03568.17 KDO28991.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C50 MatE PF01554.18 KDO28992.1 - 2.9e-45 153.8 26.5 5.1e-26 91.2 7.4 2.2 2 0 0 2 2 2 2 MatE Adeno_E3_CR2 PF02439.15 KDO28992.1 - 0.054 13.3 2.1 0.086 12.6 0.1 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SKN1 PF03935.15 KDO28993.1 - 5.1e-63 213.2 19.8 8.6e-41 139.9 12.1 4.3 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2431 PF10354.9 KDO28995.1 - 2.7e-28 99.3 0.0 4.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_4 PF13894.6 KDO28995.1 - 1.5e-12 47.2 13.4 0.037 14.9 1.2 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KDO28995.1 - 3.2e-11 43.2 2.2 0.0068 16.7 0.6 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KDO28995.1 - 1.5e-08 34.6 10.0 0.26 11.8 0.3 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KDO28995.1 - 2.1e-05 24.8 10.1 0.29 11.5 2.8 4.3 2 2 1 3 3 3 2 C2H2 type zinc-finger (2 copies) MTS PF05175.14 KDO28995.1 - 7.5e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2_6 PF13912.6 KDO28995.1 - 0.00028 20.8 13.5 0.2 11.7 0.0 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KDO28995.1 - 0.0018 18.6 7.1 10 6.7 0.5 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KDO28995.1 - 0.0054 17.1 2.0 9.5 6.8 0.0 4.4 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KDO28995.1 - 0.013 15.8 0.1 0.06 13.7 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KDO28995.1 - 0.013 15.2 5.2 3.1 7.7 0.0 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type Methyltransf_25 PF13649.6 KDO28995.1 - 0.082 13.6 0.3 0.29 11.9 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO28995.1 - 0.12 13.0 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KDO28995.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase zf-C2H2_9 PF16293.5 KDO28995.1 - 0.36 10.7 5.6 0.92 9.4 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF629 PF04780.12 KDO28995.1 - 0.59 8.6 3.8 7 5.0 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zinc_ribbon_9 PF14369.6 KDO28995.1 - 1.8 8.9 7.3 5.2 7.4 1.1 3.6 3 0 0 3 3 3 0 zinc-ribbon Rhomboid PF01694.22 KDO28996.1 - 6e-21 75.0 14.2 1.6e-14 54.1 3.4 2.7 3 0 0 3 3 3 2 Rhomboid family DAP3 PF10236.9 KDO28997.1 - 3.4e-18 65.9 0.0 6.2e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 CotH PF08757.11 KDO28999.1 - 0.0006 19.4 1.3 0.24 10.9 0.0 2.2 1 1 1 2 2 2 2 CotH kinase protein DUF445 PF04286.12 KDO28999.1 - 0.00099 19.0 4.5 0.21 11.4 5.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF445) DnaI_N PF07319.11 KDO28999.1 - 0.0024 18.5 6.2 5.7 7.7 1.3 4.0 2 1 3 5 5 5 1 Primosomal protein DnaI N-terminus RTTN_N PF14726.6 KDO28999.1 - 0.0097 16.7 4.0 0.035 14.9 0.7 2.5 1 1 1 2 2 2 1 Rotatin, an armadillo repeat protein, centriole functioning RdRP PF05183.12 KDO28999.1 - 0.03 13.0 2.3 0.038 12.6 2.3 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase SapB_1 PF05184.15 KDO28999.1 - 0.04 13.9 1.4 0.19 11.8 0.1 2.8 2 1 0 2 2 2 0 Saposin-like type B, region 1 Coatomer_E PF04733.14 KDO28999.1 - 0.054 12.9 2.7 4.8 6.5 0.8 2.2 2 0 0 2 2 2 0 Coatomer epsilon subunit DOT1 PF08123.13 KDO28999.1 - 0.06 12.9 0.3 0.12 11.9 0.3 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF3333 PF11812.8 KDO28999.1 - 0.087 13.0 1.4 0.24 11.6 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3333) T6PP_N PF18572.1 KDO28999.1 - 0.18 11.7 2.6 0.68 9.8 0.5 2.5 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF3819 PF12842.7 KDO28999.1 - 0.39 10.7 6.7 6.8 6.6 3.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3819) SIL1 PF16782.5 KDO28999.1 - 0.81 8.8 8.9 0.62 9.2 6.7 2.0 2 1 0 2 2 2 0 Nucleotide exchange factor SIL1 IZUMO PF15005.6 KDO28999.1 - 4.2 7.9 8.3 10 6.6 1.6 2.5 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated ATP-synt_G PF04718.15 KDO28999.1 - 9.9 7.1 7.4 17 6.3 1.7 2.9 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit Sugar_tr PF00083.24 KDO29000.1 - 7e-79 265.8 26.6 8.8e-79 265.5 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29000.1 - 1.1e-23 83.8 41.7 3.7e-19 68.9 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5310 PF17237.2 KDO29000.1 - 0.028 14.3 0.7 0.13 12.2 0.7 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5310) DUF2615 PF11027.8 KDO29000.1 - 0.15 12.2 0.0 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Skp1 PF01466.19 KDO29000.1 - 0.18 12.0 1.3 0.43 10.7 0.6 2.0 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Sugar_tr PF00083.24 KDO29001.1 - 4.5e-17 62.1 17.5 9.2e-12 44.6 6.5 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO29001.1 - 2.3e-08 33.4 8.8 1.7e-06 27.2 7.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KDO29001.1 - 0.0055 15.3 1.3 0.0055 15.3 1.3 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein YqhR PF11085.8 KDO29001.1 - 0.052 13.5 1.4 0.097 12.6 1.4 1.4 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF2615 PF11027.8 KDO29001.1 - 0.062 13.4 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Skp1 PF01466.19 KDO29001.1 - 0.11 12.7 0.5 0.19 11.9 0.5 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DUF5310 PF17237.2 KDO29001.1 - 0.2 11.6 2.4 0.55 10.1 2.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5310) DUF1712 PF08217.11 KDO29002.1 - 2.1e-09 36.4 0.0 5.1e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) MBDa PF16564.5 KDO29002.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Sugar_tr PF00083.24 KDO29003.1 - 9.3e-81 272.0 26.9 1.2e-80 271.6 26.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29003.1 - 4.2e-21 75.3 53.0 1.5e-19 70.2 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO29004.1 - 6.3e-75 252.7 23.5 5e-58 197.0 8.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO29004.1 - 6.1e-18 64.9 34.2 4.2e-17 62.1 28.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO29005.1 - 1.6e-22 80.0 6.5 1.8e-22 79.9 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29005.1 - 2.6e-05 23.3 7.6 3.4e-05 22.9 7.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TAT_signal PF10518.9 KDO29005.1 - 0.1 12.5 0.4 0.23 11.4 0.4 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Sugar_tr PF00083.24 KDO29006.1 - 2.2e-41 142.2 9.8 4.4e-41 141.2 9.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29006.1 - 8.2e-17 61.2 9.5 2.2e-16 59.7 9.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KDO29006.1 - 0.00047 18.7 0.9 0.00063 18.3 0.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KDO29006.1 - 0.00057 18.6 7.4 0.00085 18.0 1.0 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein LpxK PF02606.14 KDO29007.1 - 2.3e-57 194.6 0.6 1.7e-55 188.4 0.6 2.0 1 1 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Sugar_tr PF00083.24 KDO29008.1 - 5.3e-18 65.1 7.5 6.7e-18 64.8 7.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KDO29009.1 - 8.1e-80 268.9 22.9 1e-79 268.6 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29009.1 - 3.5e-23 82.1 33.7 3.8e-22 78.7 29.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO29010.1 - 8.2e-85 285.3 18.7 1.1e-84 284.9 18.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29010.1 - 3.9e-25 88.5 26.9 6.2e-25 87.9 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KDO29010.1 - 0.49 8.7 11.5 0.07 11.5 3.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector SfsA PF03749.13 KDO29011.1 - 5.9e-34 116.9 0.0 9e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 KDO29011.1 - 1e-18 67.2 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 SfsA N-terminal OB domain DUF4143 PF13635.6 KDO29011.1 - 0.032 14.4 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4143) NDK PF00334.19 KDO29012.1 - 5.1e-51 172.2 0.0 6.7e-51 171.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HOOK PF05622.12 KDO29013.1 - 1.2e-57 195.6 45.2 3.2e-57 194.2 45.2 1.6 1 1 0 1 1 1 1 HOOK protein CH PF00307.31 KDO29013.1 - 0.0011 19.1 0.0 0.0037 17.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KDO29013.1 - 0.0028 17.8 0.6 0.021 14.9 0.0 2.8 2 1 0 2 2 2 1 CH-like domain in sperm protein CENP-F_leu_zip PF10473.9 KDO29013.1 - 0.0031 17.5 17.3 0.0031 17.5 17.3 6.8 2 2 3 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CAMSAP_CH PF11971.8 KDO29013.1 - 0.012 15.5 0.1 0.079 12.8 0.0 2.3 2 0 0 2 2 2 0 CAMSAP CH domain PLAC9 PF15205.6 KDO29013.1 - 1.3 9.4 3.7 7.3 7.1 0.1 3.4 4 0 0 4 4 4 0 Placenta-specific protein 9 Arm PF00514.23 KDO29014.1 - 2.6e-17 62.2 2.2 1.6e-08 34.3 0.1 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO29014.1 - 9e-13 48.4 7.3 2.2e-09 37.6 0.9 2.3 1 1 1 2 2 2 2 HEAT repeats Arm_2 PF04826.13 KDO29014.1 - 1.4e-06 28.0 3.5 0.0027 17.2 0.5 2.0 1 1 1 2 2 2 2 Armadillo-like HEAT_EZ PF13513.6 KDO29014.1 - 0.00014 22.2 2.9 0.21 12.1 0.5 2.4 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.22 KDO29014.1 - 0.00072 19.6 2.5 0.97 9.9 0.1 3.0 3 0 0 3 3 3 2 HEAT repeat KAP PF05804.12 KDO29014.1 - 0.0021 16.3 0.3 0.0027 16.0 0.3 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.8 KDO29014.1 - 0.014 15.5 1.0 0.028 14.5 0.5 1.6 1 1 1 2 2 2 0 V-ATPase subunit H Adaptin_N PF01602.20 KDO29014.1 - 0.027 13.0 0.1 0.054 12.0 0.1 1.4 1 1 1 2 2 2 0 Adaptin N terminal region Aconitase_B_N PF11791.8 KDO29014.1 - 0.056 13.5 5.4 0.28 11.2 0.3 2.7 1 1 2 3 3 3 0 Aconitate B N-terminal domain UNC45-central PF11701.8 KDO29014.1 - 0.077 13.0 0.4 0.21 11.6 0.4 1.8 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Lipl32 PF12103.8 KDO29014.1 - 0.16 11.6 0.2 0.35 10.5 0.1 1.4 1 1 0 1 1 1 0 Surface lipoprotein of Spirochaetales order DUF3361 PF11841.8 KDO29014.1 - 0.41 10.6 2.2 0.38 10.7 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Myb_DNA-binding PF00249.31 KDO29015.1 - 3.9e-39 132.6 6.5 5.8e-14 52.0 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO29015.1 - 1.3e-36 124.7 1.0 7.5e-15 54.9 0.1 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO29015.1 - 0.00029 20.7 0.0 0.65 9.9 0.0 2.9 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KDO29015.1 - 0.0052 16.8 0.1 12 6.0 0.0 3.4 1 1 1 3 3 3 2 SLIDE MADF_DNA_bdg PF10545.9 KDO29015.1 - 0.0057 16.9 3.3 5.9 7.3 0.1 3.6 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KDO29015.1 - 0.019 15.0 0.6 5.4 7.2 0.0 3.1 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KDO29015.1 - 0.078 13.4 8.5 3.7 8.0 0.9 4.5 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Ectoine_synth PF06339.12 KDO29016.1 - 4.3e-24 85.1 0.0 5.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 KDO29016.1 - 0.019 14.7 0.2 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 KDO29016.1 - 0.022 14.3 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Pirin_C_2 PF17954.1 KDO29016.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.7 1 1 1 2 2 2 0 Quercetinase C-terminal cupin domain ASH PF15780.5 KDO29017.1 - 2.5e-28 98.2 0.6 0.00038 20.6 0.0 8.4 8 0 0 8 8 8 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KDO29017.1 - 5.9e-13 48.8 2.3 0.0074 16.4 0.0 6.8 6 0 0 6 6 6 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KDO29017.1 - 1.9e-07 30.9 0.4 0.68 9.8 0.0 5.6 5 0 0 5 5 5 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 KDO29017.1 - 3.5e-07 30.2 0.0 6 7.0 0.0 7.2 8 0 0 8 8 8 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 KDO29017.1 - 6.6e-07 29.5 1.3 0.13 12.5 0.1 5.1 5 0 0 5 5 5 2 Transmembrane protein 131-like SRP54 PF00448.22 KDO29017.1 - 0.00081 19.1 1.2 0.0014 18.3 1.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Parvo_coat_N PF08398.10 KDO29017.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Myb_DNA-binding PF00249.31 KDO29019.1 - 3.3e-40 136.0 10.2 3.3e-15 56.0 0.6 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO29019.1 - 1.8e-32 111.4 3.9 1.4e-14 54.1 0.1 3.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO29019.1 - 0.00029 20.7 0.1 0.77 9.7 0.1 3.4 3 0 0 3 3 3 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 KDO29019.1 - 0.0021 18.4 5.5 1.1 9.6 0.1 3.7 4 0 0 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KDO29019.1 - 0.014 15.5 0.4 0.54 10.4 0.1 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 KDO29019.1 - 0.031 14.3 0.2 1.9 8.6 0.0 3.0 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_4 PF13837.6 KDO29019.1 - 0.048 14.1 6.8 8.2 6.9 0.1 4.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain CDC24 PF06395.11 KDO29019.1 - 0.14 12.4 0.2 0.76 10.1 0.0 2.0 2 0 0 2 2 2 0 CDC24 Calponin Myb_DNA-binding PF00249.31 KDO29020.1 - 2.8e-31 107.4 4.7 1.1e-16 60.8 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO29020.1 - 3.3e-22 78.5 1.0 3.6e-15 56.0 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Spore_III_AB PF09548.10 KDO29020.1 - 0.011 15.9 0.1 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 KDO29020.1 - 0.027 14.8 0.6 0.44 11.0 0.1 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SPRY PF00622.28 KDO29021.1 - 2e-09 37.6 0.0 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 2 SPRY domain Neuralized PF07177.12 KDO29021.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Neuralized His_Phos_2 PF00328.22 KDO29022.1 - 5.5e-74 249.8 0.0 9.5e-72 242.4 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KDO29022.1 - 1e-37 128.2 0.1 2.4e-37 127.0 0.1 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KDO29022.1 - 8.4e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.22 KDO29022.1 - 0.26 11.0 1.2 1.6 8.4 0.1 2.7 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) YppF PF14178.6 KDO29023.1 - 0.047 13.6 0.3 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 YppF-like protein Trypsin_2 PF13365.6 KDO29024.1 - 1.6e-14 55.0 0.5 4.7e-14 53.5 0.5 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO29024.1 - 0.00067 19.5 0.1 0.00067 19.5 0.1 2.0 2 0 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 KDO29024.1 - 0.002 16.9 0.8 0.0031 16.2 0.8 1.1 1 0 0 1 1 1 1 Peptidase S46 Lactamase_B PF00753.27 KDO29025.1 - 8e-11 42.3 0.1 1.3e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily cNMP_binding PF00027.29 KDO29025.1 - 1.3e-08 34.8 0.0 0.0016 18.5 0.0 3.1 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 KDO29025.1 - 2.6e-07 30.4 0.0 6.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_8 PF13833.6 KDO29026.1 - 4.2e-08 32.9 0.1 1.9e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO29026.1 - 1.4e-05 24.6 0.3 4e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KDO29026.1 - 3.3e-05 23.1 0.2 8e-05 21.9 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO29026.1 - 0.00012 22.4 0.1 0.00023 21.5 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO29026.1 - 0.0071 15.8 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 EF hand DUF4455 PF14643.6 KDO29026.1 - 0.088 11.4 0.1 0.22 10.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4455) Ank_2 PF12796.7 KDO29028.1 - 4.7e-16 59.2 5.8 4.1e-05 24.1 0.5 5.9 4 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29028.1 - 4.9e-09 36.6 15.6 0.069 13.7 0.1 7.7 6 3 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29028.1 - 0.0025 18.1 10.7 38 4.8 0.1 7.6 5 2 3 8 8 8 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29028.1 - 0.0036 17.7 7.3 99 4.0 0.0 7.8 9 0 0 9 9 9 0 Ankyrin repeat DUF249 PF03158.13 KDO29028.1 - 0.077 12.7 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Multigene family 530 protein Ank PF00023.30 KDO29028.1 - 1.1 9.8 13.0 15 6.2 1.2 6.3 4 3 0 4 4 4 0 Ankyrin repeat cNMP_binding PF00027.29 KDO29029.1 - 1.8e-30 104.8 0.1 1.1e-16 60.7 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Thaumatin PF00314.17 KDO29030.1 - 0.0069 16.0 0.3 0.021 14.5 0.2 1.9 1 1 0 1 1 1 1 Thaumatin family tRNA_bind PF01588.20 KDO29031.1 - 2.6e-23 81.9 0.7 4.4e-23 81.2 0.7 1.4 1 1 0 1 1 1 1 Putative tRNA binding domain P34-Arc PF04045.14 KDO29032.1 - 4.1e-77 259.1 0.0 5e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Pkinase_Tyr PF07714.17 KDO29033.1 - 1.1e-48 165.7 0.0 1.7e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO29033.1 - 4.8e-48 163.8 0.0 7.9e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO29033.1 - 0.034 12.9 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DNA_pol_A_exo1 PF01612.20 KDO29034.1 - 7.4e-22 77.9 0.0 1.6e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease NTP_transf_2 PF01909.23 KDO29034.1 - 2.4e-10 40.6 0.0 7e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KDO29034.1 - 0.00014 22.0 0.0 0.00061 20.0 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KDO29034.1 - 0.00059 19.9 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Prion_bPrPp PF11587.8 KDO29036.1 - 0.002 17.9 0.7 0.002 17.9 0.7 2.4 2 0 0 2 2 2 1 Major prion protein bPrPp - N terminal COPIIcoated_ERV PF07970.12 KDO29037.1 - 3.8e-67 226.4 0.0 4.9e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KDO29037.1 - 5.8e-25 87.5 0.4 1.1e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) eIF2_C PF09173.11 KDO29038.1 - 9.1e-37 125.2 0.7 2.4e-36 123.8 0.7 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KDO29038.1 - 1.4e-23 83.5 0.5 1.1e-22 80.5 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KDO29038.1 - 1.3e-12 47.9 0.6 3.3e-12 46.6 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KDO29038.1 - 0.003 17.5 0.4 0.097 12.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KDO29038.1 - 0.0031 17.6 0.1 0.0098 16.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KDO29038.1 - 0.1 12.6 0.1 0.48 10.5 0.0 2.1 3 0 0 3 3 3 0 Dynamin family Glyco_transf_52 PF07922.11 KDO29038.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 MMR_HSR1_Xtn PF16897.5 KDO29038.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF1098 PF06497.11 KDO29038.1 - 0.18 12.3 0.9 0.41 11.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Snf7 PF03357.21 KDO29039.1 - 1.1e-10 41.4 0.2 1.5e-10 41.0 0.2 1.1 1 0 0 1 1 1 1 Snf7 Tropomyosin_1 PF12718.7 KDO29039.1 - 0.085 13.0 0.5 0.13 12.4 0.5 1.3 1 0 0 1 1 1 0 Tropomyosin like Mito_fiss_reg PF05308.11 KDO29040.1 - 0.0068 16.5 10.4 0.0068 16.5 10.4 2.8 1 1 0 2 2 2 1 Mitochondrial fission regulator DUF1796 PF08795.10 KDO29040.1 - 0.022 14.7 13.0 0.39 10.6 2.1 3.3 2 1 1 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) Trimer_CC PF08954.11 KDO29040.1 - 0.12 12.0 0.3 0.12 12.0 0.3 4.5 7 1 0 7 7 7 0 Trimerisation motif DUF1664 PF07889.12 KDO29040.1 - 0.81 9.7 33.2 1.3 9.0 4.5 5.4 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KDO29040.1 - 1.2 7.9 50.4 0.85 8.4 13.9 4.3 2 1 3 5 5 5 0 Spc7 kinetochore protein DivIC PF04977.15 KDO29040.1 - 1.3 8.9 46.3 0.053 13.3 1.7 7.2 5 2 2 8 8 8 0 Septum formation initiator Filament PF00038.21 KDO29040.1 - 2 7.9 48.9 0.16 11.5 4.9 4.6 2 1 3 5 5 5 0 Intermediate filament protein SlyX PF04102.12 KDO29040.1 - 5.1 7.8 42.4 1.8 9.3 2.8 7.1 5 1 2 7 7 7 0 SlyX FAD-SLDH PF12318.8 KDO29041.1 - 1.8 8.6 5.9 0.28 11.3 0.5 2.5 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PIG-S PF10510.9 KDO29041.1 - 8.2 5.1 9.4 0.79 8.5 4.4 1.8 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein RCC1 PF00415.18 KDO29042.1 - 2.3e-56 188.2 3.3 1.4e-13 51.3 0.0 6.7 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29042.1 - 3.5e-21 74.4 27.5 1.2e-07 31.4 3.5 6.9 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat CCT PF06203.14 KDO29043.1 - 1.2e-14 54.0 14.4 2.4e-14 53.1 14.4 1.5 1 0 0 1 1 1 1 CCT motif Ribosomal_L1 PF00687.21 KDO29044.1 - 3.2e-45 154.4 1.8 3.2e-45 154.4 1.8 2.4 3 1 0 3 3 3 1 Ribosomal protein L1p/L10e family Vps39_2 PF10367.9 KDO29045.1 - 1.5e-18 67.2 1.0 2.6e-18 66.5 0.2 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KDO29045.1 - 6.8e-16 58.5 0.2 5.9e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KDO29045.1 - 0.045 13.6 0.0 9.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Region in Clathrin and VPS RecA_dep_nuc PF16786.5 KDO29045.1 - 0.1 12.7 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Recombination enhancement, RecA-dependent nuclease TPR_7 PF13176.6 KDO29045.1 - 0.11 12.6 1.0 5.3 7.3 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat WH2 PF02205.20 KDO29046.1 - 1.1e-11 44.1 9.1 9.3e-09 34.8 1.1 3.2 3 0 0 3 3 3 2 WH2 motif WW PF00397.26 KDO29046.1 - 2.2e-11 43.6 4.1 4.2e-11 42.7 4.1 1.5 1 0 0 1 1 1 1 WW domain DnaJ PF00226.31 KDO29048.1 - 2.7e-24 85.1 7.3 6.7e-24 83.8 3.9 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KDO29048.1 - 1.8e-17 62.3 13.5 0.0024 17.6 0.2 9.3 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KDO29048.1 - 9.1e-17 60.5 0.2 0.15 11.7 0.0 8.4 7 2 2 9 9 8 4 TPR repeat TPR_2 PF07719.17 KDO29048.1 - 4.8e-16 57.5 20.3 0.013 15.6 0.0 9.5 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29048.1 - 3e-14 52.5 13.7 0.0069 17.1 0.1 7.3 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29048.1 - 2.7e-13 50.2 18.6 0.055 14.0 0.4 7.8 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29048.1 - 1.1e-10 40.8 7.9 0.2 11.8 0.0 6.2 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29048.1 - 1.4e-10 41.6 21.4 0.007 17.0 0.1 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29048.1 - 5.2e-10 38.7 11.5 0.47 10.8 0.0 8.3 6 2 2 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO29048.1 - 1e-07 32.0 16.7 0.0051 16.9 0.0 6.6 7 1 1 8 8 7 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 KDO29048.1 - 0.00018 20.9 1.1 0.27 10.7 0.0 4.5 5 0 0 5 5 5 1 SHNi-TPR TPR_17 PF13431.6 KDO29048.1 - 0.00057 20.1 4.7 3.8 8.1 0.0 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO29048.1 - 0.0009 19.7 7.9 3.9 8.3 0.0 6.9 6 1 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 KDO29048.1 - 0.0064 16.9 14.5 0.043 14.2 0.3 5.0 3 2 2 5 5 5 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 KDO29048.1 - 0.052 13.9 24.6 0.092 13.1 1.0 6.7 7 1 1 8 8 6 0 Tetratricopeptide repeat LAP2alpha PF11560.8 KDO29048.1 - 0.068 12.6 1.1 0.41 10.0 0.0 2.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 2 alpha Spectrin PF00435.21 KDO29048.1 - 0.12 12.8 3.2 4.7 7.7 0.2 3.5 2 1 1 3 3 3 0 Spectrin repeat ANAPC3 PF12895.7 KDO29048.1 - 0.39 11.0 19.8 0.053 13.7 2.0 5.1 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KDO29048.1 - 0.54 10.2 11.4 6.7 6.7 0.1 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 KDO29050.1 - 7.4e-18 64.4 2.2 1.5e-17 63.4 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 KDO29050.1 - 7.2e-09 35.1 20.0 0.027 14.3 0.3 6.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29050.1 - 1e-05 25.9 27.7 0.17 12.4 0.1 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO29050.1 - 5.9e-05 22.9 30.4 0.18 12.0 0.6 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29050.1 - 0.00041 20.9 3.1 0.00041 20.9 3.1 5.9 4 2 2 6 6 5 1 Tetratricopeptide repeat NARP1 PF12569.8 KDO29050.1 - 0.0058 15.6 7.1 0.0058 15.6 7.1 1.9 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 DUF5093 PF17011.5 KDO29050.1 - 0.053 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) TPR_11 PF13414.6 KDO29050.1 - 0.21 11.3 5.1 7.2 6.4 0.2 3.6 3 0 0 3 3 3 0 TPR repeat SHIPPO-rpt PF07004.12 KDO29050.1 - 0.56 11.2 4.2 11 7.1 0.2 3.5 3 0 0 3 3 2 0 Sperm-tail PG-rich repeat TPR_17 PF13431.6 KDO29050.1 - 0.57 10.7 8.8 2.3 8.8 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29050.1 - 0.8 10.1 8.4 46 4.6 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29050.1 - 3.7 7.8 8.4 9.6 6.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29050.1 - 3.8 8.6 37.8 1 10.4 0.2 7.9 6 2 2 8 8 7 0 Tetratricopeptide repeat DSPc PF00782.20 KDO29051.1 - 1.8e-17 63.4 0.0 2.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO29051.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KDO29051.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KDO29051.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate MerR-DNA-bind PF09278.11 KDO29052.1 - 0.0039 17.7 5.6 0.013 16.0 4.2 2.4 2 1 0 2 2 2 1 MerR, DNA binding CSRNP_N PF16019.5 KDO29052.1 - 0.027 14.4 7.0 0.16 11.8 7.0 2.0 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TALPID3 PF15324.6 KDO29052.1 - 0.85 7.2 9.1 1.3 6.6 9.1 1.2 1 0 0 1 1 1 0 Hedgehog signalling target WD40 PF00400.32 KDO29053.1 - 9e-38 127.6 25.2 6.9e-06 26.7 0.0 11.4 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29053.1 - 2.5e-18 66.1 3.3 3.7e-06 27.1 0.0 7.4 5 1 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KDO29053.1 - 8e-15 55.1 2.0 1.4e-14 54.3 2.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KDO29053.1 - 9.7e-06 24.8 2.6 6.8 5.5 0.0 5.8 3 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO29053.1 - 2.9e-05 22.9 6.3 0.0059 15.3 0.1 3.6 4 0 0 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KDO29053.1 - 0.00064 19.1 0.2 11 5.2 0.0 4.8 5 2 0 5 5 5 2 WD40-like domain PALB2_WD40 PF16756.5 KDO29053.1 - 0.13 11.2 4.0 4.8 6.0 0.1 3.6 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain FdsD PF11390.8 KDO29053.1 - 0.21 11.9 0.4 8.1 6.9 0.0 2.9 3 0 0 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD Gmad1 PF10647.9 KDO29053.1 - 0.63 9.7 5.5 3.8 7.2 0.5 3.3 2 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain WD40 PF00400.32 KDO29054.1 - 7.6e-13 48.7 12.8 0.065 14.1 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29054.1 - 1.7e-06 28.3 0.1 0.072 13.4 0.0 4.8 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KDO29054.1 - 1.4e-05 25.4 1.5 0.59 10.7 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain BBS2_Mid PF14783.6 KDO29054.1 - 0.00028 20.9 0.9 0.087 12.9 0.0 3.7 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KDO29054.1 - 0.0022 17.0 0.2 1.2 8.0 0.0 3.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KDO29054.1 - 0.014 14.7 0.8 1.5 8.1 0.1 2.6 1 1 0 2 2 2 0 WD40-like domain PQQ PF01011.21 KDO29054.1 - 0.033 14.1 1.8 0.54 10.3 0.2 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat Nucleoporin_N PF08801.11 KDO29054.1 - 0.051 12.3 0.1 1.4 7.5 0.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like PHTB1_N PF14727.6 KDO29054.1 - 0.057 12.8 0.3 3.7 6.8 0.2 2.8 1 1 2 3 3 3 0 PTHB1 N-terminus Cwf_Cwc_15 PF04889.12 KDO29054.1 - 3.2 7.4 14.7 5.5 6.7 14.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Anoctamin PF04547.12 KDO29055.1 - 9.9e-65 219.1 8.7 1.3e-64 218.7 8.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GAF PF01590.26 KDO29056.1 - 1.4e-32 113.1 0.0 9.7e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KDO29056.1 - 2.1e-22 79.9 0.0 7.9e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KDO29056.1 - 6.9e-18 65.2 0.0 3.2e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain Herpes_UL7 PF01677.16 KDO29056.1 - 0.17 11.6 0.3 0.3 10.8 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL7 like Glyco_transf_28 PF03033.20 KDO29058.1 - 4.4e-24 85.1 0.0 8e-17 61.6 0.0 3.0 2 2 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KDO29058.1 - 0.0018 18.6 0.7 0.029 14.7 0.0 2.9 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KDO29058.1 - 0.019 13.8 0.2 0.033 13.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Cyclin_N PF00134.23 KDO29059.1 - 5.8e-41 139.2 1.3 9.1e-38 128.9 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO29059.1 - 3.2e-27 95.0 4.4 5.3e-27 94.3 4.4 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain SCP2 PF02036.17 KDO29060.1 - 0.0048 17.4 0.0 0.22 12.1 0.0 2.4 2 0 0 2 2 2 1 SCP-2 sterol transfer family DUF3194 PF11419.8 KDO29060.1 - 0.14 12.5 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Pkinase PF00069.25 KDO29061.1 - 1.1e-59 202.0 0.0 1.5e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29061.1 - 1.8e-33 115.9 0.0 2.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29061.1 - 0.00046 19.6 0.0 0.0015 18.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Arm PF00514.23 KDO29061.1 - 0.65 10.1 4.3 13 6.0 0.2 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Sad1_UNC PF07738.13 KDO29062.1 - 1.3e-24 86.7 0.0 3.5e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal PBP1_TM PF14812.6 KDO29062.1 - 0.97 9.8 4.7 2.3 8.6 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 KDO29063.1 - 2.6e-59 200.7 0.0 3.1e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29063.1 - 2.2e-25 89.5 0.0 2.7e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29063.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO29063.1 - 0.038 13.9 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO29063.1 - 0.045 12.7 0.0 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO29063.1 - 0.22 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_1e PF01406.19 KDO29065.1 - 1e-95 320.6 0.0 1.7e-95 319.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KDO29065.1 - 1.5e-10 40.4 1.4 0.0011 17.8 0.0 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (M) RBM39linker PF15519.6 KDO29065.1 - 0.01 16.9 0.1 0.031 15.4 0.0 1.8 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein tRNA-synt_1 PF00133.22 KDO29065.1 - 0.02 13.2 0.0 0.061 11.6 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) EF-hand_1 PF00036.32 KDO29066.1 - 5.5e-120 382.3 25.9 4.4e-06 25.9 0.1 27.0 27 0 0 27 27 27 22 EF hand EF-hand_7 PF13499.6 KDO29066.1 - 7.4e-113 369.1 17.2 1.7e-09 38.0 0.0 14.9 15 0 0 15 15 14 14 EF-hand domain pair EF-hand_6 PF13405.6 KDO29066.1 - 5.1e-103 328.4 43.5 2.7e-05 23.7 0.0 27.5 27 0 0 27 27 27 23 EF-hand domain EF-hand_5 PF13202.6 KDO29066.1 - 1.9e-72 235.8 35.8 0.00029 20.2 0.0 23.7 23 0 0 23 23 23 18 EF hand EF-hand_8 PF13833.6 KDO29066.1 - 2.7e-65 216.1 31.0 1.3e-06 28.1 0.0 20.0 15 6 6 21 21 21 17 EF-hand domain pair Caleosin PF05042.13 KDO29066.1 - 2.6e-12 47.0 19.7 0.14 12.1 0.0 11.0 11 1 1 12 12 12 5 Caleosin related protein EF-hand_9 PF14658.6 KDO29066.1 - 4.4e-09 36.5 1.2 17 5.8 0.0 9.4 10 1 1 11 11 11 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO29066.1 - 2.6e-08 34.1 0.0 18 5.7 0.0 9.0 11 0 0 11 11 11 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KDO29066.1 - 0.00033 20.4 0.0 0.13 12.2 0.0 3.7 3 0 0 3 3 3 1 EF hand DUF2527 PF10736.9 KDO29066.1 - 0.071 13.0 0.3 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) C2-C2_1 PF11618.8 KDO29066.1 - 0.2 11.7 0.2 26 4.9 0.1 2.6 2 0 0 2 2 2 0 First C2 domain of RPGR-interacting protein 1 E3_UFM1_ligase PF09743.9 KDO29067.1 - 4.5e-66 223.3 0.0 1.8e-64 218.0 0.0 2.2 1 1 0 1 1 1 1 E3 UFM1-protein ligase 1 HTH_DeoR PF08220.12 KDO29067.1 - 0.056 13.2 0.1 1.6 8.5 0.0 3.1 4 0 0 4 4 4 0 DeoR-like helix-turn-helix domain FeoC PF09012.10 KDO29067.1 - 0.094 12.8 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator PGA2 PF07543.12 KDO29067.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Gal_Lectin PF02140.18 KDO29068.1 - 1e-29 102.8 3.1 7.7e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Galactose binding lectin domain Phage_CII PF05269.11 KDO29069.1 - 0.017 15.3 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage CII protein DUF501 PF04417.12 KDO29070.1 - 3.6e-38 130.5 0.1 4.6e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Autophagy_N PF03986.13 KDO29071.1 - 7.4e-39 132.8 0.0 1.1e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KDO29071.1 - 6.4e-19 68.3 0.8 1.8e-18 66.9 0.8 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KDO29071.1 - 1e-14 53.7 4.2 1.8e-14 52.9 4.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Hist_deacetyl PF00850.19 KDO29072.1 - 1.4e-68 231.7 0.0 2.8e-68 230.7 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain PHD PF00628.29 KDO29072.1 - 3.3e-08 33.3 5.4 3.3e-08 33.3 5.4 1.9 2 0 0 2 2 2 1 PHD-finger AP2 PF00847.20 KDO29072.1 - 0.0018 18.5 0.6 3 8.1 0.0 2.6 2 0 0 2 2 2 2 AP2 domain zf-HC5HC2H PF13771.6 KDO29072.1 - 0.098 12.9 0.3 0.28 11.4 0.3 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 KDO29072.1 - 0.31 11.2 4.5 0.083 13.1 1.0 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain Pkinase_Tyr PF07714.17 KDO29073.1 - 1e-29 103.6 0.0 1.9e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO29073.1 - 1.4e-24 86.8 0.0 2.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 KDO29073.1 - 3.3e-05 24.2 6.4 0.039 14.4 0.2 3.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29073.1 - 0.00048 19.8 6.2 0.025 14.4 0.6 2.9 1 1 1 2 2 2 2 Leucine rich repeat SKG6 PF08693.10 KDO29073.1 - 0.00054 19.3 1.4 0.001 18.4 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KDO29073.1 - 0.0019 17.9 3.4 0.0045 16.7 3.4 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Kdo PF06293.14 KDO29073.1 - 0.0058 16.0 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CD34_antigen PF06365.12 KDO29073.1 - 0.0061 16.2 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family NPDC1 PF06809.11 KDO29073.1 - 0.023 13.8 0.4 0.041 12.9 0.4 1.3 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) APH PF01636.23 KDO29073.1 - 0.027 14.4 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MLANA PF14991.6 KDO29073.1 - 0.044 14.1 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A LRR_6 PF13516.6 KDO29073.1 - 0.075 13.1 1.7 70 3.9 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeat EphA2_TM PF14575.6 KDO29073.1 - 0.1 13.5 0.0 0.24 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MaoC_dehydratas PF01575.19 KDO29074.1 - 1e-31 109.0 0.0 1.8e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KDO29074.1 - 4.2e-10 39.9 0.0 9.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ERp29_N PF07912.13 KDO29074.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain Methyltransf_31 PF13847.6 KDO29075.1 - 0.00015 21.6 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KDO29075.1 - 0.00096 18.7 0.0 0.0025 17.4 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KDO29075.1 - 0.0013 19.4 0.0 0.0023 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO29075.1 - 0.0095 15.4 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KDO29075.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KDO29075.1 - 0.049 14.3 0.0 0.077 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KDO29075.1 - 0.084 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase IQ PF00612.27 KDO29075.1 - 0.22 11.4 1.1 0.53 10.2 1.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Chitin_synth_1 PF01644.17 KDO29076.1 - 8.8e-50 168.9 0.1 1.3e-49 168.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KDO29076.1 - 1.3e-23 83.4 0.2 9.5e-23 80.6 0.1 2.2 2 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KDO29076.1 - 2.9e-12 46.9 1.3 5.1e-12 46.1 1.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KDO29076.1 - 5.1e-07 29.8 0.0 1.5e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 KDO29076.1 - 0.00071 19.5 0.0 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase N-terminal MIT PF04212.18 KDO29076.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain MacB_PCD PF12704.7 KDO29077.1 - 0.002 18.5 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 MacB-like periplasmic core domain RNase_PH PF01138.21 KDO29078.1 - 6e-35 120.6 0.0 1.5e-18 67.5 0.0 2.8 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO29078.1 - 1.6e-17 63.2 0.3 2.6e-11 43.4 0.0 2.7 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 KDO29078.1 - 8.1e-13 48.0 0.3 3.1e-12 46.1 0.4 1.9 2 0 0 2 2 2 1 KH domain S1 PF00575.23 KDO29078.1 - 0.0025 18.1 0.4 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 S1 RNA binding domain KH_2 PF07650.17 KDO29078.1 - 0.005 16.6 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 KH domain MtrH PF02007.18 KDO29080.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit EcoRII-N PF09217.10 KDO29083.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal bZIP_2 PF07716.15 KDO29083.1 - 1.3 9.2 8.3 0.4 10.8 5.2 1.8 2 0 0 2 2 2 0 Basic region leucine zipper PAP2 PF01569.21 KDO29084.1 - 1.2e-18 67.2 2.4 2.3e-18 66.2 2.4 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KDO29084.1 - 0.0064 16.2 9.6 0.016 14.9 0.9 2.9 2 1 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.6 KDO29084.1 - 0.064 13.8 0.7 0.48 11.0 0.7 2.4 1 1 0 1 1 1 0 PAP2 superfamily C-terminal HECT PF00632.25 KDO29085.1 - 3e-81 273.3 0.0 4e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) fn3 PF00041.21 KDO29085.1 - 8.8e-13 48.4 0.0 1.1e-05 25.7 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain WW PF00397.26 KDO29085.1 - 0.00019 21.5 1.5 0.00019 21.5 1.5 1.9 2 0 0 2 2 2 1 WW domain Aminotran_1_2 PF00155.21 KDO29086.1 - 2e-68 231.2 0.0 2.3e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KDO29086.1 - 3.1e-07 30.0 0.1 7.4e-07 28.7 0.0 1.5 1 1 0 2 2 2 1 Beta-eliminating lyase Aminotran_3 PF00202.21 KDO29086.1 - 3.3e-06 26.0 0.0 1.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-III Aminotran_5 PF00266.19 KDO29086.1 - 0.00011 21.3 0.0 0.00027 20.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V SHMT PF00464.19 KDO29086.1 - 0.00032 19.4 0.0 0.0066 15.1 0.0 2.5 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Cys_Met_Meta_PP PF01053.20 KDO29086.1 - 0.0035 15.9 0.0 0.0053 15.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KDO29086.1 - 0.0039 16.6 0.4 0.0078 15.6 0.4 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HATPase_c_5 PF14501.6 KDO29086.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Flg_hook PF02120.16 KDO29086.1 - 0.059 13.3 0.0 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK NUC153 PF08159.12 KDO29087.1 - 0.13 12.1 0.9 0.32 10.8 0.9 1.6 1 0 0 1 1 1 0 NUC153 domain bZIP_1 PF00170.21 KDO29087.1 - 0.19 11.9 9.4 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 bZIP transcription factor Aldedh PF00171.22 KDO29088.1 - 1.9e-128 428.9 0.1 2.2e-128 428.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAD PF05557.13 KDO29089.1 - 9e-40 136.7 66.4 4.5e-38 131.1 66.4 2.1 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF4726 PF15855.5 KDO29089.1 - 2.2 8.6 5.2 1.7 8.9 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) Pox_A_type_inc PF04508.12 KDO29089.1 - 2.8 7.9 10.9 8.7 6.4 0.0 5.1 4 1 1 5 5 5 0 Viral A-type inclusion protein repeat Hydrolase_6 PF13344.6 KDO29090.1 - 1.4e-23 82.9 0.0 5e-23 81.1 0.0 1.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO29090.1 - 7.9e-19 67.5 0.1 2.9e-18 65.7 0.1 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 KDO29090.1 - 1.5e-05 25.1 0.3 0.18 11.9 0.0 3.2 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO29090.1 - 7.7e-05 23.1 0.2 0.26 11.5 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KDO29090.1 - 0.12 12.0 0.0 0.56 9.8 0.0 1.9 2 1 0 2 2 2 0 Mitochondrial PGP phosphatase GTP_EFTU PF00009.27 KDO29091.1 - 3.9e-49 166.8 0.0 7.2e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KDO29091.1 - 2.1e-42 143.6 1.5 4.9e-42 142.4 1.4 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KDO29091.1 - 1e-17 63.9 0.0 2.1e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KDO29091.1 - 2e-08 34.5 0.1 4.4e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO29091.1 - 1.8e-05 24.8 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KDO29091.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KDO29092.1 - 5.1e-54 182.5 0.0 2.4e-26 92.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO29092.1 - 5.4e-13 49.4 7.4 0.0029 17.5 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KDO29092.1 - 9e-12 44.9 9.1 1.9e-09 37.4 4.9 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO29092.1 - 1.2e-07 31.4 8.4 0.1 12.0 0.3 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO29092.1 - 3.6e-07 29.8 1.0 0.0013 18.5 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO29092.1 - 9.4e-07 29.5 11.3 1.1e-05 26.0 0.1 3.3 3 1 1 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 KDO29092.1 - 3.9e-06 26.9 3.1 0.0034 17.5 0.5 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO29092.1 - 2e-05 24.6 2.5 0.0099 15.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO29092.1 - 0.0001 22.7 0.1 0.2 12.0 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 KDO29092.1 - 0.00036 19.3 0.0 1.3 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KDO29092.1 - 0.0009 18.3 0.4 0.47 9.4 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KDO29092.1 - 0.0018 18.1 0.4 1.8 8.2 0.1 2.7 2 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KDO29092.1 - 0.0019 18.7 0.4 2.1 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KDO29092.1 - 0.0023 17.2 0.3 0.53 9.4 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 KDO29092.1 - 0.0031 17.7 0.5 8.7 6.7 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KDO29092.1 - 0.0039 17.6 0.1 4.2 7.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 KDO29092.1 - 0.0061 16.2 0.6 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO29092.1 - 0.0074 16.7 0.5 4.5 7.7 0.1 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO29092.1 - 0.011 15.5 0.9 3.1 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO29092.1 - 0.014 15.7 2.4 3.7 7.8 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KDO29092.1 - 0.02 15.0 4.1 0.43 10.6 0.4 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain KAP_NTPase PF07693.14 KDO29092.1 - 0.02 14.1 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 KDO29092.1 - 0.022 14.6 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KDO29092.1 - 0.029 14.3 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KDO29092.1 - 0.03 14.0 1.9 2 8.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 KDO29092.1 - 0.05 12.5 0.6 1 8.2 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.23 KDO29092.1 - 0.052 13.6 2.1 2.3 8.3 0.0 2.8 2 1 0 2 2 2 0 Dynamin family MukB PF04310.12 KDO29092.1 - 0.061 13.1 2.2 0.51 10.1 0.1 2.9 3 0 0 3 3 3 0 MukB N-terminal AAA_33 PF13671.6 KDO29092.1 - 0.098 12.8 0.1 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KDO29092.1 - 0.11 12.0 1.9 1.7 8.1 0.3 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF815 PF05673.13 KDO29092.1 - 0.12 11.5 0.2 1.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KDO29092.1 - 0.12 12.4 0.1 5.5 7.0 0.0 3.3 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KDO29092.1 - 0.16 11.2 1.1 0.77 9.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KDO29092.1 - 0.24 11.6 4.3 2.9 8.1 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 KDO29092.1 - 0.27 11.5 3.4 2.3 8.5 0.1 3.1 3 1 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KDO29092.1 - 0.35 10.4 0.8 23 4.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KDO29092.1 - 0.47 10.4 2.0 18 5.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain HLH PF00010.26 KDO29093.1 - 6.2e-08 32.5 1.1 1e-07 31.8 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 KDO29093.1 - 0.0041 17.1 0.0 0.086 12.8 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 KDO29093.1 - 0.0042 17.3 0.0 0.013 15.8 0.0 1.8 1 1 0 1 1 1 1 PAS fold Imm42 PF15593.6 KDO29093.1 - 0.0092 16.5 1.1 0.016 15.7 1.1 1.4 1 0 0 1 1 1 1 Immunity protein 42 PAS_9 PF13426.7 KDO29093.1 - 0.02 15.2 0.0 0.069 13.4 0.0 1.9 2 1 0 2 2 2 0 PAS domain PAS_3 PF08447.12 KDO29093.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 KDO29093.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain IQ PF00612.27 KDO29094.1 - 9e-07 28.2 31.6 0.0031 17.2 1.8 6.1 5 1 0 5 5 5 5 IQ calmodulin-binding motif Na_H_Exchanger PF00999.21 KDO29095.1 - 7.2e-23 81.0 32.9 1e-22 80.5 32.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DEC-1_N PF04625.13 KDO29095.1 - 0.88 8.5 3.1 1.4 7.8 3.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Gpi1 PF05024.15 KDO29096.1 - 1.2e-45 155.9 8.6 2e-45 155.2 8.6 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) polyprenyl_synt PF00348.17 KDO29097.1 - 1.7e-64 217.3 0.1 2.1e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KDO29097.1 - 0.021 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Svs_4_5_6 PF17381.2 KDO29097.1 - 0.19 12.7 0.0 0.38 11.7 0.0 1.4 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 PDDEXK_1 PF12705.7 KDO29099.1 - 5.6e-31 108.4 0.2 1e-30 107.5 0.2 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KDO29099.1 - 1.2e-05 25.5 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF83 UvrD_C PF13361.6 KDO29099.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KDO29099.1 - 0.0032 17.2 0.2 0.0085 15.8 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO29099.1 - 0.037 14.4 7.0 0.19 12.1 0.7 4.2 3 2 0 3 3 3 0 AAA ATPase domain Dna2 PF08696.11 KDO29099.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 DNA replication factor Dna2 AAA_33 PF13671.6 KDO29099.1 - 0.044 13.9 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Csa1 PF06023.12 KDO29099.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 LRR_6 PF13516.6 KDO29100.1 - 3.2e-18 64.1 16.9 0.00043 20.1 0.1 8.3 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_1 PF00036.32 KDO29100.1 - 1.3e-09 36.9 0.8 0.00092 18.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO29100.1 - 5e-08 33.3 0.1 1.9e-07 31.4 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO29100.1 - 6.4e-08 31.9 0.1 0.019 14.9 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain DUF4476 PF14771.6 KDO29100.1 - 1.4e-05 25.3 0.0 0.12 12.7 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) LRR_4 PF12799.7 KDO29100.1 - 3.5e-05 24.1 16.7 0.051 14.0 0.9 5.3 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) EF-hand_5 PF13202.6 KDO29100.1 - 0.00022 20.6 0.0 0.75 9.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO29100.1 - 0.00057 19.7 0.2 0.0018 18.1 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair LRR_1 PF00560.33 KDO29100.1 - 0.0016 18.7 9.8 20 6.2 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO29100.1 - 0.028 14.2 17.9 5.5 6.8 0.0 6.5 5 2 0 5 5 5 0 Leucine rich repeat Pre-PUA PF17832.1 KDO29102.1 - 5.8e-23 81.4 0.0 8.2e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KDO29102.1 - 2.9e-15 56.0 0.3 4.6e-15 55.3 0.3 1.3 1 0 0 1 1 1 1 PUA domain FSH1 PF03959.13 KDO29103.1 - 1.3e-37 129.6 0.0 1.5e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KDO29103.1 - 0.0056 16.5 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Lyase_1 PF00206.20 KDO29104.1 - 2e-90 303.3 0.0 2.7e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KDO29104.1 - 1.4e-22 80.2 0.4 3.9e-22 78.8 0.2 1.9 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF1481 PF07356.12 KDO29104.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Kinesin PF00225.23 KDO29105.1 - 1.7e-96 323.0 0.0 2.4e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO29105.1 - 2.8e-24 85.7 0.0 1.9e-22 79.8 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 KDO29105.1 - 0.046 14.0 0.1 0.35 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Kinesin_assoc PF16183.5 KDO29105.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Kinesin-associated Cep57_MT_bd PF06657.13 KDO29105.1 - 0.076 13.5 0.4 0.81 10.2 0.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Cys_Met_Meta_PP PF01053.20 KDO29106.1 - 3.7e-11 42.2 0.5 2.8e-10 39.3 0.2 2.5 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DUF640 PF04852.12 KDO29106.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF640) APG17 PF04108.12 KDO29107.1 - 4.2e-22 78.8 2.5 3.4e-15 56.0 0.8 2.1 2 0 0 2 2 2 2 Autophagy protein Apg17 CBFD_NFYB_HMF PF00808.23 KDO29108.1 - 1.5e-11 44.4 0.1 3.9e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trm5_N PF18093.1 KDO29108.1 - 0.16 11.9 0.8 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain LRR_8 PF13855.6 KDO29109.1 - 4.7e-08 32.7 4.1 2.1e-07 30.6 0.0 3.8 4 2 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 KDO29109.1 - 2.2e-06 27.9 3.6 0.0011 19.4 0.0 4.6 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29110.1 - 1.6e-13 50.2 7.0 2.5e-12 46.3 0.4 3.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO29110.1 - 6.7e-11 42.3 8.2 5.4e-05 23.5 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO29110.1 - 0.0025 17.3 0.0 0.16 11.4 0.0 2.3 1 1 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KDO29110.1 - 0.91 9.7 5.5 2.1 8.6 1.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KDO29111.1 - 2.5e-07 30.4 0.5 2.5e-07 30.4 0.5 3.8 2 2 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO29111.1 - 3.5e-05 24.1 9.9 0.0083 16.5 0.1 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO29111.1 - 0.3 11.2 3.4 26 5.2 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KDO29111.1 - 8 7.4 6.2 72 4.5 0.3 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat T3SS_needle_F PF09392.10 KDO29112.1 - 0.054 13.7 0.2 0.054 13.7 0.2 3.9 5 1 1 6 6 6 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF NPV_P10 PF05531.12 KDO29112.1 - 1.3 9.6 10.6 1.7 9.2 0.1 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PAP2 PF01569.21 KDO29113.1 - 1.1e-05 25.2 4.4 3.3e-05 23.7 1.4 2.8 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KDO29113.1 - 0.023 14.8 0.0 0.023 14.8 0.0 2.3 2 1 1 3 3 3 0 Divergent PAP2 family RskA PF10099.9 KDO29113.1 - 0.17 12.2 13.6 1.3 9.3 8.9 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AAA_33 PF13671.6 KDO29114.1 - 3e-12 46.9 0.0 1.2e-11 45.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KDO29114.1 - 9.8e-06 25.2 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 KDO29114.1 - 0.0034 17.7 0.1 0.022 15.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO29114.1 - 0.004 16.9 0.5 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO29114.1 - 0.0042 17.6 0.0 0.015 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO29114.1 - 0.0055 17.1 0.6 0.02 15.2 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF3326 PF11805.8 KDO29114.1 - 0.015 14.2 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) PEPCK_ATP PF01293.20 KDO29114.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_5 PF07728.14 KDO29114.1 - 0.024 14.6 0.0 0.095 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.12 KDO29114.1 - 0.028 14.3 1.6 0.26 11.1 1.6 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KDO29114.1 - 0.029 13.7 0.4 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KDO29114.1 - 0.043 13.2 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KDO29114.1 - 0.066 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase tRNA_lig_CPD PF08302.11 KDO29114.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain AAA PF00004.29 KDO29114.1 - 0.15 12.5 0.0 0.61 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Yae1_N PF09811.9 KDO29115.1 - 1.2e-14 53.8 5.6 1.8e-14 53.1 5.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal C2 PF00168.30 KDO29118.1 - 0.0055 17.0 0.2 4.5 7.6 0.1 3.4 3 0 0 3 3 3 1 C2 domain DUF4460 PF14687.6 KDO29118.1 - 0.12 12.5 0.1 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) Glycos_transf_1 PF00534.20 KDO29119.1 - 0.00014 21.5 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO29119.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tyr_Deacylase PF02580.16 KDO29120.1 - 7.7e-25 88.1 0.0 8.9e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase tRNA_edit PF04073.15 KDO29121.1 - 3.3e-10 40.1 2.0 1.1e-09 38.4 0.2 2.4 2 1 0 2 2 2 1 Aminoacyl-tRNA editing domain Ank_2 PF12796.7 KDO29122.1 - 9.5e-20 71.0 0.1 4.8e-12 46.3 0.0 3.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29122.1 - 1.5e-18 64.9 0.3 0.018 15.6 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO29122.1 - 3.6e-16 58.8 1.4 0.00011 22.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat FYVE PF01363.21 KDO29122.1 - 4.9e-16 58.6 8.1 7.8e-16 58.0 8.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 KDO29122.1 - 1.2e-14 54.1 2.8 0.0006 20.1 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29122.1 - 5.5e-12 45.9 1.1 1e-06 29.1 0.0 4.6 2 2 4 6 6 6 1 Ankyrin repeats (many copies) FYVE_2 PF02318.16 KDO29122.1 - 0.075 13.2 0.8 0.15 12.3 0.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Pox_D3 PF04580.13 KDO29122.1 - 0.16 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein MOR2-PAG1_N PF14222.6 KDO29123.1 - 3.1e-05 23.2 8.7 0.02 13.9 8.7 2.3 1 1 0 1 1 1 1 Cell morphogenesis N-terminal HEAT PF02985.22 KDO29123.1 - 0.54 10.7 0.0 0.54 10.7 0.0 4.7 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 KDO29123.1 - 2.4 8.6 9.9 0.77 10.2 0.1 5.0 5 1 0 5 5 5 0 HEAT repeats fn3 PF00041.21 KDO29124.1 - 0.00073 19.8 0.0 0.00096 19.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Interfer-bind PF09294.10 KDO29124.1 - 0.017 15.4 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III MIF4G PF02854.19 KDO29125.1 - 2.4e-34 118.9 0.1 4.6e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 KDO29125.1 - 4.8e-25 87.8 0.2 2.5e-10 40.3 0.0 4.0 4 0 0 4 4 4 2 MA3 domain MAPEG PF01124.18 KDO29127.1 - 3.7e-17 62.5 1.2 4.6e-17 62.1 1.2 1.1 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 KDO29128.1 - 4.5e-17 62.2 6.9 6.1e-17 61.7 6.9 1.1 1 0 0 1 1 1 1 MAPEG family CBM9_1 PF06452.11 KDO29129.1 - 2.9e-07 30.6 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 KDO29129.1 - 0.0013 18.5 0.2 0.0025 17.5 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate-binding family 9 CHCH PF06747.13 KDO29130.1 - 2e-07 31.0 4.0 2.7e-07 30.5 4.0 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KDO29130.1 - 0.00053 19.7 1.1 0.00072 19.2 1.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KDO29130.1 - 0.021 15.1 4.4 0.055 13.8 4.2 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KDO29130.1 - 0.027 14.8 4.7 0.42 11.0 0.3 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KDO29130.1 - 0.13 12.3 5.1 0.2 11.7 5.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Gp_dh_C PF02800.20 KDO29132.1 - 4.4e-13 49.1 0.0 5.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain RII_binding_1 PF10522.9 KDO29132.1 - 0.06 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RII binding domain CbiC PF02570.15 KDO29133.1 - 0.09 12.4 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Precorrin-8X methylmutase ALS_ss_C PF10369.9 KDO29135.1 - 3e-15 56.2 0.0 1e-14 54.4 0.0 1.9 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KDO29135.1 - 3.5e-08 33.1 0.3 9.7e-08 31.7 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 KDO29135.1 - 1.4e-05 24.8 0.0 3.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain DUF1775 PF07987.11 KDO29136.1 - 1.4e-30 106.5 0.1 2.9e-30 105.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unkown function (DUF1775) LRR_6 PF13516.6 KDO29137.1 - 2.2e-20 70.9 25.2 0.0022 17.9 0.0 8.6 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 KDO29137.1 - 4.3e-10 38.7 8.7 2.2 9.2 0.0 7.8 7 0 0 7 7 7 2 Leucine Rich Repeat p25-alpha PF05517.12 KDO29137.1 - 1.4e-05 25.3 0.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 2 p25-alpha AMPK1_CBM PF16561.5 KDO29137.1 - 0.00013 22.2 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase LRR_8 PF13855.6 KDO29137.1 - 0.00013 21.7 22.3 0.26 11.1 1.2 5.3 4 3 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KDO29137.1 - 0.00016 22.0 16.4 6.3 7.4 0.1 5.4 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) zf-C3HC4_4 PF15227.6 KDO29138.1 - 9.8e-09 35.2 5.9 9.8e-09 35.2 5.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO29138.1 - 2.8e-08 33.6 4.2 5.4e-08 32.7 0.7 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO29138.1 - 3.8e-07 29.9 5.0 8.1e-07 28.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO29138.1 - 5.1e-07 29.4 6.1 5.1e-07 29.4 6.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO29138.1 - 5.3e-07 29.9 7.1 5.3e-07 29.9 7.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO29138.1 - 2.3e-05 24.1 6.6 2.6e-05 24.0 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO29138.1 - 5.4e-05 22.8 1.3 0.00073 19.2 0.2 3.1 3 1 0 3 3 3 1 RING-like zinc finger zf-RING_6 PF14835.6 KDO29138.1 - 0.00085 19.1 2.9 0.0018 18.1 2.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KDO29138.1 - 0.0018 18.2 4.8 0.0036 17.2 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KDO29138.1 - 0.0019 18.0 1.6 0.0035 17.1 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KDO29138.1 - 0.023 14.6 6.8 0.039 13.8 6.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO29138.1 - 0.023 15.0 5.9 0.1 12.9 5.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KDO29138.1 - 0.14 12.2 1.3 0.28 11.2 1.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-WRNIP1_ubi PF18279.1 KDO29138.1 - 0.17 12.6 2.5 0.63 10.8 1.4 2.4 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Ogr_Delta PF04606.12 KDO29138.1 - 0.18 11.8 0.5 0.18 11.8 0.5 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 KDO29138.1 - 0.39 10.9 4.2 0.21 11.7 1.5 1.9 2 0 0 2 2 2 0 Zinc ribbon domain PX PF00787.24 KDO29139.1 - 1.9e-07 31.0 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 PX domain SMC_N PF02463.19 KDO29140.1 - 1.9e-68 230.2 2.0 2.9e-68 229.6 2.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KDO29140.1 - 6.4e-22 78.1 0.1 2.1e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KDO29140.1 - 3.4e-15 57.1 0.0 3.4e-15 57.1 0.0 5.4 2 2 1 4 4 2 1 AAA domain AAA_21 PF13304.6 KDO29140.1 - 2.1e-12 47.5 1.1 2.8e-05 24.1 0.2 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO29140.1 - 9.4e-07 28.9 11.9 1.5e-05 24.9 1.1 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO29140.1 - 5.1e-05 22.9 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.21 KDO29140.1 - 0.0032 17.1 16.6 0.0032 17.1 16.6 5.3 2 2 3 5 5 5 1 Intermediate filament protein ABC_tran PF00005.27 KDO29140.1 - 0.0048 17.4 11.3 0.34 11.4 0.0 4.5 3 2 0 3 3 3 2 ABC transporter DUF3450 PF11932.8 KDO29140.1 - 0.0056 16.0 11.4 0.0056 16.0 11.4 6.8 4 2 3 7 7 7 2 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 KDO29140.1 - 0.035 14.6 0.4 0.035 14.6 0.4 9.2 6 3 4 10 10 9 0 Nucleopolyhedrovirus P10 protein SOGA PF11365.8 KDO29140.1 - 0.1 13.7 0.2 0.1 13.7 0.2 6.3 5 2 2 8 8 7 0 Protein SOGA APG6_N PF17675.1 KDO29140.1 - 0.3 11.6 81.8 0.39 11.3 6.3 7.1 2 2 4 7 7 7 0 Apg6 coiled-coil region FPP PF05911.11 KDO29140.1 - 2.5 6.2 53.0 0.3 9.2 17.4 3.7 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KDO29140.1 - 6.8 6.9 87.8 0.025 14.8 15.6 6.9 2 2 5 7 7 7 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KDO29140.1 - 7.5 5.3 78.9 0.081 11.8 8.9 6.5 2 2 5 7 7 7 0 Spc7 kinetochore protein fn3 PF00041.21 KDO29141.1 - 7.1e-144 468.6 103.1 3.3e-10 40.2 0.5 36.0 33 4 3 36 36 36 27 Fibronectin type III domain Calx-beta PF03160.14 KDO29141.1 - 1.8e-17 63.4 1.1 1.2e-06 28.6 0.3 5.7 5 0 0 5 5 5 2 Calx-beta domain fn3_2 PF16893.5 KDO29141.1 - 4.6e-12 45.9 5.6 0.01 15.9 0.0 12.3 16 0 0 16 16 16 2 Fibronectin type III domain TRP PF06011.12 KDO29141.1 - 2.5e-07 29.8 5.2 5.5e-07 28.7 5.2 1.5 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Interfer-bind PF09294.10 KDO29141.1 - 0.00015 22.0 0.0 67 3.9 0.0 8.4 11 0 0 11 11 11 0 Interferon-alpha/beta receptor, fibronectin type III EGF_2 PF07974.13 KDO29141.1 - 0.00046 20.5 10.0 0.0014 19.0 10.0 1.9 1 0 0 1 1 1 1 EGF-like domain Pur_ac_phosph_N PF16656.5 KDO29141.1 - 0.0016 19.0 76.1 0.43 11.2 0.0 21.6 24 4 1 25 25 25 2 Purple acid Phosphatase, N-terminal domain CUB PF00431.20 KDO29141.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 CUB domain EGF_Tenascin PF18720.1 KDO29141.1 - 3.9 7.6 5.8 12 6.1 5.8 1.9 1 0 0 1 1 1 0 Tenascin EGF domain PhoLip_ATPase_C PF16212.5 KDO29142.1 - 2.2e-71 240.6 12.0 2.2e-71 240.6 12.0 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO29142.1 - 3.1e-19 68.4 0.1 7.3e-19 67.2 0.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO29142.1 - 2.4e-12 47.6 0.8 6.2e-06 26.6 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO29142.1 - 3.6e-09 36.6 0.0 2.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO29142.1 - 1.1e-05 25.0 0.0 0.00019 21.0 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO29142.1 - 0.0015 18.3 0.0 0.0039 17.0 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO29142.1 - 0.014 15.8 0.0 7.3 6.9 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase POT1 PF02765.17 KDO29143.1 - 2.5e-12 46.8 0.0 4.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_C69 PF03577.15 KDO29144.1 - 2.2e-54 184.9 0.0 4.5e-54 183.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C69 CD20 PF04103.15 KDO29144.1 - 0.051 13.7 1.2 0.096 12.8 1.2 1.3 1 0 0 1 1 1 0 CD20-like family DUF3736 PF12540.8 KDO29145.1 - 2.9 8.0 7.6 1.7 8.8 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3736) E2F_TDP PF02319.20 KDO29146.1 - 8.6e-12 44.9 0.0 3.3e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KDO29146.1 - 1.6e-06 27.9 0.0 0.0029 17.5 0.0 3.0 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.11 KDO29146.1 - 0.0089 16.0 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain HTH_28 PF13518.6 KDO29146.1 - 0.26 11.4 1.3 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain E2F_TDP PF02319.20 KDO29147.1 - 3.3e-11 43.1 0.1 6.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KDO29147.1 - 0.00032 20.5 0.0 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Stm1_N PF09598.10 KDO29147.1 - 9.8 7.1 9.2 4.5 8.2 4.0 2.4 2 0 0 2 2 2 0 Stm1 SNF2_N PF00176.23 KDO29148.1 - 4.5e-64 216.4 0.0 9e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO29148.1 - 1.4e-18 67.3 0.0 3.9e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KDO29148.1 - 3.9e-12 45.9 0.0 9.4e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KDO29148.1 - 1.1e-06 28.8 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KDO29148.1 - 0.0017 18.1 0.0 0.0056 16.4 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 KDO29148.1 - 0.0023 16.9 0.0 0.0053 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF3145 PF11343.8 KDO29148.1 - 0.064 12.8 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Myosin_head PF00063.21 KDO29149.1 - 1.4e-208 694.4 0.0 1.8e-208 694.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CH PF00307.31 KDO29149.1 - 2.8e-12 46.8 0.2 6e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 KDO29149.1 - 0.0013 19.0 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin AAA_16 PF13191.6 KDO29149.1 - 0.0084 16.5 0.5 0.022 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO29149.1 - 0.022 15.0 0.0 0.08 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 KDO29149.1 - 0.039 13.8 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Zeta_toxin PF06414.12 KDO29149.1 - 0.085 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_6 PF12774.7 KDO29149.1 - 0.11 11.4 0.3 0.21 10.6 0.3 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region IQ PF00612.27 KDO29149.1 - 1.4 8.9 3.6 91 3.3 0.0 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif DUF1075 PF06388.11 KDO29150.1 - 0.084 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Birna_VP3 PF01767.16 KDO29151.1 - 0.0076 16.4 1.4 0.31 11.1 1.7 2.3 1 1 1 2 2 2 2 Birnavirus VP3 protein TipAS PF07739.13 KDO29151.1 - 0.091 13.3 4.4 6.1 7.4 0.4 2.7 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain DUF2239 PF09998.9 KDO29151.1 - 0.1 12.4 1.7 0.25 11.1 1.1 2.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2239) FKBP_C PF00254.28 KDO29152.1 - 7.3e-61 202.5 0.0 9.5e-31 106.0 0.0 2.1 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase fn3 PF00041.21 KDO29153.1 - 1.4e-155 506.0 98.0 1.6e-09 37.9 0.0 37.4 36 2 1 37 37 37 25 Fibronectin type III domain PAN_1 PF00024.26 KDO29153.1 - 1.2e-20 73.3 22.2 4.4e-08 33.0 1.5 5.2 4 1 1 5 5 5 4 PAN domain Laminin_G_3 PF13385.6 KDO29153.1 - 2.8e-14 53.5 0.4 2.8e-14 53.5 0.4 4.7 5 0 0 5 5 5 1 Concanavalin A-like lectin/glucanases superfamily PAN_4 PF14295.6 KDO29153.1 - 3.6e-11 42.8 31.3 0.00081 19.3 4.7 5.2 5 0 0 5 5 4 4 PAN domain Calx-beta PF03160.14 KDO29153.1 - 2e-10 40.7 2.9 5.3e-07 29.7 0.1 5.4 5 0 0 5 5 5 1 Calx-beta domain fn3_2 PF16893.5 KDO29153.1 - 4.2e-05 23.6 18.0 2.9 8.1 0.0 11.4 13 0 0 13 13 12 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO29153.1 - 0.00063 20.3 79.1 3.3 8.3 0.2 19.0 21 1 0 21 21 19 4 Purple acid Phosphatase, N-terminal domain PapC_C PF13953.6 KDO29153.1 - 0.09 12.6 5.4 13 5.7 0.1 5.2 5 0 0 5 5 5 0 PapC C-terminal domain LGFP PF08310.11 KDO29153.1 - 0.14 12.7 1.4 3.9 8.1 0.8 3.9 2 0 0 2 2 2 0 LGFP repeat DUF2369 PF10179.9 KDO29153.1 - 0.45 10.9 19.4 34 4.9 0.0 10.8 15 0 0 15 15 15 0 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KDO29153.1 - 0.82 10.0 8.2 10 6.5 0.0 7.0 10 0 0 10 10 7 0 Interferon-alpha/beta receptor, fibronectin type III NosD PF05048.13 KDO29153.1 - 1.5 8.0 48.7 0.79 8.9 4.3 7.2 3 3 4 7 7 7 0 Periplasmic copper-binding protein (NosD) PAN_2 PF08276.11 KDO29153.1 - 1.6 8.9 25.2 2.3 8.4 3.1 4.8 4 0 0 4 4 4 0 PAN-like domain EGF PF00008.27 KDO29153.1 - 1.8 9.0 5.6 9.3 6.7 5.6 2.4 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 KDO29153.1 - 2.6 8.5 16.5 0.23 11.8 10.4 2.7 2 0 0 2 2 1 0 EGF-like domain TAFII28 PF04719.14 KDO29154.1 - 9.5e-26 89.7 0.1 1.3e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TetR_C_25 PF17933.1 KDO29154.1 - 0.056 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CDC45 PF02724.14 KDO29154.1 - 2.8 6.1 8.2 3.3 5.9 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_6 PF12774.7 KDO29155.1 - 5.8e-145 482.3 0.0 3.2e-144 479.9 0.0 2.3 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO29155.1 - 5.5e-133 443.9 1.9 5.5e-133 443.9 1.9 2.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KDO29155.1 - 8.4e-104 347.1 0.0 2.6e-103 345.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KDO29155.1 - 8.9e-100 333.3 0.0 6.3e-99 330.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO29155.1 - 1.2e-85 286.1 7.2 1.3e-85 286.0 0.9 3.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO29155.1 - 2.8e-71 238.8 0.1 5.7e-67 224.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KDO29155.1 - 7e-54 182.0 0.0 1.4e-53 181.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KDO29155.1 - 2.1e-49 168.4 10.7 3.8e-49 167.6 10.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KDO29155.1 - 2.6e-46 156.6 0.0 2.9e-41 140.3 0.0 3.2 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KDO29155.1 - 9.9e-26 90.3 0.0 2.8e-25 88.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO29155.1 - 7.4e-18 64.6 0.0 3e-17 62.7 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO29155.1 - 3.3e-17 62.8 0.0 0.00012 22.1 0.0 5.6 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KDO29155.1 - 0.0036 17.8 0.0 0.17 12.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KDO29155.1 - 0.0049 17.1 0.0 2 8.7 0.0 3.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KDO29155.1 - 0.028 14.8 0.1 5.5 7.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DUF853 PF05872.12 KDO29155.1 - 0.044 12.4 10.5 0.045 12.3 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Neuregulin PF02158.15 KDO29155.1 - 0.065 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Neuregulin intracellular region AAA PF00004.29 KDO29155.1 - 0.11 12.9 0.3 1.3 9.5 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO29155.1 - 0.51 10.7 2.6 6.2 7.2 0.0 3.8 4 0 0 4 4 3 0 AAA ATPase domain HMA PF00403.26 KDO29156.1 - 2.3e-11 43.9 0.2 2.7e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KDO29156.1 - 0.003 17.9 0.4 0.0055 17.0 0.4 1.5 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Peptidase_C2 PF00648.21 KDO29157.1 - 3.7e-59 200.2 0.0 5.5e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease C2 PF00168.30 KDO29157.1 - 2.7e-06 27.6 0.0 8.4e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 C2 domain WW PF00397.26 KDO29157.1 - 4.2e-06 26.7 0.8 1.1e-05 25.4 0.8 1.8 1 0 0 1 1 1 1 WW domain Calpain_III PF01067.22 KDO29157.1 - 1.5e-05 25.3 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III RNAse_A_bac PF18431.1 KDO29159.1 - 0.064 14.2 1.3 0.13 13.3 1.3 1.7 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain DS PF01916.17 KDO29159.1 - 0.084 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase Caps_synth_GfcC PF06251.11 KDO29159.1 - 0.11 12.1 1.5 0.21 11.2 1.5 1.5 1 0 0 1 1 1 0 Capsule biosynthesis GfcC HPP PF04982.13 KDO29159.1 - 0.14 12.4 0.6 7.9 6.7 0.0 2.2 2 0 0 2 2 2 0 HPP family EF_assoc_1 PF08355.12 KDO29160.1 - 0.14 11.8 0.1 2.3 7.8 0.1 2.7 3 0 0 3 3 3 0 EF hand associated APG6_N PF17675.1 KDO29161.1 - 0.05 14.1 0.7 0.11 13.1 0.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KDO29161.1 - 0.076 12.6 1.6 0.13 11.8 1.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 GST_C_3 PF14497.6 KDO29162.1 - 4.6e-14 52.4 0.0 7.3e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO29162.1 - 2.7e-08 34.0 0.0 5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KDO29162.1 - 8e-07 29.0 0.1 3.6e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO29162.1 - 0.00041 20.5 0.0 0.0008 19.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO29162.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DHC_N1 PF08385.12 KDO29164.1 - 9.1e-169 562.7 4.5 9.1e-169 562.7 4.5 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KDO29164.1 - 6.1e-150 498.7 0.1 2.2e-149 496.8 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO29164.1 - 2e-123 412.4 8.1 2e-123 412.4 8.1 4.5 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KDO29164.1 - 4.8e-86 287.4 1.7 4.8e-86 287.4 1.7 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KDO29164.1 - 3e-85 285.7 0.1 1.8e-84 283.1 0.1 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KDO29164.1 - 1.7e-84 283.6 0.0 6.7e-84 281.7 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KDO29164.1 - 1.9e-70 236.0 0.2 7.6e-65 217.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KDO29164.1 - 1e-53 181.5 0.0 2.4e-53 180.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KDO29164.1 - 2.2e-53 181.5 8.2 1.5e-51 175.5 10.1 2.6 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KDO29164.1 - 3e-41 140.3 0.0 2.5e-40 137.3 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KDO29164.1 - 2.8e-23 82.4 0.4 2.1e-22 79.6 0.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KDO29164.1 - 2.4e-22 79.4 0.0 3.4e-07 30.3 0.0 5.3 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KDO29164.1 - 4.4e-14 52.5 0.0 2.2e-13 50.2 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KDO29164.1 - 5.2e-10 39.7 1.2 0.0063 16.8 0.0 5.6 6 0 0 6 6 4 2 AAA domain AAA PF00004.29 KDO29164.1 - 6.5e-09 36.3 0.2 0.1 13.0 0.0 5.6 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO29164.1 - 8.1e-08 32.8 0.8 0.53 10.7 0.0 5.8 5 1 0 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 KDO29164.1 - 0.0016 18.9 0.0 0.41 11.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KDO29164.1 - 0.0017 18.3 0.2 0.61 10.0 0.0 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain Sigma54_activat PF00158.26 KDO29164.1 - 0.0046 16.7 0.1 1.1 8.9 0.0 3.1 3 0 0 3 3 2 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KDO29164.1 - 0.007 16.3 0.2 0.071 13.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 KDO29164.1 - 0.038 14.4 0.0 14 6.1 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 KDO29164.1 - 0.056 13.1 5.2 3.8 7.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 KDO29164.1 - 0.058 13.9 0.0 0.97 9.9 0.0 3.0 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 KDO29164.1 - 0.061 12.7 0.1 0.42 9.9 0.0 2.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_19 PF13245.6 KDO29164.1 - 0.065 13.6 1.2 96 3.3 0.0 4.2 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 KDO29164.1 - 0.086 11.9 0.9 2.2 7.3 0.1 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein ATPase PF06745.13 KDO29164.1 - 0.17 11.2 1.9 2.5 7.4 0.0 3.5 3 0 0 3 3 3 0 KaiC DASH_Duo1 PF08651.10 KDO29164.1 - 0.55 10.0 2.5 16 5.3 0.0 4.4 4 0 0 4 4 4 0 DASH complex subunit Duo1 AAA_33 PF13671.6 KDO29164.1 - 0.7 10.0 3.2 93 3.2 0.0 4.2 5 0 0 5 5 4 0 AAA domain UPF0242 PF06785.11 KDO29164.1 - 9.7 6.2 10.0 0.31 11.1 1.3 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KDO29165.1 - 0.0041 17.0 0.9 0.0061 16.5 0.9 1.3 1 1 0 1 1 1 1 Prefoldin subunit FixS PF03597.15 KDO29166.1 - 0.54 10.0 3.3 0.88 9.3 3.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Corona_S2 PF01601.16 KDO29166.1 - 8.9 4.7 8.8 9.9 4.5 8.8 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DRTGG PF07085.12 KDO29167.1 - 0.0018 18.0 0.1 0.0039 17.0 0.1 1.5 1 0 0 1 1 1 1 DRTGG domain LYRIC PF15686.5 KDO29171.1 - 0.041 13.5 0.2 0.041 13.4 0.2 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Chlam_PMP PF02415.17 KDO29175.1 - 1.8e-05 24.9 11.0 0.12 12.9 0.0 4.8 4 0 0 4 4 4 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 KDO29175.1 - 0.00014 21.7 1.7 0.00019 21.3 1.7 1.2 1 0 0 1 1 1 1 Right handed beta helix region TRP PF06011.12 KDO29176.1 - 0.00031 19.6 8.9 0.00031 19.6 8.9 2.0 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel EbsA PF17255.2 KDO29177.1 - 0.24 11.7 2.4 0.45 10.8 2.4 1.4 1 0 0 1 1 1 0 EbsA-like protein Rax2 PF12768.7 KDO29178.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Acetyltransf_14 PF03421.16 KDO29178.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase RskA PF10099.9 KDO29178.1 - 1.9 8.7 15.4 4.2 7.6 15.4 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4927 PF16279.5 KDO29179.1 - 0.1 13.6 0.8 0.1 13.6 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4927) DUF4604 PF15377.6 KDO29179.1 - 0.17 12.3 8.1 0.27 11.6 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) LRR_4 PF12799.7 KDO29180.1 - 0.012 16.0 0.1 1.2 9.7 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) HTH_Crp_2 PF13545.6 KDO29180.1 - 0.039 13.9 0.2 0.15 12.1 0.2 2.0 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Peptidase_C23 PF05379.11 KDO29180.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Carlavirus endopeptidase HOASN PF14515.6 KDO29180.1 - 0.16 12.4 2.5 2.3 8.7 0.1 2.9 3 0 0 3 3 3 0 Haem-oxygenase-associated N-terminal helices COPI_assoc PF08507.10 KDO29181.1 - 4.9e-05 23.4 7.8 6.4e-05 23.0 7.8 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3681 PF12442.8 KDO29181.1 - 0.45 11.0 7.5 0.085 13.3 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) DUF4337 PF14235.6 KDO29181.1 - 0.88 9.7 2.8 3.8 7.6 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) UAA PF08449.11 KDO29182.1 - 5.1e-43 147.4 13.3 6.1e-43 147.2 13.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KDO29182.1 - 2.6e-09 37.4 26.6 1.4e-06 28.6 11.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KDO29182.1 - 1.5e-08 34.4 10.0 2.7e-08 33.5 10.0 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 KDO29182.1 - 6.7e-06 25.3 2.2 6.7e-06 25.3 2.2 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Phage_holin_2_4 PF16082.5 KDO29182.1 - 0.18 11.5 1.8 0.2 11.4 0.1 2.1 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF373 PF04123.13 KDO29182.1 - 4.4 6.6 12.2 0.58 9.5 6.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) EbsA PF17255.2 KDO29183.1 - 1.7 9.0 6.4 2 8.7 3.0 2.4 2 0 0 2 2 2 0 EbsA-like protein DRTGG PF07085.12 KDO29184.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 DRTGG domain PRP1_N PF06424.12 KDO29186.1 - 9.1e-53 178.6 0.0 2e-52 177.5 0.0 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KDO29186.1 - 1.1e-23 81.9 43.7 0.00019 22.0 0.2 13.7 8 5 8 16 16 16 8 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29186.1 - 1.5e-18 67.1 7.4 8.1e-08 32.7 0.0 8.5 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO29186.1 - 1.4e-06 27.9 2.0 1.5 9.1 0.3 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29186.1 - 1.8e-06 28.5 5.2 0.022 15.4 2.7 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO29186.1 - 0.00015 21.9 0.1 49 4.6 0.0 7.1 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29186.1 - 0.00029 20.8 1.6 15 6.1 0.0 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat UPF0184 PF03670.13 KDO29186.1 - 0.16 12.4 0.6 0.53 10.7 0.6 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) zf-C2H2 PF00096.26 KDO29188.1 - 0.0021 18.4 0.0 0.0021 18.4 0.0 2.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type CENP-B_N PF04218.13 KDO29188.1 - 0.0031 17.1 0.1 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 KDO29188.1 - 0.0074 16.6 1.8 0.3 11.4 0.0 2.8 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.6 KDO29188.1 - 0.0074 16.3 0.1 0.14 12.2 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KDO29188.1 - 0.0074 16.4 0.5 0.0074 16.4 0.5 3.9 4 0 0 4 4 4 1 Helix-turn-helix domain zf-C2H2_4 PF13894.6 KDO29188.1 - 0.45 11.5 0.1 0.45 11.5 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger TFIIIC_delta PF12657.7 KDO29189.1 - 2.3e-10 40.7 0.1 3.3e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KDO29189.1 - 7.1e-05 22.7 0.5 0.00015 21.6 0.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PQQ_3 PF13570.6 KDO29189.1 - 0.0084 16.6 4.3 0.29 11.7 0.3 3.6 2 1 1 3 3 3 1 PQQ-like domain PNP_UDP_1 PF01048.20 KDO29189.1 - 0.033 13.4 0.1 0.31 10.2 0.0 2.2 1 1 1 2 2 2 0 Phosphorylase superfamily ANAPC4_WD40 PF12894.7 KDO29189.1 - 0.16 12.3 0.1 4.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3268 PF11672.8 KDO29189.1 - 0.16 12.3 1.0 0.39 11.0 1.0 1.6 1 0 0 1 1 1 0 zinc-finger-containing domain HalOD2 PF18547.1 KDO29189.1 - 0.44 10.5 2.9 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 Halobacterial output domain 2 ATP_bind_1 PF03029.17 KDO29190.1 - 2.7e-85 286.0 0.0 3.8e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SAE2 PF08573.10 KDO29190.1 - 1.8e-06 29.1 4.4 0.0011 20.1 1.1 4.2 2 2 1 3 3 2 2 DNA repair protein endonuclease SAE2/CtIP C-terminus CLP1_P PF16575.5 KDO29190.1 - 0.0007 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3450 PF11932.8 KDO29190.1 - 0.0049 16.2 1.5 0.0083 15.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) AAA_30 PF13604.6 KDO29190.1 - 0.0052 16.5 0.5 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KDO29190.1 - 0.0055 17.0 0.1 0.033 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO29190.1 - 0.006 17.1 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain CEP63 PF17045.5 KDO29190.1 - 0.012 15.5 1.5 0.018 14.9 1.5 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa AAA_24 PF13479.6 KDO29190.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO29190.1 - 0.027 14.9 0.9 0.37 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain CCDC144C PF14915.6 KDO29190.1 - 0.027 13.6 2.0 0.04 13.0 2.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region AAA_33 PF13671.6 KDO29190.1 - 0.037 14.2 0.9 0.13 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.6 KDO29190.1 - 0.071 13.0 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO29190.1 - 0.079 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO29190.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Striatin PF08232.12 KDO29190.1 - 0.21 12.2 9.3 0.5 10.9 9.3 1.7 1 1 0 1 1 1 0 Striatin family Fer4_NifH PF00142.18 KDO29190.1 - 1.5 8.2 3.0 1.2 8.5 0.1 2.2 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FUSC PF04632.12 KDO29190.1 - 4.7 5.6 6.4 6.5 5.2 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ArfGap PF01412.18 KDO29191.1 - 4.9e-25 87.9 1.0 7e-25 87.4 1.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 KDO29191.1 - 0.00046 20.3 1.6 0.00069 19.7 1.6 1.3 1 0 0 1 1 1 1 B-box zinc finger AAA_18 PF13238.6 KDO29192.1 - 2.3e-08 34.6 0.0 4.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO29192.1 - 8.9e-05 22.7 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KDO29192.1 - 0.00046 19.5 0.0 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KDO29192.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KDO29192.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO29192.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DnaB_C PF03796.15 KDO29192.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CPT PF07931.12 KDO29192.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RsgA_GTPase PF03193.16 KDO29192.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Cytidylate_kin PF02224.18 KDO29192.1 - 0.071 12.8 0.1 0.21 11.3 0.0 1.9 2 1 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 KDO29192.1 - 0.11 11.9 0.2 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KDO29192.1 - 0.15 12.0 0.1 0.75 9.7 0.0 2.2 3 0 0 3 3 3 0 Adenylylsulphate kinase Arm PF00514.23 KDO29193.1 - 0.00025 21.0 0.3 0.00082 19.3 0.1 1.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat zf-RVT PF13966.6 KDO29194.1 - 0.0014 19.3 0.9 0.0014 19.3 0.9 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Glu_cyclase_2 PF05096.12 KDO29198.1 - 8.5e-79 264.5 0.0 1e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase F-box PF00646.33 KDO29199.1 - 0.00092 19.0 0.0 0.007 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KDO29199.1 - 0.0028 17.5 0.2 0.024 14.5 0.2 2.7 2 0 0 2 2 2 1 F-box-like ROK PF00480.20 KDO29200.1 - 1.5e-60 205.2 1.2 1.9e-60 204.8 1.2 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 KDO29200.1 - 0.00018 21.1 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KDO29200.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 KDO29200.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Hexokinase RRM_1 PF00076.22 KDO29201.1 - 5.8e-35 119.0 0.0 6.5e-18 64.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO29201.1 - 3.2e-12 46.4 0.1 7.7e-05 22.7 0.0 3.0 3 2 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO29201.1 - 2.9e-06 27.2 0.0 0.0064 16.5 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KDO29201.1 - 0.00039 20.7 0.2 3.3 7.9 0.1 3.1 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM PF05172.13 KDO29201.1 - 0.0022 17.9 0.0 0.086 12.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KDO29201.1 - 0.11 12.6 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Endonuclease_NS PF01223.23 KDO29202.1 - 3.6e-59 200.3 0.0 4.6e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease HAUS4 PF14735.6 KDO29203.1 - 6.1e-29 101.4 0.4 8.3e-29 100.9 0.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 MOR2-PAG1_C PF14225.6 KDO29203.1 - 0.0022 17.9 1.3 0.057 13.3 0.8 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal ABC_tran_CTD PF16326.5 KDO29203.1 - 0.33 11.2 16.2 2.2 8.6 1.9 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 KDO29203.1 - 0.4 10.0 6.9 1.7 8.0 2.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KDO29203.1 - 0.55 9.3 3.8 0.74 8.8 3.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cob_adeno_trans PF01923.18 KDO29203.1 - 0.84 9.8 5.7 1.3 9.2 4.8 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF4140 PF13600.6 KDO29203.1 - 1.4 9.4 5.9 13 6.3 0.1 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Zip PF02535.22 KDO29204.1 - 9.4e-29 100.7 8.4 2.4e-28 99.4 8.4 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_3 PF07732.15 KDO29204.1 - 4.2e-12 46.1 1.1 1.1e-06 28.6 0.1 4.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KDO29204.1 - 2e-10 40.5 4.4 1.1e-09 38.1 4.4 2.1 1 1 0 1 1 1 1 Multicopper oxidase Fam20C PF06702.12 KDO29206.1 - 0.15 11.9 1.4 0.23 11.2 1.4 1.2 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 Ank_2 PF12796.7 KDO29207.1 - 1.7e-24 86.2 1.0 1.8e-12 47.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29207.1 - 2.4e-19 69.4 0.0 5.3e-08 33.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29207.1 - 3.3e-17 60.8 0.2 0.00048 20.4 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KDO29207.1 - 7.7e-17 61.1 1.5 1e-05 25.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO29207.1 - 3.7e-13 49.3 2.4 6.4e-05 23.2 0.1 4.4 5 0 0 5 5 5 3 Ankyrin repeat HTH_Tnp_Tc5 PF03221.16 KDO29207.1 - 3.1e-09 36.7 0.0 9.8e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 KDO29207.1 - 0.0052 17.4 0.6 2.5 8.8 0.1 2.8 3 0 0 3 3 3 1 Homeodomain-like domain Cro PF09048.10 KDO29207.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Cro Fe_dep_repress PF01325.19 KDO29207.1 - 0.052 13.8 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Put_DNA-bind_N PF06971.13 KDO29207.1 - 0.15 12.1 0.1 0.45 10.6 0.1 1.8 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Octopine_DH PF02317.17 KDO29208.1 - 1.7e-37 128.8 0.0 2.5e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain ApbA PF02558.16 KDO29208.1 - 0.00012 21.8 0.1 0.00019 21.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KDO29208.1 - 0.001 18.6 0.4 0.0051 16.4 0.4 1.8 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KDO29208.1 - 0.0013 19.2 0.1 0.0032 18.0 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KDO29208.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 KDO29208.1 - 0.0025 16.8 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase YjeF_N PF03853.15 KDO29208.1 - 0.022 14.6 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Pyr_redox PF00070.27 KDO29208.1 - 0.056 14.0 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KDO29208.1 - 0.059 12.6 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1640 PF07798.11 KDO29209.1 - 0.47 10.5 4.4 0.5 10.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Snapin_Pallidin PF14712.6 KDO29209.1 - 5.9 7.4 9.1 3.3 8.2 1.1 3.3 3 1 0 3 3 3 0 Snapin/Pallidin MSC PF09402.10 KDO29210.1 - 2.4e-05 23.9 17.2 4.1e-05 23.2 8.9 3.0 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain Kinesin PF00225.23 KDO29211.1 - 1.2e-80 271.0 0.0 1.5e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO29211.1 - 5.2e-22 78.4 0.0 8.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding EF-hand_6 PF13405.6 KDO29211.1 - 0.0094 15.8 0.0 0.04 13.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KDO29211.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 EF hand MA3 PF02847.17 KDO29212.1 - 1.2e-19 70.4 0.0 2.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KDO29212.1 - 9.2e-16 58.1 0.5 2.8e-15 56.6 0.3 1.9 2 0 0 2 2 2 1 MIF4G domain zf-UBP PF02148.19 KDO29213.1 - 8.2e-21 74.1 6.9 2.5e-20 72.6 6.9 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 KDO29213.1 - 6.1e-19 68.1 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 KDO29213.1 - 1.9e-07 31.3 8.0 1.9e-07 31.3 8.0 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO29213.1 - 7.6e-07 28.9 7.3 7.6e-07 28.9 7.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO29213.1 - 0.00011 21.8 3.1 0.00011 21.8 3.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO29213.1 - 0.00078 19.3 5.7 0.00078 19.3 5.7 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO29213.1 - 0.0015 18.5 5.7 0.0015 18.5 5.7 2.8 1 1 1 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO29213.1 - 0.0022 17.8 16.8 0.013 15.3 4.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 KDO29213.1 - 0.0042 17.2 10.7 0.0067 16.5 10.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus zf-rbx1 PF12678.7 KDO29213.1 - 0.012 15.9 7.8 0.012 15.9 7.8 2.4 1 1 1 2 2 2 0 RING-H2 zinc finger domain RRM_1 PF00076.22 KDO29213.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ZapB PF06005.12 KDO29213.1 - 0.04 14.4 9.5 0.049 14.1 6.9 2.4 1 1 0 1 1 1 0 Cell division protein ZapB HSBP1 PF06825.12 KDO29213.1 - 0.058 13.3 0.4 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 KfrA_N PF11740.8 KDO29213.1 - 0.27 11.9 10.3 1.5 9.6 0.9 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Spc7 PF08317.11 KDO29213.1 - 0.43 9.4 10.7 0.66 8.8 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Prok-RING_4 PF14447.6 KDO29213.1 - 1.2 9.1 22.9 0.42 10.5 5.4 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Cdh1_DBD_1 PF18196.1 KDO29213.1 - 1.6 9.1 6.6 2.9 8.2 2.2 2.9 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 bZIP_2 PF07716.15 KDO29213.1 - 2.1 8.5 9.6 2.2 8.4 2.3 3.1 1 1 2 3 3 3 0 Basic region leucine zipper WD40_alt PF14077.6 KDO29213.1 - 2.1 8.3 4.0 1.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif DivIC PF04977.15 KDO29213.1 - 6.2 6.7 10.5 9.3 6.1 4.4 2.4 1 1 0 2 2 2 0 Septum formation initiator zf-Sec23_Sec24 PF04810.15 KDO29213.1 - 6.9 6.8 7.8 21 5.3 4.6 3.0 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger CPSase_L_D2 PF02786.17 KDO29214.1 - 1.1e-89 299.5 0.0 5.8e-83 277.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KDO29214.1 - 2.2e-44 151.5 0.0 3.9e-43 147.5 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KDO29214.1 - 8.7e-44 148.4 0.0 3e-43 146.7 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 KDO29214.1 - 2e-38 131.4 0.0 5.6e-38 130.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KDO29214.1 - 3.1e-09 36.7 0.1 6.2e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KDO29214.1 - 5.3e-08 32.6 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Peptidase_C26 PF07722.13 KDO29214.1 - 0.00067 19.5 0.1 0.092 12.5 0.1 2.7 1 1 1 2 2 2 1 Peptidase C26 ATPgrasp_Ter PF15632.6 KDO29214.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KDO29214.1 - 0.011 15.5 0.0 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KDO29214.1 - 0.029 13.8 0.1 1.4 8.3 0.1 3.1 3 1 0 3 3 3 0 ATP-grasp domain ATP-grasp_3 PF02655.14 KDO29214.1 - 0.032 14.3 0.1 0.078 13.0 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp domain AA_kinase PF00696.28 KDO29216.1 - 1.4e-27 96.9 0.1 2.3e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KDO29216.1 - 8.3e-22 77.9 0.1 6.7e-21 75.0 0.1 2.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KDO29216.1 - 1e-10 42.0 0.0 2.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 KDO29216.1 - 0.027 14.6 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PRA1 PF03208.19 KDO29219.1 - 1.2e-18 67.1 0.5 1.6e-18 66.7 0.5 1.1 1 0 0 1 1 1 1 PRA1 family protein YIEGIA PF14045.6 KDO29219.1 - 0.00062 18.7 0.0 0.00083 18.3 0.0 1.1 1 0 0 1 1 1 1 YIEGIA protein PRA1 PF03208.19 KDO29220.1 - 5.2e-23 81.3 1.7 6.6e-23 80.9 1.7 1.1 1 0 0 1 1 1 1 PRA1 family protein DHHC PF01529.20 KDO29220.1 - 0.019 15.0 2.3 0.037 14.1 2.3 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Tmemb_9 PF05434.11 KDO29220.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 TMEM9 Baculo_11_kDa PF06143.11 KDO29220.1 - 0.45 10.1 3.1 0.19 11.3 0.3 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family PRA1 PF03208.19 KDO29221.1 - 0.011 15.4 2.9 0.038 13.6 3.0 1.7 1 1 0 1 1 1 0 PRA1 family protein FA_desaturase PF00487.24 KDO29221.1 - 0.017 15.0 0.7 0.019 14.8 0.7 1.0 1 0 0 1 1 1 0 Fatty acid desaturase YqzM PF14141.6 KDO29221.1 - 0.073 13.1 4.6 0.12 12.5 4.6 1.3 1 0 0 1 1 1 0 YqzM-like protein VirB3 PF05101.13 KDO29221.1 - 0.21 11.8 3.8 0.13 12.5 1.3 1.8 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein TBP PF00352.21 KDO29222.1 - 3.8e-47 158.1 0.0 2.2e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Peptidase_M26_N PF05342.14 KDO29222.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region PRA1 PF03208.19 KDO29224.1 - 1e-23 83.5 1.0 1.2e-23 83.3 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein Erv26 PF04148.13 KDO29224.1 - 0.033 14.0 2.3 0.1 12.4 2.6 1.8 2 1 0 2 2 2 0 Transmembrane adaptor Erv26 TadE PF07811.12 KDO29224.1 - 0.042 14.1 0.5 0.098 12.9 0.5 1.7 1 0 0 1 1 1 0 TadE-like protein HEAT PF02985.22 KDO29225.1 - 4.7e-09 35.7 30.6 0.13 12.6 0.1 10.9 11 0 0 11 11 11 4 HEAT repeat Cnd1 PF12717.7 KDO29225.1 - 2.4e-08 34.2 7.1 0.037 14.1 0.1 5.4 4 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KDO29225.1 - 8e-07 29.4 23.2 0.047 14.1 0.4 7.4 5 2 3 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO29225.1 - 4.7e-06 27.1 0.1 7.4 7.3 0.0 5.9 5 2 1 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KDO29225.1 - 1.5e-05 24.6 0.5 0.0083 15.7 0.0 4.3 5 1 0 5 5 5 1 CLASP N terminal TIP120 PF08623.10 KDO29225.1 - 6.5e-05 22.8 0.5 6.2 6.6 0.0 4.3 4 1 1 5 5 5 2 TATA-binding protein interacting (TIP20) Dopey_N PF04118.14 KDO29225.1 - 0.0019 17.4 0.3 0.011 14.9 0.1 2.3 2 0 0 2 2 2 1 Dopey, N-terminal Adaptin_N PF01602.20 KDO29225.1 - 0.0036 15.9 6.0 0.16 10.5 0.2 3.5 3 1 0 3 3 3 2 Adaptin N terminal region ParcG PF10274.9 KDO29225.1 - 0.011 15.8 1.3 4.1 7.5 0.1 3.7 4 1 1 5 5 5 0 Parkin co-regulated protein HEAT_EZ PF13513.6 KDO29225.1 - 0.022 15.2 39.6 0.071 13.6 0.1 9.9 9 2 3 12 12 11 0 HEAT-like repeat MMS19_C PF12460.8 KDO29225.1 - 7.2 5.6 12.3 7.6 5.5 0.1 4.9 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal DEK_C PF08766.11 KDO29226.1 - 0.026 14.4 1.8 0.075 13.0 1.8 1.8 1 0 0 1 1 1 0 DEK C terminal domain SRP-alpha_N PF04086.13 KDO29226.1 - 0.55 10.1 13.2 0.98 9.3 13.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CoA_transf_3 PF02515.17 KDO29227.1 - 2.1e-31 109.3 3.6 3.5e-19 69.2 0.2 3.3 2 2 1 3 3 3 3 CoA-transferase family III Ribosomal_L22 PF00237.19 KDO29228.1 - 2.9e-38 130.2 0.1 4.6e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e MutS_V PF00488.21 KDO29230.1 - 5.6e-73 245.0 0.0 2.7e-72 242.8 0.0 2.1 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.18 KDO29230.1 - 3.9e-34 118.5 0.3 8.6e-34 117.4 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KDO29230.1 - 8.5e-33 113.0 0.1 1.6e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KDO29230.1 - 1.9e-12 47.4 0.0 3.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KDO29230.1 - 4.6e-11 43.2 0.0 1.5e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain II BTRD1 PF17660.1 KDO29230.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 SNARE PF05739.19 KDO29230.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 SNARE domain Cupin_4 PF08007.12 KDO29231.1 - 1.1e-70 238.7 0.0 1.5e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KDO29231.1 - 1.2e-05 25.2 0.0 0.0024 17.7 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 KDO29231.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KDO29231.1 - 0.16 11.7 0.0 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Sugar_tr PF00083.24 KDO29232.1 - 4.1e-94 316.0 19.8 7.2e-94 315.2 19.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29232.1 - 3.6e-27 95.2 31.2 1.1e-17 64.0 8.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO29233.1 - 7.7e-106 354.6 18.9 8.8e-106 354.5 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO29233.1 - 2.3e-29 102.4 50.7 1.9e-24 86.3 26.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ADK PF00406.22 KDO29234.1 - 4.5e-14 52.8 0.0 3e-07 30.6 0.0 3.2 3 1 0 3 3 2 2 Adenylate kinase AAA_33 PF13671.6 KDO29234.1 - 3.6e-10 40.2 0.0 0.0041 17.3 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 KDO29234.1 - 1.5e-09 38.5 0.0 5.5e-05 23.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KDO29234.1 - 1.6e-08 35.1 0.8 0.00029 21.3 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.6 KDO29234.1 - 4.5e-08 33.6 0.0 0.0026 18.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KDO29234.1 - 7.9e-08 32.8 0.0 0.00036 21.0 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KDO29234.1 - 1.4e-07 31.9 0.1 0.024 14.9 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KDO29234.1 - 2.2e-07 31.2 0.0 0.0025 18.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KDO29234.1 - 5.5e-05 23.2 0.4 0.0038 17.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KDO29234.1 - 6.2e-05 23.0 0.0 0.3 11.0 0.0 3.1 3 0 0 3 3 2 2 NACHT domain IstB_IS21 PF01695.17 KDO29234.1 - 0.0001 22.1 0.0 0.0049 16.6 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO29234.1 - 0.00013 22.3 0.0 0.11 12.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 KDO29234.1 - 0.0014 18.3 0.6 1.9 8.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 KDO29234.1 - 0.0019 18.4 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_25 PF13481.6 KDO29234.1 - 0.0066 16.1 0.0 2.7 7.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KDO29234.1 - 0.0069 16.4 0.0 1.6 8.7 0.0 3.2 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAP206 PF12018.8 KDO29234.1 - 0.0093 15.5 0.0 1.5 8.3 0.0 3.3 4 0 0 4 4 3 1 Domain of unknown function ABC_tran PF00005.27 KDO29234.1 - 0.013 16.0 0.0 13 6.3 0.0 3.4 3 0 0 3 3 3 0 ABC transporter NB-ARC PF00931.22 KDO29234.1 - 0.017 14.4 0.0 1.6 7.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 KDO29234.1 - 0.018 14.3 0.0 1.5 8.1 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin RuvB_N PF05496.12 KDO29234.1 - 0.022 14.5 0.1 0.22 11.2 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain APS_kinase PF01583.20 KDO29234.1 - 0.024 14.5 0.2 0.26 11.2 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_24 PF13479.6 KDO29234.1 - 0.025 14.3 0.0 0.31 10.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KDO29234.1 - 0.033 14.2 0.0 13 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain YHS PF04945.13 KDO29234.1 - 0.054 13.6 0.0 19 5.4 0.0 3.9 4 0 0 4 4 4 0 YHS domain Cytidylate_kin PF02224.18 KDO29234.1 - 0.072 12.8 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Hydin_ADK PF17213.3 KDO29234.1 - 0.082 13.2 0.7 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain MMR_HSR1 PF01926.23 KDO29234.1 - 0.091 12.8 0.0 8.6 6.5 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Roc PF08477.13 KDO29234.1 - 0.11 12.7 0.1 19 5.5 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KDO29234.1 - 0.15 11.6 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region KTI12 PF08433.10 KDO29234.1 - 0.17 11.3 0.0 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 KDO29234.1 - 0.2 11.6 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 NTPase GCP_C_terminal PF04130.13 KDO29235.1 - 4.2e-18 65.9 4.7 4.2e-18 65.9 4.7 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal EST1_DNA_bind PF10373.9 KDO29236.1 - 4.6e-26 92.0 1.1 7.5e-26 91.2 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain RNase_Zc3h12a PF11977.8 KDO29236.1 - 7.1e-24 84.4 0.0 2.5e-23 82.6 0.0 1.9 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain EST1 PF10374.9 KDO29236.1 - 0.0009 19.9 1.2 0.14 12.8 0.0 2.8 2 1 0 2 2 2 1 Telomerase activating protein Est1 PRORP PF16953.5 KDO29236.1 - 0.009 15.6 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 Protein-only RNase P TPR_17 PF13431.6 KDO29236.1 - 0.012 15.9 0.6 0.034 14.5 0.6 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_6 PF13516.6 KDO29237.1 - 5.5e-06 26.0 10.6 0.65 10.2 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeat ComZ PF10815.8 KDO29237.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 ComZ ZapB PF06005.12 KDO29237.1 - 0.37 11.3 5.7 0.069 13.6 1.6 1.9 2 0 0 2 2 2 0 Cell division protein ZapB HSCB_C PF07743.13 KDO29237.1 - 1 9.9 4.8 2.7 8.6 4.8 1.7 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain ABC_tran_CTD PF16326.5 KDO29237.1 - 2.8 8.2 9.3 11 6.3 9.4 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain SlyX PF04102.12 KDO29237.1 - 4 8.1 13.1 1.1 9.9 4.2 3.5 2 1 1 3 3 3 0 SlyX SMC_N PF02463.19 KDO29238.1 - 4.5e-62 209.4 5.7 1.1e-32 113.3 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KDO29238.1 - 2.3e-25 89.2 0.0 5.6e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KDO29238.1 - 3.1e-13 50.7 15.2 3.1e-13 50.7 15.2 5.4 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 KDO29238.1 - 7.4e-11 42.4 7.5 1e-05 25.5 1.5 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO29238.1 - 1.6e-10 41.3 0.1 1.8e-08 34.5 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KDO29238.1 - 0.0018 18.0 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CtIP_N PF10482.9 KDO29238.1 - 0.0023 18.0 11.7 0.0023 18.0 11.7 4.5 4 1 1 5 5 5 1 Tumour-suppressor protein CtIP N-terminal domain DUF724 PF05266.14 KDO29238.1 - 0.0058 16.5 5.5 0.0058 16.5 5.5 5.7 4 1 2 6 6 6 1 Protein of unknown function (DUF724) ABC_tran PF00005.27 KDO29238.1 - 1.8 9.1 19.1 3.3 8.2 0.0 5.6 4 2 0 4 4 4 0 ABC transporter Band_7 PF01145.25 KDO29240.1 - 1.6e-19 70.6 0.2 2.2e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Amnionless PF14828.6 KDO29240.1 - 0.099 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless Hydrolase_4 PF12146.8 KDO29241.1 - 2.8e-24 85.7 0.2 7.5e-14 51.6 0.1 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO29241.1 - 2.7e-11 43.6 0.1 1.8e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO29241.1 - 1.6e-07 31.1 0.0 2.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KDO29241.1 - 1.1e-06 29.4 6.0 2.1e-05 25.3 3.2 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KDO29241.1 - 6.2e-05 22.9 0.1 0.092 12.5 0.0 2.7 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase TPR_17 PF13431.6 KDO29241.1 - 0.00093 19.4 0.3 0.0035 17.6 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat FSH1 PF03959.13 KDO29241.1 - 0.0015 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 KDO29241.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 KDO29241.1 - 0.02 15.0 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 KDO29241.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.14 KDO29241.1 - 0.06 12.6 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase DUF4919 PF16266.5 KDO29241.1 - 0.22 11.5 0.0 1.2 9.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) TPR_2 PF07719.17 KDO29241.1 - 0.72 10.1 6.8 15 6.0 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DSPc PF00782.20 KDO29242.1 - 3e-13 49.7 0.0 4.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO29242.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FYVE PF01363.21 KDO29243.1 - 2.5e-12 46.8 11.2 5e-12 45.8 11.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO29243.1 - 0.0034 17.6 6.3 0.0063 16.7 6.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger BclA_C PF18573.1 KDO29243.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 BclA C-terminal domain zf-RING_5 PF14634.6 KDO29243.1 - 2.9 7.9 11.7 5.2 7.1 11.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain RCC1 PF00415.18 KDO29244.1 - 7.1e-94 308.3 24.2 3.1e-14 53.3 0.1 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29244.1 - 6.7e-41 137.3 54.7 6.9e-10 38.5 0.3 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat ubiquitin PF00240.23 KDO29245.1 - 6.2e-18 64.3 0.0 1.3e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO29245.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO29245.1 - 0.00012 22.5 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO29245.1 - 0.00035 20.7 0.0 0.001 19.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO29245.1 - 0.0072 16.8 0.0 0.018 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TPH PF13868.6 KDO29246.1 - 3.1e-14 52.3 95.7 3.1e-14 52.3 95.7 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DDRGK PF09756.9 KDO29247.1 - 3.2e-45 154.0 3.7 3.2e-45 154.0 3.7 2.0 1 1 1 2 2 2 1 DDRGK domain FeoC PF09012.10 KDO29247.1 - 0.0016 18.5 0.1 0.068 13.3 0.0 2.4 2 0 0 2 2 2 1 FeoC like transcriptional regulator HTH_24 PF13412.6 KDO29247.1 - 0.1 12.2 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SpoIIIAH PF12685.7 KDO29247.1 - 0.3 10.9 5.7 0.44 10.3 5.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop53 PF07767.11 KDO29247.1 - 0.64 9.4 23.5 0.82 9.0 23.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LapA_dom PF06305.11 KDO29247.1 - 8.9 6.2 8.7 0.91 9.4 0.2 2.6 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FYVE PF01363.21 KDO29248.1 - 2.3e-14 53.3 15.5 5.4e-14 52.1 15.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO29248.1 - 0.00084 19.5 10.8 0.0016 18.7 10.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 KDO29248.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 GAF domain DUF2387 PF09526.10 KDO29248.1 - 0.064 13.4 1.4 0.27 11.4 1.4 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Complex1_LYR PF05347.15 KDO29249.1 - 3.6e-07 30.1 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO29249.1 - 0.078 13.7 0.3 0.13 13.1 0.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Aminotran_1_2 PF00155.21 KDO29250.1 - 2.3e-67 227.7 0.0 2.7e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KDO29250.1 - 2.5e-05 23.7 0.1 4.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KDO29250.1 - 0.00035 19.6 0.0 0.0013 17.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KDO29250.1 - 0.0012 18.2 2.4 0.0041 16.5 2.4 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KDO29250.1 - 0.0028 16.2 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Flg_hook PF02120.16 KDO29250.1 - 0.0067 16.3 0.0 0.16 11.8 0.0 3.0 4 0 0 4 4 4 1 Flagellar hook-length control protein FliK HATPase_c_5 PF14501.6 KDO29250.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Peptidase_M16_M PF16187.5 KDO29251.1 - 3.7e-64 216.7 0.0 5.8e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KDO29251.1 - 4.8e-39 133.7 0.2 1.6e-38 132.0 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO29251.1 - 7.5e-29 101.0 0.0 2.3e-20 73.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain CBM_1 PF00734.18 KDO29252.1 - 5e-15 55.2 8.1 7.3e-09 35.4 1.4 2.8 2 0 0 2 2 2 2 Fungal cellulose binding domain PT PF04886.12 KDO29252.1 - 1.5e-05 24.4 17.1 0.0001 21.7 17.1 2.2 1 1 0 1 1 1 1 PT repeat Trypan_PARP PF05887.11 KDO29252.1 - 1.8 8.6 11.6 3.3 7.7 11.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBM_1 PF00734.18 KDO29253.1 - 8.8e-13 48.0 8.4 2.4e-12 46.6 8.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.18 KDO29254.1 - 9e-10 38.3 6.0 2.8e-09 36.8 6.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain GIT_CC PF16559.5 KDO29256.1 - 6.6e-05 22.7 3.7 0.0015 18.4 0.9 3.4 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 KDO29256.1 - 0.0073 16.3 1.1 0.0073 16.3 1.1 6.0 5 1 1 6 6 6 1 TATA element modulatory factor 1 DNA binding LRR_9 PF14580.6 KDO29257.1 - 1.7e-07 30.9 0.0 2.8e-06 26.9 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KDO29257.1 - 0.0012 19.2 0.5 0.0082 16.5 0.2 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29257.1 - 0.0024 17.6 0.1 0.0061 16.3 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat DER1 PF04511.15 KDO29258.1 - 4.5e-47 160.5 9.1 5.1e-47 160.3 9.1 1.0 1 0 0 1 1 1 1 Der1-like family Methyltransf_16 PF10294.9 KDO29259.1 - 7.4e-14 51.9 0.0 9.3e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO29259.1 - 2.3e-07 30.5 0.1 4.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KDO29259.1 - 7.3e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO29259.1 - 0.00012 22.8 0.0 0.00021 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KDO29259.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 KDO29259.1 - 0.0014 19.3 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO29259.1 - 0.0034 16.8 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KDO29259.1 - 0.0076 15.9 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 KDO29259.1 - 0.083 12.7 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain RNA_pol_A_bac PF01000.26 KDO29260.1 - 3.5e-27 95.0 0.1 3.9e-26 91.6 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KDO29260.1 - 7.8e-22 76.5 0.0 1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_15 PF13459.6 KDO29260.1 - 0.069 13.9 0.1 0.069 13.9 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain TSKS PF15358.6 KDO29260.1 - 0.14 10.5 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Fer4_7 PF12838.7 KDO29260.1 - 0.25 12.0 6.7 0.1 13.2 1.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Atg14 PF10186.9 KDO29261.1 - 4.4e-17 62.2 0.1 1.4e-15 57.2 0.1 2.4 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 KDO29261.1 - 0.13 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Apg6 BARA domain FoP_duplication PF13865.6 KDO29262.1 - 5e-13 49.4 1.9 5e-13 49.4 1.9 2.5 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Lipase_GDSL_2 PF13472.6 KDO29263.1 - 0.00014 22.3 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO29263.1 - 0.048 13.6 0.0 0.28 11.1 0.0 2.2 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Adaptin_N PF01602.20 KDO29264.1 - 4.8e-89 299.3 3.1 6.5e-89 298.9 3.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 KDO29264.1 - 4.8e-24 84.6 0.0 1.8e-23 82.8 0.0 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 KDO29264.1 - 1.9e-07 31.3 0.4 9.3e-07 29.0 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KDO29264.1 - 0.00077 19.8 1.2 0.1 13.0 0.1 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KDO29264.1 - 0.0024 18.3 1.2 5.6 7.6 0.0 3.7 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KDO29264.1 - 0.029 14.6 0.4 0.81 10.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat RCC1 PF00415.18 KDO29265.1 - 1.2e-73 243.6 13.6 6.2e-14 52.4 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29265.1 - 2.6e-37 125.9 26.4 3.1e-06 26.8 0.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 KDO29265.1 - 4.7e-27 93.5 0.3 8.7e-06 25.6 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KDO29265.1 - 2.9e-25 88.0 20.3 3.8e-07 30.0 0.1 8.0 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO29265.1 - 1.5e-21 75.9 11.8 1.1e-05 25.5 0.0 7.5 7 0 0 7 7 7 5 Kelch motif SPRY PF00622.28 KDO29265.1 - 7.2e-20 71.3 0.0 1.5e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Kelch_3 PF13415.6 KDO29265.1 - 3.3e-18 65.5 3.5 0.00037 20.7 0.1 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO29265.1 - 7.5e-13 47.8 3.9 8.5e-05 22.1 0.6 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KDO29265.1 - 3e-12 46.0 8.4 0.00017 21.4 0.4 6.0 5 0 0 5 5 5 2 Kelch motif RCC1 PF00415.18 KDO29266.1 - 3e-64 213.4 13.5 3.4e-12 46.8 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KDO29266.1 - 2.9e-57 194.5 0.0 5.2e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KDO29266.1 - 6.6e-36 123.1 0.0 7.6e-15 55.1 0.0 4.6 4 0 0 4 4 4 4 SPRY domain RCC1_2 PF13540.6 KDO29266.1 - 3.1e-29 100.1 32.3 1e-09 37.9 0.4 8.5 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat FHA PF00498.26 KDO29266.1 - 5.9e-13 49.0 0.9 1.6e-12 47.6 0.9 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO29266.1 - 5.7e-10 39.4 0.0 2e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Vps62 PF06101.11 KDO29266.1 - 1.3e-07 30.4 0.0 2.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 UBA PF00627.31 KDO29266.1 - 2.3e-05 24.2 0.5 0.015 15.2 0.0 3.3 3 0 0 3 3 3 2 UBA/TS-N domain TFIID-31kDa PF02291.15 KDO29267.1 - 7.6e-40 135.8 0.7 1.2e-39 135.1 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO29267.1 - 0.00076 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KDO29267.1 - 0.0031 17.9 0.2 0.0056 17.0 0.2 1.4 1 0 0 1 1 1 1 CENP-S protein TFIID_30kDa PF03540.13 KDO29267.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.24 KDO29267.1 - 0.0055 17.1 0.1 0.012 16.0 0.1 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KDO29267.1 - 0.051 13.7 0.2 0.09 12.9 0.2 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold HSF_DNA-bind PF00447.17 KDO29268.1 - 2.4e-46 156.3 7.4 1.9e-23 82.9 0.1 2.3 2 0 0 2 2 2 2 HSF-type DNA-binding Pkinase PF00069.25 KDO29269.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29269.1 - 1.7e-32 112.7 0.0 2.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO29269.1 - 2.3e-11 44.1 0.2 5.8e-11 42.8 0.2 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KDO29269.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KDO29269.1 - 0.00012 22.5 1.3 0.00066 20.1 1.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain SnoaL_2 PF12680.7 KDO29269.1 - 0.00018 22.1 0.0 0.00053 20.6 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.23 KDO29269.1 - 0.0017 18.4 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4440 PF14534.6 KDO29269.1 - 0.026 14.9 0.5 0.33 11.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4440) Pkinase_fungal PF17667.1 KDO29269.1 - 0.034 12.9 0.0 0.034 12.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase TPR_11 PF13414.6 KDO29270.1 - 2e-07 30.6 7.5 0.049 13.3 0.4 3.9 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.17 KDO29270.1 - 1.2e-06 28.2 10.8 0.058 13.5 0.9 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO29270.1 - 0.00029 20.5 18.5 0.015 15.1 1.3 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29270.1 - 0.0013 19.3 7.6 1.3 10.1 0.2 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29270.1 - 0.3 11.4 7.1 0.36 11.1 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29270.1 - 1.5 9.2 9.9 57 4.3 0.3 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 KDO29274.1 - 4.5e-42 143.8 0.0 8.3e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO29274.1 - 9.9e-20 70.9 0.3 6e-19 68.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO29274.1 - 4.2e-07 30.1 0.0 9.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KDO29274.1 - 0.00081 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF4217 PF13959.6 KDO29274.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) zf-RING_2 PF13639.6 KDO29276.1 - 6.4e-12 45.6 8.3 1.5e-11 44.4 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO29276.1 - 7.3e-08 32.1 8.3 1.7e-07 31.0 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO29276.1 - 2.2e-07 31.1 8.8 6.3e-07 29.6 8.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KDO29276.1 - 6.9e-06 25.8 5.7 8.5e-06 25.5 4.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO29276.1 - 8.6e-06 25.5 7.2 2.2e-05 24.2 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO29276.1 - 2.7e-05 23.9 4.1 7.1e-05 22.6 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO29276.1 - 8.3e-05 22.5 6.8 0.00027 20.8 6.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KDO29276.1 - 0.00019 21.1 5.5 0.00041 20.0 5.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KDO29276.1 - 0.00062 19.3 8.6 0.0014 18.2 8.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO29276.1 - 0.0021 18.1 5.6 0.0074 16.3 5.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO29276.1 - 0.0027 17.7 4.7 0.0027 17.7 4.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger DUF3446 PF11928.8 KDO29276.1 - 0.027 14.8 2.6 0.027 14.8 2.6 3.5 3 1 0 3 3 3 0 Early growth response N-terminal domain zf-C3H2C3 PF17122.5 KDO29276.1 - 0.56 10.3 5.8 2.2 8.4 5.6 2.3 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KDO29276.1 - 8.2 6.7 7.8 43 4.4 7.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Sel1 PF08238.12 KDO29277.1 - 3.5e-21 75.2 6.4 1.6e-05 25.4 0.6 4.9 5 0 0 5 5 5 4 Sel1 repeat EKAL PF17986.1 KDO29277.1 - 0.29 11.2 4.7 10 6.3 0.1 2.8 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain Ank_4 PF13637.6 KDO29278.1 - 1.3e-13 51.2 1.4 3.2e-08 34.0 0.7 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO29278.1 - 1.2e-11 45.0 0.0 1.4e-09 38.4 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO29278.1 - 3e-09 36.9 1.1 4.1e-07 30.1 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29278.1 - 8e-08 32.0 2.3 7.4e-06 25.9 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KDO29278.1 - 3.7e-07 30.3 2.5 7.6e-06 26.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat SMC_N PF02463.19 KDO29279.1 - 2e-31 109.1 0.0 8.6e-31 107.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KDO29279.1 - 8.1e-13 48.7 0.1 3.8e-12 46.5 0.1 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KDO29279.1 - 1.4e-08 35.5 1.5 2e-07 31.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KDO29279.1 - 1.2e-05 25.3 0.0 0.04 13.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO29279.1 - 0.00017 21.3 0.0 0.00056 19.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KDO29279.1 - 0.0024 18.4 4.2 0.02 15.4 0.0 3.9 4 0 0 4 4 4 1 ABC transporter AAA_5 PF07728.14 KDO29279.1 - 0.034 14.1 0.9 1.9 8.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KDO29279.1 - 0.047 13.6 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KDO29279.1 - 0.052 14.0 1.0 0.33 11.4 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KDO29279.1 - 0.22 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain KxDL PF10241.9 KDO29279.1 - 0.32 11.3 21.1 0.64 10.3 0.4 5.8 5 1 0 5 5 5 0 Uncharacterized conserved protein DUF5320 PF17253.2 KDO29279.1 - 1.1 10.3 5.6 22 6.2 0.2 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5320) CEP19 PF14933.6 KDO29279.1 - 1.6 9.0 3.3 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 CEP19-like protein DUF1664 PF07889.12 KDO29279.1 - 7.3 6.7 14.0 12 5.9 1.1 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 KDO29280.1 - 5.9e-48 161.4 35.4 3.6e-14 53.1 0.5 6.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29280.1 - 5.9e-34 112.3 27.3 0.00016 21.9 0.1 12.2 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 KDO29280.1 - 2.6e-32 110.8 27.9 2.9e-07 30.9 0.5 8.7 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29280.1 - 5.3e-29 99.9 34.1 0.00018 21.7 0.1 9.9 2 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 KDO29280.1 - 4e-27 93.4 38.9 0.00042 20.6 0.3 10.8 11 1 1 12 12 12 8 Ankyrin repeat VWA_3_C PF18571.1 KDO29280.1 - 0.09 12.7 9.3 2.7 7.9 0.0 4.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain UPF0016 PF01169.19 KDO29280.1 - 0.76 10.2 5.5 0.27 11.6 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Ank_3 PF13606.6 KDO29281.1 - 0.002 18.5 0.0 0.026 15.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KDO29281.1 - 0.0027 18.0 0.0 1.2 9.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO29281.1 - 0.0028 18.2 0.1 0.0059 17.2 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29282.1 - 0.00096 19.7 0.2 0.16 12.6 0.0 1.7 1 1 1 2 2 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29282.1 - 0.0093 16.4 0.1 0.022 15.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KDO29282.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KDO29282.1 - 0.042 14.3 0.1 0.27 11.8 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeat FH2 PF02181.23 KDO29283.1 - 1.6e-53 182.2 3.8 1.6e-49 169.0 4.9 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain RUN PF02759.19 KDO29283.1 - 1.6e-08 34.6 0.0 5.3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 RUN domain CCDC53 PF10152.9 KDO29283.1 - 3.4e-08 34.1 0.0 3.4e-08 34.1 0.0 2.7 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex FYVE PF01363.21 KDO29283.1 - 2e-06 27.9 6.0 3.7e-06 27.0 6.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO29283.1 - 0.00079 19.6 2.7 0.00079 19.6 2.7 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger WH2 PF02205.20 KDO29283.1 - 0.0039 17.0 29.2 0.24 11.3 0.5 7.4 8 0 0 8 8 8 4 WH2 motif GOLD_2 PF13897.6 KDO29283.1 - 0.056 13.9 4.3 5.5 7.5 0.0 3.1 2 1 1 3 3 3 0 Golgi-dynamics membrane-trafficking RibD_C PF01872.17 KDO29286.1 - 0.049 13.4 0.1 0.052 13.4 0.1 1.0 1 0 0 1 1 1 0 RibD C-terminal domain Skp1_POZ PF03931.15 KDO29287.1 - 1.6e-21 76.3 0.1 2.7e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KDO29287.1 - 1.8e-12 47.2 0.1 3.6e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 KDO29287.1 - 9.4e-05 22.6 0.1 0.00081 19.6 0.1 2.0 1 1 0 1 1 1 1 BTB/POZ domain IFT46_B_C PF12317.8 KDO29287.1 - 0.033 13.9 0.1 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal WGR PF05406.15 KDO29288.1 - 1.3e-18 66.9 0.0 3.5e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 WGR domain WWE PF02825.20 KDO29288.1 - 6.2e-07 29.9 2.3 6.2e-07 29.9 2.3 1.9 2 0 0 2 2 2 1 WWE domain Topo_Zn_Ribbon PF08272.11 KDO29288.1 - 1.5 8.5 3.4 0.66 9.7 0.5 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like GTP_EFTU PF00009.27 KDO29290.1 - 3.7e-29 101.7 2.2 2.2e-27 95.9 2.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KDO29290.1 - 1.8e-11 44.1 0.0 6.5e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KDO29290.1 - 4.5e-10 39.6 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO29290.1 - 6.5e-09 35.5 0.2 1.9e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KDO29290.1 - 5.3e-07 29.6 0.0 1.8e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 KDO29290.1 - 2.4e-06 27.3 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KDO29290.1 - 4.2e-06 26.8 0.5 0.0018 18.2 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase IF2_N PF04760.15 KDO29290.1 - 0.0031 17.3 0.0 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.22 KDO29290.1 - 0.0084 15.7 0.0 0.062 12.9 0.0 2.4 3 0 0 3 3 3 1 Ras family Dynamin_N PF00350.23 KDO29290.1 - 0.018 15.1 0.0 0.092 12.8 0.0 2.0 1 1 1 2 2 2 0 Dynamin family HEAT PF02985.22 KDO29292.1 - 4.3e-35 116.7 34.1 0.00088 19.3 0.1 14.0 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 KDO29292.1 - 1.1e-28 99.4 19.9 3.9e-08 33.6 0.0 8.2 3 3 6 9 9 9 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO29292.1 - 1.4e-10 41.6 0.1 1.7 9.3 0.0 6.9 5 3 2 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO29292.1 - 8.2e-07 29.2 4.2 0.0002 21.4 0.1 4.5 2 2 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO29292.1 - 3.1e-06 27.6 29.2 0.019 15.5 0.3 9.6 8 2 4 12 12 11 3 HEAT-like repeat RTP1_C1 PF10363.9 KDO29292.1 - 0.00023 21.3 1.3 1.2 9.3 0.0 4.5 5 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KDO29292.1 - 0.00027 19.6 8.5 0.018 13.7 1.4 3.9 2 2 2 4 4 4 2 Adaptin N terminal region Ecm29 PF13001.7 KDO29292.1 - 0.0013 17.5 0.2 1.8 7.1 0.0 3.0 1 1 1 2 2 2 2 Proteasome stabiliser DRIM PF07539.12 KDO29292.1 - 0.081 11.2 1.7 0.89 7.8 0.2 2.8 2 1 1 3 3 3 0 Down-regulated in metastasis NblA PF04485.12 KDO29292.1 - 0.11 12.9 0.0 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA M11L PF11099.8 KDO29292.1 - 0.22 11.8 0.1 0.9 9.8 0.0 2.0 2 0 0 2 2 2 0 Apoptosis regulator M11L like Arm PF00514.23 KDO29292.1 - 0.9 9.7 12.9 6.2 7.0 0.1 6.3 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat zf-RING_2 PF13639.6 KDO29293.1 - 2.6e-10 40.5 8.4 2.6e-10 40.5 8.4 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO29293.1 - 1.4e-09 37.7 8.4 1.4e-09 37.7 8.4 2.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO29293.1 - 3.3e-07 29.9 4.4 7.7e-07 28.7 4.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO29293.1 - 2.4e-06 27.7 10.8 1.4e-05 25.3 10.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO29293.1 - 1.9e-05 24.5 6.5 1.9e-05 24.5 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KDO29293.1 - 2.7e-05 24.3 5.2 2.7e-05 24.3 5.2 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-ANAPC11 PF12861.7 KDO29293.1 - 0.0011 19.0 4.3 0.0074 16.3 4.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO29293.1 - 0.0027 17.7 2.7 0.0027 17.7 2.7 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO29293.1 - 0.0043 17.0 4.6 0.0043 17.0 4.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO29293.1 - 0.013 15.3 4.3 0.013 15.3 4.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KDO29293.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 KDO29293.1 - 0.28 11.6 3.5 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Ribosomal_S27e PF01667.17 KDO29293.1 - 0.4 10.4 2.9 0.8 9.5 2.9 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 ABC_membrane PF00664.23 KDO29294.1 - 9.8e-47 159.9 24.3 3.9e-28 98.9 10.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO29294.1 - 7.3e-39 133.4 0.0 1.2e-30 106.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO29294.1 - 1.6e-08 34.3 1.4 0.009 15.5 0.4 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO29294.1 - 6.3e-08 32.7 0.2 0.0031 17.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO29294.1 - 8.8e-07 29.3 0.1 0.062 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO29294.1 - 5.1e-06 26.1 0.8 0.064 13.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KDO29294.1 - 8.1e-06 26.0 1.0 0.0004 20.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KDO29294.1 - 3e-05 24.5 0.9 0.014 15.8 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KDO29294.1 - 6.3e-05 22.9 2.2 0.5 10.1 0.1 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KDO29294.1 - 8.9e-05 21.8 0.1 0.13 11.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KDO29294.1 - 0.00018 21.4 0.3 0.1 12.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KDO29294.1 - 0.0012 19.4 0.1 1.2 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KDO29294.1 - 0.0014 18.7 3.4 0.12 12.5 0.3 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_25 PF13481.6 KDO29294.1 - 0.0019 17.8 1.0 0.27 10.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KDO29294.1 - 0.0035 16.5 0.1 2.6 7.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KDO29294.1 - 0.004 16.5 0.8 1.5 8.1 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KDO29294.1 - 0.0046 15.9 0.5 1.8 7.4 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 KDO29294.1 - 0.0094 15.7 0.0 0.91 9.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KDO29294.1 - 0.01 15.6 1.7 3 7.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KDO29294.1 - 0.014 15.0 1.0 0.82 9.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KDO29294.1 - 0.056 14.0 0.3 8.5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO29294.1 - 0.057 12.9 0.2 9.7 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KDO29294.1 - 0.097 12.4 1.5 3.3 7.4 0.4 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KDO29294.1 - 0.098 11.8 0.3 17 4.5 0.0 2.8 3 1 1 4 4 4 0 NB-ARC domain AAA_33 PF13671.6 KDO29294.1 - 0.13 12.4 4.0 0.97 9.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 KDO29294.1 - 0.14 11.9 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KDO29294.1 - 0.16 11.9 0.2 8 6.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KDO29294.1 - 0.16 12.3 0.2 9.7 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 KDO29294.1 - 0.25 10.6 1.1 3.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin BTB_2 PF02214.22 KDO29295.1 - 1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KDO29295.1 - 1.8e-06 28.0 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KDO29295.1 - 0.091 13.0 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain ABC_tran PF00005.27 KDO29297.1 - 1.6e-50 171.2 0.0 1.3e-30 106.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO29297.1 - 1.8e-49 168.8 33.3 8.1e-31 107.7 15.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO29297.1 - 4.7e-10 39.3 3.6 0.15 11.4 0.0 4.2 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO29297.1 - 5.6e-07 29.6 0.1 0.03 14.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KDO29297.1 - 3.6e-06 27.2 0.2 0.00032 20.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KDO29297.1 - 6.8e-06 26.4 0.1 0.061 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO29297.1 - 9.1e-06 25.3 1.0 0.076 12.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO29297.1 - 3.6e-05 24.2 0.3 0.023 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KDO29297.1 - 7e-05 22.8 2.7 0.35 10.6 0.1 3.7 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KDO29297.1 - 0.00013 21.7 0.1 0.024 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO29297.1 - 0.00016 20.9 0.1 0.21 10.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KDO29297.1 - 0.00021 21.2 0.3 0.1 12.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KDO29297.1 - 0.001 19.2 2.0 0.12 12.4 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KDO29297.1 - 0.0011 19.5 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KDO29297.1 - 0.0035 16.4 0.0 2.8 6.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KDO29297.1 - 0.0045 16.4 0.9 1.5 8.1 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KDO29297.1 - 0.0053 15.7 0.5 1.9 7.3 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KDO29297.1 - 0.0093 15.6 0.2 0.76 9.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KDO29297.1 - 0.015 15.1 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KDO29297.1 - 0.022 14.5 1.1 7.7 6.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KDO29297.1 - 0.03 14.5 0.2 0.96 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO29297.1 - 0.034 14.7 0.1 9.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO29297.1 - 0.053 13.0 0.2 8.9 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO29297.1 - 0.11 12.9 0.0 10 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KDO29297.1 - 0.18 12.0 0.1 33 4.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KDO29297.1 - 0.26 10.5 1.0 3.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KDO29297.1 - 0.83 9.4 4.6 3.9 7.2 0.5 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TF_Zn_Ribbon PF08271.12 KDO29298.1 - 0.0071 15.8 3.6 0.11 12.0 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-HIT PF04438.16 KDO29298.1 - 0.12 12.3 1.0 0.12 12.3 1.0 2.7 2 1 0 2 2 2 0 HIT zinc finger PolC_DP2 PF03833.13 KDO29298.1 - 0.34 8.7 1.4 0.35 8.7 1.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_2 PF13240.6 KDO29298.1 - 0.59 9.9 11.7 5.7 6.8 0.7 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 KDO29298.1 - 1.9 8.1 8.3 3.9 7.2 0.3 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Nsp1_C PF05064.13 KDO29299.1 - 1.1e-18 67.1 3.2 1.1e-18 67.1 3.2 2.0 2 0 0 2 2 2 1 Nsp1-like C-terminal region LMBR1 PF04791.16 KDO29299.1 - 0.98 8.3 3.6 1.4 7.8 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4164 PF13747.6 KDO29299.1 - 1.4 9.3 6.3 1 9.7 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Snapin_Pallidin PF14712.6 KDO29299.1 - 2.6 8.5 8.6 3 8.3 0.6 2.6 2 1 0 2 2 2 0 Snapin/Pallidin BTB_2 PF02214.22 KDO29300.1 - 1.3e-23 83.1 0.3 1.5e-11 44.5 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain B12-binding PF02310.19 KDO29300.1 - 0.064 13.3 0.0 0.57 10.2 0.1 2.2 2 0 0 2 2 2 0 B12 binding domain Fibin PF15819.5 KDO29300.1 - 0.12 12.2 0.9 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Fin bud initiation factor homologue CheB_methylest PF01339.17 KDO29300.1 - 0.12 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 CheB methylesterase APG6_N PF17675.1 KDO29300.1 - 0.16 12.5 11.8 0.54 10.8 3.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 KDO29300.1 - 0.19 12.0 7.7 1.2 9.4 2.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 KDO29300.1 - 0.46 10.7 3.3 15 5.8 0.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KDO29300.1 - 1.4 8.9 7.8 4.5 7.3 0.7 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AATF-Che1 PF13339.6 KDO29300.1 - 4.1 8.1 8.8 21 5.8 8.8 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4140 PF13600.6 KDO29300.1 - 4.7 7.7 11.5 9.6 6.7 2.6 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BTB_2 PF02214.22 KDO29301.1 - 1.1e-11 44.9 0.0 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF2514 PF10721.9 KDO29301.1 - 0.0015 18.5 1.2 0.0025 17.8 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) BTB PF00651.31 KDO29301.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Lipase_GDSL_2 PF13472.6 KDO29302.1 - 1.7e-28 100.3 0.1 2e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO29302.1 - 4.2e-17 62.8 0.0 6.5e-17 62.2 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Patatin PF01734.22 KDO29303.1 - 2.5e-05 24.5 0.1 0.0013 19.0 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 KDO29304.1 - 5.4e-06 26.7 0.1 0.00023 21.4 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase zf-HIT PF04438.16 KDO29305.1 - 0.0022 17.8 17.4 0.11 12.4 1.8 2.4 2 1 0 2 2 2 2 HIT zinc finger Desulfoferrod_N PF06397.12 KDO29305.1 - 0.024 14.3 6.8 0.17 11.5 1.4 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Securin PF04856.13 KDO29305.1 - 0.084 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor TF_Zn_Ribbon PF08271.12 KDO29305.1 - 0.089 12.3 0.6 0.089 12.3 0.6 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding zf-CCHC_2 PF13696.6 KDO29305.1 - 1.3 8.9 9.8 8 6.4 2.8 3.1 2 1 0 2 2 2 0 Zinc knuckle Ank_2 PF12796.7 KDO29306.1 - 2.7e-31 108.0 0.2 7.6e-09 36.0 0.0 5.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) RasGEF PF00617.19 KDO29306.1 - 1.6e-30 106.6 0.0 2.9e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Ank_4 PF13637.6 KDO29306.1 - 7e-28 96.6 0.4 5.6e-09 36.4 0.1 6.8 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29306.1 - 8.3e-24 83.3 2.3 3.8e-06 27.1 0.1 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO29306.1 - 1.3e-21 76.0 5.6 0.0012 19.2 0.0 8.2 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KDO29306.1 - 5.4e-19 66.3 0.8 0.02 15.4 0.0 8.6 8 0 0 8 8 7 4 Ankyrin repeat PH PF00169.29 KDO29306.1 - 4.3e-13 49.7 1.1 7e-13 49.0 0.2 1.9 2 0 0 2 2 2 1 PH domain VPS9 PF02204.18 KDO29306.1 - 2.9e-05 24.2 0.0 7.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH_8 PF15409.6 KDO29306.1 - 0.0073 16.6 0.0 0.098 13.0 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PDZ PF00595.24 KDO29306.1 - 0.02 15.2 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KDO29306.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain SF-assemblin PF06705.11 KDO29307.1 - 6.2e-40 137.1 22.9 7.3e-40 136.9 22.9 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Prominin PF05478.11 KDO29307.1 - 0.027 12.5 12.1 0.002 16.2 6.2 1.7 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 KDO29307.1 - 0.037 14.1 4.2 0.24 11.4 0.0 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KDO29307.1 - 0.6 10.2 6.9 1.8 8.7 1.2 3.2 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TMPIT PF07851.13 KDO29307.1 - 7.1 5.8 9.9 0.67 9.1 1.7 2.1 1 1 2 3 3 3 0 TMPIT-like protein YlqD PF11068.8 KDO29307.1 - 7.8 6.9 12.5 0.45 10.9 2.6 3.0 2 1 1 3 3 3 0 YlqD protein Pkinase PF00069.25 KDO29308.1 - 3.8e-58 196.9 0.0 4.4e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29308.1 - 2e-26 92.9 0.0 2.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29308.1 - 7.9e-08 31.9 0.0 1.4e-06 27.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KDO29308.1 - 0.00025 21.0 0.2 0.007 16.3 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO29308.1 - 0.0024 17.3 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO29308.1 - 0.075 12.6 0.2 0.23 11.1 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KDO29308.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO29308.1 - 0.098 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KDO29308.1 - 0.25 10.2 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC2_membrane PF01061.24 KDO29309.1 - 1.2e-66 224.1 72.9 1.3e-39 135.8 27.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO29309.1 - 3e-28 99.0 0.0 8.2e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 KDO29309.1 - 1e-06 28.8 1.2 0.0091 15.9 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KDO29309.1 - 1.2e-06 28.6 2.3 0.036 13.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO29309.1 - 1.5e-06 28.7 0.1 0.042 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO29309.1 - 1.7e-06 27.6 3.3 0.018 14.8 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO29309.1 - 0.0005 20.3 1.3 0.74 10.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KDO29309.1 - 0.00097 18.5 2.1 0.055 12.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 KDO29309.1 - 0.00098 18.6 0.5 5.7 6.3 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KDO29309.1 - 0.0012 19.3 0.5 3.7 8.0 0.1 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 KDO29309.1 - 0.0017 17.5 56.1 0.002 17.3 26.3 3.5 2 2 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 KDO29309.1 - 0.0042 16.7 1.4 0.76 9.3 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO29309.1 - 0.0061 17.1 0.1 4.3 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain PDR_CDR PF06422.12 KDO29309.1 - 0.011 15.6 0.4 0.011 15.6 0.4 3.3 3 0 0 3 3 2 0 CDR ABC transporter MMR_HSR1 PF01926.23 KDO29309.1 - 0.014 15.5 2.8 0.93 9.6 0.2 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KDO29309.1 - 0.016 14.9 3.2 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO29309.1 - 0.039 14.3 1.0 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KDO29309.1 - 0.062 13.8 3.5 1.4 9.4 1.3 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO29309.1 - 0.095 12.9 0.5 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO29309.1 - 0.12 12.6 0.4 11 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KDO29309.1 - 0.15 11.4 0.3 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KDO29309.1 - 0.15 11.8 2.5 8.6 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KDO29309.1 - 0.23 11.4 1.5 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 KDO29309.1 - 0.23 11.4 0.4 6.7 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KDO29309.1 - 0.39 10.4 4.0 5.7 6.7 0.7 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KDO29309.1 - 0.42 10.5 3.5 6 6.7 0.1 3.0 3 0 0 3 3 3 0 NTPase NACHT PF05729.12 KDO29309.1 - 0.47 10.4 5.9 4.9 7.0 0.2 2.4 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 KDO29309.1 - 0.53 10.3 7.1 0.96 9.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KDO29309.1 - 0.74 10.0 2.5 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KDO29309.1 - 1.4 8.4 4.7 3.1 7.4 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain OST3_OST6 PF04756.13 KDO29310.1 - 3.1e-21 76.0 1.2 4.7e-21 75.4 1.2 1.4 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family CAP_GLY PF01302.25 KDO29311.1 - 7e-24 83.6 0.9 1.1e-23 82.9 0.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.8 KDO29311.1 - 1.4e-22 80.4 0.0 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Glycos_transf_1 PF00534.20 KDO29312.1 - 4.7e-20 71.8 0.0 9e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO29312.1 - 3.1e-15 56.8 0.2 1.1e-14 55.0 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO29312.1 - 1e-05 25.8 0.0 3.7e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thioredoxin PF00085.20 KDO29314.1 - 1.1e-11 44.7 0.1 1.3e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Ham1p_like PF01725.16 KDO29315.1 - 4.2e-51 173.5 0.0 4.8e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family zf-C2H2_aberr PF17017.5 KDO29316.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Aberrant zinc-finger Myb_DNA-binding PF00249.31 KDO29317.1 - 1.9e-08 34.4 0.1 3e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_A21 PF03566.13 KDO29317.1 - 1 7.5 2.9 1.4 7.1 2.9 1.2 1 0 0 1 1 1 0 Peptidase family A21 Peptidase_M13_N PF05649.13 KDO29318.1 - 3.5e-77 260.7 0.0 4.4e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KDO29318.1 - 1.4e-61 207.7 0.0 2e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 KDO29318.1 - 0.11 12.2 0.3 0.44 10.3 0.3 2.0 2 0 0 2 2 2 0 Peptidase family M48 Methyltransf_25 PF13649.6 KDO29319.1 - 1.6e-08 35.1 0.1 2.8e-08 34.3 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 KDO29319.1 - 2.8e-07 30.1 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KDO29319.1 - 1.9e-06 27.5 0.0 2.3e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 KDO29319.1 - 5.8e-06 26.0 0.0 2.6e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KDO29319.1 - 8.3e-06 25.7 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO29319.1 - 5.1e-05 23.8 0.0 7.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KDO29319.1 - 8.6e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 KDO29319.1 - 0.00015 21.7 0.1 0.00022 21.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO29319.1 - 0.00052 20.7 0.0 0.00096 19.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain RrnaAD PF00398.20 KDO29319.1 - 0.00086 18.5 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 KDO29319.1 - 0.0011 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 KDO29319.1 - 0.0017 18.3 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KDO29319.1 - 0.003 17.5 0.0 0.0037 17.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KDO29319.1 - 0.0036 16.9 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KDO29319.1 - 0.0065 16.0 0.1 0.0088 15.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KDO29319.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KDO29319.1 - 0.07 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_8 PF05148.15 KDO29319.1 - 0.097 12.5 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_9 PF08003.11 KDO29319.1 - 0.18 10.7 0.0 0.34 9.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 KDO29319.1 - 0.21 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.18 KDO29319.1 - 0.24 11.1 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 DNA methylase PPR PF01535.20 KDO29320.1 - 0.0091 16.2 0.2 4.6 7.7 0.0 3.4 3 0 0 3 3 3 1 PPR repeat SRP_TPR_like PF17004.5 KDO29320.1 - 0.083 12.9 0.1 3.7 7.6 0.1 2.6 2 1 0 2 2 2 0 Putative TPR-like repeat tRNA_int_endo PF01974.17 KDO29320.1 - 0.083 13.0 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain TPR_2 PF07719.17 KDO29320.1 - 0.54 10.5 4.5 6.6 7.1 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Tim10_DDP PF02953.15 KDO29321.1 - 1.7e-13 50.0 0.1 2.2e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger C2 PF00168.30 KDO29322.1 - 0.0096 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 KDO29323.1 - 2.9e-07 30.7 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain GFO_IDH_MocA PF01408.22 KDO29325.1 - 4.7e-23 82.3 0.1 1.3e-22 80.9 0.0 1.8 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KDO29325.1 - 0.00079 20.1 0.0 0.0013 19.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 KDO29325.1 - 0.06 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain zf-C3HC4_4 PF15227.6 KDO29328.1 - 1.8e-07 31.2 12.7 7.3e-07 29.2 12.8 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO29328.1 - 3.4e-05 23.8 8.2 3.4e-05 23.8 8.2 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO29328.1 - 0.0024 17.7 18.5 0.0046 16.8 18.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO29328.1 - 0.0031 17.3 13.0 0.0031 17.3 13.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO29328.1 - 0.0086 15.9 18.4 0.0087 15.9 16.0 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO29328.1 - 0.1 12.6 14.7 0.28 11.2 14.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF4196 PF13846.6 KDO29328.1 - 2.3 8.5 24.0 0.067 13.4 16.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Prok-RING_4 PF14447.6 KDO29328.1 - 4.5 7.2 20.0 8.9 6.3 20.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Complex1_LYR PF05347.15 KDO29329.1 - 7.3e-14 51.6 0.9 9.9e-14 51.1 0.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO29329.1 - 9.7e-06 26.2 0.7 1.2e-05 26.0 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like zf-ribbon_3 PF13248.6 KDO29329.1 - 3.3e-05 23.1 3.1 3.3e-05 23.1 3.1 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Complex1_LYR_1 PF13232.6 KDO29329.1 - 0.005 17.4 0.3 0.0087 16.6 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like DZR PF12773.7 KDO29329.1 - 0.0086 16.1 9.9 0.013 15.5 9.9 1.6 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KDO29329.1 - 0.015 16.0 3.3 0.021 15.6 3.3 1.5 1 1 0 1 1 1 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KDO29329.1 - 0.034 13.9 5.2 0.13 12.0 5.2 2.0 1 1 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KDO29329.1 - 0.037 14.2 1.5 0.1 12.8 1.5 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PLATZ PF04640.14 KDO29329.1 - 0.053 14.1 2.2 0.066 13.8 2.0 1.5 1 1 0 1 1 1 0 PLATZ transcription factor Cwf_Cwc_15 PF04889.12 KDO29329.1 - 0.063 13.0 0.2 0.071 12.8 0.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HypA PF01155.19 KDO29329.1 - 0.13 12.3 1.5 0.12 12.4 0.7 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cript PF10235.9 KDO29329.1 - 0.32 11.6 4.7 0.17 12.4 2.6 1.8 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zf-NADH-PPase PF09297.11 KDO29329.1 - 0.75 9.5 9.3 1.9 8.2 0.3 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain TF_Zn_Ribbon PF08271.12 KDO29329.1 - 1.2 8.7 3.8 3.9 7.1 3.8 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding DUF35_N PF12172.8 KDO29329.1 - 2.4 8.1 7.0 0.65 9.9 3.6 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C3HC4_4 PF15227.6 KDO29330.1 - 5.1e-06 26.5 11.9 5.1e-06 26.5 11.9 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KDO29330.1 - 7.5e-05 22.7 8.7 7.5e-05 22.7 8.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO29330.1 - 7.8e-05 22.5 11.4 0.00026 20.8 11.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO29330.1 - 0.00018 21.3 11.0 0.00018 21.3 11.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO29330.1 - 0.00042 20.6 14.2 0.00042 20.6 14.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KDO29330.1 - 0.056 13.4 14.4 0.17 11.9 14.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain NOA36 PF06524.12 KDO29330.1 - 0.12 11.7 7.4 0.19 11.0 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3245 PF11595.8 KDO29330.1 - 0.13 12.8 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Prok-RING_4 PF14447.6 KDO29330.1 - 0.17 11.7 12.0 0.53 10.2 12.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO29330.1 - 0.87 9.8 11.7 2.2 8.5 11.3 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 DNA_pol_phi PF04931.13 KDO29330.1 - 1.3 7.0 4.2 1.7 6.6 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C3HC4_2 PF13923.6 KDO29330.1 - 1.9 8.4 23.1 0.081 12.8 15.8 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Dynein_C PF18199.1 KDO29331.1 - 1.2e-82 277.6 0.0 1.6e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KDO29331.1 - 8.2e-53 178.6 0.0 1.3e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain He_PIG_assoc PF10632.9 KDO29331.1 - 0.16 11.6 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DHC_N1 PF08385.12 KDO29332.1 - 9.5e-185 615.4 12.8 9.5e-185 615.4 12.8 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KDO29332.1 - 2.3e-143 477.1 0.0 3e-141 470.1 0.0 3.6 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO29332.1 - 1.9e-109 366.4 6.6 3.3e-109 365.6 3.4 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO29332.1 - 3.4e-81 272.4 0.0 2.9e-80 269.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO29332.1 - 2.3e-63 213.3 0.2 8.3e-63 211.5 0.2 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO29332.1 - 2.8e-53 180.1 1.3 8.5e-48 162.3 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 KDO29332.1 - 3.1e-39 135.0 13.9 9.4e-39 133.4 13.9 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KDO29332.1 - 5.9e-18 65.2 0.6 3.8e-17 62.6 0.0 2.8 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KDO29332.1 - 7.2e-17 61.7 2.2 1.7e-07 31.3 0.0 6.7 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KDO29332.1 - 4.4e-15 55.7 0.1 2.6e-14 53.2 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KDO29332.1 - 2.3e-10 40.9 2.6 0.0085 16.4 0.0 5.9 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 KDO29332.1 - 5.8e-08 33.2 1.0 0.49 10.8 0.1 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO29332.1 - 2.3e-07 31.4 7.0 0.076 13.4 0.0 5.9 5 1 1 6 6 5 2 AAA ATPase domain Dynein_heavy PF03028.15 KDO29332.1 - 3.9e-07 30.2 0.0 1.8e-06 28.1 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 KDO29332.1 - 2.2e-05 25.0 0.1 1.6 9.3 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KDO29332.1 - 0.00035 20.8 0.2 17 5.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 KDO29332.1 - 0.0011 19.3 0.6 20 5.4 0.1 5.0 5 0 0 5 5 5 0 AAA domain Sigma54_activat PF00158.26 KDO29332.1 - 0.0019 17.9 0.1 0.84 9.3 0.0 3.6 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KDO29332.1 - 0.0025 18.2 0.2 1.3 9.5 0.0 3.9 3 0 0 3 3 3 1 RNA helicase ABC_tran PF00005.27 KDO29332.1 - 0.0028 18.2 0.1 34 4.9 0.0 4.2 3 0 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 KDO29332.1 - 0.0056 16.4 10.3 0.39 10.4 0.0 4.3 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 KDO29332.1 - 0.0067 15.8 0.3 2 7.7 0.1 3.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KDO29332.1 - 0.0077 16.6 6.9 2 8.7 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_24 PF13479.6 KDO29332.1 - 0.01 15.6 1.9 8.2 6.1 0.0 4.1 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 KDO29332.1 - 0.016 15.2 1.1 5.3 6.9 0.0 3.4 3 0 0 3 3 2 0 RsgA GTPase DUF815 PF05673.13 KDO29332.1 - 0.016 14.3 0.2 12 5.0 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) T2SSE PF00437.20 KDO29332.1 - 0.017 14.2 0.5 0.6 9.1 0.0 3.2 4 0 0 4 4 4 0 Type II/IV secretion system protein Rad17 PF03215.15 KDO29332.1 - 0.051 13.5 0.0 24 4.8 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain DUF3987 PF13148.6 KDO29332.1 - 0.055 12.5 0.7 0.72 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TsaE PF02367.17 KDO29332.1 - 0.56 10.2 2.4 64 3.6 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bacillus_HBL PF05791.11 KDO29332.1 - 4 7.2 13.3 6.2 6.6 0.1 4.8 4 0 0 4 4 3 0 Bacillus haemolytic enterotoxin (HBL) EF-hand_8 PF13833.6 KDO29333.1 - 8.2e-09 35.2 0.0 3e-07 30.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO29333.1 - 1.3e-07 32.0 0.1 7.2e-05 23.2 0.0 2.8 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO29333.1 - 3.2e-07 29.4 0.2 5.2e-05 22.5 0.2 2.9 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KDO29333.1 - 0.00012 21.4 0.2 0.004 16.6 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KDO29333.1 - 0.0045 16.8 0.0 0.48 10.5 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain Toprim_2 PF13155.6 KDO29333.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 Toprim-like DnaJ_C PF01556.18 KDO29334.1 - 1.2e-40 139.0 0.1 1.6e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO29334.1 - 9.9e-29 99.3 3.7 1.8e-28 98.5 3.7 1.4 1 0 0 1 1 1 1 DnaJ domain LprI PF07007.12 KDO29334.1 - 0.046 14.4 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Lysozyme inhibitor LprI RPT PF13446.6 KDO29334.1 - 0.11 12.4 0.1 0.47 10.4 0.0 2.1 2 1 0 2 2 2 0 A repeated domain in UCH-protein DUF2046 PF09755.9 KDO29335.1 - 6.2e-30 104.5 30.1 8.4e-30 104.0 30.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF3828 PF12883.7 KDO29335.1 - 1.5 9.2 7.3 5.8 7.3 0.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3828) TMF_TATA_bd PF12325.8 KDO29336.1 - 1.3e-16 60.9 12.5 1.3e-16 60.9 12.5 7.1 2 1 5 7 7 7 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KDO29336.1 - 1.7e-06 27.9 7.3 1.7e-06 27.9 7.3 8.3 6 2 2 9 9 9 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KDO29336.1 - 8.3e-06 26.2 16.9 8.3e-06 26.2 16.9 5.8 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KDO29336.1 - 0.0083 16.3 4.6 0.0083 16.3 4.6 5.6 2 1 5 7 7 7 1 Fibrinogen alpha/beta chain family DUF3398 PF11878.8 KDO29336.1 - 0.022 15.2 0.8 0.16 12.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Homeodomain PF00046.29 KDO29336.1 - 4.8 7.1 8.3 0.51 10.2 0.8 3.4 3 0 0 3 3 3 0 Homeodomain XPA_C PF05181.12 KDO29337.1 - 3.2e-12 46.2 0.1 5.3e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 XPA protein C-terminus MutL_C PF08676.11 KDO29338.1 - 0.00047 20.0 0.1 0.001 18.9 0.0 1.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain NAP PF00956.18 KDO29339.1 - 2.7e-67 226.8 0.4 4.4e-67 226.1 0.4 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Sporozoite_P67 PF05642.11 KDO29339.1 - 0.042 11.9 4.7 0.038 12.1 3.5 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 KDO29339.1 - 0.091 12.5 7.0 0.25 11.0 7.0 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KDO29339.1 - 0.68 8.2 4.7 1.1 7.5 4.7 1.4 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 KDO29339.1 - 2.6 8.5 23.9 0.066 13.6 14.1 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO29339.1 - 4 6.7 13.0 6.4 6.0 13.0 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KDO29339.1 - 8.9 5.6 10.8 0.41 10.0 5.5 1.6 2 1 0 2 2 2 0 SDA1 UCH PF00443.29 KDO29340.1 - 2.3e-19 69.9 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KDO29340.1 - 1.1e-07 31.6 2.0 1.3e-07 31.4 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UCH_1 PF13423.6 KDO29340.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LRR_6 PF13516.6 KDO29341.1 - 3e-10 39.3 7.0 0.02 14.9 0.1 4.5 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KDO29341.1 - 0.021 15.3 0.6 17 6.4 0.2 3.3 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO29341.1 - 0.033 14.6 1.5 1.2 9.7 0.3 2.9 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) SelB-wing_1 PF09105.10 KDO29341.1 - 0.11 12.4 1.6 0.33 10.9 1.6 1.8 1 0 0 1 1 1 0 Elongation factor SelB, winged helix LRR_6 PF13516.6 KDO29342.1 - 3.6e-20 70.2 7.9 3.9e-06 26.5 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KDO29342.1 - 3.5e-08 33.6 0.4 0.01 16.3 0.0 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO29342.1 - 0.00012 22.1 0.0 3.6 8.5 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 KDO29342.1 - 0.011 15.5 5.9 0.23 11.2 0.1 4.0 3 1 1 4 4 4 0 Leucine rich repeat Tmp39 PF10271.9 KDO29344.1 - 0.069 12.2 0.5 0.097 11.7 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein 2TM PF13239.6 KDO29344.1 - 0.11 12.8 0.1 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 2TM domain DnaJ PF00226.31 KDO29345.1 - 5.4e-20 71.3 0.3 8.2e-20 70.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Arm PF00514.23 KDO29346.1 - 3.9e-08 33.0 3.5 0.44 10.7 0.2 4.6 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KDO29346.1 - 4.3e-07 29.6 4.4 1 9.8 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KDO29346.1 - 4.6e-07 30.1 6.6 0.0021 18.4 0.2 3.6 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KDO29346.1 - 5.7e-06 26.7 3.1 0.55 10.8 0.4 4.9 5 1 0 5 5 5 2 HEAT-like repeat V-ATPase_H_C PF11698.8 KDO29346.1 - 9.7e-06 25.7 0.8 2 8.6 0.0 4.3 2 2 2 4 4 4 2 V-ATPase subunit H Cnd1 PF12717.7 KDO29346.1 - 0.0039 17.2 4.1 2.9 7.9 0.5 3.4 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 KDO29346.1 - 0.019 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Armadillo-like Adaptin_N PF01602.20 KDO29346.1 - 0.068 11.7 3.1 3.2 6.2 0.1 3.2 2 1 0 3 3 3 0 Adaptin N terminal region Robl_LC7 PF03259.17 KDO29347.1 - 1.5e-20 72.8 0.0 1.6e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KDO29347.1 - 0.00019 21.3 0.0 0.00021 21.1 0.0 1.3 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 CHASE8 PF17152.4 KDO29347.1 - 0.024 14.9 0.0 0.036 14.3 0.0 1.3 1 1 0 1 1 1 0 Periplasmic sensor domain MCM_bind PF09739.9 KDO29348.1 - 4e-84 283.2 0.0 5e-80 269.6 0.0 2.2 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor CSD PF00313.22 KDO29349.1 - 7.7e-15 54.5 0.1 1.3e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf_CCCH_4 PF18345.1 KDO29349.1 - 2.2e-05 24.4 9.5 2.9e-05 24.0 8.0 2.0 2 0 0 2 2 2 1 Zinc finger domain OB_RNB PF08206.11 KDO29349.1 - 4.6e-05 23.0 0.2 0.00014 21.5 0.2 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain zf-CCCH PF00642.24 KDO29349.1 - 6.2e-05 22.8 6.5 0.00015 21.6 6.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO29349.1 - 0.0015 18.3 7.2 0.0032 17.2 7.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Rho_RNA_bind PF07497.12 KDO29349.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain zf-CCCH_3 PF15663.5 KDO29349.1 - 0.22 11.7 3.5 0.15 12.3 1.7 1.6 2 0 0 2 2 2 0 Zinc-finger containing family PIG-U PF06728.13 KDO29350.1 - 8.8e-79 265.3 24.3 1.1e-78 265.0 24.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF3546 PF12066.8 KDO29351.1 - 5.3e-15 55.6 6.7 1.1e-14 54.5 6.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KDO29351.1 - 5.5e-13 49.7 0.0 1.6e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_12 PF18658.1 KDO29351.1 - 0.031 13.9 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KDO29351.1 - 0.039 14.3 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GDH_N PF12466.8 KDO29351.1 - 0.044 14.0 1.8 0.067 13.4 0.2 2.1 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal DUF4187 PF13821.6 KDO29351.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) THRAP3_BCLAF1 PF15440.6 KDO29351.1 - 0.98 8.4 18.1 1.5 7.8 18.1 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family GRP PF07172.11 KDO29351.1 - 3.8 8.3 9.9 11 6.8 9.9 1.7 1 0 0 1 1 1 0 Glycine rich protein family AAA_22 PF13401.6 KDO29352.1 - 9.7e-11 42.1 0.0 3.1e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KDO29352.1 - 4.4e-09 36.9 0.0 1.2e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO29352.1 - 3.5e-07 30.8 0.2 1.4e-06 28.8 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KDO29352.1 - 1.7e-05 24.7 1.1 2.4e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KDO29352.1 - 2.5e-05 23.8 0.0 5.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 KDO29352.1 - 0.00039 20.4 0.0 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.14 KDO29352.1 - 0.0042 16.3 0.1 0.007 15.6 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KDO29352.1 - 0.0052 17.1 0.2 0.029 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 KDO29352.1 - 0.076 13.1 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA lid domain Ank_2 PF12796.7 KDO29353.1 - 1e-31 109.3 3.4 1.2e-08 35.4 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29353.1 - 3.2e-28 94.6 8.0 3.1e-05 24.0 0.0 8.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 KDO29353.1 - 2.3e-26 91.8 6.3 1.1e-10 41.9 0.1 5.7 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29353.1 - 1e-18 67.1 10.6 4.3e-06 26.9 0.1 6.1 2 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO29353.1 - 1.2e-14 53.9 25.7 0.00013 22.2 0.1 7.7 9 0 0 9 9 9 3 Ankyrin repeat AnkUBD PF18418.1 KDO29353.1 - 0.023 14.9 0.0 0.093 12.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain Toxin_12 PF07740.12 KDO29353.1 - 1.3 9.8 5.7 8.7 7.1 0.5 2.7 2 0 0 2 2 2 0 Ion channel inhibitory toxin Ribosomal_L33 PF00471.20 KDO29354.1 - 6.7e-15 55.3 0.0 8.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Reo_P9 PF06043.11 KDO29354.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Reovirus P9-like family DUF202 PF02656.15 KDO29355.1 - 0.014 15.8 1.9 0.018 15.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) L51_S25_CI-B8 PF05047.16 KDO29356.1 - 9e-10 38.3 0.4 1.4e-09 37.7 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PLU-1 PF08429.11 KDO29356.1 - 0.15 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 PLU-1-like protein Peptidase_S28 PF05577.12 KDO29357.1 - 6.5e-70 236.1 0.0 1.3e-69 235.1 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 OGG_N PF07934.12 KDO29358.1 - 1.7e-24 86.2 0.0 2.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KDO29358.1 - 2.5e-19 69.7 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pkinase PF00069.25 KDO29359.1 - 1.5e-78 263.8 0.0 1.7e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29359.1 - 2.8e-36 125.2 0.0 3.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29359.1 - 5.7e-06 25.9 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO29359.1 - 0.00017 21.0 0.6 0.00033 20.1 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29359.1 - 0.0014 18.6 0.0 0.8 9.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF2167 PF09935.9 KDO29360.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Trp_oprn_chp PF09534.10 KDO29360.1 - 0.24 11.2 8.7 0.26 11.1 4.2 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) p450 PF00067.22 KDO29361.1 - 4.4e-60 203.7 0.0 5.4e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 KDO29362.1 - 4.9e-49 167.4 0.5 6.6e-49 166.9 0.5 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KDO29362.1 - 0.0044 16.6 0.0 0.041 13.5 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase enzyme family DUF5471 PF17565.2 KDO29363.1 - 0.019 15.2 0.1 0.019 15.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5471) AT_hook PF02178.19 KDO29365.1 - 0.013 15.3 2.3 0.14 12.1 2.3 3.0 1 0 0 1 1 1 0 AT hook motif Aminotran_5 PF00266.19 KDO29366.1 - 1.3e-17 63.8 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V ORC2 PF04084.14 KDO29367.1 - 1.7e-55 188.3 0.0 2.1e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SNARE_assoc PF09335.11 KDO29368.1 - 6.8e-15 55.6 3.9 3.8e-14 53.2 3.9 2.4 1 0 0 1 1 1 1 SNARE associated Golgi protein LRR_4 PF12799.7 KDO29368.1 - 0.00014 22.2 2.7 0.092 13.2 0.1 3.8 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO29368.1 - 0.00024 20.9 3.5 0.49 10.6 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat DUF1385 PF07136.11 KDO29368.1 - 0.039 13.2 0.7 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) LRR_1 PF00560.33 KDO29368.1 - 0.073 13.7 1.2 3.5 8.5 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 KDO29368.1 - 8 6.3 6.5 74 3.2 1.2 4.2 4 1 0 4 4 4 0 Leucine rich repeat Methyltransf_16 PF10294.9 KDO29369.1 - 4.3e-14 52.6 0.0 5.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO29369.1 - 0.0072 15.9 0.3 0.019 14.5 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KDO29369.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA PF00004.29 KDO29370.1 - 1.1e-54 184.4 0.0 1.5e-43 148.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KDO29370.1 - 1.2e-20 73.6 0.6 1.2e-20 73.6 0.6 2.7 3 0 0 3 3 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 KDO29370.1 - 1.5e-12 48.3 6.5 4.9e-05 23.8 1.8 4.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KDO29370.1 - 1.5e-09 37.5 0.0 5.9e-05 22.8 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 KDO29370.1 - 3.2e-08 33.9 0.4 0.049 13.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KDO29370.1 - 1.9e-07 30.9 0.1 2.8e-05 23.9 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO29370.1 - 5.5e-07 29.7 0.5 0.005 16.8 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KDO29370.1 - 3.7e-06 27.3 0.0 0.039 14.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 KDO29370.1 - 6.2e-06 26.2 0.1 0.084 12.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KDO29370.1 - 1.2e-05 24.7 0.3 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 KDO29370.1 - 1.5e-05 24.3 0.0 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 KDO29370.1 - 2e-05 24.6 2.6 0.1 12.5 0.0 3.7 3 1 0 4 4 3 2 NACHT domain AAA_14 PF13173.6 KDO29370.1 - 2.8e-05 24.1 0.0 0.31 11.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 KDO29370.1 - 3.2e-05 24.5 0.1 0.29 11.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_25 PF13481.6 KDO29370.1 - 6.6e-05 22.6 6.9 0.27 10.8 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_28 PF13521.6 KDO29370.1 - 8.3e-05 22.9 0.1 0.043 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO29370.1 - 9.2e-05 23.0 0.0 0.042 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO29370.1 - 0.00012 22.3 0.0 0.02 15.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KDO29370.1 - 0.00032 20.2 0.9 0.018 14.4 0.1 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 KDO29370.1 - 0.00036 19.9 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain AAA_2 PF07724.14 KDO29370.1 - 0.00041 20.5 0.0 0.002 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) MMR_HSR1 PF01926.23 KDO29370.1 - 0.00085 19.4 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KDO29370.1 - 0.00092 18.8 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KDO29370.1 - 0.0013 18.6 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KDO29370.1 - 0.0023 17.7 0.0 0.049 13.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KDO29370.1 - 0.0034 17.5 0.3 4.1 7.5 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain DAP3 PF10236.9 KDO29370.1 - 0.0048 16.1 0.0 3.4 6.7 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KDO29370.1 - 0.0049 16.6 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KDO29370.1 - 0.0051 16.5 0.0 1.1 8.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 KDO29370.1 - 0.0055 16.5 0.1 0.82 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KDO29370.1 - 0.0077 15.5 0.2 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain RsgA_GTPase PF03193.16 KDO29370.1 - 0.026 14.4 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 KDO29370.1 - 0.047 14.1 0.2 0.27 11.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO29370.1 - 0.064 13.7 0.0 11 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KDO29370.1 - 0.17 11.8 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Caprin-1_dimer PF18293.1 KDO29370.1 - 0.2 12.1 0.0 2.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Caprin-1 dimerization domain BAG PF02179.16 KDO29371.1 - 4.4e-07 30.2 1.8 4.4e-07 30.2 1.8 2.0 1 1 1 2 2 2 1 BAG domain Uso1_p115_C PF04871.13 KDO29371.1 - 0.011 16.1 1.8 0.015 15.7 1.8 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 KDO29371.1 - 0.02 14.5 2.0 0.025 14.2 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF148 PF02520.17 KDO29371.1 - 0.04 14.0 0.9 0.073 13.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 Phage_tail_APC PF16778.5 KDO29371.1 - 0.6 10.0 3.1 7.7 6.5 0.4 2.6 2 1 0 2 2 2 0 Phage tail assembly chaperone protein HisKA PF00512.25 KDO29371.1 - 2.3 8.3 5.9 4.8 7.3 0.5 2.6 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain Sybindin PF04099.12 KDO29372.1 - 3.3e-34 117.9 0.1 3.7e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KDO29372.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region RPEL PF02755.15 KDO29373.1 - 2e-06 27.3 6.9 0.017 14.8 0.2 4.1 4 0 0 4 4 4 2 RPEL repeat LRR_8 PF13855.6 KDO29374.1 - 7.1e-20 70.5 7.1 1.4e-11 44.0 0.7 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO29374.1 - 1.5e-10 41.1 4.2 0.0003 21.1 0.1 4.7 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO29374.1 - 8.5e-06 25.6 3.5 15 6.6 0.2 5.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KDO29374.1 - 0.0015 18.4 2.6 21 5.5 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 KDO29374.1 - 0.045 13.3 0.5 3 7.3 0.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Keratin_B2_2 PF13885.6 KDO29374.1 - 2.2 8.3 11.0 4.8 7.2 11.0 1.5 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Notch PF00066.17 KDO29374.1 - 4.6 7.8 17.1 8.7 6.9 17.1 1.4 1 0 0 1 1 1 0 LNR domain TPR_2 PF07719.17 KDO29375.1 - 7e-13 47.6 0.8 0.00071 19.5 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29375.1 - 1.2e-10 41.8 3.5 4.1e-06 27.3 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO29375.1 - 1.6e-09 37.1 0.0 0.00013 21.6 0.1 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29375.1 - 4.4e-08 32.7 0.0 0.00027 20.9 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29375.1 - 2.6e-07 31.0 3.2 0.097 13.2 0.0 6.0 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29375.1 - 4.6e-07 30.0 3.1 0.00092 19.5 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO29375.1 - 1.6e-06 27.7 0.0 0.0018 17.9 0.0 3.6 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.6 KDO29375.1 - 9.8e-06 26.0 12.9 2.8 9.0 0.1 7.3 4 3 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO29375.1 - 4.6e-05 23.5 0.0 0.22 12.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO29375.1 - 0.00045 20.3 6.4 0.014 15.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29375.1 - 0.027 14.5 0.5 7.2 6.9 0.0 5.0 5 1 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO29375.1 - 0.041 14.1 4.5 7.2 6.9 0.4 5.0 4 2 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 ThiF PF00899.21 KDO29376.1 - 6.8e-16 58.4 0.0 7.8e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family ThiF PF00899.21 KDO29377.1 - 7.4e-18 64.8 0.0 1e-08 34.8 0.0 3.2 1 1 2 3 3 3 3 ThiF family E1_4HB PF16191.5 KDO29377.1 - 0.0027 17.9 0.1 0.0066 16.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle 2-Hacid_dh_C PF02826.19 KDO29377.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4097 PF13349.6 KDO29379.1 - 1.9e-12 47.1 1.9 3.7e-12 46.1 1.9 1.5 1 1 0 1 1 1 1 Putative adhesin Tetraspanin PF00335.20 KDO29379.1 - 0.00047 19.9 10.3 0.00047 19.9 10.3 4.0 2 1 0 3 3 3 1 Tetraspanin family TF_Otx PF03529.13 KDO29379.1 - 0.0063 16.9 1.4 0.027 14.8 1.4 2.1 1 0 0 1 1 1 1 Otx1 transcription factor Peptidase_C2 PF00648.21 KDO29380.1 - 1.4e-08 34.2 0.0 2.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Pkinase_Tyr PF07714.17 KDO29381.1 - 2.4e-52 177.8 0.0 3.3e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO29381.1 - 2.4e-47 161.5 0.0 3.7e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PB1 PF00564.24 KDO29381.1 - 2.1e-13 50.0 0.0 6.7e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 PB1 domain Pkinase_fungal PF17667.1 KDO29381.1 - 1.1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase UQ_con PF00179.26 KDO29381.1 - 0.0033 17.1 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kinase-like PF14531.6 KDO29381.1 - 0.0051 16.2 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO29381.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO29381.1 - 0.048 13.3 0.1 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO29381.1 - 0.14 12.1 0.0 0.59 10.0 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO29381.1 - 0.23 10.4 0.4 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain DUF4200 PF13863.6 KDO29383.1 - 6.4e-35 120.1 22.5 6.4e-35 120.1 22.5 5.0 5 0 0 5 5 5 2 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 KDO29383.1 - 0.84 10.1 8.4 1.2 9.7 0.3 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KDO29383.1 - 1 9.6 6.9 3.4 8.0 2.2 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) p450 PF00067.22 KDO29384.1 - 3.1e-85 286.7 0.0 3.8e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HUN PF08729.10 KDO29386.1 - 3.5e-10 39.7 4.0 7.4e-10 38.7 4.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain C2 PF00168.30 KDO29387.1 - 1.2e-10 41.5 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 KDO29388.1 - 2.1e-25 89.0 0.0 3.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain EMC3_TMCO1 PF01956.16 KDO29388.1 - 0.0019 18.0 7.1 0.0027 17.5 7.1 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Borrelia_P83 PF05262.11 KDO29388.1 - 0.47 8.9 5.2 0.53 8.7 5.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 KDO29388.1 - 0.48 10.4 34.6 0.63 10.0 34.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 KDO29388.1 - 1.2 8.4 14.0 1.7 7.9 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 KDO29388.1 - 2.2 5.3 6.8 2.7 5.0 6.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Med15 PF09606.10 KDO29388.1 - 2.7 6.6 45.9 3.3 6.3 45.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.6 KDO29388.1 - 3 5.6 24.7 3.9 5.3 24.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 KDO29388.1 - 8.8 5.0 8.5 12 4.5 8.5 1.1 1 0 0 1 1 1 0 Presenilin Arm PF00514.23 KDO29389.1 - 1.3e-09 37.8 13.4 0.025 14.6 0.1 8.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KDO29389.1 - 0.00012 22.1 3.0 0.024 14.7 0.8 3.9 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 KDO29389.1 - 0.00093 17.5 4.2 0.0073 14.5 0.2 3.0 2 1 0 3 3 3 1 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 KDO29389.1 - 0.016 15.7 2.4 2.2 8.9 0.2 4.6 3 0 0 3 3 3 0 HEAT-like repeat RICTOR_V PF14668.6 KDO29389.1 - 0.02 15.1 0.6 16 5.8 0.0 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 KDO29389.1 - 0.52 10.7 12.7 2.1 8.8 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat p450 PF00067.22 KDO29390.1 - 4.8e-86 289.3 0.0 5.9e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MTBP_N PF14918.6 KDO29390.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding Myb_DNA-bind_4 PF13837.6 KDO29392.1 - 0.00074 19.8 0.0 0.0028 18.0 0.0 2.0 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain FKBP_N PF01346.18 KDO29392.1 - 7.2 7.7 11.4 1.1 10.2 3.3 2.4 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FAM76 PF16046.5 KDO29392.1 - 8.2 5.7 12.4 10 5.4 12.4 1.2 1 0 0 1 1 1 0 FAM76 protein p450 PF00067.22 KDO29393.1 - 9.8e-78 261.9 0.0 1.2e-77 261.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 KDO29394.1 - 2.9e-68 229.4 70.2 1.3e-39 135.8 25.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO29394.1 - 6.2e-30 104.5 0.0 2.2e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO29394.1 - 4e-07 30.2 2.2 0.03 14.1 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 KDO29394.1 - 3.5e-06 26.7 1.3 3.5e-06 26.7 1.3 3.9 4 0 0 4 4 3 2 Plant PDR ABC transporter associated AAA_29 PF13555.6 KDO29394.1 - 5.1e-06 26.1 4.3 0.018 14.8 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 KDO29394.1 - 5.6e-06 26.2 6.7 0.00066 19.5 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter AAA_16 PF13191.6 KDO29394.1 - 5.6e-06 26.8 0.1 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO29394.1 - 3.6e-05 23.7 4.2 0.014 15.3 0.4 2.3 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KDO29394.1 - 0.0016 17.9 1.0 4.3 6.7 0.0 3.8 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KDO29394.1 - 0.0019 17.8 0.2 0.39 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KDO29394.1 - 0.0021 18.3 0.5 2.9 8.1 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KDO29394.1 - 0.0038 17.8 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KDO29394.1 - 0.012 16.1 1.4 0.47 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO29394.1 - 0.021 14.1 1.6 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KDO29394.1 - 0.024 14.4 1.7 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO29394.1 - 0.028 14.9 1.9 8.7 6.8 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KDO29394.1 - 0.032 14.3 4.2 1.1 9.4 0.2 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KDO29394.1 - 0.037 14.0 0.4 7.1 6.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KDO29394.1 - 0.05 14.0 0.6 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KDO29394.1 - 0.21 11.3 3.4 7.8 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KDO29394.1 - 0.21 11.5 0.8 2 8.3 0.1 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 KDO29394.1 - 0.22 11.4 5.2 4.8 7.1 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KDO29394.1 - 0.3 11.2 0.5 11 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KDO29394.1 - 0.44 10.3 2.8 5.5 6.7 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KDO29394.1 - 0.57 9.7 4.2 1.4 8.5 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KDO29394.1 - 0.66 10.0 7.6 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 KDO29394.1 - 5.1 7.3 5.7 23 5.2 0.6 3.1 3 0 0 3 3 3 0 AAA domain ABC2_membrane_3 PF12698.7 KDO29394.1 - 8.1 5.4 57.0 2.8 7.0 24.7 3.1 2 2 0 2 2 2 0 ABC-2 family transporter protein DEAD_2 PF06733.15 KDO29395.1 - 2.6e-49 167.2 0.6 4.5e-49 166.4 0.6 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KDO29395.1 - 2.7e-41 141.6 0.0 6.2e-41 140.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 KDO29395.1 - 1.1e-38 132.9 0.5 8.1e-33 113.7 0.0 3.1 3 0 0 3 3 3 2 Helical and beta-bridge domain ResIII PF04851.15 KDO29395.1 - 5.3e-06 26.5 0.0 0.00019 21.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO29395.1 - 0.00033 20.5 0.4 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO29395.1 - 0.0098 16.2 0.7 4.6 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain SNF2_N PF00176.23 KDO29395.1 - 0.024 13.4 0.9 0.49 9.0 0.9 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain PhoH PF02562.16 KDO29395.1 - 0.05 13.0 0.2 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KDO29395.1 - 0.27 11.6 1.2 1 9.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain MMADHC PF10229.9 KDO29396.1 - 4.9e-28 98.6 0.0 6.1e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein tRNA_U5-meth_tr PF05958.11 KDO29397.1 - 1.1e-16 60.8 0.0 1.1e-16 60.8 0.0 2.1 3 0 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KDO29397.1 - 3.8e-06 26.8 0.3 8e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO29397.1 - 1.4e-05 24.7 0.1 0.00022 20.8 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KDO29397.1 - 2.3e-05 25.0 0.1 6.9e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KDO29397.1 - 0.0002 20.9 0.1 0.00043 19.8 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KDO29397.1 - 0.00054 19.4 0.3 0.00054 19.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KDO29397.1 - 0.0016 18.4 0.6 0.0055 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO29397.1 - 0.025 14.2 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 KDO29397.1 - 0.04 13.3 0.2 0.089 12.1 0.2 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KDO29397.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 KDO29397.1 - 0.41 10.1 2.5 0.57 9.6 0.1 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa DUF4504 PF14953.6 KDO29398.1 - 7.8e-08 32.0 0.0 3.6e-07 29.8 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4504) LRR_8 PF13855.6 KDO29399.1 - 6.5e-12 45.0 4.3 1.6e-11 43.8 4.3 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KDO29399.1 - 5.8e-09 36.1 11.9 1.8e-06 28.1 3.4 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO29399.1 - 3.6e-05 23.7 4.4 0.26 12.0 0.1 3.8 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 KDO29399.1 - 0.0024 17.8 5.1 0.21 11.7 0.5 3.6 3 0 0 3 3 3 2 Leucine Rich repeat HTH_AsnC-type PF13404.6 KDO29399.1 - 0.014 15.2 1.0 0.22 11.4 0.2 3.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3461 PF11944.8 KDO29399.1 - 0.023 14.8 0.7 0.15 12.2 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) Prp19 PF08606.11 KDO29399.1 - 0.21 11.6 10.5 0.21 11.6 0.2 3.6 3 0 0 3 3 3 0 Prp19/Pso4-like HALZ PF02183.18 KDO29399.1 - 1.8 8.9 6.1 0.24 11.6 1.3 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Arm PF00514.23 KDO29400.1 - 1.7e-07 31.0 52.5 0.0021 18.1 0.1 13.6 18 0 0 18 18 18 4 Armadillo/beta-catenin-like repeat KAP PF05804.12 KDO29400.1 - 4.3e-07 28.5 15.9 0.024 12.8 0.1 5.8 6 0 0 6 6 6 3 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KDO29400.1 - 1.2e-06 28.1 0.2 0.36 10.1 0.0 4.3 3 1 1 4 4 4 2 V-ATPase subunit H HEAT_2 PF13646.6 KDO29400.1 - 0.0023 18.3 17.1 0.12 12.7 0.0 7.8 7 2 2 9 9 9 1 HEAT repeats HEAT_EZ PF13513.6 KDO29400.1 - 0.0064 17.0 18.2 0.13 12.8 0.0 7.5 8 0 0 8 8 8 2 HEAT-like repeat PUL PF08324.11 KDO29400.1 - 0.02 14.1 17.1 0.46 9.7 0.2 4.5 5 0 0 5 5 5 0 PUL domain Arm_2 PF04826.13 KDO29400.1 - 0.19 11.1 6.8 2.7 7.4 0.1 4.2 5 0 0 5 5 5 0 Armadillo-like HEAT PF02985.22 KDO29400.1 - 0.5 10.8 0.0 0.5 10.8 0.0 10.9 16 0 0 16 16 16 0 HEAT repeat DUF908 PF06012.12 KDO29400.1 - 3.1 7.1 8.7 4.2 6.7 0.0 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF908) Arm PF00514.23 KDO29401.1 - 2.4e-20 71.9 33.4 2.9e-05 23.9 0.0 13.7 15 0 0 15 15 15 7 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KDO29401.1 - 4.9e-08 32.6 0.4 0.012 14.9 0.0 4.8 2 2 1 3 3 3 2 V-ATPase subunit H HEAT_2 PF13646.6 KDO29401.1 - 1.6e-07 31.6 12.4 0.011 16.1 0.0 7.7 7 0 0 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 KDO29401.1 - 3.7e-06 27.3 16.9 1.6 9.3 0.0 7.5 6 1 1 7 7 7 2 HEAT-like repeat Arm_2 PF04826.13 KDO29401.1 - 8.6e-06 25.4 16.7 0.34 10.3 0.1 7.8 6 3 2 8 8 8 2 Armadillo-like KAP PF05804.12 KDO29401.1 - 5.4e-05 21.5 14.2 1.1 7.3 0.3 5.5 3 2 1 4 4 4 4 Kinesin-associated protein (KAP) DUF383 PF04063.14 KDO29401.1 - 0.0005 19.8 3.7 0.4 10.3 0.1 4.8 4 1 0 5 5 5 1 Domain of unknown function (DUF383) HEAT PF02985.22 KDO29401.1 - 0.002 18.2 15.5 0.17 12.2 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat PUL PF08324.11 KDO29401.1 - 0.0027 17.0 19.2 0.71 9.1 0.1 5.3 5 0 0 5 5 5 3 PUL domain Adaptin_N PF01602.20 KDO29401.1 - 0.39 9.2 12.8 0.16 10.5 0.0 4.4 3 2 1 4 4 4 0 Adaptin N terminal region RICTOR_N PF14664.6 KDO29401.1 - 0.51 9.3 20.2 0.74 8.7 0.1 5.3 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, N-term DUF4572 PF15139.6 KDO29402.1 - 0.0014 18.6 0.1 0.025 14.5 0.0 2.5 1 1 0 2 2 2 1 Domain of unknown function (DUF4572) Transferase PF02458.15 KDO29403.1 - 9.3e-10 37.7 0.0 1.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family Acetyltransf_1 PF00583.25 KDO29404.1 - 1.3e-10 41.5 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO29404.1 - 1.1e-08 35.3 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO29404.1 - 9.5e-08 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO29404.1 - 1.8e-06 28.7 0.0 2.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO29404.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KDO29404.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Glycos_transf_N PF04413.16 KDO29404.1 - 0.047 13.3 0.0 0.087 12.5 0.0 1.5 1 1 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Acetyltransf_15 PF17013.5 KDO29404.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase TFIIE_alpha PF02002.17 KDO29405.1 - 4.8e-14 52.1 3.6 1.3e-13 50.7 3.6 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KDO29405.1 - 0.0027 17.9 0.2 0.0073 16.6 0.2 1.8 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha CRR7 PF12095.8 KDO29405.1 - 0.0032 17.9 0.5 1.2 9.6 0.1 2.9 3 0 0 3 3 3 2 Protein CHLORORESPIRATORY REDUCTION 7 HypA PF01155.19 KDO29405.1 - 0.11 12.6 0.4 0.27 11.3 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1936 PF09151.10 KDO29405.1 - 3.1 7.8 4.9 0.35 10.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Paf1 PF03985.13 KDO29406.1 - 7.7e-57 193.2 1.7 7.7e-57 193.2 1.7 2.4 2 1 0 2 2 2 1 Paf1 IF-2B PF01008.17 KDO29406.1 - 3 7.0 4.4 0.43 9.8 0.2 1.6 2 0 0 2 2 2 0 Initiation factor 2 subunit family Glucosamine_iso PF01182.20 KDO29407.1 - 3.1e-22 79.6 0.0 4.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SAC3_GANP PF03399.16 KDO29411.1 - 2e-33 116.0 0.0 2.3e-29 102.7 0.0 2.1 2 0 0 2 2 2 2 SAC3/GANP family WD40 PF00400.32 KDO29412.1 - 5.5e-47 156.8 26.2 0.00015 22.4 0.1 12.5 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29412.1 - 1.6e-13 50.7 3.2 0.51 10.7 0.0 8.5 6 3 3 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO29412.1 - 0.00025 20.5 0.2 0.015 14.6 0.0 2.7 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KDO29412.1 - 0.0015 17.5 1.0 1.3 7.9 0.0 5.0 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO29412.1 - 0.035 12.8 2.5 1 7.9 0.0 3.5 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 KDO29412.1 - 0.085 12.8 1.2 1.6 8.7 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat EamA PF00892.20 KDO29413.1 - 5.9e-08 33.0 20.7 1.1e-06 28.9 7.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family His_Phos_2 PF00328.22 KDO29414.1 - 3e-07 30.1 0.0 0.0016 17.8 0.0 2.6 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KDO29415.1 - 3.1e-07 30.1 0.1 3.3e-05 23.4 0.1 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PRP3 PF08572.10 KDO29416.1 - 4e-64 216.4 2.3 8.6e-64 215.3 2.3 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KDO29416.1 - 3.5e-43 147.2 0.0 6.4e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) CPSF73-100_C PF11718.8 KDO29416.1 - 0.39 10.2 1.8 4.7 6.7 0.4 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Elicitin PF00964.17 KDO29417.1 - 0.0019 18.3 2.0 0.014 15.5 0.0 2.5 1 1 0 2 2 2 1 Elicitin Radial_spoke PF04712.12 KDO29418.1 - 5e-07 29.0 0.0 3.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Radial spokehead-like protein Dicer_dimer PF03368.14 KDO29419.1 - 5.7e-20 71.3 0.6 1.3e-19 70.2 0.6 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KDO29419.1 - 7.5e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KDO29419.1 - 9.8e-12 45.2 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO29419.1 - 2.3e-10 40.8 0.0 5.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KDO29419.1 - 0.005 17.1 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KDO29419.1 - 0.073 12.8 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 KDO29419.1 - 0.098 13.0 2.4 0.95 9.8 2.4 2.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KDO29419.1 - 0.19 11.4 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DIOX_N PF14226.6 KDO29421.1 - 1.4e-08 35.5 0.0 3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO29421.1 - 0.00014 22.3 0.0 0.00039 20.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SAP PF02037.27 KDO29422.1 - 4.8e-11 42.2 1.0 9.6e-11 41.2 1.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KDO29422.1 - 0.042 13.6 0.6 0.53 10.1 0.2 2.3 2 0 0 2 2 2 0 HeH/LEM domain PI3_PI4_kinase PF00454.27 KDO29424.1 - 2.2e-29 103.0 0.0 1.3e-26 93.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 KDO29424.1 - 0.0013 19.2 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 KDO29424.1 - 0.0028 17.8 2.6 0.007 16.5 2.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KDO29424.1 - 0.056 13.6 2.8 0.11 12.7 2.8 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger zf-C2H2 PF00096.26 KDO29425.1 - 7.4e-18 63.9 31.2 1.7e-05 25.0 1.0 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO29425.1 - 1.1e-15 56.9 25.2 0.0013 19.4 1.9 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KDO29425.1 - 2.8e-12 46.5 29.5 0.00025 21.3 2.0 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KDO29425.1 - 2.2e-05 24.1 20.3 0.2 11.4 0.3 5.0 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KDO29425.1 - 9.6e-05 22.6 12.3 0.018 15.4 1.6 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 KDO29425.1 - 0.0035 18.0 11.5 0.021 15.5 1.0 2.3 2 0 0 2 2 2 2 TRAF-type zinc finger DUF5579 PF17742.1 KDO29425.1 - 0.28 10.7 2.3 3.5 7.1 0.2 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5579) zf-C2H2_aberr PF17017.5 KDO29425.1 - 0.47 10.6 13.4 0.85 9.7 0.1 3.5 2 2 1 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KDO29425.1 - 1 10.0 7.9 27 5.5 0.1 3.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KDO29425.1 - 5.5 7.1 26.0 0.059 13.4 4.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Pkinase PF00069.25 KDO29426.1 - 5e-55 186.7 0.0 6.2e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29426.1 - 1.3e-23 83.7 0.0 1.6e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KDO29426.1 - 0.17 12.0 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain CysG_dimeriser PF10414.9 KDO29427.1 - 0.43 10.3 4.6 33 4.3 0.1 3.3 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region Cullin_binding PF03556.15 KDO29428.1 - 1.4e-31 109.4 0.7 3.1e-31 108.3 0.7 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KDO29428.1 - 7.7e-08 32.0 0.0 2.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain DUF4203 PF13886.6 KDO29429.1 - 1.1e-39 136.2 31.4 1.5e-39 135.8 31.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4203 PF13886.6 KDO29431.1 - 9.1e-46 156.1 31.1 9.1e-46 156.1 31.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) DUF1668 PF07893.13 KDO29431.1 - 0.23 10.8 0.1 0.32 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) ENTH PF01417.20 KDO29432.1 - 5.9e-10 39.3 0.0 9.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KDO29432.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 ANTH domain ELMO_CED12 PF04727.13 KDO29433.1 - 1.5e-28 100.1 0.0 3.8e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family PH PF00169.29 KDO29433.1 - 6.2e-20 71.7 0.6 1e-16 61.3 0.0 3.1 3 1 0 3 3 3 2 PH domain PH_11 PF15413.6 KDO29433.1 - 7.5e-05 23.1 0.3 0.00064 20.1 0.1 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain TetR_C_14 PF17754.1 KDO29433.1 - 0.086 12.8 0.6 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 MftR C-terminal domain CDC24_OB2 PF17245.2 KDO29434.1 - 2.2e-21 76.8 0.0 4.3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB3 PF17244.2 KDO29434.1 - 2.3e-15 56.9 0.0 5e-14 52.6 0.0 2.5 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB1 PF17246.2 KDO29434.1 - 4.1e-07 30.1 0.0 7.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 RCC1 PF00415.18 KDO29435.1 - 6.9e-72 237.9 18.1 4.5e-14 52.8 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29435.1 - 6e-24 83.3 38.7 1.5e-08 34.2 0.6 8.3 9 1 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KDO29435.1 - 0.24 11.1 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split Tetraspanin PF00335.20 KDO29436.1 - 8.5e-08 32.2 2.7 1.2e-07 31.7 2.7 1.2 1 0 0 1 1 1 1 Tetraspanin family LapA_dom PF06305.11 KDO29436.1 - 1.4 8.8 5.9 5.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RCC1 PF00415.18 KDO29437.1 - 2.9e-51 171.9 15.0 5.1e-12 46.2 0.2 7.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29437.1 - 7.4e-28 95.7 27.3 3.7e-05 23.4 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat eIF3_p135 PF12807.7 KDO29437.1 - 6.3e-07 29.6 0.7 1.4e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 Glyco_hydro_18 PF00704.28 KDO29439.1 - 5.1e-25 88.8 0.2 9.3e-24 84.7 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KDO29440.1 - 7.4e-26 91.6 0.3 5.8e-25 88.7 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PT PF04886.12 KDO29440.1 - 1.6e-10 40.3 29.0 2.5e-06 26.9 28.9 3.1 1 1 0 1 1 1 1 PT repeat Metallophos PF00149.28 KDO29441.1 - 3.3e-06 27.8 0.7 3.3e-05 24.5 0.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase VWA_2 PF13519.6 KDO29442.1 - 3.5e-12 46.9 0.0 5.9e-11 43.0 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KDO29442.1 - 2.1e-10 41.1 0.0 3.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KDO29442.1 - 7.5e-05 21.1 0.1 0.00011 20.5 0.1 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KDO29442.1 - 0.00019 20.8 0.1 0.00033 20.0 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KDO29442.1 - 0.0094 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Pkinase PF00069.25 KDO29443.1 - 6.2e-52 176.6 0.0 8.9e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29443.1 - 1.1e-47 162.5 0.0 1.5e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO29443.1 - 2.9e-06 27.5 9.6 0.0006 20.2 0.3 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29443.1 - 3.5e-06 26.7 6.8 0.0004 20.1 0.5 3.0 1 1 1 2 2 2 2 Leucine rich repeat Pkinase_fungal PF17667.1 KDO29443.1 - 0.0065 15.3 0.0 0.0096 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO29443.1 - 0.019 13.9 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO29443.1 - 0.042 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Flavi_propep PF01570.17 KDO29443.1 - 0.063 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide LRR_1 PF00560.33 KDO29443.1 - 0.064 13.8 0.1 20 6.2 0.0 3.9 3 0 0 3 3 2 0 Leucine Rich Repeat Trp_oprn_chp PF09534.10 KDO29443.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LRR_6 PF13516.6 KDO29443.1 - 0.087 12.9 2.3 36 4.8 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat RCC1 PF00415.18 KDO29444.1 - 4.5e-72 238.5 26.6 2.9e-13 50.2 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29444.1 - 3.4e-31 106.4 29.7 6.3e-09 35.4 0.3 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 KDO29444.1 - 1.1 9.2 5.2 12 6.1 1.6 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Cyt-b5 PF00173.28 KDO29445.1 - 6e-07 29.5 0.0 1.5e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF5582 PF17819.1 KDO29446.1 - 2.7e-05 24.6 0.6 4.8e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5582) EF-hand_14 PF17959.1 KDO29446.1 - 0.0054 17.0 0.1 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KDO29446.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair p450 PF00067.22 KDO29447.1 - 3.5e-59 200.8 0.0 4.3e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_GP20 PF06810.11 KDO29448.1 - 0.085 12.7 4.0 0.14 12.0 4.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Vps5 PF09325.10 KDO29449.1 - 0.0037 16.8 0.4 0.0063 16.1 0.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DUF4609 PF15382.6 KDO29449.1 - 0.057 13.3 0.5 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) DDA1 PF10172.9 KDO29449.1 - 0.1 12.9 0.2 0.64 10.3 0.1 2.2 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase bZIP_1 PF00170.21 KDO29449.1 - 0.12 12.4 2.0 0.28 11.3 2.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor Phi_1 PF04674.12 KDO29449.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Phage_GP20 PF06810.11 KDO29450.1 - 0.27 11.0 2.3 0.51 10.1 2.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 KDO29451.1 - 0.014 15.5 0.8 0.014 15.5 0.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor CitG PF01874.16 KDO29452.1 - 0.00025 20.8 0.5 0.0095 15.6 0.4 2.1 2 0 0 2 2 2 1 ATP:dephospho-CoA triphosphoribosyl transferase bZIP_1 PF00170.21 KDO29452.1 - 0.011 15.8 2.8 0.011 15.8 2.8 2.4 1 1 1 2 2 2 0 bZIP transcription factor TipAS PF07739.13 KDO29452.1 - 0.15 12.6 3.8 9.3 6.8 0.3 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Csm1_N PF18504.1 KDO29452.1 - 7.3 7.0 8.3 0.27 11.6 1.5 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain Vps5 PF09325.10 KDO29453.1 - 0.0009 18.9 2.4 0.0014 18.2 2.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like bZIP_1 PF00170.21 KDO29453.1 - 0.017 15.2 2.6 0.017 15.2 2.6 2.7 3 0 0 3 3 3 0 bZIP transcription factor bZIP_1 PF00170.21 KDO29454.1 - 0.0032 17.5 1.4 0.0032 17.5 1.4 2.3 2 0 0 2 2 2 1 bZIP transcription factor DUF3328 PF11807.8 KDO29454.1 - 0.0042 16.9 0.2 0.0081 16.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PGA2 PF07543.12 KDO29454.1 - 0.32 11.0 6.0 4.9 7.1 0.7 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DHC_N2 PF08393.13 KDO29455.1 - 0.0099 15.0 0.4 0.014 14.6 0.4 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DUF29 PF01724.16 KDO29455.1 - 0.16 12.2 3.3 0.27 11.5 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 NADPH_Ox PF08414.10 KDO29456.1 - 0.076 13.3 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase betaPIX_CC PF16523.5 KDO29457.1 - 0.071 12.9 0.4 0.43 10.4 0.5 2.2 2 0 0 2 2 2 0 betaPIX coiled coil DUF29 PF01724.16 KDO29458.1 - 0.08 13.2 0.4 0.17 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF919 PF06034.11 KDO29459.1 - 0.0045 16.8 0.4 0.008 16.0 0.4 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) LOH1CR12 PF10158.9 KDO29462.1 - 0.067 13.2 0.3 0.21 11.6 0.3 1.8 1 0 0 1 1 1 0 Tumour suppressor protein CSN5_C PF18323.1 KDO29462.1 - 0.19 12.6 1.8 0.54 11.2 1.8 1.7 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain OFeT_1 PF16955.5 KDO29463.1 - 0.21 11.3 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter zf-MYND PF01753.18 KDO29464.1 - 1.8e-08 34.3 11.6 3.7e-08 33.3 11.6 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KDO29464.1 - 0.00097 19.4 9.3 0.0019 18.5 9.3 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding TraY PF05509.11 KDO29464.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 TraY domain Rhodanese_C PF12368.8 KDO29464.1 - 0.072 13.5 5.4 0.12 12.7 5.4 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Thioredoxin PF00085.20 KDO29465.1 - 3.6e-08 33.3 0.0 8.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin COMM_domain PF07258.14 KDO29466.1 - 2.6e-05 24.3 0.0 5.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 COMM domain Peptidase_M1 PF01433.20 KDO29468.1 - 7.5e-49 166.2 0.8 1.1e-48 165.7 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KDO29468.1 - 8.3e-35 119.3 0.1 1.8e-34 118.2 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KDO29468.1 - 1.3e-19 71.2 0.0 2e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2063 PF09836.9 KDO29468.1 - 0.058 13.6 0.4 0.19 12.0 0.4 1.9 1 0 0 1 1 1 0 Putative DNA-binding domain HTH_42 PF06224.12 KDO29468.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain zf-Nse PF11789.8 KDO29469.1 - 0.061 13.1 0.4 1.9 8.4 0.0 2.5 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Gram_pos_anchor PF00746.21 KDO29470.1 - 0.38 10.7 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF2613 PF11021.8 KDO29470.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) Lip_A_acyltrans PF03279.13 KDO29471.1 - 5e-22 78.4 0.0 1e-21 77.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Abhydrolase_1 PF00561.20 KDO29471.1 - 2e-06 27.7 0.1 3.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO29471.1 - 0.00018 20.8 0.1 0.002 17.4 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Syntaxin-18_N PF10496.9 KDO29472.1 - 7.4e-06 26.1 1.4 5.4e-05 23.4 0.2 2.9 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KDO29472.1 - 0.00055 19.9 1.8 0.0009 19.2 0.0 2.3 3 0 0 3 3 3 1 SNARE domain betaPIX_CC PF16523.5 KDO29472.1 - 0.0065 16.3 0.1 0.025 14.4 0.1 2.0 1 0 0 1 1 1 1 betaPIX coiled coil CmlA_N PF18456.1 KDO29472.1 - 0.06 12.7 0.9 0.1 11.9 0.1 1.7 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain Dabb PF07876.12 KDO29472.1 - 0.093 13.4 1.8 2.5 8.8 0.1 2.6 2 1 0 2 2 2 0 Stress responsive A/B Barrel Domain YabA PF06156.13 KDO29472.1 - 0.36 11.5 3.7 0.49 11.0 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Myb_CC_LHEQLE PF14379.6 KDO29472.1 - 0.63 9.8 6.9 2 8.2 1.1 3.4 2 1 1 3 3 3 0 MYB-CC type transfactor, LHEQLE motif NARG2_C PF10505.9 KDO29473.1 - 2.7e-15 56.5 0.0 4.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Prim-Pol PF09250.11 KDO29473.1 - 0.0039 17.6 0.0 0.022 15.1 0.0 2.2 1 1 1 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal eIF-3_zeta PF05091.12 KDO29473.1 - 0.061 12.3 0.1 1.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Guanylate_cyc PF00211.20 KDO29474.1 - 4.2e-09 36.3 0.0 3.2e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HemY_N PF07219.13 KDO29474.1 - 0.1 12.8 0.7 0.67 10.2 0.0 2.5 3 0 0 3 3 3 0 HemY protein N-terminus CDC73_C PF05179.14 KDO29475.1 - 6.2e-38 130.0 0.9 1.2e-37 129.1 0.1 1.9 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KDO29475.1 - 2.5e-12 46.8 0.9 9.3e-08 31.7 0.1 2.4 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal Clenterotox PF03505.14 KDO29475.1 - 0.014 15.0 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Clostridium enterotoxin Peptidase_C13 PF01650.18 KDO29476.1 - 6.8e-102 340.4 0.0 9.2e-102 339.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family RelB PF04221.12 KDO29476.1 - 0.0058 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RelB antitoxin RRM_1 PF00076.22 KDO29478.1 - 3.3e-19 68.5 0.0 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NYN PF01936.18 KDO29478.1 - 9.9e-18 65.0 0.0 1.6e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 NYN domain FYDLN_acid PF09538.10 KDO29478.1 - 4.6 8.0 8.3 20 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) RRM_1 PF00076.22 KDO29479.1 - 1.8e-23 82.1 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO29479.1 - 0.026 14.4 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1866 PF08952.11 KDO29479.1 - 0.1 12.4 0.0 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 KDO29479.1 - 0.18 11.9 0.0 1.7 8.8 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif UreD PF01774.17 KDO29480.1 - 2e-58 197.8 0.1 2.3e-58 197.6 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein cNMP_binding PF00027.29 KDO29481.1 - 1.9e-21 75.9 0.5 9.7e-10 38.4 0.0 4.1 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO29481.1 - 4.4e-06 26.6 25.5 0.0026 17.7 4.3 4.5 4 0 0 4 4 4 2 Ion channel PH PF00169.29 KDO29482.1 - 1.4e-12 48.1 0.0 4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 KDO29482.1 - 3.4e-06 27.1 0.0 6.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO29482.1 - 0.0005 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO29482.1 - 0.036 14.5 0.3 0.25 11.8 0.3 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Spike_rec_bind PF09408.10 KDO29482.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Spike receptor binding domain LRR_6 PF13516.6 KDO29484.1 - 6.8e-07 28.8 17.1 0.003 17.5 0.2 8.3 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 KDO29484.1 - 2.3e-05 24.3 9.0 9.1 7.3 0.1 8.2 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 KDO29484.1 - 4.2e-05 23.8 8.0 2.4 8.7 0.0 6.1 7 1 0 7 7 7 3 Leucine Rich repeats (2 copies) Tub PF01167.18 KDO29485.1 - 2.6e-29 102.7 0.3 1.1e-28 100.6 0.3 1.8 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.8 KDO29485.1 - 0.0057 16.3 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) Tub PF01167.18 KDO29486.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Tub family IQ PF00612.27 KDO29487.1 - 0.00038 20.0 15.7 0.03 14.1 2.9 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif PRiA4_ORF3 PF07929.11 KDO29487.1 - 0.53 10.0 2.7 0.47 10.1 1.4 1.5 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein Ank_2 PF12796.7 KDO29488.1 - 0.04 14.5 0.2 0.063 13.9 0.2 1.4 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Thioredoxin PF00085.20 KDO29489.1 - 9.6e-42 141.2 0.1 2.1e-30 104.8 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KDO29489.1 - 6.3e-07 29.8 0.1 0.0024 18.3 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KDO29489.1 - 2.9e-05 24.1 0.0 0.038 13.9 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KDO29489.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 KDO29489.1 - 0.016 15.5 0.0 1.1 9.7 0.0 3.0 2 1 1 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 KDO29489.1 - 0.018 14.4 0.0 0.38 10.1 0.0 2.6 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KDO29489.1 - 0.089 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KDO29489.1 - 0.17 12.1 0.0 0.68 10.2 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Myb_DNA-bind_4 PF13837.6 KDO29490.1 - 0.0017 18.7 0.0 0.0043 17.4 0.0 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain HEAT_EZ PF13513.6 KDO29492.1 - 9.3e-16 58.0 31.8 3.1e-07 30.7 0.0 10.9 12 2 2 14 14 13 5 HEAT-like repeat HEAT_2 PF13646.6 KDO29492.1 - 5.6e-15 55.5 15.4 0.0027 18.1 0.0 9.4 6 2 4 11 11 11 3 HEAT repeats HEAT PF02985.22 KDO29492.1 - 3.1e-14 51.8 24.4 3.1e-05 23.9 0.0 13.3 15 0 0 15 15 13 2 HEAT repeat IBN_N PF03810.19 KDO29492.1 - 1.5e-10 40.8 1.2 2.3e-07 30.6 0.2 3.5 2 1 1 3 3 3 2 Importin-beta N-terminal domain UME PF08064.13 KDO29492.1 - 8.9e-07 28.8 3.0 2.1 8.3 0.0 7.0 7 3 3 10 10 10 3 UME (NUC010) domain Tti2 PF10521.9 KDO29492.1 - 5.8e-06 26.0 0.5 0.00018 21.1 0.0 3.5 4 1 1 5 5 5 1 Tti2 family Vac14_Fab1_bd PF12755.7 KDO29492.1 - 1e-05 26.0 0.0 2.9 8.5 0.0 6.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Importin_rep_4 PF18808.1 KDO29492.1 - 2.7e-05 24.4 2.8 0.36 11.1 0.1 4.4 4 0 0 4 4 3 2 Importin repeat Adaptin_N PF01602.20 KDO29492.1 - 8.7e-05 21.3 11.2 0.2 10.2 1.8 4.9 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 KDO29492.1 - 0.00039 20.1 5.8 7.6 6.0 0.0 6.3 5 2 2 7 7 7 3 CLASP N terminal Arm PF00514.23 KDO29492.1 - 0.041 13.9 9.1 9.5 6.4 0.1 6.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat LINES_N PF14694.6 KDO29492.1 - 0.072 12.5 4.2 0.22 11.0 0.3 2.3 2 0 0 2 2 2 0 Lines N-terminus AAA_lid_5 PF17865.1 KDO29492.1 - 0.15 12.2 0.2 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Midasin AAA lid domain RTP1_C1 PF10363.9 KDO29492.1 - 0.18 12.0 8.1 34 4.7 0.1 5.9 6 1 1 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 KDO29492.1 - 0.23 11.4 2.2 0.28 11.1 0.5 2.1 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus SPT16 PF08644.11 KDO29493.1 - 9e-56 188.2 0.1 9e-56 188.2 0.1 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KDO29493.1 - 2.9e-42 144.2 1.1 1.9e-41 141.5 0.0 2.8 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KDO29493.1 - 1.8e-21 76.8 0.0 3.7e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KDO29493.1 - 9e-14 51.7 0.8 2.5e-13 50.2 0.8 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Oxysterol_BP PF01237.18 KDO29493.1 - 1.1 8.1 4.4 2 7.1 4.4 1.4 1 0 0 1 1 1 0 Oxysterol-binding protein COMM_domain PF07258.14 KDO29494.1 - 1.2e-12 47.8 0.0 5.3e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 COMM domain NT-C2 PF10358.9 KDO29495.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_2 PF07719.17 KDO29495.1 - 0.58 10.4 8.0 18 5.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat C2-C2_1 PF11618.8 KDO29496.1 - 5.7e-36 123.7 0.0 1.7e-34 118.9 0.0 2.7 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 EF-hand_6 PF13405.6 KDO29496.1 - 1.9e-12 46.0 0.5 0.0051 16.6 0.1 9.6 11 0 0 11 11 11 2 EF-hand domain EF-hand_7 PF13499.6 KDO29496.1 - 6e-12 45.8 0.0 2 9.0 0.1 9.0 9 0 0 9 9 9 2 EF-hand domain pair C2 PF00168.30 KDO29496.1 - 6.7e-08 32.8 0.0 0.0023 18.2 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KDO29496.1 - 2e-07 30.0 0.0 0.0088 15.5 0.0 6.4 8 0 0 8 8 8 1 EF hand EF-hand_5 PF13202.6 KDO29496.1 - 0.012 15.1 0.0 0.08 12.5 0.0 2.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KDO29496.1 - 0.014 15.3 0.1 17 5.4 0.0 4.9 5 0 0 5 5 5 0 EF-hand domain pair TFR_dimer PF04253.15 KDO29496.1 - 0.14 12.2 4.0 0.59 10.2 0.0 3.4 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain Caleosin PF05042.13 KDO29496.1 - 0.29 11.1 1.4 50 3.8 0.0 3.9 4 0 0 4 4 4 0 Caleosin related protein IF4E PF01652.18 KDO29497.1 - 7.7e-55 185.0 0.4 9.3e-55 184.8 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Dyp_perox PF04261.12 KDO29497.1 - 0.027 13.5 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family WD40 PF00400.32 KDO29498.1 - 7.1e-37 124.8 24.6 1.5e-08 35.2 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29498.1 - 3e-17 62.7 2.9 0.0012 19.1 0.1 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO29498.1 - 1.4e-05 24.6 0.0 0.16 11.3 0.0 3.7 2 1 2 4 4 4 2 WD40-like domain Nup160 PF11715.8 KDO29498.1 - 8.3e-05 21.4 0.2 4.8 5.7 0.1 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO29498.1 - 0.00063 18.8 1.2 0.36 9.8 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO29498.1 - 0.001 19.0 0.3 0.25 11.2 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KDO29498.1 - 0.19 10.6 4.6 2.5 7.0 1.4 3.5 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Abhydrolase_1 PF00561.20 KDO29499.1 - 1.3e-21 77.4 0.1 2.3e-21 76.6 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO29499.1 - 1.5e-14 55.1 1.6 1.9e-14 54.8 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KDO29499.1 - 0.00024 21.4 0.1 0.00061 20.1 0.1 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus ESCRT-II PF05871.12 KDO29499.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit Abhydrolase_1 PF00561.20 KDO29500.1 - 9.4e-28 97.5 0.1 1.2e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO29500.1 - 2.5e-16 60.9 1.0 3.3e-16 60.6 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KDO29500.1 - 5.6e-06 26.7 0.7 2.3e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Hydrolase_4 PF12146.8 KDO29500.1 - 0.0021 17.4 0.0 0.0053 16.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KDO29500.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 KDO29500.1 - 0.22 10.2 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 KDO29501.1 - 3.6e-27 95.6 1.1 3.7e-26 92.3 1.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO29501.1 - 2.4e-18 67.6 13.8 2.9e-18 67.3 13.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO29501.1 - 8.1e-07 28.5 0.1 2.6e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 KDO29501.1 - 0.00028 21.2 0.1 0.00064 20.1 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus PWI PF01480.17 KDO29503.1 - 4.4e-26 91.0 0.1 7.5e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 PWI domain DUF3040 PF11239.8 KDO29503.1 - 0.003 17.8 2.7 0.014 15.7 2.7 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Trp_oprn_chp PF09534.10 KDO29503.1 - 0.0052 16.6 4.7 0.016 15.0 4.7 1.8 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2244 PF10003.9 KDO29503.1 - 0.0097 15.6 0.6 3.6 7.2 0.2 2.3 2 0 0 2 2 2 2 Integral membrane protein (DUF2244) EVI2A PF05399.11 KDO29503.1 - 0.044 13.4 0.9 0.086 12.4 0.1 1.8 1 1 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) LAP1C PF05609.12 KDO29503.1 - 0.14 11.2 13.6 0.08 12.0 11.9 1.4 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3742 PF12553.8 KDO29503.1 - 0.18 12.0 0.6 0.38 10.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) IlvC PF01450.19 KDO29504.1 - 2.9e-07 30.9 0.0 3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Glucan_synthase PF02364.15 KDO29505.1 - 8.2e-08 30.9 8.6 8.2e-08 30.9 8.6 1.3 1 1 0 1 1 1 1 1,3-beta-glucan synthase component Fig1 PF12351.8 KDO29505.1 - 0.01 15.7 2.4 0.021 14.8 2.4 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3039 PF11238.8 KDO29506.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) DUF4203 PF13886.6 KDO29506.1 - 1.8 8.2 25.5 3.7 7.2 12.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) PIP5K PF01504.18 KDO29507.1 - 6.7e-63 212.5 0.0 1.1e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FGFR3_TM PF18123.1 KDO29507.1 - 0.077 12.5 2.7 0.35 10.4 2.7 2.2 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain ParD_like PF11903.8 KDO29507.1 - 0.099 12.7 0.2 0.53 10.4 0.1 2.2 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system DUF4386 PF14329.6 KDO29507.1 - 0.31 10.9 9.7 2 8.2 0.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4386) LRR_4 PF12799.7 KDO29508.1 - 1.3e-06 28.6 0.1 12 6.4 0.0 6.7 5 4 3 8 8 8 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KDO29508.1 - 0.05 13.5 0.1 0.2 11.6 0.1 2.1 1 0 0 1 1 1 0 F-box domain SpoVG PF04026.12 KDO29508.1 - 0.18 12.0 0.0 42 4.4 0.0 3.2 3 0 0 3 3 3 0 SpoVG LRR_1 PF00560.33 KDO29508.1 - 7.9 7.5 13.4 2.6e+02 2.8 0.0 7.7 10 1 0 10 10 10 0 Leucine Rich Repeat Ala_racemase_N PF01168.20 KDO29509.1 - 1.3e-24 87.1 0.1 1.5e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.6 KDO29510.1 - 1.3e-39 133.7 51.7 1.8e-10 40.4 6.1 4.5 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KDO29510.1 - 5.7e-23 80.6 28.4 5.9e-07 29.7 2.1 5.9 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO29510.1 - 9.9e-09 34.6 22.8 7.1 7.6 0.1 8.3 7 2 2 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 KDO29510.1 - 1.3e-05 24.7 8.3 0.012 15.1 2.6 3.2 1 1 4 5 5 5 4 Leucine-rich repeat DUF2322 PF10084.9 KDO29510.1 - 0.0021 18.0 0.3 12 6.0 0.0 3.6 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2322) LRR_6 PF13516.6 KDO29510.1 - 4.7 7.5 26.8 19 5.6 0.1 7.4 8 0 0 8 8 8 0 Leucine Rich repeat Peptidase_M16_M PF16187.5 KDO29511.1 - 1.7e-61 208.0 0.0 2.5e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KDO29511.1 - 1.6e-35 122.3 0.1 3.4e-35 121.2 0.1 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO29511.1 - 1.3e-22 80.7 0.0 7e-17 62.0 0.0 3.9 3 1 0 3 3 3 2 Peptidase M16 inactive domain HSF_DNA-bind PF00447.17 KDO29512.1 - 1.6e-21 76.7 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding bZIP_1 PF00170.21 KDO29512.1 - 0.012 15.7 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor MIS13 PF08202.11 KDO29512.1 - 0.029 13.6 0.6 0.037 13.3 0.6 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF3874 PF12990.7 KDO29512.1 - 0.11 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) ZapB PF06005.12 KDO29512.1 - 0.17 12.4 3.8 0.29 11.6 3.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Biotin_lipoyl PF00364.22 KDO29513.1 - 1.1e-14 54.0 5.7 1.6e-14 53.5 5.7 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 KDO29513.1 - 3.8e-06 28.5 0.2 0.042 15.4 0.0 2.6 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial GCV_H PF01597.19 KDO29513.1 - 0.0087 16.0 0.7 0.014 15.3 0.7 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 KDO29513.1 - 0.17 11.8 7.7 0.13 12.1 0.8 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 KDO29513.1 - 0.38 11.5 4.7 7.1 7.4 0.3 2.2 1 1 1 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.13 KDO29513.1 - 0.45 10.2 1.8 1.1 8.9 0.6 2.0 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain PIH1 PF08190.12 KDO29514.1 - 1e-27 96.6 0.1 1.9e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KDO29514.1 - 0.0036 17.7 0.0 0.0099 16.3 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain IPK PF03770.16 KDO29516.1 - 6.6e-51 173.0 0.0 1.3e-50 172.0 0.0 1.5 2 0 0 2 2 2 1 Inositol polyphosphate kinase Glyoxalase PF00903.25 KDO29517.1 - 4.5e-06 26.9 0.0 8.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO29517.1 - 5.3e-05 24.0 0.0 6.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KDO29517.1 - 0.0003 20.7 0.0 0.00045 20.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Autoind_bind PF03472.15 KDO29517.1 - 0.048 13.1 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Autoinducer binding domain TruB_C PF09142.11 KDO29517.1 - 0.075 12.8 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PX PF00787.24 KDO29518.1 - 4.4e-05 23.4 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 PX domain Aminotran_MocR PF12897.7 KDO29518.1 - 0.061 12.1 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase TPR_2 PF07719.17 KDO29519.1 - 3e-15 55.0 12.8 0.001 19.0 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29519.1 - 6.2e-11 42.8 24.5 3.2e-06 27.7 2.3 6.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29519.1 - 1.1e-08 35.1 32.7 0.00043 20.9 0.1 10.0 8 2 4 12 12 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO29519.1 - 5.8e-08 32.2 9.5 0.0045 16.8 0.0 7.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29519.1 - 2.2e-06 27.4 5.0 0.015 15.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29519.1 - 1.3e-05 24.8 10.6 0.45 10.7 0.1 6.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29519.1 - 3.8e-05 23.9 32.1 0.26 11.6 3.8 7.4 4 3 4 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 KDO29519.1 - 4e-05 23.2 8.4 0.062 13.0 0.2 5.5 5 1 1 6 6 6 2 TPR repeat ANAPC3 PF12895.7 KDO29519.1 - 0.00013 22.2 8.3 0.16 12.2 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KDO29519.1 - 0.004 17.3 17.0 1 9.5 0.2 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29519.1 - 0.0052 17.3 27.0 0.47 11.0 0.1 6.6 3 2 1 6 6 6 3 Tetratricopeptide repeat Coatomer_E PF04733.14 KDO29519.1 - 0.0061 16.0 1.7 5.4 6.3 0.0 3.8 3 1 1 4 4 4 1 Coatomer epsilon subunit TPR_21 PF09976.9 KDO29519.1 - 0.05 13.3 5.8 1.5 8.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KDO29519.1 - 0.15 12.7 12.9 30 5.5 0.0 6.9 7 2 1 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO29519.1 - 0.47 10.4 0.0 0.47 10.4 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO29519.1 - 9.5 6.9 17.1 5.4 7.6 0.0 7.1 10 1 0 10 10 8 0 Tetratricopeptide repeat LOR PF04525.12 KDO29521.1 - 2e-10 40.6 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related LOR PF04525.12 KDO29522.1 - 3.3e-07 30.1 0.0 4.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related Opi1 PF08618.10 KDO29523.1 - 0.021 14.1 0.7 0.029 13.7 0.7 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 Limkain-b1 PF11608.8 KDO29523.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 DOPA_dioxygen PF08883.11 KDO29524.1 - 9.5e-29 99.7 0.8 1.5e-28 99.1 0.8 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family zf-CCCH PF00642.24 KDO29525.1 - 1.4e-20 72.7 16.2 4.2e-12 45.7 5.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO29525.1 - 3.4e-13 49.2 16.8 1.9e-07 30.9 5.4 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KDO29525.1 - 1.1e-12 47.4 12.8 4e-07 29.7 2.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KDO29525.1 - 7.3e-05 23.4 9.2 0.011 16.4 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KDO29525.1 - 0.00024 21.4 10.3 0.0042 17.5 1.5 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger PMR5N PF14416.6 KDO29525.1 - 0.61 10.4 2.9 6.7 7.1 0.3 2.5 1 1 1 2 2 2 0 PMR5 N terminal Domain Transp_Tc5_C PF04236.15 KDO29526.1 - 5.6 7.4 6.8 6.2 7.3 0.3 2.7 1 1 2 3 3 3 0 Tc5 transposase C-terminal domain PI3K_1B_p101 PF10486.9 KDO29528.1 - 0.17 9.6 0.0 0.29 8.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4431 PF14485.6 KDO29529.1 - 0.0012 18.5 0.7 1.3 8.9 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4431) DUF348 PF03990.14 KDO29529.1 - 0.055 13.2 1.0 0.055 13.2 1.0 1.8 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain ATG16 PF08614.11 KDO29530.1 - 0.0019 18.5 8.9 0.0029 17.9 8.9 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 KDO29530.1 - 0.048 13.9 0.7 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Muted PF14942.6 KDO29530.1 - 0.11 12.9 5.1 0.16 12.3 5.1 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF359 PF04019.12 KDO29530.1 - 0.11 12.1 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF359) Fez1 PF06818.15 KDO29530.1 - 0.12 12.8 6.4 0.15 12.5 6.4 1.1 1 0 0 1 1 1 0 Fez1 YabA PF06156.13 KDO29530.1 - 0.16 12.6 3.7 3.7 8.3 0.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KDO29530.1 - 0.67 10.0 9.1 0.47 10.5 3.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRR_4 PF12799.7 KDO29532.1 - 9.2e-06 25.9 2.0 0.0029 18.0 0.0 3.2 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29532.1 - 1.2e-05 25.0 2.1 5.2e-05 22.9 0.2 2.7 2 1 1 3 3 3 1 Leucine rich repeat AEP1 PF17049.5 KDO29532.1 - 0.036 13.1 0.2 0.11 11.5 0.2 1.7 1 1 0 1 1 1 0 ATPase expression protein 1 Rootletin PF15035.6 KDO29532.1 - 0.099 12.7 1.0 0.86 9.6 0.3 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion LRR_1 PF00560.33 KDO29532.1 - 0.12 13.0 0.1 51 5.0 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat CBFB_NFYA PF02045.15 KDO29532.1 - 1.3 9.7 2.9 3.1 8.5 0.1 2.7 3 0 0 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B OTU PF02338.19 KDO29533.1 - 5.9e-19 68.8 0.2 1.1e-18 67.9 0.2 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KDO29533.1 - 0.014 14.8 1.5 3.9 6.9 0.6 2.8 2 1 0 2 2 2 0 Peptidase C65 Otubain Apolipoprotein PF01442.18 KDO29533.1 - 0.083 12.8 1.0 0.2 11.5 0.7 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain PUFD PF16553.5 KDO29535.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain SnoaL_2 PF12680.7 KDO29536.1 - 0.048 14.3 1.7 0.19 12.4 0.5 2.3 1 1 1 2 2 2 0 SnoaL-like domain bZIP_1 PF00170.21 KDO29536.1 - 0.15 12.2 3.5 0.29 11.2 3.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor SnoaL_2 PF12680.7 KDO29537.1 - 0.019 15.6 0.0 0.052 14.2 0.0 1.9 1 1 1 2 2 2 0 SnoaL-like domain bZIP_2 PF07716.15 KDO29537.1 - 0.028 14.5 7.3 0.05 13.7 7.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper SnoaL_4 PF13577.6 KDO29537.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 SnoaL-like domain bZIP_1 PF00170.21 KDO29537.1 - 0.26 11.4 4.4 0.51 10.5 4.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor Defensin_5 PF18251.1 KDO29537.1 - 0.27 11.4 0.2 0.27 11.4 0.2 2.0 2 0 0 2 2 2 0 Fungal defensin Copsin bZIP_1 PF00170.21 KDO29538.1 - 0.007 16.4 1.5 0.01 15.9 0.9 1.5 2 0 0 2 2 2 1 bZIP transcription factor Trm112p PF03966.16 KDO29540.1 - 0.0022 18.5 0.3 0.0043 17.6 0.3 1.7 1 1 0 1 1 1 1 Trm112p-like protein ELYS PF13934.6 KDO29541.1 - 4.4e-09 36.6 3.7 4.4e-09 36.6 3.7 1.6 2 0 0 2 2 2 1 Nuclear pore complex assembly zf-RING_2 PF13639.6 KDO29544.1 - 2.2e-10 40.7 16.2 3.5e-10 40.1 16.2 1.3 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 KDO29544.1 - 1e-09 38.4 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 KDO29544.1 - 8.9e-07 29.1 12.5 1.8e-06 28.1 12.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO29544.1 - 2.3e-06 27.3 10.9 5.2e-06 26.2 10.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO29544.1 - 2.6e-05 24.2 7.4 4.6e-05 23.4 7.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO29544.1 - 4.8e-05 23.2 11.8 8.5e-05 22.3 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO29544.1 - 0.00018 21.2 11.7 0.00048 19.8 11.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KDO29544.1 - 0.0019 18.2 9.7 0.0047 16.9 9.7 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KDO29544.1 - 0.012 15.6 12.3 0.022 14.7 12.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO29544.1 - 0.013 15.4 13.4 0.027 14.3 13.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO29544.1 - 0.053 13.4 10.0 0.13 12.2 10.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KDO29544.1 - 0.67 9.8 7.2 1.2 9.0 7.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KDO29544.1 - 1.1 9.5 13.6 2.6 8.3 13.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KDO29544.1 - 2.3 7.9 13.0 5.2 6.8 13.0 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 KDO29545.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29545.1 - 7.5e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABM PF03992.16 KDO29546.1 - 2.2e-12 46.9 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 KDO29546.1 - 0.0019 17.6 0.1 0.0023 17.4 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF1330 PF07045.11 KDO29546.1 - 0.07 13.5 0.0 0.098 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Mon1 PF03164.14 KDO29547.1 - 6.2e-59 200.1 0.0 8.1e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 BNIP2 PF12496.8 KDO29548.1 - 0.03 14.8 0.1 0.038 14.4 0.1 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PAN_4 PF14295.6 KDO29549.1 - 1.1e-13 50.9 11.3 1.5e-06 28.0 2.2 3.0 2 0 0 2 2 2 2 PAN domain DPBB_1 PF03330.18 KDO29549.1 - 0.00045 20.5 0.4 0.0014 18.8 0.2 2.0 2 0 0 2 2 2 1 Lytic transglycolase PAN_2 PF08276.11 KDO29549.1 - 0.032 14.3 12.9 0.22 11.7 3.0 2.7 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.12 KDO29549.1 - 0.37 10.6 7.4 1.1 9.2 0.7 2.9 2 0 0 2 2 2 0 PAN-like domain Sporozoite_P67 PF05642.11 KDO29549.1 - 1.1 7.3 4.7 1.7 6.7 4.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DPBB_1 PF03330.18 KDO29550.1 - 0.00043 20.5 0.2 0.001 19.3 0.2 1.7 1 0 0 1 1 1 1 Lytic transglycolase PAN_4 PF14295.6 KDO29550.1 - 0.00053 19.8 1.1 0.0022 17.9 1.1 2.1 1 0 0 1 1 1 1 PAN domain LapA_dom PF06305.11 KDO29551.1 - 0.95 9.3 6.2 2.7 7.9 0.9 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4200 PF13863.6 KDO29552.1 - 1.8e-15 57.4 36.8 4.1e-15 56.2 27.3 3.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KDO29552.1 - 0.17 11.9 12.5 0.17 11.9 1.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KDO29552.1 - 0.2 9.5 13.4 0.26 9.1 13.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 KDO29552.1 - 0.2 11.9 2.4 30 5.0 0.3 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 KDO29552.1 - 0.73 10.1 32.8 19 5.4 21.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HEPN_Toprim_N PF18871.1 KDO29552.1 - 0.8 9.6 16.7 0.27 11.2 10.3 2.1 1 1 1 2 2 2 0 HEPN/Toprim N-terminal domain 1 Fib_alpha PF08702.10 KDO29552.1 - 1.5 9.0 23.3 3.6 7.8 6.0 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KDO29552.1 - 2 7.8 29.7 1.9 7.9 12.3 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal OmpH PF03938.14 KDO29552.1 - 2.2 8.6 32.5 0.13 12.6 2.0 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KDO29552.1 - 3.1 7.1 21.1 15 4.8 21.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 KDO29552.1 - 3.6 8.0 27.2 2.5 8.5 5.7 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 KDO29552.1 - 7.9 6.6 18.5 3.1 7.9 7.4 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SET PF00856.28 KDO29553.1 - 2.9e-13 50.6 0.2 5.8e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 SET domain TMEM144 PF07857.12 KDO29554.1 - 7e-63 212.6 2.2 1.5e-62 211.5 2.2 1.5 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 KDO29554.1 - 2.3e-08 33.7 6.1 8.3e-06 25.3 0.1 2.2 2 0 0 2 2 2 2 Sugar transport protein DMT_YdcZ PF04657.13 KDO29554.1 - 0.014 15.7 20.7 0.32 11.3 10.6 2.5 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ YhhN PF07947.14 KDO29554.1 - 0.72 9.4 9.4 0.044 13.4 1.0 2.2 2 0 0 2 2 2 0 YhhN family La PF05383.17 KDO29555.1 - 1.8e-17 63.1 0.1 3e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 La domain LicD PF04991.13 KDO29556.1 - 0.0013 18.9 1.8 0.0025 18.0 1.8 1.3 1 0 0 1 1 1 1 LicD family MatE PF01554.18 KDO29557.1 - 8e-44 149.1 24.4 2.6e-27 95.5 10.8 2.9 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KDO29557.1 - 2.9e-06 27.4 7.0 2.9e-06 27.4 7.0 4.0 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KDO29558.1 - 2.1e-46 157.5 24.5 2.1e-27 95.7 10.9 2.8 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO29558.1 - 5.3e-05 23.3 13.0 5.3e-05 23.3 13.0 4.4 3 2 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 KDO29558.1 - 0.00023 19.9 7.4 0.00042 19.1 7.4 1.4 1 0 0 1 1 1 1 Lipid II flippase MurJ IQ PF00612.27 KDO29559.1 - 2.8e-26 88.8 43.7 0.0088 15.8 1.3 10.3 9 0 0 9 9 9 9 IQ calmodulin-binding motif MatE PF01554.18 KDO29560.1 - 1.9e-52 177.1 33.7 5e-28 97.8 11.2 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO29560.1 - 8.1e-06 25.9 14.6 8.1e-06 25.9 14.6 3.6 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain GDPD PF03009.17 KDO29561.1 - 3.2e-15 56.6 0.0 5.4e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Thg1 PF04446.12 KDO29562.1 - 2.7e-50 169.6 0.0 4.2e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KDO29562.1 - 4.5e-37 126.9 0.2 6.5e-37 126.4 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain DUF1912 PF08930.10 KDO29562.1 - 0.45 10.7 1.7 0.68 10.1 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) Ank_2 PF12796.7 KDO29563.1 - 2.1e-15 57.0 8.1 2.3e-06 28.1 1.0 6.4 4 3 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29563.1 - 8.2e-11 42.2 9.1 5.2e-06 26.9 0.3 5.9 7 0 0 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29563.1 - 1.5e-07 31.6 11.6 0.05 13.9 0.0 7.2 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29563.1 - 1.4e-06 28.2 13.8 2.4 9.0 0.0 8.1 10 0 0 10 10 10 3 Ankyrin repeat HlyE PF06109.13 KDO29564.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) Peptidase_C2 PF00648.21 KDO29566.1 - 1.6e-49 168.6 0.2 8.4e-49 166.2 0.2 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 KDO29567.1 - 3.3e-66 223.3 3.2 2.5e-65 220.5 3.2 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease DUF4611 PF15387.6 KDO29567.1 - 0.015 15.5 6.6 0.049 13.9 6.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 KDO29567.1 - 0.059 13.4 1.7 0.11 12.6 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 KDO29567.1 - 0.11 12.1 3.4 0.21 11.3 3.4 1.3 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.10 KDO29567.1 - 0.2 12.0 1.7 0.33 11.3 1.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 KDO29567.1 - 0.22 10.8 8.4 0.34 10.2 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KDO29567.1 - 0.22 11.9 4.7 0.81 10.1 4.7 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 KDO29567.1 - 0.34 8.9 2.7 0.49 8.4 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.8 KDO29567.1 - 0.35 11.1 8.9 0.55 10.4 8.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3245 PF11595.8 KDO29567.1 - 0.38 11.2 5.9 3.7 8.0 7.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Nop53 PF07767.11 KDO29567.1 - 0.63 9.4 6.2 1.1 8.6 6.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 KDO29567.1 - 2.1 7.4 9.9 3.1 6.8 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FYDLN_acid PF09538.10 KDO29567.1 - 2.3 9.0 10.6 4.2 8.1 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PPP4R2 PF09184.11 KDO29567.1 - 2.9 7.4 6.7 4.3 6.8 6.7 1.1 1 0 0 1 1 1 0 PPP4R2 Dicty_REP PF05086.12 KDO29567.1 - 4.6 5.1 6.4 6 4.7 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_phi PF04931.13 KDO29567.1 - 5.9 4.9 11.7 7.7 4.5 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAN_4 PF14295.6 KDO29568.1 - 6.5e-16 58.0 10.5 3.2e-08 33.3 1.2 2.3 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 KDO29568.1 - 1.9e-11 43.8 2.1 2.8e-05 24.0 0.2 2.2 1 1 1 2 2 2 2 PAN domain PAN_2 PF08276.11 KDO29568.1 - 0.083 13.0 1.0 0.083 13.0 1.0 2.3 2 0 0 2 2 2 0 PAN-like domain PDR_assoc PF08370.11 KDO29570.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Plant PDR ABC transporter associated C2 PF00168.30 KDO29571.1 - 1.7e-39 134.3 0.0 1.5e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain 5_3_exonuc_N PF02739.16 KDO29571.1 - 0.037 13.9 0.5 0.43 10.5 0.1 2.5 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF1192 PF06698.11 KDO29571.1 - 1.3 9.1 12.6 1.9 8.6 1.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Atg14 PF10186.9 KDO29571.1 - 3.3 6.7 9.4 5.7 5.9 9.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MORN PF02493.20 KDO29572.1 - 3.9e-11 42.2 33.0 0.0042 16.9 0.2 9.6 10 0 0 10 10 10 6 MORN repeat PseudoU_synth_1 PF01416.20 KDO29573.1 - 2.5e-27 95.5 0.0 2e-24 86.2 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase HutD PF05962.11 KDO29574.1 - 1.4e-37 129.4 0.1 1.8e-37 129.1 0.1 1.0 1 0 0 1 1 1 1 HutD GYF_2 PF14237.6 KDO29574.1 - 0.066 13.0 0.6 14 5.6 0.0 3.0 3 0 0 3 3 3 0 GYF domain 2 PP2C PF00481.21 KDO29575.1 - 3.7e-53 180.8 0.0 5e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO29575.1 - 0.00064 19.4 0.1 0.00099 18.8 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C RCC1 PF00415.18 KDO29576.1 - 7.3e-74 244.2 6.7 1.3e-12 48.1 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29576.1 - 6.6e-34 115.0 24.8 5.8e-08 32.3 0.6 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KDO29576.1 - 1.3e-06 28.2 15.6 4.2e-06 26.6 15.6 2.0 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KDO29576.1 - 0.11 12.5 10.7 0.25 11.3 10.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4213 PF13938.6 KDO29576.1 - 0.16 12.2 0.4 0.94 9.8 0.2 2.3 2 1 0 2 2 2 0 Putative heavy-metal chelation Zf_RING PF16744.5 KDO29576.1 - 5.6 7.1 7.7 11 6.2 7.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger DnaJ_C PF01556.18 KDO29577.1 - 3.9e-39 134.1 0.0 5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO29577.1 - 5.1e-24 84.2 1.3 8.4e-24 83.5 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KDO29577.1 - 2.7e-12 46.8 13.9 6.1e-12 45.7 13.9 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KDO29577.1 - 0.013 15.5 16.6 0.3 11.1 5.5 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KDO29577.1 - 2.6 8.1 9.0 0.51 10.4 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Microvir_J PF04726.13 KDO29577.1 - 2.7 8.1 6.7 0.81 9.7 2.0 2.4 2 0 0 2 2 2 0 Microvirus J protein ABM PF03992.16 KDO29578.1 - 8.5e-13 48.2 0.1 1e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 KDO29578.1 - 0.00052 19.5 0.0 0.00061 19.3 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase DUF1330 PF07045.11 KDO29578.1 - 0.022 15.1 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Dabb PF07876.12 KDO29578.1 - 0.038 14.6 0.0 0.049 14.3 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain PH PF00169.29 KDO29579.1 - 0.2 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 PH domain EF-hand_7 PF13499.6 KDO29580.1 - 3.2e-06 27.5 0.2 0.0091 16.4 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO29580.1 - 0.0018 18.0 0.2 0.23 11.5 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 KDO29580.1 - 0.009 15.5 0.0 0.095 12.3 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KDO29580.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KDO29580.1 - 0.076 12.9 0.1 0.53 10.2 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair U83 PF17465.2 KDO29580.1 - 0.21 11.7 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product GIDE PF12483.8 KDO29583.1 - 0.0061 16.0 0.0 0.051 13.0 0.0 2.4 2 1 0 2 2 2 1 E3 Ubiquitin ligase Peptidase_M14 PF00246.24 KDO29584.1 - 3.7e-18 66.4 0.6 2e-17 63.9 0.6 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase EphA2_TM PF14575.6 KDO29584.1 - 0.052 14.4 0.0 0.12 13.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KDO29584.1 - 1.5 9.4 5.5 39 4.9 0.1 3.8 4 0 0 4 4 4 0 Chitin synthesis regulation, resistance to Congo red Glycos_transf_1 PF00534.20 KDO29586.1 - 1.9e-07 30.8 0.0 2.3e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO29586.1 - 2.8e-07 31.0 0.0 4.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO29586.1 - 0.002 18.5 0.0 0.0037 17.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO29588.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 AD PF09793.9 KDO29590.1 - 1e-22 80.0 0.0 1.5e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 KDO29590.1 - 6.9e-06 25.7 0.0 0.00026 20.6 0.0 2.1 2 0 0 2 2 2 2 Gemin6 protein PIGA PF08288.12 KDO29591.1 - 1.1e-38 131.7 0.3 3e-38 130.3 0.3 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KDO29591.1 - 3e-26 92.4 0.1 5.6e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KDO29591.1 - 4.1e-24 85.0 0.0 7e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO29591.1 - 9.7e-22 77.8 0.0 1.8e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KDO29591.1 - 1e-09 39.1 0.0 1.9e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KDO29591.1 - 0.00012 22.1 0.2 0.00023 21.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KDO29591.1 - 0.00014 22.2 0.0 0.00041 20.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 zf-C2HC5 PF06221.13 KDO29592.1 - 0.0071 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FTHFS PF01268.19 KDO29592.1 - 0.076 11.2 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase PhyH PF05721.13 KDO29593.1 - 0.0071 16.6 0.2 0.012 15.9 0.2 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CBM26 PF16738.5 KDO29593.1 - 0.17 12.2 0.1 0.42 10.9 0.1 1.6 1 0 0 1 1 1 0 Starch-binding module 26 PhyH PF05721.13 KDO29595.1 - 0.0046 17.2 0.4 0.0077 16.5 0.4 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CCDC154 PF15450.6 KDO29596.1 - 0.0036 15.9 0.3 0.0042 15.7 0.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 ATG16 PF08614.11 KDO29596.1 - 0.014 15.6 0.5 0.018 15.3 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KDO29596.1 - 0.026 14.2 0.2 0.044 13.4 0.2 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4763 PF15960.5 KDO29596.1 - 0.034 13.4 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DivIC PF04977.15 KDO29596.1 - 0.13 12.1 0.6 0.29 10.9 0.2 1.6 1 1 0 1 1 1 0 Septum formation initiator E3_UbLigase_RBR PF18091.1 KDO29597.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain YabA PF06156.13 KDO29597.1 - 0.063 13.9 5.8 0.55 10.9 1.0 4.0 3 0 0 3 3 3 0 Initiation control protein YabA Neuropep_like PF15161.6 KDO29597.1 - 0.069 12.8 0.1 0.3 10.8 0.1 2.2 1 0 0 1 1 1 0 Neuropeptide-like Fez1 PF06818.15 KDO29597.1 - 0.29 11.5 38.1 0.43 11.0 7.0 5.1 5 1 0 5 5 5 0 Fez1 Cep57_CLD_2 PF14197.6 KDO29597.1 - 1.7 8.8 12.3 1.2 9.2 2.0 3.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 KDO29597.1 - 1.9 8.3 12.2 0.67 9.8 3.4 3.3 2 0 0 2 2 2 0 Septum formation initiator DUF5082 PF16888.5 KDO29597.1 - 1.9 8.8 10.1 0.32 11.3 0.9 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) Prominin PF05478.11 KDO29597.1 - 3.3 5.6 4.4 8.8 4.1 4.4 1.8 1 0 0 1 1 1 0 Prominin NUDIX PF00293.28 KDO29598.1 - 0.082 13.0 0.1 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 NUDIX domain DUF3145 PF11343.8 KDO29598.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) DUF4042 PF13251.6 KDO29600.1 - 8.7e-15 54.9 12.8 1.6e-14 54.1 7.2 4.0 4 2 1 5 5 5 1 Domain of unknown function (DUF4042) HEAT PF02985.22 KDO29600.1 - 1.2e-07 31.3 22.5 3.2 8.3 0.0 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 KDO29600.1 - 2.8e-07 30.8 5.4 0.032 14.6 0.0 5.8 5 1 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO29600.1 - 0.012 16.2 0.4 15 6.3 0.0 4.3 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KDO29600.1 - 0.027 14.6 0.2 2.3 8.4 0.0 3.9 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KDO29600.1 - 0.038 14.5 13.7 3.1 8.4 0.1 6.7 8 0 0 8 8 8 0 HEAT-like repeat RSB_motif PF16294.5 KDO29601.1 - 1.2e-09 38.4 1.1 2.3e-09 37.4 0.1 2.0 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 KDO29601.1 - 8e-09 35.1 0.8 1.5e-08 34.2 0.8 1.5 1 0 0 1 1 1 1 SAP domain Elicitin PF00964.17 KDO29603.1 - 3.9e-07 30.1 1.5 1e-06 28.8 1.2 1.9 1 1 0 1 1 1 1 Elicitin Alpha_GJ PF03229.13 KDO29604.1 - 0.019 15.5 24.4 0.019 15.5 24.4 2.8 1 1 2 3 3 3 0 Alphavirus glycoprotein J UME PF08064.13 KDO29605.1 - 0.2 11.6 2.8 1.2 9.0 0.2 2.8 3 0 0 3 3 3 0 UME (NUC010) domain Ribosomal_L1 PF00687.21 KDO29606.1 - 1.2e-28 100.3 2.9 1.3e-28 100.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PKD_channel PF08016.12 KDO29607.1 - 0.00096 17.9 6.8 0.0019 17.0 6.8 1.5 1 0 0 1 1 1 1 Polycystin cation channel DUF420 PF04238.12 KDO29607.1 - 0.011 16.0 1.3 0.034 14.4 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF420) DUF4131 PF13567.6 KDO29607.1 - 2.5 7.7 6.1 0.36 10.4 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Ion_trans PF00520.31 KDO29607.1 - 3.7 6.7 18.3 0.67 9.1 11.1 2.8 2 1 0 2 2 2 0 Ion transport protein PKD_channel PF08016.12 KDO29608.1 - 0.0088 14.8 0.7 0.0088 14.8 0.7 3.9 2 1 2 4 4 4 1 Polycystin cation channel BPD_transp_1 PF00528.22 KDO29608.1 - 1.9 8.2 10.5 1.3 8.7 0.5 3.2 3 0 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component Ion_trans PF00520.31 KDO29609.1 - 2.1e-09 37.0 6.5 2.1e-09 37.0 6.5 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO29609.1 - 0.016 13.9 0.9 0.016 13.9 0.9 2.5 2 1 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.31 KDO29610.1 - 1.5e-08 34.1 10.0 1.5e-08 34.1 10.0 1.6 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO29610.1 - 0.28 9.8 11.4 0.1 11.3 0.5 2.9 2 1 1 3 3 3 0 Polycystin cation channel DUF1230 PF06799.11 KDO29612.1 - 0.96 9.6 5.4 0.36 10.9 1.0 2.2 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 PKD_channel PF08016.12 KDO29613.1 - 0.04 12.6 6.5 0.013 14.2 3.2 1.8 2 0 0 2 2 2 0 Polycystin cation channel DUF420 PF04238.12 KDO29613.1 - 0.044 14.1 0.9 0.044 14.1 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF420) H_PPase PF03030.16 KDO29615.1 - 1e-236 787.6 39.5 1.3e-236 787.3 39.5 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Peptidase_M20 PF01546.28 KDO29617.1 - 2.2e-23 83.1 0.7 3e-23 82.6 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO29617.1 - 7.3e-10 38.7 0.1 8.5e-09 35.3 0.3 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain FA_desaturase PF00487.24 KDO29618.1 - 2.7e-14 53.6 19.1 6e-14 52.5 19.1 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DPPIV_N PF00930.21 KDO29619.1 - 6.8e-69 232.3 0.0 5.7e-67 226.0 0.0 2.2 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KDO29619.1 - 2.6e-46 157.8 0.2 3.8e-46 157.2 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KDO29619.1 - 2.6e-10 40.4 3.6 3.5e-09 36.7 1.9 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 KDO29619.1 - 0.00024 21.0 1.0 0.24 11.4 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DLH PF01738.18 KDO29619.1 - 0.071 12.6 0.8 0.76 9.3 0.8 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KDO29619.1 - 0.11 11.8 0.9 0.46 9.7 0.8 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF5043 PF16446.5 KDO29620.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) Methyltransf_7 PF03492.15 KDO29623.1 - 6.6e-41 140.6 0.0 7.8e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_7 PF03492.15 KDO29624.1 - 2.2e-42 145.5 0.0 2.9e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase FYVE PF01363.21 KDO29625.1 - 6.9e-05 22.9 8.5 0.00014 22.0 8.5 1.6 1 1 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO29625.1 - 0.0063 15.9 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 START domain Mannosyl_trans3 PF11051.8 KDO29626.1 - 1.6e-32 113.0 0.0 8.9e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative Ank_2 PF12796.7 KDO29627.1 - 1.5e-18 67.1 2.5 7.1e-10 39.3 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29627.1 - 2.9e-18 66.0 0.9 9.7e-13 48.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KDO29627.1 - 2.9e-13 49.5 10.0 6.4e-13 48.3 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KDO29627.1 - 4.7e-12 45.9 0.6 1.4e-07 31.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29627.1 - 6.9e-10 38.3 0.1 0.00019 21.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KDO29627.1 - 9.4e-07 29.0 1.3 5.5e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat zf-RING_2 PF13639.6 KDO29627.1 - 9.9e-06 25.8 11.2 9.9e-06 25.8 11.2 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KDO29627.1 - 0.0025 17.6 11.0 0.0052 16.6 11.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO29627.1 - 0.0059 16.5 10.6 0.0059 16.5 10.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain PH PF00169.29 KDO29627.1 - 0.0072 16.8 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 PH domain zf-C3HC4_2 PF13923.6 KDO29627.1 - 0.013 15.3 12.7 0.013 15.3 12.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KDO29627.1 - 0.11 12.2 6.6 0.24 11.1 6.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KDO29627.1 - 0.66 9.8 7.5 1.4 8.8 7.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KDO29627.1 - 4.4 7.4 9.2 10 6.3 9.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Annexin PF00191.20 KDO29631.1 - 1.4e-51 172.5 0.0 1.5e-13 50.6 0.0 4.2 4 0 0 4 4 4 4 Annexin NUC173 PF08161.12 KDO29632.1 - 3.2e-48 164.1 0.6 3.2e-48 164.1 0.6 4.5 5 1 0 5 5 5 1 NUC173 domain HEAT PF02985.22 KDO29632.1 - 0.00028 20.9 1.4 0.52 10.7 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat RhoGAP PF00620.27 KDO29632.1 - 0.046 13.5 1.3 7.3 6.4 0.0 3.5 3 0 0 3 3 3 0 RhoGAP domain Nipped-B_C PF12830.7 KDO29632.1 - 0.76 9.7 6.5 1.5 8.7 0.2 4.3 5 2 0 5 5 5 0 Sister chromatid cohesion C-terminus MMS19_N PF14500.6 KDO29633.1 - 7.1e-70 235.6 0.1 3e-69 233.5 0.1 2.2 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KDO29633.1 - 6.1e-28 98.1 3.7 6.1e-28 98.1 3.7 3.1 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 KDO29633.1 - 3.8 8.0 5.7 25 5.5 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat RRF PF01765.19 KDO29634.1 - 6e-47 159.6 4.0 8.2e-47 159.2 1.0 1.9 1 1 1 2 2 2 1 Ribosome recycling factor SBP_bac_3 PF00497.20 KDO29634.1 - 0.025 14.0 0.1 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 REF PF05755.12 KDO29634.1 - 0.064 13.1 0.8 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Ish1 PF10281.9 KDO29634.1 - 0.11 12.8 0.7 0.24 11.7 0.1 1.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Med7 PF05983.11 KDO29634.1 - 0.21 11.7 1.4 7.6 6.6 0.0 2.4 2 1 0 2 2 2 0 MED7 protein DUF883 PF05957.13 KDO29634.1 - 2.2 9.0 5.7 1.5 9.5 2.9 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KDO29634.1 - 2.8 8.5 11.6 0.32 11.6 5.0 2.5 3 1 0 3 3 3 0 YtxH-like protein Ank_2 PF12796.7 KDO29635.1 - 7.2e-15 55.4 9.5 1.6e-06 28.6 0.9 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29635.1 - 1.7e-12 47.6 11.2 0.006 17.1 0.5 5.7 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29635.1 - 3.9e-07 30.2 15.2 0.16 12.3 0.4 6.9 2 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29635.1 - 3.9e-06 26.8 10.5 5.4 7.9 0.0 7.5 8 0 0 8 8 8 2 Ankyrin repeat DUF249 PF03158.13 KDO29635.1 - 0.0038 17.0 0.3 0.75 9.5 0.3 3.1 3 0 0 3 3 3 1 Multigene family 530 protein DUF4821 PF16092.5 KDO29635.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) FYVE PF01363.21 KDO29636.1 - 2.1e-05 24.6 16.5 5.3e-05 23.3 16.5 1.7 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO29636.1 - 0.001 19.3 6.0 0.0024 18.1 6.0 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3074 PF11274.8 KDO29636.1 - 0.0091 16.0 0.0 0.3 11.1 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF3074) FpoO PF10621.9 KDO29636.1 - 0.25 11.7 4.4 0.48 10.8 4.4 1.4 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO TctB PF07331.11 KDO29638.1 - 7.1 6.9 9.4 1 9.6 5.5 1.7 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Tic110 PF16940.5 KDO29641.1 - 3.8 5.9 5.3 5.3 5.4 5.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF5522 PF17653.1 KDO29642.1 - 3e-20 71.9 6.9 5.4e-20 71.1 6.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 KDO29642.1 - 8e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Peripla_BP_2 PF01497.18 KDO29642.1 - 0.00012 21.7 0.1 0.00046 19.8 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein PQQ_3 PF13570.6 KDO29642.1 - 0.11 13.0 0.0 0.54 10.8 0.0 2.2 1 0 0 1 1 1 0 PQQ-like domain FYVE PF01363.21 KDO29643.1 - 8.4e-06 25.8 6.5 1.6e-05 25.0 6.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 KDO29643.1 - 0.0014 18.9 1.9 0.0029 17.9 1.9 1.5 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 KDO29643.1 - 0.19 11.6 2.8 0.45 10.4 2.8 1.6 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.24 KDO29643.1 - 2 8.6 7.8 0.82 9.9 4.5 2.0 2 0 0 2 2 2 0 B-box zinc finger ADIP PF11559.8 KDO29645.1 - 0.00023 21.3 12.4 0.00023 21.3 12.4 5.8 4 2 0 5 5 5 3 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KDO29645.1 - 0.0066 16.5 12.5 0.0066 16.5 12.5 6.4 4 2 1 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KfrA_N PF11740.8 KDO29645.1 - 0.062 14.0 0.3 0.062 14.0 0.3 8.9 1 1 6 8 8 8 0 Plasmid replication region DNA-binding N-term Filament PF00038.21 KDO29645.1 - 0.7 9.4 84.5 0.02 14.5 2.1 4.1 3 1 1 4 4 4 0 Intermediate filament protein WD40 PF00400.32 KDO29646.1 - 2.1e-52 173.9 25.4 2e-08 34.7 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29646.1 - 1.8e-15 57.0 0.1 0.019 15.3 0.0 6.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO29646.1 - 1.7e-06 28.0 0.1 0.079 12.8 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KDO29646.1 - 0.00017 20.7 6.2 0.91 8.4 0.2 4.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO29646.1 - 0.00047 18.9 8.5 0.17 10.5 0.0 4.9 2 1 3 5 5 5 2 Nucleoporin Nup120/160 DUF1759 PF03564.15 KDO29646.1 - 0.067 13.1 2.2 0.16 11.9 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) IR1-M PF12185.8 KDO29646.1 - 0.11 12.5 4.5 0.3 11.1 4.5 1.8 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain EST1 PF10374.9 KDO29646.1 - 0.11 13.2 2.1 0.22 12.2 2.1 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 FlxA PF14282.6 KDO29646.1 - 0.11 12.5 8.1 0.11 12.5 1.5 2.3 1 1 1 2 2 2 0 FlxA-like protein YabA PF06156.13 KDO29646.1 - 1.7 9.4 6.7 4.1 8.1 2.5 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 KDO29646.1 - 2.4 8.3 9.2 0.49 10.6 4.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 KDO29646.1 - 2.8 8.4 9.2 1 9.8 0.8 2.5 2 0 0 2 2 2 0 Cell division protein ZapB FapA PF03961.13 KDO29646.1 - 3.5 6.1 6.7 5.5 5.5 6.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1579 PF07617.11 KDO29647.1 - 0.014 15.4 0.1 0.16 11.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1579) FAM92 PF06730.11 KDO29647.1 - 0.015 14.8 1.7 0.021 14.3 0.1 1.8 2 1 0 3 3 3 0 FAM92 protein IL17_R_N PF15037.6 KDO29647.1 - 0.026 13.5 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region Apolipoprotein PF01442.18 KDO29647.1 - 0.12 12.2 8.4 0.034 14.0 3.4 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain zf-C3HC4_3 PF13920.6 KDO29648.1 - 1.3e-10 40.9 8.3 2.8e-10 39.9 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO29648.1 - 8.2e-07 28.8 13.2 1.9e-06 27.6 13.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO29648.1 - 1.4e-05 25.0 9.8 2.7e-05 24.0 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO29648.1 - 1.8e-05 24.5 7.2 3.9e-05 23.4 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO29648.1 - 6.4e-05 22.7 8.3 0.00016 21.4 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO29648.1 - 0.00011 22.5 9.4 0.00026 21.2 9.4 1.8 1 0 0 1 1 1 1 Ring finger domain UBA PF00627.31 KDO29648.1 - 0.00014 21.7 0.0 0.00042 20.1 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_UBOX PF13445.6 KDO29648.1 - 0.00077 19.4 9.2 0.0021 18.0 9.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger HATPase_c_3 PF13589.6 KDO29648.1 - 0.0044 16.8 0.0 1.3 8.9 0.0 2.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MIEAP PF16026.5 KDO29648.1 - 0.044 14.0 2.2 0.27 11.4 0.1 2.4 2 0 0 2 2 2 0 Mitochondria-eating protein TerY_C PF15616.6 KDO29648.1 - 0.065 13.3 1.9 0.14 12.3 1.9 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.7 KDO29648.1 - 0.44 10.9 4.2 1.1 9.6 4.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KDO29648.1 - 2.1 8.3 5.1 6.6 6.7 5.1 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KDO29648.1 - 5.5 7.2 9.0 14 5.9 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO29648.1 - 5.8 6.8 6.5 14 5.6 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HAT_KAT11 PF08214.11 KDO29649.1 - 2.9e-23 82.7 0.0 2.9e-23 82.7 0.0 1.4 2 0 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 KDO29649.1 - 4.5e-15 55.5 0.0 1.1e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KDO29649.1 - 7.4e-06 25.8 1.2 7.4e-06 25.8 1.2 3.7 4 1 0 4 4 4 1 PHD-finger PHD_2 PF13831.6 KDO29649.1 - 0.011 15.3 1.6 0.011 15.3 1.6 2.5 3 0 0 3 3 3 0 PHD-finger DUF3772 PF12607.8 KDO29649.1 - 0.25 11.1 1.2 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) DUF3402 PF11882.8 KDO29650.1 - 1.6e-39 136.3 4.9 3e-26 92.6 1.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) La PF05383.17 KDO29651.1 - 3.4e-18 65.4 0.0 8e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 KDO29651.1 - 5.9e-13 48.7 0.2 2.4e-09 37.1 0.0 3.5 4 0 0 4 4 4 2 RNA binding motif YaiA PF16362.5 KDO29651.1 - 0.17 12.0 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 YaiA protein Herpes_U30 PF04523.13 KDO29651.1 - 0.17 9.8 0.0 0.24 9.2 0.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 ATG16 PF08614.11 KDO29652.1 - 4.1 7.6 59.0 16 5.7 13.7 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Ribosomal_L22 PF00237.19 KDO29654.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e DUF1430 PF07242.11 KDO29655.1 - 0.12 12.7 0.2 0.12 12.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF3917 PF13055.6 KDO29655.1 - 0.13 12.7 0.4 0.29 11.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) NOA36 PF06524.12 KDO29655.1 - 0.36 10.1 4.6 0.56 9.5 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.7 KDO29655.1 - 0.66 8.0 3.5 0.88 7.6 3.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_pol_phi PF04931.13 KDO29655.1 - 0.79 7.7 9.3 1.4 6.9 9.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 KDO29655.1 - 0.93 9.1 5.5 1.2 8.8 5.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Herpes_DNAp_acc PF04929.12 KDO29655.1 - 1.4 7.8 6.4 1.8 7.5 6.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Inhibitor_I53 PF11714.8 KDO29655.1 - 2.1 8.6 7.9 5.6 7.2 7.9 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin PGA2 PF07543.12 KDO29655.1 - 4.2 7.4 10.0 9.5 6.2 10.0 1.6 1 1 0 1 1 1 0 Protein trafficking PGA2 BLOC1S3 PF15753.5 KDO29655.1 - 7.6 6.6 10.9 11 6.1 10.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Pyr_redox_2 PF07992.14 KDO29656.1 - 1.1e-37 129.9 0.3 1.7e-37 129.2 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO29656.1 - 7e-16 58.5 1.2 1.3e-15 57.5 0.3 2.0 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO29656.1 - 7.5e-14 52.1 5.0 1e-11 45.2 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO29656.1 - 2.7e-12 46.6 1.5 1.5e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KDO29656.1 - 0.00011 21.5 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KDO29656.1 - 0.0017 17.1 0.6 0.046 12.4 0.9 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KDO29656.1 - 0.003 16.8 1.1 0.003 16.8 1.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KDO29656.1 - 0.0035 16.7 0.6 0.0048 16.3 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KDO29656.1 - 0.0058 15.8 0.5 0.0058 15.8 0.5 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KDO29656.1 - 0.016 15.5 1.0 0.016 15.5 1.0 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KDO29656.1 - 0.028 13.5 4.3 0.041 13.0 3.4 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KDO29656.1 - 0.043 14.2 1.3 8.5 6.9 0.2 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KDO29656.1 - 0.044 13.1 2.4 2.8 7.3 0.0 2.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KDO29656.1 - 0.052 13.1 3.1 0.042 13.4 1.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KDO29656.1 - 0.26 10.6 12.7 0.38 10.0 1.2 3.1 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KDO29656.1 - 1.2 9.0 6.7 2.9 7.7 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KDO29657.1 - 2.6e-59 200.8 0.9 3.9e-59 200.3 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO29657.1 - 1.3e-30 105.9 0.8 3.1e-30 104.7 0.6 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO29657.1 - 8.6e-19 67.9 1.4 6.5e-16 58.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO29657.1 - 2.8e-14 53.1 0.5 1.2e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KDO29657.1 - 0.00029 20.1 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KDO29657.1 - 0.00033 19.9 5.6 0.019 14.1 2.9 2.6 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KDO29657.1 - 0.00058 19.0 0.9 0.00058 19.0 0.9 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KDO29657.1 - 0.00062 18.6 0.4 0.018 13.7 0.5 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KDO29657.1 - 0.0013 18.2 1.5 0.0021 17.5 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KDO29657.1 - 0.0028 17.3 2.9 0.003 17.2 0.3 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KDO29657.1 - 0.014 14.8 0.7 4.5 6.6 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KDO29657.1 - 0.015 14.5 1.2 0.035 13.3 1.2 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KDO29657.1 - 0.028 14.8 0.2 6.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KDO29657.1 - 0.03 13.6 6.4 1 8.6 0.5 3.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KDO29657.1 - 0.06 13.6 3.8 0.22 11.8 3.8 2.1 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KDO29657.1 - 0.31 10.9 2.5 17 5.2 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Stk19 PF10494.9 KDO29658.1 - 4.4e-12 46.2 0.0 6.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF1640 PF07798.11 KDO29660.1 - 1.1e-06 28.8 1.9 2.2e-05 24.6 0.3 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) nsp7 PF08716.10 KDO29660.1 - 0.055 14.1 0.0 0.085 13.5 0.0 1.4 1 0 0 1 1 1 0 nsp7 replicase DUF2877 PF11392.8 KDO29660.1 - 0.2 12.4 0.1 0.54 11.0 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2877) TetR_C_33 PF13305.6 KDO29661.1 - 0.029 15.1 0.4 0.13 13.0 0.1 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AI-2E_transport PF01594.16 KDO29662.1 - 9.4e-28 97.3 34.0 2.5e-24 86.0 23.2 3.1 2 1 0 2 2 2 2 AI-2E family transporter YIEGIA PF14045.6 KDO29662.1 - 0.1 11.4 0.4 0.19 10.6 0.4 1.4 1 0 0 1 1 1 0 YIEGIA protein AA_permease PF00324.21 KDO29663.1 - 2.5e-12 46.2 27.3 3.7e-12 45.6 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO29663.1 - 7.5e-10 38.2 34.9 1e-09 37.8 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_1 PF05106.12 KDO29663.1 - 0.15 12.6 7.4 0.15 12.5 0.1 3.4 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) Methyltransf_7 PF03492.15 KDO29664.1 - 2.9e-16 59.6 0.0 7.5e-16 58.3 0.0 1.5 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase RRP36 PF06102.12 KDO29665.1 - 9.6e-39 133.0 26.3 1.2e-38 132.7 26.3 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DOR PF14839.6 KDO29665.1 - 0.79 9.6 11.7 0.78 9.6 10.5 1.7 1 1 0 1 1 1 0 DOR family PP_kinase_C_1 PF17941.1 KDO29665.1 - 1.2 8.7 5.2 11 5.5 1.9 2.8 1 1 1 2 2 2 0 Polyphosphate kinase C-terminal domain 1 zf-C3HC4_3 PF13920.6 KDO29666.1 - 3.5e-11 42.8 13.8 6.3e-11 42.0 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 KDO29666.1 - 5.9e-11 42.8 0.1 1.7e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO29666.1 - 2.6e-10 40.3 0.1 6.6e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29666.1 - 3.4e-10 40.2 0.3 7.5e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29666.1 - 5.8e-08 32.4 0.3 5.7e-05 23.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KDO29666.1 - 1.6e-05 25.1 3.7 0.00016 22.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat zf-RING_2 PF13639.6 KDO29666.1 - 0.0096 16.2 15.8 0.021 15.2 15.8 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO29666.1 - 0.011 15.6 15.5 0.026 14.4 15.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO29666.1 - 0.23 11.4 14.3 0.55 10.2 14.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DUF4203 PF13886.6 KDO29667.1 - 2e-05 24.4 23.9 3e-05 23.8 23.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) zf-C3HC4_3 PF13920.6 KDO29668.1 - 2e-16 59.6 6.2 3.8e-16 58.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KDO29668.1 - 3.7e-14 52.6 1.7 4.9e-07 29.9 0.6 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO29668.1 - 1.8e-13 50.9 0.1 1.4e-07 32.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KDO29668.1 - 2e-11 43.8 1.1 3.8e-06 27.1 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO29668.1 - 6.3e-11 41.5 0.5 0.0002 21.5 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeat Ank_4 PF13637.6 KDO29668.1 - 1.5e-10 41.4 0.4 3.2e-09 37.2 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 KDO29668.1 - 4.2e-09 36.1 6.7 8.9e-09 35.1 6.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO29668.1 - 1e-06 29.0 6.7 1e-06 29.0 6.7 2.1 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO29668.1 - 3e-06 27.0 6.1 8.1e-06 25.6 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 KDO29668.1 - 3.2e-06 27.6 0.0 5.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 PH domain zf-RING_5 PF14634.6 KDO29668.1 - 1.6e-05 24.8 5.6 1.6e-05 24.8 5.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KDO29668.1 - 0.00012 21.9 7.7 0.00012 21.9 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PH_11 PF15413.6 KDO29668.1 - 0.0072 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_UBOX PF13445.6 KDO29668.1 - 0.044 13.8 6.2 0.38 10.8 5.3 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO29668.1 - 0.22 11.7 7.2 0.64 10.2 7.2 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.12 KDO29668.1 - 0.75 9.8 7.6 0.86 9.7 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-P11 PF03854.14 KDO29668.1 - 2.4 7.9 10.5 0.07 12.8 3.6 2.2 2 1 0 2 2 2 0 P-11 zinc finger DUF1249 PF06853.12 KDO29669.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) PPTA PF01239.22 KDO29671.1 - 3.1e-46 153.8 13.5 3.2e-11 42.6 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 KDO29671.1 - 0.18 11.7 3.1 0.35 10.8 0.4 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1549) DUF4219 PF13961.6 KDO29671.1 - 6.5 6.5 12.7 9.7 6.0 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4219) Adaptin_N PF01602.20 KDO29672.1 - 2.1e-131 439.0 4.7 2.8e-131 438.7 4.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KDO29672.1 - 2.2e-20 73.0 0.1 3.8e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KDO29672.1 - 5.4e-12 46.0 3.2 5.9e-05 23.2 0.1 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KDO29672.1 - 5e-05 23.2 0.3 0.24 11.8 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KDO29672.1 - 8.8e-05 22.8 7.2 0.056 13.8 0.3 4.6 4 1 0 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO29672.1 - 0.047 14.3 0.6 1.7 9.3 0.0 3.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region MOR2-PAG1_N PF14222.6 KDO29672.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Cell morphogenesis N-terminal V-ATPase_H_C PF11698.8 KDO29672.1 - 0.17 12.0 0.1 26 5.0 0.0 2.9 1 1 1 2 2 2 0 V-ATPase subunit H 4HBT_2 PF13279.6 KDO29674.1 - 3e-23 82.6 0.0 4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KDO29674.1 - 0.021 14.1 0.0 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 Acyl-ACP thioesterase 4HBT PF03061.22 KDO29674.1 - 0.029 14.7 0.2 0.091 13.1 0.2 1.8 1 1 0 1 1 1 0 Thioesterase superfamily NTP_transferase PF00483.23 KDO29676.1 - 2.9e-27 95.8 0.0 4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KDO29676.1 - 6.4e-08 32.0 9.5 3.2e-07 29.8 0.9 3.9 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KDO29676.1 - 1e-06 29.2 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KDO29676.1 - 0.00013 20.2 0.1 0.00019 19.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KDO29676.1 - 0.0011 18.6 0.6 0.0085 15.8 0.1 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Homeodomain PF00046.29 KDO29677.1 - 6.6e-05 22.7 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Uma2 PF05685.12 KDO29678.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative restriction endonuclease AAA_11 PF13086.6 KDO29679.1 - 3.6e-50 171.2 0.6 3.6e-50 171.2 0.6 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KDO29679.1 - 8.1e-46 156.2 0.0 1.6e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO29679.1 - 1.7e-14 54.0 3.4 3.6e-07 30.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KDO29679.1 - 1.6e-09 38.3 0.0 1.9e-08 34.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KDO29679.1 - 0.0028 17.6 0.2 0.028 14.3 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 KDO29679.1 - 0.0053 17.2 0.1 0.022 15.2 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO29679.1 - 0.034 14.4 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO29679.1 - 0.095 13.1 0.4 4.2 7.8 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF737 PF05300.11 KDO29679.1 - 0.19 12.1 5.8 0.52 10.6 5.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ATP-synt_E PF05680.12 KDO29679.1 - 5.6 7.4 7.1 0.79 10.1 2.5 2.0 2 0 0 2 2 2 0 ATP synthase E chain Myosin_head PF00063.21 KDO29680.1 - 2.6e-236 786.1 1.1 3.4e-236 785.7 1.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Aida_C2 PF14186.6 KDO29680.1 - 1.2e-23 83.3 0.0 2.9e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal adhesion IQ PF00612.27 KDO29680.1 - 1.5e-19 67.9 147.1 0.00047 19.7 0.4 18.7 19 0 0 19 19 19 12 IQ calmodulin-binding motif Ank_2 PF12796.7 KDO29680.1 - 1.3e-16 61.0 3.5 4.1e-07 30.5 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO29680.1 - 2.1e-16 59.8 4.3 1e-10 41.6 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29680.1 - 2.1e-13 50.4 1.9 9e-06 26.2 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO29680.1 - 2.1e-12 46.9 0.2 0.00088 19.6 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KDO29680.1 - 4.2e-11 42.0 4.0 0.005 17.3 0.1 5.1 4 0 0 4 4 4 2 Ankyrin repeat Myosin_N PF02736.19 KDO29680.1 - 8.8e-06 25.5 0.1 1.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain PH PF00169.29 KDO29680.1 - 7.8e-05 23.1 0.0 0.00029 21.3 0.0 2.0 2 0 0 2 2 2 1 PH domain AAA_16 PF13191.6 KDO29680.1 - 0.016 15.6 0.0 0.097 13.0 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain Asp PF00026.23 KDO29682.1 - 1e-50 173.0 0.0 1.3e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO29682.1 - 8.4e-10 39.2 0.0 1.9e-05 25.0 0.1 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO29682.1 - 0.078 12.7 0.0 0.38 10.5 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_C1 PF00112.23 KDO29683.1 - 5.1e-62 209.8 1.1 7.1e-62 209.3 1.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KDO29683.1 - 1.6e-12 47.6 0.2 3.6e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) MU117 PF15474.6 KDO29683.1 - 0.0064 17.3 0.2 0.014 16.2 0.2 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene family Peptidase_C1_2 PF03051.15 KDO29683.1 - 0.031 13.0 0.6 3.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family DAGK_prokar PF01219.19 KDO29683.1 - 0.23 11.3 0.1 0.42 10.5 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase UCH PF00443.29 KDO29694.1 - 6.7e-39 133.9 0.0 9.3e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO29694.1 - 1.5e-06 28.0 0.0 0.036 13.7 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DnaJ PF00226.31 KDO29695.1 - 4.1e-24 84.5 1.7 7.2e-24 83.7 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain MID_pPIWI_RE PF18157.1 KDO29695.1 - 0.071 13.4 0.2 6.3 7.1 0.0 2.2 2 0 0 2 2 2 0 MID domain of pPIWI_RE GHMP_kinases_N PF00288.26 KDO29696.1 - 2.6e-15 56.4 3.2 2.6e-15 56.4 3.2 3.0 2 1 1 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KDO29696.1 - 0.00044 20.6 0.4 0.00044 20.6 0.4 3.1 2 2 1 3 3 3 1 GHMP kinases C terminal FYVE PF01363.21 KDO29697.1 - 3.2e-15 56.0 9.3 9.3e-15 54.5 9.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO29697.1 - 0.016 15.5 10.3 0.016 15.5 10.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger WES_acyltransf PF03007.16 KDO29697.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-RING_2 PF13639.6 KDO29697.1 - 7.1 7.0 14.3 35 4.8 14.5 2.2 1 1 0 1 1 1 0 Ring finger domain TFIIA PF03153.13 KDO29698.1 - 3.6 7.5 13.5 4.4 7.2 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Folate_carrier PF01770.18 KDO29699.1 - 1.7e-70 237.8 17.2 2.4e-70 237.3 17.2 1.2 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KDO29699.1 - 2e-09 36.8 25.0 0.00015 20.8 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM107 PF14995.6 KDO29699.1 - 5.2 7.5 15.1 0.86 10.1 2.1 3.3 2 1 1 3 3 3 0 Transmembrane protein hnRNP_Q_AcD PF18360.1 KDO29700.1 - 1e-26 92.7 0.2 2.6e-11 43.3 0.0 4.4 4 0 0 4 4 4 4 Heterogeneous nuclear ribonucleoprotein Q acidic domain Cadherin_C_2 PF16492.5 KDO29701.1 - 0.00042 21.0 0.5 0.0007 20.3 0.1 1.5 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Trp_oprn_chp PF09534.10 KDO29701.1 - 0.014 15.2 0.3 0.017 14.9 0.3 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PRIMA1 PF16101.5 KDO29701.1 - 0.017 15.2 0.6 0.023 14.8 0.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2165 PF09933.9 KDO29701.1 - 0.025 14.6 0.6 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) PGG PF13962.6 KDO29701.1 - 0.028 14.3 0.7 0.042 13.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function TMEM210 PF15195.6 KDO29701.1 - 0.03 14.8 2.3 0.063 13.7 2.3 1.6 1 0 0 1 1 1 0 TMEM210 family RskA PF10099.9 KDO29701.1 - 0.037 14.3 2.6 0.046 14.0 2.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA GNVR PF13807.6 KDO29701.1 - 0.66 9.9 3.3 0.87 9.6 0.6 2.1 1 1 1 2 2 2 0 G-rich domain on putative tyrosine kinase PT PF04886.12 KDO29702.1 - 9.1e-12 44.3 109.3 0.0034 16.9 11.7 6.6 2 2 4 6 6 6 6 PT repeat DUF4064 PF13273.6 KDO29702.1 - 0.079 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) PT PF04886.12 KDO29703.1 - 0.0044 16.5 12.7 0.0044 16.5 12.7 8.6 3 2 3 6 6 6 4 PT repeat AAA_11 PF13086.6 KDO29704.1 - 1.6e-61 208.4 0.0 1.6e-61 208.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KDO29704.1 - 1.1e-50 172.1 0.0 2.6e-50 170.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Med26 PF08711.11 KDO29704.1 - 5.2e-11 42.4 0.2 1.6e-10 40.8 0.2 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain AAA_30 PF13604.6 KDO29704.1 - 1.7e-10 41.0 0.2 0.00011 22.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KDO29704.1 - 6.7e-09 36.2 0.0 0.0023 18.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain DHHA2 PF02833.14 KDO29705.1 - 0.0014 18.8 0.1 0.0021 18.2 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DUF1640 PF07798.11 KDO29705.1 - 0.0069 16.4 6.2 0.012 15.7 6.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 KDO29705.1 - 0.012 15.8 2.2 2.8 8.3 0.1 2.9 2 2 0 2 2 2 0 Homeobox associated leucine zipper DDE_Tnp_IS240 PF13610.6 KDO29705.1 - 0.015 15.6 0.9 0.018 15.3 0.9 1.2 1 0 0 1 1 1 0 DDE domain DUF4476 PF14771.6 KDO29705.1 - 0.022 15.1 2.9 0.043 14.1 2.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4476) Enkurin PF13864.6 KDO29705.1 - 0.13 12.7 5.8 0.98 9.9 1.7 2.2 1 1 1 2 2 2 0 Calmodulin-binding Atg14 PF10186.9 KDO29705.1 - 3 6.9 6.3 3.8 6.5 6.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1640 PF07798.11 KDO29706.1 - 2.4e-09 37.5 9.6 1.8e-08 34.6 9.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4239 PF14023.6 KDO29706.1 - 0.023 14.4 0.2 0.036 13.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Bac_DNA_binding PF00216.21 KDO29706.1 - 0.025 14.8 1.4 0.62 10.3 0.0 2.7 2 1 1 3 3 3 0 Bacterial DNA-binding protein Mito_carr PF00153.27 KDO29706.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein NADH-UOR_E PF16514.5 KDO29706.1 - 0.16 12.3 1.8 0.4 11.0 1.8 1.7 1 1 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E Ribosomal_L18 PF17135.4 KDO29707.1 - 5.6e-87 290.0 3.0 6.7e-87 289.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KDO29707.1 - 0.04 14.6 0.1 0.091 13.4 0.1 1.7 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SIN1_PH PF16979.5 KDO29708.1 - 1.7e-10 41.2 0.7 3.7e-10 40.0 0.7 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 KDO29708.1 - 5.1e-10 39.6 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RBD PF02196.15 KDO29708.1 - 1.8e-05 24.7 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain HAD PF12710.7 KDO29709.1 - 1.4e-07 32.1 0.1 6.4e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO29709.1 - 0.001 19.4 0.0 0.004 17.5 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KDO29709.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KDO29711.1 - 1.6e-38 132.6 0.0 1.9e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29711.1 - 2.4e-34 118.8 0.0 2.8e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO29711.1 - 0.00015 20.7 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO29711.1 - 0.0084 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29711.1 - 0.085 12.8 0.1 0.34 10.8 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Coprogen_oxidas PF01218.18 KDO29721.1 - 0.06 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase PUA PF01472.20 KDO29721.1 - 0.1 12.6 0.1 84 3.2 0.0 3.4 3 0 0 3 3 3 0 PUA domain RTC4 PF14474.6 KDO29721.1 - 0.31 11.2 4.6 90 3.3 0.0 5.0 2 2 3 5 5 5 0 RTC4-like domain Ank_2 PF12796.7 KDO29722.1 - 3.2e-17 62.9 19.4 5.3e-06 26.9 0.5 4.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29722.1 - 4e-07 29.8 14.1 12 6.8 0.1 8.2 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KDO29722.1 - 9e-06 25.9 15.2 0.21 12.0 0.1 6.0 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29722.1 - 0.00081 19.9 15.4 0.1 13.2 0.3 5.8 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO29722.1 - 0.56 10.8 8.9 20 5.8 0.2 5.5 3 2 1 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 KDO29723.1 - 7.1e-07 29.7 3.7 0.0002 21.9 1.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29723.1 - 3.5e-06 27.4 7.1 0.025 15.2 0.5 4.8 2 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29723.1 - 6.9e-06 26.2 6.3 0.1 12.9 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29723.1 - 0.0077 16.7 7.4 51 4.9 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KDO29724.1 - 1.3e-13 51.3 21.1 0.00074 20.1 0.1 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29724.1 - 3e-07 30.9 14.4 0.023 15.3 0.2 7.2 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29724.1 - 1.8e-06 28.1 12.0 2.5 8.5 0.0 6.9 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29724.1 - 1.9e-05 24.7 14.5 6.8 7.6 0.0 8.4 9 1 1 10 10 10 1 Ankyrin repeat DUF2807 PF10988.8 KDO29725.1 - 4.3e-25 88.6 11.1 2e-12 47.3 0.6 2.2 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain Bactofilin PF04519.13 KDO29725.1 - 0.21 11.9 4.4 1.2 9.5 0.6 2.6 1 1 1 2 2 2 0 Polymer-forming cytoskeletal Pkinase_Tyr PF07714.17 KDO29726.1 - 2.7e-36 125.2 0.0 3.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO29726.1 - 2.3e-35 122.2 0.0 3.2e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO29726.1 - 0.00043 19.7 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29726.1 - 0.0023 17.9 1.4 0.2 11.6 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO29726.1 - 0.0027 16.5 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH_6_hur PF04655.14 KDO29726.1 - 0.029 13.7 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Peptidase_S28 PF05577.12 KDO29727.1 - 2.2e-97 326.6 1.7 2.9e-97 326.2 1.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO29727.1 - 3.5e-05 22.7 0.1 6.2e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KDO29727.1 - 0.00072 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family OPT PF03169.15 KDO29728.1 - 1.1e-57 196.0 28.5 1.5e-47 162.6 24.0 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein PDR_CDR PF06422.12 KDO29728.1 - 0.098 12.6 1.7 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 CDR ABC transporter Thr_synth_N PF14821.6 KDO29729.1 - 3e-29 101.1 0.0 6.3e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KDO29729.1 - 6.1e-20 71.8 0.0 6.7e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DnaJ PF00226.31 KDO29731.1 - 1.7e-17 63.3 1.3 2.7e-17 62.7 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_66 PF13199.6 KDO29731.1 - 0.035 12.7 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 LRR_4 PF12799.7 KDO29732.1 - 3.5e-09 36.8 0.2 0.00063 20.1 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29732.1 - 1.5e-07 31.1 1.5 0.0011 18.7 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KDO29732.1 - 0.01 16.2 4.3 1.2 10.0 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2267 PF10025.9 KDO29732.1 - 0.016 15.5 0.4 0.17 12.1 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) CxC6 PF18721.1 KDO29733.1 - 0.016 15.5 5.1 0.016 15.5 5.1 4.2 1 1 3 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases PAS PF00989.25 KDO29733.1 - 0.07 13.1 0.1 8.5 6.4 0.0 2.3 1 1 1 2 2 2 0 PAS fold Crystall PF00030.19 KDO29736.1 - 4.3e-05 23.6 0.0 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Beta/Gamma crystallin SANTA PF09133.10 KDO29736.1 - 0.049 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 SANTA (SANT Associated) EAV_GP5 PF15981.5 KDO29736.1 - 0.071 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus MAR_sialic_bdg PF10564.9 KDO29737.1 - 0.094 12.8 0.7 0.45 10.6 0.2 2.4 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat SH3_1 PF00018.28 KDO29738.1 - 5.3e-14 51.6 0.1 1.2e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KDO29738.1 - 2.2e-13 49.8 0.1 4.7e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KDO29738.1 - 2.8e-13 49.3 0.1 1.1e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain WD40 PF00400.32 KDO29738.1 - 3.8e-10 40.2 21.8 0.47 11.4 0.0 9.2 9 0 0 9 9 9 4 WD domain, G-beta repeat HELP PF03451.14 KDO29738.1 - 1.3e-05 25.0 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 KDO29738.1 - 2.9e-05 24.3 0.5 0.031 14.6 0.1 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO29738.1 - 0.13 11.2 0.3 2.6 6.9 0.0 2.9 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KDO29738.1 - 0.22 10.8 0.0 0.61 9.4 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain Ras PF00071.22 KDO29739.1 - 1.7e-59 200.0 0.3 2.4e-59 199.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO29739.1 - 1.5e-34 118.7 0.3 2.3e-34 118.2 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO29739.1 - 3e-16 59.4 0.0 3.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO29739.1 - 1.6e-06 27.7 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO29739.1 - 2.2e-06 27.7 0.1 3.6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO29739.1 - 2.7e-06 27.1 0.2 2.1e-05 24.1 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KDO29739.1 - 1.3e-05 25.2 0.4 0.01 15.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KDO29739.1 - 0.0021 18.4 0.1 0.01 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO29739.1 - 0.0022 18.4 0.1 0.0051 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KDO29739.1 - 0.0029 17.4 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KDO29739.1 - 0.0033 17.0 0.1 0.0063 16.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KDO29739.1 - 0.0036 17.5 0.5 0.0074 16.5 0.3 1.6 2 0 0 2 2 1 1 AAA domain SRPRB PF09439.10 KDO29739.1 - 0.0041 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KDO29739.1 - 0.0046 16.4 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein NTPase_1 PF03266.15 KDO29739.1 - 0.0061 16.5 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.14 KDO29739.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KDO29739.1 - 0.02 14.7 0.0 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KDO29739.1 - 0.042 14.4 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DNA_pol_E_B PF04042.16 KDO29739.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_24 PF13479.6 KDO29739.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KDO29739.1 - 0.092 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KDO29739.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KDO29739.1 - 0.11 12.2 0.5 0.47 10.2 0.5 2.1 1 1 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KDO29739.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 KDO29739.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad1 PF02144.16 KDO29740.1 - 1.5e-06 27.5 0.1 3.6e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Nucleoside_tran PF01733.18 KDO29741.1 - 2.6e-18 66.5 7.4 5.1e-15 55.7 0.3 2.2 1 1 1 2 2 2 2 Nucleoside transporter RDV-p3 PF09231.10 KDO29741.1 - 0.083 10.6 0.5 0.11 10.2 0.5 1.0 1 0 0 1 1 1 0 Rice dwarf virus p3 Acyl_transf_3 PF01757.22 KDO29742.1 - 6.7e-28 97.7 20.0 9.3e-28 97.3 20.0 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF1418 PF07214.12 KDO29742.1 - 0.044 13.7 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) zf-RanBP PF00641.18 KDO29743.1 - 0.00015 21.0 25.3 0.016 14.5 8.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KDO29743.1 - 1.8 8.7 13.1 4.5 7.4 13.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon YlbD_coat PF14071.6 KDO29744.1 - 0.012 15.9 3.3 0.012 15.9 3.3 1.8 2 0 0 2 2 2 0 Putative coat protein FPL PF09758.9 KDO29746.1 - 2.9e-44 150.6 7.3 5.3e-44 149.8 7.3 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein TPR_12 PF13424.6 KDO29746.1 - 9.7e-25 86.7 7.7 3.8e-06 27.1 0.4 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO29746.1 - 5.6e-11 41.9 5.7 0.0045 16.8 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO29746.1 - 5.3e-05 22.9 9.1 0.12 12.2 0.2 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29746.1 - 0.00086 19.2 0.7 2.5 8.3 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO29746.1 - 0.0027 17.7 12.0 2.7 8.3 0.3 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29746.1 - 0.023 15.3 6.8 3.1 8.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29746.1 - 1.6 9.1 6.2 0.27 11.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Retrotran_gag_2 PF14223.6 KDO29748.1 - 0.075 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type JMY PF15871.5 KDO29751.1 - 0.051 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Mpt_N PF09176.11 KDO29751.1 - 0.18 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Cys_rich_CPXG PF14255.6 KDO29752.1 - 0.21 11.5 2.9 0.22 11.5 0.4 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG dCMP_cyt_deam_1 PF00383.23 KDO29753.1 - 3.5e-16 58.9 0.8 4.5e-16 58.6 0.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KDO29753.1 - 2.2e-12 47.3 1.1 7.3e-10 39.2 0.7 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KDO29753.1 - 0.11 12.1 2.4 7.2 6.2 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PAN_4 PF14295.6 KDO29754.1 - 3e-12 46.2 14.0 5.4e-08 32.6 0.6 3.4 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 KDO29754.1 - 1.4e-07 31.4 2.4 0.014 15.3 0.1 2.8 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 KDO29754.1 - 0.025 14.7 10.1 1.7 8.8 4.0 2.6 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.12 KDO29754.1 - 1.2 9.0 9.2 0.18 11.7 0.6 2.6 3 0 0 3 3 3 0 PAN-like domain HTH_37 PF13744.6 KDO29756.1 - 0.15 12.0 0.9 3.3 7.7 0.1 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain Crystall PF00030.19 KDO29757.1 - 0.0037 17.4 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin Syncollin PF15138.6 KDO29757.1 - 0.019 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Syncollin Crystall_3 PF08964.10 KDO29757.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin GNAT_like PF18407.1 KDO29757.1 - 0.15 12.4 0.7 0.15 12.4 0.7 2.2 2 1 0 2 2 2 0 GCN5-related N-acetyltransferase like domain DUF1279 PF06916.13 KDO29758.1 - 1.3e-19 70.5 0.5 1.3e-19 70.5 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Ank_2 PF12796.7 KDO29759.1 - 9.5e-23 80.6 8.3 2e-09 37.9 0.2 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29759.1 - 1.2e-22 80.0 13.6 1.4e-05 25.5 0.1 5.9 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29759.1 - 8.3e-21 73.8 19.5 0.002 18.4 0.0 8.8 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29759.1 - 6.6e-12 44.5 13.6 1.6 9.6 0.0 9.1 7 2 3 10 10 10 3 Ankyrin repeat DUF5049 PF16468.5 KDO29759.1 - 7.7e-05 22.5 4.2 5.8 6.9 0.0 5.6 2 2 4 6 6 6 1 Domain of unknown function (DUF5049) VHL_C PF17211.3 KDO29759.1 - 0.00025 21.0 0.5 32 4.7 0.0 5.4 5 1 1 6 6 6 0 VHL box domain HHH_4 PF14490.6 KDO29759.1 - 0.016 15.2 0.6 7.7 6.6 0.1 3.6 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain Ank PF00023.30 KDO29759.1 - 0.018 15.5 2.3 80 3.9 0.9 5.9 2 1 1 3 3 3 0 Ankyrin repeat Phage_int_SAM_1 PF02899.17 KDO29759.1 - 0.091 13.1 0.3 26 5.2 0.0 3.8 3 1 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 KDO29760.1 - 2.2e-47 161.7 0.0 2.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29760.1 - 1.5e-45 155.5 0.0 1.8e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO29760.1 - 8.8e-07 28.0 0.1 1.1e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO29760.1 - 1.3e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KDO29760.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO29760.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DENN PF02141.21 KDO29760.1 - 0.034 14.1 0.8 0.062 13.2 0.8 1.3 1 0 0 1 1 1 0 DENN (AEX-3) domain APH PF01636.23 KDO29760.1 - 0.1 12.5 3.0 0.19 11.6 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Gtr1_RagA PF04670.12 KDO29761.1 - 3.6e-99 330.8 0.2 4.5e-99 330.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KDO29761.1 - 8.2e-10 38.4 0.0 3.2e-09 36.5 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KDO29761.1 - 2.7e-09 37.3 0.0 2.3e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO29761.1 - 2e-07 30.8 0.0 6.9e-07 29.0 0.0 1.9 2 1 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KDO29761.1 - 9.6e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO29761.1 - 0.011 15.7 0.2 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KDO29761.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KDO29761.1 - 0.024 14.4 0.1 0.081 12.7 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KDO29761.1 - 0.06 13.9 0.7 0.13 12.8 0.2 1.9 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KDO29761.1 - 0.071 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KDO29762.1 - 1.7e-30 106.2 36.8 1.7e-30 106.2 36.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO29762.1 - 3.9e-25 88.2 20.3 4.5e-18 64.8 3.4 3.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO29762.1 - 1.4e-14 53.8 19.0 2.8e-14 52.8 19.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase_Tyr PF07714.17 KDO29763.1 - 1.3e-81 273.7 0.0 6.5e-51 173.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO29763.1 - 2.4e-80 269.7 0.0 6.9e-52 176.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KDO29763.1 - 3.6e-08 33.1 0.0 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KDO29763.1 - 2.7e-06 26.5 0.6 6.9e-06 25.1 0.6 2.0 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO29763.1 - 0.00022 20.6 0.3 0.66 9.3 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29763.1 - 0.00036 20.5 0.2 0.14 12.1 0.1 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO29763.1 - 0.018 14.6 0.2 0.27 10.8 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 KDO29763.1 - 0.039 13.0 0.4 1.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 HA PF03457.14 KDO29764.1 - 1.1e-25 89.7 0.1 7.5e-14 51.8 0.0 3.0 3 0 0 3 3 3 2 Helicase associated domain MCD PF05292.11 KDO29765.1 - 1.6e-92 309.8 0.0 2.8e-92 308.9 0.0 1.4 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 KDO29765.1 - 5.4e-09 36.1 1.3 1.3e-08 34.9 1.3 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain SIX1_SD PF16878.5 KDO29765.1 - 0.12 12.9 0.0 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain LRR_4 PF12799.7 KDO29766.1 - 0.0008 19.8 0.6 2.2 8.8 0.0 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29766.1 - 0.0019 17.9 0.4 0.007 16.1 0.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 KDO29766.1 - 0.074 13.6 0.1 0.46 11.2 0.1 2.4 1 0 0 1 1 1 0 Leucine Rich Repeat Sulfotransfer_1 PF00685.27 KDO29766.1 - 0.15 11.5 0.3 0.25 10.8 0.3 1.3 1 0 0 1 1 1 0 Sulfotransferase domain DUF2401 PF10287.9 KDO29768.1 - 0.037 13.6 0.1 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) V-ATPase_H_N PF03224.14 KDO29769.1 - 0.00017 21.0 1.9 0.0017 17.7 1.2 2.3 2 1 0 2 2 2 1 V-ATPase subunit H NopRA1 PF16201.5 KDO29769.1 - 0.013 15.1 0.4 2.1 7.9 0.1 3.0 2 1 1 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Arm PF00514.23 KDO29769.1 - 0.023 14.8 21.1 1.2 9.3 0.0 7.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat KAP PF05804.12 KDO29769.1 - 0.034 12.3 0.1 0.065 11.4 0.1 1.4 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Aa_trans PF01490.18 KDO29770.1 - 1.3e-09 37.3 30.6 2.8e-08 32.9 30.6 2.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase_Tyr PF07714.17 KDO29771.1 - 1.6e-51 175.1 0.0 1.6e-35 122.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO29771.1 - 4.1e-35 121.4 0.0 1e-22 80.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KDO29771.1 - 2.9e-06 26.8 0.3 0.034 13.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29771.1 - 4.3e-06 26.8 10.6 0.084 12.8 0.4 4.2 3 1 1 4 4 4 3 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO29771.1 - 3e-05 23.5 0.0 0.009 15.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KDO29771.1 - 0.021 14.4 0.1 1.7 8.2 0.0 2.7 2 1 1 3 3 3 0 RIO1 family BT1 PF03092.16 KDO29772.1 - 2.3e-08 32.7 20.9 5.1e-08 31.6 0.7 3.4 3 1 0 3 3 3 3 BT1 family MFS_1 PF07690.16 KDO29772.1 - 0.0021 17.0 19.4 0.0021 17.0 19.4 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 KDO29775.1 - 1.9e-88 296.1 0.0 2.5e-52 177.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO29775.1 - 6.5e-81 271.6 0.0 6.7e-49 166.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain C2 PF00168.30 KDO29775.1 - 1.6e-07 31.5 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KDO29775.1 - 3.2e-07 29.9 0.0 0.0033 16.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO29775.1 - 5.7e-07 29.1 0.1 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29775.1 - 2.7e-05 24.2 0.1 0.17 11.8 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO29775.1 - 0.0008 19.1 0.0 0.57 9.7 0.1 2.3 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 KDO29775.1 - 0.0025 16.7 0.0 0.0069 15.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase LRR_6 PF13516.6 KDO29776.1 - 4.1e-09 35.8 3.0 0.00023 20.9 0.1 5.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 KDO29776.1 - 0.051 14.0 9.2 4.1 8.0 0.2 5.1 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29776.1 - 0.48 10.2 8.8 6.3 6.7 0.6 4.8 4 2 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 KDO29777.1 - 5.6e-08 32.2 15.5 0.1 12.7 0.0 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KDO29777.1 - 4.5e-05 23.7 7.6 0.74 10.3 0.0 6.1 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29777.1 - 0.0054 16.5 9.4 4.2 7.2 0.1 5.5 3 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KDO29778.1 - 7.2e-10 38.1 9.0 0.0018 18.1 0.2 7.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.6 KDO29778.1 - 0.0023 17.7 3.3 1.1 9.0 0.2 4.9 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO29778.1 - 0.0024 18.2 11.7 1.6 9.2 0.0 5.7 6 1 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO29778.1 - 0.005 17.2 0.7 37 5.4 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat Ank_2 PF12796.7 KDO29779.1 - 2e-29 102.0 1.7 2.9e-12 47.0 0.0 5.3 3 1 5 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29779.1 - 1.1e-16 59.3 4.8 0.025 15.1 0.0 9.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 KDO29779.1 - 5.3e-15 55.6 2.4 2.9e-05 24.5 0.0 6.1 3 2 5 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO29779.1 - 3.5e-12 46.2 8.2 0.43 11.1 0.0 8.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KDO29779.1 - 9.7e-08 32.1 11.0 0.067 13.5 0.0 7.4 5 2 3 8 8 8 4 Ankyrin repeats (many copies) PS-DH PF14765.6 KDO29781.1 - 0.017 14.4 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase LRR_6 PF13516.6 KDO29782.1 - 9.7e-09 34.6 15.5 0.00017 21.4 0.3 6.0 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 KDO29782.1 - 0.032 14.8 3.6 12 6.9 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO29782.1 - 0.094 13.2 6.8 3.6 8.2 0.3 5.3 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO29783.1 - 3.9e-07 29.6 1.9 0.34 11.1 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 KDO29783.1 - 2.7e-05 23.8 0.6 0.00018 21.2 0.1 2.7 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO29783.1 - 0.013 15.9 0.9 0.1 13.1 0.0 3.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO29784.1 - 5.5e-16 57.2 9.7 0.00027 20.7 0.0 6.7 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KDO29784.1 - 1e-05 25.8 8.2 0.0043 17.4 0.1 4.2 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO29784.1 - 0.0057 16.4 9.4 0.26 11.1 0.4 4.1 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KDO29784.1 - 0.0084 16.5 1.5 3.2 8.7 0.2 4.9 4 1 0 4 4 4 1 Leucine Rich Repeat UBM PF14377.6 KDO29785.1 - 0.038 13.5 0.6 0.088 12.3 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin binding region Pkinase PF00069.25 KDO29786.1 - 3.4e-48 164.3 0.0 4.3e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29786.1 - 1.1e-28 100.2 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO29786.1 - 1.1e-05 24.6 0.0 1.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO29786.1 - 1.8e-05 23.8 0.0 2.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO29786.1 - 2.1e-05 24.6 3.2 0.0058 16.6 1.6 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO29786.1 - 9e-05 21.9 0.3 0.00012 21.5 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO29786.1 - 0.0032 16.8 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KDO29786.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2719 PF10891.8 KDO29787.1 - 0.039 13.8 0.5 1.8 8.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2719) WW PF00397.26 KDO29787.1 - 0.22 11.7 0.9 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 WW domain DUF2719 PF10891.8 KDO29790.1 - 0.24 11.3 1.5 1.4 8.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2719) Pkinase PF00069.25 KDO29792.1 - 1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29792.1 - 4.1e-33 114.8 0.0 5.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29792.1 - 0.00046 19.6 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like COQ9 PF08511.11 KDO29793.1 - 1.3e-08 34.5 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 COQ9 RCC1 PF00415.18 KDO29794.1 - 3.1e-65 216.6 23.7 1.7e-11 44.5 0.4 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO29794.1 - 2.5e-22 78.1 34.9 1.1e-07 31.4 3.5 7.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L11_N PF03946.14 KDO29795.1 - 0.2 11.5 0.1 0.2 11.5 0.1 2.2 2 1 0 2 2 2 0 Ribosomal protein L11, N-terminal domain LpxI_C PF06230.11 KDO29797.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain Mem_trans PF03547.18 KDO29797.1 - 0.36 9.2 1.5 2.6 6.3 0.0 2.0 2 0 0 2 2 2 0 Membrane transport protein PH PF00169.29 KDO29798.1 - 9e-07 29.4 0.1 1.1e-05 25.8 0.1 2.1 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO29798.1 - 0.0013 19.1 0.6 0.031 14.7 0.3 2.3 1 1 0 2 2 2 1 Pleckstrin homology domain CCDC53 PF10152.9 KDO29798.1 - 0.92 9.9 4.0 1.5 9.2 4.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Acyltransferase PF01553.21 KDO29801.1 - 6.7e-18 64.6 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KDO29801.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus CtsR PF05848.11 KDO29804.1 - 0.079 12.9 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 CtsR N-terminal HTH domain CLIP1_ZNF PF16641.5 KDO29806.1 - 0.21 11.5 3.9 0.1 12.5 1.0 1.9 2 0 0 2 2 2 0 CLIP1 zinc knuckle Astro_capsid_N PF03115.14 KDO29807.1 - 0.64 8.6 5.5 0.73 8.4 5.5 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor GTP_EFTU PF00009.27 KDO29810.1 - 5.6e-31 107.6 0.0 1.1e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KDO29810.1 - 9e-11 42.0 0.5 2.4e-10 40.6 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO29810.1 - 2.2e-07 30.9 0.1 4.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KDO29810.1 - 0.00056 19.4 0.2 0.0012 18.3 0.2 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 KDO29810.1 - 0.0014 18.3 0.4 0.041 13.5 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KDO29810.1 - 0.0059 16.4 0.2 5.3 6.7 0.0 2.8 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KDO29810.1 - 0.048 13.6 1.4 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase RIBIOP_C PF04950.12 KDO29810.1 - 0.055 12.9 0.2 1 8.7 0.0 2.5 3 0 0 3 3 3 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal G-alpha PF00503.20 KDO29810.1 - 0.063 12.4 0.1 9.3 5.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KDO29810.1 - 0.071 12.9 0.4 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KDO29810.1 - 0.089 13.2 0.2 0.41 11.0 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain RWD PF05773.22 KDO29811.1 - 2.1e-05 24.8 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 1 RWD domain zf-RING_11 PF17123.5 KDO29811.1 - 0.006 16.3 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO29811.1 - 0.073 13.4 3.4 0.18 12.1 3.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO29811.1 - 0.13 12.3 5.2 0.29 11.2 5.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KDO29811.1 - 0.2 12.0 7.0 0.63 10.4 6.9 1.9 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KDO29811.1 - 0.54 10.3 2.9 1.4 8.9 2.9 1.7 1 1 0 1 1 1 0 zinc-RING finger domain TPR_12 PF13424.6 KDO29812.1 - 0.035 14.4 0.2 0.12 12.7 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Fer4_11 PF13247.6 KDO29812.1 - 0.11 12.7 2.4 23 5.2 0.2 3.7 4 0 0 4 4 4 0 4Fe-4S dicluster domain zf-BED PF02892.15 KDO29812.1 - 0.96 9.5 10.8 1.3 9.1 0.1 4.1 3 0 0 3 3 3 0 BED zinc finger TPR_1 PF00515.28 KDO29813.1 - 5e-31 105.2 7.9 0.0012 18.5 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KDO29813.1 - 2.1e-30 102.4 13.8 0.0052 16.8 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29813.1 - 1.5e-15 57.6 19.1 0.012 16.3 0.0 6.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KDO29813.1 - 1.4e-14 53.9 32.7 0.009 16.1 0.0 8.4 5 2 2 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KDO29813.1 - 1.8e-14 53.1 6.4 0.002 17.8 0.0 7.7 6 2 2 8 8 8 3 TPR repeat TPR_8 PF13181.6 KDO29813.1 - 4.1e-14 51.5 5.5 1.2 9.6 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29813.1 - 3.9e-09 36.9 18.1 0.0016 18.9 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29813.1 - 7.3e-08 32.6 21.3 1.1 10.3 1.1 7.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO29813.1 - 1.5e-06 28.1 0.4 20 5.9 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO29813.1 - 2.3e-06 27.8 13.3 0.071 13.8 0.0 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29813.1 - 3.2e-06 27.3 16.7 2 8.8 0.2 7.5 5 1 2 7 7 7 2 Tetratricopeptide repeat NTP_transf_2 PF01909.23 KDO29813.1 - 3.4e-05 24.0 0.1 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KDO29813.1 - 8.1e-05 22.7 0.0 0.00027 21.1 0.0 1.8 2 0 0 2 2 1 1 Cid1 family poly A polymerase TPR_20 PF14561.6 KDO29813.1 - 0.00034 20.9 4.6 0.59 10.5 0.0 5.5 4 1 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 KDO29813.1 - 0.0084 15.1 0.1 0.0084 15.1 0.1 3.8 3 2 1 4 4 3 2 NMDA receptor-regulated protein 1 Rx_N PF18052.1 KDO29813.1 - 0.022 15.0 0.4 0.074 13.3 0.4 1.9 1 0 0 1 1 1 0 Rx N-terminal domain MIT PF04212.18 KDO29813.1 - 0.024 14.7 4.6 20 5.3 0.0 4.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Hemerythrin PF01814.23 KDO29813.1 - 0.05 14.2 2.0 0.13 12.9 0.1 2.6 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain ANAPC3 PF12895.7 KDO29813.1 - 0.091 13.0 4.1 0.17 12.1 0.5 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Cwf_Cwc_15 PF04889.12 KDO29813.1 - 0.35 10.6 11.4 1 9.0 11.4 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SlyX PF04102.12 KDO29813.1 - 4.3 8.0 10.5 2.2 9.0 0.4 3.4 3 0 0 3 3 2 0 SlyX Oscp1 PF10188.9 KDO29814.1 - 1.1e-65 221.0 5.1 1.4e-65 220.7 5.1 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 FYDLN_acid PF09538.10 KDO29814.1 - 6.2 7.6 8.4 30 5.4 8.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) WW PF00397.26 KDO29815.1 - 5.3e-24 84.0 1.6 1.2e-11 44.4 0.1 2.7 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 KDO29815.1 - 3.9e-12 46.1 6.7 3.9e-12 46.1 6.7 3.2 3 1 1 4 4 4 1 FYVE zinc finger zf-LSD1 PF06943.12 KDO29815.1 - 0.00091 19.0 27.2 0.0064 16.3 4.0 4.9 4 0 0 4 4 4 2 LSD1 zinc finger DUF4727 PF15856.5 KDO29815.1 - 0.01 15.4 0.1 2.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) zinc_ribbon_5 PF13719.6 KDO29815.1 - 3.8 7.3 20.7 1.9 8.3 3.3 4.7 4 0 0 4 4 4 0 zinc-ribbon domain Ion_trans PF00520.31 KDO29816.1 - 7.5e-153 506.8 98.3 7.4e-39 133.4 19.4 5.1 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 KDO29816.1 - 1.5e-08 33.7 80.0 3.7e-06 25.9 8.1 8.6 6 3 3 9 9 9 6 Polycystin cation channel MDFI PF15316.6 KDO29816.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 MyoD family inhibitor DDE_Tnp_1_5 PF13737.6 KDO29816.1 - 0.08 13.3 0.5 34 4.8 0.0 3.3 3 0 0 3 3 3 0 Transposase DDE domain Lustrin_cystein PF14625.6 KDO29816.1 - 0.46 10.9 4.9 0.11 12.9 0.8 2.1 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain DUF4834 PF16118.5 KDO29816.1 - 0.75 10.8 0.0 0.75 10.8 0.0 7.4 8 0 0 8 8 8 0 Domain of unknown function (DUF4834) Anoctamin PF04547.12 KDO29817.1 - 5.9e-79 266.0 9.4 7.4e-79 265.7 9.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ank_2 PF12796.7 KDO29817.1 - 2.3e-14 53.8 0.2 9.4e-06 26.1 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29817.1 - 8.4e-10 39.0 0.9 0.00031 21.2 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29817.1 - 4.2e-09 35.9 4.1 0.042 14.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KDO29817.1 - 1.5e-06 28.3 5.5 0.033 14.6 0.0 5.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO29817.1 - 8.4e-06 26.0 2.4 1.4 9.3 0.2 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) zf-B_box PF00643.24 KDO29817.1 - 0.0022 18.1 1.3 0.0062 16.7 1.3 1.8 1 0 0 1 1 1 1 B-box zinc finger EGF_2 PF07974.13 KDO29819.1 - 1.8e-27 95.4 122.1 4.4e-08 33.4 5.3 10.5 10 1 0 10 10 10 9 EGF-like domain hEGF PF12661.7 KDO29819.1 - 0.0012 19.4 5.7 0.0012 19.4 5.7 9.1 9 0 0 9 9 9 3 Human growth factor-like EGF EGF PF00008.27 KDO29819.1 - 0.002 18.4 14.2 0.0034 17.7 2.6 10.2 10 0 0 10 10 10 6 EGF-like domain Dicistro_VP4 PF11492.8 KDO29819.1 - 0.021 14.8 2.3 0.066 13.2 2.3 1.8 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 UPF0444 PF15475.6 KDO29819.1 - 2.1 8.7 10.3 0.7 10.2 6.7 2.1 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Cystatin PF00031.21 KDO29820.1 - 0.013 15.7 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Cystatin domain ETF_QO PF05187.13 KDO29821.1 - 5e-37 126.2 0.1 8.1e-37 125.5 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 KDO29821.1 - 3.5e-05 23.1 0.4 0.0016 17.6 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KDO29821.1 - 5.2e-05 23.0 0.1 0.055 13.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KDO29821.1 - 0.00015 21.1 0.0 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KDO29821.1 - 0.00048 20.3 0.0 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KDO29821.1 - 0.0014 17.7 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KDO29821.1 - 0.0035 16.6 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO29821.1 - 0.009 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KDO29821.1 - 0.029 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KDO29821.1 - 0.05 12.3 0.1 0.074 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KDO29821.1 - 0.055 12.7 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KDO29821.1 - 0.076 13.6 3.7 0.087 13.4 2.3 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Pyr_redox PF00070.27 KDO29821.1 - 0.097 13.2 0.6 3.9 8.1 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UCH PF00443.29 KDO29822.1 - 1e-64 218.6 0.0 1.4e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO29822.1 - 6.9e-12 45.6 0.2 5.4e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KDO29822.1 - 4.4e-09 36.8 0.0 8.6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 DUSP domain PLAC8 PF04749.17 KDO29823.1 - 6.6e-20 72.0 15.2 8.2e-20 71.7 15.2 1.1 1 0 0 1 1 1 1 PLAC8 family 2OG-FeII_Oxy_3 PF13640.6 KDO29825.1 - 6.5e-13 49.4 0.0 1.1e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KDO29825.1 - 2e-06 28.3 0.0 3.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KDO29825.1 - 0.037 14.3 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Sirohm_synth_M PF14824.6 KDO29825.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF3662 PF12401.8 KDO29825.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Kinesin PF00225.23 KDO29826.1 - 1.4e-98 329.9 0.0 1.9e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO29826.1 - 4.5e-24 85.1 0.0 7.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding CLZ PF16526.5 KDO29826.1 - 0.021 15.2 0.8 0.16 12.3 0.1 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels I_LWEQ PF01608.17 KDO29826.1 - 0.69 10.1 8.9 8.8 6.5 2.8 2.6 1 1 0 2 2 2 0 I/LWEQ domain SlyX PF04102.12 KDO29826.1 - 1.3 9.7 3.2 12 6.6 0.3 2.8 2 0 0 2 2 2 0 SlyX ABC_tran_CTD PF16326.5 KDO29826.1 - 2.4 8.5 8.2 2 8.7 3.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pkinase PF00069.25 KDO29827.1 - 7.2e-44 150.1 0.0 9.7e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29827.1 - 1.6e-27 96.4 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO29827.1 - 0.0028 17.0 0.6 0.0057 16.0 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO29827.1 - 0.0053 15.7 0.0 0.01 14.8 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO29827.1 - 0.0054 15.6 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO29827.1 - 0.012 15.6 1.3 0.026 14.4 1.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KDO29827.1 - 0.03 13.9 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KDO29828.1 - 8.6e-53 179.3 0.0 1.1e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO29828.1 - 2.6e-49 168.0 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KDO29828.1 - 1.2e-11 44.2 8.7 4.7e-07 29.5 1.1 3.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO29828.1 - 1.2e-10 41.5 9.6 1.1e-05 25.7 0.4 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO29828.1 - 0.0003 20.9 6.0 1.4 9.7 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat Haspin_kinase PF12330.8 KDO29828.1 - 0.003 16.6 0.0 0.0088 15.0 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain SKG6 PF08693.10 KDO29828.1 - 0.011 15.1 0.3 0.026 13.9 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.23 KDO29828.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 KDO29828.1 - 5.6 7.3 13.5 2.6 8.3 0.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Aa_trans PF01490.18 KDO29830.1 - 6e-32 110.8 29.0 7.4e-18 64.4 14.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pkinase PF00069.25 KDO29831.1 - 2e-100 335.5 0.0 3.6e-49 167.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29831.1 - 1e-55 188.9 0.0 2.1e-27 96.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO29831.1 - 3.2e-10 39.5 0.0 0.00028 20.0 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 KDO29831.1 - 1.4e-09 37.6 0.0 0.00088 18.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29831.1 - 3.3e-09 37.0 4.5 0.0082 16.1 0.0 4.4 3 2 2 5 5 5 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO29831.1 - 2e-07 30.1 0.0 0.0041 16.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KDO29831.1 - 3.5e-05 23.5 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Kinase-like PF14531.6 KDO29831.1 - 0.00067 19.1 0.1 0.061 12.6 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KDO29831.1 - 0.014 15.0 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase TFIIF_beta PF02270.15 KDO29831.1 - 0.018 15.1 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain Alg6_Alg8 PF03155.15 KDO29833.1 - 1e-131 440.3 29.8 1.3e-131 439.9 29.8 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Pkinase PF00069.25 KDO29834.1 - 1.8e-43 148.9 0.0 2.1e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29834.1 - 4.9e-26 91.6 0.0 6.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO29834.1 - 0.0012 17.8 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO29834.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2087 PF09860.9 KDO29834.1 - 0.17 12.1 0.0 0.7 10.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) zf-C3HC4_3 PF13920.6 KDO29835.1 - 3e-12 46.2 11.8 5.8e-12 45.3 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 KDO29835.1 - 3.1e-11 43.6 0.0 0.00012 22.5 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO29835.1 - 4.8e-10 39.9 0.1 1.1e-09 38.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29835.1 - 2.2e-08 33.7 0.1 0.0091 16.4 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO29835.1 - 2.4e-06 27.7 0.5 0.0078 16.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 KDO29835.1 - 9.2e-06 25.9 12.4 2.5e-05 24.5 12.4 1.8 1 0 0 1 1 1 1 Ring finger domain Ank PF00023.30 KDO29835.1 - 3.2e-05 24.2 0.8 0.33 11.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 KDO29835.1 - 0.00018 21.3 12.3 0.00039 20.2 12.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KDO29835.1 - 0.62 10.0 17.4 0.072 12.9 13.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO29835.1 - 1.5 8.9 11.6 4 7.5 11.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KDO29835.1 - 3.5 7.5 10.7 9.5 6.1 10.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KDO29836.1 - 7.9e-14 51.2 10.7 2.2e-13 49.8 10.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 KDO29836.1 - 1.2e-11 45.0 0.0 2.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO29836.1 - 3.7e-11 43.3 0.3 1.1e-10 41.8 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO29836.1 - 8.8e-11 41.8 0.7 4e-05 23.8 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29836.1 - 9.7e-08 31.7 0.2 0.047 14.2 0.1 3.2 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 KDO29836.1 - 1.4e-06 28.5 0.6 0.044 14.3 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeat zf-RING_2 PF13639.6 KDO29836.1 - 2.6e-06 27.6 9.5 9.5e-06 25.8 9.5 2.1 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO29836.1 - 3.4e-06 26.8 9.8 8.9e-06 25.5 9.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KDO29836.1 - 0.0013 18.6 9.6 0.0036 17.1 9.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO29836.1 - 0.0017 18.2 10.9 0.0017 18.2 10.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO29836.1 - 0.0087 16.0 9.2 0.0087 16.0 9.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 KDO29836.1 - 0.014 15.2 7.9 0.038 13.8 7.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KDO29836.1 - 2.3 8.3 9.0 4.8 7.3 1.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 KDO29836.1 - 7.6 6.8 14.4 2.8 8.2 10.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING BAH PF01426.18 KDO29837.1 - 9.8e-11 41.6 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain Ank_2 PF12796.7 KDO29838.1 - 1.5e-24 86.4 0.0 1.2e-12 48.2 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 KDO29838.1 - 1.1e-13 50.9 10.3 1.1e-13 50.9 10.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KDO29838.1 - 1.4e-11 44.4 0.5 2.9e-06 27.5 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29838.1 - 4e-11 43.2 0.2 8.5e-10 39.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO29838.1 - 3.7e-09 36.6 2.6 0.0016 18.8 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO29838.1 - 5.4e-09 35.6 0.5 0.00029 21.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 KDO29838.1 - 5.8e-05 23.3 10.9 0.00016 21.9 10.9 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO29838.1 - 0.0012 18.6 11.9 0.0012 18.6 11.9 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO29838.1 - 0.0038 17.2 10.0 0.008 16.1 10.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO29838.1 - 0.014 15.3 10.1 0.027 14.3 10.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO29838.1 - 0.029 14.2 11.9 0.06 13.2 11.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KDO29838.1 - 0.29 11.0 8.2 0.57 10.0 8.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SPATA3 PF15662.5 KDO29838.1 - 0.29 11.8 7.1 0.58 10.8 7.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family zf-C3HC4_4 PF15227.6 KDO29838.1 - 4.7 7.4 11.5 10 6.4 11.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KDO29839.1 - 5.4e-76 255.4 0.2 6.5e-76 255.2 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29839.1 - 1.3e-39 136.1 0.2 1.7e-39 135.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29839.1 - 3.5e-09 36.4 0.1 1.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KDO29839.1 - 1e-06 29.3 3.2 1e-06 29.3 3.2 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KDO29839.1 - 3.2e-06 26.2 0.0 4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO29839.1 - 7.4e-05 21.9 0.2 0.00011 21.3 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KDO29839.1 - 0.00047 19.8 0.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KDO29839.1 - 0.0022 17.4 0.2 0.0046 16.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29839.1 - 0.0037 17.2 0.0 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1635 PF07795.11 KDO29840.1 - 2.3 8.0 12.9 3.8 7.3 10.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) CENP-B_dimeris PF09026.10 KDO29840.1 - 6.4 7.2 18.8 2.4 8.6 9.0 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AAA_11 PF13086.6 KDO29841.1 - 5e-60 203.5 0.6 5e-60 203.5 0.6 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KDO29841.1 - 7.9e-36 123.6 0.0 1.2e-23 83.8 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KDO29841.1 - 6e-14 52.2 2.6 7e-12 45.5 0.3 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KDO29841.1 - 3.8e-09 37.0 1.4 2.4e-08 34.4 0.3 2.7 2 1 0 2 2 2 1 AAA domain zf-AN1 PF01428.16 KDO29841.1 - 4.9e-08 33.0 3.9 8.7e-08 32.2 3.9 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Helicase_RecD PF05127.14 KDO29841.1 - 1.9e-06 27.8 0.9 8.5e-05 22.5 0.9 2.7 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 KDO29841.1 - 3.9e-06 27.0 0.0 1.5e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO29841.1 - 3.9e-05 23.5 1.0 0.00034 20.4 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KDO29841.1 - 0.00017 21.4 1.0 0.17 11.6 0.2 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KDO29841.1 - 0.00033 21.1 3.0 0.013 15.9 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO29841.1 - 0.00036 20.8 0.1 0.004 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KDO29841.1 - 0.00076 19.0 0.5 0.0031 17.0 0.5 2.0 1 1 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KDO29841.1 - 0.0014 17.9 1.0 0.032 13.5 0.5 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KDO29841.1 - 0.0016 18.9 0.6 0.0045 17.4 0.6 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KDO29841.1 - 0.0034 16.5 0.0 0.0075 15.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KDO29841.1 - 0.0043 17.0 0.5 0.016 15.2 0.3 2.1 1 1 1 2 2 2 1 Flavivirus DEAD domain UvrD-helicase PF00580.21 KDO29841.1 - 0.0082 15.7 0.2 0.0082 15.7 0.2 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 KDO29841.1 - 0.0095 15.5 3.5 0.061 12.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain PIF1 PF05970.14 KDO29841.1 - 0.028 13.6 0.0 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Rad17 PF03215.15 KDO29841.1 - 0.041 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 KDO29841.1 - 0.041 13.5 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KDO29841.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KDO29841.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 KDO29841.1 - 0.062 12.9 0.8 0.15 11.7 0.1 2.0 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KDO29841.1 - 0.062 13.8 0.0 0.45 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KDO29841.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.3 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KDO29841.1 - 0.14 12.5 0.0 0.5 10.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase LRR_4 PF12799.7 KDO29842.1 - 1.2e-05 25.5 0.0 0.00061 20.1 0.0 2.7 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO29842.1 - 0.097 12.8 0.5 20 5.5 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat PSI_integrin PF17205.3 KDO29842.1 - 0.14 11.9 0.5 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Integrin plexin domain bZIP_1 PF00170.21 KDO29843.1 - 1.7 8.8 10.1 0.22 11.6 6.0 1.6 2 0 0 2 2 2 0 bZIP transcription factor Proteasom_PSMB PF10508.9 KDO29844.1 - 3.4e-35 121.5 0.0 9e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Neurochondrin PF05536.11 KDO29844.1 - 0.0023 16.4 0.3 0.6 8.4 0.0 2.6 3 0 0 3 3 3 2 Neurochondrin Adaptin_N PF01602.20 KDO29844.1 - 0.017 13.7 0.1 0.047 12.3 0.0 1.5 1 1 1 2 2 2 0 Adaptin N terminal region RICTOR_V PF14668.6 KDO29844.1 - 0.088 13.1 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 KDO29844.1 - 1.9 8.9 5.6 35 5.0 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat TPR_7 PF13176.6 KDO29845.1 - 1.5e-21 74.7 5.6 0.00079 19.3 0.0 6.2 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO29845.1 - 1e-18 66.3 11.2 3.3e-05 23.5 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO29845.1 - 1.5e-17 62.2 13.7 0.00021 21.1 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO29845.1 - 5.8e-17 60.8 2.3 0.0063 16.8 0.0 5.4 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29845.1 - 1.7e-16 59.0 6.7 7.7e-05 22.6 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO29845.1 - 2.5e-16 59.1 9.9 9.6e-05 22.0 0.1 5.3 5 0 0 5 5 5 4 TPR repeat TPR_14 PF13428.6 KDO29845.1 - 2e-14 53.0 14.5 0.00021 21.8 0.0 5.8 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29845.1 - 8.9e-12 45.4 6.8 3.8e-05 24.1 0.7 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KDO29845.1 - 2.1e-10 40.3 9.8 7.1e-06 25.4 1.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29845.1 - 9.1e-10 39.0 14.9 7.2e-05 23.3 0.9 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29845.1 - 1.8e-09 37.7 13.8 0.00045 20.5 0.0 4.6 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.6 KDO29845.1 - 1.2e-08 35.0 4.7 0.027 14.6 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO29845.1 - 1.1e-06 28.8 11.4 0.1 13.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO29845.1 - 1.2e-05 25.0 15.2 1.3 9.0 0.0 6.7 6 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO29845.1 - 6.5e-05 23.1 6.0 0.11 12.8 0.1 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KDO29845.1 - 0.00049 20.4 10.0 0.83 10.0 2.2 4.0 1 1 2 3 3 3 2 Tetratricopeptide repeat MAS20 PF02064.15 KDO29845.1 - 0.0034 17.5 0.5 0.0075 16.4 0.1 1.8 2 0 0 2 2 1 1 MAS20 protein import receptor TOM20_plant PF06552.12 KDO29845.1 - 0.0047 16.7 0.9 0.17 11.6 0.2 2.3 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 DUF2989 PF11207.8 KDO29845.1 - 0.015 15.0 5.5 0.3 10.8 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) PPR_long PF17177.4 KDO29845.1 - 0.016 14.6 0.8 0.016 14.6 0.8 2.4 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 KDO29845.1 - 0.02 15.3 6.8 7.8 6.9 0.7 3.1 1 1 2 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.10 KDO29845.1 - 0.031 13.3 0.5 0.23 10.4 0.2 1.9 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 KDO29845.1 - 0.031 14.5 0.1 0.68 10.3 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Imm30 PF15565.6 KDO29845.1 - 0.057 13.5 0.2 0.41 10.8 0.0 2.3 2 1 0 2 2 2 0 Immunity protein 30 TPR_3 PF07720.12 KDO29845.1 - 0.067 13.2 12.7 0.44 10.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2959 PF11172.8 KDO29845.1 - 0.1 12.8 2.1 23 5.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) Alkyl_sulf_dimr PF14863.6 KDO29845.1 - 0.42 11.1 7.6 4.1 7.9 1.3 3.0 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 KDO29845.1 - 0.69 10.7 8.0 5.1 8.0 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat HVSL PF09749.9 KDO29846.1 - 5e-34 117.8 0.0 6.7e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein HNOBA PF07701.14 KDO29846.1 - 0.0073 15.8 0.0 0.33 10.4 0.0 2.1 1 1 0 1 1 1 1 Heme NO binding associated Glyc_hyd_38C_2 PF18230.1 KDO29846.1 - 0.094 12.8 1.2 0.37 10.9 1.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain HEAT PF02985.22 KDO29847.1 - 2.1e-31 105.3 22.0 0.0015 18.7 0.0 13.0 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 KDO29847.1 - 2.6e-22 79.0 8.5 0.0096 16.3 0.0 7.9 2 1 3 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO29847.1 - 1.9e-11 44.4 0.1 0.46 11.1 0.0 6.0 1 1 5 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO29847.1 - 1.2e-09 38.5 2.1 0.1 12.6 0.1 5.1 1 1 4 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO29847.1 - 8.6e-08 32.5 8.6 0.044 14.3 0.0 7.4 7 1 1 8 8 8 3 HEAT-like repeat Adaptin_N PF01602.20 KDO29847.1 - 3.1e-06 26.0 1.2 0.021 13.4 0.3 4.0 2 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 KDO29847.1 - 0.0063 16.1 0.4 2.7 7.5 0.0 3.1 2 2 0 2 2 2 2 CLASP N terminal IFRD PF05004.13 KDO29847.1 - 0.024 13.7 0.9 1.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 KDO29847.1 - 0.044 13.3 0.2 0.099 12.2 0.2 1.6 1 0 0 1 1 1 0 Tti2 family LRV PF01816.17 KDO29847.1 - 2.9 8.5 7.5 84 3.9 0.0 5.2 4 0 0 4 4 4 0 Leucine rich repeat variant WD40 PF00400.32 KDO29848.1 - 3.3e-15 56.2 8.5 0.00062 20.5 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.22 KDO29848.1 - 7.7e-05 22.6 17.1 0.34 11.3 0.8 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KDO29848.1 - 0.00048 20.5 4.7 0.42 11.0 0.1 4.8 3 2 1 5 5 5 2 HEAT repeats ANAPC4_WD40 PF12894.7 KDO29848.1 - 0.00061 20.0 0.5 1.1 9.6 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Tti2 PF10521.9 KDO29848.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Tti2 family BT1 PF03092.16 KDO29849.1 - 1.4e-12 46.7 16.0 9.4e-11 40.6 1.3 3.2 2 1 1 3 3 3 3 BT1 family PUCC PF03209.15 KDO29849.1 - 0.00049 19.2 0.3 0.00049 19.2 0.3 2.7 2 1 0 2 2 2 1 PUCC protein DUF1541 PF07563.11 KDO29849.1 - 0.025 14.5 1.4 0.052 13.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) BT1 PF03092.16 KDO29850.1 - 9e-11 40.7 10.9 5.3e-08 31.5 0.4 3.3 2 1 1 3 3 3 3 BT1 family PUCC PF03209.15 KDO29850.1 - 7.7e-06 25.2 9.6 9.3e-05 21.6 1.2 3.0 2 2 0 2 2 2 2 PUCC protein Acatn PF13000.7 KDO29850.1 - 0.00024 19.7 2.3 0.11 11.0 0.1 2.2 2 0 0 2 2 2 2 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 KDO29850.1 - 0.055 12.3 13.3 0.038 12.8 9.4 2.5 2 1 0 2 2 2 0 MFS_1 like family CrgA PF06781.12 KDO29850.1 - 0.16 12.0 0.4 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Cell division protein CrgA IFT57 PF10498.9 KDO29851.1 - 0.0094 15.0 6.2 0.04 12.9 2.2 2.3 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 DUF885 PF05960.11 KDO29851.1 - 0.013 15.2 11.6 0.024 14.3 11.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) CLZ PF16526.5 KDO29851.1 - 0.019 15.3 11.3 0.049 14.0 0.4 3.5 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KxDL PF10241.9 KDO29851.1 - 0.033 14.5 5.1 0.086 13.1 0.8 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 KDO29851.1 - 0.26 11.3 15.7 0.14 12.1 8.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 KDO29851.1 - 0.31 11.0 5.8 7.1 6.6 0.2 2.6 2 0 0 2 2 2 0 Prefoldin subunit Cep57_MT_bd PF06657.13 KDO29851.1 - 4.5 7.8 13.5 0.1 13.1 1.2 3.7 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.11 KDO29851.1 - 4.6 7.7 5.8 5.8 7.4 0.8 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Muted PF14942.6 KDO29851.1 - 4.8 7.5 15.7 4 7.8 2.6 3.1 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 KDO29851.1 - 5.5 7.0 8.1 4.8 7.2 1.4 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 KDO29851.1 - 6.4 7.3 15.5 3 8.4 6.0 4.1 4 1 0 4 4 3 0 Spectrin repeat Pkinase PF00069.25 KDO29852.1 - 8.6e-66 222.0 0.0 1e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29852.1 - 7.2e-35 120.5 0.0 9.6e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29852.1 - 3.8e-10 39.6 0.0 1.6e-08 34.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KDO29852.1 - 9.8e-06 25.1 0.1 1.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO29852.1 - 3.3e-05 22.8 0.0 4.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Toprim_3 PF13362.6 KDO29852.1 - 0.0002 21.6 1.1 0.00057 20.2 1.1 1.7 1 0 0 1 1 1 1 Toprim domain FTA2 PF13095.6 KDO29852.1 - 0.0011 18.6 0.0 0.023 14.3 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO29852.1 - 0.0053 16.7 0.7 0.031 14.2 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO29852.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KDO29852.1 - 0.012 15.3 0.1 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 RIO1 family UPRTase PF14681.6 KDO29853.1 - 2.3e-67 226.5 0.1 3.8e-67 225.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Trp_repressor PF01371.19 KDO29853.1 - 0.00025 21.1 0.0 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 Trp repressor protein Pribosyltran PF00156.27 KDO29853.1 - 0.0015 18.1 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF693 PF05113.13 KDO29853.1 - 0.04 13.2 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) UxaE PF16257.5 KDO29853.1 - 0.046 12.4 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 tagaturonate epimerase Meis_PKNOX_N PF16493.5 KDO29853.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 TPR_1 PF00515.28 KDO29854.1 - 4.3e-24 83.3 0.8 1.9e-06 27.4 0.0 3.5 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO29854.1 - 2.5e-20 70.9 1.7 5.3e-05 23.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO29854.1 - 2.5e-15 55.9 1.6 1.1e-05 25.0 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KDO29854.1 - 7.9e-13 47.5 0.2 0.0016 18.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29854.1 - 1.1e-10 41.6 0.9 1.8e-07 31.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO29854.1 - 2.9e-07 31.0 0.0 0.00042 20.9 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO29854.1 - 6.7e-07 29.3 2.5 0.002 18.4 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29854.1 - 1.8e-06 28.3 0.3 0.032 15.0 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO29854.1 - 2.9e-06 27.7 0.7 0.00079 19.9 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO29854.1 - 5.5e-06 26.4 0.5 0.00068 19.7 0.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29854.1 - 6.2e-05 22.7 0.1 4.9 7.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO29854.1 - 0.00015 22.2 0.0 2.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5588 PF17826.1 KDO29854.1 - 0.0013 17.7 0.4 0.0029 16.5 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5588) ANAPC3 PF12895.7 KDO29854.1 - 0.0017 18.5 3.1 0.016 15.4 3.1 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KDO29854.1 - 0.0042 17.2 0.1 6.4 6.8 0.0 3.2 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) eIF3_N PF09440.10 KDO29854.1 - 0.018 15.5 0.2 0.018 15.5 0.2 1.6 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain TPR_15 PF13429.6 KDO29854.1 - 0.041 13.1 0.2 0.27 10.4 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO29854.1 - 0.087 12.9 0.2 0.63 10.2 0.0 2.5 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat IQ PF00612.27 KDO29855.1 - 1.3e-05 24.6 0.0 5e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3584 PF12128.8 KDO29855.1 - 0.012 13.2 26.3 0.016 12.8 26.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.21 KDO29855.1 - 0.12 11.9 34.2 0.59 9.7 10.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein hnRNP_Q_AcD PF18360.1 KDO29855.1 - 0.13 12.2 0.9 0.95 9.5 0.1 2.8 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain OmpH PF03938.14 KDO29855.1 - 2.4 8.5 34.1 1.7 8.9 12.4 2.5 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ApoO PF09769.9 KDO29855.1 - 2.8 7.9 6.5 1.3 9.0 1.1 2.6 2 1 0 2 2 2 0 Apolipoprotein O FlaC_arch PF05377.11 KDO29855.1 - 3.1 8.3 9.4 24 5.4 0.2 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KDO29855.1 - 3.1 6.6 35.0 2.5 6.9 18.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KDO29855.1 - 7.9 6.5 12.7 4.6 7.3 5.2 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.19 KDO29855.1 - 9.4 5.9 27.0 1.7 8.3 5.4 3.3 1 1 2 3 3 3 0 GrpE TIG PF01833.24 KDO29856.1 - 5.2e-23 80.9 29.9 7.9e-10 38.7 3.0 5.8 6 1 0 6 6 6 3 IPT/TIG domain Ephrin_rec_like PF07699.13 KDO29856.1 - 1.4e-07 31.1 79.6 8.8e-05 22.2 5.6 10.5 7 3 3 10 10 10 5 Putative ephrin-receptor like TIG_plexin PF17960.1 KDO29856.1 - 0.0056 16.6 0.0 16 5.6 0.0 3.7 3 0 0 3 3 3 2 TIG domain F-box-like PF12937.7 KDO29857.1 - 3.4e-06 26.8 1.1 7.5e-06 25.8 1.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO29857.1 - 0.048 13.5 0.3 0.048 13.5 0.3 1.8 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KDO29857.1 - 0.049 13.5 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 F-box WD40 PF00400.32 KDO29858.1 - 2.7e-28 97.6 12.1 4.6e-07 30.4 0.0 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29858.1 - 2.6e-14 53.3 0.4 0.014 15.7 0.1 6.1 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KDO29858.1 - 0.0022 17.6 1.0 0.0038 16.8 1.0 1.3 1 0 0 1 1 1 1 PQQ-like domain Speriolin_N PF15058.6 KDO29858.1 - 0.0028 17.8 0.3 0.007 16.5 0.3 1.7 2 0 0 2 2 2 1 Speriolin N terminus Cnn_1N PF07989.11 KDO29858.1 - 0.021 15.0 1.2 0.1 12.7 1.7 1.8 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 TolA_bind_tri PF16331.5 KDO29858.1 - 0.023 14.7 0.5 0.071 13.2 0.1 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF2415 PF10313.9 KDO29858.1 - 0.12 12.3 0.0 0.65 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Sacchrp_dh_NADP PF03435.18 KDO29858.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IFP_35_N PF07334.13 KDO29858.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus IKI3 PF04762.12 KDO29858.1 - 0.17 9.8 1.1 1.6 6.6 0.6 2.0 2 0 0 2 2 2 0 IKI3 family bZIP_1 PF00170.21 KDO29858.1 - 0.27 11.4 1.9 0.65 10.1 1.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 KDO29858.1 - 1.2 9.5 10.5 3.9 7.8 6.0 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 KDO29858.1 - 1.7 8.5 4.0 0.48 10.2 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 KDO29858.1 - 3.2 7.9 6.9 1.6 8.9 1.6 2.7 3 0 0 3 3 3 0 Sperm tail C-terminal domain WD40 PF00400.32 KDO29859.1 - 5.4e-21 74.5 13.8 0.0001 23.0 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29859.1 - 3.3e-08 33.7 1.2 0.072 13.4 0.1 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO29859.1 - 0.00034 19.4 0.1 0.64 8.6 0.0 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KDO29859.1 - 0.0033 16.4 0.2 0.8 8.6 0.0 2.8 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C1 PF00112.23 KDO29860.1 - 2.1e-49 168.6 2.1 5.1e-49 167.3 2.1 1.6 1 1 1 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KDO29860.1 - 5.3e-15 55.6 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF4756 PF15948.5 KDO29860.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) HIT PF01230.23 KDO29861.1 - 3.3e-28 98.3 0.0 4.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KDO29861.1 - 1.2e-19 70.9 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF373 PF04123.13 KDO29862.1 - 0.21 11.0 1.2 1.8 7.9 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF3040 PF11239.8 KDO29862.1 - 0.22 11.8 6.4 0.37 11.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) DUF1279 PF06916.13 KDO29863.1 - 3.1e-07 30.9 4.6 4.2e-06 27.2 4.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2798 PF11391.8 KDO29863.1 - 0.0017 18.3 0.9 0.0033 17.4 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2798) PhnA_Zn_Ribbon PF08274.12 KDO29864.1 - 0.4 10.7 3.1 0.25 11.3 1.2 1.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon FAA_hydrolase PF01557.18 KDO29865.1 - 5.6e-57 192.9 0.0 6.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KDO29865.1 - 0.048 13.5 0.2 0.14 12.0 0.2 1.8 1 0 0 1 1 1 0 KH domain IQ PF00612.27 KDO29866.1 - 0.00071 19.2 0.9 0.0041 16.8 0.9 2.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1043 PF06295.12 KDO29866.1 - 0.18 11.8 1.0 0.37 10.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Rpn3_C PF08375.11 KDO29869.1 - 6.1e-29 100.2 1.2 1.1e-28 99.4 1.2 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KDO29869.1 - 6.4e-22 78.0 0.1 1.9e-20 73.3 0.0 2.5 2 0 0 2 2 2 1 PCI domain DUF1548 PF07579.11 KDO29869.1 - 0.035 14.5 1.1 5.3 7.4 0.1 2.7 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1548) CODH_A_N PF18537.1 KDO29869.1 - 0.036 14.1 0.0 0.86 9.7 0.0 2.8 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Carboxyl_trans PF01039.22 KDO29870.1 - 2.6e-194 646.5 0.2 3.1e-194 646.2 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KDO29870.1 - 0.0014 18.2 0.4 0.0082 15.7 0.1 2.2 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) EstA_Ig_like PF18435.1 KDO29871.1 - 0.088 13.0 0.4 0.11 12.7 0.4 1.1 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain RIH_assoc PF08454.11 KDO29872.1 - 1.2e-19 70.0 0.3 2.8e-18 65.6 0.1 2.8 2 0 0 2 2 2 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 KDO29872.1 - 3.6e-17 62.5 6.6 3.5e-09 36.4 1.2 3.4 3 0 0 3 3 3 2 RIH domain MIR PF02815.19 KDO29872.1 - 4.9e-10 39.5 0.1 3.6e-05 23.7 0.0 3.7 2 1 2 4 4 4 2 MIR domain Ins145_P3_rec PF08709.11 KDO29872.1 - 1.9e-09 37.0 0.0 4.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.6 KDO29872.1 - 0.06 14.1 0.0 2.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ion_trans PF00520.31 KDO29873.1 - 3e-06 26.6 6.0 4e-06 26.2 6.0 1.1 1 0 0 1 1 1 1 Ion transport protein Aminotran_5 PF00266.19 KDO29874.1 - 9.6e-23 80.7 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KDO29874.1 - 4.3e-05 22.2 0.0 5.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KDO29874.1 - 4.9e-05 22.8 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family STE2 PF02116.15 KDO29875.1 - 0.00038 19.9 3.6 0.00038 19.9 3.6 1.5 2 0 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR Trep_Strep PF09605.10 KDO29875.1 - 0.076 13.0 5.2 0.18 11.7 5.2 1.6 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) MTABC_N PF16185.5 KDO29875.1 - 0.19 11.2 7.4 0.37 10.3 2.7 2.1 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Zip PF02535.22 KDO29877.1 - 1.7e-11 43.9 12.9 4.7e-10 39.2 5.0 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1453 PF07301.11 KDO29877.1 - 0.046 13.7 2.8 0.049 13.6 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1453) Tmemb_14 PF03647.13 KDO29877.1 - 0.41 11.4 0.1 0.41 11.4 0.1 3.1 3 1 0 3 3 3 0 Transmembrane proteins 14C Acyl_transf_3 PF01757.22 KDO29877.1 - 4.8 6.2 15.3 0.14 11.2 4.5 2.8 2 1 0 3 3 3 0 Acyltransferase family Pkinase PF00069.25 KDO29878.1 - 1.9e-10 40.6 0.0 1.1e-08 34.8 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29878.1 - 4.7e-09 35.9 0.0 6.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase HutP PF09021.11 KDO29878.1 - 0.082 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 HutP HAP1_N PF04849.13 KDO29879.1 - 0.0077 15.5 0.3 0.012 14.8 0.3 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.9 KDO29879.1 - 0.044 13.8 0.6 0.044 13.8 0.6 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KDO29879.1 - 0.24 12.1 5.8 0.12 13.0 2.4 2.4 2 1 0 2 2 2 0 SlyX CENP-Q PF13094.6 KDO29879.1 - 0.35 11.1 7.9 0.043 14.0 3.0 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lzipper-MIP1 PF14389.6 KDO29879.1 - 5.5 7.4 7.2 2.8 8.3 1.9 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.11 KDO29879.1 - 6.8 6.9 13.9 0.24 11.6 6.9 1.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.6 KDO29879.1 - 7 7.2 9.2 27 5.3 3.9 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Vezatin PF12632.7 KDO29880.1 - 8.2e-07 28.7 0.3 8.2e-07 28.7 0.3 1.7 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Mating_N PF12731.7 KDO29880.1 - 1.4 9.0 4.0 0.54 10.4 0.5 2.2 3 0 0 3 3 3 0 Mating-type protein beta 1 Mito_fiss_reg PF05308.11 KDO29880.1 - 1.9 8.5 5.4 0.36 10.9 0.3 2.1 1 1 2 3 3 3 0 Mitochondrial fission regulator AAA PF00004.29 KDO29881.1 - 8.3e-30 103.9 0.0 3.1e-21 76.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO29881.1 - 4.2e-07 30.5 0.0 0.00011 22.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO29881.1 - 2.3e-05 24.7 0.7 0.00022 21.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KDO29881.1 - 0.00049 20.1 0.1 0.037 14.0 0.1 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KDO29881.1 - 0.00054 19.9 0.2 0.44 10.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KDO29881.1 - 0.0015 18.1 0.2 0.074 12.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KDO29881.1 - 0.0028 17.7 0.0 0.0079 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KDO29881.1 - 0.0035 17.1 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zot PF05707.12 KDO29881.1 - 0.0084 15.8 0.1 0.031 13.9 0.0 1.9 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) Sigma54_activat PF00158.26 KDO29881.1 - 0.0084 15.8 0.4 4.9 6.8 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 KDO29881.1 - 0.0095 16.1 0.1 0.15 12.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 KDO29881.1 - 0.012 16.2 0.0 4.8 7.7 0.0 3.6 4 0 0 4 4 4 0 ABC transporter DUF815 PF05673.13 KDO29881.1 - 0.013 14.7 0.1 0.69 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KDO29881.1 - 0.015 15.3 0.1 0.98 9.3 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_2 PF07724.14 KDO29881.1 - 0.022 14.9 3.6 0.38 10.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KDO29881.1 - 0.032 14.2 0.0 1.2 9.0 0.0 3.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KDO29881.1 - 0.032 14.6 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KDO29881.1 - 0.035 13.8 0.0 0.55 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO29881.1 - 0.042 14.4 0.0 10 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KDO29881.1 - 0.058 13.7 0.6 0.28 11.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO29881.1 - 0.062 13.0 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KDO29881.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KDO29881.1 - 0.088 12.4 1.5 0.18 11.4 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KDO29881.1 - 0.15 11.8 2.4 8.1 6.3 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TFIIF_alpha PF05793.12 KDO29881.1 - 5.1 5.6 8.7 8.4 4.8 8.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Symplekin_C PF12295.8 KDO29883.1 - 6.9e-41 140.4 4.2 2.4e-40 138.6 4.2 1.9 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KDO29883.1 - 5.9e-10 39.2 0.1 1.3e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) WW PF00397.26 KDO29884.1 - 1.5e-05 24.9 5.9 0.0026 17.8 0.2 2.7 2 0 0 2 2 2 2 WW domain zf-B_box PF00643.24 KDO29884.1 - 0.0005 20.2 3.5 0.0005 20.2 3.5 6.2 5 1 1 6 6 6 4 B-box zinc finger IQ PF00612.27 KDO29884.1 - 0.014 15.1 0.6 0.014 15.1 0.6 19.0 16 2 3 19 19 19 0 IQ calmodulin-binding motif DSPc PF00782.20 KDO29885.1 - 1e-27 96.5 0.0 1.2e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO29885.1 - 0.00023 20.8 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KDO29885.1 - 0.002 18.4 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Pkinase PF00069.25 KDO29886.1 - 2.6e-61 207.3 0.0 3.3e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29886.1 - 9.6e-26 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO29886.1 - 5.1e-05 23.3 0.1 0.0085 16.0 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KDO29886.1 - 0.0039 16.9 0.0 0.39 10.3 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KDO29886.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO29886.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO29886.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cellulase PF00150.18 KDO29887.1 - 1e-20 74.4 4.6 1.4e-20 73.9 4.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ZapB PF06005.12 KDO29888.1 - 0.0078 16.6 8.9 0.0078 16.6 8.9 1.9 2 0 0 2 2 2 1 Cell division protein ZapB Nup54 PF13874.6 KDO29888.1 - 0.014 15.5 4.2 0.014 15.5 4.2 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2959 PF11172.8 KDO29888.1 - 0.027 14.6 4.2 0.027 14.6 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Rootletin PF15035.6 KDO29888.1 - 0.028 14.5 8.6 0.051 13.6 8.6 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CLZ PF16526.5 KDO29888.1 - 0.069 13.5 6.2 0.17 12.3 6.2 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Occludin_ELL PF07303.13 KDO29888.1 - 0.15 12.8 3.6 1.7 9.4 0.0 2.4 2 0 0 2 2 2 0 Occludin homology domain HAGH_C PF16123.5 KDO29888.1 - 0.34 11.5 4.0 1 9.9 1.0 2.5 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Sec2p PF06428.11 KDO29888.1 - 0.36 10.8 11.3 3.7 7.6 11.5 2.3 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 KDO29888.1 - 0.37 11.5 7.0 0.38 11.4 4.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 KDO29888.1 - 0.38 11.2 9.0 0.099 13.1 5.0 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF87 PF01935.17 KDO29888.1 - 0.42 10.7 2.6 1.7 8.7 2.6 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain Mto2_bdg PF12808.7 KDO29888.1 - 0.46 10.8 10.6 1.3 9.3 1.6 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc24 PF08286.11 KDO29888.1 - 0.68 10.2 6.6 0.37 11.0 4.4 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 KDO29888.1 - 1.8 7.3 13.1 0.64 8.9 8.5 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2408 PF10303.9 KDO29888.1 - 4.5 7.9 12.1 1 9.9 8.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DivIC PF04977.15 KDO29888.1 - 8.3 6.3 12.0 1.7 8.5 8.1 1.9 2 0 0 2 2 2 0 Septum formation initiator Cellulase PF00150.18 KDO29889.1 - 3.5e-21 75.9 6.0 4.8e-21 75.4 6.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short_C2 PF13561.6 KDO29891.1 - 5.6e-48 163.5 0.0 6.8e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO29891.1 - 1.5e-47 161.6 0.0 1.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO29891.1 - 7.1e-12 45.6 0.3 1.6e-11 44.5 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO29891.1 - 5e-05 22.9 0.0 8.5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KDO29891.1 - 0.0023 17.0 0.0 0.014 14.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KDO29891.1 - 0.029 13.5 0.2 0.3 10.2 0.2 2.1 1 1 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KDO29891.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UCH PF00443.29 KDO29892.1 - 1.3e-17 64.2 0.0 3e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO29892.1 - 7.2e-12 45.5 0.0 1.3e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2621 PF11084.8 KDO29892.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) UQ_con PF00179.26 KDO29893.1 - 4.1e-43 146.4 0.0 4.6e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme B2-adapt-app_C PF09066.10 KDO29894.1 - 1.4e-19 70.2 0.0 2.9e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Beta2-adaptin appendage, C-terminal sub-domain FHA PF00498.26 KDO29894.1 - 7.3e-18 64.7 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO29894.1 - 4.3e-08 33.4 0.0 7.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Calx-beta PF03160.14 KDO29895.1 - 1.1e-28 99.3 15.4 3.3e-09 36.8 0.1 10.1 10 0 0 10 10 10 7 Calx-beta domain stn_TNFRSF12A PF12191.8 KDO29897.1 - 0.023 14.9 0.6 0.045 14.0 0.6 1.5 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Alpha_GJ PF03229.13 KDO29897.1 - 0.031 14.8 10.3 0.048 14.2 10.3 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Collectrin PF16959.5 KDO29897.1 - 0.11 12.3 1.1 0.17 11.7 1.0 1.4 1 1 0 1 1 1 0 Renal amino acid transporter EphA2_TM PF14575.6 KDO29897.1 - 0.12 13.3 0.7 1.8 9.5 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Myelin_PLP PF01275.19 KDO29897.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) MGC-24 PF05283.11 KDO29897.1 - 0.22 12.0 4.5 0.37 11.2 4.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin T4SS_CagC PF16943.5 KDO29897.1 - 0.39 10.9 7.4 0.072 13.3 2.8 1.9 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system DUF983 PF06170.12 KDO29897.1 - 0.52 10.8 4.0 0.52 10.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) CxC6 PF18721.1 KDO29898.1 - 7 7.0 13.7 0.35 11.2 5.2 3.0 2 1 1 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases SIS PF01380.22 KDO29899.1 - 7.8e-33 113.1 0.2 1e-15 57.8 0.0 3.1 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 KDO29899.1 - 1.8e-23 83.2 0.2 5.2e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KDO29899.1 - 1.2e-18 67.2 0.0 2.1e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KDO29899.1 - 0.00017 20.6 0.1 0.00038 19.4 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF3630 PF12305.8 KDO29900.1 - 0.046 13.8 0.5 0.097 12.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) Cauli_AT PF03233.13 KDO29900.1 - 0.28 11.1 3.9 0.47 10.4 0.6 2.4 1 1 1 2 2 2 0 Aphid transmission protein AAA_13 PF13166.6 KDO29900.1 - 2.8 6.5 14.5 10 4.6 14.6 1.7 1 1 0 1 1 1 0 AAA domain DUF4200 PF13863.6 KDO29900.1 - 2.8 8.4 18.6 23 5.4 3.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 KDO29900.1 - 3.7 7.8 16.8 0.88 9.8 9.4 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Apt1 PF10351.9 KDO29900.1 - 4.5 6.0 8.7 6.8 5.4 8.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rx_N PF18052.1 KDO29900.1 - 5.6 7.3 12.4 0.098 12.9 4.1 2.3 3 0 0 3 3 3 0 Rx N-terminal domain HAUS6_N PF14661.6 KDO29900.1 - 8.1 5.9 16.6 0.71 9.4 8.6 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3584 PF12128.8 KDO29900.1 - 9.5 3.6 23.0 0.99 6.8 14.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ubiquitin PF00240.23 KDO29901.1 - 0.00022 20.9 0.0 0.00047 19.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family SHIPPO-rpt PF07004.12 KDO29901.1 - 0.02 15.8 2.0 0.02 15.8 2.0 2.8 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat Rad60-SLD PF11976.8 KDO29901.1 - 0.095 12.5 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ank_2 PF12796.7 KDO29902.1 - 7.6e-25 87.3 3.2 2.1e-14 53.9 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KDO29902.1 - 2.7e-20 71.8 4.0 1.1e-05 25.6 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KDO29902.1 - 1.4e-17 62.0 1.2 0.00049 20.3 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO29902.1 - 3.7e-16 59.0 5.8 6.5e-09 35.9 0.5 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29902.1 - 4.4e-15 55.8 4.5 1.3e-10 41.6 0.1 4.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) WW PF00397.26 KDO29902.1 - 1.2e-12 47.7 15.2 0.00015 21.7 0.3 4.7 4 0 0 4 4 4 4 WW domain EF-hand_8 PF13833.6 KDO29902.1 - 1.1e-09 37.9 0.2 0.00044 20.0 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KDO29902.1 - 1.4e-08 35.0 0.1 3.7e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO29902.1 - 2.9e-07 29.6 0.0 0.00065 19.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KDO29902.1 - 1.6e-05 24.2 0.0 0.00066 19.1 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO29902.1 - 6.2e-05 22.6 0.0 0.023 14.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Herpes_UL56 PF04534.12 KDO29902.1 - 0.0023 17.5 0.5 0.0063 16.0 0.5 1.7 1 0 0 1 1 1 1 Herpesvirus UL56 protein EF-hand_10 PF14788.6 KDO29902.1 - 0.035 14.0 0.0 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 EF hand DUF987 PF06174.11 KDO29902.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF987) DUF5133 PF17196.4 KDO29902.1 - 0.15 12.3 4.5 0.74 10.1 0.6 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) Elf1 PF05129.13 KDO29904.1 - 8.1e-30 102.7 5.8 9.1e-30 102.5 5.8 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 KDO29904.1 - 0.22 11.6 3.9 0.35 11.0 0.3 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger C1_4 PF07975.12 KDO29904.1 - 0.41 10.9 6.1 0.2 11.9 0.7 2.2 2 1 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 KDO29904.1 - 0.44 11.5 5.3 8.9 7.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PPR_2 PF13041.6 KDO29905.1 - 4.8e-27 93.9 7.7 0.0075 16.5 0.0 11.3 10 2 3 13 13 13 5 PPR repeat family PPR_3 PF13812.6 KDO29905.1 - 1.2e-19 70.2 0.1 0.004 17.2 0.0 7.8 7 1 1 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.20 KDO29905.1 - 2.9e-16 58.5 12.8 0.37 11.1 0.0 13.0 14 0 0 14 14 14 5 PPR repeat PPR_long PF17177.4 KDO29905.1 - 4.6e-14 52.3 14.3 2.2e-05 23.9 0.3 7.3 3 2 6 9 9 9 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KDO29905.1 - 4.4e-06 27.1 3.1 0.3 11.6 0.0 6.6 7 1 1 8 8 8 1 Tetratricopeptide repeat PPR_1 PF12854.7 KDO29905.1 - 0.00052 19.7 6.7 0.54 10.0 0.0 6.0 7 0 0 7 7 7 1 PPR repeat TPR_6 PF13174.6 KDO29905.1 - 0.01 16.4 0.5 78 4.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29905.1 - 0.014 16.2 13.7 2.1 9.4 0.0 7.9 10 0 0 10 10 10 0 Tetratricopeptide repeat PhageMin_Tail PF10145.9 KDO29905.1 - 0.021 14.7 0.2 0.73 9.7 0.0 3.0 3 1 0 3 3 3 0 Phage-related minor tail protein DUF627 PF04781.12 KDO29905.1 - 0.1 12.6 0.2 4.6 7.3 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF627) Glyoxalase PF00903.25 KDO29906.1 - 5.4e-05 23.4 0.1 0.00014 22.0 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KDO29906.1 - 0.0084 16.2 0.1 0.043 13.9 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KDO29906.1 - 0.025 14.9 0.2 0.19 12.0 0.2 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DNA_pol_A_exo1 PF01612.20 KDO29907.1 - 8.6e-20 71.2 0.3 1.1e-19 70.8 0.3 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_2 PF12756.7 KDO29907.1 - 0.018 15.4 0.8 5.6 7.4 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KDO29907.1 - 0.13 12.8 2.7 2.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 KDO29907.1 - 0.32 11.1 1.9 28 4.9 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KDO29907.1 - 0.5 10.4 2.6 0.87 9.7 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KDO29907.1 - 0.82 9.6 4.4 2 8.4 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 KDO29907.1 - 1.1 10.2 5.5 12 7.1 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 KDO29907.1 - 1.2 9.4 4.2 5.5 7.2 0.2 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf_C2H2_ZHX PF18387.1 KDO29907.1 - 2.6 7.8 5.2 1.8 8.2 0.1 2.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KDO29908.1 - 9.4e-09 35.3 25.7 0.003 17.9 1.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KDO29908.1 - 9.1e-06 25.8 5.7 0.26 11.6 0.0 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KDO29908.1 - 1.3e-05 25.6 30.1 0.0045 17.7 1.9 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KDO29908.1 - 1.7e-05 25.0 9.1 0.025 15.0 0.1 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KDO29908.1 - 6.4e-05 22.6 20.5 0.034 13.9 0.1 4.4 4 0 0 4 4 4 3 zinc-finger C2H2-type DNA_pol_A_exo1 PF01612.20 KDO29908.1 - 0.00069 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_6 PF13912.6 KDO29908.1 - 0.0055 16.7 2.7 0.0055 16.7 2.7 4.1 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KDO29908.1 - 0.056 13.4 9.9 1.8 8.5 0.3 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Focal_AT PF03623.13 KDO29908.1 - 0.11 12.5 1.0 0.23 11.4 1.0 1.6 1 0 0 1 1 1 0 Focal adhesion targeting region zf-C2H2_8 PF15909.5 KDO29908.1 - 0.12 12.7 13.4 2.2 8.6 4.3 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon Herpes_BLLF1 PF05109.13 KDO29908.1 - 4.7 5.1 25.1 6.8 4.5 25.1 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Elicitin PF00964.17 KDO29909.1 - 0.00016 21.7 1.9 0.00016 21.7 1.9 1.6 1 1 1 2 2 2 1 Elicitin MGC-24 PF05283.11 KDO29909.1 - 0.25 11.8 10.4 0.035 14.6 5.2 1.9 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyoxalase PF00903.25 KDO29912.1 - 0.0001 22.5 0.1 0.00079 19.6 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KDO29912.1 - 0.036 14.3 0.0 0.052 13.8 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3626 PF12294.8 KDO29912.1 - 0.054 12.5 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Metallophos PF00149.28 KDO29913.1 - 4.2e-17 63.3 0.0 6.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KDO29913.1 - 1.8e-15 57.3 0.0 8.2e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KDO29913.1 - 3.1e-14 53.6 0.2 6.5e-14 52.5 0.2 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3_PAP PF17808.1 KDO29913.1 - 0.073 13.2 0.2 0.55 10.4 0.1 2.3 2 1 1 3 3 3 0 Fn3-like domain from Purple Acid Phosphatase Nop53 PF07767.11 KDO29916.1 - 0.003 17.0 25.6 0.0043 16.5 25.6 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KDO29916.1 - 0.021 13.2 27.4 0.026 12.9 27.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KDO29916.1 - 0.22 10.8 26.2 0.27 10.5 26.2 1.2 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 KDO29916.1 - 1.2 9.0 31.5 1.9 8.5 27.4 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Pes-10 PF07149.11 KDO29916.1 - 2.1 7.3 19.9 3.3 6.7 19.9 1.3 1 0 0 1 1 1 0 Pes-10 Sporozoite_P67 PF05642.11 KDO29916.1 - 2.2 6.2 8.0 3 5.8 8.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFAP1 PF06991.11 KDO29916.1 - 4.1 7.2 35.5 8.7 6.1 35.5 1.7 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing YL1 PF05764.13 KDO29916.1 - 5 7.2 44.4 2.1 8.4 41.6 1.7 1 1 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 KDO29916.1 - 7 6.3 47.8 3.2 7.4 43.5 2.0 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KDO29916.1 - 7.7 7.0 28.8 20 5.7 28.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ig_mannosidase PF17753.1 KDO29917.1 - 1.6e-10 40.6 0.2 4.6e-10 39.1 0.2 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KDO29917.1 - 0.19 12.4 2.5 0.2 12.3 0.7 2.0 2 0 0 2 2 2 0 Mannosidase Ig/CBM-like domain IP_trans PF02121.18 KDO29918.1 - 4.5 6.8 7.3 1.2 8.6 4.1 1.6 1 1 0 1 1 1 0 Phosphatidylinositol transfer protein LNS2 PF08235.13 KDO29918.1 - 6.9 6.1 9.5 14 5.1 0.5 3.0 3 0 0 3 3 3 0 LNS2 (Lipin/Ned1/Smp2) PT PF04886.12 KDO29920.1 - 1.9e-12 46.5 53.0 0.019 14.5 45.3 3.5 2 1 0 2 2 2 1 PT repeat Macoilin PF09726.9 KDO29920.1 - 0.15 10.6 2.4 0.16 10.5 2.4 1.0 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 KDO29920.1 - 2.3 7.4 5.3 2.6 7.2 5.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.12 KDO29920.1 - 2.3 6.1 4.1 2.6 5.9 4.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PT PF04886.12 KDO29921.1 - 8e-09 34.9 47.4 3.2e-07 29.8 18.1 3.4 2 1 1 3 3 3 2 PT repeat Macoilin PF09726.9 KDO29921.1 - 0.23 10.0 2.9 0.26 9.8 2.9 1.0 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 KDO29921.1 - 5.5 6.1 6.2 6.6 5.8 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ank PF00023.30 KDO29922.1 - 3.2e-17 62.1 0.3 1.2e-08 35.0 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KDO29922.1 - 3.6e-16 59.3 0.4 5.5e-06 26.8 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO29922.1 - 8e-16 58.4 0.0 1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO29922.1 - 2.5e-13 48.9 0.0 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO29922.1 - 4.8e-10 39.5 0.2 7.9e-08 32.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PEGA PF08308.11 KDO29922.1 - 0.11 12.4 0.1 0.42 10.5 0.1 1.9 2 1 0 2 2 2 0 PEGA domain EXS PF03124.14 KDO29923.1 - 4.8e-12 45.8 1.6 5.9e-12 45.5 1.1 1.4 2 0 0 2 2 2 1 EXS family EXS PF03124.14 KDO29924.1 - 4.4e-43 147.9 18.7 1.3e-40 139.7 7.2 2.9 3 1 1 4 4 4 2 EXS family SPX PF03105.19 KDO29924.1 - 3.5e-12 47.0 5.5 9.5e-06 25.8 2.4 2.8 1 1 2 3 3 3 2 SPX domain BT1 PF03092.16 KDO29925.1 - 2.1e-15 56.0 20.1 5e-11 41.5 1.4 3.4 2 1 1 3 3 3 3 BT1 family ATP_bind_3 PF01171.20 KDO29926.1 - 6.2e-38 130.4 0.0 9.5e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 KDO29926.1 - 7.8e-23 81.5 1.2 1.6e-22 80.5 1.2 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) QueC PF06508.13 KDO29926.1 - 3.1e-05 23.6 0.0 0.0073 15.8 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KDO29926.1 - 7.1e-05 22.6 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 KDO29926.1 - 0.00019 20.7 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 KDO29926.1 - 0.00045 19.1 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KDO29926.1 - 0.0092 15.6 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KDO29926.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family RPA_interact_N PF14766.6 KDO29926.1 - 0.077 12.6 0.8 0.21 11.2 0.8 1.8 1 0 0 1 1 1 0 Replication protein A interacting N-terminal RNA_pol_Rpb5_C PF01191.19 KDO29927.1 - 1.5e-32 111.3 0.5 2.8e-32 110.4 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KDO29927.1 - 2.2e-28 98.7 0.0 3.5e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KDO29927.1 - 0.0093 16.0 0.0 0.033 14.2 0.0 2.0 2 1 0 2 2 2 1 Restriction endonuclease BamHI PF02923.15 KDO29927.1 - 0.072 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BamHI Agenet PF05641.12 KDO29928.1 - 1.7e-16 60.4 5.1 0.012 16.1 0.0 5.4 5 0 0 5 5 5 4 Agenet domain LBR_tudor PF09465.10 KDO29928.1 - 5.6e-12 45.3 4.1 0.0039 17.0 0.1 4.1 4 0 0 4 4 4 3 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 KDO29928.1 - 1.4e-07 31.1 7.9 0.00087 18.9 0.3 4.2 5 0 0 5 5 5 3 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 KDO29928.1 - 6.7e-07 29.1 4.0 1 9.3 0.0 5.3 5 0 0 5 5 5 3 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KDO29928.1 - 2.6e-06 27.5 0.5 0.074 13.1 0.0 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KDO29928.1 - 4.9e-05 23.4 0.0 2.1 8.4 0.0 3.9 2 1 2 4 4 4 1 SGF29 tudor-like domain 53-BP1_Tudor PF09038.10 KDO29928.1 - 0.00027 20.9 4.3 0.13 12.2 0.2 3.6 3 1 1 4 4 4 2 Tumour suppressor p53-binding protein-1 Tudor TUDOR PF00567.24 KDO29928.1 - 0.00059 19.9 0.2 0.47 10.5 0.0 3.5 2 1 2 4 4 4 1 Tudor domain CDC45 PF02724.14 KDO29928.1 - 0.087 11.1 0.8 0.11 10.8 0.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TTD PF12148.8 KDO29928.1 - 0.091 12.6 1.4 2.3 8.1 0.0 3.3 2 1 0 2 2 2 0 Tandem tudor domain within UHRF1 SH3_15 PF18346.1 KDO29928.1 - 1.1 9.7 9.5 30 5.0 0.1 4.8 3 2 0 3 3 3 0 Mind bomb SH3 repeat domain Pinin_SDK_N PF04697.13 KDO29928.1 - 2.7 8.6 12.5 0.24 12.0 4.3 2.7 3 0 0 3 3 2 0 pinin/SDK conserved region Cupin_8 PF13621.6 KDO29929.1 - 1.6e-37 129.6 0.0 2.2e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KDO29929.1 - 9.2e-13 48.3 0.1 1.7e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KDO29929.1 - 0.00032 21.1 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase NYD-SP28_assoc PF14775.6 KDO29933.1 - 0.048 13.8 5.2 0.68 10.1 0.6 4.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain PKcGMP_CC PF16808.5 KDO29933.1 - 0.24 11.3 10.8 12 5.8 0.0 6.8 5 1 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase USP8_dimer PF08969.11 KDO29933.1 - 0.31 11.2 3.0 0.63 10.2 0.1 3.3 2 0 0 2 2 2 0 USP8 dimerisation domain EMP24_GP25L PF01105.24 KDO29933.1 - 3.7 7.5 0.0 3.7 7.5 0.0 6.8 3 3 1 5 5 5 0 emp24/gp25L/p24 family/GOLD Glyco_trans_2_3 PF13632.6 KDO29934.1 - 5.2e-18 65.7 0.7 1e-16 61.4 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 KDO29934.1 - 2.8e-14 52.6 8.1 2.1e-10 39.8 0.3 3.6 3 1 1 4 4 4 2 Cellulose synthase PH PF00169.29 KDO29934.1 - 2.2e-09 37.8 0.1 8.1e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 PH domain Glycos_transf_2 PF00535.26 KDO29934.1 - 3.1e-08 33.6 0.0 0.16 11.8 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KDO29934.1 - 3.7e-08 33.5 0.0 0.0012 18.8 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KDO29934.1 - 5.4e-05 22.7 0.0 0.0031 17.0 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 21 PH_11 PF15413.6 KDO29934.1 - 0.0013 19.1 0.1 0.0031 17.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 KDO29934.1 - 0.0035 17.6 11.6 0.0035 17.6 11.6 3.0 3 0 0 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding PH_8 PF15409.6 KDO29934.1 - 0.007 16.6 0.4 0.13 12.6 0.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pribosyltran_N PF13793.6 KDO29935.1 - 2.1e-35 121.2 1.2 8.9e-35 119.1 0.1 2.2 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KDO29935.1 - 1.9e-25 89.9 0.5 1.9e-25 89.9 0.5 1.7 2 1 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KDO29935.1 - 3.7e-14 52.5 1.0 1e-12 47.8 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KDO29935.1 - 0.017 14.6 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TBP PF00352.21 KDO29936.1 - 2.8e-39 132.9 0.0 1.3e-21 76.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KDO29936.1 - 0.015 15.4 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) Ank_4 PF13637.6 KDO29937.1 - 5.9e-27 93.7 3.3 1.9e-09 37.8 0.1 4.9 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO29937.1 - 5e-21 75.1 9.8 1.4e-09 38.4 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO29937.1 - 1.3e-19 70.0 9.1 6.4e-06 26.3 0.5 6.0 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29937.1 - 4.9e-16 57.2 6.0 0.013 16.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KDO29937.1 - 1.8e-14 53.4 14.1 5.2e-05 23.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat TPR_2 PF07719.17 KDO29938.1 - 3.2e-08 33.1 12.4 0.0015 18.5 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO29938.1 - 6.8e-06 26.3 16.0 0.00029 21.0 5.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO29938.1 - 1.7e-05 24.4 3.1 0.0053 16.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO29938.1 - 0.00012 22.6 12.3 0.2 12.5 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO29938.1 - 0.00057 19.7 0.1 0.00057 19.7 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO29938.1 - 0.00059 19.8 3.7 0.21 11.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 KDO29938.1 - 0.009 15.5 0.1 0.009 15.5 0.1 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KDO29938.1 - 0.012 16.2 8.1 0.58 10.9 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO29938.1 - 0.091 13.4 0.0 0.091 13.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO29938.1 - 0.35 10.8 0.0 0.35 10.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO29939.1 - 3.4e-68 229.9 0.0 4.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29939.1 - 3.3e-37 128.2 0.0 4.2e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO29939.1 - 2.6e-09 36.8 0.0 4.4e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO29939.1 - 9.3e-06 25.1 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO29939.1 - 0.0015 18.5 2.2 0.013 15.5 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KDO29939.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KDO29939.1 - 0.0094 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KDO29939.1 - 0.03 13.9 0.2 0.053 13.1 0.2 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase PKD_channel PF08016.12 KDO29940.1 - 1.2e-14 53.8 21.8 3e-13 49.3 19.1 2.9 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KDO29940.1 - 4.4e-11 42.5 15.3 7.8e-11 41.7 15.3 1.4 1 0 0 1 1 1 1 Ion transport protein SlyX PF04102.12 KDO29940.1 - 0.02 15.5 0.1 0.057 14.0 0.1 1.8 1 0 0 1 1 1 0 SlyX RuBisCO_large_N PF02788.16 KDO29940.1 - 0.13 12.4 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain CLZ PF16526.5 KDO29940.1 - 0.14 12.5 0.3 0.4 11.1 0.3 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dynamitin PF04912.14 KDO29942.1 - 3.3e-55 188.0 17.7 1.2e-53 182.9 17.7 2.0 1 1 0 1 1 1 1 Dynamitin AOX PF01786.17 KDO29942.1 - 0.0067 16.0 1.7 0.17 11.4 1.7 2.2 1 1 0 1 1 1 1 Alternative oxidase Sugarporin_N PF11471.8 KDO29942.1 - 0.012 15.6 0.7 0.064 13.2 0.0 2.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF2730 PF10805.8 KDO29942.1 - 0.13 12.4 7.8 2.4 8.3 0.9 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) Bacillus_HBL PF05791.11 KDO29942.1 - 1.6 8.6 8.7 1 9.2 2.3 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) PspB PF06667.12 KDO29942.1 - 1.8 8.7 5.3 2.2 8.4 0.1 3.3 2 1 1 3 3 3 0 Phage shock protein B DASH_Dam1 PF08653.10 KDO29942.1 - 6.5 6.6 11.4 8.3 6.3 0.3 4.7 5 2 2 7 7 7 0 DASH complex subunit Dam1 WD40 PF00400.32 KDO29943.1 - 2.7e-16 59.6 4.5 7.6e-06 26.6 0.6 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO29943.1 - 1.9e-08 34.5 1.4 0.0095 16.2 0.2 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO29943.1 - 3.9e-05 22.8 0.0 0.78 8.6 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_A_exoN PF18305.1 KDO29943.1 - 0.17 12.2 3.4 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain Pkinase PF00069.25 KDO29944.1 - 7e-21 74.8 0.0 9e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29944.1 - 2.6e-13 49.9 0.1 3.9e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO29944.1 - 0.00015 21.7 1.5 0.002 18.1 1.5 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO29944.1 - 0.0028 16.5 0.0 0.0031 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase SpoU_methylase PF00588.19 KDO29946.1 - 5.5e-26 91.4 0.0 1.2e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF5578 PF17741.1 KDO29946.1 - 0.015 14.8 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5578) Motile_Sperm PF00635.26 KDO29947.1 - 3.9e-08 33.1 0.0 5.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Usp PF00582.26 KDO29948.1 - 1.1e-09 39.0 1.0 0.00061 20.3 0.5 2.9 2 1 0 2 2 2 2 Universal stress protein family Nuc_sug_transp PF04142.15 KDO29949.1 - 1.7e-71 241.0 23.6 2e-71 240.7 23.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KDO29949.1 - 2.3e-05 23.8 20.3 0.00013 21.3 20.2 2.1 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KDO29949.1 - 0.00014 21.2 11.5 0.00014 21.2 11.5 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 KDO29949.1 - 0.0068 15.8 10.3 0.0068 15.8 10.3 3.0 1 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.20 KDO29949.1 - 0.088 13.0 31.8 0.5 10.5 14.8 3.8 2 2 0 2 2 2 0 EamA-like transporter family Wzz PF02706.15 KDO29949.1 - 0.73 10.2 0.1 0.73 10.2 0.1 3.1 3 0 0 3 3 3 0 Chain length determinant protein MTABC_N PF16185.5 KDO29949.1 - 4.2 6.8 11.5 19 4.7 11.0 2.2 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Pkinase PF00069.25 KDO29950.1 - 3.1e-71 239.8 0.0 4.8e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO29950.1 - 2.6e-32 112.1 0.0 4.1e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KDO29950.1 - 3.6e-15 55.9 0.2 1.4e-14 54.0 0.1 2.0 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 KDO29950.1 - 2.1e-07 30.6 0.0 7.3e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KDO29950.1 - 0.0025 18.5 0.9 0.011 16.5 0.4 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 KDO29950.1 - 0.0041 16.8 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KDO29950.1 - 0.015 15.2 0.0 0.081 12.8 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KDO29950.1 - 0.06 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pro_dh PF01619.18 KDO29951.1 - 3.4e-80 269.7 1.3 1.2e-79 267.9 1.3 1.7 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_8 PF13833.6 KDO29951.1 - 3.3e-05 23.6 0.0 0.00014 21.7 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KDO29951.1 - 0.00015 22.1 0.0 0.001 19.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO29951.1 - 0.0051 16.3 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 EF hand FliG_N PF14842.6 KDO29951.1 - 0.014 16.0 0.1 0.93 10.1 0.1 2.6 2 0 0 2 2 2 0 FliG N-terminal domain EF-hand_6 PF13405.6 KDO29951.1 - 0.019 14.8 0.0 0.082 12.9 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain PTEN_C2 PF10409.9 KDO29952.1 - 1e-10 41.5 0.1 1.7e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KDO29952.1 - 4.4e-07 29.8 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KDO29952.1 - 4.5e-05 23.5 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO29952.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L35p PF01632.19 KDO29953.1 - 2.7e-16 59.8 7.5 3.4e-16 59.5 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 TRP PF06011.12 KDO29955.1 - 4.6e-19 68.4 21.1 1.2e-16 60.5 21.1 2.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Adaptin_N PF01602.20 KDO29956.1 - 4.2e-79 266.5 5.8 6.3e-79 265.9 5.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KDO29956.1 - 3.5e-57 191.9 0.0 8.2e-57 190.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KDO29956.1 - 1.3e-47 161.2 0.0 2.6e-47 160.3 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 KDO29956.1 - 2.7e-07 30.8 3.1 2e-06 27.9 0.2 3.0 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KDO29956.1 - 2.4e-06 27.8 9.5 0.0095 16.3 0.1 6.0 2 1 3 6 6 6 2 HEAT repeats Coatomer_g_Cpla PF16381.5 KDO29956.1 - 0.00029 21.0 0.0 0.0008 19.5 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KDO29956.1 - 0.0033 17.5 0.6 4.6 7.8 0.1 4.1 4 0 0 4 4 4 1 HEAT repeat HSR PF03172.13 KDO29956.1 - 0.15 12.2 0.2 29 4.9 0.0 3.1 3 0 0 3 3 3 0 HSR domain Ank_2 PF12796.7 KDO29957.1 - 1e-24 86.9 24.6 3.6e-06 27.5 0.2 6.1 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO29957.1 - 6.4e-22 77.3 33.0 0.0011 19.3 0.1 12.0 2 2 8 12 12 12 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO29957.1 - 1.2e-21 76.7 23.7 4.7e-05 23.9 0.2 9.9 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO29957.1 - 8e-09 35.0 22.0 6.8 7.6 0.0 12.1 13 1 1 14 14 14 4 Ankyrin repeat DUF1707 PF08044.11 KDO29957.1 - 0.16 12.0 5.2 23 5.2 0.1 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) Homez PF11569.8 KDO29957.1 - 0.17 11.4 0.2 9 5.8 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Ribosomal_S17_N PF16205.5 KDO29959.1 - 7.4e-32 109.5 0.7 7.4e-32 109.5 0.7 1.8 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KDO29959.1 - 3.3e-27 94.4 3.0 3.3e-27 94.4 3.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 G-patch PF01585.23 KDO29960.1 - 2e-15 56.4 1.7 4.4e-15 55.3 1.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KDO29960.1 - 4.9e-05 23.3 0.6 4.9e-05 23.3 0.6 3.0 3 0 0 3 3 3 1 G-patch domain LZ_Tnp_IS66 PF13007.7 KDO29960.1 - 0.93 10.3 7.2 10 7.0 2.0 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain SPT6_acidic PF14632.6 KDO29960.1 - 2.2 8.9 21.4 0.45 11.1 2.5 2.6 3 0 0 3 3 3 0 Acidic N-terminal SPT6 DUF3501 PF12007.8 KDO29961.1 - 0.042 13.8 0.1 1.8 8.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3501) RNA_pol PF00940.19 KDO29962.1 - 2.5e-62 211.1 0.0 4.1e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KDO29962.1 - 4.5e-55 187.4 0.0 6.3e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal CRAL_TRIO PF00650.20 KDO29963.1 - 9.6e-17 61.2 0.2 1.6e-16 60.5 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PX PF00787.24 KDO29963.1 - 1.9e-10 40.7 0.0 6e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 PX domain CRAL_TRIO_2 PF13716.6 KDO29963.1 - 0.00039 20.6 2.0 0.00046 20.4 0.8 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Whirly PF08536.11 KDO29965.1 - 1.5e-15 57.2 0.0 2.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Whirly transcription factor NADH-u_ox-rdase PF10785.9 KDO29966.1 - 2e-10 41.2 0.0 2.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH-u_ox-rdase PF10785.9 KDO29967.1 - 1.1e-19 70.9 0.2 1.2e-19 70.7 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Abhydrolase_6 PF12697.7 KDO29968.1 - 1.1e-05 26.2 3.4 1.1e-05 26.2 3.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KDO29968.1 - 0.0017 17.9 0.1 0.0088 15.6 0.1 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KDO29968.1 - 0.0024 17.6 0.4 0.0045 16.7 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KDO29968.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 KDO29968.1 - 0.055 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KDO29968.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase WAPL PF07814.13 KDO29969.1 - 0.0019 17.0 0.4 0.0036 16.2 0.4 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF4704 PF15787.5 KDO29969.1 - 0.034 13.4 0.1 0.063 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) SHQ1 PF04925.15 KDO29969.1 - 0.21 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein zf-AN1 PF01428.16 KDO29970.1 - 8.4e-11 41.9 6.8 1.3e-10 41.2 6.8 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger zf-C5HC2 PF02928.16 KDO29970.1 - 0.0085 16.5 5.4 0.013 15.9 5.4 1.3 1 0 0 1 1 1 1 C5HC2 zinc finger UPF0547 PF10571.9 KDO29970.1 - 0.011 15.8 4.2 0.023 14.7 4.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 IBR PF01485.21 KDO29970.1 - 0.4 10.9 9.8 1.3 9.3 9.8 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Med3 PF11593.8 KDO29970.1 - 3.4 6.8 6.8 4 6.5 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal cobW PF02492.19 KDO29971.1 - 1.2e-33 116.2 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KDO29971.1 - 0.00021 20.3 0.9 0.00069 18.7 0.9 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KDO29971.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO29971.1 - 0.048 14.2 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO29971.1 - 0.051 14.0 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KDO29971.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KDO29971.1 - 0.19 12.2 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Spt5_N PF11942.8 KDO29971.1 - 0.28 12.2 5.1 0.53 11.3 5.1 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Zip PF02535.22 KDO29971.1 - 0.39 9.9 8.6 0.49 9.6 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CASP_C PF08172.12 KDO29972.1 - 0.24 10.7 1.2 0.31 10.3 1.2 1.2 1 0 0 1 1 1 0 CASP C terminal UQ_con PF00179.26 KDO29974.1 - 2e-50 170.1 0.0 2.3e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KDO29974.1 - 0.0044 16.7 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KDO29974.1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KDO29974.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Dor1 PF04124.12 KDO29975.1 - 2.2e-45 154.9 0.4 3.1e-45 154.3 0.4 1.2 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.13 KDO29975.1 - 0.00056 18.6 1.2 0.00098 17.8 1.2 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.6 KDO29975.1 - 0.061 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 HSCB_C PF07743.13 KDO29975.1 - 7.9 7.1 6.7 93 3.6 4.1 3.3 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Myotub-related PF06602.14 KDO29977.1 - 2.7e-109 365.3 0.0 4.2e-109 364.7 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 KDO29977.1 - 3.4e-10 39.9 6.5 7.4e-10 38.8 6.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 KDO29977.1 - 0.0086 16.0 0.8 0.023 14.6 0.8 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Y_phosphatase PF00102.27 KDO29977.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-RING_5 PF14634.6 KDO29977.1 - 0.025 14.5 10.4 0.048 13.6 10.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FYVE_2 PF02318.16 KDO29977.1 - 0.033 14.4 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 KDO29977.1 - 0.062 13.2 7.2 0.14 12.1 7.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KDO29977.1 - 0.25 11.4 6.0 0.59 10.2 6.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO29977.1 - 0.39 10.6 4.9 1.2 9.0 4.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO29977.1 - 1.7 9.0 9.4 4.2 7.8 9.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KDO29977.1 - 1.9 8.4 9.5 17 5.4 9.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KDO29977.1 - 2.3 8.5 8.3 6.4 7.1 8.3 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PLATZ PF04640.14 KDO29978.1 - 0.00099 19.7 0.2 0.0016 19.0 0.2 1.4 1 0 0 1 1 1 1 PLATZ transcription factor ODR4-like PF14778.6 KDO29979.1 - 8.6e-22 77.6 0.0 4.7e-14 52.1 0.0 2.2 1 1 1 2 2 2 2 Olfactory receptor 4-like Cytochrom_B_N_2 PF13631.6 KDO29979.1 - 0.036 14.1 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SpoIIE PF07228.12 KDO29982.1 - 2.2e-08 34.3 0.1 4.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KDO29982.1 - 2.4e-06 27.3 0.1 3.8e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KDO29982.1 - 0.0047 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C UreF PF01730.16 KDO29983.1 - 1.5e-22 80.6 2.5 1.9e-22 80.3 2.5 1.1 1 0 0 1 1 1 1 UreF Myb_Cef PF11831.8 KDO29985.1 - 4.9e-30 104.9 8.7 4.9e-30 104.9 8.7 3.9 3 2 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KDO29985.1 - 2e-21 75.9 6.4 1.8e-11 44.1 1.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO29985.1 - 1.2e-19 70.3 7.2 7.6e-13 48.5 3.4 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rhabdo_matrix PF03397.14 KDO29985.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus matrix protein C2 PF00168.30 KDO29986.1 - 4.9e-09 36.4 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Exo_endo_phos PF03372.23 KDO29986.1 - 4.2e-07 29.7 0.0 7.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KDO29987.1 - 5e-16 58.2 8.9 6e-10 38.7 1.5 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO29987.1 - 2.1e-12 47.1 5.4 1.8e-06 28.2 2.7 3.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) NRDE-2 PF08424.10 KDO29987.1 - 1.6e-07 30.8 0.1 3.8e-07 29.5 0.1 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference zf-C3H1 PF10650.9 KDO29987.1 - 5.2e-07 29.3 5.7 1.1e-06 28.2 5.7 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain LRR_6 PF13516.6 KDO29987.1 - 0.0061 16.5 12.4 2.1 8.6 0.4 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 KDO29987.1 - 0.11 13.1 14.6 33 5.6 0.4 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 KDO29987.1 - 0.25 10.8 0.3 0.5 9.8 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Pox_A_type_inc PF04508.12 KDO29988.1 - 0.26 11.2 5.3 1.5 8.8 2.8 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Hamartin PF04388.12 KDO29988.1 - 0.89 8.1 8.3 1.1 7.9 8.3 1.1 1 0 0 1 1 1 0 Hamartin protein CRAL_TRIO PF00650.20 KDO29989.1 - 2.6e-32 111.7 0.0 3.6e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 KDO29989.1 - 0.0017 18.8 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 KDO29989.1 - 0.2 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ThiF PF00899.21 KDO29990.1 - 5.3e-60 202.8 0.0 7.4e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KDO29990.1 - 1.3e-11 44.9 0.0 2.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 KDO29990.1 - 0.37 10.9 1.1 0.66 10.0 0.1 1.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ubiquitin PF00240.23 KDO29991.1 - 8.2e-33 112.0 0.4 1.4e-32 111.2 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO29991.1 - 1.4e-14 53.7 0.7 2.4e-14 52.9 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PHD PF00628.29 KDO29991.1 - 3.2e-08 33.3 3.7 6.2e-08 32.4 3.7 1.4 1 0 0 1 1 1 1 PHD-finger Ubiquitin_2 PF14560.6 KDO29991.1 - 0.00037 20.9 0.1 0.0014 19.0 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain FANCL_C PF11793.8 KDO29991.1 - 0.028 14.6 0.8 0.051 13.8 0.8 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KDO29991.1 - 0.035 14.0 0.9 0.088 12.8 0.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TBK1_ULD PF18396.1 KDO29991.1 - 0.066 13.2 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KDO29991.1 - 0.091 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO29991.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-RING_2 PF13639.6 KDO29991.1 - 0.14 12.5 5.5 0.23 11.8 5.5 1.3 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 KDO29991.1 - 2.3 8.4 4.1 6.1 7.0 4.1 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger GAF PF01590.26 KDO29992.1 - 0.00039 21.1 0.0 0.0012 19.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO29992.1 - 0.00053 20.3 0.0 0.0035 17.7 0.0 2.3 3 0 0 3 3 3 1 GAF domain zf-CCHC_5 PF14787.6 KDO29993.1 - 0.0071 16.0 0.3 0.0071 16.0 0.3 1.8 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger DUF4211 PF13926.6 KDO29993.1 - 0.071 13.2 0.1 0.092 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) cNMP_binding PF00027.29 KDO29994.1 - 7.2e-14 51.6 0.1 1.6e-06 28.1 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain MIS13 PF08202.11 KDO29994.1 - 0.14 11.4 0.1 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Mis12-Mtw1 protein family Kri1_C PF12936.7 KDO29995.1 - 2.3e-25 88.6 3.6 2.3e-25 88.6 3.6 4.7 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 KDO29995.1 - 6.7e-23 81.2 4.7 6.7e-23 81.2 4.7 6.9 3 3 2 6 6 6 1 KRI1-like family NPV_P10 PF05531.12 KDO29996.1 - 0.0035 17.8 0.1 0.0063 16.9 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF5423 PF17461.2 KDO29996.1 - 0.016 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DUF659 PF04937.15 KDO29996.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Myb_DNA-binding PF00249.31 KDO29998.1 - 8.9e-12 45.0 0.4 1.4e-11 44.3 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO29998.1 - 0.00056 20.1 0.1 0.0011 19.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO29998.1 - 0.001 18.9 0.4 0.0022 17.8 0.4 1.5 1 0 0 1 1 1 1 Myb DNA-binding like CEND1 PF15677.5 KDO29998.1 - 2.1 8.9 10.0 0.82 10.2 4.6 2.3 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 UAA PF08449.11 KDO29999.1 - 7.1e-53 179.8 13.6 8.5e-53 179.5 13.6 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KDO29999.1 - 9.2e-05 21.9 1.2 9.2e-05 21.9 1.2 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 KDO29999.1 - 0.016 14.2 7.0 0.46 9.4 1.7 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO29999.1 - 0.92 9.7 29.9 1.7 8.8 11.5 3.0 2 1 0 2 2 2 0 EamA-like transporter family Amidinotransf PF02274.17 KDO30000.1 - 1.2e-10 41.0 0.0 1.2e-08 34.5 0.0 3.3 3 1 0 3 3 3 1 Amidinotransferase PAD_porph PF04371.15 KDO30000.1 - 0.0085 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Atx10homo_assoc PF09759.9 KDO30002.1 - 0.012 15.6 0.3 0.096 12.7 0.2 1.9 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain SF3A2 PF16835.5 KDO30003.1 - 6.4e-34 116.2 0.0 9.7e-34 115.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) ubiquitin PF00240.23 KDO30003.1 - 6.5e-07 29.0 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-met PF12874.7 KDO30003.1 - 1.8e-06 28.1 1.6 3.9e-06 27.0 1.1 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KDO30003.1 - 0.00023 21.1 0.1 0.00036 20.5 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein GARS_A PF01071.19 KDO30004.1 - 5.8e-75 251.3 0.0 9.3e-75 250.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 KDO30004.1 - 5.9e-43 146.7 0.0 1.4e-42 145.5 0.0 1.7 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 KDO30004.1 - 2.8e-35 120.9 0.4 2.8e-34 117.8 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KDO30004.1 - 4.9e-32 111.2 0.3 1.7e-30 106.2 0.0 3.2 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KDO30004.1 - 9.9e-30 102.7 0.6 3.5e-29 100.9 0.6 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KDO30004.1 - 8.3e-15 55.2 3.9 2.6e-14 53.6 2.4 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AICARFT_IMPCHas PF01808.18 KDO30004.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme ATP-grasp PF02222.22 KDO30004.1 - 1.8e-05 24.4 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KDO30004.1 - 3.4e-05 24.0 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KDO30004.1 - 4.2e-05 23.1 0.0 8.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 KDO30004.1 - 0.032 13.5 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RimK PF08443.11 KDO30004.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KDO30004.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Transmemb_17 PF09799.9 KDO30005.1 - 2.4e-25 89.2 11.9 2.8e-25 88.9 11.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein CCDC92 PF14916.6 KDO30006.1 - 0.0029 17.3 0.4 5.2 6.9 0.0 4.0 3 0 0 3 3 3 2 Coiled-coil domain of unknown function BRE1 PF08647.11 KDO30006.1 - 0.0058 16.7 4.4 0.0058 16.7 4.4 6.5 4 2 2 6 6 6 2 BRE1 E3 ubiquitin ligase HALZ PF02183.18 KDO30006.1 - 0.029 14.6 0.5 0.029 14.6 0.5 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Tup_N PF08581.10 KDO30006.1 - 1.1 9.6 0.0 1.1 9.6 0.0 7.5 5 4 5 10 10 10 0 Tup N-terminal Filament PF00038.21 KDO30006.1 - 1.4 8.5 60.2 0.08 12.5 0.4 5.2 2 1 2 5 5 5 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 KDO30006.1 - 1.5 8.8 46.6 0.079 13.0 3.5 6.3 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 KDO30006.1 - 2.7 7.9 11.0 1e+02 2.9 0.2 5.9 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LIN37 PF15306.6 KDO30006.1 - 9 6.5 8.8 0.52 10.5 1.2 2.8 2 0 0 2 2 2 0 LIN37 N_BRCA1_IG PF16158.5 KDO30007.1 - 1.7e-15 57.6 0.0 2.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 KDO30007.1 - 2e-10 40.3 0.4 4.8e-09 35.9 0.1 2.3 1 1 1 2 2 2 1 UBA-like domain CUE PF02845.16 KDO30007.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 CUE domain TAP_C PF03943.13 KDO30007.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Aa_trans PF01490.18 KDO30008.1 - 1.3e-11 43.9 16.0 1.3e-11 43.9 16.0 2.9 2 1 1 3 3 3 2 Transmembrane amino acid transporter protein Ras PF00071.22 KDO30009.1 - 0.00021 20.9 0.7 0.0066 16.1 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_28 PF13521.6 KDO30009.1 - 0.009 16.3 2.5 0.014 15.6 0.3 2.1 2 1 0 2 2 2 1 AAA domain DUF4572 PF15139.6 KDO30009.1 - 0.034 14.1 0.1 0.053 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) MMR_HSR1 PF01926.23 KDO30009.1 - 0.097 12.8 0.2 0.24 11.5 0.2 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO30009.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO30009.1 - 0.2 11.7 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IBR PF01485.21 KDO30010.1 - 3e-11 43.4 31.5 4.8e-06 26.7 2.7 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Ion_trans PF00520.31 KDO30011.1 - 2.7e-19 69.4 10.9 4.1e-19 68.8 10.9 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO30011.1 - 4.3e-16 58.8 0.0 8.9e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO30011.1 - 9.1e-12 44.8 7.5 9.1e-12 44.8 7.5 1.8 2 0 0 2 2 2 1 Ion channel TFIIA PF03153.13 KDO30011.1 - 0.015 15.3 2.2 0.028 14.5 2.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCIP PF13324.6 KDO30011.1 - 0.27 10.8 3.6 0.47 10.0 3.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF356 PF04009.12 KDO30011.1 - 0.59 10.4 3.2 0.53 10.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF356) IRK PF01007.20 KDO30011.1 - 1.9 8.3 4.2 4 7.2 4.2 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Peptidase_S9_N PF02897.15 KDO30012.1 - 1.5e-93 313.8 3.7 2.2e-93 313.3 3.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KDO30012.1 - 2.7e-62 210.0 0.5 5.7e-62 209.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Glyco_hydro_43 PF04616.14 KDO30012.1 - 0.011 15.0 0.3 0.027 13.8 0.3 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Methyltransf_25 PF13649.6 KDO30013.1 - 1e-05 26.2 0.0 5.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO30013.1 - 0.00025 20.9 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO30013.1 - 0.003 17.4 0.1 0.0042 16.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO30013.1 - 0.034 14.8 0.0 0.074 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KDO30013.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KDO30013.1 - 0.12 13.1 0.0 0.23 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KDO30013.1 - 0.12 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KDO30013.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Gar1 PF04410.14 KDO30014.1 - 1.4e-33 115.9 0.0 1.4e-33 115.9 0.0 1.4 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region UPF0183 PF03676.14 KDO30015.1 - 3.2e-85 286.8 0.0 4.5e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) RNA_pol_Rpb2_6 PF00562.28 KDO30016.1 - 7.9e-122 407.1 0.0 1.1e-121 406.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KDO30016.1 - 2.3e-54 184.0 0.0 3.1e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KDO30016.1 - 2e-33 114.6 0.4 5.9e-33 113.1 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KDO30016.1 - 4.8e-24 85.1 0.4 8.2e-24 84.3 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KDO30016.1 - 5.5e-19 68.2 0.7 1.5e-18 66.8 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KDO30016.1 - 2.3e-18 66.1 0.1 6.4e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KDO30016.1 - 8.2e-11 42.3 0.6 2.4e-10 40.8 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Hat1_N PF10394.9 KDO30017.1 - 1.7e-36 125.9 0.0 2.9e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KDO30017.1 - 1.9e-05 24.9 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO30017.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO30017.1 - 0.0033 17.8 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KDO30017.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Sec3-PIP2_bind PF15277.6 KDO30017.1 - 0.075 13.2 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Acetyltransf_9 PF13527.7 KDO30017.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4747 PF15931.5 KDO30017.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4747) Tcf25 PF04910.14 KDO30018.1 - 1.3e-67 228.3 0.2 1.8e-67 227.9 0.2 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF4927 PF16279.5 KDO30018.1 - 0.037 15.0 0.9 0.078 14.0 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4927) TPR_2 PF07719.17 KDO30018.1 - 0.037 14.1 0.1 0.26 11.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO30018.1 - 0.47 11.2 5.7 0.43 11.3 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SLX9 PF15341.6 KDO30018.1 - 1.1 9.6 7.2 1 9.8 5.3 1.9 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 GET2 PF08690.10 KDO30018.1 - 1.7 8.3 7.4 0.18 11.5 2.9 1.6 2 0 0 2 2 2 0 GET complex subunit GET2 TPR_14 PF13428.6 KDO30018.1 - 8.1 7.6 9.5 0.49 11.3 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ricin_B_lectin PF00652.22 KDO30019.1 - 4.9e-20 72.1 10.8 7.8e-15 55.2 1.1 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KDO30019.1 - 1.3e-06 28.1 4.1 0.015 14.8 0.2 2.6 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain Glyco_hydro_17 PF00332.18 KDO30019.1 - 7.8e-06 25.7 0.8 1.2e-05 25.1 0.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RicinB_lectin_2 PF14200.6 KDO30019.1 - 0.0035 18.0 9.6 0.016 15.9 2.0 2.8 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Defensin_5 PF18251.1 KDO30019.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 Fungal defensin Copsin DUF1336 PF07059.12 KDO30020.1 - 1.3e-46 159.5 0.0 2.3e-46 158.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1336) DUF4451 PF14616.6 KDO30020.1 - 0.075 13.2 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) DUF2054 PF10218.9 KDO30021.1 - 3e-30 105.0 17.2 3e-30 105.0 17.2 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2054) Methyltransf_31 PF13847.6 KDO30022.1 - 3.4e-14 52.9 0.0 2.9e-06 27.2 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KDO30022.1 - 2.5e-12 47.3 0.0 5.2e-11 43.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO30022.1 - 2.9e-12 47.1 0.0 8.2e-10 39.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO30022.1 - 3.5e-10 40.5 0.0 5.1e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO30022.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KDO30022.1 - 0.0023 17.4 0.0 0.0093 15.5 0.0 1.8 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Cyclin PF08613.11 KDO30023.1 - 1.6e-34 119.6 0.1 3.2e-34 118.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KDO30023.1 - 7.8e-11 41.8 0.1 1.3e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain B2-adapt-app_C PF09066.10 KDO30024.1 - 5.4e-05 23.3 0.0 0.0002 21.4 0.0 2.0 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Glycos_transf_2 PF00535.26 KDO30025.1 - 2.1e-23 83.0 0.0 3.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KDO30025.1 - 1.5e-12 47.9 0.0 2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KDO30025.1 - 4.1e-11 42.9 0.0 7.7e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KDO30025.1 - 2.4e-06 27.9 0.0 5.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 PB1 PF00564.24 KDO30026.1 - 0.0045 16.9 0.1 0.017 15.0 0.1 2.1 1 1 0 1 1 1 1 PB1 domain dsrm PF00035.26 KDO30027.1 - 7.3e-17 61.8 1.6 4.8e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif BSD PF03909.17 KDO30029.1 - 6.8e-06 26.0 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 BSD domain VPS28 PF03997.12 KDO30029.1 - 0.068 12.8 0.3 7.2 6.2 0.0 2.2 2 0 0 2 2 2 0 VPS28 protein DUF3829 PF12889.7 KDO30029.1 - 0.098 12.1 0.4 0.2 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) GCSF PF16647.5 KDO30029.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Rhodanese PF00581.20 KDO30030.1 - 1.3e-06 28.9 0.0 2.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain zf-H2C2_5 PF13909.6 KDO30030.1 - 0.088 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Med31 PF05669.12 KDO30031.1 - 3.3e-36 123.2 4.2 4e-36 122.9 4.2 1.1 1 0 0 1 1 1 1 SOH1 Exo_endo_phos PF03372.23 KDO30032.1 - 7.5e-09 35.5 0.0 2.2e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_2 PF00002.24 KDO30032.1 - 0.025 13.9 5.3 0.047 13.0 5.3 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Pkinase PF00069.25 KDO30033.1 - 3.2e-67 226.7 0.3 3.9e-67 226.4 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30033.1 - 3e-34 118.5 0.2 5e-34 117.8 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO30033.1 - 0.00013 21.4 0.5 0.00023 20.6 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO30033.1 - 0.022 14.1 0.4 0.051 12.9 0.0 1.8 2 1 0 2 2 2 0 Kinase-like Imm7 PF15585.6 KDO30033.1 - 0.028 14.7 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 Ank_2 PF12796.7 KDO30034.1 - 4.4e-28 97.7 0.3 9.7e-12 45.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30034.1 - 1.4e-20 73.4 1.5 1.1e-07 32.2 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30034.1 - 2.4e-19 67.4 1.7 0.0032 17.8 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO30034.1 - 6.5e-19 67.7 5.4 7.8e-06 26.1 0.0 5.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) UPF0020 PF01170.18 KDO30034.1 - 1.2e-12 48.0 0.0 1.7e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Ank PF00023.30 KDO30034.1 - 1.1e-11 44.7 4.4 0.088 13.3 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat N6_N4_Mtase PF01555.18 KDO30034.1 - 0.00047 19.9 0.0 0.099 12.3 0.0 2.2 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 KDO30034.1 - 0.04 13.2 0.0 0.94 8.7 0.0 2.1 2 0 0 2 2 2 0 N-6 DNA Methylase MTS PF05175.14 KDO30034.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 KDO30036.1 - 3.6e-56 190.5 0.0 4.9e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30036.1 - 1.6e-20 73.5 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO30036.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO30036.1 - 0.00059 19.2 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO30036.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KDO30036.1 - 0.25 10.3 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4140 PF13600.6 KDO30037.1 - 0.17 12.4 11.9 18 5.8 0.4 4.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.11 KDO30037.1 - 0.21 11.4 8.8 12 5.7 0.0 3.6 3 1 1 4 4 4 0 Phage minor structural protein GP20 Bap31_Bap29_C PF18035.1 KDO30037.1 - 1.2 9.2 6.3 16 5.6 0.4 3.2 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3437 PF11919.8 KDO30037.1 - 3.6 7.6 6.8 1.4 8.9 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Thioredoxin_8 PF13905.6 KDO30038.1 - 0.00052 20.3 0.0 0.001 19.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO30038.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin EF-hand_5 PF13202.6 KDO30039.1 - 0.051 13.1 0.3 1.5 8.5 0.0 2.8 2 0 0 2 2 2 0 EF hand ATP-synt_F PF01990.17 KDO30041.1 - 3.7e-31 107.3 0.2 4.3e-31 107.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Arf PF00025.21 KDO30042.1 - 3.3e-79 264.4 0.0 3.7e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO30042.1 - 1.2e-14 54.6 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO30042.1 - 9e-13 48.1 0.0 9.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KDO30042.1 - 9.3e-13 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KDO30042.1 - 4.2e-12 45.9 0.5 4.9e-08 32.5 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KDO30042.1 - 5.4e-09 35.8 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO30042.1 - 1.9e-05 24.7 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KDO30042.1 - 0.0094 15.3 0.1 0.016 14.5 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase HEAT PF02985.22 KDO30043.1 - 9e-10 38.0 0.0 0.012 15.8 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Pkinase PF00069.25 KDO30043.1 - 2e-08 34.0 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 KDO30043.1 - 5.1e-07 30.0 1.2 0.001 19.4 0.1 3.8 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KDO30043.1 - 0.0003 20.9 0.4 0.008 16.2 0.5 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO30043.1 - 0.013 16.0 2.8 1.8 9.2 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat CLASP_N PF12348.8 KDO30043.1 - 0.027 14.0 0.7 0.23 11.0 0.2 2.1 1 1 1 2 2 2 0 CLASP N terminal Adaptin_N PF01602.20 KDO30043.1 - 0.028 13.0 0.2 3.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KDO30043.1 - 0.18 12.4 0.2 1.4 9.6 0.0 2.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 KDO30044.1 - 1.6e-43 149.0 0.0 4.1e-43 147.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30044.1 - 3.5e-17 62.5 0.0 5.2e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KDO30044.1 - 0.021 13.8 0.1 0.048 12.6 0.0 1.5 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase DUF2183 PF09949.9 KDO30045.1 - 5.3e-07 29.9 0.0 3.1e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) ERCC4 PF02732.15 KDO30046.1 - 3.9e-19 69.4 0.0 7.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain GIY-YIG PF01541.24 KDO30046.1 - 0.068 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain SpoIISA_toxin PF14171.6 KDO30046.1 - 0.23 11.1 1.9 0.28 10.9 0.2 1.9 3 0 0 3 3 3 0 Toxin SpoIISA, type II toxin-antitoxin system LRR_8 PF13855.6 KDO30047.1 - 1.2e-38 130.6 51.2 2.8e-08 33.4 3.5 8.9 3 3 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KDO30047.1 - 8.4e-28 96.0 52.3 0.00023 21.5 2.8 11.5 6 3 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO30047.1 - 8.5e-08 31.9 14.4 0.051 13.1 0.1 5.4 2 2 4 7 7 7 4 Leucine-rich repeat LRR_1 PF00560.33 KDO30047.1 - 3e-07 30.1 33.5 0.49 11.1 0.2 13.5 15 2 1 16 16 16 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KDO30047.1 - 0.00087 19.3 0.5 4.6 7.4 0.0 5.3 5 1 1 6 6 6 1 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KDO30047.1 - 0.0066 16.4 40.2 1 9.6 0.1 12.1 13 0 0 13 13 13 2 Leucine Rich repeat DUF4813 PF16072.5 KDO30047.1 - 0.088 12.5 2.7 0.13 11.9 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) TMEM132D_C PF15706.5 KDO30048.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term BK_channel_a PF03493.18 KDO30049.1 - 4e-16 59.0 0.0 2.6e-14 53.2 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_C PF02080.21 KDO30049.1 - 3.9e-05 23.4 0.0 0.00015 21.6 0.0 2.0 1 0 0 1 1 1 1 TrkA-C domain Castor_Poll_mid PF06241.12 KDO30049.1 - 0.12 12.4 0.0 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel Ion_trans PF00520.31 KDO30050.1 - 1.4e-19 70.3 11.9 2.3e-19 69.6 11.9 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO30050.1 - 1.7e-11 43.9 2.0 1.7e-11 43.9 2.0 2.4 3 1 0 3 3 3 1 Ion channel WD40 PF00400.32 KDO30051.1 - 6.9e-25 86.8 13.0 3.7e-07 30.7 0.1 8.1 8 1 0 8 8 8 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KDO30051.1 - 1.5e-08 34.2 11.7 1.5e-08 34.2 11.7 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 KDO30051.1 - 4.7e-08 33.2 0.5 0.00044 20.5 0.1 4.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO30051.1 - 2.3e-06 27.6 0.3 0.015 15.2 0.1 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KDO30051.1 - 0.013 15.6 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region zinc_ribbon_16 PF17034.5 KDO30051.1 - 0.41 10.9 17.0 11 6.3 17.0 2.8 1 1 0 1 1 1 0 Zinc-ribbon like family zf-rbx1 PF12678.7 KDO30051.1 - 0.49 10.7 11.4 1.5 9.1 11.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_8 PF13181.6 KDO30052.1 - 0.0014 18.7 0.2 0.0063 16.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30052.1 - 0.055 13.6 0.2 0.21 11.8 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat End3 PF12761.7 KDO30052.1 - 0.12 12.6 3.6 1.2 9.2 0.5 2.3 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Dicty_CAR PF05462.11 KDO30053.1 - 9.9e-09 34.7 8.3 1.7e-08 34.0 8.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF2339 PF10101.9 KDO30053.1 - 0.015 13.9 7.6 0.023 13.3 7.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Exo_endo_phos PF03372.23 KDO30053.1 - 0.031 13.8 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Oxidored_q3 PF00499.20 KDO30053.1 - 0.13 12.0 1.3 0.19 11.5 0.3 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ECH_1 PF00378.20 KDO30054.1 - 2.2e-50 171.3 0.1 1.3e-49 168.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO30054.1 - 5.7e-28 98.4 0.4 2.9e-25 89.5 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SAPS PF04499.15 KDO30055.1 - 0.00034 19.5 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein WW PF00397.26 KDO30056.1 - 7.4e-16 57.9 7.2 6.4e-08 32.6 1.9 2.5 2 0 0 2 2 2 2 WW domain EF-hand_1 PF00036.32 KDO30056.1 - 1.2e-09 37.1 0.0 6.9e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO30056.1 - 2.7e-09 37.4 0.0 9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO30056.1 - 5.8e-09 35.2 0.5 0.00079 19.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KDO30056.1 - 7.3e-08 31.6 0.1 0.014 14.9 0.0 2.9 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 KDO30056.1 - 8e-06 25.5 0.4 1.5e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 Leucine rich repeat EF-hand_8 PF13833.6 KDO30056.1 - 9.7e-06 25.3 0.0 3.6e-05 23.5 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair IQ PF00612.27 KDO30056.1 - 0.00062 19.3 2.0 0.0016 18.1 2.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_4 PF12799.7 KDO30056.1 - 0.0024 18.2 1.9 0.074 13.5 0.1 2.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO30056.1 - 0.007 16.8 1.5 23 6.0 0.0 3.6 2 1 1 3 3 3 0 Leucine Rich Repeat mRNA_decap_C PF16741.5 KDO30056.1 - 0.062 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus PQQ_2 PF13360.6 KDO30056.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 PQQ-like domain Co_AT_N PF12557.8 KDO30056.1 - 0.47 10.4 8.7 0.056 13.4 3.3 2.1 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal TPR_2 PF07719.17 KDO30058.1 - 8e-28 94.3 11.8 0.00017 21.4 0.0 12.5 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30058.1 - 1.6e-25 87.6 20.2 0.006 17.3 0.1 11.9 5 3 9 14 14 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 KDO30058.1 - 3.3e-21 75.7 8.3 0.00077 20.1 0.2 8.2 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KDO30058.1 - 4.2e-20 72.0 9.5 0.00022 21.7 0.1 7.5 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30058.1 - 1.2e-14 53.3 3.7 0.0034 17.1 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30058.1 - 1.8e-14 52.6 11.4 0.023 14.9 0.1 9.7 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO30058.1 - 1.8e-13 49.8 6.9 0.13 12.6 0.0 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO30058.1 - 5.1e-13 49.1 19.0 0.036 14.4 0.2 9.7 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KDO30058.1 - 2.2e-10 40.5 12.6 0.52 11.1 0.0 9.1 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 KDO30058.1 - 1.8e-09 37.2 11.4 3.5e-06 26.4 1.7 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30058.1 - 7.2e-08 32.0 1.6 0.1 12.3 0.1 6.6 6 2 3 9 9 8 1 TPR repeat Suf PF05843.14 KDO30058.1 - 1.8e-07 31.5 1.0 0.00033 20.8 0.2 3.8 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_MalT PF17874.1 KDO30058.1 - 4.8e-07 29.5 9.5 0.00011 21.7 0.1 3.7 2 1 0 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 KDO30058.1 - 6.9e-07 29.4 7.7 0.002 18.3 0.1 5.2 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KDO30058.1 - 8.1e-07 29.1 11.6 0.29 11.3 0.1 6.8 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30058.1 - 5.5e-06 26.0 3.5 0.73 10.0 0.0 6.2 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO30058.1 - 0.00072 20.0 7.4 1.6 9.6 0.1 6.6 6 0 0 6 6 4 1 Tetratricopeptide repeat BTAD PF03704.17 KDO30058.1 - 0.016 15.6 7.5 10 6.5 0.1 4.8 3 2 2 5 5 5 0 Bacterial transcriptional activator domain PPR PF01535.20 KDO30058.1 - 0.042 14.1 6.5 93 3.6 0.0 7.2 9 1 0 9 9 7 0 PPR repeat Mad3_BUB1_I PF08311.12 KDO30058.1 - 0.045 13.7 8.4 32 4.5 0.0 6.0 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 ANAPC5 PF12862.7 KDO30058.1 - 0.087 12.9 0.1 2.2 8.4 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 MA3 PF02847.17 KDO30058.1 - 0.12 12.4 0.1 8.1 6.5 0.0 2.8 3 0 0 3 3 3 0 MA3 domain NARP1 PF12569.8 KDO30058.1 - 0.17 10.8 5.7 1.4 7.7 0.3 3.8 2 1 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KDO30058.1 - 0.32 10.9 15.9 1.1 9.2 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 KDO30058.1 - 1.8 8.9 5.2 31 5.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 KDO30059.1 - 0.022 14.6 0.2 0.022 14.6 0.2 2.3 3 0 0 3 3 3 0 F-box-like FBA PF04300.13 KDO30060.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box associated region Peptidase_S28 PF05577.12 KDO30061.1 - 1.5e-70 238.2 0.0 2.6e-69 234.1 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 KDO30061.1 - 3.6e-07 30.1 0.1 7e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO30061.1 - 4.4e-06 26.2 0.2 8e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 KDO30061.1 - 5.8e-05 21.9 0.0 0.00015 20.6 0.0 1.6 1 1 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KDO30061.1 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ank_4 PF13637.6 KDO30062.1 - 4.7e-17 62.1 1.6 1.1e-08 35.5 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO30062.1 - 2.5e-13 50.0 0.4 6.3e-09 35.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30062.1 - 7e-11 42.6 0.0 1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO30062.1 - 3.3e-10 39.3 0.2 0.00082 19.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO30062.1 - 6.6e-10 39.0 4.8 6.4e-05 23.2 0.4 2.6 3 0 0 3 3 3 2 Ankyrin repeat BK_channel_a PF03493.18 KDO30063.1 - 1.1e-20 73.6 0.1 5.9e-20 71.3 0.0 2.3 2 1 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO30063.1 - 2.2e-13 49.9 4.0 2.2e-13 49.9 4.0 2.3 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 KDO30063.1 - 0.00026 21.2 0.2 0.56 10.5 0.0 2.9 3 0 0 3 3 3 2 TrkA-N domain TrkA_C PF02080.21 KDO30063.1 - 0.038 13.8 0.0 2.7 7.9 0.0 3.0 2 0 0 2 2 2 0 TrkA-C domain Lig_chan PF00060.26 KDO30063.1 - 0.092 12.6 1.7 0.18 11.6 0.4 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel DUF2431 PF10354.9 KDO30064.1 - 1.9e-40 138.9 0.0 2.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Pkinase PF00069.25 KDO30065.1 - 9.9e-60 202.1 0.0 1.3e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30065.1 - 1.5e-26 93.3 0.3 2.3e-26 92.6 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KDO30065.1 - 0.0016 18.1 0.2 0.0052 16.4 0.1 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KDO30065.1 - 0.0023 17.3 0.1 0.058 12.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO30065.1 - 0.005 16.8 0.0 0.015 15.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO30065.1 - 0.012 15.1 0.4 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ribosomal_L7Ae PF01248.26 KDO30066.1 - 6.8e-27 93.0 0.6 8.6e-27 92.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family OTCace_N PF02729.21 KDO30067.1 - 1.1e-45 155.3 0.0 2.4e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KDO30067.1 - 2.2e-33 115.6 0.1 3.2e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NPBW PF15180.6 KDO30067.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Neuropeptides B and W Dynamin_M PF01031.20 KDO30068.1 - 4.9e-104 347.5 0.0 1.1e-103 346.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KDO30068.1 - 2.5e-58 196.8 0.1 6.4e-58 195.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KDO30068.1 - 1.1e-27 96.1 2.2 2.5e-27 94.9 1.6 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KDO30068.1 - 8.2e-05 22.7 0.1 0.00032 20.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO30068.1 - 0.014 15.8 0.1 0.51 10.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Pkinase PF00069.25 KDO30070.1 - 4.4e-64 216.4 0.0 6.2e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30070.1 - 1.7e-47 161.9 0.0 2.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO30070.1 - 0.00018 20.4 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO30070.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kinesin PF00225.23 KDO30071.1 - 1.1e-85 287.6 0.0 3.7e-85 285.8 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30071.1 - 5e-31 107.7 0.4 1.6e-28 99.5 0.0 3.6 3 1 0 3 3 3 1 Microtubule binding Myosin_head PF00063.21 KDO30072.1 - 3.1e-185 617.3 0.0 1e-173 579.2 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Ank_3 PF13606.6 KDO30072.1 - 1.6e-16 58.7 1.0 0.0021 18.4 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KDO30072.1 - 8.5e-16 58.3 0.1 2.8e-06 27.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO30072.1 - 1.4e-15 57.2 2.3 6.2e-05 23.2 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO30072.1 - 2.1e-14 53.7 0.1 3.7e-05 24.2 0.0 5.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO30072.1 - 2.1e-12 46.9 4.0 0.018 15.4 0.0 5.1 5 0 0 5 5 4 3 Ankyrin repeat FYVE PF01363.21 KDO30072.1 - 1.3e-11 44.4 7.7 4e-11 42.9 7.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 KDO30072.1 - 0.017 15.5 1.2 0.16 12.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KDO30072.1 - 0.069 13.5 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO30072.1 - 0.1 12.6 0.1 0.48 10.4 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RILP PF11461.8 KDO30072.1 - 0.21 11.8 1.6 0.48 10.7 1.6 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Takusan PF04822.13 KDO30072.1 - 0.45 10.4 2.1 1.1 9.1 2.1 1.6 1 0 0 1 1 1 0 Takusan IQ PF00612.27 KDO30072.1 - 0.67 9.9 45.0 0.33 10.9 1.3 6.1 5 0 0 5 5 5 0 IQ calmodulin-binding motif LRR_6 PF13516.6 KDO30073.1 - 5.5e-17 60.3 7.1 0.0045 16.9 0.0 8.5 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 KDO30073.1 - 0.00023 21.3 0.6 21 6.1 0.1 6.1 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KDO30073.1 - 0.031 14.0 9.4 11 5.8 0.2 5.9 4 1 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 KDO30073.1 - 0.63 10.5 9.4 1.5 9.4 0.2 4.9 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) ArfGap PF01412.18 KDO30074.1 - 1.3e-33 115.5 0.1 3.5e-33 114.2 0.0 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KDO30074.1 - 1.4e-23 83.9 0.3 2.5e-12 47.0 0.0 2.3 1 1 1 2 2 2 2 BAR domain of APPL family PH PF00169.29 KDO30074.1 - 3.6e-09 37.1 0.1 7.5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 KDO30074.1 - 1.7e-08 34.8 0.1 6.5e-08 33.0 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30074.1 - 5.3e-07 30.1 0.2 1.4e-06 28.7 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO30074.1 - 8.7e-06 25.9 0.1 2.9e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO30074.1 - 0.0018 18.7 0.1 0.0075 16.7 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat PH_9 PF15410.6 KDO30074.1 - 0.0023 18.3 2.8 0.44 10.9 1.7 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.6 KDO30074.1 - 0.0053 17.2 0.4 0.095 13.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.6 KDO30074.1 - 0.16 12.4 0.7 18 5.8 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain G6PD_C PF02781.16 KDO30075.1 - 5.5e-110 367.1 0.0 7.2e-110 366.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KDO30075.1 - 8.1e-55 186.2 0.0 1.2e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Cyto_heme_lyase PF01265.17 KDO30077.1 - 3.6e-54 184.3 5.4 1.4e-52 179.1 5.4 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribosomal_S6e PF01092.19 KDO30078.1 - 2.3e-58 195.6 1.5 2.3e-58 195.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Sec23_trunk PF04811.15 KDO30079.1 - 7.5e-66 222.1 0.0 1.1e-64 218.4 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KDO30079.1 - 3.2e-27 94.4 0.0 5.9e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KDO30079.1 - 1.8e-17 63.9 0.0 3.5e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KDO30079.1 - 3.3e-17 62.2 3.5 3.3e-17 62.2 3.5 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 KDO30079.1 - 0.00092 19.8 0.0 0.0028 18.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Gelsolin PF00626.22 KDO30079.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat MRNIP PF15749.5 KDO30079.1 - 0.04 14.6 0.3 0.075 13.8 0.3 1.4 1 0 0 1 1 1 0 MRN-interacting protein VWA PF00092.28 KDO30079.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_S28 PF05577.12 KDO30080.1 - 5.5e-78 262.7 0.0 6.6e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO30080.1 - 1.5e-07 30.5 0.1 2.9e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KDO30080.1 - 1.5e-05 24.4 0.1 9.8e-05 21.7 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO30080.1 - 8.6e-05 22.3 0.0 0.00027 20.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO30080.1 - 0.0025 17.3 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 KDO30080.1 - 0.047 12.9 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 KDO30080.1 - 0.28 11.8 12.5 1.4 9.5 10.3 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family PDZ PF00595.24 KDO30081.1 - 2.7e-18 66.1 0.0 1.5e-05 25.2 0.0 4.8 5 0 0 5 5 5 4 PDZ domain PDZ_2 PF13180.6 KDO30081.1 - 1e-07 32.2 0.5 0.24 11.8 0.1 4.3 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 KDO30081.1 - 7.6e-06 25.7 1.1 1.2 9.1 0.1 4.2 4 0 0 4 4 4 2 PDZ domain SH3_12 PF18129.1 KDO30081.1 - 0.17 12.0 0.5 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Xrn1 SH3-like domain Hexapep PF00132.24 KDO30082.1 - 1.6e-12 46.6 2.8 3.7e-07 29.6 0.3 4.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KDO30082.1 - 0.019 14.7 2.5 1.8 8.4 0.2 3.5 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase MccV PF17508.2 KDO30082.1 - 0.11 13.1 2.4 6.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Microcin V bacteriocin UPF0047 PF01894.17 KDO30083.1 - 3.4e-36 123.9 0.0 3.9e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Coa1 PF08695.10 KDO30084.1 - 4.6e-05 23.2 0.1 0.00061 19.5 0.0 2.2 1 1 1 2 2 2 1 Cytochrome oxidase complex assembly protein 1 DUF3040 PF11239.8 KDO30084.1 - 1.4 9.2 4.7 1.9 8.8 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Kinesin PF00225.23 KDO30085.1 - 1.8e-90 303.3 0.2 4.7e-90 301.9 0.2 1.8 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30085.1 - 3.3e-36 124.4 0.0 1.4e-35 122.4 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding TMF_TATA_bd PF12325.8 KDO30085.1 - 0.00012 22.3 2.9 0.00012 22.3 2.9 4.1 4 0 0 4 4 4 1 TATA element modulatory factor 1 TATA binding HDA2-3 PF11496.8 KDO30085.1 - 0.01 15.1 2.5 0.072 12.2 0.0 2.5 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Hemagglutinin PF00509.18 KDO30085.1 - 0.2 10.0 2.1 0.39 9.1 2.1 1.3 1 0 0 1 1 1 0 Haemagglutinin ATG16 PF08614.11 KDO30085.1 - 1.1 9.4 51.1 0.19 11.9 18.7 4.9 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KDO30085.1 - 1.1 8.6 36.0 0.21 11.0 1.8 4.4 2 1 2 4 4 4 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KDO30085.1 - 2 8.4 27.8 3.9 7.5 4.4 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 KDO30085.1 - 2.8 8.3 31.5 0.84 10.0 1.8 4.8 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Gp-FAR-1 PF05823.12 KDO30085.1 - 3.2 8.1 9.9 2.9 8.2 2.2 2.8 2 1 1 3 3 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-C4H2 PF10146.9 KDO30085.1 - 3.3 8.0 22.0 0.07 13.4 3.9 3.4 3 0 0 3 3 3 0 Zinc finger-containing protein DUF4611 PF15387.6 KDO30085.1 - 4.4 7.6 10.0 6.7 7.0 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF148 PF02520.17 KDO30085.1 - 6.7 6.9 19.2 0.053 13.6 2.2 3.8 3 1 0 3 3 3 0 Domain of unknown function DUF148 SlyX PF04102.12 KDO30085.1 - 9.1 7.0 19.5 15 6.2 0.5 5.9 4 1 2 6 6 6 0 SlyX FPP PF05911.11 KDO30085.1 - 9.5 4.3 44.9 0.041 12.1 5.0 4.0 3 1 1 4 4 4 0 Filament-like plant protein, long coiled-coil PPPI_inhib PF14895.6 KDO30086.1 - 4.5e-06 26.1 0.0 6.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor Pep3_Vps18 PF05131.14 KDO30088.1 - 1.8e-34 118.7 0.1 8e-34 116.6 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KDO30088.1 - 2.8e-11 43.5 8.6 4e-09 36.5 0.1 4.2 4 1 1 5 5 5 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KDO30088.1 - 0.022 15.2 0.1 0.25 11.8 0.0 2.7 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 ECH_2 PF16113.5 KDO30088.1 - 0.04 13.4 0.5 0.11 12.0 0.5 1.8 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase zf-RING_11 PF17123.5 KDO30088.1 - 0.12 12.2 0.4 0.31 10.8 0.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger Rotamase PF00639.21 KDO30088.1 - 0.18 12.8 0.4 0.77 10.8 0.4 2.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain TPR_7 PF13176.6 KDO30088.1 - 2.9 8.1 5.9 48 4.3 0.1 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat YabA PF06156.13 KDO30088.1 - 4.9 7.9 5.9 3.2 8.4 0.3 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Flavodoxin_2 PF02525.17 KDO30089.1 - 4.4e-25 88.6 0.0 1.3e-24 87.0 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KDO30089.1 - 1.4e-10 41.1 0.1 2.6e-10 40.3 0.1 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Mannosyl_trans PF05007.13 KDO30090.1 - 2.2e-73 247.3 21.1 3.5e-73 246.7 21.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KDO30090.1 - 9.7e-08 31.5 32.5 2.5e-07 30.1 32.3 1.6 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KDO30090.1 - 2.2e-06 27.5 12.3 2.2e-06 27.5 12.3 2.9 1 1 1 2 2 2 1 Glycosyltransferase family 87 Brix PF04427.18 KDO30091.1 - 9.3e-43 146.6 0.1 1.4e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 Brix domain EF-G-binding_N PF07299.11 KDO30091.1 - 0.15 12.6 0.3 0.33 11.5 0.3 1.5 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Cpn60_TCP1 PF00118.24 KDO30092.1 - 4.6e-164 546.7 1.6 5.8e-164 546.3 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_pol_A_exo1 PF01612.20 KDO30093.1 - 2e-15 56.9 0.4 3.4e-15 56.2 0.4 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_jaz PF12171.8 KDO30093.1 - 0.00036 20.7 1.1 0.55 10.6 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KDO30093.1 - 0.023 15.5 22.2 1.9 9.6 2.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KDO30093.1 - 0.025 14.3 2.9 0.033 13.9 1.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KDO30093.1 - 0.026 15.0 17.6 2 9.1 0.6 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 KDO30093.1 - 0.13 11.9 7.3 1.5 8.5 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KDO30093.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger NOB1_Zn_bind PF08772.11 KDO30093.1 - 4.3 7.6 10.6 0.96 9.7 0.3 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2_8 PF15909.5 KDO30093.1 - 5 7.5 11.0 12 6.3 5.0 3.3 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KDO30093.1 - 6.2 7.4 10.9 2.2 8.8 0.8 3.5 3 0 0 3 3 3 0 Zinc-finger double domain PDT PF00800.18 KDO30094.1 - 5.6e-17 62.1 1.4 3.5e-16 59.6 2.4 1.8 2 0 0 2 2 2 1 Prephenate dehydratase ACT PF01842.25 KDO30094.1 - 1.8e-05 24.4 0.0 5.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain Sec23_trunk PF04811.15 KDO30095.1 - 5.1e-75 252.2 0.0 7.6e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KDO30095.1 - 2.3e-26 91.6 0.0 4.4e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KDO30095.1 - 5e-17 61.7 4.0 9.5e-17 60.8 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KDO30095.1 - 5.5e-17 62.3 0.0 1e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KDO30095.1 - 6.8e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 KDO30095.1 - 0.0086 16.7 0.0 0.26 11.9 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain MRNIP PF15749.5 KDO30095.1 - 0.058 14.1 0.0 0.099 13.4 0.0 1.3 1 0 0 1 1 1 0 MRN-interacting protein Kinesin PF00225.23 KDO30097.1 - 3.7e-104 348.3 0.1 7.8e-104 347.2 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30097.1 - 6.4e-20 71.6 0.0 1.9e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 KDO30097.1 - 6.8e-15 55.7 6.5 2.3e-11 44.1 1.2 4.5 4 3 2 6 6 6 2 Kinesin-associated KIF1B PF12423.8 KDO30097.1 - 3.7e-05 24.0 0.0 3.7e-05 24.0 0.0 2.8 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 KDO30097.1 - 0.00013 22.2 0.0 0.00032 21.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain UbiA PF01040.18 KDO30098.1 - 2e-49 168.2 21.1 2.7e-49 167.7 21.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family TrbC PF04956.13 KDO30098.1 - 0.022 15.0 1.4 0.022 15.0 1.4 2.7 3 1 0 3 3 3 0 TrbC/VIRB2 family Fe_hyd_lg_C PF02906.14 KDO30099.1 - 7.2e-68 228.9 0.0 7.8e-67 225.5 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KDO30099.1 - 2.9e-08 33.6 0.0 5.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit ABC_tran PF00005.27 KDO30100.1 - 4.4e-54 182.7 0.0 2.9e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO30100.1 - 1.1e-35 123.4 40.8 3.9e-22 78.8 9.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KDO30100.1 - 6.3e-25 88.6 1.3 1.5e-10 41.4 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO30100.1 - 4.6e-05 23.3 0.1 0.3 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KDO30100.1 - 0.00028 20.8 0.8 0.046 13.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KDO30100.1 - 0.00075 20.1 5.5 0.0098 16.4 0.2 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO30100.1 - 0.00089 18.8 0.0 4.8 6.5 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO30100.1 - 0.00096 18.9 3.8 0.066 13.0 0.3 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO30100.1 - 0.024 14.7 0.3 6.9 6.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KDO30100.1 - 0.031 14.7 0.0 13 6.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KDO30100.1 - 0.045 14.0 0.4 11 6.4 0.0 4.2 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KDO30100.1 - 0.064 13.0 0.2 5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KDO30100.1 - 0.076 13.3 0.1 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO30100.1 - 0.083 13.4 0.3 45 4.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KDO30100.1 - 0.14 12.3 0.1 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KDO30100.1 - 0.16 11.8 2.9 3.4 7.4 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal Rad17 PF03215.15 KDO30100.1 - 0.23 11.3 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KDO30100.1 - 0.24 11.1 0.4 8.7 6.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO30100.1 - 0.62 10.4 4.6 8.8 6.7 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain Mg_chelatase PF01078.21 KDO30100.1 - 0.73 9.2 3.0 1.2 8.5 0.2 2.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KDO30100.1 - 1.3 9.0 2.9 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KDO30100.1 - 1.5 8.4 3.1 7 6.2 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain dNK PF01712.19 KDO30100.1 - 1.7 8.5 3.2 76 3.1 0.1 3.1 3 0 0 3 3 3 0 Deoxynucleoside kinase DUF87 PF01935.17 KDO30100.1 - 2.3 8.3 3.6 5.3 7.1 0.8 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain DEAD PF00270.29 KDO30101.1 - 9.8e-48 162.2 0.2 3.7e-47 160.4 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO30101.1 - 4.9e-24 84.8 0.0 1.2e-22 80.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KDO30101.1 - 4.3e-07 30.1 5.5 4.3e-07 30.1 5.5 2.3 2 1 0 2 2 2 1 DBP10CT (NUC160) domain ATP_sub_h PF10775.9 KDO30101.1 - 0.022 14.8 0.1 0.13 12.3 0.0 2.4 3 0 0 3 3 3 0 ATP synthase complex subunit h RNR_N PF08343.10 KDO30101.1 - 0.35 10.9 1.8 0.68 10.0 1.1 1.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal PI3_PI4_kinase PF00454.27 KDO30102.1 - 7.8e-47 160.2 0.0 1.3e-46 159.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KDO30102.1 - 5.6e-32 111.3 6.4 1.6e-31 109.8 6.4 1.8 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KDO30102.1 - 5e-17 61.4 0.0 1.8e-16 59.6 0.0 2.1 1 0 0 1 1 1 1 FATC domain UME PF08064.13 KDO30102.1 - 5.9e-15 55.0 6.8 1.3e-14 54.0 0.2 4.0 4 0 0 4 4 4 1 UME (NUC010) domain DUF3385 PF11865.8 KDO30102.1 - 0.0021 18.0 0.4 0.017 15.1 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KDO30102.1 - 0.021 14.4 7.6 0.044 13.3 0.1 3.0 3 0 0 3 3 3 0 Tti2 family TPR_12 PF13424.6 KDO30102.1 - 0.047 14.0 0.2 0.19 12.1 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30102.1 - 0.17 12.0 1.7 0.56 10.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30102.1 - 0.92 9.3 5.0 20 5.0 0.1 3.1 3 0 0 3 3 3 0 TPR repeat ANAPC4_WD40 PF12894.7 KDO30103.1 - 1.4e-05 25.3 0.0 0.067 13.5 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO30103.1 - 3.6e-05 24.5 1.0 0.06 14.2 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.6 KDO30103.1 - 0.0087 16.5 0.5 1.1 9.9 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain Dapper PF15268.6 KDO30103.1 - 0.42 9.4 1.3 3 6.6 0.7 2.0 1 1 1 2 2 2 0 Dapper Mito_carr PF00153.27 KDO30104.1 - 4e-31 106.8 7.0 8.6e-14 51.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ala_racemase_N PF01168.20 KDO30105.1 - 5e-28 98.2 0.3 6.5e-28 97.9 0.3 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KDO30105.1 - 6.1e-20 71.7 0.0 2.9e-17 63.1 0.0 2.9 2 1 1 3 3 3 2 Putative serine dehydratase domain Sedlin_N PF04628.13 KDO30106.1 - 6.9e-29 100.6 0.6 8.5e-29 100.3 0.6 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KDO30106.1 - 4.6e-06 26.6 0.2 5.2e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.23 KDO30107.1 - 2.7e-54 184.2 0.1 5.7e-54 183.2 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO30107.1 - 7.1e-16 58.5 0.0 2.3e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO30107.1 - 5.9e-10 39.4 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO30107.1 - 8.3e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KDO30107.1 - 3.3e-05 23.2 0.2 0.00032 20.0 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 KDO30107.1 - 0.0005 19.4 0.1 0.0089 15.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_12 PF13087.6 KDO30107.1 - 0.078 12.6 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 KDO30107.1 - 0.08 12.6 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 SWI2/SNF2 ATPase CAC1F_C PF16885.5 KDO30107.1 - 1.1 8.8 11.9 1.9 8.1 10.4 1.9 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term DUF3293 PF11697.8 KDO30108.1 - 2.1e-13 50.6 0.0 3.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3293) NOT2_3_5 PF04153.18 KDO30109.1 - 4.4e-25 88.3 6.2 9.8e-25 87.1 6.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Keratin_2_head PF16208.5 KDO30109.1 - 4.2 7.5 23.9 0.18 11.9 11.8 2.2 2 0 0 2 2 2 0 Keratin type II head DUF3563 PF12086.8 KDO30110.1 - 0.0088 15.8 0.2 0.02 14.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3563) DUF3490 PF11995.8 KDO30110.1 - 0.03 14.1 2.4 0.043 13.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Fez1 PF06818.15 KDO30110.1 - 0.047 14.2 10.2 0.085 13.3 10.2 1.5 1 1 0 1 1 1 0 Fez1 Ax_dynein_light PF10211.9 KDO30110.1 - 0.34 10.8 10.3 0.24 11.3 7.3 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain SlyX PF04102.12 KDO30110.1 - 6.6 7.4 9.2 39 5.0 7.1 2.7 1 1 1 2 2 2 0 SlyX YabA PF06156.13 KDO30110.1 - 9.4 6.9 7.1 9.5 6.9 3.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA HMG_box PF00505.19 KDO30112.1 - 1.8e-42 143.6 12.1 4.1e-21 75.2 5.5 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KDO30112.1 - 4.5e-26 91.2 10.9 6.6e-14 52.3 4.4 2.5 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 KDO30112.1 - 0.0014 18.6 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Ccdc124 PF06244.12 KDO30112.1 - 0.0029 18.1 2.1 0.041 14.4 0.2 3.3 1 1 1 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 MATalpha_HMGbox PF04769.12 KDO30112.1 - 0.0097 15.2 0.8 0.02 14.2 0.3 1.7 2 0 0 2 2 2 1 Mating-type protein MAT alpha 1 HMG-box Astro_capsid_p PF12226.8 KDO30112.1 - 0.41 9.8 11.7 0.6 9.2 11.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 KDO30112.1 - 6.1 6.1 14.1 1.3 8.3 10.2 1.8 2 0 0 2 2 2 0 NOA36 protein DUF4455 PF14643.6 KDO30113.1 - 2.3e-58 198.0 8.9 2.5e-36 125.3 5.5 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 KDO30113.1 - 7.5e-42 143.4 0.2 7.5e-42 143.4 0.2 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4456) RNA_pol_Rbc25 PF08292.12 KDO30114.1 - 4.2e-32 111.1 0.1 5.6e-32 110.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KDO30114.1 - 2.4e-14 53.5 0.2 4.2e-14 52.7 0.2 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KDO30114.1 - 0.0012 19.1 0.0 0.0048 17.2 0.0 2.0 1 1 0 1 1 1 1 S1 RNA binding domain UPF0182 PF03699.13 KDO30114.1 - 0.01 14.0 0.0 0.011 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Mito_carr PF00153.27 KDO30115.1 - 1.9e-65 216.8 5.8 1.1e-23 83.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hexapep PF00132.24 KDO30116.1 - 4.7e-11 42.0 8.4 0.0003 20.4 0.1 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KDO30116.1 - 0.0018 18.0 11.7 0.017 14.8 5.5 3.2 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Rhomboid PF01694.22 KDO30117.1 - 1.4e-23 83.5 12.5 2.4e-23 82.8 12.5 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KDO30117.1 - 0.07 13.7 0.1 0.14 12.7 0.1 1.6 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Pkinase PF00069.25 KDO30118.1 - 1.6e-65 221.1 0.0 3.1e-65 220.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 KDO30118.1 - 2.7e-55 187.8 0.0 2.7e-55 187.8 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C cNMP_binding PF00027.29 KDO30118.1 - 5e-45 151.5 0.2 1.8e-21 76.0 0.1 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO30118.1 - 3.1e-41 141.4 0.0 5.3e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO30118.1 - 0.00048 19.5 0.0 0.00091 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO30118.1 - 0.00078 19.4 0.8 1.5 8.7 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Myosin_head PF00063.21 KDO30119.1 - 9.9e-189 628.8 0.0 1.3e-188 628.4 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 KDO30119.1 - 6.7e-16 58.2 13.3 1.6e-15 57.0 13.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO30119.1 - 6.8e-05 23.5 0.0 0.00026 21.6 0.0 2.1 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO30119.1 - 0.0045 17.2 10.1 0.013 15.7 8.7 2.6 2 0 0 2 2 2 1 FYVE-type zinc finger AAA_22 PF13401.6 KDO30119.1 - 0.0082 16.4 0.0 0.089 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KDO30119.1 - 0.012 16.0 1.2 0.084 13.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.26 KDO30119.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 KDO30119.1 - 0.16 12.5 0.1 0.79 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KDO30122.1 - 2.3e-08 34.5 0.9 0.005 17.7 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ PF01011.21 KDO30122.1 - 0.0014 18.4 0.3 0.025 14.5 0.1 3.0 4 0 0 4 4 4 1 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 KDO30122.1 - 0.0026 18.0 0.0 2 8.8 0.0 3.7 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KDO30122.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIIC_delta PF12657.7 KDO30122.1 - 0.051 13.5 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term GAS PF13851.6 KDO30123.1 - 2.5e-64 216.3 29.5 2.5e-64 216.3 29.5 3.4 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding MCPVI PF02993.14 KDO30123.1 - 0.023 14.6 0.6 0.066 13.0 0.6 1.7 1 0 0 1 1 1 0 Minor capsid protein VI Sigma54_activ_2 PF14532.6 KDO30123.1 - 2.8 8.0 6.3 1.2 9.3 0.5 3.1 2 1 1 3 3 3 0 Sigma-54 interaction domain LXG PF04740.12 KDO30124.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Gag_p10 PF02337.17 KDO30124.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral GAG p10 protein TBX PF12598.8 KDO30124.1 - 0.13 13.0 6.8 0.18 12.6 2.2 2.4 2 0 0 2 2 2 0 T-box transcription factor Methyltransf_23 PF13489.6 KDO30125.1 - 1.6e-24 86.6 0.0 2.1e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO30125.1 - 7.8e-18 64.9 0.1 1.4e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO30125.1 - 8.5e-15 55.2 0.1 1.6e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO30125.1 - 8.5e-15 55.3 0.1 1.4e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO30125.1 - 5.8e-14 52.2 0.0 7.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO30125.1 - 1.2e-09 37.9 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KDO30125.1 - 1.3e-09 37.9 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KDO30125.1 - 1.8e-05 23.9 0.0 2.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KDO30125.1 - 8.2e-05 22.0 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KDO30125.1 - 0.00017 21.2 0.1 0.00029 20.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KDO30125.1 - 0.00027 20.6 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 KDO30125.1 - 0.0004 20.0 0.0 0.00054 19.5 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 KDO30125.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KDO30125.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KDO30125.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase MetW PF07021.12 KDO30125.1 - 0.0066 16.1 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 KDO30125.1 - 0.013 15.1 0.0 0.043 13.5 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 KDO30125.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KDO30125.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase PDZ_6 PF17820.1 KDO30126.1 - 3.2e-05 23.7 0.0 8.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO30126.1 - 0.0021 18.4 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO30126.1 - 0.042 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF348 PF03990.14 KDO30126.1 - 5.4 6.8 6.0 1.1 9.1 1.6 2.2 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain COPI_C PF06957.11 KDO30127.1 - 4e-100 335.4 2.4 5.7e-100 334.9 2.4 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KDO30127.1 - 4.5e-99 332.5 0.0 7.2e-99 331.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KDO30127.1 - 3.9e-40 135.1 20.1 6.6e-09 36.3 0.3 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30127.1 - 2.6e-11 43.6 1.2 8.1e-05 22.8 0.1 5.8 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KDO30128.1 - 2e-06 27.5 0.0 4.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.6 KDO30128.1 - 0.013 15.2 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nup35_RRM_2 PF14605.6 KDO30128.1 - 0.035 14.1 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KDO30128.1 - 0.036 14.8 0.1 0.1 13.3 0.1 1.9 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KDO30128.1 - 0.18 12.3 2.1 0.45 11.1 2.1 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SOG2 PF10428.9 KDO30128.1 - 6.1 5.9 14.3 10 5.2 14.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein zf-B_box PF00643.24 KDO30130.1 - 3.8e-05 23.7 8.0 7.7e-05 22.8 8.0 1.5 1 0 0 1 1 1 1 B-box zinc finger ZZ PF00569.17 KDO30130.1 - 0.044 13.6 6.2 0.082 12.7 6.2 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type CDKN3 PF05706.12 KDO30130.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) IBR PF01485.21 KDO30130.1 - 5 7.4 8.8 0.31 11.3 3.3 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CEBP_ZZ PF16366.5 KDO30130.1 - 9.2 6.6 9.5 1.5 9.1 5.3 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Gp_dh_C PF02800.20 KDO30131.1 - 4.5e-35 120.6 0.0 7.1e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KDO30131.1 - 2.4e-19 69.5 0.1 5.9e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NDUF_B7 PF05676.13 KDO30132.1 - 1.9e-25 88.3 4.1 2.3e-25 88.1 4.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KDO30132.1 - 0.0026 17.7 2.8 0.0039 17.2 2.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KDO30132.1 - 0.094 13.0 3.8 1.4 9.2 4.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Hydrolase PF00702.26 KDO30133.1 - 7.3e-48 163.6 2.1 1.3e-47 162.8 2.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO30133.1 - 1.5e-33 115.8 1.1 1.5e-33 115.8 1.1 3.1 4 1 0 4 4 4 1 E1-E2 ATPase HMA PF00403.26 KDO30133.1 - 5.8e-26 90.7 9.7 3.8e-06 27.3 0.2 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KDO30133.1 - 5e-05 23.2 1.5 0.0025 17.6 1.2 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO30133.1 - 0.00071 20.0 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KDO30133.1 - 0.11 12.7 0.1 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KDO30133.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GAS PF13851.6 KDO30134.1 - 0.00021 20.7 23.4 0.00021 20.7 23.4 4.0 1 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KDO30134.1 - 0.0024 18.1 73.4 0.016 15.5 12.5 5.7 1 1 5 6 6 6 3 JNK_SAPK-associated protein-1 Leu_zip PF15294.6 KDO30134.1 - 2 7.9 54.8 0.087 12.3 26.1 3.1 1 1 1 3 3 3 0 Leucine zipper Baculo_PEP_C PF04513.12 KDO30134.1 - 4.8 7.2 21.9 1.5 8.9 2.5 4.7 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus E6 PF00518.17 KDO30134.1 - 4.9 7.6 6.3 11 6.5 1.0 2.8 2 0 0 2 2 2 0 Early Protein (E6) DHHC PF01529.20 KDO30136.1 - 1e-23 83.9 5.4 1e-23 83.9 5.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF202 PF02656.15 KDO30136.1 - 4.2 7.9 8.4 15 6.1 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2040 PF09745.9 KDO30137.1 - 7.8e-33 113.1 12.2 7.8e-33 113.1 12.2 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) SHIPPO-rpt PF07004.12 KDO30138.1 - 0.089 13.7 8.6 4.8 8.3 0.5 3.9 3 1 0 3 3 3 0 Sperm-tail PG-rich repeat Pkinase PF00069.25 KDO30139.1 - 5.8e-69 232.4 0.0 7.4e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30139.1 - 8.4e-35 120.3 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO30139.1 - 0.00022 20.7 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO30139.1 - 0.00043 19.7 0.1 0.0012 18.2 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO30139.1 - 0.0012 18.8 0.7 0.0035 17.3 0.6 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KDO30139.1 - 0.0046 16.1 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KDO30139.1 - 0.0046 15.9 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO30139.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KDO30139.1 - 0.27 10.8 1.3 0.83 9.2 0.2 1.9 1 1 1 2 2 2 0 RIO1 family ADK PF00406.22 KDO30140.1 - 1.7e-53 180.8 0.1 1.1e-40 139.2 0.0 2.8 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 KDO30140.1 - 4.2e-28 98.5 1.8 4.6e-21 75.7 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 KDO30140.1 - 9.4e-08 32.7 0.8 7e-05 23.4 0.0 4.1 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 KDO30140.1 - 8.4e-06 26.0 0.7 0.00012 22.2 0.0 3.4 2 1 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KDO30140.1 - 0.026 14.5 0.0 0.095 12.7 0.0 2.0 1 0 0 1 1 1 0 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 KDO30140.1 - 0.047 13.4 0.1 0.047 13.4 0.1 3.3 3 1 0 4 4 4 0 Cytidylate kinase DivIC PF04977.15 KDO30140.1 - 0.12 12.2 6.6 0.44 10.4 0.8 3.8 2 1 1 3 3 3 0 Septum formation initiator DUF4363 PF14276.6 KDO30140.1 - 3.8 7.7 5.7 1.8 8.7 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) BT1 PF03092.16 KDO30141.1 - 1e-46 159.3 13.5 3.6e-31 108.0 0.5 2.5 2 1 1 3 3 3 2 BT1 family MFS_1 PF07690.16 KDO30141.1 - 7.3e-06 25.1 49.0 0.00016 20.7 30.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Skp1 PF01466.19 KDO30142.1 - 1.3e-27 95.6 0.4 2.8e-27 94.5 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KDO30142.1 - 1.6e-23 82.6 0.8 2.5e-23 82.0 0.8 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KDO30142.1 - 0.00021 21.5 0.4 0.0013 18.9 0.4 2.0 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_L3 PF00297.22 KDO30143.1 - 2.3e-181 602.7 6.5 2.6e-181 602.5 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 ANAPC4_WD40 PF12894.7 KDO30144.1 - 0.0008 19.7 0.0 0.0027 18.0 0.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Golgin_A5 PF09787.9 KDO30145.1 - 5.6e-05 22.7 21.4 0.00031 20.3 17.9 2.1 1 1 1 2 2 2 2 Golgin subfamily A member 5 DUF1664 PF07889.12 KDO30145.1 - 0.00062 19.8 0.8 0.00062 19.8 0.8 2.6 2 1 0 3 3 3 1 Protein of unknown function (DUF1664) DASH_Spc34 PF08657.10 KDO30145.1 - 0.0063 16.3 3.2 0.013 15.3 3.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Spc34 Cep57_CLD PF14073.6 KDO30145.1 - 0.0091 16.0 7.2 0.0091 16.0 7.2 2.8 1 1 0 2 2 1 1 Centrosome localisation domain of Cep57 CLZ PF16526.5 KDO30145.1 - 0.025 14.9 14.8 1.3 9.5 3.6 3.7 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SNCAIP_SNCA_bd PF16700.5 KDO30145.1 - 0.11 12.2 3.0 0.32 10.8 0.5 2.4 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Exonuc_VII_L PF02601.15 KDO30145.1 - 1.1 8.7 14.9 0.25 10.9 9.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 KDO30145.1 - 1.4 8.0 14.3 6.3 5.8 0.4 2.9 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT20 PF14931.6 KDO30145.1 - 1.9 8.7 16.3 0.72 10.0 1.8 3.0 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 FapA PF03961.13 KDO30145.1 - 2.6 6.5 12.1 0.073 11.7 4.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 KDO30145.1 - 3.1 8.2 7.0 7.3 7.1 0.5 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KDO30145.1 - 3.9 8.2 18.6 30 5.3 0.2 4.8 2 1 2 5 5 5 0 SlyX OmpH PF03938.14 KDO30145.1 - 4.7 7.5 24.6 10 6.4 0.6 3.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Penicil_amidase PF01804.18 KDO30145.1 - 6 5.7 9.4 2.1 7.2 6.1 1.6 1 1 1 2 2 2 0 Penicillin amidase Prefoldin_2 PF01920.20 KDO30145.1 - 6.3 6.8 22.9 7.6 6.5 0.2 5.1 3 1 0 4 4 4 0 Prefoldin subunit COG5 PF10392.9 KDO30146.1 - 1.1e-14 54.7 4.6 1.1e-13 51.4 1.7 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Zw10 PF06248.13 KDO30146.1 - 4e-05 22.4 2.1 8.4e-05 21.3 2.1 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG7 PF10191.9 KDO30146.1 - 0.0022 16.3 0.9 0.0046 15.3 0.9 1.4 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DUF1664 PF07889.12 KDO30146.1 - 0.11 12.6 1.0 0.29 11.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KDO30146.1 - 0.14 12.3 1.9 0.34 11.0 0.9 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KDO30146.1 - 0.14 12.2 0.2 0.44 10.7 0.2 1.9 1 0 0 1 1 1 0 Vps51/Vps67 LXG PF04740.12 KDO30146.1 - 0.24 11.1 3.0 0.4 10.3 1.4 2.1 3 0 0 3 3 3 0 LXG domain of WXG superfamily Sec8_exocyst PF04048.14 KDO30146.1 - 1.7 8.5 5.8 0.69 9.8 1.9 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Med21 PF11221.8 KDO30147.1 - 8.7e-14 52.0 10.7 3.1e-09 37.2 4.2 2.0 1 1 1 2 2 2 2 Subunit 21 of Mediator complex Med9 PF07544.13 KDO30147.1 - 0.0057 16.7 0.4 0.017 15.2 0.1 1.8 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Xpo1 PF08389.12 KDO30148.1 - 0.0048 17.0 0.1 0.017 15.2 0.1 1.9 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KDO30148.1 - 0.02 14.8 0.1 0.075 13.0 0.0 2.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain DUF724 PF05266.14 KDO30150.1 - 0.012 15.4 1.9 0.019 14.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Asp_Arg_Hydrox PF05118.15 KDO30150.1 - 0.036 13.9 2.2 0.054 13.3 0.4 2.1 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase DUF2048 PF09752.9 KDO30150.1 - 0.049 12.7 0.6 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Baculo_p24 PF05073.12 KDO30150.1 - 0.16 11.7 0.4 0.24 11.2 0.4 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein PEP-utilisers_N PF05524.13 KDO30150.1 - 0.52 10.5 3.0 5 7.3 0.0 2.8 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal BBP1_C PF15272.6 KDO30151.1 - 0.017 15.0 2.7 0.028 14.3 2.7 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF4472 PF14739.6 KDO30152.1 - 0.18 12.6 4.8 0.34 11.7 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Band_7 PF01145.25 KDO30153.1 - 2.5e-25 89.5 3.8 4.7e-25 88.6 1.6 2.2 1 1 1 2 2 2 1 SPFH domain / Band 7 family ATP-synt_ab_C PF00306.27 KDO30153.1 - 0.0076 16.6 0.9 0.013 15.8 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain COX14 PF14880.6 KDO30154.1 - 3.9e-08 33.0 0.6 5.1e-08 32.6 0.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly EamA PF00892.20 KDO30155.1 - 4.4e-10 39.9 34.2 1.9e-05 24.9 11.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family NTP_transf_3 PF12804.7 KDO30155.1 - 7.4e-05 23.1 0.2 0.00019 21.8 0.2 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Gram_pos_anchor PF00746.21 KDO30155.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif AAA PF00004.29 KDO30156.1 - 9.1e-39 132.9 0.0 2.6e-38 131.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO30156.1 - 2.1e-10 40.2 0.2 8.9e-10 38.2 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 KDO30156.1 - 8.1e-06 25.7 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KDO30156.1 - 0.00035 20.8 0.5 0.015 15.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain LisH PF08513.11 KDO30156.1 - 0.0006 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 LisH TIP49 PF06068.13 KDO30156.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KDO30156.1 - 0.0021 18.5 0.0 0.0094 16.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain LisH_TPL PF17814.1 KDO30156.1 - 0.0032 17.1 0.1 0.007 16.0 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain AAA_14 PF13173.6 KDO30156.1 - 0.0045 17.0 0.0 0.0099 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KDO30156.1 - 0.0054 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KDO30156.1 - 0.0094 16.3 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KDO30156.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KDO30156.1 - 0.013 15.5 0.1 0.045 13.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO30156.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KDO30156.1 - 0.02 14.4 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KDO30156.1 - 0.027 14.4 0.0 0.091 12.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KDO30156.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KDO30156.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KDO30156.1 - 0.037 13.6 0.1 0.4 10.2 0.1 2.3 1 1 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KDO30156.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 KDO30156.1 - 0.066 13.8 0.0 0.32 11.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KDO30156.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KDO30156.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase DAO PF01266.24 KDO30157.1 - 8.6e-43 147.3 0.1 9.8e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KDO30157.1 - 2.4e-05 24.4 0.1 0.0051 16.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KDO30157.1 - 6.7e-05 22.3 0.3 0.23 10.6 0.9 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO30157.1 - 0.0056 15.8 0.2 2.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KDO30157.1 - 0.017 15.7 0.5 0.041 14.4 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO30157.1 - 0.079 13.2 0.8 0.22 11.8 0.8 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KDO30157.1 - 0.13 11.1 0.3 0.19 10.5 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 KDO30157.1 - 0.15 11.7 0.4 0.27 10.9 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KDO30157.1 - 0.22 10.6 0.0 2 7.4 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1751 PF08551.10 KDO30158.1 - 5.5e-08 33.3 2.6 8.9e-08 32.6 2.6 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KDO30158.1 - 7.9e-05 22.7 4.7 0.00013 22.0 4.7 1.3 1 0 0 1 1 1 1 Rhomboid family DUF2637 PF10935.8 KDO30158.1 - 0.025 14.5 0.5 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Pribosyltran_N PF13793.6 KDO30159.1 - 2.1e-50 169.5 0.2 1.4e-49 166.9 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KDO30159.1 - 4.7e-27 95.2 0.1 1.4e-26 93.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KDO30159.1 - 1.6e-14 53.7 0.4 5.6e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KDO30159.1 - 0.017 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase FG-GAP_2 PF14312.6 KDO30160.1 - 3.6e-67 222.4 73.8 7.4e-11 42.1 0.6 14.5 14 0 0 14 14 14 12 FG-GAP repeat Calx-beta PF03160.14 KDO30160.1 - 1.5e-10 41.1 0.1 0.028 14.6 0.0 4.9 4 0 0 4 4 4 3 Calx-beta domain DUF4957 PF16318.5 KDO30161.1 - 0.0077 16.2 0.2 0.11 12.4 0.0 2.5 1 1 0 2 2 2 1 Domain of unknown function (DUF4957) GCP_C_terminal PF04130.13 KDO30162.1 - 8.6e-83 278.3 9.6 1.4e-82 277.7 9.6 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KDO30162.1 - 2.5e-65 221.1 0.1 9e-65 219.3 0.0 2.0 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF3365 PF11845.8 KDO30162.1 - 0.02 15.2 0.0 0.078 13.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) DHHC PF01529.20 KDO30163.1 - 8.9e-35 119.7 9.5 8.9e-35 119.7 9.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Wzy_C PF04932.15 KDO30163.1 - 0.74 9.4 3.6 1 9.0 0.0 2.2 2 1 0 2 2 2 0 O-Antigen ligase MFS_1 PF07690.16 KDO30164.1 - 1.6e-30 106.2 43.9 5.9e-25 87.9 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KDO30164.1 - 7.9e-08 31.6 15.8 0.00014 20.9 1.3 2.1 1 1 1 2 2 2 2 MFS_1 like family HgmA PF04209.13 KDO30165.1 - 1.3e-205 683.0 1.5 1.5e-205 682.9 1.5 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MFS_1 PF07690.16 KDO30166.1 - 3.1e-13 49.4 33.1 4e-10 39.2 11.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily HEAT PF02985.22 KDO30167.1 - 2.1e-19 67.9 1.2 1.1e-06 28.4 0.0 8.7 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KDO30167.1 - 6.7e-17 61.6 1.5 6.9e-11 42.4 0.0 7.4 8 2 2 10 10 9 1 HEAT-like repeat IFRD PF05004.13 KDO30167.1 - 1.2e-11 44.3 1.1 0.00056 19.1 0.3 5.2 2 1 3 6 6 6 2 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KDO30167.1 - 1.2e-09 38.4 3.1 0.0019 18.5 0.0 7.2 5 2 3 8 8 8 1 HEAT repeats IBN_N PF03810.19 KDO30167.1 - 1.2e-07 31.6 1.6 0.00041 20.2 0.1 4.2 4 0 0 4 4 4 2 Importin-beta N-terminal domain MMS19_C PF12460.8 KDO30167.1 - 2.8e-07 30.0 0.0 0.026 13.6 0.0 5.1 3 1 2 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.23 KDO30167.1 - 3.1e-06 27.0 6.8 0.00048 20.1 0.0 6.8 8 0 0 8 8 7 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KDO30167.1 - 6.7e-06 26.1 0.7 5.9 6.8 0.0 5.6 3 3 4 7 7 7 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KDO30167.1 - 1.6e-05 25.0 0.1 0.021 14.9 0.0 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KDO30167.1 - 2.5e-05 23.1 0.3 0.22 10.0 0.0 3.6 4 1 0 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 KDO30167.1 - 0.0002 21.0 0.0 2.4 7.7 0.0 4.3 3 2 0 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KDO30167.1 - 0.00037 21.0 6.3 9.5 6.9 0.7 7.1 5 3 4 9 9 9 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 KDO30167.1 - 0.0017 17.7 0.2 0.035 13.3 0.0 2.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.9 KDO30167.1 - 0.016 13.7 0.3 2.2 6.7 0.1 3.0 2 2 1 3 3 3 0 Proteasome non-ATPase 26S subunit Sec7_N PF12783.7 KDO30167.1 - 0.034 14.0 0.1 4.9 7.0 0.1 3.4 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Fanconi_A_N PF15865.5 KDO30167.1 - 0.044 13.2 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Methyltr_RsmB-F PF01189.17 KDO30168.1 - 1.4e-35 122.8 0.0 2.3e-34 118.8 0.0 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F zf-CCHC_2 PF13696.6 KDO30168.1 - 0.00066 19.4 1.3 0.00066 19.4 1.3 1.9 2 0 0 2 2 2 1 Zinc knuckle FtsJ PF01728.19 KDO30168.1 - 0.00079 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PAP2 PF01569.21 KDO30169.1 - 7.5e-08 32.2 5.1 7.5e-08 32.2 5.1 2.2 1 1 2 3 3 3 1 PAP2 superfamily Presenilin PF01080.17 KDO30170.1 - 9.5e-95 317.7 16.6 2.4e-94 316.4 16.6 1.5 1 1 0 1 1 1 1 Presenilin MRAP PF15183.6 KDO30170.1 - 0.0057 16.6 0.4 0.025 14.5 0.4 2.1 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family TMEM132D_C PF15706.5 KDO30170.1 - 0.046 13.5 4.3 0.51 10.2 0.3 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Kazal_2 PF07648.15 KDO30171.1 - 3.4e-18 65.5 12.9 9.5e-10 38.5 2.6 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KDO30171.1 - 2.1e-16 59.7 12.1 5.6e-08 32.7 2.5 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain ING PF12998.7 KDO30172.1 - 0.012 16.1 1.2 0.012 16.1 1.2 4.5 4 0 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding ATG16 PF08614.11 KDO30172.1 - 0.032 14.5 83.7 0.17 12.1 7.1 6.2 1 1 4 6 6 6 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KDO30172.1 - 0.19 12.4 0.1 0.19 12.4 0.1 8.2 6 3 2 8 8 8 0 SlyX SHE3 PF17078.5 KDO30172.1 - 2.1 8.0 47.6 0.0094 15.7 18.0 3.8 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 CCDC144C PF14915.6 KDO30172.1 - 7.3 5.6 57.4 0.045 12.9 13.7 3.7 1 1 1 3 3 3 0 CCDC144C protein coiled-coil region DUF948 PF06103.11 KDO30172.1 - 8 6.8 26.6 0.26 11.6 0.4 4.9 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) SAWADEE PF16719.5 KDO30174.1 - 0.091 12.8 2.3 0.16 11.9 2.3 1.3 1 0 0 1 1 1 0 SAWADEE domain Pkinase PF00069.25 KDO30176.1 - 2.1e-45 155.2 0.2 3.8e-23 82.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30176.1 - 1.4e-15 57.3 0.1 4.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO30176.1 - 0.018 13.8 0.3 0.06 12.1 0.3 1.8 1 1 0 1 1 1 0 Fungal protein kinase NARP1 PF12569.8 KDO30176.1 - 0.033 13.1 2.5 0.062 12.2 2.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RIO1 PF01163.22 KDO30176.1 - 0.052 13.2 0.1 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 KDO30176.1 - 0.14 12.1 2.1 4.7 7.1 0.6 3.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family EF-hand_7 PF13499.6 KDO30177.1 - 3.2e-08 33.9 0.7 4e-07 30.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO30177.1 - 1.1e-05 24.6 0.1 0.017 14.6 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO30177.1 - 1.7e-05 24.4 0.3 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO30177.1 - 2.5e-05 24.0 0.0 0.72 9.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO30177.1 - 0.00029 21.1 0.0 0.00092 19.5 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain DUF3127 PF11325.8 KDO30177.1 - 0.078 13.2 2.3 0.086 13.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) Ndufs5 PF10200.9 KDO30177.1 - 3.3 8.0 5.8 0.4 11.0 0.5 2.2 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pkinase PF00069.25 KDO30178.1 - 3.9e-71 239.5 0.0 4.6e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30178.1 - 2.7e-34 118.6 0.0 3.6e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KDO30178.1 - 9.6e-08 32.6 1.0 1.8e-07 31.7 1.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KDO30178.1 - 0.00016 21.1 0.0 0.00033 20.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KDO30178.1 - 0.0019 17.9 0.1 0.59 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KDO30178.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO30178.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO30178.1 - 0.074 12.0 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO30178.1 - 0.14 11.1 0.1 1.1 8.3 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Methyltransf_16 PF10294.9 KDO30179.1 - 3.5e-19 69.2 0.1 1.5e-11 44.4 0.1 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Ank_4 PF13637.6 KDO30179.1 - 5.7e-18 65.1 1.7 2.2e-07 31.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30179.1 - 6.4e-18 65.1 3.5 1.1e-16 61.1 0.6 3.2 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO30179.1 - 8.2e-13 48.2 6.6 2.7e-05 24.4 0.1 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KDO30179.1 - 1.2e-12 46.8 2.2 5.7e-05 23.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO30179.1 - 5.7e-12 45.6 1.3 8.2e-05 22.8 0.5 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 KDO30179.1 - 3.5e-09 36.6 10.8 7.5e-09 35.5 10.8 1.6 1 0 0 1 1 1 1 MYND finger Methyltransf_23 PF13489.6 KDO30179.1 - 7.6e-05 22.6 0.0 0.00023 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO30179.1 - 0.0029 18.2 1.3 1.8 9.3 0.1 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO30179.1 - 0.0039 17.9 0.1 0.23 12.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KDO30179.1 - 0.0055 16.3 1.1 0.025 14.1 0.0 2.6 5 0 0 5 5 5 1 Methyltransferase small domain zf-C6H2 PF15801.5 KDO30179.1 - 0.027 14.8 3.1 0.072 13.4 3.1 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Met_10 PF02475.16 KDO30179.1 - 0.044 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HMA PF00403.26 KDO30180.1 - 0.17 12.4 0.1 0.29 11.6 0.1 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain HEAT PF02985.22 KDO30184.1 - 1.5e-11 43.5 11.9 0.65 10.4 0.0 8.7 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 KDO30184.1 - 3.6e-08 33.7 9.9 0.26 11.7 0.1 5.7 5 2 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 KDO30184.1 - 0.00066 20.1 10.9 0.99 10.0 0.1 7.5 8 0 0 8 8 8 1 HEAT-like repeat HEAT PF02985.22 KDO30185.1 - 5.2e-39 128.9 50.9 0.0056 16.8 0.0 22.9 24 0 0 24 24 22 11 HEAT repeat HEAT_EZ PF13513.6 KDO30185.1 - 1.9e-26 92.1 72.6 6.2e-05 23.4 0.1 22.1 19 4 5 24 24 23 11 HEAT-like repeat HEAT_2 PF13646.6 KDO30185.1 - 1.4e-22 79.9 61.2 0.003 17.9 0.3 16.7 11 5 4 17 17 17 8 HEAT repeats Cnd1 PF12717.7 KDO30185.1 - 1.3e-14 54.6 4.0 0.62 10.1 0.0 10.5 11 1 0 12 12 11 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KDO30185.1 - 1.9e-14 53.8 0.0 0.0049 16.5 0.0 8.5 6 3 1 8 8 8 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 KDO30185.1 - 5.8e-10 39.6 0.0 4 8.1 0.0 8.7 7 2 2 9 9 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KDO30185.1 - 2.9e-08 32.7 26.8 0.042 12.4 0.9 9.2 7 2 3 10 10 10 3 Adaptin N terminal region Tti2 PF10521.9 KDO30185.1 - 1.5e-05 24.7 0.0 0.49 9.9 0.0 4.8 4 1 1 5 5 5 2 Tti2 family Cohesin_HEAT PF12765.7 KDO30185.1 - 4.7e-05 23.6 20.8 1.1 9.6 0.0 8.7 10 0 0 10 10 8 2 HEAT repeat associated with sister chromatid cohesion TIP120 PF08623.10 KDO30185.1 - 0.00014 21.7 0.1 0.22 11.3 0.1 5.3 6 0 0 6 6 6 1 TATA-binding protein interacting (TIP20) Ecm29 PF13001.7 KDO30185.1 - 0.014 14.1 0.2 0.26 9.9 0.0 3.2 3 0 0 3 3 3 0 Proteasome stabiliser Dopey_N PF04118.14 KDO30185.1 - 0.026 13.6 0.5 21 4.1 0.0 4.5 5 0 0 5 5 5 0 Dopey, N-terminal NUC173 PF08161.12 KDO30185.1 - 0.071 12.8 1.7 58 3.3 0.0 5.1 5 0 0 5 5 5 0 NUC173 domain DUF3385 PF11865.8 KDO30185.1 - 0.08 12.8 0.0 17 5.3 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) DUF3437 PF11919.8 KDO30185.1 - 0.13 12.2 0.4 39 4.3 0.1 5.0 4 0 0 4 4 3 0 Domain of unknown function (DUF3437) MMS19_N PF14500.6 KDO30185.1 - 0.69 9.4 9.2 30 4.1 0.0 6.0 6 0 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II CENP-B_dimeris PF09026.10 KDO30185.1 - 1.3 9.4 7.0 2.3 8.7 2.0 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 KDO30185.1 - 1.4 9.2 7.1 28 5.0 0.0 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4611) HECT PF00632.25 KDO30186.1 - 3.1e-28 99.2 0.0 1.5e-26 93.6 0.0 2.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_hydro81C PF17652.1 KDO30187.1 - 1.8e-108 362.9 0.0 2.6e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KDO30187.1 - 1.1e-29 103.6 0.1 1.6e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain FAD_binding_4 PF01565.23 KDO30188.1 - 2.4e-16 59.7 0.0 4.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain MATalpha_HMGbox PF04769.12 KDO30191.1 - 0.21 10.9 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Lung_7-TM_R PF06814.13 KDO30191.1 - 2.3 7.4 21.2 3.7 6.7 21.2 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor Na_H_antiporter PF03553.14 KDO30193.1 - 4.5e-50 170.6 4.8 4.5e-50 170.6 4.8 2.4 1 1 1 2 2 2 2 Na+/H+ antiporter family Methyltransf_23 PF13489.6 KDO30194.1 - 0.028 14.3 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MgtE_N PF03448.17 KDO30194.1 - 0.032 14.8 0.3 0.13 12.9 0.1 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Methyltransf_32 PF13679.6 KDO30194.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain KIAA1430 PF13879.6 KDO30195.1 - 8.8e-14 52.1 9.3 3.7e-13 50.1 5.6 2.4 2 0 0 2 2 2 1 KIAA1430 homologue YppG PF14179.6 KDO30195.1 - 2.7 8.7 6.0 0.42 11.3 1.4 2.2 2 1 0 2 2 2 0 YppG-like protein cobW PF02492.19 KDO30196.1 - 1e-53 181.5 0.0 3.1e-53 180.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KDO30196.1 - 1.4e-16 60.2 0.0 8.5e-16 57.7 0.0 2.2 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KDO30196.1 - 0.00047 20.1 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 KDO30196.1 - 0.0092 15.0 0.8 0.72 8.8 0.0 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KDO30196.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO30196.1 - 0.019 15.1 0.1 0.13 12.3 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO30196.1 - 0.02 15.3 0.2 0.096 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 KDO30196.1 - 0.032 14.1 0.5 1.6 8.6 0.1 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 KDO30196.1 - 0.033 13.7 0.1 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KDO30196.1 - 0.048 13.7 0.2 0.091 12.8 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KDO30196.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO30196.1 - 0.073 13.3 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KDO30196.1 - 0.15 12.6 0.1 0.35 11.4 0.1 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KDO30196.1 - 0.18 11.2 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CENP-F_leu_zip PF10473.9 KDO30197.1 - 0.0085 16.1 6.1 0.0085 16.1 6.1 4.9 2 2 3 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 KDO30197.1 - 0.03 15.2 5.6 0.03 15.2 5.6 3.9 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Bcr-Abl_Oligo PF09036.10 KDO30197.1 - 0.16 12.0 1.6 13 5.9 0.1 3.3 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain ABC_tran_CTD PF16326.5 KDO30197.1 - 0.25 11.6 18.1 0.089 13.1 2.1 4.1 3 1 1 4 4 4 0 ABC transporter C-terminal domain GEMIN8 PF15348.6 KDO30197.1 - 0.99 9.7 9.9 0.068 13.5 4.6 1.7 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 DUF4140 PF13600.6 KDO30197.1 - 1.9 9.0 0.0 1.9 9.0 0.0 4.9 3 2 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.11 KDO30197.1 - 2.7 8.3 5.4 74 3.7 2.1 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Hist_deacetyl PF00850.19 KDO30199.1 - 4.6e-64 216.8 0.2 7.3e-64 216.2 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ank_5 PF13857.6 KDO30199.1 - 1.2e-14 54.2 2.0 3.6e-09 36.7 0.1 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30199.1 - 1.7e-11 44.5 2.0 0.00091 19.8 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30199.1 - 2.6e-10 40.6 5.1 2.1e-05 25.0 0.1 4.8 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30199.1 - 1.4e-09 37.3 1.9 0.97 10.2 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KDO30199.1 - 3.6e-07 30.3 6.2 2.5 8.7 0.0 5.7 5 1 0 5 5 5 3 Ankyrin repeat PKS_DE PF18369.1 KDO30199.1 - 0.028 15.0 1.2 0.028 15.0 1.2 2.2 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain TehB PF03848.14 KDO30200.1 - 0.064 12.7 0.1 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Tellurite resistance protein TehB Sec63 PF02889.16 KDO30202.1 - 7.4e-146 484.1 0.1 1.5e-79 266.8 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KDO30202.1 - 2.4e-41 141.4 0.0 1.5e-25 89.9 0.2 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KDO30202.1 - 1.3e-37 128.4 0.5 6.2e-37 126.2 0.1 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 KDO30202.1 - 1.7e-18 67.2 0.0 1.5e-13 51.1 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO30202.1 - 7.3e-10 39.2 0.0 2.3e-07 31.1 0.0 3.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KDO30202.1 - 1.2e-08 35.3 0.1 0.00065 20.0 0.1 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 KDO30202.1 - 0.00017 21.9 2.1 0.33 11.3 0.2 3.3 4 0 0 4 4 3 2 AAA domain AAA_11 PF13086.6 KDO30202.1 - 0.0036 17.1 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KDO30202.1 - 0.0042 16.7 0.0 7.5 6.0 0.0 3.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.21 KDO30202.1 - 0.014 14.8 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KDO30202.1 - 0.017 14.8 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KDO30202.1 - 0.025 14.1 0.0 7.1 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KDO30202.1 - 0.074 13.0 0.0 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 KDO30202.1 - 0.12 11.5 0.1 15 4.6 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein Chisel PF15355.6 KDO30202.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel DUF5586 PF17824.1 KDO30203.1 - 0.00098 18.3 0.1 0.022 13.9 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5586) RIIa PF02197.17 KDO30203.1 - 0.01 15.5 0.1 0.085 12.5 0.0 2.2 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 KDO30203.1 - 0.032 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Dpy-30 motif MFS_1 PF07690.16 KDO30204.1 - 2.2e-32 112.4 31.5 2.2e-32 112.4 31.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO30204.1 - 8.4e-25 87.1 21.4 1.7e-16 59.7 1.8 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO30204.1 - 7.7e-11 41.5 22.1 9.1e-10 38.0 22.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter RRM_1 PF00076.22 KDO30205.1 - 9.1e-17 60.6 0.2 1.5e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO30205.1 - 0.024 14.2 0.1 0.039 13.5 0.1 1.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOP5NT PF08156.13 KDO30205.1 - 0.035 14.5 0.7 0.77 10.2 0.3 2.4 1 1 1 2 2 2 0 NOP5NT (NUC127) domain RRM_3 PF08777.11 KDO30205.1 - 0.04 14.0 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KDO30205.1 - 0.059 13.2 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Abhydrolase_1 PF00561.20 KDO30206.1 - 1.1e-08 35.0 0.2 2.3e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO30206.1 - 7e-06 25.5 0.0 0.0022 17.3 0.0 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO30206.1 - 0.0022 18.7 0.9 0.004 17.8 0.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KDO30206.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein ELP6 PF09807.9 KDO30207.1 - 8.4e-40 136.8 0.1 1.1e-39 136.4 0.1 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 KDO30207.1 - 4.5e-07 29.7 0.0 7.8e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 Elongator subunit Iki1 DUF835 PF05763.12 KDO30207.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Abhydrolase_6 PF12697.7 KDO30208.1 - 0.0011 19.6 1.7 0.0021 18.7 1.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KDO30208.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 KDO30208.1 - 0.03 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KDO30209.1 - 0.013 16.1 4.3 0.036 14.7 4.3 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KDO30209.1 - 0.018 15.2 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Enolase_like_N PF18374.1 KDO30209.1 - 0.085 12.2 0.1 0.26 10.7 0.1 1.8 1 0 0 1 1 1 0 Enolase N-terminal domain-like Palm_thioest PF02089.15 KDO30209.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DNA_ligase_A_M PF01068.21 KDO30210.1 - 1.5e-58 197.8 0.4 2.5e-58 197.1 0.4 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KDO30210.1 - 1.6e-39 136.0 0.1 3.6e-39 134.9 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KDO30210.1 - 4.5e-24 84.9 0.0 1.5e-23 83.2 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KDO30210.1 - 0.00065 19.6 0.1 0.042 13.7 0.1 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Siva PF05458.12 KDO30211.1 - 0.012 15.3 14.4 0.012 15.3 14.4 1.3 1 1 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 KDO30211.1 - 0.23 11.7 8.6 0.26 11.5 8.6 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger WD40 PF00400.32 KDO30212.1 - 5.2e-67 220.1 19.7 1.6e-09 38.2 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30212.1 - 1.1e-22 80.2 3.4 0.00078 19.7 0.3 6.5 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KDO30212.1 - 1.3e-12 48.0 0.1 2.2e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KDO30212.1 - 6.4e-09 35.2 0.2 0.11 11.4 0.0 5.3 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO30212.1 - 3.2e-08 33.7 0.5 0.038 13.9 0.0 4.0 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KDO30212.1 - 9.3e-06 25.4 6.9 2 8.5 0.0 5.0 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KDO30212.1 - 0.00016 20.5 0.9 11 4.6 0.0 4.3 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KDO30212.1 - 0.0014 18.1 0.6 13 5.0 0.0 4.1 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KDO30212.1 - 0.002 16.9 0.2 1.1 8.0 0.0 2.6 2 1 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KDO30212.1 - 0.0067 15.0 0.0 0.61 8.6 0.0 3.0 2 2 1 4 4 4 2 Cytochrome D1 heme domain WD40_like PF17005.5 KDO30212.1 - 0.021 14.2 0.0 1.5 8.1 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain Proteasome_A_N PF10584.9 KDO30212.1 - 0.19 11.5 4.7 26 4.6 0.1 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Bromodomain PF00439.25 KDO30213.1 - 1.9e-14 53.5 0.0 3.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KDO30213.1 - 1.1e-09 38.1 10.6 1.1e-09 38.1 10.6 2.0 2 0 0 2 2 2 1 PHD-finger Cwf_Cwc_15 PF04889.12 KDO30213.1 - 0.0075 16.0 5.1 0.0075 16.0 5.1 3.7 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein zf-4CXXC_R1 PF10497.9 KDO30213.1 - 8.6 6.7 17.4 12 6.2 8.0 2.4 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Abhydrolase_6 PF12697.7 KDO30214.1 - 0.0013 19.4 10.6 0.014 16.1 10.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KDO30214.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Polyoma_coat2 PF00761.20 KDO30214.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein F5_F8_type_C PF00754.25 KDO30216.1 - 1.6e-08 34.7 0.4 2e-08 34.4 0.4 1.1 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 KDO30216.1 - 6.4e-07 29.5 0.0 9.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain Sad1_UNC PF07738.13 KDO30216.1 - 0.018 15.0 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal VWA_2 PF13519.6 KDO30217.1 - 2.7e-14 53.7 1.4 7.4e-14 52.3 0.1 2.5 3 1 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 KDO30217.1 - 0.00075 19.4 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KDO30217.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-C2HC_2 PF13913.6 KDO30218.1 - 3.7e-05 23.5 0.9 3.7e-05 23.5 0.9 3.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type FTA4 PF13093.6 KDO30218.1 - 0.0003 20.7 1.1 0.00035 20.5 1.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 KDO30218.1 - 0.0033 17.9 6.9 0.0046 17.5 6.9 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KDO30218.1 - 0.033 13.8 7.4 0.044 13.4 7.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4164 PF13747.6 KDO30218.1 - 0.035 14.4 7.9 0.06 13.6 7.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) zf-Di19 PF05605.12 KDO30218.1 - 0.044 14.1 2.2 0.092 13.1 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FAM76 PF16046.5 KDO30218.1 - 0.12 11.8 7.3 0.032 13.6 3.4 1.8 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 KDO30218.1 - 0.17 10.8 8.4 0.22 10.4 8.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LINES_C PF14695.6 KDO30218.1 - 0.29 10.6 1.6 14 5.2 0.2 2.6 2 0 0 2 2 2 0 Lines C-terminus PRKG1_interact PF15898.5 KDO30218.1 - 0.36 11.8 6.9 0.98 10.4 6.7 1.8 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CREPT PF16566.5 KDO30218.1 - 0.97 9.6 7.3 1.9 8.6 7.3 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2514 PF10721.9 KDO30218.1 - 1 9.4 11.2 9.2 6.3 11.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) ZapB PF06005.12 KDO30218.1 - 1.1 9.7 10.1 3 8.4 6.2 2.4 1 1 2 3 3 3 0 Cell division protein ZapB NRBF2 PF08961.10 KDO30218.1 - 2.3 7.8 7.0 28 4.2 7.0 2.0 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ADIP PF11559.8 KDO30218.1 - 5.2 7.1 15.9 19 5.3 2.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KDO30218.1 - 10 6.0 10.0 15 5.4 5.8 2.4 1 1 1 2 2 2 0 Septum formation initiator Mannosyl_trans3 PF11051.8 KDO30219.1 - 2.5e-16 59.9 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative AAA PF00004.29 KDO30220.1 - 1.4e-15 57.9 0.0 2.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KDO30220.1 - 1.6e-13 50.8 0.0 1.2e-10 41.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KDO30220.1 - 1.1e-12 48.1 0.0 8.6e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 KDO30220.1 - 6.1e-06 26.3 0.0 3.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KDO30220.1 - 2.8e-05 24.4 1.4 0.37 11.1 0.0 3.7 1 1 3 4 4 4 2 AAA domain DNA_pol3_delta PF06144.13 KDO30220.1 - 3e-05 23.9 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KDO30220.1 - 3.7e-05 24.2 0.0 9.1e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KDO30220.1 - 8.3e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KDO30220.1 - 0.00015 21.8 0.0 0.0046 17.0 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KDO30220.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KDO30220.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KDO30220.1 - 0.00032 20.7 1.4 0.003 17.6 0.1 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KDO30220.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO30220.1 - 0.0011 18.7 0.0 0.0034 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KDO30220.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_assoc_2 PF16193.5 KDO30220.1 - 0.0022 18.3 0.0 0.0067 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA C-terminal domain TniB PF05621.11 KDO30220.1 - 0.0045 16.4 0.1 0.044 13.2 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein AAA_11 PF13086.6 KDO30220.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KDO30220.1 - 0.0089 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KDO30220.1 - 0.016 15.8 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KDO30220.1 - 0.023 14.5 0.1 0.45 10.3 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase MCM PF00493.23 KDO30220.1 - 0.028 13.5 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain IstB_IS21 PF01695.17 KDO30220.1 - 0.038 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 KDO30220.1 - 0.042 14.2 0.0 0.88 9.9 0.0 2.4 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KDO30220.1 - 0.05 13.0 0.1 0.14 11.5 0.1 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KDO30220.1 - 0.061 12.8 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 KDO30220.1 - 0.066 11.9 0.2 0.38 9.4 0.0 2.2 3 0 0 3 3 3 0 SNF2 family N-terminal domain TIP49 PF06068.13 KDO30220.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KDO30220.1 - 0.13 12.6 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 KDO30220.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Acid_PPase PF12689.7 KDO30221.1 - 1.7e-51 174.4 0.0 2e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Lung_7-TM_R PF06814.13 KDO30222.1 - 0.68 9.1 9.9 0.27 10.5 6.2 2.1 2 1 0 2 2 2 0 Lung seven transmembrane receptor C2 PF00168.30 KDO30223.1 - 5e-11 42.8 0.0 1.1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain PHF5 PF03660.14 KDO30223.1 - 0.81 9.9 5.1 2.2 8.5 5.1 1.7 1 0 0 1 1 1 0 PHF5-like protein DZR PF12773.7 KDO30223.1 - 1.4 9.0 10.3 4.2 7.5 10.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon YabA PF06156.13 KDO30223.1 - 5.5 7.7 11.7 1.8 9.3 3.5 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Band_7 PF01145.25 KDO30224.1 - 8.6e-17 61.7 4.6 6.8e-16 58.8 0.0 2.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family C_GCAxxG_C_C PF09719.10 KDO30224.1 - 0.11 12.8 0.9 0.21 11.9 0.9 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Band_7_1 PF13421.6 KDO30224.1 - 0.18 11.5 3.7 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 SPFH domain-Band 7 family DUF1439 PF07273.12 KDO30224.1 - 0.19 11.5 7.5 0.62 9.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1439) Band_7 PF01145.25 KDO30225.1 - 3.4e-25 89.1 0.0 3.4e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KDO30225.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family RTP1_C1 PF10363.9 KDO30225.1 - 0.019 15.2 0.0 8.2 6.6 0.0 2.7 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3629 PF12302.8 KDO30225.1 - 0.03 13.7 6.8 0.038 13.4 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3629) Acyl_transf_3 PF01757.22 KDO30226.1 - 2.6e-20 72.8 30.6 2.6e-20 72.8 30.6 2.0 1 1 1 2 2 2 1 Acyltransferase family ABC_membrane PF00664.23 KDO30227.1 - 6.5e-14 52.2 22.3 5.5e-09 36.1 0.9 3.2 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO30227.1 - 1.4e-11 45.0 0.0 3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KDO30227.1 - 0.0085 16.5 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KDO30227.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KDO30227.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Melittin PF01372.17 KDO30227.1 - 0.18 11.8 0.5 0.84 9.7 0.2 2.4 2 0 0 2 2 2 0 Melittin DUF1180 PF06679.12 KDO30227.1 - 9.1 6.7 6.6 0.39 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PG_binding_1 PF01471.18 KDO30228.1 - 0.21 11.8 4.3 0.079 13.2 1.3 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain FPN1 PF06963.12 KDO30229.1 - 4.6e-85 285.8 33.5 3e-48 164.5 10.9 2.2 1 1 1 2 2 2 2 Ferroportin1 (FPN1) GATase PF00117.28 KDO30230.1 - 2.8e-48 164.2 0.0 3.1e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KDO30230.1 - 1e-05 25.4 1.0 8.1e-05 22.5 1.0 1.9 1 1 0 1 1 1 1 Peptidase C26 RCC1 PF00415.18 KDO30231.1 - 4.3e-43 145.7 28.1 2e-12 47.5 0.1 9.5 10 0 0 10 10 10 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO30231.1 - 4.4e-27 93.3 44.4 1.6e-06 27.8 1.4 8.3 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_1 PF00036.32 KDO30231.1 - 5.3e-13 47.5 8.9 1.9e-05 23.8 0.6 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO30231.1 - 1.4e-11 43.3 8.5 0.0016 18.2 0.4 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KDO30231.1 - 3.3e-11 43.5 2.0 5.1e-07 30.0 0.4 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO30231.1 - 2.2e-08 33.2 5.7 0.0027 17.1 0.2 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO30231.1 - 1.2e-07 31.5 5.9 0.0078 16.0 0.3 3.6 2 1 1 3 3 3 3 EF-hand domain pair F5_F8_type_C PF00754.25 KDO30231.1 - 0.096 12.8 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 F5/8 type C domain Hira PF07569.11 KDO30231.1 - 0.21 11.3 1.4 14 5.3 0.0 4.1 5 0 0 5 5 5 0 TUP1-like enhancer of split GAF PF01590.26 KDO30232.1 - 0.00053 20.6 0.0 0.00093 19.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO30232.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 GAF domain C1_2 PF03107.16 KDO30232.1 - 0.15 12.4 8.4 0.2 12.0 7.1 1.9 2 0 0 2 2 2 0 C1 domain Siva PF05458.12 KDO30232.1 - 0.2 11.4 9.9 0.31 10.7 9.9 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 KDO30232.1 - 0.21 11.8 10.2 0.4 10.9 10.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger C6_DPF PF10170.9 KDO30232.1 - 0.28 11.6 8.1 0.7 10.3 8.1 1.6 1 0 0 1 1 1 0 Cysteine-rich domain FYVE PF01363.21 KDO30232.1 - 1.6 8.9 17.9 4.6 7.5 17.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger GAF PF01590.26 KDO30233.1 - 2.2e-07 31.6 0.2 3.9e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 KDO30233.1 - 1.5e-06 28.2 9.7 2.5e-06 27.5 9.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger GAF_3 PF13492.6 KDO30233.1 - 1.9e-06 28.2 0.8 4.1e-06 27.2 0.8 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO30233.1 - 1.4e-05 25.4 0.2 2.6e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO30233.1 - 0.076 13.2 9.8 0.2 11.9 9.8 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Ribosomal_L37ae PF01780.19 KDO30234.1 - 3.3e-40 136.0 7.3 4.2e-40 135.7 7.3 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KDO30234.1 - 0.18 11.8 6.3 0.39 10.7 6.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Guanylate_cyc PF00211.20 KDO30235.1 - 8.1e-23 81.0 0.0 2e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.29 KDO30235.1 - 6.2e-07 29.9 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 PH domain AAA_16 PF13191.6 KDO30235.1 - 3.8e-06 27.4 0.0 2.6e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain FYVE PF01363.21 KDO30235.1 - 1.2e-05 25.4 13.9 1.2e-05 25.4 13.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger DnaJ PF00226.31 KDO30237.1 - 5.9e-20 71.2 0.3 5.9e-20 71.2 0.3 2.4 3 0 0 3 3 3 1 DnaJ domain Death PF00531.22 KDO30237.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Death domain BLACT_WH PF17778.1 KDO30238.1 - 0.13 12.3 1.4 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Ank_2 PF12796.7 KDO30239.1 - 1.9e-41 140.5 6.1 2.3e-14 53.8 0.0 5.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30239.1 - 8.6e-33 112.3 7.5 4e-12 46.4 0.1 7.5 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30239.1 - 3.5e-27 91.4 10.7 9.1e-05 22.6 0.0 8.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KDO30239.1 - 1.6e-25 88.8 13.0 2.7e-06 27.6 0.0 7.5 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO30239.1 - 1.4e-24 85.4 21.3 3.5e-05 24.1 0.2 8.7 9 0 0 9 9 9 5 Ankyrin repeat TIR_2 PF13676.6 KDO30239.1 - 3.4e-17 63.2 0.0 4.9e-08 33.6 0.0 3.3 3 0 0 3 3 3 2 TIR domain DUF815 PF05673.13 KDO30239.1 - 0.23 10.6 0.6 18 4.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) LRR_9 PF14580.6 KDO30240.1 - 4.5e-13 49.1 0.0 2.5e-09 36.9 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KDO30240.1 - 8.7e-11 41.9 0.0 3.3e-06 27.4 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO30240.1 - 0.0033 17.2 6.9 0.073 12.8 0.0 3.5 3 1 0 3 3 3 2 Leucine rich repeat Sterol_MT_C PF08498.10 KDO30241.1 - 3.5e-27 94.5 0.2 8.3e-27 93.3 0.2 1.7 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KDO30241.1 - 4.3e-21 75.4 0.0 1.2e-20 74.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO30241.1 - 2.9e-18 66.3 0.0 7.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO30241.1 - 1.8e-17 63.6 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO30241.1 - 5.1e-16 58.8 0.0 7.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KDO30241.1 - 1.3e-14 54.4 0.0 2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO30241.1 - 6.3e-11 42.0 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KDO30241.1 - 2.6e-09 37.7 0.0 9.5e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KDO30241.1 - 0.00089 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO30241.1 - 0.0016 18.1 0.0 0.0038 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KDO30241.1 - 0.0028 17.3 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PRE_C2HC PF07530.11 KDO30241.1 - 0.14 12.3 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Associated with zinc fingers UPF0020 PF01170.18 KDO30241.1 - 0.15 11.7 0.0 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 NNMT_PNMT_TEMT PF01234.17 KDO30241.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Tetraspanin PF00335.20 KDO30241.1 - 0.49 10.1 5.0 1.1 8.9 5.0 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF3792 PF12670.7 KDO30241.1 - 4.1 7.6 11.3 0.17 12.1 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) ABC_tran PF00005.27 KDO30242.1 - 3.7e-51 173.2 0.0 4.1e-30 105.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO30242.1 - 4.7e-51 174.0 18.3 6.4e-26 91.6 0.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 KDO30242.1 - 6.2e-06 26.3 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO30242.1 - 3.9e-05 23.3 1.4 0.11 12.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KDO30242.1 - 5.3e-05 22.8 0.7 0.94 8.9 0.0 4.0 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO30242.1 - 0.00015 22.1 5.0 0.2 12.0 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.23 KDO30242.1 - 0.00078 19.5 1.2 0.054 13.6 0.5 2.3 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KDO30242.1 - 0.0012 18.7 0.3 1.8 8.4 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KDO30242.1 - 0.0014 18.9 0.2 0.33 11.2 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KDO30242.1 - 0.0027 17.5 6.4 1.1 9.0 0.0 3.8 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO30242.1 - 0.0033 17.9 1.2 1.5 9.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KDO30242.1 - 0.011 14.9 0.1 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KDO30242.1 - 0.019 14.7 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO30242.1 - 0.022 14.5 1.1 1.5 8.5 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO30242.1 - 0.023 14.8 2.7 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 KDO30242.1 - 0.06 13.1 0.6 7.3 6.3 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 KDO30242.1 - 0.061 13.6 0.1 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KDO30242.1 - 0.069 13.7 0.0 4 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO30242.1 - 0.082 12.5 0.2 4.2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO30242.1 - 0.11 11.8 1.7 7.8 5.8 0.6 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KDO30242.1 - 0.15 12.4 0.2 21 5.5 0.0 2.6 3 0 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.12 KDO30242.1 - 0.19 11.0 0.4 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin MFS_2 PF13347.6 KDO30244.1 - 1.2e-11 43.8 21.8 1.7e-11 43.4 10.1 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_2 PF13347.6 KDO30245.1 - 8.7e-12 44.3 30.9 1e-10 40.8 16.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KDO30245.1 - 2.6e-09 36.5 38.6 8e-07 28.3 17.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CmlA_N PF18456.1 KDO30246.1 - 0.045 13.0 0.4 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain DUF3384 PF11864.8 KDO30246.1 - 0.12 11.3 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) HSP20 PF00011.21 KDO30246.1 - 0.22 11.7 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Telomere_reg-2 PF10193.9 KDO30247.1 - 0.056 13.9 0.4 0.62 10.5 0.0 2.9 2 0 0 2 2 2 0 Telomere length regulation protein Methyltransf_16 PF10294.9 KDO30248.1 - 6.5e-36 123.7 0.0 1.2e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO30248.1 - 9.7e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_12 PF13424.6 KDO30248.1 - 0.00073 19.8 10.7 0.00081 19.6 6.8 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30248.1 - 0.0012 18.8 6.3 1.3 9.4 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat MTS PF05175.14 KDO30248.1 - 0.0017 17.9 0.3 0.0037 16.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TPR_1 PF00515.28 KDO30248.1 - 0.015 15.1 5.6 2.2 8.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 KDO30248.1 - 0.12 10.7 0.2 0.61 8.4 0.5 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal TPR_11 PF13414.6 KDO30248.1 - 1.3 8.8 6.6 0.34 10.6 0.3 2.9 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 KDO30248.1 - 2 9.1 16.3 0.18 12.5 2.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TTL PF03133.15 KDO30249.1 - 2.7e-63 213.8 0.0 4.1e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO30249.1 - 1.2e-08 34.5 0.1 1.6e-06 27.6 0.0 2.9 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO30249.1 - 0.035 13.3 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp R2K_2 PF18299.1 KDO30249.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 LicD PF04991.13 KDO30250.1 - 0.12 12.5 0.8 0.2 11.7 0.8 1.2 1 0 0 1 1 1 0 LicD family Tme5_EGF_like PF09064.10 KDO30250.1 - 1.8 8.6 4.8 2.8 7.9 0.5 2.5 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like APH PF01636.23 KDO30253.1 - 1e-44 153.3 0.0 2e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KDO30253.1 - 1.4e-32 113.0 5.8 2.5e-32 112.2 5.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KDO30253.1 - 2.7e-18 66.0 0.0 4.9e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KDO30253.1 - 3.7e-10 40.2 4.8 3.7e-10 40.2 4.8 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KDO30253.1 - 3.9e-09 37.2 0.0 1e-08 35.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Choline_kinase PF01633.20 KDO30253.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KDO30253.1 - 0.0067 16.0 0.0 1.3 8.5 0.0 2.5 3 0 0 3 3 3 1 RIO1 family EcKinase PF02958.20 KDO30253.1 - 0.049 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 KDO30253.1 - 0.097 12.0 0.0 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_transpo PF04515.12 KDO30254.1 - 4.8e-76 256.0 22.5 4.8e-76 256.0 22.5 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Choline_transpo PF04515.12 KDO30255.1 - 8.2e-54 183.0 29.2 8.2e-54 183.0 29.2 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter Chromate_transp PF02417.15 KDO30256.1 - 7e-62 208.2 38.8 2.7e-35 121.8 20.0 2.2 2 0 0 2 2 2 2 Chromate transporter DUF997 PF06196.12 KDO30256.1 - 4.5 7.3 7.1 19 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Ank_2 PF12796.7 KDO30258.1 - 6.9e-17 61.8 0.5 5.2e-05 23.7 0.0 4.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30258.1 - 2.3e-12 47.2 6.1 0.0021 18.6 0.9 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO30258.1 - 8.1e-10 38.8 12.1 0.016 15.5 0.1 7.0 7 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30258.1 - 5.7e-08 32.4 8.3 1.2 9.9 0.0 8.4 9 0 0 9 9 9 2 Ankyrin repeat Ad_Cy_reg PF16701.5 KDO30258.1 - 0.065 13.0 0.0 11 5.8 0.0 3.0 2 1 0 3 3 3 0 Adenylate cyclase regulatory domain Ank PF00023.30 KDO30258.1 - 0.11 13.0 2.1 60 4.3 0.0 5.2 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KDO30259.1 - 0.12 13.0 0.0 0.39 11.3 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KDO30260.1 - 4.4e-19 68.8 16.9 1.8e-06 28.4 0.1 5.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30260.1 - 7e-16 58.4 11.5 0.0001 22.8 0.1 5.9 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO30260.1 - 9.7e-14 51.3 12.0 0.051 13.9 0.0 8.0 3 2 5 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30260.1 - 2.7e-07 30.3 13.1 1.1 10.0 0.0 8.4 6 2 3 9 9 9 2 Ankyrin repeat Ank PF00023.30 KDO30260.1 - 0.0049 17.3 6.4 36 5.0 0.2 6.3 4 2 1 5 5 5 0 Ankyrin repeat Ad_Cy_reg PF16701.5 KDO30260.1 - 0.056 13.2 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain DUF4269 PF14091.6 KDO30260.1 - 0.13 12.5 0.0 4.5 7.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4269) Abhydrolase_6 PF12697.7 KDO30261.1 - 7.8e-17 62.6 1.1 1.1e-16 62.1 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 KDO30261.1 - 1e-15 57.6 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 KDO30261.1 - 7.7e-14 51.5 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO30261.1 - 3.5e-12 46.5 0.1 3.4e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KDO30261.1 - 8.4e-06 25.7 0.4 0.01 15.7 0.1 2.2 2 0 0 2 2 2 2 Serine hydrolase Thioesterase PF00975.20 KDO30261.1 - 0.0026 17.9 0.2 0.004 17.3 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KDO30261.1 - 0.01 15.7 0.6 0.02 14.7 0.6 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.14 KDO30261.1 - 0.023 13.4 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.13 KDO30261.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KDO30261.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF1057 PF06342.12 KDO30262.1 - 2e-20 73.0 0.0 3.5e-20 72.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 KDO30262.1 - 9.5e-18 64.8 0.3 6.4e-14 52.2 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO30262.1 - 2.2e-15 57.9 7.8 3e-15 57.4 7.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO30262.1 - 8.1e-12 44.9 0.4 1.7e-11 43.9 0.4 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KDO30262.1 - 4.8e-06 26.9 0.1 9.9e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KDO30262.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 KDO30263.1 - 5.4e-19 68.3 0.0 7.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 KDO30263.1 - 3.2e-14 54.1 3.5 4.2e-14 53.7 3.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO30263.1 - 2.1e-13 50.5 0.1 4.5e-13 49.4 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO30263.1 - 2.4e-12 46.6 0.9 7.5e-12 45.0 0.9 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KDO30263.1 - 5.2e-07 30.0 0.1 7.6e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KDO30263.1 - 0.066 13.0 0.3 0.099 12.5 0.3 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KDO30263.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 KDO30263.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) EHN PF06441.12 KDO30263.1 - 0.18 12.2 0.1 0.3 11.5 0.1 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Aminotran_3 PF00202.21 KDO30264.1 - 5.9e-54 183.3 0.0 2.5e-53 181.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 KDO30264.1 - 1.3e-21 77.3 0.0 4.7e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain Peripla_BP_4 PF13407.6 KDO30264.1 - 0.008 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain Aminotran_1_2 PF00155.21 KDO30264.1 - 0.088 12.0 0.0 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II DUF1057 PF06342.12 KDO30265.1 - 2.4e-26 92.5 0.0 3.3e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 KDO30265.1 - 9.4e-15 54.5 0.2 1.6e-14 53.8 0.2 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO30265.1 - 1.6e-13 51.8 4.4 2.5e-13 51.2 4.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO30265.1 - 1.8e-12 47.5 0.2 2.6e-12 46.9 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KDO30265.1 - 0.00034 20.8 0.1 0.00059 20.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KDO30265.1 - 0.00045 20.0 0.1 0.011 15.5 0.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KDO30265.1 - 0.072 12.7 0.0 0.09 12.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 KDO30266.1 - 5.9e-20 71.5 0.0 7.5e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 KDO30266.1 - 1.7e-16 61.5 2.2 2.4e-16 61.0 2.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO30266.1 - 2e-16 60.0 0.1 6.5e-16 58.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO30266.1 - 4.3e-14 52.8 0.0 6.3e-12 45.7 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KDO30266.1 - 3.1e-08 34.0 0.0 4.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 KDO30266.1 - 0.00059 19.7 0.0 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 KDO30266.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KDO30266.1 - 0.004 16.9 0.1 0.1 12.3 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein EHN PF06441.12 KDO30266.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF676 PF05057.14 KDO30266.1 - 0.038 13.5 0.0 0.096 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.13 KDO30266.1 - 0.063 11.8 0.0 0.091 11.2 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 KDO30266.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ndr PF03096.14 KDO30266.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF2974 PF11187.8 KDO30266.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CPSF_A PF03178.15 KDO30267.1 - 2.3e-62 211.2 0.0 6.2e-62 209.8 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KDO30267.1 - 7.3e-31 107.3 0.0 2e-30 105.9 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Iwr1 PF08574.10 KDO30269.1 - 1.1e-08 35.9 16.0 1.1e-08 35.9 16.0 3.0 2 1 0 2 2 2 1 Transcription factor Iwr1 Ank_2 PF12796.7 KDO30269.1 - 0.00023 21.7 0.2 0.00044 20.8 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30269.1 - 0.014 15.9 0.2 0.039 14.6 0.2 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30269.1 - 0.17 12.6 0.1 0.38 11.5 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat eRF1_1 PF03463.15 KDO30272.1 - 1.1e-45 154.8 0.1 2.1e-45 153.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KDO30272.1 - 1.3e-29 103.2 0.1 2.2e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KDO30272.1 - 1.7e-21 76.8 0.0 3.7e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 bZIP_1 PF00170.21 KDO30273.1 - 5.8e-06 26.3 6.3 5.8e-06 26.3 6.3 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KDO30273.1 - 0.0017 18.4 5.0 0.0017 18.4 5.0 2.4 2 0 0 2 2 2 1 Basic region leucine zipper PikAIV_N PF18605.1 KDO30273.1 - 0.036 13.6 0.4 0.096 12.3 0.4 1.8 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TSC22 PF01166.18 KDO30273.1 - 0.67 10.3 8.0 12 6.3 0.2 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family TPR_19 PF14559.6 KDO30274.1 - 0.0024 18.4 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30274.1 - 0.027 14.7 0.2 3 8.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 KDO30275.1 - 1.4 7.4 15.7 0.095 11.3 7.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) A_deamin PF02137.18 KDO30276.1 - 5e-56 190.5 0.1 6.9e-56 190.1 0.1 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Porph_ging PF09697.10 KDO30276.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) TMEM65 PF10507.9 KDO30277.1 - 3.3e-46 155.7 3.8 6.6e-46 154.7 3.8 1.5 1 0 0 1 1 1 1 Transmembrane protein 65 Anoctamin PF04547.12 KDO30278.1 - 0.00012 21.1 10.5 0.00052 19.0 10.5 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.13 KDO30278.1 - 0.00063 20.3 1.3 0.001 19.6 0.4 1.9 2 0 0 2 2 2 1 TMC domain Phage_connect_1 PF05135.13 KDO30278.1 - 0.18 12.3 0.3 7.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Jnk-SapK_ap_N PF09744.9 KDO30278.1 - 0.2 11.9 4.7 0.5 10.6 3.9 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 KDO30278.1 - 0.44 11.2 1.4 0.97 10.1 1.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Sipho_Gp157 PF05565.11 KDO30278.1 - 2 8.4 6.7 0.18 11.8 1.7 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 CRAL_TRIO PF00650.20 KDO30279.1 - 3.7e-34 117.7 0.0 5.7e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 KDO30279.1 - 9.3e-05 22.9 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 KDO30279.1 - 0.037 14.2 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain AMNp_N PF10423.9 KDO30279.1 - 0.16 11.6 0.0 0.72 9.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus adh_short PF00106.25 KDO30280.1 - 4.4e-37 127.4 0.2 6.9e-37 126.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO30280.1 - 1.2e-30 106.8 0.7 1.8e-30 106.2 0.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO30280.1 - 5.2e-17 62.3 0.6 1.4e-16 61.0 0.6 1.7 1 1 0 1 1 1 1 KR domain SCP2 PF02036.17 KDO30280.1 - 7.5e-11 42.4 0.0 1.7e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 SCP-2 sterol transfer family Epimerase PF01370.21 KDO30280.1 - 1.6e-05 24.5 0.1 3e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO30280.1 - 0.0081 16.1 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAAA-beta PF15508.6 KDO30280.1 - 0.12 12.7 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1191 PF06697.12 KDO30280.1 - 0.15 11.8 0.1 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Pkinase PF00069.25 KDO30281.1 - 3.7e-58 197.0 0.0 9.5e-58 195.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30281.1 - 1.2e-33 116.5 0.0 1.8e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO30281.1 - 1.5e-11 44.7 0.1 5.2e-11 43.0 0.1 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO30281.1 - 0.0012 19.3 0.8 0.0032 17.9 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.6 KDO30281.1 - 0.0018 17.7 0.0 0.005 16.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO30281.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KDO30281.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 IQ PF00612.27 KDO30282.1 - 1.6e-07 30.5 19.6 0.0013 18.3 2.1 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif MOR2-PAG1_N PF14222.6 KDO30282.1 - 0.15 11.0 1.0 0.37 9.7 0.1 1.9 2 0 0 2 2 2 0 Cell morphogenesis N-terminal SUIM_assoc PF16619.5 KDO30282.1 - 0.48 10.5 8.2 2.4 8.3 8.2 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FYVE PF01363.21 KDO30283.1 - 4.5e-11 42.7 13.7 9.7e-11 41.7 13.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO30283.1 - 0.11 12.7 9.9 0.24 11.6 9.9 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger DUP PF00674.18 KDO30283.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 DUP family OPA3 PF07047.12 KDO30284.1 - 2e-31 108.4 0.2 3.5e-31 107.6 0.2 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF1043 PF06295.12 KDO30284.1 - 0.016 15.2 5.6 0.016 15.2 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ADIP PF11559.8 KDO30284.1 - 0.021 14.9 10.4 0.041 14.0 10.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KDO30284.1 - 0.031 14.6 0.5 0.093 13.1 0.5 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family FlaC_arch PF05377.11 KDO30284.1 - 0.14 12.6 1.1 0.28 11.6 0.6 1.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KDO30284.1 - 0.88 9.4 11.8 1.1 9.0 0.2 2.9 2 1 1 3 3 3 0 Septum formation initiator tRNA-synt_1b PF00579.25 KDO30285.1 - 6.6e-71 239.0 0.0 8.7e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Herpes_LMP1 PF05297.11 KDO30287.1 - 0.2 10.8 2.5 0.21 10.8 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ank_4 PF13637.6 KDO30288.1 - 0.00024 21.6 0.0 0.0016 19.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30288.1 - 0.00068 20.2 0.1 0.0023 18.5 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO30288.1 - 0.0031 17.9 0.2 2.6 8.9 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KDO30288.1 - 0.01 16.2 0.7 3.2 8.4 0.1 3.3 2 0 0 2 2 2 0 Ankyrin repeat Pex24p PF06398.11 KDO30288.1 - 0.017 14.1 0.0 0.017 14.1 0.0 2.7 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin HOOK PF05622.12 KDO30288.1 - 0.02 13.1 0.1 0.028 12.6 0.1 1.1 1 0 0 1 1 1 0 HOOK protein DUF3403 PF11883.8 KDO30288.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) Afaf PF15339.6 KDO30288.1 - 0.56 9.9 0.0 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 Acrosome formation-associated factor Spidroin_N PF16763.5 KDO30288.1 - 2.2 8.3 4.6 13 5.8 1.4 2.5 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Peptidase_M75 PF09375.10 KDO30289.1 - 0.015 14.8 3.7 0.038 13.5 3.7 1.8 1 1 0 1 1 1 0 Imelysin HOOK PF05622.12 KDO30289.1 - 0.017 13.3 0.1 0.021 13.0 0.1 1.1 1 0 0 1 1 1 0 HOOK protein Afaf PF15339.6 KDO30289.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Acrosome formation-associated factor HAGH_C PF16123.5 KDO30289.1 - 0.063 13.8 0.4 6.6 7.3 0.1 2.3 2 1 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus CLZ PF16526.5 KDO30289.1 - 0.065 13.6 0.7 0.13 12.6 0.3 1.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels N6-adenineMlase PF10237.9 KDO30290.1 - 1.4e-41 142.0 0.9 1.7e-41 141.7 0.9 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KDO30290.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-HC2 PF13490.6 KDO30290.1 - 0.24 11.7 0.3 0.43 10.9 0.3 1.4 1 0 0 1 1 1 0 Putative zinc-finger BT1 PF03092.16 KDO30291.1 - 7.5e-19 67.3 11.3 9.3e-11 40.6 0.4 3.3 3 0 0 3 3 3 3 BT1 family ABC2_membrane PF01061.24 KDO30293.1 - 2.2e-68 229.8 74.1 5.8e-40 136.9 27.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO30293.1 - 1.9e-21 77.0 0.0 2.7e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30293.1 - 3.7e-05 23.7 0.1 0.037 13.9 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 KDO30293.1 - 0.00013 21.6 1.5 0.00013 21.6 1.5 4.6 5 0 0 5 5 3 2 Plant PDR ABC transporter associated PDR_CDR PF06422.12 KDO30293.1 - 0.0011 18.8 12.7 0.02 14.8 0.1 3.6 3 0 0 3 3 2 2 CDR ABC transporter RsgA_GTPase PF03193.16 KDO30293.1 - 0.0063 16.4 0.4 0.013 15.4 0.4 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO30293.1 - 0.0069 16.1 0.9 0.019 14.7 0.9 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KDO30293.1 - 0.012 14.8 60.6 0.01 14.9 29.3 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_16 PF13191.6 KDO30293.1 - 0.043 14.2 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KDO30293.1 - 0.19 11.2 0.2 0.52 9.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KDO30293.1 - 0.42 10.0 0.7 32 3.9 0.2 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO30293.1 - 0.58 10.6 1.3 1.1 9.8 1.3 1.3 1 0 0 1 1 1 0 AAA domain DFP PF04127.15 KDO30294.1 - 7e-19 68.4 0.1 1.9e-10 40.9 0.0 2.6 2 1 1 3 3 3 2 DNA / pantothenate metabolism flavoprotein tRNA-synt_2 PF00152.20 KDO30295.1 - 3.1e-74 249.9 0.0 4e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 KDO30295.1 - 4e-09 36.5 0.4 1e-08 35.2 0.4 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 KDO30295.1 - 4.9e-05 23.2 0.1 8.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KDO30295.1 - 0.0038 16.7 0.2 0.93 8.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF2817 PF10994.8 KDO30296.1 - 7.1e-77 259.1 0.0 8.2e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Acyltransferase PF01553.21 KDO30297.1 - 0.00019 21.1 0.1 0.0011 18.6 0.2 2.1 2 1 0 2 2 2 1 Acyltransferase DAGAT PF03982.13 KDO30297.1 - 0.0002 20.4 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Lip_A_acyltrans PF03279.13 KDO30297.1 - 0.072 12.3 0.0 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase CemA PF03040.14 KDO30297.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 CemA family BolA PF01722.18 KDO30298.1 - 2e-31 108.1 0.2 2.5e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein DAGAT PF03982.13 KDO30299.1 - 6.9e-07 28.5 0.0 1.5e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol acyltransferase CemA PF03040.14 KDO30299.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 CemA family Bax1-I PF01027.20 KDO30300.1 - 2.4e-30 105.9 26.4 2.9e-30 105.7 26.4 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 KDO30300.1 - 1.8 6.7 19.2 2.3 6.4 19.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_28 PF13521.6 KDO30301.1 - 9.4e-11 42.2 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO30301.1 - 1.4e-10 41.8 0.0 2.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KDO30301.1 - 9.9e-07 28.8 0.3 1.8e-06 27.9 0.3 1.4 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 KDO30301.1 - 0.00014 22.0 0.0 0.00045 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KDO30301.1 - 0.033 13.4 0.6 2.2 7.4 0.0 2.5 2 1 1 3 3 3 0 NB-ARC domain Thymidylate_kin PF02223.17 KDO30301.1 - 0.067 12.9 0.1 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 KDO30301.1 - 0.068 13.4 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO30301.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lon_C PF05362.13 KDO30302.1 - 1.5e-75 253.2 0.1 3e-75 252.3 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KDO30302.1 - 6.4e-37 127.4 0.1 6.4e-37 127.4 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KDO30302.1 - 1.1e-16 61.4 0.5 1e-15 58.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KDO30302.1 - 1.5e-07 31.3 0.0 3.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KDO30302.1 - 0.00011 22.6 0.5 0.003 18.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KDO30302.1 - 0.00019 21.7 4.6 0.31 11.3 0.1 4.5 3 1 1 4 4 4 1 AAA domain AAA_2 PF07724.14 KDO30302.1 - 0.001 19.2 0.1 0.011 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KDO30302.1 - 0.0012 17.9 0.0 0.003 16.5 0.0 1.6 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KDO30302.1 - 0.0012 18.6 0.0 0.0043 16.8 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KDO30302.1 - 0.011 15.6 0.0 0.041 13.8 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KDO30302.1 - 0.014 15.4 0.2 0.32 11.1 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KDO30302.1 - 0.018 15.0 0.0 0.093 12.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KDO30302.1 - 0.022 15.3 1.8 0.049 14.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain F-box-like_2 PF13013.6 KDO30302.1 - 0.19 11.7 0.6 0.72 9.9 0.0 2.2 3 0 0 3 3 2 0 F-box-like domain Exonuc_VII_L PF02601.15 KDO30302.1 - 0.3 10.6 4.3 0.52 9.8 4.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit 5_3_exonuc PF01367.20 KDO30302.1 - 0.5 11.0 2.4 1.5 9.5 2.4 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF1493 PF07377.12 KDO30302.1 - 0.6 10.6 5.0 4.2 7.9 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1493) DUF445 PF04286.12 KDO30302.1 - 1.7 8.4 7.8 1.2 8.8 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF445) ABC2_membrane PF01061.24 KDO30303.1 - 1.1e-71 240.6 62.1 2.3e-38 131.7 30.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO30303.1 - 1.7e-32 112.8 0.0 9.4e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30303.1 - 1.3e-07 31.7 0.9 0.037 13.8 0.0 3.4 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 KDO30303.1 - 1.6e-07 30.9 4.1 1e-06 28.3 0.7 4.2 4 0 0 4 4 3 2 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 KDO30303.1 - 3.3e-06 27.1 2.0 0.014 15.3 0.4 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO30303.1 - 6e-06 25.9 5.5 0.024 14.4 0.8 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO30303.1 - 1.1e-05 25.9 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain PDR_CDR PF06422.12 KDO30303.1 - 2.1e-05 24.3 0.2 2.1e-05 24.3 0.2 3.5 4 0 0 4 4 3 1 CDR ABC transporter Zeta_toxin PF06414.12 KDO30303.1 - 2.9e-05 23.5 0.1 0.0068 15.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KDO30303.1 - 0.00026 21.3 0.2 0.91 9.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 KDO30303.1 - 0.0008 18.9 0.6 1.4 8.3 0.1 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KDO30303.1 - 0.0016 19.0 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO30303.1 - 0.0033 17.9 0.9 4.5 7.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO30303.1 - 0.0037 17.0 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KDO30303.1 - 0.0057 15.8 49.6 0.11 11.5 28.8 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein MMR_HSR1 PF01926.23 KDO30303.1 - 0.006 16.7 0.5 1.5 8.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KDO30303.1 - 0.0073 15.9 2.9 0.95 9.0 0.3 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KDO30303.1 - 0.014 15.4 0.4 0.65 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KDO30303.1 - 0.015 15.5 0.8 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KDO30303.1 - 0.031 14.8 3.3 1.1 9.7 1.1 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO30303.1 - 0.06 12.5 0.4 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 KDO30303.1 - 0.063 13.2 0.5 0.9 9.4 0.1 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KDO30303.1 - 0.066 13.6 1.1 6 7.3 0.1 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KDO30303.1 - 0.071 13.3 0.1 9.2 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KDO30303.1 - 0.1 12.3 1.4 14 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KDO30303.1 - 0.11 12.2 0.7 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KDO30303.1 - 0.12 12.7 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KDO30303.1 - 0.18 11.1 1.8 4.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region cobW PF02492.19 KDO30303.1 - 0.23 11.1 3.2 1.5 8.3 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO30303.1 - 0.26 11.2 5.3 6 6.8 0.3 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KDO30303.1 - 0.31 10.8 2.6 5.5 6.7 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KDO30303.1 - 2.5 8.1 5.0 24 4.9 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 KDO30304.1 - 1.7e-50 171.4 52.8 6e-33 114.0 22.5 3.1 2 1 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO30304.1 - 5.3e-32 111.2 0.0 1.1e-15 58.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30304.1 - 1.3e-07 31.8 0.9 0.041 13.7 0.0 3.4 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 KDO30304.1 - 1.6e-07 31.0 8.9 0.00032 20.4 1.6 3.8 3 0 0 3 3 3 2 Plant PDR ABC transporter associated PDR_CDR PF06422.12 KDO30304.1 - 3.1e-07 30.2 2.6 4.9e-06 26.3 0.0 3.1 2 1 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 KDO30304.1 - 2.3e-06 27.6 1.6 0.013 15.4 0.3 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO30304.1 - 5.1e-06 26.1 5.3 0.018 14.7 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO30304.1 - 9.3e-06 26.1 0.1 0.14 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KDO30304.1 - 4.9e-05 22.7 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KDO30304.1 - 0.00035 20.9 0.2 0.83 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KDO30304.1 - 0.00067 19.2 0.5 1.4 8.3 0.1 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KDO30304.1 - 0.0013 19.3 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KDO30304.1 - 0.0027 18.1 1.0 3.8 7.9 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO30304.1 - 0.0027 17.4 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO30304.1 - 0.0028 17.3 1.3 0.8 9.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KDO30304.1 - 0.006 16.7 0.6 1.5 9.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KDO30304.1 - 0.0076 16.5 0.7 0.61 10.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KDO30304.1 - 0.0087 16.6 1.6 0.92 10.0 0.9 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KDO30304.1 - 0.0096 15.9 0.1 0.48 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KDO30304.1 - 0.04 14.3 0.9 4 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KDO30304.1 - 0.048 13.8 0.1 8.9 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KDO30304.1 - 0.053 13.4 0.3 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 KDO30304.1 - 0.057 12.6 0.5 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KDO30304.1 - 0.12 12.6 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KDO30304.1 - 0.14 11.9 0.8 7.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Gtr1_RagA PF04670.12 KDO30304.1 - 0.16 11.3 1.5 5.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KDO30304.1 - 0.23 11.1 2.4 15 5.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KDO30304.1 - 0.26 11.2 5.3 5.8 6.8 0.3 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KDO30304.1 - 0.32 10.7 2.8 5.3 6.8 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KDO30304.1 - 0.34 10.5 3.9 1.5 8.4 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KDO30304.1 - 2.3 8.3 5.0 23 5.0 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 KDO30306.1 - 9.9e-67 224.4 66.3 5.8e-36 123.9 26.5 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KDO30306.1 - 1.7e-24 86.8 0.0 9.5e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30306.1 - 2.3e-06 27.7 1.1 0.15 11.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO30306.1 - 5.9e-06 25.9 2.5 0.021 14.6 0.7 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO30306.1 - 0.00018 22.0 0.1 0.082 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KDO30306.1 - 0.00026 20.9 0.9 0.015 15.2 0.3 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KDO30306.1 - 0.00048 20.2 1.4 0.076 13.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_CDR PF06422.12 KDO30306.1 - 0.0019 18.0 5.9 0.077 12.9 0.0 3.5 3 0 0 3 3 2 1 CDR ABC transporter AAA_22 PF13401.6 KDO30306.1 - 0.014 15.7 1.3 5.1 7.4 0.7 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KDO30306.1 - 0.024 13.9 1.4 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KDO30306.1 - 0.037 14.6 0.0 8.5 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KDO30306.1 - 0.042 13.3 0.6 32 3.9 0.1 3.7 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KDO30306.1 - 0.044 13.4 1.3 1.2 8.7 0.5 3.0 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 KDO30306.1 - 0.048 13.2 0.4 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 KDO30306.1 - 0.062 13.7 0.1 12 6.4 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KDO30306.1 - 0.15 12.6 1.3 1.1 9.7 1.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_trans_N PF14510.6 KDO30306.1 - 0.2 12.3 0.0 0.47 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC-transporter N-terminal ABC_ATPase PF09818.9 KDO30306.1 - 0.37 9.5 1.3 1 8.1 0.1 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 KDO30306.1 - 0.52 10.0 1.3 16 5.1 0.5 2.5 2 0 0 2 2 2 0 AAA domain Insulin_TMD PF17870.1 KDO30306.1 - 5.7 7.1 8.6 1.2 9.3 0.0 3.5 3 0 0 3 3 2 0 Insulin receptor trans-membrane segment ABC2_membrane PF01061.24 KDO30307.1 - 3e-66 222.9 66.6 4.1e-35 121.1 28.5 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO30307.1 - 1.8e-30 106.2 0.0 8.5e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30307.1 - 5.2e-06 26.5 0.2 0.037 13.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO30307.1 - 1.2e-05 25.8 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO30307.1 - 1.4e-05 24.7 3.7 0.015 15.1 0.8 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_assoc PF08370.11 KDO30307.1 - 5.5e-05 22.8 1.7 5.5e-05 22.8 1.7 4.5 5 0 0 5 5 3 2 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 KDO30307.1 - 0.00078 19.4 2.3 0.029 14.3 0.4 2.5 2 0 0 2 2 2 1 RsgA GTPase PDR_CDR PF06422.12 KDO30307.1 - 0.0011 18.9 0.6 0.22 11.5 0.1 3.0 2 0 0 2 2 2 1 CDR ABC transporter MMR_HSR1 PF01926.23 KDO30307.1 - 0.0025 17.9 1.7 0.32 11.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO30307.1 - 0.0029 17.9 0.3 1.9 8.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO30307.1 - 0.011 15.1 0.3 35 3.7 0.1 4.3 5 0 0 5 5 5 0 RecF/RecN/SMC N terminal domain DUF5338 PF17273.2 KDO30307.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5338) AAA_25 PF13481.6 KDO30307.1 - 0.015 14.9 0.9 0.3 10.6 0.3 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KDO30307.1 - 0.019 15.5 0.0 8.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO30307.1 - 0.022 15.0 0.7 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KDO30307.1 - 0.073 12.3 2.2 5 6.4 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KDO30307.1 - 0.23 11.5 1.8 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 KDO30307.1 - 0.25 10.8 0.5 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 KDO30307.1 - 0.35 11.3 2.4 0.93 10.0 0.9 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO30307.1 - 0.38 11.0 2.9 19 5.5 0.6 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO30307.1 - 1.1 8.9 2.4 16 5.1 0.5 2.4 2 0 0 2 2 2 0 AAA domain DNA_alkylation PF08713.11 KDO30308.1 - 1.5e-33 116.3 0.1 2.3e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF21 PF01595.20 KDO30309.1 - 3.6e-30 105.0 5.9 6.2e-30 104.2 5.9 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO30309.1 - 8.7e-06 26.1 0.0 3.2e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 CBS domain ABC2_membrane PF01061.24 KDO30310.1 - 2.8e-56 190.2 49.5 1.4e-36 125.9 30.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO30310.1 - 3.4e-28 98.9 0.0 4.8e-16 59.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30310.1 - 2.1e-06 27.8 0.2 1.1 9.0 0.0 3.4 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO30310.1 - 2.6e-06 27.1 4.6 0.016 15.0 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO30310.1 - 2.9e-06 27.3 2.3 0.012 15.6 0.4 2.3 2 0 0 2 2 2 2 RsgA GTPase PDR_assoc PF08370.11 KDO30310.1 - 3.3e-06 26.8 3.8 9.9e-06 25.2 0.7 4.0 5 0 0 5 5 3 2 Plant PDR ABC transporter associated AAA_16 PF13191.6 KDO30310.1 - 3.6e-06 27.5 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain PDR_CDR PF06422.12 KDO30310.1 - 3.8e-05 23.5 0.2 3.8e-05 23.5 0.2 3.6 5 0 0 5 5 2 1 CDR ABC transporter AAA_22 PF13401.6 KDO30310.1 - 0.00017 21.9 0.1 0.79 10.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KDO30310.1 - 0.00055 19.9 0.1 0.043 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KDO30310.1 - 0.00062 19.1 0.1 0.21 10.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KDO30310.1 - 0.001 19.6 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KDO30310.1 - 0.0019 17.4 40.6 0.16 11.1 6.3 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA PF00004.29 KDO30310.1 - 0.002 18.6 0.7 4.9 7.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO30310.1 - 0.0023 17.5 1.1 0.68 9.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KDO30310.1 - 0.0035 17.4 0.3 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KDO30310.1 - 0.0058 16.6 1.2 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KDO30310.1 - 0.0086 15.8 0.9 2.1 8.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KDO30310.1 - 0.0094 15.4 1.1 13 5.1 0.0 3.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO30310.1 - 0.012 16.1 2.3 0.52 10.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO30310.1 - 0.012 15.8 0.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 KDO30310.1 - 0.037 14.0 0.2 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KDO30310.1 - 0.038 14.4 0.4 7.2 7.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Gtr1_RagA PF04670.12 KDO30310.1 - 0.057 12.8 1.3 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region cobW PF02492.19 KDO30310.1 - 0.06 12.9 2.2 0.71 9.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KDO30310.1 - 0.081 13.1 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KDO30310.1 - 0.095 12.4 1.8 4 7.2 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KDO30310.1 - 0.11 12.4 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 KDO30310.1 - 0.12 11.6 0.3 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KDO30310.1 - 0.15 11.6 2.0 0.72 9.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KDO30310.1 - 0.22 11.8 1.3 15 5.8 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO30310.1 - 0.23 11.1 2.7 13 5.4 0.5 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KDO30310.1 - 0.28 11.2 1.0 5.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KDO30310.1 - 2 8.5 4.9 24 4.9 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain GATA PF00320.27 KDO30311.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 GATA zinc finger Porphobil_deam PF01379.20 KDO30312.1 - 7.6e-69 231.3 0.0 1.1e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KDO30312.1 - 1.7e-17 63.5 0.3 3.5e-17 62.5 0.3 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain VASt PF16016.5 KDO30315.1 - 2.3e-26 93.0 0.0 4.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KDO30315.1 - 3.6e-11 42.9 0.2 7.4e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 GRAM domain YMF19 PF02326.15 KDO30315.1 - 0.084 13.7 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Plant ATP synthase F0 Phageshock_PspG PF09583.10 KDO30315.1 - 1.4 9.3 4.4 0.35 11.2 1.0 1.7 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) DJ-1_PfpI PF01965.24 KDO30316.1 - 1.9e-49 167.6 0.0 2.2e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KDO30316.1 - 0.001 18.8 0.0 0.0098 15.6 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase PF00117.28 KDO30316.1 - 0.0022 17.8 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KDO30316.1 - 0.0039 17.0 0.1 0.13 12.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 KDO30316.1 - 0.041 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 KDO30316.1 - 0.093 11.8 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain TMEM234 PF10639.9 KDO30317.1 - 3.8e-31 107.5 0.1 6.1e-31 106.9 0.1 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 zf-C3HC4_3 PF13920.6 KDO30318.1 - 1.5e-11 44.0 5.2 2.5e-11 43.2 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 KDO30318.1 - 2.4e-06 27.6 0.3 2.4e-06 27.6 0.3 2.2 1 1 1 2 2 2 1 K-box region zf-C3HC4 PF00097.25 KDO30318.1 - 0.00028 20.7 2.9 0.00066 19.5 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO30318.1 - 0.0029 17.4 4.3 0.0051 16.7 4.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO30318.1 - 0.073 13.4 4.8 0.16 12.3 4.8 1.6 1 0 0 1 1 1 0 Ring finger domain KxDL PF10241.9 KDO30318.1 - 0.16 12.2 7.1 6.7 7.1 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein UPF0242 PF06785.11 KDO30318.1 - 0.19 11.8 6.3 0.31 11.1 4.4 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus zf-RING_5 PF14634.6 KDO30318.1 - 0.54 10.3 3.2 1.1 9.3 3.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Fer2 PF00111.27 KDO30318.1 - 0.57 10.2 3.9 0.72 9.8 2.5 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain SOBP PF15279.6 KDO30319.1 - 1.3 9.5 25.1 1.9 9.0 25.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SLC12 PF03522.15 KDO30319.1 - 6.1 5.7 15.5 7.2 5.5 15.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SRP-alpha_N PF04086.13 KDO30319.1 - 6.6 6.6 33.1 8.7 6.2 33.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3357 PF11837.8 KDO30320.1 - 0.0066 16.9 1.6 2.1 8.9 1.3 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF3357) stn_TNFRSF12A PF12191.8 KDO30320.1 - 0.42 10.8 4.2 0.45 10.7 0.1 2.6 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TFIIA PF03153.13 KDO30320.1 - 2.7 7.9 7.7 3.5 7.5 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KDO30320.1 - 9.8 4.7 8.9 11 4.5 8.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 KDO30321.1 - 1.2e-66 224.8 0.0 1.5e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30321.1 - 6.6e-36 123.9 0.1 8.6e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 KDO30321.1 - 1.8e-34 118.0 0.1 1.8e-34 118.0 0.1 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 KDO30321.1 - 3e-08 33.3 0.0 2e-07 30.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO30321.1 - 1.8e-06 27.0 0.0 3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO30321.1 - 0.0031 17.5 0.0 0.048 13.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KDO30321.1 - 0.023 14.3 0.7 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KDO30321.1 - 0.03 13.4 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KDO30321.1 - 0.035 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CUE PF02845.16 KDO30323.1 - 1.8e-05 24.3 0.1 4.8e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 CUE domain Glyco_transf_41 PF13844.6 KDO30324.1 - 9.3e-77 258.4 1.0 5e-38 130.7 0.2 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KDO30324.1 - 3.9e-17 61.3 15.5 0.00028 20.6 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30324.1 - 2.4e-12 46.0 26.9 0.18 12.0 0.0 10.3 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 KDO30324.1 - 1.2e-10 41.5 43.8 4.6e-05 23.6 0.7 8.4 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO30324.1 - 1.6e-09 37.4 22.2 0.2 12.1 0.1 9.2 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30324.1 - 2e-09 37.5 23.7 0.63 11.0 0.0 9.1 7 1 1 8 8 8 4 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.6 KDO30324.1 - 8.5e-09 36.0 0.0 3.1e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_8 PF13181.6 KDO30324.1 - 1.2e-08 34.5 14.2 0.053 13.8 0.0 7.7 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30324.1 - 2.1e-07 30.5 18.7 0.05 13.7 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO30324.1 - 2.8e-06 27.0 32.3 0.014 15.3 0.1 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 KDO30324.1 - 3.3e-06 26.8 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_16 PF13432.6 KDO30324.1 - 1.4e-05 25.7 39.7 0.00021 21.9 0.2 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30324.1 - 2.4e-05 23.9 21.3 0.0054 16.4 0.1 6.9 8 0 0 8 8 8 2 TPR repeat Glyco_transf_4 PF13439.6 KDO30324.1 - 0.002 18.2 0.4 0.0069 16.4 0.4 2.0 1 0 0 1 1 1 1 Glycosyltransferase Family 4 TPR_9 PF13371.6 KDO30324.1 - 0.0025 17.9 15.7 0.039 14.1 0.3 5.8 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO30324.1 - 0.011 16.2 1.2 0.011 16.2 1.2 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat SRA1 PF07304.11 KDO30324.1 - 0.16 11.8 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) PHD PF00628.29 KDO30325.1 - 5e-29 99.9 56.6 4.7e-10 39.2 9.0 4.6 4 0 0 4 4 4 4 PHD-finger DDT PF02791.17 KDO30325.1 - 1.6e-13 50.7 1.4 2.9e-13 49.9 1.4 1.5 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KDO30325.1 - 1.8e-11 44.4 0.4 1.8e-11 44.4 0.4 5.1 4 2 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 KDO30325.1 - 1.9e-07 30.5 37.0 0.0029 17.1 0.2 5.7 5 0 0 5 5 5 4 PHD-finger WHIM1 PF15612.6 KDO30325.1 - 0.0019 17.7 0.0 0.0053 16.3 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 zf-BED PF02892.15 KDO30325.1 - 0.6 10.2 7.8 19 5.4 0.0 4.6 4 0 0 4 4 4 0 BED zinc finger FAM178 PF14816.6 KDO30326.1 - 0.00047 19.2 0.0 0.0011 18.0 0.0 1.6 1 1 0 1 1 1 1 Family of unknown function, FAM178 CDC27 PF09507.10 KDO30326.1 - 1.4 8.2 11.7 2.1 7.6 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rop PF01815.16 KDO30326.1 - 1.7 8.6 5.4 1.4 8.9 0.9 2.4 2 0 0 2 2 2 0 Rop protein EamA PF00892.20 KDO30327.1 - 3.6e-15 56.3 39.0 1.2e-07 31.9 14.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family Tmemb_18A PF09771.9 KDO30327.1 - 5.9 7.3 7.5 5.8 7.4 0.2 3.3 4 0 0 4 4 4 0 Transmembrane protein 188 HTH_Tnp_Tc5 PF03221.16 KDO30329.1 - 3.9e-11 42.8 0.6 1.2e-10 41.3 0.4 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Cytotoxic PF09000.10 KDO30329.1 - 0.037 14.4 0.5 0.21 12.0 0.1 2.2 1 1 0 2 2 2 0 Cytotoxic Arf PF00025.21 KDO30330.1 - 1.6e-72 242.6 0.5 1.8e-72 242.4 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO30330.1 - 2.9e-14 53.3 0.1 4.1e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO30330.1 - 3.4e-12 46.2 0.0 4.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KDO30330.1 - 5.7e-11 42.2 2.6 1.3e-05 24.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KDO30330.1 - 2.5e-09 36.8 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KDO30330.1 - 2.7e-09 36.7 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KDO30330.1 - 2.8e-07 30.6 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO30330.1 - 4.8e-05 23.0 0.0 0.00076 19.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KDO30330.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KDO30330.1 - 0.058 13.3 0.2 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PPK2 PF03976.14 KDO30330.1 - 0.84 9.1 2.8 1.3 8.4 0.2 2.2 2 1 1 3 3 3 0 Polyphosphate kinase 2 (PPK2) Clat_adaptor_s PF01217.20 KDO30331.1 - 1.3e-51 174.3 2.3 1.5e-51 174.1 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CR6_interact PF10147.9 KDO30332.1 - 0.036 13.8 5.8 0.047 13.4 5.8 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DivIC PF04977.15 KDO30332.1 - 5.5 6.8 13.0 0.69 9.7 1.0 2.1 1 1 1 2 2 2 0 Septum formation initiator RNA_pol_3_Rpc31 PF11705.8 KDO30333.1 - 0.039 14.2 1.1 0.058 13.6 1.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 KDO30333.1 - 0.082 13.3 11.6 0.24 11.8 11.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KDO30333.1 - 0.11 12.2 1.5 0.24 11.1 1.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KDO30333.1 - 6.9 5.9 9.6 11 5.2 9.6 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_12 PF13087.6 KDO30334.1 - 0.076 12.6 0.6 0.096 12.3 0.6 1.2 1 0 0 1 1 1 0 AAA domain Vps16_N PF04841.13 KDO30335.1 - 1.9e-61 208.1 0.0 2.9e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KDO30335.1 - 1.8e-52 178.4 3.3 4.8e-52 177.0 2.6 1.9 2 0 0 2 2 2 1 Vps16, C-terminal region DUF4375 PF14300.6 KDO30335.1 - 0.0025 18.1 0.2 4.4 7.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4375) ANAPC4_WD40 PF12894.7 KDO30335.1 - 0.03 14.6 0.0 0.5 10.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.11 KDO30335.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain CotH PF08757.11 KDO30336.1 - 0.042 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 CotH kinase protein Sec63 PF02889.16 KDO30337.1 - 4.6e-100 334.0 0.0 1.3e-70 237.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KDO30337.1 - 5.9e-56 189.0 1.9 2.4e-29 102.3 0.7 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KDO30337.1 - 5.5e-27 94.9 0.0 7.3e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO30337.1 - 1.1e-16 61.2 0.0 7.7e-08 32.7 0.0 3.5 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KDO30337.1 - 6.1e-09 36.3 0.5 0.0022 18.3 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KDO30337.1 - 1.4e-06 28.7 6.9 0.004 17.5 0.5 3.4 4 0 0 4 4 4 2 AAA domain Helicase_PWI PF18149.1 KDO30337.1 - 0.00017 21.7 0.1 0.00098 19.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain T2SSE PF00437.20 KDO30337.1 - 0.00022 20.4 0.0 1.3 8.1 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein UvrD-helicase PF00580.21 KDO30337.1 - 0.00034 20.2 0.9 0.12 11.9 0.1 2.9 4 0 0 4 4 4 2 UvrD/REP helicase N-terminal domain SWI2_SNF2 PF18766.1 KDO30337.1 - 0.0012 18.5 0.3 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase PhoH PF02562.16 KDO30337.1 - 0.0019 17.7 0.1 1.1 8.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 KDO30337.1 - 0.0061 16.1 0.1 2.2 7.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 KDO30337.1 - 0.23 10.8 3.7 11 5.4 0.3 3.4 2 1 0 3 3 3 0 Bacterial TniB protein AAA_11 PF13086.6 KDO30337.1 - 0.59 9.9 6.4 0.84 9.4 0.1 3.7 3 2 2 5 5 5 0 AAA domain TPR_1 PF00515.28 KDO30338.1 - 2.2e-12 46.2 13.0 8.3e-07 28.6 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30338.1 - 2.3e-11 42.9 14.2 6.4e-07 29.0 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TTC5_OB PF16669.5 KDO30338.1 - 5.3e-11 42.2 0.0 9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_8 PF13181.6 KDO30338.1 - 1e-09 37.8 3.5 0.004 17.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30338.1 - 1.1e-09 37.8 6.0 0.004 16.8 0.2 4.6 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 KDO30338.1 - 2.5e-07 31.2 12.1 0.0055 17.3 3.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO30338.1 - 1.3e-05 25.4 2.1 0.06 13.6 0.3 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO30338.1 - 2.4e-05 24.4 4.3 0.87 10.1 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30338.1 - 8.7e-05 23.0 5.2 0.62 11.0 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30338.1 - 0.00042 20.1 0.4 0.2 11.8 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO30338.1 - 0.00042 20.8 9.7 0.0098 16.4 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Ax_dynein_light PF10211.9 KDO30339.1 - 1e-75 253.8 3.6 1.2e-75 253.6 3.6 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain DUF572 PF04502.13 KDO30339.1 - 0.017 14.7 2.7 0.026 14.2 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GrpE PF01025.19 KDO30339.1 - 0.33 10.6 4.9 0.24 11.1 3.2 1.6 2 0 0 2 2 2 0 GrpE zf-RING_2 PF13639.6 KDO30340.1 - 6.2e-10 39.2 11.8 1e-09 38.6 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO30340.1 - 9.8e-07 28.4 8.1 1.8e-06 27.5 8.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO30340.1 - 3e-06 27.0 11.9 5.2e-06 26.2 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30340.1 - 1.2e-05 25.5 10.1 2.3e-05 24.6 10.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO30340.1 - 4.6e-05 23.3 11.1 7.4e-05 22.6 11.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO30340.1 - 0.00022 21.0 12.0 0.00037 20.3 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO30340.1 - 0.00027 20.5 10.2 0.00043 19.8 10.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KDO30340.1 - 0.001 18.9 8.2 0.0017 18.2 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 KDO30340.1 - 0.026 14.7 4.4 0.056 13.7 4.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf-ANAPC11 PF12861.7 KDO30340.1 - 0.048 13.7 7.2 0.12 12.4 7.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-ribbon_3 PF13248.6 KDO30340.1 - 0.055 12.9 0.7 0.42 10.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_UBOX PF13445.6 KDO30340.1 - 0.18 11.8 9.7 0.36 10.9 9.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KDO30340.1 - 0.36 10.9 11.5 0.73 9.9 11.5 1.5 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KDO30340.1 - 3 8.0 8.6 7.5 6.8 8.6 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 KDO30340.1 - 6.2 6.8 11.7 12 5.8 11.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KDO30340.1 - 7.2 7.0 11.1 14 6.0 11.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_2 PF13639.6 KDO30341.1 - 1.1e-07 32.1 4.1 1.8e-07 31.4 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO30341.1 - 3.2e-06 26.9 4.4 5.4e-06 26.1 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30341.1 - 5e-06 26.7 4.6 9.6e-06 25.8 4.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO30341.1 - 5e-05 23.2 2.0 8.6e-05 22.4 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO30341.1 - 0.00011 22.0 3.2 0.00019 21.2 3.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO30341.1 - 0.00013 21.6 0.5 0.0003 20.4 0.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KDO30341.1 - 0.00013 21.5 2.7 0.00024 20.7 2.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KDO30341.1 - 0.00015 21.5 2.5 0.00026 20.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO30341.1 - 0.021 14.9 1.5 0.043 13.9 1.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KDO30341.1 - 0.037 14.1 3.5 0.08 13.0 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger zinc_ribbon_16 PF17034.5 KDO30341.1 - 0.05 13.8 1.0 0.092 13.0 1.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 KDO30341.1 - 0.067 13.1 5.2 0.12 12.3 5.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO30341.1 - 0.089 12.8 1.1 0.18 11.8 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KDO30341.1 - 0.68 10.3 4.8 1.2 9.5 4.8 1.4 1 0 0 1 1 1 0 RING-like domain TFIIA PF03153.13 KDO30341.1 - 2.9 7.8 9.3 0.74 9.7 5.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ZZ PF00569.17 KDO30342.1 - 2.9e-29 100.6 8.5 4e-11 42.5 0.1 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 KDO30342.1 - 7.7e-27 94.0 0.0 2e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 KDO30342.1 - 1.2e-08 34.7 0.0 1.9e-07 30.9 0.0 2.6 2 0 0 2 2 2 1 PB1 domain CUE PF02845.16 KDO30342.1 - 0.12 12.1 0.9 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 CUE domain DZR PF12773.7 KDO30342.1 - 2.1 8.5 11.2 3.9e+03 -2.0 11.2 3.6 1 1 0 1 1 1 0 Double zinc ribbon PRKCSH_1 PF13015.6 KDO30343.1 - 5.6e-30 104.1 0.0 9e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 KDO30343.1 - 2.8e-25 89.1 1.0 6.2e-25 88.0 1.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH PF07915.13 KDO30343.1 - 0.062 14.3 0.6 0.24 12.4 0.6 2.0 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 KDO30343.1 - 2 8.7 12.8 0.17 12.1 1.8 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A RCC1_2 PF13540.6 KDO30344.1 - 4.6e-62 204.8 82.1 4.3e-08 32.7 1.3 14.5 14 0 0 14 14 14 12 Regulator of chromosome condensation (RCC1) repeat FXa_inhibition PF14670.6 KDO30344.1 - 3.9e-14 52.6 92.4 6.5e-07 29.5 6.5 8.3 7 0 0 7 7 7 5 Coagulation Factor Xa inhibitory site FGE-sulfatase PF03781.16 KDO30344.1 - 4.8e-08 32.9 0.9 0.073 12.6 0.0 4.8 6 0 0 6 6 6 3 Sulfatase-modifying factor enzyme 1 cEGF PF12662.7 KDO30344.1 - 1.2e-05 25.1 12.5 0.0001 22.2 2.9 7.2 7 1 0 7 7 7 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KDO30344.1 - 1.3e-05 25.3 6.0 1.3e-05 25.3 6.0 7.8 7 0 0 7 7 7 4 Calcium-binding EGF domain Intimin_C PF07979.11 KDO30344.1 - 0.0048 17.3 9.7 20 5.7 0.1 6.7 6 1 0 6 6 6 1 Intimin C-type lectin domain Aminotran_1_2 PF00155.21 KDO30345.1 - 1.4e-42 146.2 0.0 1.7e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KDO30345.1 - 0.073 11.6 0.0 0.17 10.4 0.0 1.6 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 KDO30346.1 - 2.5e-71 240.1 0.0 3.1e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30346.1 - 1.6e-33 116.1 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO30346.1 - 0.016 14.6 0.2 0.046 13.1 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO30346.1 - 0.024 13.9 0.0 0.12 11.7 0.0 1.9 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 KDO30346.1 - 0.04 13.5 0.3 0.79 9.3 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO30346.1 - 0.054 12.4 0.2 0.1 11.5 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Spa1_C PF18218.1 KDO30346.1 - 0.096 13.1 0.1 12 6.4 0.0 2.9 2 1 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain FSIP2 PF15783.5 KDO30346.1 - 0.11 10.4 0.0 0.16 9.9 0.0 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Diphthamide_syn PF01866.17 KDO30347.1 - 2.1e-115 385.3 0.0 2.7e-115 385.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF5331 PF17265.2 KDO30347.1 - 0.18 11.6 0.0 0.57 9.9 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5331) PHM7_cyt PF14703.6 KDO30348.1 - 3.3e-09 37.2 0.0 5.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KDO30348.1 - 2.5e-08 33.8 7.2 2.5e-08 33.8 7.2 2.2 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport MinC_C PF03775.16 KDO30349.1 - 3.7e-28 97.5 0.2 3.7e-28 97.5 0.2 1.9 2 0 0 2 2 2 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 KDO30349.1 - 0.00074 18.2 0.8 0.0011 17.7 0.8 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Sod_Fe_C PF02777.18 KDO30350.1 - 2e-41 140.3 0.7 4.1e-41 139.3 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KDO30350.1 - 2e-29 101.8 1.2 3.6e-29 101.0 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pyr_redox_2 PF07992.14 KDO30351.1 - 3.5e-15 56.0 0.0 4.2e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO30351.1 - 4.2e-05 23.7 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KDO30351.1 - 0.00037 19.8 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KDO30351.1 - 0.0055 16.0 0.0 0.33 10.2 0.0 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KDO30351.1 - 0.0072 16.8 0.3 1.9 9.0 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KDO30351.1 - 0.016 15.2 0.0 0.054 13.5 0.0 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KDO30351.1 - 0.041 14.4 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KDO30351.1 - 0.052 13.6 0.0 24 5.0 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KDO30351.1 - 0.052 13.1 0.1 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 KDO30351.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KDO30351.1 - 0.19 10.9 0.0 3.5 6.8 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L2_C PF03947.18 KDO30353.1 - 8.5e-48 161.7 2.8 1.1e-47 161.4 2.2 1.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KDO30353.1 - 1.3e-16 60.3 0.2 4.1e-16 58.7 0.2 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Myosin_N PF02736.19 KDO30353.1 - 0.16 11.9 0.7 2.6 7.9 0.2 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Pkinase PF00069.25 KDO30354.1 - 2.5e-44 151.6 0.0 3e-30 105.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30354.1 - 1.9e-16 60.1 0.0 2.6e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO30354.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF4231 PF14015.6 KDO30355.1 - 0.0084 16.6 1.4 0.0084 16.6 1.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) DUF5134 PF17197.4 KDO30355.1 - 1.7 8.5 9.0 6.7 6.6 9.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) AAA_16 PF13191.6 KDO30356.1 - 7e-05 23.3 0.1 0.0015 18.9 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO30356.1 - 0.00028 20.7 0.0 0.00074 19.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KDO30356.1 - 0.00079 19.7 0.0 0.054 13.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KDO30356.1 - 0.0033 17.4 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KDO30356.1 - 0.0068 16.2 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 KDO30356.1 - 0.0073 16.8 0.0 0.025 15.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 KDO30356.1 - 0.017 15.4 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KDO30356.1 - 0.025 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO30356.1 - 0.046 14.3 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO30356.1 - 0.064 13.6 0.5 0.28 11.5 0.0 2.1 2 1 1 3 3 3 0 AAA domain HrpB7 PF09486.10 KDO30356.1 - 0.065 13.6 2.7 0.12 12.7 2.7 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) AAA_7 PF12775.7 KDO30356.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO30356.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase zf-CCCH PF00642.24 KDO30356.1 - 0.11 12.5 0.5 0.46 10.5 0.5 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rad17 PF03215.15 KDO30356.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KDO30356.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO30356.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO30356.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HCNGP PF07818.13 KDO30357.1 - 5.9e-20 71.7 0.0 8.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein RCC1 PF00415.18 KDO30358.1 - 8e-60 199.3 35.7 2.7e-11 43.9 0.5 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO30358.1 - 2.3e-15 55.9 58.3 0.00011 21.9 2.0 8.4 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 KDO30358.1 - 0.00021 21.0 0.6 0.00047 19.8 0.1 2.0 2 0 0 2 2 2 1 SAP domain GGDEF_2 PF17853.1 KDO30358.1 - 0.012 15.9 0.5 0.038 14.2 0.2 1.9 2 0 0 2 2 2 0 GGDEF-like domain Keratin PF02422.16 KDO30358.1 - 2.1 8.1 5.4 1.4 8.7 1.3 2.5 1 1 1 2 2 2 0 Keratin Guanylate_cyc PF00211.20 KDO30359.1 - 8.4e-97 322.1 0.2 8.1e-49 165.7 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1266 PF06889.11 KDO30359.1 - 9.4 6.2 9.6 6.3 6.8 7.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DAO PF01266.24 KDO30361.1 - 1.7e-46 159.5 0.2 1.9e-46 159.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO30361.1 - 3.9e-05 22.5 0.8 0.024 13.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KDO30361.1 - 0.0057 15.8 0.4 0.31 10.1 0.1 2.7 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KDO30361.1 - 0.022 13.9 0.4 0.4 9.7 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KDO30361.1 - 0.062 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KDO30361.1 - 0.11 12.8 0.0 0.38 11.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO30361.1 - 0.13 11.5 0.5 1.2 8.4 0.5 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KDO30361.1 - 0.13 11.9 0.2 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA EF-hand_7 PF13499.6 KDO30362.1 - 4.7e-05 23.8 0.0 0.063 13.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO30362.1 - 0.0065 16.8 0.0 4.1 7.8 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_6 PF13405.6 KDO30362.1 - 0.011 15.6 0.0 0.12 12.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 KDO30362.1 - 0.05 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KDO30362.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 EF hand DUF3995 PF13160.6 KDO30363.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Podoplanin PF05808.11 KDO30364.1 - 0.0012 18.9 12.8 0.0064 16.6 12.4 2.3 1 1 0 1 1 1 1 Podoplanin Shisa PF13908.6 KDO30364.1 - 0.036 14.3 0.4 0.036 14.3 0.4 2.6 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator Mid2 PF04478.12 KDO30364.1 - 0.098 12.5 0.1 0.34 10.7 0.1 1.9 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MGC-24 PF05283.11 KDO30364.1 - 0.17 12.3 0.2 0.17 12.3 0.2 3.4 2 2 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GDC-P PF02347.16 KDO30366.1 - 7.1e-192 638.0 0.1 2e-174 580.5 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KDO30366.1 - 1.4e-08 34.1 0.1 4.8e-07 29.1 0.1 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KDO30366.1 - 0.00029 20.2 0.1 0.00056 19.3 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KDO30366.1 - 0.0024 16.4 0.0 0.0077 14.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme TraI PF07057.11 KDO30366.1 - 0.0095 16.1 0.0 0.045 13.9 0.0 2.2 1 0 0 1 1 1 1 DNA helicase TraI TPR_1 PF00515.28 KDO30367.1 - 5.8e-08 32.2 6.3 0.00018 21.2 1.7 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30367.1 - 2.3e-07 30.4 7.4 0.0012 18.7 1.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30367.1 - 0.00049 20.7 14.0 0.0017 19.0 2.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30367.1 - 0.00051 19.7 0.9 0.0013 18.3 0.9 1.8 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.6 KDO30367.1 - 0.0036 17.4 1.6 0.0036 17.4 1.6 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO30367.1 - 0.029 15.0 13.8 0.049 14.3 2.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30367.1 - 0.041 14.1 0.5 0.97 9.8 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Peroxidase_ext PF11895.8 KDO30367.1 - 0.058 13.3 0.7 0.74 9.8 0.0 2.3 2 0 0 2 2 2 0 Fungal peroxidase extension region TPR_19 PF14559.6 KDO30367.1 - 0.069 13.7 5.8 4.3 7.9 0.9 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO30367.1 - 0.15 12.8 4.2 0.55 11.0 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat AATF-Che1 PF13339.6 KDO30367.1 - 0.46 11.2 5.5 0.4 11.3 3.1 2.1 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Apelin PF15360.6 KDO30367.1 - 0.66 10.6 3.8 3.4 8.3 0.0 2.6 2 1 0 2 2 2 0 APJ endogenous ligand Trp_syntA PF00290.20 KDO30368.1 - 4.4e-84 281.4 0.1 5.1e-84 281.2 0.1 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 KDO30368.1 - 0.0044 16.5 0.0 0.054 13.0 0.0 2.3 1 1 1 3 3 3 1 Histidine biosynthesis protein PA PF02225.22 KDO30368.1 - 0.038 14.0 0.7 0.12 12.4 0.1 2.4 2 1 0 2 2 2 0 PA domain Astacin PF01400.24 KDO30369.1 - 4.3e-15 55.8 0.0 7.5e-14 51.8 0.0 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Rieske PF00355.26 KDO30369.1 - 0.13 12.2 8.9 0.89 9.5 0.5 3.5 3 1 1 4 4 4 0 Rieske [2Fe-2S] domain Metallopep PF12044.8 KDO30369.1 - 0.38 9.3 2.2 0.56 8.8 2.2 1.1 1 0 0 1 1 1 0 Putative peptidase family Tfb4 PF03850.14 KDO30370.1 - 3.2e-81 272.8 0.0 4.4e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 GyrI-like PF06445.15 KDO30371.1 - 1.2e-13 51.7 0.1 3.8e-13 50.0 0.1 1.7 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 KDO30371.1 - 1.4e-06 28.6 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Integron-associated effector binding protein Herpes_ori_bp PF02399.15 KDO30373.1 - 0.066 11.3 0.1 0.087 10.9 0.1 1.1 1 0 0 1 1 1 0 Origin of replication binding protein GFO_IDH_MocA PF01408.22 KDO30374.1 - 1e-18 68.3 0.1 3.3e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KDO30374.1 - 4e-10 39.7 0.0 1.3e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain PH PF00169.29 KDO30375.1 - 4.6e-13 49.6 0.2 1.9e-12 47.6 0.1 2.1 2 0 0 2 2 2 1 PH domain C2 PF00168.30 KDO30375.1 - 1.4e-11 44.6 0.1 4e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 C2 domain PDZ PF00595.24 KDO30375.1 - 1.6e-07 31.6 0.2 0.022 15.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PH_11 PF15413.6 KDO30375.1 - 1.1e-06 29.0 1.1 5.8e-06 26.7 0.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PDZ_6 PF17820.1 KDO30375.1 - 2.4e-06 27.3 0.0 0.0074 16.1 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO30375.1 - 0.00072 19.8 0.2 1.6 9.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PH_8 PF15409.6 KDO30375.1 - 0.07 13.4 1.0 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain zf-RanBP PF00641.18 KDO30375.1 - 0.16 11.3 1.9 0.31 10.4 1.9 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others WH2 PF02205.20 KDO30375.1 - 1.5 8.7 7.9 4 7.4 0.7 3.7 4 0 0 4 4 4 0 WH2 motif C2 PF00168.30 KDO30376.1 - 2.1e-15 56.8 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KDO30376.1 - 3.5e-15 56.4 0.0 6.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PDZ_6 PF17820.1 KDO30376.1 - 2e-11 43.5 0.0 9.2e-06 25.4 0.0 3.1 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KDO30376.1 - 4.1e-10 39.9 0.2 0.0014 18.9 0.1 3.1 2 0 0 2 2 2 2 PDZ domain PH_11 PF15413.6 KDO30376.1 - 2.3e-07 31.2 0.1 6.7e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ_2 PF13180.6 KDO30376.1 - 0.012 15.9 0.4 0.095 13.0 0.0 2.6 3 0 0 3 3 3 0 PDZ domain HoxA13_N PF12284.8 KDO30377.1 - 0.0044 17.6 0.7 0.008 16.8 0.7 1.3 1 0 0 1 1 1 1 Hox protein A13 N terminal Peptidase_C1 PF00112.23 KDO30378.1 - 2.4e-20 73.6 1.6 2.6e-20 73.5 1.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO30378.1 - 0.0034 16.2 0.0 0.004 16.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO30379.1 - 1.7e-59 201.6 9.6 2.1e-59 201.2 9.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO30379.1 - 6.5e-05 21.9 0.4 0.056 12.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Kinesin PF00225.23 KDO30380.1 - 7.3e-118 393.3 0.1 7.3e-118 393.3 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30380.1 - 1.4e-27 96.4 0.4 4.5e-27 94.8 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding CHDCT2 PF08074.11 KDO30380.1 - 2.9 8.0 16.1 0.75 9.9 11.3 2.4 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain CoaE PF01121.20 KDO30381.1 - 1.7e-53 180.9 0.1 2.3e-53 180.5 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KDO30381.1 - 2.4e-05 24.9 0.2 0.00028 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO30381.1 - 0.00035 20.7 0.0 0.0014 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KDO30381.1 - 0.0022 18.2 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.17 KDO30382.1 - 0.16 12.1 8.5 1.9 8.8 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Anoctamin PF04547.12 KDO30383.1 - 2.9e-106 356.0 17.2 3.7e-106 355.7 17.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO30383.1 - 0.0079 15.9 0.3 0.24 11.1 0.1 2.1 1 1 1 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin PHD PF00628.29 KDO30384.1 - 8.9e-05 22.3 8.9 8.9e-05 22.3 8.9 2.0 2 0 0 2 2 2 1 PHD-finger CDC45 PF02724.14 KDO30384.1 - 0.17 10.1 5.5 0.25 9.6 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 KDO30384.1 - 4.7 5.9 8.8 7 5.3 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) P3A PF08727.11 KDO30384.1 - 4.8 6.6 6.6 2.2 7.7 0.2 2.6 2 0 0 2 2 2 0 Poliovirus 3A protein like PRP38_assoc PF12871.7 KDO30384.1 - 9.7 6.9 23.1 0.081 13.5 14.3 2.1 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Solute_trans_a PF03619.16 KDO30385.1 - 3.3e-80 269.4 14.1 3.1e-59 200.7 5.0 2.0 1 1 1 2 2 2 2 Organic solute transporter Ostalpha Cnd2 PF05786.14 KDO30386.1 - 2.1e-103 347.5 37.7 1e-102 345.2 35.4 2.3 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KDO30386.1 - 0.00041 20.5 0.1 0.0019 18.4 0.1 2.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Peptidase_S10 PF00450.22 KDO30387.1 - 2.9e-98 330.0 0.0 3.3e-98 329.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Skp1 PF01466.19 KDO30388.1 - 2.4e-18 66.0 0.0 3.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KDO30388.1 - 5.4e-18 64.9 0.1 1.1e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KDO30388.1 - 0.0017 18.6 0.1 0.015 15.5 0.1 2.0 1 1 0 1 1 1 1 BTB/POZ domain Pro-kuma_activ PF09286.11 KDO30389.1 - 6.6e-15 55.7 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KDO30389.1 - 0.00049 19.5 0.2 0.00076 18.8 0.2 1.2 1 0 0 1 1 1 1 Subtilase family PPP1R35_C PF15503.6 KDO30389.1 - 0.2 11.5 0.0 0.49 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus ThrE PF06738.12 KDO30390.1 - 5.4 6.3 5.3 2.6 7.3 1.3 2.5 2 0 0 2 2 2 0 Putative threonine/serine exporter Pkinase PF00069.25 KDO30391.1 - 9.1e-67 225.2 0.0 1.3e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30391.1 - 8.5e-37 126.8 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 KDO30391.1 - 2.7e-12 46.6 11.6 4.4e-12 45.9 11.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger Arb2 PF09757.9 KDO30391.1 - 8.3e-05 21.8 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain Pkinase_C PF00433.24 KDO30391.1 - 0.00029 21.5 0.3 0.0014 19.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KDO30391.1 - 0.00099 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FYVE_2 PF02318.16 KDO30391.1 - 0.0045 17.2 5.1 0.0087 16.3 5.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Kinase-like PF14531.6 KDO30391.1 - 0.037 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TubC_N PF18563.1 KDO30392.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TubC N-terminal docking domain XPG_I PF00867.18 KDO30393.1 - 5.8e-27 93.9 0.3 1.7e-26 92.4 0.3 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KDO30393.1 - 2.5e-20 72.8 0.0 5.6e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KDO30393.1 - 1e-08 34.9 0.3 3e-08 33.5 0.1 1.9 3 0 0 3 3 3 1 XPG domain containing TPR_1 PF00515.28 KDO30393.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat 5_3_exonuc PF01367.20 KDO30393.1 - 0.018 15.6 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 KDO30393.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30393.1 - 0.095 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TMEM138 PF14935.6 KDO30394.1 - 3.4e-19 69.7 0.7 5e-19 69.1 0.7 1.2 1 0 0 1 1 1 1 Transmembrane protein 138 AAA PF00004.29 KDO30395.1 - 4.5e-36 124.2 0.0 7.9e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO30395.1 - 3.2e-07 30.0 0.0 1.2e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KDO30395.1 - 7.9e-07 29.0 0.0 2.5e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KDO30395.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KDO30395.1 - 4e-05 23.4 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO30395.1 - 0.00041 20.4 0.0 0.0024 17.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO30395.1 - 0.0066 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KDO30395.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KDO30395.1 - 0.03 14.3 0.0 0.075 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 KDO30395.1 - 0.039 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KDO30395.1 - 0.048 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KDO30395.1 - 0.058 12.6 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KDO30395.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KDO30395.1 - 0.071 13.5 0.1 0.69 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KDO30395.1 - 0.11 12.8 0.1 0.83 9.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO30395.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 KDO30395.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF5318 PF17249.2 KDO30395.1 - 0.16 11.8 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5318) p450 PF00067.22 KDO30395.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P450 TFIIS_M PF07500.14 KDO30397.1 - 6.1e-10 39.6 0.0 1.6e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PDZ_6 PF17820.1 KDO30397.1 - 0.0072 16.1 0.1 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO30397.1 - 0.013 15.8 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain LRR_6 PF13516.6 KDO30402.1 - 7.4e-08 31.8 7.1 0.0059 16.6 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KDO30402.1 - 0.00036 20.8 0.2 8.5 7.0 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO30402.1 - 0.036 13.8 3.3 0.6 9.9 0.0 3.9 4 2 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KDO30403.1 - 0.0018 18.6 4.9 0.15 12.5 1.4 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) DUF832 PF05734.11 KDO30403.1 - 0.041 13.4 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) LRR_8 PF13855.6 KDO30403.1 - 0.2 11.4 6.4 0.2 11.5 0.5 3.4 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KDO30403.1 - 1.6 9.6 3.8 4.6 8.2 1.9 2.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO30405.1 - 0.002 18.5 0.9 13 6.4 0.0 4.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO30406.1 - 3.5e-08 32.9 13.9 0.031 14.3 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 KDO30406.1 - 0.32 10.8 0.1 0.32 10.8 0.1 3.6 4 2 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KDO30406.1 - 0.74 10.3 7.2 2.2 8.8 0.1 3.7 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LpxC PF03331.13 KDO30407.1 - 0.0057 16.2 0.1 0.0079 15.7 0.1 1.2 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase LRR_6 PF13516.6 KDO30407.1 - 0.39 10.9 1.9 2.1e+02 2.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 KDO30408.1 - 0.19 11.2 0.0 0.81 9.2 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KDO30409.1 - 3.3e-10 39.2 12.5 0.00055 19.8 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KDO30409.1 - 0.04 13.4 0.4 0.21 11.1 0.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 KDO30409.1 - 1.7 8.4 7.7 0.94 9.3 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KDO30409.1 - 2.2 8.8 8.8 3.8 8.1 0.1 4.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) zf-RVT PF13966.6 KDO30410.1 - 2.8e-05 24.7 1.5 6.6e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FYVE PF01363.21 KDO30411.1 - 2.4 8.4 6.4 4.6 7.4 6.3 1.5 1 1 0 1 1 1 0 FYVE zinc finger Shugoshin_N PF07558.11 KDO30412.1 - 0.19 11.6 3.5 1.2 9.1 0.1 4.1 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region tRNA-synt_1c PF00749.21 KDO30413.1 - 8.7e-99 330.4 0.1 1.1e-98 330.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KDO30413.1 - 4e-35 121.2 0.0 6.3e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 KDO30413.1 - 2.7e-18 65.9 2.5 5.8e-18 64.8 2.5 1.6 1 0 0 1 1 1 1 WHEP-TRS domain GST_C_3 PF14497.6 KDO30413.1 - 4.1e-05 23.7 0.0 0.00049 20.3 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO30413.1 - 8.5e-05 22.7 0.1 0.00033 20.8 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO30413.1 - 0.00064 19.7 1.0 0.0016 18.4 1.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KDO30413.1 - 0.0015 18.0 0.1 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain PPR_1 PF12854.7 KDO30413.1 - 2 8.2 5.9 16 5.3 0.1 3.3 3 0 0 3 3 3 0 PPR repeat PX PF00787.24 KDO30414.1 - 5.8e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 PX domain DUF4326 PF14216.6 KDO30415.1 - 2.8e-20 72.8 0.0 5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) zf-RanBP PF00641.18 KDO30415.1 - 0.012 14.9 5.0 0.018 14.4 5.0 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others TMEM239 PF15841.5 KDO30416.1 - 0.0074 16.2 1.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Transmembrane protein 239 family Lentiviral_Tat PF02998.14 KDO30417.1 - 0.055 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Lentiviral Tat protein PUA_2 PF14306.6 KDO30419.1 - 0.04 13.6 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 PUA-like domain ABC_tran PF00005.27 KDO30420.1 - 1.2e-28 100.4 0.0 2.3e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO30420.1 - 7.7e-26 91.3 9.9 1.3e-25 90.6 9.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO30420.1 - 8.4e-08 31.9 0.7 8.7e-06 25.3 0.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO30420.1 - 0.00038 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KDO30420.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KDO30420.1 - 0.0028 17.4 0.2 0.0079 15.9 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO30420.1 - 0.011 16.0 0.5 0.14 12.5 0.5 2.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KDO30420.1 - 0.012 15.4 0.3 0.65 9.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KDO30420.1 - 0.018 14.6 0.1 0.62 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 KDO30420.1 - 0.042 12.7 0.2 0.46 9.2 0.1 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 KDO30420.1 - 0.044 14.2 1.5 11 6.5 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO30420.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KDO30420.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KDO30420.1 - 0.067 13.4 0.1 0.26 11.6 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane_2 PF06472.15 KDO30420.1 - 0.081 12.3 2.0 0.32 10.4 2.1 2.0 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 NACHT PF05729.12 KDO30420.1 - 0.089 12.7 0.1 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KDO30420.1 - 0.12 12.3 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain FeS PF04060.13 KDO30421.1 - 0.027 14.1 0.1 0.24 11.1 0.0 2.3 3 0 0 3 3 3 0 Putative Fe-S cluster DUF1726 PF08351.11 KDO30421.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Elicitin PF00964.17 KDO30422.1 - 0.0011 19.0 1.3 0.0016 18.5 0.0 1.9 2 1 0 2 2 2 1 Elicitin DUF1631 PF07793.11 KDO30422.1 - 0.36 9.2 1.1 0.4 9.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF5525 PF17663.1 KDO30422.1 - 2.5 6.0 20.1 2.9 5.8 20.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) SOG2 PF10428.9 KDO30422.1 - 4.7 6.3 13.9 6.2 5.9 13.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CRAL_TRIO_2 PF13716.6 KDO30423.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.7 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain RseC_MucC PF04246.12 KDO30423.1 - 0.038 13.9 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Sigma70_r3 PF04539.16 KDO30423.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 MarR_2 PF12802.7 KDO30423.1 - 0.14 12.1 0.1 0.69 9.9 0.0 2.2 2 1 1 3 3 3 0 MarR family HTH_11 PF08279.12 KDO30423.1 - 0.22 11.5 0.3 0.79 9.7 0.0 2.0 2 0 0 2 2 2 0 HTH domain OprD PF03573.13 KDO30427.1 - 0.0017 17.5 0.5 0.002 17.2 0.5 1.1 1 0 0 1 1 1 1 outer membrane porin, OprD family NnrU PF07298.11 KDO30427.1 - 0.13 11.8 0.4 0.17 11.4 0.4 1.2 1 0 0 1 1 1 0 NnrU protein TMEM247 PF15444.6 KDO30427.1 - 0.14 12.1 2.0 0.17 11.9 2.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Spt20 PF12090.8 KDO30427.1 - 0.51 9.9 8.0 0.6 9.7 8.0 1.2 1 0 0 1 1 1 0 Spt20 family Chordopox_A30L PF06015.12 KDO30428.1 - 0.11 12.3 0.7 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Ank_2 PF12796.7 KDO30430.1 - 3.9e-28 97.9 23.9 4.6e-06 27.1 1.0 6.3 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO30430.1 - 3.3e-17 62.3 19.5 0.037 14.3 0.2 9.7 7 3 5 12 12 12 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO30430.1 - 1.1e-16 61.0 22.1 0.0041 17.7 0.2 9.8 5 4 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30430.1 - 2.5e-12 45.8 9.6 4 8.3 0.0 10.7 10 1 1 11 11 11 2 Ankyrin repeat DUF5049 PF16468.5 KDO30430.1 - 3.2e-05 23.7 0.3 0.96 9.4 0.0 6.1 8 0 0 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 KDO30430.1 - 0.006 17.0 9.8 25 5.5 0.3 7.4 5 2 1 6 6 6 1 Ankyrin repeat Erythro-docking PF09277.11 KDO30430.1 - 4.2 7.4 5.1 13 5.8 0.7 3.7 3 1 1 4 4 4 0 Erythronolide synthase, docking DUF4807 PF16065.5 KDO30433.1 - 8e-11 41.7 1.0 1.3e-10 41.0 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) zf-RING_2 PF13639.6 KDO30434.1 - 2.3e-11 43.8 8.6 3.1e-11 43.4 7.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO30434.1 - 7.6e-11 41.7 8.8 1.5e-10 40.7 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO30434.1 - 1.2e-07 31.4 8.2 1.8e-07 30.9 7.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30434.1 - 1.6e-07 31.5 13.2 1.2e-06 28.6 12.6 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO30434.1 - 2.4e-05 24.2 5.3 5.6e-05 23.0 4.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KDO30434.1 - 7.4e-05 22.4 8.2 7.4e-05 22.4 8.2 2.4 3 1 0 3 3 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO30434.1 - 9.8e-05 22.3 6.8 9.8e-05 22.3 6.8 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO30434.1 - 0.00025 20.9 7.9 0.00046 20.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO30434.1 - 0.00032 20.7 7.4 0.0022 18.0 7.2 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KDO30434.1 - 0.0012 19.0 6.6 0.0027 17.8 6.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 KDO30434.1 - 1 9.6 12.5 0.19 11.9 7.7 1.8 1 1 1 2 2 2 0 Zinc-ribbon like family PHD PF00628.29 KDO30434.1 - 1.2 9.1 13.0 3.3 7.7 6.5 2.6 1 1 1 2 2 2 0 PHD-finger Prok-RING_4 PF14447.6 KDO30434.1 - 1.9 8.4 13.6 3.6 7.5 13.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO30434.1 - 6.5 6.5 13.0 9.6 5.9 11.5 2.0 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KDO30435.1 - 6e-05 23.6 0.1 0.00023 21.7 0.0 1.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30435.1 - 7.3e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO30435.1 - 0.03 14.8 1.2 0.12 12.9 0.1 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KDO30435.1 - 0.051 13.9 0.7 0.67 10.3 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF2371 PF10177.9 KDO30436.1 - 0.00036 20.7 1.8 0.24 11.6 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2371) V-set_CD47 PF08204.11 KDO30436.1 - 0.021 14.8 0.2 0.12 12.4 0.1 1.9 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain PIRT PF15099.6 KDO30436.1 - 0.47 10.0 5.4 5.2 6.6 4.4 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family TMEM174 PF15029.6 KDO30436.1 - 7 6.3 5.9 6.3 6.5 0.5 2.0 1 1 1 2 2 2 0 Transmembrane protein 174 Tfb2 PF03849.14 KDO30437.1 - 1.6e-112 376.0 0.2 2.1e-112 375.6 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KDO30437.1 - 4.2e-21 75.2 0.1 9.1e-20 70.9 0.2 2.7 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KDO30437.1 - 0.00066 19.8 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FAD_binding_6 PF00970.24 KDO30438.1 - 6.2e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KDO30438.1 - 3.8e-09 37.2 0.0 2.6e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KDO30438.1 - 3.2e-08 34.1 0.0 1.8e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KDO30438.1 - 7.7e-05 22.9 0.0 0.0021 18.2 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain SAM_DrpA PF18255.1 KDO30439.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain MutS_III PF05192.18 KDO30439.1 - 0.081 13.1 4.7 0.18 12.0 4.7 1.6 1 1 0 1 1 1 0 MutS domain III DUF2894 PF11445.8 KDO30439.1 - 0.95 9.9 8.8 0.54 10.7 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) ABC_tran_CTD PF16326.5 KDO30439.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.1 5 1 0 5 5 5 0 ABC transporter C-terminal domain DUF1690 PF07956.11 KDO30439.1 - 1.2 9.5 15.9 2.6 8.4 0.3 3.8 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) Gluconate_2-dh3 PF13618.6 KDO30439.1 - 3.4 7.9 5.9 30 4.8 5.9 2.3 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Sep15_SelM PF08806.11 KDO30440.1 - 2.1e-07 31.0 0.0 3.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain DND1_DSRM PF14709.7 KDO30440.1 - 0.043 14.1 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Hist_deacetyl PF00850.19 KDO30444.1 - 4.3e-82 276.0 0.6 5.3e-82 275.7 0.6 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pyridoxal_deC PF00282.19 KDO30445.1 - 4e-37 127.8 0.0 6.4e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KDO30445.1 - 0.00018 20.6 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KDO30445.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase FBPase PF00316.20 KDO30448.1 - 4.8e-56 189.2 0.1 7e-56 188.7 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Ax_dynein_light PF10211.9 KDO30449.1 - 5.1e-83 277.6 13.2 6.5e-83 277.3 13.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain GTP_EFTU_D3 PF03143.17 KDO30450.1 - 4.5e-30 104.2 0.5 4.5e-29 101.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KDO30450.1 - 3.3e-11 43.4 0.4 1.3e-10 41.5 0.2 2.1 2 1 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 KDO30450.1 - 3.2e-07 30.1 0.0 8.1e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 KDO30450.1 - 0.012 15.6 0.2 0.086 12.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 FbpC_C_terminal PF17845.1 KDO30450.1 - 0.1 12.7 0.1 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain DUF1744 PF08490.12 KDO30451.1 - 6.5e-78 262.1 0.0 3.3e-76 256.4 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KDO30451.1 - 4.6e-66 223.3 0.0 8.6e-66 222.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KDO30451.1 - 1.1e-17 64.0 1.6 4.4e-16 58.6 1.6 2.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KDO30451.1 - 1.1e-06 28.5 0.3 5e-06 26.3 0.3 2.1 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KDO30451.1 - 3.4e-05 23.9 0.0 0.0003 20.8 0.0 2.5 2 0 0 2 2 2 1 RNase_H superfamily CobD_Cbib PF03186.13 KDO30451.1 - 0.0046 16.2 0.0 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 CobD/Cbib protein Peptidase_C1 PF00112.23 KDO30452.1 - 9.3e-59 199.1 9.6 1.2e-58 198.8 9.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease PT PF04886.12 KDO30452.1 - 2.9e-27 93.9 66.2 1.8e+04 -14.9 64.2 4.9 1 1 0 1 1 1 0 PT repeat Peptidase_C1_2 PF03051.15 KDO30452.1 - 0.0044 15.9 2.0 0.048 12.4 0.2 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO30453.1 - 8.8e-51 173.1 7.4 1.2e-50 172.7 7.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease PT PF04886.12 KDO30453.1 - 4.1e-10 39.0 32.6 1.5e-05 24.5 20.3 2.4 1 1 1 2 2 2 2 PT repeat Peptidase_C1_2 PF03051.15 KDO30453.1 - 0.041 12.7 1.2 0.64 8.7 0.1 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Trypan_PARP PF05887.11 KDO30453.1 - 6.4 6.8 12.9 13 5.8 12.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.12 KDO30454.1 - 0.22 10.8 2.9 0.39 10.0 2.9 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KDO30454.1 - 0.76 9.5 8.8 0.54 10.0 6.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M1 PF01433.20 KDO30458.1 - 1.7e-11 44.1 0.3 4.6e-11 42.7 0.3 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain TsaE PF02367.17 KDO30459.1 - 1.6e-30 105.6 0.0 1.9e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KDO30459.1 - 8.1e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO30459.1 - 0.008 16.6 0.0 0.0098 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KDO30459.1 - 0.055 13.0 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO30459.1 - 0.08 13.1 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO30459.1 - 0.088 13.2 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 KDO30459.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KDO30459.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Tfb5 PF06331.12 KDO30460.1 - 2.2e-26 91.6 0.0 2.4e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 PLAC9 PF15205.6 KDO30462.1 - 0.032 14.6 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 RCC1 PF00415.18 KDO30466.1 - 1.3e-62 208.2 24.2 5.2e-15 55.8 0.1 8.4 6 3 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 KDO30466.1 - 5.9e-41 140.5 0.0 8.2e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RCC1_2 PF13540.6 KDO30466.1 - 3.6e-28 96.7 34.0 5.6e-09 35.6 0.4 7.7 7 1 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PX PF00787.24 KDO30466.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 PX domain SnoaL_2 PF12680.7 KDO30468.1 - 0.13 12.9 0.5 0.37 11.4 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain PI-PLC-X PF00388.19 KDO30470.1 - 5.8e-59 197.8 0.0 1.1e-58 197.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KDO30470.1 - 3.6e-36 124.0 0.1 1.1e-35 122.5 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KDO30470.1 - 1e-14 54.6 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KDO30470.1 - 2.9e-07 30.8 0.0 7.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO30470.1 - 4.8e-07 28.9 0.0 0.0012 18.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KDO30470.1 - 0.0002 20.7 0.1 1 8.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO30470.1 - 0.00078 19.2 0.0 0.66 10.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KDO30470.1 - 0.0017 18.3 0.1 0.011 15.7 0.1 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KDO30470.1 - 0.0047 17.2 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region PH_12 PF16457.5 KDO30470.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_8 PF13833.6 KDO30470.1 - 0.018 14.9 0.2 0.56 10.1 0.1 3.0 4 0 0 4 4 4 0 EF-hand domain pair Hemerythrin PF01814.23 KDO30471.1 - 0.022 15.4 0.5 1.3 9.6 0.2 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Peptidase_S10 PF00450.22 KDO30472.1 - 3.9e-114 382.3 0.0 4.9e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PGF-CTERM PF18204.1 KDO30472.1 - 0.28 11.2 18.3 0.55 10.3 3.8 2.7 2 0 0 2 2 2 0 PGF-CTERM motif Peptidase_S10 PF00450.22 KDO30473.1 - 5e-123 411.6 0.0 6.2e-123 411.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KDO30474.1 - 4.1e-117 392.1 0.0 4.6e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KDO30475.1 - 3.5e-119 398.9 0.0 4.1e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4381 PF14316.6 KDO30475.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM100 PF16311.5 KDO30475.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 Peptidase_S10 PF00450.22 KDO30476.1 - 3.3e-119 399.0 0.0 3.9e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase TPPK_C PF12555.8 KDO30476.1 - 0.14 12.2 3.3 4.9 7.3 0.6 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal SET PF00856.28 KDO30477.1 - 8e-10 39.4 0.1 2.2e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 KDO30477.1 - 0.0095 16.2 0.2 0.024 14.9 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 KDO30477.1 - 0.065 13.7 0.3 0.24 11.9 0.3 2.0 1 0 0 1 1 1 0 Zinc-finger double domain SAF PF08666.12 KDO30477.1 - 0.11 13.2 0.6 1.8 9.3 0.0 3.2 4 0 0 4 4 4 0 SAF domain SET PF00856.28 KDO30478.1 - 4.5e-06 27.2 0.2 2e-05 25.1 0.1 2.1 2 1 0 2 2 2 1 SET domain TPR_8 PF13181.6 KDO30478.1 - 0.011 15.9 0.2 0.03 14.5 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO30478.1 - 0.023 15.0 0.2 0.058 13.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Actin PF00022.19 KDO30479.1 - 1.6e-54 185.1 0.0 2.7e-53 181.1 0.0 2.5 1 1 0 1 1 1 1 Actin HrpF PF06266.12 KDO30479.1 - 0.099 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 HrpF protein MreB_Mbl PF06723.13 KDO30479.1 - 0.15 10.8 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein RRM_1 PF00076.22 KDO30480.1 - 3.5e-18 65.2 0.0 5.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO30480.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Elicitin PF00964.17 KDO30481.1 - 7e-06 26.1 0.1 1.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Elicitin Peptidase_M20 PF01546.28 KDO30482.1 - 1.8e-21 76.8 0.2 3e-21 76.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO30482.1 - 1.3e-07 31.5 0.2 4.6e-07 29.7 0.2 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain U-box PF04564.15 KDO30483.1 - 2e-22 79.1 0.0 3.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KDO30483.1 - 2.7e-16 58.6 6.6 8.5e-07 28.5 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30483.1 - 3.4e-12 45.8 2.0 2.4e-06 27.1 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 KDO30483.1 - 9.3e-12 44.1 7.2 0.00019 21.3 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO30483.1 - 1.2e-05 25.6 3.2 0.0066 16.7 2.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30483.1 - 3.1e-05 23.9 7.7 0.043 14.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO30483.1 - 8e-05 23.2 1.6 0.00099 19.7 1.1 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO30483.1 - 0.00016 21.8 3.1 0.00016 21.8 3.1 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KDO30483.1 - 0.00066 19.9 2.1 0.81 10.2 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO30483.1 - 0.0028 18.1 1.7 0.025 15.1 1.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 KDO30483.1 - 0.0074 16.3 0.7 0.79 9.8 0.1 2.8 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 KDO30483.1 - 0.015 15.4 2.1 0.031 14.4 0.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30483.1 - 0.02 15.7 0.2 7.5 7.7 0.0 3.3 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30483.1 - 0.024 14.6 2.5 1.8 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO30483.1 - 0.4 11.4 4.0 26 5.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SET PF00856.28 KDO30484.1 - 5.9e-07 30.0 1.3 1.6e-06 28.6 0.6 2.0 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 KDO30484.1 - 0.032 14.5 0.1 0.073 13.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30484.1 - 0.18 12.0 0.6 0.93 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30484.1 - 0.36 11.2 0.2 0.36 11.2 0.2 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SET PF00856.28 KDO30485.1 - 1.3e-07 32.2 0.0 3.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 SET domain TPR_2 PF07719.17 KDO30485.1 - 0.014 15.5 0.1 0.062 13.4 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO30485.1 - 0.018 14.9 1.7 0.075 12.9 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30485.1 - 0.11 12.8 0.1 0.36 11.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RVT_1 PF00078.27 KDO30486.1 - 1.2e-06 28.2 0.0 1.3e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.23 KDO30490.1 - 1.3e-63 214.8 0.3 2.4e-63 214.0 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO30490.1 - 2.5e-15 56.8 0.0 7e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 KDO30490.1 - 6.6e-13 48.8 9.0 1e-12 48.2 6.7 2.6 1 1 1 2 2 2 1 HSA ResIII PF04851.15 KDO30490.1 - 3.5e-08 33.6 0.0 8.9e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit F-box-like PF12937.7 KDO30490.1 - 3.2e-05 23.7 1.0 6.7e-05 22.7 0.3 2.0 2 0 0 2 2 2 1 F-box-like Beta_helix PF13229.6 KDO30490.1 - 6.6e-05 22.8 0.6 0.00013 21.8 0.3 1.6 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KDO30490.1 - 0.00056 19.2 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DEAD PF00270.29 KDO30490.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase WW PF00397.26 KDO30490.1 - 0.012 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 WW domain Pyr_redox PF00070.27 KDO30490.1 - 0.028 14.9 0.2 0.099 13.2 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mst1_SARAH PF11629.8 KDO30490.1 - 0.1 12.7 6.6 7.9 6.6 0.3 3.8 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 AAA_14 PF13173.6 KDO30490.1 - 0.14 12.2 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Flavi_NS2B PF01002.19 KDO30490.1 - 0.19 11.6 1.1 0.59 10.0 1.1 1.8 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B CbiC PF02570.15 KDO30491.1 - 0.052 13.2 0.2 0.095 12.3 0.1 1.6 2 0 0 2 2 2 0 Precorrin-8X methylmutase Pkinase PF00069.25 KDO30492.1 - 3.2e-68 230.0 0.0 4e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30492.1 - 5.8e-36 124.1 0.0 7.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO30492.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO30492.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO30492.1 - 0.0077 15.0 0.0 0.13 11.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KDO30492.1 - 0.0077 16.2 0.2 0.33 10.9 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KDO30492.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KDO30492.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 KDO30492.1 - 0.21 10.5 0.0 1 8.2 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Spc29 PF17082.5 KDO30493.1 - 0.0085 16.0 1.5 0.012 15.5 0.1 1.8 2 0 0 2 2 2 1 Spindle Pole Component 29 GatB_Yqey PF02637.18 KDO30493.1 - 0.014 15.3 3.8 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 GatB domain FOP_dimer PF09398.10 KDO30493.1 - 0.16 12.2 0.5 0.38 11.0 0.5 1.6 1 0 0 1 1 1 0 FOP N terminal dimerisation domain MbeB_N PF04837.12 KDO30493.1 - 1.4 9.3 6.2 14 6.1 0.1 2.9 3 0 0 3 3 3 0 MbeB-like, N-term conserved region PfkB PF00294.24 KDO30494.1 - 0.06 12.6 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 pfkB family carbohydrate kinase CAP_GLY PF01302.25 KDO30495.1 - 5.2e-20 71.2 0.0 6.2e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 CAP-Gly domain Pkinase PF00069.25 KDO30496.1 - 1.2e-30 106.8 0.0 1.5e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30496.1 - 3.5e-29 101.9 0.0 5.8e-29 101.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO30496.1 - 3.6e-05 23.2 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HalOD1 PF18545.1 KDO30496.1 - 0.052 13.8 0.0 0.6 10.4 0.0 2.5 2 1 1 3 3 3 0 Halobacterial output domain 1 DUF1450 PF07293.11 KDO30496.1 - 0.16 11.8 0.1 0.85 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) FYVE PF01363.21 KDO30497.1 - 0.00083 19.5 5.6 0.0011 19.1 5.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger GluR_Homer-bdg PF10606.9 KDO30497.1 - 0.02 15.1 1.0 0.02 15.1 1.0 2.2 3 0 0 3 3 3 0 Homer-binding domain of metabotropic glutamate receptor FYVE_2 PF02318.16 KDO30497.1 - 0.1 12.9 4.8 0.16 12.2 4.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 KDO30497.1 - 4.9 7.4 6.6 12 6.1 6.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain tRNA-synt_1c PF00749.21 KDO30498.1 - 7e-96 320.8 0.9 5.1e-95 318.0 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KDO30498.1 - 9.9e-34 116.7 0.0 2e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KDO30498.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain WD40 PF00400.32 KDO30499.1 - 2.3e-25 88.4 16.2 1.9e-05 25.3 0.3 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30499.1 - 2.9e-13 49.9 0.4 0.00041 20.6 0.1 5.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KDO30499.1 - 4.1e-05 22.8 0.1 0.0064 15.6 0.0 3.0 2 1 1 3 3 3 1 VID27 C-terminal WD40-like domain TPR_11 PF13414.6 KDO30499.1 - 0.00015 21.4 0.0 0.00058 19.5 0.0 2.0 1 1 1 2 2 2 1 TPR repeat ATG16 PF08614.11 KDO30499.1 - 0.00021 21.6 20.1 0.00021 21.6 20.1 2.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) TPR_2 PF07719.17 KDO30499.1 - 0.008 16.2 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30499.1 - 0.054 13.3 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PQQ_3 PF13570.6 KDO30499.1 - 0.064 13.8 1.6 2.1 9.0 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Nup160 PF11715.8 KDO30499.1 - 0.33 9.5 2.2 11 4.5 0.0 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 KDO30499.1 - 1.3 10.0 0.0 1.3 10.0 0.0 3.6 3 1 1 4 4 2 0 Tetratricopeptide repeat FAM76 PF16046.5 KDO30499.1 - 2.6 7.3 21.2 4 6.7 21.2 1.2 1 0 0 1 1 1 0 FAM76 protein Fe-S_biosyn PF01521.20 KDO30500.1 - 8.9e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-RING_2 PF13639.6 KDO30501.1 - 6e-13 48.9 5.4 6e-13 48.9 5.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO30501.1 - 2.5e-10 40.0 6.3 2.5e-10 40.0 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO30501.1 - 1.8e-09 37.3 3.8 1.8e-09 37.3 3.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30501.1 - 6.3e-09 36.0 6.3 1.5e-08 34.8 6.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO30501.1 - 2.1e-08 33.9 4.7 2.1e-08 33.9 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO30501.1 - 2.1e-08 34.1 1.5 2.1e-08 34.1 1.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO30501.1 - 7.7e-08 32.1 4.6 2.3e-07 30.6 4.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KDO30501.1 - 2.9e-07 30.1 2.6 2.9e-07 30.1 2.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KDO30501.1 - 2.6e-06 27.5 3.6 0.00012 22.2 1.0 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO30501.1 - 0.00061 19.7 4.9 0.00061 19.7 4.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KDO30501.1 - 0.00079 19.0 3.8 0.0019 17.8 3.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KDO30501.1 - 0.011 15.8 6.0 0.032 14.3 6.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 KDO30501.1 - 0.04 14.1 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 U-box domain RINGv PF12906.7 KDO30501.1 - 0.23 11.6 4.9 0.56 10.4 4.9 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KDO30501.1 - 0.35 10.9 8.2 0.58 10.2 5.3 2.6 1 1 1 2 2 2 0 Zinc-finger FANCL_C PF11793.8 KDO30501.1 - 0.46 10.7 5.6 6.3 7.1 5.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KDO30501.1 - 1.1 9.6 4.9 2.6 8.4 4.9 1.7 1 1 0 1 1 1 0 RING-like domain zf-RING_6 PF14835.6 KDO30501.1 - 1.9 8.4 7.1 1.4 8.8 3.0 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KDO30501.1 - 9.5 6.1 7.1 3.9 7.4 4.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KDO30502.1 - 2.9e-13 49.9 3.6 4.6e-13 49.3 3.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO30502.1 - 4.5e-12 45.6 4.3 8.6e-12 44.7 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30502.1 - 1.8e-10 40.9 1.8 3.1e-10 40.2 1.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KDO30502.1 - 4e-08 32.8 1.9 4e-08 32.8 1.9 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO30502.1 - 5.7e-08 32.6 3.0 8.8e-08 32.0 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO30502.1 - 3.2e-07 30.2 0.8 8.9e-07 28.8 0.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO30502.1 - 3e-06 27.2 1.2 5e-06 26.5 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO30502.1 - 4.8e-06 26.3 2.4 7.3e-06 25.7 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO30502.1 - 6e-06 25.8 4.9 1.2e-05 24.8 4.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KDO30502.1 - 2.8e-05 23.9 3.0 5.2e-05 23.0 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO30502.1 - 0.00023 20.9 4.7 0.0004 20.2 4.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KDO30502.1 - 0.0068 16.5 1.8 0.012 15.8 1.8 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KDO30502.1 - 0.023 14.9 3.2 0.023 14.9 3.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 KDO30502.1 - 0.032 14.4 1.1 0.037 14.2 0.2 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 KDO30502.1 - 0.038 13.9 4.2 0.24 11.4 1.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 KDO30502.1 - 0.047 13.8 2.1 0.11 12.6 2.1 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO30502.1 - 0.048 13.8 4.7 0.19 12.0 4.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain LIM PF00412.22 KDO30502.1 - 0.083 13.1 2.0 0.2 11.9 2.0 1.6 1 1 0 1 1 1 0 LIM domain zf-RING-like PF08746.11 KDO30502.1 - 0.12 12.7 3.5 0.21 11.9 3.5 1.4 1 0 0 1 1 1 0 RING-like domain Vps39_2 PF10367.9 KDO30502.1 - 0.14 12.6 0.4 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.6 KDO30502.1 - 0.2 11.5 3.3 0.48 10.3 2.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KDO30502.1 - 0.4 10.7 3.8 1 9.5 3.8 1.7 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 KDO30502.1 - 0.87 9.5 4.6 1.9 8.4 4.6 1.6 1 0 0 1 1 1 0 PHD-finger Tmpp129 PF10272.9 KDO30502.1 - 2.6 7.3 5.7 0.5 9.6 1.2 1.9 1 1 1 2 2 2 0 Putative transmembrane protein precursor Clat_adaptor_s PF01217.20 KDO30504.1 - 0.0054 16.7 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AvrB_AvrC PF05394.11 KDO30504.1 - 0.088 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Avirulence protein NIF PF03031.18 KDO30506.1 - 1.2e-24 86.9 0.1 4.1e-24 85.1 0.1 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KDO30506.1 - 5.6e-06 26.0 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KDO30506.1 - 0.0025 18.2 0.0 0.0059 17.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain WD40 PF00400.32 KDO30507.1 - 1.2e-19 70.3 7.4 0.00033 21.4 1.0 5.7 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30507.1 - 9.1e-17 61.1 0.0 0.0002 21.6 0.0 5.2 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO30507.1 - 1.7e-05 23.9 0.2 0.0011 18.0 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KDO30507.1 - 0.0029 17.0 0.0 0.16 11.2 0.0 2.9 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 KDO30507.1 - 0.039 12.6 0.0 5 5.6 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.11 KDO30507.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF4131 PF13567.6 KDO30508.1 - 0.13 11.9 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MMS1_N PF10433.9 KDO30510.1 - 6.4e-138 460.4 0.0 8.6e-138 460.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KDO30510.1 - 1.7e-25 90.0 0.0 7.6e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region TBPIP_N PF15517.6 KDO30510.1 - 0.097 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 TBP-interacting protein N-terminus DUF2761 PF10959.8 KDO30510.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) GSP_synth PF03738.14 KDO30511.1 - 8.1e-54 183.2 0.0 1.1e-53 182.8 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp RVT_2 PF07727.14 KDO30512.1 - 7.3e-27 94.6 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CotH PF08757.11 KDO30513.1 - 3.3e-32 112.3 0.2 2.6e-31 109.4 0.2 1.9 1 1 0 1 1 1 1 CotH kinase protein Esterase PF00756.20 KDO30514.1 - 3e-19 69.6 0.0 2.6e-17 63.3 0.0 2.0 1 1 1 2 2 2 2 Putative esterase FPP PF05911.11 KDO30515.1 - 0.0013 17.0 3.4 0.002 16.4 3.4 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KDO30515.1 - 0.0076 16.3 10.5 0.056 13.5 5.3 2.7 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KDO30515.1 - 0.055 12.1 5.1 0.09 11.4 3.1 1.8 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 KDO30515.1 - 0.11 11.5 10.6 0.027 13.6 6.8 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KDO30515.1 - 0.11 12.9 8.4 0.67 10.4 8.4 2.1 1 1 0 1 1 1 0 Fez1 HAP1_N PF04849.13 KDO30515.1 - 0.15 11.3 9.8 0.13 11.5 7.2 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region CCDC144C PF14915.6 KDO30515.1 - 0.19 10.8 10.9 0.52 9.4 10.9 1.7 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region OmpH PF03938.14 KDO30515.1 - 0.34 11.3 9.2 1.1 9.6 6.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cnn_1N PF07989.11 KDO30515.1 - 0.34 11.1 6.0 5.7 7.2 3.1 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 COG2 PF06148.11 KDO30515.1 - 0.4 10.8 7.4 2.9 8.0 0.1 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF724 PF05266.14 KDO30515.1 - 0.6 9.9 7.1 2 8.2 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PI3K_P85_iSH2 PF16454.5 KDO30515.1 - 0.66 9.6 10.4 0.53 9.9 7.9 2.0 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Golgin_A5 PF09787.9 KDO30515.1 - 0.72 9.3 11.3 0.39 10.1 8.8 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 KDO30515.1 - 1.4 9.2 8.0 11 6.3 5.9 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1043 PF06295.12 KDO30515.1 - 1.8 8.6 8.0 3.1 7.8 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DHR10 PF18595.1 KDO30515.1 - 2.4 8.2 18.3 3 7.9 13.2 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain TPR_MLP1_2 PF07926.12 KDO30515.1 - 2.8 8.0 18.9 7.7 6.6 12.3 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.11 KDO30515.1 - 3.1 8.1 9.5 40 4.5 0.0 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 KDO30515.1 - 5.4 7.2 11.9 3.7 7.7 8.4 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase RhoGAP PF00620.27 KDO30518.1 - 4.1e-16 59.2 0.0 6.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KDO30518.1 - 0.0017 18.8 0.0 0.0073 16.8 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_16 PF17838.1 KDO30518.1 - 0.045 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 KDO30518.1 - 0.083 13.2 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 KDO30518.1 - 0.18 12.2 0.0 0.62 10.5 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Sugar_tr PF00083.24 KDO30519.1 - 1e-31 110.3 20.5 4.3e-26 91.8 6.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO30519.1 - 1.4e-24 86.7 29.3 1.9e-24 86.3 29.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KDO30519.1 - 0.0015 17.2 6.8 0.0015 17.2 6.8 2.4 1 1 0 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 KDO30519.1 - 0.0016 16.8 0.5 0.0032 15.8 0.5 1.5 1 0 0 1 1 1 1 BT1 family Prenylcys_lyase PF07156.14 KDO30519.1 - 0.17 11.0 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase DUF4293 PF14126.6 KDO30519.1 - 0.23 11.7 9.8 0.078 13.2 3.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) GMC_oxred_N PF00732.19 KDO30520.1 - 1.3e-42 146.2 0.0 1.8e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KDO30520.1 - 7.5e-24 84.9 0.5 1.5e-23 84.0 0.5 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KDO30520.1 - 0.02 14.0 0.4 0.039 13.0 0.4 1.4 1 1 0 1 1 1 0 FAD binding domain GFA PF04828.14 KDO30523.1 - 2.2e-07 31.1 2.6 2.2e-07 31.1 2.6 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PLAC8 PF04749.17 KDO30524.1 - 1.2e-17 64.7 23.3 3e-17 63.4 23.3 1.6 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KDO30525.1 - 3.6e-19 69.6 12.2 5.8e-19 68.9 12.2 1.3 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KDO30526.1 - 1.7e-20 73.9 16.4 2.9e-20 73.1 16.4 1.4 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KDO30527.1 - 0.0035 18.3 7.1 0.0043 18.0 7.1 1.3 1 1 0 1 1 1 1 PLAC8 family Kinocilin PF15033.6 KDO30527.1 - 1.4 8.6 4.0 1.6 8.4 4.0 1.1 1 0 0 1 1 1 0 Kinocilin protein APP_E2 PF12925.7 KDO30528.1 - 0.063 13.0 0.0 0.073 12.8 0.0 1.0 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Peptidase_C69 PF03577.15 KDO30529.1 - 5.2e-11 42.1 0.0 7.3e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 DUF997 PF06196.12 KDO30529.1 - 0.083 12.9 0.2 0.083 12.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Peptidase_C69 PF03577.15 KDO30530.1 - 2e-45 155.4 0.2 2.8e-44 151.6 0.2 2.1 1 1 0 1 1 1 1 Peptidase family C69 Peptidase_C69 PF03577.15 KDO30531.1 - 2.4e-31 109.1 2.9 3.5e-30 105.2 2.9 2.6 1 1 0 1 1 1 1 Peptidase family C69 AAA PF00004.29 KDO30532.1 - 2.5e-46 157.4 0.0 1.1e-40 139.1 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KDO30532.1 - 2.5e-20 72.3 0.1 6.1e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.6 KDO30532.1 - 3.2e-09 37.4 0.0 8.7e-06 26.2 0.0 3.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 KDO30532.1 - 2e-08 33.9 0.1 8.1e-08 31.9 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KDO30532.1 - 2.4e-08 34.3 0.1 0.14 12.4 0.1 5.0 3 2 1 4 4 4 2 AAA domain AAA_2 PF07724.14 KDO30532.1 - 3.4e-06 27.3 0.0 7.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KDO30532.1 - 3.6e-06 26.8 0.0 5.5e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.14 KDO30532.1 - 0.0017 18.4 0.0 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KDO30532.1 - 0.0041 17.5 0.0 0.031 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.6 KDO30532.1 - 0.0074 16.4 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KDO30532.1 - 0.0088 15.6 0.1 0.14 11.7 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region DUF815 PF05673.13 KDO30532.1 - 0.01 15.0 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KDO30532.1 - 0.011 15.4 0.0 0.69 9.6 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KDO30532.1 - 0.013 15.6 0.0 0.093 12.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KDO30532.1 - 0.02 14.6 0.0 0.088 12.6 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KDO30532.1 - 0.021 15.4 0.0 0.097 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KDO30532.1 - 0.032 13.6 0.3 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KDO30532.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KDO30532.1 - 0.044 14.0 3.0 0.15 12.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KDO30532.1 - 0.053 14.0 0.2 3.5 8.1 0.0 3.0 3 1 0 3 3 2 0 ABC transporter C1_2 PF03107.16 KDO30532.1 - 0.14 12.5 1.4 0.31 11.4 1.4 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KDO30532.1 - 0.16 11.9 8.8 0.3 11.0 7.2 2.2 2 0 0 2 2 2 0 PHD-finger TIP49 PF06068.13 KDO30532.1 - 0.2 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain C1_1 PF00130.22 KDO30532.1 - 2.9 7.9 6.1 6.2 6.8 6.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KDO30533.1 - 2.3e-16 60.0 0.0 3.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30533.1 - 1.6e-15 57.1 0.0 1.1e-14 54.3 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KDO30533.1 - 0.0039 16.6 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PLATZ PF04640.14 KDO30534.1 - 0.019 15.6 0.6 0.031 14.9 0.6 1.4 1 0 0 1 1 1 0 PLATZ transcription factor zf-MYND PF01753.18 KDO30534.1 - 0.28 11.3 4.1 0.53 10.4 4.1 1.5 1 1 0 1 1 1 0 MYND finger PDZ_2 PF13180.6 KDO30535.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO30535.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KDO30535.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 KDO30536.1 - 8.9e-44 149.8 0.0 1.1e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30536.1 - 8.7e-31 107.1 0.0 9.7e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO30536.1 - 0.00021 20.2 0.0 0.00029 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO30536.1 - 0.00059 19.2 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO30536.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLAC8 PF04749.17 KDO30537.1 - 3.3e-19 69.7 15.4 4.3e-19 69.3 15.4 1.1 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.17 KDO30538.1 - 2.4e-50 171.2 0.0 3.1e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30538.1 - 4.5e-50 170.5 0.0 5.9e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO30538.1 - 0.00032 20.1 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRIMA1 PF16101.5 KDO30538.1 - 0.006 16.6 0.0 0.071 13.1 0.1 2.3 3 0 0 3 3 3 1 Proline-rich membrane anchor 1 APH PF01636.23 KDO30538.1 - 0.0067 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO30538.1 - 0.0072 15.1 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO30538.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Crystall PF00030.19 KDO30538.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin RcbX PF02341.15 KDO30538.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 RbcX protein Haspin_kinase PF12330.8 KDO30538.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Inhibitor_I36 PF03995.13 KDO30538.1 - 0.18 11.8 0.1 6.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Pkinase PF00069.25 KDO30539.1 - 7.9e-34 117.2 0.0 4.3e-24 85.3 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30539.1 - 2.1e-31 109.1 0.0 1.3e-19 70.5 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO30539.1 - 0.05 12.9 0.0 0.095 12.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KDO30539.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO30539.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GRDP-like PF07173.12 KDO30540.1 - 1.3e-08 35.6 0.2 2.5e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like DZR PF12773.7 KDO30540.1 - 0.08 13.0 2.6 0.69 10.0 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pkinase_Tyr PF07714.17 KDO30541.1 - 4.9e-31 107.9 0.0 6.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30541.1 - 7.3e-22 78.0 0.0 9.1e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.15 KDO30541.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kdo PF06293.14 KDO30541.1 - 0.02 14.2 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_gE PF02480.16 KDO30541.1 - 0.021 13.6 0.6 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KDO30541.1 - 0.13 13.2 0.0 0.21 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GSP_synth PF03738.14 KDO30542.1 - 5.6e-61 206.8 0.0 8.3e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 KDO30542.1 - 6.6e-07 29.8 0.0 2.2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 CHAP domain GSP_synth PF03738.14 KDO30544.1 - 3.4e-55 187.7 0.0 1.1e-54 186.0 0.0 1.7 1 1 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 KDO30544.1 - 1.8e-08 34.8 0.0 4.3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 CHAP domain Mpv17_PMP22 PF04117.12 KDO30545.1 - 7.2e-07 29.3 0.8 1.2e-06 28.7 0.1 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ank_2 PF12796.7 KDO30546.1 - 3.1e-37 127.0 9.8 1.8e-15 57.3 1.8 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30546.1 - 5.1e-31 106.6 3.4 8.2e-08 32.6 0.1 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO30546.1 - 4.9e-28 96.3 14.4 0.00039 20.7 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KDO30546.1 - 8.9e-28 93.3 5.0 0.0023 18.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KDO30546.1 - 2.1e-26 91.6 16.9 3.4e-09 36.8 0.7 7.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) DZR PF12773.7 KDO30546.1 - 0.00041 20.3 6.5 0.00073 19.5 6.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon Cytochrom_c3_2 PF14537.6 KDO30546.1 - 0.024 15.1 0.9 0.047 14.2 0.9 1.5 1 0 0 1 1 1 0 Cytochrome c3 BNIP3 PF06553.12 KDO30546.1 - 0.21 11.3 0.8 6.6 6.4 0.0 2.5 2 1 0 2 2 2 0 BNIP3 Ank_4 PF13637.6 KDO30547.1 - 4.2e-37 126.1 3.0 1.4e-11 44.7 0.0 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30547.1 - 1.9e-35 121.3 6.7 3.9e-17 62.6 0.4 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO30547.1 - 2.3e-30 104.3 14.7 3.6e-08 33.5 0.3 6.0 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30547.1 - 2.4e-30 101.2 5.5 7.8e-05 22.8 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KDO30547.1 - 8.8e-27 92.3 18.7 9.9e-05 22.6 0.3 7.0 7 0 0 7 7 7 6 Ankyrin repeat UL11 PF11094.8 KDO30548.1 - 0.064 13.2 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Membrane-associated tegument protein DUF2807 PF10988.8 KDO30549.1 - 7.7e-17 61.7 4.9 6.2e-14 52.2 4.9 2.2 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain F-box-like PF12937.7 KDO30551.1 - 0.00017 21.4 0.0 0.00046 20.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO30551.1 - 0.0019 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain MutS_V PF00488.21 KDO30552.1 - 1.9e-76 256.3 0.8 3.3e-76 255.5 0.8 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KDO30552.1 - 4.6e-35 120.3 0.0 1.2e-34 119.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KDO30552.1 - 1.6e-32 113.3 0.9 9.6e-32 110.8 0.7 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KDO30552.1 - 3e-11 43.5 0.0 6.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KDO30552.1 - 1.8e-06 28.2 0.0 6.4e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KDO30552.1 - 0.028 14.0 0.0 0.36 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KDO30553.1 - 1e-95 320.6 21.4 3.3e-49 168.0 5.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO30553.1 - 6.7e-67 224.2 0.0 1.7e-32 112.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO30553.1 - 1.3e-10 41.1 2.5 0.0031 17.0 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO30553.1 - 1.7e-07 31.8 1.5 0.02 15.3 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO30553.1 - 4.6e-07 29.5 1.2 0.027 14.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO30553.1 - 6.3e-06 26.5 0.4 0.22 11.8 0.0 3.3 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KDO30553.1 - 2.2e-05 23.8 0.3 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin G-alpha PF00503.20 KDO30553.1 - 4e-05 23.0 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 KDO30553.1 - 0.00013 21.7 4.1 0.35 10.6 1.0 3.3 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KDO30553.1 - 0.00022 21.4 0.8 0.7 9.9 0.2 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 KDO30553.1 - 0.00037 20.3 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO30553.1 - 0.00037 20.4 0.4 1.1 9.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KDO30553.1 - 0.00064 20.0 0.4 0.59 10.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KDO30553.1 - 0.0011 18.7 0.0 0.82 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KDO30553.1 - 0.0039 16.0 5.7 0.35 9.6 0.1 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KDO30553.1 - 0.0041 17.0 1.6 2.3 8.0 0.1 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KDO30553.1 - 0.0072 16.5 3.5 6.4 7.1 0.2 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KDO30553.1 - 0.013 16.1 0.2 0.68 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO30553.1 - 0.014 14.9 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KDO30553.1 - 0.017 14.3 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 KDO30553.1 - 0.029 14.3 0.4 7.2 6.5 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KDO30553.1 - 0.033 14.3 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KDO30553.1 - 0.036 13.7 2.2 12 5.4 0.0 3.5 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KDO30553.1 - 0.038 13.6 3.1 0.44 10.1 0.0 3.0 4 0 0 4 4 2 0 AAA domain Pox_A32 PF04665.12 KDO30553.1 - 0.039 13.4 0.7 8.4 5.8 0.1 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein APS_kinase PF01583.20 KDO30553.1 - 0.041 13.8 0.4 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KDO30553.1 - 0.051 13.7 0.8 6.6 6.9 0.1 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KDO30553.1 - 0.051 13.6 1.2 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KDO30553.1 - 0.058 12.7 0.8 6.7 6.0 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KDO30553.1 - 0.089 13.2 0.5 12 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KDO30553.1 - 0.094 12.5 0.3 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 KDO30553.1 - 0.11 12.1 0.1 15 5.1 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 KDO30553.1 - 0.18 11.5 0.4 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KDO30553.1 - 0.29 11.6 0.8 21 5.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KDO30554.1 - 0.017 16.0 5.2 3.4 8.7 0.3 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat GFA PF04828.14 KDO30555.1 - 0.00015 22.0 0.0 0.0004 20.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 KDO30555.1 - 0.032 14.4 0.5 0.1 12.8 0.5 1.8 1 0 0 1 1 1 0 Ribosomal protein L37e DcpS_C PF11969.8 KDO30556.1 - 7.4e-17 61.9 5.2 1.1e-16 61.3 5.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KDO30556.1 - 1.1e-09 38.8 5.5 2.3e-09 37.9 5.5 1.5 1 0 0 1 1 1 1 HIT domain Thioredoxin PF00085.20 KDO30557.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4498 PF14926.6 KDO30558.1 - 1.8e-60 204.3 0.0 2e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Ank_5 PF13857.6 KDO30559.1 - 1.4e-21 76.2 19.8 0.016 15.6 0.0 10.1 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30559.1 - 7.8e-21 74.5 6.1 3.2e-07 30.9 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30559.1 - 1.8e-19 69.8 17.9 0.00019 22.0 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30559.1 - 9.4e-08 31.8 12.1 11 6.9 0.0 8.7 8 1 1 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 KDO30559.1 - 5.1e-05 23.1 0.1 3.5 7.6 0.0 6.1 4 2 4 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 KDO30559.1 - 0.17 12.4 12.1 31 5.2 0.7 6.2 3 3 1 4 4 4 0 Ankyrin repeat ArsC PF03960.15 KDO30560.1 - 0.12 12.4 0.0 6.4 6.9 0.0 3.4 2 0 0 2 2 2 0 ArsC family Nbl1_Borealin_N PF10444.9 KDO30560.1 - 2.2 8.0 13.5 5.8 6.6 0.0 7.2 6 0 0 6 6 6 0 Nbl1 / Borealin N terminal MaoC_dehydratas PF01575.19 KDO30561.1 - 7.3e-22 77.2 0.1 1.1e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KDO30561.1 - 1.3e-08 35.1 0.0 2.4e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KDO30561.1 - 0.0029 17.9 0.2 0.018 15.4 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily CybS PF05328.12 KDO30562.1 - 4.5e-11 42.6 0.1 6.7e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Csa1 PF06023.12 KDO30562.1 - 0.15 11.3 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Thioredoxin PF00085.20 KDO30563.1 - 9.5e-61 202.2 3.1 1.9e-29 101.7 0.1 3.4 4 1 1 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 KDO30563.1 - 5e-34 117.8 3.9 1.1e-25 90.6 0.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KDO30563.1 - 7.8e-12 45.6 2.8 0.00018 21.9 0.1 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KDO30563.1 - 1.2e-10 41.4 0.1 0.0006 19.7 0.0 3.5 2 1 1 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 KDO30563.1 - 1.1e-09 38.1 0.1 0.00071 19.0 0.0 2.5 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KDO30563.1 - 1.6e-08 34.6 0.1 0.0099 16.0 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO30563.1 - 2.6e-07 30.9 0.0 0.018 15.4 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 KDO30563.1 - 4.8e-05 23.1 0.9 0.58 9.9 0.0 3.6 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 KDO30563.1 - 0.00014 22.1 0.1 1.1 9.4 0.0 2.9 3 0 0 3 3 3 2 ERp29, N-terminal domain HyaE PF07449.11 KDO30563.1 - 0.0046 16.9 1.3 3.3 7.7 0.0 3.9 2 1 2 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KDO30563.1 - 0.0064 16.3 0.0 3.2 7.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin IspA PF04279.15 KDO30565.1 - 0.018 15.2 4.9 0.04 14.1 4.9 1.7 1 1 0 1 1 1 0 Intracellular septation protein A RHD3 PF05879.12 KDO30565.1 - 0.33 9.1 0.1 0.4 8.8 0.1 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) EamA PF00892.20 KDO30566.1 - 4.4 7.5 10.6 2.5 8.3 0.3 2.8 2 1 1 3 3 3 0 EamA-like transporter family IspA PF04279.15 KDO30567.1 - 0.001 19.3 5.1 0.0086 16.3 5.1 1.9 1 1 0 1 1 1 1 Intracellular septation protein A EamA PF00892.20 KDO30567.1 - 0.018 15.2 0.1 0.018 15.2 0.1 2.5 3 1 0 3 3 3 0 EamA-like transporter family DUF2499 PF10693.9 KDO30567.1 - 0.043 14.1 3.9 0.062 13.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) GPI2 PF06432.11 KDO30567.1 - 0.18 11.2 6.3 0.13 11.7 4.8 1.5 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF89 PF01937.19 KDO30568.1 - 7.5e-66 222.5 0.0 9.1e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 HATPase_c PF02518.26 KDO30569.1 - 8.8e-10 39.1 0.0 1.6e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KDO30569.1 - 8e-09 35.4 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 KDO30570.1 - 1.1e-48 165.9 0.0 1.4e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30570.1 - 2.3e-29 102.5 0.0 3.1e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO30570.1 - 0.0018 17.3 0.0 0.0038 16.2 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KDO30570.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO30570.1 - 0.023 14.3 1.0 0.037 13.6 0.0 1.8 2 1 1 3 3 3 0 RIO1 family Pkinase_fungal PF17667.1 KDO30570.1 - 0.032 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EST1_DNA_bind PF10373.9 KDO30571.1 - 3.1e-35 122.0 0.0 6.4e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KDO30571.1 - 8.7e-15 55.6 1.0 8.4e-07 29.7 0.1 2.7 2 1 1 3 3 3 2 Telomerase activating protein Est1 TPR_12 PF13424.6 KDO30571.1 - 0.067 13.5 0.4 6.3 7.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO30571.1 - 0.091 13.3 0.7 4.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30571.1 - 0.15 12.0 0.5 0.71 9.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30571.1 - 0.71 10.1 2.6 0.85 9.9 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RanBP PF00641.18 KDO30572.1 - 7.9e-14 50.7 16.3 2.6e-07 29.8 1.3 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-RING_5 PF14634.6 KDO30572.1 - 0.1 12.6 3.6 0.34 10.9 3.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 KDO30572.1 - 0.19 11.4 2.0 0.2 11.4 0.2 1.8 2 0 0 2 2 2 0 P-11 zinc finger LRAT PF04970.13 KDO30573.1 - 0.0015 18.8 0.4 0.01 16.1 0.4 2.2 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NOA36 PF06524.12 KDO30573.1 - 2.2 7.5 15.1 4.2 6.6 15.1 1.4 1 0 0 1 1 1 0 NOA36 protein ArfGap PF01412.18 KDO30576.1 - 1.3e-34 118.8 0.0 2.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 KDO30576.1 - 1.2e-17 64.1 0.0 4e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain ATG_C PF09333.11 KDO30576.1 - 9e-05 22.7 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Nucleoporin_N PF08801.11 KDO30577.1 - 4.9e-28 98.0 0.0 8.5e-27 94.0 0.0 2.2 1 1 0 1 1 1 1 Nup133 N terminal like NTP_transf_2 PF01909.23 KDO30578.1 - 4.2e-09 36.6 0.0 8.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KDO30578.1 - 0.00061 19.9 0.2 0.0025 18.0 0.2 2.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KDO30578.1 - 0.0026 17.8 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PCO_ADO PF07847.12 KDO30579.1 - 1.5e-41 142.1 0.0 5.5e-41 140.2 0.0 1.7 1 1 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 KDO30579.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Tubulin PF00091.25 KDO30580.1 - 5.5e-66 222.5 0.0 7.5e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO30580.1 - 7.7e-49 165.1 0.0 1.2e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KDO30580.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KDO30581.1 - 2.6e-66 223.6 0.0 3.7e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KDO30581.1 - 3e-50 169.6 0.1 4.8e-50 168.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KDO30581.1 - 0.0027 17.4 0.0 0.0069 16.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain DnaJ PF00226.31 KDO30582.1 - 8.2e-19 67.5 0.0 1.5e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Thiolase_N PF00108.23 KDO30583.1 - 1.6e-76 257.2 8.4 2.4e-76 256.6 8.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KDO30583.1 - 7.4e-52 174.2 0.3 1.7e-51 173.0 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KDO30583.1 - 0.00067 19.8 0.1 0.0028 17.8 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KDO30583.1 - 0.005 16.7 0.6 0.75 9.7 0.1 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Robl_LC7 PF03259.17 KDO30583.1 - 0.054 13.3 1.9 0.24 11.2 0.3 2.7 3 0 0 3 3 3 0 Roadblock/LC7 domain Rib_5-P_isom_A PF06026.14 KDO30584.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ctr PF04145.15 KDO30585.1 - 4.3e-13 50.1 16.4 6.8e-10 39.8 16.4 2.5 1 1 0 1 1 1 1 Ctr copper transporter family HMA PF00403.26 KDO30585.1 - 0.00026 21.4 0.0 0.00057 20.3 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1676 PF07898.13 KDO30585.1 - 0.17 11.9 1.3 0.34 11.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Ctr PF04145.15 KDO30586.1 - 4.4e-20 72.8 0.8 8.4e-20 71.9 0.8 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Zn_Tnp_IS1595 PF12760.7 KDO30586.1 - 0.16 12.0 0.5 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Xpo1 PF08389.12 KDO30587.1 - 7.7e-19 68.2 0.6 2.9e-18 66.3 0.6 2.1 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 KDO30587.1 - 4.1e-09 36.2 0.1 3.7e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain COX6B PF02297.17 KDO30588.1 - 1.7e-13 50.6 7.1 1.9e-13 50.4 7.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Urocanase_C PF17392.2 KDO30589.1 - 6.6e-28 97.5 3.8 7.9e-28 97.2 3.8 1.1 1 0 0 1 1 1 1 Urocanase C-terminal domain DUF2761 PF10959.8 KDO30589.1 - 0.0086 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2761) Urocanase_C PF17392.2 KDO30590.1 - 5.2e-83 277.3 2.6 1.1e-82 276.3 2.6 1.5 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 KDO30590.1 - 5.3e-69 232.1 1.2 2.3e-66 223.5 1.2 2.5 1 1 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 KDO30590.1 - 6.2e-54 181.1 3.6 1e-53 180.3 0.5 2.6 3 0 0 3 3 3 1 Urocanase N-terminal domain DUF2761 PF10959.8 KDO30590.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Methyltransf_11 PF08241.12 KDO30592.1 - 2.6e-13 50.4 0.0 3.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO30592.1 - 9.9e-11 42.2 0.1 1.5e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO30592.1 - 1.5e-08 35.3 0.0 2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO30592.1 - 4.2e-07 29.9 0.0 7.5e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KDO30592.1 - 1.4e-05 23.9 0.0 1.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 KDO30592.1 - 0.015 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KDO30592.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain SEP PF08059.13 KDO30593.1 - 6e-26 90.8 0.1 1e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KDO30593.1 - 2.7e-11 43.5 0.0 4.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain Acetyltransf_1 PF00583.25 KDO30594.1 - 5e-10 39.6 0.0 7.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO30594.1 - 1.7e-08 34.5 0.0 2.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO30594.1 - 1.8e-07 31.5 0.0 2.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO30594.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KDO30594.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PA26 PF04636.13 KDO30595.1 - 1.7e-126 422.7 0.0 2e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) RabGAP-TBC PF00566.18 KDO30596.1 - 2.5e-39 135.1 0.1 7.4e-39 133.6 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FYVE PF01363.21 KDO30596.1 - 5.7e-15 55.2 9.2 1.2e-14 54.2 9.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger Ski_Sno PF02437.17 KDO30596.1 - 0.048 13.4 0.3 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 SKI/SNO/DAC family ACBP PF00887.19 KDO30596.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Acyl CoA binding protein DUF2951 PF11166.8 KDO30597.1 - 3.6 7.9 5.2 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Nramp PF01566.18 KDO30601.1 - 8.8e-98 327.6 30.5 3.7e-50 170.9 9.5 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Apolipoprotein PF01442.18 KDO30602.1 - 0.00017 21.5 1.9 0.00017 21.5 1.9 4.3 3 1 1 4 4 4 3 Apolipoprotein A1/A4/E domain CdvA PF18822.1 KDO30602.1 - 0.08 12.8 9.0 0.43 10.4 0.4 3.9 3 1 1 4 4 4 0 CdvA-like coiled-coil domain GvpO PF05800.11 KDO30602.1 - 0.59 10.1 3.6 0.64 10.0 0.1 2.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO PA28_beta PF02252.18 KDO30602.1 - 1 9.0 6.1 0.39 10.4 0.2 3.2 3 1 0 4 4 4 0 Proteasome activator pa28 beta subunit PTR PF12789.7 KDO30602.1 - 1.2 9.3 7.3 13 6.0 0.1 3.6 4 0 0 4 4 4 0 Phage tail repeat like FliD_C PF07195.12 KDO30602.1 - 1.4 8.3 5.0 2.2 7.6 0.2 3.3 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus DUF4758 PF15950.5 KDO30602.1 - 1.7 9.0 5.1 3.2 8.1 2.3 2.7 2 1 0 2 2 2 0 Putative sperm flagellar membrane protein YtxH PF12732.7 KDO30602.1 - 5.8 7.5 8.9 2.1 8.9 0.9 3.6 2 2 0 2 2 2 0 YtxH-like protein DUF1917 PF08939.10 KDO30602.1 - 6.5 6.6 13.4 0.87 9.4 0.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1917) DUF455 PF04305.14 KDO30603.1 - 1.5e-80 270.4 0.1 1.7e-80 270.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) WD40 PF00400.32 KDO30604.1 - 2.3e-06 28.2 5.2 2.1 9.4 0.1 7.5 8 0 0 8 8 8 2 WD domain, G-beta repeat EF-hand_1 PF00036.32 KDO30604.1 - 0.0009 18.6 0.6 0.0035 16.8 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KDO30604.1 - 0.0011 18.4 0.1 0.0026 17.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO30604.1 - 0.0025 18.2 0.2 0.006 17.0 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO30604.1 - 0.0034 17.2 0.0 0.019 14.8 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain ANAPC4_WD40 PF12894.7 KDO30604.1 - 0.031 14.6 0.1 0.26 11.6 0.0 2.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 KDO30604.1 - 0.075 12.9 0.2 0.32 10.9 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair DUF3228 PF11539.8 KDO30605.1 - 5.1e-84 280.6 0.0 5.7e-84 280.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) DNA_photolyase PF00875.18 KDO30606.1 - 4e-05 23.7 0.8 7.9e-05 22.7 0.8 1.5 1 0 0 1 1 1 1 DNA photolyase IQ PF00612.27 KDO30608.1 - 1.4e-08 33.8 26.7 0.00046 19.7 0.4 5.6 5 1 1 6 6 6 4 IQ calmodulin-binding motif DUF1431 PF07248.12 KDO30608.1 - 5.1 7.4 8.2 0.5 10.6 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) Pkinase_Tyr PF07714.17 KDO30609.1 - 8.5e-40 136.7 0.0 1.8e-24 86.4 0.0 3.5 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO30609.1 - 4.6e-37 127.8 0.0 1.4e-35 123.0 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain DUF3112 PF11309.8 KDO30609.1 - 0.0055 16.2 3.5 0.013 14.9 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) Clathrin PF00637.20 KDO30610.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS Autophagy_act_C PF03987.15 KDO30611.1 - 5e-14 52.6 1.1 7.8e-14 52.0 0.6 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain zf-RING_2 PF13639.6 KDO30612.1 - 2.7e-13 50.0 6.4 2.7e-13 50.0 6.4 3.3 4 0 0 4 4 4 1 Ring finger domain FYVE PF01363.21 KDO30612.1 - 5.4e-13 48.9 19.7 5.4e-13 48.9 19.7 2.5 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KDO30612.1 - 1.2e-10 41.1 6.5 1.2e-10 41.1 6.5 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO30612.1 - 2.3e-09 36.8 2.5 2.3e-09 36.8 2.5 2.8 4 0 0 4 4 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 KDO30612.1 - 7.8e-09 35.3 5.2 7.8e-09 35.3 5.2 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30612.1 - 6.4e-08 32.8 10.2 6.4e-08 32.8 10.2 4.2 2 2 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO30612.1 - 1.3e-07 31.5 3.4 1.3e-07 31.5 3.4 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO30612.1 - 2.5e-06 27.4 5.5 2.5e-06 27.4 5.5 3.2 2 2 1 3 3 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO30612.1 - 0.00015 21.8 5.3 0.00015 21.8 5.3 3.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KDO30612.1 - 0.02 14.7 2.2 0.056 13.3 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KDO30612.1 - 0.032 14.4 4.2 0.032 14.4 4.2 3.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Pkinase_Tyr PF07714.17 KDO30613.1 - 5.5e-17 61.9 0.0 7.9e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30613.1 - 1.5e-13 50.8 0.0 2.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Amnionless PF14828.6 KDO30613.1 - 0.046 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless Pkinase_Tyr PF07714.17 KDO30616.1 - 1.4e-21 77.0 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30616.1 - 3.4e-20 72.5 0.0 5.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CcmD PF04995.14 KDO30616.1 - 0.00034 20.6 1.7 0.001 19.1 1.7 1.8 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Gram_pos_anchor PF00746.21 KDO30616.1 - 0.066 13.2 0.2 0.22 11.5 0.2 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Pkinase_Tyr PF07714.17 KDO30617.1 - 8.2e-18 64.6 0.0 1.8e-17 63.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30617.1 - 4.1e-12 46.0 0.0 1.4e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain CD34_antigen PF06365.12 KDO30617.1 - 0.0014 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Peptidase_M56 PF05569.11 KDO30617.1 - 0.0046 16.2 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 LapA_dom PF06305.11 KDO30617.1 - 0.14 12.0 2.7 0.44 10.4 2.7 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase_Tyr PF07714.17 KDO30618.1 - 6.3e-19 68.3 0.0 1.3e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30618.1 - 1.5e-16 60.5 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KDO30618.1 - 0.0011 18.6 0.2 0.099 12.4 0.1 3.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 KDO30618.1 - 0.017 15.5 0.1 6.7 7.3 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ABC_sub_bind PF04392.12 KDO30618.1 - 0.081 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein SMN PF06003.12 KDO30619.1 - 0.52 9.5 28.7 0.026 13.8 9.2 3.4 1 1 2 3 3 3 0 Survival motor neuron protein (SMN) RNase_H2_suC PF08615.11 KDO30620.1 - 7.5e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TPR_2 PF07719.17 KDO30621.1 - 0.00091 19.2 0.1 0.53 10.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30621.1 - 0.0015 18.2 0.1 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 KDO30622.1 - 0.031 14.5 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ins134_P3_kin PF05770.11 KDO30623.1 - 7.4e-32 110.5 0.0 1.2e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain TTL PF03133.15 KDO30623.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Ins134_P3_kin_N PF17927.1 KDO30623.1 - 0.12 12.8 0.1 0.4 11.1 0.0 1.9 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Pro_isomerase PF00160.21 KDO30624.1 - 9.4e-50 169.0 0.2 1e-49 168.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFS_1 PF07690.16 KDO30625.1 - 5.8e-53 180.1 39.2 1e-51 175.9 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Thi4 PF01946.17 KDO30626.1 - 2.9e-105 350.7 1.2 4.1e-105 350.2 1.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KDO30626.1 - 4.1e-08 32.7 2.2 1.6e-05 24.2 0.6 2.1 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KDO30626.1 - 1.5e-07 31.3 2.6 3.3e-06 26.9 0.8 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO30626.1 - 1.2e-06 28.6 0.1 3.6e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KDO30626.1 - 5.1e-05 22.8 0.1 8.5e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO30626.1 - 0.00065 19.0 0.1 0.00089 18.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO30626.1 - 0.0024 16.6 0.4 0.004 15.9 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KDO30626.1 - 0.0047 16.2 0.0 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KDO30626.1 - 0.01 14.9 2.1 0.4 9.7 0.8 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KDO30626.1 - 0.01 15.2 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.12 KDO30626.1 - 0.027 13.5 0.2 0.043 12.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KDO30626.1 - 0.044 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO30626.1 - 0.052 13.5 0.3 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KDO30626.1 - 0.061 12.2 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 2-oxoacid_dh PF00198.23 KDO30627.1 - 3.7e-65 219.6 0.7 3.7e-65 219.6 0.7 2.1 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KDO30627.1 - 1e-16 60.5 1.2 2.7e-16 59.2 1.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KDO30627.1 - 0.011 15.6 0.1 0.035 13.9 0.1 2.0 1 1 0 1 1 1 0 Biotin-lipoyl like GCV_H PF01597.19 KDO30627.1 - 0.016 15.1 0.5 0.048 13.5 0.5 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF4813 PF16072.5 KDO30627.1 - 0.25 10.9 19.7 0.55 9.8 19.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) MMR_HSR1 PF01926.23 KDO30629.1 - 1.6e-12 47.5 0.0 7.6e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO30629.1 - 5.9e-05 22.7 0.0 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO30629.1 - 0.0015 18.5 0.2 0.14 12.1 0.2 2.3 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KDO30629.1 - 0.015 15.4 0.1 0.015 15.4 0.1 2.2 4 0 0 4 4 4 0 Dynamin family Septin PF00735.18 KDO30629.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Septin Auto_anti-p27 PF06677.12 KDO30630.1 - 1.1e-30 105.5 15.2 3.6e-16 59.0 5.5 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRPl_C4 PF17026.5 KDO30630.1 - 0.0013 18.8 2.9 0.51 10.5 0.2 2.2 2 0 0 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type CxC6 PF18721.1 KDO30630.1 - 0.0025 18.0 0.7 1 9.7 0.1 2.4 2 0 0 2 2 2 2 CxC6 like cysteine cluster associated with KDZ transposases zf-C2H2_jaz PF12171.8 KDO30630.1 - 0.0032 17.7 3.2 0.18 12.1 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LITAF-like PF10601.9 KDO30630.1 - 0.05 13.9 8.0 1.4 9.2 0.1 2.5 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain IBR PF01485.21 KDO30630.1 - 0.068 13.4 6.1 0.96 9.7 0.2 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Rsm1 PF08600.10 KDO30630.1 - 0.11 12.6 1.0 0.32 11.2 1.0 1.7 1 0 0 1 1 1 0 Rsm1-like Gar1 PF04410.14 KDO30630.1 - 1 9.1 2.8 0.68 9.7 1.1 1.5 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region DZR PF12773.7 KDO30630.1 - 3.4 7.8 6.5 9.7 6.3 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RRN7 PF11781.8 KDO30630.1 - 5.5 6.8 7.8 1.3 8.8 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CLIP1_ZNF PF16641.5 KDO30630.1 - 5.6 7.0 7.3 2.9 7.9 1.1 2.3 2 0 0 2 2 2 0 CLIP1 zinc knuckle HSP70 PF00012.20 KDO30632.1 - 3.2e-265 881.0 4.9 3.7e-265 880.8 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO30632.1 - 2.7e-15 56.0 0.0 3.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KDO30632.1 - 0.0017 18.1 0.0 0.0053 16.5 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KDO30632.1 - 0.017 14.1 0.2 0.11 11.5 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PixA PF12306.8 KDO30632.1 - 0.08 13.1 1.7 0.11 12.7 0.4 2.0 2 0 0 2 2 2 0 Inclusion body protein Hydantoinase_A PF01968.18 KDO30632.1 - 0.1 11.8 0.1 0.28 10.4 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase MutS_III PF05192.18 KDO30632.1 - 0.2 11.8 1.8 12 6.0 1.3 2.4 2 0 0 2 2 2 0 MutS domain III PTPS PF01242.19 KDO30633.1 - 1.1e-16 61.0 0.1 1.4e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase FYVE PF01363.21 KDO30634.1 - 0.001 19.2 16.0 0.0014 18.8 16.0 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO30634.1 - 0.25 11.6 13.2 0.53 10.5 13.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger MatE PF01554.18 KDO30635.1 - 3.5e-47 160.0 35.9 2.4e-25 89.0 12.3 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KDO30635.1 - 0.0037 17.3 4.2 0.0037 17.3 4.2 4.3 2 2 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain tRNA-synt_2 PF00152.20 KDO30636.1 - 1.6e-83 280.4 0.0 2e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KDO30636.1 - 3.8e-11 42.8 0.2 7.1e-11 42.0 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KDO30636.1 - 0.002 18.3 0.0 0.013 15.6 0.0 2.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KDO30636.1 - 0.014 14.9 0.0 0.059 12.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) HSF_DNA-bind PF00447.17 KDO30637.1 - 5.5e-25 87.8 1.4 8.5e-25 87.2 1.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding THOC7 PF05615.13 KDO30637.1 - 0.041 14.2 0.3 0.065 13.5 0.3 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 GOLGA2L5 PF15070.6 KDO30637.1 - 0.091 11.4 3.5 0.12 11.0 3.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 L51_S25_CI-B8 PF05047.16 KDO30638.1 - 0.001 18.9 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SUI1 PF01253.22 KDO30639.1 - 3.1e-23 82.1 0.8 3.8e-23 81.8 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2997 PF11211.8 KDO30639.1 - 0.026 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Neuropeptide_S PF14993.6 KDO30640.1 - 0.033 14.0 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein CENP-B_dimeris PF09026.10 KDO30640.1 - 0.32 11.4 9.1 0.32 11.4 6.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SKN1 PF03935.15 KDO30643.1 - 2.2e-42 145.1 12.3 2.8e-25 88.7 1.1 3.4 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) LRR_4 PF12799.7 KDO30645.1 - 0.0027 18.1 0.4 0.72 10.4 0.0 3.3 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO30645.1 - 0.19 11.9 0.3 40 4.6 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeat DUF4774 PF15999.5 KDO30646.1 - 0.69 9.8 3.1 16 5.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4774) TPT PF03151.16 KDO30647.1 - 0.0018 17.7 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TPT PF03151.16 KDO30648.1 - 2.7e-26 92.6 9.5 3.2e-26 92.3 9.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KDO30648.1 - 0.0017 18.5 13.4 0.0062 16.7 3.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Bromo_coat PF01318.18 KDO30648.1 - 0.024 14.7 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Bromovirus coat protein TNFR_16_TM PF18422.1 KDO30648.1 - 3.6 7.6 5.6 1.7 8.6 1.5 2.4 1 1 1 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Dus PF01207.17 KDO30649.1 - 3.7e-19 69.0 0.0 4.9e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2_jaz PF12171.8 KDO30649.1 - 0.00046 20.4 0.1 0.001 19.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KDO30649.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 U1 zinc finger NMO PF03060.15 KDO30649.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase zf-met PF12874.7 KDO30649.1 - 0.086 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SpoIISA_toxin PF14171.6 KDO30649.1 - 0.13 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system PROCT PF08084.11 KDO30655.1 - 1.4e-52 176.8 0.1 2.1e-52 176.2 0.1 1.3 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KDO30655.1 - 1.5e-08 34.7 0.0 3.6e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Solute_trans_a PF03619.16 KDO30656.1 - 6.5e-71 239.0 14.5 8e-71 238.7 14.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4231 PF14015.6 KDO30656.1 - 1 9.8 4.7 3.9 8.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Glyco_hydro_18 PF00704.28 KDO30658.1 - 1.5e-55 189.1 0.1 1.8e-55 188.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ribosomal_S16 PF00886.19 KDO30660.1 - 2.1e-25 88.6 0.1 2.7e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 PARP PF00644.20 KDO30661.1 - 2.5e-47 161.0 0.0 3.9e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KDO30661.1 - 2.8e-09 37.2 0.0 8.4e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain PRORP PF16953.5 KDO30662.1 - 5.1e-14 52.4 0.6 8.4e-11 41.8 0.1 2.7 2 1 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 KDO30662.1 - 2.1e-10 40.4 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Condensation PF00668.20 KDO30662.1 - 0.058 12.0 0.2 0.098 11.3 0.2 1.3 1 0 0 1 1 1 0 Condensation domain PPR PF01535.20 KDO30662.1 - 0.12 12.6 0.0 13 6.3 0.0 2.5 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 KDO30662.1 - 0.17 12.1 0.0 0.48 10.7 0.0 1.8 2 0 0 2 2 2 0 PPR repeat family GIY-YIG PF01541.24 KDO30663.1 - 1.7e-11 44.2 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KDO30663.1 - 0.0026 17.9 5.0 0.0049 17.0 5.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KDO30663.1 - 0.0092 16.2 1.5 0.024 14.9 1.4 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-RING_11 PF17123.5 KDO30663.1 - 0.036 13.8 2.2 0.11 12.3 2.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-HC5HC2H_2 PF13832.6 KDO30663.1 - 0.14 12.4 2.6 0.3 11.3 2.6 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KDO30663.1 - 0.14 12.5 5.7 0.3 11.4 5.7 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KDO30663.1 - 5.1 7.1 7.0 9.8 6.2 7.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2946 PF11162.8 KDO30663.1 - 5.3 7.7 12.9 0.96 10.1 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) PHD PF00628.29 KDO30663.1 - 7.9 6.5 10.5 17 5.4 10.4 1.7 1 1 0 1 1 1 0 PHD-finger Pkinase PF00069.25 KDO30665.1 - 1.4e-55 188.5 0.0 1.8e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30665.1 - 2.4e-23 82.8 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KDO30665.1 - 1.9e-15 57.1 0.4 4e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO30665.1 - 2.9e-15 54.6 4.2 7.1e-05 22.1 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KDO30665.1 - 1.2e-13 50.6 1.7 1.5e-05 24.7 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO30665.1 - 3e-12 45.4 2.6 0.0032 17.3 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KDO30665.1 - 1.1e-10 40.4 5.3 0.0072 15.8 0.3 3.4 3 0 0 3 3 3 3 EF hand Kinase-like PF14531.6 KDO30665.1 - 0.0016 17.8 0.0 0.18 11.1 0.0 2.5 2 1 0 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.9 KDO30665.1 - 0.019 15.3 1.4 1.7 9.0 0.1 2.7 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO30665.1 - 0.073 13.4 0.2 0.7 10.3 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 KDO30665.1 - 0.17 11.9 3.3 1.2 9.2 0.2 3.4 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Iso_dh PF00180.20 KDO30666.1 - 5.5e-77 259.2 0.0 6.4e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HECT PF00632.25 KDO30667.1 - 8.8e-67 225.7 0.0 1.6e-66 224.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase_Tyr PF07714.17 KDO30668.1 - 1.1e-15 57.6 0.0 3.9e-08 32.9 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO30668.1 - 1e-13 51.3 0.0 4.8e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain zf-RING_2 PF13639.6 KDO30668.1 - 1.6e-05 25.1 11.4 1.6e-05 25.1 11.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO30668.1 - 3.2e-05 23.7 12.2 8.4e-05 22.3 12.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 KDO30668.1 - 0.00083 19.7 0.1 0.0019 18.5 0.1 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO30668.1 - 0.093 12.5 0.1 0.24 11.2 0.1 1.8 2 0 0 2 2 2 0 Leucine rich repeat LRR_9 PF14580.6 KDO30668.1 - 0.12 11.8 0.2 0.37 10.3 0.1 1.8 1 1 0 1 1 1 0 Leucine-rich repeat zf-RING_UBOX PF13445.6 KDO30668.1 - 0.9 9.6 10.2 2.1 8.4 10.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KDO30668.1 - 2.5 8.1 14.8 7.7 6.6 15.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 KDO30668.1 - 3.5 7.6 9.1 8.3 6.4 9.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ALO PF04030.14 KDO30670.1 - 1.9e-22 80.4 0.1 7.8e-22 78.3 0.1 1.8 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KDO30670.1 - 3.8e-22 78.5 0.2 5.8e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain His_Phos_1 PF00300.22 KDO30671.1 - 2.9e-34 118.5 0.0 6.6e-27 94.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 KDO30671.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain LRR_4 PF12799.7 KDO30672.1 - 0.3 11.5 1.8 13 6.3 0.0 3.4 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KDO30673.1 - 1.7e-80 270.2 0.0 4.3e-80 268.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30673.1 - 9.1e-43 146.4 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KDO30673.1 - 1.2e-12 48.3 0.4 3.7e-12 46.7 0.3 1.8 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase KA1 PF02149.19 KDO30673.1 - 1.3e-08 34.5 0.2 3.5e-08 33.1 0.2 1.8 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KDO30673.1 - 3.2e-08 33.2 0.0 8.8e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO30673.1 - 0.00096 18.8 0.2 0.0018 17.9 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO30673.1 - 0.0094 15.9 0.3 0.022 14.7 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO30673.1 - 0.015 14.3 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Glycos_trans_3N PF02885.17 KDO30673.1 - 0.04 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain AAA_5 PF07728.14 KDO30673.1 - 0.21 11.6 0.2 1 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) JmjC PF02373.22 KDO30675.1 - 2.6e-40 137.4 0.0 3.7e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KDO30675.1 - 1.8e-09 37.4 0.5 1.8e-09 37.4 0.5 1.8 2 0 0 2 2 2 1 jmjN domain Med12-LCEWAV PF12145.8 KDO30676.1 - 0.015 14.2 0.7 0.078 11.8 0.7 2.0 1 1 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain NapD PF03927.13 KDO30677.1 - 0.057 13.5 0.3 0.057 13.5 0.3 2.3 2 0 0 2 2 2 0 NapD protein GPI2 PF06432.11 KDO30678.1 - 1.7e-79 267.2 15.5 2e-79 267.0 15.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Dymeclin PF09742.9 KDO30678.1 - 0.18 10.2 2.3 0.3 9.5 2.3 1.3 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein DUF872 PF05915.12 KDO30678.1 - 1.3 9.2 4.0 7 6.9 1.8 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Myb_DNA-binding PF00249.31 KDO30679.1 - 5.5e-09 36.1 0.1 8.4e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO30679.1 - 0.17 12.2 0.2 0.32 11.3 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain tRNA_int_end_N2 PF12928.7 KDO30680.1 - 4e-06 26.9 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KDO30680.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain COX2-transmemb PF09125.10 KDO30682.1 - 0.018 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane SPAR_C PF11881.8 KDO30682.1 - 0.11 12.4 0.3 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 C-terminal domain of SPAR protein Peptidase_S51 PF03575.17 KDO30683.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 zf-BED PF02892.15 KDO30683.1 - 0.0072 16.3 0.8 0.015 15.4 0.8 1.6 1 0 0 1 1 1 1 BED zinc finger GATase_3 PF07685.14 KDO30683.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain RNase_PH PF01138.21 KDO30684.1 - 1.7e-26 93.3 0.1 2.9e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO30684.1 - 9.6e-06 25.5 0.1 1.9e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 WD40 PF00400.32 KDO30685.1 - 6.2e-46 153.4 16.4 1.6e-09 38.2 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30685.1 - 3.2e-20 72.2 1.3 0.00028 21.1 0.0 5.5 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KDO30685.1 - 9.5e-14 50.7 1.0 9.5e-14 50.7 1.0 2.6 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 KDO30685.1 - 6.7e-07 28.6 0.1 0.0028 16.7 0.0 3.8 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO30685.1 - 2.7e-05 24.1 0.0 0.067 13.1 0.0 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KDO30685.1 - 0.019 14.3 0.2 35 3.6 0.0 3.8 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Marek_SORF3 PF07153.11 KDO30685.1 - 0.072 12.4 0.1 1.1 8.5 0.1 2.6 1 1 2 3 3 3 0 Marek's disease-like virus SORF3 protein WD40_like PF17005.5 KDO30685.1 - 0.2 10.9 0.0 4.3 6.6 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain MCD PF05292.11 KDO30686.1 - 2.2e-62 210.9 0.0 3.1e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain cNMP_binding PF00027.29 KDO30686.1 - 6.5e-07 29.3 0.0 1.8e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_4 PF12799.7 KDO30687.1 - 3.2e-29 100.5 14.2 3.1e-06 27.4 1.0 6.9 5 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO30687.1 - 2.3e-19 68.9 24.2 4.8e-08 32.6 3.8 5.5 2 1 6 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 KDO30687.1 - 2.3e-12 46.8 6.6 4e-06 26.4 0.1 3.5 1 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KDO30687.1 - 8.1e-11 41.1 7.0 0.11 12.6 0.0 8.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 KDO30687.1 - 0.00023 21.2 19.4 28 5.8 0.0 9.1 9 1 1 10 10 10 1 Leucine Rich Repeat Mito_carr PF00153.27 KDO30689.1 - 2.8e-58 193.9 6.0 8.3e-20 70.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_2 PF07719.17 KDO30690.1 - 6.1e-54 175.8 43.8 0.00013 21.8 0.2 22.8 22 1 1 23 23 23 14 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30690.1 - 2.7e-45 150.4 36.7 1.1e-06 28.2 0.2 22.3 24 0 0 24 24 23 9 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30690.1 - 2.1e-44 148.9 27.2 0.0021 17.7 0.0 16.8 14 2 3 17 17 17 14 TPR repeat TPR_9 PF13371.6 KDO30690.1 - 1.7e-34 117.8 68.7 5.5e-08 32.8 1.9 15.8 7 5 9 16 16 16 10 Tetratricopeptide repeat TPR_16 PF13432.6 KDO30690.1 - 1.7e-32 111.7 91.1 5e-07 30.3 2.9 16.0 14 2 5 19 19 18 9 Tetratricopeptide repeat TPR_17 PF13431.6 KDO30690.1 - 2.4e-30 102.7 29.3 0.033 14.6 0.0 20.1 22 0 0 22 22 20 7 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30690.1 - 2.7e-29 98.9 19.6 0.015 15.5 0.0 17.2 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30690.1 - 8.8e-28 94.6 67.0 0.0019 18.8 0.2 18.7 10 6 13 23 23 21 8 Tetratricopeptide repeat TPR_19 PF14559.6 KDO30690.1 - 3.4e-27 94.7 36.1 2.8e-05 24.5 0.0 13.1 8 6 5 14 14 14 5 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30690.1 - 2.6e-11 42.7 41.2 0.21 11.7 0.0 14.6 16 1 0 16 16 16 4 Tetratricopeptide repeat TPR_6 PF13174.6 KDO30690.1 - 4.3e-09 36.4 57.0 0.011 16.3 0.3 16.5 21 0 0 21 21 17 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO30690.1 - 3.8e-08 33.4 28.3 0.02 15.1 0.8 8.2 7 1 1 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KDO30690.1 - 4.3e-08 32.5 7.0 0.00015 20.9 0.0 5.4 5 1 1 6 6 6 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 KDO30690.1 - 3.9e-07 30.3 61.4 0.018 15.3 0.0 14.0 10 4 5 16 16 16 4 Tetratricopeptide repeat TPR_20 PF14561.6 KDO30690.1 - 0.00013 22.2 31.8 0.7 10.3 0.1 9.8 9 3 2 11 11 10 2 Tetratricopeptide repeat BTAD PF03704.17 KDO30690.1 - 0.00031 21.2 35.0 0.23 11.9 0.1 9.1 6 3 3 9 9 9 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 KDO30690.1 - 0.012 15.6 3.0 13 5.9 0.0 5.6 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 KDO30690.1 - 0.016 14.2 0.1 0.038 13.0 0.1 1.6 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_15 PF13429.6 KDO30690.1 - 0.026 13.7 26.9 0.48 9.6 0.1 8.1 6 3 2 9 9 9 0 Tetratricopeptide repeat ChAPs PF09295.10 KDO30690.1 - 0.23 10.4 0.3 17 4.3 0.0 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PI3_PI4_kinase PF00454.27 KDO30692.1 - 7.2e-35 121.0 0.0 3.3e-23 82.8 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 KDO30692.1 - 5.7e-14 52.5 0.1 1.3e-13 51.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KDO30692.1 - 0.00053 20.3 0.2 0.0039 17.6 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain DUF4135 PF13575.6 KDO30692.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CCDC24 PF15669.5 KDO30692.1 - 0.025 14.4 1.3 0.12 12.2 0.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family PH_11 PF15413.6 KDO30692.1 - 0.44 11.0 1.3 4.3 7.8 1.3 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Ribonuclease_T2 PF00445.18 KDO30693.1 - 4.9e-23 82.3 0.7 7e-23 81.8 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family XPG_N PF00752.17 KDO30694.1 - 6e-31 106.9 0.0 1.1e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KDO30694.1 - 4.7e-27 94.2 0.0 1.2e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KDO30694.1 - 0.00024 21.6 0.0 0.00074 20.1 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 KDO30694.1 - 0.058 12.8 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus 5_3_exonuc_N PF02739.16 KDO30694.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain zf-CCHC PF00098.23 KDO30695.1 - 1.5e-15 56.4 38.0 1.7e-06 27.9 1.7 6.2 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_6 PF15288.6 KDO30695.1 - 0.024 14.5 0.1 0.024 14.5 0.1 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 KDO30695.1 - 0.058 13.1 30.4 0.28 11.0 0.7 5.1 4 1 1 5 5 5 0 Zinc knuckle MatE PF01554.18 KDO30696.1 - 1.7e-48 164.4 28.9 1e-24 87.0 9.9 2.2 2 0 0 2 2 2 2 MatE DUF2208 PF09973.9 KDO30696.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2208) MatE PF01554.18 KDO30697.1 - 3.4e-48 163.4 41.1 2.2e-24 85.9 14.0 2.7 3 0 0 3 3 3 2 MatE Ank_4 PF13637.6 KDO30698.1 - 3.3e-21 75.4 3.6 5.5e-10 39.6 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30698.1 - 9.5e-17 61.4 0.7 7.3e-13 48.9 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO30698.1 - 1.4e-16 60.3 1.4 1e-11 44.8 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO30698.1 - 1.2e-11 44.5 1.4 2.2e-08 34.2 0.8 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO30698.1 - 2.4e-09 36.7 0.2 1.7e-06 27.9 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KDO30701.1 - 9.8e-42 141.4 20.6 5.5e-14 52.5 0.1 4.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO30701.1 - 1.4e-32 108.0 10.5 6.4e-05 23.1 0.0 8.2 8 0 0 8 8 7 7 Ankyrin repeat Ank_5 PF13857.6 KDO30701.1 - 5e-30 103.2 14.7 3.6e-08 33.5 0.5 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO30701.1 - 1.7e-29 101.8 11.0 4.5e-10 39.9 0.5 5.9 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO30701.1 - 1.1e-28 98.3 15.7 9.5e-05 22.7 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat zf-C3HC4_3 PF13920.6 KDO30701.1 - 8e-08 32.0 8.1 8e-08 32.0 8.1 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO30701.1 - 0.00012 21.8 10.1 0.00012 21.8 10.1 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO30701.1 - 0.021 14.7 10.5 0.021 14.7 10.5 2.2 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Pro_CA PF00484.19 KDO30701.1 - 0.022 15.1 1.4 0.28 11.5 0.6 2.5 2 0 0 2 2 2 0 Carbonic anhydrase DUF2039 PF10217.9 KDO30701.1 - 0.89 9.9 10.9 0.8 10.1 6.5 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.7 KDO30701.1 - 1 9.5 17.3 3.3 7.8 2.1 2.9 1 1 2 3 3 3 0 Double zinc ribbon zf-RING_UBOX PF13445.6 KDO30701.1 - 1 9.4 7.9 2.5 8.2 7.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Gin PF10764.9 KDO30701.1 - 1.2 9.2 7.9 3.4 7.7 7.9 1.9 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-C3HC4_4 PF15227.6 KDO30701.1 - 3 8.1 7.6 3.2 8.0 3.8 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KDO30701.1 - 3.9 7.4 15.1 1.2 9.1 8.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO30701.1 - 9.6 6.6 19.3 0.045 14.1 9.0 2.4 2 1 0 2 2 1 0 Ring finger domain Ank_4 PF13637.6 KDO30702.1 - 1.5e-32 111.5 6.6 1.4e-12 47.9 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30702.1 - 5.4e-29 100.6 1.7 1.3e-11 44.9 0.4 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO30702.1 - 4.4e-27 93.8 8.2 2.5e-09 37.2 0.1 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30702.1 - 3.9e-24 82.1 1.4 0.00039 20.6 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KDO30702.1 - 6.9e-24 83.2 7.8 7.7e-06 26.1 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat zf-C3HC4_3 PF13920.6 KDO30702.1 - 1.2e-05 25.0 16.2 1.2e-05 25.0 16.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO30702.1 - 2.9 7.8 24.8 0.49 10.3 18.8 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) AAA_26 PF13500.6 KDO30703.1 - 3.9e-43 147.6 0.0 5.2e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 KDO30703.1 - 3.7e-07 29.9 0.0 2.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 DRTGG domain CbiA PF01656.23 KDO30703.1 - 0.0003 20.9 0.0 0.00061 19.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Gly_reductase PF09338.11 KDO30703.1 - 0.11 10.9 0.3 0.17 10.2 0.3 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits Kinesin PF00225.23 KDO30704.1 - 5.6e-79 265.5 0.1 8.1e-79 264.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30704.1 - 2.6e-12 46.9 0.0 5.6e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KDO30704.1 - 0.055 13.8 0.2 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KDO30704.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KDO30704.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.17 KDO30707.1 - 2.5e-08 33.8 11.2 3.5e-08 33.4 11.2 1.2 1 0 0 1 1 1 1 Yip1 domain Collagen PF01391.18 KDO30707.1 - 0.0034 17.1 13.0 0.0034 17.1 13.0 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) DUF2759 PF10958.8 KDO30707.1 - 6.2 6.6 10.1 0.77 9.5 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) Ion_trans PF00520.31 KDO30708.1 - 2.8e-167 554.0 58.8 1.8e-52 178.0 5.3 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KDO30708.1 - 6.1e-11 41.6 68.4 3.8e-05 22.5 3.7 7.9 6 3 3 9 9 9 5 Polycystin cation channel EF-hand_7 PF13499.6 KDO30708.1 - 4.3e-09 36.7 0.1 3.1e-07 30.7 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO30708.1 - 5.4e-09 35.0 0.2 0.00095 18.6 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KDO30708.1 - 9.5e-08 31.2 0.3 0.00046 19.5 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO30708.1 - 1.1e-07 31.2 0.7 0.0035 17.1 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KDO30708.1 - 5e-06 26.3 0.4 0.19 11.6 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain pair DEP PF00610.21 KDO30708.1 - 0.0007 19.6 0.1 0.049 13.7 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Caleosin PF05042.13 KDO30708.1 - 0.013 15.4 0.0 0.045 13.7 0.0 1.9 1 0 0 1 1 1 0 Caleosin related protein EF-hand_9 PF14658.6 KDO30708.1 - 0.042 14.2 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain FAM176 PF14851.6 KDO30708.1 - 0.3 10.7 0.6 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Anoctamin PF04547.12 KDO30709.1 - 3.7e-107 359.0 6.2 4.4e-107 358.7 6.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DsrH PF04077.12 KDO30709.1 - 0.032 14.4 0.1 0.096 12.8 0.1 1.8 1 0 0 1 1 1 0 DsrH like protein DUF4574 PF15141.6 KDO30709.1 - 0.28 11.1 1.5 0.88 9.5 0.0 2.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CBAH PF02275.18 KDO30710.1 - 5.9e-19 68.9 0.0 1.2e-18 67.8 0.0 1.5 2 0 0 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family ALMS_motif PF15309.6 KDO30712.1 - 9.6e-07 29.3 11.4 9.6e-07 29.3 11.4 2.0 1 1 1 2 2 2 1 ALMS motif Nucleoside_tran PF01733.18 KDO30713.1 - 9e-05 22.0 0.6 9e-05 22.0 0.6 1.6 1 1 0 1 1 1 1 Nucleoside transporter DUF2304 PF10066.9 KDO30713.1 - 9.5 6.5 9.8 4.6 7.5 4.4 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Aph-1 PF06105.12 KDO30715.1 - 6.4e-47 159.9 17.0 7.6e-47 159.6 17.0 1.0 1 0 0 1 1 1 1 Aph-1 protein PhoLip_ATPase_C PF16212.5 KDO30716.1 - 2.2e-74 250.3 20.4 2.2e-74 250.3 20.4 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO30716.1 - 1.1e-18 66.7 4.1 1.1e-18 66.7 4.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KDO30716.1 - 6.6e-12 45.3 0.0 1e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO30716.1 - 2.5e-10 41.0 0.4 0.00064 20.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KDO30716.1 - 9.9e-09 35.0 0.2 3.1e-08 33.4 0.2 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO30716.1 - 0.00029 20.7 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tmemb_55A PF09788.9 KDO30716.1 - 1.3 8.1 7.7 0.092 11.8 1.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 55A PKD_channel PF08016.12 KDO30717.1 - 4.1e-61 206.9 12.6 4.5e-60 203.5 12.6 2.0 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KDO30717.1 - 2.3e-14 53.2 16.9 2.3e-14 53.2 16.9 1.8 2 1 0 2 2 2 1 Ion transport protein DUF2618 PF10940.8 KDO30718.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) PhoLip_ATPase_C PF16212.5 KDO30720.1 - 5.1e-62 209.9 22.7 5.1e-62 209.9 22.7 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO30720.1 - 2.4e-22 78.4 0.1 8.4e-22 76.7 0.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO30720.1 - 1.9e-10 41.4 1.0 0.0011 19.3 0.0 3.6 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO30720.1 - 4.8e-10 39.4 0.0 1e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO30720.1 - 7e-07 28.9 0.4 1.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO30720.1 - 8.2e-05 22.5 0.1 0.004 16.9 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 KDO30721.1 - 2.5e-33 113.6 26.5 1.4e-06 28.9 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30721.1 - 1.1e-11 44.8 0.2 0.22 11.8 0.0 5.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO30721.1 - 0.002 17.5 0.2 0.53 9.5 0.1 2.9 1 1 1 2 2 2 2 WD40-like domain UPF0020 PF01170.18 KDO30722.1 - 6.8e-23 81.4 0.0 5.7e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PPR_2 PF13041.6 KDO30722.1 - 3.9e-07 30.2 0.0 0.019 15.1 0.0 2.9 1 1 1 2 2 2 2 PPR repeat family Methyltransf_25 PF13649.6 KDO30722.1 - 8.8e-07 29.6 0.0 2.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PPR PF01535.20 KDO30722.1 - 4.4e-06 26.6 0.1 0.12 12.6 0.0 3.3 3 0 0 3 3 3 2 PPR repeat THUMP PF02926.17 KDO30722.1 - 5.8e-06 26.5 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Methyltransf_31 PF13847.6 KDO30722.1 - 9.8e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PPR_3 PF13812.6 KDO30722.1 - 2e-05 24.5 0.0 0.0051 16.9 0.0 3.2 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KDO30722.1 - 4.7e-05 23.0 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 PPR repeat Methyltransf_11 PF08241.12 KDO30722.1 - 0.00011 22.7 0.0 0.00031 21.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO30722.1 - 0.00016 21.3 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PPR_long PF17177.4 KDO30722.1 - 0.00077 18.9 0.3 0.0013 18.2 0.3 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Ubie_methyltran PF01209.18 KDO30722.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.8 KDO30722.1 - 0.024 14.1 0.0 0.16 11.4 0.0 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Rep_fac_C PF08542.11 KDO30723.1 - 4e-21 75.2 0.0 8.8e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KDO30723.1 - 5.9e-13 48.9 0.1 1.7e-10 41.0 0.6 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KDO30723.1 - 8.7e-13 48.8 0.2 1.4e-12 48.2 0.2 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KDO30723.1 - 4.1e-07 30.1 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO30723.1 - 1.8e-06 28.5 0.0 0.00011 22.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO30723.1 - 2e-05 24.4 0.1 8.2e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KDO30723.1 - 4.5e-05 23.5 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KDO30723.1 - 9.5e-05 22.7 0.2 0.063 13.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KDO30723.1 - 0.00015 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KDO30723.1 - 0.00018 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KDO30723.1 - 0.00045 19.7 0.0 0.016 14.6 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KDO30723.1 - 0.0027 18.0 0.7 0.015 15.7 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KDO30723.1 - 0.0027 17.6 0.1 0.0045 16.8 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KDO30723.1 - 0.0039 17.0 0.1 0.009 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO30723.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KDO30723.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KDO30723.1 - 0.0092 15.4 0.1 0.56 9.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein NTPase_1 PF03266.15 KDO30723.1 - 0.0093 15.9 0.7 0.094 12.6 0.1 2.2 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KDO30723.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KDO30723.1 - 0.024 14.4 0.4 0.062 13.0 0.4 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KDO30723.1 - 0.024 14.4 0.4 2.4 7.9 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 KDO30723.1 - 0.047 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_assoc_2 PF16193.5 KDO30723.1 - 0.048 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_28 PF13521.6 KDO30723.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KDO30723.1 - 0.11 11.7 0.4 1.9 7.6 0.4 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 KDO30723.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KDO30723.1 - 0.14 12.7 0.2 0.29 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KDO30724.1 - 3.6e-62 210.1 0.6 7e-62 209.2 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KDO30724.1 - 8.1e-20 70.5 1.0 6.6e-10 38.7 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KDO30724.1 - 1.6e-18 67.1 0.3 1.6e-17 63.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO30724.1 - 5.8e-12 45.9 0.0 1.4e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO30724.1 - 3e-05 23.9 0.0 8.7e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KDO30724.1 - 0.0012 18.0 0.0 0.0033 16.6 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 KDO30724.1 - 0.022 15.0 0.4 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4449 PF14613.6 KDO30724.1 - 0.041 14.0 0.1 0.041 14.0 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4449) DUF5076 PF16826.5 KDO30724.1 - 0.11 12.4 0.6 0.32 10.9 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) CHDCT2 PF08074.11 KDO30724.1 - 0.28 11.3 2.7 0.66 10.1 0.0 3.1 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain PHD PF00628.29 KDO30725.1 - 9.4e-10 38.2 5.7 1.2e-09 37.9 5.7 1.2 1 0 0 1 1 1 1 PHD-finger Cys_rich_CPCC PF14206.6 KDO30725.1 - 0.0019 17.9 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich CPCC Rtf2 PF04641.12 KDO30725.1 - 0.055 12.8 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger HIP1_clath_bdg PF16515.5 KDO30726.1 - 0.012 16.2 6.0 0.012 16.2 6.0 9.7 2 1 7 10 10 10 0 Clathrin-binding domain of Huntingtin-interacting protein 1 adh_short PF00106.25 KDO30727.1 - 1.8e-32 112.4 0.0 2.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO30727.1 - 2.4e-27 96.0 0.0 2.9e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KDO30727.1 - 0.0015 18.5 0.1 0.0047 16.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KDO30727.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 KDO30727.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KDO30727.1 - 0.019 14.5 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HTH_Tnp_IS1 PF12759.7 KDO30727.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 InsA C-terminal domain RmlD_sub_bind PF04321.17 KDO30727.1 - 0.048 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KDO30728.1 - 5.1e-16 58.7 0.1 6.6e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO30728.1 - 1.7e-13 50.7 0.1 1.9e-13 50.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UQ_con PF00179.26 KDO30731.1 - 2.9e-48 163.1 0.0 3.4e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nfu_N PF08712.11 KDO30732.1 - 5.4e-27 93.7 0.0 1.3e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KDO30732.1 - 6e-24 84.0 0.0 1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain MYEOV2 PF15004.6 KDO30733.1 - 1.7 9.1 15.5 4.8 7.7 15.5 1.7 1 1 0 1 1 1 0 Myeloma-overexpressed-like Longin PF13774.6 KDO30734.1 - 8.9e-22 76.9 0.0 1.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KDO30734.1 - 3.3e-16 58.8 0.2 6.3e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 Synaptobrevin COQ9 PF08511.11 KDO30734.1 - 0.0049 16.6 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 COQ9 Sec20 PF03908.13 KDO30734.1 - 0.73 9.8 5.6 13 5.8 3.2 3.0 2 1 0 2 2 2 0 Sec20 WD40 PF00400.32 KDO30735.1 - 2.1e-24 85.3 14.7 0.0027 18.5 0.6 9.6 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30735.1 - 1.1e-08 35.3 0.3 2.8 8.3 0.0 6.4 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain TFIID_20kDa PF03847.13 KDO30735.1 - 9.1e-05 22.9 0.0 0.00051 20.5 0.0 2.2 3 0 0 3 3 3 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 KDO30735.1 - 0.036 14.1 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PPK2 PF03976.14 KDO30736.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) DUF1793 PF08760.11 KDO30738.1 - 0.0067 16.9 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Uteroglobin PF01099.17 KDO30738.1 - 0.07 13.5 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Uteroglobin family DUF2767 PF10965.8 KDO30738.1 - 0.24 11.4 3.9 0.33 11.0 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2767) MHYT PF03707.16 KDO30738.1 - 0.45 10.7 7.2 5.7 7.2 0.9 2.7 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat zf-CCCH_4 PF18044.1 KDO30740.1 - 1.7e-09 37.2 2.2 3.3e-09 36.3 2.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO30740.1 - 2.3e-07 30.7 5.5 4.3e-07 29.8 5.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KDO30740.1 - 5.9e-07 29.2 3.4 1.3e-06 28.2 3.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KDO30740.1 - 0.0033 17.8 2.3 0.0033 17.8 2.3 2.3 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger DUF2457 PF10446.9 KDO30740.1 - 0.27 10.4 9.6 0.34 10.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_8 PF13855.6 KDO30741.1 - 5.6e-13 48.4 4.1 2.4e-09 36.8 2.3 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO30741.1 - 3.1e-12 46.5 9.9 8.4e-06 26.0 2.6 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO30741.1 - 5.5e-07 29.3 0.6 0.00058 19.4 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat KASH_CCD PF14662.6 KDO30741.1 - 0.085 12.7 4.9 0.15 11.8 4.9 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 KDO30741.1 - 1.9 9.0 8.0 67 4.0 7.1 3.2 1 1 0 1 1 1 0 Cell division protein ZapB Cnn_1N PF07989.11 KDO30741.1 - 2.3 8.4 4.9 2 8.7 0.9 2.5 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KDO30741.1 - 2.5 7.9 6.4 14 5.5 0.5 2.9 2 1 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 KDO30741.1 - 3.6 7.9 7.9 7.6 6.8 0.0 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 KDO30741.1 - 5 7.3 7.0 9 6.5 0.1 3.0 2 1 0 2 2 2 0 Basic region leucine zipper LRR_1 PF00560.33 KDO30741.1 - 6.9 7.6 9.5 81 4.4 0.0 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 KDO30742.1 - 1.2e-65 221.5 0.0 1.4e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30742.1 - 3.3e-27 95.4 0.0 4.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO30742.1 - 7.2e-05 22.2 0.5 0.0002 20.8 0.4 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO30742.1 - 0.00013 21.4 0.0 0.0012 18.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KDO30742.1 - 0.00021 21.3 2.4 0.0018 18.2 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KDO30742.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KDO30742.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain RRM_1 PF00076.22 KDO30743.1 - 1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO30743.1 - 0.0039 17.0 0.0 0.0048 16.7 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif DUF3343 PF11823.8 KDO30743.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RRM_8 PF11835.8 KDO30743.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 RRM-like domain Pkinase PF00069.25 KDO30744.1 - 2.5e-68 230.3 0.0 3.1e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30744.1 - 2.7e-31 108.8 0.0 3.8e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO30744.1 - 8.4e-06 25.3 0.0 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KDO30744.1 - 0.00034 20.0 0.2 0.00054 19.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO30744.1 - 0.002 18.1 0.4 0.056 13.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KDO30744.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SWI-SNF_Ssr4 PF08549.10 KDO30745.1 - 3.6 6.1 7.6 0.21 10.2 0.8 1.9 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Tetraspanin PF00335.20 KDO30746.1 - 3.2e-08 33.6 7.5 4.8e-08 33.0 7.5 1.4 1 1 0 1 1 1 1 Tetraspanin family TMEM174 PF15029.6 KDO30746.1 - 0.65 9.7 3.7 1.1 8.9 3.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 TPR_12 PF13424.6 KDO30747.1 - 2.3e-14 53.4 15.1 0.00016 21.9 0.5 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30747.1 - 2.1e-07 30.5 12.9 0.095 12.8 0.1 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30747.1 - 2.6e-05 23.8 18.7 0.11 12.3 0.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO30747.1 - 0.00011 21.7 4.1 0.00019 20.9 4.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 KDO30747.1 - 0.0013 18.8 14.8 0.81 10.1 0.3 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO30747.1 - 0.0052 16.8 19.7 0.39 10.9 0.3 5.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO30747.1 - 0.022 15.5 9.6 0.053 14.4 0.5 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO30747.1 - 0.45 10.5 12.3 2.4 8.1 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO30747.1 - 1 9.9 3.8 42 4.8 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat CASP_C PF08172.12 KDO30748.1 - 1.6e-34 119.4 13.9 1.6e-34 119.4 13.9 3.3 2 1 0 2 2 2 1 CASP C terminal Golgin_A5 PF09787.9 KDO30748.1 - 0.0057 16.2 1.8 0.0057 16.2 1.8 4.4 2 1 3 5 5 5 1 Golgin subfamily A member 5 Nsp1_C PF05064.13 KDO30748.1 - 0.13 12.1 0.1 0.13 12.1 0.1 4.9 5 1 1 6 6 6 0 Nsp1-like C-terminal region DUF2721 PF11026.8 KDO30748.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) DUF2461 PF09365.10 KDO30748.1 - 0.81 9.6 4.2 0.99 9.3 0.2 2.9 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) PEARLI-4 PF05278.12 KDO30748.1 - 4.5 6.8 11.5 0.45 10.1 0.3 3.4 2 1 2 4 4 4 0 Arabidopsis phospholipase-like protein (PEARLI 4) EGF_2 PF07974.13 KDO30749.1 - 2.7e-13 50.0 60.3 4.7e-06 26.9 4.3 5.4 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 KDO30749.1 - 0.00019 21.5 47.2 0.19 11.9 6.0 4.6 3 1 1 4 4 4 3 Laminin EGF domain EGF PF00008.27 KDO30749.1 - 0.0037 17.5 46.6 0.076 13.3 3.1 5.7 5 0 0 5 5 5 3 EGF-like domain EGF_Tenascin PF18720.1 KDO30749.1 - 0.07 13.2 50.0 0.37 10.9 7.4 5.5 5 0 0 5 5 5 0 Tenascin EGF domain hEGF PF12661.7 KDO30749.1 - 0.082 13.6 0.9 0.082 13.6 0.9 6.0 5 0 0 5 5 5 0 Human growth factor-like EGF Peptidase_S24 PF00717.23 KDO30750.1 - 1.4e-09 37.7 0.1 3.1e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KDO30750.1 - 0.011 15.6 0.0 2.8 7.7 0.0 2.7 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Uma2 PF05685.12 KDO30750.1 - 0.038 13.5 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative restriction endonuclease PIG-P PF08510.12 KDO30751.1 - 3.9e-34 117.1 6.7 5.7e-34 116.6 6.7 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KDO30751.1 - 3.4e-05 24.1 6.6 5.5e-05 23.4 6.6 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) FixQ PF05545.11 KDO30751.1 - 0.055 13.5 0.6 0.055 13.5 0.6 2.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF4519 PF15012.6 KDO30751.1 - 6.8 6.9 6.0 0.52 10.5 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) PHP PF02811.19 KDO30752.1 - 3.1e-07 30.9 0.0 3.1e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 PHP domain Pkinase_Tyr PF07714.17 KDO30753.1 - 1.3e-37 129.5 0.0 9.9e-19 67.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO30753.1 - 4.8e-37 127.7 0.0 1.1e-19 70.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain TMEM51 PF15345.6 KDO30753.1 - 0.00084 19.3 0.2 0.0013 18.7 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 TPR_21 PF09976.9 KDO30753.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain EphA2_TM PF14575.6 KDO30753.1 - 0.0088 16.9 0.0 0.019 15.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 KDO30753.1 - 0.0088 15.7 0.5 0.014 15.1 0.5 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RskA PF10099.9 KDO30753.1 - 0.015 15.6 0.0 0.048 14.0 0.0 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TMEM154 PF15102.6 KDO30753.1 - 0.017 15.0 1.2 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF4448 PF14610.6 KDO30753.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Baculo_E56 PF04639.12 KDO30753.1 - 0.025 13.9 0.7 0.064 12.5 0.7 1.6 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope RCR PF12273.8 KDO30753.1 - 0.025 15.2 0.3 0.053 14.2 0.3 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 KDO30753.1 - 0.032 14.5 3.7 0.039 14.2 2.8 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 KDO30753.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_E3_CR2 PF02439.15 KDO30753.1 - 0.038 13.7 0.4 0.073 12.8 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM163 PF15069.6 KDO30753.1 - 0.044 14.2 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 FAM163 family DUF2771 PF10969.8 KDO30753.1 - 0.12 12.4 0.3 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DUF2946 PF11162.8 KDO30753.1 - 0.17 12.6 2.7 0.39 11.4 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) GAPT PF11770.8 KDO30753.1 - 0.17 11.7 0.6 0.94 9.3 0.2 2.1 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Pkinase PF00069.25 KDO30754.1 - 2.2e-52 178.1 0.0 2.9e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30754.1 - 2.3e-50 171.3 0.0 3e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO30754.1 - 0.0014 17.5 0.1 0.002 17.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO30754.1 - 0.0033 16.4 0.0 0.019 13.9 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain DUF2561 PF10812.8 KDO30754.1 - 0.0047 17.0 0.2 0.0092 16.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Kdo PF06293.14 KDO30754.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO30754.1 - 0.047 13.6 0.2 0.81 9.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF443 PF04276.12 KDO30754.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF443) EphA2_TM PF14575.6 KDO30754.1 - 0.13 13.2 0.0 0.25 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 KDO30754.1 - 0.13 12.1 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator MtrF PF09472.10 KDO30754.1 - 0.23 10.9 2.7 0.5 9.8 2.7 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) LETM1 PF07766.13 KDO30755.1 - 4.1e-66 223.1 1.5 4.1e-66 223.1 1.5 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_8 PF13833.6 KDO30755.1 - 2.1e-10 40.3 1.3 8.8e-10 38.3 0.1 2.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO30755.1 - 5.5e-10 38.1 0.6 0.00039 19.8 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KDO30755.1 - 1.8e-08 33.5 4.0 0.00055 19.3 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO30755.1 - 4.4e-08 33.5 5.9 1.2e-07 32.1 0.5 3.8 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO30755.1 - 4.2e-07 29.4 0.6 0.015 15.2 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain DUF5109 PF17134.4 KDO30755.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) SPARC_Ca_bdg PF10591.9 KDO30755.1 - 0.07 13.5 0.1 0.07 13.5 0.1 3.2 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Rotamase PF00639.21 KDO30755.1 - 4.2 8.4 10.2 5.2 8.1 3.0 2.9 3 0 0 3 3 3 0 PPIC-type PPIASE domain IlvC PF01450.19 KDO30756.1 - 6.6e-39 133.5 0.0 3.7e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 KDO30756.1 - 2.7e-34 118.1 0.1 4.5e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UCH PF00443.29 KDO30757.1 - 5.6e-42 144.0 0.0 8.5e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO30757.1 - 4.3e-17 62.7 0.0 8.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 KDO30758.1 - 9.4e-15 54.8 0.0 2.1e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO30758.1 - 3.1e-10 40.4 0.0 8.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KDO30758.1 - 8.8e-08 32.8 0.2 2.7e-07 31.2 0.2 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KDO30758.1 - 0.017 15.2 0.0 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KDO30758.1 - 0.023 15.0 0.5 1.6 9.0 0.1 3.0 1 1 1 2 2 2 0 AAA domain SecA_DEAD PF07517.14 KDO30758.1 - 0.055 12.8 1.1 0.11 11.8 0.1 1.9 3 0 0 3 3 3 0 SecA DEAD-like domain PDZ PF00595.24 KDO30759.1 - 0.007 16.7 0.0 0.54 10.7 0.0 2.3 1 1 1 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KDO30759.1 - 0.094 12.6 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Inositol_P PF00459.25 KDO30761.1 - 2.5e-56 191.2 1.2 3.1e-56 190.9 1.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase_glpX PF03320.13 KDO30761.1 - 0.033 13.0 0.2 0.083 11.7 0.0 1.6 1 1 1 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Spc7 PF08317.11 KDO30762.1 - 0.021 13.7 5.2 0.063 12.1 1.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KDO30762.1 - 0.35 10.9 8.7 5.5 7.1 2.4 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Prp19 PF08606.11 KDO30762.1 - 1.2 9.2 9.0 0.17 11.9 0.4 3.0 2 1 1 3 3 3 0 Prp19/Pso4-like LRR_9 PF14580.6 KDO30764.1 - 1.2e-08 34.7 0.1 3.2e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KDO30764.1 - 1.6e-08 34.2 8.2 2e-06 27.5 3.5 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KDO30764.1 - 6.3e-07 29.6 5.0 0.0016 18.8 0.7 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO30764.1 - 0.13 12.4 3.7 53 4.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat CRA PF06589.11 KDO30764.1 - 0.21 11.7 0.6 0.39 10.8 0.6 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) LRR_1 PF00560.33 KDO30764.1 - 3.2 8.7 6.1 95 4.2 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat RecG_N PF17190.4 KDO30764.1 - 5.8 7.7 11.5 3.2 8.5 0.4 3.7 3 0 0 3 3 3 0 RecG N-terminal helical domain DUF1664 PF07889.12 KDO30765.1 - 0.0047 16.9 1.7 0.0047 16.9 1.7 7.3 7 2 2 9 9 9 3 Protein of unknown function (DUF1664) AAA_6 PF12774.7 KDO30766.1 - 1.4e-132 441.7 0.8 5.8e-132 439.6 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO30766.1 - 2.4e-118 395.7 7.0 2.4e-118 395.7 7.0 3.2 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KDO30766.1 - 5.4e-97 325.8 6.8 5.4e-97 325.8 6.8 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KDO30766.1 - 1.7e-70 236.6 0.0 1.7e-70 236.6 0.0 4.2 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 KDO30766.1 - 9.5e-68 228.3 0.0 3.2e-67 226.6 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KDO30766.1 - 2.7e-42 144.3 0.0 1.5e-33 115.9 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 KDO30766.1 - 2.1e-39 135.5 0.0 6.1e-39 134.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 KDO30766.1 - 4.2e-36 124.7 9.3 4.2e-36 124.7 9.3 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KDO30766.1 - 5.2e-35 120.7 0.0 1.1e-34 119.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO30766.1 - 6.3e-29 100.5 0.0 3.5e-27 94.9 0.0 3.8 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KDO30766.1 - 2.7e-27 95.5 0.0 2.9e-13 50.0 0.0 6.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KDO30766.1 - 5.6e-23 81.4 3.9 2e-22 79.6 0.1 3.8 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KDO30766.1 - 6.1e-15 55.7 0.1 0.0028 17.9 0.0 6.4 5 0 0 5 5 5 4 AAA domain AAA PF00004.29 KDO30766.1 - 1.4e-13 51.5 0.0 0.0053 17.2 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO30766.1 - 2.8e-10 40.8 2.2 0.2 12.0 0.0 7.2 6 0 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.6 KDO30766.1 - 1.7e-08 34.7 0.0 0.038 14.1 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 KDO30766.1 - 5.9e-07 30.1 0.1 0.32 11.5 0.0 5.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 KDO30766.1 - 2.7e-05 23.3 0.0 0.047 12.7 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KDO30766.1 - 3.2e-05 23.9 0.0 3.3 7.6 0.0 3.7 3 0 0 3 3 3 2 RsgA GTPase AAA_25 PF13481.6 KDO30766.1 - 4.6e-05 23.1 2.1 0.1 12.2 0.1 4.7 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 KDO30766.1 - 6.2e-05 23.5 0.0 0.83 10.2 0.0 4.4 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 KDO30766.1 - 7.2e-05 22.3 0.5 0.39 10.1 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KDO30766.1 - 0.00034 20.4 0.4 3.3 7.4 0.0 4.6 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 KDO30766.1 - 0.00048 19.9 0.0 2.7 7.7 0.0 4.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KDO30766.1 - 0.00056 19.7 0.3 21 4.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 KDO30766.1 - 0.00063 19.7 0.1 5.8 6.8 0.0 4.5 4 0 0 4 4 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 KDO30766.1 - 0.0012 19.1 0.1 3.7 8.0 0.0 4.5 4 0 0 4 4 4 1 RNA helicase Fez1 PF06818.15 KDO30766.1 - 0.002 18.6 11.2 0.002 18.6 11.2 4.7 4 0 0 4 4 4 2 Fez1 TsaE PF02367.17 KDO30766.1 - 0.0024 17.9 1.6 7.6 6.6 0.0 4.3 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KDO30766.1 - 0.003 17.3 4.2 0.62 9.8 0.0 4.5 5 0 0 5 5 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KDO30766.1 - 0.0047 16.3 0.5 2.1 7.7 0.0 4.3 4 0 0 4 4 4 1 FtsK/SpoIIIE family NACHT PF05729.12 KDO30766.1 - 0.0058 16.6 0.1 20 5.1 0.0 4.2 3 0 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.26 KDO30766.1 - 0.0086 15.8 0.0 7.8 6.2 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 KDO30766.1 - 0.0097 15.6 0.0 11 5.8 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KDO30766.1 - 0.0097 16.2 8.0 0.17 12.2 0.0 4.7 5 0 0 5 5 3 1 AAA domain AAA_lid_1 PF17857.1 KDO30766.1 - 0.022 15.0 0.1 0.099 12.9 0.1 2.2 1 0 0 1 1 1 0 AAA+ lid domain Guanylate_kin PF00625.21 KDO30766.1 - 0.05 13.3 0.2 44 3.7 0.0 4.0 3 0 0 3 3 3 0 Guanylate kinase DUF4775 PF16001.5 KDO30766.1 - 1.9 7.8 6.5 4 6.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) DUF4122 PF13498.6 KDO30766.1 - 2.4 7.8 9.7 0.42 10.3 5.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4122) Kin17_mid PF10357.9 KDO30767.1 - 5.7e-50 168.5 2.6 5.7e-50 168.5 2.6 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KDO30767.1 - 6.7e-23 80.6 6.7 1.3e-22 79.6 6.7 1.5 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-C2H2_jaz PF12171.8 KDO30767.1 - 9.4e-07 29.0 2.5 2e-06 27.9 2.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO30767.1 - 5.7e-05 23.4 2.9 0.00011 22.4 2.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KDO30767.1 - 0.00035 20.9 2.2 0.0012 19.1 0.3 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KDO30767.1 - 0.19 12.6 1.0 0.66 11.0 1.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger AKAP95 PF04988.12 KDO30767.1 - 6.5 7.0 7.8 0.22 11.7 0.6 2.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) THOC7 PF05615.13 KDO30768.1 - 2.3e-11 44.1 0.1 2.3e-11 44.1 0.1 1.7 2 1 0 2 2 2 1 Tho complex subunit 7 zf-B_box PF00643.24 KDO30769.1 - 4.1e-11 42.9 18.7 1.2e-08 34.9 4.2 2.4 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 KDO30769.1 - 0.0012 18.4 0.1 0.14 11.7 0.2 2.7 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF4531 PF15041.6 KDO30769.1 - 0.018 15.1 0.0 0.067 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) zf-Mss51 PF13824.6 KDO30769.1 - 0.13 12.4 3.9 0.34 11.0 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 IBR PF01485.21 KDO30769.1 - 1.8 8.9 13.7 3.2 8.1 3.3 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ank_4 PF13637.6 KDO30770.1 - 9.7e-22 77.1 6.0 2.7e-07 31.0 0.2 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO30770.1 - 1.1e-18 67.6 7.2 2.6e-07 31.1 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO30770.1 - 6.9e-15 53.7 11.6 0.00067 19.9 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KDO30770.1 - 1.2e-14 54.0 13.2 0.00028 21.2 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO30770.1 - 5.1e-14 52.2 9.6 2.3e-06 27.8 0.2 5.1 3 2 1 4 4 4 3 Ankyrin repeats (many copies) IQ_SEC7_PH PF16453.5 KDO30770.1 - 0.015 15.2 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 PH domain zf-B_box PF00643.24 KDO30770.1 - 5.1 7.3 7.4 1.3 9.2 3.1 2.2 2 0 0 2 2 2 0 B-box zinc finger DUF547 PF04784.14 KDO30771.1 - 3e-19 69.2 0.0 6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 WHH PF14414.6 KDO30771.1 - 0.14 12.0 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH CAP_N PF01213.19 KDO30771.1 - 7 6.0 4.9 12 5.3 4.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal B9-C2 PF07162.11 KDO30772.1 - 3.1e-16 60.0 0.0 5.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein EF-hand_1 PF00036.32 KDO30773.1 - 2e-32 108.3 18.8 9e-09 34.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO30773.1 - 3.9e-28 97.7 10.9 1.3e-14 54.4 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO30773.1 - 4.6e-25 85.4 9.8 3.2e-09 36.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KDO30773.1 - 7.2e-23 80.2 17.1 6.8e-13 48.3 1.6 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KDO30773.1 - 6.9e-13 48.7 0.2 1.6e-06 28.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO30773.1 - 2.2e-12 45.9 15.2 1e-05 24.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 KDO30773.1 - 0.00013 21.9 11.1 5.3 7.1 0.0 4.1 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 KDO30773.1 - 0.00037 20.3 1.0 0.0021 17.8 0.4 2.0 2 0 0 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KDO30773.1 - 0.00087 19.6 1.6 0.24 11.8 0.2 2.6 1 1 1 2 2 2 1 EF-hand domain DUF3911 PF13050.6 KDO30773.1 - 0.0022 18.0 5.7 0.063 13.4 0.5 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3911) Caleosin PF05042.13 KDO30773.1 - 0.0034 17.3 1.6 2.3 8.1 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein LETM1 PF07766.13 KDO30773.1 - 0.0068 15.8 2.3 0.11 11.8 1.8 2.2 1 1 1 2 2 2 1 LETM1-like protein SurA_N_2 PF13623.6 KDO30773.1 - 0.0077 16.1 2.3 0.68 9.8 0.2 2.6 1 1 1 2 2 2 2 SurA N-terminal domain Toprim_2 PF13155.6 KDO30773.1 - 0.012 16.0 1.2 2.9 8.4 0.2 2.7 1 1 2 3 3 3 0 Toprim-like TerB PF05099.13 KDO30773.1 - 0.013 15.5 2.5 0.026 14.5 0.5 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB SUB1_ProdP9 PF18213.1 KDO30773.1 - 0.016 15.0 2.4 0.018 14.9 0.6 2.0 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 PepSY_2 PF13670.6 KDO30773.1 - 0.029 14.4 4.2 1 9.4 0.1 2.7 2 1 1 3 3 2 0 Peptidase propeptide and YPEB domain DUF5580 PF17743.1 KDO30773.1 - 0.034 12.7 0.0 1.9 6.9 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5580) EF-hand_11 PF08976.11 KDO30773.1 - 0.034 15.0 1.6 1.4 9.9 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain ERAP1_C PF11838.8 KDO30773.1 - 0.035 13.6 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain DUF4712 PF15830.5 KDO30773.1 - 0.039 13.7 1.3 3.2 7.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4712) Gp-FAR-1 PF05823.12 KDO30773.1 - 0.062 13.7 2.3 0.18 12.2 0.0 2.6 1 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Leucyl-specific PF14795.6 KDO30773.1 - 0.15 12.2 0.3 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain YolD PF08863.10 KDO30773.1 - 0.41 10.7 0.1 0.41 10.7 0.1 2.6 3 1 0 3 3 3 0 YolD-like protein zf-RING_2 PF13639.6 KDO30774.1 - 3e-12 46.7 6.4 5.7e-12 45.8 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO30774.1 - 3.8e-12 45.8 5.7 7.4e-12 44.9 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KDO30774.1 - 3.7e-11 42.9 0.3 1e-10 41.5 0.4 1.7 2 0 0 2 2 1 1 PA domain zf-C3HC4 PF00097.25 KDO30774.1 - 1.9e-10 40.4 3.8 3.3e-10 39.7 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO30774.1 - 5.3e-10 38.9 2.8 1.2e-09 37.7 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO30774.1 - 1.9e-08 34.4 8.2 2e-07 31.2 8.0 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO30774.1 - 4.2e-07 29.9 2.9 4.3e-07 29.8 1.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO30774.1 - 5e-06 26.4 3.0 8.5e-06 25.6 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO30774.1 - 1.6e-05 24.7 1.6 2.6e-05 24.0 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO30774.1 - 0.00014 21.9 6.8 0.0017 18.4 5.6 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO30774.1 - 0.00039 20.2 3.4 0.00083 19.2 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KDO30774.1 - 0.0078 16.4 4.7 0.015 15.4 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KDO30774.1 - 0.014 15.1 5.0 0.032 14.0 5.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KDO30774.1 - 0.014 15.5 3.5 0.014 15.5 3.5 2.1 2 1 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KDO30774.1 - 0.022 15.1 3.5 0.048 14.0 3.5 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KDO30774.1 - 0.05 13.5 4.7 0.1 12.5 4.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 KDO30774.1 - 0.067 13.0 1.4 0.12 12.2 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KDO30774.1 - 0.096 12.3 4.7 0.21 11.3 4.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2062 PF09835.9 KDO30774.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) zf-HC5HC2H_2 PF13832.6 KDO30774.1 - 0.24 11.6 2.8 0.17 12.0 0.3 2.0 2 1 0 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.8 KDO30774.1 - 2.2 8.5 10.2 11 6.3 8.0 2.9 3 1 0 3 3 1 0 FANCL C-terminal domain Kinesin PF00225.23 KDO30775.1 - 1.5e-91 306.8 0.0 4.2e-91 305.3 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30775.1 - 8.8e-16 58.2 0.0 3.2e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 KDO30775.1 - 0.0005 20.4 0.4 0.0034 17.7 0.0 2.6 3 0 0 3 3 3 1 FHA domain Kinesin_assoc PF16183.5 KDO30775.1 - 0.22 11.6 0.0 0.22 11.6 0.0 5.0 4 3 1 6 6 6 0 Kinesin-associated PhzC-PhzF PF02567.16 KDO30776.1 - 1.5e-62 211.6 0.0 1.9e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 KDO30776.1 - 3.8e-12 46.5 0.0 9.5e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO30776.1 - 1.5e-09 37.9 0.0 4.1e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO30776.1 - 8.8e-07 29.3 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO30776.1 - 4.6e-05 23.5 0.0 7.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KDO30776.1 - 0.0003 20.7 0.2 0.0009 19.2 0.0 1.9 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_8 PF13523.6 KDO30776.1 - 0.09 12.5 0.4 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KDO30776.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 KDO30776.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PhzC-PhzF PF02567.16 KDO30777.1 - 9.1e-63 212.3 0.1 1.1e-62 212.0 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 KDO30777.1 - 7.3e-11 42.3 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO30777.1 - 1.2e-09 38.2 0.0 4.6e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO30777.1 - 2.9e-07 30.8 0.0 7.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO30777.1 - 4.1e-07 30.1 0.0 8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KDO30777.1 - 0.0046 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KDO30777.1 - 0.028 14.5 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KDO30777.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein UCH PF00443.29 KDO30779.1 - 1.1e-31 110.3 0.0 3.4e-31 108.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 KDO30779.1 - 3.1e-13 48.8 45.5 3.8e-05 22.9 4.1 5.2 5 0 0 5 5 5 4 Zn-finger in Ran binding protein and others UCH_1 PF13423.6 KDO30779.1 - 2.3e-09 37.3 0.2 3.1e-05 23.7 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Laminin_G_3 PF13385.6 KDO30779.1 - 1.2e-05 25.5 0.0 4.6e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF2464 PF10240.9 KDO30779.1 - 0.0012 18.5 0.1 7 6.1 0.0 4.0 4 0 0 4 4 4 2 Multivesicular body subunit 12 Pkinase PF00069.25 KDO30780.1 - 9.9e-39 133.3 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30780.1 - 3.7e-22 78.9 0.0 5.8e-22 78.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO30780.1 - 0.0018 17.6 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO30780.1 - 0.0041 16.5 0.4 0.0079 15.6 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO30780.1 - 0.0084 14.9 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO30780.1 - 0.011 14.7 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO30780.1 - 0.02 14.8 0.9 0.02 14.8 0.9 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family MTS PF05175.14 KDO30781.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KDO30781.1 - 0.025 14.3 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase SKN1 PF03935.15 KDO30782.1 - 7.3e-60 202.8 21.2 4.7e-26 91.3 1.5 5.0 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) DUF5454 PF17535.2 KDO30782.1 - 0.22 10.9 0.4 0.37 10.1 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Toxin_2 PF00451.19 KDO30782.1 - 8 6.9 7.3 4.4 7.7 4.1 2.2 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 SKN1 PF03935.15 KDO30784.1 - 5.9e-56 189.9 13.7 4.5e-25 88.0 0.4 5.1 5 1 0 5 5 5 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO30784.1 - 0.0095 16.2 1.9 0.016 15.4 0.7 2.0 2 0 0 2 2 2 1 EB module EGF_2 PF07974.13 KDO30784.1 - 0.53 10.7 6.8 1.5 9.3 6.8 1.8 1 0 0 1 1 1 0 EGF-like domain SKN1 PF03935.15 KDO30785.1 - 6.4e-58 196.4 19.1 1.2e-23 83.3 0.7 5.0 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO30785.1 - 0.07 13.4 3.5 0.14 12.5 2.1 2.1 2 0 0 2 2 2 0 EB module EGF_2 PF07974.13 KDO30785.1 - 3.1 8.2 8.3 11 6.5 8.3 2.0 1 0 0 1 1 1 0 EGF-like domain SKN1 PF03935.15 KDO30786.1 - 3.3e-56 190.8 21.9 3.1e-25 88.6 0.8 5.1 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO30786.1 - 0.088 13.1 2.3 0.18 12.1 1.0 2.1 2 0 0 2 2 2 0 EB module SKN1 PF03935.15 KDO30787.1 - 4.7e-59 200.1 18.4 8.6e-26 90.4 0.3 5.0 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 KDO30787.1 - 0.051 13.9 2.7 0.086 13.1 1.0 2.3 2 0 0 2 2 2 0 EB module Aa_trans PF01490.18 KDO30788.1 - 1.2e-49 169.1 34.9 3.9e-44 151.0 21.7 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO30788.1 - 1.9e-05 23.9 29.1 7.6e-05 21.9 26.2 2.0 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family PsbJ PF01788.17 KDO30788.1 - 0.17 11.8 0.3 0.17 11.8 0.3 3.7 3 0 0 3 3 3 0 PsbJ TPR_2 PF07719.17 KDO30789.1 - 2.6e-09 36.5 19.2 0.19 12.0 0.0 8.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30789.1 - 4e-08 32.7 16.6 0.022 14.6 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO30789.1 - 4.6e-05 23.0 2.7 0.027 14.2 0.0 5.3 6 0 0 6 6 6 1 TPR repeat TPR_19 PF14559.6 KDO30789.1 - 0.00029 21.3 10.5 0.18 12.4 0.1 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO30789.1 - 0.00055 20.0 6.7 0.0061 16.7 0.1 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30789.1 - 0.0087 16.2 6.4 28 5.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO30789.1 - 0.0099 16.5 0.3 0.0099 16.5 0.3 5.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO30789.1 - 0.21 11.7 4.4 27 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO30789.1 - 1.6 9.3 5.6 17 6.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO30789.1 - 3.2 8.1 19.4 0.88 9.9 0.2 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KDO30790.1 - 8.3e-45 153.5 22.0 1.2e-44 153.0 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO30790.1 - 1.3e-35 123.0 40.4 5.2e-35 121.0 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO30790.1 - 1.8e-05 23.4 1.8 2.6e-05 22.8 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KDO30790.1 - 4.6e-05 22.9 3.2 4.6e-05 22.9 3.2 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DpnII-MboI PF18742.1 KDO30790.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 REase_DpnII-MboI Cation_ATPase_C PF00689.21 KDO30790.1 - 5.4 6.7 10.5 1.2 8.9 6.1 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus zf-C2H2_jaz PF12171.8 KDO30792.1 - 0.0033 17.7 0.2 0.0062 16.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO30792.1 - 0.0085 16.5 0.1 0.022 15.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KDO30792.1 - 0.16 12.5 0.7 0.42 11.2 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type PP2C PF00481.21 KDO30793.1 - 1.6e-48 165.6 0.0 1.5e-47 162.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 KDO30793.1 - 6e-14 52.4 0.1 1.4e-13 51.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO30793.1 - 7e-05 23.2 0.2 0.00033 21.1 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Nramp PF01566.18 KDO30794.1 - 2.7e-114 381.9 14.4 3.9e-114 381.4 14.4 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein TPD52 PF04201.15 KDO30796.1 - 0.022 14.4 0.9 0.022 14.4 0.9 6.0 3 3 4 7 7 7 0 Tumour protein D52 family DUF1803 PF08820.10 KDO30796.1 - 0.025 14.6 0.5 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) Fez1 PF06818.15 KDO30796.1 - 0.029 14.8 80.5 0.052 14.0 9.9 4.6 2 1 2 4 4 4 0 Fez1 DUF211 PF02680.14 KDO30796.1 - 0.095 12.9 0.1 3.7 7.8 0.0 3.4 3 1 0 3 3 3 0 Uncharacterized ArCR, COG1888 Transglut_N PF00868.20 KDO30796.1 - 0.11 12.9 3.3 0.19 12.1 1.3 2.4 1 1 0 1 1 1 0 Transglutaminase family ParA PF10609.9 KDO30798.1 - 2.7e-94 315.2 0.4 7.6e-84 281.0 1.1 2.0 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KDO30798.1 - 1.3e-12 47.9 0.0 1.1e-11 44.9 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KDO30798.1 - 3.3e-09 36.9 0.4 8.6e-08 32.3 0.4 2.2 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KDO30798.1 - 2.3e-07 30.3 4.3 7.1e-07 28.7 1.1 2.3 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KDO30798.1 - 3.6e-07 29.7 0.0 1.4e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KDO30798.1 - 1.1e-05 25.0 0.2 0.0044 16.5 0.1 2.9 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KDO30798.1 - 0.0017 17.8 0.1 0.016 14.7 0.1 2.1 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KDO30798.1 - 0.0044 16.6 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KDO30798.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 KDO30798.1 - 0.0057 15.7 0.3 0.0091 15.0 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KDO30798.1 - 0.015 14.5 0.7 0.023 13.9 0.7 1.3 1 0 0 1 1 1 0 NB-ARC domain PcrB PF01884.17 KDO30798.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 PcrB family AAA_26 PF13500.6 KDO30798.1 - 0.033 14.0 0.8 0.82 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KDO30798.1 - 0.11 12.3 0.3 0.44 10.3 0.3 2.2 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4678 PF15727.5 KDO30798.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) RsgA_GTPase PF03193.16 KDO30798.1 - 0.13 12.2 1.5 0.33 10.8 0.3 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KDO30798.1 - 0.14 12.7 0.0 0.24 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DIRP PF06584.13 KDO30799.1 - 3.5e-24 85.0 0.2 7.3e-24 84.0 0.2 1.6 1 0 0 1 1 1 1 DIRP DUF5519 PF17648.1 KDO30799.1 - 0.0075 16.1 0.1 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5519) PIP5K PF01504.18 KDO30800.1 - 3.6e-36 124.8 0.4 7.2e-36 123.8 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 KDO30800.1 - 0.0025 17.3 11.6 0.0091 15.4 11.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Phage_holin_3_6 PF07332.11 KDO30800.1 - 0.015 15.3 1.5 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_S5 PF00333.20 KDO30801.1 - 2.4e-28 97.9 1.9 4.7e-28 97.0 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KDO30801.1 - 1.4e-26 91.7 0.0 2.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KDO30801.1 - 1.5 9.4 10.8 2.7 8.6 10.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MerE PF05052.12 KDO30802.1 - 0.005 16.7 1.7 0.005 16.7 1.7 2.3 2 0 0 2 2 2 1 MerE protein PMP22_Claudin PF00822.20 KDO30802.1 - 0.0089 15.9 1.3 0.023 14.6 1.3 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family HupE_UreJ_2 PF13795.6 KDO30802.1 - 0.013 15.1 4.9 0.041 13.5 1.5 2.4 2 1 0 2 2 2 0 HupE / UreJ protein LSM PF01423.22 KDO30803.1 - 4.1e-21 74.5 0.6 6.7e-21 73.8 0.6 1.4 1 0 0 1 1 1 1 LSM domain BT1 PF03092.16 KDO30804.1 - 4.8e-10 38.3 14.4 7.8e-09 34.3 6.1 3.1 2 1 0 2 2 2 2 BT1 family PUCC PF03209.15 KDO30804.1 - 1.2e-06 27.8 9.0 1.4e-05 24.3 2.4 2.8 2 2 0 2 2 2 2 PUCC protein RbsD_FucU PF05025.13 KDO30805.1 - 2.9e-35 121.6 0.0 3.3e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family Nucleoside_tran PF01733.18 KDO30806.1 - 9.4e-17 61.3 11.8 9.7e-16 58.0 11.8 2.1 1 1 0 1 1 1 1 Nucleoside transporter Sugar_tr PF00083.24 KDO30806.1 - 0.00016 20.7 26.4 0.00049 19.1 16.9 2.6 1 1 1 3 3 3 3 Sugar (and other) transporter Nucleoside_tran PF01733.18 KDO30807.1 - 2e-19 70.1 15.1 1.9e-18 66.9 15.1 2.1 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KDO30807.1 - 1.8e-06 27.1 4.7 1.8e-06 27.1 4.7 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily SieB PF14163.6 KDO30807.1 - 0.56 9.7 3.0 0.38 10.2 0.3 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B TssO PF17561.2 KDO30807.1 - 8.6 6.5 5.4 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO Nucleoside_tran PF01733.18 KDO30808.1 - 1e-19 71.1 12.4 1.2e-18 67.6 12.4 2.2 1 1 0 1 1 1 1 Nucleoside transporter TssO PF17561.2 KDO30808.1 - 0.11 12.5 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF2663 PF10864.8 KDO30808.1 - 7.4 7.0 9.4 16 5.9 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Nucleoside_tran PF01733.18 KDO30809.1 - 1.2e-20 74.2 8.1 8.5e-20 71.3 8.1 2.1 1 1 0 1 1 1 1 Nucleoside transporter DUF2973 PF11189.8 KDO30809.1 - 0.01 15.9 0.2 3.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) DUF2721 PF11026.8 KDO30809.1 - 1.1 9.1 4.4 3 7.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Nup188 PF10487.9 KDO30810.1 - 0.025 12.5 0.1 0.12 10.2 0.0 2.1 3 0 0 3 3 3 0 Nucleoporin subcomplex protein binding to Pom34 Nse4_C PF08743.10 KDO30811.1 - 1.2e-19 70.4 0.0 3.1e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Glyoxalase_4 PF13669.6 KDO30813.1 - 8.6e-20 71.0 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KDO30813.1 - 0.057 13.6 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TGT PF01702.18 KDO30814.1 - 6.7e-126 420.2 0.0 4.8e-125 417.3 0.0 1.8 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase YgbA_NO PF11756.8 KDO30814.1 - 0.19 12.1 0.6 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter CIA30 PF08547.12 KDO30815.1 - 6.7e-34 117.2 0.0 8.3e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Trm112p PF03966.16 KDO30816.1 - 4.1e-14 52.9 0.0 4.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein adh_short_C2 PF13561.6 KDO30817.1 - 3.1e-56 190.6 0.5 4e-56 190.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO30817.1 - 1.3e-46 158.5 0.2 1.8e-46 158.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO30817.1 - 2e-08 34.4 0.1 3.9e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KDO30817.1 - 2.4e-05 23.6 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KDO30817.1 - 0.0069 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KDO30817.1 - 0.011 15.9 0.1 0.043 14.1 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KDO30817.1 - 0.03 13.8 0.1 0.039 13.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KDO30817.1 - 0.057 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KDO30817.1 - 0.092 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KDO30817.1 - 0.095 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SAS-6_N PF16531.5 KDO30818.1 - 1.1e-25 90.0 2.6 1.9e-25 89.2 2.6 1.4 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal DUF1493 PF07377.12 KDO30820.1 - 5.8 7.4 10.4 5.1 7.6 1.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1493) Pox_A_type_inc PF04508.12 KDO30821.1 - 0.089 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat RNA_pol_Rpb2_6 PF00562.28 KDO30822.1 - 4.2e-114 381.6 0.8 8.5e-114 380.6 0.8 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KDO30822.1 - 1.2e-36 126.1 0.0 2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KDO30822.1 - 1.4e-28 98.9 0.0 3.1e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KDO30822.1 - 2.8e-21 75.7 0.6 7.8e-21 74.3 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KDO30822.1 - 1.1e-16 61.0 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KDO30822.1 - 2.3e-10 40.3 0.0 4.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain DUF2688 PF10892.8 KDO30822.1 - 0.19 11.2 1.3 0.52 9.8 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Pellino PF04710.14 KDO30823.1 - 2.7e-41 141.6 0.0 1.1e-20 73.7 0.3 2.3 2 0 0 2 2 2 2 Pellino zf-C3HC4_3 PF13920.6 KDO30823.1 - 0.00034 20.4 16.7 0.03 14.2 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO30823.1 - 0.1 12.9 20.2 0.09 13.1 3.5 3.5 3 1 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.6 KDO30823.1 - 0.75 9.7 21.1 0.15 12.0 3.5 3.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KDO30823.1 - 0.86 9.5 12.2 2.4 8.1 1.9 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO30823.1 - 5.3 7.4 13.5 3 8.2 1.7 3.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain GIT_CC PF16559.5 KDO30824.1 - 4.4 7.3 17.4 5.2 7.0 0.7 4.8 3 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor fn3 PF00041.21 KDO30825.1 - 1.4e-12 47.8 0.0 9.9e-06 25.8 0.0 3.6 2 2 0 2 2 2 2 Fibronectin type III domain WD40 PF00400.32 KDO30825.1 - 5.3e-10 39.7 13.6 0.11 13.4 0.0 7.3 6 1 0 6 6 6 4 WD domain, G-beta repeat TPR_12 PF13424.6 KDO30825.1 - 3.3e-09 36.9 4.1 4.5e-08 33.3 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat LysM PF01476.20 KDO30825.1 - 9.7e-06 25.6 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain TPR_2 PF07719.17 KDO30825.1 - 4e-05 23.4 0.0 0.0091 16.0 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO30825.1 - 0.00016 22.2 1.0 0.019 15.6 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO30825.1 - 0.00023 21.1 0.2 0.0069 16.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO30825.1 - 0.0014 18.4 0.1 0.0077 16.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO30825.1 - 0.013 15.3 0.3 0.13 12.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 KDO30827.1 - 7.2e-07 29.7 1.3 0.001 19.6 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO30827.1 - 0.00017 22.1 0.3 0.035 14.7 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO30827.1 - 0.045 14.1 3.1 21 5.6 0.0 3.9 2 2 2 4 4 4 0 Ankyrin repeats (many copies) FolB PF02152.18 KDO30827.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase Pkinase_Tyr PF07714.17 KDO30828.1 - 4.4e-34 117.9 0.0 2.7e-32 112.1 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30828.1 - 1.8e-33 116.1 0.0 1.5e-32 113.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO30828.1 - 0.0098 14.9 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Abhydrolase_1 PF00561.20 KDO30829.1 - 1.2e-21 77.5 0.2 1.1e-20 74.3 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO30829.1 - 1.6e-17 63.5 0.1 5.5e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KDO30829.1 - 0.0016 17.8 0.0 0.14 11.4 0.0 3.2 3 1 1 4 4 4 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO30830.1 - 3.8e-21 75.9 0.0 1.5e-20 73.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KDO30830.1 - 8.2e-13 48.4 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF1336 PF07059.12 KDO30831.1 - 4.6e-55 187.2 0.0 6e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) FAD-oxidase_C PF02913.19 KDO30832.1 - 5e-60 203.2 0.0 7.1e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KDO30832.1 - 3.2e-36 124.1 0.4 6.2e-36 123.2 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_2 PF12756.7 KDO30833.1 - 3e-31 107.7 16.9 1.4e-26 92.8 5.5 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KDO30833.1 - 0.0016 18.8 2.9 0.0016 18.8 2.9 5.0 5 0 0 5 5 4 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KDO30833.1 - 0.0016 18.3 0.1 0.0048 16.8 0.1 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KDO30833.1 - 0.0023 18.2 6.0 0.0023 18.2 6.0 3.9 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KDO30833.1 - 0.0096 16.7 0.7 0.0096 16.7 0.7 5.4 6 0 0 6 6 4 2 C2H2-type zinc finger zinc_ribbon_10 PF10058.9 KDO30833.1 - 0.014 15.1 2.2 0.6 9.9 0.1 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_6 PF13912.6 KDO30833.1 - 0.02 14.9 16.3 0.027 14.4 2.9 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KDO30833.1 - 0.062 12.9 3.6 4.2 7.0 0.6 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KDO30833.1 - 0.073 13.0 1.2 2 8.4 0.1 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-UBP PF02148.19 KDO30833.1 - 0.15 12.4 4.4 1.8 9.0 2.0 2.8 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 KDO30833.1 - 0.42 10.8 0.1 0.42 10.8 0.1 3.3 4 0 0 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.6 KDO30833.1 - 0.75 10.2 2.8 28 5.2 0.2 3.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-FCS PF06467.14 KDO30833.1 - 1.2 9.2 10.7 0.78 9.7 1.1 3.4 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Gemini_AC4_5_2 PF08464.10 KDO30834.1 - 0.046 13.7 0.2 0.061 13.3 0.2 1.3 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Methyltransf_16 PF10294.9 KDO30835.1 - 1.8e-20 73.4 0.1 2.4e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO30835.1 - 0.0033 17.0 0.1 0.0046 16.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain ATG16 PF08614.11 KDO30837.1 - 8.9e-08 32.6 17.3 8.9e-08 32.6 17.3 8.0 2 2 5 7 7 7 1 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KDO30837.1 - 9e-05 22.4 27.1 0.0011 18.9 12.4 6.8 5 1 2 7 7 7 2 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KDO30837.1 - 0.00022 20.3 8.4 0.00022 20.3 8.4 6.7 4 1 3 8 8 8 3 Spc7 kinetochore protein BST2 PF16716.5 KDO30837.1 - 0.0095 16.5 8.2 0.0095 16.5 8.2 8.7 5 2 5 10 10 10 1 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 KDO30837.1 - 0.023 15.6 9.1 0.023 15.6 9.1 8.0 6 3 2 8 8 8 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 KDO30837.1 - 0.13 12.7 74.7 1.3 9.5 13.9 6.6 1 1 3 4 4 4 0 Fez1 DivIC PF04977.15 KDO30837.1 - 1.1 9.1 0.0 1.1 9.1 0.0 11.6 10 3 4 14 14 14 0 Septum formation initiator ADIP PF11559.8 KDO30837.1 - 4.6 7.3 89.6 0.78 9.8 13.5 9.8 4 2 7 11 11 11 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 KDO30837.1 - 5.7 7.1 43.6 6.4 7.0 0.1 11.4 13 1 0 13 13 13 0 bZIP transcription factor EF-hand_1 PF00036.32 KDO30839.1 - 1.4e-13 49.3 7.1 0.00015 21.1 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KDO30839.1 - 2.6e-10 39.4 6.4 0.014 15.3 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KDO30839.1 - 9.2e-10 38.8 4.5 0.00015 22.2 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO30839.1 - 1.4e-09 37.0 4.4 0.014 14.9 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KDO30839.1 - 3.5e-05 23.6 4.5 1 9.3 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KDO30839.1 - 0.021 14.8 0.8 0.21 11.5 0.0 2.5 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Sugar_tr PF00083.24 KDO30842.1 - 1.1e-30 106.9 28.9 9.2e-18 64.3 5.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO30842.1 - 4.6e-19 68.6 39.2 1.1e-16 60.7 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO30842.1 - 0.00018 20.1 1.9 0.00018 20.1 1.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 KDO30842.1 - 6.9 7.2 6.1 6.7 7.2 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Radical_SAM PF04055.21 KDO30843.1 - 5.5e-14 52.9 0.0 1.3e-13 51.7 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KDO30843.1 - 0.0016 18.5 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain BBS1 PF14779.6 KDO30843.1 - 0.058 12.8 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 PAM2 PF07145.15 KDO30844.1 - 1.3 8.9 5.5 0.29 10.9 0.8 2.4 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DSPc PF00782.20 KDO30846.1 - 1.3e-11 44.5 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 KDO30846.1 - 4.2e-05 24.0 0.0 7.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DUF4518 PF15008.6 KDO30846.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Y_phosphatase PF00102.27 KDO30846.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IQ PF00612.27 KDO30847.1 - 9.5e-15 52.9 19.1 0.0004 19.9 0.1 6.5 5 0 0 5 5 5 5 IQ calmodulin-binding motif UCH PF00443.29 KDO30848.1 - 1.5e-39 136.1 0.0 2.7e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KDO30848.1 - 1.4e-18 66.4 0.0 5.7e-18 64.4 0.0 2.1 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KDO30848.1 - 1.6e-16 59.8 2.2 7.6e-08 32.1 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KDO30848.1 - 8.6e-14 51.6 0.0 4.5e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KDO30848.1 - 1e-12 48.3 0.2 3e-09 36.9 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3173 PF11372.8 KDO30848.1 - 0.058 13.3 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) WD40 PF00400.32 KDO30849.1 - 5.8e-10 39.6 0.7 0.01 16.7 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30849.1 - 0.00081 19.6 0.0 8.4 6.8 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 KDO30851.1 - 1.6e-57 192.0 10.1 3.6e-09 37.1 0.2 10.2 5 5 4 9 9 9 8 Ankyrin repeats (3 copies) zf-TRAF PF02176.18 KDO30851.1 - 5.2e-52 174.4 231.9 1.9e-06 28.5 9.2 20.5 6 6 16 22 22 22 20 TRAF-type zinc finger Ank_4 PF13637.6 KDO30851.1 - 7.1e-44 147.6 15.8 1.9e-08 34.7 0.1 11.3 8 3 2 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO30851.1 - 3.6e-38 125.2 16.1 0.00027 21.1 0.0 15.7 16 0 0 16 16 16 7 Ankyrin repeat Ank PF00023.30 KDO30851.1 - 5.3e-33 112.0 27.8 0.00083 19.7 0.1 14.6 15 0 0 15 15 15 8 Ankyrin repeat Ank_5 PF13857.6 KDO30851.1 - 1.1e-31 108.4 20.0 1.2e-06 28.6 0.0 11.9 10 2 3 13 13 13 8 Ankyrin repeats (many copies) DUF713 PF05218.14 KDO30851.1 - 0.054 13.2 0.9 0.25 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF713) UBZ_FAAP20 PF15750.5 KDO30851.1 - 1.3 9.0 6.4 5.3 7.1 0.3 4.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger DUF1619 PF07773.11 KDO30852.1 - 2.9e-32 112.9 1.4 1.8e-30 107.0 0.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) Cpn60_TCP1 PF00118.24 KDO30853.1 - 3.5e-150 500.9 16.1 4e-150 500.7 16.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcrB PF01884.17 KDO30853.1 - 0.0093 15.4 1.9 4.1 6.8 0.1 2.9 2 1 0 2 2 2 2 PcrB family DUF2150 PF09920.9 KDO30853.1 - 0.14 12.1 2.2 0.27 11.2 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Abhydrolase_1 PF00561.20 KDO30854.1 - 4.4e-08 33.1 0.0 6.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 KDO30854.1 - 0.00061 18.6 0.0 0.00083 18.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 KDO30854.1 - 0.015 15.4 0.4 0.026 14.6 0.4 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 KDO30854.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KDO30854.1 - 0.032 14.8 6.9 0.097 13.3 6.9 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO30854.1 - 0.11 11.8 0.8 1.9 7.7 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 zf_CCCH_4 PF18345.1 KDO30855.1 - 6.8e-06 26.0 3.6 1.6e-05 24.7 3.6 1.7 1 0 0 1 1 1 1 Zinc finger domain tRNA_anti-codon PF01336.25 KDO30855.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-CCCH PF00642.24 KDO30855.1 - 0.0073 16.2 0.3 0.02 14.8 0.3 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KDO30855.1 - 0.14 12.4 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family PQQ_3 PF13570.6 KDO30856.1 - 7.1e-05 23.2 9.7 2.1 9.0 0.2 4.9 5 0 0 5 5 5 2 PQQ-like domain PQQ_2 PF13360.6 KDO30856.1 - 0.0031 17.1 1.8 0.0057 16.3 0.5 2.1 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KDO30856.1 - 0.0095 15.8 0.2 0.19 11.7 0.1 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat WD40 PF00400.32 KDO30856.1 - 0.014 16.2 1.7 3.2 8.8 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30856.1 - 0.022 15.1 0.0 5.2 7.4 0.0 3.0 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RINGv PF12906.7 KDO30858.1 - 5.6e-15 55.2 6.6 1.3e-14 54.1 6.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KDO30858.1 - 0.005 17.1 4.2 0.013 15.8 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain CAAD PF14159.6 KDO30858.1 - 0.25 11.2 2.3 2.2 8.2 0.4 3.3 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Zn_ribbon_17 PF17120.5 KDO30858.1 - 2.8 7.7 6.0 1.1 8.9 3.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DNA_pol_phi PF04931.13 KDO30858.1 - 5 5.1 5.0 7.5 4.5 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KDO30858.1 - 7.1 5.8 8.1 12 5.1 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_M75 PF09375.10 KDO30859.1 - 0.43 10.0 3.4 0.87 9.0 3.4 1.5 1 0 0 1 1 1 0 Imelysin Kelch_5 PF13854.6 KDO30860.1 - 2.6e-26 91.1 7.2 0.00048 20.1 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KDO30860.1 - 7.1e-25 86.8 18.8 1.3e-06 28.3 0.1 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO30860.1 - 2.7e-23 81.3 9.4 3.9e-05 23.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KDO30860.1 - 1.9e-22 79.0 18.5 1e-05 25.7 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO30860.1 - 1.1e-21 76.3 10.2 0.00024 21.3 0.1 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KDO30860.1 - 1.9e-19 68.8 6.4 0.00084 19.2 0.0 6.2 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.14 KDO30860.1 - 0.0054 15.8 0.0 0.077 12.0 0.0 2.6 3 1 0 3 3 3 1 Recombination activating protein 2 PH PF00169.29 KDO30861.1 - 0.00021 21.8 0.3 0.00049 20.6 0.3 1.7 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 KDO30861.1 - 0.00066 19.8 0.8 0.0032 17.6 0.8 2.0 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.6 KDO30861.1 - 0.0039 17.4 0.2 0.0075 16.5 0.2 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain MMR_HSR1 PF01926.23 KDO30862.1 - 2.5e-07 30.7 0.0 2.9e-06 27.3 0.0 2.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KDO30862.1 - 4.5e-07 30.1 1.7 6.6e-06 26.3 1.7 2.9 1 1 0 1 1 1 1 Dynamin family Tex_N PF09371.10 KDO30862.1 - 0.00083 19.1 0.4 0.0016 18.1 0.4 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Septin PF00735.18 KDO30862.1 - 0.011 15.1 0.5 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KDO30862.1 - 0.013 15.4 1.4 0.17 11.8 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase Roc PF08477.13 KDO30862.1 - 0.023 14.9 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1690 PF07956.11 KDO30862.1 - 0.82 10.1 4.8 0.21 12.0 1.3 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF1161 PF06649.12 KDO30862.1 - 5.1 7.4 5.3 53 4.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1161) GRP PF07172.11 KDO30863.1 - 0.0029 18.3 10.7 0.0048 17.6 10.7 1.3 1 0 0 1 1 1 1 Glycine rich protein family Keratin_2_head PF16208.5 KDO30863.1 - 4.4 7.4 17.7 6.1 7.0 17.7 1.2 1 0 0 1 1 1 0 Keratin type II head LRR_8 PF13855.6 KDO30865.1 - 0.034 13.9 1.3 7.6 6.4 0.2 2.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KDO30865.1 - 0.068 13.6 0.7 0.65 10.5 0.0 2.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Sec15 PF04091.12 KDO30867.1 - 7.5e-35 120.8 0.1 7.5e-34 117.6 0.0 2.6 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps54_N PF10475.9 KDO30867.1 - 0.0026 17.1 0.6 0.0053 16.1 0.6 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 KDO30867.1 - 0.018 14.9 0.1 0.061 13.2 0.1 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Vps51 PF08700.11 KDO30867.1 - 0.045 13.8 0.4 0.39 10.8 0.0 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Apolipoprotein PF01442.18 KDO30867.1 - 0.095 12.6 4.0 0.3 11.0 0.4 3.2 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF1296 PF06972.11 KDO30867.1 - 0.8 9.9 3.4 6.3 7.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Pkinase PF00069.25 KDO30868.1 - 6e-61 206.1 0.0 7.8e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30868.1 - 6.3e-45 153.5 0.0 8.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 KDO30868.1 - 4e-21 75.4 0.0 6.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Pkinase_fungal PF17667.1 KDO30868.1 - 1.6e-05 23.9 0.0 2.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO30868.1 - 0.047 13.6 4.9 1 9.2 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Peptidase_C1 PF00112.23 KDO30869.1 - 5.9e-48 163.8 1.5 7.3e-48 163.5 1.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO30869.1 - 0.0013 17.6 0.4 0.089 11.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Kinesin PF00225.23 KDO30870.1 - 6e-99 331.1 0.1 6e-99 331.1 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO30870.1 - 1.7e-52 177.4 0.0 8.2e-52 175.1 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding HALZ PF02183.18 KDO30870.1 - 1.1 9.5 18.0 1 9.6 1.4 5.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper ALG3 PF05208.13 KDO30871.1 - 2.9e-139 464.5 25.7 4.2e-139 464.0 25.7 1.2 1 0 0 1 1 1 1 ALG3 protein DUF2470 PF10615.9 KDO30871.1 - 0.025 15.2 0.0 0.046 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) Trypsin_2 PF13365.6 KDO30872.1 - 4.5e-15 56.8 0.0 9.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KDO30872.1 - 0.0016 17.2 0.1 0.0024 16.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase S46 Diphthamide_syn PF01866.17 KDO30873.1 - 6.9e-92 308.1 0.0 8.9e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPX2_importin PF12214.8 KDO30874.1 - 0.0012 19.0 1.2 0.0017 18.6 1.2 1.3 1 0 0 1 1 1 1 Cell cycle regulated microtubule associated protein UPF0564 PF10595.9 KDO30874.1 - 0.0091 15.1 0.6 0.012 14.7 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 SWIRM-assoc_1 PF16495.5 KDO30874.1 - 7.2 6.6 7.6 0.7 9.9 1.6 2.1 2 0 0 2 2 2 0 SWIRM-associated region 1 NAD_binding_6 PF08030.12 KDO30875.1 - 1.4e-27 96.7 0.0 1.4e-16 61.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO30875.1 - 8.2e-17 61.3 0.0 2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KDO30875.1 - 1.4e-11 44.6 8.9 3e-11 43.5 8.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KDO30875.1 - 0.0004 21.0 0.0 0.0014 19.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KDO30875.1 - 0.041 14.2 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain APH PF01636.23 KDO30876.1 - 9.4e-14 51.9 0.1 1.2e-13 51.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KDO30876.1 - 4.6e-13 49.1 0.0 3e-11 43.2 0.0 2.3 2 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 KDO30876.1 - 7e-12 44.9 0.1 1e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Orn_Arg_deC_N PF02784.16 KDO30878.1 - 2.2e-75 253.2 0.0 3.8e-75 252.5 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KDO30878.1 - 0.00026 21.2 0.0 0.00057 20.1 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF5029 PF16432.5 KDO30879.1 - 0.068 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) LEA_2 PF03168.13 KDO30879.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF588 PF04535.12 KDO30879.1 - 1.2 8.9 5.1 5.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF588) DUF1348 PF07080.11 KDO30880.1 - 8.4e-57 190.7 1.2 1e-56 190.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KDO30880.1 - 8.1e-10 39.3 2.0 8.1e-10 39.3 2.0 1.5 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 KDO30880.1 - 0.00063 20.1 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Peptidase_M3 PF01432.20 KDO30882.1 - 5.1e-143 477.6 0.0 6.3e-143 477.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KDO30882.1 - 0.042 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M3 PF01432.20 KDO30883.1 - 2.3e-139 465.6 0.0 3.4e-139 465.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KDO30883.1 - 0.046 13.3 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_S41 PF03572.18 KDO30884.1 - 4.3e-16 58.9 0.0 6.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 LMWPc PF01451.21 KDO30886.1 - 2.1e-24 86.5 0.0 2.4e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PGI PF00342.19 KDO30887.1 - 8.2e-194 644.7 0.0 9.4e-194 644.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase OST3_OST6 PF04756.13 KDO30888.1 - 2.1e-16 60.2 0.2 2.6e-16 59.8 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Nucleoporin_C PF03177.14 KDO30889.1 - 1.9e-07 30.3 0.8 5.7e-06 25.4 0.2 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal S-methyl_trans PF02574.16 KDO30889.1 - 0.0068 16.3 0.8 0.015 15.1 0.8 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Chromo PF00385.24 KDO30890.1 - 1.6e-09 37.5 0.1 2.9e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain OATP PF03137.20 KDO30890.1 - 0.0048 15.2 2.7 0.0085 14.4 2.7 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Mtf2_C PF14061.6 KDO30890.1 - 0.061 13.5 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SNN_transmemb PF09049.10 KDO30890.1 - 2.2 8.3 5.5 1 9.4 1.5 2.1 2 0 0 2 2 2 0 Stannin transmembrane Apt1 PF10351.9 KDO30890.1 - 3.2 6.5 6.3 3.7 6.3 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2868 PF11067.8 KDO30890.1 - 3.5 7.0 5.6 2 7.8 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Herpes_pp85 PF04637.12 KDO30890.1 - 4.7 5.5 5.4 2.8 6.2 2.4 1.9 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4614 PF15391.6 KDO30890.1 - 5.2 7.0 11.0 8.6 6.3 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Cpn60_TCP1 PF00118.24 KDO30891.1 - 5.5e-146 487.0 9.5 6.3e-146 486.8 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_TL5_C PF14693.6 KDO30892.1 - 1.2e-17 64.1 0.1 2.8e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 KDO30892.1 - 3.9e-16 59.3 0.0 7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family HMG_box PF00505.19 KDO30893.1 - 5e-20 71.7 0.2 5e-20 71.7 0.2 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.23 KDO30893.1 - 7.6e-20 71.0 0.1 1.7e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box_2 PF09011.10 KDO30893.1 - 2e-10 41.1 0.1 5e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain Histone PF00125.24 KDO30893.1 - 1.3e-05 25.6 0.0 1.3e-05 25.6 0.0 2.2 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CHDNT PF08073.12 KDO30893.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF621 PF04789.15 KDO30894.1 - 4.8 6.2 10.0 8.6 5.4 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) CrgA PF06781.12 KDO30895.1 - 2.8 8.0 4.7 13 5.9 0.9 2.8 2 0 0 2 2 2 0 Cell division protein CrgA LRR_6 PF13516.6 KDO30896.1 - 1.2e-05 24.9 13.5 1.5 9.1 0.0 7.4 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 KDO30896.1 - 3.1e-05 24.2 5.6 0.031 14.7 0.0 5.0 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO30896.1 - 0.0078 16.0 9.4 0.088 12.6 1.2 5.2 4 2 3 7 7 7 2 Leucine rich repeat LRR_8 PF13855.6 KDO30899.1 - 6.6e-07 29.0 0.0 0.00031 20.5 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat IQ PF00612.27 KDO30899.1 - 4.3e-06 26.0 27.8 0.044 13.6 0.7 5.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif LRR_4 PF12799.7 KDO30899.1 - 1.7e-05 25.0 0.0 0.0032 17.9 0.0 3.5 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO30899.1 - 0.00014 21.4 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KDO30899.1 - 0.098 12.8 0.4 47 4.4 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Beta_elim_lyase PF01212.21 KDO30900.1 - 5.3e-96 321.3 0.7 7e-96 320.9 0.7 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KDO30900.1 - 9.2e-12 44.8 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KDO30900.1 - 3.4e-10 39.8 0.7 2.1e-08 33.9 0.7 2.2 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KDO30900.1 - 3.4e-05 22.7 0.0 6.9e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KDO30900.1 - 0.00048 18.8 0.1 0.00071 18.2 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Uteroglobin PF01099.17 KDO30901.1 - 0.28 11.5 2.1 0.75 10.2 2.1 1.7 1 0 0 1 1 1 0 Uteroglobin family Recombinase PF07508.13 KDO30901.1 - 0.36 11.2 0.1 0.36 11.2 0.1 3.3 2 2 1 3 3 3 0 Recombinase Cas9_PI PF16595.5 KDO30901.1 - 3.2 7.5 6.4 4.1 7.2 0.0 2.5 2 1 0 2 2 2 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 TF_Zn_Ribbon PF08271.12 KDO30903.1 - 0.088 12.3 0.9 0.31 10.6 0.6 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Methyltr_RsmF_N PF17125.5 KDO30903.1 - 0.099 13.2 0.2 1.4 9.4 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF MCPVI PF02993.14 KDO30903.1 - 0.45 10.3 9.8 0.18 11.6 7.0 1.7 1 1 1 2 2 2 0 Minor capsid protein VI zf-C2H2_3 PF13878.6 KDO30903.1 - 2 8.3 4.3 1.8 8.4 1.2 2.3 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO 2OG-FeII_Oxy PF03171.20 KDO30905.1 - 6.6e-06 26.5 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PP2C PF00481.21 KDO30906.1 - 1.9e-62 211.2 0.0 2.2e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C ADH_zinc_N_2 PF13602.6 KDO30907.1 - 3.3e-18 67.0 0.0 6.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KDO30907.1 - 4.4e-16 59.1 0.2 8.2e-16 58.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KDO30907.1 - 3.3e-09 36.6 0.0 1.1e-07 31.7 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain C2 PF00168.30 KDO30908.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain BRX_N PF13713.6 KDO30908.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Pkinase PF00069.25 KDO30909.1 - 1.1e-25 90.5 0.0 2.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO30909.1 - 1.1e-19 70.8 0.0 1.7e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KDO30909.1 - 0.00059 19.2 0.9 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HrpJ PF07201.11 KDO30909.1 - 0.003 17.9 0.2 0.003 17.9 0.2 2.0 2 1 0 2 2 2 1 HrpJ-like domain Fez1 PF06818.15 KDO30909.1 - 0.022 15.2 3.7 0.43 11.0 0.0 2.6 3 0 0 3 3 3 0 Fez1 DUF148 PF02520.17 KDO30909.1 - 0.05 13.7 2.3 0.11 12.6 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 FAM184 PF15665.5 KDO30909.1 - 0.095 12.5 6.7 0.24 11.1 6.7 1.7 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B PKK PF12474.8 KDO30909.1 - 0.19 11.9 5.8 0.41 10.8 5.8 1.5 1 0 0 1 1 1 0 Polo kinase kinase Sod_Ni PF09055.11 KDO30909.1 - 0.25 11.9 0.1 0.25 11.9 0.1 2.5 3 1 0 3 3 3 0 Nickel-containing superoxide dismutase ZnuA PF01297.17 KDO30909.1 - 0.28 10.6 0.1 0.28 10.6 0.1 2.3 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic Pkinase_Tyr PF07714.17 KDO30910.1 - 1.2e-24 87.0 0.0 4.7e-24 85.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO30910.1 - 3.9e-24 85.4 0.7 1.2e-23 83.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KDO30910.1 - 0.00057 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TetR_C_24 PF17932.1 KDO30910.1 - 0.042 14.1 1.2 0.094 13.0 0.7 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RE_BstXI PF09552.10 KDO30910.1 - 0.062 12.5 0.8 0.11 11.7 0.8 1.3 1 0 0 1 1 1 0 BstXI restriction endonuclease Golgin_A5 PF09787.9 KDO30910.1 - 0.11 11.9 12.9 0.23 10.9 12.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 KDO30910.1 - 0.24 10.9 6.8 0.38 10.3 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Elicitin PF00964.17 KDO30911.1 - 1e-13 51.1 5.1 7.1e-08 32.5 0.2 2.1 2 0 0 2 2 2 2 Elicitin Elicitin PF00964.17 KDO30912.1 - 5.5e-14 52.0 1.5 5.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Elicitin Elicitin PF00964.17 KDO30913.1 - 2.1e-05 24.5 0.2 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 Elicitin PX PF00787.24 KDO30914.1 - 8.8e-18 64.3 0.1 1.1e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 PX domain HlyE PF06109.13 KDO30915.1 - 4.4e-08 32.8 1.7 5.6e-08 32.5 1.7 1.1 1 0 0 1 1 1 1 Haemolysin E (HlyE) CwsA PF10814.8 KDO30915.1 - 0.0056 16.8 1.3 0.0099 16.0 1.3 1.4 1 0 0 1 1 1 1 Cell wall synthesis protein CwsA NPV_P10 PF05531.12 KDO30915.1 - 0.015 15.8 1.5 0.88 10.1 0.4 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KDO30915.1 - 0.068 13.3 1.7 0.36 11.0 0.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Acetyltransf_16 PF05301.11 KDO30915.1 - 0.12 12.2 0.5 0.27 11.0 0.5 1.6 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 HECT PF00632.25 KDO30916.1 - 4.6e-65 220.1 0.0 7.1e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TMEM71 PF15121.6 KDO30916.1 - 0.098 12.3 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 TMEM71 protein family DZR PF12773.7 KDO30916.1 - 0.4 10.7 2.1 0.88 9.6 2.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.8 KDO30916.1 - 9.9 6.1 7.6 2.3 8.2 1.2 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Sec63 PF02889.16 KDO30917.1 - 2e-44 151.7 0.1 2.8e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KDO30917.1 - 1.1e-19 70.3 0.0 2.6e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4589 PF15252.6 KDO30918.1 - 0.21 11.5 1.7 0.49 10.4 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) zf-BED PF02892.15 KDO30918.1 - 1.5 8.9 5.0 5.9 7.0 5.0 2.1 1 1 0 1 1 1 0 BED zinc finger Spt20 PF12090.8 KDO30919.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Spt20 family Actin PF00022.19 KDO30920.1 - 6e-96 321.5 0.0 2.8e-94 316.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KDO30920.1 - 0.032 13.0 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein HECT PF00632.25 KDO30923.1 - 9.3e-75 251.9 0.0 1.2e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO30923.1 - 1.6e-06 27.3 1.1 2.9e-06 26.5 1.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1974 PF09317.11 KDO30924.1 - 5e-57 193.6 0.6 2.6e-56 191.3 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 KDO30924.1 - 9.9e-18 64.9 0.0 2.4e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KDO30924.1 - 2.1e-08 34.3 0.0 5.4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KDO30924.1 - 2.4e-08 34.3 0.3 5.3e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ABC_membrane PF00664.23 KDO30925.1 - 2e-38 132.6 29.3 5.9e-22 78.6 2.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO30925.1 - 1.4e-31 109.9 0.0 6.9e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO30925.1 - 0.0038 17.1 0.6 0.34 10.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO30925.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KDO30925.1 - 0.049 14.0 0.1 0.049 14.0 0.1 2.3 3 0 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 KDO30925.1 - 0.21 10.7 0.9 0.44 9.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CPT PF07931.12 KDO30925.1 - 0.58 10.0 2.7 17 5.2 0.3 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Yos1 PF08571.10 KDO30925.1 - 2.5 8.4 6.6 10 6.5 6.6 2.0 1 1 0 1 1 1 0 Yos1-like His_Phos_1 PF00300.22 KDO30926.1 - 9.2e-18 64.6 0.2 5.3e-17 62.2 0.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PH PF00169.29 KDO30926.1 - 4.9e-08 33.4 0.0 3.5e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 PH domain SNase PF00565.17 KDO30927.1 - 3.6e-23 82.1 0.2 5.3e-23 81.6 0.2 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PAN_1 PF00024.26 KDO30928.1 - 4.2e-11 42.7 4.1 0.042 13.8 0.0 5.1 4 1 1 5 5 5 3 PAN domain PIG-L PF02585.17 KDO30928.1 - 1.3e-09 38.7 1.2 3.9e-09 37.2 1.2 1.8 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_4 PF14295.6 KDO30928.1 - 2.3e-07 30.6 10.7 0.0038 17.1 0.1 3.6 3 0 0 3 3 3 3 PAN domain DUF1375 PF07119.12 KDO30928.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) GSCFA PF08885.11 KDO30928.1 - 0.15 11.7 0.3 0.27 10.8 0.3 1.3 1 0 0 1 1 1 0 GSCFA family ABC_membrane PF00664.23 KDO30929.1 - 2.6e-53 181.4 36.8 1.6e-27 96.8 19.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO30929.1 - 7.1e-50 169.1 0.0 5.6e-28 98.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO30929.1 - 2.8e-07 30.2 1.7 0.033 13.6 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO30929.1 - 2.1e-06 27.7 0.2 0.033 14.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KDO30929.1 - 6.8e-06 26.1 0.4 0.011 15.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO30929.1 - 2.8e-05 24.6 0.2 0.028 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO30929.1 - 0.00049 19.8 0.3 1 9.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO30929.1 - 0.0011 18.9 1.4 0.38 10.5 0.1 3.4 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO30929.1 - 0.0014 18.9 1.1 1.7 8.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KDO30929.1 - 0.0056 15.9 1.0 0.65 9.1 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KDO30929.1 - 0.012 16.0 0.1 2.7 8.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KDO30929.1 - 0.027 15.0 0.1 0.58 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KDO30929.1 - 0.037 13.7 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KDO30929.1 - 0.04 13.7 0.8 13 5.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 KDO30929.1 - 0.046 13.2 0.6 6.9 6.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KDO30929.1 - 0.057 13.0 0.9 1.7 8.2 0.1 2.7 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KDO30929.1 - 0.066 13.4 1.2 2.6 8.3 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KDO30929.1 - 0.13 12.7 0.1 5 7.6 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO30929.1 - 0.22 12.1 0.0 22 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KDO30929.1 - 0.22 11.5 0.9 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KDO30929.1 - 0.24 11.4 3.9 6.8 6.7 0.4 2.4 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KDO30929.1 - 0.25 11.0 3.1 9.4 5.9 1.0 3.0 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO30929.1 - 0.34 10.2 0.8 10 5.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KDO30929.1 - 0.46 10.5 2.0 0.71 9.9 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 KDO30929.1 - 1.2 9.0 3.5 12 5.8 0.1 3.0 2 1 0 2 2 2 0 NACHT domain SAP PF02037.27 KDO30931.1 - 8.6e-11 41.3 0.7 1.8e-10 40.3 0.7 1.6 1 0 0 1 1 1 1 SAP domain INCENP_ARK-bind PF03941.15 KDO30931.1 - 9.7e-11 41.5 0.4 9.7e-11 41.5 0.4 3.1 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region HeH PF12949.7 KDO30931.1 - 0.036 13.8 1.3 0.062 13.0 0.1 2.1 2 0 0 2 2 2 0 HeH/LEM domain Peptidase_C58 PF03543.14 KDO30931.1 - 0.86 9.3 3.5 1.3 8.7 2.8 1.6 1 1 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen LMBR1 PF04791.16 KDO30931.1 - 2.9 6.7 4.5 4.5 6.1 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Acetyltransf_10 PF13673.7 KDO30932.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO30932.1 - 0.052 13.8 0.1 0.11 12.7 0.1 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family RNA_pol_I_TF PF04090.12 KDO30933.1 - 0.067 12.7 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor NMO PF03060.15 KDO30936.1 - 0.042 13.2 0.1 0.051 12.9 0.1 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Methyltr_RsmB-F PF01189.17 KDO30939.1 - 2.8e-10 40.2 0.1 7.3e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Histone PF00125.24 KDO30940.1 - 1.3e-19 70.9 0.0 1.6e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KDO30940.1 - 5.1e-11 42.1 0.2 1.1e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KDO30940.1 - 0.00025 21.3 0.3 0.00035 20.8 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CesT PF05932.13 KDO30941.1 - 0.1 12.8 0.6 0.17 12.0 0.6 1.3 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family WD40 PF00400.32 KDO30942.1 - 9.7e-29 99.0 23.6 1.2e-06 29.1 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30942.1 - 1.4e-16 60.6 1.0 0.029 14.7 0.0 6.2 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KDO30942.1 - 8.2e-09 35.5 0.1 1.8e-08 34.4 0.1 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KDO30942.1 - 0.0023 16.9 0.4 0.53 9.2 0.0 3.1 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO30942.1 - 0.0081 16.1 0.4 0.74 9.7 0.0 3.3 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KDO30942.1 - 0.052 12.2 0.2 0.83 8.2 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KDO30942.1 - 0.068 13.1 0.3 90 3.2 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KDO30942.1 - 1.3 6.9 2.9 11 3.8 0.1 2.5 2 1 1 3 3 3 0 IKI3 family Hira PF07569.11 KDO30943.1 - 3.4e-20 72.7 0.3 4.5e-20 72.3 0.3 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split DUF4708 PF15813.5 KDO30944.1 - 5.2e-06 25.8 0.0 1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4708) DUF4471 PF14740.6 KDO30945.1 - 6.3e-83 278.5 0.2 8.1e-83 278.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 KDO30945.1 - 3.2e-21 75.4 0.1 9e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) PRT_C PF08372.10 KDO30945.1 - 0.025 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal GTP_cyclohydro2 PF00925.20 KDO30945.1 - 0.046 13.3 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II FliX PF10768.9 KDO30945.1 - 0.059 13.9 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator RhoGAP PF00620.27 KDO30946.1 - 1e-21 77.4 0.0 2.1e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.28 KDO30946.1 - 0.00086 19.6 0.0 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain RWP-RK PF02042.15 KDO30947.1 - 9.1e-17 60.8 0.1 1.6e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain SMG1_N PF17229.2 KDO30947.1 - 0.055 14.2 0.2 0.14 12.9 0.2 1.6 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal Fez1 PF06818.15 KDO30948.1 - 0.0019 18.7 21.9 0.04 14.4 2.6 2.3 1 1 1 2 2 2 1 Fez1 APC_N_CC PF16689.5 KDO30948.1 - 0.0066 16.5 3.9 0.022 14.8 0.6 3.1 2 0 0 2 2 2 1 Coiled-coil N-terminus of APC, dimerisation domain YlmH_RBD PF17774.1 KDO30948.1 - 0.016 15.5 0.7 21 5.5 0.1 3.5 3 0 0 3 3 3 0 Putative RNA-binding domain in YlmH HALZ PF02183.18 KDO30948.1 - 0.018 15.2 6.0 0.12 12.7 0.4 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF2935 PF11155.8 KDO30948.1 - 0.02 15.2 0.6 2.6 8.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Nucleoporin_FG2 PF15967.5 KDO30948.1 - 0.11 11.0 0.8 0.17 10.4 0.8 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF3140 PF11338.8 KDO30948.1 - 0.13 12.7 0.4 0.13 12.7 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3140) GAS PF13851.6 KDO30948.1 - 0.33 10.3 32.3 0.018 14.4 6.8 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2151 PF10221.9 KDO30948.1 - 1.3 7.5 13.2 1.8 7.0 13.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Phage_int_SAM_2 PF12834.7 KDO30948.1 - 3.9 8.2 6.9 4.5 8.0 0.3 3.0 3 0 0 3 3 3 0 Phage integrase, N-terminal TPR_MLP1_2 PF07926.12 KDO30948.1 - 7.9 6.6 29.6 11 6.1 0.1 4.3 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Abhydrolase_2 PF02230.16 KDO30949.1 - 3.6e-49 167.5 0.0 4.1e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KDO30949.1 - 1.4e-08 34.5 0.2 1.3e-06 28.1 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 KDO30949.1 - 1.7e-06 27.7 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KDO30949.1 - 2e-06 27.3 0.1 0.014 14.7 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO30949.1 - 3.7e-05 24.4 4.0 0.00018 22.2 4.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KDO30949.1 - 0.0004 20.1 0.0 0.00063 19.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KDO30949.1 - 0.00094 19.1 0.1 0.46 10.3 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KDO30949.1 - 0.003 17.3 0.0 2.7 7.6 0.1 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold Cutinase PF01083.22 KDO30949.1 - 0.043 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Tcp10_C PF07202.13 KDO30951.1 - 0.0047 16.9 0.3 0.34 10.9 0.0 2.7 2 1 0 2 2 2 1 T-complex protein 10 C-terminus Nop25 PF09805.9 KDO30951.1 - 0.15 12.5 6.1 0.26 11.7 6.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Cwf_Cwc_15 PF04889.12 KDO30951.1 - 3 7.5 16.2 5.2 6.7 16.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2272 PF10030.9 KDO30953.1 - 0.098 12.4 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) Peptidase_C97 PF05903.14 KDO30954.1 - 3.3e-33 114.6 0.0 4.2e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 KDO30954.1 - 0.0093 16.3 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF778) AMP-binding PF00501.28 KDO30955.1 - 0.00017 20.4 0.1 0.0002 20.1 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GGACT PF06094.12 KDO30956.1 - 2.5e-25 89.4 0.2 2.8e-25 89.3 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Evr1_Alr PF04777.13 KDO30957.1 - 0.067 13.7 0.3 0.78 10.2 0.0 2.2 1 1 1 2 2 2 0 Erv1 / Alr family p450 PF00067.22 KDO30958.1 - 3.9e-63 213.8 0.0 4.8e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dynein_C PF18199.1 KDO30959.1 - 9.2e-102 340.4 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KDO30959.1 - 8.4e-22 77.7 0.0 1.4e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_6 PF12774.7 KDO30960.1 - 3.3e-154 512.7 0.0 1.3e-152 507.4 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO30960.1 - 2e-133 445.4 9.0 2e-133 445.4 9.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO30960.1 - 1.6e-100 335.7 2.6 4.5e-100 334.3 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO30960.1 - 1.4e-82 276.1 2.8 1.2e-80 269.8 0.1 3.6 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO30960.1 - 1.8e-80 268.7 0.9 1.4e-76 256.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_heavy PF03028.15 KDO30960.1 - 9.1e-50 167.7 0.0 7.2e-45 151.9 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KDO30960.1 - 1.4e-37 129.6 8.0 2.9e-37 128.5 8.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KDO30960.1 - 4.4e-29 101.2 0.1 1.8e-28 99.2 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KDO30960.1 - 1.4e-20 73.7 0.0 3.2e-05 23.9 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KDO30960.1 - 3.8e-15 55.9 0.5 2.5e-14 53.3 0.1 2.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 KDO30960.1 - 1.5e-06 28.5 4.5 0.081 13.2 0.0 5.3 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 KDO30960.1 - 1.1e-05 25.8 2.5 0.68 10.4 0.0 4.4 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KDO30960.1 - 1.7e-05 24.1 0.0 0.0077 15.3 0.0 3.9 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_16 PF13191.6 KDO30960.1 - 2e-05 25.1 0.9 0.45 10.9 0.0 4.6 4 1 0 4 4 3 2 AAA ATPase domain DUF853 PF05872.12 KDO30960.1 - 4e-05 22.4 2.2 0.25 9.9 0.0 3.3 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) RNA_helicase PF00910.22 KDO30960.1 - 4.5e-05 23.8 0.1 3.6 8.0 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 KDO30960.1 - 0.0021 17.8 0.5 4.1 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KDO30960.1 - 0.0067 17.0 0.0 0.1 13.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KDO30960.1 - 0.0094 14.9 0.7 0.57 9.0 0.0 3.2 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KDO30960.1 - 0.01 15.6 0.1 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO30960.1 - 0.014 14.8 0.1 2.3 7.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KDO30960.1 - 0.022 14.2 0.3 4.4 6.6 0.0 3.7 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KDO30960.1 - 0.029 14.7 0.8 10 6.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain YjcZ PF13990.6 KDO30960.1 - 0.03 13.7 0.3 0.077 12.4 0.3 1.6 1 0 0 1 1 1 0 YjcZ-like protein ABC_tran PF00005.27 KDO30960.1 - 0.07 13.6 0.2 10 6.6 0.0 3.3 2 0 0 2 2 2 0 ABC transporter Meiosis_expr PF15163.6 KDO30960.1 - 0.14 12.8 1.0 1.6 9.4 0.1 2.6 2 0 0 2 2 2 0 Meiosis-expressed DUF87 PF01935.17 KDO30960.1 - 0.18 11.9 12.3 0.62 10.1 0.0 4.4 5 0 0 5 5 3 0 Helicase HerA, central domain DUF4699 PF15770.5 KDO30960.1 - 0.23 11.2 1.5 0.48 10.2 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) ATPase PF06745.13 KDO30960.1 - 0.54 9.6 4.4 0.39 10.0 0.0 3.1 4 0 0 4 4 3 0 KaiC CSTF2_hinge PF14327.6 KDO30960.1 - 0.65 10.5 2.5 2.6 8.6 0.8 2.7 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Sigma54_activat PF00158.26 KDO30960.1 - 1.1 8.9 3.4 2.2 8.0 0.0 3.1 5 0 0 5 5 2 0 Sigma-54 interaction domain LOH1CR12 PF10158.9 KDO30960.1 - 2.9 7.9 9.5 3.4 7.7 0.1 4.7 4 0 0 4 4 3 0 Tumour suppressor protein NPV_P10 PF05531.12 KDO30960.1 - 3.6 8.1 14.9 4.6 7.8 0.1 5.3 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein NFRKB_winged PF14465.6 KDO30960.1 - 3.9 7.7 6.6 4.1 7.6 0.0 4.1 4 0 0 4 4 2 0 NFRKB Winged Helix-like DUF1664 PF07889.12 KDO30960.1 - 8 6.5 16.5 7 6.7 0.1 5.3 5 0 0 5 5 4 0 Protein of unknown function (DUF1664) Transket_pyr PF02779.24 KDO30961.1 - 1.8e-60 203.6 0.0 3.1e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KDO30961.1 - 4.4e-51 173.6 0.0 6.9e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KDO30961.1 - 2.7e-49 166.8 0.0 6.4e-49 165.6 0.0 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal FGGY_C PF02782.16 KDO30962.1 - 2e-21 76.7 4.8 2e-21 76.7 4.8 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KDO30962.1 - 1.8e-13 50.6 0.0 2.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Chitin_synth_1 PF01644.17 KDO30963.1 - 3.5e-43 147.4 0.0 5.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KDO30963.1 - 4.7e-27 94.8 0.2 1.2e-22 80.3 0.1 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KDO30963.1 - 3.4e-13 50.0 1.8 9.6e-13 48.5 1.8 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 MIT PF04212.18 KDO30963.1 - 8.2e-11 41.8 0.3 2.4e-10 40.3 0.3 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 KDO30963.1 - 6.3e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 KDO30963.1 - 8.2e-10 38.5 0.0 2.2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_transf_21 PF13506.6 KDO30963.1 - 0.014 14.9 0.0 6.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF2150 PF09920.9 KDO30963.1 - 0.22 11.5 1.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) RhoGEF PF00621.20 KDO30964.1 - 3.4e-61 206.7 0.0 1.4e-33 116.7 0.0 2.8 2 1 0 2 2 2 2 RhoGEF domain FYVE PF01363.21 KDO30964.1 - 6.5e-18 64.6 9.0 6.5e-18 64.6 9.0 1.9 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 KDO30964.1 - 5.3e-12 46.2 0.0 0.0024 18.4 0.0 3.8 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 KDO30964.1 - 0.012 16.0 0.6 30 5.1 0.0 4.3 4 1 0 4 4 4 0 Pleckstrin homology domain PH_13 PF16652.5 KDO30964.1 - 0.016 15.0 6.3 1.7 8.4 0.1 4.1 5 0 0 5 5 5 0 Pleckstrin homology domain PH_9 PF15410.6 KDO30964.1 - 0.023 15.1 0.5 30 5.0 0.0 3.9 4 0 0 4 4 4 0 Pleckstrin homology domain FtsK_gamma PF09397.10 KDO30964.1 - 0.15 11.9 0.3 9.2 6.2 0.0 3.3 3 0 0 3 3 3 0 Ftsk gamma domain FYVE_2 PF02318.16 KDO30964.1 - 1.9 8.7 9.6 0.18 12.0 3.9 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PH_8 PF15409.6 KDO30964.1 - 2 8.7 4.9 8.8 6.7 0.9 3.5 3 0 0 3 3 3 0 Pleckstrin homology domain Vir_act_alpha_C PF10400.9 KDO30964.1 - 2.2 9.1 7.9 0.42 11.3 2.4 2.9 3 1 0 3 3 3 0 Virulence activator alpha C-term fn3 PF00041.21 KDO30965.1 - 2.3e-86 284.2 63.9 9e-11 42.0 2.1 20.9 19 0 0 19 19 19 15 Fibronectin type III domain PA14 PF07691.12 KDO30965.1 - 3.8e-50 169.5 4.9 1.7e-26 92.8 0.1 4.7 5 0 0 5 5 5 2 PA14 domain Filamin PF00630.19 KDO30965.1 - 4.5e-48 162.3 0.0 3.1e-08 34.4 0.0 12.8 11 4 1 12 12 12 6 Filamin/ABP280 repeat Pur_ac_phosph_N PF16656.5 KDO30965.1 - 2.2e-13 50.6 57.8 1.3e-05 25.7 0.1 13.8 15 0 0 15 15 15 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KDO30965.1 - 5.4e-05 23.5 5.6 16 6.0 0.0 7.8 8 0 0 8 8 8 1 Uncharacterised conserved protein (DUF2369) GLEYA PF10528.9 KDO30965.1 - 0.00013 22.3 17.1 0.0057 17.1 0.1 7.3 8 0 0 8 8 8 2 GLEYA domain DUF4390 PF14334.6 KDO30965.1 - 0.023 14.1 0.0 11 5.5 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4390) FeS_assembly_P PF01883.19 KDO30965.1 - 0.025 14.7 1.5 11 6.3 0.0 5.1 4 0 0 4 4 4 0 Iron-sulfur cluster assembly protein POTRA_1 PF08478.10 KDO30965.1 - 0.038 14.3 0.2 7.8 6.9 0.0 5.0 7 0 0 7 7 7 0 POTRA domain, FtsQ-type DHHC PF01529.20 KDO30966.1 - 3.5e-29 101.6 15.0 3.5e-29 101.6 15.0 2.9 3 0 0 3 3 3 1 DHHC palmitoyltransferase MPC PF03650.13 KDO30966.1 - 0.12 12.5 0.4 0.25 11.5 0.4 1.6 1 1 0 1 1 1 0 Mitochondrial pyruvate carriers DUF4064 PF13273.6 KDO30966.1 - 1 9.7 0.0 1 9.7 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Peptidase_C48 PF02902.19 KDO30967.1 - 1.1e-13 51.6 0.0 2.1e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain OrfB_Zn_ribbon PF07282.11 KDO30968.1 - 0.0086 16.0 1.6 0.019 14.9 1.6 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS91 PF14319.6 KDO30968.1 - 0.076 13.1 0.7 0.2 11.7 0.7 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain YhfH PF14149.6 KDO30968.1 - 0.076 13.0 4.3 0.58 10.2 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein Zn_Tnp_IS1595 PF12760.7 KDO30968.1 - 0.14 12.2 4.5 0.9 9.6 4.3 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 KDO30968.1 - 0.14 12.2 1.2 0.31 11.1 1.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO30968.1 - 0.14 11.9 3.1 5.7 6.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain EF-1_beta_acid PF10587.9 KDO30968.1 - 0.16 12.4 0.0 0.16 12.4 0.0 3.6 3 0 0 3 3 2 0 Eukaryotic elongation factor 1 beta central acidic region zf-ribbon_3 PF13248.6 KDO30968.1 - 0.19 11.2 5.8 1.7 8.2 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 KDO30968.1 - 0.43 10.7 2.8 3 8.0 2.8 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_S27 PF01599.19 KDO30968.1 - 0.55 10.4 8.1 0.65 10.2 1.0 2.6 1 1 1 2 2 2 0 Ribosomal protein S27a RNA_POL_M_15KD PF02150.16 KDO30968.1 - 0.79 9.7 3.1 1.8 8.5 3.1 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 KDO30968.1 - 1.6 8.9 5.0 12 6.1 5.0 2.3 1 1 0 1 1 1 0 Zinc ribbon domain zf-tcix PF14952.6 KDO30968.1 - 5.4 6.7 6.3 16 5.2 0.6 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding UDPGP PF01704.18 KDO30969.1 - 6.9e-172 571.7 0.2 7.8e-172 571.6 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 KDO30969.1 - 0.031 13.1 0.5 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Exo_endo_phos PF03372.23 KDO30970.1 - 4.7e-10 39.4 0.1 9.7e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SCAB-Ig PF16709.5 KDO30970.1 - 0.0013 18.7 0.0 0.0035 17.4 0.0 1.7 1 1 0 1 1 1 1 Ig domain of plant-specific actin-binding protein HTH_Tnp_Tc5 PF03221.16 KDO30971.1 - 1.3e-13 50.8 0.0 4.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KDO30971.1 - 0.00027 20.5 0.1 0.00094 18.8 0.2 1.8 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KDO30971.1 - 0.00039 20.5 1.7 0.0015 18.6 0.4 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 KDO30971.1 - 0.00044 20.0 0.1 0.00099 18.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KDO30971.1 - 0.0016 18.7 0.7 0.01 16.1 0.1 2.1 1 1 1 2 2 2 1 Transposase BrkDBD PF09607.10 KDO30971.1 - 0.023 14.4 0.5 0.063 13.1 0.1 1.9 1 1 1 2 2 2 0 Brinker DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KDO30971.1 - 0.029 13.8 0.2 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 KDO30971.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 HTH DNA binding domain UPF0122 PF04297.14 KDO30971.1 - 0.053 13.8 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4_2 PF08281.12 KDO30971.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_tail_APC PF16778.5 KDO30971.1 - 0.095 12.6 1.1 0.17 11.8 1.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein tRNA_m1G_MT PF01746.21 KDO30972.1 - 2.6e-11 43.6 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase zf-LYAR PF08790.11 KDO30972.1 - 0.11 12.4 0.8 0.24 11.3 0.8 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DUF3742 PF12553.8 KDO30972.1 - 0.12 12.5 3.6 0.37 10.9 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) Connexin PF00029.19 KDO30972.1 - 0.32 10.7 1.2 0.49 10.1 1.2 1.3 1 0 0 1 1 1 0 Connexin EMC3_TMCO1 PF01956.16 KDO30972.1 - 0.43 10.3 1.0 0.71 9.6 1.0 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Tmemb_185A PF10269.9 KDO30973.1 - 0.0026 17.5 23.7 0.01 15.5 13.5 2.8 1 1 0 2 2 2 2 Transmembrane Fragile-X-F protein efThoc1 PF11957.8 KDO30975.1 - 3.2e-89 299.9 0.0 4.7e-89 299.3 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DUF4083 PF13314.6 KDO30975.1 - 0.2 11.6 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Spindle_Spc25 PF08234.12 KDO30976.1 - 7.7e-21 74.1 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF724 PF05266.14 KDO30976.1 - 0.036 13.9 5.4 0.057 13.2 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4262 PF14081.6 KDO30976.1 - 0.11 12.7 0.2 0.32 11.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4262) KcnmB2_inactiv PF09303.10 KDO30976.1 - 0.19 11.6 1.0 0.82 9.5 0.0 2.5 3 0 0 3 3 3 0 KCNMB2, ball and chain domain TMPIT PF07851.13 KDO30976.1 - 0.46 9.7 2.5 0.6 9.3 2.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 KDO30976.1 - 1.1 9.5 9.4 1.8e+02 2.4 9.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 KDO30976.1 - 1.1 8.5 10.5 0.73 9.1 8.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KDO30976.1 - 1.8 9.1 13.5 0.78 10.3 10.6 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 KDO30977.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.6 KDO30977.1 - 6.2 6.8 13.8 12 5.8 13.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CTP_transf_like PF01467.26 KDO30978.1 - 5.7e-13 49.3 0.0 1.8e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Cytidylyltransferase-like Elicitin PF00964.17 KDO30979.1 - 1.2e-16 60.5 1.9 3e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 Elicitin Elicitin PF00964.17 KDO30980.1 - 2.8e-08 33.7 0.1 3.7e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Elicitin TruD PF01142.18 KDO30985.1 - 1.2e-67 228.6 0.0 4.3e-67 226.8 0.0 1.8 2 0 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) 3HCDH_RFF PF18321.1 KDO30985.1 - 0.009 16.4 2.3 0.035 14.6 0.2 3.0 2 0 0 2 2 2 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HA1 PF18239.1 KDO30985.1 - 0.091 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Hemagglutinin I GyrI-like PF06445.15 KDO30986.1 - 3.1e-13 50.3 0.0 3.9e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 KDO30986.1 - 2.7e-09 37.3 0.0 4.5e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Integron-associated effector binding protein BATS PF06968.13 KDO30987.1 - 2.2e-17 62.9 0.3 8.3e-17 61.1 0.1 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KDO30987.1 - 9.3e-14 52.1 0.5 1.8e-13 51.2 0.5 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Methyltr_RsmB-F PF01189.17 KDO30988.1 - 1.1e-34 119.8 0.0 1.1e-33 116.6 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KDO30988.1 - 0.0036 17.4 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase RCC1 PF00415.18 KDO30989.1 - 6.2e-29 100.4 24.0 2.5e-14 53.6 1.7 6.4 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO30989.1 - 1.4e-23 82.1 22.2 4e-08 32.8 0.6 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.11 KDO30989.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 GAD-like domain MVL PF12151.8 KDO30990.1 - 9.2e-09 35.0 8.2 1.5 8.7 0.1 6.9 6 0 0 6 6 6 4 Mannan-binding protein Tex_YqgF PF16921.5 KDO30990.1 - 0.054 13.9 0.3 12 6.3 0.0 2.9 3 0 0 3 3 3 0 Tex protein YqgF-like domain DUF1388 PF07142.12 KDO30990.1 - 0.2 11.6 10.3 5.2 7.1 1.7 3.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) Methyltransf_11 PF08241.12 KDO30991.1 - 1.2e-06 29.0 0.0 3.9e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO30991.1 - 1.6e-05 25.5 0.0 3.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO30991.1 - 0.0028 17.2 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KDO30991.1 - 0.015 16.0 0.0 0.28 12.0 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 KDO30991.1 - 0.049 13.6 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KDO30991.1 - 0.05 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NDUF_B12 PF08122.12 KDO30992.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family SWIB PF02201.18 KDO30993.1 - 2.7e-12 46.4 0.1 6e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain LCIB_C_CA PF18599.1 KDO30993.1 - 0.38 10.0 1.1 14 4.9 0.1 2.1 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases WD40 PF00400.32 KDO30994.1 - 3e-17 62.7 6.5 0.008 17.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO30994.1 - 9.4e-08 32.3 0.0 0.14 12.5 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO30994.1 - 3.5e-05 22.9 0.0 0.042 12.8 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TMEM208_SND2 PF05620.11 KDO30995.1 - 9.3 6.0 7.2 51 3.6 2.0 3.1 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 RCC1 PF00415.18 KDO30996.1 - 1.7e-97 319.9 14.0 5.2e-15 55.8 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO30996.1 - 1e-52 175.0 31.6 2.1e-10 40.1 0.1 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KDO30996.1 - 3.3e-18 65.9 1.0 5.1e-17 62.1 0.1 2.7 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KDO30996.1 - 0.0058 16.7 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch SUKH-3 PF14433.6 KDO30996.1 - 0.055 13.9 0.1 2.6 8.5 0.1 3.1 3 1 0 3 3 3 0 SUKH-3 immunity protein RHS_repeat PF05593.14 KDO30996.1 - 0.11 13.0 2.0 0.36 11.4 0.2 2.8 3 0 0 3 3 3 0 RHS Repeat ALAD PF00490.21 KDO30996.1 - 0.11 11.6 0.7 0.18 11.0 0.7 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase 2-oxoacid_dh PF00198.23 KDO30997.1 - 5.5e-81 271.4 0.1 7.6e-81 271.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KDO30997.1 - 1.4e-19 69.7 0.2 5.7e-19 67.7 0.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KDO30997.1 - 6.3e-10 39.2 0.0 1.9e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KDO30997.1 - 9.7e-06 25.3 0.5 0.0014 18.4 0.1 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KDO30997.1 - 0.0043 16.3 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Transket_pyr PF02779.24 KDO30998.1 - 6.4e-48 162.8 0.0 8.4e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KDO30998.1 - 1.2e-29 102.7 0.0 2.5e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KDO30998.1 - 0.087 13.1 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DENN PF02141.21 KDO30999.1 - 1.4e-30 106.7 0.5 8.7e-28 97.5 0.2 2.5 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 KDO30999.1 - 1e-07 32.6 0.1 3.6e-07 30.8 0.1 2.1 1 0 0 1 1 1 1 uDENN domain PDZ_6 PF17820.1 KDO30999.1 - 7.7e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain dDENN PF03455.19 KDO30999.1 - 0.0004 20.3 0.2 0.0011 19.0 0.2 1.7 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 KDO30999.1 - 0.0062 16.5 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis PDZ_2 PF13180.6 KDO30999.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KDO30999.1 - 0.12 12.8 0.0 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Tricorn_PDZ PF14685.6 KDO30999.1 - 0.2 11.6 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain PHD PF00628.29 KDO31000.1 - 2.5e-12 46.5 8.7 5e-12 45.5 8.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_11 PF17123.5 KDO31000.1 - 1.7 8.5 7.9 3.9 7.3 7.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger Ion_trans_2 PF07885.16 KDO31002.1 - 9.8e-12 44.7 4.6 2.5e-11 43.4 4.6 1.7 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 KDO31002.1 - 5.7e-11 42.5 0.0 1.9e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KDO31002.1 - 2.3e-10 40.1 17.4 7.1e-10 38.5 17.4 1.8 1 1 0 1 1 1 1 Ion transport protein IRK PF01007.20 KDO31002.1 - 0.058 13.2 0.4 0.17 11.7 0.4 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain zf-C2HC_2 PF13913.6 KDO31003.1 - 0.042 13.8 1.0 0.095 12.6 1.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KDO31003.1 - 2.7 8.6 7.2 0.25 11.9 0.7 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Tetraspanin PF00335.20 KDO31004.1 - 3.2e-10 40.1 1.3 3.4e-10 40.0 1.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KDO31004.1 - 0.0015 18.4 0.5 0.0015 18.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) WBP-1 PF11669.8 KDO31004.1 - 0.062 13.9 0.0 0.066 13.8 0.0 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3043 PF11241.8 KDO31004.1 - 0.071 13.1 0.1 0.075 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Phage_holin_3_6 PF07332.11 KDO31004.1 - 0.09 12.8 1.6 0.1 12.7 1.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_S28 PF05577.12 KDO31005.1 - 2.7e-81 273.6 0.0 3.6e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO31005.1 - 5.8e-09 35.1 0.0 9.1e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KDO31005.1 - 6.6e-06 25.6 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KDO31005.1 - 0.00035 19.9 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KDO31005.1 - 0.00063 19.5 0.1 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO31005.1 - 0.0052 16.3 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tetraspanin PF00335.20 KDO31006.1 - 5.8e-18 65.4 15.3 2e-17 63.7 15.3 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF373 PF04123.13 KDO31006.1 - 0.0017 17.9 2.8 0.0017 17.9 2.8 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF373) SCAMP PF04144.13 KDO31006.1 - 0.0033 17.8 5.6 0.0033 17.8 5.6 2.2 2 0 0 2 2 2 1 SCAMP family Claudin_2 PF13903.6 KDO31006.1 - 0.024 14.4 13.1 0.62 9.8 5.9 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF2981 PF11200.8 KDO31006.1 - 0.16 11.7 6.8 0.28 10.9 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) WBP-1 PF11669.8 KDO31006.1 - 0.17 12.5 0.2 0.17 12.5 0.2 2.2 2 1 0 2 2 2 0 WW domain-binding protein 1 ThrE PF06738.12 KDO31006.1 - 0.7 9.2 12.8 0.021 14.2 5.5 2.1 2 0 0 2 2 2 0 Putative threonine/serine exporter PalH PF08733.10 KDO31006.1 - 0.81 8.6 6.2 1.6 7.7 6.2 1.4 1 0 0 1 1 1 0 PalH/RIM21 DUF3043 PF11241.8 KDO31006.1 - 0.93 9.5 6.1 0.089 12.8 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF3810 PF12725.7 KDO31006.1 - 1.5 8.1 4.1 0.51 9.6 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF3185 PF11381.8 KDO31006.1 - 3.1 7.9 10.3 0.74 9.9 4.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Abhydrolase_9_N PF15420.6 KDO31006.1 - 4.2 7.3 7.9 0.41 10.6 2.2 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus ABC2_membrane_2 PF12679.7 KDO31006.1 - 5.8 6.1 12.2 0.3 10.3 5.7 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Phage_Gp23 PF10669.9 KDO31006.1 - 8.8 6.7 7.0 2.5 8.4 0.1 2.7 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) CBF PF03914.17 KDO31008.1 - 2.8e-23 82.8 0.2 2.8e-23 82.8 0.2 2.8 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.11 KDO31008.1 - 7.7e-22 77.6 0.1 2.8e-21 75.8 0.1 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein Ribosomal_S27e PF01667.17 KDO31008.1 - 0.086 12.6 0.2 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 TENA_THI-4 PF03070.16 KDO31008.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Astro_capsid_p PF12226.8 KDO31008.1 - 2.9 7.0 7.5 4.9 6.2 7.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-CCCH PF00642.24 KDO31009.1 - 0.0015 18.4 6.7 0.0031 17.4 6.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ubie_methyltran PF01209.18 KDO31009.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4570 PF15134.6 KDO31011.1 - 0.00012 22.0 2.3 0.00012 22.0 2.3 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4570) ATP-synt_B PF00430.18 KDO31011.1 - 0.015 15.3 4.0 0.015 15.3 4.0 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) ATG7_N PF16420.5 KDO31011.1 - 0.076 12.6 0.2 0.089 12.4 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Lipoprotein_7 PF01540.16 KDO31011.1 - 0.081 12.2 0.5 0.15 11.3 0.5 1.5 1 1 0 1 1 1 0 Adhesin lipoprotein Sulfotransfer_3 PF13469.6 KDO31011.1 - 0.087 13.2 6.5 0.57 10.5 6.5 2.0 1 1 0 1 1 1 0 Sulfotransferase family V-ATPase_C PF03223.15 KDO31011.1 - 0.2 11.0 5.3 3.1 7.1 0.4 2.0 2 0 0 2 2 2 0 V-ATPase subunit C ATP-synt_G PF04718.15 KDO31011.1 - 0.35 11.7 2.7 1.3 9.9 2.7 2.0 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit SDF PF00375.18 KDO31012.1 - 1.4e-63 215.3 38.6 1.2e-62 212.2 38.6 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO31013.1 - 1e-73 248.7 41.1 1.5e-72 244.8 41.1 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO31015.1 - 2.5e-44 151.9 26.9 2.8e-44 151.7 26.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family TMEM100 PF16311.5 KDO31015.1 - 0.085 12.5 0.5 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 DUF5409 PF17421.2 KDO31015.1 - 0.21 12.3 2.5 0.35 11.6 1.4 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5409) SDF PF00375.18 KDO31016.1 - 6.4e-69 232.8 40.6 2.4e-43 148.7 15.2 2.8 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family EVC2_like PF12297.8 KDO31016.1 - 0.87 8.2 1.8 1.5 7.4 1.8 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein UreF PF01730.16 KDO31016.1 - 1.2 9.8 5.5 15 6.2 0.2 3.0 2 0 0 2 2 2 0 UreF ABC2_membrane_3 PF12698.7 KDO31017.1 - 3.6e-56 190.8 14.4 7.5e-33 114.1 0.0 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KDO31017.1 - 4.2e-56 189.2 0.0 6.4e-27 94.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO31017.1 - 2.4e-21 76.9 0.7 3.6e-08 33.6 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO31017.1 - 6.9e-06 26.6 0.1 0.0066 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO31017.1 - 8.6e-06 25.8 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KDO31017.1 - 1.2e-05 24.9 0.1 0.41 10.0 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO31017.1 - 3.2e-05 24.5 0.6 0.0041 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane PF01061.24 KDO31017.1 - 5.9e-05 22.6 14.1 5.9e-05 22.6 14.1 4.1 5 0 0 5 5 5 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 KDO31017.1 - 9.9e-05 21.7 12.9 9.9e-05 21.7 12.9 2.7 3 0 0 3 3 3 1 ABC-2 family transporter protein DUF4162 PF13732.6 KDO31017.1 - 0.00056 20.6 0.1 5.9 7.7 0.0 3.8 4 0 0 4 4 4 2 Domain of unknown function (DUF4162) AAA_29 PF13555.6 KDO31017.1 - 0.00065 19.4 1.5 0.12 12.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KDO31017.1 - 0.00078 19.2 0.3 1.6 8.4 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KDO31017.1 - 0.011 16.0 0.4 7.3 6.9 0.1 3.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KDO31017.1 - 0.011 15.8 0.3 6.9 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 KDO31017.1 - 0.025 13.9 0.8 0.82 9.0 0.1 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KDO31017.1 - 0.027 14.2 0.1 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO31017.1 - 0.095 12.9 0.1 15 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KDO31017.1 - 0.12 12.6 0.0 4.2 7.7 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KDO31017.1 - 0.31 10.6 1.4 10 5.7 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SDF PF00375.18 KDO31018.1 - 2e-43 148.9 25.1 2.3e-43 148.7 25.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5409 PF17421.2 KDO31018.1 - 0.2 12.4 1.6 0.44 11.3 1.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5409) SDF PF00375.18 KDO31019.1 - 4.5e-71 239.9 33.3 1.4e-70 238.3 33.3 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KDO31020.1 - 8.8e-70 235.7 37.4 4.4e-69 233.4 37.4 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5409 PF17421.2 KDO31020.1 - 0.075 13.8 1.8 0.26 12.0 1.8 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5409) DUF2207 PF09972.9 KDO31020.1 - 0.5 9.1 3.5 9.5 4.9 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DDE_1 PF03184.19 KDO31021.1 - 3.7e-08 33.2 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KDO31023.1 - 1.9e-68 230.7 0.0 2.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31023.1 - 2.3e-39 135.3 0.0 2.8e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO31023.1 - 4.9e-05 22.8 0.0 0.0002 20.8 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO31023.1 - 0.00026 19.9 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO31023.1 - 0.00087 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO31023.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO31023.1 - 0.035 13.1 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KDO31023.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KDO31023.1 - 0.073 12.7 0.0 0.9 9.1 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KDO31023.1 - 0.085 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KDO31023.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.25 KDO31024.1 - 1.6e-40 138.6 0.2 2.2e-40 138.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO31024.1 - 2.1e-24 86.4 0.4 3e-24 85.9 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO31024.1 - 6.8e-08 32.6 0.1 1.1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KDO31024.1 - 0.01 15.7 0.3 0.015 15.2 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KDO31024.1 - 0.021 14.3 1.4 0.15 11.5 1.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO31024.1 - 0.06 13.2 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF4439 PF14530.6 KDO31025.1 - 0.015 16.0 1.9 0.023 15.4 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) PKcGMP_CC PF16808.5 KDO31025.1 - 0.016 15.1 0.1 0.061 13.2 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CdvA PF18822.1 KDO31025.1 - 0.017 15.0 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Phage_Mu_Gam PF07352.12 KDO31025.1 - 0.019 14.9 0.4 6 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein NPV_P10 PF05531.12 KDO31025.1 - 0.17 12.4 0.7 1.2 9.7 0.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Suf PF05843.14 KDO31026.1 - 2.2e-49 169.0 4.6 1.6e-47 163.0 0.3 3.7 2 1 2 4 4 4 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KDO31026.1 - 8.2e-06 25.2 0.6 0.43 9.6 0.0 3.9 2 1 0 4 4 4 2 NRDE-2, necessary for RNA interference HAT PF02184.16 KDO31026.1 - 0.021 14.8 1.4 0.25 11.4 0.1 3.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_15 PF13429.6 KDO31026.1 - 0.031 13.5 1.1 0.59 9.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31026.1 - 0.19 12.6 1.6 4.4 8.4 0.1 4.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KDO31026.1 - 0.45 10.5 2.8 7.2 6.6 0.2 3.3 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 CSN8_PSD8_EIF3K PF10075.9 KDO31027.1 - 1.7e-23 83.2 0.1 3.2e-23 82.3 0.1 1.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KDO31027.1 - 0.00041 19.8 0.3 0.00055 19.4 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family Folate_rec PF03024.14 KDO31028.1 - 8.2e-13 48.6 8.0 1.3e-12 47.9 8.0 1.3 1 0 0 1 1 1 1 Folate receptor family DUF4229 PF14012.6 KDO31028.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) HemY_N PF07219.13 KDO31028.1 - 0.098 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus C2 PF00168.30 KDO31029.1 - 3.6e-35 120.4 0.0 7.7e-16 58.3 0.0 4.2 4 1 0 4 4 4 3 C2 domain EF-hand_1 PF00036.32 KDO31029.1 - 1.2e-19 68.3 9.6 1.3e-06 27.5 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO31029.1 - 8.7e-19 67.8 10.1 6.4e-10 39.3 0.2 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO31029.1 - 9e-18 62.6 4.0 4.6e-05 23.0 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KDO31029.1 - 9.6e-10 38.2 13.1 2.8e-07 30.3 0.7 4.7 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO31029.1 - 1.2e-08 34.0 7.2 0.00012 21.4 0.1 4.7 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 KDO31029.1 - 0.0006 20.1 8.2 0.025 14.9 0.5 3.3 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO31029.1 - 0.0018 18.6 0.3 0.25 11.7 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KDO31029.1 - 0.019 14.9 0.8 3.2 7.8 0.1 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand MotA_activ PF09114.10 KDO31029.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Transcription factor MotA, activation domain GAF PF01590.26 KDO31030.1 - 1.1e-18 68.1 1.1 2.9e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KDO31030.1 - 1.8e-13 51.0 0.0 8.1e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KDO31030.1 - 1.4e-05 25.4 0.0 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 2 GAF domain Hpt PF01627.23 KDO31031.1 - 0.0056 16.9 2.6 0.0056 16.9 2.6 3.5 3 1 1 4 4 4 1 Hpt domain HsbA PF12296.8 KDO31031.1 - 0.27 11.7 15.7 4.7 7.7 0.1 5.0 5 1 0 5 5 5 0 Hydrophobic surface binding protein A NPV_P10 PF05531.12 KDO31031.1 - 0.3 11.6 4.0 3.8 8.1 0.7 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PKcGMP_CC PF16808.5 KDO31031.1 - 0.54 10.1 8.3 20 5.2 0.6 5.1 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Baculo_PEP_C PF04513.12 KDO31031.1 - 0.89 9.6 8.1 1.3 9.1 1.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KDO31031.1 - 3.2 8.2 6.9 8.2 6.9 0.1 4.7 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 KDO31031.1 - 6.9 6.4 20.5 0.1 12.4 3.7 3.6 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain UPF0203 PF05254.12 KDO31032.1 - 1.8e-13 50.5 0.8 2.4e-13 50.1 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KDO31032.1 - 0.012 16.0 1.4 0.045 14.1 1.4 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mvb12 PF09452.10 KDO31032.1 - 0.051 14.0 0.3 0.12 12.8 0.1 1.6 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 COX6B PF02297.17 KDO31032.1 - 0.11 12.8 1.9 0.16 12.2 1.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Elicitin PF00964.17 KDO31033.1 - 1.8e-07 31.1 0.1 3.1e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Elicitin Elicitin PF00964.17 KDO31034.1 - 1.1e-06 28.7 0.5 1.9e-06 27.9 0.5 1.5 1 0 0 1 1 1 1 Elicitin Ank_2 PF12796.7 KDO31035.1 - 1.5e-32 112.0 9.5 5.3e-09 36.5 0.1 7.2 4 3 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31035.1 - 1.1e-23 83.3 16.6 4.7e-07 30.2 0.3 9.6 7 2 3 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31035.1 - 2e-21 73.7 9.0 0.054 14.1 0.0 10.4 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KDO31035.1 - 4.8e-18 65.0 16.2 9.3e-05 22.6 0.1 8.4 9 0 0 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO31035.1 - 1e-16 60.5 13.8 4.2e-05 23.8 0.0 8.9 8 0 0 8 8 8 4 Ankyrin repeat Ion_trans PF00520.31 KDO31035.1 - 8.3e-06 25.2 15.1 1.6e-05 24.3 15.1 1.4 1 0 0 1 1 1 1 Ion transport protein Nsp1_C PF05064.13 KDO31035.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region FlaC_arch PF05377.11 KDO31035.1 - 0.24 11.8 0.1 0.56 10.6 0.1 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2937 PF11157.8 KDO31035.1 - 0.51 10.0 4.4 1.8 8.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Apolipoprotein PF01442.18 KDO31036.1 - 0.087 12.7 21.6 0.22 11.4 21.6 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1985 PF09331.11 KDO31036.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) DUF883 PF05957.13 KDO31036.1 - 3.2 8.4 21.0 0.33 11.6 5.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Acetyltransf_CG PF14542.6 KDO31037.1 - 5.2e-16 58.5 0.0 6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KDO31037.1 - 4e-05 23.8 0.0 4.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO31037.1 - 0.00057 19.8 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO31037.1 - 0.0025 18.2 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OEP PF02321.18 KDO31038.1 - 0.16 11.7 6.5 0.25 11.1 6.5 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein Fe_hyd_lg_C PF02906.14 KDO31038.1 - 0.23 11.1 0.4 19 4.8 0.1 2.1 1 1 1 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Ank_2 PF12796.7 KDO31039.1 - 1.5e-29 102.4 2.4 3.4e-09 37.2 0.0 5.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31039.1 - 3.7e-19 68.8 12.0 6.9e-12 45.6 0.3 5.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31039.1 - 1.8e-18 64.7 6.9 3.1e-05 24.0 0.0 8.8 8 1 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KDO31039.1 - 9.3e-17 60.9 4.8 1.1e-09 38.4 0.0 5.8 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO31039.1 - 7.5e-16 57.8 12.7 4.1e-05 23.8 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat BTB PF00651.31 KDO31039.1 - 5e-12 46.0 0.0 0.00017 21.8 0.0 3.0 2 0 0 2 2 2 2 BTB/POZ domain Mito_fiss_reg PF05308.11 KDO31039.1 - 1 9.4 6.7 1.9 8.5 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CENP-F_leu_zip PF10473.9 KDO31040.1 - 0.00031 20.8 19.3 0.19 11.8 8.3 3.4 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFP_35_N PF07334.13 KDO31040.1 - 0.0018 18.3 3.7 0.42 10.7 0.1 3.3 3 0 0 3 3 3 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Takusan PF04822.13 KDO31040.1 - 0.011 15.6 6.1 10 6.1 0.4 3.4 2 1 0 3 3 3 0 Takusan GAS PF13851.6 KDO31040.1 - 0.012 14.9 16.7 0.11 11.8 7.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 KDO31040.1 - 0.027 14.8 10.4 2.6 8.4 1.3 4.3 2 2 2 4 4 4 0 Tup N-terminal DUF4618 PF15397.6 KDO31040.1 - 0.041 13.3 10.6 0.16 11.4 4.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) CASP_C PF08172.12 KDO31040.1 - 0.045 13.1 10.0 0.13 11.6 4.7 2.2 2 0 0 2 2 2 0 CASP C terminal UPF0242 PF06785.11 KDO31040.1 - 0.055 13.6 10.9 0.02 15.0 5.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 KDO31040.1 - 0.069 12.7 13.1 0.17 11.4 5.1 2.5 1 1 1 2 2 2 0 Leucine zipper LOH1CR12 PF10158.9 KDO31040.1 - 0.12 12.4 4.7 1.7 8.7 1.1 2.3 1 1 1 2 2 2 0 Tumour suppressor protein DUF4156 PF13698.6 KDO31040.1 - 0.21 12.0 1.1 3.8 7.9 0.1 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4156) Golgin_A5 PF09787.9 KDO31040.1 - 0.22 10.9 19.4 0.83 9.1 7.4 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 Tho2 PF11262.8 KDO31040.1 - 0.63 9.2 6.1 1.5 7.9 2.5 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Cnn_1N PF07989.11 KDO31040.1 - 0.73 10.0 0.0 0.73 10.0 0.0 3.4 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 Phage_GP20 PF06810.11 KDO31040.1 - 0.77 9.6 11.1 0.15 11.9 2.7 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KDO31040.1 - 1.3 9.1 29.7 0.57 10.2 15.1 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 KDO31040.1 - 1.4 9.3 9.1 0.89 9.9 4.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spidroin_N PF16763.5 KDO31040.1 - 2.2 8.3 13.7 0.76 9.8 1.8 3.2 1 1 2 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term BshC PF10079.9 KDO31040.1 - 2.6 6.7 9.5 1.4 7.6 0.4 2.1 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC DUF922 PF06037.11 KDO31040.1 - 2.7 7.8 9.8 13 5.6 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Seryl_tRNA_N PF02403.22 KDO31040.1 - 3 8.1 16.6 1.1 9.5 5.5 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 KDO31040.1 - 3.9 8.2 7.7 3.8 8.2 0.5 3.1 1 1 1 2 2 2 0 Initiation control protein YabA AAA_13 PF13166.6 KDO31040.1 - 5.1 5.6 15.1 9.2 4.8 15.1 1.4 1 1 0 1 1 1 0 AAA domain ZapB PF06005.12 KDO31040.1 - 5.3 7.6 15.6 6.5 7.3 7.5 3.4 3 1 0 3 3 3 0 Cell division protein ZapB Bap31_Bap29_C PF18035.1 KDO31040.1 - 6.4 6.9 15.0 7.8 6.6 0.2 3.4 3 1 1 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain FapA PF03961.13 KDO31040.1 - 7.4 5.0 8.3 3.2 6.3 2.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CC2-LZ PF16516.5 KDO31040.1 - 10 6.6 15.0 3.5 8.0 3.6 3.3 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Lebercilin PF15619.6 KDO31041.1 - 0.0014 18.3 9.4 0.0023 17.6 8.9 1.5 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ApoLp-III PF07464.11 KDO31041.1 - 0.03 14.4 3.6 0.04 14.0 3.6 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ATG16 PF08614.11 KDO31041.1 - 0.04 14.1 15.4 0.92 9.7 15.4 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2087 PF09860.9 KDO31041.1 - 0.21 11.7 1.5 0.41 10.8 0.3 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) PKcGMP_CC PF16808.5 KDO31041.1 - 0.24 11.3 12.7 1.3 8.9 0.3 4.0 3 2 2 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Rho_Binding PF08912.11 KDO31041.1 - 0.81 10.6 8.3 0.74 10.7 0.6 2.5 2 1 1 3 3 3 0 Rho Binding DUF3584 PF12128.8 KDO31041.1 - 1.4 6.4 18.1 0.13 9.7 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 KDO31041.1 - 2.5 8.5 10.6 6.7 7.1 10.6 1.6 1 1 0 1 1 1 0 Fez1 FAM184 PF15665.5 KDO31041.1 - 3.8 7.2 12.8 69 3.1 12.8 2.1 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B BRE1 PF08647.11 KDO31041.1 - 4.7 7.3 11.6 0.78 9.9 2.2 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 KDO31041.1 - 4.8 7.3 18.7 1.1 9.3 5.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 KDO31042.1 - 0.0026 16.0 2.4 0.0027 16.0 2.4 1.1 1 0 0 1 1 1 1 HOOK protein TssC PF17541.2 KDO31042.1 - 0.084 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB TMCO5 PF14992.6 KDO31042.1 - 0.095 12.3 1.0 0.11 12.0 1.0 1.1 1 0 0 1 1 1 0 TMCO5 family DUF948 PF06103.11 KDO31042.1 - 0.14 12.4 0.9 0.25 11.6 0.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 KDO31042.1 - 0.48 9.8 6.7 0.71 9.2 6.7 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KDO31042.1 - 0.76 9.1 6.6 0.96 8.7 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KDO31042.1 - 1.8 8.6 6.5 2.5 8.2 6.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KDO31042.1 - 2.4 8.7 12.0 14 6.2 12.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Filament PF00038.21 KDO31043.1 - 0.00016 21.4 1.5 0.00018 21.2 1.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein V-SNARE PF05008.15 KDO31043.1 - 0.0058 17.0 2.1 0.013 15.9 1.9 1.7 1 1 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus NrsF PF06532.11 KDO31043.1 - 0.024 14.4 1.2 0.047 13.4 1.2 1.5 1 0 0 1 1 1 0 Negative regulator of sigma F PIG-P PF08510.12 KDO31043.1 - 0.025 14.5 0.5 0.037 14.0 0.5 1.4 1 1 0 1 1 1 0 PIG-P LRS4 PF10422.9 KDO31043.1 - 0.061 12.9 0.7 0.082 12.5 0.7 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF948 PF06103.11 KDO31043.1 - 0.084 13.1 0.4 0.084 13.1 0.4 2.4 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KDO31043.1 - 0.11 12.5 0.6 0.2 11.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PepSY_2 PF13670.6 KDO31043.1 - 0.17 11.9 5.7 0.16 12.0 3.8 2.0 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain RPA_interact_N PF14766.6 KDO31043.1 - 0.2 11.3 0.9 0.34 10.6 0.9 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal PvlArgDC PF01862.16 KDO31043.1 - 0.39 10.5 3.8 0.99 9.2 3.8 1.7 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Questin_oxidase PF14027.6 KDO31043.1 - 0.74 9.3 4.8 0.89 9.0 4.8 1.1 1 0 0 1 1 1 0 Questin oxidase-like Phage_holin_7_1 PF16081.5 KDO31043.1 - 1.1 9.5 9.4 0.18 12.0 0.5 2.2 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2205 PF10224.9 KDO31043.1 - 1.5 8.9 4.2 1.3 9.1 1.1 2.1 1 1 1 2 2 2 0 Short coiled-coil protein DUF4337 PF14235.6 KDO31043.1 - 1.6 8.8 7.6 3.5 7.7 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) FAD-SLDH PF12318.8 KDO31043.1 - 4.6 7.3 8.1 11 6.1 4.4 2.4 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PRT_C PF08372.10 KDO31044.1 - 0.091 12.5 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SHR-BD PF06650.12 KDO31045.1 - 9e-18 64.6 0.0 2.9e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_1 PF00036.32 KDO31045.1 - 1.2e-17 62.1 0.7 0.0016 17.8 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO31045.1 - 6.2e-16 58.6 3.4 5.3e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO31045.1 - 3.5e-15 54.5 1.9 0.052 13.5 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain VPS13_C PF16909.5 KDO31045.1 - 2.1e-13 50.5 0.3 1.5e-06 28.1 0.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal EF-hand_5 PF13202.6 KDO31045.1 - 6.6e-11 41.2 0.9 0.013 15.0 0.1 4.8 4 0 0 4 4 4 3 EF hand ATG_C PF09333.11 KDO31045.1 - 6.7e-07 29.6 0.0 2.7e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain EF-hand_8 PF13833.6 KDO31045.1 - 1.5e-05 24.7 6.7 0.03 14.1 0.0 4.2 3 1 1 4 4 4 2 EF-hand domain pair C2 PF00168.30 KDO31045.1 - 0.00016 21.9 0.1 0.00076 19.7 0.0 2.1 2 0 0 2 2 2 1 C2 domain SPARC_Ca_bdg PF10591.9 KDO31045.1 - 0.00098 19.4 2.6 0.081 13.2 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO31045.1 - 2.3 8.2 3.8 13 5.8 0.1 3.3 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand RRM_5 PF13893.6 KDO31046.1 - 1.1e-30 105.8 0.0 5e-17 61.7 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KDO31046.1 - 1.9e-24 85.3 0.0 1.1e-08 34.8 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KDO31046.1 - 6.6e-12 45.5 0.0 2.3e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KDO31046.1 - 3.6e-05 23.5 0.0 0.056 13.3 0.0 3.4 4 0 0 4 4 4 2 Occluded RNA-recognition motif DUF4106 PF13388.6 KDO31046.1 - 0.00035 19.9 0.7 0.00097 18.5 0.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4106) NqrM PF04400.13 KDO31046.1 - 0.037 13.8 0.1 0.037 13.8 0.1 1.8 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM SID PF11778.8 KDO31046.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Septation initiation CDP-OH_P_transf PF01066.21 KDO31047.1 - 5.5e-15 55.9 0.1 5.5e-15 55.9 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CorA PF01544.18 KDO31050.1 - 2.8e-09 36.7 12.8 7e-09 35.4 12.8 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2367 PF10164.9 KDO31051.1 - 4.7e-17 62.4 3.2 7.6e-17 61.7 3.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) JmjC PF02373.22 KDO31051.1 - 0.17 12.3 0.5 0.25 11.8 0.5 1.2 1 0 0 1 1 1 0 JmjC domain, hydroxylase TAF1_subA PF14929.6 KDO31053.1 - 7.4e-10 38.8 0.1 1.3e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A UPF0020 PF01170.18 KDO31054.1 - 6.1e-19 68.5 0.7 1.9e-17 63.6 0.7 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KDO31054.1 - 1.5e-05 25.6 0.0 4.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KDO31054.1 - 0.041 13.3 0.0 0.24 10.8 0.0 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa CorA PF01544.18 KDO31058.1 - 2e-08 33.9 14.7 1.5e-07 31.0 14.7 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-met PF12874.7 KDO31059.1 - 0.00074 19.8 0.3 0.0012 19.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KDO31059.1 - 0.037 14.3 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNB PF00773.19 KDO31060.1 - 1.1e-92 310.9 0.3 2.5e-92 309.7 0.0 1.7 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 KDO31060.1 - 4.7e-22 77.8 0.0 1.2e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 KDO31060.1 - 5.7e-15 55.0 0.3 1.1e-14 54.1 0.3 1.5 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KDO31060.1 - 3.2e-13 49.6 0.0 8.8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KDO31060.1 - 5.1e-07 29.8 0.0 8.4e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain AOX PF01786.17 KDO31061.1 - 6.9e-72 241.5 0.2 9.4e-47 159.4 0.0 2.1 1 1 1 2 2 2 2 Alternative oxidase COQ7 PF03232.13 KDO31061.1 - 0.0089 15.8 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 ENOD93 PF03386.14 KDO31063.1 - 8.7e-06 25.5 0.4 1.5e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 KDO31063.1 - 0.0016 18.6 0.1 0.0016 18.6 0.1 2.6 2 1 0 2 2 2 1 Hypoxia induced protein conserved region Sulf_transp PF04143.14 KDO31065.1 - 4.3e-33 115.2 30.9 7.7e-33 114.4 30.9 1.4 1 1 0 1 1 1 1 Sulphur transport Tail_VII PF17091.5 KDO31065.1 - 0.061 13.2 0.3 0.38 10.7 0.3 2.4 1 0 0 1 1 1 0 Inovirus G7P protein ABC_tran PF00005.27 KDO31066.1 - 4.8e-27 95.1 0.0 7.4e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KDO31066.1 - 4.4e-21 75.3 18.6 1.1e-10 41.4 7.7 3.1 1 1 1 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 KDO31066.1 - 8.8e-11 42.2 0.0 4.7e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO31066.1 - 4.3e-05 23.1 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO31066.1 - 6.5e-05 23.4 0.1 0.00026 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KDO31066.1 - 7.3e-05 22.4 0.2 0.00022 20.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KDO31066.1 - 0.00023 20.8 0.3 0.00075 19.2 0.3 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO31066.1 - 0.0017 18.9 0.0 0.0028 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KDO31066.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 KDO31066.1 - 0.0029 17.5 0.0 0.0082 16.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KDO31066.1 - 0.011 16.3 0.1 0.059 13.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KDO31066.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO31066.1 - 0.025 14.7 0.0 0.073 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KDO31066.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KDO31066.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KDO31066.1 - 0.059 12.4 0.2 0.52 9.3 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KDO31066.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KDO31066.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF5368 PF17336.2 KDO31066.1 - 0.14 12.3 5.4 0.18 12.0 4.1 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5368) AAA_30 PF13604.6 KDO31066.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO31066.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain GST_C_5 PF16865.5 KDO31067.1 - 2.1e-08 34.7 0.0 9.4e-07 29.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO31067.1 - 2.8e-05 24.0 0.2 7.2e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO31067.1 - 8.8e-05 22.8 0.0 0.00042 20.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO31067.1 - 0.0002 21.6 0.0 0.0025 18.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO31067.1 - 0.0055 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO31067.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO31067.1 - 0.043 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HIG_1_N PF04588.13 KDO31068.1 - 0.00046 20.3 0.1 0.00077 19.6 0.1 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Pyr_redox_dim PF02852.22 KDO31069.1 - 2.2e-15 56.9 0.2 2.5e-15 56.7 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain AOX PF01786.17 KDO31070.1 - 2.1e-75 253.0 0.3 2.3e-73 246.3 0.3 2.1 1 1 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 KDO31070.1 - 0.042 13.6 0.3 0.11 12.3 0.3 1.7 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 AOX PF01786.17 KDO31072.1 - 7.2e-90 300.3 0.0 8.7e-90 300.0 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 KDO31072.1 - 0.11 12.3 1.1 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Tau95 PF09734.9 KDO31073.1 - 2.5e-30 106.1 0.2 5.7e-30 105.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KDO31073.1 - 2.3e-13 50.4 1.7 8.4e-12 45.4 0.1 3.2 2 1 0 2 2 2 1 Tau95 Triple barrel domain TFIIA PF03153.13 KDO31073.1 - 0.011 15.7 6.9 0.017 15.1 6.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 KDO31073.1 - 1.3 8.3 20.2 2.5 7.3 20.2 1.5 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 KDO31073.1 - 2.5 7.4 15.2 0.29 10.5 10.7 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Methyltransf_16 PF10294.9 KDO31074.1 - 1.6e-10 41.0 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO31074.1 - 0.045 13.2 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO31074.1 - 0.085 13.5 0.0 0.18 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ABC1 PF03109.16 KDO31075.1 - 1.5e-25 89.7 0.0 2.9e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KDO31075.1 - 0.00062 19.8 0.5 0.0033 17.4 0.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1500 PF07389.12 KDO31075.1 - 0.012 15.7 0.1 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) RIO1 PF01163.22 KDO31075.1 - 0.029 14.0 0.1 0.94 9.0 0.0 2.9 2 1 0 3 3 3 0 RIO1 family Acetyltransf_2 PF00797.17 KDO31077.1 - 4.8e-44 151.0 0.0 1e-43 149.9 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase tRNA-synt_2c PF01411.19 KDO31078.1 - 7.4e-158 526.5 0.0 1e-157 526.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KDO31078.1 - 7.7e-12 45.1 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF963 PF06131.11 KDO31079.1 - 0.014 14.8 7.0 0.074 12.5 0.4 3.4 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ins_P5_2-kin PF06090.12 KDO31080.1 - 2e-69 234.6 0.0 2.3e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DNA_binding_1 PF01035.20 KDO31080.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Tub PF01167.18 KDO31081.1 - 1.5e-67 227.8 0.0 1.8e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 KDO31081.1 - 5.8e-06 26.5 1.0 5.8e-06 26.5 1.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KDO31081.1 - 0.0001 22.5 1.1 0.00023 21.4 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3527 PF12043.8 KDO31081.1 - 0.00073 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) RINGv PF12906.7 KDO31081.1 - 0.0072 16.4 0.4 0.015 15.4 0.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 KDO31081.1 - 0.0098 15.7 1.9 0.022 14.6 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO31081.1 - 0.058 13.5 0.8 0.13 12.4 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Vasohibin PF14822.6 KDO31082.1 - 0.094 11.9 0.1 0.099 11.8 0.1 1.1 1 0 0 1 1 1 0 Vasohibin Spc7 PF08317.11 KDO31083.1 - 0.0042 16.0 2.5 0.0048 15.8 2.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 KDO31083.1 - 0.0079 16.4 4.5 0.01 16.1 4.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) NYD-SP28 PF14772.6 KDO31083.1 - 0.014 15.4 3.0 0.064 13.3 3.0 1.9 1 1 0 1 1 1 0 Sperm tail Acyl-CoA_dh_2 PF08028.11 KDO31083.1 - 0.015 15.6 1.4 0.019 15.2 1.4 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Lebercilin PF15619.6 KDO31083.1 - 0.055 13.1 5.8 0.19 11.4 4.0 1.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 KDO31083.1 - 0.11 12.3 5.2 0.52 10.0 5.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) ZapB PF06005.12 KDO31083.1 - 0.14 12.6 6.5 0.3 11.6 6.5 1.5 1 1 0 1 1 1 0 Cell division protein ZapB OmpH PF03938.14 KDO31083.1 - 0.27 11.5 5.8 0.76 10.1 5.8 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YabA PF06156.13 KDO31083.1 - 0.4 11.4 2.9 0.83 10.3 2.9 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KDO31083.1 - 1.9 8.3 7.6 0.34 10.7 0.6 2.3 1 1 1 2 2 2 0 Septum formation initiator HSF_DNA-bind PF00447.17 KDO31084.1 - 1.1e-26 93.3 2.3 2.3e-26 92.2 2.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding SMN PF06003.12 KDO31085.1 - 0.4 9.9 2.9 0.59 9.3 2.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-TAZ PF02135.16 KDO31086.1 - 2.2e-10 40.9 12.3 2.8e-10 40.5 12.3 1.1 1 0 0 1 1 1 1 TAZ zinc finger Ras PF00071.22 KDO31088.1 - 9e-21 74.1 0.0 2.2e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KDO31088.1 - 2.9e-16 59.8 0.0 6e-16 58.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO31088.1 - 0.00026 20.5 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO31088.1 - 0.047 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase 4HBT_2 PF13279.6 KDO31089.1 - 5e-16 59.3 0.1 6.7e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KDO31089.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-ACP thioesterase 4HBT PF03061.22 KDO31089.1 - 0.046 14.1 0.0 0.072 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily DUF1736 PF08409.11 KDO31090.1 - 0.049 13.6 0.9 0.16 11.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1736) DUF5602 PF18197.1 KDO31092.1 - 0.24 11.9 1.3 0.7 10.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5602) Se-cys_synth_N PF12390.8 KDO31094.1 - 0.041 14.1 0.4 0.31 11.3 0.4 2.7 1 0 0 1 1 1 0 Selenocysteine synthase N terminal DUF3591 PF12157.8 KDO31095.1 - 6.7e-91 305.2 0.0 1e-90 304.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KDO31095.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Ammonium_transp PF00909.21 KDO31096.1 - 5.6e-118 394.1 34.0 7e-118 393.8 34.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family zf_Rg PF17915.1 KDO31098.1 - 0.027 13.9 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Reverse gyrase zinc finger Retrotran_gag_2 PF14223.6 KDO31100.1 - 0.099 12.3 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2587 PF10759.9 KDO31101.1 - 0.026 14.0 0.2 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) GRDP-like PF07173.12 KDO31102.1 - 2.2e-14 54.3 0.0 3e-13 50.6 0.0 2.5 2 1 1 3 3 3 1 Glycine-rich domain-containing protein-like Elf1 PF05129.13 KDO31102.1 - 0.0055 16.7 0.3 0.013 15.5 0.2 1.6 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.6 KDO31102.1 - 0.15 11.8 0.7 0.35 10.6 0.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain DiS_P_DiS PF06750.13 KDO31102.1 - 0.18 11.9 0.7 0.45 10.7 0.7 1.6 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Cys_rich_CPXG PF14255.6 KDO31102.1 - 0.49 10.3 3.4 1.8 8.6 1.3 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG DZR PF12773.7 KDO31102.1 - 0.58 10.2 3.9 0.16 12.0 0.6 1.8 2 0 0 2 2 2 0 Double zinc ribbon Ank_2 PF12796.7 KDO31103.1 - 1.5e-70 233.8 17.3 3.3e-15 56.4 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31103.1 - 2.6e-54 174.8 23.2 0.0004 20.6 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank PF00023.30 KDO31103.1 - 2.5e-51 169.9 48.4 7.2e-05 23.1 0.1 12.1 11 1 1 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 KDO31103.1 - 8.5e-49 163.0 38.8 3.1e-08 33.7 0.2 12.0 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO31103.1 - 3.4e-48 161.4 17.0 1.5e-08 35.0 0.1 8.0 5 2 3 8 8 8 8 Ankyrin repeats (many copies) PEGA PF08308.11 KDO31103.1 - 0.62 10.0 2.1 12 5.9 0.0 3.9 5 0 0 5 5 5 0 PEGA domain Ank_2 PF12796.7 KDO31104.1 - 1.6e-12 47.9 0.3 1.7e-10 41.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31104.1 - 3.3e-07 30.1 0.2 0.049 14.2 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO31104.1 - 6.3e-07 29.6 1.8 0.024 15.1 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KDO31104.1 - 4.8e-05 23.8 0.0 0.0049 17.4 0.0 2.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31104.1 - 0.0048 17.2 0.3 0.21 11.9 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31105.1 - 1.6e-45 153.6 10.0 6.1e-10 39.6 0.0 7.9 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31105.1 - 1.4e-32 111.6 6.9 8.9e-08 32.5 0.0 8.8 7 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31105.1 - 1.2e-26 92.4 15.2 4.6e-06 26.8 0.0 9.2 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31105.1 - 3.4e-26 88.4 12.9 0.0093 16.4 0.0 12.0 12 0 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 KDO31105.1 - 1.1e-24 85.8 16.1 7.2e-06 26.2 0.0 11.4 12 0 0 12 12 12 5 Ankyrin repeat NCD3G PF07562.14 KDO31105.1 - 0.11 12.4 0.6 0.23 11.5 0.6 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR BTB_2 PF02214.22 KDO31106.1 - 3.1e-11 43.5 0.0 9e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain FUSC PF04632.12 KDO31106.1 - 0.027 13.0 9.9 0.039 12.5 9.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG17 PF04108.12 KDO31106.1 - 0.043 12.9 3.5 0.061 12.4 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 AIP3 PF03915.13 KDO31106.1 - 0.046 12.8 1.6 0.061 12.4 1.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DarA_N PF18788.1 KDO31106.1 - 0.097 12.8 0.3 1.6 8.8 0.0 2.4 2 1 0 2 2 2 0 Defence against restriction A N-terminal Golgin_A5 PF09787.9 KDO31106.1 - 0.12 11.8 2.4 0.16 11.4 2.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Het-C PF07217.11 KDO31106.1 - 0.16 10.5 0.5 0.22 10.0 0.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Baculo_PEP_C PF04513.12 KDO31106.1 - 0.24 11.5 2.3 0.36 10.9 1.6 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 KDO31106.1 - 1.3 9.4 3.2 1.6 9.0 0.7 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain CytochromB561_N PF09786.9 KDO31107.1 - 1.7e-31 109.9 0.0 3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome B561, N terminal Ank_2 PF12796.7 KDO31108.1 - 6.4e-07 29.9 0.0 0.00097 19.7 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31108.1 - 5.5e-06 26.3 0.1 0.0096 16.4 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KDO31108.1 - 0.017 15.7 0.1 0.12 13.0 0.0 2.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 KDO31108.1 - 0.021 15.3 0.3 0.37 11.3 0.3 2.6 2 1 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KDO31109.1 - 4.8e-85 280.2 37.0 2.1e-18 66.7 0.8 7.0 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31109.1 - 1e-60 201.4 16.6 8.1e-10 39.0 0.1 11.0 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KDO31109.1 - 3.9e-58 191.5 45.0 1.7e-07 31.3 0.1 13.4 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.6 KDO31109.1 - 2e-56 181.3 15.6 0.0001 22.5 0.0 13.8 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 KDO31109.1 - 3.5e-55 183.4 28.7 1.8e-08 34.4 0.2 10.9 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KDO31109.1 - 3e-36 125.0 0.0 5.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31109.1 - 4.8e-35 121.2 0.0 7.9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO31109.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KDO31110.1 - 1.2e-36 126.3 0.0 2.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31110.1 - 9.3e-36 123.5 0.0 2.8e-35 122.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 KDO31110.1 - 2.2e-34 117.9 13.6 5.6e-14 52.5 0.4 5.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31110.1 - 8.7e-32 109.1 8.6 1.3e-08 35.2 0.2 6.5 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO31110.1 - 1e-26 92.2 27.2 1.1e-06 28.9 1.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KDO31110.1 - 1.1e-25 89.3 19.7 1.6e-07 31.5 0.4 7.8 5 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31110.1 - 4.8e-24 81.8 8.8 0.046 14.3 0.1 9.3 10 0 0 10 10 10 6 Ankyrin repeat Kdo PF06293.14 KDO31110.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 KDO31111.1 - 2.3e-64 214.0 15.1 4.9e-13 49.5 0.2 6.6 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31111.1 - 1.4e-50 169.0 19.7 3.8e-11 43.3 0.0 9.4 6 3 3 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31111.1 - 2.9e-42 142.2 37.8 1.2e-06 28.7 0.3 12.3 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KDO31111.1 - 1.2e-40 136.3 39.3 7.7e-06 26.1 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 KDO31111.1 - 1.8e-35 116.9 26.5 0.00069 19.9 0.1 13.2 14 0 0 14 14 14 9 Ankyrin repeat Pkinase_Tyr PF07714.17 KDO31111.1 - 8.4e-29 100.6 0.0 1.6e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31111.1 - 1.2e-28 100.2 0.0 4e-28 98.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO31111.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 KDO31112.1 - 0.00015 21.9 0.1 0.00093 19.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31112.1 - 0.00069 20.2 0.3 0.0011 19.5 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31112.1 - 0.0019 18.7 0.1 0.0074 16.9 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO31112.1 - 0.0041 17.5 2.0 0.0046 17.3 0.1 2.0 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KDO31112.1 - 0.0046 17.3 0.1 0.033 14.7 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat Rab3-GTPase_cat PF13890.6 KDO31113.1 - 5e-50 169.3 0.5 5e-50 169.3 0.5 1.7 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit DUF1804 PF08822.11 KDO31113.1 - 0.21 11.6 1.5 7.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF4168 PF13767.6 KDO31114.1 - 0.23 12.7 7.8 0.97 10.7 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) FYVE PF01363.21 KDO31115.1 - 4.6e-13 49.1 13.0 5.8e-13 48.8 13.0 1.1 1 0 0 1 1 1 1 FYVE zinc finger COMM_domain PF07258.14 KDO31116.1 - 5.8e-09 35.9 0.0 9.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 COMM domain 2OG-FeII_Oxy_3 PF13640.6 KDO31117.1 - 1.6e-08 35.4 0.0 2.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 KDO31117.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Choline_transpo PF04515.12 KDO31118.1 - 1.2e-75 254.8 28.2 1.2e-75 254.8 28.2 2.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter Sel1 PF08238.12 KDO31119.1 - 3.1e-12 46.7 8.2 7.5e-06 26.5 0.2 3.7 3 1 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.6 KDO31119.1 - 0.21 12.2 5.2 5.4 7.7 2.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31119.1 - 0.5 10.3 5.0 0.67 9.9 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3586 PF12131.8 KDO31120.1 - 0.066 13.4 4.7 0.21 11.8 4.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) LRR_6 PF13516.6 KDO31121.1 - 4.3e-11 41.9 11.9 1.3 9.2 0.0 9.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 KDO31121.1 - 5.9e-11 42.4 11.7 1.4 9.4 0.1 8.3 7 3 2 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO31121.1 - 2.1e-09 36.6 1.7 5.8 7.9 0.4 8.3 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 KDO31121.1 - 1.3e-08 34.5 13.7 0.59 9.9 0.0 8.3 8 1 1 9 9 9 2 Leucine rich repeat F-box PF00646.33 KDO31121.1 - 4.8e-07 29.5 2.8 0.022 14.7 0.3 3.6 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 KDO31121.1 - 3.6e-06 26.8 2.9 0.038 13.9 0.0 2.9 3 0 0 3 3 3 2 F-box-like ACOX PF01756.19 KDO31123.1 - 5.5e-35 120.5 0.1 1.1e-34 119.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KDO31123.1 - 7.4e-14 51.7 0.0 1.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KDO31123.1 - 2.8e-09 37.6 0.0 1.2e-08 35.5 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 KDO31123.1 - 0.00055 20.2 0.6 0.0019 18.4 0.1 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KDO31123.1 - 0.0088 16.7 0.0 0.028 15.1 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FYVE PF01363.21 KDO31124.1 - 5.9e-17 61.6 6.6 1e-16 60.8 6.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO31124.1 - 0.00037 21.1 0.0 0.00095 19.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain C1_2 PF03107.16 KDO31124.1 - 0.56 10.6 7.1 0.47 10.8 4.8 2.0 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.16 KDO31124.1 - 0.62 10.3 3.1 1.1 9.4 3.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger WW PF00397.26 KDO31125.1 - 3.9e-06 26.8 0.4 7.6e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 WW domain DUF4381 PF14316.6 KDO31127.1 - 0.16 12.2 2.9 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) cNMP_binding PF00027.29 KDO31128.1 - 2.1e-09 37.3 0.0 0.00026 21.0 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RAMA PF18755.1 KDO31130.1 - 3e-12 46.9 0.0 2.6e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated PHD PF00628.29 KDO31130.1 - 6.4e-05 22.8 11.1 0.00011 22.0 11.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KDO31130.1 - 0.045 13.7 10.1 0.1 12.5 10.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FlgN PF05130.12 KDO31130.1 - 0.32 11.5 6.3 0.6 10.6 0.1 3.3 3 0 0 3 3 3 0 FlgN protein zf-SNAP50_C PF12251.8 KDO31130.1 - 2.4 7.8 6.8 5 6.7 6.8 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal PRD PF00874.20 KDO31133.1 - 0.072 13.4 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 PRD domain Spc29 PF17082.5 KDO31133.1 - 0.24 11.2 5.4 0.66 9.8 0.2 2.7 3 0 0 3 3 3 0 Spindle Pole Component 29 DASH_Dad3 PF08656.10 KDO31133.1 - 2.1 8.5 0.0 2.1 8.5 0.0 4.1 4 1 0 4 4 4 0 DASH complex subunit Dad3 Pou PF00157.17 KDO31133.1 - 5.2 7.1 6.7 2 8.4 0.1 3.5 4 1 0 4 4 4 0 Pou domain - N-terminal to homeobox domain Filament PF00038.21 KDO31134.1 - 0.00016 21.4 17.4 0.022 14.3 8.1 2.2 1 1 1 2 2 2 2 Intermediate filament protein ADIP PF11559.8 KDO31134.1 - 0.00016 21.8 19.0 0.0035 17.4 6.9 2.3 1 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding ERM PF00769.19 KDO31134.1 - 0.00045 20.1 19.0 0.00055 19.8 19.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family GAS PF13851.6 KDO31134.1 - 0.00059 19.2 20.8 0.0043 16.4 18.3 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2353 PF09789.9 KDO31134.1 - 0.0028 17.1 13.6 0.0033 16.8 13.6 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) APG6_N PF17675.1 KDO31134.1 - 0.0028 18.2 21.1 0.0073 16.8 13.0 2.2 1 1 1 2 2 2 1 Apg6 coiled-coil region Rootletin PF15035.6 KDO31134.1 - 0.0086 16.1 2.2 0.0086 16.1 2.2 2.2 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.7 KDO31134.1 - 0.013 15.6 16.6 0.047 13.8 6.6 2.5 1 1 1 2 2 2 0 Tropomyosin like DUF3584 PF12128.8 KDO31134.1 - 0.018 12.6 18.7 0.021 12.4 18.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KDO31134.1 - 0.026 13.9 12.5 0.032 13.6 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 KDO31134.1 - 0.032 13.8 15.6 0.063 12.9 15.5 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMPIT PF07851.13 KDO31134.1 - 0.049 12.9 9.3 0.035 13.4 7.7 1.5 1 1 0 1 1 1 0 TMPIT-like protein Rx_N PF18052.1 KDO31134.1 - 0.05 13.9 0.9 0.05 13.9 0.9 3.1 1 1 2 3 3 3 0 Rx N-terminal domain LOH1CR12 PF10158.9 KDO31134.1 - 0.06 13.4 6.6 0.2 11.7 0.7 2.3 1 1 1 2 2 2 0 Tumour suppressor protein HrpB7 PF09486.10 KDO31134.1 - 0.07 13.5 17.7 1.5 9.2 17.7 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Prominin PF05478.11 KDO31134.1 - 0.098 10.6 7.2 0.12 10.4 7.2 1.1 1 0 0 1 1 1 0 Prominin ATG16 PF08614.11 KDO31134.1 - 0.1 12.8 22.5 0.038 14.2 19.7 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Vps53_N PF04100.12 KDO31134.1 - 0.1 11.5 10.3 0.86 8.5 2.4 2.1 1 1 1 2 2 2 0 Vps53-like, N-terminal KASH_CCD PF14662.6 KDO31134.1 - 0.11 12.4 19.3 0.12 12.2 16.6 2.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DMPK_coil PF08826.10 KDO31134.1 - 0.13 12.4 15.4 5.9 7.1 2.4 3.5 1 1 2 3 3 3 0 DMPK coiled coil domain like SHE3 PF17078.5 KDO31134.1 - 0.14 11.9 11.6 0.24 11.1 11.2 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Surfac_D-trimer PF09006.11 KDO31134.1 - 0.14 12.0 3.9 1.9 8.5 0.1 3.4 4 0 0 4 4 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3958 PF13125.6 KDO31134.1 - 0.15 12.3 17.0 0.63 10.3 7.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Fez1 PF06818.15 KDO31134.1 - 0.17 12.3 14.7 0.25 11.8 14.7 1.4 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KDO31134.1 - 0.18 10.6 18.6 0.76 8.6 8.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KDO31134.1 - 0.25 11.4 16.1 1.8 8.6 14.5 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KDO31134.1 - 0.25 11.4 12.3 0.7 9.9 2.0 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) KELK PF15796.5 KDO31134.1 - 0.45 11.0 20.1 0.073 13.5 4.0 3.8 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PspA_IM30 PF04012.12 KDO31134.1 - 0.48 10.0 20.3 1.6 8.3 4.9 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF3138 PF11336.8 KDO31134.1 - 0.59 8.7 3.3 0.15 10.6 0.6 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Lebercilin PF15619.6 KDO31134.1 - 0.82 9.3 21.7 1.8 8.2 21.7 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_TACC PF12709.7 KDO31134.1 - 0.89 10.0 13.1 0.48 10.9 0.5 3.3 2 1 1 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Occludin_ELL PF07303.13 KDO31134.1 - 0.9 10.3 10.6 5.2 7.9 1.8 2.6 1 1 2 3 3 3 0 Occludin homology domain FliJ PF02050.16 KDO31134.1 - 1.1 9.5 23.6 0.028 14.7 12.5 2.5 2 1 1 3 3 2 0 Flagellar FliJ protein Tweety PF04906.13 KDO31134.1 - 1.2 7.8 3.2 0.82 8.3 1.2 1.6 1 1 1 2 2 2 0 Tweety CENP-H PF05837.12 KDO31134.1 - 1.2 9.6 21.8 0.3 11.5 8.3 2.5 2 1 1 3 3 2 0 Centromere protein H (CENP-H) MtaB PF12176.8 KDO31134.1 - 1.6 7.5 4.9 3.3 6.4 4.8 1.5 1 1 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit LPP PF04728.13 KDO31134.1 - 1.6 9.2 14.5 0.9 10.0 0.2 3.7 4 0 0 4 4 3 0 Lipoprotein leucine-zipper YlqD PF11068.8 KDO31134.1 - 1.8 8.9 19.0 0.14 12.5 4.2 2.9 1 1 1 2 2 2 0 YlqD protein DUF4200 PF13863.6 KDO31134.1 - 1.9 8.9 18.0 6.2 7.2 13.2 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KDO31134.1 - 1.9 8.5 21.3 2.1 8.4 15.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Spc19 PF08287.11 KDO31134.1 - 2.1 8.2 20.3 0.053 13.4 3.1 2.8 1 1 2 3 3 3 0 Spc19 XLF PF09302.11 KDO31134.1 - 2.6 8.2 9.4 3.9 7.6 0.1 2.8 1 1 2 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Syntaxin-6_N PF09177.11 KDO31134.1 - 2.7 8.6 8.6 7.9 7.1 2.0 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 KDO31134.1 - 3.2 7.3 10.7 4.6 6.8 2.0 2.2 1 1 1 2 2 2 0 fzo-like conserved region THOC7 PF05615.13 KDO31134.1 - 3.6 7.9 16.8 17 5.7 16.6 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2203 PF09969.9 KDO31134.1 - 3.6 8.3 12.5 5.1 7.8 5.0 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) PCRF PF03462.18 KDO31134.1 - 3.7 7.4 15.0 1.1 9.0 5.4 2.2 1 1 1 2 2 2 0 PCRF domain DUF4094 PF13334.6 KDO31134.1 - 3.7 8.0 11.0 5.5 7.5 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 KDO31134.1 - 3.8 7.7 12.8 3.4 7.8 8.2 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KDO31134.1 - 4.4 5.7 13.7 4.8 5.6 13.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.14 KDO31134.1 - 4.4 7.1 14.4 4.5 7.1 11.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KDO31134.1 - 5.6 7.0 18.2 2.5 8.2 15.7 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 KDO31134.1 - 6.6 5.5 8.0 7.7 5.3 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 KDO31134.1 - 7.3 7.1 7.4 9.1 6.8 0.9 3.3 3 1 1 4 4 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 KDO31134.1 - 8.1 6.7 13.5 1.9 8.7 1.6 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 zf-C4H2 PF10146.9 KDO31134.1 - 8.4 6.6 13.1 14 5.9 13.1 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Swi5 PF07061.11 KDO31134.1 - 8.7 6.5 11.7 0.65 10.1 0.7 3.1 1 1 1 2 2 1 0 Swi5 Exonuc_VII_L PF02601.15 KDO31134.1 - 9.2 5.7 18.0 25 4.3 18.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.11 KDO31135.1 - 0.00041 19.4 28.7 0.00054 19.0 28.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4351 PF14261.6 KDO31135.1 - 0.075 13.1 0.8 0.26 11.4 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Cob_adeno_trans PF01923.18 KDO31135.1 - 0.11 12.6 24.4 0.24 11.5 7.2 3.4 1 1 3 4 4 4 0 Cobalamin adenosyltransferase DUF573 PF04504.14 KDO31135.1 - 0.35 11.6 5.7 0.8 10.4 0.1 3.5 3 2 1 4 4 4 0 Protein of unknown function, DUF573 Bcr-Abl_Oligo PF09036.10 KDO31135.1 - 0.79 9.8 6.8 20 5.3 0.0 4.1 2 2 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Golgin_A5 PF09787.9 KDO31135.1 - 1.1 8.7 37.1 0.59 9.6 16.5 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Spc7 PF08317.11 KDO31135.1 - 4.3 6.1 41.0 2.4 6.9 16.8 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KDO31135.1 - 7 7.1 35.2 14 6.0 15.3 2.9 1 1 1 2 2 2 0 Fez1 MFS_1 PF07690.16 KDO31136.1 - 3.1e-37 128.3 22.3 1.1e-25 90.4 4.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO31136.1 - 9.8e-06 24.7 0.3 9.8e-06 24.7 0.3 2.9 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KDO31136.1 - 0.00085 18.3 10.7 0.21 10.4 0.1 3.9 3 1 0 3 3 3 3 MFS_1 like family MFS_1 PF07690.16 KDO31137.1 - 5.6e-15 55.1 14.6 2.2e-10 40.0 8.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KDO31137.1 - 0.0027 16.4 0.2 0.0068 15.1 0.2 1.6 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KDO31137.1 - 0.024 13.5 0.4 0.024 13.5 0.4 2.4 2 1 0 2 2 2 0 MFS_1 like family DUF2070 PF09843.9 KDO31137.1 - 4.1 5.6 12.0 0.14 10.4 5.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) RCC1_2 PF13540.6 KDO31138.1 - 6.5e-17 60.9 15.9 1.6e-07 30.9 0.1 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KDO31138.1 - 2e-12 47.6 8.4 4.2e-05 24.1 0.0 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 KDO31139.1 - 2.8e-31 108.7 24.2 5.4e-21 74.9 7.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO31139.1 - 0.00011 21.2 20.0 0.00012 21.1 1.6 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter Allantoicase PF03561.15 KDO31140.1 - 1.4e-94 313.7 0.0 1.6e-48 164.3 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.7 KDO31141.1 - 6.6e-39 132.4 8.6 5.8e-12 46.0 0.4 7.2 5 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31141.1 - 1.1e-34 118.4 9.3 1.3e-07 32.0 0.0 8.7 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31141.1 - 1.9e-31 104.6 8.1 0.042 14.4 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 KDO31141.1 - 1.6e-25 88.4 11.5 0.0026 18.1 0.0 10.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KDO31141.1 - 7.2e-25 86.7 15.0 0.00011 22.5 0.0 9.7 5 4 3 8 8 8 6 Ankyrin repeats (many copies) Ion_trans PF00520.31 KDO31141.1 - 7.2e-07 28.7 25.7 7.2e-07 28.7 25.7 1.6 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KDO31141.1 - 0.12 11.0 20.8 0.16 10.6 11.1 2.3 1 1 1 2 2 2 0 Polycystin cation channel DUF4231 PF14015.6 KDO31141.1 - 1.7 9.2 5.1 4.9 7.7 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Ank_2 PF12796.7 KDO31142.1 - 7.9e-36 122.5 11.3 1.5e-11 44.7 0.5 7.1 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31142.1 - 2.6e-29 98.0 8.7 0.015 15.7 0.0 13.0 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.6 KDO31142.1 - 2.6e-21 75.4 20.2 1.2e-05 25.4 0.1 9.9 6 4 4 10 10 10 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO31142.1 - 8.2e-18 64.5 15.7 0.01 16.4 0.0 9.4 6 4 6 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO31142.1 - 1.7e-17 63.0 15.0 0.00075 19.8 0.0 9.8 9 0 0 9 9 9 4 Ankyrin repeat Ion_trans PF00520.31 KDO31142.1 - 8e-08 31.8 27.4 1.5e-07 30.9 27.4 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KDO31142.1 - 0.76 8.4 21.2 0.024 13.4 11.3 2.1 1 1 1 2 2 2 0 Polycystin cation channel Baculo_PEP_C PF04513.12 KDO31142.1 - 1.4 9.0 7.2 0.15 12.1 2.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KDO31142.1 - 1.7 9.1 3.7 6.3 7.3 0.4 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Ank_2 PF12796.7 KDO31143.1 - 5e-41 139.2 14.7 1.1e-09 38.7 3.9 7.7 4 2 0 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31143.1 - 1.5e-27 92.6 17.9 0.042 14.4 0.3 12.8 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.6 KDO31143.1 - 3.4e-26 91.3 21.7 1.1e-05 25.9 0.8 10.0 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO31143.1 - 6.3e-22 77.0 25.4 0.01 16.3 1.4 11.0 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KDO31143.1 - 8.2e-15 54.7 20.9 0.005 17.1 0.0 9.2 7 3 2 9 9 9 5 Ankyrin repeats (many copies) Ion_trans PF00520.31 KDO31143.1 - 1.3e-08 34.4 17.3 2.6e-08 33.4 17.3 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KDO31143.1 - 0.015 14.0 19.9 0.11 11.2 12.1 2.2 1 1 1 2 2 2 0 Polycystin cation channel Ank_2 PF12796.7 KDO31144.1 - 1e-42 144.6 16.5 8.5e-12 45.5 0.5 7.4 5 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31144.1 - 1.5e-28 98.8 9.9 1.8e-07 31.6 0.0 8.8 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31144.1 - 5.3e-26 90.3 19.0 6.9e-09 35.8 0.0 9.9 6 3 4 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31144.1 - 6.4e-24 81.4 9.0 0.037 14.6 0.1 11.9 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 KDO31144.1 - 4.3e-19 68.0 20.8 0.011 16.1 0.0 10.7 11 1 0 11 11 11 6 Ankyrin repeat Pox_Ag35 PF03286.14 KDO31144.1 - 0.011 15.5 6.0 0.029 14.2 6.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 KDO31144.1 - 0.1 12.3 10.0 0.18 11.5 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMF_TATA_bd PF12325.8 KDO31144.1 - 0.19 12.0 4.5 9.5 6.5 0.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ion_trans PF00520.31 KDO31144.1 - 0.59 9.3 16.7 1.4 8.1 16.7 1.5 1 0 0 1 1 1 0 Ion transport protein RRN3 PF05327.11 KDO31144.1 - 0.8 8.2 8.6 1.6 7.2 8.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ank_2 PF12796.7 KDO31145.1 - 1.5e-16 60.7 3.2 3.1e-09 37.3 0.2 3.0 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31145.1 - 8.9e-10 38.0 0.5 0.00022 21.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ion_trans PF00520.31 KDO31145.1 - 5.5e-08 32.3 23.6 1e-07 31.5 23.6 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 KDO31145.1 - 9e-08 32.5 0.6 0.0019 18.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO31145.1 - 4.1e-07 30.2 0.8 0.00059 20.2 0.2 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO31145.1 - 3e-06 27.4 4.7 0.00011 22.5 0.2 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF5305 PF17231.2 KDO31145.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ion_trans PF00520.31 KDO31147.1 - 2.5e-06 26.9 15.5 3.9e-06 26.3 15.5 1.2 1 0 0 1 1 1 1 Ion transport protein DUF3206 PF11472.8 KDO31147.1 - 0.045 13.8 0.2 0.09 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Pec_lyase_C PF00544.19 KDO31148.1 - 6.4e-07 29.2 5.4 6.2e-06 25.9 5.4 2.1 1 1 0 1 1 1 1 Pectate lyase Ank_2 PF12796.7 KDO31149.1 - 1.6e-28 99.1 5.9 1.6e-11 44.6 0.6 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31149.1 - 3e-21 73.2 4.8 0.0034 17.8 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KDO31149.1 - 2.9e-15 55.9 9.0 2.7e-05 24.4 0.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KDO31149.1 - 5.9e-15 55.1 3.8 5e-06 26.7 0.4 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO31149.1 - 1.9e-14 53.8 1.7 0.0013 19.2 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) PKD_channel PF08016.12 KDO31149.1 - 0.0095 14.7 17.1 0.0094 14.7 10.8 2.4 2 0 0 2 2 2 2 Polycystin cation channel Ank_2 PF12796.7 KDO31150.1 - 5.9e-19 68.5 2.4 2.8e-10 40.6 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31150.1 - 8.5e-18 64.5 2.3 4.4e-09 36.7 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31150.1 - 7.2e-15 53.6 2.0 0.0051 17.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KDO31150.1 - 2.1e-12 46.9 4.3 0.0096 16.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KDO31150.1 - 4.3e-12 46.0 2.9 4.5e-06 26.8 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF4611 PF15387.6 KDO31150.1 - 0.15 12.3 3.4 0.24 11.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 KDO31150.1 - 0.18 11.4 0.7 0.27 10.9 0.7 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KDO31150.1 - 6.9 5.9 6.1 9.3 5.5 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 KDO31151.1 - 1.4e-23 83.4 37.1 1.1e-16 60.7 23.6 3.5 3 2 0 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 KDO31154.1 - 3.3e-22 78.9 23.3 2.5e-12 46.4 6.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PhnJ PF06007.11 KDO31154.1 - 0.035 13.1 0.8 0.17 10.9 0.1 1.9 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnJ DUF1464 PF07318.12 KDO31154.1 - 0.24 10.5 0.2 0.37 9.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Pkinase_Tyr PF07714.17 KDO31155.1 - 1.4e-116 388.3 0.0 3.9e-58 196.8 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KDO31155.1 - 2e-101 338.8 0.0 1.7e-49 168.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Haspin_kinase PF12330.8 KDO31155.1 - 1.5e-06 27.4 0.0 0.31 9.9 0.0 4.1 4 0 0 4 4 4 3 Haspin like kinase domain APH PF01636.23 KDO31155.1 - 4e-06 26.9 0.5 0.049 13.6 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO31155.1 - 0.00033 19.6 0.0 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KDO31155.1 - 0.069 12.5 0.0 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like dCMP_cyt_deam_1 PF00383.23 KDO31156.1 - 3.6e-08 33.2 0.8 6.8e-08 32.3 0.8 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KDO31156.1 - 5.5e-06 26.2 0.1 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KDO31156.1 - 0.0038 17.3 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase ABC_membrane PF00664.23 KDO31157.1 - 3.1e-37 128.7 2.2 3.9e-37 128.4 2.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO31157.1 - 4.6e-33 114.6 0.0 9.6e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KDO31157.1 - 6.3e-09 35.6 1.4 8.2e-06 25.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KDO31157.1 - 0.00023 21.1 0.1 0.005 16.7 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO31157.1 - 0.00029 20.7 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KDO31157.1 - 0.0012 18.1 0.1 0.0028 16.9 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KDO31157.1 - 0.0022 17.7 0.9 0.005 16.5 0.9 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO31157.1 - 0.0026 18.0 0.1 0.0095 16.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KDO31157.1 - 0.0028 18.0 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KDO31157.1 - 0.0032 17.4 0.1 0.0073 16.2 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 KDO31157.1 - 0.0052 15.6 0.5 0.015 14.1 0.5 1.7 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KDO31157.1 - 0.028 14.9 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KDO31157.1 - 0.029 14.1 0.1 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO31157.1 - 0.045 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KDO31157.1 - 0.052 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 KDO31157.1 - 0.069 13.7 0.0 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO31157.1 - 0.089 13.0 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KDO31158.1 - 1.2e-13 51.1 0.1 5.1e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO31158.1 - 7.5e-11 42.2 0.4 3e-10 40.3 0.4 1.9 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KDO31158.1 - 3.9e-08 33.0 0.7 1.4e-05 24.7 0.2 2.6 2 1 0 2 2 2 2 Ferrous iron transport protein B AAA_29 PF13555.6 KDO31158.1 - 0.032 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KDO31158.1 - 0.044 12.8 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MCM PF00493.23 KDO31158.1 - 0.046 12.8 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 KDO31158.1 - 0.072 13.3 0.3 0.25 11.6 0.0 2.0 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KDO31158.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain 7tm_3 PF00003.22 KDO31159.1 - 4.2e-10 39.7 10.0 6.6e-10 39.1 9.4 1.6 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PI3Ka PF00613.20 KDO31159.1 - 1e-09 38.1 0.1 1.6e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HEAT_EZ PF13513.6 KDO31159.1 - 0.00074 20.0 2.6 0.17 12.4 0.1 3.8 3 0 0 3 3 3 1 HEAT-like repeat EGF_2 PF07974.13 KDO31159.1 - 0.0097 16.3 10.0 0.0097 16.3 10.0 2.6 1 1 2 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 KDO31159.1 - 0.052 13.6 5.1 0.19 11.8 5.1 2.1 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 KDO31159.1 - 0.12 12.7 2.7 0.42 11.0 2.8 1.8 1 1 0 1 1 1 0 EGF-like domain HA PF03457.14 KDO31160.1 - 1.5e-16 60.5 0.6 4e-08 33.5 0.2 3.0 3 0 0 3 3 3 2 Helicase associated domain CBM_1 PF00734.18 KDO31161.1 - 1.5e-05 24.9 28.7 4.2e-05 23.4 9.6 3.3 2 2 0 2 2 2 2 Fungal cellulose binding domain MapZ_EC1 PF18041.1 KDO31164.1 - 0.00024 21.3 3.0 0.0005 20.3 3.0 1.5 1 0 0 1 1 1 1 MapZ extracellular domain 1 Enkurin PF13864.6 KDO31164.1 - 0.0034 17.8 6.2 0.0051 17.2 2.6 2.2 2 0 0 2 2 2 1 Calmodulin-binding Serine_rich PF08824.10 KDO31164.1 - 0.031 14.3 1.7 0.066 13.2 1.7 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain LCD1 PF09798.9 KDO31164.1 - 0.075 11.5 2.4 0.11 11.0 2.4 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein NPV_P10 PF05531.12 KDO31164.1 - 2.3 8.7 4.6 12 6.4 3.8 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YmgD PF16456.5 KDO31164.1 - 6.2 7.0 6.7 7.4 6.7 1.0 2.7 2 1 1 3 3 3 0 YmgD protein CBM_1 PF00734.18 KDO31166.1 - 6e-18 64.5 32.1 1.3e-09 37.8 5.1 3.7 3 0 0 3 3 3 3 Fungal cellulose binding domain 2-Hacid_dh_C PF02826.19 KDO31167.1 - 1.9e-44 151.1 0.3 1.5e-43 148.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO31167.1 - 4.3e-30 104.1 0.1 9.4e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KDO31167.1 - 3.8e-07 29.8 0.0 1.2e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 KDO31167.1 - 3.8e-05 23.9 0.0 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KDO31167.1 - 0.02 15.5 0.0 0.055 14.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ACT_6 PF13740.6 KDO31167.1 - 0.038 14.0 0.0 0.15 12.1 0.0 2.1 1 0 0 1 1 1 0 ACT domain zf-BED PF02892.15 KDO31168.1 - 0.0044 17.0 7.1 0.0078 16.2 7.1 1.4 1 0 0 1 1 1 1 BED zinc finger zf-C2HE PF16278.5 KDO31168.1 - 0.0086 16.5 1.8 0.019 15.4 1.8 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Asp_Glu_race_2 PF14669.6 KDO31169.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative aspartate racemase Metallophos PF00149.28 KDO31170.1 - 3.4e-14 53.8 0.0 5.3e-14 53.2 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO31170.1 - 3.3e-05 24.1 0.1 4.9e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YqzE PF14038.6 KDO31172.1 - 0.049 13.6 0.2 0.17 11.9 0.2 1.9 1 0 0 1 1 1 0 YqzE-like protein Acyl_transf_3 PF01757.22 KDO31174.1 - 4.9e-20 71.9 36.7 2.2e-19 69.7 33.6 2.8 1 1 1 2 2 2 1 Acyltransferase family MASE4 PF17158.4 KDO31174.1 - 0.0047 16.2 0.3 0.0047 16.2 0.3 2.5 2 0 0 2 2 2 1 Membrane-associated sensor, integral membrane domain Ank_2 PF12796.7 KDO31175.1 - 6.3e-157 510.6 34.5 2.6e-16 60.0 0.6 13.4 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31175.1 - 1.7e-113 356.7 18.3 0.001 19.3 0.0 28.0 28 0 0 28 28 28 24 Ankyrin repeat Ank_4 PF13637.6 KDO31175.1 - 5.7e-113 368.0 32.5 2.2e-09 37.6 0.1 20.5 5 5 19 24 24 24 24 Ankyrin repeats (many copies) Ank PF00023.30 KDO31175.1 - 1.4e-109 354.2 68.6 1.5e-05 25.2 0.0 27.6 28 0 0 28 28 28 25 Ankyrin repeat Ank_5 PF13857.6 KDO31175.1 - 1.2e-87 286.9 50.0 5.7e-08 32.9 0.5 19.8 7 5 15 22 22 22 22 Ankyrin repeats (many copies) GATase_7 PF13537.6 KDO31175.1 - 9.2e-06 25.6 0.4 1.6e+02 2.2 0.0 9.5 9 3 4 13 13 13 0 Glutamine amidotransferase domain PEGA PF08308.11 KDO31175.1 - 0.023 14.6 2.0 84 3.2 0.0 6.6 8 0 0 8 8 8 0 PEGA domain Imm_superinfect PF14373.6 KDO31175.1 - 0.083 12.8 17.0 35 4.4 0.0 10.7 15 0 0 15 15 15 0 Superinfection immunity protein Prion_bPrPp PF11587.8 KDO31175.1 - 0.12 12.2 0.1 1 9.2 0.1 2.7 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal 17kDa_Anti_2 PF16998.5 KDO31175.1 - 0.31 11.0 1.9 7.5 6.5 0.0 3.4 3 1 0 3 3 3 0 17 kDa outer membrane surface antigen DAP10 PF07213.11 KDO31175.1 - 9.1 6.3 11.1 3.4 7.7 0.9 4.7 5 1 1 6 6 6 0 DAP10 membrane protein Gp_dh_N PF00044.24 KDO31176.1 - 5.5e-40 135.8 0.0 6.4e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KDO31176.1 - 0.023 14.8 0.0 0.032 14.4 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KDO31176.1 - 0.054 12.9 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.7 KDO31177.1 - 3.1e-19 69.3 1.7 2.3e-18 66.4 2.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO31177.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Gp_dh_C PF02800.20 KDO31178.1 - 7.7e-65 217.3 0.0 9.8e-65 217.0 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KDO31178.1 - 3.3e-08 33.8 0.9 1.4e-07 31.7 0.3 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RII_binding_1 PF10522.9 KDO31178.1 - 0.043 14.0 0.0 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 RII binding domain 2-Hacid_dh_C PF02826.19 KDO31178.1 - 0.045 13.1 0.1 0.078 12.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF5408 PF17402.2 KDO31179.1 - 1.7 8.6 3.4 3.7 7.5 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DNA_photolyase PF00875.18 KDO31180.1 - 1.4e-17 64.2 0.0 3e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KDO31180.1 - 0.015 15.8 0.0 0.081 13.4 0.0 2.2 2 0 0 2 2 2 0 Universal stress protein family BK_channel_a PF03493.18 KDO31181.1 - 5.4e-23 81.0 0.1 5.2e-21 74.7 0.0 2.5 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Cation_ATPase_C PF00689.21 KDO31182.1 - 1.9e-46 158.0 2.3 1.9e-46 158.0 2.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO31182.1 - 1.2e-33 116.2 8.1 4.6e-22 78.4 0.3 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 KDO31182.1 - 1.8e-18 66.4 0.0 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO31182.1 - 3.2e-16 60.3 0.1 9.3e-15 55.5 0.2 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO31182.1 - 3.7e-14 52.1 0.0 8.3e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus ATP_Ca_trans_C PF12424.8 KDO31182.1 - 4.4e-05 23.9 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 KDO31182.1 - 0.00018 21.4 0.5 0.0057 16.4 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P22_Cro PF14549.6 KDO31182.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro TRM PF02005.16 KDO31183.1 - 2.7e-123 411.9 0.0 3.2e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Zn_ribbon_SprT PF17283.2 KDO31183.1 - 0.022 14.6 0.8 0.66 9.9 0.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Cons_hypoth95 PF03602.15 KDO31183.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.16 KDO31183.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Zn-ribbon_8 PF09723.10 KDO31183.1 - 0.16 12.1 1.2 0.58 10.3 1.2 2.0 1 1 0 1 1 1 0 Zinc ribbon domain UCH PF00443.29 KDO31184.1 - 3.9e-69 233.0 0.0 5e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO31184.1 - 1.4e-12 47.9 0.0 7e-09 35.7 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KDO31184.1 - 2.8e-09 37.5 0.0 6.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 DUSP domain EF-hand_7 PF13499.6 KDO31184.1 - 0.031 14.7 0.6 2.9 8.4 0.0 3.4 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 KDO31184.1 - 0.048 13.6 0.1 31 4.9 0.0 3.4 2 0 0 2 2 2 0 EF-hand domain Peptidase_M20 PF01546.28 KDO31185.1 - 1.6e-22 80.3 0.3 2.3e-22 79.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO31185.1 - 1.2e-08 34.8 0.2 5.5e-08 32.7 0.2 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain UDG PF03167.19 KDO31189.1 - 1e-12 48.3 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily APH PF01636.23 KDO31190.1 - 4.6e-13 49.7 1.0 1.4e-12 48.1 1.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FAD-oxidase_C PF02913.19 KDO31190.1 - 0.045 13.4 0.1 0.097 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Arm PF00514.23 KDO31191.1 - 2.4e-11 43.2 35.6 0.0061 16.6 0.0 12.4 14 0 0 14 14 14 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO31191.1 - 0.0044 17.4 5.9 0.19 12.2 0.2 5.7 5 1 1 6 6 6 1 HEAT repeats UNC45-central PF11701.8 KDO31191.1 - 0.0074 16.2 0.1 0.0074 16.2 0.1 4.9 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 KDO31191.1 - 0.26 11.5 1.2 44 4.3 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF383 PF04063.14 KDO31191.1 - 3.2 7.4 5.5 3.8 7.1 0.4 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF383) RICTOR_N PF14664.6 KDO31191.1 - 4.3 6.2 14.6 0.07 12.1 2.2 3.7 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term DDA1 PF10172.9 KDO31192.1 - 3.6e-12 46.4 0.1 6.3e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase HECT PF00632.25 KDO31194.1 - 2.2e-83 280.3 0.0 3.2e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zinc_ribbon_11 PF11682.8 KDO31194.1 - 0.078 13.0 0.2 0.75 9.8 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon zf-RanBP PF00641.18 KDO31194.1 - 0.088 12.1 2.0 0.14 11.5 0.3 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pkinase PF00069.25 KDO31195.1 - 1e-50 172.5 0.0 9.1e-35 120.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31195.1 - 2.8e-27 95.6 0.0 1.9e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO31195.1 - 2.4e-08 33.6 0.1 3.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KDO31195.1 - 2.8e-06 27.4 1.6 0.005 16.8 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO31195.1 - 6.2e-05 22.1 0.0 8.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO31195.1 - 0.00061 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO31195.1 - 0.0028 17.3 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KDO31195.1 - 0.044 12.6 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KDO31195.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA_m1G_MT PF01746.21 KDO31196.1 - 0.00064 19.5 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Orn_Arg_deC_N PF02784.16 KDO31197.1 - 7.9e-38 130.2 0.0 1.1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KDO31197.1 - 3.8e-14 52.7 0.0 6.6e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LtrA PF06772.11 KDO31198.1 - 1.1e-47 163.0 34.9 1.7e-47 162.4 34.9 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Metallophos PF00149.28 KDO31198.1 - 1.6e-11 45.1 0.1 3e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_U57 PF05582.12 KDO31198.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 TPR_14 PF13428.6 KDO31199.1 - 8.2e-18 63.6 14.8 0.00022 21.8 0.2 9.8 4 2 6 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31199.1 - 1.2e-14 53.2 12.4 0.028 14.5 0.0 8.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31199.1 - 1e-10 42.1 6.4 0.02 15.5 0.0 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO31199.1 - 3.1e-10 40.4 14.3 9.2e-06 26.1 0.3 6.0 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KDO31199.1 - 1.9e-09 37.5 10.9 0.068 13.3 0.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO31199.1 - 4.7e-09 36.4 15.3 0.0079 16.5 0.0 7.4 6 1 1 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO31199.1 - 2.2e-08 33.9 5.7 0.015 15.6 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO31199.1 - 1.5e-07 31.0 4.5 0.44 10.7 0.1 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31199.1 - 2e-07 30.6 9.2 0.94 9.9 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO31199.1 - 2.3e-07 30.9 5.7 0.00025 21.2 1.3 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KDO31199.1 - 6e-07 29.7 5.8 0.47 10.8 0.1 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO31199.1 - 6.2e-07 29.7 12.3 1.1 10.0 0.0 8.1 10 0 0 10 10 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31199.1 - 2.6e-06 27.0 14.6 0.055 13.3 0.0 6.9 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO31199.1 - 7.3e-06 25.6 3.5 0.075 12.7 0.0 5.3 4 1 2 6 6 6 1 TPR repeat TPR_15 PF13429.6 KDO31199.1 - 0.00035 19.9 4.9 0.035 13.3 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat CDC45 PF02724.14 KDO31199.1 - 0.0052 15.1 16.8 0.054 11.8 3.9 2.2 2 0 0 2 2 2 2 CDC45-like protein BUD22 PF09073.10 KDO31199.1 - 0.014 14.8 15.3 0.014 14.7 1.7 2.2 2 0 0 2 2 2 0 BUD22 FAT PF02259.23 KDO31199.1 - 0.055 12.7 0.5 0.35 10.0 0.2 2.2 3 1 0 3 3 3 0 FAT domain Mpp10 PF04006.12 KDO31199.1 - 1.3 7.3 20.2 0.31 9.4 6.0 2.5 3 0 0 3 3 3 0 Mpp10 protein TPR_4 PF07721.14 KDO31199.1 - 3.1 8.7 11.0 22 6.1 0.0 5.6 5 1 0 5 5 4 0 Tetratricopeptide repeat eIF-3c_N PF05470.12 KDO31199.1 - 3.4 5.9 9.5 2.6 6.2 1.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM176 PF14851.6 KDO31199.1 - 3.7 7.2 17.5 0.57 9.8 6.4 2.5 2 0 0 2 2 2 0 FAM176 family SDA1 PF05285.12 KDO31199.1 - 4.8 6.5 27.5 0.011 15.1 4.4 2.4 2 1 0 2 2 2 0 SDA1 RPN2_C PF18004.1 KDO31199.1 - 7.1 6.5 5.9 0.97 9.3 0.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain NARP1 PF12569.8 KDO31199.1 - 7.4 5.4 14.2 0.61 8.9 0.0 2.8 3 0 0 3 3 2 0 NMDA receptor-regulated protein 1 TubC_N PF18563.1 KDO31200.1 - 0.08 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 TubC N-terminal docking domain V-SNARE PF05008.15 KDO31200.1 - 0.39 11.1 5.8 1.4 9.4 0.5 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.12 KDO31200.1 - 1.1 9.8 5.9 0.22 12.0 0.4 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 KDO31200.1 - 8.9 6.7 8.4 0.2 12.0 0.9 2.1 3 0 0 3 3 3 0 Tup N-terminal FAD_binding_1 PF00667.20 KDO31201.1 - 7.2e-50 169.6 0.0 2.1e-39 135.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Flavodoxin_1 PF00258.25 KDO31201.1 - 6.8e-31 107.4 0.2 1.2e-30 106.6 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KDO31201.1 - 4.9e-16 59.3 0.0 1.4e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POPLD PF08170.12 KDO31202.1 - 3.4e-16 59.3 0.0 7.5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.11 KDO31202.1 - 6e-13 49.3 6.5 8.8e-09 35.7 0.5 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 Aa_trans PF01490.18 KDO31204.1 - 6.5e-42 143.7 22.5 8.7e-42 143.3 22.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO31204.1 - 1.2e-05 24.6 7.5 1.2e-05 24.6 7.5 2.9 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family DDE_1 PF03184.19 KDO31205.1 - 2.7e-07 30.4 0.0 3.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease WHH PF14414.6 KDO31205.1 - 0.3 11.0 2.7 19 5.2 0.4 3.2 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH Ribosomal_L6 PF00347.23 KDO31207.1 - 3.5e-29 101.3 0.8 4.8e-15 56.0 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HtaA PF04213.13 KDO31207.1 - 0.11 13.0 0.2 2.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Htaa DUF3450 PF11932.8 KDO31209.1 - 4.7e-05 22.8 21.8 0.0026 17.1 4.5 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) DUF4618 PF15397.6 KDO31209.1 - 5.4e-05 22.7 12.0 0.0066 15.9 3.5 2.7 1 1 1 3 3 3 2 Domain of unknown function (DUF4618) APG6_N PF17675.1 KDO31209.1 - 0.00017 22.1 23.5 0.061 13.8 13.9 3.0 1 1 1 2 2 2 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KDO31209.1 - 0.00033 20.7 14.8 0.021 14.9 5.4 2.9 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 KDO31209.1 - 0.0006 19.6 6.9 0.0019 18.0 2.8 2.1 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 HALZ PF02183.18 KDO31209.1 - 0.00078 19.6 6.7 2.8 8.2 0.1 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 KDO31209.1 - 0.0017 18.6 9.8 0.98 9.7 2.1 3.4 2 2 0 3 3 3 1 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 KDO31209.1 - 0.0017 18.3 13.6 0.08 13.0 2.6 3.1 1 1 2 3 3 3 1 Laminin Domain II BRE1 PF08647.11 KDO31209.1 - 0.0036 17.3 13.4 0.16 12.0 0.5 3.3 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 KDO31209.1 - 0.0037 17.1 11.1 0.0037 17.1 11.1 1.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KDO31209.1 - 0.0062 15.5 10.0 0.0062 15.5 10.0 2.6 1 1 2 3 3 3 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KDO31209.1 - 0.0069 16.4 1.8 0.0069 16.4 1.8 3.0 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 KDO31209.1 - 0.0092 16.4 2.6 0.0092 16.4 2.6 2.9 1 1 1 3 3 3 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KDO31209.1 - 0.0095 16.0 10.0 0.61 10.1 1.4 3.3 1 1 2 4 4 4 1 Protein of unknown function (DUF1664) DUF5339 PF17274.2 KDO31209.1 - 0.01 16.7 1.9 0.16 12.8 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5339) bZIP_1 PF00170.21 KDO31209.1 - 0.016 15.3 2.6 7.6 6.7 0.0 4.1 3 1 0 4 4 4 0 bZIP transcription factor TolA_bind_tri PF16331.5 KDO31209.1 - 0.021 14.9 0.7 0.021 14.9 0.7 3.6 3 1 1 4 4 3 0 TolA binding protein trimerisation ATG16 PF08614.11 KDO31209.1 - 0.022 15.0 26.1 0.27 11.4 10.3 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 KDO31209.1 - 0.026 14.9 34.0 0.18 12.2 16.2 3.4 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) SPATA9 PF15824.5 KDO31209.1 - 0.036 13.3 0.3 0.06 12.6 0.3 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Taxilin PF09728.9 KDO31209.1 - 0.046 12.9 12.6 0.11 11.7 1.0 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Seryl_tRNA_N PF02403.22 KDO31209.1 - 0.055 13.7 10.1 0.9 9.8 4.2 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 KDO31209.1 - 0.056 13.7 18.4 0.76 10.0 8.1 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Shugoshin_N PF07558.11 KDO31209.1 - 0.059 13.2 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Fib_alpha PF08702.10 KDO31209.1 - 0.064 13.4 7.7 1.8 8.7 4.8 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KDO31209.1 - 0.065 13.7 6.9 1.5 9.4 0.5 3.5 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein HAUS-augmin3 PF14932.6 KDO31209.1 - 0.068 12.7 21.5 0.092 12.3 12.1 2.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Wtap PF17098.5 KDO31209.1 - 0.078 12.9 12.1 0.62 10.0 1.4 3.1 1 1 2 3 3 3 0 WTAP/Mum2p family FapA PF03961.13 KDO31209.1 - 0.11 11.0 5.2 0.52 8.8 2.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF724 PF05266.14 KDO31209.1 - 0.13 12.1 10.5 0.083 12.7 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 KDO31209.1 - 0.14 11.5 18.8 0.57 9.5 2.4 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2046 PF09755.9 KDO31209.1 - 0.14 11.4 11.4 0.18 11.0 9.8 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) JIP_LZII PF16471.5 KDO31209.1 - 0.16 12.2 4.1 0.5 10.6 0.3 3.3 1 1 1 3 3 3 0 JNK-interacting protein leucine zipper II RasGAP_C PF03836.15 KDO31209.1 - 0.16 12.1 7.1 0.68 10.1 0.2 3.0 1 1 2 3 3 3 0 RasGAP C-terminus DUF4686 PF15742.5 KDO31209.1 - 0.18 10.9 19.3 0.31 10.1 19.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Prominin PF05478.11 KDO31209.1 - 0.2 9.6 11.7 0.67 7.8 2.5 2.0 1 1 1 2 2 2 0 Prominin PspA_IM30 PF04012.12 KDO31209.1 - 0.24 10.9 28.6 2.6 7.5 17.6 2.9 1 1 1 2 2 2 0 PspA/IM30 family COG5 PF10392.9 KDO31209.1 - 0.25 11.5 9.2 0.26 11.5 4.4 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 KDO31209.1 - 0.3 11.1 8.1 1.5e+02 2.4 7.7 2.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KDO31209.1 - 0.3 9.7 10.7 0.92 8.1 10.7 1.8 1 1 0 1 1 1 0 AAA domain zf-C4H2 PF10146.9 KDO31209.1 - 0.31 11.3 12.4 0.069 13.4 6.2 2.1 1 1 0 2 2 2 0 Zinc finger-containing protein Troponin PF00992.20 KDO31209.1 - 0.41 11.0 12.6 0.99 9.7 1.1 3.3 1 1 2 3 3 3 0 Troponin DUF16 PF01519.16 KDO31209.1 - 0.52 10.8 9.5 1e+02 3.5 9.5 3.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cnn_1N PF07989.11 KDO31209.1 - 0.55 10.4 9.6 2.1 8.6 0.6 3.4 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF3958 PF13125.6 KDO31209.1 - 0.62 10.3 12.7 3.1 8.0 0.4 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DUF4472 PF14739.6 KDO31209.1 - 0.65 10.8 16.8 13 6.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) SKA1 PF07160.12 KDO31209.1 - 0.66 9.8 7.5 0.45 10.3 0.7 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Leu_zip PF15294.6 KDO31209.1 - 0.67 9.4 11.8 1.2 8.6 7.1 2.2 1 1 1 2 2 2 0 Leucine zipper GAT PF03127.14 KDO31209.1 - 0.71 10.2 6.6 3.7 7.9 0.1 3.8 3 1 1 4 4 3 0 GAT domain AIP3 PF03915.13 KDO31209.1 - 0.78 8.8 11.7 1.1 8.3 11.7 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Sipho_Gp157 PF05565.11 KDO31209.1 - 0.9 9.5 11.4 0.27 11.2 0.6 2.7 1 1 2 3 3 3 0 Siphovirus Gp157 UPF0242 PF06785.11 KDO31209.1 - 1 9.4 17.9 2.6 8.1 8.3 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KDO31209.1 - 1 9.1 20.9 0.7 9.7 3.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SYCE1 PF15233.6 KDO31209.1 - 1.1 9.3 14.9 1.6 8.8 7.5 2.6 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 ZapB PF06005.12 KDO31209.1 - 1.4 9.4 18.6 6.4 7.3 4.3 4.3 1 1 3 4 4 4 0 Cell division protein ZapB LPP PF04728.13 KDO31209.1 - 1.4 9.3 17.1 0.79 10.2 1.5 4.2 4 1 0 4 4 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 KDO31209.1 - 1.5 9.1 5.4 13 6.1 0.4 3.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Lectin_N PF03954.14 KDO31209.1 - 1.7 8.4 11.0 17 5.2 0.4 3.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Mod_r PF07200.13 KDO31209.1 - 1.7 8.7 19.5 6.9 6.8 3.2 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF641 PF04859.12 KDO31209.1 - 2 8.8 11.4 9 6.6 1.0 3.1 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 KDO31209.1 - 2.3 7.4 10.0 6.9 5.8 4.3 2.2 1 1 0 2 2 2 0 TMPIT-like protein THOC7 PF05615.13 KDO31209.1 - 2.7 8.3 17.0 6.2e+03 -2.6 16.4 2.9 1 1 0 1 1 0 0 Tho complex subunit 7 TLE_N PF03920.15 KDO31209.1 - 3.1 7.9 8.9 16 5.5 0.1 3.4 1 1 2 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Lebercilin PF15619.6 KDO31209.1 - 3.6 7.2 18.5 6.4 6.4 18.4 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.11 KDO31209.1 - 3.8 6.3 23.1 6 5.6 23.1 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 KDO31209.1 - 4.7 7.3 24.6 1.4e+02 2.6 14.3 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KDO31209.1 - 5.6 7.3 13.9 7.2 6.9 2.9 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KDO31209.1 - 6.7 6.0 19.8 11 5.3 10.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 KDO31209.1 - 7.8 7.2 7.2 71 4.1 0.2 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 KDO31209.1 - 9.3 6.4 22.2 0.23 11.6 3.2 3.7 2 2 0 3 3 3 0 Centrosome localisation domain of PPC89 BK_channel_a PF03493.18 KDO31210.1 - 3.1e-20 72.2 0.3 1.3e-18 66.9 0.1 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 KDO31210.1 - 9.1e-07 29.1 0.1 0.008 16.4 0.1 2.4 2 0 0 2 2 2 2 TrkA-N domain Methyltransf_25 PF13649.6 KDO31211.1 - 0.15 12.8 0.2 1.1 10.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain NEL PF14496.6 KDO31211.1 - 0.16 11.3 0.2 0.23 10.8 0.2 1.2 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting Metallophos PF00149.28 KDO31212.1 - 1.2e-09 38.9 0.1 1.9e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hydrolase_4 PF12146.8 KDO31213.1 - 2.3e-10 40.1 0.4 1.6e-07 30.8 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO31213.1 - 4.7e-06 27.4 1.6 0.0003 21.5 0.1 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO31213.1 - 5.2e-06 26.3 0.2 0.00017 21.3 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KDO31213.1 - 8.1e-06 25.5 0.0 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KDO31213.1 - 0.0041 16.9 0.1 0.028 14.2 0.1 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 KDO31213.1 - 0.028 13.4 0.4 0.062 12.2 0.2 1.6 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KDO31213.1 - 0.079 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KDO31213.1 - 0.093 12.3 0.1 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Asp2 PF16929.5 KDO31213.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Flavodoxin_1 PF00258.25 KDO31214.1 - 7.1e-21 74.9 0.1 1.2e-20 74.2 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KDO31214.1 - 1.1e-09 38.2 0.1 9.1e-05 22.1 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 KDO31214.1 - 7.4e-05 23.4 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 KDO31214.1 - 0.0043 17.2 0.1 0.0085 16.3 0.1 1.4 1 0 0 1 1 1 1 NrdI Flavodoxin like PET117 PF15786.5 KDO31215.1 - 4.1e-08 33.4 5.5 7.1e-08 32.6 5.5 1.4 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial UPF0767 PF15990.5 KDO31215.1 - 0.049 13.8 0.1 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 UPF0767 family DUF4071 PF13281.6 KDO31215.1 - 0.15 11.1 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Ank_2 PF12796.7 KDO31216.1 - 0.00014 22.4 0.0 0.00037 21.0 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31216.1 - 0.0014 19.0 0.4 0.13 12.9 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KDO31216.1 - 0.0027 18.0 0.3 1.5 9.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO31216.1 - 0.15 12.7 0.1 0.48 11.1 0.1 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) YabA PF06156.13 KDO31216.1 - 1.3 9.7 5.7 0.37 11.5 1.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA SLX9 PF15341.6 KDO31217.1 - 1.1e-14 55.0 7.2 1.6e-14 54.4 7.2 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Sec2p PF06428.11 KDO31217.1 - 0.0013 18.6 1.3 0.0027 17.6 1.3 1.6 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DHC_N1 PF08385.12 KDO31218.1 - 1.4e-180 601.7 13.1 1.4e-180 601.7 13.1 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KDO31218.1 - 9.3e-142 471.8 0.0 8.4e-141 468.7 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO31218.1 - 8.1e-115 384.1 17.7 8.1e-115 384.1 17.7 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO31218.1 - 1.3e-86 290.2 0.1 2.8e-85 285.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO31218.1 - 3.3e-72 242.2 0.0 1e-71 240.6 0.0 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KDO31218.1 - 1.5e-59 200.6 0.4 8.1e-55 185.1 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 KDO31218.1 - 8e-37 127.0 10.2 2e-36 125.7 10.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KDO31218.1 - 1.1e-17 64.3 0.0 5.2e-17 62.1 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO31218.1 - 4.9e-16 58.8 0.5 7.3e-15 55.0 0.5 2.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO31218.1 - 1.4e-12 47.8 0.1 3.4e-05 23.9 0.0 5.2 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO31218.1 - 4.9e-05 23.6 1.3 11 6.2 0.1 5.1 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 KDO31218.1 - 5.4e-05 23.7 0.2 6.7 7.1 0.0 5.5 5 0 0 5 5 5 1 AAA ATPase domain AAA PF00004.29 KDO31218.1 - 0.0011 19.5 7.3 0.35 11.3 0.1 5.3 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO31218.1 - 0.0037 17.8 0.1 6.4 7.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KDO31218.1 - 0.014 15.9 0.0 17 5.9 0.0 3.4 2 0 0 2 2 2 0 ABC transporter DUF3583 PF12126.8 KDO31218.1 - 0.03 13.8 0.0 0.1 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) His_Phos_2 PF00328.22 KDO31218.1 - 0.032 13.6 0.0 0.088 12.1 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_29 PF13555.6 KDO31218.1 - 0.04 13.7 0.1 4.4 7.1 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain MLD PF11647.8 KDO31218.1 - 0.057 13.7 2.4 45 4.4 0.1 4.7 4 0 0 4 4 4 0 Membrane Localization Domain AAA_33 PF13671.6 KDO31218.1 - 0.06 13.5 0.8 31 4.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KDO31218.1 - 0.063 13.7 0.1 9 6.7 0.0 3.6 2 0 0 2 2 2 0 RNA helicase PI_PP_I PF18363.1 KDO31218.1 - 0.13 12.5 8.0 19 5.5 0.1 5.3 5 0 0 5 5 3 0 Phosphoinositide phosphatase insertion domain ACDC PF14733.6 KDO31218.1 - 0.16 12.3 0.7 2.7 8.4 0.1 3.1 2 0 0 2 2 2 0 AP2-coincident C-terminal AAA_28 PF13521.6 KDO31218.1 - 0.19 12.0 5.0 5.7 7.2 0.1 3.8 3 0 0 3 3 3 0 AAA domain MA3 PF02847.17 KDO31218.1 - 0.36 10.8 5.0 0.67 10.0 1.0 3.3 2 0 0 2 2 2 0 MA3 domain AAA_23 PF13476.6 KDO31218.1 - 0.55 10.7 0.0 0.55 10.7 0.0 5.4 6 1 0 6 6 3 0 AAA domain HOOK PF05622.12 KDO31219.1 - 0.026 12.7 10.2 0.05 11.7 10.2 1.4 1 0 0 1 1 1 0 HOOK protein FAD-SLDH PF12318.8 KDO31219.1 - 0.093 12.8 1.7 0.25 11.4 0.4 2.3 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4795 PF16043.5 KDO31219.1 - 0.12 12.0 8.9 0.23 11.1 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Striatin PF08232.12 KDO31219.1 - 0.12 13.0 16.0 0.44 11.1 15.9 2.1 1 1 0 1 1 1 0 Striatin family Sec8_exocyst PF04048.14 KDO31219.1 - 0.39 10.6 5.4 0.19 11.6 0.6 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain CENP-H PF05837.12 KDO31219.1 - 4.3 7.8 17.0 3.4 8.1 6.2 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 KDO31219.1 - 5.5 7.2 18.5 3.1 8.0 15.8 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Ank_3 PF13606.6 KDO31220.1 - 1.4e-32 108.0 3.5 5.7e-06 26.3 0.0 8.2 6 1 1 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 KDO31220.1 - 9.2e-31 106.3 1.2 2.8e-09 37.4 0.0 6.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31220.1 - 9.1e-29 99.5 2.7 2.2e-13 50.4 0.0 6.1 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO31220.1 - 7.9e-26 89.3 10.4 2.7e-05 24.4 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat TIR_2 PF13676.6 KDO31220.1 - 7.1e-23 81.5 0.0 2.6e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 TIR domain Ank_5 PF13857.6 KDO31220.1 - 2.7e-20 72.1 7.9 3.6e-08 33.5 0.0 7.1 4 1 1 6 6 6 4 Ankyrin repeats (many copies) TIR PF01582.20 KDO31220.1 - 0.00015 21.7 0.0 0.0011 18.8 0.0 2.3 3 0 0 3 3 3 1 TIR domain DUF1863 PF08937.11 KDO31220.1 - 0.16 12.3 0.2 0.92 9.8 0.1 2.3 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) GRDP-like PF07173.12 KDO31221.1 - 5e-17 62.9 4.3 5.5e-17 62.8 0.1 2.5 2 1 0 2 2 2 1 Glycine-rich domain-containing protein-like IBR PF01485.21 KDO31221.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Peptidase_A22B PF04258.13 KDO31222.1 - 2e-65 221.2 3.7 2.6e-65 220.7 3.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KDO31222.1 - 1.5e-05 24.9 1.8 2.7e-05 24.1 0.0 2.3 3 0 0 3 3 3 1 PA domain CTP_transf_like PF01467.26 KDO31223.1 - 6.3e-05 23.2 0.5 0.00022 21.5 0.5 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KDO31223.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase MEA1 PF06910.11 KDO31224.1 - 0.0027 18.3 1.6 0.0034 18.0 1.6 1.2 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) zf-CSL PF05207.13 KDO31225.1 - 7e-19 67.3 2.3 1.3e-18 66.4 2.3 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KDO31225.1 - 6e-18 64.7 0.7 8.2e-18 64.3 0.7 1.2 1 0 0 1 1 1 1 DnaJ domain ATP-synt_S1 PF05827.12 KDO31226.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Snf7 PF03357.21 KDO31227.1 - 2.1e-39 134.9 21.2 2.6e-39 134.6 21.2 1.1 1 0 0 1 1 1 1 Snf7 z-alpha PF02295.17 KDO31227.1 - 0.047 13.7 0.4 0.047 13.7 0.4 2.3 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain DUF4047 PF13256.6 KDO31227.1 - 0.34 11.1 13.1 0.99 9.6 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) YlqD PF11068.8 KDO31227.1 - 0.82 10.0 19.1 0.44 10.9 6.9 2.2 1 1 1 2 2 2 0 YlqD protein Mob1_phocein PF03637.17 KDO31228.1 - 1.9e-32 112.6 4.0 2.4e-32 112.3 4.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Bac_rhamnosid6H PF17389.2 KDO31228.1 - 0.045 13.0 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain WD40 PF00400.32 KDO31229.1 - 4.4e-23 81.1 6.6 2.6e-05 24.9 0.2 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31229.1 - 1.9e-14 53.7 0.0 0.0065 16.8 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO31229.1 - 7.3e-05 21.6 0.0 0.066 11.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KDO31229.1 - 0.00036 20.2 0.1 0.22 11.1 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain RRM_1 PF00076.22 KDO31230.1 - 2.3e-08 33.7 0.0 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KDO31231.1 - 3.3e-43 148.0 0.0 4.3e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31231.1 - 2.3e-18 66.4 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OPA3 PF07047.12 KDO31232.1 - 2e-24 85.8 0.1 3.3e-23 81.8 0.1 2.1 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SlyX PF04102.12 KDO31232.1 - 0.035 14.7 0.1 0.094 13.4 0.1 1.7 2 0 0 2 2 2 0 SlyX WD40 PF00400.32 KDO31233.1 - 1.5e-15 57.3 1.9 2.1e-05 25.2 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31233.1 - 0.0018 18.5 0.0 0.019 15.3 0.0 2.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4365 PF14280.6 KDO31233.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4365) His_Phos_1 PF00300.22 KDO31234.1 - 5.4e-35 120.9 0.0 7.8e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Piwi PF02171.17 KDO31234.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Piwi domain Saf_2TM PF18303.1 KDO31234.1 - 0.04 13.5 0.3 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain HMGL-like PF00682.19 KDO31235.1 - 8.2e-63 212.4 0.0 9.4e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 HMGL-like DUF21 PF01595.20 KDO31236.1 - 4.1e-26 91.8 4.9 6.3e-26 91.1 4.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO31236.1 - 0.05 14.1 0.3 21 5.6 0.0 3.2 2 1 0 2 2 2 0 CBS domain Lum_binding PF00677.17 KDO31237.1 - 1.3e-44 150.1 1.1 1.9e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Adaptin_N PF01602.20 KDO31239.1 - 6.5e-87 292.3 2.1 8.3e-87 291.9 2.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KDO31239.1 - 1.6e-46 158.3 5.7 2.8e-45 154.2 0.4 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KDO31239.1 - 7.8e-17 61.4 0.0 7.4e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KDO31239.1 - 4e-10 40.0 0.4 0.14 12.6 0.0 4.8 2 2 2 4 4 4 4 HEAT repeats Arm_2 PF04826.13 KDO31239.1 - 5.2e-06 26.1 4.9 0.00017 21.1 0.2 2.7 2 1 0 3 3 3 2 Armadillo-like HEAT PF02985.22 KDO31239.1 - 8.4e-05 22.5 3.5 5.2 7.6 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.23 KDO31239.1 - 0.0026 17.7 0.0 0.036 14.1 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KDO31239.1 - 0.044 14.0 0.7 1.1 9.5 0.0 3.5 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2278 PF10042.9 KDO31239.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) mRNA_stabil PF13929.6 KDO31239.1 - 0.11 11.5 0.1 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 mRNA stabilisation DUF5421 PF17458.2 KDO31239.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Popeye PF04831.13 KDO31239.1 - 0.14 12.3 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Popeye protein conserved region SRP_SPB PF02978.19 KDO31240.1 - 2.4e-09 37.7 0.8 3.2e-09 37.3 0.1 1.5 2 0 0 2 2 2 1 Signal peptide binding domain RVT_1 PF00078.27 KDO31240.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WSD PF15613.6 KDO31240.1 - 0.21 12.1 1.7 0.4 11.2 1.7 1.8 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Trigger_C PF05698.14 KDO31240.1 - 0.7 9.9 4.5 7.5 6.5 0.0 2.5 2 1 1 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus PhoLip_ATPase_C PF16212.5 KDO31241.1 - 1.6e-60 204.9 19.9 1.6e-60 204.9 19.9 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO31241.1 - 9.3e-19 66.9 0.3 9.3e-19 66.9 0.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO31241.1 - 3.2e-10 40.7 0.7 0.005 17.1 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO31241.1 - 3.3e-10 39.9 0.0 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO31241.1 - 8.9e-08 31.9 0.0 2.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO31241.1 - 4.9e-05 23.2 0.1 9.9e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FKBP_C PF00254.28 KDO31242.1 - 3.5e-54 181.1 0.0 7.9e-33 112.7 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TM_helix PF05552.12 KDO31243.1 - 0.026 14.5 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 Conserved TM helix DUF2439 PF10382.9 KDO31244.1 - 1.3e-12 47.9 0.0 2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) OTCace_N PF02729.21 KDO31245.1 - 4e-45 153.4 0.2 6.4e-45 152.8 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KDO31245.1 - 1e-40 139.4 0.0 4.5e-40 137.3 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OCD_Mu_crystall PF02423.15 KDO31245.1 - 0.037 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DSS1_SEM1 PF05160.13 KDO31246.1 - 2.1e-17 62.9 15.3 2.4e-17 62.7 15.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Ribosomal_S21 PF01165.20 KDO31248.1 - 1.4e-08 34.3 2.8 2.4e-08 33.6 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 baeRF_family10 PF18854.1 KDO31248.1 - 0.005 17.1 1.1 0.0058 16.9 1.1 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 YscO-like PF16789.5 KDO31248.1 - 0.013 15.5 2.8 0.016 15.3 2.8 1.1 1 0 0 1 1 1 0 YscO-like protein Flavi_capsid PF01003.19 KDO31248.1 - 0.03 14.1 2.0 0.037 13.8 2.0 1.2 1 0 0 1 1 1 0 Flavivirus capsid protein C ANAPC15 PF15243.6 KDO31248.1 - 0.084 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DHC_N1 PF08385.12 KDO31249.1 - 1.9e-188 627.7 2.3 1.9e-188 627.7 2.3 3.7 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KDO31249.1 - 1.6e-124 415.2 10.9 8.1e-124 412.8 1.5 5.1 4 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO31249.1 - 8.3e-112 374.2 18.2 8.3e-112 374.2 18.2 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO31249.1 - 1.1e-95 319.8 0.0 2.1e-92 309.1 0.0 3.2 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KDO31249.1 - 2.3e-79 265.6 2.9 2.3e-79 265.6 2.9 3.6 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 KDO31249.1 - 7.6e-70 235.6 0.7 6.7e-68 229.2 0.7 3.3 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KDO31249.1 - 1.3e-65 220.3 1.1 2.3e-59 200.0 0.2 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KDO31249.1 - 1.3e-53 182.3 12.2 1.3e-53 182.3 12.2 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KDO31249.1 - 3.8e-44 150.4 0.0 1.3e-43 148.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO31249.1 - 4.6e-39 133.2 0.0 4.6e-37 126.7 0.0 4.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KDO31249.1 - 1.4e-25 89.8 0.2 5.9e-25 87.8 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO31249.1 - 6.5e-23 80.8 0.1 2.8e-22 78.8 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO31249.1 - 1.2e-21 77.1 1.3 3.9e-08 33.4 0.0 6.2 6 2 0 6 6 4 3 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KDO31249.1 - 3.4e-07 30.7 2.3 0.004 17.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KDO31249.1 - 3.5e-07 30.1 0.9 0.02 14.6 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KDO31249.1 - 4.6e-07 30.3 0.8 0.11 13.0 0.0 5.3 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO31249.1 - 2.2e-06 28.2 0.1 0.069 13.7 0.0 5.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 KDO31249.1 - 3.5e-06 27.5 4.3 0.0017 18.8 0.0 5.4 5 0 0 5 5 4 1 AAA ATPase domain T2SSE PF00437.20 KDO31249.1 - 6.5e-06 25.4 2.4 0.052 12.6 0.1 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_22 PF13401.6 KDO31249.1 - 0.00012 22.4 0.3 0.41 10.9 0.0 4.9 4 1 0 4 4 4 1 AAA domain NACHT PF05729.12 KDO31249.1 - 0.00016 21.6 0.3 0.19 11.6 0.0 3.6 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 KDO31249.1 - 0.0015 18.9 0.3 4.8 7.6 0.0 4.1 3 0 0 3 3 3 1 RNA helicase Sigma54_activ_2 PF14532.6 KDO31249.1 - 0.0022 18.1 0.0 0.32 11.1 0.0 3.5 3 0 0 3 3 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KDO31249.1 - 0.0024 18.4 0.2 0.098 13.2 0.0 3.8 3 0 0 3 3 3 1 ABC transporter SRP54 PF00448.22 KDO31249.1 - 0.0032 17.1 3.3 0.76 9.4 0.1 4.1 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain TsaE PF02367.17 KDO31249.1 - 0.0037 17.2 0.3 1.3 9.0 0.0 3.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KDO31249.1 - 0.0042 17.4 0.1 10 6.3 0.0 4.1 3 0 0 3 3 3 0 AAA domain BCDHK_Adom3 PF10436.9 KDO31249.1 - 0.012 15.5 1.4 0.1 12.4 0.1 3.3 3 0 0 3 3 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Sigma54_activat PF00158.26 KDO31249.1 - 0.021 14.5 0.1 13 5.4 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KDO31249.1 - 0.046 13.4 4.3 4.1 7.1 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 KDO31249.1 - 0.049 13.8 0.5 5.7 7.1 0.0 4.1 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 KDO31249.1 - 0.059 12.9 0.6 23 4.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KDO31249.1 - 0.072 13.1 0.0 0.78 9.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 KDO31249.1 - 0.081 12.7 0.5 55 3.4 0.0 4.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 KDO31249.1 - 1.7 7.9 5.2 3.9 6.8 0.0 3.8 4 0 0 4 4 4 0 KaiC Roc PF08477.13 KDO31249.1 - 2.4 8.4 8.3 0.37 11.0 0.0 4.0 5 0 0 5 5 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4164 PF13747.6 KDO31249.1 - 6.3 7.1 14.7 0.49 10.7 4.6 4.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) Ank_2 PF12796.7 KDO31250.1 - 1e-29 102.9 25.6 1.2e-06 29.0 0.1 7.0 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31250.1 - 3.6e-27 94.4 24.5 6.3e-05 23.4 0.2 9.7 4 4 6 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31250.1 - 1.5e-20 73.0 29.8 0.02 15.2 0.1 12.6 4 4 10 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31250.1 - 6.4e-14 50.7 14.7 0.53 11.0 0.2 13.1 12 3 3 15 15 15 1 Ankyrin repeat DUF3322 PF11795.8 KDO31250.1 - 0.002 18.2 4.7 0.49 10.4 0.1 4.6 2 2 3 5 5 5 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) HA PF03457.14 KDO31250.1 - 0.016 15.5 0.0 2.1 8.8 0.0 3.8 3 2 1 4 4 4 0 Helicase associated domain NCBP3 PF10309.9 KDO31250.1 - 0.12 12.3 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 Ank PF00023.30 KDO31250.1 - 0.62 10.6 33.8 35 5.1 0.6 9.6 4 2 0 4 4 4 0 Ankyrin repeat MEA1 PF06910.11 KDO31251.1 - 0.0014 19.3 1.3 0.0019 18.8 1.3 1.2 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Ribosomal_L1 PF00687.21 KDO31252.1 - 5.2e-34 117.8 3.6 6.5e-34 117.5 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MDD_C PF18376.1 KDO31253.1 - 3.7e-65 219.2 0.6 7.7e-65 218.1 0.6 1.5 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KDO31253.1 - 1.5e-06 28.3 1.3 4e-06 27.0 1.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain 2-oxoacid_dh PF00198.23 KDO31254.1 - 4e-78 262.1 0.4 1e-77 260.7 0.4 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KDO31254.1 - 6.3e-38 128.5 11.5 1.2e-18 66.7 2.7 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_D23 PF16576.5 KDO31254.1 - 0.031 13.5 0.7 12 5.1 0.0 3.2 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3597 PF12200.8 KDO31254.1 - 0.079 13.5 6.7 1.8 9.1 0.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Hexokinase_1 PF00349.21 KDO31254.1 - 0.082 12.8 0.2 8.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Hexokinase GCV_H PF01597.19 KDO31254.1 - 0.23 11.3 5.9 1.2 9.0 0.6 2.6 2 1 0 2 2 2 0 Glycine cleavage H-protein HlyD_3 PF13437.6 KDO31254.1 - 0.6 10.8 14.6 0.16 12.7 0.9 3.9 2 2 2 4 4 4 0 HlyD family secretion protein Glyco_hydro_79C PF16862.5 KDO31254.1 - 0.73 10.8 3.5 14 6.6 0.3 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain PYNP_C PF07831.13 KDO31254.1 - 0.84 9.3 3.3 6.1 6.6 0.1 3.1 2 1 1 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain Herpes_UL4 PF03277.13 KDO31254.1 - 9.8 5.7 6.5 2.6 7.6 1.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL4 family Biotin_lipoyl PF00364.22 KDO31256.1 - 9.9e-37 124.6 1.0 3.7e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 KDO31256.1 - 3.5e-05 24.5 9.2 0.023 15.4 0.2 3.9 3 2 2 5 5 5 3 HlyD family secretion protein GCV_H PF01597.19 KDO31256.1 - 7e-05 22.7 1.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 KDO31256.1 - 7.1e-05 22.6 8.9 0.92 9.4 0.0 4.1 2 2 2 4 4 4 3 Biotin-lipoyl like RnfC_N PF13375.6 KDO31256.1 - 0.04 13.9 1.2 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KDO31256.1 - 0.069 12.4 0.2 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion bZIP_1 PF00170.21 KDO31257.1 - 0.0004 20.4 1.6 0.00075 19.6 1.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO31257.1 - 0.00078 19.5 3.2 0.0013 18.8 3.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KDO31257.1 - 0.038 14.5 3.6 0.085 13.4 3.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor ZapB PF06005.12 KDO31257.1 - 0.12 12.8 0.5 0.24 11.9 0.2 1.6 1 1 0 1 1 1 0 Cell division protein ZapB NPV_P10 PF05531.12 KDO31257.1 - 0.15 12.6 0.3 2.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tub PF01167.18 KDO31258.1 - 1.6e-50 172.1 0.1 4.7e-50 170.6 0.1 1.7 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.8 KDO31258.1 - 0.0042 16.7 0.1 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) Ank_4 PF13637.6 KDO31259.1 - 1.1e-16 61.0 4.7 7.8e-06 26.3 0.8 3.9 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31259.1 - 5.1e-16 59.0 7.2 1.3e-08 35.3 5.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31259.1 - 7.9e-13 47.4 4.1 0.2 12.3 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO31259.1 - 1.2e-12 47.7 7.7 0.00025 21.3 1.6 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO31259.1 - 0.00011 22.5 4.8 5.1 7.7 0.2 5.0 5 0 0 5 5 5 2 Ankyrin repeat VPS53_C PF16854.5 KDO31259.1 - 0.015 15.1 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus EH_Signature PF15611.6 KDO31259.1 - 0.044 13.2 0.1 0.13 11.7 0.1 1.7 1 1 1 2 2 2 0 EH_Signature domain HMG_box_2 PF09011.10 KDO31261.1 - 5.6e-05 23.6 0.5 0.00019 21.9 0.5 2.0 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KDO31261.1 - 0.0055 17.1 2.9 0.062 13.7 2.9 2.7 1 1 0 1 1 1 1 HMG (high mobility group) box Kinesin PF00225.23 KDO31262.1 - 2.7e-95 319.1 5.7 2.7e-95 319.1 5.7 2.6 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KDO31262.1 - 8.7e-24 84.1 0.6 2.9e-23 82.5 0.1 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_lid_4 PF17864.1 KDO31262.1 - 0.0098 15.6 0.1 0.038 13.8 0.1 2.0 1 0 0 1 1 1 1 RuvB AAA lid domain DUF496 PF04363.12 KDO31262.1 - 0.04 14.0 3.7 1.3 9.2 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF496) HDV_ag PF01517.18 KDO31262.1 - 0.25 11.1 3.1 0.15 11.9 0.6 1.8 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Phosphoesterase PF04185.14 KDO31263.1 - 0.033 13.4 2.5 0.039 13.1 2.5 1.1 1 0 0 1 1 1 0 Phosphoesterase family Hydrolase PF00702.26 KDO31264.1 - 4.1e-14 53.4 0.1 7.2e-14 52.6 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO31264.1 - 8.4e-14 52.4 0.1 3.6e-13 50.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KDO31264.1 - 5.1e-05 22.8 0.0 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 KDO31264.1 - 0.0052 16.3 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 KDO31264.1 - 0.045 13.8 0.0 7.2 6.7 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase StbA PF06406.11 KDO31264.1 - 0.17 11.1 0.0 0.71 9.0 0.0 1.8 2 0 0 2 2 2 0 StbA protein Peptidase_M1 PF01433.20 KDO31265.1 - 7.5e-84 280.7 3.5 1.3e-83 279.9 3.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KDO31265.1 - 9e-55 186.4 0.1 1.8e-53 182.1 0.2 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KDO31265.1 - 7.7e-40 137.1 0.0 2.2e-39 135.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KDO31265.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) FapA PF03961.13 KDO31266.1 - 0.032 12.9 0.1 0.043 12.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_1 PF00170.21 KDO31266.1 - 0.068 13.3 5.9 0.15 12.2 5.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor PEARLI-4 PF05278.12 KDO31266.1 - 0.097 12.3 1.9 0.15 11.7 1.9 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) bZIP_2 PF07716.15 KDO31268.1 - 7.8e-06 25.9 1.8 1.4e-05 25.0 1.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO31268.1 - 2e-05 24.6 0.6 4e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4618 PF15397.6 KDO31268.1 - 0.0088 15.5 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 KDO31268.1 - 0.049 13.9 0.1 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Trimer_CC PF08954.11 KDO31268.1 - 1.9 8.1 6.4 1.3 8.7 4.2 1.8 1 1 1 2 2 2 0 Trimerisation motif bZIP_2 PF07716.15 KDO31269.1 - 0.0097 16.0 1.4 0.019 15.0 1.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO31270.1 - 0.17 12.0 5.2 0.29 11.2 5.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KDO31271.1 - 0.00033 20.7 2.0 0.00052 20.0 2.0 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO31271.1 - 0.014 15.5 1.4 0.021 14.9 1.4 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KDO31272.1 - 0.00025 21.0 1.2 0.00037 20.5 0.5 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO31272.1 - 0.0019 18.2 5.6 0.0041 17.2 5.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Hydantoinase_B PF02538.14 KDO31273.1 - 0.047 12.1 0.0 0.064 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Olfactory_mark PF06554.12 KDO31273.1 - 0.13 12.1 0.0 0.26 11.0 0.0 1.5 2 0 0 2 2 2 0 Olfactory marker protein DUF4252 PF14060.6 KDO31273.1 - 0.17 11.7 0.0 0.66 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) bZIP_2 PF07716.15 KDO31274.1 - 0.00066 19.7 1.5 0.00094 19.2 0.7 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO31274.1 - 0.019 15.0 5.4 0.041 14.0 5.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor zf-DNA_Pol PF08996.10 KDO31274.1 - 0.077 12.7 0.4 0.21 11.3 0.4 1.7 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger SepSecS PF05889.13 KDO31276.1 - 2.5e-89 299.7 0.0 2.4e-82 276.7 0.0 2.2 2 0 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KDO31276.1 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KDO31276.1 - 0.054 12.2 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CLU PF13236.6 KDO31277.1 - 2.4e-73 246.6 0.0 4.6e-73 245.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KDO31277.1 - 6.4e-33 114.2 0.1 2.4e-32 112.4 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KDO31277.1 - 3.7e-14 52.8 21.2 6.3e-06 26.4 0.8 4.6 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO31277.1 - 1.8e-07 30.8 6.4 0.002 18.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31277.1 - 0.16 12.2 6.1 26 5.2 0.6 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO31277.1 - 0.61 10.2 3.8 1.9 8.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Bmt2 PF11968.8 KDO31278.1 - 3.6e-52 177.4 0.0 4.5e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KDO31278.1 - 1.2e-07 31.7 0.0 9.8e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO31278.1 - 4.6e-06 27.2 0.0 1.4e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO31278.1 - 3.2e-05 24.6 0.0 0.00017 22.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO31278.1 - 9.7e-05 23.0 0.0 0.00027 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KDO31278.1 - 0.00057 19.8 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 KDO31278.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TyeA PF09059.10 KDO31278.1 - 0.081 13.0 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 TyeA DUF4208 PF13907.6 KDO31278.1 - 0.12 12.8 0.1 0.58 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) LRR_8 PF13855.6 KDO31279.1 - 6.4e-06 25.8 1.5 1.5e-05 24.6 1.4 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KDO31279.1 - 0.0033 17.8 3.9 0.43 11.1 0.3 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Phage_holin_7_1 PF16081.5 KDO31279.1 - 0.15 12.2 0.9 0.23 11.6 0.1 1.7 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family LRR_4 PF12799.7 KDO31280.1 - 0.0042 17.5 1.1 0.11 13.0 0.3 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 KDO31281.1 - 4.3e-19 68.8 0.0 7.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31281.1 - 2.7e-17 63.0 0.0 4.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 KDO31281.1 - 0.058 13.5 0.7 18 5.7 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat DUF347 PF03988.12 KDO31281.1 - 0.1 12.8 0.6 0.24 11.6 0.6 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) LRR_1 PF00560.33 KDO31281.1 - 0.51 11.1 2.8 21 6.2 0.1 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat START PF01852.19 KDO31282.1 - 2.1e-05 24.0 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 KDO31282.1 - 0.00083 19.4 10.2 0.0017 18.4 10.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger ArfGap PF01412.18 KDO31282.1 - 1.1 9.4 5.4 2.5 8.2 5.4 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DA1-like PF12315.8 KDO31283.1 - 1.8e-34 119.0 0.0 1.4e-32 112.8 0.0 2.3 1 1 0 1 1 1 1 Protein DA1 LIM PF00412.22 KDO31283.1 - 4.1e-12 46.1 2.1 4.1e-12 46.1 2.1 3.8 2 1 1 4 4 4 2 LIM domain zf-RanBP PF00641.18 KDO31283.1 - 3.8e-08 32.5 1.0 3.8e-08 32.5 1.0 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DZR PF12773.7 KDO31283.1 - 2.8 8.0 28.7 1.8e+04 -9.4 28.7 4.3 1 1 0 1 1 1 0 Double zinc ribbon CHAP PF05257.16 KDO31284.1 - 4.1e-15 56.1 0.3 7.6e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 CHAP domain Tyrosinase PF00264.20 KDO31285.1 - 2.5e-26 93.3 0.1 7e-26 91.9 0.1 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase Haem_oxygenas_2 PF14518.6 KDO31285.1 - 0.046 13.5 0.2 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Iron-containing redox enzyme Na_H_Exchanger PF00999.21 KDO31286.1 - 4.1e-58 197.0 24.5 5e-58 196.7 24.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_C PF07664.12 KDO31286.1 - 0.016 14.9 0.4 0.38 10.5 0.1 3.1 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Pkinase PF00069.25 KDO31287.1 - 9e-58 195.7 0.0 1.1e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31287.1 - 1.3e-25 90.2 0.0 1.5e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO31287.1 - 7.8e-10 39.1 3.5 2.6e-06 27.6 0.9 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO31287.1 - 3.9e-06 26.4 0.0 7.7e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO31287.1 - 6.4e-06 25.9 0.3 1e-05 25.2 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KDO31287.1 - 1.2e-05 24.7 0.3 1.9e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO31287.1 - 0.00018 21.1 0.4 0.00062 19.4 0.4 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 KDO31287.1 - 0.0097 15.5 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.11 KDO31287.1 - 0.04 13.0 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 KDO31287.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pox_ser-thr_kin PF05445.11 KDO31287.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_17 PF13431.6 KDO31288.1 - 1.1e-20 72.4 4.8 0.0038 17.5 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31288.1 - 1e-12 47.2 4.7 5.3 7.5 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31288.1 - 1.4e-12 47.3 27.1 0.16 12.9 0.1 9.0 3 2 7 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31288.1 - 1.1e-09 37.6 15.7 4.9 7.5 0.1 9.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO31288.1 - 2e-06 28.2 20.6 0.034 14.7 1.5 5.6 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KDO31288.1 - 1.3e-05 24.8 4.8 14 5.5 0.0 6.6 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.6 KDO31288.1 - 5.7e-05 23.3 28.1 0.33 11.3 0.3 6.5 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31288.1 - 6.9e-05 22.5 13.5 4.7 7.2 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31288.1 - 0.00061 20.4 31.1 0.0043 17.7 0.5 5.4 5 2 0 5 5 5 3 Tetratricopeptide repeat End_beta_propel PF12217.8 KDO31288.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase TPR_7 PF13176.6 KDO31288.1 - 0.26 11.4 17.5 1.3 9.2 0.0 7.4 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO31288.1 - 1.5 8.8 18.3 2.1 8.3 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DivIC PF04977.15 KDO31289.1 - 0.0071 16.1 0.9 0.012 15.4 0.9 1.4 1 0 0 1 1 1 1 Septum formation initiator FlaC_arch PF05377.11 KDO31289.1 - 0.027 14.9 1.5 0.11 12.9 0.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Erf4 PF10256.9 KDO31289.1 - 0.034 14.2 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ZapB PF06005.12 KDO31289.1 - 0.25 11.8 12.1 0.48 10.9 12.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Prefoldin_2 PF01920.20 KDO31290.1 - 1.9e-18 66.4 5.6 1.9e-18 66.4 5.6 1.7 2 0 0 2 2 1 1 Prefoldin subunit TPR_1 PF00515.28 KDO31290.1 - 2.1e-14 52.7 6.4 2.2e-07 30.4 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31290.1 - 1e-11 44.0 6.2 4.4e-05 23.3 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31290.1 - 5.9e-06 26.1 5.9 0.14 12.4 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO31290.1 - 1.4e-05 24.6 7.6 0.00011 21.9 2.6 3.2 1 1 2 3 3 3 1 TPR repeat TPR_17 PF13431.6 KDO31290.1 - 0.00059 20.0 4.6 0.37 11.3 0.2 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31290.1 - 0.00075 20.1 3.9 1.3 10.1 0.0 4.1 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO31290.1 - 0.00077 19.7 0.3 0.00077 19.7 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF5320 PF17253.2 KDO31290.1 - 0.0015 19.6 2.2 1.4 10.0 0.2 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5320) TPR_6 PF13174.6 KDO31290.1 - 0.0019 18.7 1.5 1.4 9.7 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31290.1 - 0.002 18.8 5.7 0.057 14.1 0.1 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO31290.1 - 0.0021 18.5 7.1 0.045 14.3 0.4 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat DHR10 PF18595.1 KDO31290.1 - 0.0032 17.5 12.4 1.8 8.7 0.0 3.3 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain TPR_7 PF13176.6 KDO31290.1 - 0.0055 16.6 0.9 1 9.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat CENP-F_leu_zip PF10473.9 KDO31290.1 - 0.0061 16.6 8.0 0.03 14.3 1.0 2.5 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_10 PF13374.6 KDO31290.1 - 0.011 15.6 13.6 0.33 10.9 0.3 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat GAS PF13851.6 KDO31290.1 - 0.015 14.6 8.1 0.067 12.5 0.6 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Dad2 PF08654.10 KDO31290.1 - 0.02 15.3 2.9 0.98 9.9 0.0 3.1 2 1 0 3 3 3 0 DASH complex subunit Dad2 DUF812 PF05667.11 KDO31290.1 - 0.022 13.7 7.5 0.024 13.6 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CLZ PF16526.5 KDO31290.1 - 0.042 14.2 5.3 2.4 8.6 0.1 3.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 KDO31290.1 - 0.053 13.8 4.4 2.1 8.7 0.4 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KDO31290.1 - 0.056 13.5 4.4 1.9 8.5 4.4 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 KDO31290.1 - 0.058 13.6 7.2 3.1 8.0 0.3 2.7 2 0 0 2 2 2 0 Tropomyosin like Lectin_N PF03954.14 KDO31290.1 - 0.058 13.1 4.7 1.2 8.8 4.7 2.3 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain PspB PF06667.12 KDO31290.1 - 0.064 13.3 2.7 3 7.9 0.2 2.7 2 1 0 2 2 2 0 Phage shock protein B Jnk-SapK_ap_N PF09744.9 KDO31290.1 - 0.075 13.3 12.1 0.2 11.9 1.6 2.8 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 KDO31290.1 - 0.088 12.9 6.6 0.16 12.1 6.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HSBP1 PF06825.12 KDO31290.1 - 0.089 12.7 0.2 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF4140 PF13600.6 KDO31290.1 - 0.09 13.2 8.3 2 8.9 0.6 2.7 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SKA2 PF16740.5 KDO31290.1 - 0.11 12.3 8.0 0.49 10.2 1.7 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 KDO31290.1 - 0.11 12.7 4.7 0.043 14.0 2.1 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 KDO31290.1 - 0.11 12.5 4.9 4.3 7.4 0.2 2.6 2 0 0 2 2 2 0 FlxA-like protein Fungal_TACC PF12709.7 KDO31290.1 - 0.15 12.5 4.7 0.23 11.9 0.7 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 KDO31290.1 - 0.16 10.8 9.2 0.49 9.2 9.2 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KDO31290.1 - 0.17 10.5 4.8 0.48 9.0 4.2 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A YabA PF06156.13 KDO31290.1 - 0.24 12.0 7.1 0.89 10.2 1.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 KDO31290.1 - 0.28 11.2 1.5 26 4.8 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KDO31290.1 - 0.3 11.2 10.6 0.59 10.2 3.6 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 KDO31290.1 - 0.35 10.8 10.3 34 4.4 10.3 2.5 1 1 0 1 1 1 0 Prefoldin subunit SesA PF17107.5 KDO31290.1 - 0.35 11.0 5.7 2 8.6 0.3 2.8 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3450 PF11932.8 KDO31290.1 - 0.36 10.1 10.1 1.9 7.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 KDO31290.1 - 0.41 10.6 7.9 2.2 8.2 1.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain WXG100 PF06013.12 KDO31290.1 - 0.41 10.9 8.1 1.3 9.3 0.1 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Tektin PF03148.14 KDO31290.1 - 0.45 9.2 10.3 1 8.1 1.6 2.5 3 0 0 3 3 3 0 Tektin family TPR_MLP1_2 PF07926.12 KDO31290.1 - 0.46 10.6 13.8 0.62 10.1 2.9 2.9 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KDO31290.1 - 0.49 10.9 2.5 11 6.6 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KDO31290.1 - 0.64 10.3 7.2 2.7 8.3 1.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) Sec34 PF04136.15 KDO31290.1 - 0.66 9.9 5.6 12 5.7 1.6 2.4 2 0 0 2 2 2 0 Sec34-like family GIT_CC PF16559.5 KDO31290.1 - 0.7 9.8 6.5 7 6.6 0.2 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3847 PF12958.7 KDO31290.1 - 0.76 9.9 6.9 5.2 7.3 0.6 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3847) COG2 PF06148.11 KDO31290.1 - 0.92 9.6 4.4 1.5 8.9 0.1 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 KDO31290.1 - 1.5 9.1 8.8 12 6.1 1.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.11 KDO31290.1 - 1.7 8.9 8.3 7.4 6.9 0.6 2.6 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 KDO31290.1 - 2.8 8.1 14.6 1.4 9.1 1.2 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase ABC_tran_CTD PF16326.5 KDO31290.1 - 3.1 8.1 13.1 0.39 11.0 1.0 3.2 3 1 0 3 3 2 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 KDO31290.1 - 4 7.6 13.8 10 6.3 0.6 4.2 3 1 1 4 4 4 0 Basic region leucine zipper Nsp1_C PF05064.13 KDO31290.1 - 4.4 7.2 8.7 1.9 8.3 0.7 2.7 3 0 0 3 3 2 0 Nsp1-like C-terminal region APG6_N PF17675.1 KDO31290.1 - 5.1 7.6 16.4 11 6.6 5.7 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region PikAIV_N PF18605.1 KDO31291.1 - 0.00079 19.0 7.3 0.092 12.3 0.6 2.5 2 0 0 2 2 2 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 KDO31291.1 - 0.0026 18.1 6.3 0.023 15.1 6.0 2.3 1 1 0 1 1 1 1 Cell division protein ZapB HTH_7 PF02796.15 KDO31291.1 - 0.093 12.8 0.2 4.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DivIC PF04977.15 KDO31291.1 - 0.2 11.4 7.7 0.26 11.1 1.6 2.8 2 1 1 3 3 3 0 Septum formation initiator HALZ PF02183.18 KDO31291.1 - 1.3 9.3 6.1 14 6.0 0.7 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper GIT_CC PF16559.5 KDO31291.1 - 3.3 7.6 5.7 7.8 6.5 1.4 2.7 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor NRBF2 PF08961.10 KDO31291.1 - 8.1 6.0 7.5 3.4 7.2 2.2 2.3 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator HTH_32 PF13565.6 KDO31291.1 - 8.2 7.1 7.7 12 6.6 0.8 3.1 1 1 3 4 4 4 0 Homeodomain-like domain MFS_2 PF13347.6 KDO31292.1 - 2.3e-07 29.8 6.8 2.3e-07 29.8 6.8 2.5 2 1 0 3 3 3 1 MFS/sugar transport protein Peptidase_M41 PF01434.18 KDO31293.1 - 1e-62 211.4 0.4 5.9e-62 208.9 0.1 2.1 1 1 1 2 2 2 1 Peptidase family M41 AAA PF00004.29 KDO31293.1 - 2.6e-42 144.4 0.0 5.7e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO31293.1 - 3.9e-15 55.4 0.1 1e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KDO31293.1 - 6.1e-06 26.6 0.0 2.4e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 KDO31293.1 - 0.00015 22.1 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KDO31293.1 - 0.00029 20.9 0.5 0.008 16.2 0.1 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KDO31293.1 - 0.004 16.4 1.6 0.0047 16.2 0.1 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 KDO31293.1 - 0.0042 17.2 0.4 0.016 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KDO31293.1 - 0.0046 16.4 0.0 0.013 14.9 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KDO31293.1 - 0.0074 16.7 0.1 0.13 12.6 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO31293.1 - 0.0078 16.0 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KDO31293.1 - 0.0097 15.7 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KDO31293.1 - 0.01 15.4 0.0 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 KDO31293.1 - 0.015 14.2 0.0 0.036 13.0 0.0 1.5 1 0 0 1 1 1 0 PrkA AAA domain AAA_14 PF13173.6 KDO31293.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO31293.1 - 0.058 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KDO31293.1 - 0.06 13.8 0.3 0.53 10.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 KDO31293.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) LIME1 PF15332.6 KDO31293.1 - 0.14 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 PDZ_6 PF17820.1 KDO31294.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain cwf18 PF08315.12 KDO31295.1 - 2.2 8.9 7.3 0.21 12.3 1.3 2.2 2 1 0 2 2 2 0 cwf18 pre-mRNA splicing factor WW PF00397.26 KDO31296.1 - 5.2e-07 29.6 1.2 0.0044 17.1 0.0 3.2 3 0 0 3 3 3 2 WW domain JAKMIP_CC3 PF16034.5 KDO31296.1 - 0.018 15.0 3.8 0.045 13.7 3.8 1.7 1 0 0 1 1 1 0 JAKMIP CC3 domain ubiquitin PF00240.23 KDO31297.1 - 0.0041 16.9 0.1 0.01 15.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KDO31297.1 - 0.19 12.3 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain EMC1_C PF07774.13 KDO31298.1 - 1.1e-61 208.2 0.0 2.1e-61 207.3 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KDO31298.1 - 6e-09 35.8 8.5 3.5e-06 26.8 0.1 2.9 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KDO31298.1 - 0.0071 16.2 0.6 0.34 10.9 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat Keratin PF02422.16 KDO31299.1 - 0.027 14.1 0.3 0.046 13.4 0.3 1.3 1 0 0 1 1 1 0 Keratin DUF4505 PF14956.6 KDO31300.1 - 4.2e-38 130.9 0.0 5.8e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) Metallophos PF00149.28 KDO31301.1 - 7e-22 78.9 0.1 2.1e-21 77.4 0.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 KDO31301.1 - 9.9e-13 46.7 0.1 7.7e-07 28.2 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KDO31301.1 - 3.8e-10 38.9 0.6 3.3e-05 23.5 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KDO31301.1 - 2.1e-09 37.7 0.7 0.00035 21.0 0.1 3.0 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO31301.1 - 7.5e-07 28.9 0.5 0.0013 18.6 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO31301.1 - 0.00012 21.3 0.1 0.0069 15.8 0.0 2.8 2 0 0 2 2 2 1 EF hand DUF2613 PF11021.8 KDO31302.1 - 0.044 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TPR_1 PF00515.28 KDO31303.1 - 1.3e-17 62.8 2.4 3e-06 26.8 0.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31303.1 - 8.8e-17 59.8 2.6 1.5e-06 27.8 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31303.1 - 6.2e-11 41.6 2.8 3e-06 27.0 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO31303.1 - 1.4e-08 34.7 2.9 0.0039 17.2 0.3 3.3 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KDO31303.1 - 3e-08 33.8 0.2 5.1e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO31303.1 - 3.1e-08 33.2 2.7 0.0044 16.7 0.7 3.3 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.6 KDO31303.1 - 1.6e-07 30.8 0.1 0.1 12.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31303.1 - 1.6e-07 31.5 0.1 0.0053 17.5 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO31303.1 - 1.8e-07 31.2 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO31303.1 - 7.5e-07 29.4 0.5 0.019 15.6 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO31303.1 - 8.9e-07 29.1 0.8 0.00041 20.5 0.2 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KDO31303.1 - 1e-06 28.7 1.4 0.0063 16.8 0.0 3.6 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO31303.1 - 5.9e-06 26.7 1.1 2.1e-05 24.9 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31303.1 - 9.6e-06 26.2 0.1 0.001 19.7 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Flavodoxin_3 PF12641.7 KDO31303.1 - 0.0036 17.0 0.2 0.0079 15.9 0.2 1.5 1 1 0 1 1 1 1 Flavodoxin domain BTAD PF03704.17 KDO31303.1 - 0.011 16.2 0.2 0.022 15.2 0.2 1.7 1 1 0 1 1 1 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 KDO31303.1 - 0.014 15.9 0.8 0.051 14.0 0.7 2.1 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 KDO31303.1 - 0.056 13.3 0.1 21 5.1 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 KDO31303.1 - 0.065 13.3 1.5 13 5.9 0.2 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain hnRNP_Q_AcD PF18360.1 KDO31303.1 - 0.076 13.0 0.2 25 4.9 0.0 3.1 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF726 PF05277.12 KDO31304.1 - 2.7e-11 43.0 0.8 1.6e-08 33.8 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF726) DUF900 PF05990.12 KDO31304.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 KDO31304.1 - 0.00043 20.9 3.1 0.00061 20.5 0.9 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KDO31304.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.8 KDO31304.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aconitase_B_N PF11791.8 KDO31304.1 - 0.087 12.9 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Aconitate B N-terminal domain LCAT PF02450.15 KDO31304.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase SMC_N PF02463.19 KDO31305.1 - 4.8e-63 212.5 0.0 7.9e-63 211.8 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KDO31305.1 - 3.5e-25 88.6 0.0 1.4e-24 86.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KDO31305.1 - 6e-15 56.3 1.7 6e-15 56.3 1.7 6.3 4 2 1 5 5 5 1 AAA domain AAA_21 PF13304.6 KDO31305.1 - 1.1e-14 55.0 4.1 1.7e-08 34.7 0.1 4.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO31305.1 - 5.7e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KDO31305.1 - 0.00094 19.0 17.9 0.00094 19.0 17.9 3.8 2 2 1 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 KDO31305.1 - 0.058 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DASH_Dam1 PF08653.10 KDO31305.1 - 0.44 10.4 2.6 59 3.6 0.0 4.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF572 PF04502.13 KDO31306.1 - 6.8e-76 256.0 6.0 9.1e-76 255.6 6.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) MRP-S22 PF10245.9 KDO31306.1 - 0.0051 16.6 0.6 0.0051 16.6 0.6 1.4 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S22 zf-FCS PF06467.14 KDO31306.1 - 0.089 12.7 2.1 5 7.2 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif ArsA_ATPase PF02374.15 KDO31307.1 - 2.1e-113 378.5 0.1 2.5e-113 378.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KDO31307.1 - 5.1e-13 49.3 0.0 1.7e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KDO31307.1 - 5.9e-13 49.0 0.0 4.4e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KDO31307.1 - 7e-07 29.0 0.1 0.00057 19.4 0.0 2.3 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ ParA PF10609.9 KDO31307.1 - 1.7e-06 27.7 0.4 0.00064 19.3 0.0 2.6 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KDO31307.1 - 5.3e-06 26.1 0.0 1.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KDO31307.1 - 0.00074 19.2 0.2 0.011 15.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KDO31307.1 - 0.0058 16.2 0.1 0.017 14.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO31307.1 - 0.037 13.7 0.1 0.14 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO31307.1 - 0.041 13.1 0.2 0.13 11.5 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 KDO31307.1 - 0.084 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein MeaB PF03308.16 KDO31307.1 - 0.096 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 KDO31307.1 - 0.11 11.7 0.2 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 VirC1 protein Zeta_toxin PF06414.12 KDO31307.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 KDO31307.1 - 0.17 11.0 0.3 0.9 8.6 0.1 2.0 2 1 0 2 2 2 0 PIF1-like helicase Lipase_3 PF01764.25 KDO31309.1 - 1.5e-05 24.9 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KDO31309.1 - 0.065 12.9 0.4 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 KDO31309.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Methyltransf_25 PF13649.6 KDO31310.1 - 6.9e-07 29.9 0.0 1.3e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO31310.1 - 2.3e-06 28.3 0.0 4.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO31310.1 - 1.7e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO31310.1 - 0.0003 20.4 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KDO31310.1 - 0.00031 21.3 0.1 0.00064 20.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KDO31310.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_5 PF01795.19 KDO31310.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family zf-RING_2 PF13639.6 KDO31311.1 - 3.3e-08 33.7 25.2 6.2e-06 26.4 7.0 4.0 4 0 0 4 4 4 2 Ring finger domain ZZ PF00569.17 KDO31311.1 - 1.7e-07 30.9 13.5 1.7e-07 30.9 13.5 3.3 4 0 0 4 4 4 1 Zinc finger, ZZ type PHD PF00628.29 KDO31311.1 - 0.0001 22.1 8.6 0.0001 22.1 8.6 4.0 3 2 0 3 3 3 1 PHD-finger zf-C3HC4 PF00097.25 KDO31311.1 - 0.00027 20.7 43.6 0.0025 17.7 6.2 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO31311.1 - 0.00036 20.2 3.8 0.00036 20.2 3.8 3.9 4 0 0 4 4 4 2 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO31311.1 - 0.004 17.1 6.6 0.004 17.1 6.6 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KDO31311.1 - 0.12 12.4 47.2 0.085 12.8 9.0 3.7 3 0 0 3 3 3 0 zinc-RING finger domain zf_PR_Knuckle PF18445.1 KDO31311.1 - 0.29 11.0 1.7 0.88 9.4 0.3 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif LRR_6 PF13516.6 KDO31312.1 - 1.2e-23 81.1 27.7 0.0097 15.9 0.0 14.1 15 0 0 15 15 15 6 Leucine Rich repeat LRR_4 PF12799.7 KDO31312.1 - 3e-20 72.0 7.9 0.021 15.3 0.3 10.1 3 2 8 13 13 13 9 Leucine Rich repeats (2 copies) IQ PF00612.27 KDO31312.1 - 4.6e-12 44.6 57.9 0.098 12.5 3.7 9.9 9 0 0 9 9 9 7 IQ calmodulin-binding motif LRR_1 PF00560.33 KDO31312.1 - 8.1e-08 31.8 9.3 26 5.9 0.0 10.8 10 1 0 10 10 10 0 Leucine Rich Repeat zf-B_box PF00643.24 KDO31312.1 - 0.0058 16.8 8.4 0.016 15.4 8.4 1.8 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.21 KDO31312.1 - 0.0094 16.2 4.9 0.032 14.4 4.9 1.9 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain LRR_8 PF13855.6 KDO31312.1 - 0.017 14.9 12.0 2.4 8.0 1.3 6.8 6 3 2 8 8 8 0 Leucine rich repeat Aida_N PF08910.10 KDO31312.1 - 0.13 12.6 1.3 0.41 11.1 1.3 1.8 1 0 0 1 1 1 0 Aida N-terminus CEBP_ZZ PF16366.5 KDO31312.1 - 0.14 12.4 8.7 0.037 14.2 4.8 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KDO31313.1 - 3.4e-68 225.4 5.2 1.6e-18 66.3 0.1 6.7 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO31313.1 - 4.9e-05 22.9 0.1 0.0091 15.6 0.1 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO31313.1 - 0.0005 19.9 0.2 0.91 9.4 0.0 3.7 3 1 0 3 3 3 2 Occluded RNA-recognition motif DbpA PF03880.15 KDO31313.1 - 0.012 15.6 0.4 3.6 7.6 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain Nup35_RRM PF05172.13 KDO31313.1 - 0.024 14.6 0.0 3.4 7.7 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KDO31313.1 - 0.036 14.1 0.2 17 5.5 0.0 4.2 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KDO31313.1 - 1.3 9.1 7.0 7.1 6.8 0.1 4.1 4 0 0 4 4 4 0 Limkain b1 Coilin_N PF15862.5 KDO31313.1 - 6.9 6.5 0.0 6.9 6.5 0.0 6.5 5 3 1 6 6 6 0 Coilin N-terminus RCC1 PF00415.18 KDO31314.1 - 3.1e-69 229.4 13.3 1.5e-11 44.7 0.0 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO31314.1 - 8.4e-36 121.1 34.1 2.3e-08 33.6 1.9 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SecY PF00344.20 KDO31315.1 - 1.5e-68 231.3 16.1 1.9e-68 231.0 16.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KDO31315.1 - 6.6e-15 54.7 0.1 2.3e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p 7tm_3 PF00003.22 KDO31316.1 - 5.2e-42 144.2 25.4 9.1e-42 143.4 25.4 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RIFIN PF02009.16 KDO31316.1 - 0.49 10.2 2.8 0.58 10.0 0.3 2.1 2 0 0 2 2 2 0 Rifin TssN PF17555.2 KDO31316.1 - 2.7 7.3 17.7 2 7.8 6.1 2.2 1 1 1 2 2 2 0 Type VI secretion system, TssN 7tm_3 PF00003.22 KDO31317.1 - 4.7e-37 128.0 26.2 5.3e-37 127.8 25.2 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_3 PF00003.22 KDO31318.1 - 5.1e-37 127.9 27.5 5.7e-37 127.7 26.2 1.7 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PDZ_1 PF12812.7 KDO31320.1 - 1.8e-31 108.0 0.0 2.2e-20 72.4 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KDO31320.1 - 7.1e-19 69.2 1.6 5.3e-18 66.4 0.1 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KDO31320.1 - 3.7e-13 49.6 0.0 0.0024 18.1 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KDO31320.1 - 7.8e-13 48.1 1.5 0.071 13.0 0.1 5.1 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 KDO31320.1 - 4.9e-08 33.2 0.0 0.12 12.7 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 KDO31320.1 - 0.0025 17.7 0.2 0.079 12.9 0.0 3.1 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 KDO31320.1 - 0.005 15.6 0.3 0.017 13.8 0.1 1.8 2 0 0 2 2 2 1 Peptidase S46 DUF31 PF01732.16 KDO31320.1 - 0.028 14.0 0.4 0.038 13.5 0.4 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Trypsin PF00089.26 KDO31320.1 - 0.032 14.0 0.5 0.86 9.4 0.1 3.1 3 1 0 3 3 3 0 Trypsin Peptidase_S7 PF00949.21 KDO31320.1 - 0.11 12.3 0.9 0.23 11.3 0.9 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease zf-TAZ PF02135.16 KDO31321.1 - 0.018 15.5 2.0 0.018 15.5 2.0 2.0 1 1 1 2 2 2 0 TAZ zinc finger Pacs-1 PF10254.9 KDO31321.1 - 0.042 12.8 0.0 0.05 12.6 0.0 1.0 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein DUF4247 PF14042.6 KDO31321.1 - 0.14 12.9 0.0 0.16 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) DUF4296 PF14129.6 KDO31322.1 - 0.00028 21.4 3.6 0.28 11.8 0.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4296) DUF2275 PF10039.9 KDO31322.1 - 0.032 14.3 0.4 0.049 13.7 0.4 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Curto_V3 PF07436.11 KDO31322.1 - 0.091 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Curtovirus V3 protein SnoaL_2 PF12680.7 KDO31322.1 - 0.44 11.2 2.7 11 6.7 0.2 2.7 2 1 0 2 2 2 0 SnoaL-like domain PX PF00787.24 KDO31323.1 - 3.3e-13 49.6 0.0 5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 PX domain Rubis-subs-bind PF09273.11 KDO31324.1 - 4.8e-16 59.6 0.0 8.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KDO31324.1 - 2.3e-08 34.6 0.2 1.7e-07 31.8 0.0 2.3 2 1 0 2 2 2 1 SET domain Mito_carr PF00153.27 KDO31325.1 - 1.1e-69 230.5 0.1 2.5e-23 81.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KDO31325.1 - 0.0018 18.7 0.3 0.0082 16.5 0.3 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family His_Phos_1 PF00300.22 KDO31326.1 - 3.6e-05 23.5 0.0 7.3e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NMT1 PF09084.11 KDO31326.1 - 0.0099 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Peptidase_A22B PF04258.13 KDO31327.1 - 3.7e-60 203.9 8.1 5.6e-60 203.3 8.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KDO31327.1 - 0.0013 18.7 0.1 0.0082 16.1 0.0 2.3 2 0 0 2 2 2 1 PA domain DUF4395 PF14340.6 KDO31327.1 - 0.0018 18.6 4.7 0.0018 18.6 4.7 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4395) Cep57_MT_bd PF06657.13 KDO31328.1 - 0.029 14.8 1.4 0.029 14.8 1.4 2.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 KDO31328.1 - 0.16 11.3 3.8 0.23 10.8 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PK PF00224.21 KDO31329.1 - 4.6e-145 482.9 1.0 4.6e-145 482.9 1.0 1.5 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KDO31329.1 - 1.4e-29 102.6 0.6 3.6e-29 101.4 0.2 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KDO31329.1 - 0.00033 19.8 0.4 0.00082 18.6 0.4 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AIDA PF16168.5 KDO31329.1 - 1.7 8.8 4.5 0.49 10.5 0.8 2.0 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk Kdo PF06293.14 KDO31331.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KDO31332.1 - 6.4e-16 58.5 28.1 0.0027 18.5 0.1 11.4 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31332.1 - 1.5e-09 38.1 1.5 1.5 9.2 0.0 7.4 5 3 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 KDO31332.1 - 9.6e-08 32.4 0.4 2.1e-07 31.3 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO31332.1 - 1.7e-06 27.8 0.3 4.3e-06 26.5 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO31332.1 - 1.4e-05 24.3 0.1 3.5e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KDO31332.1 - 0.00019 20.8 0.6 0.00061 19.2 0.1 2.1 2 0 0 2 2 2 1 EF hand Nup160 PF11715.8 KDO31332.1 - 0.00054 18.7 3.9 0.15 10.6 0.2 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 EF-hand_6 PF13405.6 KDO31332.1 - 0.0033 17.2 0.1 0.013 15.4 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain DUF3108 PF11306.8 KDO31332.1 - 0.068 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) DAGK_cat PF00781.24 KDO31333.1 - 6.8e-27 93.6 0.0 1.2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PatG_C PF18065.1 KDO31333.1 - 0.031 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 PatG C-terminal LSDAT_prok PF18171.1 KDO31333.1 - 0.049 12.9 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote TPR_2 PF07719.17 KDO31337.1 - 5.4e-13 48.0 4.3 0.00029 20.7 1.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31337.1 - 1.2e-11 43.9 3.4 0.00032 20.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO31337.1 - 1.3e-06 28.0 1.2 0.00022 20.8 1.5 2.7 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 KDO31337.1 - 2.5e-06 28.0 2.1 2.5e-06 28.0 2.1 4.6 3 3 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO31337.1 - 0.00018 21.9 2.9 0.00018 21.9 2.9 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO31337.1 - 0.00046 20.4 11.3 0.00087 19.5 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31337.1 - 0.0013 19.4 21.9 0.022 15.6 0.5 6.6 5 3 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO31337.1 - 0.0038 17.3 1.0 0.0038 17.3 1.0 4.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31337.1 - 0.0047 17.0 0.2 5.9 7.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO31337.1 - 0.0058 16.6 1.4 2.8 8.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 KDO31337.1 - 0.014 15.4 0.4 0.29 11.2 0.1 3.1 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KDO31337.1 - 0.18 11.9 0.0 0.18 11.9 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat NARP1 PF12569.8 KDO31337.1 - 0.62 8.9 20.6 0.0078 15.2 3.8 2.7 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 KDO31337.1 - 0.9 10.1 5.2 10 6.8 0.3 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat COX4 PF02936.14 KDO31338.1 - 0.00076 19.5 0.0 0.00089 19.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.13 KDO31338.1 - 0.027 14.5 0.1 0.033 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) Isy1 PF06246.12 KDO31339.1 - 2.4e-67 227.2 5.9 2.8e-67 227.0 5.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family GPW_gp25 PF04965.14 KDO31339.1 - 0.0018 18.0 0.9 2 8.2 0.1 3.0 3 0 0 3 3 3 2 Gene 25-like lysozyme DUF2526 PF10735.9 KDO31339.1 - 1.4 9.1 5.7 1.3 9.2 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2526) Adaptin_N PF01602.20 KDO31340.1 - 2.7e-139 465.1 18.6 5.2e-137 457.6 18.6 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KDO31340.1 - 7.8e-50 169.1 15.3 8.9e-43 146.1 0.1 4.6 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KDO31340.1 - 7.8e-22 77.5 0.0 2.9e-21 75.6 0.0 2.1 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KDO31340.1 - 1.4e-18 67.1 3.9 2.2e-05 24.7 0.0 5.5 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 KDO31340.1 - 8.7e-13 47.3 3.2 0.0013 18.8 0.0 6.1 6 0 0 6 6 5 2 HEAT repeat Arm PF00514.23 KDO31340.1 - 9.8e-08 31.8 1.3 0.0021 18.1 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KDO31340.1 - 2.4e-07 30.3 2.3 0.00016 21.0 0.2 2.6 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 KDO31340.1 - 1.9e-05 24.3 0.9 0.43 10.1 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal Arm_2 PF04826.13 KDO31340.1 - 3.2e-05 23.5 0.0 0.00014 21.5 0.0 2.1 1 1 0 1 1 1 1 Armadillo-like UNC45-central PF11701.8 KDO31340.1 - 0.00025 21.1 1.3 0.12 12.4 0.0 3.7 3 2 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KDO31340.1 - 0.00049 20.5 2.1 3.1 8.4 0.0 4.7 5 0 0 5 5 4 2 HEAT-like repeat RTP1_C1 PF10363.9 KDO31340.1 - 0.0011 19.2 5.5 2.7 8.2 0.1 4.6 2 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_adaptinC2 PF02883.20 KDO31340.1 - 0.005 17.1 0.2 0.012 15.9 0.2 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 KDO31340.1 - 0.042 14.2 2.5 13 6.2 0.0 4.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sec7_N PF12783.7 KDO31340.1 - 0.56 10.1 6.5 0.59 10.0 0.5 3.4 2 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 KDO31340.1 - 1.6 8.6 6.8 2.6 8.0 0.5 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) zf-C3HC4_2 PF13923.6 KDO31341.1 - 1.1e-06 28.3 6.6 1.1e-06 28.3 6.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO31341.1 - 1.5e-06 28.1 7.4 3.5e-06 26.9 7.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO31341.1 - 1.5e-06 27.9 6.6 3.5e-06 26.8 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KDO31341.1 - 0.00012 22.2 9.5 0.00025 21.1 9.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KDO31341.1 - 0.00078 19.5 7.0 0.0017 18.4 7.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KDO31341.1 - 0.0012 18.8 8.6 0.0023 17.8 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KDO31341.1 - 0.015 15.7 10.2 0.096 13.0 10.5 2.1 1 1 1 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 KDO31341.1 - 0.017 15.0 6.1 0.047 13.6 6.1 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein ADIP PF11559.8 KDO31341.1 - 0.04 14.0 0.8 0.04 14.0 0.8 4.8 2 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding FYVE_2 PF02318.16 KDO31341.1 - 0.063 13.5 6.4 0.3 11.3 6.4 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 KDO31341.1 - 0.14 12.0 7.9 0.46 10.4 7.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Shugoshin_N PF07558.11 KDO31341.1 - 0.17 11.7 4.6 8.8 6.3 0.1 3.9 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region zf-C3HC4_3 PF13920.6 KDO31341.1 - 0.3 11.0 11.8 0.79 9.6 11.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Podoplanin PF05808.11 KDO31341.1 - 0.51 10.4 2.3 0.85 9.7 0.3 2.2 2 0 0 2 2 2 0 Podoplanin DUF4472 PF14739.6 KDO31341.1 - 1.1 10.0 24.2 0.034 14.9 5.1 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) CtIP_N PF10482.9 KDO31341.1 - 3.4 7.7 14.4 3.9 7.5 0.5 4.5 3 1 1 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain NUDIX PF00293.28 KDO31342.1 - 6.4e-10 39.2 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.32 KDO31343.1 - 7.7e-18 64.5 13.6 8.5e-06 26.4 0.4 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31343.1 - 2e-05 24.8 0.0 0.99 9.7 0.0 3.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PapD_C PF02753.17 KDO31343.1 - 0.023 15.1 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain PQQ PF01011.21 KDO31343.1 - 0.041 13.8 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KDO31343.1 - 0.15 10.6 0.1 0.51 8.8 0.1 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1816 PF08846.10 KDO31344.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) Peroxidase_ext PF11895.8 KDO31346.1 - 2.5 8.1 5.3 0.24 11.4 0.9 1.5 2 0 0 2 2 2 0 Fungal peroxidase extension region GREB1 PF15782.5 KDO31347.1 - 0.049 10.8 8.7 0.062 10.4 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YAcAr PF10686.9 KDO31347.1 - 0.081 12.9 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family SRP-alpha_N PF04086.13 KDO31347.1 - 0.74 9.7 22.4 1 9.2 22.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Suf PF05843.14 KDO31347.1 - 1.9 8.4 11.6 3 7.8 11.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase_Tyr PF07714.17 KDO31348.1 - 6.2e-33 114.2 0.0 8.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31348.1 - 1.2e-26 93.7 0.0 1.8e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 KDO31348.1 - 2.2e-13 50.4 0.0 4.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 KDO31349.1 - 4e-08 32.8 0.8 4.6e-08 32.6 0.8 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO31350.1 - 4.2e-17 62.0 0.0 8.7e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IstB_IS21_ATP PF08483.11 KDO31350.1 - 0.16 11.9 0.3 10 6.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal HMG_CoA_synt_C PF08540.10 KDO31351.1 - 2.4e-84 283.3 0.0 3.4e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KDO31351.1 - 2.5e-84 281.5 2.2 3.1e-81 271.4 0.1 2.3 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 KDO31351.1 - 9.4e-13 48.3 3.5 9.4e-13 48.3 3.5 2.5 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KDO31351.1 - 4.6e-10 39.2 7.0 2.2e-06 27.4 2.7 3.7 2 1 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2614 PF11023.8 KDO31351.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain Thiolase_N PF00108.23 KDO31351.1 - 0.34 10.2 2.2 2.8 7.2 1.6 2.4 2 0 0 2 2 2 0 Thiolase, N-terminal domain Cupin_8 PF13621.6 KDO31354.1 - 4.7e-19 69.1 0.1 4.1e-17 62.7 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KDO31354.1 - 1.1e-13 51.6 0.6 2.4e-13 50.5 0.1 1.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.7 KDO31354.1 - 3.2e-08 33.3 0.1 6.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO31354.1 - 1.3e-05 24.9 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cupin_1 PF00190.22 KDO31354.1 - 0.0079 15.8 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Cupin Cupin_4 PF08007.12 KDO31354.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 KDO31354.1 - 0.08 12.7 0.0 0.47 10.2 0.0 2.2 3 0 0 3 3 3 0 Cupin domain fn3 PF00041.21 KDO31357.1 - 2.4e-33 114.3 28.7 0.00011 22.5 0.1 11.2 12 0 0 12 12 12 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO31357.1 - 0.011 16.3 19.3 0.39 11.3 0.0 6.9 7 0 0 7 7 7 0 Purple acid Phosphatase, N-terminal domain Pkinase PF00069.25 KDO31358.1 - 2.9e-79 266.1 0.0 4e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31358.1 - 2.1e-46 158.3 0.0 3.2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KDO31358.1 - 1.3e-06 28.7 2.9 0.00037 20.8 0.1 6.5 4 2 2 6 6 6 2 HEAT repeats Arm PF00514.23 KDO31358.1 - 3.4e-06 26.9 24.1 0.028 14.5 0.1 7.1 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 KDO31358.1 - 5.1e-06 26.0 0.0 0.00053 19.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO31358.1 - 0.00056 18.8 0.0 0.00095 18.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO31358.1 - 0.00082 18.4 0.2 0.0024 16.9 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain HEAT_EZ PF13513.6 KDO31358.1 - 0.00091 19.7 0.4 0.00091 19.7 0.4 6.2 6 1 2 8 8 7 2 HEAT-like repeat HEAT PF02985.22 KDO31358.1 - 0.00095 19.2 14.3 0.04 14.2 0.2 5.8 6 0 0 6 6 5 2 HEAT repeat Kdo PF06293.14 KDO31358.1 - 0.027 13.8 0.2 0.071 12.4 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO31358.1 - 0.027 14.4 9.0 0.045 13.7 0.0 4.2 3 2 0 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO31358.1 - 0.03 13.8 0.2 0.082 12.4 0.2 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KDO31358.1 - 0.043 13.4 0.4 0.16 11.6 0.2 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 KDO31358.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Ephrin_rec_like PF07699.13 KDO31359.1 - 1.8e-12 46.8 40.0 1.3e-06 28.1 3.7 4.0 1 1 4 5 5 5 5 Putative ephrin-receptor like NCD3G PF07562.14 KDO31359.1 - 1.5e-06 28.1 12.5 9.2e-05 22.3 4.4 3.7 3 1 1 4 4 4 3 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KDO31359.1 - 4.3e-05 23.8 15.2 0.032 14.6 1.5 3.7 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region Furin-like PF00757.20 KDO31359.1 - 0.0094 15.8 5.6 0.031 14.2 5.5 1.8 1 1 0 1 1 1 1 Furin-like cysteine rich region DUF3677 PF12432.8 KDO31360.1 - 5.8e-06 26.5 0.3 2.4e-05 24.6 0.3 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) CDC45 PF02724.14 KDO31360.1 - 8.8 4.5 16.2 18 3.5 16.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Cofilin_ADF PF00241.20 KDO31361.1 - 1e-18 67.3 0.0 3.5e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CholecysA-Rec_N PF09193.10 KDO31361.1 - 0.13 12.2 0.2 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Cholecystokinin A receptor, N-terminal SRP19 PF01922.17 KDO31362.1 - 8.3e-26 90.8 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Collagen PF01391.18 KDO31362.1 - 0.41 10.4 23.8 3 7.7 23.8 2.4 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4296 PF14129.6 KDO31363.1 - 0.054 14.1 7.1 1.1 9.9 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) Speriolin_C PF15059.6 KDO31363.1 - 0.1 12.7 0.9 0.29 11.2 0.1 2.1 2 1 0 2 2 2 0 Speriolin C-terminus Caskin-tail PF16632.5 KDO31363.1 - 1.3 9.5 5.9 34 4.9 0.0 3.6 3 1 0 3 3 3 0 C-terminal region of Caskin Rad10 PF03834.14 KDO31364.1 - 8.1e-31 106.4 0.0 1.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KDO31364.1 - 2.2e-06 28.2 0.0 3.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KDO31364.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 KDO31364.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Sec66 PF09802.9 KDO31365.1 - 5.7e-16 58.6 3.1 7.7e-16 58.2 3.1 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SNARE PF05739.19 KDO31366.1 - 2e-12 46.9 0.1 6.6e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KDO31366.1 - 1.7e-05 24.6 14.1 4.2e-05 23.3 11.8 2.2 2 1 0 2 2 2 1 Syntaxin PNKP_ligase PF16542.5 KDO31366.1 - 0.024 14.1 0.5 0.036 13.6 0.5 1.2 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain Syntaxin_2 PF14523.6 KDO31366.1 - 0.091 13.1 6.6 0.2 12.1 2.2 2.6 2 1 0 2 2 2 0 Syntaxin-like protein MCPsignal PF00015.21 KDO31366.1 - 0.33 10.7 2.6 0.39 10.5 0.7 1.9 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2203 PF09969.9 KDO31366.1 - 2.2 9.0 6.8 6.1 7.6 1.3 2.7 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4833 PF16117.5 KDO31367.1 - 1.6e-38 131.8 0.0 2.3e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) Ead_Ea22 PF13935.6 KDO31367.1 - 0.023 15.3 0.3 0.031 15.0 0.3 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein OmpH PF03938.14 KDO31367.1 - 0.12 12.7 6.8 0.18 12.2 6.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 KDO31367.1 - 0.27 10.3 3.2 0.38 9.8 3.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KDO31367.1 - 0.28 10.0 6.0 0.38 9.6 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LCD1 PF09798.9 KDO31367.1 - 0.31 9.5 2.3 0.38 9.2 2.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TEX13 PF15186.6 KDO31367.1 - 0.48 10.1 7.1 0.69 9.6 7.1 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF4407 PF14362.6 KDO31367.1 - 0.59 9.4 3.3 0.87 8.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rubella_E2 PF05749.11 KDO31367.1 - 0.92 8.9 5.5 0.67 9.4 3.3 1.6 1 1 0 2 2 2 0 Rubella membrane glycoprotein E2 PWI PF01480.17 KDO31369.1 - 1.2e-12 48.0 0.0 2.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KDO31369.1 - 4.5e-08 32.8 0.0 8.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 KDO31369.1 - 0.00057 20.0 27.4 0.0012 19.0 27.4 1.5 1 0 0 1 1 1 1 Fruit fly transformer protein PRP38_assoc PF12871.7 KDO31369.1 - 0.039 14.5 47.3 0.11 13.1 47.3 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RSRP PF17069.5 KDO31369.1 - 3.9 7.0 28.8 8.5 5.9 28.8 1.5 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Presenilin PF01080.17 KDO31369.1 - 4.3 6.0 7.3 6 5.5 7.3 1.2 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 KDO31370.1 - 0.00096 18.9 0.1 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MiaE_2 PF13794.6 KDO31370.1 - 0.024 14.4 0.8 0.038 13.7 0.8 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Tropomyosin_1 PF12718.7 KDO31370.1 - 0.094 12.9 2.1 0.19 11.9 2.1 1.4 1 0 0 1 1 1 0 Tropomyosin like LRR_4 PF12799.7 KDO31371.1 - 1.2e-15 57.3 0.0 0.2 12.2 0.0 6.7 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO31371.1 - 7.2e-10 38.1 15.6 0.037 14.1 0.1 8.8 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 KDO31371.1 - 8.5e-05 22.6 3.5 1.5e+02 3.6 0.0 8.0 9 1 0 9 9 9 0 Leucine Rich Repeat Pkinase PF00069.25 KDO31372.1 - 8.5e-59 199.1 0.0 1.1e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31372.1 - 4.3e-29 101.6 0.0 3e-28 98.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO31372.1 - 1.7e-05 24.3 0.0 3.4e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO31372.1 - 0.0004 20.0 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family tRNA_bind_3 PF17176.4 KDO31372.1 - 0.037 14.3 1.0 0.24 11.7 0.2 2.5 3 0 0 3 3 3 0 tRNA-binding domain Pkinase_fungal PF17667.1 KDO31372.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO31372.1 - 0.073 13.0 0.0 0.57 10.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RCC1 PF00415.18 KDO31373.1 - 1.1e-32 112.4 21.4 5.5e-10 39.7 0.4 7.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_1 PF00036.32 KDO31373.1 - 1e-26 90.4 10.9 4.5e-07 29.0 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO31373.1 - 1.4e-24 83.9 8.8 3.2e-05 23.5 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO31373.1 - 2.2e-19 68.0 14.8 2.1e-05 23.8 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO31373.1 - 3.5e-15 56.2 12.7 1.5e-07 31.8 3.0 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 KDO31373.1 - 2.3e-14 52.9 7.5 0.0014 18.5 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain pair RCC1_2 PF13540.6 KDO31373.1 - 1.6e-12 46.8 25.8 1.9e-05 24.3 0.1 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat EF-hand_10 PF14788.6 KDO31373.1 - 2.2e-07 30.6 2.4 0.0089 15.9 0.0 3.5 2 1 1 3 3 3 2 EF hand F5_F8_type_C PF00754.25 KDO31373.1 - 5.9e-05 23.2 0.2 0.00093 19.3 0.2 2.4 1 1 0 1 1 1 1 F5/8 type C domain DUF5000 PF16391.5 KDO31373.1 - 0.0022 18.1 0.0 0.46 10.6 0.0 2.7 1 1 0 1 1 1 1 Domain of unknown function EF-hand_9 PF14658.6 KDO31373.1 - 0.019 15.3 0.1 7.9 6.9 0.1 3.5 3 0 0 3 3 3 0 EF-hand domain Kelch_6 PF13964.6 KDO31373.1 - 0.2 12.0 1.7 47 4.5 0.1 4.3 5 0 0 5 5 5 0 Kelch motif Thioredoxin PF00085.20 KDO31374.1 - 1.5e-22 79.5 0.0 2.2e-19 69.3 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KDO31374.1 - 4.8e-10 39.6 0.0 1e-09 38.6 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO31374.1 - 0.003 17.7 0.1 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KDO31374.1 - 0.017 15.6 0.0 0.48 10.9 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain FSA_C PF10479.9 KDO31375.1 - 0.13 10.3 0.1 0.3 9.1 0.0 1.6 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Aconitase PF00330.20 KDO31376.1 - 3.2e-70 237.4 0.4 2.7e-68 231.1 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KDO31376.1 - 1.2e-17 64.5 0.0 2.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.32 KDO31377.1 - 0.0027 18.5 4.1 0.66 10.9 0.1 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Lzipper-MIP1 PF14389.6 KDO31377.1 - 3.6 8.0 12.5 0.32 11.3 2.0 3.9 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Fungal_TACC PF12709.7 KDO31377.1 - 7.1 7.2 13.5 6.1 7.4 0.0 5.3 5 1 1 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins HA PF03457.14 KDO31378.1 - 1.6e-46 156.5 0.3 1.8e-08 34.6 0.0 9.4 9 0 0 9 9 9 8 Helicase associated domain DUF2635 PF10948.8 KDO31378.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) HA PF03457.14 KDO31379.1 - 1e-33 115.5 0.0 1.1e-08 35.3 0.0 6.3 6 0 0 6 6 6 6 Helicase associated domain Aminotran_1_2 PF00155.21 KDO31380.1 - 2.1e-44 152.2 0.0 2.7e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DASH_Duo1 PF08651.10 KDO31381.1 - 0.018 14.8 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 DASH_Hsk3 PF08227.11 KDO31381.1 - 0.098 13.0 4.7 0.17 12.2 4.7 1.5 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like HA PF03457.14 KDO31382.1 - 4.7e-40 135.7 0.4 4.1e-07 30.2 0.0 7.2 6 1 1 7 7 7 6 Helicase associated domain E1_4HB PF16191.5 KDO31382.1 - 0.19 11.9 1.8 4.5 7.5 0.3 3.0 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Glyco_hydro_31 PF01055.26 KDO31383.1 - 1.5e-138 462.7 0.8 1.9e-138 462.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KDO31383.1 - 1.6e-28 99.2 0.0 5.4e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KDO31383.1 - 2.1e-09 37.1 21.2 2.3e-06 27.4 4.4 2.8 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KDO31383.1 - 1.9e-08 34.5 0.3 8.7e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like HA PF03457.14 KDO31384.1 - 2.8e-43 146.1 0.0 1.9e-07 31.3 0.0 9.1 10 0 0 10 10 10 7 Helicase associated domain E1_4HB PF16191.5 KDO31384.1 - 1.7 8.9 4.4 7.8 6.8 0.3 3.6 4 0 0 4 4 4 0 Ubiquitin-activating enzyme E1 four-helix bundle Aquarius_N PF16399.5 KDO31385.1 - 1.2e-144 483.3 0.0 1.6e-144 482.9 0.0 1.0 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 KDO31385.1 - 1e-16 61.5 0.3 1.6e-15 57.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KDO31385.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO31385.1 - 1.2e-09 38.7 0.0 3.3e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO31385.1 - 4.5e-09 36.3 2.6 9e-08 32.1 0.3 3.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KDO31385.1 - 3.9e-06 26.8 0.6 0.00081 19.3 0.0 2.7 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 KDO31385.1 - 0.00022 20.7 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 KDO31385.1 - 0.00024 21.2 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KDO31385.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KDO31385.1 - 0.0036 17.7 1.1 0.017 15.5 0.2 2.7 1 1 1 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 KDO31385.1 - 0.004 16.4 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KDO31385.1 - 0.0054 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KDO31385.1 - 0.0075 15.9 0.8 0.13 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KDO31385.1 - 0.0081 16.4 0.0 0.041 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KDO31385.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DnaB_C PF03796.15 KDO31385.1 - 0.035 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain bPH_2 PF03703.14 KDO31385.1 - 0.17 12.1 0.1 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial PH domain ArsC PF03960.15 KDO31386.1 - 2.4e-10 40.2 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ArsC family ENTH PF01417.20 KDO31387.1 - 3.1e-35 120.9 0.7 4.6e-35 120.4 0.2 1.6 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 KDO31387.1 - 0.0018 17.3 0.1 0.0029 16.7 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KDO31387.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 VHS domain Vps54_N PF10475.9 KDO31387.1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex BT1 PF03092.16 KDO31388.1 - 0.28 9.4 0.3 0.35 9.1 0.3 1.1 1 0 0 1 1 1 0 BT1 family FYVE PF01363.21 KDO31390.1 - 3.2e-19 68.8 21.5 1.5e-10 41.1 12.3 2.4 2 0 0 2 2 2 2 FYVE zinc finger Lipase_3 PF01764.25 KDO31390.1 - 5e-19 68.6 0.0 9.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 KDO31390.1 - 0.0005 20.0 2.9 0.00073 19.5 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pex24p PF06398.11 KDO31390.1 - 0.1 11.6 1.2 0.15 11.0 1.2 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-AN1 PF01428.16 KDO31390.1 - 6.7 7.0 12.7 0.3 11.3 4.2 2.7 2 0 0 2 2 2 0 AN1-like Zinc finger Rpr2 PF04032.16 KDO31390.1 - 7.4 6.9 8.2 3 8.2 3.0 2.8 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RRM_1 PF00076.22 KDO31392.1 - 2.6e-53 177.7 0.0 1.8e-17 62.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO31392.1 - 5.3e-10 39.3 0.0 0.077 13.1 0.0 3.6 2 1 1 3 3 3 3 RNA recognition motif RRM_occluded PF16842.5 KDO31392.1 - 3.3e-09 36.5 0.0 9.7e-05 22.2 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KDO31392.1 - 1.1e-06 28.6 0.0 0.066 13.2 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KDO31392.1 - 0.0001 22.6 0.0 13 6.0 0.0 4.5 3 2 2 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KDO31392.1 - 0.0018 18.3 0.0 23 5.1 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif RRM_Rrp7 PF17799.1 KDO31392.1 - 0.011 15.5 0.0 5.3 6.8 0.0 2.9 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 KDO31392.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 PHD PF00628.29 KDO31393.1 - 0.003 17.4 6.9 0.0063 16.4 6.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KDO31393.1 - 0.0067 16.6 1.0 0.014 15.7 1.0 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.22 KDO31393.1 - 0.0076 16.1 3.3 0.02 14.8 3.3 1.6 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 KDO31393.1 - 0.04 14.1 1.6 0.074 13.2 1.6 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 KDO31393.1 - 0.52 10.7 2.6 0.98 9.8 1.6 1.9 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 KDO31393.1 - 0.73 9.8 3.8 1.1 9.2 3.8 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KDO31393.1 - 1 8.9 5.0 2.7 7.6 5.0 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KDO31393.1 - 1.1 9.2 7.8 2.4 8.2 7.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KDO31393.1 - 1.5 8.9 7.5 6.8 6.8 2.2 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid CDC45 PF02724.14 KDO31393.1 - 1.8 6.8 7.2 3.3 5.9 7.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M20 PF01546.28 KDO31395.1 - 6.1e-27 94.7 0.0 7.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO31395.1 - 1.3e-16 60.5 0.0 2.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KDO31396.1 - 9.4e-31 107.1 0.0 1.2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO31396.1 - 4.7e-16 58.7 0.0 7.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KDO31397.1 - 3.7e-27 95.4 0.0 4.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO31397.1 - 9.7e-16 57.6 0.0 1.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 KDO31399.1 - 7.3e-133 441.9 0.0 1.2e-65 221.6 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31399.1 - 3.4e-52 177.3 0.0 3.7e-26 92.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase WW PF00397.26 KDO31399.1 - 1.5e-18 66.6 4.5 2.2e-12 46.8 3.5 2.7 2 0 0 2 2 2 2 WW domain Haspin_kinase PF12330.8 KDO31399.1 - 2e-08 33.6 0.2 0.0019 17.2 0.1 2.3 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KDO31399.1 - 5.4e-06 26.5 0.8 0.11 12.4 0.1 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO31399.1 - 8.3e-06 25.3 2.6 0.043 13.2 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO31399.1 - 1.4e-05 24.6 0.0 0.022 14.1 0.0 2.7 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KDO31399.1 - 0.00035 20.2 0.9 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 KDO31399.1 - 0.0045 15.8 0.5 0.83 8.4 0.1 2.4 2 0 0 2 2 2 2 Fungal protein kinase Cwf_Cwc_15 PF04889.12 KDO31399.1 - 0.012 15.4 10.3 0.021 14.6 10.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FTA2 PF13095.6 KDO31399.1 - 0.018 14.6 0.1 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 KDO31399.1 - 0.1 11.4 0.1 11 4.7 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 KDO31399.1 - 0.11 12.0 0.1 18 4.9 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 KDO31399.1 - 0.2 10.6 0.2 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Importin_rep_4 PF18808.1 KDO31399.1 - 2.3 8.6 4.4 5.9 7.3 4.4 1.7 1 0 0 1 1 1 0 Importin repeat EF-hand_7 PF13499.6 KDO31400.1 - 8.1e-16 58.2 1.1 8.9e-16 58.1 1.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO31400.1 - 7.7e-15 53.3 4.8 1.3e-07 30.7 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO31400.1 - 5.2e-14 51.8 0.6 7.8e-14 51.3 0.1 1.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO31400.1 - 1.2e-13 49.8 1.5 3.3e-06 26.6 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO31400.1 - 4e-08 32.4 9.7 0.00016 21.0 0.3 3.0 2 1 1 3 3 3 2 EF hand EF-hand_4 PF12763.7 KDO31400.1 - 0.086 12.8 3.4 1.5 8.8 0.2 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand RseC_MucC PF04246.12 KDO31401.1 - 0.51 10.3 2.7 3.7 7.5 0.2 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PTS_2-RNA PF01885.16 KDO31402.1 - 2.9e-60 203.4 0.0 3.3e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ank_4 PF13637.6 KDO31404.1 - 1e-10 41.9 0.5 6.5e-06 26.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31404.1 - 2.2e-09 37.4 0.7 1.9e-07 31.2 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31404.1 - 7.5e-08 32.9 0.1 1.7e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO31404.1 - 1.6e-06 28.3 0.2 0.0016 18.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO31404.1 - 0.00026 21.2 0.6 0.029 14.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat DUF5069 PF16798.5 KDO31404.1 - 0.4 10.9 6.1 7.2 6.8 1.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5069) Troponin PF00992.20 KDO31406.1 - 0.01 16.1 1.4 0.022 15.1 1.4 1.5 1 0 0 1 1 1 0 Troponin FlhE PF06366.13 KDO31406.1 - 0.013 15.5 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FlhE APG6_N PF17675.1 KDO31406.1 - 0.029 14.9 4.3 0.064 13.8 4.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 KDO31406.1 - 0.11 12.6 1.8 1.7 8.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KDO31406.1 - 0.12 11.9 5.2 0.26 10.7 2.0 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 KDO31406.1 - 0.49 11.0 7.6 2.1 9.0 0.5 3.3 2 1 1 3 3 3 0 SlyX Trimer_CC PF08954.11 KDO31406.1 - 0.61 9.7 3.6 17 5.1 0.1 3.6 3 0 0 3 3 3 0 Trimerisation motif Lectin_N PF03954.14 KDO31406.1 - 3.2 7.5 7.8 13 5.5 0.9 2.7 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Fez1 PF06818.15 KDO31406.1 - 3.5 8.0 8.6 4.9 7.6 1.7 2.1 1 1 2 3 3 3 0 Fez1 Lebercilin PF15619.6 KDO31407.1 - 0.0084 15.8 1.6 0.021 14.5 1.6 1.6 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.11 KDO31407.1 - 0.31 11.3 1.9 0.95 9.7 1.9 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spc29 PF17082.5 KDO31407.1 - 0.98 9.2 2.4 14 5.5 0.3 2.4 2 0 0 2 2 2 0 Spindle Pole Component 29 Hydrolase_4 PF12146.8 KDO31408.1 - 2.2e-10 40.2 0.1 1.9e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO31408.1 - 2.3e-08 34.9 0.1 4.2e-08 34.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KDO31408.1 - 0.00051 19.7 0.0 0.007 16.0 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KDO31408.1 - 0.01 15.5 0.2 0.076 12.6 0.2 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Succ_CoA_lig PF13607.6 KDO31408.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain RabGAP-TBC PF00566.18 KDO31409.1 - 3.3e-51 174.0 0.0 5.3e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.17 KDO31410.1 - 3.1e-57 193.8 0.0 3.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31410.1 - 3.1e-54 184.1 0.0 3.8e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO31410.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KDO31410.1 - 0.0009 18.4 0.1 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KDO31410.1 - 0.00093 19.2 0.1 0.0044 17.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO31410.1 - 0.035 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Apc13p PF05839.11 KDO31411.1 - 2.9e-05 24.2 0.9 0.0002 21.5 0.9 1.9 1 1 0 1 1 1 1 Apc13p protein BolA PF01722.18 KDO31412.1 - 1.5e-19 70.0 0.0 3.7e-19 68.8 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Ribosomal_L7Ae PF01248.26 KDO31413.1 - 6e-26 90.0 0.0 8.2e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KDO31413.1 - 4.6e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KDO31413.1 - 0.0052 16.8 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 FHA PF00498.26 KDO31414.1 - 3.4e-16 59.4 0.0 5.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO31414.1 - 9.1e-07 29.1 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Transformer PF06495.11 KDO31414.1 - 0.0018 18.4 7.4 0.0028 17.8 7.4 1.3 1 0 0 1 1 1 1 Fruit fly transformer protein Corona_nucleoca PF00937.18 KDO31414.1 - 0.96 8.4 5.3 0.55 9.2 3.6 1.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DNA_pol_A_exo1 PF01612.20 KDO31415.1 - 2.7e-20 72.8 0.0 5.3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease UPF0242 PF06785.11 KDO31416.1 - 0.87 9.7 12.6 0.92 9.6 11.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KDO31416.1 - 1.9 7.8 7.5 2.9 7.1 7.5 1.2 1 0 0 1 1 1 0 FAM76 protein Glyco_hydro_3 PF00933.21 KDO31417.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain CENP-C_mid PF15620.6 KDO31417.1 - 5.1 7.0 8.0 0.65 9.9 2.7 2.1 2 0 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Pkinase PF00069.25 KDO31418.1 - 6.8e-77 258.4 0.0 8.1e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31418.1 - 5.8e-33 114.3 0.0 7.4e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO31418.1 - 1.2e-07 31.3 0.1 3.6e-05 23.2 0.0 3.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO31418.1 - 5.6e-06 25.4 0.2 9.8e-06 24.6 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO31418.1 - 0.0016 17.9 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KDO31418.1 - 0.0065 15.5 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KDO31418.1 - 0.019 14.9 0.1 2 8.3 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO31418.1 - 0.075 12.5 0.3 1.1 8.7 0.1 2.3 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL DUF1279 PF06916.13 KDO31419.1 - 1.4e-12 48.0 1.2 4.9e-12 46.2 1.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3388 PF11868.8 KDO31419.1 - 0.055 12.8 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) ELMO_CED12 PF04727.13 KDO31420.1 - 1.7e-05 25.0 0.0 2.5e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 ELMO/CED-12 family Hydantoinase_A PF01968.18 KDO31421.1 - 1.9 7.7 6.9 1.5 8.0 1.4 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Myb_DNA-binding PF00249.31 KDO31422.1 - 6.4e-13 48.7 0.1 8.8e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO31422.1 - 4e-05 23.8 0.1 6.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO31422.1 - 0.018 14.9 0.2 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 Myb DNA-binding like MMS1_N PF10433.9 KDO31423.1 - 1.6e-104 350.3 0.0 2.2e-104 349.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KDO31423.1 - 3.1e-38 131.9 0.1 1e-36 126.9 0.1 2.8 3 0 0 3 3 3 1 CPSF A subunit region RabGAP-TBC PF00566.18 KDO31424.1 - 9.4e-33 113.7 0.0 1.4e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDZ PF00595.24 KDO31424.1 - 3.9e-07 30.3 0.0 8.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO31424.1 - 2.8e-06 27.1 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO31424.1 - 0.0063 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain fn3 PF00041.21 KDO31424.1 - 0.0078 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Rhodanese PF00581.20 KDO31424.1 - 0.077 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain PDEase_I PF00233.19 KDO31425.1 - 7.4e-58 196.1 0.2 1.3e-57 195.2 0.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 KDO31425.1 - 1.7e-10 40.9 0.0 4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EAV_GP5 PF15981.5 KDO31425.1 - 0.024 15.1 0.2 0.67 10.4 0.0 3.0 3 0 0 3 3 3 0 Envelope glycoprotein GP 5 of equine arteritis virus CDC27 PF09507.10 KDO31426.1 - 2.4e-13 50.3 19.6 5.5e-13 49.1 19.6 1.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DTHCT PF08070.11 KDO31426.1 - 0.038 14.7 9.5 0.038 14.7 9.5 3.8 2 2 2 4 4 4 0 DTHCT (NUC029) region Cwf_Cwc_15 PF04889.12 KDO31426.1 - 0.19 11.4 4.0 0.3 10.8 4.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sensor PF13796.6 KDO31427.1 - 0.0024 18.0 16.6 0.032 14.3 3.6 2.2 2 0 0 2 2 2 2 Putative sensor EF-hand_7 PF13499.6 KDO31428.1 - 1.4e-07 31.9 0.0 3.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO31428.1 - 4.5e-05 22.7 0.0 0.052 13.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO31428.1 - 0.0018 18.1 0.0 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KDO31428.1 - 0.055 13.3 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair ALMT PF11744.8 KDO31428.1 - 0.7 8.7 7.2 0.37 9.6 0.1 2.5 3 0 0 3 3 3 0 Aluminium activated malate transporter Methyltransf_23 PF13489.6 KDO31429.1 - 1.5e-10 41.2 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO31429.1 - 3.3e-10 40.5 0.1 5e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO31429.1 - 8.7e-09 35.3 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO31429.1 - 1.3e-07 32.1 0.0 2.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KDO31429.1 - 3.1e-07 30.3 0.1 4.1e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KDO31429.1 - 1.2e-06 29.2 0.0 1.7e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO31429.1 - 4.6e-05 22.9 0.0 5.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KDO31429.1 - 0.00018 21.2 0.1 0.00037 20.1 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.8 KDO31429.1 - 0.0043 16.2 0.1 0.0058 15.8 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.12 KDO31429.1 - 0.0074 15.8 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase VKOR PF07884.14 KDO31429.1 - 0.0099 16.1 0.6 0.015 15.5 0.0 1.6 2 0 0 2 2 2 1 Vitamin K epoxide reductase family MTS PF05175.14 KDO31429.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 KDO31429.1 - 0.055 13.1 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 SQS_PSY PF00494.19 KDO31430.1 - 4.6e-51 173.8 3.1 5.5e-51 173.6 3.1 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Rho_RNA_bind PF07497.12 KDO31430.1 - 0.15 11.9 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain BCIP PF13862.6 KDO31433.1 - 2.4e-47 161.4 0.0 3.3e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Exonuc_VII_L PF02601.15 KDO31434.1 - 0.03 13.9 1.8 0.19 11.2 3.3 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4089 PF13318.6 KDO31434.1 - 0.093 13.2 0.1 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) ApoLp-III PF07464.11 KDO31434.1 - 0.11 12.6 6.9 0.24 11.5 5.2 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DotU PF09850.9 KDO31434.1 - 0.22 11.2 4.8 0.54 9.9 1.2 2.5 2 1 0 2 2 2 0 Type VI secretion system protein DotU Rogdi_lz PF10259.9 KDO31434.1 - 0.37 10.2 7.2 0.36 10.3 5.5 1.6 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein Apolipoprotein PF01442.18 KDO31434.1 - 1.3 8.8 17.1 16 5.3 16.3 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 KDO31434.1 - 1.6 8.3 4.3 1 8.9 1.9 1.9 2 1 0 2 2 2 0 fzo-like conserved region TPR_12 PF13424.6 KDO31436.1 - 3.7e-13 49.6 0.4 5.9e-11 42.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO31436.1 - 5.9e-06 26.0 0.0 0.57 10.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31436.1 - 8.8e-06 25.5 0.3 0.28 11.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31436.1 - 1.5e-05 24.6 0.9 0.15 12.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Hydrolase PF00702.26 KDO31437.1 - 0.02 15.2 1.9 0.034 14.4 1.9 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KDO31437.1 - 0.031 14.4 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MASE2 PF05230.11 KDO31438.1 - 0.094 12.8 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 MASE2 domain DUF4598 PF15370.6 KDO31440.1 - 3.9e-20 72.4 0.9 4.2e-20 72.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Ank_2 PF12796.7 KDO31441.1 - 3.8e-07 30.6 0.0 0.011 16.4 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31441.1 - 2.1e-06 28.1 0.1 0.44 11.2 0.0 4.1 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31441.1 - 3.6e-06 26.9 5.4 0.099 13.3 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KDO31441.1 - 0.00013 22.1 0.3 1.1 9.7 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 KDO31441.1 - 0.016 14.5 9.9 0.029 13.6 9.9 1.4 1 1 0 1 1 1 0 Ion transport protein Ank PF00023.30 KDO31441.1 - 0.032 14.7 0.6 5.2 7.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat PKD_channel PF08016.12 KDO31441.1 - 5.3 5.6 7.4 0.31 9.7 1.5 1.8 2 0 0 2 2 2 0 Polycystin cation channel Ank_4 PF13637.6 KDO31442.1 - 1.1e-07 32.2 0.1 0.015 15.9 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31442.1 - 9.2e-07 29.4 0.0 0.00067 20.2 0.0 3.7 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO31442.1 - 8.7e-06 25.9 1.7 0.0069 16.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31442.1 - 1.3e-05 25.2 1.1 0.2 12.3 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KDO31442.1 - 0.37 11.3 2.3 75 4.0 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat BBL5 PF07289.11 KDO31443.1 - 4.3e-149 496.1 0.0 4.9e-149 495.9 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein PH_TFIIH PF08567.11 KDO31443.1 - 3.5e-05 24.1 0.0 0.099 13.0 0.0 2.5 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain bPH_3 PF14470.6 KDO31443.1 - 0.0005 20.4 0.0 0.01 16.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial PH domain Voldacs PF03517.13 KDO31443.1 - 0.001 19.2 0.0 0.51 10.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 KDO31443.1 - 0.004 17.3 0.0 0.18 12.0 0.1 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Pro_isomerase PF00160.21 KDO31444.1 - 4.1e-53 179.9 0.0 4.5e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 KDO31444.1 - 0.077 12.7 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) zf-RanBP PF00641.18 KDO31445.1 - 0.039 13.3 5.1 0.068 12.5 5.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others THRAP3_BCLAF1 PF15440.6 KDO31445.1 - 0.079 12.0 29.4 0.079 12.0 29.4 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family SR-25 PF10500.9 KDO31445.1 - 0.4 10.3 28.6 0.87 9.2 28.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3827 PF12877.7 KDO31445.1 - 1.5 7.1 16.5 1.9 6.7 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Presenilin PF01080.17 KDO31445.1 - 6.9 5.3 10.3 6.8 5.4 10.3 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_M1 PF01433.20 KDO31446.1 - 9e-26 90.8 0.1 1.8e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458_C PF17432.2 KDO31446.1 - 5.7e-18 65.4 5.4 1.1e-17 64.4 5.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1_N PF17900.1 KDO31446.1 - 8.6e-10 39.1 0.0 1.9e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 KDO31446.1 - 6.2e-09 36.2 0.0 1.6e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold EamA PF00892.20 KDO31447.1 - 4.4e-10 39.9 27.4 3.8e-05 23.9 11.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family MutL_C PF08676.11 KDO31448.1 - 3.3e-29 101.5 0.3 1.1e-28 99.9 0.3 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KDO31448.1 - 2.9e-22 78.6 0.0 2.1e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KDO31448.1 - 3.7e-11 43.0 0.0 8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KDO31448.1 - 1.1e-08 35.5 0.0 2.8e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rhodanese PF00581.20 KDO31449.1 - 3.3e-10 40.4 0.0 1.2e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Pterin_4a PF01329.19 KDO31450.1 - 7.5e-31 106.2 0.1 8.7e-31 106.0 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF2507 PF10702.9 KDO31451.1 - 0.024 14.6 0.6 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2507) DUF4472 PF14739.6 KDO31451.1 - 0.043 14.5 1.8 0.043 14.5 1.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Troponin PF00992.20 KDO31451.1 - 0.27 11.5 12.9 1.4 9.3 0.2 3.2 1 1 2 3 3 3 0 Troponin Cep57_CLD PF14073.6 KDO31451.1 - 0.67 10.0 15.0 0.22 11.5 5.9 3.3 1 1 1 3 3 3 0 Centrosome localisation domain of Cep57 KASH_CCD PF14662.6 KDO31451.1 - 0.78 9.5 14.3 0.47 10.3 0.6 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH PI3K_P85_iSH2 PF16454.5 KDO31451.1 - 3.7 7.1 9.7 0.45 10.1 3.6 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 KDO31451.1 - 3.9 7.5 6.1 5.4 7.1 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Arf PF00025.21 KDO31452.1 - 3.7e-39 134.0 0.0 4.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO31452.1 - 1.5e-09 38.1 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO31452.1 - 1.4e-08 34.5 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KDO31452.1 - 9.9e-05 21.8 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KDO31452.1 - 0.0003 20.2 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KDO31452.1 - 0.006 15.8 0.1 0.023 13.9 0.0 1.8 1 1 1 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KDO31452.1 - 0.012 15.6 0.0 0.75 9.7 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase Ca_hom_mod PF14798.6 KDO31452.1 - 0.022 13.9 0.1 0.027 13.6 0.1 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator GTP_EFTU PF00009.27 KDO31452.1 - 0.036 13.6 0.0 0.073 12.6 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO31452.1 - 0.048 13.7 0.0 0.088 12.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Abi_HHR PF07815.14 KDO31452.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.5 2 0 0 2 2 2 0 Abl-interactor HHR VPS13 PF16908.5 KDO31453.1 - 4.5e-28 98.6 0.0 1e-27 97.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KDO31453.1 - 1.3e-17 64.2 0.1 2.6e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KDO31453.1 - 2.1e-16 60.1 0.0 3.8e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KDO31453.1 - 2.2e-13 50.3 0.0 5.4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PDZ_2 PF13180.6 KDO31453.1 - 0.078 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 PDZ domain IQ PF00612.27 KDO31453.1 - 0.22 11.4 9.2 1.6 8.7 1.3 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-MYND PF01753.18 KDO31454.1 - 2e-08 34.2 15.9 4.8e-08 33.0 15.9 1.6 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 KDO31454.1 - 0.025 14.9 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-HIT PF04438.16 KDO31454.1 - 1.9 8.4 11.9 6.9 6.6 11.9 1.9 1 1 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KDO31454.1 - 6.8 7.1 16.9 1.1 9.6 13.0 1.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding TK PF00265.18 KDO31455.1 - 8.9e-60 201.6 0.0 1e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase PALP PF00291.25 KDO31456.1 - 4.8e-65 219.9 2.3 5.6e-65 219.7 2.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LSM PF01423.22 KDO31457.1 - 3.1e-22 78.0 0.2 3.6e-22 77.8 0.2 1.0 1 0 0 1 1 1 1 LSM domain Ribosomal_L37 PF08561.10 KDO31458.1 - 3.4e-09 37.3 4.4 3.9e-07 30.6 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 EF_assoc_1 PF08355.12 KDO31458.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Pyr_redox_2 PF07992.14 KDO31459.1 - 7.8e-58 196.0 0.5 1.1e-57 195.5 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO31459.1 - 4.6e-25 88.0 0.0 9.1e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO31459.1 - 2.4e-17 63.3 3.3 2.5e-13 50.4 0.0 3.1 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO31459.1 - 2.7e-07 30.2 0.4 0.00096 18.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO31459.1 - 6.8e-07 29.0 1.3 7.5e-06 25.5 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KDO31459.1 - 2e-06 27.2 0.2 2.9e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KDO31459.1 - 2.3e-05 23.8 0.5 7.2e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KDO31459.1 - 3e-05 22.9 0.9 0.00075 18.3 0.7 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KDO31459.1 - 3.8e-05 23.0 2.8 3.8e-05 23.0 2.8 2.3 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KDO31459.1 - 0.00012 21.4 0.0 0.0043 16.3 0.0 2.4 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KDO31459.1 - 0.0054 16.9 2.2 0.0084 16.3 1.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KDO31459.1 - 0.017 14.4 0.2 0.028 13.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KDO31459.1 - 0.091 12.3 5.4 0.68 9.5 4.3 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_RFF PF18321.1 KDO31459.1 - 0.1 13.0 0.1 7.8 7.0 0.0 3.2 4 0 0 4 4 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PA PF02225.22 KDO31460.1 - 2.2e-23 82.1 1.1 2.3e-11 43.6 0.0 2.5 3 0 0 3 3 3 2 PA domain Nup96 PF12110.8 KDO31460.1 - 0.028 13.5 0.2 0.046 12.8 0.2 1.3 1 0 0 1 1 1 0 Nuclear protein 96 XPA_C PF05181.12 KDO31461.1 - 0.0031 17.4 0.1 0.012 15.5 0.1 2.0 1 1 0 1 1 1 1 XPA protein C-terminus F-box-like PF12937.7 KDO31461.1 - 0.0069 16.3 0.1 0.043 13.7 0.1 2.5 1 0 0 1 1 1 1 F-box-like Phage_int_SAM_5 PF13102.6 KDO31461.1 - 0.025 14.9 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 Phage integrase SAM-like domain Zip PF02535.22 KDO31462.1 - 2.1e-28 99.6 18.2 6.4e-28 97.9 18.2 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Pro_isomerase PF00160.21 KDO31463.1 - 1.8e-36 125.8 0.0 2.6e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pannexin_like PF12534.8 KDO31463.1 - 1.2 8.2 2.3 1.6 7.8 2.3 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 NDK PF00334.19 KDO31464.1 - 1.4e-62 209.6 0.0 2.5e-35 121.4 0.0 3.5 3 0 0 3 3 3 3 Nucleoside diphosphate kinase ADK PF00406.22 KDO31464.1 - 2.2e-16 60.3 0.0 2.9e-08 33.9 0.0 4.2 4 0 0 4 4 4 3 Adenylate kinase AAA_17 PF13207.6 KDO31464.1 - 3.5e-05 24.3 0.0 0.029 14.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain Dpy-30 PF05186.13 KDO31464.1 - 0.015 15.0 0.4 0.041 13.6 0.4 1.7 1 0 0 1 1 1 0 Dpy-30 motif SMC_N PF02463.19 KDO31464.1 - 1.4 8.3 2.8 1.5 8.2 1.1 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1445 PF07286.12 KDO31465.1 - 4.1e-67 224.6 0.0 5.3e-67 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Mito_carr PF00153.27 KDO31466.1 - 2e-31 107.8 5.1 1.8e-14 53.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_2 PF07719.17 KDO31467.1 - 0.00038 20.3 3.0 0.0082 16.2 0.4 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31467.1 - 0.00064 19.7 0.2 0.59 10.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31467.1 - 0.00064 19.4 0.1 0.42 10.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO31467.1 - 0.0037 17.5 4.3 0.087 13.1 0.8 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat Methyltransf_21 PF05050.12 KDO31467.1 - 0.004 17.2 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain TPR_19 PF14559.6 KDO31467.1 - 0.068 13.7 0.4 0.068 13.7 0.4 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31467.1 - 2.6 9.1 15.4 0.46 11.4 0.6 4.4 3 2 2 5 5 5 0 Tetratricopeptide repeat RWP-RK PF02042.15 KDO31468.1 - 1.2e-18 66.8 0.1 2.6e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 KDO31468.1 - 2.2e-11 43.8 1.1 2.9e-11 43.4 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO31468.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain NAP PF00956.18 KDO31468.1 - 0.092 11.9 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) COX5B PF01215.19 KDO31469.1 - 7.2e-12 45.1 0.0 8.4e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb 4HBT PF03061.22 KDO31470.1 - 1.2e-08 35.2 0.0 3.8e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT PF03061.22 KDO31471.1 - 8.7e-07 29.2 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily GIT_SHD PF08518.11 KDO31471.1 - 0.3 10.8 1.2 17 5.1 0.2 2.5 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT Elicitin PF00964.17 KDO31472.1 - 8.5e-08 32.2 1.0 1.4e-07 31.5 1.0 1.4 1 0 0 1 1 1 1 Elicitin DUF5572 PF17733.1 KDO31472.1 - 0.22 11.4 3.2 0.28 11.1 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5572) CAF1A PF12253.8 KDO31473.1 - 5.2e-22 77.8 1.7 5.2e-22 77.8 1.7 2.6 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A TauE PF01925.19 KDO31476.1 - 1.9e-28 99.7 22.1 4.1e-15 56.1 6.9 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF563 PF04577.14 KDO31477.1 - 1.5e-27 97.1 0.0 2.3e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) AAA_18 PF13238.6 KDO31478.1 - 2.3e-29 102.6 0.0 3.4e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KDO31478.1 - 3.4e-09 37.2 0.1 1e-08 35.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KDO31478.1 - 6.4e-06 26.2 0.1 1.3e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 NTPase AAA PF00004.29 KDO31478.1 - 1.1e-05 25.8 0.6 3.1e-05 24.4 0.1 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KDO31478.1 - 5.2e-05 23.4 0.0 0.00036 20.7 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 KDO31478.1 - 0.00011 22.4 0.2 0.0083 16.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KDO31478.1 - 0.00016 21.9 0.0 0.00066 20.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KDO31478.1 - 0.00037 20.0 0.0 0.00069 19.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RuvB_N PF05496.12 KDO31478.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 KDO31478.1 - 0.00096 19.1 0.6 0.59 9.9 0.1 2.3 1 1 0 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 KDO31478.1 - 0.0019 18.5 1.6 0.014 15.7 1.6 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO31478.1 - 0.0038 17.6 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KDO31478.1 - 0.0048 16.6 0.0 0.0065 16.2 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase ATPase PF06745.13 KDO31478.1 - 0.0057 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC Thymidylate_kin PF02223.17 KDO31478.1 - 0.0063 16.2 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase RNA_helicase PF00910.22 KDO31478.1 - 0.0066 16.8 0.1 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KDO31478.1 - 0.0081 15.9 0.0 0.035 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KDO31478.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KDO31478.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KDO31478.1 - 0.012 15.6 0.1 0.025 14.6 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KDO31478.1 - 0.014 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 KDO31478.1 - 0.019 14.8 0.0 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.22 KDO31478.1 - 0.02 15.0 0.2 0.038 14.1 0.2 1.7 1 1 0 1 1 1 0 Shikimate kinase Sigma54_activ_2 PF14532.6 KDO31478.1 - 0.03 14.4 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_26 PF13500.6 KDO31478.1 - 0.034 14.0 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO31478.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KDO31478.1 - 0.037 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_3 PF07726.11 KDO31478.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KDO31478.1 - 0.053 12.4 0.4 0.19 10.6 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KDO31478.1 - 0.057 12.4 0.2 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KDO31478.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KDO31478.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KDO31478.1 - 0.083 13.2 3.6 0.18 12.1 3.6 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO31478.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KDO31478.1 - 0.084 13.0 0.1 0.17 12.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 KDO31478.1 - 0.091 12.5 0.5 0.091 12.5 0.5 2.1 2 1 1 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 KDO31478.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family Mg_chelatase PF01078.21 KDO31478.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 KDO31478.1 - 0.13 12.0 0.2 0.43 10.3 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KDO31478.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KDO31478.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase HlyU PF10115.9 KDO31483.1 - 0.027 14.5 0.2 0.072 13.2 0.4 1.6 2 0 0 2 2 2 0 Transcriptional activator HlyU AP1AR PF15745.5 KDO31483.1 - 0.029 14.0 2.3 0.035 13.7 2.3 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF4558 PF15104.6 KDO31483.1 - 0.056 13.5 6.0 0.093 12.8 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) SOBP PF15279.6 KDO31483.1 - 0.6 10.7 5.8 0.67 10.5 5.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein NIF PF03031.18 KDO31485.1 - 3e-33 114.8 0.0 4.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase JAB PF01398.21 KDO31486.1 - 1.9e-10 40.7 0.0 3.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KDO31486.1 - 3.1e-07 30.2 0.1 8.8e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3408 PF11888.8 KDO31486.1 - 2.3 8.4 4.6 2.6 8.2 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) PWWP PF00855.17 KDO31488.1 - 1.5e-11 44.5 0.0 3.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 PWWP domain LRR_4 PF12799.7 KDO31489.1 - 2.3e-07 31.0 0.6 5 7.7 0.0 5.7 4 3 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO31489.1 - 9.9e-06 25.2 0.0 54 4.2 0.0 6.9 7 0 0 7 7 7 1 Leucine Rich repeat IFT81_CH PF18383.1 KDO31490.1 - 4e-35 120.7 0.1 4e-35 120.7 0.1 2.7 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Laminin_II PF06009.12 KDO31490.1 - 0.0084 16.1 2.4 0.0084 16.1 2.4 5.6 4 2 2 6 6 6 3 Laminin Domain II BLOC1_2 PF10046.9 KDO31490.1 - 0.013 15.8 2.3 0.013 15.8 2.3 7.2 6 2 1 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 KDO31490.1 - 0.016 15.0 3.8 0.016 15.0 3.8 6.3 3 2 2 6 6 6 0 Phage minor structural protein GP20 PEP-utilisers_N PF05524.13 KDO31490.1 - 1.3 9.2 16.3 0.54 10.4 4.8 3.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Lzipper-MIP1 PF14389.6 KDO31490.1 - 4.8 7.6 35.1 0.5 10.7 1.7 5.3 5 0 0 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 Acyl-CoA_dh_C PF12806.7 KDO31490.1 - 5.5 7.2 6.5 1.3 9.2 0.1 3.2 4 0 0 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like Fic PF02661.18 KDO31490.1 - 8.1 7.4 8.3 6.4 7.7 0.3 3.8 1 1 4 5 5 5 0 Fic/DOC family Rep_fac-A_3 PF08661.11 KDO31491.1 - 4.7e-19 68.7 0.0 4.9e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 CLAMP PF14769.6 KDO31492.1 - 1.2e-23 83.4 0.2 1.8e-23 82.8 0.2 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 2-oxoacid_dh PF00198.23 KDO31493.1 - 5.6e-70 235.4 0.0 7e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KDO31493.1 - 2.1e-15 56.3 0.1 4.3e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KDO31493.1 - 4.9e-05 23.1 0.5 0.011 15.5 0.0 3.1 3 0 0 3 3 3 2 Biotin-lipoyl like Pkinase PF00069.25 KDO31494.1 - 1.5e-68 231.1 0.0 2.1e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31494.1 - 1.3e-53 181.9 0.0 1.8e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO31494.1 - 4.7e-07 28.9 0.0 8.2e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO31494.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO31494.1 - 0.047 12.6 0.0 0.69 8.8 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Vps35 PF03635.17 KDO31495.1 - 2.5e-201 671.0 0.2 3e-201 670.7 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TnsD PF15978.5 KDO31495.1 - 0.0018 17.3 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Tn7-like transposition protein D Rieske PF00355.26 KDO31498.1 - 1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Lar_N PF09861.9 KDO31499.1 - 1.1e-10 41.0 0.0 2.9e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Lactate racemase N-terminal domain Pyr_redox_2 PF07992.14 KDO31500.1 - 1.4e-37 129.5 0.0 1.9e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KDO31500.1 - 1.4e-26 92.9 0.3 1.7e-25 89.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KDO31500.1 - 1.2e-14 54.6 0.2 2.3e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO31500.1 - 3.2e-05 23.3 0.0 0.00064 19.1 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KDO31500.1 - 0.0053 16.7 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KDO31500.1 - 0.032 13.8 0.5 6.5 6.2 0.5 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KDO31500.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.16 KDO31501.1 - 2.2e-83 279.9 0.0 2.7e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Glucokinase Ribonuc_red_lgC PF02867.15 KDO31502.1 - 1.2e-184 614.7 0.0 1.5e-184 614.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KDO31502.1 - 2e-23 82.2 0.1 2.6e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KDO31502.1 - 1.7e-17 63.8 0.0 4.7e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Cyclin_N PF00134.23 KDO31504.1 - 9e-14 51.3 0.5 1.3e-12 47.6 0.0 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO31504.1 - 0.00088 19.3 3.9 0.0022 18.1 1.0 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain LSM PF01423.22 KDO31505.1 - 2.8e-05 23.7 0.6 2.8e-05 23.7 0.6 1.7 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 KDO31505.1 - 0.046 13.9 0.1 0.074 13.2 0.0 1.4 2 0 0 2 2 2 0 Ataxin 2 SM domain Cystatin PF00031.21 KDO31506.1 - 0.043 14.1 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Cystatin domain DUF1664 PF07889.12 KDO31507.1 - 2.2 8.4 11.3 2.7 8.1 1.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KDO31507.1 - 2.3 7.0 21.6 0.35 9.7 3.8 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein Disintegrin PF00200.23 KDO31508.1 - 8.6e-20 71.3 77.5 7.7e-05 23.4 3.7 7.7 5 4 1 6 6 6 6 Disintegrin DUF4246 PF14033.6 KDO31510.1 - 6.2e-14 51.9 0.0 1.3e-07 31.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) AIG1 PF04548.16 KDO31511.1 - 3.8e-07 29.6 0.0 7.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KDO31511.1 - 9.1e-07 29.0 0.0 9.1e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO31511.1 - 0.00087 19.6 0.0 0.0032 17.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.18 KDO31511.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 KDO31511.1 - 0.012 16.1 1.3 0.027 14.9 0.0 2.3 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KDO31511.1 - 0.019 14.8 1.5 0.029 14.3 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KDO31511.1 - 0.027 14.8 0.0 0.027 14.8 0.0 3.1 2 2 0 2 2 1 0 AAA ATPase domain AAA_24 PF13479.6 KDO31511.1 - 0.068 12.9 0.0 0.068 12.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KDO31511.1 - 0.077 13.2 0.1 0.077 13.2 0.1 3.3 2 2 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KDO31511.1 - 0.086 13.4 0.0 0.32 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO31511.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Borrelia_P83 PF05262.11 KDO31511.1 - 0.23 9.9 30.9 0.36 9.3 30.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_19 PF13245.6 KDO31511.1 - 0.58 10.5 0.0 0.58 10.5 0.0 2.8 2 1 0 2 2 1 0 AAA domain SAPS PF04499.15 KDO31511.1 - 4.2 6.1 8.8 5.8 5.6 8.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ank_2 PF12796.7 KDO31512.1 - 7.4e-21 74.5 1.9 1.4e-10 41.6 0.0 5.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31512.1 - 2.7e-16 59.7 8.1 7.4e-07 29.6 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31512.1 - 1.1e-15 57.5 3.1 0.00017 21.8 0.1 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO31512.1 - 1.1e-15 57.3 10.6 0.0016 18.8 0.3 7.4 6 2 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KDO31512.1 - 2.4e-12 45.9 9.8 0.0046 17.3 0.0 7.1 8 1 0 8 8 8 3 Ankyrin repeat Ank_2 PF12796.7 KDO31514.1 - 5.9e-09 36.4 2.6 0.0028 18.2 0.3 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31514.1 - 4.6e-07 30.3 9.6 0.11 13.1 0.1 5.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31514.1 - 1.2e-06 28.7 4.6 0.47 10.8 0.0 6.2 2 2 4 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31514.1 - 0.00043 20.5 4.9 57 4.8 0.0 6.7 6 1 1 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 KDO31515.1 - 1.3e-10 41.7 3.1 0.0003 21.3 0.0 4.3 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31515.1 - 9.8e-08 32.4 8.6 0.034 14.7 0.0 5.9 4 2 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31515.1 - 0.011 16.2 8.4 51 4.9 0.0 7.2 8 2 0 8 8 8 0 Ankyrin repeat DUF1418 PF07214.12 KDO31516.1 - 0.24 11.2 1.9 0.42 10.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) MARVEL PF01284.23 KDO31516.1 - 4.4 7.3 18.9 5.5 7.0 17.6 1.7 1 1 1 2 2 2 0 Membrane-associating domain MORN PF02493.20 KDO31518.1 - 8.1e-37 123.0 39.1 2.7e-06 26.9 0.2 11.1 11 0 0 11 11 11 8 MORN repeat Kelch_3 PF13415.6 KDO31518.1 - 3.6e-15 55.8 1.9 0.00011 22.3 0.0 6.7 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KDO31518.1 - 1.2e-11 44.4 0.1 0.094 12.7 0.0 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO31518.1 - 4e-10 39.4 0.0 0.57 10.2 0.0 6.9 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KDO31518.1 - 5.2e-06 26.2 0.0 0.27 11.3 0.0 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 KDO31518.1 - 6.3e-05 22.5 1.0 7.1 6.3 0.0 6.0 7 0 0 7 7 7 1 Kelch motif Qn_am_d_aII PF14930.6 KDO31518.1 - 0.047 14.0 1.2 0.13 12.6 1.2 1.8 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Pkinase PF00069.25 KDO31519.1 - 1.1e-71 241.2 0.0 1.4e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31519.1 - 3e-34 118.5 0.0 4.2e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO31519.1 - 0.00016 20.7 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO31519.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO31519.1 - 0.0026 17.1 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 KDO31520.1 - 8.1e-05 22.8 0.0 0.23 11.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PDZ PF00595.24 KDO31520.1 - 0.0087 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ank_3 PF13606.6 KDO31520.1 - 0.021 15.3 0.2 14 6.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat PDZ_6 PF17820.1 KDO31520.1 - 0.026 14.4 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Ank_4 PF13637.6 KDO31520.1 - 0.03 14.9 0.0 0.088 13.4 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31520.1 - 0.032 14.8 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KDO31520.1 - 0.082 13.4 0.6 17 6.1 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat Sigma_M_inh PF17453.2 KDO31520.1 - 0.084 13.3 0.1 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-M inhibitor ABC_tran PF00005.27 KDO31521.1 - 7.5e-24 84.8 0.0 1.3e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KDO31521.1 - 1.6e-16 60.4 16.9 1.6e-16 60.4 16.9 2.1 2 1 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KDO31521.1 - 7.6e-07 29.2 3.5 0.0031 17.4 0.4 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO31521.1 - 0.0014 18.1 0.0 0.88 9.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO31521.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KDO31521.1 - 0.0048 16.6 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO31521.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO31521.1 - 0.0072 16.7 0.3 0.017 15.5 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KDO31521.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO31521.1 - 0.019 15.3 0.1 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO31521.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KDO31521.1 - 0.022 14.3 0.1 0.054 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KDO31521.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 KDO31521.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 KDO31521.1 - 0.16 12.6 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ferrochelatase PF00762.19 KDO31522.1 - 7.5e-106 353.8 0.0 8.7e-106 353.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 KDO31522.1 - 1.7e-05 25.1 0.0 0.011 16.1 0.0 3.0 3 0 0 3 3 3 2 CbiX EF-hand_7 PF13499.6 KDO31523.1 - 3.1e-16 59.6 0.0 5.8e-08 33.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO31523.1 - 1.1e-15 55.9 0.6 4.6e-07 28.9 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO31523.1 - 1.9e-13 49.2 0.0 8.2e-05 22.2 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KDO31523.1 - 1.5e-11 43.9 0.0 5.5e-09 35.7 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO31523.1 - 1.3e-08 34.0 2.8 1.9e-06 27.1 0.1 3.7 4 0 0 4 4 4 1 EF hand EF-hand_10 PF14788.6 KDO31523.1 - 0.0013 18.5 0.1 0.51 10.2 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KDO31523.1 - 0.0023 18.2 0.1 0.016 15.5 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KDO31523.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_11 PF08976.11 KDO31523.1 - 0.053 14.4 0.0 0.33 11.9 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain PfkB PF00294.24 KDO31525.1 - 1.6e-24 86.8 0.1 2.6e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SIS PF01380.22 KDO31525.1 - 1.1e-18 67.3 0.0 3.9e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 KDO31525.1 - 1.7e-06 28.1 0.0 0.1 12.6 0.0 2.9 1 1 1 2 2 2 2 SIS domain BmKX PF09132.10 KDO31526.1 - 9.6 6.3 8.1 0.53 10.3 0.2 2.8 3 0 0 3 3 3 0 BmKX TAF4 PF05236.14 KDO31527.1 - 0.04 13.7 6.7 0.062 13.0 6.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Vasohibin PF14822.6 KDO31527.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Vasohibin Il2rg PF15874.5 KDO31528.1 - 0.00047 20.4 0.3 0.0022 18.2 0.0 2.0 2 1 0 2 2 2 1 Putative Interleukin 2 receptor, gamma chain Chalcone_3 PF16036.5 KDO31528.1 - 0.014 15.5 0.1 0.017 15.2 0.1 1.1 1 0 0 1 1 1 0 Chalcone isomerase-like Adhesin_P1_N PF18652.1 KDO31528.1 - 0.038 14.0 0.5 0.086 12.9 0.2 1.7 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain Apt1 PF10351.9 KDO31528.1 - 0.12 11.2 0.3 0.14 11.0 0.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NMT1 PF09084.11 KDO31529.1 - 1.1e-67 228.2 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KDO31529.1 - 0.00024 20.9 0.1 0.003 17.3 0.0 2.2 2 0 0 2 2 2 1 NMT1-like family FtsJ PF01728.19 KDO31530.1 - 3.4e-69 232.5 0.1 4e-69 232.3 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 KDO31531.1 - 1.3e-66 224.7 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31531.1 - 3.3e-28 98.7 0.1 5.8e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO31531.1 - 0.0016 17.8 0.0 0.0089 15.4 0.1 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO31531.1 - 0.018 14.6 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KDO31531.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AMP-binding PF00501.28 KDO31532.1 - 5.9e-42 143.7 0.0 8.3e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KDO31532.1 - 8.1e-09 35.3 0.7 1.9e-08 34.1 0.7 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KDO31532.1 - 0.00089 20.2 0.3 0.0023 18.9 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Put_Phosphatase PF06888.12 KDO31533.1 - 4.4e-38 131.0 0.0 5.8e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KDO31533.1 - 1.2e-08 35.6 1.1 2.2e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO31533.1 - 0.009 16.3 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ESX-1_EspG PF14011.6 KDO31533.1 - 0.26 10.9 10.1 3 7.4 6.1 2.1 2 0 0 2 2 2 0 EspG family LPG_synthase_TM PF03706.13 KDO31533.1 - 0.3 10.6 1.5 0.42 10.1 1.5 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region zf-CCCH PF00642.24 KDO31534.1 - 3.6e-11 42.7 14.6 7.1e-06 25.8 5.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO31534.1 - 1.3e-08 34.4 9.8 0.00081 19.1 0.1 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO31534.1 - 3.6e-08 33.2 12.6 0.00064 19.7 3.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KDO31534.1 - 0.0018 18.6 7.4 0.33 11.5 0.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KDO31534.1 - 0.0089 16.7 7.2 1.1 10.0 1.9 2.3 1 1 1 2 2 2 2 Torus domain zf-CCHH PF10283.9 KDO31534.1 - 0.6 10.1 8.1 5.2 7.2 1.0 2.6 2 0 0 2 2 2 0 PBZ domain oligo_HPY PF08352.12 KDO31534.1 - 2.2 8.8 6.6 11 6.6 0.6 2.5 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region RRM_1 PF00076.22 KDO31535.1 - 3.9e-29 100.3 0.0 2.4e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO31535.1 - 0.00049 19.9 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KDO31535.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KDO31535.1 - 0.029 14.4 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 KDO31535.1 - 0.032 14.3 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF2457 PF10446.9 KDO31535.1 - 0.076 12.1 22.1 0.018 14.2 19.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SPOR PF05036.13 KDO31535.1 - 0.078 13.4 0.0 0.3 11.5 0.0 2.0 1 1 0 1 1 1 0 Sporulation related domain LRR_8 PF13855.6 KDO31536.1 - 2.1e-47 158.7 65.9 3.8e-09 36.2 6.2 9.7 7 2 3 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KDO31536.1 - 8.7e-38 127.7 65.4 0.00012 22.3 3.0 11.6 5 3 7 13 13 13 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO31536.1 - 2.5e-15 56.4 22.8 3.6e-05 23.4 3.8 6.1 2 2 5 7 7 7 7 Leucine-rich repeat LRR_1 PF00560.33 KDO31536.1 - 5.8e-07 29.2 49.6 2.8 8.9 2.9 15.3 15 2 0 15 15 15 3 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KDO31536.1 - 0.029 14.4 0.4 11 6.1 0.0 4.1 4 1 0 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KDO31536.1 - 0.23 11.6 60.4 0.75 10.0 1.0 13.5 15 0 0 15 15 15 0 Leucine Rich repeat RRM_1 PF00076.22 KDO31537.1 - 1.1e-23 82.8 0.9 4.3e-06 26.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO31537.1 - 9.8e-06 25.3 0.3 0.2 11.5 0.1 3.0 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KDO31537.1 - 0.0019 18.0 0.0 0.059 13.2 0.0 2.3 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KDO31537.1 - 0.027 14.6 0.1 3 8.0 0.0 3.2 2 1 0 2 2 2 0 RNA recognition motif TmoB PF06234.12 KDO31537.1 - 0.097 12.8 1.3 0.41 10.7 0.0 2.6 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) DUF4777 PF16007.5 KDO31538.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) SURNod19 PF07712.12 KDO31539.1 - 1.2e-46 159.2 6.2 5.4e-45 153.8 6.2 2.8 1 1 0 1 1 1 1 Stress up-regulated Nod 19 Peptidase_C1 PF00112.23 KDO31540.1 - 1.6e-41 142.8 3.1 2.1e-41 142.4 3.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO31540.1 - 0.026 13.3 0.8 0.04 12.7 0.8 1.1 1 0 0 1 1 1 0 Peptidase C1-like family QRPTase_C PF01729.19 KDO31541.1 - 2e-56 190.4 0.0 2.6e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KDO31541.1 - 1.7e-16 60.0 0.0 6.3e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Acetyltransf_3 PF13302.7 KDO31543.1 - 1.2e-13 51.9 0.1 1.5e-13 51.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KDO31543.1 - 8.1e-08 32.5 0.0 9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO31543.1 - 4.2e-06 27.0 0.0 5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4349 PF14257.6 KDO31544.1 - 0.02 14.3 2.5 0.027 13.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) PDZ_6 PF17820.1 KDO31544.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Pro_isomerase PF00160.21 KDO31545.1 - 7.6e-39 133.5 0.2 1e-38 133.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_5 PF13857.6 KDO31546.1 - 5.6e-16 58.4 1.6 1.3e-06 28.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31546.1 - 5.7e-15 55.7 1.1 2.6e-07 31.1 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO31546.1 - 9.6e-13 47.1 0.8 0.018 15.5 0.0 5.5 7 0 0 7 7 6 3 Ankyrin repeat Ank_4 PF13637.6 KDO31546.1 - 4.2e-12 46.3 1.5 6.4e-05 23.4 0.0 4.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO31546.1 - 2.2e-10 40.5 0.8 0.0036 17.7 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat FYVE PF01363.21 KDO31546.1 - 4.5e-06 26.7 5.6 7.9e-06 25.9 5.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 KDO31546.1 - 8.4e-05 22.7 1.7 8.4e-05 22.7 1.7 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 2 DUF4428 PF14471.6 KDO31546.1 - 1.2 9.1 6.0 3.4 7.7 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.16 KDO31546.1 - 1.3 9.3 9.9 3.9 7.7 5.5 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger SR-25 PF10500.9 KDO31546.1 - 5.7 6.5 8.2 13 5.3 8.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zinc_ribbon_12 PF11331.8 KDO31546.1 - 9.2 6.2 8.0 1.2 9.0 0.1 2.8 2 1 0 2 2 2 0 Probable zinc-ribbon domain TFIIS_C PF01096.18 KDO31548.1 - 1.2e-17 63.4 2.5 1.2e-17 63.4 2.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) TF_Zn_Ribbon PF08271.12 KDO31548.1 - 8.4e-05 22.0 15.6 0.00028 20.3 3.5 3.3 2 1 1 3 3 3 1 TFIIB zinc-binding RNA_POL_M_15KD PF02150.16 KDO31548.1 - 0.00027 20.8 16.5 0.031 14.2 3.4 3.4 2 2 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 KDO31548.1 - 0.00041 20.3 14.3 0.001 19.0 3.1 2.9 2 1 0 2 2 2 1 Double zinc ribbon Lar_restr_allev PF14354.6 KDO31548.1 - 0.005 17.2 10.0 0.15 12.4 1.5 2.4 2 0 0 2 2 2 2 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 KDO31548.1 - 0.0061 16.5 15.6 0.028 14.4 1.2 3.2 2 1 0 2 2 2 1 Transposase zinc-ribbon domain C1_1 PF00130.22 KDO31548.1 - 0.0066 16.3 1.5 0.0066 16.3 1.5 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 KDO31548.1 - 0.016 14.6 20.1 0.14 11.6 5.9 4.1 3 1 1 4 4 4 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KDO31548.1 - 0.022 14.7 1.2 0.022 14.7 1.2 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Auto_anti-p27 PF06677.12 KDO31548.1 - 0.031 14.4 14.5 0.031 14.4 1.4 3.1 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KDO31548.1 - 0.033 14.1 0.8 0.033 14.1 0.8 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 PADR1 PF08063.12 KDO31548.1 - 0.034 13.9 10.1 1 9.2 0.2 3.1 3 0 0 3 3 3 0 PADR1 (NUC008) domain zinc_ribbon_2 PF13240.6 KDO31548.1 - 0.039 13.7 21.1 0.15 11.8 5.6 4.2 3 1 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.6 KDO31548.1 - 0.042 13.9 14.9 0.85 9.8 3.6 3.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-TFIIB PF13453.6 KDO31548.1 - 0.043 13.2 1.4 0.043 13.2 1.4 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.11 KDO31548.1 - 0.051 13.5 1.4 0.051 13.5 1.4 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Baculo_LEF5_C PF11792.8 KDO31548.1 - 0.073 12.8 0.0 0.073 12.8 0.0 2.9 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-C2H2_3 PF13878.6 KDO31548.1 - 0.12 12.3 10.9 0.81 9.6 0.2 4.0 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO RPA_interact_C PF14768.6 KDO31548.1 - 0.14 12.7 6.8 0.29 11.7 6.8 1.6 1 1 0 1 1 1 0 Replication protein A interacting C-terminal zf-RING_7 PF02591.15 KDO31548.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain tRNA-synt_1f PF01921.18 KDO31548.1 - 0.25 10.2 0.8 0.31 9.9 0.2 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) FYVE_2 PF02318.16 KDO31548.1 - 0.28 11.4 5.3 5.6 7.2 1.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 KDO31548.1 - 0.29 11.3 20.1 1.4 9.1 1.3 4.3 3 1 2 5 5 5 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KDO31548.1 - 0.43 10.6 12.9 6.1 6.9 0.3 4.1 3 1 0 3 3 3 0 zinc-ribbon domain GATA PF00320.27 KDO31548.1 - 0.43 10.2 9.1 3.2 7.4 0.5 3.5 3 0 0 3 3 3 0 GATA zinc finger HypA PF01155.19 KDO31548.1 - 0.48 10.5 10.8 13 5.9 5.5 3.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4379 PF14311.6 KDO31548.1 - 0.69 10.3 0.1 0.69 10.3 0.1 3.5 3 1 0 4 4 3 0 Probable Zinc-ribbon domain zinc_ribbon_9 PF14369.6 KDO31548.1 - 0.8 10.0 8.3 12 6.3 0.1 3.6 4 0 0 4 4 3 0 zinc-ribbon Nudix_N_2 PF14803.6 KDO31548.1 - 1.3 9.0 16.9 16 5.5 8.2 4.1 2 2 1 3 3 3 0 Nudix N-terminal zf-RRN7 PF11781.8 KDO31548.1 - 1.6 8.5 15.4 7.5 6.3 4.6 4.3 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rpr2 PF04032.16 KDO31548.1 - 1.6 9.1 8.4 0.95 9.8 0.1 2.8 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DNA_RNApol_7kD PF03604.13 KDO31548.1 - 2.5 7.8 15.9 0.49 10.1 1.4 2.7 3 0 0 3 3 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2HC5 PF06221.13 KDO31548.1 - 2.8 8.0 10.6 5.8 7.0 4.0 3.1 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Terminase_GpA PF05876.12 KDO31548.1 - 2.9 6.3 8.2 0.18 10.3 1.3 2.0 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) zf_UBZ PF18439.1 KDO31548.1 - 3.1 7.5 14.1 6.2 6.5 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF2387 PF09526.10 KDO31548.1 - 4.8 7.4 11.1 0.51 10.5 0.2 2.9 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.13 KDO31548.1 - 9.3 6.4 10.0 1.3 9.2 0.3 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-NADH-PPase PF09297.11 KDO31548.1 - 9.6 6.0 16.5 2.1 8.1 0.2 4.1 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain PSS PF03034.15 KDO31549.1 - 3e-101 338.8 13.7 4e-101 338.4 13.7 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase RCC1 PF00415.18 KDO31550.1 - 1.1e-64 214.9 9.5 2.5e-12 47.2 0.0 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KDO31550.1 - 3.2e-61 207.5 0.0 5.4e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 KDO31550.1 - 1.8e-32 110.4 28.5 2.4e-08 33.6 1.6 7.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 KDO31550.1 - 6.4e-18 65.0 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 KDO31550.1 - 2.2e-11 44.1 0.0 8.4e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 KDO31550.1 - 0.013 15.4 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain Cwf_Cwc_15 PF04889.12 KDO31550.1 - 0.8 9.4 13.4 1.4 8.6 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KDO31550.1 - 2.2 6.3 21.1 4 5.4 21.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KDO31550.1 - 7.4 4.6 12.5 12 4.0 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KDO31550.1 - 9.5 5.5 12.7 15 4.9 12.7 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 KDO31550.1 - 9.6 6.1 8.4 16 5.3 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 KDO31551.1 - 0.011 16.4 1.2 1.6 9.4 0.3 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31551.1 - 0.054 14.1 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) GCV_T PF01571.21 KDO31552.1 - 1.7e-64 217.7 0.0 2.4e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KDO31552.1 - 2.1e-55 188.7 1.2 3.1e-55 188.2 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KDO31552.1 - 3e-17 62.7 0.1 7.5e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KDO31552.1 - 2e-16 59.7 0.0 4.6e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.24 KDO31552.1 - 2.6e-06 26.8 2.6 7e-06 25.4 2.6 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KDO31552.1 - 7.8e-05 22.1 1.2 0.0035 16.6 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KDO31552.1 - 0.0011 18.2 2.3 0.029 13.6 0.3 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KDO31552.1 - 0.0038 16.5 0.2 0.035 13.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 KDO31552.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family NAD_binding_7 PF13241.6 KDO31552.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KDO31552.1 - 0.021 15.1 0.2 0.15 12.3 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thr_synth_N PF14821.6 KDO31552.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonine synthase N terminus GIDA PF01134.22 KDO31552.1 - 0.13 11.3 1.8 0.64 9.0 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A SmpB PF01668.18 KDO31553.1 - 2.1e-35 121.7 0.3 2.4e-35 121.5 0.3 1.0 1 0 0 1 1 1 1 SmpB protein VPS9 PF02204.18 KDO31554.1 - 1.6e-17 63.6 0.0 3.7e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 KDO31554.1 - 4.4e-05 23.4 0.4 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 PX domain CLZ PF16526.5 KDO31555.1 - 0.03 14.7 1.8 9 6.7 0.2 3.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels gpW PF02831.15 KDO31555.1 - 0.13 12.2 3.2 0.099 12.6 0.4 2.4 2 0 0 2 2 2 0 gpW DUF1664 PF07889.12 KDO31555.1 - 0.16 12.0 5.2 4.4 7.4 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) p25-alpha PF05517.12 KDO31555.1 - 0.2 11.8 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 p25-alpha Fib_alpha PF08702.10 KDO31555.1 - 1.6 8.9 7.2 5.4 7.2 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_C26 PF07722.13 KDO31557.1 - 3.9e-24 85.6 0.0 8.9e-23 81.2 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 GATase PF00117.28 KDO31557.1 - 7e-13 48.8 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KDO31557.1 - 0.061 13.2 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 SNO glutamine amidotransferase family GRDP-like PF07173.12 KDO31558.1 - 3.4e-12 47.2 0.4 6.6e-12 46.3 0.4 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like GRDP-like PF07173.12 KDO31559.1 - 8.5e-13 49.2 0.3 1.6e-12 48.2 0.3 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like GATA PF00320.27 KDO31559.1 - 0.031 13.9 1.2 0.089 12.4 1.2 1.8 1 0 0 1 1 1 0 GATA zinc finger DUF4451 PF14616.6 KDO31559.1 - 0.17 12.1 0.6 1.8 8.8 0.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) G8 PF10162.9 KDO31560.1 - 1.7e-11 44.3 0.0 3.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 KDO31560.1 - 0.00033 20.5 7.3 0.0035 17.2 1.0 3.9 3 2 1 4 4 4 2 Right handed beta helix region ADH_N_assoc PF13823.6 KDO31560.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ASH PF15780.5 KDO31561.1 - 0.00072 19.7 0.2 2.6 8.3 0.0 3.5 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SIP1 PF04938.12 KDO31562.1 - 5.3e-33 114.6 0.0 7.7e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) AAA_lid_7 PF17867.1 KDO31562.1 - 0.0022 18.2 0.3 0.0039 17.4 0.3 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain NADH_Oxid_Nqo15 PF11497.8 KDO31562.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 HGTP_anticodon2 PF12745.7 KDO31562.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SR-25 PF10500.9 KDO31563.1 - 0.065 12.8 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1772 PF08592.11 KDO31564.1 - 2.7e-16 60.1 3.5 3.4e-16 59.8 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Prd1-P2 PF09214.11 KDO31564.1 - 0.086 11.6 0.1 0.096 11.4 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 Kinesin PF00225.23 KDO31565.1 - 2.3e-117 391.6 0.2 2.3e-117 391.6 0.2 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO31565.1 - 5.5e-28 97.8 0.1 5.5e-28 97.8 0.1 2.8 2 1 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KDO31565.1 - 0.0031 17.7 5.5 0.0031 17.7 5.5 3.7 1 1 2 3 3 3 1 Kinesin-associated DUF5104 PF17117.5 KDO31565.1 - 0.049 14.1 4.5 1.6 9.2 0.1 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5104) Cyto_heme_lyase PF01265.17 KDO31566.1 - 3.2e-58 197.6 3.9 1.3e-57 195.6 3.9 1.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF423 PF04241.15 KDO31568.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF423) STT3 PF02516.14 KDO31569.1 - 5.6e-29 101.4 14.8 1.8e-27 96.4 14.8 2.7 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 KDO31570.1 - 2.9e-60 204.6 18.2 3.6e-60 204.3 18.2 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PDH_E1_M PF17831.1 KDO31570.1 - 0.05 13.1 2.9 0.079 12.5 2.9 1.3 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain FUSC_2 PF13515.6 KDO31570.1 - 2.5 8.3 16.5 2.5 8.2 12.7 2.4 2 1 0 2 2 2 0 Fusaric acid resistance protein-like Proteasome PF00227.26 KDO31571.1 - 3.7e-63 212.5 0.4 4.9e-63 212.1 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO31571.1 - 4.9e-15 54.9 0.1 9.9e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RCC1 PF00415.18 KDO31572.1 - 5.8e-60 199.7 13.8 3.5e-14 53.1 0.5 7.6 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO31572.1 - 6.7e-25 86.3 38.0 9.5e-09 34.8 1.8 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PA PF02225.22 KDO31572.1 - 2.3e-09 37.1 0.0 1.3e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 PA domain IQ PF00612.27 KDO31572.1 - 8.7e-05 22.0 0.0 0.00024 20.6 0.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_6 PF13405.6 KDO31572.1 - 0.0017 18.1 0.1 0.0052 16.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KDO31572.1 - 0.005 16.3 0.1 0.013 15.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO31572.1 - 0.021 15.3 0.0 0.064 13.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KDO31572.1 - 0.14 11.7 0.1 0.4 10.3 0.1 1.8 1 0 0 1 1 1 0 EF hand PP2C PF00481.21 KDO31573.1 - 8e-17 61.7 0.0 6.8e-08 32.4 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KDO31573.1 - 3.4e-09 36.6 0.0 2.2e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C P_proprotein PF01483.20 KDO31574.1 - 0.05 13.6 0.1 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Proprotein convertase P-domain YHYH PF14240.6 KDO31575.1 - 4.9e-24 85.4 3.3 2e-14 54.0 0.0 4.0 2 2 2 4 4 4 3 YHYH protein PIP5K PF01504.18 KDO31576.1 - 4.1e-40 137.7 0.7 2.3e-29 102.5 0.1 2.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KDO31576.1 - 4.3e-25 88.3 0.0 3.9e-24 85.2 0.0 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KDO31576.1 - 5.4e-13 48.9 11.6 5.4e-13 48.9 11.6 2.1 2 0 0 2 2 2 1 FYVE zinc finger PDZ_6 PF17820.1 KDO31576.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.17 KDO31577.1 - 4.5e-49 167.1 0.0 5.5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31577.1 - 1.6e-44 152.3 0.0 2.2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KDO31577.1 - 0.059 12.3 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain EphA2_TM PF14575.6 KDO31577.1 - 0.11 13.3 0.0 0.2 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 KDO31577.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FeoB_associated PF12669.7 KDO31577.1 - 0.2 12.1 3.1 0.38 11.2 3.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein RIFIN PF02009.16 KDO31577.1 - 0.51 10.2 1.5 0.75 9.6 0.6 1.7 2 0 0 2 2 2 0 Rifin GRA6 PF05084.13 KDO31577.1 - 1 9.2 3.0 2.3 8.1 3.0 1.6 1 1 0 1 1 1 0 Granule antigen protein (GRA6) Arch_flagellin PF01917.16 KDO31577.1 - 1.8 8.7 5.1 7.5 6.7 5.4 1.8 3 0 0 3 3 3 0 Archaebacterial flagellin DUF2749 PF10907.8 KDO31577.1 - 2.9 8.1 6.1 6.8 7.0 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) DUF1180 PF06679.12 KDO31577.1 - 3.4 8.0 6.4 1.8 9.0 4.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Cpn60_TCP1 PF00118.24 KDO31578.1 - 3.1e-29 102.0 0.0 8e-29 100.6 0.0 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAP_assoc PF03828.19 KDO31579.1 - 0.00012 22.2 2.5 0.00025 21.2 0.1 2.7 2 1 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KDO31579.1 - 0.00051 20.3 0.1 0.0017 18.6 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF5355 PF17306.2 KDO31579.1 - 0.14 11.2 0.4 0.2 10.7 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5355) ZapB PF06005.12 KDO31579.1 - 0.69 10.4 8.8 9.6 6.7 0.2 2.5 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KDO31579.1 - 4.9 7.6 8.4 5.5 7.4 0.4 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DASH_Dam1 PF08653.10 KDO31580.1 - 3.8e-07 29.8 0.0 8.9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4423 PF14394.6 KDO31580.1 - 0.31 10.7 2.0 0.56 9.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Actin PF00022.19 KDO31581.1 - 3.1e-82 276.4 0.0 1.1e-48 165.9 0.0 3.0 1 1 1 2 2 2 2 Actin Peptidase_C1 PF00112.23 KDO31582.1 - 2.3e-15 57.3 0.2 3.8e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease DUF3438 PF11920.8 KDO31583.1 - 0.037 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Metallophos PF00149.28 KDO31584.1 - 0.00084 19.9 0.1 0.0057 17.2 0.0 2.2 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase Bromodomain PF00439.25 KDO31585.1 - 1.3e-13 50.8 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain U1snRNP70_N PF12220.8 KDO31585.1 - 1.1 10.0 8.8 0.14 12.8 2.0 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DHHC PF01529.20 KDO31586.1 - 5.5e-28 97.7 22.6 2.7e-27 95.5 17.8 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ndc1_Nup PF09531.10 KDO31586.1 - 0.21 10.2 3.2 0.25 10.0 3.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HHH_8 PF14716.6 KDO31588.1 - 7.2e-15 55.1 0.8 1.4e-14 54.2 0.8 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PBP1_TM PF14812.6 KDO31588.1 - 0.098 13.0 5.1 0.22 11.9 5.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_H2_suC PF08615.11 KDO31588.1 - 0.11 12.7 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ORC4_C PF14629.6 KDO31589.1 - 1.1e-15 57.6 0.7 1.9e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KDO31589.1 - 1e-06 29.3 0.9 1e-06 29.3 0.9 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO31589.1 - 0.00019 21.7 0.1 0.00063 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KDO31589.1 - 0.0011 18.4 0.1 0.0032 16.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 KDO31589.1 - 0.003 17.5 0.1 0.0089 16.0 0.1 1.8 1 0 0 1 1 1 1 NACHT domain DUF815 PF05673.13 KDO31589.1 - 0.009 15.2 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KDO31589.1 - 0.023 13.9 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Ank_2 PF12796.7 KDO31590.1 - 4e-15 56.2 0.8 9.8e-07 29.3 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31590.1 - 7.1e-13 48.8 9.4 3.6e-06 27.4 0.2 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31590.1 - 1.2e-09 37.6 3.3 1.4 9.7 0.1 5.7 4 1 2 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KDO31590.1 - 7.3e-09 35.7 9.6 0.045 14.1 0.0 6.1 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO31590.1 - 2.5 8.7 7.1 39 4.9 0.4 4.4 3 2 1 4 4 4 0 Ankyrin repeat Pterin_bind PF00809.22 KDO31592.1 - 8.7e-66 222.1 1.0 2.7e-65 220.4 1.0 1.9 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KDO31592.1 - 1.7e-31 109.0 2.6 3.5e-31 108.0 0.0 2.8 2 1 1 3 3 3 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) XkdW PF09636.10 KDO31592.1 - 3 8.0 8.3 1.1 9.4 0.2 2.8 2 1 0 2 2 2 0 XkdW protein EGF_2 PF07974.13 KDO31593.1 - 0.0032 17.8 8.3 0.0032 17.8 8.3 6.8 7 1 0 7 7 7 3 EGF-like domain EGF PF00008.27 KDO31593.1 - 0.025 14.9 10.7 0.025 14.9 10.7 6.6 6 1 0 6 6 6 0 EGF-like domain EGF_3 PF12947.7 KDO31593.1 - 5.6 7.2 43.4 1.2 9.4 4.4 5.8 4 0 0 4 4 4 0 EGF domain EGF_2 PF07974.13 KDO31594.1 - 0.00048 20.4 27.3 0.00099 19.4 5.8 7.1 6 1 1 7 7 7 3 EGF-like domain EGF PF00008.27 KDO31594.1 - 0.00053 20.2 2.9 0.00053 20.2 2.9 6.3 6 1 0 6 6 6 3 EGF-like domain EGF_2 PF07974.13 KDO31596.1 - 0.022 15.1 9.3 0.022 15.1 9.3 6.7 6 1 0 6 6 6 0 EGF-like domain EGF PF00008.27 KDO31596.1 - 0.027 14.8 10.7 0.027 14.8 10.7 6.3 6 1 1 7 7 7 0 EGF-like domain EGF PF00008.27 KDO31597.1 - 0.00029 21.1 21.7 0.00052 20.3 2.9 6.4 6 1 0 6 6 6 3 EGF-like domain EGF_2 PF07974.13 KDO31597.1 - 0.00099 19.4 5.8 0.00099 19.4 5.8 7.1 6 1 1 7 7 7 3 EGF-like domain LSM PF01423.22 KDO31598.1 - 9.6e-18 63.6 0.2 1.1e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KDO31598.1 - 0.0042 16.7 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein RabGAP-TBC PF00566.18 KDO31599.1 - 4.7e-17 62.4 0.0 7.5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_S10 PF00450.22 KDO31600.1 - 6.2e-119 398.1 0.0 7.2e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase YchF-GTPase_C PF06071.13 KDO31601.1 - 2.9e-34 117.1 0.0 6.7e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KDO31601.1 - 2.5e-24 85.6 0.0 5.4e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KDO31601.1 - 6.5e-08 32.3 0.0 1.4e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KDO31601.1 - 0.0033 16.4 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KDO31601.1 - 0.037 14.6 0.0 0.096 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KDO31601.1 - 0.069 13.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KDO31601.1 - 0.089 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO31601.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KDO31601.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KDO31601.1 - 0.12 12.4 0.0 0.85 9.7 0.0 2.3 1 1 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 KDO31601.1 - 0.16 11.5 0.1 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zip PF02535.22 KDO31602.1 - 2.2e-36 125.7 0.0 2.8e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 KDO31602.1 - 0.21 11.3 4.6 3 7.5 0.4 2.7 2 0 0 2 2 2 0 Cation efflux family Asp PF00026.23 KDO31603.1 - 1.1e-22 80.9 0.3 1.9e-22 80.1 0.3 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO31603.1 - 1.4e-15 58.0 1.6 2.2e-15 57.3 1.6 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO31603.1 - 2e-13 50.4 0.0 5.3e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Myb_DNA-binding PF00249.31 KDO31604.1 - 7.1e-10 38.9 0.1 1.2e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO31604.1 - 0.0027 17.5 0.1 0.0041 17.0 0.1 1.2 1 0 0 1 1 1 1 Myb DNA-binding like CTU2 PF10288.9 KDO31604.1 - 0.011 16.0 0.4 0.018 15.3 0.4 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 WES_acyltransf PF03007.16 KDO31604.1 - 0.025 14.4 0.3 0.033 14.0 0.3 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Myb_DNA-bind_6 PF13921.6 KDO31604.1 - 0.05 13.9 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain PutA_N PF18083.1 KDO31604.1 - 0.085 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Proline utilization A N-terminal domain Erf4 PF10256.9 KDO31607.1 - 3e-07 30.5 0.0 4.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family IBN_N PF03810.19 KDO31608.1 - 1.9e-09 37.3 3.2 1.9e-09 37.3 0.4 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.11 KDO31608.1 - 0.031 13.5 3.4 0.032 13.4 0.5 2.4 2 1 1 3 3 3 0 CRM1 C terminal Peptidase_S10 PF00450.22 KDO31609.1 - 1.5e-117 393.6 0.1 1.7e-117 393.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KDO31610.1 - 2e-125 419.5 0.0 2.4e-125 419.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3895 PF13034.6 KDO31610.1 - 0.0065 16.4 0.5 0.018 15.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3895) Apo-CII PF05355.11 KDO31610.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Apolipoprotein C-II Peptidase_S10 PF00450.22 KDO31611.1 - 1.4e-110 370.6 0.0 1.7e-110 370.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KDO31612.1 - 1.9e-121 406.4 0.0 2.2e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-C3HC4_3 PF13920.6 KDO31615.1 - 5.2e-05 23.0 14.9 0.0002 21.1 14.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO31615.1 - 0.0059 16.4 11.4 0.026 14.4 11.4 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Carboxyl_trans PF01039.22 KDO31616.1 - 1.4e-140 469.2 0.0 8.6e-140 466.6 0.0 1.9 1 1 0 1 1 1 1 Carboxyl transferase domain SOG2 PF10428.9 KDO31616.1 - 0.083 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ECH_1 PF00378.20 KDO31616.1 - 0.55 9.5 2.0 0.46 9.7 0.1 1.8 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase MPC PF03650.13 KDO31617.1 - 5.5e-37 126.3 0.2 6e-37 126.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Glyco_hydro_30 PF02055.16 KDO31618.1 - 7.4e-86 288.3 1.2 9.8e-86 287.9 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 KDO31618.1 - 7e-13 48.9 4.4 3.9e-12 46.5 0.7 2.6 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 KDO31618.1 - 8.5e-10 38.7 1.1 1.5e-09 37.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain RicinB_lectin_2 PF14200.6 KDO31618.1 - 1.7e-06 28.6 0.5 5.5e-06 27.0 0.2 2.0 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_59 PF02057.15 KDO31618.1 - 6.5e-05 22.3 0.1 0.00014 21.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 DNA_pol3_a_NII PF11490.8 KDO31618.1 - 0.091 12.7 0.3 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Glyco_hydro_30 PF02055.16 KDO31619.1 - 6.5e-86 288.4 0.6 8.6e-86 288.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 KDO31619.1 - 9.2e-16 58.3 8.3 1.5e-12 47.8 1.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 KDO31619.1 - 1.4e-08 34.8 1.3 2.5e-08 34.0 0.1 2.0 3 0 0 3 3 3 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KDO31619.1 - 2.4e-06 27.0 0.0 4.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 RicinB_lectin_2 PF14200.6 KDO31619.1 - 0.0046 17.7 0.4 0.032 14.9 0.2 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 KDO31619.1 - 0.047 13.3 0.0 8.2 5.9 0.0 2.2 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 Methyltransf_16 PF10294.9 KDO31620.1 - 2.8e-30 105.3 0.0 3.7e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KDO31620.1 - 0.00055 19.8 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO31620.1 - 0.00077 19.3 0.1 0.0047 16.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO31620.1 - 0.16 12.7 0.1 0.73 10.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KDO31621.1 - 1.4e-64 217.7 0.4 4.3e-42 144.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KDO31621.1 - 1.3e-12 48.3 0.1 5.2e-07 30.3 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KDO31621.1 - 3.7e-11 43.5 0.1 3.7e-06 27.5 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KDO31621.1 - 9.4e-10 38.2 1.0 1.9e-05 24.2 0.1 2.3 1 1 1 2 2 2 2 Putative methyltransferase Ubie_methyltran PF01209.18 KDO31621.1 - 8.2e-07 28.6 0.2 6.2e-06 25.7 0.1 2.1 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 KDO31621.1 - 6.3e-06 26.0 0.3 0.001 18.8 0.1 2.3 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 KDO31621.1 - 6.3e-06 26.9 0.0 0.0019 18.9 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KDO31621.1 - 7.1e-06 25.9 0.8 0.0016 18.3 0.1 2.2 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KDO31621.1 - 0.00012 21.9 0.2 0.017 14.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 KDO31621.1 - 0.00015 21.6 2.5 0.28 11.0 0.1 2.9 2 2 2 4 4 4 2 PRMT5 arginine-N-methyltransferase NodS PF05401.11 KDO31621.1 - 0.00026 20.7 0.2 0.0041 16.8 0.1 2.1 1 1 1 2 2 2 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 KDO31621.1 - 0.0004 20.3 0.0 0.0013 18.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO31621.1 - 0.00049 19.8 0.3 0.42 10.2 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KDO31621.1 - 0.00051 19.7 0.3 0.23 11.0 0.0 2.5 2 1 1 3 3 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KDO31621.1 - 0.0011 18.9 0.7 0.32 10.9 0.1 2.5 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_5 PF01795.19 KDO31621.1 - 0.0018 17.8 0.2 0.27 10.7 0.0 2.1 1 1 1 2 2 2 2 MraW methylase family Strep_his_triad PF04270.13 KDO31621.1 - 0.0027 17.7 2.7 1.1 9.3 0.1 2.6 3 0 0 3 3 2 2 Streptococcal histidine triad protein Met_10 PF02475.16 KDO31621.1 - 0.0051 16.6 1.2 0.89 9.3 0.1 2.2 1 1 1 2 2 2 2 Met-10+ like-protein TrkA_N PF02254.18 KDO31621.1 - 0.0092 16.2 2.1 1 9.6 0.1 2.5 1 1 1 2 2 2 1 TrkA-N domain MTS PF05175.14 KDO31621.1 - 0.037 13.6 0.3 0.44 10.1 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase small domain DREV PF05219.12 KDO31621.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_3 PF01596.17 KDO31621.1 - 0.13 11.4 1.0 0.59 9.3 0.6 2.1 2 1 0 2 2 2 0 O-methyltransferase ATP-synt_G PF04718.15 KDO31621.1 - 0.23 12.3 1.8 6.1 7.7 0.1 2.7 2 1 1 3 3 2 0 Mitochondrial ATP synthase g subunit DUF43 PF01861.16 KDO31621.1 - 0.25 10.5 1.7 4.7 6.3 0.1 2.1 1 1 1 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain DUF4347 PF14252.6 KDO31621.1 - 0.57 10.0 2.6 9.9 6.0 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4347) SPOB_a PF14689.6 KDO31621.1 - 3.5 7.4 5.2 23 4.8 0.3 3.1 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Big_2 PF02368.18 KDO31623.1 - 0.16 11.9 3.6 0.31 10.9 0.2 2.2 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 2) Ribosomal_L11 PF00298.19 KDO31624.1 - 4.3e-26 91.2 0.0 6.8e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KDO31624.1 - 1.1e-25 89.3 0.0 1.7e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Mis12 PF05859.12 KDO31625.1 - 5.3e-17 62.1 1.1 7.2e-17 61.7 1.1 1.2 1 0 0 1 1 1 1 Mis12 protein Filament PF00038.21 KDO31625.1 - 0.0015 18.1 0.6 0.0015 18.1 0.6 1.4 2 0 0 2 2 2 1 Intermediate filament protein DUF3450 PF11932.8 KDO31625.1 - 0.0031 16.9 2.1 0.0053 16.1 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4376 PF14301.6 KDO31625.1 - 0.013 15.8 5.4 0.02 15.2 4.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) THOC7 PF05615.13 KDO31625.1 - 0.034 14.4 4.1 0.1 12.9 4.1 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 DivIC PF04977.15 KDO31625.1 - 1.6 8.5 5.6 0.25 11.1 1.5 1.8 2 0 0 2 2 2 0 Septum formation initiator Exo_endo_phos PF03372.23 KDO31626.1 - 3.6e-14 52.9 0.1 5.8e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC_membrane PF00664.23 KDO31627.1 - 4.1e-55 187.3 1.8 5.2e-55 187.0 1.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KDO31627.1 - 4.3e-30 105.0 0.0 8.8e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KDO31627.1 - 2e-08 33.9 0.6 2.8e-06 27.0 0.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KDO31627.1 - 0.00035 20.5 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KDO31627.1 - 0.00046 20.5 0.2 0.0037 17.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO31627.1 - 0.00056 20.3 0.1 0.0018 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KDO31627.1 - 0.0014 19.0 0.7 0.055 13.9 0.7 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KDO31627.1 - 0.0021 17.8 0.2 0.0089 15.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KDO31627.1 - 0.0094 14.8 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 KDO31627.1 - 0.011 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO31627.1 - 0.036 14.0 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KDO31627.1 - 0.059 13.1 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KDO31627.1 - 0.11 12.7 0.6 0.75 10.1 0.6 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KDO31627.1 - 0.14 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KDO31627.1 - 0.17 12.4 0.1 1 9.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain DUF1853 PF08907.11 KDO31628.1 - 5.5e-39 134.6 0.3 9.5e-39 133.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1853) DNA_pol_A_exo1 PF01612.20 KDO31628.1 - 5.4e-17 62.1 0.0 1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCCH PF00642.24 KDO31629.1 - 7e-05 22.6 25.5 0.0073 16.2 6.1 4.3 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO31629.1 - 0.0097 16.6 10.2 0.071 13.8 0.4 3.0 2 1 1 3 3 3 2 Torus domain zf_CCCH_5 PF18384.1 KDO31629.1 - 0.01 16.0 6.2 4.5 7.5 0.3 3.4 3 0 0 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) CUE PF02845.16 KDO31629.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain Antifungal_prot PF11402.8 KDO31629.1 - 6.1 7.2 8.7 10 6.4 0.3 3.2 3 0 0 3 3 3 0 Antifungal protein CTD_bind PF04818.13 KDO31630.1 - 0.069 14.0 0.9 0.34 11.8 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase II-binding domain. zf-RING_2 PF13639.6 KDO31631.1 - 4.7e-14 52.5 6.1 4.7e-14 52.5 6.1 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO31631.1 - 1e-09 37.9 1.9 1e-09 37.9 1.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO31631.1 - 1.8e-09 37.2 6.0 4.5e-09 36.0 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO31631.1 - 2.6e-09 37.2 5.1 6.6e-09 35.9 5.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO31631.1 - 5.7e-09 35.8 4.4 5.7e-09 35.8 4.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO31631.1 - 9.2e-09 35.0 4.1 9.2e-09 35.0 4.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO31631.1 - 1.4e-07 31.3 4.7 3.1e-07 30.1 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO31631.1 - 2.1e-07 30.8 2.1 2.7e-07 30.5 0.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO31631.1 - 1.1e-05 25.4 2.3 2.2e-05 24.4 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO31631.1 - 0.00016 21.4 6.1 0.00038 20.3 6.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO31631.1 - 0.0014 18.2 6.7 0.0014 18.2 6.7 2.0 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KDO31631.1 - 0.018 15.2 2.5 0.046 13.8 2.5 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KDO31631.1 - 0.037 14.2 6.4 0.82 9.9 6.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 KDO31631.1 - 0.11 12.3 2.4 0.38 10.6 2.3 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PX PF00787.24 KDO31631.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 PX domain Prok-RING_1 PF14446.6 KDO31631.1 - 0.16 11.9 5.1 1.1 9.2 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KDO31631.1 - 0.21 11.4 3.1 0.54 10.1 3.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KDO31631.1 - 0.78 9.9 7.0 4.8 7.4 6.9 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KDO31631.1 - 4 7.6 9.3 8.5 6.5 8.3 2.2 1 1 1 2 2 2 0 Zinc-finger WD40 PF00400.32 KDO31632.1 - 2.2e-45 151.7 11.6 1.4e-06 28.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31632.1 - 2.6e-13 50.1 0.1 0.00018 21.7 0.1 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO31632.1 - 0.0011 18.0 0.6 0.14 11.1 0.0 3.3 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KDO31632.1 - 0.0025 17.7 0.1 1.3 8.8 0.1 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Me-amine-dh_H PF06433.11 KDO31632.1 - 0.084 11.7 0.0 0.47 9.3 0.0 1.9 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 KDO31632.1 - 0.11 12.5 0.2 2.9 8.0 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat UQ_con PF00179.26 KDO31633.1 - 2.4e-21 75.9 0.0 3.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EF-hand_1 PF00036.32 KDO31633.1 - 1.2e-12 46.4 1.3 2.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO31633.1 - 1e-10 41.9 0.1 1.7e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO31633.1 - 9.9e-10 37.5 1.1 5.9e-05 22.4 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO31633.1 - 3.7e-09 35.8 0.3 0.00052 19.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO31633.1 - 1.3e-07 31.4 4.0 5e-06 26.3 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO31633.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO31633.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region FYVE PF01363.21 KDO31634.1 - 2.8e-20 72.2 10.3 4.8e-20 71.5 10.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger C2 PF00168.30 KDO31634.1 - 1.2e-16 60.9 0.0 2.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain FYVE_2 PF02318.16 KDO31634.1 - 4.4e-05 23.7 4.7 4.4e-05 23.7 4.7 1.6 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.11 KDO31634.1 - 0.00018 20.6 7.0 0.00026 20.1 7.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KDO31634.1 - 0.0017 17.8 3.3 0.042 13.3 0.5 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF639) PRT_C PF08372.10 KDO31634.1 - 0.01 15.6 5.3 0.32 10.7 0.4 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal zf-RING_UBOX PF13445.6 KDO31634.1 - 0.82 9.7 6.6 2 8.5 6.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO31634.1 - 0.87 9.5 9.7 0.33 10.9 6.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_S27e PF01667.17 KDO31634.1 - 1.7 8.4 7.7 3.6 7.4 7.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KDO31634.1 - 3.7 7.1 7.7 13 5.4 7.7 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Peptidase_C69 PF03577.15 KDO31635.1 - 1.4e-56 192.1 0.0 5.8e-56 190.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C69 Xpo1 PF08389.12 KDO31636.1 - 0.00018 21.6 0.0 0.0011 19.1 0.0 2.4 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 KDO31636.1 - 0.23 11.4 0.6 9 6.3 0.0 3.3 3 0 0 3 3 3 0 Importin-beta N-terminal domain DUF842 PF05811.13 KDO31637.1 - 2e-42 144.0 15.4 2.2e-42 143.8 15.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) APG17 PF04108.12 KDO31637.1 - 0.0052 16.0 0.7 0.068 12.3 0.3 2.0 1 1 1 2 2 2 1 Autophagy protein Apg17 DUF4635 PF15466.6 KDO31637.1 - 0.0081 15.7 0.4 0.015 14.8 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) AAA_32 PF13654.6 KDO31637.1 - 0.014 14.2 0.5 0.014 14.3 0.5 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KDO31637.1 - 0.019 14.6 1.7 0.02 14.5 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Col_cuticle_N PF01484.17 KDO31637.1 - 0.51 10.4 2.9 0.35 10.9 0.7 1.9 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DHHC PF01529.20 KDO31638.1 - 2.1e-20 73.2 6.9 2.1e-20 73.2 6.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1282 PF06930.12 KDO31638.1 - 0.17 11.6 7.0 0.28 11.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) G3P_acyltransf PF02660.15 KDO31638.1 - 3.2 7.8 10.1 0.46 10.5 4.3 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase CactinC_cactus PF09732.9 KDO31639.1 - 8.6e-58 193.7 7.5 1.3e-57 193.1 7.5 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KDO31639.1 - 1.4e-56 191.3 1.9 1.4e-56 191.3 1.9 2.1 3 0 0 3 3 3 1 Conserved mid region of cactin Peptidase_S64 PF08192.11 KDO31639.1 - 1.3 7.4 3.8 2.3 6.6 3.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 Pkinase PF00069.25 KDO31640.1 - 5.7e-08 32.5 0.0 7.4e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31640.1 - 0.0026 17.1 0.0 0.0032 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 KDO31641.1 - 7.3e-10 38.6 1.5 2.8e-09 36.7 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KDO31641.1 - 1.1e-07 31.5 1.9 2.4e-07 30.4 0.1 2.4 2 0 0 2 2 2 1 F-box domain TetR_C_31 PF17940.1 KDO31641.1 - 0.014 15.6 3.5 0.72 10.1 0.6 3.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CCDC92 PF14916.6 KDO31642.1 - 0.041 13.6 0.8 0.13 12.1 0.7 1.9 1 1 1 2 2 2 0 Coiled-coil domain of unknown function DUF349 PF03993.12 KDO31642.1 - 0.047 14.0 0.8 0.1 12.9 0.8 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) SlyX PF04102.12 KDO31642.1 - 0.055 14.1 0.9 0.055 14.1 0.9 2.3 1 1 1 2 2 2 0 SlyX HIP1_clath_bdg PF16515.5 KDO31642.1 - 0.058 14.0 5.7 0.089 13.4 5.7 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 KDO31642.1 - 0.075 11.7 0.4 0.076 11.7 0.4 1.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 KDO31642.1 - 0.082 12.9 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 KDO31642.1 - 0.53 8.1 2.2 0.69 7.8 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KDO31642.1 - 0.77 9.8 4.6 2.8 8.0 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KDO31642.1 - 0.93 10.0 3.7 2.2 8.8 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 PKD_channel PF08016.12 KDO31643.1 - 3.7e-13 49.0 2.8 3.7e-13 49.0 2.8 1.9 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KDO31643.1 - 0.025 13.8 15.4 0.08 12.2 15.1 1.9 1 1 1 2 2 2 0 Ion transport protein NCBP3 PF10309.9 KDO31644.1 - 4.4e-14 52.1 0.0 9.7e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KDO31644.1 - 0.00019 21.4 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain FAD_syn PF06574.12 KDO31644.1 - 0.015 15.2 0.1 0.097 12.6 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase WD-3 PF09765.9 KDO31645.1 - 5.8e-68 229.3 0.0 6.7e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 KDO31645.1 - 4.5e-27 94.0 3.1 9e-27 93.1 2.7 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KDO31645.1 - 1.8e-05 24.9 5.0 3.6e-05 24.0 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KDO31645.1 - 0.00042 20.3 0.5 0.001 19.1 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 KDO31645.1 - 0.0018 18.5 0.5 0.0035 17.6 0.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-rbx1 PF12678.7 KDO31645.1 - 0.0036 17.5 2.8 0.0075 16.5 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain PaaX_C PF08223.11 KDO31645.1 - 0.082 13.2 2.3 0.3 11.4 0.1 2.7 2 1 1 3 3 3 0 PaaX-like protein C-terminal domain zf-RING-like PF08746.11 KDO31645.1 - 0.084 13.2 0.7 0.24 11.7 0.7 1.8 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 KDO31645.1 - 0.088 12.9 1.9 0.24 11.5 1.9 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zf-HC5HC2H_2 PF13832.6 KDO31645.1 - 0.13 12.4 0.8 0.23 11.6 0.8 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.7 KDO31645.1 - 0.18 11.9 3.4 0.34 11.1 3.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 KDO31645.1 - 1.3 8.9 6.7 27 4.7 6.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MazG-like PF12643.7 KDO31646.1 - 9.6e-12 45.0 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 KDO31646.1 - 2.4e-06 27.6 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain GCS PF03074.16 KDO31647.1 - 2.3e-157 524.1 0.0 2.9e-157 523.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Aldedh PF00171.22 KDO31649.1 - 7.2e-156 519.3 0.2 8.8e-156 519.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 KDO31650.1 - 9.6e-73 244.8 0.0 1.5e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31650.1 - 2e-37 128.9 0.0 3.2e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO31650.1 - 1.2e-14 54.7 0.1 3.5e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 KDO31650.1 - 9.9e-09 35.5 0.0 0.00075 19.9 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO31650.1 - 5.2e-08 32.2 0.2 0.0019 18.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KDO31650.1 - 1.1e-07 30.9 0.3 0.00066 19.0 0.0 3.7 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 KDO31650.1 - 0.0019 17.6 0.3 0.015 14.6 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO31650.1 - 0.032 13.6 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Kinase-like EF-hand_5 PF13202.6 KDO31650.1 - 0.034 13.6 0.0 0.094 12.3 0.0 1.8 1 0 0 1 1 1 0 EF hand Pkinase_fungal PF17667.1 KDO31650.1 - 0.082 11.7 0.2 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Pollen_Ole_e_I PF01190.17 KDO31650.1 - 0.12 12.8 0.3 0.33 11.3 0.1 1.8 2 0 0 2 2 2 0 Pollen proteins Ole e I like FTA2 PF13095.6 KDO31650.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PH_11 PF15413.6 KDO31650.1 - 0.23 11.9 0.8 1.5 9.3 0.8 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain WW PF00397.26 KDO31651.1 - 1.2e-16 60.4 9.4 9.1e-07 28.9 0.7 3.5 3 0 0 3 3 3 3 WW domain IQ PF00612.27 KDO31651.1 - 1.8e-12 45.8 84.7 0.018 14.8 0.2 13.1 13 0 0 13 13 13 10 IQ calmodulin-binding motif zf-B_box PF00643.24 KDO31651.1 - 0.012 15.7 55.5 0.82 9.9 5.9 4.6 4 0 0 4 4 4 0 B-box zinc finger SNase PF00565.17 KDO31653.1 - 6.5e-23 81.3 0.0 8.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Spc7 PF08317.11 KDO31654.1 - 0.0036 16.2 22.1 0.056 12.3 13.7 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF3584 PF12128.8 KDO31654.1 - 0.038 11.5 17.7 0.051 11.1 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 KDO31654.1 - 0.045 12.3 15.7 0.072 11.6 15.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Filament PF00038.21 KDO31654.1 - 0.081 12.5 19.9 0.94 9.0 11.9 2.6 1 1 1 2 2 2 0 Intermediate filament protein Fez1 PF06818.15 KDO31654.1 - 0.3 11.5 22.1 0.072 13.5 18.5 1.8 2 0 0 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 KDO31654.1 - 0.44 10.6 24.6 0.047 13.7 19.9 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KDO31654.1 - 0.51 9.4 15.4 0.86 8.6 15.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 KDO31654.1 - 0.91 9.0 27.4 0.93 9.0 25.8 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 KDO31654.1 - 2 6.9 9.3 2.8 6.5 9.3 1.1 1 0 0 1 1 1 0 AAA domain CC2-LZ PF16516.5 KDO31654.1 - 2.7 8.4 17.4 10 6.5 3.2 3.1 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FapA PF03961.13 KDO31654.1 - 3.4 6.2 8.8 8.3 4.9 8.5 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 KDO31654.1 - 4.9 7.4 10.8 0.76 10.0 0.8 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KDO31654.1 - 5.6 6.2 15.1 11 5.3 15.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Noelin-1 PF12308.8 KDO31654.1 - 5.8 7.0 11.7 0.069 13.1 2.2 2.5 2 2 1 3 3 3 0 Neurogenesis glycoprotein TBCA PF02970.16 KDO31654.1 - 7.4 7.0 11.1 2.1 8.7 4.6 2.8 2 0 0 2 2 2 0 Tubulin binding cofactor A PGM_PMM_I PF02878.16 KDO31655.1 - 1.7e-17 63.4 0.0 5.1e-08 32.7 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KDO31655.1 - 5.6e-10 39.2 0.5 2.4e-09 37.2 0.2 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ank_2 PF12796.7 KDO31656.1 - 3.4e-33 114.1 7.4 4.2e-08 33.7 0.1 7.4 3 3 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO31656.1 - 2.7e-20 72.2 17.9 4.5e-05 23.6 0.0 9.0 8 3 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31656.1 - 3.8e-20 69.8 16.5 0.31 11.7 0.0 13.2 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 KDO31656.1 - 5.8e-19 67.6 19.9 0.48 11.0 0.0 11.7 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.6 KDO31656.1 - 2.7e-12 47.0 12.3 0.024 15.2 0.0 8.8 5 4 5 10 10 10 4 Ankyrin repeats (many copies) DUF4536 PF15055.6 KDO31657.1 - 0.016 15.4 0.2 0.023 15.0 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) Dimer_Tnp_hAT PF05699.14 KDO31658.1 - 0.00036 20.2 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-H2C2_5 PF13909.6 KDO31658.1 - 3.4 7.5 15.2 3 7.7 3.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Complex1_LYR PF05347.15 KDO31659.1 - 0.00016 21.7 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO31659.1 - 0.0049 17.6 0.3 0.01 16.5 0.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Gemini_V2 PF01524.17 KDO31659.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Geminivirus V2 protein HLH PF00010.26 KDO31660.1 - 9.2e-10 38.3 0.4 1.7e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Torus PF16131.5 KDO31661.1 - 0.016 15.9 0.1 0.03 15.0 0.1 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH PF00642.24 KDO31661.1 - 0.019 14.9 4.5 0.038 13.9 4.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_23 PF13489.6 KDO31661.1 - 0.041 13.7 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RelB_transactiv PF16181.5 KDO31661.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 RelB transactivation domain zf-CCCH_4 PF18044.1 KDO31661.1 - 0.45 10.4 5.2 1 9.3 5.2 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger Abhydrolase_1 PF00561.20 KDO31662.1 - 2.4e-33 115.9 0.0 3.2e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO31662.1 - 5.8e-12 45.4 0.0 3.8e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO31662.1 - 4.4e-08 34.0 0.2 7.9e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KDO31662.1 - 0.00015 21.8 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.12 KDO31662.1 - 0.029 13.2 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 EGF_2 PF07974.13 KDO31663.1 - 0.00015 22.1 10.1 0.00015 22.1 10.1 5.7 4 1 1 5 5 5 2 EGF-like domain EGF_Tenascin PF18720.1 KDO31663.1 - 0.0039 17.2 8.1 0.0039 17.2 8.1 4.2 3 1 0 3 3 3 1 Tenascin EGF domain EGF PF00008.27 KDO31663.1 - 0.016 15.5 2.7 0.016 15.5 2.7 4.8 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 KDO31663.1 - 9.9 6.4 46.0 1.5 9.0 17.3 4.7 2 2 2 4 4 4 0 Laminin EGF domain DUF2423 PF10338.9 KDO31664.1 - 1.3e-05 25.3 0.6 1.3e-05 25.3 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF349 PF03993.12 KDO31664.1 - 2.1 8.7 10.5 4.7 7.6 0.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) MgsA_C PF12002.8 KDO31665.1 - 2.6e-49 167.4 0.0 6.6e-49 166.1 0.0 1.7 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KDO31665.1 - 1.7e-26 92.4 0.1 3.6e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KDO31665.1 - 4.1e-15 56.4 0.0 8.1e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KDO31665.1 - 4.5e-10 39.5 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO31665.1 - 4e-08 33.4 0.0 2e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO31665.1 - 7.8e-07 29.6 0.1 0.00058 20.3 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 KDO31665.1 - 6.8e-06 25.6 0.0 0.003 17.0 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KDO31665.1 - 0.00011 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KDO31665.1 - 0.00025 20.8 0.0 0.013 15.2 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 KDO31665.1 - 0.00033 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KDO31665.1 - 0.0018 17.5 0.0 0.0067 15.7 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KDO31665.1 - 0.0021 18.3 0.1 0.19 12.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO31665.1 - 0.0036 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KDO31665.1 - 0.0047 16.8 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KDO31665.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNF220 PF15926.5 KDO31665.1 - 0.012 15.3 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 AAA_19 PF13245.6 KDO31665.1 - 0.014 15.8 0.1 1.1 9.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KDO31665.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KDO31665.1 - 0.019 15.0 0.0 3.2 7.7 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 KDO31665.1 - 0.046 13.1 0.0 0.46 9.9 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 KDO31665.1 - 0.06 12.5 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KDO31665.1 - 0.064 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KDO31665.1 - 0.084 12.8 0.0 0.63 9.9 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KDO31665.1 - 0.097 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 KDO31665.1 - 0.097 12.2 0.2 0.34 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO31665.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KDO31665.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ank_2 PF12796.7 KDO31666.1 - 8.8e-06 26.2 0.4 0.00014 22.4 0.3 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31666.1 - 1.5e-05 25.4 6.0 0.00024 21.6 0.5 3.8 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31666.1 - 1.8e-05 24.7 6.7 0.0014 19.0 0.1 4.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KDO31666.1 - 0.00019 21.7 3.5 0.00025 21.3 1.3 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO31666.1 - 0.00024 21.4 4.6 0.00053 20.3 0.1 3.5 3 1 0 3 3 3 1 Ankyrin repeat TetR_C_15 PF17918.1 KDO31666.1 - 0.078 13.7 0.5 0.078 13.7 0.5 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NTP_transf_3 PF12804.7 KDO31667.1 - 0.0046 17.3 0.4 0.025 14.9 0.1 2.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain Porin_OmpG PF09381.10 KDO31668.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) PARP PF00644.20 KDO31669.1 - 3.2e-56 190.0 0.0 5.3e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KDO31669.1 - 2.8e-42 144.0 0.3 4.6e-42 143.3 0.3 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KDO31669.1 - 8.3e-13 48.2 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 WGR domain Baculo_PP31 PF05311.11 KDO31669.1 - 0.047 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CCDC53 PF10152.9 KDO31670.1 - 1.7e-23 83.7 0.0 8.2e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex CCDC53 PF10152.9 KDO31671.1 - 5.6e-13 49.6 0.4 8.1e-13 49.1 0.4 1.4 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex cNMP_binding PF00027.29 KDO31672.1 - 2.8e-19 69.0 0.0 5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO31672.1 - 1.6e-14 53.7 7.3 2.4e-14 53.2 7.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO31672.1 - 0.82 9.7 7.8 0.037 14.0 1.7 2.1 2 0 0 2 2 2 0 Ion channel Titin_Ig-rpts PF06582.12 KDO31673.1 - 0.31 11.0 3.4 7.7 6.6 0.0 3.0 3 0 0 3 3 3 0 Titin repeat LRR_8 PF13855.6 KDO31674.1 - 2.5e-20 72.0 12.7 1e-09 38.0 1.1 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO31674.1 - 9.4e-16 57.7 3.7 2.2e-05 24.7 0.0 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO31674.1 - 2.2e-09 36.6 7.5 0.22 11.7 0.1 5.4 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KDO31674.1 - 1.3e-06 28.1 5.7 3.5 8.5 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat HTH_8 PF02954.19 KDO31674.1 - 0.068 13.0 0.5 0.16 11.7 0.5 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family LRR_9 PF14580.6 KDO31674.1 - 0.084 12.4 0.2 0.15 11.5 0.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeat TRP PF06011.12 KDO31677.1 - 8.1e-08 31.4 33.5 1.1e-06 27.7 33.5 2.4 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF4181 PF13789.6 KDO31677.1 - 0.051 13.9 0.1 0.051 13.9 0.1 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4181) OppC_N PF12911.7 KDO31677.1 - 2.4 8.2 0.0 2.4 8.2 0.0 4.6 5 1 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C Kelch_1 PF01344.25 KDO31678.1 - 1.3e-26 91.9 0.1 4e-09 35.9 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KDO31678.1 - 1.6e-25 88.8 0.5 4.4e-07 29.8 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KDO31678.1 - 6.7e-25 86.8 2.1 1.1e-08 35.1 0.2 5.8 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KDO31678.1 - 3.9e-24 83.7 1.3 1.8e-07 30.9 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KDO31678.1 - 8e-23 79.9 1.4 1.6e-06 28.2 0.1 4.4 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 KDO31678.1 - 1.8e-22 79.7 0.0 3.4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KDO31678.1 - 5.2e-20 71.0 0.2 7.8e-08 32.1 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Myotub-related PF06602.14 KDO31679.1 - 5.7e-122 407.0 0.0 7.5e-122 406.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KDO31679.1 - 0.0019 18.2 0.1 0.0036 17.3 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family zf-RanBP PF00641.18 KDO31679.1 - 0.0046 16.3 2.4 0.0046 16.3 2.4 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Y_phosphatase PF00102.27 KDO31679.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KDO31679.1 - 0.0087 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Lipase_3 PF01764.25 KDO31680.1 - 1.1e-14 54.5 0.0 3.8e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KDO31680.1 - 0.1 13.2 2.5 0.23 12.0 1.3 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO31680.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Phasin_2 PF09361.10 KDO31680.1 - 0.17 12.2 0.3 0.36 11.1 0.3 1.5 1 0 0 1 1 1 0 Phasin protein PP2C PF00481.21 KDO31681.1 - 3.1e-46 158.1 0.0 3.4e-45 154.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO31681.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C EF-hand_7 PF13499.6 KDO31684.1 - 2.2e-15 56.9 5.3 2e-07 31.4 1.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO31684.1 - 1.3e-14 52.5 0.8 5.8e-06 25.5 0.4 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KDO31684.1 - 1.4e-14 53.6 2.2 0.012 15.4 0.0 4.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KDO31684.1 - 6.1e-13 47.6 9.6 0.00017 21.3 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KDO31684.1 - 1.3e-10 40.3 3.5 5.2e-06 25.7 0.2 3.4 3 0 0 3 3 3 2 EF hand Glyco_trans_1_2 PF13524.6 KDO31684.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.7 3 0 0 3 3 3 0 Glycosyl transferases group 1 Peptidase_M22 PF00814.25 KDO31685.1 - 1.5e-75 254.4 0.1 1.8e-75 254.1 0.1 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KDO31685.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus FGGY_C PF02782.16 KDO31685.1 - 0.03 14.1 0.1 0.07 12.8 0.2 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain WW PF00397.26 KDO31687.1 - 5.3e-15 55.2 21.9 2.5e-08 33.8 5.9 3.1 3 0 0 3 3 3 2 WW domain IQ PF00612.27 KDO31687.1 - 1.9e-06 27.2 151.8 0.0074 16.0 0.8 21.9 23 0 0 23 23 23 12 IQ calmodulin-binding motif GIY-YIG PF01541.24 KDO31687.1 - 0.016 15.5 0.0 0.22 11.8 0.0 2.9 2 0 0 2 2 2 0 GIY-YIG catalytic domain zf-B_box PF00643.24 KDO31687.1 - 9.8 6.4 10.4 1.6 8.9 5.9 2.1 2 0 0 2 2 2 0 B-box zinc finger DZR PF12773.7 KDO31688.1 - 2.4e-21 75.5 30.5 1.3e-10 41.1 14.0 3.3 2 1 1 3 3 3 3 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO31688.1 - 4.7e-14 51.6 55.3 5.4e-05 22.8 10.3 4.3 4 0 0 4 4 4 4 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KDO31688.1 - 6.3e-13 49.3 17.9 0.0018 19.0 1.3 4.5 4 0 0 4 4 4 4 zinc-ribbon family NOB1_Zn_bind PF08772.11 KDO31688.1 - 9.3e-07 28.9 26.7 0.12 12.5 1.9 4.6 4 0 0 4 4 4 4 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 KDO31688.1 - 5.4e-06 25.6 44.6 0.017 14.5 2.7 4.4 4 0 0 4 4 4 4 zinc-ribbon domain Nudix_N_2 PF14803.6 KDO31688.1 - 0.0006 19.7 32.0 0.15 12.0 0.1 7.0 7 0 0 7 7 7 4 Nudix N-terminal zf-NADH-PPase PF09297.11 KDO31688.1 - 0.093 12.4 32.9 0.071 12.8 1.0 6.7 5 1 0 6 6 6 0 NADH pyrophosphatase zinc ribbon domain Yippee-Mis18 PF03226.14 KDO31688.1 - 0.94 9.7 5.7 0.43 10.8 0.7 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cys_rich_CPXG PF14255.6 KDO31688.1 - 4.5 7.3 0.0 4.5 7.3 0.0 3.9 5 0 0 5 5 5 0 Cysteine-rich CPXCG zf-UDP PF14569.6 KDO31688.1 - 8.5 6.6 14.9 2.5 8.3 0.7 3.5 3 0 0 3 3 3 0 Zinc-binding RING-finger Med26 PF08711.11 KDO31689.1 - 1.7e-05 24.8 0.0 3.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 KDO31690.1 - 8.1e-69 231.9 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31690.1 - 1.6e-39 135.7 0.0 2.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KDO31690.1 - 3.2e-11 43.4 0.1 6.9e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain FYVE PF01363.21 KDO31690.1 - 5.3e-06 26.5 15.9 1.2e-05 25.3 15.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger Kdo PF06293.14 KDO31690.1 - 0.0047 16.3 0.1 0.0091 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO31690.1 - 0.018 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KDO31690.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FYVE_2 PF02318.16 KDO31690.1 - 0.92 9.7 10.7 1.9 8.7 10.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DUF913 PF06025.12 KDO31691.1 - 1.1e-41 143.1 12.2 4.2e-38 131.3 0.1 5.0 2 1 2 4 4 4 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KDO31691.1 - 3.7e-30 105.6 4.0 6.3e-22 78.5 0.2 3.5 2 1 1 3 3 3 2 Domain of Unknown Function (DUF908) UBM PF14377.6 KDO31691.1 - 2.2e-19 68.2 19.7 8.6e-07 28.2 0.1 5.4 4 1 1 5 5 5 4 Ubiquitin binding region UBA PF00627.31 KDO31691.1 - 0.00026 20.8 0.1 0.00068 19.5 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF1824 PF08854.10 KDO31691.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) RRN3 PF05327.11 KDO31691.1 - 0.039 12.5 15.2 0.1 11.1 15.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KDO31691.1 - 0.48 8.7 14.7 0.77 8.0 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KDO31691.1 - 1.1 7.4 26.4 1.9 6.6 26.4 1.4 1 0 0 1 1 1 0 Nop14-like family D123 PF07065.14 KDO31692.1 - 1.2e-64 218.4 15.2 5.1e-62 209.8 2.6 4.0 2 1 1 3 3 3 2 D123 NOA36 PF06524.12 KDO31692.1 - 0.65 9.3 12.3 0.93 8.8 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KDO31692.1 - 1.2 9.2 4.5 1.7 8.7 4.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KDO31692.1 - 3.7 5.5 9.8 4.4 5.3 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 KDO31692.1 - 7.2 6.9 11.0 16 5.8 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) UCH PF00443.29 KDO31693.1 - 3.5e-70 236.4 0.0 5.1e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 KDO31693.1 - 1.8e-17 63.3 0.3 4e-17 62.2 0.3 1.5 1 0 0 1 1 1 1 PX domain UCH_1 PF13423.6 KDO31693.1 - 1.4e-15 57.7 0.0 5.4e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KDO31693.1 - 4.5e-11 43.2 0.0 1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Agenet PF05641.12 KDO31693.1 - 0.0029 18.0 0.0 0.0074 16.7 0.0 1.8 1 0 0 1 1 1 1 Agenet domain Med27 PF11571.8 KDO31693.1 - 0.16 12.3 0.1 0.47 10.8 0.1 1.7 1 0 0 1 1 1 0 Mediator complex subunit 27 PX PF00787.24 KDO31694.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 PX domain Adap_comp_sub PF00928.21 KDO31695.1 - 1.9e-91 306.1 0.1 2.4e-91 305.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KDO31695.1 - 2.4e-07 30.8 1.5 4.4e-07 29.9 1.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 KDO31695.1 - 0.022 14.8 0.1 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 Regulated-SNARE-like domain Myb_DNA-binding PF00249.31 KDO31696.1 - 5.4e-09 36.1 0.0 0.022 14.9 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO31696.1 - 0.002 18.3 0.0 1 9.7 0.0 3.5 2 1 1 3 3 3 1 Myb-like DNA-binding domain Imm8 PF15586.6 KDO31696.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 8 NapB PF03892.14 KDO31696.1 - 1.2 9.2 5.9 12 5.9 1.0 3.0 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) BUD22 PF09073.10 KDO31696.1 - 1.3 8.3 15.6 0.15 11.4 4.8 2.2 2 0 0 2 2 2 0 BUD22 DUF2024 PF09630.10 KDO31696.1 - 1.5 8.7 3.7 12 5.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Haem_bd PF14376.6 KDO31696.1 - 2.3 8.2 5.8 2.2 8.2 0.8 2.5 2 0 0 2 2 2 0 Haem-binding domain Cytochrome_C7 PF14522.6 KDO31696.1 - 2.3 8.3 10.6 4 7.5 8.5 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_NNT PF03264.14 KDO31696.1 - 4 7.1 7.9 11 5.6 0.2 2.6 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region DUF3408 PF11888.8 KDO31696.1 - 7.8 6.6 8.1 1.6 8.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Retrotran_gag_2 PF14223.6 KDO31697.1 - 4.5e-05 23.1 0.0 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zinc-ribbons_6 PF07191.12 KDO31697.1 - 5.5 7.0 14.3 1 9.4 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbons Myb_DNA-binding PF00249.31 KDO31698.1 - 0.00056 20.0 0.1 0.054 13.7 0.2 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Retrotran_gag_2 PF14223.6 KDO31698.1 - 0.0056 16.4 0.0 1 9.1 0.0 2.7 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type TMCCDC2 PF15844.5 KDO31698.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 NOA36 PF06524.12 KDO31698.1 - 1.6 8.0 9.0 2.9 7.1 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein zf-RING_2 PF13639.6 KDO31700.1 - 7.7e-10 38.9 3.2 1.1e-09 38.5 3.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO31700.1 - 9e-09 35.5 2.1 1.4e-08 34.8 2.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO31700.1 - 2.1e-08 33.9 2.2 3e-08 33.4 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO31700.1 - 8e-07 28.8 3.3 1.3e-06 28.2 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO31700.1 - 1.5e-06 27.8 5.7 2.5e-06 27.1 5.7 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO31700.1 - 3.9e-06 26.8 1.9 5.9e-06 26.2 1.9 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO31700.1 - 2.1e-05 24.5 0.8 3.6e-05 23.7 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO31700.1 - 0.0001 21.8 2.7 0.00017 21.2 2.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KDO31700.1 - 0.00011 22.2 2.0 0.00023 21.2 2.0 1.5 1 1 0 1 1 1 1 RING-variant domain zf-RING_5 PF14634.6 KDO31700.1 - 0.00044 20.1 1.8 0.00064 19.6 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO31700.1 - 0.001 18.9 2.2 0.0014 18.4 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KDO31700.1 - 0.0049 16.6 0.4 0.0078 16.0 0.4 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KDO31700.1 - 0.012 15.7 3.4 0.039 14.1 3.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KDO31700.1 - 0.053 13.6 0.7 0.089 12.9 0.7 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_4 PF14447.6 KDO31700.1 - 0.38 10.6 3.2 0.6 10.0 3.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L39 PF00832.20 KDO31701.1 - 3.1e-22 77.9 9.0 4.5e-22 77.4 9.0 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein EGF_2 PF07974.13 KDO31701.1 - 6.5e-06 26.4 25.7 1.1e-05 25.6 11.7 5.3 4 1 1 5 5 5 2 EGF-like domain EGF PF00008.27 KDO31701.1 - 0.014 15.7 21.2 0.023 15.0 6.1 5.0 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 KDO31701.1 - 6.3 7.0 54.6 0.29 11.3 16.9 4.5 3 2 2 5 5 5 0 Laminin EGF domain Abhydrolase_6 PF12697.7 KDO31702.1 - 1.5e-11 45.3 5.2 2e-11 44.9 5.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO31702.1 - 1.4e-08 34.7 1.2 1.7e-08 34.4 0.2 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO31702.1 - 2.3e-08 33.6 0.0 3.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KDO31702.1 - 0.013 15.7 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KDO31702.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acyl_transf_1 PF00698.21 KDO31702.1 - 0.026 14.0 0.1 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 Acyl transferase domain Abhydro_lipase PF04083.16 KDO31702.1 - 0.087 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.13 KDO31702.1 - 0.11 11.0 0.0 0.22 10.0 0.0 1.4 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PH PF00169.29 KDO31703.1 - 4.3e-06 27.2 0.0 8.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Fascin PF06268.13 KDO31703.1 - 0.0045 17.2 0.2 0.0084 16.3 0.1 1.5 1 1 0 1 1 1 1 Fascin domain Ribosomal_S24e PF01282.19 KDO31704.1 - 1.9e-34 117.4 0.8 3e-34 116.8 0.0 1.7 2 1 0 2 2 2 1 Ribosomal protein S24e Lung_7-TM_R PF06814.13 KDO31706.1 - 6.1e-45 153.7 10.6 8.5e-45 153.2 10.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor 7tm_7 PF08395.12 KDO31706.1 - 2 7.6 18.2 1.6 7.8 5.4 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor SNARE PF05739.19 KDO31707.1 - 6.1e-05 22.9 0.9 0.00036 20.5 0.7 2.0 2 0 0 2 2 2 1 SNARE domain Tropomyosin PF00261.20 KDO31707.1 - 0.001 18.5 1.0 0.0013 18.1 1.0 1.1 1 0 0 1 1 1 1 Tropomyosin EzrA PF06160.12 KDO31707.1 - 0.0036 15.6 1.3 0.0051 15.1 1.3 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF5089 PF17002.5 KDO31707.1 - 0.021 14.7 4.1 0.025 14.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) MCU PF04678.13 KDO31707.1 - 0.033 14.3 0.3 0.038 14.1 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RasGAP_C PF03836.15 KDO31707.1 - 0.035 14.2 1.9 0.045 13.9 1.9 1.1 1 0 0 1 1 1 0 RasGAP C-terminus Sec20 PF03908.13 KDO31707.1 - 0.043 13.7 2.7 0.058 13.3 1.4 1.8 1 1 1 2 2 2 0 Sec20 DUF3606 PF12244.8 KDO31707.1 - 0.063 13.2 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) DUF3450 PF11932.8 KDO31707.1 - 0.075 12.3 4.2 0.089 12.1 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.6 KDO31707.1 - 0.1 13.0 2.9 1.1 9.6 1.2 2.0 1 1 1 2 2 2 0 Syntaxin-like protein MSA-2c PF12238.8 KDO31707.1 - 0.11 12.5 0.5 0.13 12.3 0.5 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c SlyX PF04102.12 KDO31707.1 - 1.7 9.3 7.5 7.8 7.2 1.1 2.1 1 1 1 2 2 2 0 SlyX ORC5_C PF14630.6 KDO31708.1 - 4.6e-23 82.1 0.9 5.3e-23 82.0 0.3 1.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KDO31708.1 - 1.6e-10 41.7 0.0 3.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO31708.1 - 1.2e-08 35.3 0.0 2.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cas_St_Csn2 PF16813.5 KDO31708.1 - 0.028 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St Macro PF01661.21 KDO31709.1 - 1e-34 119.1 0.0 1.6e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Macro domain Casc1_N PF15927.5 KDO31710.1 - 4.7e-36 124.4 14.0 4.7e-36 124.4 14.0 2.1 1 1 1 2 2 2 1 Cancer susceptibility candidate 1 N-terminus COG2 PF06148.11 KDO31710.1 - 0.0097 16.0 0.2 1.4 9.0 0.4 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 SH3_19 PF18597.1 KDO31710.1 - 0.066 13.0 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain PAPS_reduct PF01507.19 KDO31711.1 - 3.8e-45 154.1 0.0 5e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.24 KDO31711.1 - 7.1e-13 48.6 0.8 6.6e-12 45.5 0.4 2.3 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 KDO31711.1 - 8.9e-05 22.8 0.2 0.00023 21.5 0.2 1.7 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KDO31711.1 - 0.0013 18.7 0.2 0.0025 17.8 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KDO31711.1 - 0.034 14.6 0.1 0.067 13.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 KDO31711.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-C2H2_10 PF16588.5 KDO31711.1 - 0.15 11.8 1.5 0.38 10.5 0.7 2.0 2 0 0 2 2 2 0 C2H2 zinc-finger PH PF00169.29 KDO31712.1 - 1.2e-09 38.6 0.1 9.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 KDO31712.1 - 1e-07 32.0 0.6 5.2e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 PH domain PH_11 PF15413.6 KDO31712.1 - 0.0055 17.1 0.2 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KDO31712.1 - 0.01 16.1 0.3 0.48 10.7 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain PDZ_6 PF17820.1 KDO31712.1 - 0.029 14.2 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 PDZ domain zf-HIT PF04438.16 KDO31713.1 - 3.8e-09 36.2 10.8 6.8e-09 35.4 10.8 1.4 1 0 0 1 1 1 1 HIT zinc finger SHQ1 PF04925.15 KDO31713.1 - 0.052 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein PolC_DP2 PF03833.13 KDO31713.1 - 0.062 11.2 0.6 0.077 10.9 0.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 KDO31713.1 - 0.13 12.6 5.7 0.11 12.9 3.3 2.1 2 0 0 2 2 2 0 C1 domain zf-MYND PF01753.18 KDO31713.1 - 0.15 12.2 11.7 0.31 11.2 11.7 1.5 1 0 0 1 1 1 0 MYND finger Exonuc_VII_S PF02609.16 KDO31713.1 - 0.17 12.0 0.4 0.42 10.7 0.4 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit DUF4404 PF14357.6 KDO31713.1 - 0.51 11.0 3.4 0.25 12.0 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) HA PF03457.14 KDO31714.1 - 7.2e-28 96.7 0.0 0.00046 20.5 0.0 6.2 6 0 0 6 6 6 6 Helicase associated domain Piezo_RRas_bdg PF12166.8 KDO31715.1 - 1.8e-77 261.5 0.0 2.8e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain fn3 PF00041.21 KDO31715.1 - 4.9e-14 52.5 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KDO31715.1 - 0.0078 16.8 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain XPG_N PF00752.17 KDO31717.1 - 1.4e-21 76.8 0.0 2.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KDO31717.1 - 4.1e-13 49.5 0.3 1.5e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 KDO31717.1 - 9.5e-08 31.8 0.3 1.8e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 XPG domain containing IQ PF00612.27 KDO31718.1 - 0.44 10.5 7.3 7.5 6.6 1.4 3.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif START PF01852.19 KDO31719.1 - 2.2e-13 50.1 0.3 5.7e-13 48.8 0.1 1.7 2 0 0 2 2 2 1 START domain PDZ_6 PF17820.1 KDO31719.1 - 4.5e-05 23.2 0.2 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Pkinase PF00069.25 KDO31720.1 - 2.4e-35 122.2 0.0 1.7e-25 89.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31720.1 - 1.4e-21 76.9 0.0 3.8e-18 65.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO31720.1 - 0.015 14.6 0.6 3.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KDO31720.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain ClpB_D2-small PF10431.9 KDO31723.1 - 5.3e-24 84.1 1.0 3e-23 81.7 0.3 2.2 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.14 KDO31723.1 - 3.7e-16 59.7 0.0 6.1e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) PPR_2 PF13041.6 KDO31724.1 - 2.2e-14 53.4 0.1 0.00089 19.4 0.0 5.7 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.20 KDO31724.1 - 6.5e-10 38.6 0.2 0.1 12.9 0.0 6.3 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KDO31724.1 - 5.3e-09 36.0 4.1 0.96 9.6 0.0 5.7 5 1 1 6 6 6 3 Pentatricopeptide repeat domain Smr PF01713.21 KDO31724.1 - 5.9e-07 29.7 0.0 2.5e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 Smr domain PPR_long PF17177.4 KDO31724.1 - 1.5e-06 27.8 0.0 0.0031 16.9 0.0 3.6 1 1 3 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KDO31724.1 - 0.0027 18.2 2.8 14 6.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31724.1 - 0.0032 18.2 9.4 5.6 8.1 0.0 6.5 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO31724.1 - 0.061 14.0 0.8 41 5.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO31724.1 - 0.079 12.3 4.9 5.3 6.3 0.0 3.1 3 1 0 3 3 3 0 MalT-like TPR region DNA_topoisoIV PF00521.20 KDO31725.1 - 1.9e-109 366.4 0.0 3.4e-109 365.6 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KDO31725.1 - 4.7e-39 133.6 0.1 4.7e-39 133.6 0.1 1.8 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KDO31725.1 - 1.2e-21 76.9 0.4 2.4e-21 76.0 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KDO31725.1 - 4.9e-10 39.9 0.0 1.7e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KDO31725.1 - 0.0026 18.0 0.0 0.0082 16.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain PX PF00787.24 KDO31726.1 - 0.0026 17.7 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 PX domain DUF953 PF06110.11 KDO31727.1 - 1.4e-19 69.8 0.0 2.8e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 KDO31727.1 - 0.0084 16.0 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin PF00085.20 KDO31727.1 - 0.017 15.1 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 KDO31727.1 - 0.029 14.8 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain DUF953 PF06110.11 KDO31728.1 - 1.5e-23 82.7 0.0 3.4e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) DUF953 PF06110.11 KDO31729.1 - 2.8e-29 101.2 0.0 2.2e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Pkinase PF00069.25 KDO31730.1 - 2.9e-65 220.2 0.0 4.3e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31730.1 - 2.2e-29 102.5 0.1 1.7e-28 99.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO31730.1 - 6.6e-20 70.9 0.0 1.9e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) START PF01852.19 KDO31730.1 - 1.4e-08 34.4 0.0 9.6e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 START domain Kdo PF06293.14 KDO31730.1 - 4e-05 23.1 0.6 0.00085 18.7 0.1 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 KDO31730.1 - 0.003 18.2 1.1 0.01 16.5 1.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KDO31730.1 - 0.0046 16.3 0.2 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Vert_IL3-reg_TF PF06529.11 KDO31730.1 - 0.0071 15.5 2.0 0.012 14.8 2.0 1.2 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor Haspin_kinase PF12330.8 KDO31730.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KDO31730.1 - 0.076 12.6 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 RIO1 family YukC PF10140.9 KDO31730.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KDO31730.1 - 0.14 12.0 0.8 1.1 9.1 0.7 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO31731.1 - 1.2e-65 221.5 0.0 1.9e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31731.1 - 2.4e-29 102.4 0.2 3.1e-28 98.8 0.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 KDO31731.1 - 6.4e-18 64.6 0.0 2.9e-17 62.5 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) START PF01852.19 KDO31731.1 - 2e-09 37.2 0.0 2.2e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 START domain Pkinase_C PF00433.24 KDO31731.1 - 6.3e-06 26.8 7.3 1.4e-05 25.7 7.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 KDO31731.1 - 0.00014 21.2 0.4 0.0004 19.8 0.4 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO31731.1 - 0.0048 16.2 0.8 0.019 14.3 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KDO31731.1 - 0.013 14.4 0.8 0.027 13.4 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KDO31731.1 - 0.068 12.8 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 RIO1 family YukC PF10140.9 KDO31731.1 - 0.076 11.8 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KDO31731.1 - 0.16 11.8 0.7 1.1 9.1 0.6 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA_2 PF07724.14 KDO31732.1 - 1.2e-49 168.8 0.0 4.5e-48 163.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KDO31732.1 - 1.6e-34 118.0 6.8 5.6e-34 116.2 0.3 3.2 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 KDO31732.1 - 1.6e-25 90.1 0.0 9.4e-13 48.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KDO31732.1 - 3.8e-22 78.1 0.3 3.8e-22 78.1 0.3 2.9 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KDO31732.1 - 3.1e-18 66.1 0.5 3e-11 43.5 0.0 3.9 2 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KDO31732.1 - 2e-13 50.2 3.1 5.8e-09 36.0 0.6 3.2 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 KDO31732.1 - 4.4e-09 36.3 0.0 6.5e-07 29.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KDO31732.1 - 5e-09 36.6 8.4 0.0014 18.9 0.1 5.4 4 2 1 5 5 3 2 AAA domain AAA_16 PF13191.6 KDO31732.1 - 9.7e-09 35.8 23.6 5.5e-06 26.9 0.2 6.6 6 2 0 6 6 5 2 AAA ATPase domain IstB_IS21 PF01695.17 KDO31732.1 - 5.5e-08 32.7 0.0 0.0061 16.3 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KDO31732.1 - 2.6e-06 27.0 0.0 0.74 9.2 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KDO31732.1 - 8.4e-06 25.4 0.0 0.03 13.9 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KDO31732.1 - 1.7e-05 24.9 0.0 0.13 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KDO31732.1 - 2.7e-05 24.1 0.2 0.013 15.4 0.0 3.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KDO31732.1 - 2.7e-05 23.6 0.3 0.052 12.9 0.0 3.8 4 0 0 4 4 4 1 Bacterial TniB protein ATPase_2 PF01637.18 KDO31732.1 - 2.9e-05 24.1 0.0 4.5 7.1 0.0 3.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KDO31732.1 - 3.6e-05 24.3 0.0 0.16 12.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KDO31732.1 - 4.3e-05 23.3 1.9 0.62 9.8 0.0 4.7 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KDO31732.1 - 6.4e-05 22.6 4.3 0.0058 16.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain DNA_pol3_delta2 PF13177.6 KDO31732.1 - 0.00018 21.3 0.0 0.2 11.4 0.0 3.3 3 0 0 3 3 3 1 DNA polymerase III, delta subunit NACHT PF05729.12 KDO31732.1 - 0.00022 21.2 0.0 0.36 10.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 KDO31732.1 - 0.00029 21.0 0.0 0.84 9.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KDO31732.1 - 0.00043 20.6 0.1 0.64 10.4 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 KDO31732.1 - 0.002 18.3 2.5 0.84 9.8 0.0 4.2 4 1 0 4 4 4 1 AAA domain TIP49 PF06068.13 KDO31732.1 - 0.003 16.8 0.2 3.9 6.6 0.0 3.0 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_28 PF13521.6 KDO31732.1 - 0.003 17.8 6.2 5 7.4 0.0 4.3 4 2 0 4 4 3 0 AAA domain DUF815 PF05673.13 KDO31732.1 - 0.0034 16.6 0.0 4.7 6.3 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KDO31732.1 - 0.0035 17.3 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KDO31732.1 - 0.0038 17.0 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KDO31732.1 - 0.0039 17.2 0.1 0.44 10.5 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KDO31732.1 - 0.0046 16.9 0.4 4.8 7.1 0.0 3.2 4 0 0 4 4 3 0 RsgA GTPase ABC_tran PF00005.27 KDO31732.1 - 0.0053 17.3 0.4 0.93 10.0 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 KDO31732.1 - 0.011 16.2 10.9 0.19 12.2 0.0 3.5 2 1 0 2 2 1 0 AAA domain HA PF03457.14 KDO31732.1 - 0.012 15.9 0.0 0.058 13.7 0.0 2.2 1 0 0 1 1 1 0 Helicase associated domain AAA_29 PF13555.6 KDO31732.1 - 0.019 14.7 0.0 6.2 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 KDO31732.1 - 0.034 13.6 0.0 0.39 10.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KDO31732.1 - 0.034 13.8 2.7 1.8 8.3 0.0 4.0 3 2 0 3 3 3 0 AAA domain SRP54 PF00448.22 KDO31732.1 - 0.056 13.1 0.0 5.5 6.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 KDO31732.1 - 0.12 12.5 2.9 7 6.7 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_19 PF13245.6 KDO31732.1 - 0.12 12.8 1.9 1.9 8.8 0.1 3.2 2 2 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KDO31732.1 - 0.12 12.2 0.0 9 6.2 0.0 2.9 2 0 0 2 2 2 0 NTPase UvrD-helicase PF00580.21 KDO31732.1 - 0.14 11.6 2.6 0.27 10.7 1.6 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TcpS PF17456.2 KDO31732.1 - 0.96 9.5 2.6 2.4 8.2 1.2 2.2 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Flavodoxin_5 PF12724.7 KDO31733.1 - 0.0092 16.2 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_2 PF02525.17 KDO31733.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold FMN_red PF03358.15 KDO31733.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Aa_trans PF01490.18 KDO31736.1 - 2.8e-57 194.3 30.6 3.4e-57 194.0 30.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein B277 PF17623.2 KDO31736.1 - 0.028 13.5 1.4 0.032 13.3 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function TPR_MLP1_2 PF07926.12 KDO31739.1 - 0.0057 16.7 22.4 0.033 14.3 22.4 2.0 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 KDO31739.1 - 0.011 15.1 16.7 0.014 14.7 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF773 PF05600.12 KDO31739.1 - 0.016 14.0 0.7 0.016 14.0 0.7 2.1 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 CCDC144C PF14915.6 KDO31739.1 - 0.019 14.1 19.3 0.03 13.4 19.3 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region FliD_C PF07195.12 KDO31739.1 - 0.021 14.3 4.5 0.028 13.8 4.5 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus MIP-T3_C PF17749.1 KDO31739.1 - 0.022 14.7 8.4 0.033 14.2 8.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region V_ATPase_I PF01496.19 KDO31739.1 - 0.025 12.5 8.1 0.03 12.3 8.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 KDO31739.1 - 0.031 12.2 8.2 0.04 11.9 8.2 1.1 1 0 0 1 1 1 0 Prominin DivIC PF04977.15 KDO31739.1 - 0.033 13.9 4.0 0.033 13.9 4.0 3.6 1 1 3 4 4 4 0 Septum formation initiator RPW8 PF05659.11 KDO31739.1 - 0.054 13.2 4.8 0.041 13.6 2.2 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Vip3A_N PF12495.8 KDO31739.1 - 0.06 13.3 0.3 0.082 12.8 0.3 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal APG17 PF04108.12 KDO31739.1 - 0.072 12.2 13.1 0.016 14.4 6.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg17 CENP-F_leu_zip PF10473.9 KDO31739.1 - 0.11 12.5 23.2 0.098 12.7 20.8 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 KDO31739.1 - 0.11 12.5 13.4 0.057 13.4 8.3 2.0 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.6 KDO31739.1 - 0.13 10.9 11.5 0.16 10.6 11.5 1.0 1 0 0 1 1 1 0 AAA domain DUF737 PF05300.11 KDO31739.1 - 0.14 12.5 11.3 0.2 12.0 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Gp58 PF07902.11 KDO31739.1 - 0.19 10.0 6.9 0.23 9.7 6.9 1.0 1 0 0 1 1 1 0 gp58-like protein DUF4407 PF14362.6 KDO31739.1 - 0.2 11.0 11.6 0.26 10.6 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KDO31739.1 - 0.22 12.2 16.3 0.67 10.6 6.8 3.0 1 1 1 2 2 2 0 Initiation control protein YabA NUDE_C PF04880.13 KDO31739.1 - 0.25 11.8 0.3 0.25 11.8 0.3 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region ZapB PF06005.12 KDO31739.1 - 0.25 11.8 20.0 0.95 9.9 12.2 2.8 2 1 0 2 2 2 0 Cell division protein ZapB Fez1 PF06818.15 KDO31739.1 - 0.26 11.7 16.7 0.44 11.0 16.7 1.3 1 0 0 1 1 1 0 Fez1 Exonuc_VII_L PF02601.15 KDO31739.1 - 0.28 10.7 7.7 0.41 10.2 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 KDO31739.1 - 0.33 11.4 10.1 0.48 10.9 10.1 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB HMMR_N PF15905.5 KDO31739.1 - 0.44 10.0 22.2 0.24 10.8 14.2 1.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PEP-utilisers_N PF05524.13 KDO31739.1 - 0.47 10.6 14.0 0.086 13.0 6.8 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal GAS PF13851.6 KDO31739.1 - 0.53 9.6 20.5 1.1 8.6 20.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 KDO31739.1 - 0.56 9.4 7.9 0.73 9.0 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2064 PF09837.9 KDO31739.1 - 0.61 9.9 5.0 0.68 9.8 2.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) ADIP PF11559.8 KDO31739.1 - 0.63 10.1 22.7 0.19 11.8 12.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KDO31739.1 - 0.79 10.0 13.2 0.88 9.9 2.9 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) BSP_II PF05432.11 KDO31739.1 - 0.9 9.2 0.0 0.9 9.2 0.0 2.1 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) BST2 PF16716.5 KDO31739.1 - 0.98 10.0 17.9 0.84 10.3 12.5 2.9 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 KDO31739.1 - 1.1 9.3 12.7 2.4 8.2 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KDO31739.1 - 1.2 9.4 26.7 1.1 9.5 22.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 KDO31739.1 - 1.2 7.6 7.6 1.5 7.2 7.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.11 KDO31739.1 - 1.5 8.4 12.3 2 8.0 12.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4201 PF13870.6 KDO31739.1 - 2.2 8.0 18.3 1.6 8.4 7.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 KDO31739.1 - 2.2 8.9 10.9 4.5 7.9 10.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TBCA PF02970.16 KDO31739.1 - 2.3 8.6 17.2 0.36 11.2 7.6 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A Atg14 PF10186.9 KDO31739.1 - 2.8 7.0 10.8 3.7 6.6 10.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 KDO31739.1 - 2.8 8.4 20.3 0.36 11.2 11.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 KDO31739.1 - 2.9 8.2 19.7 0.4 11.0 8.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 KDO31739.1 - 3.1 7.7 16.9 0.43 10.5 8.3 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain KxDL PF10241.9 KDO31739.1 - 3.3 8.1 12.1 1.2 9.4 2.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Cortex-I_coil PF09304.10 KDO31739.1 - 3.3 8.0 15.9 0.59 10.4 4.6 2.3 1 1 0 2 2 2 0 Cortexillin I, coiled coil Fib_alpha PF08702.10 KDO31739.1 - 3.4 7.9 13.1 2.3 8.4 7.3 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KDO31739.1 - 3.6 7.9 6.7 2.2 8.6 3.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KDO31739.1 - 4.1 7.9 28.7 1.5 9.4 14.5 2.7 1 1 2 3 3 3 0 Apg6 coiled-coil region Nup54 PF13874.6 KDO31739.1 - 4.3 7.4 13.0 6 7.0 12.7 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 bZIP_1 PF00170.21 KDO31739.1 - 4.6 7.4 13.1 2.8 8.1 1.3 3.2 1 1 1 3 3 3 0 bZIP transcription factor Nsp1_C PF05064.13 KDO31739.1 - 4.9 7.0 14.6 5.1 6.9 12.2 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region BRE1 PF08647.11 KDO31739.1 - 5.9 7.0 18.3 2.2 8.4 13.6 2.6 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 KDO31739.1 - 6.2 6.6 12.8 4.2 7.1 9.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 KDO31739.1 - 8.9 6.4 18.5 0.95 9.5 7.0 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding NDUFA12 PF05071.16 KDO31740.1 - 8.7 7.3 8.0 1.2 10.1 0.1 2.8 3 1 0 3 3 3 0 NADH ubiquinone oxidoreductase subunit NDUFA12 FYVE PF01363.21 KDO31741.1 - 7.1e-10 38.9 3.3 1.3e-09 38.1 3.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Zf_RING PF16744.5 KDO31741.1 - 0.0091 16.1 1.1 0.0091 16.1 1.1 1.9 2 0 0 2 2 2 1 KIAA1045 RING finger SopE_GEF PF07487.13 KDO31741.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain zf-HIT PF04438.16 KDO31741.1 - 0.4 10.6 8.3 1.1 9.2 8.3 1.8 1 0 0 1 1 1 0 HIT zinc finger C1_2 PF03107.16 KDO31741.1 - 0.53 10.6 6.5 1.2 9.5 6.5 1.6 1 0 0 1 1 1 0 C1 domain DZR PF12773.7 KDO31741.1 - 6.4 6.9 10.1 14 5.8 8.0 2.4 2 1 0 2 2 2 0 Double zinc ribbon Siva PF05458.12 KDO31741.1 - 7.3 6.2 9.1 9.3 5.9 6.8 1.9 1 1 1 2 2 2 0 Cd27 binding protein (Siva) Mito_carr PF00153.27 KDO31742.1 - 4.3e-60 199.7 0.2 2.7e-19 68.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MMR_HSR1 PF01926.23 KDO31743.1 - 6.8e-18 64.8 0.1 1.9e-17 63.4 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase NOG1_N PF17835.1 KDO31743.1 - 1.5e-15 57.6 0.4 2.2e-15 57.0 0.4 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KDO31743.1 - 1.9e-14 53.2 0.0 5.6e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 KDO31743.1 - 4.5e-11 42.5 0.0 8.3e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KDO31743.1 - 0.00081 19.3 0.1 0.003 17.5 0.1 2.0 1 1 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 KDO31743.1 - 0.0066 16.2 0.0 0.009 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KDO31743.1 - 0.021 15.3 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KDO31743.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) gag-asp_proteas PF13975.6 KDO31743.1 - 0.12 12.9 0.0 4.1 8.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SepSecS PF05889.13 KDO31743.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Dynamin_N PF00350.23 KDO31743.1 - 0.17 11.9 0.6 2.4 8.2 0.2 2.4 2 1 0 3 3 3 0 Dynamin family Mito_carr PF00153.27 KDO31746.1 - 3.4e-52 174.3 2.6 1.5e-16 60.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ArsC PF03960.15 KDO31748.1 - 2.6e-09 37.0 0.0 2.7e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 ArsC family Thioredoxin_5 PF13743.6 KDO31748.1 - 0.12 12.0 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin SBF PF01758.16 KDO31749.1 - 4.7e-38 130.8 15.5 4.7e-38 130.8 15.5 2.3 3 0 0 3 3 3 1 Sodium Bile acid symporter family SBF_like PF13593.6 KDO31749.1 - 2e-09 37.2 26.6 2.6e-09 36.9 26.6 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Abhydrolase_6 PF12697.7 KDO31750.1 - 2e-08 35.1 3.0 2.5e-08 34.8 3.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO31750.1 - 4.9e-07 29.3 0.1 4.7e-06 26.1 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KDO31750.1 - 1e-05 25.1 0.1 3.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KDO31750.1 - 8.4e-05 22.3 0.1 0.00042 20.0 0.1 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KDO31750.1 - 0.0011 18.6 0.0 0.83 9.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KDO31750.1 - 0.0022 17.7 0.0 0.0078 15.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KDO31750.1 - 0.065 12.7 0.6 0.78 9.2 0.3 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase TPR_12 PF13424.6 KDO31751.1 - 6.9e-13 48.7 12.7 3.1e-08 33.8 1.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31751.1 - 1.3e-11 43.7 12.6 0.00085 19.3 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31751.1 - 1.9e-09 37.0 1.1 0.026 14.7 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO31751.1 - 6.1e-09 35.3 5.5 0.0008 19.3 0.1 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31751.1 - 2.1e-08 33.6 5.1 0.00099 18.8 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO31751.1 - 1e-06 28.4 14.4 0.0019 18.0 0.1 6.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31751.1 - 1.2e-06 28.8 22.9 0.34 11.8 0.4 6.9 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_21 PF09976.9 KDO31751.1 - 2e-06 27.6 5.5 0.0004 20.2 1.7 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KDO31751.1 - 2.1e-06 28.0 5.0 0.72 10.6 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO31751.1 - 2.5e-05 24.7 16.3 0.00061 20.3 2.5 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31751.1 - 2.7e-05 24.7 20.6 0.0043 17.7 4.1 5.8 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO31751.1 - 0.013 15.8 6.5 0.95 10.0 1.0 5.0 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO31751.1 - 0.015 15.8 9.1 1.8 9.4 2.1 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO31751.1 - 0.047 13.9 4.9 0.25 11.6 1.4 3.5 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KDO31751.1 - 0.072 13.2 0.6 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF357 PF04010.13 KDO31751.1 - 0.12 12.5 2.7 2.4 8.3 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF357) Paf67 PF10255.9 KDO31751.1 - 0.12 11.3 0.1 3.6 6.5 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_11 PF13414.6 KDO31751.1 - 0.15 11.8 2.9 13 5.5 0.1 4.1 4 1 0 4 4 4 0 TPR repeat DAO PF01266.24 KDO31752.1 - 3.5e-39 135.4 4.5 4e-39 135.2 4.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO31752.1 - 4.2e-06 26.1 0.5 6.2e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KDO31752.1 - 0.00015 22.2 0.0 0.00095 19.6 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KDO31752.1 - 0.0012 19.4 1.4 0.0058 17.2 1.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KDO31752.1 - 0.0032 16.8 2.4 0.013 14.8 1.9 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO31752.1 - 0.014 15.4 0.1 0.038 14.0 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KDO31752.1 - 0.02 14.2 0.6 0.061 12.6 0.4 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KDO31752.1 - 0.034 14.4 2.5 0.11 12.8 1.7 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KDO31752.1 - 0.045 13.3 0.2 0.27 10.8 0.3 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KDO31752.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KDO31752.1 - 0.17 12.1 0.4 0.59 10.4 0.3 1.8 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 KDO31752.1 - 0.54 9.3 1.2 0.77 8.8 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ank_2 PF12796.7 KDO31753.1 - 9e-22 77.5 5.5 2.1e-10 41.0 0.3 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31753.1 - 1.2e-19 70.4 13.6 3.9e-05 24.1 0.4 4.6 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31753.1 - 1.5e-15 57.0 14.8 0.00037 20.7 0.2 6.9 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31753.1 - 1.6e-11 43.4 11.0 0.84 10.4 0.0 7.2 4 1 3 7 7 7 4 Ankyrin repeat Ank PF00023.30 KDO31753.1 - 4.6e-05 23.7 7.1 8.2 7.1 0.6 6.2 2 2 3 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 KDO31753.1 - 0.0025 17.7 3.4 5.2 7.0 0.0 4.8 2 2 3 5 5 5 1 Domain of unknown function (DUF5049) YmaF PF12788.7 KDO31753.1 - 0.064 13.8 17.2 0.26 11.8 3.8 3.0 2 2 0 2 2 2 0 YmaF family DUF1707 PF08044.11 KDO31753.1 - 2.4 8.3 5.0 3.8 7.6 0.2 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF1707) PX PF00787.24 KDO31754.1 - 2e-18 66.4 0.0 8.2e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 PX domain WW PF00397.26 KDO31754.1 - 1e-05 25.5 1.0 2.1e-05 24.5 1.0 1.5 1 0 0 1 1 1 1 WW domain DnaJ PF00226.31 KDO31754.1 - 0.0023 18.0 0.0 0.0069 16.5 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain YqfQ PF14181.6 KDO31754.1 - 0.65 10.2 3.8 1.6 8.9 3.8 1.6 1 0 0 1 1 1 0 YqfQ-like protein DUF1460 PF07313.12 KDO31754.1 - 1 8.7 6.0 0.27 10.6 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) FYVE PF01363.21 KDO31755.1 - 9.3e-10 38.5 6.2 1.6e-09 37.7 6.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO31755.1 - 0.59 10.4 5.7 1.1 9.5 5.7 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger NOB1_Zn_bind PF08772.11 KDO31755.1 - 5.5 7.2 12.5 0.83 9.9 7.0 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TauD PF02668.16 KDO31756.1 - 1.8e-34 119.8 0.9 5.3e-34 118.2 0.5 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KDO31756.1 - 2e-12 47.6 0.4 2.6e-11 44.0 0.3 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.10 KDO31756.1 - 0.1 11.7 0.6 0.18 10.9 0.1 1.6 2 0 0 2 2 2 0 CsiD H_PPase PF03030.16 KDO31758.1 - 6.6e-253 841.2 37.6 8.6e-253 840.8 37.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase TMEM208_SND2 PF05620.11 KDO31758.1 - 1.3 8.8 5.0 21 4.8 0.4 3.4 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Acyl-CoA_dh_1 PF00441.24 KDO31759.1 - 1.1e-43 149.0 0.3 1.8e-43 148.3 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KDO31759.1 - 5.1e-32 110.9 0.0 2.2e-31 108.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KDO31759.1 - 9e-24 83.5 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KDO31759.1 - 1.3e-17 64.3 0.0 2.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 KDO31760.1 - 3.1e-19 69.0 0.0 5e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KDO31760.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain Zf_RING PF16744.5 KDO31760.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger DEC-1_N PF04625.13 KDO31760.1 - 2 7.4 10.2 3.2 6.7 10.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Dpy-30 PF05186.13 KDO31761.1 - 1.5e-05 24.6 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Dpy-30 motif DUF1851 PF08906.11 KDO31761.1 - 0.026 14.5 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) DFRP_C PF16543.5 KDO31763.1 - 2.7e-21 75.9 2.7 2.7e-21 75.9 2.7 4.0 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KDO31763.1 - 1.2e-05 25.1 0.6 1.2e-05 25.1 0.6 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KDO31763.1 - 0.00016 21.4 0.9 0.00016 21.4 0.9 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO31763.1 - 0.0072 16.3 5.0 0.0072 16.3 5.0 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 KDO31763.1 - 0.022 15.0 0.8 0.022 15.0 0.8 3.1 2 1 1 3 3 3 0 Zinc-finger containing family Torus PF16131.5 KDO31763.1 - 0.24 12.1 21.6 1.5 9.6 10.6 3.9 2 1 1 3 3 3 0 Torus domain MMR1 PF08505.10 KDO31763.1 - 3.5 7.8 12.2 2.7 8.2 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein zf-CCCH_2 PF14608.6 KDO31763.1 - 7.1 7.3 13.5 2.5 8.7 4.3 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Flavoprotein PF02441.19 KDO31764.1 - 5.3e-47 159.5 0.2 6e-47 159.3 0.2 1.0 1 0 0 1 1 1 1 Flavoprotein NAD_binding_7 PF13241.6 KDO31764.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Nup88 PF10168.9 KDO31765.1 - 1.4e-05 23.2 12.0 6.2e-05 21.0 9.0 2.7 2 1 1 3 3 3 1 Nuclear pore component Spc7 PF08317.11 KDO31765.1 - 0.086 11.7 5.6 0.15 10.9 5.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 KDO31765.1 - 0.18 10.4 3.0 0.26 9.9 3.0 1.2 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 KDO31765.1 - 0.19 9.6 9.1 2.1 6.2 1.3 2.1 1 1 1 2 2 2 0 Prominin DUF2205 PF10224.9 KDO31765.1 - 0.26 11.3 1.9 0.43 10.6 0.8 1.9 2 0 0 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 KDO31765.1 - 0.44 10.3 5.6 0.11 12.3 1.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Spectrin PF00435.21 KDO31765.1 - 1 9.9 4.3 1.5 9.3 2.0 2.3 1 1 1 2 2 2 0 Spectrin repeat ADIP PF11559.8 KDO31765.1 - 1.1 9.3 8.2 1.4 9.0 6.7 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Herpes_UL14 PF03580.14 KDO31767.1 - 0.34 11.1 1.1 0.93 9.7 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL14-like protein VPS28 PF03997.12 KDO31768.1 - 2.3e-63 213.3 0.0 2.7e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein PRP38 PF03371.15 KDO31768.1 - 0.066 13.1 0.0 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 PRP38 family Helicase_C_3 PF13625.6 KDO31768.1 - 0.092 12.9 0.6 2.7 8.2 0.1 2.2 1 1 1 2 2 2 0 Helicase conserved C-terminal domain ATPgrasp_N PF18130.1 KDO31768.1 - 0.11 13.0 0.0 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp N-terminal domain MatE PF01554.18 KDO31770.1 - 2.7e-55 186.4 32.8 5.4e-28 97.7 8.4 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KDO31770.1 - 0.0005 20.1 15.3 0.0005 20.1 15.3 4.1 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DYW_deaminase PF14432.6 KDO31771.1 - 1.1e-14 54.3 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases CagZ PF09053.10 KDO31771.1 - 0.23 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 CagZ SBP_bac_1 PF01547.25 KDO31772.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein zf-H2C2_2 PF13465.6 KDO31772.1 - 0.048 14.1 0.1 0.083 13.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double domain KleE PF17394.2 KDO31772.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein HSF_DNA-bind PF00447.17 KDO31773.1 - 1.5e-20 73.5 0.1 2.2e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding BT1 PF03092.16 KDO31774.1 - 7.8e-10 37.6 1.0 7.8e-10 37.6 1.0 2.2 2 0 0 2 2 2 1 BT1 family Imm17 PF15562.6 KDO31774.1 - 0.046 13.6 1.7 0.26 11.2 1.7 2.4 1 0 0 1 1 1 0 Immunity protein 17 Kinesin PF00225.23 KDO31775.1 - 1.6e-65 221.3 0.0 2.2e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO31775.1 - 4.3e-13 49.4 0.0 8.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 KDO31775.1 - 0.0062 16.3 0.4 0.013 15.3 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO31775.1 - 0.0077 16.0 0.1 0.35 10.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KDO31775.1 - 0.025 13.8 0.1 0.062 12.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KDO31775.1 - 0.08 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KDO31775.1 - 0.096 13.1 0.1 0.21 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KDO31775.1 - 0.11 12.8 0.3 0.43 10.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain Dpy-30 PF05186.13 KDO31777.1 - 1.9e-10 40.2 0.4 1.9e-10 40.2 0.4 1.9 2 0 0 2 2 2 1 Dpy-30 motif NEMP PF10225.9 KDO31777.1 - 0.33 10.6 0.6 2.3 7.8 0.0 2.4 2 1 1 3 3 3 0 NEMP family NUDIX PF00293.28 KDO31778.1 - 2.7e-16 59.8 0.0 5.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain OTU PF02338.19 KDO31780.1 - 0.00013 22.4 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 KDO31780.1 - 0.0022 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Lactamase_B PF00753.27 KDO31781.1 - 1e-16 61.5 0.5 2e-16 60.6 0.2 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO31781.1 - 2.8e-05 23.7 0.3 3.4e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KDO31781.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KDO31781.1 - 0.063 13.2 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Carb_anhydrase PF00194.21 KDO31782.1 - 3.6e-15 56.2 0.0 9.8e-15 54.8 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MFS_1 PF07690.16 KDO31784.1 - 2.3e-26 92.5 44.7 3.1e-21 75.7 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO31784.1 - 8.4e-11 41.4 4.5 8.4e-11 41.4 4.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO31785.1 - 6.4e-26 91.1 45.9 1.4e-18 67.0 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO31785.1 - 4e-07 29.3 8.8 4e-07 29.3 8.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KDO31785.1 - 1e-05 24.6 0.0 4.4e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KDO31786.1 - 3.2e-31 108.5 46.2 4.3e-24 85.1 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO31786.1 - 1.8e-10 40.3 11.4 1.8e-10 40.3 11.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO31787.1 - 8.5e-27 94.0 42.1 6.7e-21 74.6 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO31787.1 - 2.8e-12 46.2 7.7 2.8e-12 46.2 7.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KDO31787.1 - 0.017 14.0 10.5 0.15 10.9 10.5 2.2 1 1 0 1 1 1 0 MFS_1 like family BBS2_Mid PF14783.6 KDO31788.1 - 0.00067 19.7 0.0 0.0067 16.5 0.0 2.6 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region Cupin_7 PF12973.7 KDO31789.1 - 1.8e-34 117.5 0.0 3.2e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 ChrR Cupin-like domain Cupin_2 PF07883.11 KDO31789.1 - 1.5e-05 24.6 0.3 0.0026 17.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain DUF4437 PF14499.6 KDO31789.1 - 0.0017 17.5 0.0 0.044 12.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4437) DMSP_lyase PF16867.5 KDO31789.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 KDO31789.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Cupin NUC153 PF08159.12 KDO31790.1 - 1.1e-09 37.9 1.7 2.3e-09 36.9 1.7 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 KDO31790.1 - 0.00082 19.6 0.0 0.026 14.8 0.0 2.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO31790.1 - 0.0025 18.6 0.1 90 4.2 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat CDC45 PF02724.14 KDO31790.1 - 3.2 5.9 10.8 5.1 5.3 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PI3_PI4_kinase PF00454.27 KDO31791.1 - 3e-48 164.8 0.0 1.8e-46 159.0 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KDO31791.1 - 2.1e-37 128.4 0.8 4.9e-37 127.1 0.8 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 KDO31791.1 - 1.1e-18 67.6 1.9 1.6e-11 44.6 0.6 2.8 2 0 0 2 2 2 2 PH domain PI3K_C2 PF00792.24 KDO31791.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KDO31791.1 - 0.00032 20.8 0.1 0.0008 19.5 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PH_4 PF15404.6 KDO31791.1 - 0.01 15.6 0.3 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KDO31791.1 - 0.013 16.0 1.4 0.013 16.0 1.4 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4135 PF13575.6 KDO31791.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Glycos_transf_1 PF00534.20 KDO31791.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 PH PF00169.29 KDO31792.1 - 4e-09 36.9 0.0 9.3e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KDO31792.1 - 1.2e-06 28.7 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO31792.1 - 2.6e-05 24.3 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO31792.1 - 0.015 15.7 0.3 0.53 10.7 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 KDO31792.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PI3Ka PF00613.20 KDO31793.1 - 1.3e-45 155.1 0.5 2.6e-45 154.1 0.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 KDO31793.1 - 2.6e-33 114.7 1.3 1.8e-15 57.3 0.0 3.2 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 KDO31793.1 - 2.3e-09 37.4 0.2 0.00015 22.0 0.0 3.4 4 0 0 4 4 3 2 Pleckstrin homology domain PH_11 PF15413.6 KDO31793.1 - 7.8e-09 35.9 4.2 0.00079 19.8 0.2 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain PI3K_rbd PF00794.18 KDO31793.1 - 6.4e-08 32.7 0.2 2.4e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KDO31793.1 - 4.1e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PH_13 PF16652.5 KDO31793.1 - 0.0002 21.2 0.3 0.27 11.0 0.2 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KDO31793.1 - 0.00098 19.2 0.7 0.83 9.8 0.0 2.9 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 KDO31793.1 - 0.00099 19.5 1.4 0.013 15.8 0.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 KDO31793.1 - 0.0046 16.8 0.6 0.018 14.9 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KDO31793.1 - 0.017 15.5 0.2 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_12 PF16457.5 KDO31793.1 - 0.049 14.2 0.5 0.66 10.5 0.3 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 KDO31793.1 - 0.072 13.4 0.0 29 5.0 0.0 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain PI3_PI4_kinase PF00454.27 KDO31794.1 - 1e-45 156.5 0.0 2.9e-44 151.8 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KDO31794.1 - 6.3e-45 152.9 1.1 1.2e-44 151.9 1.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 KDO31794.1 - 8e-24 84.2 3.1 1.3e-10 41.8 0.1 3.4 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 KDO31794.1 - 5e-09 36.5 7.5 0.00026 21.4 0.8 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KDO31794.1 - 1.5e-05 25.2 6.9 0.039 14.2 3.8 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PI3K_C2 PF00792.24 KDO31794.1 - 6.8e-05 22.8 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PH_9 PF15410.6 KDO31794.1 - 0.00032 21.1 6.0 0.078 13.4 2.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH_4 PF15404.6 KDO31794.1 - 0.00084 19.2 0.7 0.098 12.4 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3136 PF11334.8 KDO31794.1 - 0.0043 16.8 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3136) DUF4135 PF13575.6 KDO31794.1 - 0.048 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3K_rbd PF00794.18 KDO31794.1 - 0.077 13.2 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain MFS_1 PF07690.16 KDO31795.1 - 3.2e-20 72.4 21.0 6e-20 71.5 21.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TrkH PF02386.16 KDO31795.1 - 0.2 10.0 3.6 0.089 11.2 0.4 1.9 2 0 0 2 2 2 0 Cation transport protein Peptidase_C1 PF00112.23 KDO31796.1 - 1.3e-06 28.7 0.1 1.5e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease PX PF00787.24 KDO31797.1 - 7.6e-06 25.9 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PX domain PCIF1_WW PF12237.8 KDO31797.1 - 0.034 13.8 0.0 0.091 12.4 0.0 1.7 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain F-box PF00646.33 KDO31797.1 - 0.092 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain SMC_hinge PF06470.13 KDO31797.1 - 0.093 13.0 0.0 0.56 10.5 0.0 2.3 2 1 1 3 3 3 0 SMC proteins Flexible Hinge Domain PI3Ka PF00613.20 KDO31800.1 - 3.4e-45 153.7 0.2 6.8e-45 152.7 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KDO31800.1 - 8.6e-41 140.4 0.4 4e-26 92.4 0.0 2.9 3 0 0 3 3 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 KDO31800.1 - 4.8e-30 104.2 8.0 1.4e-14 54.5 0.3 3.1 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 KDO31800.1 - 4.2e-11 43.2 8.9 7.1e-06 26.4 1.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PI3K_C2 PF00792.24 KDO31800.1 - 3.6e-07 30.2 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KDO31800.1 - 3.6e-06 27.1 0.1 9.8e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PH_8 PF15409.6 KDO31800.1 - 2.6e-05 24.4 6.7 0.056 13.7 4.4 3.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KDO31800.1 - 0.00021 21.6 5.6 0.058 13.8 0.4 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH_4 PF15404.6 KDO31800.1 - 0.014 15.2 3.9 0.13 12.0 0.4 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain BLOC1S3 PF15753.5 KDO31800.1 - 0.039 14.1 0.4 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 PH_2 PF08458.10 KDO31800.1 - 0.057 13.8 1.3 5.3 7.4 0.2 2.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 KDO31800.1 - 0.068 13.3 4.0 0.069 13.3 0.4 2.5 3 0 0 3 3 2 0 Meiotic cell cortex C-terminal pleckstrin homology DUF2096 PF09869.9 KDO31800.1 - 0.072 13.2 1.3 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) PH_12 PF16457.5 KDO31800.1 - 2.5 8.6 10.8 0.9 10.1 1.4 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain PI3Ka PF00613.20 KDO31801.1 - 2.2e-45 154.4 0.1 4e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KDO31801.1 - 4.7e-43 147.8 0.0 2.8e-41 142.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 KDO31801.1 - 5.6e-31 107.2 5.6 1.5e-16 60.8 0.3 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO31801.1 - 4.4e-08 33.5 11.3 0.00069 20.0 0.4 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PI3K_C2 PF00792.24 KDO31801.1 - 2.3e-07 30.8 0.0 4.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KDO31801.1 - 6.5e-07 29.5 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PH_8 PF15409.6 KDO31801.1 - 1.2e-06 28.7 7.4 0.074 13.3 0.0 4.7 4 1 0 4 4 4 2 Pleckstrin homology domain PH_13 PF16652.5 KDO31801.1 - 0.036 13.9 1.2 4.1 7.2 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4135 PF13575.6 KDO31801.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PH_2 PF08458.10 KDO31801.1 - 0.22 11.9 0.8 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PBP1_TM PF14812.6 KDO31801.1 - 0.35 11.3 4.0 7.3 7.0 0.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3_PI4_kinase PF00454.27 KDO31802.1 - 7.6e-45 153.7 0.0 1.6e-43 149.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 KDO31802.1 - 2e-25 89.3 0.0 8e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 PH domain PI3Ka PF00613.20 KDO31802.1 - 4.4e-24 84.9 0.0 7.7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH_11 PF15413.6 KDO31802.1 - 5.5e-09 36.4 0.0 0.0014 19.1 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PI3K_C2 PF00792.24 KDO31802.1 - 4.6e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PH_8 PF15409.6 KDO31802.1 - 0.0066 16.7 1.3 0.044 14.1 0.0 3.0 4 0 0 4 4 4 1 Pleckstrin homology domain PH_4 PF15404.6 KDO31802.1 - 0.014 15.2 0.0 15 5.3 0.0 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 KDO31802.1 - 0.083 12.7 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.29 KDO31803.1 - 6.1e-05 23.5 0.0 0.00026 21.5 0.0 2.0 2 1 1 3 3 3 1 PH domain Zn-ribbon_8 PF09723.10 KDO31804.1 - 0.0033 17.5 1.7 0.0075 16.4 1.7 1.5 1 0 0 1 1 1 1 Zinc ribbon domain PDZ_6 PF17820.1 KDO31804.1 - 0.0097 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO31804.1 - 0.011 16.0 0.1 0.02 15.2 0.1 1.3 1 0 0 1 1 1 0 PDZ domain Ribosomal_L32p PF01783.23 KDO31804.1 - 0.022 15.0 0.7 0.049 13.9 0.7 1.6 1 0 0 1 1 1 0 Ribosomal L32p protein family HypA PF01155.19 KDO31804.1 - 0.025 14.6 0.2 0.05 13.6 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KDO31804.1 - 0.035 14.1 2.1 0.08 13.0 2.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon PPR PF01535.20 KDO31804.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 PPR repeat PPR_2 PF13041.6 KDO31804.1 - 0.047 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family OrfB_Zn_ribbon PF07282.11 KDO31804.1 - 0.064 13.2 1.3 0.13 12.2 1.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.13 KDO31804.1 - 0.076 12.7 3.7 1.2 8.9 3.7 2.4 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 KDO31804.1 - 0.15 11.8 0.7 6.1 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KDO31804.1 - 0.25 10.8 3.6 0.74 9.3 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 KDO31804.1 - 0.27 11.4 1.1 4.3 7.5 1.4 2.3 1 1 1 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Prok-RING_1 PF14446.6 KDO31804.1 - 0.52 10.3 3.8 0.41 10.6 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DENN PF02141.21 KDO31805.1 - 2e-26 93.1 1.6 2e-26 93.1 0.4 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KDO31805.1 - 5.1e-08 33.6 0.9 1.4e-07 32.2 0.6 2.0 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 KDO31805.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 dDENN domain LRR_6 PF13516.6 KDO31806.1 - 2.6e-07 30.1 2.3 4.9 7.5 0.0 6.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.6 KDO31806.1 - 0.017 14.6 0.3 0.44 10.0 0.4 2.3 1 1 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KDO31806.1 - 0.061 13.9 0.5 20 6.2 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO31806.1 - 0.068 13.6 8.7 6.7 7.3 0.1 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO31806.1 - 0.31 10.8 7.0 29 4.5 0.4 5.0 3 1 1 4 4 4 0 Leucine rich repeat Pro-kuma_activ PF09286.11 KDO31807.1 - 1.5e-19 70.7 0.0 2.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KDO31807.1 - 2.7e-05 23.6 0.5 5.4e-05 22.6 0.5 1.5 1 0 0 1 1 1 1 Subtilase family PEP-CTERM PF07589.11 KDO31807.1 - 2.7 8.2 7.2 0.39 10.9 2.8 2.0 2 0 0 2 2 2 0 PEP-CTERM motif PLAC8 PF04749.17 KDO31808.1 - 8.7e-15 55.5 3.6 1.1e-14 55.2 3.6 1.1 1 0 0 1 1 1 1 PLAC8 family YbjM PF11045.8 KDO31808.1 - 0.19 11.9 3.7 0.34 11.1 3.5 1.6 1 1 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Peptidase_U4 PF03419.13 KDO31808.1 - 0.33 10.2 3.6 1.1 8.5 1.9 1.8 1 1 1 2 2 2 0 Sporulation factor SpoIIGA FAD_binding_1 PF00667.20 KDO31809.1 - 1.7e-40 139.0 0.0 3.3e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KDO31809.1 - 5.2e-26 91.6 0.0 8.7e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KDO31809.1 - 2.2e-15 57.2 0.0 5.5e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KDO31809.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain ANAPC4_WD40 PF12894.7 KDO31811.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KDO31813.1 - 5e-62 209.6 0.0 6.7e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31813.1 - 2.3e-26 92.6 0.0 3.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 KDO31813.1 - 1.5e-06 28.2 0.8 1.9e-05 24.6 0.1 2.7 2 0 0 2 2 2 1 WW domain DUF588 PF04535.12 KDO31813.1 - 0.0021 17.9 2.4 0.0021 17.8 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF588) Haspin_kinase PF12330.8 KDO31813.1 - 0.034 13.1 0.2 0.055 12.4 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Epimerase PF01370.21 KDO31814.1 - 8.1e-23 81.1 0.1 1.1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KDO31814.1 - 3.5e-11 42.8 0.3 5.7e-11 42.0 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KDO31814.1 - 1.5e-10 41.0 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KDO31814.1 - 1.7e-10 40.4 0.0 4.2e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KDO31814.1 - 6.3e-10 39.2 0.5 2.2e-09 37.5 0.5 2.0 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KDO31814.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KDO31814.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KDO31814.1 - 0.092 13.0 0.1 0.18 12.0 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KDO31814.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 KDO31814.1 - 0.12 11.6 0.1 0.32 10.1 0.1 1.9 1 1 0 1 1 1 0 Male sterility protein Lectin_leg-like PF03388.13 KDO31814.1 - 0.19 11.1 0.0 29 3.9 0.0 3.0 3 0 0 3 3 3 0 Legume-like lectin family Pkinase PF00069.25 KDO31815.1 - 5.7e-61 206.2 0.0 7.7e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31815.1 - 2.9e-47 161.2 0.1 3.8e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO31815.1 - 1.4e-05 24.1 0.0 4.8e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO31815.1 - 0.0027 16.7 1.2 0.0062 15.5 1.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO31815.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO31815.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO31815.1 - 0.042 13.2 0.1 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KDO31815.1 - 0.064 12.8 0.3 0.15 11.6 0.3 1.6 1 1 0 1 1 1 0 RIO1 family KAAG1 PF15354.6 KDO31816.1 - 0.22 12.1 4.4 0.42 11.2 0.2 2.9 2 0 0 2 2 2 0 Kidney-associated antigen 1 Sensor PF13796.6 KDO31816.1 - 0.78 9.8 9.3 1 9.4 6.3 2.2 1 1 1 2 2 2 0 Putative sensor Integrin_alpha PF00357.20 KDO31817.1 - 0.35 10.9 0.9 0.9 9.7 0.9 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region LRR_8 PF13855.6 KDO31818.1 - 0.00025 20.8 11.0 0.029 14.1 0.0 4.3 3 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KDO31818.1 - 0.15 12.5 11.3 0.31 11.5 4.6 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) FYVE PF01363.21 KDO31819.1 - 3.8e-12 46.2 10.1 8e-12 45.1 10.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE PF01363.21 KDO31820.1 - 5.3e-09 36.1 19.9 1e-08 35.2 19.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger Band_7 PF01145.25 KDO31822.1 - 5.5e-27 94.9 0.9 1.1e-26 93.9 0.9 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family LRR_8 PF13855.6 KDO31823.1 - 1.2e-06 28.1 8.8 0.0014 18.3 0.0 4.1 3 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KDO31823.1 - 0.045 14.2 11.8 0.2 12.1 4.7 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) FYVE PF01363.21 KDO31824.1 - 5.2e-08 32.9 11.8 8.6e-08 32.2 11.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger DUF1677 PF07911.13 KDO31824.1 - 0.22 11.9 3.7 0.62 10.5 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) Rpr2 PF04032.16 KDO31824.1 - 0.48 10.7 3.5 1 9.7 3.5 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GAF PF01590.26 KDO31825.1 - 2.1e-07 31.6 1.1 3.4e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 GAF domain FYVE PF01363.21 KDO31825.1 - 4.5e-07 29.9 17.5 1e-06 28.8 17.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 KDO31825.1 - 0.00025 21.3 0.0 0.00047 20.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain Opy2 PF09463.10 KDO31825.1 - 0.13 12.6 9.3 0.4 11.1 1.1 3.0 2 0 0 2 2 2 0 Opy2 protein FYVE_2 PF02318.16 KDO31825.1 - 0.72 10.1 9.7 1.6 8.9 9.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ras PF00071.22 KDO31826.1 - 5.8e-64 214.6 0.6 6.8e-64 214.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO31826.1 - 3.9e-36 123.9 0.1 5.8e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO31826.1 - 8.7e-16 57.9 0.0 1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO31826.1 - 2.3e-06 27.7 0.0 3.9e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO31826.1 - 4.8e-05 22.8 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO31826.1 - 0.00013 22.0 0.3 0.069 13.1 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KDO31826.1 - 0.00013 21.6 0.3 0.00061 19.4 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO31826.1 - 0.00087 18.8 0.5 0.0012 18.3 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KDO31826.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain CENP-M PF11111.8 KDO31826.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_16 PF13191.6 KDO31826.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KDO31826.1 - 0.066 13.7 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KDO31826.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 KDO31826.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KDO31826.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Med8 PF10232.9 KDO31827.1 - 8.3e-11 41.9 9.2 2.2e-10 40.6 9.2 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Peptidase_M48 PF01435.18 KDO31828.1 - 7.7e-26 91.1 0.0 2.1e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 Reprolysin_3 PF13582.6 KDO31828.1 - 0.022 15.3 0.1 0.058 13.9 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Imm75 PF15660.6 KDO31828.1 - 0.094 13.0 0.4 23 5.3 0.0 2.8 3 0 0 3 3 3 0 Putative Immunity protein 75 NCD3G PF07562.14 KDO31830.1 - 0.084 12.9 2.8 1.4 8.9 0.3 2.2 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Trypan_PARP PF05887.11 KDO31832.1 - 6.8e-05 22.9 14.7 6.8e-05 22.9 14.7 1.9 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 KDO31832.1 - 0.0026 18.3 23.3 0.0066 17.0 23.3 1.6 1 0 0 1 1 1 1 TonB polyproline region GIDE PF12483.8 KDO31832.1 - 0.19 11.1 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 E3 Ubiquitin ligase DUF4106 PF13388.6 KDO31832.1 - 8.7 5.5 7.4 11 5.1 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Nucleo_P87 PF07267.11 KDO31832.1 - 8.9 5.0 6.9 12 4.6 6.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DHHC PF01529.20 KDO31833.1 - 1.4e-22 80.3 5.1 1.4e-22 80.3 5.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase OSTbeta PF15048.6 KDO31833.1 - 0.38 10.9 0.9 0.66 10.1 0.9 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2897 PF11446.8 KDO31833.1 - 1.1 9.1 2.8 2.1 8.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Laminin_I PF06008.14 KDO31834.1 - 0.011 15.5 1.4 0.014 15.2 1.4 1.3 1 1 0 1 1 1 0 Laminin Domain I Prefoldin_2 PF01920.20 KDO31834.1 - 0.063 13.2 0.8 7.7 6.5 0.0 2.3 2 1 0 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 KDO31834.1 - 0.068 12.2 1.4 0.098 11.7 0.2 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KDO31834.1 - 0.073 13.1 1.7 0.36 10.9 1.7 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.16 KDO31836.1 - 6.7e-28 97.6 35.7 1.3e-17 63.8 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KDO31839.1 - 1.4e-28 98.5 38.2 0.0001 23.0 0.1 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31839.1 - 7.6e-13 48.6 6.1 0.017 15.4 0.3 7.9 2 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO31839.1 - 0.00055 18.7 5.3 0.045 12.4 0.1 4.0 4 1 0 5 5 5 2 Nucleoporin Nup120/160 Hira PF07569.11 KDO31839.1 - 0.00076 19.3 7.1 1.3 8.7 0.6 5.7 4 2 0 5 5 5 1 TUP1-like enhancer of split BBS2_Mid PF14783.6 KDO31839.1 - 0.0021 18.1 0.0 2.6 8.1 0.0 4.5 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 KDO31839.1 - 0.2 10.6 10.2 3.4 6.5 0.9 4.6 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Exo84_C PF16528.5 KDO31840.1 - 4.1e-12 46.3 0.1 1.2e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KDO31840.1 - 7e-11 42.1 1.4 2.6e-10 40.2 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 PH PF00169.29 KDO31840.1 - 1.4e-08 35.2 0.0 4.7e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO31840.1 - 3.4e-05 24.2 0.0 0.00011 22.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain COG5 PF10392.9 KDO31840.1 - 0.04 14.1 0.6 0.04 14.1 0.6 2.4 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DEP PF00610.21 KDO31840.1 - 0.14 12.2 0.0 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NYD-SP28 PF14772.6 KDO31840.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 Sperm tail zf-RING_2 PF13639.6 KDO31841.1 - 1.4e-10 41.3 7.2 2.6e-10 40.5 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO31841.1 - 5e-09 35.9 8.9 1e-08 34.8 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO31841.1 - 4e-07 29.7 4.5 4e-07 29.7 4.5 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO31841.1 - 1e-06 28.5 6.3 1.8e-06 27.8 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KDO31841.1 - 1.4e-06 28.1 7.4 2.5e-06 27.2 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO31841.1 - 1e-05 25.4 6.1 2.6e-05 24.1 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO31841.1 - 1.4e-05 24.8 9.6 2.3e-05 24.1 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO31841.1 - 3.5e-05 24.0 5.3 9.1e-05 22.7 5.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain PHD PF00628.29 KDO31841.1 - 0.0094 15.8 6.5 0.018 14.9 6.5 1.5 1 0 0 1 1 1 1 PHD-finger TRAF_BIRC3_bd PF16673.5 KDO31841.1 - 0.041 13.7 0.5 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain CENP-F_leu_zip PF10473.9 KDO31841.1 - 0.051 13.6 7.3 0.096 12.7 7.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KDO31841.1 - 0.056 14.1 3.8 0.8 10.4 2.7 2.4 2 0 0 2 2 2 0 Initiation control protein YabA zf-C3H2C3 PF17122.5 KDO31841.1 - 0.059 13.4 8.1 0.11 12.6 8.1 1.4 1 0 0 1 1 1 0 Zinc-finger CEP63 PF17045.5 KDO31841.1 - 0.065 13.1 5.8 0.09 12.7 5.8 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa TolA_bind_tri PF16331.5 KDO31841.1 - 0.1 12.7 9.2 0.49 10.5 5.7 2.9 2 1 0 2 2 2 0 TolA binding protein trimerisation zf-RING-like PF08746.11 KDO31841.1 - 0.12 12.7 6.3 0.19 12.0 6.3 1.4 1 0 0 1 1 1 0 RING-like domain DUF724 PF05266.14 KDO31841.1 - 0.13 12.0 6.8 0.19 11.5 4.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) C1_1 PF00130.22 KDO31841.1 - 0.21 11.5 7.2 0.079 12.9 3.1 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) APC_N_CC PF16689.5 KDO31841.1 - 0.22 11.6 3.8 0.14 12.3 0.8 2.3 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain V_ATPase_I PF01496.19 KDO31841.1 - 0.4 8.5 2.7 0.48 8.3 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_ribbon_17 PF17120.5 KDO31841.1 - 0.46 10.1 8.7 0.81 9.4 8.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TMF_TATA_bd PF12325.8 KDO31841.1 - 0.55 10.5 10.4 0.24 11.6 5.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Zn-ribbon_8 PF09723.10 KDO31841.1 - 0.73 10.0 5.3 2.2 8.5 5.3 1.8 1 0 0 1 1 1 0 Zinc ribbon domain ATG16 PF08614.11 KDO31841.1 - 0.78 9.9 12.6 7.4 6.7 0.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KDO31841.1 - 1 9.4 12.5 11 6.1 7.7 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 KDO31841.1 - 1.1 9.0 9.9 1.4 8.7 8.9 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Fez1 PF06818.15 KDO31841.1 - 2.6 8.4 9.7 4.8 7.6 9.6 1.4 1 1 0 1 1 1 0 Fez1 SlyX PF04102.12 KDO31841.1 - 2.9 8.6 9.6 15 6.2 2.0 3.2 2 1 1 3 3 3 0 SlyX Cep57_CLD_2 PF14197.6 KDO31841.1 - 3.7 7.7 7.2 0.33 11.1 1.7 2.0 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 Prok-RING_1 PF14446.6 KDO31841.1 - 7.4 6.6 11.2 0.4 10.7 2.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HAUS-augmin3 PF14932.6 KDO31841.1 - 7.7 6.0 13.6 3 7.4 10.2 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 T3SS_needle_E PF08988.10 KDO31841.1 - 7.8 6.7 12.6 7.9 6.7 3.0 2.9 1 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle AAA_16 PF13191.6 KDO31842.1 - 3e-06 27.7 1.9 0.00016 22.1 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KDO31842.1 - 5.7e-06 26.8 0.1 3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KDO31842.1 - 0.00093 19.1 0.1 0.87 9.5 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_5 PF07728.14 KDO31842.1 - 0.002 18.1 0.0 0.0071 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KDO31842.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KDO31842.1 - 0.015 15.4 0.0 0.056 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KDO31842.1 - 0.017 15.7 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KDO31842.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO31842.1 - 0.036 14.0 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KDO31842.1 - 0.043 13.5 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO31842.1 - 0.062 13.7 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 KDO31842.1 - 0.076 12.8 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain KTI12 PF08433.10 KDO31842.1 - 0.093 12.2 0.1 5.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 KDO31842.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KDO31842.1 - 0.1 12.0 0.1 2.6 7.4 0.1 2.7 2 1 0 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 KDO31842.1 - 0.12 11.6 0.0 0.38 10.0 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 KDO31842.1 - 0.2 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Adeno_E3_CR2 PF02439.15 KDO31843.1 - 0.0055 16.4 1.6 0.0084 15.9 1.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KDO31843.1 - 0.0078 17.1 0.0 0.011 16.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2561 PF10812.8 KDO31843.1 - 0.0081 16.2 1.2 0.011 15.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) RCR PF12273.8 KDO31843.1 - 0.01 16.5 0.1 0.013 16.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red LapA_dom PF06305.11 KDO31843.1 - 0.027 14.3 1.2 0.042 13.7 1.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 KDO31843.1 - 0.058 13.6 0.1 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PTP_tm PF18861.1 KDO31843.1 - 0.11 12.5 0.7 0.17 11.9 0.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 KDO31843.1 - 0.21 10.4 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.9 KDO31843.1 - 0.25 10.1 0.2 0.33 9.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KDO31843.1 - 0.29 11.0 0.8 0.6 10.0 0.3 1.7 2 0 0 2 2 2 0 TMEM154 protein family CD34_antigen PF06365.12 KDO31843.1 - 0.31 10.6 0.2 0.45 10.1 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family NCU-G1 PF15065.6 KDO31843.1 - 0.4 9.6 3.7 0.12 11.4 1.0 1.4 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 RyR PF02026.16 KDO31844.1 - 1.5e-60 201.4 0.1 1e-28 99.3 0.0 2.8 2 0 0 2 2 2 2 RyR domain PKD_channel PF08016.12 KDO31844.1 - 7.8e-48 163.2 15.6 1.5e-47 162.2 15.6 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KDO31844.1 - 9.5e-14 51.2 25.0 9.5e-14 51.2 25.0 1.9 2 0 0 2 2 2 1 Ion transport protein DUF1129 PF06570.11 KDO31844.1 - 0.22 11.0 4.9 0.19 11.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2370 PF10176.9 KDO31844.1 - 0.34 10.5 3.1 0.46 10.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) Ank_2 PF12796.7 KDO31845.1 - 2e-42 143.6 18.4 1.5e-08 35.1 0.2 8.5 5 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31845.1 - 1.4e-31 108.5 23.7 4.2e-06 27.2 0.1 10.8 9 3 3 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO31845.1 - 4.9e-30 103.2 20.3 0.00016 21.9 0.1 10.3 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31845.1 - 2.2e-22 76.7 23.1 0.0096 16.4 0.0 13.6 14 1 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 KDO31845.1 - 1.2e-16 60.3 35.9 0.0042 17.5 0.0 12.5 13 0 0 13 13 13 5 Ankyrin repeat Ion_trans PF00520.31 KDO31845.1 - 6.3e-14 51.8 19.4 9.5e-14 51.2 19.4 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KDO31845.1 - 0.0024 16.6 16.0 0.0024 16.6 16.0 1.8 1 1 1 2 2 2 1 Polycystin cation channel GLE1 PF07817.13 KDO31845.1 - 0.15 11.3 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 GLE1-like protein 2OG-FeII_Oxy PF03171.20 KDO31846.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KDO31846.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Hemerythrin PF01814.23 KDO31849.1 - 1.8e-10 41.6 12.4 2.5e-10 41.1 9.3 2.1 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Adeno_E1B_19K PF01691.16 KDO31849.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 1 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen EMP24_GP25L PF01105.24 KDO31850.1 - 1.1e-49 168.9 0.3 1.3e-49 168.6 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KDO31850.1 - 0.065 13.5 0.1 0.093 13.0 0.1 1.3 1 0 0 1 1 1 0 SdrD B-like domain Phage_hub_GP28 PF11110.8 KDO31850.1 - 0.076 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Baseplate hub distal subunit EF-hand_1 PF00036.32 KDO31851.1 - 7.4e-30 100.3 6.4 3.2e-05 23.1 0.0 6.4 7 0 0 7 7 7 5 EF hand EF-hand_6 PF13405.6 KDO31851.1 - 6.8e-26 88.0 3.5 0.00034 20.3 0.1 6.3 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 KDO31851.1 - 2.8e-25 88.6 1.6 3.4e-09 37.0 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO31851.1 - 8.4e-25 85.1 5.3 9.7e-05 21.7 0.0 5.9 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 KDO31851.1 - 1.2e-14 53.9 10.3 0.00016 21.5 0.1 5.8 4 1 1 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO31851.1 - 0.00018 21.8 0.0 0.47 10.8 0.1 3.4 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO31851.1 - 0.00063 20.0 2.0 0.082 13.3 0.0 3.7 3 1 1 4 4 4 1 EF-hand domain EF-hand_4 PF12763.7 KDO31851.1 - 0.0036 17.2 0.0 0.35 10.9 0.0 3.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KDO31851.1 - 0.014 15.3 0.3 17 5.3 0.0 3.7 2 1 1 3 3 3 0 Caleosin related protein PMBR PF09373.10 KDO31851.1 - 0.082 13.1 0.2 0.8 10.0 0.0 2.8 3 0 0 3 3 3 0 Pseudomurein-binding repeat SHOCT PF09851.9 KDO31851.1 - 0.14 11.9 1.6 6.2 6.7 0.4 2.9 2 0 0 2 2 2 0 Short C-terminal domain Ank_4 PF13637.6 KDO31852.1 - 2.9e-39 132.9 30.7 1.1e-05 25.9 0.8 11.8 7 2 4 11 11 11 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31852.1 - 5.5e-34 116.6 20.0 1.1e-07 32.3 0.2 7.3 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO31852.1 - 7.5e-33 112.2 36.5 0.036 14.4 0.1 14.7 4 3 11 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31852.1 - 5.7e-17 60.1 20.7 3.9 8.4 0.0 14.7 16 2 1 17 17 17 3 Ankyrin repeat DUF249 PF03158.13 KDO31852.1 - 0.007 16.1 0.1 9 5.9 0.0 4.2 2 1 2 4 4 4 1 Multigene family 530 protein Cas_Csy1 PF09611.10 KDO31852.1 - 0.032 13.3 0.7 1.6 7.7 0.0 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy1) DUF1979 PF09322.10 KDO31852.1 - 0.043 13.7 0.0 7.4 6.6 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1979) JAB PF01398.21 KDO31852.1 - 0.053 13.5 13.5 2.1 8.4 0.3 5.2 3 1 2 6 6 6 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ank PF00023.30 KDO31852.1 - 0.4 11.2 18.2 42 4.8 0.1 9.0 7 3 1 8 8 8 0 Ankyrin repeat YmaF PF12788.7 KDO31852.1 - 3.4 8.3 30.0 0.47 11.0 1.8 6.6 4 1 6 10 10 10 0 YmaF family PRP38 PF03371.15 KDO31853.1 - 0.058 13.3 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 PRP38 family COX15-CtaA PF02628.15 KDO31854.1 - 2.8e-24 85.8 1.0 3.8e-24 85.4 1.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Coatomer_E PF04733.14 KDO31854.1 - 0.2 11.0 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit Metallophos PF00149.28 KDO31855.1 - 3.1e-05 24.6 0.2 8.1e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ASH PF15780.5 KDO31856.1 - 6.7e-34 116.0 0.3 3.2e-05 24.0 0.0 10.7 11 0 0 11 11 11 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KDO31856.1 - 7.5e-11 41.9 0.0 0.054 13.3 0.0 8.2 10 0 0 10 10 10 2 MSP (Major sperm protein) domain E1-E2_ATPase PF00122.20 KDO31857.1 - 5.7e-38 130.2 0.6 7.9e-37 126.5 0.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KDO31857.1 - 3.5e-11 42.6 0.2 1e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KDO31857.1 - 1.3e-09 38.7 0.3 2.9e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PTS_EIIA_1 PF00358.20 KDO31857.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 CALM_bind PF16025.5 KDO31858.1 - 0.28 11.7 9.5 1.4 9.4 9.4 2.1 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding bZIP_2 PF07716.15 KDO31858.1 - 3 8.0 13.4 0.6 10.2 5.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper FGase PF05013.12 KDO31859.1 - 5.6e-11 43.1 0.0 0.0001 22.6 0.0 2.6 1 1 1 2 2 2 2 N-formylglutamate amidohydrolase Mpv17_PMP22 PF04117.12 KDO31860.1 - 5.4e-12 45.8 1.0 1.1e-11 44.7 1.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mito_carr PF00153.27 KDO31861.1 - 5.4e-61 202.5 6.5 4e-21 74.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KDO31861.1 - 0.00017 20.8 1.7 0.012 14.7 0.1 2.4 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Egh16-like PF11327.8 KDO31861.1 - 0.0081 16.6 0.3 0.077 13.4 0.1 2.2 2 1 0 2 2 2 1 Egh16-like virulence factor Mo25 PF08569.11 KDO31862.1 - 1.7e-62 211.7 0.0 2e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like DUF3412 PF11892.8 KDO31862.1 - 0.059 13.5 0.1 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3412) Tim44 PF04280.15 KDO31863.1 - 0.00061 19.9 0.0 0.0057 16.8 0.0 2.2 3 0 0 3 3 3 1 Tim44-like domain DUF4831 PF16115.5 KDO31863.1 - 0.059 12.4 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) DUF3228 PF11539.8 KDO31864.1 - 2.4e-80 268.6 0.0 2.7e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Tim44 PF04280.15 KDO31866.1 - 7.3e-09 35.9 0.1 3.8e-06 27.1 0.1 2.1 2 0 0 2 2 2 2 Tim44-like domain VASt PF16016.5 KDO31867.1 - 3.4e-21 76.3 0.2 5.7e-21 75.5 0.2 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 KDO31867.1 - 0.00089 19.7 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 PH domain RXT2_N PF08595.11 KDO31867.1 - 0.01 15.9 0.6 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KDO31867.1 - 0.024 14.3 1.2 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 FAM176 family DUF3464 PF11947.8 KDO31867.1 - 0.14 11.9 0.2 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CENP-B_dimeris PF09026.10 KDO31867.1 - 0.25 11.7 12.8 0.24 11.8 0.8 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain bZIP_1 PF00170.21 KDO31868.1 - 0.0017 18.4 10.7 0.004 17.2 10.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO31868.1 - 0.0019 18.2 9.6 0.0054 16.8 9.6 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Nore1-SARAH PF16517.5 KDO31868.1 - 0.0072 16.2 4.0 0.018 14.9 2.0 2.4 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain SLM4 PF16818.5 KDO31868.1 - 0.072 13.0 0.4 0.15 12.0 0.3 1.4 1 1 0 1 1 1 0 Protein SLM4 GIT_CC PF16559.5 KDO31868.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5041 PF16444.5 KDO31868.1 - 0.18 12.1 0.3 0.27 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5041) Isochorismatase PF00857.20 KDO31869.1 - 1.5e-28 100.2 0.2 3.1e-28 99.1 0.2 1.5 1 1 0 1 1 1 1 Isochorismatase family DUF5465 PF17553.2 KDO31869.1 - 5.6 7.8 6.4 31 5.5 1.9 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5465) Peptidase_C69 PF03577.15 KDO31870.1 - 1.2e-41 142.9 0.1 6.1e-41 140.7 0.1 1.9 1 1 0 1 1 1 1 Peptidase family C69 Dockerin_1 PF00404.18 KDO31870.1 - 0.039 14.2 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Dockerin type I domain TPR_1 PF00515.28 KDO31871.1 - 1.8e-06 27.5 0.1 0.00014 21.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31871.1 - 2.3e-06 27.3 0.2 0.00042 20.2 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31871.1 - 0.00064 20.3 0.5 0.00064 20.3 0.5 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.12 KDO31871.1 - 0.068 13.9 0.1 0.32 11.8 0.0 2.1 2 0 0 2 2 2 0 Sel1 repeat TPR_12 PF13424.6 KDO31871.1 - 0.18 12.1 1.5 0.66 10.3 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO31872.1 - 2.8e-07 30.6 0.3 9.7e-07 28.9 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31872.1 - 1.1e-05 25.0 0.0 0.0021 17.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31872.1 - 1.4e-05 24.8 0.0 0.0048 16.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO31872.1 - 0.0024 18.5 0.3 0.0024 18.5 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31872.1 - 0.22 12.4 5.7 1.4 9.9 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 KDO31873.1 - 0.0098 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO31873.1 - 0.011 16.0 0.0 0.044 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KDO31873.1 - 0.024 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VirE PF05272.11 KDO31873.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E SRPRB PF09439.10 KDO31873.1 - 0.092 12.2 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 KDO31873.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HEPN_RES_NTD1 PF18870.1 KDO31874.1 - 0.76 10.0 3.4 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 VWA_2 PF13519.6 KDO31876.1 - 0.00029 21.4 0.0 0.00076 20.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 KDO31876.1 - 0.00032 20.9 14.1 0.00032 20.9 14.1 5.1 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain VWA PF00092.28 KDO31876.1 - 0.016 15.4 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain adh_short PF00106.25 KDO31877.1 - 1.8e-14 53.6 0.0 1.1e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO31877.1 - 2.4e-09 37.1 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KDO31877.1 - 0.0073 16.4 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 KDO31877.1 - 0.017 15.1 0.2 0.037 13.9 0.1 1.7 2 0 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 KDO31877.1 - 0.029 14.6 0.1 0.056 13.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KDO31877.1 - 0.068 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KDO31877.1 - 0.093 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KDO31877.1 - 0.12 12.3 0.2 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.6 KDO31877.1 - 0.13 12.2 0.5 0.28 11.1 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KDO31878.1 - 5.6e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO31878.1 - 7.3e-11 42.1 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KDO31878.1 - 0.00041 20.4 0.1 0.00063 19.8 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KDO31878.1 - 0.0017 18.6 0.1 0.0028 17.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KDO31878.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 KDO31878.1 - 0.12 12.3 0.8 0.2 11.5 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Pkinase PF00069.25 KDO31879.1 - 6.6e-31 107.6 0.0 1.2e-29 103.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO31879.1 - 1.6e-05 24.4 0.0 4.8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 KDO31879.1 - 6.2e-05 22.4 0.0 0.0017 17.7 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO31879.1 - 0.0048 16.9 0.0 0.019 14.9 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO31879.1 - 0.0072 15.2 0.1 0.013 14.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO31879.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec1 PF00995.23 KDO31880.1 - 4.6e-112 376.1 0.0 5.4e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TPP_enzyme_N PF02776.18 KDO31880.1 - 0.0093 15.6 0.2 0.07 12.7 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NOA36 PF06524.12 KDO31882.1 - 0.39 10.0 3.6 0.57 9.5 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein ACC_central PF08326.12 KDO31883.1 - 2.3e-157 525.4 0.0 2.9e-157 525.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KDO31883.1 - 2.2e-152 508.2 0.0 3.2e-152 507.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KDO31883.1 - 2.7e-47 161.0 0.0 6.6e-47 159.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KDO31883.1 - 5.2e-26 91.4 0.0 1.9e-25 89.5 0.0 2.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KDO31883.1 - 2.5e-24 85.5 0.1 4.3e-23 81.5 0.0 2.8 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KDO31883.1 - 5.3e-10 39.0 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KDO31883.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KDO31883.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF1084 PF06454.11 KDO31884.1 - 1.8e-08 34.1 11.4 3.1e-07 30.0 11.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Elicitin PF00964.17 KDO31885.1 - 1.2e-10 41.3 0.1 2.1e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Elicitin DUF1168 PF06658.12 KDO31886.1 - 1.7e-26 92.7 18.0 2.6e-26 92.1 18.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) MRP-L46 PF11788.8 KDO31886.1 - 0.015 16.1 1.8 0.015 16.1 1.8 1.7 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 DUF5401 PF17380.2 KDO31886.1 - 0.057 11.5 15.4 0.068 11.2 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Peptidase_C37 PF05416.12 KDO31886.1 - 1.7 7.1 9.8 2.1 6.8 9.8 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase 14-3-3 PF00244.20 KDO31887.1 - 1e-102 342.3 4.3 1.2e-102 342.2 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 KDO31887.1 - 0.045 14.0 0.2 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 KDO31887.1 - 0.051 13.3 0.4 9.5 6.0 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAM_1 PF00536.30 KDO31888.1 - 1.2e-13 51.3 0.1 3.3e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO31888.1 - 2.8e-11 43.3 1.2 9.6e-11 41.6 0.0 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Response_reg PF00072.24 KDO31888.1 - 3.5e-10 40.1 0.0 9e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Ank_5 PF13857.6 KDO31888.1 - 1.6e-09 37.8 1.4 2.7e-06 27.5 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31888.1 - 2e-07 30.8 0.2 0.00062 20.0 0.1 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KDO31888.1 - 1.2e-06 28.7 1.2 3.4e-06 27.2 0.3 2.4 2 0 0 2 2 1 1 Ankyrin repeat Ank_4 PF13637.6 KDO31888.1 - 5.9e-06 26.7 0.6 1.8e-05 25.2 0.1 2.2 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO31888.1 - 6.7e-06 26.6 0.0 2.2e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) IQ PF00612.27 KDO31888.1 - 0.00015 21.3 38.2 0.033 14.0 2.5 6.7 6 0 0 6 6 6 3 IQ calmodulin-binding motif Abhydrolase_1 PF00561.20 KDO31888.1 - 0.023 14.3 0.0 0.25 10.9 0.0 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold Spectrin PF00435.21 KDO31888.1 - 8.2 7.0 12.9 0.18 12.3 4.9 2.2 2 0 0 2 2 2 0 Spectrin repeat IBR PF01485.21 KDO31890.1 - 0.013 15.7 11.3 0.013 15.7 11.3 3.4 2 1 2 4 4 4 0 IBR domain, a half RING-finger domain Nre_C PF04895.12 KDO31890.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal Nre, C-terminal PX PF00787.24 KDO31891.1 - 6.6e-11 42.2 0.0 2e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 PX domain Cse1 PF08506.10 KDO31892.1 - 3.1e-07 29.6 2.8 2.5e-05 23.3 0.0 3.6 4 0 0 4 4 4 1 Cse1 IBN_N PF03810.19 KDO31892.1 - 2.1e-06 27.6 0.0 6.4e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KDO31892.1 - 0.00011 22.3 0.8 0.0038 17.3 0.1 3.6 3 1 1 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.6 KDO31892.1 - 0.017 15.5 1.3 9.4 6.7 0.0 4.3 3 1 1 4 4 4 0 HEAT repeats RTP1_C1 PF10363.9 KDO31892.1 - 0.041 14.0 1.1 13 6.0 0.0 4.2 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 SUA5 PF03481.13 KDO31892.1 - 0.15 12.6 0.1 0.43 11.2 0.1 1.7 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding SET PF00856.28 KDO31893.1 - 1.5e-15 58.0 0.0 3.2e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KDO31893.1 - 0.018 15.1 2.4 0.018 15.1 2.4 2.6 3 0 0 3 3 3 0 MYND finger UvrB PF12344.8 KDO31893.1 - 0.022 14.6 0.2 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Ultra-violet resistance protein B LRR_4 PF12799.7 KDO31896.1 - 0.0085 16.5 0.1 0.58 10.7 0.1 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO31897.1 - 0.015 15.3 0.0 10 6.4 0.2 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 KDO31897.1 - 0.043 14.3 0.1 0.8 10.2 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) SfsA PF03749.13 KDO31897.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain CENP-B_dimeris PF09026.10 KDO31898.1 - 0.0007 19.9 1.5 0.0017 18.7 1.5 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KDO31898.1 - 1.2 8.8 6.1 1.7 8.3 6.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cnl2_NKP2 PF09447.10 KDO31899.1 - 0.079 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Cnl2/NKP2 family protein V-SNARE_C PF12352.8 KDO31901.1 - 1.1e-07 32.0 0.7 2e-07 31.2 0.7 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF2844 PF11005.8 KDO31901.1 - 0.062 13.3 3.7 3.7 7.6 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2844) PaaB PF06243.11 KDO31901.1 - 0.28 11.4 2.1 0.25 11.6 0.4 1.8 2 0 0 2 2 2 0 Phenylacetic acid degradation B PmbA_TldD PF01523.16 KDO31901.1 - 0.44 10.4 2.8 0.61 9.9 2.8 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF720 PF05302.11 KDO31901.1 - 0.79 9.6 7.4 1.5 8.7 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF720) UCH PF00443.29 KDO31902.1 - 2.2e-33 115.9 0.0 3.4e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO31902.1 - 2.5e-14 53.6 0.0 1.1e-12 48.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ENOD93 PF03386.14 KDO31903.1 - 6e-07 29.3 0.5 1e-06 28.5 0.5 1.3 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 KDO31903.1 - 0.00025 21.2 0.0 0.0007 19.8 0.0 1.8 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CReP_N PF10472.9 KDO31903.1 - 0.13 11.1 0.6 0.17 10.7 0.6 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor HIG_1_N PF04588.13 KDO31904.1 - 1.5e-06 28.3 2.0 1.8e-05 24.9 0.0 2.7 3 0 0 3 3 3 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 KDO31904.1 - 0.021 14.7 0.4 0.049 13.5 0.1 1.7 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein DUF3123 PF11321.8 KDO31904.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) ENOD93 PF03386.14 KDO31905.1 - 6.7e-06 25.9 0.2 1.4e-05 24.8 0.1 1.5 2 0 0 2 2 2 1 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 KDO31905.1 - 0.00087 19.5 1.0 0.0014 18.8 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region H2O2_YaaD PF03883.14 KDO31906.1 - 4.2e-78 262.1 0.0 5.4e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA Pkinase_Tyr PF07714.17 KDO31907.1 - 9.5e-46 156.2 0.0 1.2e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO31907.1 - 7.2e-35 120.6 0.0 1.2e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CTNNBL PF08216.11 KDO31908.1 - 4.3e-29 100.7 0.3 1.4e-28 99.1 0.3 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KDO31908.1 - 3.1e-07 30.2 0.4 0.00013 21.8 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KDO31908.1 - 0.0013 18.7 0.6 0.0049 16.8 0.2 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 KDO31908.1 - 0.015 15.7 3.5 0.18 12.2 0.0 3.6 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 KDO31908.1 - 0.094 13.0 0.3 2.5 8.6 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat SAPS PF04499.15 KDO31909.1 - 0.028 13.2 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UCH PF00443.29 KDO31910.1 - 7e-17 61.8 0.0 1.2e-16 61.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO31910.1 - 0.00053 19.7 0.1 0.0006 19.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.23 KDO31911.1 - 3.7e-79 266.1 0.0 6.3e-79 265.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO31911.1 - 4.3e-16 59.2 0.0 1.5e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding WW PF00397.26 KDO31911.1 - 4e-09 36.4 3.3 9.5e-09 35.2 3.3 1.6 1 0 0 1 1 1 1 WW domain APC_N_CC PF16689.5 KDO31911.1 - 0.07 13.2 0.5 0.21 11.6 0.5 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain K-box PF01486.17 KDO31911.1 - 0.072 13.3 2.0 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 K-box region YabA PF06156.13 KDO31911.1 - 0.41 11.3 4.1 0.65 10.7 0.3 2.6 3 0 0 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 KDO31911.1 - 3.3 8.2 7.9 22 5.6 0.2 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region Adap_comp_sub PF00928.21 KDO31915.1 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KDO31915.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rep-A_N PF04057.12 KDO31916.1 - 5.7e-15 55.2 0.0 6.3e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain BTB_2 PF02214.22 KDO31916.1 - 5.2e-12 45.9 0.0 1.4e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain TPP1 PF10341.9 KDO31916.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD SPRY PF00622.28 KDO31917.1 - 9.4e-07 29.0 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BTB_2 PF02214.22 KDO31917.1 - 0.00019 21.7 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Neuralized PF07177.12 KDO31917.1 - 0.00078 19.5 0.0 0.00095 19.2 0.0 1.3 1 1 0 1 1 1 1 Neuralized CEBP_ZZ PF16366.5 KDO31918.1 - 8.2e-05 22.8 7.1 0.00019 21.6 7.1 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KDO31918.1 - 0.013 15.6 10.2 0.026 14.7 10.2 1.3 1 0 0 1 1 1 0 B-box zinc finger IQ PF00612.27 KDO31918.1 - 0.26 11.2 30.1 1.4 8.9 2.1 4.9 4 0 0 4 4 4 0 IQ calmodulin-binding motif RhaT PF06379.12 KDO31920.1 - 0.02 14.1 0.0 2.2 7.4 0.0 2.0 2 0 0 2 2 2 0 L-rhamnose-proton symport protein (RhaT) Phage_Coat_Gp8 PF05371.12 KDO31920.1 - 0.028 14.2 1.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Phage major coat protein, Gp8 PqqD PF05402.12 KDO31920.1 - 0.03 14.6 0.0 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3953 PF13129.6 KDO31920.1 - 0.05 13.4 0.3 3.1 7.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) ERGIC_N PF13850.6 KDO31920.1 - 0.07 13.5 0.0 13 6.2 0.0 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COX7C PF02935.16 KDO31920.1 - 0.93 9.8 6.1 10 6.4 0.2 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIIc zf-C2H2_10 PF16588.5 KDO31922.1 - 6.3 6.6 17.2 0.82 9.5 1.8 4.0 4 0 0 4 4 4 0 C2H2 zinc-finger VHL PF01847.16 KDO31923.1 - 7.4e-08 32.2 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 VHL beta domain HlyE PF06109.13 KDO31924.1 - 8.4e-34 117.3 2.4 9.4e-27 94.1 0.3 2.0 1 1 1 2 2 2 2 Haemolysin E (HlyE) APG17 PF04108.12 KDO31924.1 - 0.0091 15.2 2.3 0.099 11.7 0.3 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 DUF5424 PF17462.2 KDO31924.1 - 0.12 12.3 0.3 1.6 8.6 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5424) Zmiz1_N PF18028.1 KDO31924.1 - 0.12 12.6 0.0 0.78 10.1 0.0 2.2 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain HlyE PF06109.13 KDO31925.1 - 9.2e-07 28.5 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Haemolysin E (HlyE) Rep_fac_C PF08542.11 KDO31926.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain S4 PF01479.25 KDO31927.1 - 1.3e-11 44.1 0.0 2.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KDO31927.1 - 2e-07 31.8 0.8 3.3e-07 31.1 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain 5_nucleotid PF05761.14 KDO31928.1 - 5.8e-41 140.9 0.0 8.9e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase family RabGAP-TBC PF00566.18 KDO31928.1 - 0.00075 19.2 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YjbR PF04237.13 KDO31928.1 - 0.093 13.3 0.2 0.26 11.9 0.2 1.9 1 0 0 1 1 1 0 YjbR LRAT PF04970.13 KDO31931.1 - 1.3e-08 35.2 0.2 1.1e-07 32.2 0.2 2.2 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Pantoate_ligase PF02569.15 KDO31932.1 - 7.4e-97 323.7 0.0 8.6e-97 323.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase LRR_6 PF13516.6 KDO31933.1 - 5.5e-08 32.3 4.8 0.00034 20.4 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KDO31933.1 - 0.031 14.7 0.6 0.67 10.5 0.0 3.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO31933.1 - 0.057 14.0 0.7 5 8.1 0.1 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat Melittin PF01372.17 KDO31933.1 - 0.33 11.0 2.4 1.6 8.9 0.0 3.3 4 0 0 4 4 4 0 Melittin LRR_8 PF13855.6 KDO31933.1 - 1.1 9.1 4.4 24 4.8 0.2 4.0 4 1 0 4 4 4 0 Leucine rich repeat P21-Arc PF04062.14 KDO31934.1 - 1.6e-67 226.9 0.0 1.8e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit 5_nucleotid PF05761.14 KDO31935.1 - 3.7e-33 115.1 0.0 8.1e-33 114.0 0.0 1.4 1 1 0 1 1 1 1 5' nucleotidase family Hydrolase_like PF13242.6 KDO31935.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like HAD_2 PF13419.6 KDO31935.1 - 0.024 14.7 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase SPC22 PF04573.12 KDO31936.1 - 2.2e-53 180.2 0.4 2.5e-53 180.1 0.4 1.0 1 0 0 1 1 1 1 Signal peptidase subunit SBF2 PF12335.8 KDO31937.1 - 7.3e-06 25.8 2.8 8e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 Myotubularin protein PSCyt1 PF07635.11 KDO31937.1 - 0.039 14.5 0.0 0.15 12.6 0.0 2.1 1 0 0 1 1 1 0 Planctomycete cytochrome C Glyco_hydro_18 PF00704.28 KDO31938.1 - 1.1e-20 74.6 0.2 2e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Peptidase_S8 PF00082.22 KDO31939.1 - 5.7e-45 153.9 4.4 5.7e-45 153.9 4.4 1.6 2 0 0 2 2 2 1 Subtilase family HutP PF09021.11 KDO31939.1 - 0.17 12.2 1.1 0.94 9.8 0.3 2.2 2 0 0 2 2 2 0 HutP LMBR1 PF04791.16 KDO31940.1 - 1e-65 222.6 6.2 1.8e-65 221.8 6.2 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF2933 PF11666.8 KDO31940.1 - 5.4 7.1 8.6 0.31 11.1 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) DSPc PF00782.20 KDO31941.1 - 1.8e-32 111.9 0.0 2.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KDO31941.1 - 4.4e-06 26.9 0.1 6e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KDO31941.1 - 0.00029 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KDO31941.1 - 0.04 14.2 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Glyco_hydro_18 PF00704.28 KDO31942.1 - 2.3e-20 73.6 0.0 3.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.7 KDO31943.1 - 2.5e-36 124.1 19.9 2.2e-13 50.6 0.2 5.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KDO31943.1 - 5.7e-29 99.3 19.9 3e-07 30.6 0.1 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KDO31943.1 - 5.9e-29 100.1 7.9 2.4e-10 40.7 0.4 6.7 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31943.1 - 1.4e-27 92.7 7.2 2.8e-05 24.1 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat TIR_2 PF13676.6 KDO31943.1 - 3.2e-20 72.9 0.0 9.6e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 TIR domain Ank_5 PF13857.6 KDO31943.1 - 1.1e-19 70.2 14.2 6e-08 32.8 0.6 7.1 6 1 1 7 7 7 5 Ankyrin repeats (many copies) TIR PF01582.20 KDO31943.1 - 0.00045 20.1 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 TIR domain WD40 PF00400.32 KDO31944.1 - 3.8e-21 75.0 23.6 0.014 16.2 0.5 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO31944.1 - 3e-08 33.8 5.6 0.0038 17.5 0.1 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO31944.1 - 0.03 13.3 3.3 0.89 8.4 0.0 3.6 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RNase_PH PF01138.21 KDO31945.1 - 8.3e-14 52.2 0.0 1.1e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO31945.1 - 7.3e-11 42.0 0.0 2.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 UPF0047 PF01894.17 KDO31945.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 MIOX PF05153.15 KDO31946.1 - 1.2e-34 120.0 0.0 2.8e-34 118.8 0.0 1.6 1 1 0 1 1 1 1 Myo-inositol oxygenase Fascin PF06268.13 KDO31946.1 - 6.1e-06 26.4 0.0 8.2e-05 22.8 0.0 2.7 2 1 0 2 2 2 1 Fascin domain FRG1 PF06229.12 KDO31946.1 - 0.004 16.9 0.0 0.0094 15.7 0.0 1.6 1 1 0 1 1 1 1 FRG1-like domain FR47 PF08445.10 KDO31946.1 - 0.016 15.2 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 FR47-like protein DUF569 PF04601.13 KDO31946.1 - 0.048 13.3 0.0 0.32 10.7 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF569) Acetyltransf_10 PF13673.7 KDO31946.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO31946.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family cNMP_binding PF00027.29 KDO31947.1 - 1.5e-52 175.6 3.5 1.8e-16 60.0 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Cue1_U7BR PF18499.1 KDO31947.1 - 0.12 12.5 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 IBN_N PF03810.19 KDO31948.1 - 1.2e-08 34.8 0.0 1.3e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KDO31948.1 - 4.1e-07 29.2 0.0 2.1e-05 23.6 0.0 3.2 3 1 0 3 3 3 1 Cse1 P_C10 PF14974.6 KDO31948.1 - 0.019 15.1 0.0 4.9 7.3 0.0 2.8 1 1 1 2 2 2 0 Protein C10 HEAT PF02985.22 KDO31948.1 - 0.042 14.1 3.1 1.7 9.1 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat Xpo1 PF08389.12 KDO31948.1 - 0.1 12.7 1.2 1.3 9.1 0.1 3.4 5 0 0 5 5 5 0 Exportin 1-like protein Vac14_Fab1_bd PF12755.7 KDO31948.1 - 0.17 12.5 0.4 3.9 8.1 0.0 3.4 3 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1487 PF07368.11 KDO31949.1 - 0.041 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) UTP15_C PF09384.10 KDO31950.1 - 0.036 13.7 2.2 0.11 12.2 0.4 2.3 2 0 0 2 2 2 0 UTP15 C terminal Phage_NinH PF06322.11 KDO31950.1 - 0.13 12.2 0.1 23 5.0 0.0 3.2 3 0 0 3 3 3 0 Phage NinH protein Peptidase_M14 PF00246.24 KDO31951.1 - 2.9e-38 132.3 0.0 3.5e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KDO31951.1 - 2.2e-05 23.7 0.0 3.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family RRM_1 PF00076.22 KDO31952.1 - 7.4e-16 57.7 0.0 1.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KDO31952.1 - 1.1e-10 41.4 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KDO31952.1 - 5.7e-06 27.1 0.1 1.5e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 KDO31952.1 - 0.002 18.2 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Proteasome PF00227.26 KDO31954.1 - 5.1e-42 143.5 0.0 5.9e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sad1_UNC PF07738.13 KDO31955.1 - 2.8e-30 105.0 0.1 5.5e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4457 PF14652.6 KDO31955.1 - 0.051 12.8 0.1 3.6 6.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4457) ABC_tran_CTD PF16326.5 KDO31955.1 - 0.14 12.4 0.8 0.53 10.6 0.8 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF5000 PF16391.5 KDO31955.1 - 0.19 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function APH PF01636.23 KDO31956.1 - 1.9e-15 57.5 4.7 2.8e-15 56.9 4.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KDO31956.1 - 0.24 11.0 0.0 0.48 10.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_S10 PF00450.22 KDO31957.1 - 3.7e-95 319.8 0.0 5e-95 319.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase TPD PF14811.6 KDO31958.1 - 1.3e-32 112.5 0.0 2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif ECH_1 PF00378.20 KDO31959.1 - 3.2e-55 187.2 0.0 3.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO31959.1 - 3.7e-16 59.5 0.0 4.2e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PH PF00169.29 KDO31960.1 - 2.1e-12 47.5 0.0 3.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 PH domain GBP PF02263.19 KDO31960.1 - 3.8e-10 39.5 0.0 7.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain PH_11 PF15413.6 KDO31960.1 - 0.0049 17.3 0.1 0.014 15.8 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain AAA_16 PF13191.6 KDO31960.1 - 0.047 14.1 0.1 0.21 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Complex1_LYR PF05347.15 KDO31961.1 - 6.4e-14 51.7 1.3 8e-14 51.4 1.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO31961.1 - 0.00022 21.9 0.5 0.00026 21.7 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KDO31961.1 - 0.019 15.5 0.4 0.021 15.4 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Terminase_GpA PF05876.12 KDO31961.1 - 0.032 12.8 0.0 0.034 12.7 0.0 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) PH PF00169.29 KDO31963.1 - 1.4e-14 54.5 0.0 2.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 PH domain T7SS_ESX_EspC PF10824.8 KDO31963.1 - 0.084 13.4 0.9 36 4.9 0.0 3.6 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm TBP PF00352.21 KDO31964.1 - 1.7e-58 194.5 0.0 1.2e-29 102.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KDO31964.1 - 0.0002 21.4 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4246 PF14033.6 KDO31965.1 - 2.7e-29 102.6 0.0 1.1e-16 61.0 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF4246) EF-hand_1 PF00036.32 KDO31966.1 - 1.5e-09 36.7 0.1 9.9e-05 21.6 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO31966.1 - 8.2e-09 34.7 0.0 0.00055 19.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KDO31966.1 - 4.1e-08 33.5 0.0 1.3e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO31966.1 - 0.00016 21.0 0.4 0.0037 16.7 0.0 2.7 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KDO31966.1 - 0.00037 20.3 0.4 0.04 13.8 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair TPR_MalT PF17874.1 KDO31966.1 - 0.032 13.6 3.0 0.05 13.0 0.4 2.0 1 1 0 2 2 2 0 MalT-like TPR region ArdA PF07275.11 KDO31966.1 - 0.065 13.8 1.0 0.28 11.8 0.7 2.2 1 1 0 1 1 1 0 Antirestriction protein (ArdA) Ank_2 PF12796.7 KDO31967.1 - 1.6e-23 83.1 13.7 8.7e-07 29.5 0.1 4.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31967.1 - 4e-20 71.9 8.8 1.1e-05 25.8 0.6 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31967.1 - 2e-16 58.4 5.6 0.016 15.7 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KDO31967.1 - 1.5e-14 53.9 7.7 7.9e-05 22.9 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ribonuc_2-5A PF06479.12 KDO31967.1 - 1.2e-07 32.0 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Ank PF00023.30 KDO31967.1 - 2.9e-07 30.6 12.0 0.25 11.9 0.0 6.2 6 1 1 7 7 7 3 Ankyrin repeat Pkinase PF00069.25 KDO31967.1 - 0.0049 16.3 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain SAM_PNT PF02198.16 KDO31967.1 - 0.054 13.5 0.5 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF2048 PF09752.9 KDO31968.1 - 3.4e-57 194.1 0.0 4.8e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Hydrolase_4 PF12146.8 KDO31968.1 - 5.6e-07 29.1 0.1 9.3e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO31968.1 - 0.0001 22.1 0.0 0.00039 20.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO31968.1 - 0.00013 22.7 4.5 0.00013 22.7 4.5 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KDO31968.1 - 0.00036 20.3 0.1 0.00055 19.6 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.12 KDO31968.1 - 0.002 17.0 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF915 PF06028.11 KDO31968.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) EF-hand_6 PF13405.6 KDO31970.1 - 5.4e-18 63.3 1.9 6e-06 25.8 0.2 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 KDO31970.1 - 9.3e-17 59.3 4.2 1.8e-06 27.0 0.1 5.0 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 KDO31970.1 - 9.4e-12 45.2 4.1 6.2e-05 23.4 0.1 4.6 4 2 1 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO31970.1 - 6.4e-10 38.1 5.9 0.00034 20.0 0.3 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KDO31970.1 - 1.1e-09 38.0 5.2 0.002 17.9 0.0 4.6 5 2 0 5 5 5 2 EF-hand domain pair Laminin_B PF00052.18 KDO31970.1 - 0.036 14.0 0.0 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 Laminin B (Domain IV) CCDC106 PF15794.5 KDO31970.1 - 0.04 13.6 0.2 0.067 12.9 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 HI0933_like PF03486.14 KDO31971.1 - 5.9e-91 305.2 0.0 6.8e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KDO31971.1 - 3.4e-09 36.8 2.6 1.5e-06 28.1 1.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO31971.1 - 2.9e-07 29.9 6.7 1.4e-05 24.4 3.2 3.0 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KDO31971.1 - 4.3e-06 26.2 1.5 1.3e-05 24.6 0.3 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO31971.1 - 1.6e-05 24.1 2.0 0.05 12.7 0.5 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KDO31971.1 - 3.1e-05 23.3 0.0 7.4e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KDO31971.1 - 4.7e-05 22.6 0.4 0.00012 21.2 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KDO31971.1 - 0.00045 20.4 0.1 0.0011 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KDO31971.1 - 0.00086 18.3 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KDO31971.1 - 0.0022 17.3 0.9 0.0058 15.9 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KDO31971.1 - 0.0058 16.0 0.9 0.0088 15.4 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KDO31971.1 - 0.0093 15.3 0.1 0.63 9.3 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KDO31971.1 - 0.012 14.9 0.8 0.2 10.8 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO31971.1 - 0.013 16.1 0.3 0.15 12.7 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO31971.1 - 0.069 13.1 0.5 0.38 10.7 0.5 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding DUF4250 PF14056.6 KDO31972.1 - 0.32 11.0 1.1 4.5 7.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) PRKG1_interact PF15898.5 KDO31972.1 - 0.33 11.9 11.6 11 7.0 0.0 4.0 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 KDO31972.1 - 5.9 7.2 10.3 0.23 11.7 2.0 2.8 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Smg8_Smg9 PF10220.9 KDO31973.1 - 3.6e-05 22.3 0.4 9.3e-05 21.0 0.1 1.6 2 0 0 2 2 2 1 Smg8_Smg9 RsgA_GTPase PF03193.16 KDO31973.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KDO31973.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KDO31973.1 - 0.0023 18.4 0.0 0.0041 17.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KDO31973.1 - 0.019 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO31973.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KDO31973.1 - 0.05 13.8 0.0 4.8 7.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 KDO31973.1 - 0.21 10.5 0.0 0.42 9.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MPM1 PF17234.2 KDO31974.1 - 0.25 11.6 7.9 0.36 11.1 7.8 1.4 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DNA_topoisoIV PF00521.20 KDO31975.1 - 1.9e-127 425.7 0.0 3.4e-127 424.9 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KDO31975.1 - 1.5e-52 177.2 2.3 1.9e-52 176.9 0.7 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KDO31975.1 - 1.6e-21 76.6 0.6 3.3e-21 75.5 0.6 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KDO31975.1 - 4.6e-12 46.4 0.0 1.6e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KDO31975.1 - 1.9e-07 31.2 0.0 1.4e-06 28.5 0.0 2.6 1 0 0 1 1 1 1 Toprim domain DTHCT PF08070.11 KDO31975.1 - 1.2e-06 29.2 16.1 1.2e-06 29.2 16.1 6.1 3 1 2 5 5 5 1 DTHCT (NUC029) region adh_short PF00106.25 KDO31976.1 - 2.1e-46 157.9 1.2 2.6e-46 157.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO31976.1 - 2.7e-26 92.6 2.0 3.5e-26 92.2 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO31976.1 - 7.5e-11 42.3 0.7 1e-10 41.8 0.7 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KDO31976.1 - 0.00013 21.4 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 KDO31976.1 - 0.0056 17.2 0.2 0.012 16.2 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KDO31976.1 - 0.014 15.8 0.1 0.024 15.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 KDO31976.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KDO31976.1 - 0.055 12.9 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KDO31976.1 - 0.073 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ank_2 PF12796.7 KDO31978.1 - 8.1e-63 209.0 25.5 7.8e-16 58.4 2.3 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO31978.1 - 6e-43 144.7 18.0 8.8e-11 42.1 0.1 7.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO31978.1 - 2.9e-40 131.7 16.9 1.1e-05 25.4 0.1 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KDO31978.1 - 1e-38 130.1 29.8 2.2e-07 31.0 0.1 9.7 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KDO31978.1 - 2.9e-36 123.0 28.3 1.1e-08 35.2 0.4 8.2 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Elicitin PF00964.17 KDO31980.1 - 0.2 11.8 10.7 0.66 10.1 6.9 2.2 1 1 1 2 2 2 0 Elicitin CWC25 PF12542.8 KDO31981.1 - 4.2e-18 66.1 1.4 4.2e-18 66.1 1.4 4.3 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KDO31981.1 - 1.4e-11 44.4 13.6 1.4e-11 44.4 13.6 5.4 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Retinal PF15449.6 KDO31981.1 - 0.01 13.7 51.4 0.017 13.0 51.4 1.4 1 0 0 1 1 1 0 Retinal protein BT1 PF03092.16 KDO31982.1 - 1.3e-17 63.3 4.0 1.3e-17 63.3 4.0 2.2 1 1 1 2 2 2 2 BT1 family PUCC PF03209.15 KDO31982.1 - 4.5e-06 25.9 4.1 1e-05 24.8 4.1 1.6 1 0 0 1 1 1 1 PUCC protein zf-C4H2 PF10146.9 KDO31982.1 - 0.41 10.9 1.0 0.66 10.3 1.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Pkinase PF00069.25 KDO31983.1 - 6e-65 219.2 0.0 7.8e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO31983.1 - 9.8e-34 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KDO31983.1 - 2e-29 101.9 0.8 3e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO31983.1 - 2.7e-29 98.5 10.5 2.7e-07 29.6 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 KDO31983.1 - 2.9e-25 86.6 5.6 2.8e-06 26.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO31983.1 - 6.2e-24 81.8 6.3 3e-06 26.7 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KDO31983.1 - 7e-19 67.4 8.7 1.5e-08 34.3 0.5 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KDO31983.1 - 6.2e-08 32.5 0.0 8.1e-05 22.5 0.0 2.6 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KDO31983.1 - 2.4e-06 27.8 0.0 0.043 14.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO31983.1 - 1.9e-05 24.9 0.0 0.065 13.6 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 KDO31983.1 - 0.00012 21.0 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO31983.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dockerin_1 PF00404.18 KDO31983.1 - 0.00026 21.1 1.6 0.13 12.5 0.2 3.5 2 1 1 3 3 3 1 Dockerin type I domain TerB PF05099.13 KDO31983.1 - 0.0018 18.2 0.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 Tellurite resistance protein TerB APH PF01636.23 KDO31983.1 - 0.0022 18.0 0.9 0.0046 16.9 0.9 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO31983.1 - 0.015 14.6 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like VCBS PF13517.6 KDO31983.1 - 2.2 8.9 4.4 46 4.7 0.8 3.0 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PDEase_I PF00233.19 KDO31984.1 - 4.9e-51 173.8 0.0 8.4e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KDO31984.1 - 2.3e-10 41.2 2.2 0.00039 21.0 0.1 3.2 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 KDO31984.1 - 2.3e-06 28.0 0.4 0.002 18.4 0.0 3.2 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KDO31984.1 - 0.0023 18.3 0.5 1.3 9.4 0.0 3.3 3 0 0 3 3 3 2 GAF domain TPR_11 PF13414.6 KDO31985.1 - 7e-14 51.2 9.5 4.3e-06 26.3 0.0 4.7 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.6 KDO31985.1 - 2.3e-09 37.0 5.7 0.029 14.7 0.0 5.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO31985.1 - 1.4e-08 34.2 8.0 0.038 13.8 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO31985.1 - 1.7e-06 27.7 10.8 1.2 9.4 0.1 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO31985.1 - 0.0026 18.4 10.2 2.4 9.2 0.2 5.1 2 2 3 5 5 5 2 Tetratricopeptide repeat DUF981 PF06168.11 KDO31985.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF981) TPR_6 PF13174.6 KDO31985.1 - 0.13 13.0 3.1 6.8 7.5 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO31985.1 - 0.26 11.6 11.1 3.2 8.2 0.0 6.1 7 1 0 7 7 7 0 Tetratricopeptide repeat tRNA_edit PF04073.15 KDO31986.1 - 6.8e-12 45.6 0.0 8.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Mut7-C PF01927.16 KDO31987.1 - 2.1e-33 115.5 1.0 2.5e-33 115.2 1.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF5615 PF18480.1 KDO31987.1 - 0.012 15.3 0.1 0.024 14.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5615) Rod_C PF10493.9 KDO31987.1 - 0.013 13.9 0.4 0.017 13.6 0.4 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region Cupin_8 PF13621.6 KDO31987.1 - 0.054 13.2 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain eIF-4B PF06273.11 KDO31988.1 - 0.082 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Amidohydro_3 PF07969.11 KDO31989.1 - 2.7e-87 294.2 1.6 3.3e-87 293.9 1.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KDO31989.1 - 2.9e-12 46.6 0.4 4.5e-10 39.4 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family TUDOR_5 PF18359.1 KDO31990.1 - 1.7e-10 40.4 1.9 1.8e-07 30.7 0.3 2.8 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 KDO31990.1 - 1.9e-07 30.8 0.1 4.4e-06 26.4 0.1 2.5 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 KDO31990.1 - 1.1e-06 28.9 0.0 0.00083 19.8 0.0 2.7 2 0 0 2 2 2 2 Agenet domain LBR_tudor PF09465.10 KDO31990.1 - 0.0014 18.4 1.1 0.048 13.5 0.4 2.4 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 KDO31990.1 - 0.0032 17.5 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 KDO31990.1 - 0.0092 16.0 0.0 0.047 13.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 KDO31990.1 - 0.027 14.4 0.1 0.8 9.7 0.0 2.5 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Vac14_Fab1_bd PF12755.7 KDO31990.1 - 0.072 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Tudor_2 PF18104.1 KDO31990.1 - 0.23 11.1 0.3 0.51 10.1 0.3 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain MIF PF01187.18 KDO31991.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) ANAPC4_WD40 PF12894.7 KDO31992.1 - 7.8e-18 64.6 1.0 9.2e-05 22.7 0.0 6.3 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO31992.1 - 2.1e-08 34.6 3.0 0.0069 17.2 0.0 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat IKI3 PF04762.12 KDO31992.1 - 1.2e-05 23.6 0.4 0.11 10.5 0.0 3.2 2 2 1 3 3 3 3 IKI3 family eIF2A PF08662.11 KDO31992.1 - 2.5e-05 24.3 0.2 0.15 11.9 0.0 4.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 KDO31992.1 - 0.00043 19.2 0.0 2.9 6.6 0.0 4.1 4 0 0 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 KDO31992.1 - 0.018 14.9 2.2 5 7.2 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SAM_PNT PF02198.16 KDO31992.1 - 0.085 12.8 0.0 7.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain BK_channel_a PF03493.18 KDO31993.1 - 4.1e-16 59.0 0.0 8.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO31993.1 - 1.7e-12 47.1 1.0 6.6e-12 45.2 0.8 2.2 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KDO31993.1 - 2.7e-08 33.4 4.8 5.7e-08 32.3 4.8 1.5 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO31993.1 - 0.0026 18.0 0.1 0.41 10.9 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain BK_channel_a PF03493.18 KDO31994.1 - 1.1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO31994.1 - 2.6e-10 40.1 3.3 2.6e-10 40.1 3.3 2.4 2 1 1 3 3 3 1 Ion channel Ion_trans PF00520.31 KDO31994.1 - 7.3e-08 31.9 2.5 1.5e-07 30.9 2.5 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO31994.1 - 0.034 14.4 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain IRK PF01007.20 KDO31994.1 - 0.12 12.2 0.5 0.36 10.7 0.5 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Colicin_im PF03857.13 KDO31994.1 - 2 8.3 7.1 0.17 11.8 0.6 2.2 2 0 0 2 2 2 0 Colicin immunity protein Ion_trans_2 PF07885.16 KDO31995.1 - 4.5e-11 42.5 1.2 1.4e-10 41.0 1.2 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 KDO31995.1 - 2.5e-10 40.4 0.0 5.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KDO31995.1 - 5.1e-09 35.7 2.4 1.1e-08 34.7 2.4 1.5 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO31995.1 - 6.8e-05 23.1 0.1 0.00025 21.3 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain LysE PF01810.18 KDO31995.1 - 0.078 12.4 1.0 1.5 8.3 0.3 2.3 2 0 0 2 2 2 0 LysE type translocator Ion_trans_2 PF07885.16 KDO31996.1 - 3.4e-12 46.1 0.5 3.4e-12 46.1 0.5 2.0 2 0 0 2 2 2 1 Ion channel BK_channel_a PF03493.18 KDO31996.1 - 4.9e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KDO31996.1 - 3.8e-10 39.4 5.5 8.4e-10 38.3 5.5 1.6 1 1 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO31996.1 - 0.0002 21.6 0.0 0.001 19.3 0.0 2.1 3 0 0 3 3 3 1 TrkA-N domain ZZ PF00569.17 KDO31997.1 - 2.9e-09 36.6 6.8 4.9e-09 35.9 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KDO31997.1 - 0.00023 21.4 6.0 0.00043 20.5 6.0 1.4 1 0 0 1 1 1 1 C1 domain DZR PF12773.7 KDO31997.1 - 4.2 7.5 8.1 2.7 8.1 5.8 1.9 2 1 0 2 2 2 0 Double zinc ribbon Band_7 PF01145.25 KDO31998.1 - 3e-17 63.2 0.0 1.3e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 SPFH domain / Band 7 family Atg14 PF10186.9 KDO31999.1 - 0.0003 20.0 0.4 0.0003 20.0 0.4 3.4 1 1 2 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 FXMRP1_C_core PF12235.8 KDO31999.1 - 0.0052 17.4 1.3 0.0052 17.4 1.3 3.4 3 2 0 3 3 3 1 Fragile X-related 1 protein core C terminal DUF1759 PF03564.15 KDO31999.1 - 2.1 8.3 8.2 0.91 9.5 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) SAM_1 PF00536.30 KDO32000.1 - 5.1e-11 42.9 0.0 9.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO32000.1 - 8.4e-10 38.6 0.0 2.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 KDO32000.1 - 7.7e-05 22.5 51.4 0.011 15.6 0.4 8.4 9 0 0 9 9 9 5 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KDO32000.1 - 0.00074 19.1 32.0 0.37 10.4 1.9 7.4 7 0 0 7 7 7 2 Ubiquitin-Binding Zinc Finger RNA_pol_3_Rpc31 PF11705.8 KDO32000.1 - 0.0012 19.1 4.3 0.0012 19.1 4.3 2.9 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KDO32000.1 - 0.0086 15.5 15.9 0.01 15.2 13.0 2.0 2 0 0 2 2 2 1 BUD22 RNase_H2_suC PF08615.11 KDO32000.1 - 0.035 14.3 3.2 0.075 13.2 0.6 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SAM_PNT PF02198.16 KDO32000.1 - 0.11 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-U11-48K PF05253.12 KDO32000.1 - 0.17 11.9 9.5 60 3.7 0.0 6.6 7 0 0 7 7 7 0 U11-48K-like CHHC zinc finger PBP1_TM PF14812.6 KDO32000.1 - 0.46 10.9 14.5 6.4 7.2 8.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.11 KDO32000.1 - 0.53 9.9 15.3 1.4 8.5 5.7 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PPP4R2 PF09184.11 KDO32000.1 - 1.7 8.2 15.6 0.017 14.8 3.6 2.9 3 0 0 3 3 3 0 PPP4R2 Pox_RNA_Pol_19 PF05320.12 KDO32000.1 - 1.7 8.6 10.3 2.8 7.9 0.7 2.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4746 PF15928.5 KDO32000.1 - 3.3 7.0 10.6 3.3 7.0 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF1840 PF08895.11 KDO32000.1 - 3.8 7.9 7.3 6.5 7.1 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Cwf_Cwc_15 PF04889.12 KDO32000.1 - 7.5 6.2 17.4 6.4 6.4 10.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EBV-NA3 PF05009.12 KDO32000.1 - 8.6 5.8 10.5 1.7 8.1 3.8 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXT2_N PF08595.11 KDO32000.1 - 9.8 6.2 11.6 4.7 7.2 4.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal p450 PF00067.22 KDO32001.1 - 2.8e-75 253.8 0.0 3.6e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KDO32002.1 - 2.1e-66 224.6 0.0 3e-66 224.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KDO32003.1 - 2.6e-25 89.1 0.0 7e-24 84.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3240 PF11582.8 KDO32003.1 - 0.045 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) p450 PF00067.22 KDO32005.1 - 2.1e-33 115.8 0.0 5.5e-32 111.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KDO32006.1 - 5e-75 253.0 0.0 6.2e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRD PF00874.20 KDO32007.1 - 0.21 11.9 4.1 16 5.8 0.6 3.3 3 0 0 3 3 3 0 PRD domain Methyltr_RsmF_N PF17125.5 KDO32007.1 - 0.94 10.0 4.8 6.5 7.3 0.1 3.7 3 1 1 4 4 4 0 N-terminal domain of 16S rRNA methyltransferase RsmF Mut7-C PF01927.16 KDO32008.1 - 1e-28 100.3 0.4 2.2e-28 99.2 0.4 1.6 1 0 0 1 1 1 1 Mut7-C RNAse domain tRNA_edit PF04073.15 KDO32008.1 - 4.3e-20 72.0 0.2 1.5e-19 70.3 0.2 2.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DNA_pol_A_exo1 PF01612.20 KDO32008.1 - 1.1e-18 67.6 0.1 2.6e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease DUF5615 PF18480.1 KDO32008.1 - 0.006 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) zf-RRN7 PF11781.8 KDO32008.1 - 0.034 13.9 1.6 0.07 12.8 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Transglut_prok PF09017.10 KDO32008.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Microbial transglutaminase BK_channel_a PF03493.18 KDO32009.1 - 1.4e-14 54.1 0.0 2.8e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KDO32009.1 - 4.5e-13 49.0 10.5 8.4e-13 48.1 10.5 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO32009.1 - 1.2e-11 44.4 0.4 1.2e-11 44.4 0.4 1.9 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 KDO32009.1 - 0.00054 20.2 0.1 0.38 11.0 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain PP2C PF00481.21 KDO32010.1 - 1.3e-53 182.3 0.0 1.6e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C CRT-like PF08627.10 KDO32011.1 - 1.5e-11 43.8 3.0 6.3e-06 25.4 2.4 2.7 2 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Cyd_oper_YbgE PF09600.10 KDO32011.1 - 0.056 13.8 2.5 0.12 12.7 2.5 1.5 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Pkinase PF00069.25 KDO32013.1 - 2.8e-47 161.3 0.0 3.6e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32013.1 - 8.6e-25 87.5 0.0 1.2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO32013.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Thioredoxin_8 PF13905.6 KDO32015.1 - 8.3e-24 83.7 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO32015.1 - 3.2e-08 33.5 0.0 0.00024 21.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KDO32015.1 - 2.7e-06 27.8 0.0 4.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KDO32015.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KDO32015.1 - 0.0006 19.7 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KDO32015.1 - 0.15 11.8 0.0 5 6.9 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin DAGAT PF03982.13 KDO32017.1 - 2.4e-75 253.2 0.0 3.3e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MeaB PF03308.16 KDO32018.1 - 1.8e-79 266.5 6.7 9e-79 264.2 6.7 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KDO32018.1 - 2.2e-06 27.6 0.6 0.00046 20.0 0.1 2.4 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 KDO32018.1 - 1.4e-05 24.7 1.7 0.00091 18.9 1.7 2.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KDO32018.1 - 0.00074 18.9 0.6 0.0014 18.0 0.5 1.7 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KDO32018.1 - 0.00093 19.5 0.1 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KDO32018.1 - 0.0012 18.6 0.4 0.0037 17.0 0.0 2.0 1 1 2 3 3 3 1 AAA domain MobB PF03205.14 KDO32018.1 - 0.0016 18.3 0.7 0.14 12.0 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 KDO32018.1 - 0.0025 17.9 0.0 0.0053 16.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KDO32018.1 - 0.0036 17.0 0.1 0.0036 17.0 0.1 1.6 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KDO32018.1 - 0.0045 16.5 0.3 1.3 8.6 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KDO32018.1 - 0.012 15.7 0.2 0.029 14.5 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KDO32018.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KDO32018.1 - 0.02 15.4 0.5 0.04 14.4 0.1 1.7 2 0 0 2 2 1 0 ABC transporter Thymidylate_kin PF02223.17 KDO32018.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.15 KDO32018.1 - 0.023 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 NTPase ParA PF10609.9 KDO32018.1 - 0.027 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KDO32018.1 - 0.028 14.3 0.4 0.087 12.7 0.1 1.9 1 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KDO32018.1 - 0.03 13.5 0.9 0.061 12.5 0.9 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase CLP1_P PF16575.5 KDO32018.1 - 0.034 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 KDO32018.1 - 0.035 13.7 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KDO32018.1 - 0.04 14.5 1.8 0.044 14.3 0.4 1.8 2 0 0 2 2 1 0 AAA domain Arf PF00025.21 KDO32018.1 - 0.044 13.2 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KDO32018.1 - 0.064 13.2 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_10 PF12846.7 KDO32018.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.14 KDO32018.1 - 0.07 12.4 0.1 0.093 11.9 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 KDO32018.1 - 0.071 12.9 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fer4_NifH PF00142.18 KDO32018.1 - 0.08 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.6 KDO32018.1 - 0.087 13.0 0.2 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO32018.1 - 0.088 12.1 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 KDO32018.1 - 0.09 12.5 0.2 0.22 11.3 0.2 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KDO32018.1 - 0.15 12.4 0.1 0.42 11.0 0.1 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KDO32018.1 - 0.16 12.4 0.3 0.28 11.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain SAPIS-gp6 PF16722.5 KDO32018.1 - 0.17 12.4 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Myb_DNA-binding PF00249.31 KDO32019.1 - 8.9e-13 48.2 0.2 1.4e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO32019.1 - 0.00011 22.4 0.2 0.00019 21.6 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO32019.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Myb DNA-binding like tRNA-synt_1 PF00133.22 KDO32020.1 - 4.5e-201 669.2 0.0 5.1e-200 665.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KDO32020.1 - 4.1e-40 137.2 0.0 8.2e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KDO32020.1 - 3.2e-14 52.5 1.5 5.6e-06 25.3 0.3 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KDO32020.1 - 6.4e-13 48.6 0.1 1.4e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KDO32020.1 - 6.3e-07 29.6 1.8 1.7e-06 28.2 1.8 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KDO32020.1 - 0.018 14.4 0.0 4 6.7 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain SRP72 PF08492.12 KDO32020.1 - 0.79 10.2 9.9 2.4 8.7 9.9 1.8 1 0 0 1 1 1 0 SRP72 RNA-binding domain DUF2384 PF09722.10 KDO32021.1 - 0.0095 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Chitin_bind_1 PF00187.19 KDO32022.1 - 1.2e-06 28.9 38.6 2.6e-06 27.8 16.1 3.4 4 1 0 4 4 4 2 Chitin recognition protein Pkinase_Tyr PF07714.17 KDO32024.1 - 1.1e-55 188.7 0.0 1.4e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO32024.1 - 2.3e-53 181.2 0.0 3.1e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO32024.1 - 0.0017 17.2 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO32024.1 - 0.1 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF3149 PF11346.8 KDO32024.1 - 0.13 11.9 1.5 0.28 10.8 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PspB PF06667.12 KDO32024.1 - 0.16 12.0 2.3 0.13 12.3 0.4 1.7 2 0 0 2 2 2 0 Phage shock protein B GAPT PF11770.8 KDO32024.1 - 0.18 11.7 0.8 0.38 10.6 0.8 1.6 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) Pyridoxal_deC PF00282.19 KDO32025.1 - 3.6e-91 305.7 0.0 4.3e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Barwin PF00967.17 KDO32026.1 - 2e-05 24.5 0.1 2.3e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Barwin family PKD_channel PF08016.12 KDO32027.1 - 0.037 12.7 0.1 0.046 12.4 0.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF443 PF04276.12 KDO32027.1 - 0.053 13.3 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) COS PF18568.1 KDO32027.1 - 0.1 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain AAA_12 PF13087.6 KDO32028.1 - 6.3e-42 143.5 0.0 2.7e-41 141.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KDO32028.1 - 4.7e-23 82.3 2.6 1.1e-17 64.7 0.0 3.5 3 1 1 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 KDO32028.1 - 0.018 14.8 1.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ecl1 PF12855.7 KDO32028.1 - 2.8 9.1 8.0 1.1 10.4 3.9 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Pyridoxal_deC PF00282.19 KDO32029.1 - 2.4e-86 289.8 0.0 2.9e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KDO32029.1 - 1.5e-05 24.4 0.1 2.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KDO32029.1 - 0.00058 19.1 0.1 0.6 9.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Spore_YhcN_YlaJ PF09580.10 KDO32029.1 - 0.56 10.3 1.5 0.96 9.5 1.5 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 53-BP1_Tudor PF09038.10 KDO32030.1 - 0.032 14.2 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor LBR_tudor PF09465.10 KDO32030.1 - 0.13 12.1 0.6 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain S-AdoMet_synt_C PF02773.16 KDO32031.1 - 3.9e-65 218.0 0.1 6.9e-65 217.2 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KDO32031.1 - 3.1e-48 163.0 0.0 6e-48 162.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KDO32031.1 - 1.3e-28 99.6 0.2 2.9e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Methyltransf_32 PF13679.6 KDO32032.1 - 5.5e-13 49.2 0.8 3.2e-11 43.5 0.8 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO32032.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO32032.1 - 4.3e-06 27.4 0.0 8.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KDO32032.1 - 6.9e-06 25.8 0.7 0.00042 19.9 0.8 2.5 1 1 1 2 2 2 1 Methyltransferase TRM13 Methyltransf_4 PF02390.17 KDO32032.1 - 4.9e-05 22.9 0.1 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase GidB PF02527.15 KDO32032.1 - 5.4e-05 22.6 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 KDO32032.1 - 0.0028 17.2 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KDO32032.1 - 0.078 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KDO32032.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein ComK PF06338.11 KDO32034.1 - 0.0091 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 ComK protein Zip PF02535.22 KDO32036.1 - 2e-46 158.8 21.5 3.8e-45 154.6 21.5 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter COX7a PF02238.15 KDO32036.1 - 2.3 8.7 6.9 2.7 8.5 0.1 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII IQ PF00612.27 KDO32037.1 - 0.00014 21.4 23.0 0.2 11.5 0.2 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif DUF2838 PF10998.8 KDO32037.1 - 0.14 12.4 0.3 0.36 11.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) zf-MYND PF01753.18 KDO32038.1 - 3.6e-08 33.4 12.2 3.6e-08 33.4 12.2 3.6 3 1 0 3 3 3 2 MYND finger Zeta_toxin PF06414.12 KDO32039.1 - 2.9e-17 62.6 0.0 5.7e-17 61.6 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin ACT PF01842.25 KDO32039.1 - 3e-08 33.3 0.0 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain AAA_33 PF13671.6 KDO32039.1 - 3.9e-05 23.8 0.0 9.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO32039.1 - 0.00038 21.0 0.0 0.0022 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain ACT_4 PF13291.6 KDO32039.1 - 0.00052 20.5 0.0 0.0035 17.9 0.0 2.1 2 0 0 2 2 2 1 ACT domain AAA_16 PF13191.6 KDO32039.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 KDO32039.1 - 0.13 12.1 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Stirrup PF09061.6 KDO32040.1 - 0.15 12.3 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Stirrup Tyrosinase PF00264.20 KDO32041.1 - 2.2e-15 57.6 0.7 1.2e-13 51.8 0.7 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase Haem_oxygenas_2 PF14518.6 KDO32041.1 - 0.15 11.9 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Iron-containing redox enzyme Acetyltransf_14 PF03421.16 KDO32042.1 - 0.078 13.0 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 YopJ Serine/Threonine acetyltransferase BclA_C PF18573.1 KDO32042.1 - 0.1 12.5 0.2 0.49 10.3 0.1 2.1 2 1 0 2 2 2 0 BclA C-terminal domain DUF2861 PF11060.8 KDO32044.1 - 0.12 11.9 0.1 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) BclA_C PF18573.1 KDO32045.1 - 0.00088 19.2 0.7 0.0025 17.7 0.7 1.8 1 0 0 1 1 1 1 BclA C-terminal domain TNF PF00229.18 KDO32045.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family RabGAP-TBC PF00566.18 KDO32047.1 - 9.8e-15 54.8 1.3 9.9e-13 48.2 0.5 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain CTP_transf_3 PF02348.19 KDO32047.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Cytidylyltransferase N2227 PF07942.12 KDO32047.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein HORMA PF02301.18 KDO32048.1 - 9e-49 165.9 0.0 1.3e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Pkinase PF00069.25 KDO32049.1 - 4.5e-52 177.0 0.0 6.7e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32049.1 - 1.2e-48 165.6 0.0 2.2e-48 164.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO32049.1 - 6.8e-10 38.6 1.8 0.00028 20.6 0.6 3.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO32049.1 - 4.3e-09 36.5 7.7 0.00054 20.3 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO32049.1 - 0.00013 20.9 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO32049.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO32049.1 - 0.0052 16.7 0.3 0.068 13.1 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_1 PF00560.33 KDO32049.1 - 0.032 14.8 0.0 42 5.3 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4571 PF15137.6 KDO32049.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) LRR_6 PF13516.6 KDO32049.1 - 0.26 11.4 5.0 32 4.9 0.0 4.4 3 1 1 4 4 4 0 Leucine Rich repeat Cellulase PF00150.18 KDO32052.1 - 1.3e-18 67.4 9.8 1.7e-18 67.0 9.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KDO32053.1 - 1.6e-25 90.1 6.7 2.1e-25 89.7 6.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PHD PF00628.29 KDO32055.1 - 0.32 10.9 5.1 3.6 7.5 4.3 2.7 2 0 0 2 2 2 0 PHD-finger Ank_2 PF12796.7 KDO32056.1 - 1.2e-08 35.4 4.3 0.00016 22.1 0.5 3.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32056.1 - 6.2e-07 29.8 5.1 0.00054 20.5 0.7 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32056.1 - 5.8e-06 26.5 3.3 0.0067 16.7 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO32056.1 - 0.28 11.7 5.6 2.9 8.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KDO32056.1 - 0.41 11.4 12.5 11 7.0 0.0 5.6 6 0 0 6 6 6 0 Ankyrin repeat RNA_pol_Rpb4 PF03874.16 KDO32057.1 - 2e-17 63.7 1.8 3.4e-17 62.9 1.8 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 UPF0020 PF01170.18 KDO32058.1 - 3.7e-10 39.8 0.0 3.9e-05 23.4 0.0 2.5 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KDO32058.1 - 0.0027 17.4 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 KDO32058.1 - 0.026 14.2 0.5 0.096 12.3 0.1 1.9 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase N6-adenineMlase PF10237.9 KDO32058.1 - 0.036 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase N6_Mtase PF02384.16 KDO32058.1 - 0.22 10.8 0.0 0.42 9.8 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase TMF_DNA_bd PF12329.8 KDO32059.1 - 0.019 15.0 12.7 0.43 10.6 0.2 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2911 PF11138.8 KDO32059.1 - 0.13 12.2 1.0 0.29 11.0 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2911) Fez1 PF06818.15 KDO32059.1 - 0.31 11.5 26.0 0.086 13.3 16.2 2.1 1 1 1 2 2 2 0 Fez1 ERM PF00769.19 KDO32059.1 - 0.34 10.7 35.4 1.3 8.8 0.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TFIIA PF03153.13 KDO32059.1 - 0.96 9.4 15.2 1 9.3 15.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAS PF13851.6 KDO32059.1 - 1.4 8.2 27.3 1.6 8.0 15.5 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 KDO32059.1 - 6 7.2 19.6 2 8.7 7.0 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Radial_spoke_3 PF06098.11 KDO32059.1 - 8.5 5.6 22.4 5.6 6.1 19.9 2.0 1 1 0 1 1 1 0 Radial spoke protein 3 Ribonuc_2-5A PF06479.12 KDO32059.1 - 8.6 6.6 8.5 1.1 9.4 1.2 2.6 1 1 2 3 3 3 0 Ribonuclease 2-5A Mpv17_PMP22 PF04117.12 KDO32060.1 - 5.8e-21 74.5 3.8 1.2e-20 73.5 3.8 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Kdo PF06293.14 KDO32061.1 - 9.3e-10 38.2 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KDO32061.1 - 1.7e-09 37.5 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO32061.1 - 2.2e-07 31.1 0.0 0.00021 21.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KDO32061.1 - 4.4e-05 22.9 0.0 5.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KDO32061.1 - 0.00022 20.9 0.1 0.00043 19.9 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KDO32061.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KDO32061.1 - 0.038 13.3 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RB_B PF01857.20 KDO32061.1 - 0.064 13.3 0.4 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain WLM PF08325.10 KDO32063.1 - 3.7e-46 157.6 0.0 4.1e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KDO32063.1 - 0.00044 20.4 0.4 0.00082 19.5 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF45 VPS11_C PF12451.8 KDO32064.1 - 2.5e-13 50.0 0.4 6.6e-13 48.7 0.4 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 KDO32064.1 - 3.5e-10 39.9 2.1 0.00039 20.3 0.0 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KDO32064.1 - 2.1e-06 27.7 8.9 6.3e-06 26.1 8.9 1.9 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KDO32064.1 - 0.0019 18.0 9.5 0.0044 16.8 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO32064.1 - 0.01 15.8 8.4 0.025 14.6 8.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KDO32064.1 - 0.02 15.2 9.5 0.054 13.8 9.5 1.8 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KDO32064.1 - 0.029 14.7 4.5 0.076 13.3 4.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KDO32064.1 - 0.087 12.8 8.7 0.22 11.5 8.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 KDO32064.1 - 1.8 8.6 5.7 1 9.4 3.0 2.0 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_11 PF17123.5 KDO32064.1 - 2.1 8.2 6.8 6.1 6.7 6.8 1.9 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_1 PF14446.6 KDO32064.1 - 2.2 8.3 5.9 6.1 6.9 5.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 KDO32064.1 - 2.9 7.8 8.8 7.6 6.5 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2807 PF10988.8 KDO32065.1 - 5.8e-20 71.8 20.6 2.6e-13 50.2 9.3 3.2 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain DUF4097 PF13349.6 KDO32065.1 - 0.00012 21.5 1.5 0.00012 21.5 1.5 1.7 2 0 0 2 2 2 1 Putative adhesin Glyco_hydro_42M PF08532.10 KDO32065.1 - 0.3 10.5 3.7 15 5.0 0.5 2.9 2 1 1 3 3 3 0 Beta-galactosidase trimerisation domain Mito_fiss_reg PF05308.11 KDO32067.1 - 0.02 15.0 7.8 0.036 14.2 6.4 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator NPV_P10 PF05531.12 KDO32067.1 - 0.021 15.3 14.3 6 7.4 0.2 5.1 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein BAR_3 PF16746.5 KDO32067.1 - 0.026 14.2 2.2 2.1 8.0 0.3 2.9 2 1 0 2 2 2 0 BAR domain of APPL family Baculo_PEP_C PF04513.12 KDO32067.1 - 0.031 14.3 13.0 0.068 13.2 0.3 4.1 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.18 KDO32067.1 - 0.066 13.4 14.2 2.1 8.5 1.9 3.7 2 2 1 3 3 3 0 Cobalamin adenosyltransferase TBCC_N PF16752.5 KDO32067.1 - 0.15 12.5 16.0 0.095 13.2 2.1 4.1 4 1 1 5 5 4 0 Tubulin-specific chaperone C N-terminal domain Tropomyosin_1 PF12718.7 KDO32067.1 - 0.17 12.0 16.9 0.23 11.6 1.3 4.4 3 2 1 4 4 4 0 Tropomyosin like AAA_13 PF13166.6 KDO32067.1 - 0.66 8.5 9.3 6.4 5.3 6.0 2.5 1 1 1 2 2 2 0 AAA domain DUF948 PF06103.11 KDO32067.1 - 1.4 9.2 8.3 2.8 8.3 0.5 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.20 KDO32067.1 - 2.3 7.5 12.7 7.7 5.8 0.5 3.9 2 1 0 3 3 3 0 Tropomyosin Spectrin PF00435.21 KDO32067.1 - 2.6 8.6 22.5 2.2 8.8 3.0 4.6 4 2 1 5 5 4 0 Spectrin repeat NBP1 PF08537.10 KDO32067.1 - 3.4 7.0 7.1 8.8 5.6 6.4 2.0 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF4200 PF13863.6 KDO32067.1 - 4.9 7.6 9.5 10 6.6 2.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) PI3_PI4_kinase PF00454.27 KDO32068.1 - 1.2e-26 94.1 0.0 1.5e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PDZ_6 PF17820.1 KDO32069.1 - 7.9e-10 38.4 0.7 2.7e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KDO32069.1 - 1.6e-09 38.0 0.3 6e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 KDO32069.1 - 0.0017 18.7 0.0 0.077 13.4 0.0 2.7 2 0 0 2 2 2 1 PDZ domain MMR_HSR1 PF01926.23 KDO32069.1 - 0.0027 17.8 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-B_box PF00643.24 KDO32069.1 - 0.017 15.3 7.1 0.17 12.1 1.4 2.6 2 0 0 2 2 2 0 B-box zinc finger ArfGap PF01412.18 KDO32069.1 - 0.049 13.7 1.4 0.14 12.2 1.4 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf PDZ_2 PF13180.6 KDO32069.1 - 0.06 13.7 0.7 8.7 6.8 0.0 2.8 2 0 0 2 2 2 0 PDZ domain Cytochrom_c3_2 PF14537.6 KDO32069.1 - 0.13 12.8 4.8 0.064 13.7 1.9 2.0 2 0 0 2 2 2 0 Cytochrome c3 Stanniocalcin PF03298.13 KDO32071.1 - 2.7e-05 23.6 0.3 3.3e-05 23.3 0.3 1.1 1 0 0 1 1 1 1 Stanniocalcin family PX PF00787.24 KDO32072.1 - 2.6e-18 66.0 0.0 4.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 PX domain LAMTOR PF15454.6 KDO32072.1 - 0.0043 17.6 1.0 0.0095 16.5 1.0 1.6 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Abhydrolase_4 PF08386.10 KDO32073.1 - 5e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KDO32073.1 - 0.0001 21.7 0.0 0.58 9.4 0.0 3.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO32073.1 - 0.0004 20.1 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold AA_permease_2 PF13520.6 KDO32074.1 - 2.6e-20 72.6 27.2 3.4e-20 72.3 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO32074.1 - 2.2e-14 53.0 20.4 2.9e-10 39.3 1.8 2.2 2 0 0 2 2 2 2 Amino acid permease U-box PF04564.15 KDO32075.1 - 7.7e-19 67.7 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32075.1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF2576 PF10845.8 KDO32075.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) zf-NOSIP PF15906.5 KDO32075.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 KDO32075.1 - 0.24 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KDO32076.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 PX domain Glft2_N PF17994.1 KDO32076.1 - 0.03 14.2 0.2 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Galactofuranosyltransferase 2 N-terminal LmjF365940-deam PF14421.6 KDO32077.1 - 2.2e-56 190.5 0.0 3.1e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Med3 PF11593.8 KDO32077.1 - 0.14 11.3 2.1 0.2 10.8 2.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF155 PF02582.14 KDO32078.1 - 8.1e-52 175.9 0.5 1.3e-51 175.2 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 gerPA PF10676.9 KDO32078.1 - 0.067 13.5 0.4 0.15 12.4 0.4 1.5 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF GCD14 PF08704.10 KDO32080.1 - 2.9e-63 213.9 0.1 4.8e-62 209.8 0.1 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KDO32080.1 - 3.9e-10 39.7 0.0 8.7e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO32080.1 - 2.8e-07 31.2 0.0 5.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO32080.1 - 1.5e-06 28.7 0.0 7.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KDO32080.1 - 8.9e-06 26.7 0.0 3.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO32080.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14_N PF14801.6 KDO32080.1 - 0.0002 21.1 0.1 0.00062 19.6 0.1 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltr_RsmB-F PF01189.17 KDO32080.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 KDO32080.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KDO32080.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KDO32080.1 - 0.017 15.9 0.0 0.041 14.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KDO32080.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Fibrillarin PF01269.17 KDO32080.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_3 PF01596.17 KDO32080.1 - 0.21 10.7 0.0 0.47 9.6 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Ank_2 PF12796.7 KDO32081.1 - 6.3e-33 113.2 4.9 2.8e-16 59.9 0.4 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32081.1 - 1.6e-31 108.3 3.8 1.5e-08 35.0 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO32081.1 - 9.7e-26 89.0 7.1 0.00034 20.9 0.0 7.2 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KDO32081.1 - 3e-24 84.7 7.5 2e-06 27.9 0.1 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32081.1 - 4.7e-23 78.8 1.7 0.0045 17.4 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Peptidase_S41 PF03572.18 KDO32082.1 - 7.3e-06 25.6 0.0 1.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 DHHC PF01529.20 KDO32083.1 - 2.2e-34 118.4 2.1 2.2e-34 118.4 2.1 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.12 KDO32083.1 - 0.00022 21.1 0.1 0.00022 21.1 0.1 2.1 2 0 0 2 2 2 1 PIG-P DUF3054 PF11255.8 KDO32083.1 - 0.094 13.2 4.6 2.1 8.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) G0-G1_switch_2 PF15103.6 KDO32083.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 Snf7 PF03357.21 KDO32084.1 - 1e-29 103.3 9.7 1.4e-29 102.9 9.7 1.2 1 0 0 1 1 1 1 Snf7 Dcc1 PF09724.9 KDO32084.1 - 0.0012 18.3 4.0 0.023 14.0 0.2 2.0 1 1 1 2 2 2 2 Sister chromatid cohesion protein Dcc1 UPF0240 PF06784.11 KDO32084.1 - 0.57 10.2 7.3 0.71 9.9 5.3 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) YlqD PF11068.8 KDO32084.1 - 1.6 9.1 10.6 2.3 8.6 10.2 1.5 1 1 0 1 1 1 0 YlqD protein Atg14 PF10186.9 KDO32084.1 - 1.9 7.5 10.1 2.5 7.1 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KDO32084.1 - 7 6.4 13.0 0.95 9.3 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ParBc PF02195.18 KDO32085.1 - 6.2e-06 26.4 0.0 9.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain DUF21 PF01595.20 KDO32086.1 - 2.9e-30 105.3 2.9 5e-30 104.5 2.9 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO32086.1 - 1.7e-06 28.4 1.4 0.0097 16.3 0.1 3.3 2 1 0 2 2 2 2 CBS domain DUF21 PF01595.20 KDO32087.1 - 1.4e-31 109.6 4.2 2.1e-31 109.0 4.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KDO32087.1 - 0.0019 18.6 1.8 0.3 11.6 0.1 3.2 2 1 0 2 2 2 2 CBS domain CoA_binding_2 PF13380.6 KDO32087.1 - 0.013 16.0 0.1 0.05 14.1 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Trypsin_2 PF13365.6 KDO32088.1 - 3.1e-11 44.4 0.1 1e-10 42.7 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO32088.1 - 0.0013 18.6 3.2 0.0069 16.2 0.2 2.3 1 1 1 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 KDO32088.1 - 0.19 10.4 0.5 1.5 7.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 POP1 PF06978.11 KDO32089.1 - 0.065 13.2 0.7 0.095 12.7 0.1 1.5 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 p450 PF00067.22 KDO32090.1 - 1.5e-76 258.1 0.0 1.8e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2508 PF10704.9 KDO32090.1 - 0.17 12.0 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) DUF726 PF05277.12 KDO32091.1 - 2.5e-21 76.0 0.0 4.8e-16 58.6 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Lipase_3 PF01764.25 KDO32091.1 - 9.2e-06 25.6 0.1 2.4e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.12 KDO32091.1 - 7.7e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Aconitase_B_N PF11791.8 KDO32091.1 - 0.0021 18.1 0.2 0.007 16.4 0.1 1.8 2 0 0 2 2 2 1 Aconitate B N-terminal domain Abhydrolase_6 PF12697.7 KDO32091.1 - 0.0095 16.6 3.6 0.0095 16.6 3.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO32091.1 - 0.027 13.7 0.2 0.1 11.9 0.1 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KDO32091.1 - 0.028 13.9 0.1 0.057 12.9 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 KDO32091.1 - 0.091 12.5 0.2 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KDO32091.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Methyltransf_33 PF10017.9 KDO32092.1 - 2.8e-92 309.2 0.2 3.4e-92 308.9 0.2 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Peptidase_M16 PF00675.20 KDO32092.1 - 0.038 14.0 0.5 11 5.9 0.0 3.1 2 1 1 3 3 3 0 Insulinase (Peptidase family M16) DUF3836 PF12930.7 KDO32092.1 - 0.092 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF3836) 3Beta_HSD PF01073.19 KDO32095.1 - 9.7e-39 133.0 0.0 1.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KDO32095.1 - 6e-23 81.6 0.0 8e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO32095.1 - 3.4e-14 53.1 0.0 4.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KDO32095.1 - 6.6e-13 48.4 0.0 1.8e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KDO32095.1 - 2.7e-12 46.7 0.0 6.1e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KDO32095.1 - 6.3e-09 35.4 0.1 1.4e-08 34.2 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO32095.1 - 2.7e-08 33.3 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KDO32095.1 - 0.00034 20.6 0.7 0.0093 15.9 0.7 2.7 2 1 0 2 2 2 1 KR domain NmrA PF05368.13 KDO32095.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KDO32095.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 KDO32095.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Anoctamin PF04547.12 KDO32097.1 - 1.4e-108 363.6 7.3 1.7e-108 363.4 7.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO32097.1 - 7.7e-07 29.1 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 KDO32097.1 - 6.4 5.4 10.9 2.5 6.8 0.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) zf-TAZ PF02135.16 KDO32098.1 - 0.24 11.9 28.6 1.2 9.6 3.5 2.9 2 0 0 2 2 2 0 TAZ zinc finger RNA_pol_Rpb1_R PF05001.13 KDO32101.1 - 0.006 16.9 19.0 0.34 11.3 2.9 2.9 2 0 0 2 2 2 2 RNA polymerase Rpb1 C-terminal repeat Glyco_hydro_6 PF01341.17 KDO32102.1 - 2.1e-45 155.8 1.7 3.6e-45 155.0 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PX PF00787.24 KDO32103.1 - 1.2e-11 44.6 0.6 2.3e-11 43.6 0.6 1.5 1 0 0 1 1 1 1 PX domain GOLD_2 PF13897.6 KDO32103.1 - 0.00011 22.7 0.0 0.2 12.2 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking Anoctamin PF04547.12 KDO32105.1 - 9.2e-108 361.0 12.2 1.1e-107 360.7 12.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO32105.1 - 3.8e-06 26.8 0.0 6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF1129 PF06570.11 KDO32105.1 - 0.37 10.2 2.9 0.4 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4083 PF13314.6 KDO32105.1 - 5.2 7.1 11.0 0.46 10.5 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) TssO PF17561.2 KDO32105.1 - 7.7 6.6 8.3 19 5.3 1.0 2.8 3 0 0 3 3 3 0 Type VI secretion system, TssO U-box PF04564.15 KDO32106.1 - 2.2e-33 114.3 0.0 3.2e-18 65.7 0.0 2.7 2 0 0 2 2 2 2 U-box domain zf-Nse PF11789.8 KDO32106.1 - 3.3e-09 36.4 0.0 0.00016 21.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32106.1 - 3.8e-06 26.9 0.0 0.058 13.5 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KDO32106.1 - 0.021 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO32106.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KDO32106.1 - 0.1 12.0 0.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger U-box PF04564.15 KDO32107.1 - 4.5e-17 62.0 0.0 8.7e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 KDO32107.1 - 0.00075 19.5 0.2 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 KDO32107.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32107.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-rbx1 PF12678.7 KDO32107.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain U-box PF04564.15 KDO32108.1 - 1e-14 54.4 0.0 2.2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32108.1 - 4.9e-05 23.1 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KDO32110.1 - 1.2e-16 60.7 0.0 2.7e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32110.1 - 5.6e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32110.1 - 0.0088 16.2 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KDO32110.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger U-box PF04564.15 KDO32111.1 - 0.0025 18.0 0.0 0.0084 16.3 0.0 2.0 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32111.1 - 0.18 11.7 0.0 0.69 9.8 0.0 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KDO32112.1 - 1.3e-16 60.5 0.0 3.6e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32112.1 - 5.4e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32112.1 - 0.0028 17.8 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KDO32113.1 - 5.5e-17 61.7 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32113.1 - 1.2e-05 25.0 0.1 5.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32113.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KDO32113.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger LRR_4 PF12799.7 KDO32114.1 - 0.45 11.0 2.7 2.1 8.9 0.5 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) U-box PF04564.15 KDO32115.1 - 3e-14 52.9 0.1 4.3e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32115.1 - 0.00021 21.0 0.1 0.00057 19.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32115.1 - 0.0049 17.0 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KDO32115.1 - 0.03 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger U-box PF04564.15 KDO32116.1 - 2.1e-17 63.0 0.0 5.6e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32116.1 - 3.6e-05 23.5 0.0 9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32116.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Smim3 PF17307.2 KDO32116.1 - 0.024 14.1 0.2 0.064 12.8 0.2 1.7 1 0 0 1 1 1 0 Small integral membrane protein 3 zf-RING_UBOX PF13445.6 KDO32116.1 - 0.025 14.6 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger U-box PF04564.15 KDO32118.1 - 7.7e-19 67.6 0.0 1.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KDO32118.1 - 0.0079 16.3 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein SSF PF00474.17 KDO32119.1 - 1e-24 87.2 20.8 1.9e-24 86.3 20.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family COX16 PF14138.6 KDO32120.1 - 4.4e-14 52.8 0.8 2.6e-13 50.3 0.8 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF4516 PF14990.6 KDO32121.1 - 3.6e-14 52.2 0.1 4.2e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) CobT PF06213.12 KDO32123.1 - 0.85 8.9 4.2 7.5 5.9 0.2 2.7 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT SET PF00856.28 KDO32124.1 - 3.7e-14 53.5 0.1 4.1e-13 50.1 0.1 2.3 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KDO32124.1 - 2e-06 27.7 3.4 7e-06 26.0 3.4 2.0 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 KDO32124.1 - 3.3e-05 23.7 11.2 3.3e-05 23.7 11.2 2.5 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KDO32124.1 - 0.28 10.8 9.8 0.022 14.3 4.2 2.1 2 0 0 2 2 2 0 PHD-finger AT_hook PF02178.19 KDO32124.1 - 1.2 9.2 14.1 1.9 8.6 0.3 3.7 3 0 0 3 3 3 0 AT hook motif FYVE_2 PF02318.16 KDO32124.1 - 2.3 8.4 7.1 0.086 13.1 0.7 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger TPX2_importin PF12214.8 KDO32126.1 - 0.0028 17.9 23.1 0.0031 17.7 4.1 3.7 3 1 1 4 4 4 3 Cell cycle regulated microtubule associated protein Kre28 PF17097.5 KDO32127.1 - 0.3 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component TLD PF07534.16 KDO32128.1 - 1.2e-31 109.8 0.0 2.1e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 TLD RhoGAP PF00620.27 KDO32128.1 - 3e-18 66.1 0.0 6.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RUN PF02759.19 KDO32128.1 - 1.1e-11 44.9 0.1 2.8e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 RUN domain ELMO_CED12 PF04727.13 KDO32128.1 - 3.1e-06 27.4 0.1 7.3e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family MT-A70 PF05063.14 KDO32130.1 - 1.7e-46 158.3 0.0 2.3e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 MT-A70 DUF2330 PF10092.9 KDO32130.1 - 0.048 12.7 0.4 0.075 12.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) RAI1 PF08652.11 KDO32131.1 - 1e-17 64.1 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease GRP PF07172.11 KDO32132.1 - 4e-05 24.2 17.2 4e-05 24.2 17.2 2.1 1 1 1 2 2 2 1 Glycine rich protein family Anoctamin PF04547.12 KDO32133.1 - 1.4e-173 577.8 33.4 6.8e-110 368.0 15.3 2.2 2 0 0 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO32133.1 - 2.1e-10 40.7 0.0 0.04 13.6 0.0 4.4 4 0 0 4 4 4 4 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Claudin_2 PF13903.6 KDO32133.1 - 0.0095 15.7 0.1 0.0095 15.7 0.1 3.5 4 1 0 4 4 4 1 PMP-22/EMP/MP20/Claudin tight junction U-box PF04564.15 KDO32134.1 - 5.4e-17 61.7 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32134.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KDO32134.1 - 0.0091 16.1 0.0 0.028 14.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein CCDC85 PF10226.9 KDO32135.1 - 0.0033 17.1 13.3 0.021 14.5 1.5 3.2 1 1 1 2 2 2 2 CCDC85 family XhlA PF10779.9 KDO32135.1 - 0.58 10.4 8.4 1.3 9.3 0.1 3.6 3 0 0 3 3 3 0 Haemolysin XhlA HAP1_N PF04849.13 KDO32135.1 - 0.72 9.0 29.0 0.45 9.7 24.7 2.6 2 1 0 2 2 2 0 HAP1 N-terminal conserved region BLOC1_2 PF10046.9 KDO32135.1 - 1.8 8.9 13.8 4.2 7.7 1.0 4.0 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CemA PF03040.14 KDO32135.1 - 5.2 6.9 8.4 0.27 11.1 2.0 2.0 2 0 0 2 2 2 0 CemA family DUF724 PF05266.14 KDO32135.1 - 5.3 6.8 19.6 0.3 10.9 3.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ODV-E18 PF10717.9 KDO32136.1 - 0.041 13.7 0.2 0.085 12.7 0.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EF-hand_13 PF17958.1 KDO32137.1 - 2.9e-33 113.5 0.1 6.7e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KDO32137.1 - 5.9e-17 61.9 5.1 1.3e-12 48.0 1.5 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO32137.1 - 0.00033 20.4 0.7 5.5 7.2 0.0 4.6 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 KDO32137.1 - 0.0025 17.2 4.1 1.4 8.7 0.0 4.5 5 0 0 5 5 5 2 EF hand DUF4187 PF13821.6 KDO32137.1 - 0.071 12.9 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Sin3_corepress PF08295.12 KDO32138.1 - 0.0067 16.5 0.1 0.007 16.4 0.1 1.1 1 0 0 1 1 1 1 Sin3 family co-repressor CHCH PF06747.13 KDO32138.1 - 0.009 16.1 3.5 0.013 15.6 3.5 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KDO32138.1 - 0.011 15.4 3.3 0.014 15.1 3.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MTCP1 PF08991.10 KDO32138.1 - 0.017 15.3 5.5 0.025 14.8 5.5 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Anoctamin PF04547.12 KDO32139.1 - 5.6e-120 401.2 10.4 1.1e-59 202.5 0.0 3.2 2 1 0 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO32139.1 - 5.7e-13 49.1 0.0 2.4e-08 34.0 0.0 3.1 3 0 0 3 3 3 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF4728 PF15860.5 KDO32139.1 - 3.4 8.4 6.5 17 6.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) Anoctamin PF04547.12 KDO32140.1 - 8e-104 348.0 15.9 1.1e-103 347.6 15.9 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO32140.1 - 2.4e-06 27.4 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin TGBp3 PF02495.17 KDO32140.1 - 0.069 12.8 1.6 0.28 10.9 1.6 2.1 1 0 0 1 1 1 0 Triple gene block 3 DUF2207 PF09972.9 KDO32140.1 - 0.15 10.8 4.4 0.28 9.9 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Post_transc_reg PF13797.6 KDO32140.1 - 0.52 10.2 2.0 4.8 7.1 0.3 2.5 2 0 0 2 2 2 0 Post-transcriptional regulator PDZ PF00595.24 KDO32141.1 - 4.2e-07 30.2 0.0 0.29 11.5 0.0 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KDO32141.1 - 5e-05 23.1 0.0 4.3 7.3 0.0 3.4 3 0 0 3 3 3 3 PDZ domain FWWh PF14922.6 KDO32142.1 - 1.3e-06 28.4 0.4 6.4e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function Anoctamin PF04547.12 KDO32143.1 - 2.3e-110 369.5 20.3 2.7e-110 369.3 20.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO32143.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin ASC PF00858.24 KDO32143.1 - 0.065 12.2 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF2207 PF09972.9 KDO32143.1 - 5.1 5.7 10.3 0.15 10.8 0.1 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF373 PF04123.13 KDO32143.1 - 8.9 5.6 11.6 0.45 9.9 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF373) Cep57_MT_bd PF06657.13 KDO32144.1 - 0.35 11.4 14.0 2.4 8.7 0.5 4.3 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Cnn_1N PF07989.11 KDO32144.1 - 0.37 11.0 10.8 3.5 7.8 0.2 4.2 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 KDO32144.1 - 1.6 9.1 17.4 11 6.4 2.1 3.0 1 1 1 2 2 2 0 Fez1 Swi5 PF07061.11 KDO32144.1 - 3.9 7.6 10.0 6.6 6.9 0.2 3.7 3 0 0 3 3 3 0 Swi5 DUF4375 PF14300.6 KDO32144.1 - 4 7.7 5.9 3.6 7.9 3.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) TMF_DNA_bd PF12329.8 KDO32144.1 - 7.6 6.6 13.4 3 7.9 0.1 3.7 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding PP2C PF00481.21 KDO32145.1 - 9.3e-43 146.7 0.0 1.3e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO32145.1 - 0.0048 16.6 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KDO32146.1 - 6.9e-41 140.6 0.0 9.8e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO32146.1 - 9.3e-06 25.4 0.0 1.7e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO32146.1 - 0.0024 17.8 0.8 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) bZIP_2 PF07716.15 KDO32147.1 - 8.9 6.5 7.6 0.55 10.4 2.5 1.7 2 0 0 2 2 2 0 Basic region leucine zipper CREPT PF16566.5 KDO32148.1 - 0.002 18.3 1.2 0.0032 17.6 1.2 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour HR1 PF02185.16 KDO32148.1 - 0.0087 16.2 5.6 0.0087 16.2 5.6 2.0 2 0 0 2 2 2 1 Hr1 repeat MPS2 PF17060.5 KDO32148.1 - 0.39 9.9 2.9 0.58 9.4 2.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 ECM11 PF15463.6 KDO32148.1 - 0.62 10.7 5.4 1.7 9.2 5.4 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 DUF4094 PF13334.6 KDO32149.1 - 0.0097 16.3 0.8 0.08 13.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) HR1 PF02185.16 KDO32149.1 - 1.9 8.6 7.9 0.14 12.3 1.5 2.1 2 0 0 2 2 2 0 Hr1 repeat HR1 PF02185.16 KDO32150.1 - 0.0051 16.9 3.2 0.0051 16.9 3.2 1.9 2 0 0 2 2 2 1 Hr1 repeat Phage_BR0599 PF09356.10 KDO32151.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 EF-hand_6 PF13405.6 KDO32152.1 - 7.2e-05 22.4 0.0 0.00026 20.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KDO32152.1 - 0.00035 21.0 0.0 0.0013 19.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO32152.1 - 0.00043 19.6 0.0 0.00099 18.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KDO32152.1 - 0.0081 16.0 0.1 0.045 13.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair UPF0052 PF01933.18 KDO32153.1 - 5.3e-86 288.5 0.4 7.9e-86 287.9 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD_2 PF13419.6 KDO32153.1 - 7.6e-10 39.1 0.0 2.1e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO32153.1 - 2.5e-07 31.2 0.1 4.8e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO32153.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_4 PF12146.8 KDO32153.1 - 0.14 11.4 0.0 9.5 5.4 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PGK PF00162.19 KDO32153.1 - 0.17 10.8 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoglycerate kinase DUF1803 PF08820.10 KDO32153.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) UQ_con PF00179.26 KDO32154.1 - 3e-53 179.3 0.0 3.4e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KDO32154.1 - 0.034 14.4 0.1 0.053 13.8 0.1 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KDO32154.1 - 0.037 13.7 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B CDC14 PF08045.11 KDO32155.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Cell division control protein 14, SIN component RTP1_C1 PF10363.9 KDO32155.1 - 0.11 12.7 0.8 13 6.0 0.1 2.9 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase PF00069.25 KDO32156.1 - 7.3e-52 176.3 0.0 9.2e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32156.1 - 1.4e-26 93.3 0.0 4.8e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO32156.1 - 8.1e-05 22.6 1.0 0.0097 15.8 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO32156.1 - 0.00015 20.9 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KDO32156.1 - 0.0036 16.9 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KDO32156.1 - 0.005 15.7 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO32156.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Integrase_DNA PF02920.15 KDO32156.1 - 0.071 12.8 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase zf-RING_2 PF13639.6 KDO32158.1 - 4.3e-13 49.4 8.1 4.3e-13 49.4 8.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KDO32158.1 - 1.1e-08 34.6 6.3 2.5e-08 33.5 6.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO32158.1 - 6.1e-08 32.8 5.7 6.1e-08 32.8 5.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO32158.1 - 4.4e-07 29.6 7.8 9.6e-07 28.5 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO32158.1 - 7.9e-07 29.0 4.7 2.1e-06 27.7 4.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO32158.1 - 8.7e-07 28.9 9.4 2.1e-06 27.7 5.9 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO32158.1 - 2e-06 27.6 5.5 3.7e-06 26.7 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO32158.1 - 3.2e-06 26.9 9.4 5.6e-06 26.1 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO32158.1 - 3.9e-05 23.5 7.5 7.4e-05 22.6 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KDO32158.1 - 5.6e-05 22.7 4.7 5.6e-05 22.7 4.7 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KDO32158.1 - 0.00011 22.2 10.3 0.00085 19.4 10.3 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 KDO32158.1 - 0.00027 20.7 2.4 0.0005 19.8 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 KDO32158.1 - 0.0009 19.3 9.4 0.002 18.2 9.4 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 KDO32158.1 - 0.005 17.1 2.8 0.011 16.0 2.8 1.5 1 0 0 1 1 1 1 RING-like domain Prok-RING_4 PF14447.6 KDO32158.1 - 0.0057 16.5 6.2 0.011 15.6 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF4268 PF14088.6 KDO32158.1 - 0.034 14.0 0.9 0.076 12.9 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) PHD PF00628.29 KDO32158.1 - 0.051 13.5 7.4 0.11 12.5 7.4 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KDO32158.1 - 0.24 11.5 5.0 0.47 10.6 5.0 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KDO32158.1 - 0.31 10.9 8.0 0.57 10.0 8.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF5345 PF17280.2 KDO32158.1 - 2 8.5 6.1 0.32 11.0 2.0 1.8 2 0 0 2 2 1 0 Family of unknown function (DUF5345) Pkinase PF00069.25 KDO32161.1 - 1.7e-65 221.0 0.0 2.1e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32161.1 - 1.3e-28 100.0 0.0 2.9e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KDO32161.1 - 0.0035 16.7 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO32161.1 - 0.011 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KDO32161.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Retrotran_gag_2 PF14223.6 KDO32164.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HECT PF00632.25 KDO32165.1 - 6.9e-92 308.2 0.0 1.1e-91 307.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CD36 PF01130.21 KDO32166.1 - 1.5e-35 122.7 2.3 5e-19 68.2 0.4 3.4 2 1 1 3 3 3 3 CD36 family DUF3742 PF12553.8 KDO32166.1 - 0.028 14.5 0.2 0.092 12.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) START PF01852.19 KDO32167.1 - 8.1e-21 74.4 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 START domain Methyltransf_13 PF08421.11 KDO32167.1 - 0.054 13.7 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative zinc binding domain peroxidase PF00141.23 KDO32168.1 - 1.5e-42 145.9 0.0 2.4e-42 145.2 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Glyco_tranf_2_3 PF13641.6 KDO32168.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 peroxidase PF00141.23 KDO32169.1 - 5.5e-32 111.3 0.0 3.1e-24 86.0 0.0 2.2 1 1 1 2 2 2 2 Peroxidase DENN PF02141.21 KDO32170.1 - 8.1e-34 117.2 2.4 3.2e-33 115.3 2.5 1.9 1 1 1 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 KDO32170.1 - 3.6e-05 23.7 0.0 9.1e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 dDENN domain RGS PF00615.19 KDO32170.1 - 0.0018 18.6 10.7 0.028 14.7 0.1 2.9 3 0 0 3 3 3 2 Regulator of G protein signaling domain IZUMO PF15005.6 KDO32171.1 - 0.013 16.0 0.0 0.035 14.6 0.0 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated HAUS6_N PF14661.6 KDO32171.1 - 0.015 14.9 0.4 0.025 14.2 0.4 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CCDC144C PF14915.6 KDO32171.1 - 0.036 13.2 1.2 0.072 12.2 1.2 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DDE_Tnp_ISL3 PF01610.17 KDO32171.1 - 0.042 13.6 0.7 0.13 12.0 0.7 1.7 1 1 0 1 1 1 0 Transposase ERM PF00769.19 KDO32171.1 - 0.056 13.2 3.8 0.092 12.6 3.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SET PF00856.28 KDO32172.1 - 0.0036 17.7 0.0 0.0052 17.2 0.0 1.2 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KDO32173.1 - 1.4e-18 67.9 2.8 1.8e-18 67.4 1.3 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Myosin_head PF00063.21 KDO32174.1 - 3e-212 706.5 0.0 2.2e-191 637.6 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 KDO32174.1 - 6.7e-09 34.8 41.0 0.0026 17.4 1.8 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif PDZ PF00595.24 KDO32174.1 - 1.4e-08 35.0 0.2 0.79 10.1 0.0 3.8 3 1 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KDO32174.1 - 6.5e-07 29.1 0.0 0.3 10.9 0.0 3.8 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 KDO32174.1 - 2.7e-05 24.1 0.0 0.14 12.2 0.0 3.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 KDO32174.1 - 0.012 16.0 1.0 8.8 6.7 0.1 3.5 3 0 0 3 3 3 0 PDZ domain T2SSE PF00437.20 KDO32174.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KDO32174.1 - 0.028 14.8 5.7 0.065 13.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.26 KDO32174.1 - 0.042 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 KDO32174.1 - 0.048 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO32174.1 - 0.092 13.1 2.3 0.096 13.0 0.3 2.2 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KDO32174.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase TsaE PF02367.17 KDO32174.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hpr_kinase_C PF07475.12 KDO32174.1 - 0.18 11.3 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Myosin_head PF00063.21 KDO32175.1 - 1.2e-217 724.4 0.0 1.6e-217 723.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KDO32175.1 - 0.003 18.0 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PDZ_6 PF17820.1 KDO32175.1 - 0.074 12.9 0.0 4.9 7.1 0.0 2.9 3 0 0 3 3 3 0 PDZ domain AAA_22 PF13401.6 KDO32175.1 - 0.14 12.4 0.0 0.58 10.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.23 KDO32176.1 - 1.3e-20 74.5 0.8 1.4e-20 74.3 0.8 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.6 KDO32176.1 - 0.015 15.9 0.0 0.018 15.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family Peptidase_C1_2 PF03051.15 KDO32176.1 - 0.1 11.4 0.3 0.12 11.1 0.3 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_C1 PF00112.23 KDO32177.1 - 2.8e-52 178.0 8.5 3.4e-52 177.7 8.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO32177.1 - 0.0017 17.3 1.4 0.63 8.7 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.6 KDO32177.1 - 0.041 14.4 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family Peptidase_C1 PF00112.23 KDO32180.1 - 1.1e-56 192.4 12.1 1.9e-56 191.6 12.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO32180.1 - 0.00012 21.1 1.4 0.047 12.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family TPR_17 PF13431.6 KDO32181.1 - 7.7e-09 35.3 2.3 0.041 14.3 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO32181.1 - 3.9e-07 29.7 12.2 0.0015 18.5 2.5 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO32181.1 - 4.2e-07 30.2 30.2 0.019 15.7 1.5 6.4 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO32181.1 - 3.8e-06 26.5 6.0 0.0009 19.0 1.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO32181.1 - 1.5e-05 25.2 17.4 5.1e-05 23.5 2.1 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat F-box-like PF12937.7 KDO32181.1 - 1.9e-05 24.5 1.8 2.8e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 F-box-like TPR_8 PF13181.6 KDO32181.1 - 2.5e-05 24.1 4.4 0.0087 16.2 0.2 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat F-box PF00646.33 KDO32181.1 - 5.8e-05 22.9 0.2 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain TPR_19 PF14559.6 KDO32181.1 - 0.00027 21.4 19.0 0.021 15.3 4.9 4.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO32181.1 - 0.0023 18.5 10.3 0.0023 18.5 10.3 6.4 4 1 3 7 7 7 3 Tetratricopeptide repeat F-box_5 PF18511.1 KDO32181.1 - 0.026 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box TPR_11 PF13414.6 KDO32181.1 - 0.038 13.7 9.8 1.3 8.8 0.2 4.1 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 KDO32181.1 - 0.072 13.2 7.0 1.7 8.9 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO32181.1 - 0.57 10.1 19.3 0.062 13.2 2.7 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO32181.1 - 2.1 9.1 13.8 11 6.9 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat GIT_CC PF16559.5 KDO32182.1 - 0.11 12.3 20.1 0.39 10.6 0.1 6.5 5 1 1 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor OprB PF04966.12 KDO32182.1 - 0.17 11.3 0.6 0.27 10.6 0.6 1.3 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family YojJ PF10372.9 KDO32182.1 - 5.1 7.3 7.2 45 4.2 0.3 4.5 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Myosin_head PF00063.21 KDO32183.1 - 2.3e-208 693.7 0.0 5e-207 689.3 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) PDZ_6 PF17820.1 KDO32183.1 - 7.1e-10 38.6 0.0 0.0012 18.7 0.0 4.4 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 KDO32183.1 - 1.1e-06 28.9 0.0 4.4e-05 23.7 0.0 3.3 4 0 0 4 4 4 1 PDZ domain TsaE PF02367.17 KDO32183.1 - 0.082 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KDO32183.1 - 0.086 13.2 0.0 0.086 13.2 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain IQ PF00612.27 KDO32183.1 - 0.2 11.5 21.2 0.057 13.2 1.6 3.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif Myosin_head PF00063.21 KDO32184.1 - 7.8e-218 725.0 0.0 1e-217 724.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) PDZ_6 PF17820.1 KDO32184.1 - 1.5e-13 50.3 0.2 0.00014 21.6 0.1 3.8 3 0 0 3 3 3 3 PDZ domain IQ PF00612.27 KDO32184.1 - 4.5e-06 26.0 26.0 0.0011 18.6 0.7 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif PDZ PF00595.24 KDO32184.1 - 7.2e-06 26.3 0.0 0.0032 17.8 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO32184.1 - 6.5e-05 23.2 0.0 0.036 14.4 0.0 2.8 2 0 0 2 2 2 2 PDZ domain AAA_16 PF13191.6 KDO32184.1 - 0.042 14.2 0.2 0.69 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Myosin_head PF00063.21 KDO32185.1 - 5.5e-217 722.2 0.0 7.2e-217 721.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) PDZ_6 PF17820.1 KDO32185.1 - 0.0028 17.5 0.1 0.088 12.7 0.0 2.9 3 0 0 3 3 3 1 PDZ domain IQ PF00612.27 KDO32185.1 - 0.027 14.2 22.5 0.31 10.9 0.6 5.1 4 0 0 4 4 4 0 IQ calmodulin-binding motif AAA_19 PF13245.6 KDO32185.1 - 0.061 13.7 0.4 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain PDZ PF00595.24 KDO32185.1 - 0.066 13.6 0.0 26 5.3 0.0 3.6 4 0 0 4 4 4 0 PDZ domain AAA_6 PF12774.7 KDO32185.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KDO32185.1 - 0.16 12.3 0.0 0.93 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO32185.1 - 0.28 11.5 3.4 0.32 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain HA PF03457.14 KDO32186.1 - 3.8e-23 81.6 0.1 0.076 13.4 0.0 7.9 8 0 0 8 8 8 7 Helicase associated domain HYLS1_C PF15311.6 KDO32186.1 - 0.0059 17.3 0.6 66 4.4 0.0 5.1 7 0 0 7 7 7 1 Hydrolethalus syndrome protein 1 C-terminus GOLD_2 PF13897.6 KDO32187.1 - 0.00011 22.8 0.3 0.098 13.1 0.1 2.6 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking Filament PF00038.21 KDO32187.1 - 0.0022 17.6 12.0 0.0022 17.6 12.0 1.8 2 1 0 2 2 2 1 Intermediate filament protein DUF4200 PF13863.6 KDO32187.1 - 0.047 14.1 8.4 0.31 11.5 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MAD PF05557.13 KDO32187.1 - 0.15 10.4 13.4 0.024 13.0 1.2 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein MCPVI PF02993.14 KDO32187.1 - 0.27 11.0 3.2 0.17 11.7 0.7 2.0 2 0 0 2 2 2 0 Minor capsid protein VI Golgin_A5 PF09787.9 KDO32187.1 - 0.62 9.5 16.0 2.1 7.7 4.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 CENP-F_N PF10481.9 KDO32187.1 - 1.9 8.1 9.3 0.53 9.9 2.7 2.2 2 0 0 2 2 2 0 Cenp-F N-terminal domain FAM184 PF15665.5 KDO32187.1 - 2.4 7.9 17.5 1.5 8.5 3.0 2.6 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B SLX9 PF15341.6 KDO32187.1 - 2.9 8.3 7.1 1.3 9.4 1.3 2.5 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Pkinase PF00069.25 KDO32188.1 - 6e-69 232.3 0.0 8e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32188.1 - 3.3e-32 111.8 0.0 4.3e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO32188.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO32188.1 - 0.00035 20.6 0.7 0.0071 16.3 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO32188.1 - 0.00062 19.2 0.2 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO32188.1 - 0.00065 18.6 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF629 PF04780.12 KDO32188.1 - 0.082 11.4 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF2834 PF11196.8 KDO32189.1 - 0.086 13.2 6.8 1.3 9.4 1.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) EF-hand_1 PF00036.32 KDO32190.1 - 2e-25 86.4 8.8 1.4e-06 27.4 0.2 5.5 5 0 0 5 5 5 4 EF hand fn3 PF00041.21 KDO32190.1 - 3.6e-25 88.1 2.2 4.6e-06 26.9 0.0 5.8 5 0 0 5 5 5 4 Fibronectin type III domain EF-hand_7 PF13499.6 KDO32190.1 - 4.8e-25 87.8 6.4 2.7e-12 46.9 0.2 4.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO32190.1 - 9.5e-23 78.6 9.1 5.3e-05 22.5 0.4 5.5 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 KDO32190.1 - 1.2e-20 73.1 8.5 2.6e-05 24.0 0.3 5.4 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.6 KDO32190.1 - 3.6e-20 70.1 9.6 0.00094 18.9 0.2 5.8 5 0 0 5 5 5 5 EF-hand domain Pur_ac_phosph_N PF16656.5 KDO32190.1 - 1.6e-11 44.6 0.7 0.34 11.5 0.0 4.9 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KDO32190.1 - 0.0022 18.3 0.0 1 9.8 0.0 4.0 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) PriCT_2 PF08707.11 KDO32190.1 - 0.0032 17.8 0.8 2.3 8.7 0.2 3.2 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) SPARC_Ca_bdg PF10591.9 KDO32190.1 - 0.0037 17.6 0.5 0.17 12.2 0.0 3.4 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KDO32190.1 - 0.035 14.3 0.1 22 5.4 0.0 3.4 3 0 0 3 3 3 0 Dockerin type I domain Sybindin PF04099.12 KDO32191.1 - 1.9e-40 138.1 0.0 2.2e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KDO32191.1 - 0.00026 21.1 0.0 0.00035 20.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF423 PF04241.15 KDO32191.1 - 0.019 15.2 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Ins145_P3_rec PF08709.11 KDO32192.1 - 6.6e-21 74.5 2.0 3.1e-20 72.3 0.1 2.9 2 2 1 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 KDO32192.1 - 2.3e-11 43.9 3.7 1.8e-05 24.7 0.5 4.0 2 2 0 2 2 2 2 MIR domain RYDR_ITPR PF01365.21 KDO32192.1 - 2e-07 30.6 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RIH domain RIH_assoc PF08454.11 KDO32193.1 - 1.3e-28 98.8 2.0 8.7e-28 96.1 0.7 3.1 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ion_trans PF00520.31 KDO32193.1 - 5.4e-11 42.2 5.7 1.2e-10 41.1 5.7 1.5 1 0 0 1 1 1 1 Ion transport protein RYDR_ITPR PF01365.21 KDO32193.1 - 8e-08 31.9 0.1 5.9e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 RIH domain HHH_6 PF14579.6 KDO32193.1 - 0.055 13.7 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif SKA2 PF16740.5 KDO32193.1 - 0.18 11.6 2.4 1.6 8.5 2.4 2.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Adaptin_binding PF10199.9 KDO32193.1 - 0.33 11.6 1.3 1.1 9.9 1.3 1.9 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Ank_4 PF13637.6 KDO32194.1 - 1.9e-28 98.4 15.8 5.4e-06 26.9 0.1 6.5 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO32194.1 - 9.4e-24 83.8 15.0 5.2e-06 26.9 0.1 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO32194.1 - 4.9e-23 80.9 14.2 0.0049 17.2 0.0 8.9 2 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32194.1 - 1.6e-11 43.3 3.5 2.3 9.1 0.0 9.6 9 1 1 10 10 10 1 Ankyrin repeat Ank PF00023.30 KDO32194.1 - 0.00017 21.9 3.8 4.3 8.0 0.0 6.6 4 2 0 4 4 4 1 Ankyrin repeat DUF3322 PF11795.8 KDO32194.1 - 0.0052 16.8 1.2 6.6 6.7 0.0 3.7 3 2 0 3 3 3 2 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF5049 PF16468.5 KDO32194.1 - 0.016 15.1 0.1 16 5.5 0.0 4.8 4 2 2 6 6 6 0 Domain of unknown function (DUF5049) SAM_3 PF18016.1 KDO32194.1 - 0.068 13.0 0.1 7.6 6.4 0.0 3.1 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) YmaF PF12788.7 KDO32194.1 - 2.3 8.8 9.5 4.9 7.7 0.5 3.3 2 1 1 3 3 3 0 YmaF family IBR PF01485.21 KDO32195.1 - 0.00012 22.2 23.3 0.001 19.3 3.7 4.1 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain UPF0547 PF10571.9 KDO32197.1 - 0.1 12.7 1.6 9.9 6.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C4_Topoisom PF01396.19 KDO32197.1 - 0.28 11.0 2.0 12 5.8 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger F-box PF00646.33 KDO32199.1 - 0.038 13.9 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box domain IBR PF01485.21 KDO32200.1 - 0.00033 20.8 7.4 0.0005 20.2 7.4 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zinc_ribbon_12 PF11331.8 KDO32200.1 - 0.0044 16.8 3.1 0.031 14.1 2.2 2.3 1 1 1 2 2 2 1 Probable zinc-ribbon domain C1_4 PF07975.12 KDO32200.1 - 0.14 12.4 4.0 0.54 10.5 4.1 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain OrfB_Zn_ribbon PF07282.11 KDO32200.1 - 0.28 11.1 3.3 0.47 10.4 3.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PTPS_related PF10131.9 KDO32200.1 - 2.9 6.1 4.2 3.7 5.8 4.2 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF4381 PF14316.6 KDO32201.1 - 0.065 13.5 1.4 0.12 12.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) UbiA PF01040.18 KDO32201.1 - 0.094 12.0 0.2 0.094 12.0 0.2 1.5 2 0 0 2 2 2 0 UbiA prenyltransferase family ATP_sub_h PF10775.9 KDO32201.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase complex subunit h CLASP_N PF12348.8 KDO32202.1 - 3.3e-28 98.8 0.0 4.5e-17 62.4 0.0 4.9 4 1 1 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 KDO32202.1 - 5.8e-06 26.4 1.6 1.3 9.0 0.0 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 KDO32202.1 - 0.00081 18.6 0.4 0.0045 16.2 0.0 2.4 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 KDO32202.1 - 0.0012 19.0 1.6 0.22 11.7 0.0 4.5 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KDO32202.1 - 0.0025 18.2 27.5 0.13 12.7 1.1 7.1 6 2 2 8 8 8 4 HEAT repeats HEAT PF02985.22 KDO32202.1 - 0.083 13.2 26.1 3.3 8.2 0.0 10.0 11 0 0 11 11 11 0 HEAT repeat DUF2555 PF10742.9 KDO32202.1 - 0.15 11.9 0.0 37 4.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) HEAT_EZ PF13513.6 KDO32202.1 - 2.9 8.5 15.7 4 8.0 0.0 7.6 10 0 0 10 10 10 0 HEAT-like repeat SDA1 PF05285.12 KDO32203.1 - 0.24 10.8 14.7 0.31 10.4 14.7 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 KDO32203.1 - 0.52 10.2 10.6 1 9.2 10.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 KDO32203.1 - 0.83 7.9 8.9 1 7.6 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KDO32203.1 - 0.83 9.2 12.0 1.1 8.8 12.0 1.2 1 0 0 1 1 1 0 PPP4R2 Zip PF02535.22 KDO32203.1 - 0.98 8.6 1.8 1.2 8.3 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SURF2 PF05477.11 KDO32203.1 - 1.8 8.2 6.6 2.6 7.7 6.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 KDO32203.1 - 3.1 7.0 16.8 5.2 6.3 16.8 1.4 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_65N PF03636.15 KDO32204.1 - 0.069 12.8 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain IBR PF01485.21 KDO32205.1 - 1.1e-10 41.5 42.4 2e-07 31.1 13.1 3.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain TraX PF05857.11 KDO32205.1 - 0.19 11.8 6.7 0.29 11.2 6.7 1.3 1 0 0 1 1 1 0 TraX protein Imm_superinfect PF14373.6 KDO32205.1 - 4.9 7.1 13.1 2.1 8.4 0.2 2.7 3 0 0 3 3 3 0 Superinfection immunity protein Zf_RING PF16744.5 KDO32206.1 - 3.2 7.9 11.4 0.36 11.0 6.4 2.2 2 1 0 2 2 2 0 KIAA1045 RING finger TrmO PF01980.16 KDO32208.1 - 3.8e-39 133.6 0.0 7.7e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 KDO32208.1 - 0.005 16.9 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 TrmO C-terminal domain IBR PF01485.21 KDO32209.1 - 1.5e-09 37.9 29.3 1.1e-07 32.0 14.8 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain FYVE PF01363.21 KDO32209.1 - 0.033 14.3 6.0 0.033 14.3 6.0 3.3 2 1 1 3 3 3 0 FYVE zinc finger Transket_pyr PF02779.24 KDO32210.1 - 5.1e-59 198.9 0.0 7.7e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KDO32210.1 - 1.8e-52 178.1 0.0 2.4e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KDO32210.1 - 2.3e-44 150.8 0.0 4.1e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal STI1 PF17830.1 KDO32211.1 - 0.00038 20.3 0.3 0.062 13.2 0.2 2.2 2 0 0 2 2 2 2 STI1 domain CBP_BcsO PF17037.5 KDO32211.1 - 0.074 13.2 0.3 0.096 12.8 0.3 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Com_YlbF PF06133.11 KDO32211.1 - 0.13 12.9 0.1 11 6.7 0.0 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Myosin_head PF00063.21 KDO32212.1 - 1.2e-103 347.7 0.0 2.2e-103 346.7 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) PH PF00169.29 KDO32212.1 - 2.5e-13 50.4 0.2 7e-13 49.0 0.0 1.9 2 0 0 2 2 1 1 PH domain PH_11 PF15413.6 KDO32212.1 - 0.00013 22.3 0.1 0.00038 20.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain NACHT PF05729.12 KDO32212.1 - 0.0005 20.0 0.0 0.002 18.1 0.0 2.1 1 0 0 1 1 1 1 NACHT domain PH_8 PF15409.6 KDO32212.1 - 0.0035 17.6 0.6 0.011 16.0 0.6 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain AAA_16 PF13191.6 KDO32212.1 - 0.0039 17.6 0.0 0.031 14.7 0.0 2.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KDO32212.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO32212.1 - 0.025 14.6 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KDO32212.1 - 0.065 13.5 0.0 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO32212.1 - 0.07 13.5 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KDO32212.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glutaredoxin PF00462.24 KDO32212.1 - 0.16 12.2 0.1 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin RNA_helicase PF00910.22 KDO32212.1 - 0.2 12.0 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PH PF00169.29 KDO32213.1 - 0.016 15.7 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 PH domain FliS PF02561.14 KDO32213.1 - 1.1 9.5 6.5 1.1 9.5 1.3 3.2 2 0 0 2 2 2 0 Flagellar protein FliS HTH_Tnp_4 PF13613.6 KDO32214.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF4704 PF15787.5 KDO32217.1 - 0.00017 20.9 0.1 0.00059 19.2 0.2 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) adh_short PF00106.25 KDO32221.1 - 3.2e-43 147.5 2.0 4.1e-43 147.1 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO32221.1 - 2.8e-36 125.3 3.5 3.2e-36 125.0 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO32221.1 - 2.7e-09 37.2 0.5 3.9e-09 36.7 0.5 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KDO32222.1 - 8.9e-40 136.2 0.8 1.3e-39 135.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO32222.1 - 4.9e-30 104.8 1.6 6e-30 104.5 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO32222.1 - 0.0018 18.2 0.2 0.0036 17.2 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF3849 PF12960.7 KDO32222.1 - 0.11 12.4 0.1 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) adh_short PF00106.25 KDO32223.1 - 4.1e-39 134.1 0.7 5.2e-39 133.7 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO32223.1 - 2.9e-32 112.1 0.3 3.6e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO32223.1 - 0.0013 18.7 0.3 0.0018 18.2 0.3 1.3 1 1 0 1 1 1 1 KR domain OprF PF05736.11 KDO32223.1 - 0.058 13.1 0.2 0.082 12.6 0.2 1.2 1 0 0 1 1 1 0 OprF membrane domain EF-hand_7 PF13499.6 KDO32224.1 - 5.6e-08 33.1 0.2 1.3e-07 32.0 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO32224.1 - 3.5e-07 29.3 0.1 0.039 13.5 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO32224.1 - 5.3e-06 25.9 0.1 0.058 13.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain FUSC_2 PF13515.6 KDO32224.1 - 0.15 12.2 29.1 0.15 12.2 9.9 3.6 2 1 0 3 3 3 0 Fusaric acid resistance protein-like EF-hand_8 PF13833.6 KDO32224.1 - 0.19 11.6 0.2 0.64 9.9 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair Ank_2 PF12796.7 KDO32225.1 - 1.6e-14 54.3 8.2 8.5e-05 23.1 0.9 5.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32225.1 - 1.6e-09 38.1 8.9 0.015 15.9 0.5 6.5 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32225.1 - 8.7e-07 28.8 10.7 6 7.8 0.1 8.9 9 1 1 10 10 10 1 Ankyrin repeat Ank_5 PF13857.6 KDO32225.1 - 2.6e-05 24.4 15.0 21 5.6 0.0 8.4 7 2 2 9 9 9 1 Ankyrin repeats (many copies) DUF249 PF03158.13 KDO32225.1 - 0.0037 17.0 0.0 5.5 6.7 0.0 3.2 3 0 0 3 3 3 2 Multigene family 530 protein Ank PF00023.30 KDO32225.1 - 2.9 8.5 16.0 14 6.3 0.4 6.5 5 4 0 5 5 5 0 Ankyrin repeat NAD_binding_8 PF13450.6 KDO32226.1 - 2.9e-13 49.8 0.0 2.6e-10 40.4 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KDO32226.1 - 3.5e-07 29.9 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KDO32226.1 - 3.1e-05 23.7 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KDO32226.1 - 0.0001 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KDO32226.1 - 0.00019 20.8 0.1 0.0003 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KDO32226.1 - 0.00083 18.7 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KDO32226.1 - 0.002 17.3 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KDO32226.1 - 0.004 15.9 0.1 0.0058 15.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KDO32226.1 - 0.03 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KDO32226.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KDO32226.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 KDO32226.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ank_2 PF12796.7 KDO32227.1 - 1.5e-05 25.5 0.1 0.19 12.3 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32227.1 - 0.0019 18.7 0.5 3.2 8.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32227.1 - 0.062 13.6 0.2 0.68 10.3 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32227.1 - 0.093 13.3 2.2 6.3 7.7 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat Ank PF00023.30 KDO32227.1 - 0.1 13.1 4.3 17 6.1 0.2 4.2 3 1 0 3 3 3 0 Ankyrin repeat tRNA-synt_1c PF00749.21 KDO32230.1 - 1.3e-103 346.2 0.0 1.6e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain B2 PF11473.8 KDO32233.1 - 0.037 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA binding protein B2 NleF_casp_inhib PF16809.5 KDO32233.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.5 1 1 0 2 2 2 0 NleF caspase inhibitor FUSC PF04632.12 KDO32233.1 - 0.33 9.4 10.7 0.41 9.1 10.1 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 KDO32233.1 - 4.2 7.2 27.7 2.5 7.9 3.9 4.8 3 2 1 4 4 4 0 Septum formation initiator Fib_alpha PF08702.10 KDO32233.1 - 4.9 7.3 18.1 0.23 11.7 6.5 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ASF1_hist_chap PF04729.13 KDO32234.1 - 2.9e-06 27.3 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone E1_DerP2_DerF2 PF02221.15 KDO32234.1 - 0.073 13.5 0.1 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 ML domain Peptidase_M16_M PF16187.5 KDO32235.1 - 4.4e-61 206.6 0.1 6.2e-61 206.1 0.1 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KDO32235.1 - 2e-33 115.4 0.1 9.2e-31 106.8 0.0 3.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO32235.1 - 2.8e-28 99.2 0.0 1.2e-14 54.8 0.0 4.1 4 1 0 4 4 4 2 Peptidase M16 inactive domain BUD22 PF09073.10 KDO32235.1 - 0.66 9.3 14.4 1.3 8.3 14.4 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KDO32235.1 - 0.67 8.1 22.6 0.95 7.6 22.6 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KDO32235.1 - 0.81 8.1 12.1 1.2 7.5 12.1 1.1 1 0 0 1 1 1 0 Mpp10 protein E2F_CC-MB PF16421.5 KDO32236.1 - 1.8e-24 85.9 0.0 3.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KDO32236.1 - 2.5e-24 85.1 0.1 5.5e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain MAP70 PF07058.11 KDO32236.1 - 0.045 12.5 0.1 0.08 11.7 0.1 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 TrmB PF01978.19 KDO32236.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FWWh PF14922.6 KDO32237.1 - 1.6e-14 54.1 0.3 3.1e-14 53.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function Peptidase_M16_M PF16187.5 KDO32238.1 - 9.7e-33 113.6 0.0 1.4e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KDO32238.1 - 1.1e-30 106.5 0.0 7.3e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO32238.1 - 4.3e-17 62.7 0.0 2.5e-09 37.4 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ank_2 PF12796.7 KDO32239.1 - 2.2e-21 76.2 2.1 9.6e-06 26.1 0.0 5.7 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32239.1 - 3e-14 53.2 11.0 0.27 11.9 0.1 9.2 6 4 3 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32239.1 - 4.7e-13 49.1 12.0 0.43 11.0 0.0 9.4 7 4 3 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32239.1 - 3.8e-11 42.2 9.0 0.99 10.2 0.0 10.4 11 0 0 11 11 11 2 Ankyrin repeat Ank PF00023.30 KDO32239.1 - 0.00059 20.2 11.7 0.85 10.2 0.1 6.6 4 3 0 4 4 4 2 Ankyrin repeat DUF3789 PF12664.7 KDO32239.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Ion_trans PF00520.31 KDO32240.1 - 4.2e-19 68.7 21.9 1.7e-10 40.5 13.9 2.7 2 1 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 KDO32240.1 - 2.1e-16 59.7 0.1 2.3e-08 34.0 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO32240.1 - 2.3e-15 56.3 7.5 1.9e-13 50.2 1.5 2.8 2 0 0 2 2 2 2 Ion channel RGS PF00615.19 KDO32241.1 - 9.3e-30 103.3 0.2 9.6e-17 61.4 0.7 3.2 3 0 0 3 3 3 2 Regulator of G protein signaling domain RGS-like PF09128.11 KDO32241.1 - 0.0042 16.8 0.2 0.037 13.7 0.2 2.1 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain TMEM220 PF15071.6 KDO32241.1 - 0.072 13.8 0.0 1.5 9.6 0.0 2.4 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF2462 PF09495.10 KDO32242.1 - 0.00087 20.0 7.7 0.00087 20.0 7.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) XRN_M PF17846.1 KDO32242.1 - 2.6 6.9 5.2 0.55 9.1 0.8 1.8 1 1 1 2 2 2 0 Xrn1 helical domain TPR_2 PF07719.17 KDO32243.1 - 9.2e-18 62.9 1.1 0.042 14.0 0.0 6.2 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO32243.1 - 1.9e-16 59.1 0.9 0.067 13.0 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KDO32243.1 - 1.3e-14 54.2 5.5 3.6e-05 24.0 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO32243.1 - 1.7e-11 43.3 9.0 0.068 13.4 0.0 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO32243.1 - 9e-11 41.0 2.8 0.75 10.0 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KDO32243.1 - 3.6e-10 40.3 0.0 1.6e-09 38.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO32243.1 - 1.7e-09 38.3 0.0 7.8e-09 36.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO32243.1 - 3.6e-09 36.6 0.0 8.5e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_19 PF14559.6 KDO32243.1 - 1.7e-07 31.6 4.0 0.073 13.6 0.4 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat Methyltransf_12 PF08242.12 KDO32243.1 - 3.6e-07 30.8 0.0 1.4e-06 28.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain TPR_16 PF13432.6 KDO32243.1 - 3.2e-06 27.7 0.6 3.2e-06 27.7 0.6 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO32243.1 - 2.1e-05 24.9 7.0 7.9 7.6 0.1 6.6 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO32243.1 - 9.5e-05 22.8 4.5 11 6.9 0.2 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO32243.1 - 0.00011 22.4 6.4 0.43 10.8 0.1 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KDO32243.1 - 0.00019 21.1 4.5 2 8.2 0.0 5.5 4 2 2 6 6 6 1 TPR repeat TPR_17 PF13431.6 KDO32243.1 - 0.00023 21.3 1.8 4.2 8.0 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 KDO32243.1 - 0.00032 20.6 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPR_10 PF13374.6 KDO32243.1 - 0.004 17.0 1.2 33 4.5 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 KDO32243.1 - 0.025 14.0 0.5 0.11 11.9 0.1 1.9 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP PrmA PF06325.13 KDO32243.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_4 PF07721.14 KDO32243.1 - 0.063 13.9 3.1 11 6.9 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 KDO32243.1 - 0.9 10.0 9.0 1 9.8 0.1 3.7 3 1 0 4 4 3 0 Bacterial transcriptional activator domain Myosin_head PF00063.21 KDO32244.1 - 5.4e-223 742.1 0.1 6.5e-223 741.8 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 KDO32244.1 - 7.2e-32 109.8 5.5 1.4e-10 41.6 0.2 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KDO32244.1 - 2.3e-25 87.9 17.9 0.00016 22.0 0.2 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KDO32244.1 - 9e-24 81.0 10.5 0.014 15.9 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KDO32244.1 - 4e-23 81.2 12.9 2.6e-06 27.6 0.1 7.0 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO32244.1 - 4.7e-23 81.2 10.4 9.2e-07 29.3 0.3 7.2 2 2 6 8 8 8 5 Ankyrin repeats (many copies) FYVE PF01363.21 KDO32244.1 - 8.1e-13 48.3 11.3 8.1e-13 48.3 11.3 1.8 2 0 0 2 2 1 1 FYVE zinc finger IQ PF00612.27 KDO32244.1 - 0.0013 18.3 7.4 0.43 10.5 4.4 3.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_19 PF13245.6 KDO32244.1 - 0.0019 18.5 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SPG48 PF14764.6 KDO32244.1 - 0.0069 16.9 0.0 6.2 7.3 0.0 3.1 3 0 0 3 3 3 1 AP-5 complex subunit, vesicle trafficking AAA_22 PF13401.6 KDO32244.1 - 0.014 15.6 0.1 0.17 12.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO32244.1 - 0.029 14.7 0.2 0.19 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KDO32244.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Nckap1 PF09735.9 KDO32245.1 - 7.1e-34 117.0 0.0 3.4e-24 85.0 0.0 3.3 2 1 0 2 2 2 2 Membrane-associated apoptosis protein Ank_2 PF12796.7 KDO32246.1 - 1.2e-13 51.4 1.8 2.6e-07 31.1 0.1 3.0 1 1 3 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32246.1 - 2e-09 37.8 0.4 6e-06 26.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32246.1 - 1.5e-08 34.2 3.5 0.00044 20.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO32246.1 - 9.6e-07 29.0 1.9 0.004 17.4 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO32246.1 - 0.034 14.6 7.7 0.5 10.9 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat FliG_C PF01706.16 KDO32246.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 FliG C-terminal domain Ank_2 PF12796.7 KDO32247.1 - 1.1e-16 61.2 5.2 2.2e-09 37.8 0.3 2.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32247.1 - 1.3e-12 48.0 2.3 1.3e-07 32.0 0.1 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32247.1 - 2.3e-07 31.0 5.3 0.00088 19.5 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32247.1 - 1.7e-05 24.8 10.1 0.017 15.6 0.1 4.8 6 0 0 6 6 6 2 Ankyrin repeat FCD PF07729.12 KDO32247.1 - 0.039 14.4 0.1 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 FCD domain Ank PF00023.30 KDO32247.1 - 0.091 13.2 0.4 0.091 13.2 0.4 4.4 5 0 0 5 5 5 0 Ankyrin repeat LRR_8 PF13855.6 KDO32248.1 - 1.8e-06 27.6 5.5 0.022 14.5 0.1 2.6 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KDO32248.1 - 8.6e-06 26.0 0.6 0.0011 19.3 0.1 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO32248.1 - 0.0092 15.5 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KDO32248.1 - 0.092 12.8 3.4 32 4.9 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KDO32248.1 - 0.95 10.3 3.1 40 5.3 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO32249.1 - 1 9.9 11.8 3.5 8.2 0.3 5.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KDO32250.1 - 4.1e-44 150.9 0.0 5.8e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32250.1 - 6.3e-44 150.2 0.0 1e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Gal_Lectin PF02140.18 KDO32250.1 - 7.6e-22 77.5 7.1 3e-13 50.0 0.7 3.2 3 1 0 3 3 3 2 Galactose binding lectin domain SKG6 PF08693.10 KDO32250.1 - 6.4e-06 25.5 2.2 1.4e-05 24.4 2.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KDO32250.1 - 0.01 15.6 2.4 0.021 14.6 2.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 KDO32250.1 - 0.012 14.4 0.0 0.027 13.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO32250.1 - 0.047 12.6 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain VPS13_C PF16909.5 KDO32251.1 - 1.3e-46 158.7 0.6 5e-43 146.9 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 KDO32251.1 - 6.3e-34 117.8 6.2 2.9e-17 63.3 3.1 3.9 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KDO32251.1 - 3.2e-23 82.1 0.0 1e-22 80.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KDO32251.1 - 9.5e-19 67.8 0.0 2.9e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KDO32251.1 - 3.9e-18 65.7 0.1 9.3e-17 61.2 0.3 3.0 2 1 0 2 2 2 1 Repeating coiled region of VPS13 PX PF00787.24 KDO32251.1 - 2.6e-16 59.6 0.2 6.7e-16 58.3 0.2 1.7 1 0 0 1 1 1 1 PX domain C2 PF00168.30 KDO32251.1 - 0.0002 21.6 0.0 0.00048 20.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain PDZ PF00595.24 KDO32251.1 - 0.0026 18.1 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain ATG_C PF09333.11 KDO32251.1 - 0.048 14.0 0.0 0.53 10.7 0.0 2.6 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain FYVE PF01363.21 KDO32252.1 - 1.7e-14 53.7 5.2 1.7e-14 53.7 5.2 1.8 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 KDO32252.1 - 0.00079 20.1 0.1 0.0018 18.9 0.1 1.6 1 0 0 1 1 1 1 GAF domain DEP PF00610.21 KDO32252.1 - 0.0034 17.4 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF5117 PF17148.4 KDO32252.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) PH PF00169.29 KDO32252.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 PH domain GAF_3 PF13492.6 KDO32252.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 GAF domain FlxA PF14282.6 KDO32252.1 - 0.29 11.2 8.9 0.6 10.1 8.9 1.5 1 0 0 1 1 1 0 FlxA-like protein FYVE_2 PF02318.16 KDO32252.1 - 1.3 9.3 8.9 0.072 13.3 2.5 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_M18 PF02127.15 KDO32253.1 - 3.6e-157 523.6 0.0 4e-157 523.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KDO32253.1 - 0.03 13.4 0.0 0.52 9.3 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase MYEOV2 PF15004.6 KDO32253.1 - 0.24 11.8 0.6 2.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Myeloma-overexpressed-like Glyco_transf_8 PF01501.20 KDO32254.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 8 p25-alpha PF05517.12 KDO32256.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 p25-alpha EF-hand_8 PF13833.6 KDO32257.1 - 1.3e-06 28.2 0.2 2.1e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair Vert_HS_TF PF06546.11 KDO32257.1 - 0.0099 15.6 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 1 Vertebrate heat shock transcription factor EF-hand_4 PF12763.7 KDO32257.1 - 0.014 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KDO32257.1 - 0.053 14.0 0.1 0.089 13.3 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair Glyoxalase_5 PF14696.6 KDO32258.1 - 7.1e-07 29.5 0.5 2.6e-05 24.4 0.1 2.9 4 0 0 4 4 4 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 KDO32258.1 - 1.4e-06 28.5 0.5 0.0045 17.2 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KDO32258.1 - 2.2e-06 27.9 0.1 0.019 15.2 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF763 PF05559.11 KDO32259.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Lipase_3 PF01764.25 KDO32260.1 - 6.9e-18 64.9 0.0 1.6e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) V-ATPase_H_N PF03224.14 KDO32260.1 - 6.9e-10 38.7 18.0 0.13 11.5 0.0 8.5 6 3 1 8 8 8 4 V-ATPase subunit H Arm PF00514.23 KDO32260.1 - 1.8e-08 34.1 67.2 0.0018 18.2 0.2 17.9 19 1 1 20 20 18 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KDO32260.1 - 1.1e-05 25.4 10.2 0.18 11.9 0.0 7.0 6 0 0 6 6 6 2 Spinocerebellar ataxia type 10 protein domain KAP PF05804.12 KDO32260.1 - 2.9e-05 22.4 4.7 0.39 8.8 0.0 4.9 4 1 0 4 4 4 2 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 KDO32260.1 - 4.3e-05 23.8 28.3 0.67 10.4 0.0 11.9 13 1 0 13 13 13 2 HEAT repeats V-ATPase_H_C PF11698.8 KDO32260.1 - 0.0015 18.6 6.8 11 6.2 0.0 7.0 8 0 0 8 8 8 1 V-ATPase subunit H Cnd1 PF12717.7 KDO32260.1 - 0.0022 18.1 16.3 0.48 10.5 0.0 7.3 7 0 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Abhydrolase_6 PF12697.7 KDO32260.1 - 0.0061 17.2 0.2 0.0061 17.2 0.2 5.1 5 1 0 5 5 4 1 Alpha/beta hydrolase family HEAT PF02985.22 KDO32260.1 - 0.018 15.2 21.4 1.1 9.7 0.1 10.3 10 0 0 10 10 9 0 HEAT repeat HEAT_EZ PF13513.6 KDO32260.1 - 0.08 13.5 33.8 2.5 8.7 0.0 11.7 14 0 0 14 14 13 0 HEAT-like repeat Lipase PF00151.19 KDO32260.1 - 0.22 10.8 0.0 0.52 9.6 0.0 1.5 2 0 0 2 2 2 0 Lipase Arm PF00514.23 KDO32261.1 - 0.0072 16.3 0.1 0.0072 16.3 0.1 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KDO32261.1 - 0.0086 16.0 7.7 0.3 11.0 1.5 3.7 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central DUF2013 PF09431.10 KDO32261.1 - 0.65 10.2 7.1 0.5 10.5 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2013) Methyltransf_25 PF13649.6 KDO32264.1 - 4.1e-05 24.2 0.0 0.0032 18.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO32264.1 - 0.00016 22.3 0.0 0.0004 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO32264.1 - 0.0003 20.6 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO32264.1 - 0.0018 18.2 0.0 0.0039 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO32264.1 - 0.016 15.8 0.0 0.06 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 KDO32264.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.7 KDO32267.1 - 0.0011 19.4 19.7 1.7 9.2 0.3 7.2 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO32267.1 - 0.28 11.0 24.6 1.6 8.5 0.1 7.5 6 3 1 7 7 7 0 Leucine rich repeat LuxS PF02664.15 KDO32268.1 - 0.0011 18.6 0.1 1.4 8.6 0.0 2.2 2 0 0 2 2 2 2 S-Ribosylhomocysteinase (LuxS) zf-CCCH PF00642.24 KDO32268.1 - 0.049 13.6 0.4 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.24 KDO32269.1 - 0.022 14.6 1.1 0.079 12.9 0.3 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SRR1 PF07985.12 KDO32270.1 - 6.6e-11 42.1 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 SRR1 ECH_2 PF16113.5 KDO32272.1 - 1.7e-114 382.8 0.0 3.2e-114 381.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KDO32272.1 - 1.5e-33 116.2 0.0 6.6e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase PH PF00169.29 KDO32273.1 - 7.3e-20 71.4 1.8 1.3e-09 38.5 0.5 3.1 3 1 0 3 3 3 2 PH domain PH_11 PF15413.6 KDO32273.1 - 1.5e-06 28.6 8.0 0.035 14.5 0.2 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 KDO32273.1 - 8.1e-06 26.0 0.2 0.00082 19.6 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KDO32273.1 - 0.0029 17.7 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 PH domain PH PF00169.29 KDO32274.1 - 5.8e-23 81.4 1.1 1.9e-10 41.2 0.0 3.0 3 1 0 3 3 3 2 PH domain PH_8 PF15409.6 KDO32274.1 - 1.2e-11 44.7 0.8 2.1e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KDO32274.1 - 8.9e-11 42.2 10.5 0.00014 22.2 2.0 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KDO32274.1 - 0.00011 22.3 0.0 0.088 12.9 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KDO32274.1 - 0.033 14.5 0.6 0.85 10.0 0.2 2.7 2 2 0 2 2 2 0 Pleckstrin homology domain zf-H2C2_2 PF13465.6 KDO32275.1 - 9.7e-15 54.2 36.0 2.1e-06 27.9 2.6 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KDO32275.1 - 1.2e-14 53.8 41.7 0.00013 22.2 1.3 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO32275.1 - 8.1e-06 26.3 48.5 0.024 15.5 1.5 7.1 7 1 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 KDO32275.1 - 0.00019 21.7 4.2 1.7 9.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KDO32275.1 - 0.0019 17.9 21.7 0.0042 16.8 0.9 4.6 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KDO32275.1 - 0.01 15.9 13.6 0.16 12.0 0.5 4.9 5 0 0 5 5 5 1 C2H2-type zinc finger DUF3446 PF11928.8 KDO32275.1 - 0.022 15.1 7.8 0.022 15.1 7.8 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain ROK PF00480.20 KDO32275.1 - 0.031 13.8 0.3 0.053 13.0 0.3 1.4 1 0 0 1 1 1 0 ROK family zf-C2H2_jaz PF12171.8 KDO32275.1 - 0.95 9.8 10.0 12 6.3 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF116 PF01976.17 KDO32275.1 - 9.7 5.7 9.7 3.3 7.2 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF116 Fib_alpha PF08702.10 KDO32276.1 - 0.52 10.5 15.7 0.69 10.1 1.1 3.4 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family YejG PF13989.6 KDO32276.1 - 0.73 10.3 5.2 0.64 10.5 0.4 2.8 2 1 1 3 3 3 0 YejG-like protein UCH_C PF18031.1 KDO32276.1 - 3.6 7.6 9.0 3.3 7.7 0.3 3.5 4 0 0 4 4 4 0 Ubiquitin carboxyl-terminal hydrolases UFD1 PF03152.14 KDO32277.1 - 3.1e-31 108.2 0.0 4.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 KDO32277.1 - 2.3e-08 34.1 0.0 5.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain TMEM215 PF15746.5 KDO32277.1 - 0.18 11.2 0.4 0.28 10.6 0.4 1.2 1 0 0 1 1 1 0 TMEM215 family SIMPL PF04402.14 KDO32277.1 - 0.7 10.3 8.2 0.21 12.0 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF541) Exonuc_VII_L PF02601.15 KDO32277.1 - 1.8 8.1 7.8 0.52 9.8 4.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit CLU PF13236.6 KDO32278.1 - 3.3e-30 105.6 0.0 1.2e-29 103.8 0.0 1.9 2 0 0 2 2 2 1 Clustered mitochondria LRR_6 PF13516.6 KDO32278.1 - 7.1e-17 60.0 34.6 0.073 13.2 0.0 13.8 16 0 0 16 16 16 6 Leucine Rich repeat Laminin_G_3 PF13385.6 KDO32278.1 - 2.9e-13 50.3 0.1 2.4e-11 44.0 0.1 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily LRR_4 PF12799.7 KDO32278.1 - 1.6e-12 47.4 1.9 0.54 10.8 0.0 7.4 5 2 0 7 7 7 4 Leucine Rich repeats (2 copies) eIF3_p135 PF12807.7 KDO32278.1 - 0.00016 21.7 0.0 0.00047 20.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 SAM_Ste50p PF09235.10 KDO32278.1 - 0.041 14.1 3.0 30 4.9 0.1 4.4 4 0 0 4 4 4 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 KDO32278.1 - 2 9.3 10.2 3.6e+02 2.4 0.0 7.3 9 0 0 9 9 9 0 Leucine Rich Repeat BT1 PF03092.16 KDO32279.1 - 1.7e-08 33.2 3.3 1.7e-08 33.2 3.3 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO32279.1 - 0.0011 18.1 0.7 0.0011 18.1 0.7 2.8 3 0 0 3 3 3 1 PUCC protein SieB PF14163.6 KDO32279.1 - 0.19 11.2 0.1 0.8 9.2 0.0 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B Jacalin PF01419.17 KDO32280.1 - 1e-18 67.6 0.0 4.7e-08 33.0 0.0 2.7 2 0 0 2 2 2 2 Jacalin-like lectin domain Metallopep PF12044.8 KDO32280.1 - 5.3e-07 28.6 0.1 0.00091 17.9 0.3 2.2 2 0 0 2 2 2 2 Putative peptidase family Peptidase_M10 PF00413.24 KDO32280.1 - 0.22 11.4 0.2 0.36 10.6 0.2 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.11 KDO32280.1 - 0.23 11.4 0.0 0.41 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 N6-adenineMlase PF10237.9 KDO32287.1 - 5.5e-38 130.3 0.1 6.5e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase zf-HC2 PF13490.6 KDO32287.1 - 0.032 14.5 0.7 0.062 13.6 0.7 1.5 1 0 0 1 1 1 0 Putative zinc-finger Cystatin PF00031.21 KDO32288.1 - 0.024 14.9 2.8 0.72 10.2 0.3 2.2 2 0 0 2 2 2 0 Cystatin domain Herpeto_peptide PF14409.6 KDO32288.1 - 0.11 12.8 0.3 4.9 7.5 0.1 2.7 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Herpetosiphon Cystatin PF00031.21 KDO32289.1 - 7.3e-11 42.2 2.4 0.0046 17.2 0.2 3.4 3 0 0 3 3 3 3 Cystatin domain SQAPI PF16845.5 KDO32289.1 - 8.2e-05 22.9 1.6 9.5 6.6 0.0 3.8 4 0 0 4 4 4 3 Aspartic acid proteinase inhibitor FAM194 PF14977.6 KDO32290.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein LRR_4 PF12799.7 KDO32291.1 - 2.7e-11 43.5 16.2 0.00012 22.4 1.5 3.3 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO32291.1 - 2.3e-08 33.7 25.7 1.3e-05 24.8 4.3 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KDO32291.1 - 3.3e-08 33.2 0.8 8.5e-08 31.9 0.3 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KDO32291.1 - 0.0031 17.8 7.5 9.2 7.3 0.0 4.5 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KDO32291.1 - 0.0039 17.1 3.9 3 8.1 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat Redoxin PF08534.10 KDO32295.1 - 2.9e-28 98.4 0.0 3.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KDO32295.1 - 4.1e-07 29.9 0.0 5.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO32296.1 - 2.7e-33 114.8 0.0 3e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KDO32296.1 - 3.1e-09 36.8 0.0 3.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KDO32297.1 - 4.1e-34 117.4 0.0 4.6e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KDO32297.1 - 1.2e-06 28.4 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Ion_trans PF00520.31 KDO32298.1 - 7.7e-09 35.1 4.1 7.7e-09 35.1 4.1 2.8 2 1 0 2 2 2 1 Ion transport protein RIH_assoc PF08454.11 KDO32298.1 - 2.1e-07 30.7 2.6 7.5e-07 28.9 1.8 2.4 2 1 0 2 2 2 1 RyR and IP3R Homology associated DNA_pol_phi PF04931.13 KDO32302.1 - 0.21 9.7 1.3 0.29 9.2 1.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KDO32302.1 - 2 8.8 9.3 4.6 7.7 9.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TIP120 PF08623.10 KDO32303.1 - 3.7e-07 30.1 0.1 0.029 14.2 0.0 2.8 3 0 0 3 3 3 2 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KDO32303.1 - 1.7e-06 27.7 10.5 9 6.9 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KDO32303.1 - 3.4e-06 27.4 1.2 0.61 10.5 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KDO32303.1 - 7.2e-05 23.2 6.4 0.28 11.7 0.0 4.8 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KDO32303.1 - 0.00016 21.7 0.4 20 5.2 0.0 4.0 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KDO32303.1 - 0.055 14.1 0.1 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 KDO32303.1 - 0.11 12.1 0.5 6.1 6.3 0.0 2.6 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Apolipoprotein PF01442.18 KDO32304.1 - 0.035 14.0 7.1 0.088 12.7 7.1 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MCPVI PF02993.14 KDO32304.1 - 0.86 9.4 4.6 0.34 10.7 0.8 2.3 2 0 0 2 2 2 0 Minor capsid protein VI DUF4246 PF14033.6 KDO32305.1 - 4.6e-10 39.2 0.0 1.5e-08 34.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4246) DUF5447 PF17525.2 KDO32305.1 - 0.14 12.7 0.7 0.3 11.6 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5447) B2 PF11473.8 KDO32306.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding protein B2 Retrotran_gag_2 PF14223.6 KDO32307.1 - 0.00013 21.7 0.0 0.00029 20.5 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type VBS PF08913.10 KDO32308.1 - 0.05 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Vinculin Binding Site PBP1_TM PF14812.6 KDO32308.1 - 4 7.9 7.3 9.6 6.7 7.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_DNA-binding PF00249.31 KDO32309.1 - 8.4e-09 35.5 0.2 6.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO32309.1 - 2.4e-06 27.7 0.0 0.025 14.8 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ank_2 PF12796.7 KDO32310.1 - 1.1e-17 64.4 0.2 1.9e-10 41.2 0.1 4.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32310.1 - 1.1e-13 51.4 2.7 3.1e-07 30.8 0.5 5.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32310.1 - 1.1e-11 43.8 7.7 0.0013 19.1 0.1 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KDO32310.1 - 1.3e-08 34.9 7.0 4.3e-06 26.9 0.4 4.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO32310.1 - 6.8e-05 23.1 10.9 0.059 13.9 1.0 6.1 7 0 0 7 7 7 2 Ankyrin repeat DUF4246 PF14033.6 KDO32311.1 - 6.7e-14 51.8 0.0 9.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4246 PF14033.6 KDO32312.1 - 0.001 18.3 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ank_2 PF12796.7 KDO32313.1 - 2e-17 63.5 9.6 2.5e-05 24.8 0.0 4.6 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32313.1 - 3.4e-13 49.8 6.2 5.2e-05 23.7 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32313.1 - 1.2e-10 41.4 9.2 0.016 15.5 0.2 6.9 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32313.1 - 8.6e-08 31.9 8.0 0.53 11.0 0.0 7.1 7 1 1 8 8 8 3 Ankyrin repeat Ank PF00023.30 KDO32313.1 - 0.0011 19.3 7.4 19 5.9 0.6 6.4 3 2 2 5 5 5 2 Ankyrin repeat Pho88 PF10032.9 KDO32314.1 - 1.4e-32 112.4 0.0 2.1e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 KDO32314.1 - 5.7e-13 49.3 0.0 1.9e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32314.1 - 8.7e-09 35.8 0.0 2.2e-07 31.3 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KDO32314.1 - 3.9e-08 33.4 0.1 0.017 15.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO32314.1 - 5e-08 32.6 0.0 0.031 14.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KDO32314.1 - 0.0059 16.9 0.1 0.064 13.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RIX1 PF08167.12 KDO32315.1 - 3.7e-08 33.3 0.0 7.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis CRM1_C PF08767.11 KDO32315.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal SAPS PF04499.15 KDO32315.1 - 0.14 10.9 0.7 0.28 9.9 0.7 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TLP-20 PF06088.11 KDO32315.1 - 4.7 7.1 10.0 0.38 10.6 5.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SDA1 PF05285.12 KDO32315.1 - 5.2 6.4 17.1 8.8 5.6 17.1 1.2 1 0 0 1 1 1 0 SDA1 SdrD_B PF17210.3 KDO32316.1 - 0.075 13.3 0.9 0.44 10.8 0.1 2.0 2 0 0 2 2 2 0 SdrD B-like domain HAD_2 PF13419.6 KDO32317.1 - 1.3e-20 74.2 0.0 6.5e-20 72.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO32317.1 - 7.9e-18 65.5 0.0 2.9e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO32317.1 - 2.5e-08 33.8 0.0 6.9e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KDO32317.1 - 2.5e-05 24.8 0.0 8.1e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Adap_comp_sub PF00928.21 KDO32319.1 - 1.2e-21 77.3 0.0 4.9e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Mcm10 PF09332.11 KDO32319.1 - 0.019 14.4 5.4 0.035 13.6 5.4 1.3 1 0 0 1 1 1 0 Mcm10 replication factor DUF3240 PF11582.8 KDO32319.1 - 0.074 13.2 0.5 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) PIEZO PF15917.5 KDO32319.1 - 0.12 11.9 1.1 0.17 11.3 1.1 1.2 1 0 0 1 1 1 0 Piezo Pro_CA PF00484.19 KDO32320.1 - 1.8e-49 168.0 0.4 2.6e-49 167.5 0.4 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Acetyltransf_CG PF14542.6 KDO32321.1 - 6.6e-20 71.0 0.0 8.5e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KDO32321.1 - 9.8e-06 25.8 0.0 1.1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO32321.1 - 0.00044 20.6 0.0 0.00054 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO32321.1 - 0.0068 16.3 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO32321.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DZR PF12773.7 KDO32324.1 - 0.7 10.0 9.0 1.7 8.7 9.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 KDO32324.1 - 2 8.6 10.8 4.9 7.4 10.8 1.7 1 0 0 1 1 1 0 B-box zinc finger GTP_EFTU PF00009.27 KDO32325.1 - 2.9e-64 216.2 0.1 4.6e-64 215.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KDO32325.1 - 4.6e-29 100.6 0.0 3.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KDO32325.1 - 5.9e-21 74.3 0.1 2.5e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KDO32325.1 - 1.6e-14 53.7 0.0 3.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KDO32325.1 - 6.7e-13 48.8 0.0 2.2e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO32325.1 - 0.0018 18.4 0.0 0.0059 16.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Corazonin PF17308.2 KDO32325.1 - 0.17 12.3 0.0 0.44 10.9 0.0 1.6 2 0 0 2 2 2 0 Pro-corazonin PEPCK_ATP PF01293.20 KDO32326.1 - 3.3e-197 655.8 0.1 5.3e-197 655.1 0.1 1.3 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase EstA_Ig_like PF18435.1 KDO32327.1 - 0.057 13.6 0.1 3.7 7.7 0.0 2.3 1 1 1 2 2 2 0 Esterase Ig-like N-terminal domain DUF2807 PF10988.8 KDO32328.1 - 1.4e-10 41.3 8.9 6.5e-07 29.3 1.4 2.2 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain ETC_C1_NDUFA4 PF04800.12 KDO32330.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region Pkinase_Tyr PF07714.17 KDO32331.1 - 2.5e-53 181.0 0.0 3.6e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO32331.1 - 4.4e-48 163.9 0.0 7.3e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cofilin_ADF PF00241.20 KDO32331.1 - 8.3e-07 28.8 0.0 3.5e-05 23.6 0.0 3.1 2 2 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Pkinase_fungal PF17667.1 KDO32331.1 - 0.0028 16.5 0.1 0.0059 15.4 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO32331.1 - 0.0054 16.1 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO32331.1 - 0.006 16.5 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ubiquitin_2 PF14560.6 KDO32331.1 - 0.0069 16.8 0.0 0.032 14.7 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-like domain RPN2_C PF18004.1 KDO32331.1 - 0.064 13.2 0.6 0.12 12.3 0.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1690 PF07956.11 KDO32331.1 - 0.17 12.3 2.7 0.38 11.2 2.7 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ubiquitin PF00240.23 KDO32331.1 - 0.18 11.6 0.0 0.73 9.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family FTA2 PF13095.6 KDO32331.1 - 0.21 11.2 1.4 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Actin PF00022.19 KDO32332.1 - 6.6e-38 130.4 0.0 3.3e-19 68.8 0.0 3.0 2 1 1 3 3 3 3 Actin MreB_Mbl PF06723.13 KDO32332.1 - 0.23 10.3 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein SPC12 PF06645.13 KDO32334.1 - 7.4e-21 74.0 2.0 8.1e-21 73.9 2.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Peptidase_C1 PF00112.23 KDO32335.1 - 3.2e-43 148.4 0.1 4.4e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO32335.1 - 1e-05 24.5 1.6 0.0001 21.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family adh_short_C2 PF13561.6 KDO32336.1 - 1.4e-48 165.5 3.7 1.7e-48 165.3 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO32336.1 - 7.5e-44 149.5 0.6 9.3e-44 149.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO32336.1 - 1.5e-13 51.0 0.7 2.5e-13 50.3 0.7 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 KDO32336.1 - 0.011 16.3 0.5 0.029 14.9 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 KDO32336.1 - 0.027 13.6 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO32336.1 - 0.059 12.5 0.1 0.088 11.9 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KDO32336.1 - 0.068 12.6 0.2 0.14 11.5 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KDO32336.1 - 0.086 13.5 0.0 0.25 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 KDO32336.1 - 0.14 11.4 2.8 0.47 9.6 0.7 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LRR_8 PF13855.6 KDO32337.1 - 1.2e-21 76.3 32.7 4.9e-06 26.2 1.1 7.5 5 2 5 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KDO32337.1 - 9.5e-21 73.6 27.9 8.9e-05 22.8 0.2 7.3 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) ubiquitin PF00240.23 KDO32337.1 - 0.00038 20.2 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KDO32337.1 - 0.0057 17.1 0.0 0.027 14.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain LRR_9 PF14580.6 KDO32337.1 - 0.011 15.2 0.7 0.24 10.9 0.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 KDO32337.1 - 0.037 14.5 27.9 4.6 8.2 0.0 8.2 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO32337.1 - 0.34 11.1 23.3 2.8 8.2 0.5 6.5 7 0 0 7 7 7 0 Leucine Rich repeat FYVE PF01363.21 KDO32338.1 - 4.8e-16 58.6 10.8 1.1e-15 57.5 10.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_3 PF13492.6 KDO32338.1 - 3.9e-09 36.9 0.7 2.2e-08 34.5 0.1 2.3 2 0 0 2 2 2 1 GAF domain MBA1 PF07961.11 KDO32338.1 - 0.0071 15.4 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 MBA1-like protein FYVE_2 PF02318.16 KDO32338.1 - 0.063 13.5 9.2 0.037 14.2 3.1 3.0 3 0 0 3 3 3 0 FYVE-type zinc finger Snapin_Pallidin PF14712.6 KDO32338.1 - 0.18 12.3 3.1 0.34 11.4 3.1 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Phage_GPO PF05929.11 KDO32338.1 - 0.18 11.4 1.7 0.32 10.6 1.1 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Vps53_N PF04100.12 KDO32338.1 - 0.2 10.6 2.2 0.29 10.0 2.2 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF1664 PF07889.12 KDO32338.1 - 0.66 10.0 2.5 1.2 9.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C2H2_4 PF13894.6 KDO32338.1 - 2.8 9.0 9.9 6.2 7.9 5.0 3.3 1 1 1 2 2 2 0 C2H2-type zinc finger Arm PF00514.23 KDO32339.1 - 9.7e-60 196.9 27.3 4.2e-12 45.7 0.0 9.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KDO32339.1 - 1e-16 61.0 9.5 3.8e-06 27.3 0.2 6.6 5 2 1 6 6 5 4 HEAT-like repeat HEAT_2 PF13646.6 KDO32339.1 - 2.7e-15 56.5 0.2 3.6e-05 24.0 0.0 5.5 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 KDO32339.1 - 2e-11 43.1 10.4 0.077 13.3 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat NopRA1 PF16201.5 KDO32339.1 - 1.6e-06 27.8 0.3 0.00094 18.8 0.0 3.6 3 1 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Arm_2 PF04826.13 KDO32339.1 - 5e-06 26.2 0.1 0.015 14.7 0.0 2.7 2 1 1 3 3 3 2 Armadillo-like Arm_3 PF16186.5 KDO32339.1 - 0.00015 21.3 4.7 0.087 12.4 0.0 3.4 3 0 0 3 3 2 2 Atypical Arm repeat V-ATPase_H_C PF11698.8 KDO32339.1 - 0.00063 19.8 0.2 0.53 10.4 0.0 4.3 5 1 1 6 6 5 1 V-ATPase subunit H RICTOR_V PF14668.6 KDO32339.1 - 0.0013 18.9 0.7 4.5 7.6 0.0 4.1 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 KDO32339.1 - 0.0043 17.0 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Cwf_Cwc_15 PF04889.12 KDO32339.1 - 0.031 14.0 19.8 0.05 13.3 19.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Atx10homo_assoc PF09759.9 KDO32339.1 - 0.061 13.4 0.0 8.9 6.4 0.0 3.7 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain VEFS-Box PF09733.9 KDO32339.1 - 0.11 12.3 2.8 0.35 10.7 2.8 1.9 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF913 PF06025.12 KDO32339.1 - 0.24 10.3 3.3 0.53 9.2 3.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Slu7 PF11708.8 KDO32339.1 - 0.38 10.5 16.6 0.58 9.9 16.6 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Glyco_transf_8C PF08437.10 KDO32339.1 - 0.39 10.8 2.6 0.93 9.6 2.6 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal DUF1168 PF06658.12 KDO32339.1 - 0.58 10.0 21.6 1.1 9.0 21.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CTNNBL PF08216.11 KDO32339.1 - 0.65 10.2 11.2 4 7.6 0.0 5.0 5 0 0 5 5 4 0 Catenin-beta-like, Arm-motif containing nuclear TFIIF_alpha PF05793.12 KDO32339.1 - 0.86 8.1 18.8 1.2 7.6 18.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_UL32 PF06070.11 KDO32339.1 - 1.9 6.2 15.0 2.7 5.6 15.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Smg8_Smg9 PF10220.9 KDO32339.1 - 2.3 6.4 14.0 3.2 6.0 14.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 CMS1 PF14617.6 KDO32339.1 - 5.6 6.2 9.8 9.9 5.4 9.8 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Dicty_REP PF05086.12 KDO32339.1 - 5.8 4.8 10.3 7.6 4.4 10.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 KDO32339.1 - 6.4 5.4 12.8 10 4.8 12.8 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KDO32339.1 - 8.9 4.3 15.4 13 3.8 15.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 KDO32339.1 - 9.5 5.1 10.9 14 4.5 10.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MFS_1 PF07690.16 KDO32340.1 - 6.4e-33 114.1 25.6 6.4e-33 114.1 25.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO32340.1 - 3.5e-26 91.6 14.2 3.6e-20 71.8 1.3 3.4 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO32340.1 - 4.1e-15 55.6 19.7 1.6e-14 53.6 19.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.21 KDO32340.1 - 0.31 9.8 5.5 0.044 12.6 1.1 1.9 2 1 0 2 2 2 0 POT family DUF543 PF04418.12 KDO32340.1 - 0.45 10.5 5.3 1.3 9.1 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) RCC1 PF00415.18 KDO32342.1 - 4.2e-42 142.5 8.6 4.2e-10 40.1 0.0 7.2 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO32342.1 - 8.4e-21 73.3 25.8 5.3e-08 32.5 0.1 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 KDO32342.1 - 0.77 9.7 6.7 0.27 11.1 0.4 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif SPRY PF00622.28 KDO32343.1 - 8.8e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 KDO32343.1 - 4.1e-05 23.4 0.0 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KDO32343.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain DUF1299 PF06975.11 KDO32343.1 - 0.34 11.0 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) BTB_2 PF02214.22 KDO32346.1 - 2.2e-11 44.0 0.0 3.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-RING_2 PF13639.6 KDO32352.1 - 0.0067 16.7 10.6 0.0067 16.7 10.6 4.0 3 1 1 4 4 4 1 Ring finger domain Anoctamin PF04547.12 KDO32354.1 - 1.3e-119 400.0 9.6 1.7e-119 399.7 9.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 KDO32354.1 - 9.8e-05 21.8 1.0 9.8e-05 21.8 1.0 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate ActA PF05058.12 KDO32354.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 ActA Protein DUF2207 PF09972.9 KDO32354.1 - 8.1 5.1 7.3 2.2 6.9 1.3 2.2 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) Methyltransf_25 PF13649.6 KDO32355.1 - 1.8e-08 35.0 0.1 1.2e-07 32.3 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO32355.1 - 5.2e-08 33.4 0.0 2.2e-07 31.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO32355.1 - 2.3e-07 30.8 0.0 1.4e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO32355.1 - 2.1e-05 24.3 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO32355.1 - 0.00012 22.7 0.0 0.00025 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_8 PF13181.6 KDO32355.1 - 0.00031 20.7 0.0 0.00068 19.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 KDO32355.1 - 0.00049 20.4 0.0 0.00093 19.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TPR_2 PF07719.17 KDO32355.1 - 0.0045 17.0 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO32355.1 - 0.0056 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO32355.1 - 0.0081 16.5 0.0 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO32355.1 - 0.014 15.0 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 KDO32355.1 - 0.015 16.1 0.1 4.2 8.4 0.0 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO32355.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO32355.1 - 0.04 14.4 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO32355.1 - 0.054 13.5 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 KDO32355.1 - 0.21 11.3 0.1 1.2 8.9 0.1 2.1 1 1 0 1 1 1 0 Lysine methyltransferase NTP_transf_2 PF01909.23 KDO32357.1 - 4e-09 36.6 0.0 9.7e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KDO32357.1 - 0.0062 16.7 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KDO32357.1 - 0.0084 16.2 0.0 0.022 14.8 0.0 1.7 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Cytomega_gL PF01801.16 KDO32357.1 - 0.055 12.9 1.0 0.081 12.3 0.0 1.8 3 0 0 3 3 3 0 Cytomegalovirus glycoprotein L LCM PF04072.14 KDO32358.1 - 1.4e-25 90.3 0.0 6.6e-25 88.2 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_1 PF00583.25 KDO32358.1 - 8.5e-13 48.6 0.1 1.7e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO32358.1 - 4.1e-09 36.7 0.0 8.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KDO32358.1 - 7.2e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO32358.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KDO32358.1 - 0.0019 18.9 0.0 0.0046 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KDO32358.1 - 0.0021 18.2 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PALP PF00291.25 KDO32361.1 - 2.1e-75 253.8 0.6 2.6e-75 253.6 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_N PF00288.26 KDO32361.1 - 0.24 11.7 6.6 5.2 7.4 0.1 3.3 3 1 0 3 3 3 0 GHMP kinases N terminal domain Sugar_tr PF00083.24 KDO32362.1 - 1.7e-113 379.9 27.3 3.6e-86 289.8 14.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO32362.1 - 1.6e-29 103.0 41.8 1.9e-27 96.2 26.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KDO32362.1 - 0.00032 19.2 1.2 0.00068 18.2 1.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PSI PF01437.25 KDO32362.1 - 0.00084 19.8 8.0 0.00084 19.8 8.0 2.1 2 0 0 2 2 2 1 Plexin repeat CarS-like PF01864.17 KDO32362.1 - 0.006 16.6 3.0 0.013 15.5 3.0 1.5 1 0 0 1 1 1 1 CDP-archaeol synthase 2OG-FeII_Oxy_2 PF13532.6 KDO32363.1 - 2.5e-26 93.1 0.0 3.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KDO32363.1 - 3.6e-08 33.4 0.5 5.5e-08 32.8 0.5 1.3 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 KDO32363.1 - 0.011 15.4 0.6 2.8 7.7 0.1 2.8 2 1 0 2 2 2 0 CUE domain DNA_binding_1 PF01035.20 KDO32364.1 - 4.9e-24 84.3 0.0 6.5e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DSPc PF00782.20 KDO32365.1 - 3e-22 78.8 0.0 3.8e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KDO32365.1 - 4.9e-05 23.6 0.1 8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KDO32365.1 - 0.17 11.8 0.3 0.31 11.0 0.3 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO32365.1 - 0.21 11.1 0.2 0.41 10.2 0.1 1.5 1 1 1 2 2 2 0 Protein-tyrosine phosphatase PIP49_N PF14875.6 KDO32366.1 - 0.48 10.3 3.4 0.66 9.8 3.4 1.1 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 DUF4539 PF15072.6 KDO32367.1 - 1.1e-18 67.0 0.0 2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Malate_synthase PF01274.22 KDO32368.1 - 1.7e-91 307.1 0.0 3.6e-91 306.0 0.0 1.4 1 1 0 1 1 1 1 Malate synthase Reprolysin PF01421.19 KDO32368.1 - 0.012 15.5 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease HpcH_HpaI PF03328.14 KDO32368.1 - 0.094 11.8 0.0 0.26 10.4 0.0 1.7 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family SNF2_N PF00176.23 KDO32369.1 - 9.3e-65 218.6 0.0 2.3e-64 217.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO32369.1 - 1.2e-19 70.7 0.0 3.9e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO32369.1 - 3.7e-11 43.3 0.0 2.3e-10 40.8 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KDO32369.1 - 2.3e-10 40.1 0.2 1.4e-09 37.5 0.2 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KDO32369.1 - 3.9e-05 23.5 0.0 0.00012 21.8 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KDO32369.1 - 0.068 12.0 0.0 0.35 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Acetyltransf_10 PF13673.7 KDO32370.1 - 2.2e-15 56.7 0.0 2.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO32370.1 - 9.5e-12 45.2 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO32370.1 - 4.8e-09 36.5 0.0 6.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO32370.1 - 9e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KDO32370.1 - 0.017 15.2 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KDO32370.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.27 KDO32371.1 - 1.1e-62 211.1 0.0 1.6e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KDO32371.1 - 6.3e-24 84.1 0.0 6.1e-23 80.9 0.0 2.6 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 KDO32371.1 - 6.2e-19 67.8 0.0 1.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KDO32371.1 - 1e-12 48.0 0.0 2.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KDO32371.1 - 1.6e-11 44.4 0.0 3.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO32371.1 - 0.0013 18.8 0.1 0.0029 17.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KDO32374.1 - 0.019 15.2 1.6 0.028 14.6 1.6 1.3 1 1 0 1 1 1 0 AAA domain DUF3589 PF12141.8 KDO32374.1 - 0.055 12.0 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Beta-mannosyltransferases Glyphos_transf PF04464.14 KDO32374.1 - 0.077 12.0 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase LRR_8 PF13855.6 KDO32375.1 - 0.023 14.4 5.2 3.8 7.3 1.9 4.1 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KDO32375.1 - 0.12 13.0 6.9 0.35 11.6 0.2 4.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO32375.1 - 0.45 11.0 8.7 3.7 8.1 0.4 4.7 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) PDZ_6 PF17820.1 KDO32379.1 - 2.6e-08 33.6 0.0 0.0089 15.9 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 KDO32379.1 - 1.6e-07 31.5 0.0 0.011 16.0 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KDO32379.1 - 0.0096 16.2 0.0 1 9.7 0.0 3.1 3 0 0 3 3 3 1 PDZ domain CN_hydrolase PF00795.22 KDO32380.1 - 7.5e-62 209.0 0.1 8.5e-62 208.8 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAM2 PF07145.15 KDO32382.1 - 0.019 14.6 0.0 0.055 13.2 0.0 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Methyltransf_11 PF08241.12 KDO32383.1 - 6.4e-13 49.2 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO32383.1 - 4.9e-11 43.2 0.0 1.1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO32383.1 - 3.9e-10 39.8 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO32383.1 - 7.2e-08 33.1 0.0 2.3e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO32383.1 - 2.3e-06 27.5 0.0 6.7e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO32383.1 - 2.3e-05 23.9 0.0 5.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Clathrin_H_link PF13838.6 KDO32383.1 - 0.019 14.8 1.0 0.041 13.8 0.4 1.8 2 0 0 2 2 2 0 Clathrin-H-link vATP-synt_AC39 PF01992.16 KDO32384.1 - 6.5e-104 348.0 0.0 7.4e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Tup_N PF08581.10 KDO32385.1 - 0.27 11.5 0.4 0.27 11.5 0.4 2.8 2 1 1 3 3 3 0 Tup N-terminal LURAP PF14854.6 KDO32385.1 - 0.49 10.4 7.3 0.062 13.3 2.7 2.0 2 1 0 2 2 2 0 Leucine rich adaptor protein SlyX PF04102.12 KDO32385.1 - 1.8 9.2 15.7 0.38 11.4 1.3 3.4 2 1 1 3 3 3 0 SlyX ZapB PF06005.12 KDO32385.1 - 1.9 9.0 12.9 5.9 7.4 0.1 3.1 3 0 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 KDO32385.1 - 4.1 7.2 10.3 13 5.6 0.3 3.2 3 0 0 3 3 3 0 Septum formation initiator Exonuc_VII_L PF02601.15 KDO32385.1 - 7 6.1 10.5 14 5.2 10.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Csm1_N PF18504.1 KDO32385.1 - 9.4 6.7 8.3 1.3 9.4 0.1 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Uso1_p115_C PF04871.13 KDO32385.1 - 9.8 6.6 11.8 4.5 7.7 0.2 2.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PH PF00169.29 KDO32386.1 - 9.9e-40 135.3 0.0 3.2e-06 27.6 0.0 8.3 7 1 1 8 8 8 8 PH domain PH_8 PF15409.6 KDO32386.1 - 1.6e-05 25.1 0.4 0.22 11.8 0.0 5.0 6 0 0 6 6 6 2 Pleckstrin homology domain MRI PF15325.6 KDO32387.1 - 0.021 15.9 0.5 0.026 15.6 0.5 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection E1-E2_ATPase PF00122.20 KDO32388.1 - 2.2e-21 76.2 0.9 5.7e-21 74.9 0.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KDO32388.1 - 5.7e-12 46.4 0.8 2.9e-06 27.7 0.1 3.3 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO32388.1 - 8.9e-05 22.5 0.0 0.00025 21.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KDO32388.1 - 0.08 12.6 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO32388.1 - 0.15 11.7 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MtrA PF04208.14 KDO32388.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF3106 PF11304.8 KDO32388.1 - 0.55 10.7 4.9 3.5 8.2 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Trypsin PF00089.26 KDO32389.1 - 0.00038 20.3 0.8 0.00057 19.7 0.2 1.6 1 1 1 2 2 2 1 Trypsin TMEM154 PF15102.6 KDO32389.1 - 0.0028 17.6 4.9 0.0054 16.6 4.9 1.4 1 0 0 1 1 1 1 TMEM154 protein family Mucin PF01456.17 KDO32389.1 - 1.7 8.7 46.0 6.8 6.7 45.9 2.0 1 1 0 1 1 1 0 Mucin-like glycoprotein Hamartin PF04388.12 KDO32389.1 - 6.3 5.3 8.3 7.4 5.1 8.3 1.1 1 0 0 1 1 1 0 Hamartin protein Hus1 PF04005.12 KDO32390.1 - 4.2e-48 163.9 0.1 5.2e-48 163.6 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF4354 PF14263.6 KDO32390.1 - 0.13 12.1 0.0 3.9 7.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4354) Tom37 PF10568.9 KDO32391.1 - 1.5e-23 83.5 0.0 2.3e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KDO32391.1 - 9.6e-16 58.4 0.0 1.7e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KDO32391.1 - 3.5e-13 49.1 0.1 1.3e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO32391.1 - 3.8e-06 26.8 0.1 1.1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Myb_DNA-binding PF00249.31 KDO32392.1 - 5.2e-35 119.4 10.7 1.1e-12 47.9 0.9 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO32392.1 - 1.1e-32 112.1 3.3 2.2e-16 59.8 0.1 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 KDO32392.1 - 0.00025 21.0 0.0 0.15 12.1 0.0 2.5 2 1 0 2 2 2 2 SLIDE Rap1_C PF11626.8 KDO32392.1 - 0.16 12.1 2.4 1.8 8.7 1.2 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KDO32392.1 - 3.7 8.0 10.4 11 6.4 0.5 3.4 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain PH PF00169.29 KDO32393.1 - 0.017 15.6 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 PH domain zf-C3HC4_3 PF13920.6 KDO32394.1 - 1.6e-09 37.4 10.3 3.4e-09 36.4 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO32394.1 - 5.9e-09 36.1 15.2 1.3e-08 35.1 15.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO32394.1 - 9.1e-08 31.8 14.0 1.8e-07 30.9 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO32394.1 - 4.3e-06 26.5 13.7 7.6e-06 25.7 13.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO32394.1 - 1.7e-05 24.8 11.8 3.6e-05 23.7 11.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO32394.1 - 1.7e-05 24.7 12.4 3.2e-05 23.8 12.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO32394.1 - 6.8e-05 22.6 10.6 0.00013 21.7 10.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO32394.1 - 7.3e-05 23.0 9.2 0.00015 21.9 9.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KDO32394.1 - 0.0004 20.5 13.4 0.00096 19.3 13.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KDO32394.1 - 0.0045 16.8 6.7 0.01 15.7 6.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KDO32394.1 - 0.029 14.4 4.2 0.059 13.4 4.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KDO32394.1 - 0.52 10.1 7.9 1.3 8.9 7.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KDO32394.1 - 0.59 10.0 6.2 1.2 9.0 6.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit 2OG-FeII_Oxy_3 PF13640.6 KDO32395.1 - 2.8e-08 34.5 0.2 6.4e-08 33.4 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 KDO32396.1 - 4.4e-45 153.6 0.1 7.3e-45 152.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO32396.1 - 6.8e-19 68.3 0.0 5.2e-17 62.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO32396.1 - 5.4e-09 36.3 0.0 9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 KDO32396.1 - 0.13 12.5 0.3 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Ras PF00071.22 KDO32398.1 - 5.1e-62 208.2 0.2 6e-62 208.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO32398.1 - 2.6e-33 114.8 0.1 5.2e-33 113.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO32398.1 - 2.7e-13 49.8 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO32398.1 - 2.7e-05 24.2 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO32398.1 - 0.00013 21.9 0.2 0.33 10.8 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO32398.1 - 0.00037 20.1 0.0 0.0023 17.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO32398.1 - 0.00051 19.5 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KDO32398.1 - 0.03 14.6 0.1 0.18 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KDO32398.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.9 KDO32398.1 - 0.069 12.3 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 COPI_assoc PF08507.10 KDO32399.1 - 2.5e-13 50.2 4.1 3.5e-13 49.8 4.1 1.1 1 0 0 1 1 1 1 COPI associated protein Tup_N PF08581.10 KDO32400.1 - 0.0075 16.6 3.7 0.48 10.8 0.2 2.5 2 0 0 2 2 2 2 Tup N-terminal Peptidase_C12 PF01088.21 KDO32401.1 - 5.7e-42 143.9 0.0 6.4e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SURF2 PF05477.11 KDO32402.1 - 1.4e-28 100.2 14.5 1.2e-27 97.2 14.5 2.0 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 KDO32402.1 - 0.00051 19.5 13.6 0.00062 19.2 13.6 1.1 1 0 0 1 1 1 1 BUD22 Spt5_N PF11942.8 KDO32402.1 - 0.096 13.7 1.4 0.096 13.7 1.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-C2H2_2 PF12756.7 KDO32402.1 - 0.1 12.9 0.1 1.5 9.2 0.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) NOA36 PF06524.12 KDO32402.1 - 0.17 11.2 8.7 0.28 10.5 8.7 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3767 PF12597.8 KDO32403.1 - 6.7e-15 54.7 0.1 7.8e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Myb_DNA-bind_7 PF15963.5 KDO32404.1 - 2.6e-23 81.7 0.1 6.7e-23 80.4 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KDO32404.1 - 0.01 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain CcdA PF07362.12 KDO32404.1 - 0.079 13.4 0.4 0.22 12.0 0.4 1.7 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA KH_1 PF00013.29 KDO32405.1 - 3.6e-59 196.5 12.8 3.3e-18 65.2 0.7 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KDO32405.1 - 3.2e-10 39.7 10.5 0.041 13.7 0.0 4.5 3 1 1 4 4 4 3 KH domain KH_4 PF13083.6 KDO32405.1 - 3.4e-10 39.6 9.8 0.0029 17.4 0.2 4.7 4 1 1 5 5 5 3 KH domain KH_5 PF13184.6 KDO32405.1 - 2.2e-06 27.7 2.4 3.4 7.8 0.0 4.5 4 0 0 4 4 4 2 NusA-like KH domain SLS PF14611.6 KDO32405.1 - 0.14 12.0 0.1 22 4.8 0.0 3.0 2 2 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator Spt20 PF12090.8 KDO32405.1 - 0.62 9.6 9.6 1 8.9 9.6 1.3 1 0 0 1 1 1 0 Spt20 family Gln-synt_C PF00120.24 KDO32406.1 - 2.1e-18 66.5 0.0 6.3e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KDO32406.1 - 1.1e-13 50.7 0.0 2.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain AATase PF07247.12 KDO32407.1 - 0.085 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase DHHC PF01529.20 KDO32408.1 - 3.6e-21 75.7 7.9 3.6e-21 75.7 7.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3808 PF10300.9 KDO32409.1 - 1.3e-06 27.4 0.2 8.7e-05 21.4 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) PDZ_6 PF17820.1 KDO32409.1 - 0.0059 16.4 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain ACT_7 PF13840.6 KDO32410.1 - 1.2e-25 89.1 0.1 1.2e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KDO32410.1 - 0.00072 19.3 0.0 0.05 13.4 0.0 2.4 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain DUF2228 PF10228.9 KDO32412.1 - 0.14 11.9 3.7 0.24 11.1 3.7 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) TPR_MLP1_2 PF07926.12 KDO32412.1 - 0.31 11.1 22.7 0.79 9.8 22.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MMM1 PF10296.9 KDO32412.1 - 0.95 8.4 6.1 1.6 7.7 6.1 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 FliD_N PF02465.18 KDO32412.1 - 2.2 9.0 8.4 1.9 9.2 5.7 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Phage_GPO PF05929.11 KDO32412.1 - 5.7 6.5 16.0 0.47 10.0 11.2 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Bcl-2_BAD PF10514.9 KDO32414.1 - 0.0088 16.5 3.6 0.0088 16.5 3.6 1.8 2 0 0 2 2 2 1 Pro-apoptotic Bcl-2 protein, BAD zf-RING_4 PF14570.6 KDO32414.1 - 0.011 15.6 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain vATP-synt_AC39 PF01992.16 KDO32414.1 - 0.015 14.8 1.9 0.043 13.3 1.8 1.8 1 1 1 2 2 2 0 ATP synthase (C/AC39) subunit Pro_isomerase PF00160.21 KDO32415.1 - 1.7e-24 86.9 0.3 2.7e-24 86.3 0.3 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PRP38 PF03371.15 KDO32416.1 - 2.6e-51 173.9 0.1 4.8e-51 173.1 0.1 1.4 1 0 0 1 1 1 1 PRP38 family SMN PF06003.12 KDO32416.1 - 0.00025 20.4 0.9 0.00044 19.6 0.1 1.6 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) DUF4454 PF14628.6 KDO32416.1 - 0.04 13.7 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) CDC45 PF02724.14 KDO32416.1 - 3.5 5.8 9.9 5.1 5.3 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 KDO32416.1 - 4.6 6.8 26.3 7.3 6.1 26.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dus PF01207.17 KDO32417.1 - 9.4e-71 238.4 0.0 1.2e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KDO32417.1 - 0.0089 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 KDO32417.1 - 0.02 14.4 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 KDO32417.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 KDO32417.1 - 0.041 13.3 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase FMN_dh PF01070.18 KDO32417.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 KDO32417.1 - 0.2 10.8 0.0 6.7 5.8 0.0 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase IFT46_B_C PF12317.8 KDO32418.1 - 3.9e-92 307.8 1.7 5.7e-92 307.2 1.7 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF515 PF04415.12 KDO32418.1 - 0.03 12.7 0.6 0.054 11.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4460 PF14687.6 KDO32419.1 - 0.028 14.4 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) RelA_SpoT PF04607.17 KDO32419.1 - 0.036 14.3 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins Ion_trans_2 PF07885.16 KDO32420.1 - 2.9e-06 27.1 1.7 9.6e-06 25.5 1.7 1.8 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 KDO32420.1 - 0.00054 19.9 1.0 0.0012 18.8 1.0 1.5 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Yip1 PF04893.17 KDO32420.1 - 2.6 7.7 11.7 1.9 8.2 1.0 2.4 2 0 0 2 2 2 0 Yip1 domain Arm PF00514.23 KDO32421.1 - 2.1e-22 78.4 43.9 0.00028 20.8 0.1 14.0 15 0 0 15 15 15 8 Armadillo/beta-catenin-like repeat DUF383 PF04063.14 KDO32421.1 - 0.00019 21.1 6.8 1 9.0 0.1 5.7 4 2 2 6 6 6 2 Domain of unknown function (DUF383) HEAT_2 PF13646.6 KDO32421.1 - 0.0021 18.4 13.9 0.25 11.7 0.1 6.9 7 1 1 8 8 8 2 HEAT repeats V-ATPase_H_N PF03224.14 KDO32421.1 - 0.0029 17.0 13.7 0.08 12.2 0.1 5.0 1 1 1 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 KDO32421.1 - 0.0032 17.0 10.6 6.3 6.2 0.1 5.7 3 3 1 6 6 6 3 Armadillo-like HEAT_EZ PF13513.6 KDO32421.1 - 4.7 7.8 23.1 6 7.5 0.5 8.1 8 0 0 8 8 8 0 HEAT-like repeat fn3 PF00041.21 KDO32422.1 - 8.4e-10 38.9 0.2 0.00082 19.7 0.0 4.4 2 2 0 2 2 2 2 Fibronectin type III domain PA PF02225.22 KDO32422.1 - 3.9e-07 30.0 0.0 9.5e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 PA domain Glutaredoxin PF00462.24 KDO32423.1 - 4.4e-10 39.6 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin PT PF04886.12 KDO32423.1 - 0.026 14.1 30.5 0.1 12.1 30.5 2.1 1 1 0 1 1 1 0 PT repeat HAD_SAK_1 PF10307.9 KDO32426.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Anoctamin PF04547.12 KDO32427.1 - 8.2e-86 288.6 0.8 9.7e-86 288.4 0.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PIP5K PF01504.18 KDO32428.1 - 1.3e-72 244.4 0.0 1.7e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_1 PF00001.21 KDO32428.1 - 1.4e-05 24.6 14.2 0.00031 20.2 14.2 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KDO32428.1 - 3.5e-05 23.2 13.5 7e-05 22.2 13.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.9 KDO32428.1 - 7.8 5.8 13.8 21 4.4 13.8 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx NDK PF00334.19 KDO32431.1 - 2e-11 44.1 0.0 3.9e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Myb_DNA-bind_6 PF13921.6 KDO32431.1 - 0.013 15.7 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Enolase_C PF00113.22 KDO32432.1 - 9.6e-148 491.2 0.1 1.2e-147 490.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KDO32432.1 - 6.6e-58 194.5 0.0 1.2e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KDO32432.1 - 9.1e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KDO32432.1 - 3.2e-06 26.5 0.1 6.7e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus WD40 PF00400.32 KDO32433.1 - 0.0005 20.8 0.1 13 6.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat WD-3 PF09765.9 KDO32433.1 - 0.047 13.0 0.2 0.078 12.3 0.2 1.2 1 0 0 1 1 1 0 WD-repeat region FAM220 PF15487.6 KDO32433.1 - 0.059 13.0 0.4 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 FAM220 family Acetyltransf_1 PF00583.25 KDO32434.1 - 3.8e-20 72.3 0.0 4.9e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO32434.1 - 6.6e-13 48.7 0.0 7.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO32434.1 - 2.9e-12 46.8 0.1 4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO32434.1 - 4.4e-10 39.4 0.1 6.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KDO32434.1 - 1.8e-07 30.9 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KDO32434.1 - 0.0001 23.0 0.0 0.00012 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KDO32434.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KDO32434.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KDO32434.1 - 0.025 14.6 0.0 0.088 12.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MCM PF00493.23 KDO32435.1 - 2.5e-104 347.3 0.2 4.2e-104 346.5 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KDO32435.1 - 1.7e-31 108.7 1.1 3.7e-31 107.6 1.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KDO32435.1 - 8.4e-22 77.4 1.7 2.2e-21 76.1 1.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KDO32435.1 - 2.9e-16 59.9 0.4 1.6e-15 57.6 0.1 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KDO32435.1 - 1.4e-07 31.2 0.2 6.7e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO32435.1 - 4.8e-06 26.6 0.0 1.9e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KDO32435.1 - 1.2e-05 25.2 0.0 4.4e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO32435.1 - 0.0072 16.7 0.2 0.05 14.0 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_lid_2 PF17863.1 KDO32435.1 - 0.055 13.3 1.2 0.16 11.9 0.2 2.3 2 0 0 2 2 2 0 AAA lid domain Mg_chelatase_C PF13335.6 KDO32435.1 - 0.063 13.9 0.8 0.32 11.6 0.8 2.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 KDO32435.1 - 0.076 12.7 0.1 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KDO32435.1 - 0.095 13.1 0.2 0.38 11.2 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DENN PF02141.21 KDO32436.1 - 5.4e-30 104.7 1.8 1.1e-29 103.7 1.8 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 KDO32436.1 - 1.1e-12 48.3 0.8 7.7e-07 29.4 0.1 3.3 3 0 0 3 3 3 2 Regulator of G protein signaling domain dDENN PF03455.19 KDO32436.1 - 0.0097 15.9 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 1 dDENN domain ParcG PF10274.9 KDO32437.1 - 5e-61 206.0 0.0 6.5e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein APG5 PF04106.12 KDO32438.1 - 2.9e-46 157.9 0.4 4.2e-46 157.4 0.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Aa_trans PF01490.18 KDO32439.1 - 1.6e-40 139.1 21.2 2e-40 138.8 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UQ_con PF00179.26 KDO32440.1 - 8.2e-43 145.4 0.0 9.9e-43 145.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KDO32440.1 - 2.1e-11 43.5 0.0 4.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 KDO32440.1 - 2.5e-05 24.0 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KDO32440.1 - 0.0024 18.2 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain CUE PF02845.16 KDO32440.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 CUE domain Cpn60_TCP1 PF00118.24 KDO32441.1 - 3.2e-90 303.1 12.1 6.9e-90 302.0 12.1 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Anoctamin PF04547.12 KDO32444.1 - 3.8e-64 217.2 25.9 5.3e-64 216.7 25.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel FliT PF05400.13 KDO32444.1 - 0.034 15.0 0.6 0.079 13.8 0.6 1.6 1 0 0 1 1 1 0 Flagellar protein FliT EF-hand_7 PF13499.6 KDO32444.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Myc_N PF01056.18 KDO32445.1 - 1.5 8.7 10.8 0.06 13.2 3.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region FHA PF00498.26 KDO32446.1 - 4.1e-16 59.1 0.0 7.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 KDO32446.1 - 2.3e-09 36.9 10.7 5.5e-09 35.7 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO32446.1 - 4.3e-09 36.6 10.7 1.2e-08 35.1 10.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO32446.1 - 5.7e-09 35.7 9.8 1.4e-08 34.5 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO32446.1 - 6.1e-08 32.4 5.5 1.4e-07 31.3 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO32446.1 - 5.9e-07 29.4 8.5 1.6e-06 28.0 8.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KDO32446.1 - 6.5e-07 29.4 12.7 6.5e-07 29.4 12.7 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO32446.1 - 6.3e-06 26.0 8.8 1.6e-05 24.8 8.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO32446.1 - 0.004 17.0 12.1 0.0066 16.3 10.3 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO32446.1 - 0.0089 16.3 11.9 0.033 14.5 11.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.5 KDO32446.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DEP PF00610.21 KDO32446.1 - 0.14 12.3 0.2 0.67 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-RING_4 PF14570.6 KDO32446.1 - 0.84 9.5 6.8 4.5 7.1 6.8 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain mit_SMPDase PF14724.6 KDO32447.1 - 2.5e-17 62.2 1.9 1.1e-10 40.2 0.0 2.7 2 1 1 3 3 3 2 Mitochondrial-associated sphingomyelin phosphodiesterase Bromodomain PF00439.25 KDO32448.1 - 2.2e-22 78.9 0.0 7.5e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 Bromodomain TFIIA PF03153.13 KDO32448.1 - 1.9e-05 24.9 18.4 1.9e-05 24.9 18.4 3.9 4 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit DDT PF02791.17 KDO32448.1 - 0.00039 20.7 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 KDO32448.1 - 0.0088 15.9 0.7 0.025 14.5 0.7 1.8 1 0 0 1 1 1 1 PHD-finger DUF4681 PF15732.5 KDO32449.1 - 0.02 15.2 0.3 0.045 14.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) TMEM215 PF15746.5 KDO32449.1 - 0.026 14.0 1.2 0.038 13.4 0.4 1.6 1 1 0 1 1 1 0 TMEM215 family SpoIIE PF07228.12 KDO32450.1 - 8.6e-17 61.7 0.0 1e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CBS PF00571.28 KDO32450.1 - 7e-16 58.4 0.7 2e-07 31.3 0.2 2.7 2 0 0 2 2 2 2 CBS domain PP2C PF00481.21 KDO32450.1 - 5.3e-06 26.2 0.2 0.031 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KDO32450.1 - 0.00032 20.4 1.2 0.0011 18.7 0.1 2.3 2 2 0 2 2 2 1 Protein phosphatase 2C ApbE PF02424.15 KDO32450.1 - 0.011 15.2 1.2 0.036 13.6 0.0 2.3 3 0 0 3 3 3 0 ApbE family SCP2_2 PF13530.6 KDO32451.1 - 0.026 14.9 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain NUDIX PF00293.28 KDO32452.1 - 2e-11 44.1 0.1 2.6e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KDO32453.1 - 1.5e-10 41.2 0.0 1.8e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L27 PF01016.19 KDO32456.1 - 1.3e-35 121.3 0.8 1.9e-35 120.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein PS_Dcarbxylase PF02666.15 KDO32457.1 - 1.9e-60 203.8 0.0 2.4e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Arf PF00025.21 KDO32458.1 - 6.4e-26 90.9 0.0 2.6e-21 75.8 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO32458.1 - 0.00022 20.8 0.0 0.0051 16.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KDO32458.1 - 0.00028 21.1 0.1 0.23 11.7 0.1 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KDO32458.1 - 0.002 18.1 0.1 0.0058 16.6 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO32458.1 - 0.0021 18.5 0.0 0.0054 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KDO32458.1 - 0.0074 15.9 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KDO32458.1 - 0.014 14.6 0.0 1.8 7.7 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit DLIC PF05783.11 KDO32458.1 - 0.022 13.6 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 KDO32458.1 - 0.025 14.9 0.1 0.082 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KDO32458.1 - 0.044 13.9 0.0 0.33 11.0 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KDO32458.1 - 0.05 13.0 0.0 5.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.22 KDO32458.1 - 0.061 12.9 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.9 KDO32458.1 - 0.076 12.8 0.1 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 KDO32458.1 - 0.088 12.2 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KDO32458.1 - 0.1 12.6 0.2 0.36 10.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KDO32458.1 - 0.12 11.5 0.1 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 SRP54 PF00448.22 KDO32458.1 - 0.19 11.3 0.1 0.65 9.6 0.1 1.8 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Pkr1 PF08636.10 KDO32459.1 - 2.9e-11 43.3 2.9 3.3e-11 43.1 2.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Peptidase_M14 PF00246.24 KDO32460.1 - 3.2e-43 148.6 0.0 5.8e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_16 PF00722.21 KDO32460.1 - 0.00045 19.7 0.1 0.0008 18.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Hydrolase_4 PF12146.8 KDO32461.1 - 7e-15 54.9 0.2 1.9e-14 53.5 0.2 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO32461.1 - 6.5e-12 45.6 0.2 1.1e-09 38.3 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO32461.1 - 2.5e-08 34.8 0.4 4.4e-08 34.0 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KDO32461.1 - 0.0022 17.4 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S15 PF02129.18 KDO32461.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KDO32461.1 - 0.036 13.6 0.0 0.69 9.4 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family PH PF00169.29 KDO32462.1 - 8.6e-56 186.9 0.0 1.4e-07 31.9 0.0 11.2 12 0 0 12 12 12 9 PH domain PH_11 PF15413.6 KDO32462.1 - 8.1e-09 35.9 7.2 13 6.3 0.0 10.3 10 1 0 10 10 10 2 Pleckstrin homology domain PH_13 PF16652.5 KDO32462.1 - 0.00018 21.4 1.7 2.8 7.7 0.0 5.9 7 0 0 7 7 7 1 Pleckstrin homology domain PH_4 PF15404.6 KDO32462.1 - 0.002 17.9 2.7 30 4.3 0.0 6.3 7 0 0 7 7 7 0 Pleckstrin homology domain PH_9 PF15410.6 KDO32462.1 - 0.0051 17.2 7.2 67 3.9 0.0 8.1 7 3 0 7 7 7 0 Pleckstrin homology domain Csm1_N PF18504.1 KDO32462.1 - 3.3 8.1 6.5 0.88 10.0 1.0 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain LMBR1 PF04791.16 KDO32462.1 - 3.9 6.3 5.4 7 5.4 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ERCC4 PF02732.15 KDO32463.1 - 5.1e-06 26.8 0.0 7.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 KDO32463.1 - 0.13 12.9 0.0 0.37 11.4 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain MA3 PF02847.17 KDO32464.1 - 1.7e-29 102.1 0.3 5.4e-20 71.5 0.1 2.4 2 0 0 2 2 2 2 MA3 domain LRR_6 PF13516.6 KDO32465.1 - 5.3e-16 57.2 9.7 0.015 15.3 0.0 7.6 7 0 0 7 7 7 5 Leucine Rich repeat EF-hand_1 PF00036.32 KDO32465.1 - 2.8e-06 26.5 0.1 0.015 14.8 0.0 2.7 2 0 0 2 2 2 2 EF hand DUF4476 PF14771.6 KDO32465.1 - 4.9e-06 26.8 0.1 0.00029 21.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) EF-hand_7 PF13499.6 KDO32465.1 - 0.0002 21.8 0.1 0.00051 20.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO32465.1 - 0.00026 20.7 0.1 0.53 10.4 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 KDO32465.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KDO32465.1 - 0.031 13.8 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KDO32465.1 - 0.034 14.0 0.1 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair LRR_1 PF00560.33 KDO32465.1 - 0.51 11.1 7.2 66 4.7 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO32465.1 - 2.2 8.8 12.4 15 6.2 2.6 4.5 2 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO32465.1 - 8.2 6.3 12.7 22 4.9 3.9 4.9 3 2 1 4 4 4 0 Leucine rich repeat Glyco_hydro_72 PF03198.14 KDO32466.1 - 2.6e-45 155.0 0.3 3.7e-45 154.6 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KDO32466.1 - 0.00027 20.5 0.0 0.026 14.0 0.0 2.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Complex1_LYR PF05347.15 KDO32468.1 - 5.1e-13 48.9 1.0 6.6e-13 48.5 1.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KDO32468.1 - 0.00015 22.5 0.3 0.00017 22.3 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KDO32468.1 - 0.0062 17.1 0.3 0.0074 16.9 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like WW PF00397.26 KDO32469.1 - 5.5e-11 42.4 11.3 9.6e-08 32.0 2.6 2.6 2 0 0 2 2 2 2 WW domain zf-B_box PF00643.24 KDO32469.1 - 6.3 7.0 36.3 2.1 8.6 7.5 3.5 3 0 0 3 3 3 0 B-box zinc finger Glyco_hydro_72 PF03198.14 KDO32470.1 - 1.9e-45 155.5 0.1 2.7e-45 155.0 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Ebp2 PF05890.12 KDO32471.1 - 3.4e-65 220.3 32.9 4.3e-65 219.9 32.9 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 UPF0524 PF15823.5 KDO32471.1 - 1.4 8.3 4.8 0.18 11.2 0.2 1.8 2 0 0 2 2 2 0 UPF0524 of C3orf70 KBP_C PF12309.8 KDO32471.1 - 3.4 7.1 15.8 0.067 12.7 7.9 2.1 2 1 1 3 3 3 0 KIF-1 binding protein C terminal TPR_MLP1_2 PF07926.12 KDO32473.1 - 0.081 13.0 2.5 0.18 11.9 2.5 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Flu_C_NS2 PF03555.14 KDO32473.1 - 0.16 12.1 0.7 12 6.2 0.1 2.2 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) ALIX_LYPXL_bnd PF13949.6 KDO32473.1 - 0.21 10.8 3.2 0.27 10.5 3.1 1.3 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV dCache_3 PF14827.6 KDO32473.1 - 0.28 10.8 1.6 0.34 10.5 0.4 1.7 2 1 0 2 2 2 0 Double sensory domain of two-component sensor kinase Kinesin PF00225.23 KDO32474.1 - 9.9e-91 304.1 0.0 1.6e-90 303.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO32474.1 - 3.7e-21 75.6 0.1 7.6e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding Prominin PF05478.11 KDO32474.1 - 0.027 12.4 5.1 0.045 11.7 5.1 1.2 1 0 0 1 1 1 0 Prominin Wtap PF17098.5 KDO32474.1 - 0.031 14.2 12.1 0.51 10.3 4.4 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family Mrpl_C PF18502.1 KDO32474.1 - 0.093 13.0 2.3 0.27 11.5 2.3 1.9 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF4407 PF14362.6 KDO32474.1 - 0.28 10.5 10.8 0.47 9.8 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SWI-SNF_Ssr4 PF08549.10 KDO32474.1 - 0.32 9.6 14.1 0.24 10.0 1.6 2.3 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) PhoH PF02562.16 KDO32474.1 - 0.51 9.7 2.7 5.9 6.3 0.1 2.9 3 0 0 3 3 3 0 PhoH-like protein Jnk-SapK_ap_N PF09744.9 KDO32474.1 - 1.5 9.0 18.9 80 3.4 18.9 2.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA PF00004.29 KDO32476.1 - 8.9e-10 39.1 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KDO32476.1 - 2.2e-05 24.5 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KDO32476.1 - 2.3e-05 24.9 0.0 5.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO32476.1 - 0.00011 22.5 0.0 0.001 19.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KDO32476.1 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RFC1 PF08519.12 KDO32476.1 - 0.0007 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA_30 PF13604.6 KDO32476.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO32476.1 - 0.0027 17.9 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO32476.1 - 0.0035 16.9 0.0 0.01 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KDO32476.1 - 0.0043 17.5 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KDO32476.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO32476.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KDO32476.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_assoc_2 PF16193.5 KDO32476.1 - 0.014 15.7 0.0 0.041 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_23 PF13476.6 KDO32476.1 - 0.017 15.6 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO32476.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO32476.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KDO32476.1 - 0.095 11.7 0.4 0.46 9.5 0.0 2.3 2 1 1 3 3 3 0 Type II/IV secretion system protein ABC_tran PF00005.27 KDO32476.1 - 0.11 13.0 0.0 0.37 11.3 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 KDO32476.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KDO32476.1 - 0.17 11.3 0.1 0.51 9.8 0.0 1.8 1 1 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KDO32476.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KDO32476.1 - 0.19 12.0 0.5 0.82 10.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain WW PF00397.26 KDO32477.1 - 8.5e-06 25.8 4.1 8.5e-06 25.8 4.1 2.3 2 0 0 2 2 2 1 WW domain SWIRM-assoc_3 PF16498.5 KDO32477.1 - 0.0012 19.1 0.1 0.0063 16.7 0.0 2.2 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal Band_7 PF01145.25 KDO32478.1 - 4.4e-23 82.2 3.8 4.4e-23 82.2 3.8 2.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family DivIVA PF05103.13 KDO32478.1 - 0.14 12.2 6.4 0.28 11.3 6.4 1.5 1 0 0 1 1 1 0 DivIVA protein WD40 PF00400.32 KDO32479.1 - 3.8e-45 151.0 14.2 1.5e-08 35.1 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO32479.1 - 2e-05 24.8 1.5 0.52 10.6 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KDO32479.1 - 2.5e-05 23.2 0.0 0.082 11.6 0.0 4.1 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 KDO32479.1 - 0.0032 16.2 7.3 1.7 7.2 0.1 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KDO32479.1 - 0.043 13.1 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain FAD_binding_3 PF01494.19 KDO32480.1 - 1.9e-07 30.7 0.2 2.1e-06 27.2 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KDO32480.1 - 2.3e-07 30.7 0.2 5.5e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO32480.1 - 9.9e-06 25.0 0.0 2.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KDO32480.1 - 0.00025 20.4 0.1 0.0006 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KDO32480.1 - 0.00035 19.9 0.0 0.33 10.6 0.0 2.6 2 0 0 2 2 2 2 EF hand NAD_binding_8 PF13450.6 KDO32480.1 - 0.0005 20.2 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KDO32480.1 - 0.0012 18.0 0.1 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KDO32480.1 - 0.0015 17.3 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.6 KDO32480.1 - 0.0016 18.9 0.0 0.0046 17.4 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding EF-hand_6 PF13405.6 KDO32480.1 - 0.0023 17.7 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Pyr_redox PF00070.27 KDO32480.1 - 0.0024 18.4 0.1 0.0069 16.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KDO32480.1 - 0.0026 17.1 0.0 0.0058 15.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KDO32480.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KDO32480.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EF-hand_7 PF13499.6 KDO32480.1 - 0.012 16.0 0.0 0.051 14.0 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain pair CUE PF02845.16 KDO32480.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain Thi4 PF01946.17 KDO32480.1 - 0.026 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KDO32480.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KDO32480.1 - 0.061 12.4 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KDO32480.1 - 0.071 12.5 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NHL PF01436.21 KDO32481.1 - 1.3e-15 56.5 17.7 0.00013 21.8 0.1 5.8 6 0 0 6 6 6 5 NHL repeat DUF5128 PF17170.4 KDO32481.1 - 0.028 13.6 0.0 4 6.5 0.0 2.2 1 1 0 2 2 2 0 6-bladed beta-propeller F-box PF00646.33 KDO32481.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain DAGK_acc PF00609.19 KDO32483.1 - 1.1e-43 149.3 0.0 1.8e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KDO32483.1 - 1.4e-25 89.4 0.0 2.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KDO32483.1 - 2.2e-08 33.9 31.5 6.8e-07 29.1 9.3 3.0 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KDO32483.1 - 0.00089 19.1 19.0 0.0051 16.7 1.8 2.6 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 KDO32483.1 - 0.022 15.0 12.8 0.045 14.1 0.6 2.6 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 KDO32483.1 - 0.045 13.9 12.8 0.99 9.6 2.4 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 KDO32483.1 - 5.5 7.1 13.0 16 5.7 1.6 2.9 1 1 0 2 2 2 0 PHD-finger DAGK_acc PF00609.19 KDO32484.1 - 1.2e-33 116.7 0.0 1.9e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KDO32484.1 - 3.7e-22 78.3 0.0 6.3e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KDO32484.1 - 6.2e-17 61.2 13.5 2.5e-09 36.9 5.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KDO32484.1 - 0.0021 18.2 6.9 0.043 13.9 1.2 2.5 2 0 0 2 2 2 2 KIAA1045 RING finger PHD PF00628.29 KDO32484.1 - 0.0042 16.9 15.9 0.05 13.5 3.3 2.6 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 KDO32484.1 - 0.0054 17.0 0.3 0.0054 17.0 0.3 3.1 2 1 1 3 3 3 1 C1 domain PHD_2 PF13831.6 KDO32484.1 - 0.49 10.0 7.0 4.7 6.8 0.5 2.9 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 KDO32484.1 - 0.82 9.8 11.6 0.074 13.2 1.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) PCRF PF03462.18 KDO32485.1 - 6.6e-48 163.1 0.0 1.1e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KDO32485.1 - 1.6e-40 137.6 0.1 3.6e-40 136.5 0.1 1.5 1 0 0 1 1 1 1 RF-1 domain LRR_6 PF13516.6 KDO32486.1 - 2.1e-21 74.1 14.4 0.0036 17.2 0.0 8.6 8 0 0 8 8 8 7 Leucine Rich repeat LRR_8 PF13855.6 KDO32486.1 - 3.9e-05 23.3 12.9 5.3 6.9 0.0 7.2 4 2 2 7 7 7 4 Leucine rich repeat LRR_1 PF00560.33 KDO32486.1 - 0.00012 22.1 1.4 1.2e+02 3.8 0.1 7.1 6 2 0 6 6 6 0 Leucine Rich Repeat MORN PF02493.20 KDO32487.1 - 8.5e-21 72.6 21.0 3.2e-06 26.7 0.8 5.1 5 0 0 5 5 5 4 MORN repeat DUF3048_C PF17479.2 KDO32487.1 - 0.59 10.5 5.1 8.5 6.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain ECR1_N PF14382.6 KDO32487.1 - 4.1 7.3 9.6 31 4.5 0.7 4.0 3 1 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Ctr PF04145.15 KDO32488.1 - 1.9e-19 70.7 0.2 3e-19 70.1 0.2 1.2 1 0 0 1 1 1 1 Ctr copper transporter family zf-ribbon_3 PF13248.6 KDO32488.1 - 0.36 10.3 3.8 15 5.2 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain bZIP_2 PF07716.15 KDO32489.1 - 0.0037 17.3 7.4 0.012 15.6 1.8 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KDO32489.1 - 0.054 13.6 4.6 11 6.3 0.0 2.4 2 1 0 2 2 2 0 bZIP transcription factor Csm1_N PF18504.1 KDO32489.1 - 0.073 13.4 1.5 8.1 6.9 0.2 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 KDO32489.1 - 0.083 12.7 5.5 2.2 8.1 1.4 2.2 2 0 0 2 2 2 0 Septum formation initiator MerR-DNA-bind PF09278.11 KDO32489.1 - 0.26 11.8 11.2 1.6 9.3 3.3 3.3 1 1 1 2 2 2 0 MerR, DNA binding DUF4140 PF13600.6 KDO32489.1 - 2.1 8.8 6.0 3.8 8.0 0.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NEMO PF11577.8 KDO32490.1 - 0.013 15.5 6.6 0.069 13.2 0.1 2.5 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO HR1 PF02185.16 KDO32490.1 - 0.017 15.2 4.7 0.017 15.2 4.7 1.9 2 0 0 2 2 2 0 Hr1 repeat ABC_tran_CTD PF16326.5 KDO32490.1 - 0.018 15.2 2.1 0.018 15.2 2.1 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pox_A_type_inc PF04508.12 KDO32490.1 - 0.03 14.2 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CCDC-167 PF15188.6 KDO32490.1 - 0.041 14.2 4.0 0.041 14.2 4.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 bZIP_2 PF07716.15 KDO32490.1 - 0.081 13.0 14.5 0.47 10.6 7.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF4140 PF13600.6 KDO32490.1 - 0.26 11.8 7.0 0.29 11.6 2.7 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 KDO32490.1 - 0.51 8.9 1.8 0.64 8.6 1.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KDO32490.1 - 0.85 10.3 6.4 15 6.3 6.2 2.1 1 1 0 1 1 1 0 Initiation control protein YabA HAUS6_N PF14661.6 KDO32490.1 - 4.8 6.7 9.2 12 5.4 9.0 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DEAD PF00270.29 KDO32492.1 - 1.2e-47 162.0 0.1 6.8e-47 159.5 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO32492.1 - 3.3e-26 91.8 0.0 2.3e-25 89.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO32492.1 - 3.9e-07 30.2 0.0 6.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KDO32492.1 - 0.0038 16.9 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KDO32492.1 - 0.0093 16.2 0.1 0.029 14.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain LSM PF01423.22 KDO32493.1 - 3.1e-19 68.4 0.0 3.4e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO32493.1 - 1e-05 25.6 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Beach PF02138.18 KDO32494.1 - 3e-112 374.5 0.0 4e-112 374.1 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KDO32494.1 - 7e-09 35.7 0.0 4.4e-06 26.7 0.0 3.3 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KDO32494.1 - 9.5e-08 32.6 8.8 0.00066 20.4 0.1 6.2 5 2 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO32494.1 - 1.1e-06 28.8 0.0 0.034 14.5 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 KDO32494.1 - 9.7e-05 22.2 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 KDO32494.1 - 0.0061 16.9 0.0 0.054 13.8 0.0 2.4 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain TIR_2 PF13676.6 KDO32494.1 - 0.047 14.3 0.1 24 5.6 0.0 3.2 3 0 0 3 3 3 0 TIR domain DEC-1_N PF04625.13 KDO32494.1 - 0.064 12.3 4.3 0.1 11.6 4.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cytochrom_D1 PF02239.16 KDO32494.1 - 0.075 11.6 0.1 0.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.11 KDO32494.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split WD40_like PF17005.5 KDO32494.1 - 0.14 11.4 0.1 0.86 8.9 0.0 2.2 3 0 0 3 3 3 0 WD40-like domain YbfN PF13982.6 KDO32495.1 - 0.0075 16.5 1.3 0.016 15.5 0.2 1.9 2 0 0 2 2 2 1 YbfN-like lipoprotein KxDL PF10241.9 KDO32495.1 - 0.016 15.5 4.2 0.016 15.5 4.2 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein Metal_resist PF13801.6 KDO32495.1 - 0.12 12.6 0.7 0.42 10.8 0.7 1.8 1 1 0 1 1 1 0 Heavy-metal resistance Spc7 PF08317.11 KDO32495.1 - 0.12 11.2 16.1 0.14 11.0 16.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KDO32495.1 - 0.14 12.0 8.6 0.17 11.7 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4715 PF15835.5 KDO32495.1 - 0.18 11.9 3.9 0.29 11.2 2.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) APG6_N PF17675.1 KDO32495.1 - 0.21 12.1 13.7 0.11 13.0 11.0 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 KDO32495.1 - 0.62 10.1 5.2 0.47 10.5 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 KDO32495.1 - 2.5 7.6 13.0 0.92 9.0 3.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 KDO32495.1 - 5.8 6.1 8.8 6.7 5.9 8.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 KDO32496.1 - 1.4e-63 214.7 0.0 2.2e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32496.1 - 2.6e-31 108.9 0.0 3.3e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO32496.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO32496.1 - 1.2e-05 24.3 0.0 2.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO32496.1 - 0.0084 16.1 0.8 0.79 9.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KDO32496.1 - 0.047 13.3 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KDO32496.1 - 0.065 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 KDO32497.1 - 1.5e-47 161.8 0.0 2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Neurensin PF14927.6 KDO32498.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Neurensin TIG PF01833.24 KDO32499.1 - 9.5e-09 35.2 0.0 0.00068 19.7 0.0 4.0 3 0 0 3 3 3 2 IPT/TIG domain TIG_plexin PF17960.1 KDO32499.1 - 0.09 12.8 1.2 12 6.0 0.0 2.8 3 0 0 3 3 3 0 TIG domain Aa_trans PF01490.18 KDO32500.1 - 1.3e-48 165.8 29.2 1.5e-48 165.5 29.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ANAPC_CDC26 PF10471.9 KDO32501.1 - 0.011 16.5 1.2 0.016 16.0 1.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 zf-RING_2 PF13639.6 KDO32502.1 - 1e-09 38.6 8.0 1.8e-09 37.7 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO32502.1 - 2.6e-08 33.6 6.8 4.8e-08 32.7 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO32502.1 - 3.6e-07 30.4 8.6 1.2e-06 28.7 8.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO32502.1 - 2.9e-06 27.0 10.0 6.6e-06 25.9 9.6 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO32502.1 - 6.6e-06 25.9 8.3 1.6e-05 24.7 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO32502.1 - 0.0003 20.8 5.3 0.0003 20.8 5.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KDO32502.1 - 0.0017 18.4 5.7 0.0017 18.4 5.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO32502.1 - 0.002 18.0 9.8 0.0075 16.1 9.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KDO32502.1 - 0.0042 17.0 8.7 0.011 15.7 8.5 1.8 1 1 1 2 2 2 1 zinc-RING finger domain TerY_C PF15616.6 KDO32502.1 - 0.023 14.8 1.2 0.039 14.1 1.2 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_11 PF17123.5 KDO32502.1 - 0.044 13.5 7.7 0.032 14.0 5.3 2.0 2 0 0 2 2 2 0 RING-like zinc finger Menin PF05053.13 KDO32502.1 - 0.11 10.8 5.8 0.15 10.4 5.8 1.1 1 0 0 1 1 1 0 Menin zf-RING-like PF08746.11 KDO32502.1 - 0.14 12.5 8.8 0.037 14.3 4.5 2.1 2 0 0 2 2 2 0 RING-like domain DNA_ligase_ZBD PF03119.16 KDO32502.1 - 0.26 11.4 6.5 0.83 9.7 0.3 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_ribbon_17 PF17120.5 KDO32502.1 - 0.37 10.5 3.2 0.67 9.6 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zn-ribbon_8 PF09723.10 KDO32502.1 - 1.1 9.5 7.0 18 5.5 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 KDO32502.1 - 1.2 9.0 6.0 2.4 8.0 5.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KDO32502.1 - 1.4 8.9 5.0 3.3 7.7 5.0 1.7 1 0 0 1 1 1 0 PHD-finger Neur_chan_memb PF02932.16 KDO32502.1 - 4.6 7.2 5.7 9.8 6.2 5.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WW PF00397.26 KDO32503.1 - 9.7e-24 83.2 11.5 8.1e-08 32.2 0.0 3.3 3 0 0 3 3 3 3 WW domain Glyco_hyd_101C PF17451.2 KDO32503.1 - 0.0035 17.6 7.0 2.4 8.4 0.0 3.5 1 1 2 3 3 3 3 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 KDO32503.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.3 1 1 2 3 3 3 0 PQQ enzyme repeat PepSY PF03413.19 KDO32503.1 - 0.051 14.1 0.2 0.15 12.7 0.2 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Metal_hydrol PF10118.9 KDO32503.1 - 0.15 11.8 8.8 0.19 11.4 8.8 1.1 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase Tcp11 PF05794.13 KDO32504.1 - 0.15 11.1 0.7 1.8 7.6 0.1 2.0 2 0 0 2 2 2 0 T-complex protein 11 DUF733 PF05306.11 KDO32505.1 - 0.016 15.5 0.0 0.56 10.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF733) NDK PF00334.19 KDO32506.1 - 3.1e-11 43.4 0.0 2.2e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Chi-conotoxin PF16981.5 KDO32506.1 - 0.075 13.3 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily DNA_primase_S PF01896.19 KDO32506.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit ATP-gua_Ptrans PF00217.19 KDO32508.1 - 7e-133 440.7 0.0 3.4e-76 255.4 0.0 3.1 2 1 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KDO32508.1 - 4.9e-62 206.3 0.1 3.7e-30 104.1 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain DUF3420 PF11900.8 KDO32508.1 - 0.0017 18.4 0.1 0.78 9.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3420) XFP_N PF09364.10 KDO32508.1 - 0.13 11.1 0.0 2.3 6.9 0.0 2.1 2 0 0 2 2 2 0 XFP N-terminal domain Wzy_C PF04932.15 KDO32508.1 - 0.15 11.7 0.0 19 4.8 0.0 2.6 3 0 0 3 3 3 0 O-Antigen ligase Tho2 PF11262.8 KDO32509.1 - 4e-78 262.7 0.2 4e-78 262.7 0.2 2.9 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 KDO32509.1 - 1.3e-60 205.8 0.1 2.5e-38 132.1 0.0 5.1 4 2 0 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 KDO32509.1 - 4.2e-17 62.0 0.0 2.5e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit AIG1 PF04548.16 KDO32509.1 - 0.057 12.7 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 AIG1 family A_deaminase PF00962.22 KDO32510.1 - 1.4e-114 382.9 0.0 2.4e-114 382.1 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Myb_DNA-binding PF00249.31 KDO32512.1 - 1.3e-42 143.8 7.7 6.2e-16 58.3 0.1 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO32512.1 - 7.4e-33 112.6 3.1 3.1e-14 53.0 0.0 3.2 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 KDO32512.1 - 6.1e-05 23.0 0.7 0.049 13.7 0.4 2.6 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 KDO32512.1 - 0.0018 18.3 0.0 8.2 6.5 0.0 3.1 1 1 2 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 KDO32512.1 - 0.0056 16.9 0.1 0.08 13.1 0.0 2.2 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KDO32512.1 - 0.023 14.6 0.0 3.9 7.5 0.0 2.7 1 1 2 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KDO32512.1 - 0.15 12.5 5.2 21 5.6 0.4 3.3 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KDO32512.1 - 0.17 12.2 4.1 3.6 8.0 0.4 3.5 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UPF0176_N PF17773.1 KDO32513.1 - 1.1e-19 70.6 0.0 1.9e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KDO32513.1 - 1.3e-12 48.2 0.0 3.7e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Rhodanese_C PF12368.8 KDO32513.1 - 1.7e-12 47.5 6.4 3.2e-12 46.6 6.4 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Acyltransferase PF01553.21 KDO32517.1 - 7.9e-20 70.8 0.0 1.3e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KDO32517.1 - 0.00023 21.2 0.0 0.00067 19.7 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase C-terminus Porin_OmpG PF09381.10 KDO32517.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) Macoilin PF09726.9 KDO32518.1 - 0.14 10.7 2.0 0.19 10.2 2.0 1.2 1 0 0 1 1 1 0 Macoilin family LRR_4 PF12799.7 KDO32520.1 - 0.93 10.0 5.2 10 6.7 2.9 2.9 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) zf-C3HC4_3 PF13920.6 KDO32521.1 - 1e-10 41.3 15.5 1.6e-10 40.6 15.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO32521.1 - 8.5e-06 25.5 15.4 1.4e-05 24.8 15.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO32521.1 - 0.0087 16.4 19.4 0.015 15.6 19.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KDO32521.1 - 0.32 11.0 16.3 0.54 10.3 16.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PH PF00169.29 KDO32522.1 - 1.7e-15 57.4 0.0 2.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 PH domain Sigma70_ner PF04546.13 KDO32522.1 - 0.0025 17.7 0.7 0.0025 17.7 0.7 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region HTH_29 PF13551.6 KDO32522.1 - 0.16 12.0 0.1 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix PH_8 PF15409.6 KDO32522.1 - 0.29 11.4 1.5 39 4.6 0.2 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain SDA1 PF05285.12 KDO32522.1 - 0.43 10.0 17.2 0.33 10.4 6.6 2.1 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 KDO32522.1 - 9 6.3 18.1 1.2 9.1 6.4 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FH2 PF02181.23 KDO32523.1 - 6.3e-78 262.5 0.0 9e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 KDO32523.1 - 5.8e-63 211.9 26.7 7.7e-13 49.1 2.3 7.3 7 0 0 7 7 7 6 Subunit CCDC53 of WASH complex MOZART1 PF12554.8 KDO32523.1 - 0.00023 20.9 0.0 5.9 6.8 0.0 4.5 4 0 0 4 4 4 1 Mitotic-spindle organizing gamma-tubulin ring associated zf-HC5HC2H_2 PF13832.6 KDO32523.1 - 0.005 17.0 2.1 0.012 15.7 2.1 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KDO32523.1 - 0.056 13.3 11.0 0.14 12.1 11.0 1.7 1 1 0 1 1 1 0 PHD-finger DSPc PF00782.20 KDO32523.1 - 0.1 12.4 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PIN_5 PF08745.11 KDO32523.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 PINc domain ribonuclease zf-RING_9 PF13901.6 KDO32523.1 - 0.41 10.6 4.2 0.97 9.4 4.2 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KDO32523.1 - 0.44 10.7 6.2 0.97 9.6 6.2 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-PHD-like PF15446.6 KDO32523.1 - 0.89 9.2 8.5 0.39 10.3 5.2 2.0 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Fer4_9 PF13187.6 KDO32523.1 - 1.1 9.5 6.8 2.5 8.3 6.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain PHD_2 PF13831.6 KDO32523.1 - 2 8.0 8.7 0.13 11.8 2.5 2.1 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KDO32523.1 - 2.5 8.3 6.2 7.2 6.8 6.2 1.8 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KDO32523.1 - 5.7 6.9 10.2 7.5 6.5 5.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FancD2 PF14631.6 KDO32524.1 - 8.9e-96 321.7 10.7 4.8e-47 160.2 0.9 3.1 2 1 1 3 3 3 3 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 KDO32524.1 - 9.1e-06 26.1 0.0 8e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 FANCI solenoid 2 Ricin_B_lectin PF00652.22 KDO32526.1 - 7.9e-05 22.9 0.3 0.093 13.0 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain GTP_EFTU PF00009.27 KDO32527.1 - 3.3e-43 147.5 0.0 5.3e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KDO32527.1 - 2.7e-22 79.2 0.0 6.9e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KDO32527.1 - 4.8e-06 26.6 0.1 0.0026 17.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KDO32527.1 - 2.4e-05 24.7 0.3 5.9e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Usp PF00582.26 KDO32527.1 - 0.043 14.3 0.2 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 Universal stress protein family HBS1_N PF08938.10 KDO32527.1 - 0.49 10.7 7.6 0.5 10.7 5.6 2.0 2 1 0 2 2 2 0 HBS1 N-terminus RRS1 PF04939.12 KDO32528.1 - 1.7e-55 187.3 8.8 1.7e-55 187.3 8.8 2.5 2 1 1 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) SelK_SelG PF10961.8 KDO32529.1 - 7.6e-20 71.3 5.5 9e-20 71.1 5.5 1.1 1 0 0 1 1 1 1 Selenoprotein SelK_SelG SET PF00856.28 KDO32531.1 - 9.8e-05 22.8 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 2 SET domain Rubis-subs-bind PF09273.11 KDO32531.1 - 0.00077 20.2 0.9 0.036 14.8 0.1 2.4 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding EF1_GNE PF00736.19 KDO32532.1 - 6.1e-30 103.3 3.2 6.1e-30 103.3 3.2 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Ribosomal_60s PF00428.19 KDO32532.1 - 0.0067 17.0 3.1 0.0067 17.0 3.1 2.8 3 1 0 3 3 3 1 60s Acidic ribosomal protein EF-1_beta_acid PF10587.9 KDO32532.1 - 0.036 14.5 10.2 0.036 14.5 10.2 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region VIR_N PF15912.5 KDO32532.1 - 0.12 11.9 2.9 0.17 11.4 2.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal eIF3_subunit PF08597.10 KDO32532.1 - 0.27 11.1 16.0 0.4 10.6 16.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 KDO32532.1 - 3.2 8.2 10.8 0.11 12.9 5.0 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF5 PF04855.12 KDO32533.1 - 2.5e-35 122.4 0.1 6.2e-32 111.3 0.1 2.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HMG_box PF00505.19 KDO32533.1 - 1.4e-13 51.1 1.5 2.8e-13 50.1 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KDO32533.1 - 1.1e-06 29.1 0.8 2.7e-06 27.9 0.8 1.7 1 0 0 1 1 1 1 HMG-box domain HTH_31 PF13560.6 KDO32533.1 - 0.00013 22.2 0.1 0.00031 21.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KDO32533.1 - 0.0016 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 KDO32533.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KDO32533.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Med22 PF06179.12 KDO32534.1 - 4.7e-19 68.5 2.9 5.6e-19 68.3 2.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Apolipoprotein PF01442.18 KDO32534.1 - 0.0011 18.8 0.5 0.0013 18.6 0.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Syntaxin_2 PF14523.6 KDO32534.1 - 0.038 14.4 2.5 0.18 12.2 1.9 1.9 1 1 1 2 2 2 0 Syntaxin-like protein GxGYxYP_N PF16216.5 KDO32534.1 - 0.058 13.6 0.2 0.069 13.3 0.2 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal DotU PF09850.9 KDO32534.1 - 0.061 13.0 0.2 0.26 11.0 0.0 1.9 1 1 1 2 2 2 0 Type VI secretion system protein DotU BORCS7 PF16088.5 KDO32534.1 - 0.078 13.2 1.7 0.11 12.7 1.7 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 YtxH PF12732.7 KDO32534.1 - 0.14 12.7 1.9 1.3 9.6 1.9 2.1 1 1 0 1 1 1 0 YtxH-like protein DER1 PF04511.15 KDO32535.1 - 4.8e-61 206.0 13.1 5.5e-61 205.8 13.1 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 KDO32535.1 - 0.072 12.9 1.4 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Oleosin FmiP_Thoc5 PF09766.9 KDO32537.1 - 1.8e-65 221.6 0.0 2.3e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 ABC_tran_CTD PF16326.5 KDO32537.1 - 0.08 13.2 0.3 0.08 13.2 0.3 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Cortex-I_coil PF09304.10 KDO32537.1 - 2.6 8.3 6.9 0.88 9.8 1.8 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil TMEM18 PF14770.6 KDO32538.1 - 7.2e-37 126.0 2.4 8.7e-37 125.7 2.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 PrgI PF12666.7 KDO32538.1 - 2.2 9.0 5.3 18 6.1 5.3 2.0 1 1 0 1 1 1 0 PrgI family protein NAPRTase_C PF17956.1 KDO32539.1 - 3e-30 104.9 0.0 5.6e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 KDO32539.1 - 6.2e-29 100.9 0.8 2.9e-28 98.7 0.1 2.6 3 1 0 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KDO32539.1 - 1.6e-07 31.2 0.0 2.6e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family AAA_6 PF12774.7 KDO32540.1 - 9.7e-121 402.7 0.0 9.5e-120 399.5 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO32540.1 - 2.2e-98 330.0 3.1 3.8e-98 329.2 0.1 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO32540.1 - 4.8e-52 176.9 0.1 2.8e-51 174.4 0.0 2.4 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 KDO32540.1 - 1.7e-36 125.2 0.0 4.3e-22 78.6 0.0 5.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KDO32540.1 - 3.2e-27 95.2 0.8 4.3e-23 81.7 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region DHC_N1 PF08385.12 KDO32540.1 - 1.2e-22 80.3 0.0 4.3e-22 78.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 KDO32540.1 - 2.2e-09 36.8 4.0 5.3e-09 35.6 4.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 KDO32540.1 - 1.7e-08 35.0 13.9 0.097 13.0 0.0 8.4 9 0 0 9 9 9 2 AAA ATPase domain AAA PF00004.29 KDO32540.1 - 1e-07 32.4 0.2 0.25 11.7 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO32540.1 - 9.5e-07 29.2 4.2 2.2 8.6 0.0 6.3 6 0 0 6 6 6 1 AAA domain RsgA_GTPase PF03193.16 KDO32540.1 - 2.7e-05 24.1 0.1 0.024 14.5 0.0 3.8 4 0 0 4 4 4 1 RsgA GTPase IstB_IS21 PF01695.17 KDO32540.1 - 0.00018 21.3 0.4 1 9.1 0.0 3.7 3 0 0 3 3 3 2 IstB-like ATP binding protein ABC_tran PF00005.27 KDO32540.1 - 0.00036 21.1 0.2 0.12 12.9 0.0 3.7 3 0 0 3 3 2 1 ABC transporter AAA_18 PF13238.6 KDO32540.1 - 0.00038 21.0 0.0 0.26 11.8 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KDO32540.1 - 0.00044 20.4 0.0 1.2 9.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KDO32540.1 - 0.0005 19.9 0.1 0.11 12.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KDO32540.1 - 0.0012 18.8 1.1 3.8 7.4 0.0 5.2 6 0 0 6 6 5 1 Rad17 P-loop domain AAA_30 PF13604.6 KDO32540.1 - 0.0017 18.1 1.4 0.36 10.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KDO32540.1 - 0.0019 18.6 0.1 3.4 8.1 0.0 4.1 4 0 0 4 4 4 1 RNA helicase AAA_29 PF13555.6 KDO32540.1 - 0.0028 17.3 0.0 0.25 11.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KDO32540.1 - 0.0065 16.7 0.4 1.2 9.3 0.0 4.0 5 0 0 5 5 4 1 AAA domain ATPase_2 PF01637.18 KDO32540.1 - 0.0086 16.0 0.1 0.63 9.9 0.0 3.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KDO32540.1 - 0.01 15.6 0.0 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KDO32540.1 - 0.031 13.9 0.0 12 5.4 0.0 3.8 4 0 0 4 4 3 0 AAA domain HAP1_N PF04849.13 KDO32540.1 - 0.056 12.6 5.1 0.076 12.2 3.5 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF1866 PF08952.11 KDO32540.1 - 0.094 12.6 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Golgin_A5 PF09787.9 KDO32540.1 - 0.11 12.0 6.6 0.37 10.2 6.6 1.9 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fuseless PF15993.5 KDO32540.1 - 0.12 11.6 0.2 0.26 10.4 0.2 1.5 1 0 0 1 1 1 0 Fuseless GrpE PF01025.19 KDO32540.1 - 0.28 10.8 6.3 0.094 12.4 2.3 2.3 2 0 0 2 2 2 0 GrpE Spc7 PF08317.11 KDO32540.1 - 0.55 9.1 14.4 1.5 7.7 6.4 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_23 PF13476.6 KDO32540.1 - 0.77 10.2 7.0 27 5.2 2.1 3.6 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 KDO32540.1 - 0.79 9.4 3.3 1.3 8.7 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF948 PF06103.11 KDO32540.1 - 6.8 7.0 6.2 8.5 6.7 1.3 3.9 4 1 0 4 4 2 0 Bacterial protein of unknown function (DUF948) Na_Ca_ex PF01699.24 KDO32541.1 - 7.2e-39 133.2 35.9 9.5e-23 80.8 16.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2627 PF11118.8 KDO32541.1 - 0.49 11.0 2.7 15 6.3 1.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) Na_Ca_ex PF01699.24 KDO32542.1 - 5.4e-40 136.8 32.4 2.4e-22 79.5 15.0 3.3 3 1 0 3 3 3 3 Sodium/calcium exchanger protein DUF2615 PF11027.8 KDO32542.1 - 0.056 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Cadherin_C_2 PF16492.5 KDO32542.1 - 0.18 12.6 1.6 0.4 11.5 0.0 2.4 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Cupin_8 PF13621.6 KDO32543.1 - 2.5e-14 53.6 0.0 6.2e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KDO32543.1 - 1.2e-06 28.9 0.0 9.2e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KDO32543.1 - 4.2e-06 26.5 0.1 1.3e-05 24.8 0.1 1.8 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 KDO32543.1 - 3.2e-05 23.6 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KDO32543.1 - 0.0076 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AraC-like ligand binding domain DNase_II PF03265.15 KDO32544.1 - 1.4e-16 60.7 0.0 1.8e-15 57.1 0.0 2.5 1 1 0 1 1 1 1 Deoxyribonuclease II Ribosomal_S27 PF01599.19 KDO32544.1 - 0.38 11.0 2.7 0.83 9.9 2.7 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a RRM_1 PF00076.22 KDO32545.1 - 1.1e-49 166.1 0.0 5e-19 67.9 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KDO32545.1 - 4e-05 23.6 0.0 0.0096 16.0 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 KDO32545.1 - 0.006 16.6 0.0 0.31 11.1 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KDO32545.1 - 0.032 14.4 0.0 7.8 6.7 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif DUF3343 PF11823.8 KDO32545.1 - 0.084 12.3 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Ank_4 PF13637.6 KDO32546.1 - 5.2e-19 68.4 9.4 4.4e-09 36.7 0.5 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO32546.1 - 1.4e-17 64.0 2.9 3.6e-11 43.5 0.5 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) EF-hand_1 PF00036.32 KDO32546.1 - 2e-10 39.4 0.4 0.00021 20.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO32546.1 - 3.7e-10 40.1 0.3 6.4e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair Ank_3 PF13606.6 KDO32546.1 - 2.5e-09 36.6 2.5 0.0015 18.9 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO32546.1 - 1.1e-07 32.0 2.3 0.00057 20.1 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 KDO32546.1 - 7.7e-07 28.6 0.3 0.024 14.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain Ank PF00023.30 KDO32546.1 - 2.7e-06 27.6 11.5 0.0024 18.2 0.1 4.5 5 1 0 5 5 4 2 Ankyrin repeat EF-hand_8 PF13833.6 KDO32546.1 - 0.00031 20.5 0.6 0.00083 19.1 0.7 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO32546.1 - 0.008 15.6 2.5 0.51 9.9 1.5 2.5 2 0 0 2 2 2 1 EF hand Copper-bind PF00127.20 KDO32546.1 - 0.0091 16.4 0.2 1.1 9.8 0.1 2.4 1 1 1 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Mur_ligase PF01225.25 KDO32546.1 - 0.015 15.7 0.1 6.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Ribosomal_L19e PF01280.20 KDO32547.1 - 0.19 11.8 0.5 0.3 11.2 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L19e Cyt-b5 PF00173.28 KDO32548.1 - 1.3e-07 31.7 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain PX PF00787.24 KDO32549.1 - 0.0096 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Hydrolase_4 PF12146.8 KDO32550.1 - 3.7e-19 68.9 0.0 6.7e-12 45.2 0.0 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KDO32550.1 - 0.019 15.1 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Sec3_C PF09763.9 KDO32550.1 - 0.17 10.2 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 PX PF00787.24 KDO32551.1 - 4.4e-05 23.4 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PX domain Herpes_UL33 PF03581.13 KDO32551.1 - 0.078 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL33-like protein Ribosomal_L15e PF00827.17 KDO32551.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L15 Anth_synt_I_N PF04715.13 KDO32553.1 - 0.089 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region PIP5K PF01504.18 KDO32556.1 - 3e-63 213.6 0.0 4.4e-61 206.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.18 KDO32557.1 - 3.8e-60 203.4 0.0 3.1e-48 164.4 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase EXS PF03124.14 KDO32558.1 - 2.9e-79 266.8 20.0 4.9e-79 266.1 20.0 1.3 1 0 0 1 1 1 1 EXS family LpxB PF02684.15 KDO32559.1 - 3.8e-67 226.7 0.3 9.5e-37 126.7 0.0 3.0 2 1 0 2 2 2 2 Lipid-A-disaccharide synthetase Glyco_trans_1_4 PF13692.6 KDO32559.1 - 0.0011 19.4 1.7 0.074 13.5 0.2 3.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 KDO32559.1 - 0.013 14.3 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 KDO32559.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF354) PI3_PI4_kinase PF00454.27 KDO32560.1 - 2.2e-24 86.6 0.4 5.1e-15 56.0 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 KDO32560.1 - 1.6e-17 63.3 4.8 1.6e-17 63.3 4.8 2.7 2 1 0 2 2 2 1 FYVE zinc finger PI3Ka PF00613.20 KDO32560.1 - 7.2e-09 35.3 0.1 8e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KDO32560.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) FYVE_2 PF02318.16 KDO32560.1 - 0.0092 16.2 0.8 0.0092 16.2 0.8 2.8 3 0 0 3 3 3 1 FYVE-type zinc finger PhnA_Zn_Ribbon PF08274.12 KDO32560.1 - 0.082 12.9 0.5 2.1 8.4 0.0 2.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF2757 PF10955.8 KDO32560.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2757) DCP1 PF06058.13 KDO32561.1 - 3.9e-34 117.1 0.1 5.3e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KDO32561.1 - 0.00093 18.4 0.1 0.0019 17.5 0.1 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus Spt20 PF12090.8 KDO32561.1 - 0.13 11.9 4.0 0.18 11.4 4.0 1.3 1 0 0 1 1 1 0 Spt20 family ORC6 PF05460.13 KDO32561.1 - 0.2 10.9 4.7 0.25 10.6 4.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 KDO32561.1 - 3.3 6.3 6.3 4.1 6.0 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 KDO32561.1 - 3.8 7.9 9.6 23 5.3 9.6 2.0 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Exo_endo_phos PF03372.23 KDO32562.1 - 7.1e-06 25.7 0.1 2.1e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Chor_lyase PF04345.13 KDO32562.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Chorismate lyase HhH-GPD PF00730.25 KDO32563.1 - 1.9e-17 63.6 0.0 3.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ammonium_transp PF00909.21 KDO32563.1 - 5.6e-14 51.6 0.0 1.3e-13 50.4 0.0 1.7 1 1 1 2 2 2 1 Ammonium Transporter Family HHH PF00633.23 KDO32563.1 - 2.5e-08 33.4 0.3 7.6e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KDO32563.1 - 0.023 15.3 0.1 0.27 11.8 0.0 2.4 2 1 1 3 3 3 0 Helix-hairpin-helix domain DUF2400 PF09674.10 KDO32563.1 - 0.12 12.4 0.1 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) PAP2_C PF14360.6 KDO32565.1 - 1.9e-17 63.5 13.7 1.9e-17 63.5 13.7 3.2 3 1 1 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KDO32565.1 - 3.4e-06 26.9 5.1 3.4e-06 26.9 5.1 2.7 3 0 0 3 3 3 1 PAP2 superfamily LRR_8 PF13855.6 KDO32566.1 - 1e-19 70.1 22.7 7.6e-09 35.2 3.5 4.9 1 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KDO32566.1 - 2e-16 59.8 14.3 0.00032 21.0 0.2 5.4 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO32566.1 - 1.3e-12 46.4 22.5 0.43 11.3 0.1 9.2 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.6 KDO32566.1 - 4.5e-08 32.5 15.6 0.87 9.8 0.0 7.4 8 0 0 8 8 8 5 Leucine Rich repeat DUF3682 PF12446.8 KDO32569.1 - 0.071 13.6 1.6 0.094 13.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ank_4 PF13637.6 KDO32570.1 - 4.3e-16 59.0 3.4 4.8e-05 23.8 0.0 5.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO32570.1 - 2.1e-14 53.8 0.0 1.2e-06 29.0 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO32570.1 - 2.3e-13 50.1 4.3 3.8e-05 23.9 0.2 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32570.1 - 1.3e-09 37.5 1.4 0.0036 17.7 0.1 4.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KDO32570.1 - 5.4e-08 32.9 8.9 0.0046 17.3 0.1 5.1 4 0 0 4 4 4 2 Ankyrin repeat LysM PF01476.20 KDO32573.1 - 2.2e-33 114.1 0.0 8.4e-11 41.8 0.0 4.3 4 0 0 4 4 4 4 LysM domain DUF3071 PF11268.8 KDO32573.1 - 0.068 13.2 0.1 22 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3071) LRR_4 PF12799.7 KDO32574.1 - 6.8e-16 58.1 10.8 6.4e-07 29.6 0.9 4.7 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO32574.1 - 1e-14 54.0 8.9 1.3e-05 24.9 0.9 4.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KDO32574.1 - 1.3e-09 37.9 2.5 2e-08 33.9 1.5 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KDO32574.1 - 6e-06 25.9 2.8 4.4 7.6 0.0 5.6 6 0 0 6 6 5 2 Leucine Rich repeat CENP-F_leu_zip PF10473.9 KDO32574.1 - 0.00013 22.0 66.3 0.067 13.2 13.9 7.0 1 1 5 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KDO32574.1 - 0.011 15.7 9.8 0.011 15.7 9.8 7.5 6 2 2 8 8 8 0 TolA binding protein trimerisation LRR_1 PF00560.33 KDO32574.1 - 0.057 14.0 6.4 62 4.7 0.0 5.5 4 2 0 4 4 4 0 Leucine Rich Repeat Fez1 PF06818.15 KDO32574.1 - 0.089 13.2 65.2 0.59 10.6 4.3 5.2 1 1 4 5 5 5 0 Fez1 HSBP1 PF06825.12 KDO32574.1 - 0.16 11.8 15.2 0.54 10.2 0.1 4.4 4 0 0 4 4 3 0 Heat shock factor binding protein 1 FPP PF05911.11 KDO32574.1 - 0.23 9.6 60.7 1 7.5 48.8 2.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Baculo_PEP_C PF04513.12 KDO32574.1 - 0.26 11.3 37.8 1.7 8.7 2.1 5.8 2 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin PF00261.20 KDO32574.1 - 0.54 9.6 75.9 0.65 9.3 24.3 5.6 2 1 2 5 5 5 0 Tropomyosin Filament PF00038.21 KDO32574.1 - 0.92 9.0 75.1 0.45 10.1 19.0 5.9 2 1 3 5 5 4 0 Intermediate filament protein GTP_EFTU PF00009.27 KDO32575.1 - 1.1e-45 155.6 0.0 1.6e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KDO32575.1 - 2e-32 112.4 10.0 5e-32 111.1 10.0 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KDO32575.1 - 6.7e-24 84.0 0.0 1.5e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KDO32575.1 - 1.4e-23 82.7 0.0 6e-23 80.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KDO32575.1 - 2.1e-06 28.0 0.1 4.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KDO32575.1 - 1e-05 25.5 0.2 2e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KDO32575.1 - 2.8e-05 24.1 2.0 6.9e-05 22.9 0.0 2.5 3 0 0 3 3 3 1 Elongation Factor G, domain II Roc PF08477.13 KDO32575.1 - 0.0032 17.7 0.0 2.5 8.3 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KDO32575.1 - 0.008 15.6 0.1 0.32 10.4 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KDO32575.1 - 0.09 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein HTH_DeoR PF08220.12 KDO32576.1 - 0.42 10.4 4.6 40 4.1 0.0 3.9 4 0 0 4 4 4 0 DeoR-like helix-turn-helix domain CTP_transf_1 PF01148.20 KDO32577.1 - 0.019 14.8 0.7 0.019 14.8 0.7 2.4 2 0 0 2 2 2 0 Cytidylyltransferase family TetR_C_21 PF17926.1 KDO32577.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3792 PF12670.7 KDO32577.1 - 8.6 6.6 11.3 0.47 10.6 3.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Pkinase PF00069.25 KDO32578.1 - 3e-57 194.0 0.0 3.5e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32578.1 - 2.2e-32 112.4 0.0 2.7e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO32578.1 - 4.6e-10 39.3 0.0 6.3e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KDO32578.1 - 4.6e-05 22.9 0.2 7.1e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO32578.1 - 5.1e-05 23.3 0.3 0.00015 21.8 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO32578.1 - 0.0013 17.6 0.0 0.0015 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KDO32578.1 - 0.0053 16.4 0.0 0.076 12.6 0.0 2.2 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO32578.1 - 0.0053 15.7 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KDO32578.1 - 0.11 11.5 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Filament PF00038.21 KDO32579.1 - 0.0012 18.5 9.7 0.0012 18.5 9.7 3.3 3 1 1 4 4 4 2 Intermediate filament protein Ank_2 PF12796.7 KDO32580.1 - 8.4e-25 87.2 0.1 4.7e-12 46.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32580.1 - 7.7e-22 77.4 0.1 2.2e-08 34.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO32580.1 - 6.6e-19 67.4 0.8 9e-05 22.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KDO32580.1 - 1.3e-18 65.2 0.1 9.9e-05 22.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KDO32580.1 - 2.1e-17 62.9 0.5 6.6e-08 32.7 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Vps36-NZF-N PF16988.5 KDO32580.1 - 0.093 12.1 2.9 0.25 10.8 2.9 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Methyltransf_23 PF13489.6 KDO32581.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO32581.1 - 0.0061 16.4 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO32581.1 - 0.037 14.7 0.0 0.078 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TB2_DP1_HVA22 PF03134.19 KDO32582.1 - 5.4e-29 100.0 3.8 8.5e-29 99.3 3.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TRAPP PF04051.16 KDO32583.1 - 5.1e-36 123.6 0.0 5.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SIMPL PF04402.14 KDO32583.1 - 0.15 12.5 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ribosomal_S9 PF00380.19 KDO32584.1 - 0.22 12.1 0.1 0.46 11.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DHHC PF01529.20 KDO32586.1 - 1.5e-29 102.8 10.3 1.5e-29 102.8 10.3 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Aa_trans PF01490.18 KDO32587.1 - 8.7e-49 166.3 18.3 8.7e-49 166.3 18.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.27 KDO32588.1 - 5.5e-14 52.2 0.0 2.4e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 RhoGAP domain Sel1 PF08238.12 KDO32589.1 - 3.9e-36 122.7 32.8 8.4e-08 32.7 0.1 10.4 10 0 0 10 10 10 8 Sel1 repeat COPIIcoated_ERV PF07970.12 KDO32590.1 - 5.5e-26 91.8 0.2 9.8e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KDO32590.1 - 7.5e-23 80.7 0.1 1.7e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 KDO32590.1 - 3.2e-16 59.2 0.0 7.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO32590.1 - 0.031 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain KNOX2 PF03791.13 KDO32590.1 - 0.15 11.5 0.3 0.4 10.2 0.3 1.7 1 0 0 1 1 1 0 KNOX2 domain Acetyltransf_3 PF13302.7 KDO32591.1 - 1.4e-20 74.4 0.0 1.6e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KDO32591.1 - 0.0073 16.5 0.0 0.028 14.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO32591.1 - 0.0085 16.3 0.0 0.032 14.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PI3_PI4_kinase PF00454.27 KDO32592.1 - 1.6e-33 116.6 0.0 2.1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 KDO32592.1 - 1.4e-07 31.2 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO32592.1 - 0.0042 16.9 0.1 0.0072 16.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like KAR9 PF08580.10 KDO32594.1 - 6.8 5.1 9.7 8.7 4.8 9.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Pkinase PF00069.25 KDO32595.1 - 6.8e-62 209.2 0.0 1.3e-61 208.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO32595.1 - 5.6e-38 128.9 0.0 4.1e-18 65.2 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO32595.1 - 1.5e-28 99.8 0.0 3e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO32595.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO32595.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 KDO32596.1 - 1.7e-28 100.5 1.0 4.1e-28 99.3 0.3 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KDO32596.1 - 7.1e-13 48.8 0.5 6.5e-07 29.7 0.3 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO32596.1 - 2.5e-09 36.3 0.3 3.1e-05 23.5 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KDO32596.1 - 5.5e-09 34.9 0.3 5e-05 22.5 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO32596.1 - 1.6e-07 31.1 0.2 0.002 17.9 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO32596.1 - 1.5e-06 27.4 1.1 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 EF hand PPP5 PF08321.12 KDO32596.1 - 3.3e-06 27.3 0.0 6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KDO32597.1 - 1.7e-28 100.5 0.9 3.1e-28 99.7 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 KDO32597.1 - 2.2e-11 42.4 3.9 8.4e-07 28.1 0.3 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KDO32597.1 - 6.6e-10 39.3 5.4 5.8e-07 29.9 0.5 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO32597.1 - 5.2e-09 35.3 1.1 1.5e-05 24.5 0.3 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO32597.1 - 5.3e-07 28.9 3.5 4.4e-06 25.9 0.4 3.2 3 0 0 3 3 3 1 EF hand PPP5 PF08321.12 KDO32597.1 - 5.7e-07 29.7 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region EF-hand_8 PF13833.6 KDO32597.1 - 1.1e-06 28.4 4.0 0.00087 19.1 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KDO32597.1 - 0.028 14.8 0.1 0.77 10.1 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain DEC-1_N PF04625.13 KDO32597.1 - 4.7 6.1 8.9 8.1 5.3 8.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region bZIP_2 PF07716.15 KDO32598.1 - 0.00024 21.1 4.5 0.00024 21.1 4.5 2.5 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KDO32598.1 - 0.0096 16.0 2.1 0.0096 16.0 2.1 2.8 3 0 0 3 3 3 1 bZIP transcription factor SusD-like_2 PF12771.7 KDO32598.1 - 0.11 11.4 0.2 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Cnn_1N PF07989.11 KDO32598.1 - 1.8 8.8 5.7 2.4 8.4 0.3 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ParcG PF10274.9 KDO32599.1 - 3.6e-72 242.3 0.0 4.5e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Pkinase PF00069.25 KDO32600.1 - 1.7e-63 214.5 0.0 2e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32600.1 - 2.5e-44 151.5 0.0 3.1e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO32600.1 - 3.5e-05 23.3 0.0 0.0011 18.4 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO32600.1 - 0.00029 19.8 0.0 0.00033 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO32600.1 - 0.0029 16.6 0.1 0.005 15.8 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KDO32600.1 - 0.0086 15.7 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KDO32600.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KDO32600.1 - 0.036 13.7 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DMA PF03474.14 KDO32600.1 - 0.13 11.9 0.2 20 4.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif PIP49_C PF12260.8 KDO32600.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Sulfate_transp PF00916.20 KDO32600.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Sulfate permease family Pro-kuma_activ PF09286.11 KDO32601.1 - 1.5e-20 74.0 0.0 2.6e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KDO32601.1 - 1.7e-06 27.5 1.1 3.3e-06 26.6 1.1 1.5 1 0 0 1 1 1 1 Subtilase family Levi_coat PF01819.17 KDO32601.1 - 0.059 13.4 0.1 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Levivirus coat protein Pkinase PF00069.25 KDO32602.1 - 2.8e-51 174.4 0.0 3.8e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32602.1 - 2.1e-50 171.5 0.0 3.8e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO32602.1 - 4.2e-05 22.5 0.2 4.2e-05 22.5 0.2 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO32602.1 - 0.034 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CCAP PF11105.8 KDO32602.1 - 0.065 13.2 0.2 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a APH PF01636.23 KDO32602.1 - 0.075 12.9 0.2 0.54 10.1 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Podoplanin PF05808.11 KDO32602.1 - 2.3 8.3 4.5 2.9 8.0 0.5 2.2 1 1 1 2 2 2 0 Podoplanin Pkinase_Tyr PF07714.17 KDO32603.1 - 6.1e-52 176.5 0.0 8.3e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO32603.1 - 5.6e-50 170.2 0.0 7.6e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO32603.1 - 0.00038 19.3 0.3 0.00055 18.8 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO32603.1 - 0.0013 17.7 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Hum_adeno_E3A PF05393.11 KDO32603.1 - 0.021 14.8 0.1 0.054 13.5 0.1 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Pkinase PF00069.25 KDO32604.1 - 4.1e-48 164.0 0.0 5.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32604.1 - 8.2e-47 159.7 0.0 1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO32604.1 - 7.5e-05 21.7 0.6 0.00011 21.1 0.6 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO32604.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO32604.1 - 0.035 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1180 PF06679.12 KDO32604.1 - 1.2 9.6 3.7 0.37 11.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HAD_2 PF13419.6 KDO32605.1 - 1.4e-25 90.4 0.0 1.6e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO32605.1 - 2.2e-15 57.5 0.7 2.4e-10 41.0 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO32605.1 - 2.8e-06 27.3 0.1 6.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KDO32605.1 - 0.00029 21.3 0.0 0.00047 20.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pex24p PF06398.11 KDO32606.1 - 1.7e-07 30.6 0.1 2.5e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin YL1 PF05764.13 KDO32608.1 - 0.00082 19.6 3.1 0.0015 18.7 3.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein RCS1 PF07326.11 KDO32608.1 - 0.21 11.5 5.3 0.13 12.2 0.4 2.4 2 1 0 2 2 2 0 Regulator of chromosome segregation 1 TBCC PF07986.12 KDO32609.1 - 1.2e-38 131.5 5.7 1.9e-38 130.8 5.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KDO32609.1 - 0.0087 15.7 2.0 0.014 15.0 2.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Asp PF00026.23 KDO32610.1 - 8.1e-43 147.0 0.0 2.6e-42 145.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO32610.1 - 1.4e-18 67.8 1.5 4.3e-16 59.7 1.5 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KDO32610.1 - 0.015 15.9 0.2 4 8.1 0.2 3.0 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KDO32610.1 - 0.072 12.9 0.0 0.73 9.6 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal MARVEL PF01284.23 KDO32611.1 - 1.9e-05 24.7 9.0 2.7e-05 24.2 9.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain PsbM PF05151.12 KDO32612.1 - 1.1 9.1 12.5 0.93 9.4 0.1 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre M protein (PsbM) EF-hand_7 PF13499.6 KDO32613.1 - 0.015 15.8 0.6 0.041 14.3 0.6 1.8 1 0 0 1 1 1 0 EF-hand domain pair ABC_tran PF00005.27 KDO32614.1 - 3.9e-55 186.1 0.0 8.3e-31 107.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO32614.1 - 4.6e-55 187.2 27.0 1.6e-32 113.2 1.7 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region MMR_HSR1 PF01926.23 KDO32614.1 - 6.6e-08 32.6 1.4 0.0083 16.2 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KDO32614.1 - 8.2e-08 32.0 7.0 0.17 11.3 0.1 4.2 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO32614.1 - 1.9e-06 27.5 0.1 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO32614.1 - 4.2e-05 23.5 0.2 0.13 12.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO32614.1 - 7.4e-05 23.2 0.1 0.33 11.3 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KDO32614.1 - 0.00015 21.9 1.2 0.026 14.6 0.1 2.5 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.13 KDO32614.1 - 0.0011 18.1 0.4 0.77 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.6 KDO32614.1 - 0.0048 17.4 0.0 3.4 8.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO32614.1 - 0.005 16.6 0.0 0.5 10.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KDO32614.1 - 0.0056 16.2 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KDO32614.1 - 0.0088 16.2 0.7 0.11 12.5 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 KDO32614.1 - 0.011 14.7 0.4 4.2 6.3 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KDO32614.1 - 0.023 14.0 0.5 1.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KDO32614.1 - 0.024 14.9 0.5 4.5 7.5 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KDO32614.1 - 0.025 13.8 0.2 0.67 9.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_21 PF13304.6 KDO32614.1 - 0.033 14.0 0.8 1.6 8.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KDO32614.1 - 0.053 13.8 1.1 4.6 7.5 0.1 3.0 4 0 0 4 4 2 0 AAA domain cobW PF02492.19 KDO32614.1 - 0.082 12.5 0.4 5.1 6.6 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KDO32614.1 - 0.13 12.3 0.1 3.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 KDO32614.1 - 0.24 11.0 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KDO32614.1 - 0.33 10.6 3.0 18 5.0 0.0 3.1 4 0 0 4 4 3 0 AAA domain ApbA_C PF08546.11 KDO32614.1 - 0.39 10.9 1.2 12 6.1 0.6 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal ABC2_membrane PF01061.24 KDO32615.1 - 3.2e-35 121.4 24.6 4.3e-35 121.1 24.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO32615.1 - 9.4e-11 42.4 0.0 1.5e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO32615.1 - 1.5e-05 25.0 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Filo_VP35 PF02097.15 KDO32615.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Filoviridae VP35 CHAP PF05257.16 KDO32616.1 - 4.9e-12 46.3 0.0 7.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 CHAP domain Ammonium_transp PF00909.21 KDO32620.1 - 2.6e-32 112.0 28.7 3.5e-32 111.6 28.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Chlor_dismutase PF06778.12 KDO32621.1 - 0.037 13.6 0.6 0.059 12.9 0.6 1.3 1 0 0 1 1 1 0 Chlorite dismutase NIF PF03031.18 KDO32623.1 - 5.5e-43 146.4 0.0 6.6e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Kinesin PF00225.23 KDO32624.1 - 3.5e-99 331.9 0.1 1.1e-98 330.2 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO32624.1 - 3.4e-24 85.5 0.0 8.2e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Ank_2 PF12796.7 KDO32625.1 - 1.9e-22 79.7 7.0 3.4e-06 27.5 0.2 5.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32625.1 - 3.7e-17 62.5 8.8 1.5e-05 25.4 0.1 7.8 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32625.1 - 4.8e-12 45.9 10.9 0.42 11.0 0.0 9.1 3 3 6 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32625.1 - 7.7e-09 35.1 1.1 7.5 7.5 0.0 9.3 9 0 0 9 9 9 1 Ankyrin repeat DUF1843 PF08898.10 KDO32625.1 - 0.0013 19.2 0.9 0.77 10.3 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF1843) Ank PF00023.30 KDO32625.1 - 0.0034 17.8 1.8 79 4.0 0.6 6.1 4 2 0 4 4 4 0 Ankyrin repeat Ribosomal_L28 PF00830.19 KDO32626.1 - 3.7e-18 65.5 0.3 5.6e-18 64.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Enolase_C PF00113.22 KDO32627.1 - 4.1e-147 489.1 0.5 5.1e-147 488.8 0.5 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KDO32627.1 - 6e-54 181.7 0.0 1.1e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KDO32627.1 - 9.1e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KDO32627.1 - 8.5e-06 25.1 0.2 1.6e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Mu-like_Pro PF10123.9 KDO32628.1 - 0.0086 15.7 0.7 0.0086 15.7 0.7 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein ABC_tran_CTD PF16326.5 KDO32628.1 - 2.1 8.7 5.3 0.59 10.4 0.3 2.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain ATP_bind_3 PF01171.20 KDO32629.1 - 1.9e-48 164.7 0.0 2.5e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KDO32629.1 - 1.9e-07 31.1 0.3 7.6e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 KDO32629.1 - 0.0042 16.6 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Kinesin PF00225.23 KDO32630.1 - 2.6e-29 102.2 0.0 3.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SPT6_acidic PF14632.6 KDO32630.1 - 0.0088 16.6 0.5 0.19 12.3 0.1 2.6 3 0 0 3 3 3 1 Acidic N-terminal SPT6 DUF1192 PF06698.11 KDO32630.1 - 0.02 14.9 7.0 0.12 12.5 5.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PEP-utilisers_N PF05524.13 KDO32630.1 - 0.049 13.8 1.4 0.15 12.2 1.4 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 KDO32630.1 - 0.071 13.8 0.8 0.19 12.4 0.8 1.6 1 0 0 1 1 1 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KDO32630.1 - 0.13 12.3 1.6 0.24 11.4 1.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KDO32630.1 - 0.47 10.6 0.1 0.47 10.6 0.1 3.7 2 1 1 3 3 3 0 bZIP transcription factor NIF PF03031.18 KDO32632.1 - 2.4e-24 85.9 0.4 4.6e-24 85.0 0.4 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RTT107_BRCT_5 PF16770.5 KDO32632.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KDO32632.1 - 0.014 15.7 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KDO32632.1 - 0.097 13.1 0.0 0.76 10.2 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain NPR2 PF06218.11 KDO32633.1 - 6.5e-92 308.6 8.8 3.4e-86 289.7 8.8 3.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NinF PF05810.12 KDO32633.1 - 0.13 12.1 1.7 0.89 9.5 0.1 2.7 2 0 0 2 2 2 0 NinF protein Tub PF01167.18 KDO32634.1 - 1.4e-89 300.0 0.0 2e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 KDO32634.1 - 0.00064 19.4 0.0 0.0061 16.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) tRNA_SAD PF07973.14 KDO32635.1 - 2.2e-06 27.6 0.3 4.5e-06 26.6 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KDO32635.1 - 1e-05 24.3 0.0 1.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KDO32635.1 - 0.018 15.4 1.8 0.037 14.5 1.8 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3703 PF12487.8 KDO32635.1 - 0.076 12.9 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) SBP_bac_3 PF00497.20 KDO32635.1 - 0.12 11.7 0.5 13 5.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 FAT PF02259.23 KDO32636.1 - 3.1e-39 135.2 6.4 3.1e-39 135.2 6.4 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KDO32636.1 - 2.1e-09 37.6 0.2 8.8e-09 35.5 0.2 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KDO32636.1 - 4.8e-06 26.3 0.3 1.4e-05 24.8 0.3 1.9 1 0 0 1 1 1 1 FATC domain Malate_synthase PF01274.22 KDO32637.1 - 1.4e-200 667.1 0.0 1.6e-200 666.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Myb_DNA-binding PF00249.31 KDO32638.1 - 5.9e-09 36.0 0.2 1.1e-08 35.2 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO32638.1 - 3.1e-08 33.7 0.0 6.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ank_2 PF12796.7 KDO32639.1 - 7.1e-29 100.2 9.4 9.9e-07 29.3 0.1 5.3 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32639.1 - 4.8e-26 90.8 4.7 6.2e-06 26.7 0.0 8.2 4 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32639.1 - 2.1e-17 63.0 5.5 0.2 12.0 0.0 9.7 3 3 7 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32639.1 - 2.8e-11 42.6 0.4 4.4 8.2 0.0 9.8 11 0 0 11 11 11 1 Ankyrin repeat Ank PF00023.30 KDO32639.1 - 0.00053 20.3 3.8 66 4.2 0.0 7.2 3 2 3 6 6 6 0 Ankyrin repeat DUF1843 PF08898.10 KDO32639.1 - 0.0029 18.1 3.9 1.7 9.2 0.0 5.6 7 0 0 7 7 7 1 Domain of unknown function (DUF1843) FaeA PF04703.12 KDO32639.1 - 0.056 13.8 0.0 0.8 10.1 0.0 2.6 2 0 0 2 2 2 0 FaeA-like protein DUF3447 PF11929.8 KDO32639.1 - 0.098 12.6 0.0 9.5 6.3 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) DUF411 PF04214.13 KDO32639.1 - 0.13 12.2 1.7 23 5.0 0.1 4.2 2 1 2 4 4 4 0 Protein of unknown function, DUF Vasohibin PF14822.6 KDO32640.1 - 2e-58 197.5 0.0 3.2e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Vasohibin TTL PF03133.15 KDO32641.1 - 7.1e-31 107.4 0.0 8.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO32641.1 - 0.00056 19.2 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO32641.1 - 0.00099 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KDO32641.1 - 0.04 14.0 0.0 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_M50B PF13398.6 KDO32642.1 - 7.5e-54 182.4 16.4 7.5e-54 182.4 16.4 1.7 1 1 1 2 2 2 1 Peptidase M50B-like Kinesin PF00225.23 KDO32644.1 - 2.5e-24 85.8 0.0 8.5e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain DUF4472 PF14739.6 KDO32644.1 - 3.2e-23 82.5 10.7 3.2e-23 82.5 10.7 6.8 4 2 2 6 6 6 1 Domain of unknown function (DUF4472) Microtub_bd PF16796.5 KDO32644.1 - 8.1e-08 32.3 0.0 3.9e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Exo_endo_phos_2 PF14529.6 KDO32644.1 - 0.014 15.2 0.1 0.13 12.1 0.1 2.6 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase SlyX PF04102.12 KDO32644.1 - 0.026 15.1 2.6 0.026 15.1 2.6 7.7 7 1 2 9 9 9 0 SlyX bZIP_1 PF00170.21 KDO32644.1 - 0.09 12.9 0.2 0.09 12.9 0.2 6.5 6 1 1 7 7 7 0 bZIP transcription factor TPR_22 PF18833.1 KDO32644.1 - 0.39 10.9 2.6 5.5 7.2 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Dam1 PF08653.10 KDO32644.1 - 2 8.3 7.2 5.3 6.9 0.1 4.4 5 0 0 5 5 5 0 DASH complex subunit Dam1 NAD_binding_1 PF00175.21 KDO32645.1 - 2.8e-31 108.4 0.0 4.9e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KDO32645.1 - 2.8e-25 88.5 0.0 5.3e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KDO32645.1 - 1.5e-07 31.7 0.0 2.5e-05 24.4 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Kinesin PF00225.23 KDO32646.1 - 2.2e-88 296.4 0.2 2.2e-88 296.4 0.2 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO32646.1 - 2e-15 57.0 0.2 4e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 KDO32646.1 - 0.0018 18.5 0.6 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain ISET-FN3_linker PF16625.5 KDO32646.1 - 0.039 14.5 0.4 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO AAA_16 PF13191.6 KDO32646.1 - 0.052 13.9 1.3 0.14 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ApeA_NTD1 PF18862.1 KDO32646.1 - 0.099 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 ApeA N-terminal domain 1 UPF0242 PF06785.11 KDO32646.1 - 3.2 7.8 14.2 0.6 10.2 7.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KDO32646.1 - 3.7 8.2 6.7 1.6 9.4 1.3 3.0 2 0 0 2 2 2 0 SlyX TB2_DP1_HVA22 PF03134.19 KDO32647.1 - 3.6e-31 106.9 7.5 5.7e-31 106.3 7.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Baculo_PEP_N PF04512.12 KDO32647.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus TB2_DP1_HVA22 PF03134.19 KDO32648.1 - 2.3e-15 56.3 0.8 3.5e-15 55.7 0.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Nramp PF01566.18 KDO32648.1 - 0.04 12.9 0.1 0.048 12.6 0.1 1.1 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein FragX_IP PF05994.11 KDO32649.1 - 2.1e-123 413.2 0.0 2.4e-78 264.1 0.0 4.1 2 1 2 4 4 4 4 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KDO32649.1 - 8e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.6 KDO32649.1 - 0.00093 17.8 0.3 0.002 16.7 0.3 1.5 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal UQ_con PF00179.26 KDO32650.1 - 4.2e-16 58.9 0.0 5.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KDO32650.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Glucan_synthase PF02364.15 KDO32651.1 - 4.1e-175 584.3 12.0 9.6e-152 507.0 5.8 3.0 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO32651.1 - 2.5e-20 73.1 4.2 1e-19 71.1 1.3 3.0 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_10 PF13374.6 KDO32651.1 - 0.00016 21.4 0.6 0.0018 18.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO32651.1 - 0.012 15.9 2.7 0.31 11.3 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_5 PF13202.6 KDO32651.1 - 0.051 13.1 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 0 EF hand TPR_2 PF07719.17 KDO32651.1 - 0.073 13.2 0.2 0.35 11.1 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Glucan_synthase PF02364.15 KDO32652.1 - 2.6e-184 614.7 13.6 3.8e-163 544.7 8.1 2.8 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KDO32652.1 - 8.8e-23 81.1 4.2 4.2e-21 75.6 2.0 3.2 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_12 PF13424.6 KDO32652.1 - 0.0007 19.8 1.3 0.055 13.8 0.2 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Shisa PF13908.6 KDO32652.1 - 0.0087 16.3 0.6 0.02 15.2 0.6 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TROVE PF05731.11 KDO32652.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 TROVE domain MIT PF04212.18 KDO32652.1 - 0.021 14.9 0.4 0.051 13.6 0.4 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF2512 PF10710.9 KDO32652.1 - 0.033 13.9 5.3 0.11 12.1 5.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) EF-hand_5 PF13202.6 KDO32652.1 - 0.063 12.8 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 EF hand Orthoreo_P10 PF07204.11 KDO32652.1 - 0.075 13.0 0.1 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TPR_10 PF13374.6 KDO32652.1 - 0.12 12.3 0.7 5.5 7.0 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2116 PF09889.9 KDO32652.1 - 0.33 11.0 2.1 2.1 8.4 2.1 2.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CENP-C_C PF11699.8 KDO32654.1 - 1.9e-06 28.0 0.0 0.0015 18.7 0.0 2.6 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_2 PF07883.11 KDO32654.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 Cupin domain ABC_tran PF00005.27 KDO32655.1 - 1.6e-35 122.6 0.0 6.2e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KDO32655.1 - 5.9e-14 51.6 6.7 1.6e-13 50.2 6.7 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KDO32655.1 - 3.1e-09 37.1 5.7 0.44 10.3 1.6 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO32655.1 - 2e-08 33.9 3.5 0.0018 17.8 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 KDO32655.1 - 2.8e-08 33.2 3.3 2.8e-08 33.2 3.3 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 KDO32655.1 - 5.7e-06 26.8 0.0 0.041 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KDO32655.1 - 9.8e-06 25.5 0.0 0.27 10.9 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KDO32655.1 - 1.2e-05 25.8 0.0 0.094 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 KDO32655.1 - 1.5e-05 24.8 2.4 1.5e-05 24.8 2.4 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 KDO32655.1 - 0.00016 21.6 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KDO32655.1 - 0.00018 21.2 0.2 0.33 10.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KDO32655.1 - 0.0002 21.7 0.0 0.33 11.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 KDO32655.1 - 0.00021 21.2 0.1 0.58 10.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KDO32655.1 - 0.00036 20.8 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KDO32655.1 - 0.00052 19.6 0.3 0.17 11.4 0.2 3.3 2 1 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KDO32655.1 - 0.00052 20.0 2.1 0.068 13.1 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KDO32655.1 - 0.00082 19.1 0.4 0.15 11.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO32655.1 - 0.001 19.6 0.0 2.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KDO32655.1 - 0.001 19.2 0.0 0.77 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 KDO32655.1 - 0.0013 18.7 0.8 0.0013 18.7 0.8 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KDO32655.1 - 0.0014 18.7 1.3 0.0014 18.7 1.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.22 KDO32655.1 - 0.0016 18.1 2.2 0.23 11.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 KDO32655.1 - 0.0018 18.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KDO32655.1 - 0.002 18.4 0.0 0.54 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KDO32655.1 - 0.0021 18.6 1.2 0.0021 18.6 1.2 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KDO32655.1 - 0.0027 17.8 12.7 0.0072 16.4 12.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_23 PF13476.6 KDO32655.1 - 0.0039 17.7 3.4 0.088 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 KDO32655.1 - 0.0041 17.3 13.0 0.011 15.9 13.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_30 PF13604.6 KDO32655.1 - 0.0044 16.8 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 KDO32655.1 - 0.0086 17.0 0.2 0.0086 17.0 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain VirE PF05272.11 KDO32655.1 - 0.011 15.4 0.0 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 KDO32655.1 - 0.015 15.3 0.1 2 8.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 KDO32655.1 - 0.039 13.6 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 KDO32655.1 - 0.047 12.9 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 KDO32655.1 - 0.053 13.6 0.1 19 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KDO32655.1 - 0.075 12.9 1.4 3.3 7.6 0.1 2.7 2 0 0 2 2 2 0 NTPase Septin PF00735.18 KDO32655.1 - 0.15 11.3 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Septin MeaB PF03308.16 KDO32655.1 - 0.18 10.8 0.5 1.6 7.6 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KDO32655.1 - 0.19 11.8 1.4 13 5.9 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.14 KDO32655.1 - 0.35 10.8 2.3 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_17 PF13534.6 KDO32655.1 - 4.5 7.9 12.3 0.072 13.6 1.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KDO32655.1 - 5.7 7.5 11.8 0.4 11.2 1.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF4457 PF14652.6 KDO32656.1 - 1.8e-184 612.4 0.0 1.9e-94 316.6 0.0 3.6 2 1 2 4 4 4 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 KDO32656.1 - 0.11 12.5 0.0 1.5e+02 2.4 0.0 4.3 4 0 0 4 4 4 0 Sad1 / UNC-like C-terminal MCD_N PF17408.2 KDO32656.1 - 0.61 10.2 3.2 2.4 8.4 3.2 2.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Flagellar_rod PF05149.12 KDO32656.1 - 1.6 8.1 12.4 3.2 7.2 12.4 1.4 1 0 0 1 1 1 0 Paraflagellar rod protein Pkinase PF00069.25 KDO32658.1 - 3.6e-30 105.2 0.0 5.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32658.1 - 9.5e-15 54.6 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 KDO32659.1 - 5.6e-08 32.2 11.0 6.5 7.1 0.0 9.0 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 KDO32659.1 - 4.2e-05 23.5 10.9 2.3 9.1 0.1 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 KDO32659.1 - 8e-05 22.9 14.4 0.49 10.9 0.3 6.7 5 2 3 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO32659.1 - 7.9 6.3 17.6 51 3.7 0.0 6.9 6 1 0 6 6 6 0 Leucine rich repeat JAB PF01398.21 KDO32660.1 - 1.6e-12 47.5 0.8 1.6e-11 44.2 0.8 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Streptin-Immun PF11083.8 KDO32660.1 - 0.44 11.0 2.6 1.3 9.4 0.1 2.7 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein RL10P_insert PF17777.1 KDO32661.1 - 2.4e-22 78.7 0.0 3.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KDO32661.1 - 4.9e-16 58.7 0.0 7.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 UPF0086 PF01868.16 KDO32662.1 - 6.9e-20 70.8 0.0 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 TFIIF_alpha PF05793.12 KDO32662.1 - 0.014 14.0 9.6 0.019 13.6 9.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BOP1NT PF08145.12 KDO32663.1 - 7.6e-106 353.8 4.8 7.6e-106 353.8 4.8 2.1 3 0 0 3 3 3 1 BOP1NT (NUC169) domain WD40 PF00400.32 KDO32663.1 - 4.7e-26 90.5 7.9 1.9e-06 28.5 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO32663.1 - 1.4e-10 41.3 0.1 9.2e-05 22.7 0.0 5.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 KDO32663.1 - 0.0036 16.8 22.0 0.0063 16.0 22.0 1.4 1 0 0 1 1 1 1 SDA1 Nup160 PF11715.8 KDO32663.1 - 0.039 12.6 0.0 0.073 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Frtz PF11768.8 KDO32663.1 - 0.044 12.1 0.1 2.2 6.5 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nop14 PF04147.12 KDO32663.1 - 1.7 6.7 31.2 2.6 6.1 31.2 1.2 1 0 0 1 1 1 0 Nop14-like family RSN1_7TM PF02714.15 KDO32665.1 - 8.9e-08 31.8 13.4 8.9e-08 31.8 13.4 3.4 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 KDO32665.1 - 1.4e-06 27.4 10.7 9.6e-06 24.7 4.9 2.5 2 0 0 2 2 2 2 Calcium-activated chloride channel PHM7_cyt PF14703.6 KDO32665.1 - 1.5e-06 28.6 0.2 2.6e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMC PF07810.13 KDO32665.1 - 0.086 13.4 3.2 0.11 13.1 0.2 2.8 2 0 0 2 2 2 0 TMC domain Oxidored_q2 PF00420.24 KDO32665.1 - 0.17 11.6 0.0 0.17 11.6 0.0 3.5 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RSN1_TM PF13967.6 KDO32665.1 - 0.32 10.8 8.7 0.34 10.7 0.2 3.4 4 0 0 4 4 4 0 Late exocytosis, associated with Golgi transport PRIMA1 PF16101.5 KDO32665.1 - 0.4 10.7 2.7 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 PhoLip_ATPase_C PF16212.5 KDO32666.1 - 1.4e-64 218.3 18.3 1.4e-64 218.3 18.3 3.0 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KDO32666.1 - 1.2e-16 60.5 0.0 9.6e-16 57.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO32666.1 - 1.6e-12 48.2 1.8 1e-06 29.2 1.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KDO32666.1 - 1.6e-11 43.7 2.8 1.7e-11 43.6 0.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KDO32666.1 - 1.4e-07 31.2 0.4 6.4e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 KDO32666.1 - 3.1e-05 24.5 0.0 0.079 13.3 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KDO32666.1 - 0.0028 17.4 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NKAIN PF05640.14 KDO32666.1 - 0.14 11.4 9.1 0.32 10.2 9.1 1.6 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein Spc7 PF08317.11 KDO32667.1 - 1.8e-05 23.8 11.6 1.8e-05 23.8 11.6 15.9 1 1 13 15 15 15 9 Spc7 kinetochore protein GAS PF13851.6 KDO32667.1 - 0.001 18.5 7.7 0.001 18.5 7.7 16.1 2 2 14 16 16 16 5 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KDO32667.1 - 0.0057 16.7 2.1 0.0057 16.7 2.1 21.6 3 2 17 22 22 22 7 TPR/MLP1/MLP2-like protein Ank_2 PF12796.7 KDO32668.1 - 6.2e-29 100.4 1.9 1.4e-15 57.6 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO32668.1 - 2.7e-21 75.3 6.1 1.9e-05 24.9 0.1 5.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO32668.1 - 9.8e-19 67.5 2.6 1.7e-07 31.7 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO32668.1 - 1.3e-18 66.5 7.3 7.5e-05 23.0 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KDO32668.1 - 2.7e-17 61.1 7.7 0.0019 18.5 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat SAPS PF04499.15 KDO32668.1 - 0.00025 20.0 0.0 0.00054 18.9 0.0 1.5 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein p450 PF00067.22 KDO32669.1 - 1.6e-72 244.8 0.0 1.4e-71 241.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KDO32670.1 - 1.2e-45 156.2 0.0 1.2e-42 146.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 MULE PF10551.9 KDO32671.1 - 2.8e-07 30.9 0.2 1.2e-06 28.9 0.1 2.1 2 0 0 2 2 2 1 MULE transposase domain zf-CCHC_2 PF13696.6 KDO32671.1 - 3.1e-05 23.7 2.3 7.2e-05 22.5 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle SWIM PF04434.17 KDO32671.1 - 0.015 14.9 4.6 0.034 13.8 0.2 2.6 2 0 0 2 2 2 0 SWIM zinc finger DBD_Tnp_Mut PF03108.15 KDO32671.1 - 0.078 13.0 1.3 0.17 11.9 0.3 2.1 2 0 0 2 2 2 0 MuDR family transposase DnaJ_CXXCXGXG PF00684.19 KDO32671.1 - 1.9 8.9 6.5 1.5 9.3 0.2 3.1 3 0 0 3 3 3 0 DnaJ central domain NPC1_N PF16414.5 KDO32672.1 - 1.2e-12 47.9 19.7 2.3e-12 47.0 19.7 1.4 1 1 0 1 1 1 1 Niemann-Pick C1 N terminus Folate_rec PF03024.14 KDO32672.1 - 0.0019 18.1 6.6 0.0019 18.1 6.6 1.9 2 1 0 2 2 2 1 Folate receptor family 2-Hacid_dh_C PF02826.19 KDO32673.1 - 2.8e-33 114.8 0.0 4.4e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO32673.1 - 2.6e-09 36.8 0.0 1.8e-08 34.2 0.0 2.5 3 1 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KDO32673.1 - 6.6e-05 23.1 0.1 0.00014 22.1 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 KDO32673.1 - 0.00029 20.5 0.0 0.00078 19.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain CheC PF04509.12 KDO32673.1 - 0.079 12.9 0.1 3 7.8 0.0 2.6 2 0 0 2 2 2 0 CheC-like family Peptidase_S10 PF00450.22 KDO32674.1 - 4.2e-118 395.4 0.0 5.3e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KDO32675.1 - 7.1e-113 378.2 0.0 8.8e-113 377.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CwfJ_C_1 PF04677.15 KDO32676.1 - 1.2e-30 105.9 0.0 2.2e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KDO32676.1 - 3.5e-26 92.0 0.1 3.5e-26 92.0 0.1 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 ABC_membrane PF00664.23 KDO32678.1 - 2e-103 345.8 28.5 1.6e-56 192.0 5.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO32678.1 - 8.3e-60 201.3 0.0 4.3e-31 108.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KDO32678.1 - 5.9e-08 32.3 0.5 0.0038 16.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KDO32678.1 - 1.1e-06 28.3 6.4 0.16 11.4 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KDO32678.1 - 5.7e-06 26.8 2.3 0.018 15.5 0.0 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO32678.1 - 2.4e-05 24.6 0.8 0.17 12.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KDO32678.1 - 2.7e-05 23.5 0.0 0.038 13.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 KDO32678.1 - 9.5e-05 22.8 4.4 0.032 14.6 0.2 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KDO32678.1 - 0.00014 21.5 3.5 0.87 9.1 0.0 4.1 5 0 0 5 5 5 2 AAA domain AAA_21 PF13304.6 KDO32678.1 - 0.00029 20.8 0.0 2.5 7.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KDO32678.1 - 0.00051 19.8 2.1 0.62 9.7 0.5 3.3 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KDO32678.1 - 0.00067 19.6 0.1 1.4 8.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KDO32678.1 - 0.0014 18.8 0.1 2 8.5 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_7 PF12775.7 KDO32678.1 - 0.0025 17.4 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 KDO32678.1 - 0.0026 17.0 0.0 0.99 8.5 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 KDO32678.1 - 0.0029 17.6 2.1 0.83 9.6 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO32678.1 - 0.0035 17.5 0.7 2.2 8.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KDO32678.1 - 0.0035 17.9 0.3 1.8 9.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KDO32678.1 - 0.0049 16.6 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain NTPase_1 PF03266.15 KDO32678.1 - 0.0054 16.7 0.1 4.4 7.2 0.0 3.4 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.6 KDO32678.1 - 0.0098 15.6 0.2 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KDO32678.1 - 0.013 15.4 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_ATPase PF09818.9 KDO32678.1 - 0.018 13.9 0.5 0.22 10.3 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 KDO32678.1 - 0.035 14.4 0.2 13 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KDO32678.1 - 0.04 14.0 0.1 11 6.1 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KDO32678.1 - 0.051 12.9 0.0 6.4 6.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KDO32678.1 - 0.064 13.0 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KDO32678.1 - 0.07 13.6 0.7 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KDO32678.1 - 0.12 12.8 1.0 28 5.1 0.0 3.9 4 0 0 4 4 3 0 AAA domain SbcCD_C PF13558.6 KDO32678.1 - 0.16 12.2 4.3 13 6.1 0.3 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KDO32678.1 - 0.18 11.6 0.8 89 2.8 0.0 4.1 4 1 1 5 5 5 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 KDO32678.1 - 0.2 11.4 1.1 6.9 6.4 0.0 3.1 4 0 0 4 4 3 0 IstB-like ATP binding protein NACHT PF05729.12 KDO32678.1 - 0.46 10.4 3.4 39 4.1 0.0 3.7 4 0 0 4 4 3 0 NACHT domain Methyltransf_31 PF13847.6 KDO32679.1 - 2.2e-15 56.8 0.0 2.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO32679.1 - 2.5e-14 53.2 0.0 3.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KDO32679.1 - 5e-12 46.4 0.1 1.1e-11 45.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KDO32679.1 - 1.5e-09 38.3 0.1 5.1e-09 36.6 0.1 2.0 2 0 0 2 2 1 1 PrmC N-terminal domain PrmA PF06325.13 KDO32679.1 - 4.9e-09 36.0 0.0 6.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KDO32679.1 - 3e-07 30.3 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KDO32679.1 - 3.5e-07 30.8 0.1 6.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO32679.1 - 5.5e-07 29.6 0.0 3.8e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 KDO32679.1 - 3e-06 26.8 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Cons_hypoth95 PF03602.15 KDO32679.1 - 7.3e-06 25.7 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 KDO32679.1 - 9.3e-06 26.3 0.0 2.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KDO32679.1 - 0.003 17.6 0.0 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KDO32679.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KDO32679.1 - 0.019 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KDO32679.1 - 0.021 14.1 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6_Mtase PF02384.16 KDO32679.1 - 0.024 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_20 PF12147.8 KDO32679.1 - 0.067 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.17 KDO32679.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.7 KDO32679.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.31 KDO32680.1 - 2.3e-11 43.7 0.0 3.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Polysacc_deac_2 PF04748.13 KDO32680.1 - 0.075 12.2 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase AMP-binding PF00501.28 KDO32681.1 - 1e-88 297.8 0.0 1.4e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO32681.1 - 7e-05 23.7 0.0 0.00014 22.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GFO_IDH_MocA PF01408.22 KDO32681.1 - 0.01 16.6 0.0 0.023 15.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF5115 PF17142.4 KDO32681.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) Peptidase_M16_M PF16187.5 KDO32682.1 - 1.9e-85 286.5 0.2 3e-85 285.9 0.2 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KDO32682.1 - 1.5e-42 145.1 0.8 5.1e-40 136.9 0.1 3.1 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO32682.1 - 4.5e-31 108.3 0.0 9.7e-20 71.3 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain PIF1 PF05970.14 KDO32683.1 - 9.8e-16 57.9 0.9 1.1e-14 54.4 0.8 2.2 1 1 1 2 2 2 1 PIF1-like helicase DDDD PF10161.9 KDO32683.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Fungal_TACC PF12709.7 KDO32684.1 - 0.11 12.9 0.8 0.29 11.6 0.8 1.6 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Phage_holin_3_5 PF16085.5 KDO32684.1 - 0.18 12.0 6.6 0.8 9.9 6.6 2.1 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III PriC PF07445.12 KDO32685.1 - 0.039 13.9 0.1 0.053 13.5 0.1 1.1 1 0 0 1 1 1 0 Primosomal replication protein priC Dynactin_p22 PF07426.11 KDO32686.1 - 1.7e-10 41.0 1.2 2.1e-10 40.7 1.2 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Syntaxin-6_N PF09177.11 KDO32686.1 - 0.071 13.7 1.2 12 6.5 0.0 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Pex2_Pex12 PF04757.14 KDO32687.1 - 3.9e-34 118.2 0.5 4.8e-34 117.9 0.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KDO32687.1 - 0.023 14.5 2.6 0.044 13.6 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO32687.1 - 0.17 11.8 5.9 0.3 11.0 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO32687.1 - 0.57 10.6 4.7 1.1 9.6 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain Proteasome PF00227.26 KDO32688.1 - 3.9e-43 147.1 0.1 5.7e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit FTHFS PF01268.19 KDO32689.1 - 6.4e-237 787.2 0.1 7.3e-237 787.0 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase KIAA1430 PF13879.6 KDO32690.1 - 7.6e-16 58.7 2.2 1.6e-15 57.7 2.2 1.6 1 0 0 1 1 1 1 KIAA1430 homologue RNA_pol_Rpb5_N PF03871.14 KDO32690.1 - 0.14 12.8 2.0 0.43 11.2 2.0 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Endonuc_Holl PF10107.9 KDO32690.1 - 8.9 6.1 6.5 0.63 9.9 0.9 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF2854 PF11016.8 KDO32691.1 - 0.47 10.3 4.1 0.23 11.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) OmpH PF03938.14 KDO32691.1 - 1.1 9.6 5.7 0.34 11.2 1.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SAM_2 PF07647.17 KDO32692.1 - 7.8e-12 45.1 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO32692.1 - 6.1e-11 42.6 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-FCS PF06467.14 KDO32692.1 - 0.00027 20.8 1.1 0.00054 19.8 1.1 1.5 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif SAM_PNT PF02198.16 KDO32692.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RPAP2_Rtr1 PF04181.13 KDO32692.1 - 0.084 13.2 1.0 0.22 11.9 1.0 1.7 1 0 0 1 1 1 0 Rtr1/RPAP2 family DUF3043 PF11241.8 KDO32692.1 - 0.38 10.8 7.5 0.63 10.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pkinase PF00069.25 KDO32693.1 - 6e-45 153.7 0.0 1.1e-33 116.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32693.1 - 1.6e-28 99.7 0.0 1.7e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KDO32693.1 - 0.00037 19.9 0.0 0.00084 18.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO32693.1 - 0.0018 17.6 0.0 0.0061 15.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO32693.1 - 0.006 16.2 0.1 3.1 7.4 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KDO32693.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Nup214_FG PF18617.1 KDO32693.1 - 0.21 12.1 0.3 0.62 10.6 0.2 1.8 2 0 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Aminotran_1_2 PF00155.21 KDO32695.1 - 2.1e-50 172.0 0.0 2.4e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KDO32695.1 - 2.2e-05 23.2 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KDO32695.1 - 0.00019 20.5 0.0 0.00065 18.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KDO32695.1 - 0.01 14.6 0.0 0.2 10.3 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KDO32695.1 - 0.074 12.3 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 KDO32695.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 KDO32695.1 - 0.12 11.7 0.2 0.74 9.1 0.2 2.1 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family STAS_2 PF13466.6 KDO32695.1 - 0.13 12.6 2.2 0.53 10.7 0.3 2.6 2 0 0 2 2 2 0 STAS domain DUF2808 PF10989.8 KDO32696.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF1077 PF06417.12 KDO32697.1 - 7.4e-39 132.4 1.0 9.5e-39 132.1 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) EF-hand_6 PF13405.6 KDO32698.1 - 1.1e-09 37.4 2.9 0.065 13.2 0.0 7.1 8 0 0 8 8 8 2 EF-hand domain EF-hand_7 PF13499.6 KDO32698.1 - 2.6e-09 37.4 0.1 0.1 13.1 0.0 5.0 4 1 2 6 6 6 4 EF-hand domain pair EF-hand_8 PF13833.6 KDO32698.1 - 4.7e-08 32.8 0.5 0.65 9.9 0.0 5.4 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO32698.1 - 1.5e-06 27.3 0.0 0.044 13.3 0.1 4.3 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 KDO32698.1 - 0.0048 17.2 0.0 4.1 7.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KDO32698.1 - 0.55 9.8 2.6 1.7 8.3 0.1 2.9 3 0 0 3 3 3 0 EF hand IL31 PF15209.6 KDO32699.1 - 0.077 12.8 0.4 0.22 11.3 0.4 1.7 2 0 0 2 2 2 0 Interleukin 31 Spt20 PF12090.8 KDO32699.1 - 0.091 12.4 3.9 0.1 12.2 3.9 1.1 1 0 0 1 1 1 0 Spt20 family COMP PF11598.8 KDO32699.1 - 0.093 13.2 0.3 12 6.5 0.0 2.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FAM76 PF16046.5 KDO32699.1 - 0.15 11.4 2.9 0.19 11.1 2.9 1.3 1 0 0 1 1 1 0 FAM76 protein OmpH PF03938.14 KDO32699.1 - 0.24 11.8 6.4 0.37 11.1 6.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2383 PF09537.10 KDO32701.1 - 0.0021 18.4 1.6 1 9.7 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) NdhO PF11910.8 KDO32701.1 - 0.0066 16.6 0.1 0.058 13.6 0.0 2.2 2 0 0 2 2 2 1 Cyanobacterial and plant NDH-1 subunit O DUF2524 PF10732.9 KDO32701.1 - 0.033 14.5 2.6 0.033 14.5 2.6 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF2524) Baculo_LEF5_C PF11792.8 KDO32701.1 - 0.12 12.0 0.1 0.56 9.9 0.1 2.2 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain KELK PF15796.5 KDO32701.1 - 0.53 10.8 5.9 0.33 11.4 3.0 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cep57_MT_bd PF06657.13 KDO32701.1 - 0.78 10.2 4.9 5.9 7.4 0.4 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CTP_synth_N PF06418.14 KDO32702.1 - 1.5e-125 417.9 0.3 2e-125 417.5 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KDO32702.1 - 3.2e-49 167.3 0.0 5.4e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KDO32702.1 - 0.023 14.4 0.0 0.7 9.6 0.0 2.5 2 0 0 2 2 2 0 Peptidase C26 CbiA PF01656.23 KDO32702.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_25 PF13649.6 KDO32703.1 - 2.4e-05 24.9 0.0 0.0018 18.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO32703.1 - 0.00028 20.8 0.1 0.0027 17.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO32703.1 - 0.00075 20.2 0.0 0.021 15.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO32703.1 - 0.0053 17.4 0.0 0.49 11.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 KDO32703.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF938) Hydrolase_6 PF13344.6 KDO32705.1 - 1.9e-32 111.4 0.0 3.6e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO32705.1 - 1.2e-18 66.9 0.0 3e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KDO32705.1 - 6.6e-13 49.4 0.1 1.3e-11 45.2 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KDO32705.1 - 5.6e-06 26.6 0.0 0.0026 17.9 0.0 2.6 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KDO32705.1 - 0.0053 16.4 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PGM_PMM_I PF02878.16 KDO32705.1 - 0.044 13.5 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ADH_zinc_N PF00107.26 KDO32705.1 - 0.085 12.8 1.1 0.38 10.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SET PF00856.28 KDO32706.1 - 1.8e-17 64.3 0.0 6.4e-17 62.4 0.0 1.9 1 1 0 1 1 1 1 SET domain BUD22 PF09073.10 KDO32706.1 - 0.091 12.1 6.0 0.15 11.3 6.0 1.3 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KDO32707.1 - 0.64 9.7 4.4 0.9 9.2 4.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UPRTase PF14681.6 KDO32711.1 - 2e-66 223.4 0.0 2.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KDO32711.1 - 0.0035 16.9 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Proteasome PF00227.26 KDO32713.1 - 2.2e-62 210.0 0.1 2.9e-62 209.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KDO32713.1 - 2.6e-10 39.8 0.4 5.9e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DHHC PF01529.20 KDO32714.1 - 1.5e-24 86.6 11.4 1.5e-24 86.6 11.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pkr1 PF08636.10 KDO32714.1 - 0.05 13.8 1.3 0.05 13.8 1.3 2.6 2 2 1 3 3 3 0 ER protein Pkr1 Pkinase PF00069.25 KDO32715.1 - 1.3e-80 270.6 0.0 1.6e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32715.1 - 3.9e-37 127.9 0.0 5.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO32715.1 - 0.00083 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO32715.1 - 0.0016 17.8 0.0 0.0059 16.0 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO32715.1 - 0.02 13.7 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO32715.1 - 0.04 13.8 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Torsin PF06309.11 KDO32716.1 - 2.2e-10 40.7 0.0 4.6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 KDO32716.1 - 7.2e-05 23.1 0.5 0.00049 20.4 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KDO32716.1 - 0.00014 21.9 0.2 0.0012 18.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO32716.1 - 0.00016 21.8 0.1 0.0013 18.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KDO32716.1 - 0.0002 21.8 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KDO32716.1 - 0.00025 21.1 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KDO32716.1 - 0.00088 19.3 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KDO32716.1 - 0.0014 19.1 0.2 0.048 14.0 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KDO32716.1 - 0.0022 18.6 0.0 0.006 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 KDO32716.1 - 0.018 15.0 0.3 0.54 10.1 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KDO32716.1 - 0.019 14.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KDO32716.1 - 0.043 14.2 1.5 0.89 9.9 1.5 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO32716.1 - 0.065 13.6 0.0 0.58 10.6 0.0 2.4 1 1 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 KDO32716.1 - 0.084 11.8 0.5 0.18 10.7 0.1 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF87 PF01935.17 KDO32716.1 - 0.085 12.9 0.1 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KDO32716.1 - 0.11 12.2 0.6 0.36 10.5 0.6 1.8 1 1 0 1 1 1 0 AAA domain Hairy_orange PF07527.13 KDO32716.1 - 0.12 12.6 0.1 3.4 7.9 0.0 3.0 3 0 0 3 3 3 0 Hairy Orange PhoH PF02562.16 KDO32716.1 - 0.13 11.7 1.0 2.3 7.6 0.2 2.3 1 1 1 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KDO32716.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KH_8 PF17903.1 KDO32717.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KDO32717.1 - 0.00089 19.0 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 KH domain Pkinase PF00069.25 KDO32718.1 - 1.5e-12 47.4 0.0 3.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain WW PF00397.26 KDO32718.1 - 6.4e-10 38.9 0.1 1.1e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 WW domain Pkinase_Tyr PF07714.17 KDO32718.1 - 3e-08 33.3 0.0 5.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ETC_C1_NDUFA4 PF04800.12 KDO32720.1 - 8.2e-30 102.9 0.2 3.7e-29 100.8 0.4 1.9 2 0 0 2 2 2 1 ETC complex I subunit conserved region Kinesin PF00225.23 KDO32722.1 - 1.9e-103 345.9 3.5 2.6e-103 345.5 3.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO32722.1 - 2.7e-18 66.3 0.2 4.7e-15 55.8 0.1 2.7 2 0 0 2 2 2 2 Microtubule binding SOGA PF11365.8 KDO32722.1 - 0.0053 17.9 5.5 0.043 14.9 3.6 2.8 1 1 1 2 2 2 1 Protein SOGA DUF4600 PF15372.6 KDO32722.1 - 0.01 16.3 4.7 0.031 14.7 4.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) UPF0242 PF06785.11 KDO32722.1 - 0.017 15.2 5.3 0.037 14.1 5.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HEPN PF05168.14 KDO32722.1 - 0.025 14.7 1.7 0.025 14.7 1.7 2.4 2 1 1 3 3 2 0 HEPN domain DUF2312 PF10073.9 KDO32722.1 - 0.059 13.0 10.5 0.45 10.2 0.3 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) ZapB PF06005.12 KDO32722.1 - 0.065 13.7 5.0 1.8 9.0 0.4 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Herpes_UL6 PF01763.16 KDO32722.1 - 0.078 11.5 4.3 0.093 11.2 2.6 1.9 1 1 2 3 3 3 0 Herpesvirus UL6 like Spo7_2_N PF15407.6 KDO32722.1 - 0.086 12.5 0.0 0.32 10.6 0.0 2.0 1 0 0 1 1 1 0 Sporulation protein family 7 DUF4635 PF15466.6 KDO32722.1 - 0.18 11.3 1.3 0.32 10.5 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Cnn_1N PF07989.11 KDO32722.1 - 0.24 11.6 6.1 2.7 8.2 1.4 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 KDO32722.1 - 0.31 11.2 7.6 1.9 8.7 0.4 2.8 2 0 0 2 2 2 0 bZIP transcription factor DivIVA PF05103.13 KDO32722.1 - 0.34 11.0 10.0 21 5.2 9.9 2.6 1 1 0 1 1 1 0 DivIVA protein ABC_tran_CTD PF16326.5 KDO32722.1 - 0.35 11.2 7.3 0.28 11.4 1.0 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Lzipper-MIP1 PF14389.6 KDO32722.1 - 0.47 10.8 7.4 1.2 9.4 7.4 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TMF_TATA_bd PF12325.8 KDO32722.1 - 0.9 9.8 10.9 6.1 7.1 1.9 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Com_YlbF PF06133.11 KDO32722.1 - 1.2 9.8 5.9 2.9 8.6 5.9 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF5320 PF17253.2 KDO32722.1 - 1.6 9.8 4.6 13 7.0 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DivIC PF04977.15 KDO32722.1 - 1.6 8.5 8.9 1.6 8.5 0.8 2.9 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.18 KDO32722.1 - 1.7 8.9 10.7 6.3 7.1 2.3 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 KDO32722.1 - 1.7 8.4 13.0 0.26 11.1 8.6 1.8 2 0 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 KDO32722.1 - 1.8 8.8 12.3 1.4 9.2 0.2 2.8 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 KDO32722.1 - 2.8 8.5 13.5 58 4.2 13.5 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region bZIP_2 PF07716.15 KDO32722.1 - 4.4 7.5 13.4 3.5 7.8 1.3 3.2 3 0 0 3 3 2 0 Basic region leucine zipper Uso1_p115_C PF04871.13 KDO32722.1 - 5.4 7.4 10.1 18 5.7 10.1 1.9 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4337 PF14235.6 KDO32722.1 - 5.5 7.1 7.1 1.6 8.8 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fez1 PF06818.15 KDO32722.1 - 6.5 7.2 11.3 3.4 8.1 7.9 2.0 1 1 1 2 2 2 0 Fez1 TMF_DNA_bd PF12329.8 KDO32722.1 - 8.5 6.5 14.6 1.6 8.8 1.5 4.1 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding CorA PF01544.18 KDO32723.1 - 0.0023 17.3 8.0 0.0063 15.9 8.0 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein BAR PF03114.18 KDO32724.1 - 0.064 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 BAR domain CorA PF01544.18 KDO32724.1 - 0.071 12.4 11.8 0.26 10.6 11.8 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2569 PF10754.9 KDO32724.1 - 0.12 12.8 3.0 0.23 11.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) SUR7 PF06687.12 KDO32724.1 - 0.28 10.8 3.8 0.45 10.1 3.8 1.3 1 0 0 1 1 1 0 SUR7/PalI family CorA PF01544.18 KDO32726.1 - 2.9e-07 30.1 6.8 1.7e-06 27.6 6.8 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NPV_P10 PF05531.12 KDO32726.1 - 0.047 14.2 0.2 3.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3212 PF11486.8 KDO32726.1 - 0.11 12.5 1.3 2.4 8.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3212) HEAT_2 PF13646.6 KDO32727.1 - 0.0052 17.2 3.7 0.0076 16.6 0.3 2.5 2 1 0 2 2 2 1 HEAT repeats Myb_DNA-binding PF00249.31 KDO32728.1 - 4.2e-21 74.9 0.5 5.3e-10 39.3 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO32728.1 - 5.8e-08 32.9 0.1 7.6e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO32728.1 - 0.11 12.4 0.0 5.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Myb DNA-binding like DAZAP2 PF11029.8 KDO32731.1 - 0.036 15.0 0.7 0.036 15.0 0.7 1.9 1 1 1 2 2 2 0 DAZ associated protein 2 (DAZAP2) DUF547 PF04784.14 KDO32733.1 - 1.4e-17 63.9 0.0 4.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 RSN1_7TM PF02714.15 KDO32733.1 - 0.11 11.9 0.2 0.33 10.2 0.2 1.8 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate zf-AN1 PF01428.16 KDO32734.1 - 3.2e-20 72.0 37.4 5.7e-13 48.8 8.4 4.5 4 1 1 5 5 5 2 AN1-like Zinc finger zf-Di19 PF05605.12 KDO32734.1 - 7.2e-06 26.2 1.2 0.0073 16.6 0.1 4.1 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KDO32734.1 - 5.3e-05 23.6 3.9 0.23 12.0 0.3 3.6 3 0 0 3 3 3 2 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 KDO32734.1 - 5.5e-05 22.9 0.5 1.8 8.5 0.0 3.6 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-C2H2 PF00096.26 KDO32734.1 - 0.00012 22.3 1.2 0.0017 18.7 0.3 4.3 5 0 0 5 5 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO32734.1 - 0.00019 22.0 1.5 0.036 14.9 0.3 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 KDO32734.1 - 0.00027 20.8 4.3 0.71 9.9 0.3 3.9 3 0 0 3 3 3 1 Ubiquitin-binding zinc-finger zf-C2H2_9 PF16293.5 KDO32734.1 - 0.00056 19.7 2.3 0.76 9.7 0.0 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 KDO32734.1 - 0.011 16.4 9.2 1.2 9.8 0.1 3.9 4 1 0 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 KDO32734.1 - 0.023 15.1 0.0 0.023 15.1 0.0 4.8 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KDO32734.1 - 0.23 11.5 9.8 1.2 9.2 0.0 4.1 4 0 0 4 4 4 0 BED zinc finger Transp_Tc5_C PF04236.15 KDO32734.1 - 0.44 10.9 26.6 0.13 12.6 4.1 3.6 3 1 1 4 4 4 0 Tc5 transposase C-terminal domain Trm112p PF03966.16 KDO32734.1 - 2.1 9.0 7.6 2.8 8.6 2.0 2.9 2 1 0 2 2 2 0 Trm112p-like protein Prok-RING_4 PF14447.6 KDO32734.1 - 3.5 7.6 23.9 7.6 6.5 0.0 4.9 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 IBR PF01485.21 KDO32734.1 - 4.6 7.6 33.7 3.7 7.8 10.8 4.3 2 2 2 4 4 4 0 IBR domain, a half RING-finger domain SUR7 PF06687.12 KDO32737.1 - 0.00014 21.6 5.8 0.00024 20.8 5.8 1.5 1 1 0 1 1 1 1 SUR7/PalI family CPBP PF02517.16 KDO32737.1 - 0.16 12.3 6.2 1.1 9.6 0.9 3.1 3 0 0 3 3 3 0 CPBP intramembrane metalloprotease PI3_PI4_kinase PF00454.27 KDO32738.1 - 6.9e-32 111.2 1.0 5.8e-24 85.3 0.0 2.9 3 1 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KDO32738.1 - 0.00011 21.7 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KDO32738.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Caps_synth_CapC PF14102.6 KDO32738.1 - 0.91 10.0 7.4 2 8.8 7.4 1.5 1 0 0 1 1 1 0 Capsule biosynthesis CapC RCC1 PF00415.18 KDO32739.1 - 1.2e-49 166.7 19.9 8.2e-14 52.0 0.7 8.0 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat WW PF00397.26 KDO32739.1 - 2.1e-33 114.1 40.5 8.8e-07 28.9 1.2 7.5 7 0 0 7 7 7 7 WW domain RCC1_2 PF13540.6 KDO32739.1 - 2.6e-21 74.9 27.1 1.1e-05 25.1 0.1 6.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 KDO32739.1 - 4.3e-09 35.4 27.1 0.69 9.9 0.0 8.2 7 0 0 7 7 7 5 IQ calmodulin-binding motif Hydrolase_2 PF07486.12 KDO32739.1 - 0.62 10.9 22.9 4.8 8.1 0.3 6.1 4 2 2 6 6 6 0 Cell Wall Hydrolase Sporozoite_P67 PF05642.11 KDO32739.1 - 0.88 7.6 2.1 1.5 6.8 2.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hyd_101C PF17451.2 KDO32739.1 - 3.9 7.8 10.8 0.81 10.0 0.1 4.1 3 1 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Dicty_REP PF05086.12 KDO32739.1 - 9.5 4.0 5.9 15 3.4 5.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Exo_endo_phos PF03372.23 KDO32740.1 - 2.9e-11 43.3 0.1 4.2e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KDO32740.1 - 0.012 15.5 0.0 0.087 12.7 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase CBFD_NFYB_HMF PF00808.23 KDO32741.1 - 4.1e-23 81.4 0.1 7e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO32741.1 - 6.9e-18 65.3 0.6 7.9e-18 65.1 0.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KDO32741.1 - 0.007 16.5 0.4 0.019 15.1 0.1 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.16 KDO32741.1 - 0.095 12.7 0.6 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Dpy-30 PF05186.13 KDO32743.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif TMEM37 PF15108.6 KDO32743.1 - 0.05 13.5 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family NinB PF05772.12 KDO32744.1 - 0.059 13.2 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 NinB protein DUF5134 PF17197.4 KDO32744.1 - 0.091 12.7 0.7 0.11 12.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) AMP-binding PF00501.28 KDO32745.1 - 2e-68 231.0 0.0 3.2e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO32745.1 - 2e-05 25.5 0.0 4.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ASH PF15780.5 KDO32746.1 - 3.8e-07 30.2 0.0 0.0093 16.2 0.0 2.6 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KDO32746.1 - 2.2e-05 24.5 0.1 8.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 KDO32746.1 - 0.0053 17.0 0.0 0.21 11.9 0.0 2.8 2 1 0 2 2 2 1 Transmembrane protein 131-like ATP-synt_DE PF00401.20 KDO32746.1 - 0.023 15.0 0.6 0.023 15.0 0.6 2.7 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain EF-hand_1 PF00036.32 KDO32747.1 - 6.7e-11 40.9 0.0 7.3e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KDO32747.1 - 2.3e-10 39.5 0.2 0.00012 21.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO32747.1 - 2.7e-10 39.3 0.0 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO32747.1 - 1.2e-09 37.9 0.3 1.1e-08 34.8 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KDO32747.1 - 6.1e-09 36.2 0.3 1.3e-08 35.2 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 KDO32747.1 - 0.015 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO32747.1 - 0.032 14.5 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region zf-C3HC4_3 PF13920.6 KDO32748.1 - 0.0015 18.3 15.1 0.0015 18.3 15.1 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 KDO32748.1 - 0.012 16.0 20.9 0.28 11.7 0.1 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Arc_trans_TRASH PF08394.10 KDO32748.1 - 6.7 7.1 9.0 0.46 10.9 2.4 2.5 2 0 0 2 2 2 0 Archaeal TRASH domain ARS2 PF04959.13 KDO32749.1 - 0.00065 20.1 0.6 0.0013 19.1 0.6 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF2752 PF10825.8 KDO32749.1 - 0.023 14.7 0.4 0.078 13.0 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) zf-BED PF02892.15 KDO32749.1 - 0.041 13.9 0.8 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KDO32749.1 - 0.064 13.6 0.4 0.064 13.6 0.4 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_UL33 PF03581.13 KDO32749.1 - 0.11 12.9 0.4 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL33-like protein zf-C2H2_4 PF13894.6 KDO32749.1 - 0.16 12.9 5.4 0.21 12.5 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger A2L_zn_ribbon PF08792.10 KDO32749.1 - 0.29 10.9 1.8 12 5.8 0.3 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-Di19 PF05605.12 KDO32749.1 - 0.35 11.2 8.3 0.29 11.5 2.8 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ephrin_rec_like PF07699.13 KDO32750.1 - 1.5e-08 34.3 63.2 0.00066 19.4 6.9 8.5 6 2 3 9 9 9 5 Putative ephrin-receptor like NCD3G PF07562.14 KDO32750.1 - 0.00017 21.5 37.3 0.03 14.3 7.2 6.5 5 1 1 6 6 6 4 Nine Cysteines Domain of family 3 GPCR SKG6 PF08693.10 KDO32750.1 - 0.47 9.9 4.3 1.1 8.7 4.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AA_kinase PF00696.28 KDO32751.1 - 2.1e-33 115.9 1.1 4e-33 115.0 1.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 KDO32751.1 - 1.9e-32 112.6 0.1 3.4e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT_7 PF13840.6 KDO32751.1 - 4.9e-05 23.0 0.3 0.046 13.5 0.1 3.4 3 0 0 3 3 3 2 ACT domain NAD_binding_3 PF03447.16 KDO32751.1 - 0.00012 22.7 3.3 0.00031 21.4 0.0 3.1 3 1 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain Ctr PF04145.15 KDO32752.1 - 3.4e-14 53.7 14.9 5.9e-12 46.4 14.9 2.3 1 1 0 1 1 1 1 Ctr copper transporter family HMA PF00403.26 KDO32752.1 - 0.00012 22.4 0.1 0.00021 21.7 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain YHS PF04945.13 KDO32752.1 - 0.014 15.4 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 YHS domain Ctr PF04145.15 KDO32753.1 - 2.3e-18 67.2 0.2 5.7e-18 66.0 0.2 1.7 1 0 0 1 1 1 1 Ctr copper transporter family Zn_Tnp_IS1595 PF12760.7 KDO32753.1 - 0.1 12.6 0.6 0.37 10.8 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TTL PF03133.15 KDO32754.1 - 4e-33 114.8 0.0 2.4e-32 112.3 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_2 PF07974.13 KDO32754.1 - 5.3e-05 23.5 11.3 9e-05 22.8 11.3 1.4 1 0 0 1 1 1 1 EGF-like domain ATPgrasp_YheCD PF14398.6 KDO32754.1 - 0.0023 17.2 0.0 0.0063 15.8 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp EGF_Tenascin PF18720.1 KDO32754.1 - 0.022 14.8 8.8 0.022 14.8 8.8 1.8 2 0 0 2 2 2 0 Tenascin EGF domain EB PF01683.18 KDO32754.1 - 0.029 14.6 3.7 0.058 13.7 3.7 1.4 1 0 0 1 1 1 0 EB module I-EGF_1 PF18372.1 KDO32754.1 - 0.052 13.6 4.7 0.099 12.8 4.7 1.4 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 KDO32754.1 - 0.06 13.7 5.8 0.11 12.9 5.8 1.4 1 0 0 1 1 1 0 EGF-like domain Dala_Dala_lig_C PF07478.13 KDO32754.1 - 0.08 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus hEGF PF12661.7 KDO32754.1 - 0.29 11.8 4.7 0.65 10.7 4.7 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF TTL PF03133.15 KDO32755.1 - 2.7e-26 92.4 0.0 4.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family EB PF01683.18 KDO32755.1 - 8.3e-05 22.8 0.9 0.00016 21.9 0.9 1.4 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 KDO32755.1 - 0.00035 20.9 13.0 0.00067 20.0 13.0 1.5 1 0 0 1 1 1 1 EGF-like domain I-EGF_1 PF18372.1 KDO32755.1 - 0.064 13.4 5.0 0.11 12.6 5.0 1.4 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 KDO32755.1 - 0.14 12.8 6.4 0.33 11.7 6.4 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 KDO32755.1 - 2.3 8.4 6.7 4.6 7.4 6.7 1.5 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 KDO32755.1 - 2.3 8.6 8.5 4.5 7.7 8.5 1.5 1 0 0 1 1 1 0 EGF-like domain FGase PF05013.12 KDO32756.1 - 0.031 14.5 0.7 0.037 14.2 0.7 1.1 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase ANAPC4_WD40 PF12894.7 KDO32757.1 - 1.1e-11 44.8 4.7 2e-05 24.8 0.1 6.0 3 2 3 6 6 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KDO32757.1 - 1.3e-06 27.8 4.2 0.002 17.2 0.1 3.5 4 0 0 4 4 4 2 Coatomer WD associated region WD40 PF00400.32 KDO32757.1 - 2e-05 25.2 5.0 0.59 11.1 0.1 5.7 5 1 0 5 5 3 2 WD domain, G-beta repeat eIF2A PF08662.11 KDO32757.1 - 0.00062 19.7 0.6 1.7 8.5 0.2 3.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KDO32757.1 - 0.0029 17.5 0.3 0.61 10.1 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TPR_7 PF13176.6 KDO32757.1 - 0.0066 16.4 3.2 2.1 8.6 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO32757.1 - 0.015 15.5 8.4 10 6.4 0.1 4.3 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 IKI3 PF04762.12 KDO32757.1 - 0.034 12.2 0.0 0.16 9.9 0.1 1.9 2 0 0 2 2 2 0 IKI3 family TPR_2 PF07719.17 KDO32757.1 - 0.037 14.2 23.8 0.11 12.7 0.3 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KDO32757.1 - 0.038 12.9 0.1 1.9 7.3 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GvpO PF05800.11 KDO32757.1 - 0.047 13.7 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO TPR_1 PF00515.28 KDO32757.1 - 0.071 13.0 12.3 0.34 10.8 0.3 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Cript PF10235.9 KDO32757.1 - 0.091 13.3 3.6 0.25 11.9 3.6 1.8 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT TPR_14 PF13428.6 KDO32757.1 - 0.095 13.6 18.0 3.6 8.6 0.2 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO32757.1 - 0.21 11.9 13.4 0.44 10.9 0.1 5.2 5 1 0 6 6 6 0 Tetratricopeptide repeat Clathrin PF00637.20 KDO32757.1 - 0.54 10.1 5.8 6.3 6.7 0.2 4.0 2 1 2 4 4 4 0 Region in Clathrin and VPS TPR_16 PF13432.6 KDO32757.1 - 0.79 10.4 16.0 12 6.6 0.2 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat KTI12 PF08433.10 KDO32758.1 - 1.3e-69 234.7 0.0 1.5e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KDO32758.1 - 1.8e-13 50.9 0.1 5.9e-13 49.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KDO32758.1 - 0.0003 20.6 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein APS_kinase PF01583.20 KDO32758.1 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KDO32758.1 - 0.005 17.4 0.0 0.0094 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO32758.1 - 0.024 14.9 0.0 0.062 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO32758.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KDO32758.1 - 0.025 15.0 0.0 0.35 11.3 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KDO32758.1 - 0.028 13.7 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 KDO32758.1 - 0.032 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KDO32758.1 - 0.046 13.3 0.2 0.19 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KDO32758.1 - 0.057 13.4 0.1 2.2 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO32758.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KDO32758.1 - 0.11 12.3 0.4 34 4.3 0.0 3.1 2 2 2 4 4 4 0 P-loop Nucleotide Kinase3 Frag1 PF10277.9 KDO32759.1 - 0.089 12.3 9.6 0.12 11.8 9.6 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Pkinase PF00069.25 KDO32760.1 - 1.5e-63 214.6 0.0 2.1e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32760.1 - 2.6e-30 105.6 0.0 4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO32760.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO32760.1 - 0.02 14.8 0.1 0.05 13.5 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO32760.1 - 0.033 13.2 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KDO32760.1 - 0.043 13.1 0.6 1.4 8.2 0.4 2.3 2 0 0 2 2 2 0 Kinase-like Exo_endo_phos PF03372.23 KDO32761.1 - 2.9e-13 49.9 0.0 4.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KDO32761.1 - 1e-11 44.7 0.4 3e-11 43.2 0.4 1.9 1 0 0 1 1 1 1 GRF zinc finger DUF3489 PF11994.8 KDO32761.1 - 0.014 15.4 0.1 0.035 14.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Exo_endo_phos_2 PF14529.6 KDO32761.1 - 0.069 13.0 0.0 0.46 10.3 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase EF-hand_1 PF00036.32 KDO32762.1 - 0.00032 20.0 0.1 0.0088 15.5 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO32762.1 - 0.00043 20.0 0.1 0.0072 16.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KDO32762.1 - 0.00043 20.7 0.4 0.079 13.4 0.1 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO32762.1 - 0.01 15.3 0.2 0.058 12.9 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KDO32762.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Dockerin_1 PF00404.18 KDO32762.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain Kinesin PF00225.23 KDO32763.1 - 7.5e-89 297.9 0.0 1.1e-88 297.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO32763.1 - 1.8e-22 79.9 0.0 5.8e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH_12 PF16457.5 KDO32763.1 - 0.0013 19.3 0.0 0.0033 17.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PqqD PF05402.12 KDO32763.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DivIC PF04977.15 KDO32763.1 - 0.19 11.5 5.2 3.4 7.5 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator MatE PF01554.18 KDO32764.1 - 0.0018 17.9 4.0 0.0018 17.9 4.0 3.8 4 0 0 4 4 4 3 MatE bZIP_1 PF00170.21 KDO32766.1 - 0.00049 20.1 16.7 0.017 15.2 4.3 2.8 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 KDO32766.1 - 0.0033 17.5 11.6 0.72 10.0 0.3 3.0 2 1 0 2 2 2 2 Basic region leucine zipper ResIII PF04851.15 KDO32766.1 - 0.096 12.7 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit YABBY PF04690.13 KDO32766.1 - 0.17 12.4 2.6 0.2 12.2 2.0 1.4 1 1 0 1 1 1 0 YABBY protein MatE PF01554.18 KDO32767.1 - 2e-30 105.6 37.7 4.6e-18 65.4 15.1 2.3 2 0 0 2 2 2 2 MatE Tim17 PF02466.19 KDO32768.1 - 2.4e-11 44.0 5.1 3.7e-11 43.4 5.1 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EF-hand_7 PF13499.6 KDO32769.1 - 1.4e-24 86.3 3.8 1.9e-08 34.6 0.6 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO32769.1 - 4.3e-19 66.6 7.2 0.00061 19.2 0.0 5.7 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KDO32769.1 - 1.9e-18 64.7 7.4 0.0014 18.4 0.0 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KDO32769.1 - 7.5e-15 54.5 7.4 6.7e-06 25.9 0.1 5.1 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO32769.1 - 5.8e-11 41.4 3.8 0.59 9.7 0.0 5.3 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 KDO32769.1 - 2.3e-08 34.3 0.2 0.25 11.6 0.0 3.4 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KDO32769.1 - 0.0011 18.9 3.0 2.5 8.1 0.0 4.1 4 0 0 4 4 4 1 Tellurite resistance protein TerB EF-hand_9 PF14658.6 KDO32769.1 - 0.015 15.6 0.1 0.051 13.9 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 KDO32769.1 - 0.029 14.3 2.7 0.12 12.3 0.1 2.9 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KDO32769.1 - 0.07 13.0 1.1 67 3.4 0.0 3.8 3 1 1 4 4 4 0 Caleosin related protein TFIIA PF03153.13 KDO32770.1 - 0.00042 20.4 24.1 0.00067 19.8 24.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KDO32770.1 - 3 7.4 21.0 8.1 6.0 21.0 1.8 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 KDO32771.1 - 4e-69 232.9 0.0 5.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32771.1 - 3.6e-34 118.2 0.0 4.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KDO32771.1 - 2e-11 42.6 0.6 4.7e-06 25.8 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO32771.1 - 1.6e-09 38.1 0.1 0.0026 18.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO32771.1 - 3.2e-09 36.5 0.1 4e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.6 KDO32771.1 - 2.1e-08 33.9 0.0 1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.6 KDO32771.1 - 2.5e-08 33.2 0.4 0.39 10.8 0.0 3.8 3 1 0 3 3 3 3 EF-hand domain Kdo PF06293.14 KDO32771.1 - 7e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.6 KDO32771.1 - 0.0046 16.4 0.1 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KDO32771.1 - 0.051 13.5 0.4 2.9 7.9 0.1 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand YrbL-PhoP_reg PF10707.9 KDO32771.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3597 PF12200.8 KDO32772.1 - 0.73 10.4 5.1 0.41 11.2 3.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) DUF4717 PF15838.5 KDO32772.1 - 1.5 8.9 8.1 0.078 13.0 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) Guanylate_cyc PF00211.20 KDO32773.1 - 3.3e-19 69.2 0.2 2.2e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KDO32773.1 - 2.1e-09 38.0 0.6 0.0014 19.1 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KDO32773.1 - 0.00053 20.3 0.2 0.84 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RXT2_N PF08595.11 KDO32773.1 - 0.024 14.7 1.8 0.051 13.6 1.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RsgA_GTPase PF03193.16 KDO32773.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Cnd2 PF05786.14 KDO32773.1 - 0.048 12.3 0.7 0.069 11.8 0.7 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 AAA_33 PF13671.6 KDO32773.1 - 0.072 13.2 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DNA_pol_phi PF04931.13 KDO32773.1 - 1.8 6.5 10.8 2.7 6.0 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 KDO32773.1 - 2.8 8.2 7.0 6.2 7.1 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KDO32773.1 - 5.4 6.2 17.7 3.8 6.8 15.7 1.6 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 KDO32773.1 - 6.2 7.3 19.3 20 5.7 19.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KDO32773.1 - 7.1 5.7 18.0 13 4.8 18.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MatE PF01554.18 KDO32774.1 - 1.3e-32 112.7 35.4 1.1e-19 70.7 14.0 2.3 2 0 0 2 2 2 2 MatE MatE PF01554.18 KDO32775.1 - 9.7e-21 74.1 32.0 3.5e-14 52.8 9.8 2.4 2 0 0 2 2 2 2 MatE CS PF04969.16 KDO32776.1 - 4e-07 30.9 0.3 4e-07 30.9 0.3 1.4 2 0 0 2 2 2 1 CS domain DUF4843 PF16132.5 KDO32776.1 - 0.0078 15.8 0.8 0.01 15.4 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4843) FERM_f0 PF16511.5 KDO32776.1 - 0.052 13.8 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM PIH1_CS PF18201.1 KDO32776.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain PPTA PF01239.22 KDO32778.1 - 3.4e-28 96.5 9.5 1e-07 31.4 0.7 5.1 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Iso_dh PF00180.20 KDO32779.1 - 2.7e-120 401.7 0.0 3.1e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.26 KDO32781.1 - 1.4e-16 59.9 27.5 0.0014 18.9 2.7 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KDO32781.1 - 5.1e-12 45.7 27.9 1.5e-05 25.2 2.3 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO32781.1 - 1.4e-07 31.7 34.6 0.065 14.1 1.9 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KDO32781.1 - 0.00067 19.4 21.2 0.017 14.9 0.2 5.0 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 KDO32781.1 - 0.0027 18.0 10.5 0.56 10.7 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KDO32781.1 - 0.0045 17.6 14.2 9.4 6.9 0.1 5.0 2 1 3 5 5 5 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KDO32781.1 - 0.013 15.8 9.8 3.2 8.1 1.0 3.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 KDO32781.1 - 0.075 13.7 14.4 0.083 13.6 2.9 2.7 3 0 0 3 3 3 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 KDO32781.1 - 0.11 12.8 14.1 0.54 10.6 0.2 5.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KDO32781.1 - 0.55 10.4 9.3 19 5.3 0.1 3.8 1 1 3 4 4 4 0 Aberrant zinc-finger CCAP PF11105.8 KDO32781.1 - 2 8.3 3.8 1.2 9.1 0.3 2.0 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a WW PF00397.26 KDO32782.1 - 5.9e-18 64.7 21.9 2.8e-08 33.7 1.7 3.4 3 0 0 3 3 3 3 WW domain U-box PF04564.15 KDO32782.1 - 1.9e-06 28.0 0.1 3.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KDO32782.1 - 0.0047 16.7 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Glyco_hyd_101C PF17451.2 KDO32782.1 - 0.53 10.6 3.0 31 4.9 0.2 3.1 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain TB2_DP1_HVA22 PF03134.19 KDO32784.1 - 4.8e-11 42.4 8.1 4.8e-11 42.4 8.1 4.6 3 1 1 4 4 4 2 TB2/DP1, HVA22 family TetR_C_6 PF13977.6 KDO32784.1 - 0.51 10.6 7.0 1.4 9.2 1.4 3.2 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal adh_short PF00106.25 KDO32785.1 - 7.8e-34 116.8 1.5 6.7e-32 110.5 1.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO32785.1 - 3.2e-20 72.7 1.7 6.3e-18 65.2 1.6 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO32785.1 - 4.9e-08 33.1 0.9 8.4e-08 32.3 0.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO32785.1 - 0.00053 19.5 0.2 0.0011 18.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Capsid_NCLDV PF04451.12 KDO32785.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Ank_2 PF12796.7 KDO32786.1 - 5.2e-20 71.8 6.5 7.8e-06 26.4 0.1 5.8 4 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32786.1 - 8.4e-16 58.1 14.1 1.6e-05 25.3 0.3 8.3 6 3 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32786.1 - 1.9e-12 47.1 12.4 0.0032 17.8 0.2 8.6 5 3 6 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32786.1 - 6.2e-09 35.4 10.2 11 6.9 0.0 9.9 10 1 1 11 11 11 2 Ankyrin repeat Ank PF00023.30 KDO32786.1 - 0.13 12.7 8.1 28 5.4 0.0 5.5 6 1 0 6 6 6 0 Ankyrin repeat RicinB_lectin_2 PF14200.6 KDO32787.1 - 0.0021 18.8 2.8 1.6 9.5 0.1 2.7 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like AAA_9 PF12781.7 KDO32787.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region Pkinase PF00069.25 KDO32788.1 - 4.8e-40 137.6 0.0 1.1e-39 136.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 KDO32788.1 - 2.2e-36 125.8 0.0 5.8e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 KDO32788.1 - 3.7e-15 55.9 0.0 8.3e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO32788.1 - 2.2e-05 23.9 0.0 4.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PP2C_2 PF13672.6 KDO32788.1 - 0.00012 21.8 0.0 0.00056 19.6 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C cNMP_binding PF00027.29 KDO32788.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ATP_bind_1 PF03029.17 KDO32789.1 - 8.3e-76 254.9 0.1 2e-75 253.7 0.1 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 KDO32789.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KDO32789.1 - 0.00062 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KDO32789.1 - 0.00078 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 KDO32789.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO32789.1 - 0.0015 19.1 0.1 0.011 16.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO32789.1 - 0.0021 18.5 0.0 0.093 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 KDO32789.1 - 0.004 16.8 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 KDO32789.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KDO32789.1 - 0.019 15.2 0.0 0.092 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KDO32789.1 - 0.024 14.2 0.0 0.16 11.6 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KDO32789.1 - 0.03 14.8 0.6 0.054 13.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 KDO32789.1 - 0.053 13.6 0.0 0.45 10.6 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KDO32789.1 - 0.059 12.6 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KDO32789.1 - 0.067 13.6 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KDO32789.1 - 0.072 13.5 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KDO32789.1 - 0.11 12.7 0.0 0.53 10.5 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_31 PF13614.6 KDO32789.1 - 0.11 12.3 0.0 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO32789.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KDO32789.1 - 0.16 11.9 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 KDO32789.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Choline_kinase PF01633.20 KDO32791.1 - 7e-47 159.8 0.0 1e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KDO32791.1 - 1.6e-07 31.5 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KDO32791.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain E1-E2_ATPase PF00122.20 KDO32793.1 - 4e-53 179.6 3.6 1.1e-52 178.2 1.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KDO32793.1 - 2.3e-49 167.6 3.6 2.3e-49 167.6 3.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KDO32793.1 - 4e-20 73.0 1.7 3.5e-18 66.6 1.7 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO32793.1 - 1.1e-19 70.4 0.1 2.7e-19 69.0 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KDO32793.1 - 3e-18 65.3 0.1 1.3e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO32793.1 - 8.4e-06 25.7 2.0 2.2e-05 24.3 2.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO32793.1 - 0.052 13.9 0.0 0.22 11.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase JTB PF05439.12 KDO32794.1 - 0.00012 22.1 0.4 0.00014 21.8 0.4 1.2 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) DUF4148 PF13663.6 KDO32794.1 - 0.025 14.7 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Antimicrobial10 PF08105.11 KDO32794.1 - 0.14 12.2 0.2 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Metchnikowin family bZIP_1 PF00170.21 KDO32795.1 - 0.074 13.2 12.3 0.67 10.1 1.3 3.2 3 0 0 3 3 3 0 bZIP transcription factor NRBF2 PF08961.10 KDO32795.1 - 0.15 11.6 15.8 1.3 8.6 0.6 3.2 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Rho_GDI PF02115.17 KDO32795.1 - 0.44 10.3 6.1 0.25 11.1 3.8 1.7 1 1 1 2 2 2 0 RHO protein GDP dissociation inhibitor YabA PF06156.13 KDO32795.1 - 0.56 10.9 22.0 0.81 10.4 2.4 3.4 2 2 1 3 3 3 0 Initiation control protein YabA DUF1904 PF08921.11 KDO32795.1 - 0.67 10.3 2.9 0.48 10.8 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) AAA_13 PF13166.6 KDO32795.1 - 1.6 7.3 18.0 1 7.9 15.8 1.5 1 1 1 2 2 2 0 AAA domain HALZ PF02183.18 KDO32795.1 - 1.7 8.9 15.2 0.4 10.9 0.5 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF773 PF05600.12 KDO32795.1 - 2.7 6.6 20.0 0.21 10.3 12.5 1.9 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 UPF0242 PF06785.11 KDO32795.1 - 3.8 7.6 24.1 0.94 9.5 19.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KDO32795.1 - 4.1 7.2 20.6 0.064 13.1 8.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KDO32795.1 - 4.2 7.5 33.6 80 3.4 30.2 2.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KDO32795.1 - 4.3 7.4 30.1 3.7 7.6 13.4 3.3 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Hrs_helical PF12210.8 KDO32795.1 - 6 7.5 16.9 2.1 8.9 1.2 3.6 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate APG6_N PF17675.1 KDO32795.1 - 6.4 7.3 37.7 7.1 7.2 6.6 3.4 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 KDO32795.1 - 6.5 6.0 23.5 4.8 6.4 12.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Glyco_transf_20 PF00982.21 KDO32796.1 - 3.3e-111 372.3 0.0 4.6e-111 371.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KDO32796.1 - 2.2e-54 184.1 0.0 3.9e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 KDO32796.1 - 4.1e-05 23.4 0.0 0.051 13.5 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain Hydrolase_3 PF08282.12 KDO32796.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PfkB PF00294.24 KDO32796.1 - 0.046 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Peptidase_S8 PF00082.22 KDO32797.1 - 2.9e-76 256.6 5.6 3.9e-76 256.2 4.4 1.8 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.8 KDO32797.1 - 6.8e-58 195.3 0.0 1.1e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II AAT PF03417.16 KDO32798.1 - 1.6e-26 93.4 0.1 2.2e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_S8 PF00082.22 KDO32799.1 - 4.4e-75 252.7 0.0 1.1e-74 251.4 0.0 1.7 1 1 1 2 2 2 1 Subtilase family TPPII PF12580.8 KDO32799.1 - 5.2e-52 176.1 0.0 8.9e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II CUE PF02845.16 KDO32801.1 - 2.2e-06 27.2 0.8 5.2e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 CUE domain Laminin_II PF06009.12 KDO32801.1 - 0.018 15.0 3.8 4.2 7.4 0.2 3.3 2 1 1 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 KDO32801.1 - 0.099 13.0 0.2 0.97 9.8 0.0 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1394 PF07159.12 KDO32802.1 - 1.1e-35 123.4 0.0 1.3e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Rad51 PF08423.11 KDO32803.1 - 4.1e-38 131.1 0.0 5.1e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KDO32803.1 - 3.5e-09 36.4 0.8 2.1e-08 33.8 0.7 2.2 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KDO32803.1 - 2.2e-08 33.9 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KDO32803.1 - 3.5e-05 23.4 0.3 0.00097 18.7 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KDO32803.1 - 0.0047 16.3 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain NACHT PF05729.12 KDO32803.1 - 0.026 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KDO32803.1 - 0.1 12.3 0.2 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KDO32803.1 - 0.11 12.7 0.1 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO32803.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 KDO32805.1 - 4.2e-41 141.1 0.1 4.2e-41 141.1 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KDO32805.1 - 7.5e-18 64.5 0.0 3.5e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KDO32805.1 - 0.0053 16.1 0.1 0.012 14.9 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1529 PF07485.11 KDO32805.1 - 0.022 14.7 0.3 0.043 13.7 0.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) DUF2974 PF11187.8 KDO32805.1 - 0.038 13.5 0.0 0.14 11.7 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) COesterase PF00135.28 KDO32805.1 - 0.23 10.3 0.1 2.6 6.8 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family WD40 PF00400.32 KDO32806.1 - 9.6e-45 149.7 15.2 1e-09 38.8 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO32806.1 - 2.1e-15 56.8 1.6 0.0022 18.3 0.4 5.7 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO32806.1 - 1.4e-06 27.3 7.9 0.24 10.0 0.1 4.8 2 2 2 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KDO32806.1 - 0.00024 20.2 0.8 0.001 18.1 0.0 2.4 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 KDO32806.1 - 0.0015 18.4 0.3 3.2 7.6 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Tox-SGS PF15651.6 KDO32806.1 - 0.0028 17.8 0.1 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 Salivary glad secreted protein domain toxin WD40_3 PF15911.5 KDO32806.1 - 0.0064 16.5 0.0 0.9 9.6 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KDO32806.1 - 0.0073 15.1 0.0 4.5 5.9 0.0 3.6 1 1 1 3 3 3 1 Nup133 N terminal like Hira PF07569.11 KDO32806.1 - 0.11 12.1 2.4 2.1 8.0 0.1 3.5 1 1 1 3 3 3 0 TUP1-like enhancer of split EF-hand_1 PF00036.32 KDO32807.1 - 1.6e-32 108.6 12.0 1.2e-09 37.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO32807.1 - 1.4e-28 99.1 7.3 8.1e-15 55.0 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO32807.1 - 8.5e-27 90.8 7.9 6e-10 38.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO32807.1 - 3e-20 70.7 11.5 1.9e-06 27.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KDO32807.1 - 6.2e-20 70.8 7.3 7e-09 35.4 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KDO32807.1 - 2.9e-10 40.3 0.2 5.2e-05 23.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KDO32807.1 - 1.1e-05 25.3 6.7 0.093 12.7 1.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KDO32807.1 - 0.00012 22.4 1.9 0.01 16.1 0.4 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO32807.1 - 0.00015 22.1 0.3 0.68 10.3 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 KDO32807.1 - 0.0071 16.3 0.5 1.8 8.5 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 KDO32807.1 - 0.011 15.6 2.6 0.37 10.7 0.8 2.7 1 1 1 2 2 2 0 SurA N-terminal domain AAA_assoc_C PF09821.9 KDO32807.1 - 0.021 15.3 0.1 3.3 8.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal AAA-associated domain PMBR PF09373.10 KDO32807.1 - 0.026 14.7 0.1 17 5.8 0.0 3.9 3 1 1 4 4 4 0 Pseudomurein-binding repeat IF2_N PF04760.15 KDO32807.1 - 0.041 13.7 1.8 17 5.3 0.0 3.8 3 1 1 4 4 4 0 Translation initiation factor IF-2, N-terminal region Acetyltransf_11 PF13720.6 KDO32807.1 - 0.044 14.2 0.1 0.69 10.4 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3349 PF11829.8 KDO32807.1 - 0.096 13.5 0.4 38 5.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) TerB PF05099.13 KDO32807.1 - 0.1 12.6 1.2 4.1 7.4 0.1 2.9 1 1 1 2 2 2 0 Tellurite resistance protein TerB LETM1 PF07766.13 KDO32807.1 - 0.1 11.9 0.9 0.84 8.9 0.7 2.1 1 1 2 3 3 3 0 LETM1-like protein FGAR-AT_linker PF18072.1 KDO32807.1 - 0.11 13.0 0.1 3 8.4 0.0 2.4 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF3008 PF11450.8 KDO32807.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.2 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) Ank PF00023.30 KDO32808.1 - 3e-17 62.2 15.8 5.5e-06 26.6 0.1 5.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KDO32808.1 - 6.1e-17 62.0 0.5 2.9e-08 34.2 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO32808.1 - 2.2e-14 53.3 6.7 8e-10 38.8 0.1 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO32808.1 - 2.3e-10 40.8 4.8 0.002 18.7 0.1 5.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32808.1 - 6.3e-08 32.3 7.1 0.00066 20.0 0.0 6.0 6 1 0 6 6 6 2 Ankyrin repeat PH PF00169.29 KDO32809.1 - 6.3e-20 71.7 0.1 7.1e-20 71.5 0.1 1.0 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 KDO32809.1 - 4.2e-06 26.8 0.0 5.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO32809.1 - 3e-05 24.4 1.6 0.0011 19.4 1.6 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KDO32809.1 - 4.3e-05 23.8 0.2 0.0027 18.1 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO32809.1 - 0.0018 18.5 0.0 0.0024 18.1 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KDO32809.1 - 0.0021 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KDO32809.1 - 0.0045 17.3 0.1 0.0067 16.8 0.1 1.5 1 1 0 1 1 1 1 Plant pleckstrin homology-like region PH_6 PF15406.6 KDO32809.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 KDO32809.1 - 0.023 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 PH domain Glyco_trans_1_2 PF13524.6 KDO32810.1 - 5.6e-09 36.3 0.0 1.8e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF111 PF01969.17 KDO32814.1 - 3e-108 362.2 0.0 3.4e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 AAR2 PF05282.11 KDO32815.1 - 2.2e-75 254.3 5.7 1.3e-73 248.4 5.7 2.0 1 1 0 1 1 1 1 AAR2 protein Tim44 PF04280.15 KDO32816.1 - 2.6e-29 102.2 0.4 2.6e-29 102.2 0.4 2.1 2 1 0 2 2 2 1 Tim44-like domain Lant_dehydr_C PF14028.6 KDO32816.1 - 0.075 12.6 5.6 0.15 11.5 5.6 1.5 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF883 PF05957.13 KDO32816.1 - 0.9 10.2 17.0 1.3 9.6 10.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3810 PF12725.7 KDO32816.1 - 2.5 7.3 4.8 28 3.9 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) D5_N PF08706.11 KDO32816.1 - 3.3 8.0 8.6 43 4.4 0.2 3.3 2 1 0 2 2 2 0 D5 N terminal like DUF763 PF05559.11 KDO32816.1 - 3.3 6.8 5.7 5.2 6.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) LETM1 PF07766.13 KDO32816.1 - 3.6 6.9 6.5 5.4 6.3 6.5 1.2 1 0 0 1 1 1 0 LETM1-like protein HSCB_C PF07743.13 KDO32816.1 - 4.4 7.9 11.4 3.9 8.0 8.8 2.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain HMG_box PF00505.19 KDO32816.1 - 7.6 7.0 11.0 0.75 10.3 5.7 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box ABC1 PF03109.16 KDO32818.1 - 5.8e-32 110.4 0.1 9.4e-32 109.7 0.1 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KDO32818.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KDO32818.1 - 0.078 12.9 0.3 0.23 11.4 0.3 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family GYF PF02213.16 KDO32821.1 - 9.2e-18 63.6 0.4 2e-17 62.5 0.4 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KDO32821.1 - 0.00013 21.7 0.1 0.00096 18.9 0.1 2.6 2 1 0 2 2 2 1 GYF domain 2 NiFe-hyd_HybE PF11939.8 KDO32821.1 - 0.0021 18.0 1.2 0.004 17.1 1.2 1.4 1 0 0 1 1 1 1 [NiFe]-hydrogenase assembly, chaperone, HybE Med15 PF09606.10 KDO32821.1 - 0.059 12.1 12.4 0.12 11.0 12.4 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal sCache_3_2 PF17203.4 KDO32821.1 - 0.074 13.2 2.5 0.13 12.4 2.5 1.4 1 0 0 1 1 1 0 Single cache domain 3 RCC1 PF00415.18 KDO32822.1 - 3.4e-102 334.9 27.7 1.1e-16 61.1 0.6 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO32822.1 - 6.4e-55 182.0 36.3 2.4e-10 39.9 1.1 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KDO32822.1 - 1.5e-18 67.0 1.6 6.3e-15 55.4 0.4 3.2 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KDO32822.1 - 1.2e-05 25.4 0.5 7.3e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1921 PF09081.10 KDO32822.1 - 0.0034 17.6 1.3 2 8.7 0.0 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1921) Peptidase_C58 PF03543.14 KDO32822.1 - 0.04 13.6 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF4213 PF13938.6 KDO32822.1 - 0.094 13.0 11.9 21 5.4 0.1 5.4 4 2 1 5 5 5 0 Putative heavy-metal chelation SUKH-3 PF14433.6 KDO32822.1 - 0.28 11.6 1.0 29 5.1 0.1 3.1 2 1 1 3 3 3 0 SUKH-3 immunity protein Syntaxin_2 PF14523.6 KDO32823.1 - 2.7e-14 53.4 6.1 1e-13 51.5 1.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KDO32823.1 - 9.9e-05 22.3 4.9 9.9e-05 22.3 4.9 2.3 2 1 0 2 2 2 1 SNARE domain TPP_enzyme_M PF00205.22 KDO32823.1 - 0.053 13.3 0.3 0.43 10.3 0.2 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Syntaxin PF00804.25 KDO32823.1 - 0.087 12.5 8.6 0.27 10.9 6.1 2.6 2 1 0 2 2 2 0 Syntaxin COG2 PF06148.11 KDO32823.1 - 0.1 12.7 2.4 1.8 8.7 0.1 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SIR2 PF02146.17 KDO32823.1 - 0.11 12.4 2.0 0.46 10.4 1.0 2.3 2 1 1 3 3 3 0 Sir2 family Baculo_PEP_C PF04513.12 KDO32823.1 - 0.3 11.1 5.2 3.5 7.7 0.4 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KDO32823.1 - 0.63 10.0 6.6 2.1 8.4 0.2 3.0 2 1 1 3 3 3 0 Laminin Domain II IL15 PF02372.15 KDO32823.1 - 0.7 9.9 4.5 5.8 6.9 1.1 2.9 2 1 0 2 2 2 0 Interleukin 15 Synaptobrevin PF00957.21 KDO32823.1 - 0.99 9.2 6.5 2.6 7.9 2.8 3.0 2 1 0 2 2 2 0 Synaptobrevin SKA1 PF07160.12 KDO32823.1 - 1.1 9.1 6.6 0.38 10.6 0.6 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Mer2 PF09074.10 KDO32823.1 - 3.9 7.2 8.7 2.5 7.8 6.1 1.9 1 1 1 2 2 2 0 Mer2 Myosin_head PF00063.21 KDO32824.1 - 1.8e-216 720.5 2.5 1.8e-216 720.5 2.5 1.8 2 1 1 3 3 3 1 Myosin head (motor domain) WW PF00397.26 KDO32824.1 - 2e-09 37.3 0.0 4.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 WW domain IQ PF00612.27 KDO32824.1 - 0.00015 21.2 19.2 0.054 13.3 0.3 5.7 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_22 PF13401.6 KDO32824.1 - 0.014 15.6 0.1 0.14 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO32824.1 - 0.016 15.6 1.1 0.18 12.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Myosin_N PF02736.19 KDO32824.1 - 0.43 10.5 7.2 0.027 14.3 0.9 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain bZIP_1 PF00170.21 KDO32824.1 - 2.6 8.2 16.1 0.23 11.6 2.1 3.7 3 0 0 3 3 3 0 bZIP transcription factor DUF4094 PF13334.6 KDO32826.1 - 0.072 13.5 2.0 0.073 13.5 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) XkdW PF09636.10 KDO32826.1 - 1.8 8.7 4.1 1.5 8.9 0.5 2.4 1 1 2 3 3 3 0 XkdW protein DASH_Dad2 PF08654.10 KDO32826.1 - 3.1 8.3 8.5 1.2 9.6 0.5 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad2 Thioredoxin_8 PF13905.6 KDO32827.1 - 1.2e-50 169.8 0.0 2e-29 101.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KDO32827.1 - 4.6e-14 52.4 0.0 1.6e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KDO32827.1 - 5.6e-14 52.1 0.0 1.2e-08 34.9 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 KDO32827.1 - 1e-11 44.7 0.1 2.8e-07 30.5 0.0 3.6 2 2 2 4 4 4 2 Thioredoxin Thioredoxin_2 PF13098.6 KDO32827.1 - 9.1e-10 39.0 0.0 9.3e-09 35.7 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain ZZ PF00569.17 KDO32827.1 - 3.9e-06 26.6 2.7 8e-06 25.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Thioredoxin_7 PF13899.6 KDO32827.1 - 0.00014 21.9 0.0 0.0034 17.5 0.0 2.9 3 1 0 3 3 3 1 Thioredoxin-like SCO1-SenC PF02630.14 KDO32827.1 - 0.00079 19.3 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 SCO1/SenC TraF PF13728.6 KDO32827.1 - 0.0096 15.8 0.0 0.092 12.6 0.0 2.4 2 1 0 2 2 2 1 F plasmid transfer operon protein C1_2 PF03107.16 KDO32827.1 - 0.014 15.7 3.8 0.037 14.3 3.8 1.7 1 0 0 1 1 1 0 C1 domain Ank_2 PF12796.7 KDO32828.1 - 8.7e-40 135.2 2.1 3.9e-16 59.4 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32828.1 - 1.7e-31 108.2 9.1 1.8e-08 34.7 0.1 6.9 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32828.1 - 3.5e-24 84.5 10.2 6.6e-07 29.5 0.2 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO32828.1 - 2.1e-21 75.4 15.1 0.00019 21.7 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 KDO32828.1 - 1.8e-18 64.7 5.1 0.00071 19.8 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat WW PF00397.26 KDO32828.1 - 6.7e-07 29.3 1.4 1.4e-06 28.3 1.4 1.5 1 0 0 1 1 1 1 WW domain Pkinase PF00069.25 KDO32829.1 - 1.7e-33 116.1 0.0 3.4e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32829.1 - 3.9e-31 108.3 0.0 5.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO32829.1 - 3.4e-05 22.8 0.0 4.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO32829.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO32829.1 - 0.052 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.17 KDO32830.1 - 1.2e-60 204.4 0.0 1.8e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family DUF4164 PF13747.6 KDO32830.1 - 0.042 14.1 1.4 0.042 14.1 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) BRE1 PF08647.11 KDO32830.1 - 0.38 10.8 2.1 3.8 7.7 0.4 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase WW PF00397.26 KDO32831.1 - 4e-20 71.6 0.9 1.9e-09 37.4 0.2 2.4 2 0 0 2 2 2 2 WW domain ATG16 PF08614.11 KDO32831.1 - 0.01 16.1 2.1 0.01 16.1 2.1 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KDO32831.1 - 0.011 15.8 0.8 0.021 14.9 0.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 KDO32831.1 - 0.018 15.7 0.3 0.03 14.9 0.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KDO32831.1 - 0.026 15.0 0.8 0.044 14.2 0.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Herpes_BLRF2 PF05812.12 KDO32831.1 - 0.03 14.5 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein ADIP PF11559.8 KDO32831.1 - 0.12 12.5 0.6 0.17 12.0 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KDO32831.1 - 0.13 12.6 0.3 0.23 11.8 0.3 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 KDO32831.1 - 0.26 11.1 3.7 0.46 10.3 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 KDO32831.1 - 0.37 10.9 2.6 0.62 10.2 2.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper WW PF00397.26 KDO32832.1 - 9.6e-11 41.6 3.1 3.7e-09 36.5 0.9 2.3 2 0 0 2 2 2 2 WW domain IQ PF00612.27 KDO32832.1 - 0.054 13.3 4.4 0.96 9.4 1.0 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif ZapB PF06005.12 KDO32833.1 - 0.0029 18.0 0.8 0.0045 17.4 0.8 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 KDO32833.1 - 0.02 14.6 1.4 0.038 13.8 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Utp14 PF04615.13 KDO32833.1 - 0.53 8.8 10.1 0.65 8.5 10.1 1.0 1 0 0 1 1 1 0 Utp14 protein ATG16 PF08614.11 KDO32834.1 - 0.00057 20.2 7.8 0.00074 19.8 1.4 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 KDO32834.1 - 0.013 15.3 1.2 0.03 14.1 1.0 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF2968 PF11180.8 KDO32834.1 - 0.026 14.2 5.7 0.21 11.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) MbeD_MobD PF04899.12 KDO32834.1 - 0.043 13.9 2.5 0.13 12.3 2.5 1.8 1 1 0 1 1 1 0 MbeD/MobD like Com_YlbF PF06133.11 KDO32834.1 - 0.057 14.0 2.3 0.087 13.4 1.0 1.7 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA SlyX PF04102.12 KDO32834.1 - 0.067 13.8 5.2 4.4 8.0 2.2 2.3 2 1 0 2 2 2 0 SlyX CCDC53 PF10152.9 KDO32834.1 - 0.072 13.5 0.8 0.085 13.3 0.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GIT_CC PF16559.5 KDO32834.1 - 0.08 12.8 0.7 7.2 6.6 0.2 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KDO32834.1 - 0.33 10.8 3.5 0.62 9.9 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.6 KDO32834.1 - 0.43 10.1 4.3 0.43 10.1 1.4 1.9 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 bZIP_2 PF07716.15 KDO32834.1 - 2.1 8.5 7.4 5.5 7.2 1.0 2.8 3 0 0 3 3 3 0 Basic region leucine zipper I_LWEQ PF01608.17 KDO32835.1 - 0.0077 16.5 0.2 0.0095 16.2 0.2 1.0 1 0 0 1 1 1 1 I/LWEQ domain SNARE PF05739.19 KDO32835.1 - 0.37 10.8 0.8 0.69 10.0 0.2 1.7 2 0 0 2 2 2 0 SNARE domain Thioredoxin_8 PF13905.6 KDO32836.1 - 6.9e-50 167.3 0.0 5e-29 100.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KDO32836.1 - 8.1e-14 51.6 0.0 5.1e-09 36.1 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KDO32836.1 - 3.2e-13 49.6 0.0 2.5e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.20 KDO32836.1 - 1.4e-11 44.3 0.1 2.4e-07 30.7 0.0 3.4 2 2 2 4 4 4 2 Thioredoxin Thioredoxin_2 PF13098.6 KDO32836.1 - 7.7e-10 39.2 0.0 9.4e-09 35.7 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain ZZ PF00569.17 KDO32836.1 - 1.8e-05 24.5 2.2 3.6e-05 23.5 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Thioredoxin_7 PF13899.6 KDO32836.1 - 0.00018 21.6 0.0 0.0043 17.2 0.0 2.8 3 1 0 3 3 3 1 Thioredoxin-like SCO1-SenC PF02630.14 KDO32836.1 - 0.0014 18.6 0.0 0.09 12.7 0.0 2.4 2 0 0 2 2 2 1 SCO1/SenC TraF PF13728.6 KDO32836.1 - 0.014 15.2 0.0 0.087 12.6 0.0 2.2 2 1 0 2 2 2 0 F plasmid transfer operon protein C1_2 PF03107.16 KDO32836.1 - 0.038 14.3 3.3 0.1 12.9 3.3 1.7 1 0 0 1 1 1 0 C1 domain HyaE PF07449.11 KDO32836.1 - 0.078 12.9 0.0 1.4 8.9 0.0 2.7 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE bZIP_1 PF00170.21 KDO32837.1 - 0.006 16.6 5.9 1.1 9.4 0.1 3.6 3 0 0 3 3 3 2 bZIP transcription factor DUF4094 PF13334.6 KDO32837.1 - 0.11 12.9 0.5 0.11 12.9 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) BBP1_C PF15272.6 KDO32837.1 - 0.28 11.0 5.3 1.9 8.3 0.3 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal XkdW PF09636.10 KDO32837.1 - 4.9 7.3 5.3 3.6 7.7 0.4 2.8 2 1 1 3 3 3 0 XkdW protein WW PF00397.26 KDO32838.1 - 4.5e-10 39.4 0.0 7.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 WW domain Gam PF06064.11 KDO32838.1 - 0.073 13.3 0.9 0.18 12.0 0.6 1.8 2 0 0 2 2 2 0 Host-nuclease inhibitor protein Gam bZIP_2 PF07716.15 KDO32838.1 - 1.3 9.1 5.8 3.1 7.9 2.0 3.2 2 1 1 3 3 3 0 Basic region leucine zipper Mito_fiss_reg PF05308.11 KDO32838.1 - 5.9 6.9 19.5 13 5.7 9.2 3.1 1 1 1 2 2 2 0 Mitochondrial fission regulator Thioredoxin_8 PF13905.6 KDO32839.1 - 1.3e-34 118.4 0.0 3.1e-21 75.5 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KDO32839.1 - 2e-09 37.5 0.0 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KDO32839.1 - 1.1e-08 35.5 0.0 2.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 KDO32839.1 - 7.2e-07 29.1 0.0 0.0081 16.1 0.0 3.6 2 1 1 3 3 3 2 Thioredoxin ZZ PF00569.17 KDO32839.1 - 2.1e-06 27.4 3.6 5.7e-06 26.0 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KDO32839.1 - 0.00023 21.4 1.5 0.00023 21.4 1.5 2.0 2 0 0 2 2 2 1 C1 domain Thioredoxin_7 PF13899.6 KDO32839.1 - 0.0015 18.7 0.1 0.0091 16.2 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KDO32839.1 - 0.011 15.6 0.0 0.048 13.5 0.0 2.0 2 1 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.11 KDO32839.1 - 0.1 12.6 0.0 3.5 7.6 0.0 2.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF2407_C PF13373.6 KDO32841.1 - 7.6e-23 81.2 0.1 1.1e-22 80.7 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 KDO32841.1 - 4.4e-12 45.6 0.0 7.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KDO32841.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO32841.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF456 PF04306.13 KDO32841.1 - 0.026 14.8 0.9 0.041 14.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Ubiquitin_4 PF18036.1 KDO32841.1 - 0.086 12.9 0.1 2.6 8.2 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain NADHdh_A3 PF14987.6 KDO32842.1 - 0.0021 18.3 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 IQ PF00612.27 KDO32843.1 - 0.038 13.8 3.3 0.1 12.4 3.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Arm PF00514.23 KDO32844.1 - 1.5e-91 298.0 19.6 3.5e-12 45.9 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KDO32844.1 - 1.2e-29 102.3 4.6 7e-11 42.4 0.0 6.4 5 1 2 7 7 7 6 HEAT-like repeat Arm_3 PF16186.5 KDO32844.1 - 5.7e-20 70.6 0.1 2.2e-18 65.5 1.1 2.6 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_2 PF13646.6 KDO32844.1 - 7.8e-20 71.1 0.1 0.00012 22.4 0.0 5.6 2 2 5 7 7 7 6 HEAT repeats HEAT PF02985.22 KDO32844.1 - 2.1e-19 67.9 4.5 0.00036 20.6 0.0 9.2 9 0 0 9 9 9 3 HEAT repeat IBB PF01749.20 KDO32844.1 - 6.2e-11 42.6 0.1 3e-10 40.4 0.2 2.1 2 0 0 2 2 2 1 Importin beta binding domain V-ATPase_H_C PF11698.8 KDO32844.1 - 5e-08 33.1 0.1 0.052 13.7 0.0 4.9 4 3 0 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.20 KDO32844.1 - 5.9e-07 28.4 0.1 0.0003 19.5 0.0 3.1 1 1 2 3 3 3 1 Adaptin N terminal region NopRA1 PF16201.5 KDO32844.1 - 1.6e-06 27.9 0.0 0.25 10.9 0.0 3.8 3 1 0 3 3 3 2 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.16 KDO32844.1 - 1.9e-06 28.0 0.8 2.1 9.3 0.0 6.5 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KDO32844.1 - 2.7e-06 27.5 0.0 1.1 9.2 0.0 3.7 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 KDO32844.1 - 5.1e-06 26.6 0.4 0.13 12.5 0.0 4.9 4 1 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KDO32844.1 - 1.3e-05 24.8 0.0 0.93 8.9 0.1 3.5 1 1 2 3 3 3 3 Armadillo-like IFRD PF05004.13 KDO32844.1 - 0.00013 21.2 0.9 9 5.3 0.0 4.2 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) SEN1_N PF12726.7 KDO32844.1 - 0.00047 18.5 0.3 0.32 9.2 0.0 3.6 4 0 0 4 4 4 1 SEN1 N terminal CTNNBL PF08216.11 KDO32844.1 - 0.008 16.3 1.3 0.74 10.0 0.0 4.1 5 0 0 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 KDO32844.1 - 0.0081 16.2 0.0 3.4 7.7 0.0 3.0 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Mo25 PF08569.11 KDO32844.1 - 0.0085 15.5 0.0 0.69 9.2 0.0 2.7 3 0 0 3 3 3 1 Mo25-like ParcG PF10274.9 KDO32844.1 - 0.018 15.2 0.5 4.1 7.5 0.0 3.2 2 1 1 3 3 3 0 Parkin co-regulated protein DUF3523 PF12037.8 KDO32845.1 - 6e-92 307.8 25.2 9.1e-92 307.2 25.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KDO32845.1 - 1.3e-22 80.6 0.0 2.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO32845.1 - 3.7e-05 24.2 8.1 0.0006 20.2 0.2 3.8 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KDO32845.1 - 9.7e-05 22.2 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KDO32845.1 - 0.0014 18.6 0.2 0.013 15.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO32845.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KDO32845.1 - 0.0034 17.2 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KDO32845.1 - 0.0044 16.4 0.2 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KDO32845.1 - 0.0067 16.7 8.2 0.017 15.4 0.0 3.3 2 2 1 4 4 4 1 AAA domain TsaE PF02367.17 KDO32845.1 - 0.012 15.6 0.0 0.043 13.8 0.0 2.0 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KDO32845.1 - 0.017 15.7 0.1 0.017 15.7 0.1 3.4 2 2 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KDO32845.1 - 0.022 14.5 0.0 0.08 12.7 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO32845.1 - 0.051 14.0 0.6 0.14 12.6 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Sigma54_activ_2 PF14532.6 KDO32845.1 - 0.068 13.3 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KDO32845.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.1 3 1 0 3 3 2 0 AAA domain Ribosomal_L31e PF01198.19 KDO32846.1 - 3.1e-42 142.7 1.9 4.2e-42 142.3 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CEP1-DNA_bind PF09287.10 KDO32846.1 - 0.026 14.2 0.2 0.13 11.8 0.2 2.0 1 1 0 1 1 1 0 CEP-1, DNA binding Vsr PF03852.15 KDO32846.1 - 0.042 13.7 0.1 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 DNA mismatch endonuclease Vsr B1 PF02246.15 KDO32846.1 - 0.34 11.0 3.9 3.5 7.7 0.1 2.9 2 1 1 3 3 3 0 Protein L b1 domain tRNA-synt_2 PF00152.20 KDO32847.1 - 1.9e-101 339.3 0.0 2.3e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KDO32847.1 - 2.4e-14 53.1 0.0 5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 KDO32847.1 - 1.2e-07 31.8 0.1 2.1e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 KDO32847.1 - 0.015 14.8 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Met_synt_B12 PF02965.17 KDO32848.1 - 1e-112 376.1 0.0 1.9e-112 375.2 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 KDO32848.1 - 7.6e-76 255.4 0.2 4.7e-75 252.8 0.0 2.2 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 KDO32848.1 - 3.2e-51 174.3 1.3 4.5e-51 173.9 0.4 1.8 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 KDO32848.1 - 1.1e-23 83.4 0.1 1.1e-23 83.4 0.1 2.6 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 KDO32848.1 - 1.2e-16 60.8 0.4 4.4e-16 59.0 0.4 2.0 1 0 0 1 1 1 1 B12 binding domain FUN14 PF04930.15 KDO32851.1 - 3e-24 85.2 3.4 4.9e-24 84.6 3.4 1.3 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.32 KDO32851.1 - 1.8e-05 24.0 0.3 4.4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KDO32851.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KDO32851.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KDO32851.1 - 0.079 12.5 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 EF hand Ndc1_Nup PF09531.10 KDO32852.1 - 0.66 8.6 7.3 0.95 8.1 7.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IFT57 PF10498.9 KDO32853.1 - 6.3e-108 361.0 7.8 7.3e-108 360.8 7.8 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 APG17 PF04108.12 KDO32853.1 - 0.00084 18.6 5.5 0.0012 18.1 5.5 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 YojJ PF10372.9 KDO32853.1 - 0.0028 17.7 3.8 0.012 15.7 0.4 2.6 2 0 0 2 2 2 1 Bacterial membrane-spanning protein N-terminus MscS_porin PF12795.7 KDO32853.1 - 0.0034 17.0 4.4 0.0057 16.2 4.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 KDO32853.1 - 0.0093 15.3 7.2 0.016 14.6 7.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 KDO32853.1 - 0.02 15.6 1.5 0.02 15.6 1.5 2.6 2 1 1 3 3 3 0 Occludin homology domain Sec34 PF04136.15 KDO32853.1 - 0.04 13.8 4.4 0.051 13.5 2.6 2.0 1 1 1 2 2 2 0 Sec34-like family Spectrin PF00435.21 KDO32853.1 - 0.15 12.6 10.0 0.055 14.0 5.1 2.3 2 0 0 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 KDO32853.1 - 0.28 11.2 9.4 1.1 9.3 5.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF922 PF06037.11 KDO32853.1 - 0.29 10.9 5.5 0.17 11.7 2.6 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF922) Med30 PF11315.8 KDO32853.1 - 0.31 11.3 13.9 3.6 7.8 0.8 3.5 1 1 2 3 3 3 0 Mediator complex subunit 30 Allexi_40kDa PF05549.11 KDO32853.1 - 0.34 10.4 7.2 0.59 9.6 7.0 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 KDO32853.1 - 0.37 10.8 4.9 4.7 7.3 2.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 KDO32853.1 - 0.47 9.7 8.0 0.26 10.5 5.7 1.6 1 1 1 2 2 2 0 TMPIT-like protein Spc7 PF08317.11 KDO32853.1 - 0.93 8.3 18.5 0.034 13.0 11.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KDO32853.1 - 1.3 8.8 8.9 0.33 10.8 2.7 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.12 KDO32853.1 - 1.6 8.8 9.5 5.1 7.1 1.3 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF148 PF02520.17 KDO32853.1 - 1.7 8.7 9.4 0.87 9.7 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF2408 PF10303.9 KDO32853.1 - 2.9 8.5 9.6 3.5 8.2 7.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF948 PF06103.11 KDO32853.1 - 3.3 8.0 7.4 12 6.3 1.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 KDO32853.1 - 3.5 8.4 8.0 1.9 9.2 0.8 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Nup54 PF13874.6 KDO32853.1 - 4.3 7.5 7.8 18 5.5 7.7 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FTA4 PF13093.6 KDO32853.1 - 5.1 6.9 9.9 45 3.9 9.8 2.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prominin PF05478.11 KDO32853.1 - 5.2 4.9 8.0 7.7 4.3 7.4 1.5 1 1 0 1 1 1 0 Prominin DUF4446 PF14584.6 KDO32853.1 - 5.3 7.0 7.3 4.8 7.2 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) KxDL PF10241.9 KDO32853.1 - 6.6 7.1 7.6 29 5.0 4.0 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein DeoC PF01791.9 KDO32854.1 - 4.8e-16 59.1 1.0 5.8e-16 58.8 1.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 KDO32854.1 - 0.0067 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 KDO32854.1 - 0.032 13.4 0.7 0.057 12.6 0.6 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase TPR_19 PF14559.6 KDO32857.1 - 2.9e-06 27.7 6.4 0.067 13.7 0.0 4.1 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KDO32857.1 - 1.7 9.0 5.0 0.78 10.1 0.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat HTH_35 PF13693.6 KDO32858.1 - 0.007 16.4 0.3 0.041 13.9 0.0 2.0 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding TPR_21 PF09976.9 KDO32858.1 - 0.0085 15.8 5.3 0.43 10.3 1.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain ParE_toxin PF05016.15 KDO32858.1 - 0.037 14.6 1.6 0.94 10.1 0.2 2.1 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE DUF2742 PF10888.8 KDO32858.1 - 0.071 13.4 1.6 0.42 10.9 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2742) Lipocalin_7 PF14651.6 KDO32859.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Ufd2P_core PF10408.9 KDO32860.1 - 6.9e-157 523.8 0.0 8.4e-157 523.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KDO32860.1 - 4.4e-26 90.8 0.1 1.5e-25 89.2 0.1 2.0 1 0 0 1 1 1 1 U-box domain Chitin_synth_1 PF01644.17 KDO32861.1 - 9.9e-32 110.2 0.0 2e-17 63.6 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.15 KDO32861.1 - 2.5e-23 82.5 1.3 3.5e-19 68.8 0.1 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KDO32861.1 - 2.7e-12 47.0 1.4 2.7e-12 47.0 1.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Chitin_synth_1N PF08407.11 KDO32861.1 - 4.4e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.6 KDO32861.1 - 5e-07 29.8 0.0 9.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KDO32861.1 - 0.0078 15.7 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Pkinase PF00069.25 KDO32862.1 - 2.9e-71 239.9 0.0 3.4e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO32862.1 - 4.9e-27 94.8 0.0 6.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO32862.1 - 0.00029 19.9 0.0 0.0022 17.0 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO32862.1 - 0.0016 17.8 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KDO32862.1 - 0.0062 16.5 0.0 0.022 14.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO32862.1 - 0.053 12.9 0.1 0.15 11.4 0.0 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO32862.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KDO32862.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RPN6_N PF18055.1 KDO32863.1 - 1.1e-27 96.7 1.0 6.1e-27 94.3 0.0 2.4 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KDO32863.1 - 1.5e-18 67.2 6.0 3.1e-17 63.0 0.2 3.0 2 1 0 2 2 2 2 PCI domain RPN6_C_helix PF18503.1 KDO32863.1 - 5.9e-10 38.7 0.3 1e-08 34.7 0.0 2.8 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KDO32863.1 - 0.0022 17.4 4.2 0.0042 16.5 3.9 1.6 1 1 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 KDO32863.1 - 0.04 14.0 6.4 2.3 8.4 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DDRGK PF09756.9 KDO32863.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 DDRGK domain PA28_beta PF02252.18 KDO32865.1 - 2.4e-28 98.6 0.1 5.1e-20 71.6 0.1 2.1 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Myb_CC_LHEQLE PF14379.6 KDO32865.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Peripla_BP_2 PF01497.18 KDO32866.1 - 1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein Med26 PF08711.11 KDO32868.1 - 1.8e-12 47.1 0.5 4.9e-12 45.7 0.5 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DEK_C PF08766.11 KDO32868.1 - 7.3e-05 22.6 1.3 7.3e-05 22.6 1.3 1.8 2 0 0 2 2 2 1 DEK C terminal domain D5_N PF08706.11 KDO32868.1 - 0.068 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 D5 N terminal like DUF1515 PF07439.11 KDO32868.1 - 1.6 8.8 5.5 0.36 10.9 0.9 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1515) TFCD_C PF12612.8 KDO32869.1 - 1e-43 149.4 0.6 5.6e-42 143.7 0.0 3.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KDO32869.1 - 1e-05 25.8 15.3 0.33 11.4 0.1 6.9 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KDO32869.1 - 0.0019 18.3 23.3 0.62 10.5 0.0 9.0 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 KDO32869.1 - 0.0029 17.7 0.4 28 4.7 0.0 5.2 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KDO32869.1 - 0.0035 16.6 0.2 0.26 10.4 0.0 3.5 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_PBS PF03130.16 KDO32869.1 - 0.0063 17.1 6.4 32 5.6 0.0 6.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KDO32869.1 - 0.021 15.3 18.1 2.3 8.8 0.0 8.3 6 2 3 9 9 9 0 HEAT-like repeat Coprogen_oxidas PF01218.18 KDO32870.1 - 4.6e-133 442.5 0.0 5.4e-133 442.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Aminotran_5 PF00266.19 KDO32872.1 - 1.4e-32 113.0 0.1 4.9e-19 68.5 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V MOSC PF03473.17 KDO32872.1 - 2.1e-31 108.7 0.0 3.8e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KDO32872.1 - 1.4e-15 57.2 0.0 2.9e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Opiods_neuropep PF01160.18 KDO32872.1 - 0.027 14.6 0.1 0.09 12.9 0.1 1.9 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide AP3D1 PF06375.11 KDO32873.1 - 1.8 8.8 4.4 2.9 8.1 4.4 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PRKCSH PF07915.13 KDO32874.1 - 6.9e-15 55.8 0.5 1.9e-14 54.4 0.2 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KDO32874.1 - 2.6e-05 23.9 0.0 0.0001 22.0 0.0 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein AAA_12 PF13087.6 KDO32876.1 - 6.6e-45 153.2 0.0 1.8e-44 151.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KDO32876.1 - 2.8e-27 96.1 8.5 2.8e-15 56.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain DNA_pol_A_exo1 PF01612.20 KDO32876.1 - 2.4e-14 53.4 0.1 4.1e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease AAA_30 PF13604.6 KDO32876.1 - 4e-14 52.8 0.2 1.7e-13 50.7 0.2 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO32876.1 - 1.2e-12 48.3 0.1 6.4e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KDO32876.1 - 2.9e-06 27.4 0.0 5.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KDO32876.1 - 4.7e-06 26.3 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KDO32876.1 - 6.6e-05 22.3 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 KDO32876.1 - 0.00018 21.4 0.1 0.00077 19.4 0.1 2.2 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.6 KDO32876.1 - 0.0073 16.6 0.0 0.031 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO32876.1 - 0.024 15.0 0.8 0.18 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain PhoH PF02562.16 KDO32876.1 - 0.03 13.8 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KDO32876.1 - 0.043 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KDO32876.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.6 KDO32876.1 - 0.052 12.9 0.0 4 6.7 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KDO32876.1 - 0.073 12.9 3.9 0.18 11.7 0.2 3.3 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain CENP-B_dimeris PF09026.10 KDO32876.1 - 1.9 8.9 17.1 4.9 7.6 17.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_1 PF00561.20 KDO32877.1 - 1.6e-21 77.1 0.0 7e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO32877.1 - 1.8e-17 63.4 0.0 8.5e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO32877.1 - 1.9e-17 64.6 3.2 1.9e-17 64.6 3.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KDO32877.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KDO32877.1 - 0.00032 19.5 0.0 0.00047 18.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KDO32877.1 - 0.00047 19.9 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KDO32877.1 - 0.0005 19.5 0.0 0.0014 18.0 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 KDO32877.1 - 0.00081 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KDO32877.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase Palm_thioest PF02089.15 KDO32877.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 KDO32877.1 - 0.012 15.4 0.0 0.039 13.7 0.0 1.8 1 1 1 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 KDO32877.1 - 0.029 14.5 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain LIDHydrolase PF10230.9 KDO32877.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 KDO32877.1 - 0.06 12.3 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme RHD3 PF05879.12 KDO32879.1 - 0.0011 17.2 3.0 0.0017 16.6 0.0 2.1 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 KDO32879.1 - 0.019 15.0 2.0 0.07 13.2 0.1 2.6 2 2 1 3 3 3 0 Dynamin family Ank_2 PF12796.7 KDO32880.1 - 8.4e-44 148.1 4.9 2.1e-13 50.7 0.3 5.5 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) AAA PF00004.29 KDO32880.1 - 2.8e-33 115.1 0.1 3.7e-12 46.8 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) Ank PF00023.30 KDO32880.1 - 7.2e-31 105.3 8.9 1.3e-05 25.4 0.4 8.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KDO32880.1 - 3.8e-26 91.1 0.4 2.5e-09 37.5 0.2 6.4 4 2 3 7 7 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32880.1 - 1.1e-24 86.2 6.3 5.3e-08 33.0 0.2 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32880.1 - 1.1e-23 80.7 0.0 0.00058 20.1 0.0 8.7 9 0 0 9 9 8 4 Ankyrin repeat AAA_lid_6 PF17866.1 KDO32880.1 - 8.5e-15 54.7 0.1 0.00069 19.7 0.0 4.0 3 0 0 3 3 3 3 AAA lid domain AAA_22 PF13401.6 KDO32880.1 - 2.2e-11 44.2 4.3 0.13 12.5 0.1 6.4 3 3 1 4 4 4 3 AAA domain AAA_5 PF07728.14 KDO32880.1 - 3.9e-10 39.9 0.5 0.022 14.7 0.1 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KDO32880.1 - 4.9e-09 35.9 1.7 0.017 14.5 0.0 5.0 3 2 2 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KDO32880.1 - 3e-08 33.9 0.3 0.17 12.1 0.0 4.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KDO32880.1 - 3e-08 33.7 0.1 0.21 11.3 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KDO32880.1 - 3.2e-08 33.5 9.6 0.0048 16.6 0.2 4.1 4 0 0 4 4 3 3 AAA domain RuvB_N PF05496.12 KDO32880.1 - 3.7e-08 33.3 0.2 0.034 13.9 0.0 3.6 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 KDO32880.1 - 9.4e-08 31.7 0.0 0.12 11.7 0.1 4.7 3 2 1 4 4 4 2 Bacterial TniB protein AAA_16 PF13191.6 KDO32880.1 - 1.9e-07 31.6 8.7 0.011 16.1 0.0 4.9 5 0 0 5 5 3 2 AAA ATPase domain AAA_18 PF13238.6 KDO32880.1 - 3.3e-07 30.9 0.3 0.21 12.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KDO32880.1 - 4.9e-07 29.6 3.7 0.066 12.9 0.0 5.6 3 3 1 4 4 4 1 Sigma-54 interaction domain NACHT PF05729.12 KDO32880.1 - 2.8e-06 27.3 0.1 0.012 15.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 KDO32880.1 - 5.8e-06 26.7 0.0 1.7 9.1 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_24 PF13479.6 KDO32880.1 - 6.3e-06 26.0 0.2 0.46 10.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 KDO32880.1 - 6.5e-06 26.3 0.1 0.25 11.4 0.0 3.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_2 PF07724.14 KDO32880.1 - 6.9e-06 26.3 0.0 0.12 12.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KDO32880.1 - 2.7e-05 23.8 0.2 0.5 9.9 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region CbiA PF01656.23 KDO32880.1 - 0.00013 22.0 1.2 2.1 8.4 0.0 3.7 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 KDO32880.1 - 0.00037 20.8 10.0 0.069 13.4 0.1 4.9 5 1 0 5 5 3 1 AAA domain ABC_tran PF00005.27 KDO32880.1 - 0.00038 21.0 0.1 8.7 6.9 0.0 4.2 4 1 0 4 4 3 0 ABC transporter ResIII PF04851.15 KDO32880.1 - 0.00061 19.8 1.4 0.15 12.0 0.0 3.7 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KDO32880.1 - 0.00062 20.2 0.3 0.53 10.7 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 KDO32880.1 - 0.001 18.9 0.5 2.1 8.2 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KDO32880.1 - 0.001 18.8 0.7 8.7 6.0 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF2075 PF09848.9 KDO32880.1 - 0.0015 17.8 4.3 5.7 6.1 0.0 4.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KDO32880.1 - 0.0026 17.5 0.1 18 5.2 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain TsaE PF02367.17 KDO32880.1 - 0.0037 17.3 4.7 0.68 9.9 0.0 3.6 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 KDO32880.1 - 0.0041 17.2 0.0 4.6 7.3 0.0 3.0 3 0 0 3 3 2 0 Torsin SRP54 PF00448.22 KDO32880.1 - 0.0053 16.4 2.0 2.6 7.6 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain PhoH PF02562.16 KDO32880.1 - 0.009 15.5 2.3 6.2 6.2 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein ATPase PF06745.13 KDO32880.1 - 0.0096 15.3 0.2 2.6 7.3 0.0 3.2 3 0 0 3 3 3 1 KaiC PRK PF00485.18 KDO32880.1 - 0.016 14.9 0.5 4.7 6.9 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 KDO32880.1 - 0.021 14.7 0.2 36 4.2 0.0 3.6 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 KDO32880.1 - 0.028 14.8 15.7 3 8.2 0.1 5.3 4 2 2 6 6 4 0 AAA domain KTI12 PF08433.10 KDO32880.1 - 0.047 13.1 0.1 8.3 5.8 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 CoaE PF01121.20 KDO32880.1 - 0.097 12.3 1.2 4.8 6.8 0.0 3.6 4 0 0 4 4 3 0 Dephospho-CoA kinase SKI PF01202.22 KDO32880.1 - 0.1 12.7 0.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase APS_kinase PF01583.20 KDO32880.1 - 0.11 12.4 3.4 14 5.5 0.0 3.7 4 0 0 4 4 4 0 Adenylylsulphate kinase T2SSE PF00437.20 KDO32880.1 - 0.11 11.6 0.0 5.4 6.0 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KDO32880.1 - 0.11 11.8 0.0 22 4.2 0.0 3.5 4 0 0 4 4 4 0 Zeta toxin AAA_11 PF13086.6 KDO32880.1 - 0.16 11.7 3.6 15 5.3 0.0 3.8 4 0 0 4 4 3 0 AAA domain TrwB_AAD_bind PF10412.9 KDO32880.1 - 0.18 10.7 10.1 6 5.7 0.1 4.2 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain ArsA_ATPase PF02374.15 KDO32880.1 - 0.21 10.7 0.4 16 4.6 0.0 2.9 3 0 0 3 3 3 0 Anion-transporting ATPase RHH_5 PF07878.11 KDO32880.1 - 0.3 11.0 2.0 0.59 10.1 0.1 2.6 2 0 0 2 2 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Cytidylate_kin PF02224.18 KDO32880.1 - 2.4 7.8 4.6 17 5.0 0.0 3.4 4 0 0 4 4 3 0 Cytidylate kinase AAA_23 PF13476.6 KDO32880.1 - 3.5 8.1 7.7 4.1 7.9 0.1 3.0 4 0 0 4 4 2 0 AAA domain TPR_2 PF07719.17 KDO32884.1 - 0.00048 20.0 4.3 0.027 14.5 1.5 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO32884.1 - 0.015 15.4 0.2 0.1 12.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_UL36 PF03586.13 KDO32884.1 - 0.038 13.3 0.1 0.62 9.3 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein DUF1018 PF06252.12 KDO32884.1 - 0.21 12.6 1.7 3.4 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) TPR_9 PF13371.6 KDO32884.1 - 0.75 10.0 5.3 0.52 10.5 0.9 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO32884.1 - 1.1 9.2 2.8 5.3 7.0 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO32884.1 - 1.4 9.9 8.5 26 6.0 0.0 5.2 3 1 2 5 5 5 0 Tetratricopeptide repeat FapA PF03961.13 KDO32885.1 - 3.1 6.3 5.8 6.1 5.3 5.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 KDO32885.1 - 9.4 5.5 23.4 10 5.4 13.3 4.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 KDO32887.1 - 0.0041 17.5 1.8 0.0051 17.2 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) Dynactin PF12455.8 KDO32887.1 - 0.0042 16.4 5.4 0.0063 15.8 5.4 1.4 1 1 0 1 1 1 1 Dynein associated protein ApoLp-III PF07464.11 KDO32887.1 - 0.065 13.3 4.7 0.12 12.5 4.6 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.11 KDO32887.1 - 0.068 13.2 2.5 0.091 12.8 1.2 1.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SF-assemblin PF06705.11 KDO32887.1 - 0.1 11.9 3.7 0.47 9.8 0.4 2.2 1 1 2 3 3 3 0 SF-assemblin/beta giardin Tropomyosin PF00261.20 KDO32887.1 - 0.2 11.0 7.7 0.039 13.3 3.6 1.7 1 1 1 2 2 2 0 Tropomyosin Tup_N PF08581.10 KDO32887.1 - 2.3 8.6 6.1 7.2 7.0 0.4 3.4 3 1 1 4 4 4 0 Tup N-terminal YabA PF06156.13 KDO32887.1 - 3.9 8.2 6.9 1.4 9.6 1.0 2.5 3 0 0 3 3 3 0 Initiation control protein YabA Ank_2 PF12796.7 KDO32888.1 - 4.3e-48 161.8 10.1 6.2e-19 68.4 1.1 5.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KDO32888.1 - 1.1e-41 139.4 22.3 1.2e-05 25.6 0.0 9.9 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 KDO32888.1 - 1e-38 131.2 6.8 3.5e-07 30.6 0.0 7.5 5 2 3 8 8 6 6 Ankyrin repeats (many copies) AAA PF00004.29 KDO32888.1 - 4.5e-36 124.2 0.2 1.2e-13 51.7 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 KDO32888.1 - 3.8e-31 106.7 19.0 6e-09 36.0 0.5 7.2 3 1 4 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32888.1 - 1.4e-28 95.8 9.1 0.0017 18.7 0.0 10.4 8 2 2 10 10 9 5 Ankyrin repeat AAA_lid_6 PF17866.1 KDO32888.1 - 1.6e-14 53.8 0.4 0.0014 18.8 0.0 4.0 3 0 0 3 3 3 3 AAA lid domain AAA_5 PF07728.14 KDO32888.1 - 2.1e-11 44.0 0.4 0.0063 16.5 0.0 3.8 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO32888.1 - 3.5e-11 43.5 6.1 0.13 12.5 0.1 6.6 3 3 1 4 4 4 3 AAA domain Mg_chelatase PF01078.21 KDO32888.1 - 1.2e-09 37.9 1.3 0.014 14.8 0.0 5.1 3 2 2 5 5 5 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KDO32888.1 - 2e-09 37.6 0.1 0.012 15.4 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KDO32888.1 - 5.8e-09 36.6 2.8 0.012 16.0 0.0 4.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KDO32888.1 - 1.6e-08 34.8 0.1 0.1 12.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KDO32888.1 - 2.1e-08 34.0 0.2 0.024 14.4 0.0 3.6 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KDO32888.1 - 9.7e-08 32.6 0.0 0.078 13.5 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KDO32888.1 - 1.7e-07 31.2 12.8 0.0058 16.4 0.2 4.1 4 1 0 4 4 3 3 AAA domain Sigma54_activat PF00158.26 KDO32888.1 - 3.6e-07 30.0 3.4 0.086 12.5 0.0 5.7 3 3 1 4 4 4 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KDO32888.1 - 4.7e-07 30.0 0.1 0.11 12.6 0.0 4.1 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_2 PF07724.14 KDO32888.1 - 6.2e-07 29.7 0.0 0.018 15.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) TniB PF05621.11 KDO32888.1 - 1.7e-06 27.6 0.1 0.84 9.0 0.1 4.5 3 2 0 4 4 4 2 Bacterial TniB protein RNA_helicase PF00910.22 KDO32888.1 - 2.7e-06 27.7 0.0 2.1 8.8 0.0 3.7 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.12 KDO32888.1 - 2.8e-06 27.3 0.1 0.012 15.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 KDO32888.1 - 3.7e-06 26.8 0.1 0.44 10.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KDO32888.1 - 1.7e-05 24.5 0.1 0.49 9.9 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region CbiA PF01656.23 KDO32888.1 - 0.00016 21.7 1.2 2.1 8.4 0.0 3.6 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 KDO32888.1 - 0.00023 21.0 1.3 7.9 6.2 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_17 PF13207.6 KDO32888.1 - 0.00059 20.3 0.3 0.56 10.6 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KDO32888.1 - 0.00066 20.0 14.5 0.045 14.0 0.2 5.4 5 2 0 5 5 4 1 AAA domain AAA_3 PF07726.11 KDO32888.1 - 0.00075 19.4 0.2 1 9.2 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KDO32888.1 - 0.00084 18.7 4.1 5.6 6.1 0.0 4.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KDO32888.1 - 0.00095 19.7 0.3 8.5 6.9 0.0 3.8 3 1 0 3 3 3 0 ABC transporter ResIII PF04851.15 KDO32888.1 - 0.0012 18.9 2.5 0.14 12.1 0.0 3.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KDO32888.1 - 0.0013 19.1 9.2 3.1 8.1 0.1 4.7 3 3 2 5 5 4 1 AAA domain AAA_29 PF13555.6 KDO32888.1 - 0.0019 17.9 0.4 18 5.2 0.0 4.1 4 0 0 4 4 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 KDO32888.1 - 0.0021 17.7 1.7 2.6 7.6 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain TsaE PF02367.17 KDO32888.1 - 0.0034 17.4 4.6 0.68 9.9 0.0 3.6 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 KDO32888.1 - 0.0037 17.4 0.0 4.7 7.3 0.0 3.1 3 0 0 3 3 2 0 Torsin PhoH PF02562.16 KDO32888.1 - 0.0074 15.8 2.0 6.2 6.2 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein ATPase PF06745.13 KDO32888.1 - 0.0086 15.5 0.2 2.5 7.4 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_11 PF13086.6 KDO32888.1 - 0.013 15.3 0.0 13 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KDO32888.1 - 0.023 14.5 0.7 4.6 6.9 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 KDO32888.1 - 0.028 14.3 0.6 35 4.2 0.0 3.6 4 0 0 4 4 3 0 NTPase APS_kinase PF01583.20 KDO32888.1 - 0.052 13.5 0.4 12 5.8 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase KTI12 PF08433.10 KDO32888.1 - 0.053 13.0 0.1 7.8 5.8 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 CoaE PF01121.20 KDO32888.1 - 0.06 13.0 1.2 4.6 6.9 0.0 3.6 4 0 0 4 4 3 0 Dephospho-CoA kinase T2SSE PF00437.20 KDO32888.1 - 0.086 11.9 0.0 4.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 KDO32888.1 - 0.087 11.7 6.5 7.9 5.3 0.1 4.1 6 0 0 6 6 4 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KDO32888.1 - 0.096 12.0 0.0 22 4.3 0.0 3.4 4 0 0 4 4 4 0 Zeta toxin SKI PF01202.22 KDO32888.1 - 0.1 12.7 0.1 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase ArsA_ATPase PF02374.15 KDO32888.1 - 0.17 11.0 0.6 15 4.6 0.0 2.9 3 0 0 3 3 3 0 Anion-transporting ATPase DUF3987 PF13148.6 KDO32888.1 - 0.23 10.5 5.6 1.8 7.5 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3987) RHH_5 PF07878.11 KDO32888.1 - 0.9 9.5 5.2 1.7 8.6 0.1 3.0 3 0 0 3 3 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 AAA_23 PF13476.6 KDO32888.1 - 3.7 8.0 8.5 2.3 8.6 0.1 3.0 4 0 0 4 4 2 0 AAA domain Ank_2 PF12796.7 KDO32891.1 - 1.3e-20 73.8 8.1 4.6e-05 23.9 0.1 6.4 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32891.1 - 8.9e-12 45.3 16.7 0.33 11.6 0.5 10.0 7 3 1 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32891.1 - 1.7e-11 44.1 7.2 0.57 10.6 0.0 8.9 6 2 3 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32891.1 - 5e-10 38.8 8.1 4.9 8.1 0.0 11.0 11 1 0 11 11 11 1 Ankyrin repeat Ank PF00023.30 KDO32891.1 - 0.67 10.5 4.1 1.2e+02 3.3 0.0 5.6 4 2 1 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 KDO32892.1 - 2.2e-37 127.5 6.4 7.1e-11 42.5 0.5 6.3 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32892.1 - 2.4e-31 107.7 12.6 8.6e-10 39.0 0.0 7.9 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO32892.1 - 1.6e-30 104.2 16.5 0.00035 20.9 0.1 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 KDO32892.1 - 1e-29 99.2 10.0 0.021 15.3 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KDO32892.1 - 2.2e-26 91.6 10.7 4.6e-06 26.8 0.0 7.7 4 3 5 9 9 9 7 Ankyrin repeats (many copies) FYVE PF01363.21 KDO32892.1 - 2.5e-20 72.4 7.7 4.3e-20 71.6 6.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger BTB PF00651.31 KDO32892.1 - 1.8e-14 53.9 0.0 1.2e-13 51.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain FYVE_2 PF02318.16 KDO32892.1 - 0.0049 17.1 6.5 0.012 15.8 6.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger MOR2-PAG1_mid PF14228.6 KDO32892.1 - 0.036 11.7 0.0 0.077 10.6 0.0 1.4 2 0 0 2 2 2 0 Cell morphogenesis central region ADK_lid PF05191.14 KDO32892.1 - 0.33 11.0 2.5 1.8 8.6 2.5 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid IBR PF01485.21 KDO32892.1 - 0.39 11.0 4.5 1.1 9.6 4.5 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 KDO32892.1 - 6.8 6.8 10.0 8.4 6.5 2.2 3.0 2 1 0 3 3 3 0 Double zinc ribbon Ank_2 PF12796.7 KDO32893.1 - 2e-26 92.3 0.3 2.6e-13 50.3 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32893.1 - 2.2e-22 79.1 0.3 3.5e-06 27.4 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO32893.1 - 2.7e-22 78.2 5.8 0.00037 20.8 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KDO32893.1 - 1.6e-20 72.9 4.5 3.9e-05 23.9 0.0 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO32893.1 - 2.4e-19 67.4 0.9 0.00071 19.8 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat LRR_4 PF12799.7 KDO32894.1 - 0.0053 17.1 2.0 0.52 10.8 1.1 3.4 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO32894.1 - 0.19 11.8 6.6 2.8 8.2 0.1 4.0 3 1 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 KDO32894.1 - 0.38 10.5 4.0 1.4 8.8 1.6 3.0 2 1 1 3 3 3 0 Leucine rich repeat WW PF00397.26 KDO32895.1 - 5.2e-09 36.0 0.2 1e-08 35.1 0.2 1.5 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 KDO32895.1 - 1.9e-05 24.9 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO32895.1 - 0.00055 20.2 0.0 0.0018 18.5 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO32895.1 - 0.001 18.9 0.0 0.0031 17.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Fib_alpha PF08702.10 KDO32895.1 - 0.0014 18.8 2.0 0.0014 18.8 2.0 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Phage_lysis PF03245.13 KDO32895.1 - 0.0057 16.8 0.8 0.015 15.4 0.8 1.7 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein DUF5082 PF16888.5 KDO32895.1 - 0.014 15.7 2.3 0.016 15.5 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KDO32895.1 - 0.042 13.2 1.9 0.061 12.7 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 KDO32895.1 - 0.048 14.0 4.8 0.47 10.8 0.5 2.5 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) MIP-T3_C PF17749.1 KDO32895.1 - 0.2 11.6 5.3 1.1 9.2 2.1 2.8 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region TACC_C PF05010.14 KDO32895.1 - 0.35 10.6 2.6 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ABC_tran_CTD PF16326.5 KDO32895.1 - 0.5 10.7 3.3 13 6.1 0.9 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 KDO32895.1 - 1.1 9.2 5.2 6 6.8 4.5 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 KDO32895.1 - 1.8 8.8 14.2 0.048 13.9 6.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1043 PF06295.12 KDO32895.1 - 1.9 8.5 10.4 5.3 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) V-SNARE PF05008.15 KDO32895.1 - 2.3 8.6 5.5 3 8.3 0.4 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-CCCH_3 PF15663.5 KDO32897.1 - 0.046 13.9 0.1 0.17 12.1 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger containing family Mito_carr PF00153.27 KDO32898.1 - 6.5e-42 141.4 2.6 2.8e-21 75.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAN_4 PF14295.6 KDO32899.1 - 7.4e-18 64.2 28.4 8.8e-07 28.7 5.6 4.0 4 0 0 4 4 4 3 PAN domain PAN_1 PF00024.26 KDO32899.1 - 2.9e-14 52.8 7.5 4.4e-05 23.3 1.4 3.6 2 1 1 3 3 3 3 PAN domain Ricin_B_lectin PF00652.22 KDO32899.1 - 2.8e-10 40.5 0.4 2.8e-10 40.5 0.4 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO32899.1 - 7.2e-05 23.4 0.8 0.00013 22.6 0.6 2.8 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like PAN_2 PF08276.11 KDO32899.1 - 0.0066 16.5 24.8 0.076 13.1 5.8 3.8 3 0 0 3 3 3 2 PAN-like domain PAN_3 PF08277.12 KDO32899.1 - 0.27 11.1 17.4 2.6 7.9 1.7 3.6 3 0 0 3 3 3 0 PAN-like domain LEA_6 PF10714.9 KDO32899.1 - 4.4 7.4 7.4 0.8 9.8 1.0 2.7 1 1 1 2 2 2 0 Late embryogenesis abundant protein 18 PhoPQ_related PF10142.9 KDO32900.1 - 0.0093 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Arginosuc_synth PF00764.19 KDO32901.1 - 3.9e-152 507.1 0.0 4.4e-152 506.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase BON PF04972.17 KDO32901.1 - 0.1 12.9 0.1 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 BON domain QueC PF06508.13 KDO32901.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PBECR5 PF18814.1 KDO32902.1 - 0.23 11.3 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Arginosuc_synth PF00764.19 KDO32903.1 - 5.1e-114 381.6 0.1 1.6e-59 202.2 0.0 2.0 1 1 1 2 2 2 2 Arginosuccinate synthase ThiI PF02568.14 KDO32903.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) BON PF04972.17 KDO32903.1 - 0.038 14.3 0.1 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 BON domain QueC PF06508.13 KDO32903.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PhoPQ_related PF10142.9 KDO32904.1 - 0.023 13.4 0.0 0.043 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BRK PF07533.16 KDO32905.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 BRK domain KH_1 PF00013.29 KDO32907.1 - 1.8e-80 264.8 0.3 4.2e-10 39.3 0.0 11.0 12 0 0 12 12 12 9 KH domain KH_2 PF07650.17 KDO32907.1 - 1.5e-16 59.9 7.5 0.028 14.3 0.2 8.2 8 0 0 8 8 8 5 KH domain KH_4 PF13083.6 KDO32907.1 - 2.7e-15 56.0 5.8 0.022 14.6 0.0 7.8 6 1 1 7 7 7 5 KH domain SLS PF14611.6 KDO32907.1 - 9e-12 45.3 17.9 0.0039 17.0 0.1 7.9 4 2 5 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 KDO32907.1 - 4.5e-07 29.9 7.4 0.67 10.1 0.0 6.5 6 0 0 6 6 6 2 NusA-like KH domain MOEP19 PF16005.5 KDO32907.1 - 0.00017 21.5 0.0 5.3 7.1 0.0 5.6 7 0 0 7 7 7 1 KH-like RNA-binding domain DUF5003 PF16394.5 KDO32907.1 - 0.037 13.2 0.0 0.1 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Mur_ligase_M PF08245.12 KDO32908.1 - 4.8e-09 36.5 0.0 8.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KDO32908.1 - 2.5e-06 27.7 1.1 1.7e-05 25.0 0.0 2.9 3 1 1 4 4 4 1 Mur ligase family, glutamate ligase domain DUF4793 PF16041.5 KDO32908.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) zinc_ribbon_16 PF17034.5 KDO32910.1 - 2.2e-19 69.9 12.1 6.5e-19 68.4 12.1 1.8 1 1 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 KDO32910.1 - 9.3e-05 23.1 3.2 0.08 13.8 0.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KDO32910.1 - 0.0026 17.4 8.7 0.0098 15.5 8.7 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KDO32912.1 - 1e-19 70.9 7.2 9.3e-05 22.9 0.2 5.8 3 1 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO32912.1 - 5.8e-14 52.3 9.5 0.01 16.4 0.0 7.0 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO32912.1 - 1.1e-12 47.9 20.5 0.0031 17.8 0.1 9.4 4 2 7 11 11 11 6 Ankyrin repeats (many copies) DUF5049 PF16468.5 KDO32912.1 - 5.4e-05 23.0 0.7 2.9 7.8 0.0 4.9 4 1 1 5 5 5 2 Domain of unknown function (DUF5049) Ank_3 PF13606.6 KDO32912.1 - 0.00071 19.8 19.6 3 8.7 0.0 10.2 13 0 0 13 13 13 1 Ankyrin repeat Ank PF00023.30 KDO32912.1 - 0.006 17.0 9.9 5.9 7.5 0.0 6.8 5 2 0 5 5 5 1 Ankyrin repeat Beta-lactamase PF00144.24 KDO32913.1 - 1.8e-48 165.5 2.3 2.2e-48 165.2 2.3 1.1 1 0 0 1 1 1 1 Beta-lactamase HIRAN PF08797.11 KDO32913.1 - 0.00036 20.4 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 HIRAN domain FA_desaturase PF00487.24 KDO32914.1 - 6e-31 108.2 15.9 6e-31 108.2 15.9 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KDO32914.1 - 1.3e-23 82.9 0.0 2e-21 75.9 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 KDO32914.1 - 0.0025 17.9 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone DUF4203 PF13886.6 KDO32915.1 - 1.2e-23 83.9 32.2 1.7e-23 83.4 32.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3522 PF12036.8 KDO32915.1 - 0.041 14.2 6.5 0.85 9.9 6.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Lactamase_B_2 PF12706.7 KDO32916.1 - 5.6e-18 65.2 2.2 1.3e-14 54.2 0.2 3.4 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KDO32916.1 - 1.1e-12 47.5 0.0 2.8e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KDO32916.1 - 0.00057 19.9 0.2 0.0013 18.8 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Hydrolase_3 PF08282.12 KDO32917.1 - 7.4e-46 157.0 0.0 8.4e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KDO32917.1 - 9.3e-08 31.9 0.0 6.4e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KDO32917.1 - 7.4e-06 26.4 0.0 0.15 12.3 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KDO32917.1 - 0.00019 21.9 1.9 1.5 9.2 0.0 3.2 1 1 2 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KDO32917.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SWIRM PF04433.17 KDO32918.1 - 5e-28 97.3 0.0 1.2e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KDO32918.1 - 1.8e-15 56.7 8.8 4.5e-15 55.4 8.8 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM-assoc_2 PF16496.5 KDO32918.1 - 0.00083 18.3 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Glyco_hydro_15 PF00723.21 KDO32918.1 - 0.11 11.3 0.5 0.16 10.7 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 WD40 PF00400.32 KDO32919.1 - 0.16 12.9 0.0 1.4 9.9 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat LRR_4 PF12799.7 KDO32920.1 - 8.9e-10 38.7 12.3 0.0058 17.0 0.4 5.1 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO32920.1 - 6.2e-08 32.3 3.1 8e-05 22.2 0.8 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KDO32920.1 - 8.4e-08 31.9 10.2 9e-05 22.2 2.4 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KDO32920.1 - 0.12 12.5 13.6 0.6 10.3 0.5 5.4 6 1 1 7 7 7 0 Leucine Rich repeat SHE3 PF17078.5 KDO32921.1 - 0.011 15.4 5.7 0.029 14.1 5.7 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 KDO32921.1 - 0.12 12.6 2.1 0.88 9.9 0.5 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KDO32921.1 - 0.23 11.9 2.8 8.1 6.9 0.0 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4558 PF15104.6 KDO32921.1 - 0.84 9.7 8.1 0.24 11.5 3.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) HEAT PF02985.22 KDO32921.1 - 1.1 9.7 3.9 78 3.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Tup_N PF08581.10 KDO32921.1 - 1.7 9.0 10.2 5.6 7.3 1.5 3.7 2 1 1 3 3 3 0 Tup N-terminal Viral_P18 PF04521.13 KDO32921.1 - 2.8 7.8 5.9 17 5.2 0.3 2.9 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein PhaP_Bmeg PF09602.10 KDO32921.1 - 3.5 7.5 6.6 7.7 6.4 0.6 2.5 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Flg_hook PF02120.16 KDO32921.1 - 3.9 7.4 7.7 19 5.2 1.5 3.0 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK Spc7 PF08317.11 KDO32921.1 - 7.1 5.4 25.9 1.1 8.1 0.7 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 KDO32921.1 - 9 6.8 6.4 5.1 7.6 1.7 2.9 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins RrnaAD PF00398.20 KDO32922.1 - 2.6e-55 187.4 0.0 3.5e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KDO32922.1 - 2e-06 28.4 0.1 7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO32922.1 - 0.00058 20.5 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TctC PF03401.14 KDO32922.1 - 0.0016 17.6 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor PCMT PF01135.19 KDO32922.1 - 0.0063 16.3 0.0 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KDO32922.1 - 0.038 13.8 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KDO32922.1 - 0.045 14.5 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain VASt PF16016.5 KDO32925.1 - 3.5e-24 86.0 0.2 5.7e-24 85.3 0.2 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain FYVE PF01363.21 KDO32925.1 - 3.1e-09 36.9 15.0 5.3e-09 36.1 15.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger GRAM PF02893.20 KDO32925.1 - 1.2e-06 28.4 0.1 2.9e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 GRAM domain FYVE_2 PF02318.16 KDO32925.1 - 0.36 11.1 9.3 0.82 9.9 9.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4460 PF14687.6 KDO32926.1 - 9.1e-19 67.5 0.0 2.3e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) zf-AN1 PF01428.16 KDO32927.1 - 9.2e-10 38.5 8.1 1.4e-09 38.0 8.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4203 PF13886.6 KDO32930.1 - 5.3e-22 78.5 36.8 9.5e-22 77.6 36.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4173 PF13777.6 KDO32931.1 - 0.071 12.5 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Amidohydro_2 PF04909.14 KDO32932.1 - 1.6e-20 74.1 3.6 2.3e-20 73.6 3.6 1.3 1 0 0 1 1 1 1 Amidohydrolase GAF PF01590.26 KDO32932.1 - 0.03 14.9 0.0 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 GAF domain Peptidase_S8 PF00082.22 KDO32934.1 - 3e-35 121.9 5.0 3e-35 121.9 5.0 2.1 2 0 0 2 2 2 1 Subtilase family SchA_CurD PF04486.12 KDO32934.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 SchA/CurD like domain HECT PF00632.25 KDO32935.1 - 3.2e-65 220.6 0.0 9.8e-65 219.0 0.0 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO32935.1 - 0.00023 20.4 3.0 0.00041 19.6 3.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FdhE PF04216.12 KDO32935.1 - 0.15 11.9 3.2 0.28 11.0 3.2 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Vps36-NZF-N PF16988.5 KDO32935.1 - 0.3 10.5 3.8 1.3 8.5 3.8 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PIP5K PF01504.18 KDO32936.1 - 1.3e-53 182.0 0.0 1.7e-51 175.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 KDO32936.1 - 4.7e-08 32.6 9.6 8.3e-08 31.8 9.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KDO32936.1 - 4.3e-06 26.1 7.6 6.3e-06 25.5 6.7 1.6 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KDO32936.1 - 0.00043 19.7 9.7 0.00099 18.5 9.7 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KDO32936.1 - 0.0099 15.3 6.4 0.016 14.6 6.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tcp10_C PF07202.13 KDO32938.1 - 3.6e-23 82.4 2.8 1.1e-22 80.9 2.8 1.7 1 1 0 1 1 1 1 T-complex protein 10 C-terminus APG6_N PF17675.1 KDO32938.1 - 0.13 12.8 16.8 0.048 14.2 4.2 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 KDO32938.1 - 0.18 11.2 8.3 0.27 10.5 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 KDO32938.1 - 0.35 10.4 10.9 0.051 13.1 3.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_TATA_bd PF12325.8 KDO32938.1 - 1.2 9.4 21.3 0.57 10.4 13.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 KDO32938.1 - 3.8 7.9 8.1 5.9 7.3 0.4 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Borrelia_P83 PF05262.11 KDO32938.1 - 4.9 5.5 14.8 7.3 5.0 14.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RNR_N PF08343.10 KDO32938.1 - 5.1 7.2 6.3 17 5.5 1.4 2.5 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Ribosomal_S4e PF00900.20 KDO32939.1 - 4.4e-31 106.6 3.4 8.2e-31 105.7 0.8 2.5 3 0 0 3 3 3 1 Ribosomal family S4e 40S_S4_C PF16121.5 KDO32939.1 - 4.9e-22 77.3 0.0 9e-22 76.5 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KDO32939.1 - 2e-18 66.2 9.0 2e-18 66.2 9.0 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KDO32939.1 - 3e-07 30.1 0.0 5.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KDO32939.1 - 0.00046 20.0 0.1 0.00046 20.0 0.1 3.3 5 0 0 5 5 5 1 KOW motif Sipho_tail PF05709.11 KDO32939.1 - 0.093 12.1 0.3 0.2 11.1 0.2 1.5 1 1 0 1 1 1 0 Phage tail protein Pro_isomerase PF00160.21 KDO32940.1 - 1.3e-25 90.5 0.0 1.5e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_19 PF14559.6 KDO32941.1 - 0.065 13.8 0.2 0.098 13.2 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TMEM117 PF15113.6 KDO32942.1 - 1.8e-29 103.0 2.8 8.8e-22 77.6 0.3 2.4 2 0 0 2 2 2 2 TMEM117 protein family Ion_trans_2 PF07885.16 KDO32942.1 - 7e-07 29.1 8.2 7e-07 29.1 8.2 3.7 4 0 0 4 4 4 1 Ion channel SK_channel PF03530.14 KDO32942.1 - 0.0031 17.5 0.3 0.013 15.5 0.3 2.1 1 0 0 1 1 1 1 Calcium-activated SK potassium channel DUF4497 PF14924.6 KDO32943.1 - 2.8e-13 50.3 0.0 6.4e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4497) DUF3948 PF13134.6 KDO32943.1 - 0.052 13.2 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Thioredoxin PF00085.20 KDO32944.1 - 9.9e-64 211.8 0.0 2.1e-32 111.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KDO32944.1 - 1.1e-16 61.5 0.1 2.1e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KDO32944.1 - 1.3e-14 54.3 0.0 1.6e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KDO32944.1 - 1e-12 48.4 0.2 5.6e-05 23.6 0.2 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO32944.1 - 1e-09 38.5 0.1 0.0013 18.9 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO32944.1 - 1.2e-07 32.0 0.0 0.024 15.0 0.0 3.5 2 2 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KDO32944.1 - 5.5e-05 22.9 0.1 0.34 10.6 0.0 2.4 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KDO32944.1 - 0.00017 21.5 0.1 0.15 11.9 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family TraF PF13728.6 KDO32944.1 - 0.00027 20.8 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KDO32944.1 - 0.0046 16.7 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.11 KDO32944.1 - 0.0096 15.9 0.1 0.51 10.3 0.0 2.7 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 KDO32944.1 - 0.025 14.7 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DctP PF03480.13 KDO32944.1 - 0.04 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Acetone_carb_G PF08882.11 KDO32944.1 - 0.098 12.8 0.0 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit PHD_Oberon PF07227.11 KDO32944.1 - 0.14 12.0 0.0 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein HECT PF00632.25 KDO32945.1 - 2.4e-75 253.9 0.0 3.4e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO32945.1 - 0.0056 16.0 1.7 0.011 15.1 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF4064 PF13273.6 KDO32947.1 - 1.4 9.2 4.6 1.1 9.5 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_U4 PF03419.13 KDO32947.1 - 5.5 6.2 8.4 0.4 9.9 3.0 1.7 2 0 0 2 2 2 0 Sporulation factor SpoIIGA HECT PF00632.25 KDO32948.1 - 1e-72 245.2 0.0 1.4e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps36-NZF-N PF16988.5 KDO32948.1 - 0.33 10.4 3.1 2.3 7.7 3.1 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Med14 PF08638.11 KDO32949.1 - 4.5e-40 137.1 0.0 7.8e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 HECT PF00632.25 KDO32950.1 - 9.1e-68 229.0 0.0 1.2e-67 228.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CBM9_1 PF06452.11 KDO32951.1 - 9.3e-12 45.2 0.1 1.4e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 KDO32951.1 - 3e-06 27.1 0.0 4.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding family 9 DUF2689 PF10894.8 KDO32951.1 - 0.15 11.9 0.2 12 5.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2689) Baculo_PEP_C PF04513.12 KDO32952.1 - 0.015 15.4 1.2 0.033 14.2 1.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PAN_4 PF14295.6 KDO32953.1 - 2.9e-32 110.3 48.0 2.9e-07 30.3 1.2 5.7 5 0 0 5 5 5 5 PAN domain PAN_1 PF00024.26 KDO32953.1 - 4.9e-13 48.9 27.5 0.015 15.2 0.2 5.3 4 1 1 5 5 5 5 PAN domain DUF1397 PF07165.11 KDO32953.1 - 0.00053 19.5 4.7 0.2 11.1 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1397) MAR_sialic_bdg PF10564.9 KDO32953.1 - 3.6 7.7 33.8 6.2 6.9 1.1 5.3 5 0 0 5 5 5 0 Sialic-acid binding micronemal adhesive repeat PTCB-BRCT PF12738.7 KDO32954.1 - 2.9e-44 148.8 1.0 1.1e-15 57.3 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KDO32954.1 - 5.7e-31 106.7 0.0 2.4e-09 37.4 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KDO32954.1 - 4.2e-13 49.5 0.0 0.02 15.3 0.0 5.2 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KDO32954.1 - 3.3e-09 36.7 0.2 0.069 13.2 0.0 5.3 5 1 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KDO32954.1 - 1.1e-08 35.3 0.0 0.087 13.1 0.0 5.2 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KDO32954.1 - 0.00091 19.1 0.0 2.3 8.1 0.0 3.4 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain DapB_N PF01113.20 KDO32954.1 - 0.2 11.8 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus zf-RING_2 PF13639.6 KDO32955.1 - 1.4e-10 41.4 35.2 3.1e-10 40.2 5.7 4.9 4 1 1 5 5 5 1 Ring finger domain FYVE PF01363.21 KDO32955.1 - 6.9e-10 38.9 13.9 6.9e-10 38.9 13.9 3.5 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_11 PF17123.5 KDO32955.1 - 2.4e-09 36.8 3.5 2.4e-09 36.8 3.5 3.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 KDO32955.1 - 9.4e-08 31.9 4.8 9.4e-08 31.9 4.8 4.2 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO32955.1 - 2.2e-07 30.8 0.4 2.2e-07 30.8 0.4 3.9 3 1 1 4 4 4 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO32955.1 - 6.8e-07 29.0 4.7 6.8e-07 29.0 4.7 4.8 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO32955.1 - 2e-06 27.6 6.0 2e-06 27.6 6.0 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KDO32955.1 - 0.00093 18.9 2.1 0.00093 18.9 2.1 4.4 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain PHD PF00628.29 KDO32955.1 - 0.0041 17.0 4.9 0.0041 17.0 4.9 4.4 4 1 1 5 5 5 1 PHD-finger zf-ANAPC11 PF12861.7 KDO32955.1 - 0.0052 16.8 1.1 0.0052 16.8 1.1 3.1 3 1 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KDO32955.1 - 0.0076 16.4 5.7 0.0076 16.4 5.7 4.7 5 1 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KDO32955.1 - 0.01 16.1 7.3 0.01 16.1 7.3 4.4 4 1 1 5 5 5 0 RING-H2 zinc finger domain Zn-ribbon_8 PF09723.10 KDO32955.1 - 0.015 15.4 22.8 0.094 12.9 1.2 5.0 4 1 0 4 4 4 0 Zinc ribbon domain eIF3_subunit PF08597.10 KDO32955.1 - 0.04 13.8 0.6 0.066 13.1 0.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Opy2 PF09463.10 KDO32955.1 - 5.6 7.4 20.9 2.4 8.5 2.3 4.3 4 0 0 4 4 4 0 Opy2 protein zf-C4_Topoisom PF01396.19 KDO32955.1 - 7.1 6.5 11.8 2.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Prok-RING_4 PF14447.6 KDO32955.1 - 10 6.1 33.3 0.31 10.9 5.1 4.4 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 BLOC1_2 PF10046.9 KDO32956.1 - 0.002 18.4 9.6 0.0023 18.2 5.5 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TipAS PF07739.13 KDO32956.1 - 0.0043 17.6 5.2 0.041 14.4 3.3 2.2 1 1 1 2 2 2 1 TipAS antibiotic-recognition domain AAT PF03417.16 KDO32956.1 - 0.0091 15.7 2.1 0.011 15.4 2.1 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF948 PF06103.11 KDO32956.1 - 0.02 15.1 1.4 0.02 15.1 1.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_1_1 PF08200.11 KDO32956.1 - 0.036 14.5 1.7 4.9 7.6 0.5 2.5 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein Spore_III_AB PF09548.10 KDO32956.1 - 0.056 13.6 2.0 0.071 13.2 2.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF1041 PF06292.17 KDO32956.1 - 0.078 13.4 5.4 0.12 12.8 5.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) DUF737 PF05300.11 KDO32956.1 - 0.57 10.5 9.9 2.8 8.2 9.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF737) DUF3015 PF11220.8 KDO32956.1 - 2.2 8.1 5.1 1.1 9.1 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3015) HR1 PF02185.16 KDO32956.1 - 3.2 7.9 9.1 1.8 8.7 5.9 2.2 1 1 1 2 2 2 0 Hr1 repeat vATP-synt_E PF01991.18 KDO32957.1 - 0.1 12.0 1.3 0.11 11.9 1.2 1.2 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RSRP PF17069.5 KDO32958.1 - 0.43 10.1 6.7 0.47 10.0 6.7 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 GAF PF01590.26 KDO32959.1 - 1e-23 84.4 0.1 4.4e-13 50.0 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 KDO32959.1 - 2.3e-10 40.9 0.2 5.1e-05 23.6 0.0 5.5 5 2 0 5 5 5 3 GAF domain SpoVT_C PF15714.5 KDO32959.1 - 0.16 12.0 0.1 1 9.4 0.0 2.2 2 1 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Cytochrom_B561 PF03188.16 KDO32960.1 - 2.4e-17 63.4 1.6 2.4e-17 63.4 1.6 2.2 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2818 PF10993.8 KDO32960.1 - 0.03 14.9 0.4 0.054 14.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2818) DUF4079 PF13301.6 KDO32960.1 - 3.6 7.7 8.4 1.3 9.2 3.6 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) MIT PF04212.18 KDO32961.1 - 0.011 15.7 1.8 1.4 9.0 0.1 2.7 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2378 PF09536.10 KDO32961.1 - 0.028 14.3 0.0 0.091 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) TOM20_plant PF06552.12 KDO32961.1 - 0.083 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 PUF PF00806.19 KDO32961.1 - 0.13 12.1 0.1 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat EF-hand_1 PF00036.32 KDO32962.1 - 1.1e-19 68.4 0.1 1.9e-06 27.0 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO32962.1 - 8.6e-19 65.8 0.1 0.0011 18.7 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO32962.1 - 3.5e-17 61.1 0.3 0.0073 15.8 0.0 4.6 3 1 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO32962.1 - 1.6e-16 60.5 0.0 6e-07 29.8 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO32962.1 - 4.8e-13 48.7 0.0 1.8e-05 24.4 0.0 4.1 2 1 1 3 3 3 3 EF-hand domain pair LRR_6 PF13516.6 KDO32962.1 - 4.2e-12 45.1 17.1 0.023 14.8 0.0 7.2 7 0 0 7 7 6 4 Leucine Rich repeat DUF4476 PF14771.6 KDO32962.1 - 1.1e-09 38.4 0.3 1.7e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4476) EF-hand_9 PF14658.6 KDO32962.1 - 3e-08 33.9 0.1 0.0025 18.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain LRR_8 PF13855.6 KDO32962.1 - 0.03 14.1 12.0 0.22 11.3 0.7 5.1 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KDO32962.1 - 0.074 13.6 7.7 8.6 7.3 0.2 5.1 4 1 1 5 5 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO32962.1 - 0.077 13.5 12.2 5.4 7.6 1.7 4.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) zf-CHCC PF10276.9 KDO32963.1 - 6.8e-16 58.0 0.8 9.2e-16 57.6 0.8 1.2 1 0 0 1 1 1 1 Zinc-finger domain GATA PF00320.27 KDO32963.1 - 0.032 13.9 0.3 0.049 13.3 0.3 1.3 1 0 0 1 1 1 0 GATA zinc finger PhyH PF05721.13 KDO32964.1 - 2.3e-07 31.3 0.4 4.4e-07 30.4 0.4 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zip PF02535.22 KDO32965.1 - 6.4e-45 153.8 21.2 9e-35 120.5 10.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF2070 PF09843.9 KDO32965.1 - 0.19 10.0 5.4 0.29 9.4 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_3 PF12698.7 KDO32965.1 - 6.7 5.7 13.7 0.19 10.8 6.8 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Claudin_2 PF13903.6 KDO32965.1 - 8.5 6.1 12.1 0.88 9.3 2.1 2.8 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF1218 PF06749.12 KDO32965.1 - 8.6 7.0 13.2 9.2 6.9 1.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) RRM_1 PF00076.22 KDO32966.1 - 4.9e-33 112.8 0.0 8.4e-16 57.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO32966.1 - 2.7e-05 24.2 0.0 0.4 10.8 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO32966.1 - 0.035 14.1 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KDO32966.1 - 0.047 13.9 1.5 1.6 8.9 0.0 3.2 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter dTDP_sugar_isom PF00908.17 KDO32966.1 - 0.056 13.1 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase ubiquitin PF00240.23 KDO32968.1 - 1.7e-19 69.3 0.0 4.7e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KDO32968.1 - 1.8e-07 30.9 0.0 4.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KDO32968.1 - 0.00017 22.0 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KDO32968.1 - 0.00042 20.8 0.3 0.0044 17.6 0.1 2.5 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain Tudor-knot PF11717.8 KDO32968.1 - 0.00057 19.7 1.1 0.0011 18.8 1.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ubiquitin_4 PF18036.1 KDO32968.1 - 0.017 15.1 0.1 1.4 9.0 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Aminotran_4 PF01063.19 KDO32969.1 - 1.1e-17 64.6 0.0 3.1e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV LRR_6 PF13516.6 KDO32970.1 - 2.2e-15 55.3 8.1 0.0011 18.8 0.1 4.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KDO32970.1 - 2e-06 28.0 0.1 0.058 13.8 0.1 3.7 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO32970.1 - 0.0088 15.8 0.3 2.5 7.9 0.4 3.8 2 1 1 3 3 3 2 Leucine rich repeat Peptidase_S15 PF02129.18 KDO32971.1 - 2.9e-36 125.5 0.0 4.4e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KDO32971.1 - 4e-16 59.6 0.0 6.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KDO32971.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FYVE PF01363.21 KDO32972.1 - 8e-15 54.7 11.4 1.7e-14 53.7 11.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 KDO32972.1 - 1.4e-07 31.9 0.0 3.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain Peptidase_M17 PF00883.21 KDO32973.1 - 2.4e-75 253.7 3.4 3.5e-75 253.2 3.4 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KDO32973.1 - 4.1e-31 107.8 2.0 8.6e-31 106.7 2.0 1.5 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 Carbam_trans_C PF16861.5 KDO32974.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus LRR_6 PF13516.6 KDO32974.1 - 0.58 10.4 6.5 12 6.2 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat Peptidase_M17 PF00883.21 KDO32975.1 - 2.6e-96 322.6 0.2 3.3e-96 322.2 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KDO32975.1 - 1.3e-19 70.6 0.0 3.7e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 GCK PF07802.11 KDO32976.1 - 3.9e-20 72.0 0.7 9.2e-20 70.8 0.7 1.6 1 0 0 1 1 1 1 GCK domain tRNA_lig_CPD PF08302.11 KDO32976.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain SUN PF03856.13 KDO32977.1 - 6.7e-15 55.2 0.6 1.3e-14 54.2 0.6 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF1304 PF06993.12 KDO32977.1 - 0.11 12.5 0.8 0.34 10.9 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Ufd2P_core PF10408.9 KDO32979.1 - 1.6e-47 162.5 0.0 4.3e-29 101.6 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin elongating factor core U-box PF04564.15 KDO32979.1 - 1.2e-23 83.0 0.2 3.1e-23 81.7 0.2 1.8 1 0 0 1 1 1 1 U-box domain ZZ PF00569.17 KDO32979.1 - 7.6e-10 38.5 8.7 7.6e-10 38.5 8.7 3.5 3 0 0 3 3 3 1 Zinc finger, ZZ type C1_2 PF03107.16 KDO32979.1 - 9.2e-06 25.9 24.2 0.021 15.1 0.1 3.7 3 0 0 3 3 3 3 C1 domain Siva PF05458.12 KDO32979.1 - 0.2 11.3 14.4 0.06 13.0 1.4 3.5 3 0 0 3 3 3 0 Cd27 binding protein (Siva) MCM_OB PF17207.3 KDO32979.1 - 0.56 10.0 3.1 0.46 10.4 0.1 2.4 2 0 0 2 2 2 0 MCM OB domain zf-C3HC PF07967.13 KDO32979.1 - 3.5 7.7 8.3 0.27 11.3 1.7 2.6 2 0 0 2 2 2 0 C3HC zinc finger-like FYVE PF01363.21 KDO32979.1 - 8.8 6.5 16.2 0.057 13.6 0.7 3.0 3 0 0 3 3 3 0 FYVE zinc finger Spidroin_N PF16763.5 KDO32980.1 - 0.099 12.7 12.9 0.23 11.5 1.5 2.8 2 1 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Prominin PF05478.11 KDO32980.1 - 0.59 8.0 9.5 0.053 11.5 0.9 2.1 2 0 0 2 2 2 0 Prominin DMPK_coil PF08826.10 KDO32980.1 - 0.86 9.8 16.6 0.2 11.8 4.8 4.0 4 0 0 4 4 4 0 DMPK coiled coil domain like DUF1993 PF09351.10 KDO32980.1 - 2.4 8.3 12.4 0.069 13.3 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Rootletin PF15035.6 KDO32980.1 - 4.6 7.2 24.2 6.1 6.8 18.6 3.2 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 KDO32980.1 - 7.6 6.5 15.5 0.73 9.7 4.2 3.8 2 2 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 KDO32980.1 - 8.9 6.4 11.1 3.4 7.7 4.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) KR PF08659.10 KDO32981.1 - 0.072 13.0 0.7 0.16 11.9 0.7 1.5 1 0 0 1 1 1 0 KR domain Pkinase PF00069.25 KDO32982.1 - 4.9e-19 68.7 0.0 9.1e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SET PF00856.28 KDO32982.1 - 1.4e-16 61.3 0.1 2.3e-15 57.4 0.1 2.5 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KDO32982.1 - 8.4e-11 41.7 7.8 2.4e-10 40.2 7.8 1.9 1 0 0 1 1 1 1 AWS domain Cyclin_N PF00134.23 KDO32982.1 - 2.1e-07 30.8 0.1 4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase_Tyr PF07714.17 KDO32982.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 KDO32982.1 - 0.039 13.3 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like TPR_12 PF13424.6 KDO32983.1 - 1.3e-09 38.2 32.7 0.00017 21.8 0.4 8.2 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO32983.1 - 4.6e-09 35.7 35.8 0.0041 17.1 0.2 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KDO32983.1 - 5.8e-08 32.2 19.8 0.00051 19.9 0.1 6.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO32983.1 - 7e-08 32.0 31.9 0.011 15.5 0.2 10.0 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 KDO32983.1 - 2e-05 24.3 14.2 5e-05 23.0 0.0 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KDO32983.1 - 8.8e-05 22.4 19.6 0.0004 20.4 0.1 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO32983.1 - 0.00019 21.6 30.0 0.14 12.4 0.2 7.4 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KDO32983.1 - 0.00033 21.2 38.5 0.01 16.5 2.5 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO32983.1 - 0.0022 18.7 25.4 2.1 9.4 0.5 8.4 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO32983.1 - 0.0077 16.7 0.2 0.0077 16.7 0.2 8.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TilS PF09179.11 KDO32983.1 - 0.1 13.1 1.7 23 5.6 0.2 3.2 2 0 0 2 2 2 0 TilS substrate binding domain TPR_4 PF07721.14 KDO32983.1 - 0.21 12.3 18.9 0.36 11.6 1.4 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO32983.1 - 1.6 9.5 26.0 2.8 8.8 1.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat NTF2 PF02136.20 KDO32984.1 - 3e-22 79.4 0.0 5.8e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KDO32984.1 - 8.9e-12 44.7 0.1 1.4e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KDO32984.1 - 0.052 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KDO32984.1 - 0.053 13.1 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 KDO32984.1 - 0.058 12.6 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Sec20 PF03908.13 KDO32985.1 - 9.2e-10 38.3 0.2 3.4e-09 36.5 0.2 2.0 1 0 0 1 1 1 1 Sec20 Herpes_UL51 PF04540.13 KDO32985.1 - 0.022 14.5 0.7 0.77 9.5 0.0 2.6 2 0 0 2 2 2 0 Herpesvirus UL51 protein Methyltransf_25 PF13649.6 KDO32986.1 - 0.0032 18.1 0.1 0.015 16.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Raf1_N PF18578.1 KDO32987.1 - 0.039 14.4 0.4 0.052 14.0 0.4 1.2 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain EF-hand_7 PF13499.6 KDO32990.1 - 7.6e-08 32.7 0.2 0.00012 22.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO32990.1 - 5.2e-07 28.8 0.7 0.013 15.0 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KDO32990.1 - 8.4e-07 28.4 4.4 0.047 13.6 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain PLDc PF00614.22 KDO32991.1 - 6.5e-18 64.1 1.8 8.8e-09 35.2 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KDO32991.1 - 1.5e-16 60.5 0.0 6.2e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain ELFV_dehydrog PF00208.21 KDO32992.1 - 4.1e-56 190.4 0.1 6.6e-56 189.7 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KDO32992.1 - 2.1e-24 85.3 0.1 1.6e-15 55.8 0.1 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KDO32992.1 - 0.047 13.6 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain LRR_6 PF13516.6 KDO32993.1 - 1.6e-20 71.3 23.7 0.002 18.0 0.4 8.5 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 KDO32993.1 - 2.6e-05 24.5 9.8 3.5 8.2 1.4 5.0 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO32993.1 - 0.0062 16.9 2.3 5.2 8.0 0.1 5.5 7 0 0 7 7 7 1 Leucine Rich Repeat DUF4476 PF14771.6 KDO32993.1 - 0.044 14.1 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) LRR_8 PF13855.6 KDO32993.1 - 0.81 9.5 21.1 3.6 7.4 2.6 5.7 2 2 3 5 5 5 0 Leucine rich repeat MRP-L47 PF06984.13 KDO32994.1 - 7.4e-25 86.9 0.1 1.2e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KDO32994.1 - 8e-10 38.6 0.5 1.1e-09 38.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L29 protein MscS_TM PF12794.7 KDO32995.1 - 0.12 11.2 0.9 0.21 10.4 0.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 UVR PF02151.19 KDO32996.1 - 1.5e-09 37.2 38.1 0.004 16.8 1.9 5.7 5 0 0 5 5 5 4 UvrB/uvrC motif Nucleoporin_FG PF13634.6 KDO32996.1 - 4.9e-06 27.3 20.7 0.00036 21.3 0.5 4.2 3 1 0 3 3 3 2 Nucleoporin FG repeat region DUF4172 PF13776.6 KDO32996.1 - 0.49 10.8 1.9 1.9 8.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) XhlA PF10779.9 KDO32996.1 - 10 6.4 28.4 1.4 9.2 1.5 5.6 4 1 1 5 5 5 0 Haemolysin XhlA MitMem_reg PF13012.6 KDO32997.1 - 9.6e-21 74.3 0.1 1.8e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KDO32997.1 - 1.3e-19 70.3 0.1 2.7e-19 69.3 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ABC_tran_CTD PF16326.5 KDO32997.1 - 0.043 14.1 0.1 0.071 13.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain AA_permease_2 PF13520.6 KDO33000.1 - 7.2e-29 100.9 30.2 8.8e-29 100.6 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO33000.1 - 1.4e-14 53.6 27.2 3e-14 52.5 27.2 1.5 1 1 0 1 1 1 1 Amino acid permease Methyltransf_25 PF13649.6 KDO33001.1 - 1.2e-13 51.6 0.2 1.1e-09 38.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KDO33001.1 - 4.4e-11 43.3 0.1 9.3e-09 35.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33001.1 - 3.9e-08 33.2 0.0 7.1e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33001.1 - 9.5e-06 26.3 0.0 0.025 15.3 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KDO33001.1 - 0.00019 21.0 0.1 0.68 9.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 KDO33001.1 - 0.0016 18.2 0.0 0.012 15.4 0.0 2.2 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KDO33001.1 - 0.0031 17.1 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 KDO33001.1 - 0.0091 15.8 0.0 0.7 9.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 KDO33001.1 - 0.018 14.5 0.0 0.058 12.8 0.0 1.9 1 0 0 1 1 1 0 Spermine/spermidine synthase domain TPMT PF05724.11 KDO33001.1 - 0.022 14.4 0.2 0.074 12.7 0.1 2.0 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 KDO33001.1 - 0.056 12.7 0.2 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain DUF4159 PF13709.6 KDO33001.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) RabGAP-TBC PF00566.18 KDO33002.1 - 2.7e-51 174.3 0.4 3.6e-51 173.9 0.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SGL PF08450.12 KDO33003.1 - 2.4e-15 56.8 0.0 3.7e-14 52.9 0.0 2.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KDO33003.1 - 0.00037 20.6 0.0 0.093 12.9 0.0 3.5 4 0 0 4 4 4 1 Arylesterase NHL PF01436.21 KDO33003.1 - 0.025 14.6 3.8 57 4.0 0.1 5.8 7 0 0 7 7 7 0 NHL repeat PQQ_3 PF13570.6 KDO33003.1 - 0.23 12.0 5.3 0.29 11.7 0.7 3.2 4 0 0 4 4 4 0 PQQ-like domain Stm1_N PF09598.10 KDO33004.1 - 1.3 9.9 6.4 2.7 8.9 6.4 1.6 1 1 0 1 1 1 0 Stm1 PP2C PF00481.21 KDO33005.1 - 1.3e-66 224.9 0.0 1.7e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 KDO33005.1 - 3.1e-15 56.3 0.1 8.4e-13 48.5 0.0 3.0 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 KDO33005.1 - 5.3e-06 26.7 0.0 1.7e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PP2C_2 PF13672.6 KDO33005.1 - 4.8e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO33005.1 - 0.017 15.0 0.9 0.51 10.2 0.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Methyltr_RsmB-F PF01189.17 KDO33006.1 - 1.2e-28 100.2 0.0 5.4e-16 58.8 0.0 2.4 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KDO33006.1 - 6.7e-07 29.2 0.0 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33006.1 - 4.8e-06 27.2 0.1 3e-05 24.6 0.0 2.3 2 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 KDO33006.1 - 0.00084 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KDO33006.1 - 0.001 19.2 0.0 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KDO33006.1 - 0.0054 16.6 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO33006.1 - 0.007 15.7 0.0 0.033 13.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KDO33006.1 - 0.0098 16.5 0.0 0.22 12.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33006.1 - 0.077 13.8 0.0 0.92 10.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmF_N PF17125.5 KDO33006.1 - 0.089 13.3 0.3 0.5 10.9 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Vir_act_alpha_C PF10400.9 KDO33007.1 - 0.076 13.7 0.4 0.076 13.7 0.4 2.5 3 0 0 3 3 3 0 Virulence activator alpha C-term AAA PF00004.29 KDO33009.1 - 1.7e-38 132.1 0.0 4e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO33009.1 - 1.4e-09 37.6 0.0 6.9e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KDO33009.1 - 6.8e-09 35.9 0.4 9.1e-05 22.5 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO33009.1 - 1.2e-06 28.8 0.0 2.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KDO33009.1 - 4.4e-05 23.3 0.0 9.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KDO33009.1 - 6.2e-05 22.9 0.0 0.00021 21.2 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KDO33009.1 - 0.00023 20.9 0.0 0.012 15.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KDO33009.1 - 0.00064 20.1 0.2 0.0065 16.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO33009.1 - 0.0012 19.1 0.1 0.033 14.5 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO33009.1 - 0.0018 18.5 0.1 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KDO33009.1 - 0.0051 16.9 0.0 0.016 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KDO33009.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KDO33009.1 - 0.01 15.4 0.1 0.025 14.1 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KDO33009.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KDO33009.1 - 0.024 14.4 2.0 0.56 9.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO33009.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.23 KDO33009.1 - 0.031 13.4 0.0 0.2 10.7 0.0 2.2 3 0 0 3 3 3 0 MCM P-loop domain Parvo_NS1 PF01057.17 KDO33009.1 - 0.035 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KDO33009.1 - 0.036 14.6 0.1 0.092 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO33009.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KDO33009.1 - 0.071 13.0 0.2 0.39 10.6 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KDO33009.1 - 0.075 13.3 0.7 0.19 12.0 0.1 2.1 2 1 0 2 2 1 0 AAA domain TsaE PF02367.17 KDO33009.1 - 0.089 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KDO33009.1 - 0.091 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KDO33009.1 - 0.12 12.2 0.0 0.55 10.0 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 KDO33009.1 - 0.22 10.9 0.3 1 8.7 0.0 2.2 2 1 1 3 3 3 0 KaiC GBP PF02263.19 KDO33010.1 - 2.7e-08 33.4 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain DUF1765 PF08578.10 KDO33011.1 - 3.8e-06 27.4 1.4 1e-05 26.0 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) APOBEC2 PF18772.1 KDO33011.1 - 0.014 15.5 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 APOBEC_C PF05240.14 KDO33011.1 - 0.052 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 APOBEC-like C-terminal domain DUF1084 PF06454.11 KDO33012.1 - 4.8e-07 29.4 5.0 9.7e-07 28.4 5.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Sulfotransfer_3 PF13469.6 KDO33013.1 - 9.4e-14 52.3 0.6 2.9e-13 50.7 0.1 2.1 3 0 0 3 3 3 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KDO33013.1 - 3.5e-09 36.5 0.0 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Asp_Arg_Hydrox PF05118.15 KDO33013.1 - 8.1e-09 35.5 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF2076 PF09849.9 KDO33014.1 - 5.2e-05 23.4 7.8 7.3e-05 22.9 7.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 KDO33014.1 - 0.51 11.0 6.0 0.71 10.5 6.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIFIN PF02009.16 KDO33015.1 - 0.1 12.5 0.6 0.15 12.0 0.6 1.1 1 0 0 1 1 1 0 Rifin Thioredoxin PF00085.20 KDO33016.1 - 5.2e-20 71.4 0.0 6.7e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KDO33016.1 - 0.0087 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Maf PF02545.14 KDO33016.1 - 0.086 12.7 0.1 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 Maf-like protein Thioredoxin PF00085.20 KDO33017.1 - 6.9e-13 48.5 0.0 8.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 KDO33018.1 - 1.8e-25 88.9 0.0 2.4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KDO33018.1 - 1.5e-05 24.8 0.0 1.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KDO33018.1 - 5.3e-05 23.5 0.0 7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KDO33018.1 - 0.00029 20.3 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KDO33018.1 - 0.0021 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.21 KDO33018.1 - 0.0023 17.8 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KDO33018.1 - 0.0035 17.8 0.2 0.022 15.2 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KDO33018.1 - 0.081 12.6 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Redoxin Toxin-deaminase PF14424.6 KDO33018.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases HA PF03457.14 KDO33020.1 - 3.3e-14 53.0 0.0 0.0066 16.8 0.0 6.5 7 0 0 7 7 7 4 Helicase associated domain AA_permease_2 PF13520.6 KDO33021.1 - 2.9e-06 26.4 6.2 0.00013 20.9 5.8 2.2 1 1 1 2 2 2 2 Amino acid permease UCH PF00443.29 KDO33022.1 - 8e-38 130.4 0.0 1.1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO33022.1 - 6.9e-13 48.9 0.0 3e-12 46.8 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Bact_lectin PF18483.1 KDO33024.1 - 3.6e-11 43.5 0.0 1e-10 42.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KDO33024.1 - 2.6e-09 37.0 0.8 0.00024 20.7 0.0 3.1 3 1 0 3 3 3 2 Legume lectin domain Lectin_leg-like PF03388.13 KDO33024.1 - 0.011 15.1 0.0 6 6.1 0.0 2.6 2 2 0 2 2 2 0 Legume-like lectin family Myotub-related PF06602.14 KDO33025.1 - 3.6e-117 391.3 0.0 6.3e-117 390.4 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 KDO33025.1 - 4.1e-16 58.9 10.7 4.1e-16 58.9 10.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger C2 PF00168.30 KDO33025.1 - 1.7e-15 57.2 0.0 1e-14 54.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain Y_phosphatase3 PF13350.6 KDO33025.1 - 0.0033 17.4 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KDO33025.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KDO33025.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain IFP_35_N PF07334.13 KDO33025.1 - 0.71 10.0 1.9 5.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FYVE_2 PF02318.16 KDO33025.1 - 2.5 8.3 9.2 6.6 7.0 9.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger PRRSV_Env PF02340.15 KDO33026.1 - 0.11 11.9 0.6 0.14 11.5 0.6 1.1 1 0 0 1 1 1 0 PRRSV putative envelope protein Fer4_24 PF18109.1 KDO33027.1 - 0.25 11.6 1.1 2.4 8.5 0.2 2.2 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain MMR_HSR1 PF01926.23 KDO33029.1 - 4.2e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KDO33029.1 - 7.8e-05 22.8 0.6 0.00029 20.9 0.3 2.0 1 1 1 2 2 2 1 Dynamin family GBP PF02263.19 KDO33029.1 - 0.00014 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KDO33029.1 - 0.00064 18.0 0.0 0.0012 17.2 0.0 1.4 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) UB2H PF14814.6 KDO33030.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain CENP-B_N PF04218.13 KDO33031.1 - 0.02 14.5 0.6 1.8 8.3 0.1 2.4 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF4138 PF13595.6 KDO33031.1 - 0.13 11.5 0.4 0.18 11.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF3752 PF12572.8 KDO33031.1 - 0.73 10.3 16.1 7.9 7.0 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3752) DUF1690 PF07956.11 KDO33034.1 - 0.053 14.0 3.8 0.11 13.0 3.8 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF5598 PF18127.1 KDO33034.1 - 0.056 13.9 1.1 0.21 12.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5598) Apolipoprotein PF01442.18 KDO33034.1 - 0.45 10.4 11.7 0.048 13.5 6.6 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phasin PF05597.11 KDO33034.1 - 2.7 8.0 15.1 2.8 7.9 5.0 3.1 2 2 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RWP-RK PF02042.15 KDO33036.1 - 1.9e-19 69.3 1.4 1.3e-18 66.6 0.1 2.3 2 0 0 2 2 2 1 RWP-RK domain Arm PF00514.23 KDO33037.1 - 1.2e-12 47.4 28.7 7.7e-07 28.9 0.4 8.2 9 1 0 10 10 10 4 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KDO33037.1 - 3.6e-07 29.6 0.0 7.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 KDO33037.1 - 4.7e-06 27.0 3.1 1.3e-05 25.6 3.1 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 KDO33037.1 - 0.13 12.6 6.5 53 4.5 0.0 6.2 6 0 0 6 6 6 0 HEAT repeat FYVE_2 PF02318.16 KDO33038.1 - 0.31 11.3 12.2 0.92 9.7 12.2 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger eIF-3_zeta PF05091.12 KDO33039.1 - 4.1e-184 613.4 4.4 4.7e-184 613.2 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) La PF05383.17 KDO33040.1 - 8.5e-19 67.4 0.1 1.6e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KDO33040.1 - 1.8e-10 40.5 0.0 6e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 KDO33041.1 - 5.6e-08 33.0 1.2 5.6e-08 33.0 1.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33041.1 - 1.7e-06 27.7 0.3 0.042 14.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33041.1 - 7.8e-06 25.5 0.1 0.00083 19.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33041.1 - 0.0038 17.8 0.3 0.0038 17.8 0.3 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO33041.1 - 0.0067 15.8 1.3 0.0067 15.8 1.3 2.1 3 0 0 3 3 3 1 MalT-like TPR region RPN7 PF10602.9 KDO33041.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 KDO33041.1 - 0.03 14.3 0.0 2.5 8.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33041.1 - 0.047 14.2 0.4 0.047 14.2 0.4 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33041.1 - 0.095 13.0 1.0 9.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33041.1 - 1 10.2 5.5 1 10.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33041.1 - 1.2 10.1 6.1 33 5.7 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TMEM154 PF15102.6 KDO33042.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 KDO33042.1 - 0.0021 18.2 0.6 0.0037 17.4 0.6 1.3 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 KDO33042.1 - 0.14 12.6 8.5 0.25 11.8 8.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PRR18 PF15671.5 KDO33042.1 - 0.22 11.4 10.0 0.36 10.7 10.0 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 Oxysterol_BP PF01237.18 KDO33045.1 - 3.3e-21 75.5 0.0 5.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KDO33045.1 - 1e-12 48.5 0.0 2.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 PH domain START PF01852.19 KDO33045.1 - 1.3e-11 44.4 0.0 2.1e-10 40.4 0.0 2.6 2 1 0 2 2 2 1 START domain PH_11 PF15413.6 KDO33045.1 - 2.4e-05 24.7 0.6 7e-05 23.2 0.6 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KDO33045.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 KDO33045.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 PH domain Exo_endo_phos PF03372.23 KDO33046.1 - 2.6e-06 27.1 0.0 5.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IQ PF00612.27 KDO33046.1 - 1.5e-05 24.4 2.5 0.11 12.4 0.7 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif UPF0181 PF03701.14 KDO33046.1 - 0.068 12.8 0.6 0.16 11.6 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) HMMR_N PF15905.5 KDO33047.1 - 0.018 14.5 7.3 0.047 13.2 2.9 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CHASE3 PF05227.13 KDO33047.1 - 0.022 14.7 11.5 0.45 10.4 0.7 2.2 2 0 0 2 2 2 0 CHASE3 domain CENP-F_leu_zip PF10473.9 KDO33047.1 - 0.032 14.3 4.5 1.3 9.1 0.1 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KDO33047.1 - 0.036 14.1 6.7 0.75 9.8 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Lipoprotein_20 PF13942.6 KDO33047.1 - 0.047 13.6 6.8 0.43 10.5 0.2 2.3 2 0 0 2 2 2 0 YfhG lipoprotein BMFP PF04380.13 KDO33047.1 - 0.054 14.0 1.7 0.22 12.0 0.2 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity DUF5082 PF16888.5 KDO33047.1 - 0.072 13.4 5.8 4.3 7.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 KDO33047.1 - 0.079 13.1 5.8 1.5 8.9 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KDO33047.1 - 0.085 12.1 11.0 0.53 9.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cast PF10174.9 KDO33047.1 - 0.15 10.3 10.8 0.42 8.8 4.9 2.0 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone DASH_Dam1 PF08653.10 KDO33047.1 - 0.18 11.6 1.1 1.2 9.0 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Spc7 PF08317.11 KDO33047.1 - 0.2 10.5 6.4 0.71 8.7 6.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein GIT_CC PF16559.5 KDO33047.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor NPV_P10 PF05531.12 KDO33047.1 - 0.26 11.8 3.9 9.8 6.7 0.1 3.3 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 KDO33047.1 - 1.1 10.1 5.1 7.2 7.4 1.2 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prefoldin_2 PF01920.20 KDO33047.1 - 2.2 8.3 6.9 4.6 7.2 1.4 2.6 3 0 0 3 3 3 0 Prefoldin subunit DUF2730 PF10805.8 KDO33047.1 - 3.1 7.9 7.2 15 5.7 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Mcp5_PH PF12814.7 KDO33049.1 - 0.0035 17.4 0.3 0.0059 16.7 0.3 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Amino_oxidase PF01593.24 KDO33050.1 - 5e-17 62.3 0.1 2.3e-16 60.1 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KDO33050.1 - 8.7e-13 48.3 2.3 9.6e-13 48.2 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KDO33050.1 - 4.2e-06 26.6 3.0 0.00012 21.8 2.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO33050.1 - 1.3e-05 24.4 2.5 0.00012 21.4 1.8 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KDO33050.1 - 4e-05 22.5 0.5 0.06 12.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KDO33050.1 - 9.1e-05 21.8 0.0 0.004 16.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KDO33050.1 - 0.00028 20.4 1.1 0.0037 16.7 1.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 KDO33050.1 - 0.0021 16.7 0.0 0.26 9.8 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Pyr_redox PF00070.27 KDO33050.1 - 0.0024 18.4 0.9 0.042 14.4 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO33050.1 - 0.0035 16.6 0.1 0.007 15.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KDO33050.1 - 0.0084 15.4 1.5 0.015 14.6 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KDO33050.1 - 0.013 14.6 2.5 0.2 10.7 1.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KDO33050.1 - 0.022 13.8 0.2 1 8.4 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AbiEii PF08843.11 KDO33051.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system CCDC66 PF15236.6 KDO33052.1 - 0.71 9.7 37.2 0.074 12.9 28.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 YqhG PF11079.8 KDO33052.1 - 8.4 5.3 8.5 13 4.6 8.5 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Dynein_light PF01221.18 KDO33053.1 - 7.2e-26 90.3 0.5 8.3e-26 90.1 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Choline_transpo PF04515.12 KDO33054.1 - 1.7e-100 336.4 29.5 1.7e-100 336.4 29.5 3.3 3 1 0 3 3 3 1 Plasma-membrane choline transporter AveC_like PF17198.4 KDO33054.1 - 0.011 15.2 2.8 0.011 15.2 2.8 2.8 3 1 0 3 3 3 0 Spirocyclase AveC-like Cytokin_check_N PF10407.9 KDO33055.1 - 0.0014 18.6 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus Arm PF00514.23 KDO33055.1 - 0.049 13.7 8.9 8.3 6.6 0.1 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TPR_1 PF00515.28 KDO33056.1 - 6.6e-21 73.2 11.2 3.1e-09 36.2 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 KDO33056.1 - 6.2e-18 64.5 27.2 5e-14 52.0 1.2 2.7 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 KDO33056.1 - 3.6e-16 57.9 14.1 1.5e-06 27.8 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33056.1 - 1.2e-12 46.9 9.3 2.7e-06 27.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33056.1 - 1.4e-11 43.8 12.8 8.1e-05 22.2 0.1 4.7 2 1 2 4 4 4 3 TPR repeat TPR_7 PF13176.6 KDO33056.1 - 4.4e-11 42.0 3.4 0.0001 22.0 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33056.1 - 2.1e-09 37.4 7.2 3.4e-05 24.3 0.1 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33056.1 - 1.4e-07 31.4 1.3 0.0011 19.2 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33056.1 - 3.4e-07 30.5 7.1 9.4e-06 25.8 0.9 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat SGTA_dimer PF16546.5 KDO33056.1 - 5.5e-07 29.3 0.7 1.1e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_19 PF14559.6 KDO33056.1 - 1.3e-05 25.6 6.5 0.00012 22.5 0.5 4.1 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33056.1 - 1.7e-05 25.3 6.6 0.024 15.3 0.6 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat SGT1 PF07093.11 KDO33056.1 - 0.00024 19.7 0.2 0.00033 19.2 0.2 1.2 1 0 0 1 1 1 1 SGT1 protein TPR_9 PF13371.6 KDO33056.1 - 0.00098 19.2 0.2 0.0067 16.6 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO33056.1 - 0.0016 18.2 6.3 1.5 8.8 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat GerD PF17898.1 KDO33056.1 - 0.0047 16.9 8.4 0.0076 16.2 6.3 2.3 2 0 0 2 2 2 1 Spore germination GerD central core domain XPC-binding PF09280.11 KDO33056.1 - 0.018 14.8 12.4 0.12 12.2 3.4 3.7 3 1 1 4 4 4 0 XPC-binding domain BTAD PF03704.17 KDO33056.1 - 0.019 15.4 3.3 0.24 11.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KDO33056.1 - 0.2 12.4 5.9 1.1 10.1 0.1 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KDO33056.1 - 0.33 11.0 4.3 5.3 7.1 1.8 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DUF4199 PF13858.6 KDO33056.1 - 1.4 9.3 4.2 0.32 11.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) MIT PF04212.18 KDO33056.1 - 1.7 8.8 8.7 9.2 6.4 2.2 3.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain MAM33 PF02330.16 KDO33057.1 - 3.2e-42 144.9 7.9 3.7e-42 144.7 7.9 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein SNF2_N PF00176.23 KDO33058.1 - 3.1e-66 223.5 0.4 6.9e-66 222.3 0.4 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KDO33058.1 - 1.1e-18 67.1 0.0 2.8e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KDO33058.1 - 2e-18 66.7 0.0 6e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO33058.1 - 2.6e-10 40.6 0.1 2e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 KDO33058.1 - 2.1e-09 37.5 7.1 2.1e-09 37.5 7.1 2.3 2 0 0 2 2 2 1 HSA SnAC PF14619.6 KDO33058.1 - 1.3e-07 32.2 0.1 6.3e-07 29.9 0.1 2.3 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.29 KDO33058.1 - 2.3e-06 27.5 0.0 6.6e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KDO33058.1 - 0.00032 20.4 0.0 0.00089 19.0 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KDO33058.1 - 0.0017 17.6 0.0 0.024 13.8 0.0 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 COMP PF11598.8 KDO33058.1 - 1.3 9.6 4.6 18 5.9 0.0 4.0 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein Metallophos PF00149.28 KDO33059.1 - 3e-30 106.3 0.1 4e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KDO33059.1 - 0.21 12.1 0.1 0.56 10.7 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Histidinol_dh PF00815.20 KDO33061.1 - 2.9e-123 411.9 7.6 3.5e-123 411.6 7.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Sulfate_transp PF00916.20 KDO33062.1 - 7e-79 265.3 18.9 2e-41 142.0 9.7 2.2 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 KDO33062.1 - 6.4e-10 38.7 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain Saf_2TM PF18303.1 KDO33062.1 - 0.042 13.4 0.3 0.042 13.4 0.3 3.6 3 1 2 5 5 5 0 SAVED-fused 2TM effector domain BIV_Env PF05858.12 KDO33062.1 - 0.077 11.2 0.1 0.14 10.3 0.1 1.3 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) E7R PF17467.2 KDO33062.1 - 0.19 11.9 1.8 0.27 11.4 0.5 1.9 2 0 0 2 2 2 0 Viral Protein E7 Sulfate_transp PF00916.20 KDO33063.1 - 2.4e-78 263.5 21.5 2e-40 138.7 8.8 2.2 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 KDO33063.1 - 4.2e-10 39.3 0.0 7.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KDO33063.1 - 1.6e-05 25.2 0.7 3.5e-05 24.1 0.7 1.5 1 0 0 1 1 1 1 STAS domain BIV_Env PF05858.12 KDO33063.1 - 0.087 11.0 0.2 0.15 10.2 0.2 1.3 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Pkr1 PF08636.10 KDO33063.1 - 0.11 12.7 7.9 0.054 13.6 3.4 2.8 2 0 0 2 2 2 0 ER protein Pkr1 Cytochrome-c551 PF10643.9 KDO33063.1 - 2.3 7.8 7.3 6 6.4 1.5 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 CI-B14_5a PF07347.12 KDO33065.1 - 0.2 11.5 1.5 0.33 10.9 0.6 1.8 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) RRM_1 PF00076.22 KDO33066.1 - 4.1e-07 29.7 0.0 6.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KDO33066.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_S46 PF10459.9 KDO33067.1 - 0.086 11.5 17.0 0.1 11.2 17.0 1.0 1 0 0 1 1 1 0 Peptidase S46 U1snRNP70_N PF12220.8 KDO33067.1 - 0.12 13.0 0.3 0.12 13.0 0.3 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Lzipper-MIP1 PF14389.6 KDO33067.1 - 0.33 11.3 23.3 1.4 9.3 0.3 3.9 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 UPF0147 PF03685.13 KDO33067.1 - 1 9.5 5.3 0.27 11.3 0.3 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) MscS_porin PF12795.7 KDO33067.1 - 1.1 8.7 34.5 5.1 6.6 20.1 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain HLH PF00010.26 KDO33067.1 - 1.7 8.7 5.7 0.3 11.1 0.8 2.2 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain ERp29 PF07749.12 KDO33067.1 - 3.1 8.7 11.2 0.86 10.5 1.2 3.1 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain FliJ PF02050.16 KDO33067.1 - 4.5 7.5 30.2 12 6.1 14.8 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein AP1AR PF15745.5 KDO33067.1 - 7.5 6.1 17.3 0.43 10.2 11.5 1.7 1 1 1 2 2 2 0 AP-1 complex-associated regulatory protein Pepdidase_M14_N PF18027.1 KDO33068.1 - 5.8e-13 49.1 0.6 1e-12 48.4 0.6 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KDO33068.1 - 2e-12 47.5 0.0 6.9e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF4611 PF15387.6 KDO33068.1 - 0.67 10.2 3.5 1.2 9.4 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ion_trans PF00520.31 KDO33070.1 - 2.5e-32 112.1 19.1 4.5e-18 65.4 7.6 3.2 3 0 0 3 3 3 3 Ion transport protein Ion_trans_2 PF07885.16 KDO33070.1 - 4.4e-16 58.6 24.0 1.7e-09 37.5 3.7 3.2 3 0 0 3 3 3 2 Ion channel IRK PF01007.20 KDO33070.1 - 0.7 9.7 5.3 8.8 6.1 1.1 3.1 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain LRR_4 PF12799.7 KDO33071.1 - 0.00032 21.0 1.2 6.9 7.2 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO33071.1 - 0.13 12.9 0.7 44 5.2 0.0 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_2 PF07723.13 KDO33071.1 - 0.28 11.9 3.6 49 4.8 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat PsbM PF05151.12 KDO33072.1 - 0.044 13.6 0.9 0.1 12.4 0.9 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) LRR_4 PF12799.7 KDO33072.1 - 0.16 12.5 0.8 3.9 8.0 0.1 3.3 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) Peptidase_M48_N PF16491.5 KDO33073.1 - 2.9e-63 213.0 0.6 2.9e-63 213.0 0.6 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KDO33073.1 - 1.6e-43 148.8 0.0 2.3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 KDO33073.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Ion_trans PF00520.31 KDO33074.1 - 7.9e-41 139.9 27.5 7.9e-22 77.7 15.2 2.7 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 KDO33074.1 - 2.7e-17 62.5 22.3 1.2e-09 38.0 1.3 3.0 3 0 0 3 3 3 2 Ion channel 2OG-FeII_Oxy_3 PF13640.6 KDO33075.1 - 0.00042 21.1 0.0 0.00076 20.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMEM154 PF15102.6 KDO33076.1 - 0.018 14.9 0.9 0.029 14.3 0.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family Trp_oprn_chp PF09534.10 KDO33076.1 - 0.022 14.5 0.4 0.022 14.5 0.4 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 KDO33076.1 - 0.03 14.4 0.3 0.046 13.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Kinesin PF00225.23 KDO33077.1 - 5.3e-09 35.5 0.0 6.1e-08 32.0 0.0 2.4 1 1 1 2 2 2 1 Kinesin motor domain TPR_MLP1_2 PF07926.12 KDO33077.1 - 6.2e-06 26.3 7.7 6.2e-06 26.3 7.7 4.7 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KDO33077.1 - 0.00033 20.9 1.2 0.00033 20.9 1.2 4.1 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Microtub_bd PF16796.5 KDO33077.1 - 0.031 14.2 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Microtubule binding AAA_28 PF13521.6 KDO33077.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain Csm2_III-A PF03750.13 KDO33077.1 - 4.9 8.0 8.4 0.21 12.4 0.5 2.8 2 1 0 3 3 3 0 Csm2 Type III-A Fib_alpha PF08702.10 KDO33077.1 - 5.4 7.2 26.5 1.2 9.4 4.7 4.0 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KDO33077.1 - 6.7 6.0 40.0 4.9 6.5 6.0 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding zf-MYND PF01753.18 KDO33078.1 - 2.2e-10 40.4 12.3 4.5e-10 39.5 12.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KDO33078.1 - 0.0068 16.7 8.0 0.014 15.7 8.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KDO33078.1 - 1.7 8.5 9.3 3.1 7.7 9.3 1.4 1 0 0 1 1 1 0 HIT zinc finger TPR_16 PF13432.6 KDO33079.1 - 0.0013 19.3 0.2 0.0013 19.3 0.2 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33079.1 - 0.047 14.5 12.5 4.6 8.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33079.1 - 0.056 13.9 9.2 0.38 11.3 1.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33079.1 - 0.1 12.8 4.8 8.8 6.7 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO33079.1 - 2.2 8.6 0.0 2.2 8.6 0.0 4.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Med20 PF08612.11 KDO33080.1 - 7.3e-06 25.5 0.0 9.4e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Hol_Tox PF16935.5 KDO33080.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) DBD_Tnp_Mut PF03108.15 KDO33081.1 - 2.2e-06 27.6 0.0 4.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase TilS PF09179.11 KDO33081.1 - 0.092 13.3 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 TilS substrate binding domain Peptidase_S10 PF00450.22 KDO33082.1 - 6.3e-130 434.3 2.3 7.4e-130 434.1 2.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DEAD PF00270.29 KDO33083.1 - 1.8e-19 70.2 0.0 2.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KDO33083.1 - 4.9e-15 56.0 5.0 4.9e-15 56.0 5.0 2.0 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 KDO33083.1 - 2.8e-11 43.7 0.0 2.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO33083.1 - 0.00027 21.0 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TIR_2 PF13676.6 KDO33084.1 - 1.9e-11 44.6 0.0 3.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain SAM_2 PF07647.17 KDO33084.1 - 2.8e-07 30.5 0.1 5.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO33084.1 - 8.3e-06 26.2 0.1 3.1e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HI0933_like PF03486.14 KDO33084.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein KIF1B PF12423.8 KDO33085.1 - 0.079 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Kinesin protein 1B TatD_DNase PF01026.21 KDO33086.1 - 1.2e-55 188.6 0.0 1.4e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase EarP PF10093.9 KDO33087.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP DUF905 PF06006.12 KDO33089.1 - 0.41 10.7 2.4 1.2 9.2 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) IQ PF00612.27 KDO33089.1 - 2.6 8.1 17.3 0.16 11.8 0.7 4.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif Aminotran_4 PF01063.19 KDO33090.1 - 1.6e-27 96.8 0.0 2e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF1515 PF07439.11 KDO33091.1 - 1.4 9.0 13.2 1.2 9.2 3.6 4.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF2353 PF09789.9 KDO33092.1 - 0.00021 20.8 0.4 0.058 12.8 0.6 2.2 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) TMF_TATA_bd PF12325.8 KDO33092.1 - 0.0094 16.2 0.4 0.023 14.9 0.2 1.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding CCDC92 PF14916.6 KDO33092.1 - 0.034 13.9 2.5 2.9 7.7 0.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain of unknown function bZIP_2 PF07716.15 KDO33092.1 - 0.037 14.1 5.8 0.1 12.7 1.3 3.1 3 0 0 3 3 3 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 KDO33092.1 - 0.04 14.2 0.6 2.4 8.5 1.2 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain GIT_CC PF16559.5 KDO33092.1 - 0.067 13.1 6.9 0.36 10.7 1.0 3.3 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor E2F_CC-MB PF16421.5 KDO33092.1 - 0.067 13.5 3.3 1.4 9.3 3.3 2.3 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain GAS PF13851.6 KDO33092.1 - 0.073 12.4 4.6 0.075 12.4 3.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Nuc_N PF14448.6 KDO33092.1 - 0.074 12.9 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Nuclease N terminal SOGA PF11365.8 KDO33092.1 - 0.12 13.5 1.6 0.31 12.2 1.0 2.0 2 0 0 2 2 1 0 Protein SOGA YlqD PF11068.8 KDO33092.1 - 0.15 12.5 2.6 0.28 11.5 2.6 1.4 1 0 0 1 1 1 0 YlqD protein Cnn_1N PF07989.11 KDO33092.1 - 0.17 12.0 1.1 0.53 10.5 0.5 2.1 2 1 0 2 2 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KDO33092.1 - 0.21 12.3 1.9 3.8 8.2 2.0 2.6 2 1 0 2 2 2 0 Initiation control protein YabA DUF1843 PF08898.10 KDO33092.1 - 0.31 11.5 3.2 0.22 12.0 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) TolA_bind_tri PF16331.5 KDO33092.1 - 0.83 9.8 10.5 0.27 11.3 1.8 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation DivIC PF04977.15 KDO33092.1 - 1.3 8.8 5.9 2.6 7.9 0.5 3.0 2 1 1 3 3 3 0 Septum formation initiator Ank_2 PF12796.7 KDO33093.1 - 0.00035 21.1 0.1 0.0011 19.5 0.1 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33093.1 - 0.0023 18.4 0.0 1 10.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33093.1 - 0.0092 16.3 0.0 0.069 13.5 0.0 2.5 1 1 3 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33093.1 - 0.021 15.3 0.0 0.5 11.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KDO33096.1 - 2.9e-05 24.6 0.0 0.00072 20.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33096.1 - 0.0017 18.6 0.1 1.5 9.3 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO33096.1 - 0.0057 17.2 0.0 4.9 7.9 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF5049 PF16468.5 KDO33096.1 - 0.17 11.8 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) Ank_2 PF12796.7 KDO33097.1 - 0.00053 20.5 0.1 0.0013 19.2 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33097.1 - 0.0018 18.8 0.3 0.14 12.8 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33097.1 - 0.0026 18.0 0.1 0.36 11.2 0.0 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33097.1 - 0.021 15.3 0.3 5.5 7.9 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat EF-hand_1 PF00036.32 KDO33098.1 - 3.4e-10 38.7 1.4 0.00018 20.9 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KDO33098.1 - 1.1e-09 37.4 0.7 0.0026 17.6 0.1 3.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 KDO33098.1 - 5.6e-09 36.3 0.9 1.7e-07 31.6 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO33098.1 - 2.2e-07 30.0 1.0 0.028 13.9 0.1 2.9 2 0 0 2 2 2 2 EF hand MIP-T3 PF10243.9 KDO33098.1 - 4.8e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain EF-hand_8 PF13833.6 KDO33098.1 - 5.9e-06 26.0 0.0 5.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 KDO33098.1 - 5.4e-05 23.4 0.2 0.27 11.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain Bac_RepA_C PF18008.1 KDO33098.1 - 0.032 14.6 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain IQ PF00612.27 KDO33098.1 - 0.15 12.0 0.5 0.56 10.2 0.5 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Seryl_tRNA_N PF02403.22 KDO33098.1 - 0.18 12.0 1.9 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SNF2_N PF00176.23 KDO33099.1 - 2e-61 207.7 0.3 5.3e-61 206.3 0.3 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-HC5HC2H_2 PF13832.6 KDO33099.1 - 7.7e-20 71.1 16.2 1e-19 70.7 5.3 3.5 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO33099.1 - 2.2e-16 59.9 3.3 2.2e-16 59.9 3.3 3.1 3 1 0 3 3 3 1 PHD-like zinc-binding domain Chromo PF00385.24 KDO33099.1 - 8.5e-16 57.6 0.0 6.9e-09 35.5 0.0 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KDO33099.1 - 3.6e-13 49.8 0.0 1.3e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO33099.1 - 1.9e-09 37.7 0.1 8.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 KDO33099.1 - 7.3e-09 35.0 7.6 7.3e-09 35.0 7.6 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KDO33099.1 - 1e-05 25.3 13.0 1e-05 25.3 13.0 2.8 2 0 0 2 2 2 1 PHD-finger QLQ PF08880.11 KDO33099.1 - 7.1e-05 22.5 1.2 0.00013 21.7 0.0 2.1 2 0 0 2 2 2 1 QLQ DEAD PF00270.29 KDO33099.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase PDZ_2 PF13180.6 KDO33099.1 - 0.012 15.9 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 0 PDZ domain TPR_2 PF07719.17 KDO33100.1 - 1.1e-07 31.4 8.8 0.00019 21.3 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33100.1 - 1.1e-06 28.2 3.8 0.0011 18.6 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33100.1 - 8.1e-06 26.0 8.4 0.0013 19.0 0.2 3.5 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33100.1 - 1.5e-05 25.0 0.2 1.4 9.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33100.1 - 4.7e-05 23.3 0.3 0.19 12.0 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33100.1 - 8e-05 23.2 16.8 0.099 13.5 0.2 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33100.1 - 0.0011 18.8 2.1 0.039 14.0 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33100.1 - 0.0028 18.3 23.2 0.085 13.5 5.8 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33100.1 - 0.0052 16.4 5.8 0.74 9.5 0.1 3.6 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 KDO33100.1 - 0.0094 16.1 3.1 0.37 11.0 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.12 KDO33100.1 - 0.0095 16.6 0.1 0.0095 16.6 0.1 3.4 4 0 0 4 4 3 1 Sel1 repeat DUF4810 PF16068.5 KDO33100.1 - 0.13 12.8 0.0 4.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) Asp PF00026.23 KDO33101.1 - 5.4e-32 111.5 0.9 3.6e-31 108.8 0.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO33101.1 - 2.8e-05 24.5 3.3 0.024 14.9 0.5 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO33101.1 - 0.015 15.1 0.0 0.058 13.2 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KDO33101.1 - 0.036 14.6 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KDO33101.1 - 0.073 13.7 0.1 1.1 9.9 0.1 2.5 2 0 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KDO33102.1 - 6.4e-28 98.1 2.2 1.3e-26 93.8 2.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO33102.1 - 2e-05 24.9 3.8 0.039 14.2 0.3 2.4 1 1 0 2 2 2 2 Xylanase inhibitor N-terminal Acyltransferase PF01553.21 KDO33103.1 - 1.1e-10 41.3 0.0 3.8e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Ank_2 PF12796.7 KDO33104.1 - 1.6e-11 44.7 4.5 1.1e-06 29.1 0.7 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33104.1 - 9.8e-05 22.8 0.9 0.019 15.6 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33104.1 - 0.00075 19.8 0.8 6.7 7.6 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KDO33104.1 - 0.0092 16.3 0.2 3.5 8.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO33104.1 - 0.57 10.7 2.8 69 4.1 0.0 3.5 2 1 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KDO33105.1 - 7.7e-05 23.2 3.2 0.01 16.4 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO33105.1 - 0.00034 21.2 0.2 0.0006 20.4 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33105.1 - 0.0047 17.2 0.1 0.013 15.8 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33105.1 - 0.044 14.3 2.0 20 6.2 0.0 3.9 3 1 1 4 4 4 0 Ankyrin repeat ADH_zinc_N PF00107.26 KDO33106.1 - 2.4e-16 59.9 0.0 3.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO33106.1 - 2.1e-09 38.5 0.0 2.7e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KDO33106.1 - 0.0061 15.9 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 KDO33107.1 - 4.7e-26 90.8 4.9 8e-26 90.1 4.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KDO33107.1 - 3e-19 69.3 0.0 5.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO33107.1 - 8.3e-09 36.6 0.0 1.2e-08 36.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KDO33107.1 - 2e-06 27.3 0.0 3.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KDO33107.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ten1_2 PF15490.6 KDO33108.1 - 2.2e-25 88.7 0.2 2.4e-25 88.5 0.2 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit SLBP_RNA_bind PF15247.6 KDO33109.1 - 2.3e-30 104.5 1.8 2.3e-30 104.5 1.8 2.6 2 1 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain DUF2457 PF10446.9 KDO33109.1 - 0.074 12.2 32.7 0.12 11.5 32.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prefoldin_2 PF01920.20 KDO33111.1 - 2.9e-19 69.0 13.9 3.5e-19 68.7 13.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Rh5 PF18515.1 KDO33111.1 - 0.022 14.1 2.3 0.026 13.8 2.3 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain HDV_ag PF01517.18 KDO33111.1 - 0.035 13.9 0.3 0.057 13.2 0.2 1.4 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen PRKG1_interact PF15898.5 KDO33111.1 - 0.039 14.9 7.1 0.066 14.1 7.1 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 KDO33111.1 - 0.42 10.7 7.1 0.19 11.7 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 KDO33111.1 - 0.68 9.9 13.7 5.7 6.9 13.7 2.1 1 1 0 1 1 1 0 Prefoldin subunit PEARLI-4 PF05278.12 KDO33111.1 - 0.8 9.2 8.7 0.44 10.1 6.2 1.6 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Prefoldin_3 PF13758.6 KDO33111.1 - 0.89 9.6 8.2 0.18 11.9 4.5 1.8 2 1 0 2 2 2 0 Prefoldin subunit Ribosomal_60s PF00428.19 KDO33111.1 - 1.4 9.6 11.2 0.06 13.9 5.7 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein FlaC_arch PF05377.11 KDO33111.1 - 5.7 7.4 10.2 4.1 7.9 3.3 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Gaa1 PF04114.14 KDO33112.1 - 1.1e-69 235.8 10.9 4.7e-64 217.2 0.1 2.6 3 0 0 3 3 3 2 Gaa1-like, GPI transamidase component PKD_channel PF08016.12 KDO33114.1 - 3e-46 158.0 1.6 4.8e-46 157.3 1.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KDO33114.1 - 9.8e-10 38.1 12.5 1.6e-09 37.4 12.5 1.3 1 0 0 1 1 1 1 Ion transport protein SlyX PF04102.12 KDO33114.1 - 0.053 14.1 0.5 0.13 12.9 0.5 1.6 1 0 0 1 1 1 0 SlyX DUF3724 PF12521.8 KDO33114.1 - 0.15 12.0 0.9 0.52 10.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) YafO_toxin PF13957.6 KDO33114.1 - 0.19 11.8 1.0 0.89 9.6 0.1 2.4 2 0 0 2 2 2 0 Toxin YafO, type II toxin-antitoxin system GPR_Gpa2_C PF11970.8 KDO33114.1 - 0.47 10.6 5.5 0.82 9.8 0.3 3.0 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Mg_trans_NIPA PF05653.14 KDO33115.1 - 2.7e-31 108.8 12.9 4.5e-30 104.8 12.9 2.1 1 1 0 1 1 1 1 Magnesium transporter NIPA Fz PF01392.22 KDO33115.1 - 7.1e-05 23.4 10.1 0.00012 22.6 10.1 1.3 1 0 0 1 1 1 1 Fz domain EamA PF00892.20 KDO33115.1 - 0.014 15.6 8.4 0.014 15.6 8.4 3.6 3 1 0 3 3 3 0 EamA-like transporter family DUF5453 PF17534.2 KDO33115.1 - 0.2 11.6 4.9 1.3 9.0 4.3 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5453) DUF3671 PF12420.8 KDO33115.1 - 0.61 10.2 3.2 0.51 10.4 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF2304 PF10066.9 KDO33115.1 - 1.3 9.3 6.1 0.87 9.8 3.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pkinase_Tyr PF07714.17 KDO33118.1 - 2.3e-38 132.0 0.0 3.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO33118.1 - 3.4e-36 124.9 0.0 4.8e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 KDO33118.1 - 4e-06 27.1 5.8 6.9e-05 23.1 0.5 3.2 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO33118.1 - 1.1e-05 25.1 0.7 1.1e-05 25.1 0.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 KDO33118.1 - 0.028 14.9 1.0 57 4.9 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO33118.1 - 0.08 13.0 5.1 0.55 10.4 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat stn_TNFRSF12A PF12191.8 KDO33118.1 - 0.14 12.3 1.3 0.41 10.9 0.2 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain ATG16 PF08614.11 KDO33120.1 - 1e-05 25.9 5.9 1e-05 25.9 5.9 4.6 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KDO33120.1 - 0.00035 20.6 0.4 0.00035 20.6 0.4 5.6 6 1 1 7 7 7 2 bZIP transcription factor DUF4200 PF13863.6 KDO33120.1 - 0.0095 16.3 11.5 0.0095 16.3 11.5 4.9 3 1 2 5 5 5 1 Domain of unknown function (DUF4200) Img2 PF05046.14 KDO33120.1 - 0.17 12.2 0.0 0.71 10.2 0.0 2.1 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) TMCO5 PF14992.6 KDO33120.1 - 0.76 9.3 30.1 2.7 7.5 1.0 2.6 2 1 0 2 2 2 0 TMCO5 family FAM76 PF16046.5 KDO33120.1 - 1.8 7.9 28.1 0.86 8.9 14.6 3.2 3 0 0 3 3 3 0 FAM76 protein V-ATPase_H_N PF03224.14 KDO33121.1 - 0.0032 16.8 0.0 0.0095 15.3 0.0 1.7 2 1 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 KDO33121.1 - 0.082 13.0 0.3 0.082 13.0 0.3 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Osmo_MPGsynth PF09488.10 KDO33121.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) LRR_6 PF13516.6 KDO33122.1 - 3.5e-05 23.5 5.5 3.7 7.9 0.0 5.9 5 0 0 5 5 5 4 Leucine Rich repeat Ank_2 PF12796.7 KDO33123.1 - 4.3e-28 97.7 4.2 2.9e-14 53.4 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33123.1 - 1.3e-26 92.3 6.1 1.4e-13 50.7 0.4 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO33123.1 - 1.8e-24 85.8 1.2 9.9e-12 45.1 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO33123.1 - 2.4e-21 75.1 1.4 8.9e-07 29.1 0.3 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KDO33123.1 - 7.4e-18 62.8 0.9 0.00047 20.4 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat FAM167 PF11652.8 KDO33124.1 - 0.0098 16.4 2.3 1.2 9.7 0.5 3.2 2 0 0 2 2 2 2 FAM167 DUF3381 PF11861.8 KDO33124.1 - 0.095 12.5 1.1 0.23 11.3 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF1328 PF07043.13 KDO33125.1 - 0.12 12.6 7.5 2.4 8.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) FBPase PF00316.20 KDO33127.1 - 4.4e-67 225.2 0.0 5.8e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KDO33127.1 - 0.0084 15.7 0.0 0.028 14.0 0.0 1.7 2 0 0 2 2 2 1 Inositol monophosphatase family Bud13 PF09736.9 KDO33129.1 - 2.9e-43 147.7 8.6 2.9e-43 147.7 8.6 1.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Hep_59 PF07052.11 KDO33130.1 - 8.4e-08 32.9 0.2 8.4e-08 32.9 0.2 2.7 2 1 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF3568 PF12092.8 KDO33130.1 - 0.2 11.7 0.8 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) DUF4085 PF13315.6 KDO33130.1 - 0.23 11.1 2.4 0.21 11.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Mito_carr PF00153.27 KDO33131.1 - 1.3e-48 162.8 6.6 2.5e-16 59.3 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Flavokinase PF01687.17 KDO33132.1 - 1.4e-21 76.9 0.0 1.6e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Tub PF01167.18 KDO33133.1 - 1.9e-39 135.9 0.0 1.5e-38 132.9 0.0 1.9 1 1 0 1 1 1 1 Tub family PDZ PF00595.24 KDO33133.1 - 0.00066 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO33133.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO33133.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Trypsin_2 PF13365.6 KDO33134.1 - 8.2e-06 26.8 0.0 1.2e-05 26.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Elicitin PF00964.17 KDO33135.1 - 9.1e-08 32.1 8.0 0.00011 22.3 1.1 2.2 2 0 0 2 2 2 2 Elicitin zf-C2HC_2 PF13913.6 KDO33136.1 - 8.7e-11 41.5 11.9 1.3e-08 34.5 3.8 3.6 4 0 0 4 4 4 2 zinc-finger of a C2HC-type c-SKI_SMAD_bind PF08782.10 KDO33136.1 - 0.11 12.8 6.2 0.23 11.7 0.1 2.7 2 1 0 2 2 2 0 c-SKI Smad4 binding domain Cytochrom_c3_2 PF14537.6 KDO33136.1 - 0.23 11.9 5.9 0.49 10.9 5.2 2.1 1 1 0 1 1 1 0 Cytochrome c3 Cytochrom_CIII PF02085.16 KDO33136.1 - 0.25 11.7 11.2 0.34 11.3 1.4 2.6 3 0 0 3 3 3 0 Class III cytochrome C family Cytochrome_C7 PF14522.6 KDO33136.1 - 2.1 8.4 9.0 23 5.1 9.0 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c AAA_6 PF12774.7 KDO33137.1 - 2.8e-137 457.1 0.0 8e-74 248.5 0.0 2.7 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO33137.1 - 4.6e-104 348.7 1.6 4.6e-104 348.7 1.6 3.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO33137.1 - 3.3e-84 282.3 0.0 1.6e-83 280.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KDO33137.1 - 4.5e-78 262.6 2.5 7e-78 261.9 0.0 2.5 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 KDO33137.1 - 2.4e-73 247.2 16.8 4.3e-73 246.3 16.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KDO33137.1 - 2.2e-66 223.1 0.8 9.8e-59 198.1 0.2 2.7 2 0 0 2 2 2 2 ATP-binding dynein motor region AAA_7 PF12775.7 KDO33137.1 - 4e-66 222.0 0.4 3.8e-58 196.0 0.0 4.1 4 0 0 4 4 3 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 KDO33137.1 - 7.3e-40 135.8 0.0 6.2e-35 119.9 0.0 4.8 4 1 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KDO33137.1 - 2e-38 131.8 0.0 4.5e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO33137.1 - 1.8e-22 79.4 0.0 6.8e-22 77.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KDO33137.1 - 2.4e-21 76.2 0.0 4.6e-09 36.4 0.0 5.5 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) DHC_N1 PF08385.12 KDO33137.1 - 2.7e-16 59.4 2.1 7.6e-16 57.9 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 KDO33137.1 - 2.1e-07 31.5 2.0 0.46 10.8 0.0 6.3 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.29 KDO33137.1 - 4.2e-07 30.5 2.6 0.87 10.0 0.0 4.7 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO33137.1 - 6.5e-07 29.9 0.3 0.67 10.5 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 KDO33137.1 - 1.4e-06 28.6 0.0 0.39 10.9 0.0 4.4 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KDO33137.1 - 4.1e-05 23.0 0.3 0.57 9.5 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KDO33137.1 - 4.5e-05 23.3 0.0 1 9.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KDO33137.1 - 0.00011 22.5 4.2 0.64 10.3 0.0 4.8 5 0 0 5 5 3 1 AAA domain SRP54 PF00448.22 KDO33137.1 - 0.00072 19.2 3.4 1.4 8.5 0.0 4.3 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KDO33137.1 - 0.0011 19.4 0.0 16 6.0 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 KDO33137.1 - 0.002 17.8 3.4 1.2 8.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 KDO33137.1 - 0.0027 17.7 2.7 3.6 7.6 0.0 4.4 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KDO33137.1 - 0.0043 16.1 0.0 1.4 7.9 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KDO33137.1 - 0.0068 16.2 1.1 18 5.0 0.0 4.5 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KDO33137.1 - 0.007 16.1 16.1 0.11 12.2 0.0 4.5 5 0 0 5 5 3 2 AAA domain ABC_tran PF00005.27 KDO33137.1 - 0.0074 16.8 0.2 1.5 9.3 0.0 3.6 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 KDO33137.1 - 0.0083 15.8 2.2 3.1 7.6 0.0 4.4 4 0 0 4 4 4 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KDO33137.1 - 0.01 15.6 0.0 0.71 9.5 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 KDO33137.1 - 0.011 15.7 3.2 0.24 11.3 0.0 3.8 4 0 0 4 4 3 0 NACHT domain AAA_19 PF13245.6 KDO33137.1 - 0.011 16.0 11.5 0.091 13.1 0.0 4.6 5 0 0 5 5 3 0 AAA domain cobW PF02492.19 KDO33137.1 - 0.013 15.1 0.2 2 8.0 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KDO33137.1 - 0.016 14.4 0.3 6.7 5.8 0.0 3.4 3 0 0 3 3 3 0 NB-ARC domain Dynein_AAA_lid PF17852.1 KDO33137.1 - 0.028 14.5 0.2 1.1 9.3 0.2 2.8 1 1 0 1 1 1 0 Dynein heavy chain AAA lid domain Roc PF08477.13 KDO33137.1 - 0.038 14.2 0.5 9.1 6.5 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KDO33137.1 - 0.043 14.0 10.2 0.74 10.0 0.0 4.5 5 0 0 5 5 3 0 AAA domain PhoH PF02562.16 KDO33137.1 - 0.12 11.8 0.9 2.6 7.4 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein PduV-EutP PF10662.9 KDO33137.1 - 0.15 11.8 2.0 13 5.5 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF948 PF06103.11 KDO33137.1 - 0.33 11.2 7.5 2.5 8.4 0.9 4.2 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) HNOBA PF07701.14 KDO33137.1 - 0.35 10.3 8.1 0.034 13.6 1.8 2.5 2 0 0 2 2 1 0 Heme NO binding associated Exonuc_VII_L PF02601.15 KDO33137.1 - 6.1 6.3 12.3 2.2 7.8 7.7 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_17 PF13207.6 KDO33137.1 - 7.5 7.0 6.6 25 5.3 0.0 3.9 4 0 0 4 4 3 0 AAA domain DHC_N1 PF08385.12 KDO33138.1 - 3e-151 504.9 0.1 3.8e-151 504.5 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Sec8_exocyst PF04048.14 KDO33138.1 - 0.15 12.0 0.8 0.36 10.7 0.3 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain WD40 PF00400.32 KDO33140.1 - 1.2e-18 67.1 11.5 3.4e-08 34.0 0.0 5.8 6 2 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO33140.1 - 1.9e-05 24.9 0.2 0.0088 16.3 0.0 3.5 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KDO33140.1 - 0.065 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain EF-hand_7 PF13499.6 KDO33141.1 - 8.4e-08 32.6 0.1 1.9e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO33141.1 - 9e-07 28.3 0.0 0.082 12.9 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KDO33141.1 - 7.5e-05 22.0 0.0 0.055 13.0 0.0 3.0 2 1 1 3 3 3 2 EF hand EF-hand_10 PF14788.6 KDO33141.1 - 9.8e-05 22.1 0.2 0.022 14.6 0.0 2.9 1 1 2 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO33141.1 - 0.00018 21.3 0.0 0.00042 20.1 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain pair RIIa PF02197.17 KDO33141.1 - 0.012 15.2 0.0 0.21 11.3 0.0 2.4 3 0 0 3 3 3 0 Regulatory subunit of type II PKA R-subunit PPR PF01535.20 KDO33142.1 - 2.5e-06 27.3 0.1 0.11 12.8 0.0 4.8 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 KDO33142.1 - 0.0001 22.4 0.0 0.068 13.4 0.0 4.5 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 KDO33142.1 - 0.023 14.8 0.0 58 3.9 0.0 4.8 6 0 0 6 6 6 0 Pentatricopeptide repeat domain Ras PF00071.22 KDO33143.1 - 9.3e-50 168.4 0.2 1.1e-49 168.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO33143.1 - 1.1e-34 119.2 0.4 1.7e-34 118.6 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO33143.1 - 4.6e-16 58.7 0.1 7e-16 58.2 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO33143.1 - 2.4e-07 30.3 0.0 2.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KDO33143.1 - 4.2e-06 26.8 0.1 6.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KDO33143.1 - 6.1e-06 25.9 1.7 0.00083 18.9 0.1 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KDO33143.1 - 6.5e-06 25.7 0.1 7.7e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Raptor_N PF14538.6 KDO33143.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF4265 PF14085.6 KDO33143.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Peptidase_M14 PF00246.24 KDO33144.1 - 6e-15 55.8 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KDO33144.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Kinesin PF00225.23 KDO33145.1 - 2e-97 326.1 0.5 3e-97 325.5 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO33145.1 - 1.4e-23 83.4 0.0 6e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding PhoH PF02562.16 KDO33145.1 - 0.0015 18.0 0.1 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Upf2 PF04050.14 KDO33145.1 - 0.0068 17.1 1.4 0.017 15.8 1.4 1.6 1 0 0 1 1 1 1 Up-frameshift suppressor 2 DUF4763 PF15960.5 KDO33145.1 - 0.017 14.4 0.7 0.36 10.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) AAA_30 PF13604.6 KDO33145.1 - 0.029 14.1 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 KDO33145.1 - 0.061 13.3 1.1 0.61 10.1 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit tRNA_U5-meth_tr PF05958.11 KDO33146.1 - 2.9e-16 59.4 0.0 8.9e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KDO33146.1 - 8.5e-08 32.8 0.3 3.6e-07 30.8 0.1 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33146.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO33146.1 - 5.7e-06 26.0 0.1 1.1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KDO33146.1 - 0.00017 21.2 0.1 0.00035 20.2 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KDO33146.1 - 0.00031 20.5 0.1 0.00057 19.7 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KDO33146.1 - 0.00058 19.5 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KDO33146.1 - 0.0029 17.1 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO33146.1 - 0.0045 17.6 0.0 0.016 15.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33146.1 - 0.012 16.4 0.0 0.03 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KDO33146.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 KDO33146.1 - 0.084 12.5 0.1 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 UPF0061 PF02696.14 KDO33147.1 - 8.2e-107 357.9 0.0 2.6e-106 356.2 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TetR_C_36 PF18598.1 KDO33147.1 - 0.096 12.7 0.1 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lactonase PF10282.9 KDO33148.1 - 2.4e-49 168.4 0.7 5.6e-41 140.9 0.1 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KDO33148.1 - 0.00087 18.9 0.0 0.36 10.4 0.0 2.4 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KDO33148.1 - 0.013 15.7 0.2 1.3 9.3 0.0 3.5 4 0 0 4 4 4 0 Arylesterase NHL PF01436.21 KDO33148.1 - 0.089 12.9 1.7 12 6.2 0.1 4.1 5 0 0 5 5 5 0 NHL repeat Lactonase PF10282.9 KDO33149.1 - 2.5e-73 247.3 1.7 3.1e-73 247.0 1.7 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KDO33149.1 - 3.8e-07 29.9 0.4 0.16 11.6 0.0 4.0 1 1 3 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region PhoLip_ATPase_N PF16209.5 KDO33150.1 - 3.1e-26 90.8 3.1 5.6e-26 90.0 3.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KDO33150.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Guanylate_cyc PF00211.20 KDO33151.1 - 2.5e-90 301.0 1.2 3.9e-47 160.2 0.5 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 KDO33151.1 - 1e-65 222.0 24.5 1e-65 222.0 24.5 3.6 3 1 1 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KDO33151.1 - 4.7e-09 36.8 0.0 3.1e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO33151.1 - 6.5e-08 32.6 0.0 5e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KDO33151.1 - 0.012 15.4 0.1 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HNOBA PF07701.14 KDO33151.1 - 0.45 9.9 2.1 5.3 6.4 0.3 2.3 2 0 0 2 2 2 0 Heme NO binding associated CBF PF03914.17 KDO33152.1 - 1.8e-55 187.6 2.3 6.3e-55 185.8 0.2 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 KDO33152.1 - 0.003 16.2 0.5 0.016 13.8 0.2 2.0 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KDO33152.1 - 0.007 16.4 1.4 0.013 15.6 0.5 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 NOC3p PF07540.11 KDO33152.1 - 0.043 14.3 0.1 0.58 10.6 0.0 2.7 2 0 0 2 2 2 0 Nucleolar complex-associated protein RasGEF_N_2 PF14663.6 KDO33152.1 - 0.12 12.8 0.4 0.48 10.8 0.1 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 KDO33152.1 - 0.2 11.7 0.8 0.58 10.3 0.8 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein GAIN_A PF18619.1 KDO33152.1 - 0.52 10.6 9.8 2.2 8.5 0.5 3.5 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF913 PF06025.12 KDO33152.1 - 1.6 7.6 17.1 0.18 10.7 0.4 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) PTA_PTB PF01515.19 KDO33153.1 - 6.4e-113 377.3 1.8 8.9e-113 376.8 1.8 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 KDO33153.1 - 1.2e-19 71.0 0.1 3e-19 69.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 KDO33153.1 - 5.2e-15 55.1 0.3 2e-14 53.3 0.0 2.2 3 0 0 3 3 3 1 DRTGG domain CheW PF01584.19 KDO33153.1 - 0.12 12.0 0.0 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 CheW-like domain Acetate_kinase PF00871.17 KDO33154.1 - 2.2e-138 461.2 0.0 2.6e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family PTA_PTB PF01515.19 KDO33155.1 - 8e-112 373.7 2.2 1.1e-111 373.2 2.2 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 KDO33155.1 - 8.5e-22 77.9 0.1 4.8e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DRTGG PF07085.12 KDO33155.1 - 4.2e-15 55.4 1.1 1.1e-14 54.1 0.1 2.3 3 0 0 3 3 3 1 DRTGG domain Ykof PF07615.11 KDO33155.1 - 0.25 11.8 0.8 3.1 8.3 0.0 2.9 3 0 0 3 3 3 0 YKOF-related Family Chitin_synth_1 PF01644.17 KDO33156.1 - 2.5e-46 157.6 0.0 4.1e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KDO33156.1 - 1.1e-22 80.3 0.8 3.2e-22 78.9 0.4 1.9 2 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KDO33156.1 - 4.1e-12 46.4 3.4 4.1e-12 46.4 3.4 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KDO33156.1 - 8.4e-05 22.6 0.0 0.00039 20.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 KDO33156.1 - 0.00075 19.4 0.1 0.0024 17.8 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal MIT PF04212.18 KDO33156.1 - 0.0032 17.5 0.1 0.0082 16.2 0.1 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain NCD1 PF04904.13 KDO33156.1 - 0.1 12.6 0.1 4 7.5 0.0 2.5 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Glyco_hydro_1 PF00232.18 KDO33157.1 - 4.9e-164 546.1 0.0 5.5e-164 545.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 KDO33158.1 - 3.8e-148 493.7 1.3 1.6e-145 485.0 1.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 KDO33159.1 - 2.3e-158 527.3 0.1 2.7e-158 527.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AAA_33 PF13671.6 KDO33160.1 - 1.1e-21 77.5 0.0 3.1e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KDO33160.1 - 9.2e-12 44.7 0.0 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 KDO33160.1 - 2.5e-06 27.1 0.0 6.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 KDO33160.1 - 9.3e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KDO33160.1 - 3.1e-05 24.5 0.0 8.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KDO33160.1 - 0.00028 21.3 0.0 0.00082 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KDO33160.1 - 0.042 14.3 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KDO33160.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KDO33160.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 KDO33160.1 - 0.54 11.0 4.0 7.2 7.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 KDO33161.1 - 1.3e-23 83.8 2.3 5e-22 78.6 2.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KDO33161.1 - 1e-05 25.5 0.0 4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Zn_ribbon_recom PF13408.6 KDO33161.1 - 0.062 13.8 0.9 0.14 12.7 0.9 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SSF PF00474.17 KDO33162.1 - 6.2e-10 38.5 34.1 2.5e-08 33.2 34.1 3.0 1 1 0 1 1 1 1 Sodium:solute symporter family NmrA PF05368.13 KDO33163.1 - 7.8e-05 22.3 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KDO33163.1 - 0.012 15.5 1.8 0.048 13.5 1.0 2.4 1 1 1 2 2 2 0 NAD(P)H-binding F420_oxidored PF03807.17 KDO33164.1 - 1.6e-09 38.2 0.0 2.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KDO33164.1 - 6.6e-05 22.8 0.4 0.00012 21.9 0.4 1.4 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 KDO33164.1 - 0.00062 19.2 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KDO33164.1 - 0.091 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KDO33164.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 KDO33164.1 - 0.11 13.4 0.0 0.29 12.0 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 KDO33164.1 - 0.11 12.4 0.9 0.59 10.1 0.9 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tub PF01167.18 KDO33165.1 - 1.7e-50 172.0 0.0 3.8e-50 170.9 0.0 1.6 1 1 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 KDO33165.1 - 6.4e-08 32.8 11.8 6.4e-08 32.8 11.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO33165.1 - 4.6e-07 29.6 10.9 4.6e-07 29.6 10.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO33165.1 - 1.2e-05 25.0 9.4 1.2e-05 25.0 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO33165.1 - 0.00018 21.3 11.9 0.00018 21.3 11.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO33165.1 - 0.00052 20.0 4.8 0.00056 19.9 3.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO33165.1 - 0.001 18.9 8.5 0.001 18.9 8.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KDO33165.1 - 0.0018 18.5 10.0 0.0018 18.5 10.0 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 KDO33165.1 - 0.006 16.5 2.7 0.015 15.3 2.7 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ACC PF17848.1 KDO33165.1 - 0.0065 16.5 0.6 0.0065 16.5 0.6 1.9 2 0 0 2 2 1 1 Acetyl-coA carboxylase zinc finger domain zf-ANAPC11 PF12861.7 KDO33165.1 - 0.045 13.8 2.6 0.091 12.8 2.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KDO33165.1 - 0.25 11.2 4.6 0.63 10.0 4.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 KDO33165.1 - 0.68 10.1 16.0 3.2 7.9 16.0 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 KDO33165.1 - 1.7 8.8 9.1 2.1 8.5 7.9 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 Tub PF01167.18 KDO33166.1 - 1.4e-24 87.2 0.0 2.2e-23 83.3 0.0 2.0 1 1 1 2 2 2 2 Tub family CRAL_TRIO PF00650.20 KDO33167.1 - 1.3e-28 99.8 0.3 2e-28 99.1 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain FYVE PF01363.21 KDO33167.1 - 7.3e-12 45.3 6.7 1.6e-11 44.1 6.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger CNOT11 PF10155.9 KDO33168.1 - 2.9e-55 185.8 7.5 2.9e-55 185.8 7.5 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 NUDIX PF00293.28 KDO33169.1 - 4.1e-17 62.5 0.0 5.4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3659 PF12396.8 KDO33169.1 - 0.0099 15.8 0.3 0.019 14.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) zf-C3HC4_2 PF13923.6 KDO33170.1 - 2.8e-11 43.0 9.2 4e-11 42.6 9.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO33170.1 - 3.1e-10 39.8 5.3 4.3e-10 39.3 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO33170.1 - 9.1e-10 38.7 10.3 1.2e-09 38.3 10.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KDO33170.1 - 1.3e-09 37.7 9.0 1.8e-09 37.3 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO33170.1 - 1.4e-07 31.4 7.1 2.1e-07 30.8 4.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO33170.1 - 1.8e-07 31.0 6.7 2.5e-07 30.5 6.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO33170.1 - 6.9e-07 29.0 7.0 1e-06 28.5 7.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KDO33170.1 - 3.1e-05 24.0 9.4 5.5e-05 23.2 9.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KDO33170.1 - 0.0058 16.9 10.8 0.012 15.8 10.8 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KDO33170.1 - 0.0076 16.0 2.9 0.013 15.4 2.9 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KDO33170.1 - 0.05 13.3 5.4 0.07 12.9 2.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-NOSIP PF15906.5 KDO33170.1 - 0.06 13.5 0.2 0.087 13.0 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Baculo_IE-1 PF05290.11 KDO33170.1 - 0.11 12.4 4.8 0.18 11.8 4.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KDO33170.1 - 0.2 11.0 1.8 0.31 10.4 1.1 1.6 2 1 0 2 2 2 0 Rtf2 RING-finger Ank_4 PF13637.6 KDO33171.1 - 3.1e-50 167.9 6.2 1.4e-10 41.5 0.0 4.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO33171.1 - 1.2e-47 160.4 16.6 1.4e-14 54.4 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33171.1 - 2.3e-29 101.1 17.2 6e-08 32.8 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO33171.1 - 3.6e-29 99.9 9.1 8.7e-06 26.0 0.4 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KDO33171.1 - 1.5e-27 92.5 4.2 0.011 16.1 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat DUF1843 PF08898.10 KDO33171.1 - 0.16 12.5 3.0 1.4 9.5 0.1 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) Pkinase PF00069.25 KDO33172.1 - 1.7e-66 224.3 0.0 2.4e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33172.1 - 7.1e-34 117.3 0.0 1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KDO33172.1 - 2.9e-16 59.4 0.2 8.1e-16 58.0 0.2 1.8 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 KDO33172.1 - 5.8e-06 25.8 0.0 1.6e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KDO33172.1 - 0.036 13.7 0.0 2.2 7.9 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 K-box PF01486.17 KDO33173.1 - 0.00016 21.8 0.3 0.00024 21.2 0.3 1.2 1 0 0 1 1 1 1 K-box region Peptidase_S9_N PF02897.15 KDO33174.1 - 8.9e-107 357.4 0.0 1.2e-106 357.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KDO33174.1 - 9.4e-61 205.0 0.1 1.4e-60 204.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KDO33174.1 - 0.084 12.1 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RRM_5 PF13893.6 KDO33175.1 - 6.2e-35 119.5 0.0 4.2e-21 74.8 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KDO33175.1 - 4.5e-23 80.8 0.0 4.4e-06 26.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KDO33175.1 - 1.5e-11 44.3 0.0 1.6e-10 41.0 0.0 2.6 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KDO33175.1 - 0.0052 16.6 0.2 1.1 9.1 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif Mur_ligase_M PF08245.12 KDO33176.1 - 0.0005 20.1 0.5 0.0043 17.1 0.1 2.5 1 1 1 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KDO33176.1 - 0.0036 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain HGD-D PF06050.13 KDO33176.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Ank_2 PF12796.7 KDO33177.1 - 1.1e-29 102.8 18.4 1.3e-05 25.6 2.0 7.3 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33177.1 - 6.6e-17 61.7 24.4 0.0028 18.2 0.4 10.6 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33177.1 - 4.3e-10 39.7 27.2 0.45 10.9 0.0 12.0 8 3 6 14 14 14 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33177.1 - 9.8e-10 37.9 15.6 18 6.3 0.0 13.2 13 2 2 15 15 15 1 Ankyrin repeat DUF5049 PF16468.5 KDO33177.1 - 0.0048 16.8 0.0 62 3.6 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5049) Ank PF00023.30 KDO33177.1 - 0.68 10.5 19.0 16 6.2 0.0 8.6 8 3 2 10 10 10 0 Ankyrin repeat ECSCR PF15820.5 KDO33178.1 - 0.022 14.6 0.3 0.079 12.8 0.0 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Serglycin PF04360.12 KDO33178.1 - 0.054 13.4 3.0 1 9.3 1.2 2.6 2 0 0 2 2 2 0 Serglycin DUF2561 PF10812.8 KDO33178.1 - 0.11 12.5 1.1 0.22 11.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) EphA2_TM PF14575.6 KDO33178.1 - 4.6 8.2 5.9 55 4.7 5.9 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KDO33180.1 - 0.017 15.1 0.1 0.017 15.1 0.1 3.3 1 1 3 4 4 4 0 TMEM154 protein family CEND1 PF15677.5 KDO33181.1 - 0.0011 19.6 2.0 0.0011 19.6 2.0 2.0 2 1 0 2 2 2 1 Cell cycle exit and neuronal differentiation protein 1 TMEM154 PF15102.6 KDO33181.1 - 0.002 18.1 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family ODV-E18 PF10717.9 KDO33181.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.9 4 0 0 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 Podoplanin PF05808.11 KDO33181.1 - 0.12 12.5 0.7 0.19 11.9 0.7 1.2 1 0 0 1 1 1 0 Podoplanin AAA_16 PF13191.6 KDO33182.1 - 4.4e-07 30.4 0.2 1.4e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SH2 PF00017.24 KDO33182.1 - 3.6e-06 27.0 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 SH2 domain NACHT PF05729.12 KDO33182.1 - 8.4e-06 25.8 0.5 5.4e-05 23.2 0.1 2.5 2 1 0 2 2 2 1 NACHT domain PhoH PF02562.16 KDO33182.1 - 0.0049 16.4 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein KAP_NTPase PF07693.14 KDO33182.1 - 0.0071 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 KDO33182.1 - 0.0093 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KDO33182.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO33182.1 - 0.047 14.2 0.2 0.25 11.9 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF2264 PF10022.9 KDO33182.1 - 0.13 11.4 0.0 0.49 9.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2264) AAA_30 PF13604.6 KDO33182.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO33182.1 - 0.16 12.3 0.0 0.95 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KDO33182.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FGE-sulfatase PF03781.16 KDO33183.1 - 2.8e-23 82.8 0.1 5.7e-23 81.8 0.1 1.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 bZIP_2 PF07716.15 KDO33184.1 - 0.0023 18.0 5.2 0.0044 17.1 5.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper SnoaL_2 PF12680.7 KDO33184.1 - 0.0041 17.7 0.0 0.023 15.3 0.0 2.1 2 1 1 3 3 3 1 SnoaL-like domain SnoaL PF07366.12 KDO33184.1 - 0.0076 16.0 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF1884 PF08967.10 KDO33184.1 - 0.043 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) UQ_con PF00179.26 KDO33184.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme NUC PF18510.1 KDO33185.1 - 0.045 14.2 0.5 0.082 13.3 0.3 1.5 2 0 0 2 2 2 0 Nuclease domain DUF4440 PF14534.6 KDO33185.1 - 0.12 12.8 0.1 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) SGT1 PF07093.11 KDO33187.1 - 2.4e-88 297.1 14.5 3.4e-68 230.6 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein FidL_like PF15941.5 KDO33187.1 - 0.1 13.1 2.4 8 7.0 1.7 2.6 2 0 0 2 2 2 0 FidL-like putative membrane protein SGS PF05002.15 KDO33187.1 - 8.1 6.6 7.0 1.9 8.7 2.9 2.0 2 0 0 2 2 2 0 SGS domain NOA36 PF06524.12 KDO33187.1 - 8.7 5.6 6.7 13 5.0 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_4 PF13637.6 KDO33188.1 - 3.4e-18 65.7 9.5 1.8e-05 25.2 0.1 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO33188.1 - 4.6e-17 62.4 7.5 2.2e-09 37.8 0.3 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33188.1 - 5.1e-11 42.6 12.6 0.025 14.9 0.0 6.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33188.1 - 9e-07 28.7 10.0 4.8 8.1 0.1 6.4 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.30 KDO33188.1 - 0.58 10.7 9.0 31 5.2 0.0 5.2 2 1 1 3 3 3 0 Ankyrin repeat TPR_12 PF13424.6 KDO33189.1 - 0.0001 22.5 0.9 0.0001 22.5 0.9 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat BBE PF08031.12 KDO33189.1 - 0.096 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Berberine and berberine like Lactonase PF10282.9 KDO33190.1 - 3e-70 237.2 0.7 3.5e-70 237.0 0.7 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KDO33190.1 - 4.6e-05 23.1 0.2 0.94 9.0 0.0 3.6 3 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KDO33190.1 - 7.2e-05 22.6 3.1 0.24 11.5 0.2 3.8 4 0 0 4 4 4 2 NHL repeat zf-TRAF_2 PF15965.5 KDO33191.1 - 0.00051 20.5 2.0 0.38 11.2 0.1 2.3 2 0 0 2 2 2 2 TRAF-like zinc-finger PAP_assoc PF03828.19 KDO33191.1 - 0.0012 19.0 0.1 0.023 14.9 0.1 2.5 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KDO33191.1 - 0.0028 17.9 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-TRAF PF02176.18 KDO33191.1 - 0.099 13.4 4.5 2.4 8.9 0.6 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger GFO_IDH_MocA PF01408.22 KDO33193.1 - 1.5e-26 93.6 0.5 2.8e-26 92.7 0.5 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KDO33193.1 - 1.3e-07 31.6 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.20 KDO33193.1 - 2.5e-05 24.4 0.1 5.2e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KDO33193.1 - 3.8e-05 24.2 0.0 9.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 KDO33193.1 - 0.00026 21.6 0.3 0.00044 20.9 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KDO33193.1 - 0.0005 19.5 0.0 0.00089 18.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KDO33193.1 - 0.0017 18.6 0.5 0.0065 16.7 0.1 2.0 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Rossmann-like PF10727.9 KDO33193.1 - 0.0026 17.6 0.1 0.0053 16.6 0.1 1.6 1 0 0 1 1 1 1 Rossmann-like domain ThiF PF00899.21 KDO33193.1 - 0.021 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.6 KDO33193.1 - 0.023 15.2 0.4 0.066 13.7 0.4 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain Gp_dh_N PF00044.24 KDO33193.1 - 0.033 14.5 0.1 0.082 13.3 0.1 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SBBP PF06739.11 KDO33194.1 - 0.00017 21.5 3.2 1.8 8.6 0.0 4.0 3 0 0 3 3 3 2 Beta-propeller repeat PQQ_3 PF13570.6 KDO33194.1 - 0.035 14.6 14.6 0.29 11.7 0.1 5.1 4 2 0 4 4 4 0 PQQ-like domain Mito_carr PF00153.27 KDO33195.1 - 5.3e-59 196.1 1.8 2.8e-20 72.0 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KDO33195.1 - 0.11 12.8 2.6 2.6 8.5 0.0 3.0 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family ACD PF16671.5 KDO33196.1 - 0.095 11.0 0.3 0.14 10.5 0.3 1.1 1 0 0 1 1 1 0 Actin cross-linking domain FYVE PF01363.21 KDO33197.1 - 1.3e-13 50.8 13.7 2.5e-13 49.9 13.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO33197.1 - 0.052 13.8 5.8 0.1 12.8 5.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger NOB1_Zn_bind PF08772.11 KDO33197.1 - 0.62 10.3 9.3 1.4 9.2 9.3 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PhoLip_ATPase_C PF16212.5 KDO33198.1 - 1.7e-72 244.2 25.6 1.7e-72 244.2 25.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO33198.1 - 9.3e-22 76.5 0.6 9.3e-22 76.5 0.6 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO33198.1 - 7.6e-11 42.7 1.3 2.6e-05 24.6 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO33198.1 - 9.4e-11 41.7 0.0 3.3e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO33198.1 - 1.6e-06 27.7 0.3 0.00017 21.1 0.0 3.0 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO33198.1 - 0.0013 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LysE PF01810.18 KDO33199.1 - 0.0068 15.9 1.3 0.02 14.4 1.3 1.7 1 1 0 1 1 1 1 LysE type translocator DUF996 PF06195.13 KDO33199.1 - 0.032 14.5 0.1 0.045 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF996) TRIQK PF15168.6 KDO33199.1 - 6 6.8 6.1 2.8 7.9 1.4 2.1 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF4586 PF15239.6 KDO33201.1 - 7e-57 193.9 9.9 7.9e-57 193.7 9.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) MIOX PF05153.15 KDO33202.1 - 1.2e-97 326.4 0.6 1.5e-97 326.0 0.6 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KDO33202.1 - 0.05 13.8 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 HD domain Sdh5 PF03937.16 KDO33202.1 - 0.084 12.8 0.3 0.22 11.5 0.3 1.7 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase LSM PF01423.22 KDO33203.1 - 1.7e-15 56.4 0.3 2.1e-15 56.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KDO33203.1 - 0.0017 18.5 0.2 0.0021 18.1 0.2 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 KDO33203.1 - 0.061 13.5 0.2 0.094 12.9 0.2 1.3 1 1 0 1 1 1 0 RimP C-terminal SH3 domain ETF_QO PF05187.13 KDO33203.1 - 0.15 12.2 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Bacteriocin_IIc PF10439.9 KDO33204.1 - 3.6 7.8 8.7 3.7 7.8 7.3 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide SMN PF06003.12 KDO33205.1 - 2.5e-05 23.7 0.7 6.8e-05 22.3 0.4 1.7 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KDO33205.1 - 0.0002 21.3 0.0 0.0015 18.5 0.0 2.1 1 1 1 2 2 2 1 Tudor domain DPBB_1 PF03330.18 KDO33206.1 - 1.1e-05 25.6 0.1 4.2e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Lytic transglycolase DUF4366 PF14283.6 KDO33207.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SOG2 PF10428.9 KDO33207.1 - 2.6 7.1 13.9 2.7 7.1 13.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein PRMT5 PF05185.16 KDO33208.1 - 6.5e-66 221.4 0.0 9e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KDO33208.1 - 1.9e-65 220.6 0.0 2.7e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Methyltransf_31 PF13847.6 KDO33208.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GDNF PF02351.16 KDO33208.1 - 1.8 9.6 11.7 49 5.0 8.2 2.7 2 0 0 2 2 2 0 GDNF/GAS1 domain Bromo_TP PF07524.13 KDO33209.1 - 3.6e-13 49.3 0.2 1e-12 47.9 0.1 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 KDO33209.1 - 1.9e-09 37.9 2.0 1.9e-09 37.9 2.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term CENP-T_C PF15511.6 KDO33209.1 - 0.027 14.6 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KDO33209.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit OB_NTP_bind PF07717.16 KDO33210.1 - 3.2e-19 69.1 0.0 9e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KDO33210.1 - 1.1e-16 61.0 1.1 1.1e-15 57.8 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KDO33210.1 - 1.9e-13 50.7 0.0 5.3e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO33210.1 - 5.8e-09 36.0 0.1 1.3e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 KDO33210.1 - 1.4e-05 25.3 0.0 4.3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 RWD domain AAA_19 PF13245.6 KDO33210.1 - 3.5e-05 24.2 0.0 8.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO33210.1 - 0.00047 19.3 0.9 0.0086 15.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein dsrm PF00035.26 KDO33210.1 - 0.00084 20.0 0.3 0.0024 18.6 0.0 2.0 2 0 0 2 2 1 1 Double-stranded RNA binding motif ResIII PF04851.15 KDO33210.1 - 0.0051 16.8 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KDO33210.1 - 0.019 15.0 0.0 0.094 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KDO33210.1 - 0.02 14.8 0.4 0.083 12.8 0.4 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 KDO33210.1 - 0.04 13.3 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KDO33210.1 - 0.044 14.1 3.8 0.18 12.0 0.8 3.2 2 1 0 2 2 2 0 AAA domain DND1_DSRM PF14709.7 KDO33210.1 - 0.061 13.6 0.1 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.6 KDO33210.1 - 0.065 13.0 0.1 8.2 6.2 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KDO33210.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 KDO33210.1 - 0.16 11.6 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 KDO33210.1 - 0.16 11.7 5.1 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO33210.1 - 2.8 8.4 4.8 1.3 9.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.6 KDO33210.1 - 8.7 6.7 10.9 1 9.8 0.1 3.9 4 1 0 4 4 4 0 AAA ATPase domain KDZ PF18758.1 KDO33211.1 - 4.3e-13 49.4 0.4 1.2e-07 31.6 0.1 3.0 1 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase DUF3045 PF11243.8 KDO33211.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Peptidase_M3 PF01432.20 KDO33213.1 - 9.8e-116 387.7 0.3 1.3e-115 387.3 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M3 Chitin_synth_1N PF08407.11 KDO33213.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Chitin synthase N-terminal YopE PF03545.13 KDO33214.1 - 0.068 13.4 0.1 0.082 13.1 0.1 1.1 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) TPD PF14811.6 KDO33214.1 - 0.22 11.4 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Peptidase_M3 PF01432.20 KDO33215.1 - 6.1e-119 398.3 0.1 8.3e-119 397.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KDO33215.1 - 0.047 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Chitin_synth_1N PF08407.11 KDO33215.1 - 0.092 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Chitin synthase N-terminal FYVE PF01363.21 KDO33216.1 - 0.00046 20.3 4.6 0.00046 20.3 4.6 2.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KDO33216.1 - 0.014 15.6 3.7 0.05 13.8 3.7 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger TFIIF_alpha PF05793.12 KDO33216.1 - 0.023 13.3 8.0 0.036 12.7 8.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGL PF08450.12 KDO33217.1 - 1.2e-11 44.6 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KDO33217.1 - 1.3e-05 25.0 0.0 0.13 12.3 0.0 4.2 4 0 0 4 4 4 2 NHL repeat SKG6 PF08693.10 KDO33217.1 - 0.036 13.5 1.7 0.091 12.2 1.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SBBP PF06739.11 KDO33217.1 - 0.35 10.9 5.2 0.61 10.1 0.0 3.6 4 0 0 4 4 4 0 Beta-propeller repeat IQ PF00612.27 KDO33218.1 - 3.9e-05 23.1 0.5 3.9e-05 23.1 0.5 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif PHD_2 PF13831.6 KDO33218.1 - 0.0011 18.5 3.8 0.02 14.4 0.3 2.5 2 0 0 2 2 2 1 PHD-finger PH_13 PF16652.5 KDO33218.1 - 0.0078 16.0 0.2 0.089 12.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1677 PF07911.13 KDO33218.1 - 0.019 15.3 0.5 0.055 13.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) PH PF00169.29 KDO33218.1 - 0.024 15.1 0.2 0.081 13.4 0.1 1.9 2 0 0 2 2 2 0 PH domain PyrI_C PF02748.15 KDO33218.1 - 0.027 14.4 0.2 0.077 12.9 0.2 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zf_RING PF16744.5 KDO33218.1 - 0.063 13.4 1.5 0.17 12.0 1.5 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 KDO33218.1 - 0.25 11.4 4.1 0.34 11.0 2.2 2.1 1 1 1 2 2 2 0 PHD-finger PHD PF00628.29 KDO33218.1 - 0.35 10.8 6.0 2.5 8.1 6.0 2.2 1 1 0 1 1 1 0 PHD-finger GFO_IDH_MocA PF01408.22 KDO33219.1 - 3e-21 76.5 0.5 4.9e-21 75.8 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KDO33219.1 - 0.00064 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KDO33219.1 - 0.0066 16.6 0.1 0.017 15.2 0.1 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KDO33219.1 - 0.012 16.1 0.2 0.03 14.9 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 KDO33219.1 - 0.021 15.2 0.1 0.084 13.2 0.1 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 KDO33219.1 - 0.056 13.5 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain TrkA_N PF02254.18 KDO33219.1 - 0.081 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain zf-C2H2_12 PF18658.1 KDO33220.1 - 0.089 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type DSPn PF14671.6 KDO33221.1 - 4.6e-28 98.4 0.0 1.1e-27 97.2 0.0 1.7 1 1 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KDO33221.1 - 5.2e-10 39.3 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KDO33221.1 - 3.5e-05 24.0 0.0 6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KDO33221.1 - 0.00031 20.4 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KDO33221.1 - 0.006 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KDO33221.1 - 0.032 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family SlyX PF04102.12 KDO33222.1 - 0.047 14.3 13.3 0.11 13.1 1.1 3.0 1 1 2 3 3 3 0 SlyX Sulphotransf PF09037.10 KDO33222.1 - 0.048 13.2 0.9 0.092 12.3 0.9 1.4 1 0 0 1 1 1 0 Stf0 sulphotransferase DOG1 PF14144.6 KDO33222.1 - 0.18 12.0 1.4 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Seed dormancy control APG6_N PF17675.1 KDO33222.1 - 1.5 9.4 12.0 2.8 8.5 11.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 KDO33222.1 - 1.7 9.3 7.2 1.9 9.1 4.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 KDO33222.1 - 4.1 7.6 6.6 2.2 8.4 4.0 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TFIIA PF03153.13 KDO33223.1 - 0.17 11.8 0.9 0.22 11.4 0.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 KDO33224.1 - 4.5 5.9 4.3 6.6 5.4 4.3 1.2 1 0 0 1 1 1 0 Presenilin SLAIN PF15301.6 KDO33226.1 - 0.039 13.2 0.2 0.061 12.6 0.2 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family zf-C2H2 PF00096.26 KDO33227.1 - 0.038 14.4 0.3 0.085 13.3 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Herpes_BLRF2 PF05812.12 KDO33228.1 - 0.023 14.9 0.5 0.048 13.8 0.3 1.7 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein BLOC1_2 PF10046.9 KDO33228.1 - 0.028 14.7 2.5 0.039 14.3 0.4 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPO PF05929.11 KDO33228.1 - 0.06 13.0 1.6 0.075 12.6 1.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 KDO33228.1 - 0.092 11.6 6.1 0.13 11.2 6.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 KDO33228.1 - 0.11 11.0 11.0 0.11 11.0 11.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 KDO33228.1 - 0.17 12.4 0.2 13 6.4 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KDO33228.1 - 0.39 11.4 13.5 0.67 10.6 5.9 3.1 2 2 0 2 2 2 0 SlyX KASH_CCD PF14662.6 KDO33228.1 - 0.42 10.4 6.4 0.14 12.0 1.2 2.0 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Med9 PF07544.13 KDO33228.1 - 2.2 8.4 5.2 0.3 11.2 0.4 2.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PH PF00169.29 KDO33230.1 - 0.00012 22.6 0.0 0.00067 20.1 0.0 2.4 2 0 0 2 2 2 1 PH domain SnoaL_2 PF12680.7 KDO33230.1 - 0.0015 19.2 0.0 0.016 15.9 0.0 2.4 2 0 0 2 2 2 1 SnoaL-like domain Ipi1_N PF12333.8 KDO33230.1 - 0.14 12.7 0.2 0.6 10.7 0.1 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation SAPS PF04499.15 KDO33230.1 - 0.48 9.2 4.0 0.51 9.1 0.1 2.6 2 2 0 2 2 2 0 SIT4 phosphatase-associated protein Clathrin_lg_ch PF01086.17 KDO33231.1 - 0.00066 19.8 0.1 0.00066 19.8 0.1 2.7 3 0 0 3 3 3 1 Clathrin light chain DUF632 PF04782.12 KDO33231.1 - 0.099 11.9 4.2 0.28 10.5 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF632) Mito_carr PF00153.27 KDO33232.1 - 1.5e-29 101.7 1.2 2.6e-14 52.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M28 PF04389.17 KDO33233.1 - 6.5e-11 42.3 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 zf-TRAF PF02176.18 KDO33234.1 - 1e-19 70.9 64.3 0.00022 21.9 2.8 7.3 6 2 1 7 7 7 6 TRAF-type zinc finger Laminin_G_3 PF13385.6 KDO33234.1 - 3.4e-07 30.5 0.0 9.4e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4570 PF15134.6 KDO33234.1 - 0.0098 15.9 3.0 0.79 9.8 0.6 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4570) PGM_PMM_I PF02878.16 KDO33235.1 - 1.2e-33 115.7 0.1 2.6e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KDO33235.1 - 4.7e-21 75.3 0.0 1.6e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KDO33235.1 - 7.9e-17 61.5 0.2 1.7e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KDO33235.1 - 1.3e-07 31.6 0.0 5e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WD40 PF00400.32 KDO33237.1 - 0.0001 23.0 1.4 0.0048 17.7 1.4 2.9 1 1 0 1 1 1 1 WD domain, G-beta repeat BCAS3 PF12490.8 KDO33237.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 Arginase PF00491.21 KDO33238.1 - 4.9e-17 62.3 0.0 6.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family IBN_N PF03810.19 KDO33239.1 - 4.8e-12 45.6 0.3 4.7e-10 39.2 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KDO33239.1 - 3.7e-08 33.5 2.5 1.4e-07 31.7 0.5 3.0 3 0 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.10 KDO33239.1 - 8e-07 28.2 0.0 0.0014 17.6 0.0 3.1 3 0 0 3 3 3 2 Cse1 DUF1041 PF06292.17 KDO33239.1 - 0.14 12.6 0.1 28 5.2 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1041) Mito_carr PF00153.27 KDO33240.1 - 7.5e-56 186.1 4.1 6.6e-19 67.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO33240.1 - 0.11 11.6 1.2 5.6 6.0 0.0 2.8 3 0 0 3 3 3 0 Gammaproteobacterial serine protease SWIM PF04434.17 KDO33241.1 - 3.9e-10 39.2 0.4 7.6e-10 38.3 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 KDO33241.1 - 0.00068 20.0 0.0 0.0024 18.2 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 KDO33241.1 - 0.0043 17.0 0.5 0.0085 16.1 0.5 1.4 1 0 0 1 1 1 1 MuDR family transposase FAR1 PF03101.15 KDO33241.1 - 0.081 13.6 0.5 0.3 11.8 0.5 1.9 1 1 0 1 1 1 0 FAR1 DNA-binding domain Phage_attach PF05354.11 KDO33242.1 - 3.9e-05 23.5 0.1 14 5.6 0.0 5.2 6 1 1 7 7 7 3 Phage Head-Tail Attachment PTSIIA_gutA PF03829.13 KDO33242.1 - 0.0003 20.6 0.0 39 4.2 0.0 6.1 7 0 0 7 7 7 1 PTS system glucitol/sorbitol-specific IIA component S4_2 PF13275.6 KDO33242.1 - 9.9 6.1 7.5 24 4.8 0.1 4.9 8 0 0 8 8 8 0 S4 domain MCM PF00493.23 KDO33243.1 - 1.9e-99 331.3 0.0 6e-99 329.7 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KDO33243.1 - 1.3e-29 102.6 1.1 2.6e-29 101.6 1.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KDO33243.1 - 3e-22 78.9 0.9 6.8e-22 77.7 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KDO33243.1 - 2e-08 33.9 0.1 1.6e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KDO33243.1 - 4.8e-06 27.1 0.1 4.4e-05 24.0 0.0 2.5 2 1 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 KDO33243.1 - 0.00082 19.2 0.1 0.0031 17.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KDO33243.1 - 0.012 15.3 0.1 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KDO33243.1 - 0.015 15.3 0.1 0.26 11.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TBPIP PF07106.13 KDO33243.1 - 0.042 13.8 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Orai-1 PF07856.12 KDO33245.1 - 1.9e-17 63.5 2.3 2.8e-17 62.9 2.3 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Saf_2TM PF18303.1 KDO33245.1 - 0.0059 16.2 5.6 0.04 13.5 0.3 2.2 1 1 1 2 2 2 2 SAVED-fused 2TM effector domain Protocadherin PF08374.11 KDO33245.1 - 0.066 13.2 0.1 0.092 12.7 0.1 1.2 1 0 0 1 1 1 0 Protocadherin UCH_C PF18031.1 KDO33245.1 - 0.069 13.1 2.3 0.22 11.5 2.3 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases DUF4013 PF13197.6 KDO33245.1 - 0.085 12.7 5.6 0.086 12.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Orai-1 PF07856.12 KDO33246.1 - 3.4e-31 108.3 2.3 4.5e-31 107.9 2.3 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity Jiraiya PF15038.6 KDO33246.1 - 0.0034 16.8 5.3 0.0056 16.1 4.7 1.6 1 1 0 1 1 1 1 Jiraiya Exonuc_VII_L PF02601.15 KDO33246.1 - 0.076 12.6 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2157 PF09925.9 KDO33246.1 - 2.9 7.7 7.8 21 4.9 7.8 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Orai-1 PF07856.12 KDO33247.1 - 8.1e-36 123.3 3.1 1.2e-35 122.8 3.1 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Exonuc_VII_L PF02601.15 KDO33247.1 - 0.074 12.6 0.3 0.12 11.9 0.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jiraiya PF15038.6 KDO33247.1 - 0.51 9.8 12.6 13 5.2 12.6 2.5 1 1 0 1 1 1 0 Jiraiya Thioredoxin PF00085.20 KDO33248.1 - 5.6e-13 48.8 0.0 9.3e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KDO33248.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KDO33248.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.11 KDO33248.1 - 0.052 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Ank_2 PF12796.7 KDO33249.1 - 4.3e-17 62.5 0.3 2e-15 57.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33249.1 - 5e-17 61.7 4.2 9.8e-08 32.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO33249.1 - 1.6e-15 57.2 0.5 3.8e-08 33.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO33249.1 - 5.9e-09 36.0 1.2 0.0043 17.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KDO33249.1 - 2.7e-07 30.4 0.1 0.012 16.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF1514 PF07438.11 KDO33249.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) FYVE_2 PF02318.16 KDO33250.1 - 5.4e-06 26.6 5.1 8.8e-06 25.9 5.1 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KDO33250.1 - 0.0026 17.9 9.3 0.0071 16.5 9.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger CEP170_C PF15308.6 KDO33250.1 - 0.081 11.5 5.3 0.11 11.0 5.3 1.1 1 0 0 1 1 1 0 CEP170 C-terminus zf-piccolo PF05715.13 KDO33250.1 - 0.1 12.8 5.7 0.37 11.0 5.7 1.9 1 1 0 1 1 1 0 Piccolo Zn-finger Siva PF05458.12 KDO33250.1 - 3 7.5 11.1 4.9 6.8 11.1 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) C1_2 PF03107.16 KDO33250.1 - 8.1 6.9 8.8 8 6.9 4.8 2.6 1 1 1 2 2 2 0 C1 domain EF-hand_1 PF00036.32 KDO33251.1 - 1.5e-24 83.6 8.1 7.9e-06 25.1 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO33251.1 - 2.5e-22 76.8 9.2 0.00015 21.4 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KDO33251.1 - 6e-21 74.7 7.5 1.5e-12 47.8 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO33251.1 - 1.4e-19 68.6 7.8 1.7e-05 24.1 0.3 4.5 4 0 0 4 4 4 4 EF hand Acyltransferase PF01553.21 KDO33251.1 - 1.5e-15 57.0 0.0 3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EF-hand_8 PF13833.6 KDO33251.1 - 4.4e-15 55.3 10.0 1.7e-06 27.8 0.1 4.8 4 1 1 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO33251.1 - 8.8e-06 26.0 0.1 0.18 12.2 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KDO33251.1 - 0.016 15.1 0.0 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TerB EF-hand_4 PF12763.7 KDO33251.1 - 0.02 14.9 2.3 0.98 9.4 0.3 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Methyltransf_30 PF05430.11 KDO33251.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Adeno_hexon_C PF03678.14 KDO33251.1 - 0.18 11.2 0.0 1.9 7.9 0.0 2.4 3 0 0 3 3 3 0 Hexon, adenovirus major coat protein, C-terminal domain R3H PF01424.22 KDO33252.1 - 3.2e-07 30.2 0.0 5e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 R3H domain R3H-assoc PF13902.6 KDO33252.1 - 2.9e-05 24.5 4.6 5.2e-05 23.6 3.5 1.9 2 0 0 2 2 2 1 R3H-associated N-terminal domain DUF2828 PF11443.8 KDO33253.1 - 3.9e-107 358.9 0.5 1.9e-84 284.0 0.5 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 KDO33253.1 - 0.0015 18.0 0.2 0.0035 16.8 0.2 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 KDO33253.1 - 0.025 15.2 0.1 0.076 13.7 0.1 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF872 PF05915.12 KDO33254.1 - 0.01 16.0 1.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF2070 PF09843.9 KDO33254.1 - 9.7 4.3 15.5 14 3.8 15.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_M3 PF01432.20 KDO33256.1 - 1.8e-100 337.4 0.9 2.8e-78 264.3 0.5 2.3 1 1 1 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.6 KDO33256.1 - 0.04 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like FCD PF07729.12 KDO33256.1 - 0.61 10.5 3.4 2.2 8.7 1.5 2.7 2 1 0 2 2 2 0 FCD domain Peptidase_M3 PF01432.20 KDO33257.1 - 8.8e-117 391.2 0.0 1.1e-116 390.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 UDPGT PF00201.18 KDO33259.1 - 6.3e-12 45.0 0.0 2.6e-11 43.0 0.0 1.9 2 1 1 3 3 3 1 UDP-glucoronosyl and UDP-glucosyl transferase Ank_2 PF12796.7 KDO33260.1 - 2.1e-35 121.1 2.0 7.3e-17 61.7 0.0 5.2 4 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO33260.1 - 1.5e-30 101.8 6.6 0.00042 20.5 0.0 8.7 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KDO33260.1 - 8.6e-30 102.7 4.4 1.5e-05 25.4 0.1 6.7 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33260.1 - 2.1e-26 91.6 9.2 5.3e-07 29.8 0.2 6.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO33260.1 - 4.6e-25 86.9 12.9 0.00027 21.3 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat TIR_2 PF13676.6 KDO33260.1 - 2.3e-23 83.0 0.0 5e-17 62.6 0.0 2.6 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 KDO33260.1 - 0.00051 19.9 0.0 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 KDO33260.1 - 0.034 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) AP_endonuc_2 PF01261.24 KDO33261.1 - 4.7e-34 117.7 0.0 6.2e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NUDIX PF00293.28 KDO33262.1 - 0.00028 20.9 0.0 0.00065 19.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain MRP-L46 PF11788.8 KDO33262.1 - 0.00068 20.4 1.1 0.0027 18.4 0.7 2.3 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Amidohydro_1 PF01979.20 KDO33263.1 - 2.5e-65 221.0 4.1 3.3e-65 220.7 4.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KDO33263.1 - 1.8e-17 64.0 4.6 4.3e-15 56.1 1.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KDO33263.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase PRF PF06875.11 KDO33263.1 - 0.071 12.5 0.2 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Plethodontid receptivity factor PRF Zn_ribbon_SprT PF17283.2 KDO33264.1 - 0.31 11.0 5.2 6.8 6.7 2.2 2.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Mso1_Sec1_bdg PF14475.6 KDO33264.1 - 4.3 7.0 5.5 0.38 10.4 0.3 1.9 3 0 0 3 3 3 0 Sec1-binding region of Mso1 zf-CCHC_4 PF14392.6 KDO33264.1 - 6.2 6.6 13.8 4.5 7.1 1.8 3.4 3 0 0 3 3 3 0 Zinc knuckle Chitin_synth_1 PF01644.17 KDO33265.1 - 1.9e-50 171.1 0.0 3.1e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KDO33265.1 - 9.6e-27 93.8 6.0 7.4e-21 74.4 0.0 3.0 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KDO33265.1 - 8.5e-09 35.6 9.4 8.5e-09 35.6 9.4 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 MIT PF04212.18 KDO33265.1 - 0.0098 15.9 0.8 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 KDO33265.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 KDO33265.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Chitin synthase N-terminal Rad9 PF04139.13 KDO33266.1 - 6.1e-36 124.1 0.0 7.3e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 ATF7IP_BD PF16788.5 KDO33267.1 - 0.16 12.1 0.1 0.48 10.5 0.0 1.7 2 0 0 2 2 2 0 ATF-interacting protein binding domain zf-CW PF07496.15 KDO33269.1 - 6.7e-41 138.1 54.3 8.6e-17 60.9 8.2 5.3 5 0 0 5 5 5 3 CW-type Zinc Finger PHD PF00628.29 KDO33269.1 - 2.3e-07 30.6 55.9 0.00039 20.3 2.3 7.3 6 3 0 6 6 6 4 PHD-finger SR-25 PF10500.9 KDO33269.1 - 8.8e-06 25.5 2.4 8.8e-06 25.5 2.4 3.6 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 KDO33269.1 - 0.0022 18.3 4.6 0.0022 18.3 4.6 3.5 4 1 0 4 4 4 1 AP-3 complex subunit delta-1 zf-HC5HC2H PF13771.6 KDO33269.1 - 1.7 8.9 34.3 0.46 10.8 3.1 5.0 3 1 2 5 5 5 0 PHD-like zinc-binding domain Zf_RING PF16744.5 KDO33269.1 - 3.8 7.7 22.7 0.62 10.2 3.5 4.2 3 1 0 3 3 3 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KDO33269.1 - 5.6 7.4 31.3 4.1 7.8 0.1 4.1 3 0 0 3 3 3 0 Ring finger domain DNA_pol_phi PF04931.13 KDO33271.1 - 0.013 13.7 15.6 0.024 12.8 15.6 1.5 1 0 0 1 1 1 0 DNA polymerase phi UTP15_C PF09384.10 KDO33271.1 - 0.2 11.3 1.9 0.56 9.9 0.1 2.5 2 0 0 2 2 2 0 UTP15 C terminal TFIIA PF03153.13 KDO33271.1 - 0.2 11.6 22.3 0.1 12.6 13.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 KDO33271.1 - 0.72 9.7 12.2 0.17 11.7 8.1 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region p450 PF00067.22 KDO33272.1 - 0.16 10.7 2.0 1.8 7.2 0.4 2.1 1 1 1 2 2 2 0 Cytochrome P450 p450 PF00067.22 KDO33273.1 - 0.57 8.9 3.7 4.7 5.8 0.1 2.3 1 1 1 2 2 2 0 Cytochrome P450 Asp PF00026.23 KDO33274.1 - 4.4e-60 203.7 0.0 8.6e-60 202.8 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO33274.1 - 4.6e-13 49.8 0.4 2.6e-06 27.8 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KDO33274.1 - 0.00032 20.5 0.0 0.00071 19.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KDO33274.1 - 0.00059 20.4 0.1 0.0034 18.0 0.0 2.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KDO33274.1 - 0.032 14.8 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Dicty_CAR PF05462.11 KDO33274.1 - 0.036 13.2 13.6 0.052 12.7 13.6 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor p450 PF00067.22 KDO33275.1 - 0.34 9.6 1.4 6.7 5.3 0.8 2.4 2 1 1 3 3 3 0 Cytochrome P450 Ferric_reduct PF01794.19 KDO33276.1 - 9.2e-17 61.3 9.1 9.2e-17 61.3 9.1 2.5 2 2 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO33276.1 - 2e-12 47.5 0.0 3.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO33276.1 - 5.7e-10 39.3 0.1 1.3e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KDO33276.1 - 0.012 16.2 0.0 0.044 14.4 0.1 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.19 KDO33277.1 - 9.2e-19 67.8 7.9 9.2e-19 67.8 7.9 3.0 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KDO33277.1 - 3.4e-12 46.4 0.0 7.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KDO33277.1 - 3.5e-12 46.7 0.0 6.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KDO33277.1 - 0.06 14.0 0.0 0.18 12.5 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KDO33277.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ferric_reduct PF01794.19 KDO33278.1 - 1.7e-18 66.9 11.1 1.7e-18 66.9 11.1 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KDO33278.1 - 2.6e-12 46.8 0.0 6.2e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KDO33278.1 - 3.2e-05 24.1 0.0 0.0094 16.1 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KDO33279.1 - 1.4e-18 67.2 8.2 1.4e-18 67.2 8.2 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KDO33279.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain Zip PF02535.22 KDO33280.1 - 3.9e-25 88.8 12.4 4.2e-23 82.1 12.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter ThrE PF06738.12 KDO33280.1 - 0.074 12.4 10.4 0.18 11.1 0.6 2.7 3 0 0 3 3 3 0 Putative threonine/serine exporter SpoIIIAC PF06686.11 KDO33280.1 - 0.39 10.9 6.8 0.11 12.7 1.7 2.7 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family DUF2721 PF11026.8 KDO33280.1 - 9.6 6.1 13.7 16 5.4 5.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Ferric_reduct PF01794.19 KDO33281.1 - 4.5e-18 65.6 12.2 4.5e-18 65.6 12.2 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KDO33281.1 - 4.6e-12 46.0 0.1 1.1e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KDO33281.1 - 7e-06 26.2 0.0 0.0027 17.9 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KDO33281.1 - 0.17 12.2 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain zf-CHY PF05495.12 KDO33282.1 - 8.4e-13 48.6 12.7 1.8e-12 47.6 12.7 1.5 1 1 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 KDO33282.1 - 0.0033 17.5 3.1 0.0033 17.5 3.1 2.6 3 0 0 3 3 3 1 Zinc ribbon domain zf_UBZ PF18439.1 KDO33282.1 - 0.031 13.9 7.5 5.5 6.7 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 KDO33282.1 - 0.075 13.0 11.8 0.39 10.7 0.2 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Ecm33 PF12454.8 KDO33282.1 - 0.11 12.7 0.2 0.11 12.7 0.2 1.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein zf-ribbon_3 PF13248.6 KDO33282.1 - 0.25 10.8 0.3 0.25 10.8 0.3 3.4 4 1 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KDO33282.1 - 0.36 10.8 14.0 1.5 8.9 0.7 2.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain CbiX PF01903.17 KDO33283.1 - 3.3e-09 37.0 0.2 1.4e-06 28.6 0.0 2.7 2 0 0 2 2 2 2 CbiX Epimerase PF01370.21 KDO33283.1 - 0.023 14.2 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family EF-hand_1 PF00036.32 KDO33285.1 - 4.4e-23 79.1 13.2 4.4e-06 25.9 2.3 5.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KDO33285.1 - 3.6e-21 75.4 5.6 5e-08 33.3 1.3 5.0 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KDO33285.1 - 1.2e-20 71.6 10.9 4.6e-06 26.1 0.9 6.4 7 0 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.6 KDO33285.1 - 3.7e-18 64.1 10.8 0.00047 19.5 0.1 5.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KDO33285.1 - 4.8e-14 52.0 8.6 1.4e-05 24.9 0.0 5.1 4 2 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KDO33285.1 - 0.018 15.3 0.3 42 4.5 0.0 4.1 3 1 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO33285.1 - 0.042 13.8 1.1 39 4.3 0.0 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 KDO33285.1 - 0.16 12.1 0.0 38 4.4 0.0 3.2 3 0 0 3 3 3 0 p25-alpha Apt1 PF10351.9 KDO33286.1 - 1.7e-05 23.9 0.1 0.14 11.0 0.0 3.3 2 1 1 3 3 3 3 Golgi-body localisation protein domain PWWP PF00855.17 KDO33287.1 - 1.9e-11 44.2 0.1 1.9e-11 44.2 0.1 2.5 3 0 0 3 3 3 1 PWWP domain Med26 PF08711.11 KDO33287.1 - 0.0037 17.2 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Feld-I_B PF09252.10 KDO33287.1 - 0.081 12.9 0.2 0.25 11.3 0.2 1.8 1 0 0 1 1 1 0 Allergen Fel d I-B chain MCM3AP_GANP PF16769.5 KDO33287.1 - 0.18 10.0 5.1 0.24 9.6 5.1 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP MDM31_MDM32 PF08118.11 KDO33287.1 - 1.5 7.4 3.0 2.3 6.8 3.0 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins PDZ_6 PF17820.1 KDO33288.1 - 2.2e-08 33.8 0.1 3.2e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KDO33288.1 - 7.8e-07 29.4 0.1 0.015 15.6 0.0 2.3 2 0 0 2 2 2 2 PDZ domain DUSP PF06337.12 KDO33288.1 - 3.3e-06 27.6 0.0 6.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DUSP domain Methyltransf_16 PF10294.9 KDO33289.1 - 3.8e-23 82.1 0.0 5.1e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO33289.1 - 6.7e-05 22.5 0.0 0.00071 19.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KDO33289.1 - 0.0031 18.2 0.0 0.005 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33289.1 - 0.0054 16.5 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KDO33289.1 - 0.0065 16.4 0.6 0.41 10.6 0.0 2.5 3 0 0 3 3 3 1 KR domain Methyltransf_23 PF13489.6 KDO33289.1 - 0.0069 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33289.1 - 0.016 15.9 0.0 0.046 14.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KDO33289.1 - 0.063 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KDO33289.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) IQ PF00612.27 KDO33290.1 - 1.6e-08 33.6 23.0 0.0048 16.6 0.6 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif Anoctamin PF04547.12 KDO33291.1 - 3.1e-131 438.3 0.1 3.7e-131 438.0 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO33291.1 - 7.2e-14 52.1 0.0 1.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 KDO33291.1 - 0.017 14.4 0.7 0.041 13.2 0.7 1.6 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate DUF2207 PF09972.9 KDO33291.1 - 0.079 11.7 3.0 1.5 7.5 3.0 2.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Anoctamin PF04547.12 KDO33292.1 - 2.1e-71 241.1 0.7 2.6e-71 240.8 0.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KDO33292.1 - 1.1e-14 54.7 0.2 1.9e-14 53.9 0.0 1.5 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 KDO33292.1 - 0.16 11.3 4.7 0.28 10.4 4.7 1.4 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate HXXEE PF13787.6 KDO33292.1 - 0.34 11.7 4.5 1.2 9.9 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF3040 PF11239.8 KDO33292.1 - 4.5 7.6 5.5 0.52 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Anoctamin PF04547.12 KDO33293.1 - 3.5e-47 161.3 0.1 4.1e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel ATPase_2 PF01637.18 KDO33293.1 - 0.071 13.0 0.2 0.079 12.9 0.2 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Glyco_hydro_47 PF01532.20 KDO33295.1 - 1.2e-103 347.5 0.0 1.6e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KDO33295.1 - 1.1e-10 41.4 0.1 2.1e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 PA domain Anoctamin PF04547.12 KDO33296.1 - 5e-118 394.8 0.0 5.8e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3040 PF11239.8 KDO33296.1 - 0.015 15.6 2.4 0.41 10.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 KDO33296.1 - 0.53 9.0 6.6 18 3.9 6.6 2.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) EGF_2 PF07974.13 KDO33297.1 - 0.0015 18.8 32.3 0.0024 18.2 9.1 8.8 8 0 0 8 8 8 2 EGF-like domain EGF_Tenascin PF18720.1 KDO33297.1 - 0.87 9.7 53.8 0.029 14.4 10.8 6.5 4 0 0 4 4 4 0 Tenascin EGF domain Ribonuclease_P PF00825.18 KDO33298.1 - 0.08 13.0 0.0 0.099 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease P Phage_int_SAM_1 PF02899.17 KDO33299.1 - 0.083 13.2 0.2 0.083 13.2 0.2 1.9 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 KDO33300.1 - 5.8e-19 68.5 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33300.1 - 9.9e-08 31.6 0.0 2.4e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KDO33300.1 - 0.86 10.0 5.4 23 5.6 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat Ribosomal_L13 PF00572.18 KDO33301.1 - 4.2e-11 43.2 0.1 3.8e-09 36.9 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Nebulin PF00880.18 KDO33301.1 - 0.22 11.5 2.2 0.38 10.7 2.2 1.4 1 0 0 1 1 1 0 Nebulin repeat TPR_19 PF14559.6 KDO33302.1 - 1.7e-42 143.8 47.2 1.1e-06 29.0 0.2 15.4 11 4 3 15 15 15 9 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33302.1 - 1.8e-37 124.8 23.1 0.0028 18.3 0.1 18.8 14 6 8 22 22 20 8 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33302.1 - 3.2e-30 101.8 53.6 0.0014 18.6 0.0 20.5 23 1 0 23 23 22 8 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33302.1 - 3.8e-29 99.3 41.9 0.0029 17.4 0.0 17.3 19 0 0 19 19 18 6 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33302.1 - 3.1e-28 98.1 17.6 0.0017 19.0 0.3 12.0 11 2 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO33302.1 - 6.1e-23 80.9 41.9 0.0019 18.4 0.0 10.9 9 2 2 11 11 10 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KDO33302.1 - 1.3e-18 67.1 40.8 0.063 13.6 1.7 14.3 10 3 2 13 13 13 6 Tetratricopeptide repeat TPR_9 PF13371.6 KDO33302.1 - 3.6e-15 55.8 12.9 0.0011 19.1 0.1 7.5 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33302.1 - 3.8e-14 51.6 26.1 0.097 12.7 0.1 13.0 13 2 2 15 15 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33302.1 - 2e-11 43.4 20.8 0.00018 21.1 0.0 10.8 9 3 5 14 14 13 3 TPR repeat TPR_8 PF13181.6 KDO33302.1 - 2.7e-11 42.7 47.9 0.08 13.2 0.1 16.0 19 1 1 20 20 15 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33302.1 - 3.2e-10 39.6 22.2 0.38 11.2 0.3 12.4 16 0 0 16 16 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 KDO33302.1 - 2.2e-08 33.6 31.6 4.2e-05 22.9 0.5 9.5 7 4 3 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33302.1 - 1.2e-06 28.7 43.3 0.16 12.7 0.0 15.1 19 0 0 19 19 14 2 Tetratricopeptide repeat ChAPs PF09295.10 KDO33302.1 - 3e-06 26.5 18.9 0.00026 20.1 0.7 5.8 3 2 1 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KDO33302.1 - 1e-05 25.5 11.1 0.2 11.7 0.0 9.0 10 1 1 11 11 10 1 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 KDO33302.1 - 0.00069 19.4 31.8 0.21 11.3 2.9 7.9 6 3 2 8 8 8 2 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 KDO33302.1 - 0.0014 18.3 14.3 0.5 10.0 0.0 6.8 6 2 2 8 8 8 2 Bacterial type III secretion protein (HrpB1_HrpK) YfiO PF13525.6 KDO33302.1 - 0.0022 17.8 8.6 0.41 10.3 0.0 6.1 6 0 0 6 6 6 1 Outer membrane lipoprotein Coatomer_E PF04733.14 KDO33302.1 - 0.0031 17.0 21.3 0.0068 15.9 0.7 6.9 6 3 1 7 7 7 1 Coatomer epsilon subunit TPR_10 PF13374.6 KDO33302.1 - 0.0036 17.1 19.7 4.7 7.2 0.0 9.7 11 0 0 11 11 11 1 Tetratricopeptide repeat DUF4962 PF16332.5 KDO33302.1 - 0.031 12.8 0.5 0.083 11.4 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) MIT PF04212.18 KDO33302.1 - 0.04 14.0 22.5 61 3.8 0.4 9.2 9 0 0 9 9 9 0 MIT (microtubule interacting and transport) domain KTI12 PF08433.10 KDO33302.1 - 0.043 13.2 0.1 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SHNi-TPR PF10516.9 KDO33302.1 - 0.23 11.0 3.6 30 4.2 0.1 4.5 5 0 0 5 5 5 0 SHNi-TPR PknG_TPR PF16918.5 KDO33302.1 - 0.31 9.7 8.7 0.97 8.1 0.0 4.9 5 1 2 7 7 7 0 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 KDO33302.1 - 0.91 9.9 27.6 5.2 7.5 0.3 7.4 9 0 0 9 9 5 0 Tetratricopeptide repeat zf-C2HC_2 PF13913.6 KDO33303.1 - 7.3e-13 48.1 15.1 1.7e-08 34.2 3.5 2.9 3 0 0 3 3 3 2 zinc-finger of a C2HC-type WW PF00397.26 KDO33303.1 - 6.9e-10 38.8 2.0 1.4e-09 37.9 2.0 1.5 1 0 0 1 1 1 1 WW domain zf-CpG_bind_C PF12269.8 KDO33303.1 - 0.069 12.9 0.1 0.069 12.9 0.1 3.8 4 0 0 4 4 4 0 CpG binding protein zinc finger C terminal domain UBZ_FAAP20 PF15750.5 KDO33303.1 - 0.085 12.8 1.4 0.48 10.4 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf_UBZ PF18439.1 KDO33303.1 - 0.18 11.5 4.1 9.3 5.9 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KDO33303.1 - 2.8 7.6 15.3 0.25 11.0 0.2 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) FYVE PF01363.21 KDO33303.1 - 3.4 7.9 8.9 9 6.5 0.5 3.2 3 0 0 3 3 3 0 FYVE zinc finger zf-C2H2 PF00096.26 KDO33303.1 - 7.5 7.2 9.2 88 3.9 0.0 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4630 PF15443.6 KDO33304.1 - 0.2 11.9 0.8 0.33 11.1 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4630) Mito_carr PF00153.27 KDO33305.1 - 3.1e-43 145.6 0.5 1.3e-18 66.7 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.29 KDO33305.1 - 2.2e-38 130.2 0.0 1.1e-21 76.7 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Peptidase_C92 PF05708.12 KDO33305.1 - 8.1e-07 29.3 0.1 0.0009 19.4 0.0 2.7 2 1 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family KIX_2 PF16987.5 KDO33305.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 KIX domain Glycos_transf_4 PF00953.21 KDO33306.1 - 5.9e-37 127.1 7.3 5.9e-37 127.1 7.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF805 PF05656.14 KDO33306.1 - 1.3 9.5 9.5 0.13 12.7 1.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF805) EF-hand_6 PF13405.6 KDO33307.1 - 1.4e-11 43.3 0.1 0.011 15.6 0.2 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KDO33307.1 - 6.2e-10 39.4 0.0 0.00023 21.6 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO33307.1 - 1.5e-08 33.6 0.0 0.021 14.3 0.0 5.2 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KDO33307.1 - 1.2e-05 25.1 0.0 0.021 14.7 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair Type_III_YscG PF09477.10 KDO33307.1 - 0.021 14.9 0.4 9.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Ank_2 PF12796.7 KDO33308.1 - 3.1e-105 344.9 53.0 1.1e-10 41.9 0.0 14.7 2 1 15 17 17 17 17 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33308.1 - 8.4e-75 245.9 49.2 1.3e-07 31.7 0.2 17.5 14 3 2 17 17 17 15 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO33308.1 - 3.6e-73 241.0 26.6 9.9e-08 32.4 0.1 21.2 11 5 13 24 24 24 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33308.1 - 4.4e-65 207.9 29.0 0.002 18.5 0.0 25.4 27 0 0 27 27 27 15 Ankyrin repeat Ank PF00023.30 KDO33308.1 - 2.3e-51 170.1 45.1 0.0001 22.6 0.1 23.9 23 1 2 25 25 25 12 Ankyrin repeat Nitro_FeMo-Co PF02579.17 KDO33308.1 - 0.016 15.5 0.0 48 4.4 0.0 4.8 4 0 0 4 4 4 0 Dinitrogenase iron-molybdenum cofactor CdAMP_rec PF06153.11 KDO33308.1 - 0.27 11.5 1.7 43 4.4 0.0 4.8 4 1 1 5 5 5 0 Cyclic-di-AMP receptor BAT PF15915.5 KDO33308.1 - 0.33 10.8 11.4 1.6 8.6 0.5 5.0 5 0 0 5 5 5 0 GAF and HTH_10 associated domain BTB_2 PF02214.22 KDO33309.1 - 1.6e-09 38.0 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain TPR_1 PF00515.28 KDO33310.1 - 3.7e-50 165.8 35.2 1.5e-07 30.9 0.6 9.6 9 1 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KDO33310.1 - 3.6e-41 138.9 9.3 5e-23 80.8 0.4 3.3 4 0 0 4 4 3 2 STI1 domain TPR_2 PF07719.17 KDO33310.1 - 4e-37 123.3 39.1 3.9e-07 29.7 0.5 9.9 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33310.1 - 9.6e-35 118.0 31.0 2.5e-09 36.7 0.1 8.3 5 2 3 8 8 8 6 TPR repeat TPR_8 PF13181.6 KDO33310.1 - 6.3e-26 88.4 28.4 6.1e-05 22.9 0.1 9.8 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33310.1 - 7.9e-22 76.1 11.2 0.0013 19.4 0.0 8.4 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33310.1 - 4.2e-18 65.7 14.0 1.1e-05 25.9 0.0 6.4 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33310.1 - 3.1e-17 61.3 6.1 0.0075 16.2 0.0 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33310.1 - 1.5e-16 59.5 25.8 0.003 17.8 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33310.1 - 1.5e-15 57.3 22.6 1e-05 25.7 2.3 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33310.1 - 1.8e-11 44.4 16.9 0.00039 20.9 0.6 6.6 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33310.1 - 6.8e-08 32.7 15.4 0.27 11.9 0.1 7.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO33310.1 - 9.6e-07 28.8 5.3 6.5 6.9 0.0 5.8 4 2 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KDO33310.1 - 1.6e-06 28.1 2.2 1.7 8.8 0.2 4.4 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO33310.1 - 0.0018 18.1 25.9 1.1 9.2 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO33310.1 - 0.0088 16.3 2.2 0.0088 16.3 2.2 4.8 3 3 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 DnaI_N PF07319.11 KDO33310.1 - 0.085 13.5 0.0 1.6 9.4 0.0 3.1 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus TPR_20 PF14561.6 KDO33310.1 - 0.15 12.4 8.0 11 6.4 0.1 4.9 4 2 2 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 KDO33310.1 - 0.47 10.6 24.7 7.4 6.7 0.2 7.2 6 2 1 7 7 7 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 KDO33310.1 - 1.3 8.7 11.5 7.3 6.3 0.9 4.7 3 1 3 6 6 5 0 Plant specific mitochondrial import receptor subunit TOM20 CCP_MauG PF03150.14 KDO33310.1 - 3.7 8.2 6.2 36 5.0 2.4 3.4 1 1 0 2 2 2 0 Di-haem cytochrome c peroxidase TPR_3 PF07720.12 KDO33310.1 - 4.8 7.3 16.3 15 5.7 0.7 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 KDO33310.1 - 8.8 6.4 10.0 1.8 8.6 0.8 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF627) TRP PF06011.12 KDO33311.1 - 5.3e-13 48.5 7.0 9.7e-13 47.6 7.0 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TPR_2 PF07719.17 KDO33312.1 - 4.1e-13 48.4 19.0 0.00057 19.8 2.6 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33312.1 - 4.1e-09 36.0 8.7 0.036 14.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33312.1 - 6.7e-09 35.2 13.8 0.01 15.6 0.2 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33312.1 - 1.7e-07 31.6 8.9 0.00018 22.0 1.6 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33312.1 - 2.1e-07 31.1 17.4 0.0022 18.2 3.3 4.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33312.1 - 3.6e-06 27.3 10.9 0.061 14.2 0.5 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33312.1 - 4.3e-06 27.3 15.6 0.0048 17.5 2.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33312.1 - 4.3e-05 23.1 9.0 0.035 13.8 0.1 3.1 3 0 0 3 3 3 2 TPR repeat TPR_21 PF09976.9 KDO33312.1 - 0.0022 17.7 4.4 0.6 9.8 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KDO33312.1 - 0.0035 17.2 11.7 0.43 10.7 0.2 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat Sel1 PF08238.12 KDO33312.1 - 0.013 16.2 1.0 0.013 16.2 1.0 4.7 6 0 0 6 6 6 0 Sel1 repeat ANAPC3 PF12895.7 KDO33312.1 - 0.033 14.4 12.8 3.8 7.8 5.2 3.9 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KDO33312.1 - 0.061 13.2 12.5 13 5.8 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33312.1 - 0.067 13.8 11.5 2.2 9.1 0.2 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33312.1 - 0.11 12.9 8.1 1.4 9.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KDO33312.1 - 0.25 11.4 7.8 4.8 7.3 1.2 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 KDO33312.1 - 0.74 9.5 7.4 0.4 10.4 1.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 KDO33312.1 - 5.9 7.8 7.7 1.1e+02 3.9 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 KDO33312.1 - 7.8 5.9 11.7 3 7.2 0.1 3.6 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like Sod_Fe_C PF02777.18 KDO33313.1 - 7.8e-38 128.8 2.3 1.3e-37 128.1 0.1 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KDO33313.1 - 2.3e-30 104.9 2.1 3.8e-30 104.2 2.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Rer1 PF03248.13 KDO33314.1 - 9e-67 224.1 8.0 1.1e-66 223.8 8.0 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 KDO33314.1 - 0.0064 16.1 0.2 0.0064 16.1 0.2 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2208) DUF2228 PF10228.9 KDO33316.1 - 1.9e-41 142.5 0.0 4.6e-41 141.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) DUF2306 PF10067.9 KDO33317.1 - 1.5e-12 48.0 12.8 1.5e-12 48.0 12.8 2.2 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) FAD_binding_6 PF00970.24 KDO33317.1 - 6.9e-07 29.6 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KDO33317.1 - 0.00064 19.9 0.3 0.027 14.6 0.1 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF420 PF04238.12 KDO33317.1 - 0.011 16.0 0.7 0.011 16.0 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF420) DUF2975 PF11188.8 KDO33317.1 - 4.7 7.1 18.2 0.18 11.7 3.5 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2975) Fumarate_red_C PF02300.17 KDO33317.1 - 6.8 6.8 12.9 4.3 7.4 1.4 3.2 3 0 0 3 3 3 0 Fumarate reductase subunit C Ribosomal_L36e PF01158.18 KDO33318.1 - 2.2e-34 117.6 2.3 2.5e-34 117.4 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Aha1_N PF09229.11 KDO33319.1 - 4.4e-17 62.6 0.0 9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 KDO33319.1 - 3.1e-09 36.2 4.9 0.00018 21.2 0.1 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33319.1 - 6.7e-08 32.1 5.3 0.0041 17.1 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33319.1 - 0.00015 21.7 9.3 0.0012 18.9 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33319.1 - 0.00096 19.8 4.3 0.0013 19.3 0.4 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33319.1 - 0.001 19.6 3.1 0.002 18.6 3.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat ox_reductase_C PF08635.10 KDO33319.1 - 0.071 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain TPR_11 PF13414.6 KDO33319.1 - 0.11 12.2 0.0 0.11 12.2 0.0 3.2 3 1 1 4 4 4 0 TPR repeat TPR_12 PF13424.6 KDO33319.1 - 0.21 11.9 2.7 3.4 8.0 0.5 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat SMP_LBD PF17047.5 KDO33320.1 - 1.4e-16 60.5 0.0 2.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KDO33320.1 - 2e-08 34.4 0.1 0.0034 17.6 0.0 2.8 2 0 0 2 2 2 2 C2 domain MMM1 PF10296.9 KDO33320.1 - 0.032 13.3 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 CCDC-167 PF15188.6 KDO33321.1 - 0.24 11.7 2.9 0.47 10.8 2.3 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 KDO33321.1 - 0.66 8.8 5.4 1 8.2 5.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AA_permease_2 PF13520.6 KDO33322.1 - 1.4e-41 142.7 36.0 2.1e-41 142.2 36.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.12 KDO33322.1 - 3.6 7.8 8.3 0.11 12.6 0.3 2.6 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 GMC_oxred_N PF00732.19 KDO33323.1 - 1.3e-48 165.9 0.7 1.8e-48 165.5 0.2 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KDO33323.1 - 1.1e-22 81.0 0.7 4.6e-22 79.1 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KDO33323.1 - 9.9e-06 24.9 4.3 4.6e-05 22.7 3.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KDO33323.1 - 8.4e-05 22.7 2.8 0.00021 21.4 2.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KDO33323.1 - 8.4e-05 22.3 9.2 0.066 12.8 3.2 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KDO33323.1 - 0.00012 21.4 0.3 0.00042 19.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KDO33323.1 - 0.0018 17.6 1.8 0.0031 16.8 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KDO33323.1 - 0.0086 15.3 0.3 0.024 13.9 0.3 1.7 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KDO33323.1 - 0.01 14.6 1.2 0.01 14.6 1.2 1.8 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KDO33323.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KDO33323.1 - 0.084 12.1 0.1 0.3 10.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO33323.1 - 0.098 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KDO33323.1 - 0.11 11.5 0.4 0.32 10.0 0.4 1.8 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3433 PF11915.8 KDO33323.1 - 0.63 10.5 4.1 0.23 11.9 0.2 2.3 3 0 0 3 3 1 0 Protein of unknown function (DUF3433) FAD_oxidored PF12831.7 KDO33323.1 - 1.2 8.4 5.2 2.4 7.4 5.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPR_2 PF07719.17 KDO33324.1 - 8e-09 35.0 9.7 0.00072 19.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33324.1 - 0.00076 19.2 4.5 0.44 10.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33324.1 - 0.006 17.1 4.7 0.006 17.1 4.7 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33324.1 - 0.027 15.3 0.6 0.027 15.3 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO33324.1 - 0.62 10.3 7.4 1.8 8.8 7.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HeLo PF14479.6 KDO33324.1 - 1.6 8.6 6.3 0.5 10.2 0.9 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation SRP40_C PF05022.12 KDO33325.1 - 2.7e-23 82.6 0.5 2.7e-23 82.6 0.5 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain G-patch PF01585.23 KDO33326.1 - 4.5e-13 48.9 1.2 4.5e-13 48.9 1.2 2.1 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KDO33326.1 - 1.7e-10 40.8 0.3 1.7e-10 40.8 0.3 2.6 2 0 0 2 2 2 1 G-patch domain HA2 PF04408.23 KDO33326.1 - 0.1 12.9 1.4 0.15 12.4 1.4 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) RR_TM4-6 PF06459.12 KDO33326.1 - 0.21 11.4 5.4 0.24 11.2 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FmiP_Thoc5 PF09766.9 KDO33326.1 - 0.21 10.8 6.9 0.26 10.5 6.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TSGP1 PF07771.11 KDO33326.1 - 0.5 10.5 10.6 0.76 9.9 10.6 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 SR-25 PF10500.9 KDO33326.1 - 2.2 7.9 24.1 3.2 7.3 23.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2428 PF10350.9 KDO33326.1 - 3.4 6.9 6.9 14 4.8 0.0 2.1 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Presenilin PF01080.17 KDO33326.1 - 8.5 5.0 5.5 9 4.9 5.5 1.1 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 KDO33327.1 - 6.2e-87 292.4 0.6 7.3e-86 288.9 0.6 2.2 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 HSBP1 PF06825.12 KDO33328.1 - 1.7e-25 88.6 3.5 2e-25 88.4 3.5 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Laminin_I PF06008.14 KDO33328.1 - 0.013 15.3 0.5 0.1 12.3 0.5 1.9 1 1 0 1 1 1 0 Laminin Domain I CLZ PF16526.5 KDO33328.1 - 0.013 15.9 0.2 0.02 15.2 0.2 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 KDO33328.1 - 0.049 13.9 0.2 0.064 13.6 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Erythro-docking PF09277.11 KDO33328.1 - 0.051 13.5 0.1 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Erythronolide synthase, docking YvrJ PF12841.7 KDO33328.1 - 0.11 12.1 0.4 0.44 10.1 0.1 2.0 2 0 0 2 2 2 0 YvrJ protein family PHD PF00628.29 KDO33329.1 - 2.2e-10 40.3 6.7 6.7e-10 38.7 6.7 1.9 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 KDO33329.1 - 0.0016 18.7 5.9 0.0016 18.7 5.9 3.0 4 0 0 4 4 4 1 Ring finger domain Prok-RING_1 PF14446.6 KDO33329.1 - 0.032 14.2 4.2 0.032 14.2 4.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 KDO33329.1 - 0.11 12.9 6.5 0.079 13.3 2.6 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain C1_2 PF03107.16 KDO33329.1 - 0.29 11.5 6.8 0.25 11.7 3.7 2.4 2 0 0 2 2 2 0 C1 domain zf-Sec23_Sec24 PF04810.15 KDO33329.1 - 0.39 10.8 3.4 0.51 10.4 1.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Dendrin PF15498.6 KDO33332.1 - 0.055 12.2 2.3 0.094 11.4 2.3 1.3 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin DHR-2 PF06920.13 KDO33333.1 - 1.6e-33 116.1 0.0 2.6e-29 102.3 0.0 3.0 1 1 1 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 KDO33333.1 - 4e-26 92.0 0.0 8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DnaJ PF00226.31 KDO33334.1 - 2.1e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KDO33334.1 - 5.4e-05 23.2 1.3 0.00039 20.4 1.3 2.0 1 1 0 1 1 1 1 Pam16 Sensor PF13796.6 KDO33335.1 - 0.19 11.8 21.5 0.15 12.1 18.6 1.9 1 1 1 2 2 2 0 Putative sensor Thioredoxin PF00085.20 KDO33337.1 - 2e-28 98.4 0.0 2.5e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KDO33337.1 - 7.6e-07 29.6 0.0 0.0038 17.7 0.0 2.5 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KDO33337.1 - 1.4e-06 28.6 0.1 1.3 9.4 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like HyaE PF07449.11 KDO33337.1 - 2e-05 24.5 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KDO33337.1 - 0.00021 21.4 0.1 0.0072 16.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like TPPK_C PF12555.8 KDO33337.1 - 0.092 12.8 0.2 0.3 11.2 0.2 1.9 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Thioredoxin PF00085.20 KDO33338.1 - 4.8e-137 447.3 0.0 4.9e-31 106.8 0.0 6.2 6 0 0 6 6 6 6 Thioredoxin Thioredoxin_2 PF13098.6 KDO33338.1 - 2.9e-30 104.9 0.8 3.3e-05 24.3 0.1 8.3 6 3 0 6 6 6 6 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KDO33338.1 - 8.6e-25 86.7 0.4 0.0029 17.7 0.0 6.7 6 0 0 6 6 6 6 Thioredoxin-like Thioredoxin_8 PF13905.6 KDO33338.1 - 3.2e-23 81.9 5.4 0.088 13.1 0.0 11.0 6 6 5 11 11 11 6 Thioredoxin-like AhpC-TSA PF00578.21 KDO33338.1 - 9e-19 67.6 0.1 0.0064 16.4 0.0 6.2 6 0 0 6 6 6 5 AhpC/TSA family HyaE PF07449.11 KDO33338.1 - 1.4e-18 66.9 0.1 0.0062 16.5 0.0 6.4 6 0 0 6 6 6 5 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 KDO33338.1 - 1.2e-17 64.2 0.0 0.0075 15.6 0.0 6.0 5 1 0 6 6 6 4 OST3 / OST6 family, transporter family TraF PF13728.6 KDO33338.1 - 6.9e-16 58.7 0.4 0.0033 17.3 0.0 6.4 7 0 0 7 7 7 4 F plasmid transfer operon protein Glutaredoxin PF00462.24 KDO33338.1 - 2.2e-12 47.0 0.2 0.04 14.1 0.0 6.4 6 0 0 6 6 6 3 Glutaredoxin Thioredoxin_3 PF13192.6 KDO33338.1 - 4e-12 46.0 0.0 0.28 11.3 0.0 6.0 6 0 0 6 6 6 3 Thioredoxin domain Thioredoxin_9 PF14595.6 KDO33338.1 - 5.2e-12 45.7 0.0 0.084 12.6 0.0 5.9 6 0 0 6 6 6 3 Thioredoxin Thioredoxin_6 PF13848.6 KDO33338.1 - 4.5e-09 36.5 0.0 3.8 7.4 0.0 5.7 6 0 0 6 6 6 2 Thioredoxin-like domain Redoxin PF08534.10 KDO33338.1 - 7.6e-08 32.2 3.0 0.12 12.1 0.0 6.3 6 1 1 7 7 7 1 Redoxin DUF836 PF05768.14 KDO33338.1 - 1.3e-07 31.9 0.0 4.2 7.8 0.0 5.3 6 0 0 6 6 6 2 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KDO33338.1 - 2.3e-05 24.2 0.5 0.2 11.4 0.0 5.1 5 1 1 6 6 6 1 DSBA-like thioredoxin domain ERp29_N PF07912.13 KDO33338.1 - 0.0014 18.7 0.2 3.5 7.8 0.0 4.4 5 0 0 5 5 5 1 ERp29, N-terminal domain Calsequestrin PF01216.17 KDO33338.1 - 0.0065 15.5 0.3 7.5 5.5 0.0 3.4 4 0 0 4 4 4 2 Calsequestrin Thioredoxin_4 PF13462.6 KDO33338.1 - 0.03 14.5 1.3 25 5.0 0.0 5.2 6 1 1 7 7 7 0 Thioredoxin Hydantoinase_B PF02538.14 KDO33339.1 - 9.1e-215 713.9 0.3 1.2e-214 713.5 0.3 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KDO33339.1 - 1.8e-96 322.9 0.0 4e-96 321.7 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KDO33339.1 - 1.3e-60 204.2 0.4 2.3e-58 196.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Peptidase_C1 PF00112.23 KDO33340.1 - 7.7e-60 202.7 8.3 7.7e-60 202.7 8.3 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO33340.1 - 1.6e-05 23.9 1.1 0.0096 14.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family HTH_39 PF14090.6 KDO33342.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Phos_pyr_kin PF08543.12 KDO33344.1 - 1.9e-17 63.5 0.0 2.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KDO33344.1 - 2e-10 40.5 0.0 6.1e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase TSC22 PF01166.18 KDO33344.1 - 0.035 14.4 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family PCI PF01399.27 KDO33345.1 - 7.7e-18 64.9 0.4 3.8e-17 62.7 0.4 2.2 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.6 KDO33345.1 - 6.3e-05 23.5 0.0 5 8.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Cas_St_Csn2 PF16813.5 KDO33345.1 - 0.00065 18.9 0.4 0.0011 18.2 0.4 1.3 1 0 0 1 1 1 1 CRISPR-associated protein Csn2 subfamily St ParcG PF10274.9 KDO33345.1 - 0.052 13.7 0.7 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Parkin co-regulated protein RPN6_N PF18055.1 KDO33345.1 - 0.064 13.6 0.2 0.33 11.3 0.0 2.3 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_7 PF13176.6 KDO33345.1 - 0.11 12.6 0.0 20 5.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 KDO33346.1 - 5.9e-20 71.5 0.0 1.9e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO33346.1 - 9.6e-07 28.9 0.3 0.00097 19.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KDO33346.1 - 3.4e-05 23.4 0.0 4.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO33346.1 - 8e-05 22.8 0.3 0.031 14.3 0.3 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KDO33346.1 - 0.00019 21.1 0.6 0.048 13.2 0.2 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IIGP PF05049.13 KDO33346.1 - 0.0036 16.4 0.7 0.014 14.5 0.7 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KDO33346.1 - 0.019 14.3 0.0 0.067 12.5 0.0 1.9 1 1 0 2 2 2 0 Septin SRPRB PF09439.10 KDO33346.1 - 0.045 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 KDO33346.1 - 0.073 13.3 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KDO33346.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO33346.1 - 0.41 11.1 1.8 4.4 7.8 1.8 2.1 1 1 0 1 1 1 0 AAA domain Choline_kinase PF01633.20 KDO33347.1 - 2.6e-57 193.8 0.0 3.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KDO33347.1 - 2.4e-13 50.6 0.1 5.4e-13 49.4 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KDO33347.1 - 3.3e-05 23.4 0.1 5.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase CDP-OH_P_transf PF01066.21 KDO33348.1 - 1.8e-15 57.5 0.2 4.7e-15 56.1 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Choline_kinase PF01633.20 KDO33349.1 - 1e-57 195.1 0.0 1.5e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KDO33349.1 - 2.4e-13 50.6 0.0 5e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KDO33349.1 - 3.5e-05 23.3 0.1 5.4e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Haspin_kinase PF12330.8 KDO33349.1 - 0.21 10.5 0.0 0.92 8.4 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 KDO33350.1 - 1e-43 149.4 0.0 2.2e-43 148.3 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KDO33350.1 - 2.3e-06 27.7 0.1 9.3e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family COMM_domain PF07258.14 KDO33351.1 - 1.4e-12 47.5 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 COMM domain RE_Bsp6I PF09504.10 KDO33351.1 - 0.2 11.2 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Choline_kinase PF01633.20 KDO33352.1 - 1.4e-51 175.1 0.0 2.3e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KDO33352.1 - 4.1e-20 72.7 0.4 9.7e-20 71.5 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KDO33352.1 - 3.5e-06 26.6 0.2 5.5e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase LRR_6 PF13516.6 KDO33353.1 - 2.7e-07 30.1 7.3 0.007 16.3 0.1 4.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 KDO33353.1 - 0.11 12.3 4.6 3.4 7.5 1.0 3.7 3 2 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 KDO33353.1 - 0.14 12.8 0.5 12 7.0 0.1 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 KDO33353.1 - 0.59 10.6 6.7 2.7 8.5 0.2 4.1 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) DUF1943 PF09172.11 KDO33353.1 - 7.3 5.7 9.1 0.8 8.9 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) IFRD PF05004.13 KDO33354.1 - 1.1e-49 169.2 3.5 1.5e-49 168.8 3.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 KDO33354.1 - 0.003 17.5 0.2 0.024 14.6 0.0 2.6 4 0 0 4 4 4 1 UME (NUC010) domain ParcG PF10274.9 KDO33354.1 - 0.0087 16.2 0.0 0.13 12.4 0.0 2.2 2 1 0 2 2 2 1 Parkin co-regulated protein HEAT_2 PF13646.6 KDO33354.1 - 0.011 16.1 3.3 3 8.3 0.0 3.9 2 1 2 4 4 4 0 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO33354.1 - 0.029 14.9 1.2 16 6.2 0.1 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KDO33354.1 - 0.75 10.4 3.2 38 4.9 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat Solute_trans_a PF03619.16 KDO33355.1 - 1.6e-08 34.4 10.5 2.1e-08 34.0 10.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha NrsF PF06532.11 KDO33355.1 - 1.7 8.3 16.6 0.04 13.6 8.8 2.1 2 1 1 3 3 3 0 Negative regulator of sigma F PAXNEB PF05625.11 KDO33357.1 - 7.6e-68 229.3 0.1 9.9e-68 228.9 0.1 1.1 1 0 0 1 1 1 1 PAXNEB protein PMD PF10536.9 KDO33357.1 - 0.021 13.9 0.1 0.044 12.9 0.1 1.5 1 0 0 1 1 1 0 Plant mobile domain RF-1 PF00472.20 KDO33358.1 - 1.1e-20 73.7 0.7 1.8e-20 73.0 0.7 1.3 1 0 0 1 1 1 1 RF-1 domain SDA1 PF05285.12 KDO33358.1 - 0.0042 16.6 18.6 0.0052 16.3 18.6 1.3 1 0 0 1 1 1 1 SDA1 Cwf_Cwc_15 PF04889.12 KDO33358.1 - 0.013 15.3 23.7 0.017 14.9 23.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KDO33358.1 - 0.031 13.6 21.3 0.038 13.4 21.3 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 KDO33358.1 - 0.04 13.9 20.3 0.045 13.7 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3295 PF11702.8 KDO33358.1 - 0.17 11.2 15.8 0.23 10.8 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DNA_pol_phi PF04931.13 KDO33358.1 - 0.2 9.7 27.1 0.24 9.4 27.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 KDO33358.1 - 0.2 11.2 14.8 0.23 11.0 14.8 1.2 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 KDO33358.1 - 0.21 11.4 13.3 0.24 11.3 13.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pox_Ag35 PF03286.14 KDO33358.1 - 0.26 11.0 16.8 0.38 10.5 16.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 KDO33358.1 - 0.52 8.5 17.2 0.55 8.5 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KDO33358.1 - 0.54 8.4 24.6 0.63 8.2 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KDO33358.1 - 0.66 10.2 22.2 0.88 9.8 22.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.10 KDO33358.1 - 8.7 6.6 15.7 13 6.1 15.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.15 KDO33358.1 - 9.8 4.8 12.5 10 4.8 12.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EGF_2 PF07974.13 KDO33359.1 - 6.3e-13 48.8 67.7 7.8e-05 23.0 6.8 5.5 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 KDO33359.1 - 5.5 7.4 48.9 0.23 11.8 1.9 5.8 5 0 0 5 5 5 0 EGF-like domain Sulfate_transp PF00916.20 KDO33360.1 - 1.7e-16 59.9 15.5 1.2e-11 44.0 5.1 2.2 2 0 0 2 2 2 2 Sulfate permease family Mito_carr PF00153.27 KDO33361.1 - 4.7e-59 196.3 3.4 2.3e-20 72.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KDO33361.1 - 0.026 15.0 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KDO33361.1 - 0.15 11.6 0.1 26 4.7 0.0 2.6 2 0 0 2 2 2 0 EF hand Kelch_5 PF13854.6 KDO33362.1 - 3e-27 94.1 0.1 2.2e-07 30.7 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KDO33362.1 - 1.4e-26 92.2 13.6 1.2e-09 38.0 0.1 6.1 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO33362.1 - 2.6e-22 78.3 0.3 3.1e-09 36.8 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KDO33362.1 - 3.3e-21 74.4 4.5 9.9e-08 31.7 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KDO33362.1 - 6.1e-18 64.6 6.7 8.5e-07 29.1 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO33362.1 - 8.2e-17 60.5 10.2 1.5e-08 34.0 0.0 6.2 6 0 0 6 6 6 3 Kelch motif RAG2 PF03089.14 KDO33362.1 - 0.023 13.7 0.0 0.075 12.0 0.0 1.9 2 0 0 2 2 2 0 Recombination activating protein 2 DUF5538 PF17692.1 KDO33362.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5538) TFIIS_C PF01096.18 KDO33363.1 - 4.6e-19 68.0 4.4 4.6e-19 68.0 4.4 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KDO33363.1 - 9.2e-10 38.2 2.9 9.2e-10 38.2 2.9 2.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KDO33363.1 - 0.00013 21.9 1.3 0.00013 21.9 1.3 2.6 2 1 0 2 2 2 1 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 KDO33363.1 - 0.013 15.4 2.8 0.013 15.4 2.8 2.4 2 0 0 2 2 2 0 Nudix N-terminal YacG PF03884.14 KDO33363.1 - 0.018 14.7 2.2 0.018 14.7 2.2 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-GRF PF06839.12 KDO33363.1 - 0.026 14.6 0.7 0.026 14.6 0.7 2.4 2 1 0 2 2 2 0 GRF zinc finger zf-ribbon_3 PF13248.6 KDO33363.1 - 0.69 9.4 13.5 0.38 10.2 0.7 3.9 4 1 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 KDO33363.1 - 0.79 10.1 8.3 1.5 9.3 1.0 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar HypA PF01155.19 KDO33363.1 - 3.5 7.7 8.8 0.17 11.9 0.6 2.6 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Terminase_GpA PF05876.12 KDO33363.1 - 5.7 5.4 8.1 0.12 10.9 1.6 1.5 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) RecR PF02132.15 KDO33363.1 - 6.9 6.3 8.6 8.3 6.1 3.5 2.5 2 1 0 2 2 2 0 RecR protein DpnI PF06044.12 KDO33363.1 - 7.5 6.1 8.6 0.83 9.3 0.7 2.0 1 1 0 2 2 2 0 Dam-replacing family Rubredoxin PF00301.20 KDO33363.1 - 8.4 6.5 14.8 6.1 6.9 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin Methyltransf_11 PF08241.12 KDO33364.1 - 1.4e-15 57.7 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33364.1 - 3.7e-12 46.8 0.1 6.6e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33364.1 - 3.2e-10 40.0 0.0 3.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33364.1 - 2.2e-07 31.5 0.0 3.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO33364.1 - 1.5e-05 24.5 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KDO33364.1 - 2.2e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KDO33364.1 - 0.01 15.6 0.1 0.036 13.8 0.0 1.9 1 1 1 2 2 2 0 DNA methylase CMAS PF02353.20 KDO33364.1 - 0.02 14.2 0.4 0.023 14.0 0.4 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KDO33364.1 - 0.049 13.1 0.3 0.1 12.1 0.1 1.6 2 1 0 2 2 2 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 KDO33364.1 - 0.062 12.4 0.4 0.12 11.4 0.4 1.6 1 1 0 1 1 1 0 DREV methyltransferase Peptidase_M16 PF00675.20 KDO33365.1 - 1.9e-34 118.8 0.0 4.7e-34 117.5 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO33365.1 - 8.2e-34 117.2 0.0 1.3e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain muHD PF10291.9 KDO33366.1 - 0.11 11.9 0.7 0.3 10.5 0.1 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain sCache_3_2 PF17203.4 KDO33366.1 - 0.2 11.8 2.3 0.63 10.2 2.3 1.8 1 0 0 1 1 1 0 Single cache domain 3 Pyr_redox_2 PF07992.14 KDO33367.1 - 6.8e-42 143.7 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO33367.1 - 1.1e-09 38.7 0.0 4.8e-07 30.2 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KDO33367.1 - 1.4e-08 33.6 0.3 0.00037 19.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO33367.1 - 4.6e-08 33.4 0.1 0.0045 17.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO33367.1 - 3.6e-07 29.9 0.1 0.03 14.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO33367.1 - 1e-06 28.2 1.3 0.0069 16.2 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO33367.1 - 0.0018 17.7 0.6 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 EF hand LRR_8 PF13855.6 KDO33368.1 - 7.5e-09 35.2 3.5 2.3e-06 27.3 0.2 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KDO33368.1 - 7.8e-07 29.3 1.3 2.3e-05 24.6 0.1 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO33368.1 - 0.022 14.8 0.4 9.2 6.6 0.0 3.3 2 0 0 2 2 2 0 Leucine Rich repeat Notch PF00066.17 KDO33368.1 - 0.19 12.2 12.0 0.51 10.8 12.0 1.8 1 0 0 1 1 1 0 LNR domain WD40 PF00400.32 KDO33370.1 - 1.7e-48 161.6 8.5 3.7e-08 33.9 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KDO33370.1 - 8.9e-20 70.8 9.8 1.4e-19 70.2 9.8 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KDO33370.1 - 5.3e-15 55.5 0.0 0.0017 18.6 0.0 6.0 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO33370.1 - 4.9e-09 35.6 0.2 0.18 10.7 0.0 4.8 2 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KDO33370.1 - 4.8e-05 22.8 0.0 0.75 9.1 0.0 3.7 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KDO33370.1 - 0.00015 21.6 4.4 45 4.1 0.0 6.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat CENP-Q PF13094.6 KDO33370.1 - 0.0014 18.9 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit WD40_like PF17005.5 KDO33370.1 - 0.0062 15.9 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 KDO33370.1 - 0.011 14.4 0.0 0.086 11.5 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Filament PF00038.21 KDO33370.1 - 0.014 15.0 5.6 0.021 14.4 5.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein BAR_3 PF16746.5 KDO33370.1 - 0.07 12.8 2.0 0.11 12.2 2.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family DUF3450 PF11932.8 KDO33370.1 - 0.37 10.0 5.8 0.62 9.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Proteasome_A_N PF10584.9 KDO33370.1 - 0.39 10.4 2.7 86 3.0 0.1 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1664 PF07889.12 KDO33370.1 - 0.91 9.6 3.8 1.6 8.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase_Tyr PF07714.17 KDO33371.1 - 2.5e-39 135.1 0.0 4.1e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO33371.1 - 6.7e-36 124.0 0.0 2.5e-28 99.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 KDO33371.1 - 0.00065 19.4 0.2 0.0015 18.3 0.2 1.7 1 1 0 1 1 1 1 Leucine rich repeat Pkinase_fungal PF17667.1 KDO33371.1 - 0.0023 16.8 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_4 PF12799.7 KDO33371.1 - 0.0071 16.7 1.3 1.9 9.0 0.0 2.7 1 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO33371.1 - 0.026 14.6 0.1 18 5.7 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat APH PF01636.23 KDO33371.1 - 0.032 14.1 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4381 PF14316.6 KDO33371.1 - 0.066 13.5 1.3 5.7 7.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LRR_1 PF00560.33 KDO33371.1 - 0.16 12.6 1.0 1.2e+02 3.8 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 KDO33373.1 - 4.7e-45 154.0 0.0 6.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33373.1 - 1e-40 139.7 0.0 1.6e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO33373.1 - 0.0012 17.7 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DEC1 PF15859.5 KDO33373.1 - 0.032 14.2 0.1 0.095 12.7 0.1 1.8 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family GP44 PF17510.2 KDO33374.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Gene product 44 Pkinase_Tyr PF07714.17 KDO33375.1 - 2e-43 148.6 0.0 2.9e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO33375.1 - 4.2e-42 144.3 0.0 6e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO33375.1 - 0.051 12.4 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KDO33375.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.29 KDO33376.1 - 4.4e-45 153.3 0.0 5e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO33376.1 - 7.4e-11 41.7 0.7 7.9e-07 28.8 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KDO33376.1 - 3e-08 34.2 9.0 0.00029 21.3 1.6 4.2 2 2 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KDO33376.1 - 6.3e-08 32.5 0.1 0.0091 15.7 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 KDO33376.1 - 3.6e-07 30.5 0.7 0.038 14.2 0.3 3.8 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KDO33376.1 - 2.6e-06 27.5 0.1 0.057 13.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO33376.1 - 1.1e-05 25.7 0.0 0.032 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO33376.1 - 0.00011 21.9 0.5 0.0068 16.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KDO33376.1 - 0.00013 22.5 0.1 0.34 11.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 KDO33376.1 - 0.00016 20.9 0.1 0.54 9.4 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KDO33376.1 - 0.00065 19.6 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein RNA_helicase PF00910.22 KDO33376.1 - 0.0015 18.9 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 KDO33376.1 - 0.004 17.7 0.0 3.6 8.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 KDO33376.1 - 0.0044 16.8 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KDO33376.1 - 0.011 15.7 4.0 5.4 6.9 0.3 4.0 2 2 1 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 KDO33376.1 - 0.013 14.8 0.0 0.42 9.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 KDO33376.1 - 0.017 15.6 0.0 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO33376.1 - 0.019 14.7 6.4 0.46 10.2 0.4 3.7 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 KDO33376.1 - 0.067 13.4 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KDO33376.1 - 0.07 12.6 0.1 8 5.9 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region Hpr_kinase_C PF07475.12 KDO33376.1 - 0.079 12.5 0.3 13 5.3 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain MMR_HSR1 PF01926.23 KDO33376.1 - 0.12 12.4 0.0 1.3 9.2 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KDO33376.1 - 0.19 11.4 0.7 4.4 7.0 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KDO33376.1 - 0.36 11.2 2.3 4.5 7.6 0.9 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO33376.1 - 0.44 10.1 3.9 6.9 6.2 0.2 3.0 2 1 1 3 3 3 0 AAA domain SRP54 PF00448.22 KDO33376.1 - 1.3 8.7 5.5 2.1 8.0 0.2 3.3 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AT_hook PF02178.19 KDO33380.1 - 0.0001 21.7 67.3 0.046 13.6 3.3 6.9 6 0 0 6 6 6 6 AT hook motif zf-C2H2_4 PF13894.6 KDO33381.1 - 0.029 15.2 0.3 0.029 15.2 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KDO33381.1 - 0.031 14.7 11.1 0.065 13.7 0.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Cyclin_N PF00134.23 KDO33381.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DZR PF12773.7 KDO33382.1 - 0.0032 17.4 14.2 0.014 15.4 14.3 2.0 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO33382.1 - 0.0034 17.0 16.3 0.013 15.2 6.4 2.5 2 1 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 KDO33382.1 - 0.079 12.6 0.8 0.079 12.6 0.8 4.0 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain PolC_DP2 PF03833.13 KDO33382.1 - 0.66 7.8 1.2 0.88 7.4 1.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 UPF0547 PF10571.9 KDO33382.1 - 2.9 8.1 19.0 1.9 8.6 6.7 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DSPc PF00782.20 KDO33384.1 - 2.4e-32 111.6 0.1 3.5e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO33384.1 - 2.2e-06 27.4 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO33384.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate MoCF_biosynth PF00994.24 KDO33385.1 - 3.4e-55 185.7 0.5 2.7e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KDO33385.1 - 1.2e-41 142.1 1.7 1.8e-41 141.5 1.7 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KDO33385.1 - 6.9e-13 48.6 0.0 3.1e-12 46.5 0.0 2.2 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) 7TMR-HDED PF07697.11 KDO33385.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 7TM-HD extracellular Prenyltrans PF00432.21 KDO33386.1 - 0.00018 21.2 0.5 7.9 6.3 0.0 3.9 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans PF00432.21 KDO33387.1 - 2.9e-12 46.1 1.2 0.0008 19.1 0.4 3.2 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat LTXXQ PF07813.12 KDO33388.1 - 0.14 12.9 7.3 1.6 9.5 7.1 2.5 1 1 0 1 1 1 0 LTXXQ motif family protein APG6_N PF17675.1 KDO33388.1 - 0.14 12.7 3.0 0.22 12.0 3.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GAGA_bind PF06217.12 KDO33388.1 - 0.29 11.4 3.5 0.45 10.8 3.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family YkyA PF10368.9 KDO33388.1 - 0.32 10.6 8.9 0.49 10.1 8.3 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Dynamin_N PF00350.23 KDO33390.1 - 4.8e-12 46.3 0.0 3.9e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KDO33390.1 - 4.1e-06 26.9 0.0 2.8e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 KDO33390.1 - 0.0051 17.4 0.1 0.26 11.9 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5600) Roc PF08477.13 KDO33390.1 - 0.029 14.6 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KDO33390.1 - 0.03 13.9 0.1 8.3 5.9 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 KDO33390.1 - 0.057 13.8 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain SLATT_1 PF18181.1 KDO33390.1 - 0.086 12.8 1.1 0.23 11.4 1.1 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 RsgA_GTPase PF03193.16 KDO33390.1 - 0.091 12.7 0.0 1.5 8.7 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 KDO33390.1 - 0.15 11.4 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 AIG1 family HypA PF01155.19 KDO33391.1 - 0.047 13.7 3.7 0.063 13.3 3.7 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 KDO33391.1 - 4.5 7.4 9.5 0.34 11.0 5.1 1.4 1 1 0 1 1 1 0 Transposase zinc-binding domain SNF2_N PF00176.23 KDO33392.1 - 5.4e-77 258.9 0.1 1.4e-76 257.5 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO33392.1 - 2.5e-19 69.7 0.0 7.3e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KDO33392.1 - 1.6e-09 37.5 9.4 1.6e-09 37.5 9.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO33392.1 - 9.7e-08 31.7 10.7 3.1e-07 30.1 10.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KDO33392.1 - 1.7e-07 31.4 0.0 5.3e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KDO33392.1 - 4.2e-07 29.7 8.5 4.2e-07 29.7 8.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO33392.1 - 8.2e-07 29.3 9.5 8.2e-07 29.3 9.5 2.3 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO33392.1 - 1.2e-06 28.3 8.0 1.2e-06 28.3 8.0 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 DEAD PF00270.29 KDO33392.1 - 4e-06 26.7 0.0 9.8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KDO33392.1 - 8.3e-06 25.7 8.8 8.3e-06 25.7 8.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO33392.1 - 0.00015 21.7 10.8 0.00053 20.0 10.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 KDO33392.1 - 0.03 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HIRAN PF08797.11 KDO33392.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain zf-RanBP PF00641.18 KDO33392.1 - 0.14 11.5 8.2 0.012 14.9 2.6 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-rbx1 PF12678.7 KDO33392.1 - 2.5 8.5 11.5 0.36 11.1 6.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KDO33392.1 - 3.9 7.7 18.0 0.037 14.2 9.9 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 DZR PF12773.7 KDO33392.1 - 5.4 7.1 16.6 0.79 9.8 1.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO33392.1 - 6.4 6.6 8.3 16 5.4 2.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Methyltransf_4 PF02390.17 KDO33393.1 - 2e-40 138.1 0.0 2.3e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KDO33393.1 - 2.8e-05 24.7 0.0 8.6e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33393.1 - 8.9e-05 22.3 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33393.1 - 0.0065 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO33393.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KDO33393.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) BUD22 PF09073.10 KDO33394.1 - 2.1e-15 57.0 30.2 2.7e-10 40.2 21.8 3.4 1 1 1 2 2 2 2 BUD22 NusA_N PF08529.11 KDO33394.1 - 0.063 13.6 0.6 0.84 10.0 0.1 2.3 2 0 0 2 2 2 0 NusA N-terminal domain Bap31 PF05529.12 KDO33395.1 - 0.00082 19.2 7.9 0.28 11.0 4.7 2.0 1 1 1 2 2 2 2 Bap31/Bap29 transmembrane region TIM21 PF08294.11 KDO33397.1 - 3e-13 49.9 0.0 4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 TIM21 EMP24_GP25L PF01105.24 KDO33398.1 - 5.7e-26 91.6 0.1 6.9e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Adaptin_N PF01602.20 KDO33399.1 - 1.2e-118 397.0 3.5 1.5e-118 396.6 3.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KDO33399.1 - 6.5e-23 81.5 0.9 6.5e-23 81.5 0.9 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 KDO33399.1 - 1.3e-15 57.9 0.0 4.1e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 KDO33399.1 - 3.5e-11 43.3 5.0 1.1e-06 28.9 0.5 4.3 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KDO33399.1 - 8.8e-05 22.9 4.0 0.0092 16.5 0.1 4.3 4 1 0 4 4 4 1 HEAT-like repeat SDA1 PF05285.12 KDO33399.1 - 0.00017 21.2 24.3 0.00031 20.3 24.3 1.3 1 0 0 1 1 1 1 SDA1 Na_trans_assoc PF06512.13 KDO33399.1 - 0.0078 16.5 9.3 0.017 15.4 6.3 2.2 2 0 0 2 2 2 1 Sodium ion transport-associated Sec7_N PF12783.7 KDO33399.1 - 0.014 15.3 1.2 0.4 10.6 0.2 2.9 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Nop14 PF04147.12 KDO33399.1 - 0.025 12.8 30.5 0.016 13.5 28.6 1.5 2 0 0 2 2 2 0 Nop14-like family HEAT PF02985.22 KDO33399.1 - 0.045 14.0 16.4 0.34 11.3 0.0 6.1 7 1 1 8 8 7 0 HEAT repeat RTP1_C1 PF10363.9 KDO33399.1 - 0.12 12.6 5.4 17 5.6 0.5 4.4 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CDC45 PF02724.14 KDO33399.1 - 0.23 9.7 22.9 0.26 9.5 21.5 1.7 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.15 KDO33399.1 - 0.69 8.6 13.1 1.9 7.2 13.1 1.7 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 KDO33399.1 - 2.8 6.3 29.1 5.2 5.4 29.1 1.3 1 0 0 1 1 1 0 Mpp10 protein GREB1 PF15782.5 KDO33399.1 - 8.7 3.3 10.8 13 2.8 10.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CMAS PF02353.20 KDO33400.1 - 7.2e-47 160.0 0.0 1.2e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF1365 PF07103.11 KDO33400.1 - 1.8e-27 96.6 0.2 4.3e-27 95.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Amino_oxidase PF01593.24 KDO33400.1 - 4.9e-17 62.4 0.6 3.5e-11 43.0 0.0 3.2 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KDO33400.1 - 9.1e-13 48.2 0.0 2.7e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_11 PF08241.12 KDO33400.1 - 1.3e-07 32.2 0.0 2.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.14 KDO33400.1 - 3.4e-07 29.8 0.0 1.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KDO33400.1 - 4.1e-07 30.6 0.0 1e-06 29.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO33400.1 - 2e-05 24.5 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 KDO33400.1 - 5e-05 23.0 0.6 0.00026 20.7 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KDO33400.1 - 7e-05 22.9 0.0 0.0044 17.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KDO33400.1 - 0.00046 19.5 0.1 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KDO33400.1 - 0.00047 20.6 0.2 0.0022 18.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KDO33400.1 - 0.0024 17.0 0.3 0.0082 15.3 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Methyltransf_12 PF08242.12 KDO33400.1 - 0.0032 18.2 0.0 0.0068 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FAD_oxidored PF12831.7 KDO33400.1 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase PCMT PF01135.19 KDO33400.1 - 0.17 11.6 0.1 1.1 8.9 0.1 2.4 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HI0933_like PF03486.14 KDO33400.1 - 0.18 10.5 0.0 0.35 9.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein APG6_N PF17675.1 KDO33402.1 - 0.0077 16.8 1.0 0.011 16.3 1.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region HALZ PF02183.18 KDO33402.1 - 0.078 13.2 0.8 0.41 10.9 0.3 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Citrate_synt PF00285.21 KDO33402.1 - 0.18 10.8 4.3 0.079 12.0 0.5 1.9 2 0 0 2 2 2 0 Citrate synthase, C-terminal domain Prenyltrans PF00432.21 KDO33403.1 - 6.5e-23 80.2 10.4 3.5e-06 26.6 0.3 6.7 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat DUF2729 PF10870.8 KDO33403.1 - 0.2 11.5 0.3 0.42 10.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DEAD PF00270.29 KDO33404.1 - 1.7e-40 138.7 0.2 7.1e-40 136.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO33404.1 - 1.4e-22 80.1 0.0 3.1e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KDO33404.1 - 8.8e-10 38.7 1.7 6.5e-09 35.9 1.7 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KDO33404.1 - 9.3e-07 29.0 0.0 3.6e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_pol_3_Rpc31 PF11705.8 KDO33404.1 - 0.00011 22.5 1.4 0.00011 22.5 1.4 2.9 1 1 2 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 BT1 PF03092.16 KDO33405.1 - 5.3e-11 41.4 8.2 1.4e-09 36.8 1.3 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 KDO33405.1 - 0.00046 19.3 1.5 0.00069 18.7 0.3 1.9 2 0 0 2 2 2 1 PUCC protein SieB PF14163.6 KDO33405.1 - 0.13 11.7 0.2 0.5 9.8 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B UAA PF08449.11 KDO33406.1 - 1.8e-64 217.9 13.9 2.1e-64 217.6 13.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KDO33406.1 - 6.7e-11 42.5 21.6 4.8e-06 26.8 8.9 3.0 2 2 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 KDO33406.1 - 1.3e-08 34.6 9.7 1.6e-06 27.7 1.8 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 KDO33406.1 - 0.00022 20.5 5.8 0.094 11.9 0.4 2.4 2 1 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 KDO33406.1 - 0.061 12.3 5.6 0.024 13.6 0.6 2.2 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 KDO33406.1 - 0.14 12.2 5.9 7.8 6.6 2.3 2.9 2 1 0 2 2 2 0 Putative transmembrane family 234 PH PF00169.29 KDO33407.1 - 3.8e-15 56.3 0.0 4.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO33407.1 - 1e-05 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO33407.1 - 0.0017 18.8 0.1 0.044 14.2 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KDO33407.1 - 0.0063 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KDO33407.1 - 0.025 14.9 0.1 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain tRNA-synt_2b PF00587.25 KDO33408.1 - 8.4e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KDO33408.1 - 3.3e-17 62.4 0.1 7.7e-17 61.2 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KDO33408.1 - 1.8e-12 47.1 0.1 2e-11 43.8 0.0 2.5 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KDO33408.1 - 6.4e-08 32.5 0.4 3.2e-07 30.3 0.1 2.4 2 1 0 2 2 2 1 TGS domain tRNA-synt_His PF13393.6 KDO33408.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase ASH PF15780.5 KDO33411.1 - 7.2e-38 128.8 13.1 5.6e-06 26.5 0.3 16.6 18 1 1 19 19 19 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KDO33411.1 - 3.8e-12 46.0 0.0 0.052 13.4 0.3 8.8 10 0 0 10 10 10 2 MSP (Major sperm protein) domain PapD-like PF14874.6 KDO33411.1 - 2.7e-09 37.1 0.1 0.00032 20.8 0.0 5.5 5 1 0 5 5 5 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 KDO33411.1 - 2.9e-06 27.4 12.8 3.8 7.8 0.0 10.1 14 1 1 15 15 15 2 Transmembrane protein 131-like MTHFR PF02219.17 KDO33412.1 - 4.1e-91 305.3 0.0 7e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ADIP PF11559.8 KDO33412.1 - 0.012 15.7 4.6 0.023 14.8 4.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TcA_TcB_BD PF18276.1 KDO33412.1 - 0.038 13.1 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain APG6_N PF17675.1 KDO33412.1 - 0.11 13.0 3.4 0.19 12.2 3.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 KDO33412.1 - 0.34 11.6 2.6 0.77 10.4 2.6 1.6 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KDO33412.1 - 1 9.8 10.5 2 8.9 9.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 KDO33412.1 - 1.1 8.3 4.2 1.6 7.7 4.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4349 PF14257.6 KDO33412.1 - 1.2 8.5 4.7 2 7.8 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HALZ PF02183.18 KDO33412.1 - 6.2 7.1 8.0 3.9 7.8 1.6 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 KDO33412.1 - 8.2 6.7 9.7 2 8.7 3.7 2.6 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II STI1 PF17830.1 KDO33413.1 - 4.8e-22 77.6 3.9 6.4e-10 38.8 0.0 3.1 3 0 0 3 3 3 2 STI1 domain Ion_trans PF00520.31 KDO33414.1 - 1.4e-156 519.0 59.3 1.3e-43 149.0 4.3 4.3 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KDO33414.1 - 2.5e-09 36.8 0.0 6.4e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KDO33414.1 - 3.5e-05 23.0 0.0 7.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO33414.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KDO33414.1 - 0.03 14.8 0.1 0.095 13.2 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair PKD_channel PF08016.12 KDO33414.1 - 2.3 6.8 60.7 0.031 13.0 0.5 9.1 8 2 2 10 10 10 0 Polycystin cation channel RGS PF00615.19 KDO33415.1 - 3e-77 256.5 13.1 4.9e-25 88.1 0.9 5.3 5 0 0 5 5 5 5 Regulator of G protein signaling domain RGS-like PF09128.11 KDO33415.1 - 3e-06 27.1 7.1 0.019 14.7 0.3 4.1 4 0 0 4 4 4 2 Regulator of G protein signalling-like domain FA_desaturase PF00487.24 KDO33417.1 - 9.6e-27 94.4 21.1 1.4e-26 93.9 21.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KDO33417.1 - 0.0018 18.5 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) CitMHS PF03600.16 KDO33417.1 - 0.21 10.8 2.5 0.4 9.8 2.5 1.4 1 1 0 1 1 1 0 Citrate transporter Ion_trans PF00520.31 KDO33418.1 - 1.1e-154 512.7 57.5 2.1e-40 138.5 16.1 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KDO33418.1 - 6.6e-11 41.8 0.2 4.1e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KDO33418.1 - 1.9e-06 26.8 63.0 5.3e-05 22.1 0.1 9.8 8 3 3 11 11 11 7 Polycystin cation channel QueH PF02677.14 KDO33419.1 - 1.5e-56 191.2 1.7 2.7e-56 190.4 1.7 1.4 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH Thioredoxin_8 PF13905.6 KDO33420.1 - 1.2e-24 86.5 0.0 1.4e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KDO33420.1 - 1.4e-08 34.6 0.0 3.5e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KDO33420.1 - 6.2e-08 32.5 0.0 8.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 KDO33420.1 - 3.1e-06 27.6 0.0 5.8e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KDO33420.1 - 0.00011 22.2 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KDO33420.1 - 0.0024 17.6 0.0 0.15 11.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin TraF PF13728.6 KDO33420.1 - 0.0059 16.4 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KDO33420.1 - 0.016 15.4 0.1 0.054 13.7 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like DUF4472 PF14739.6 KDO33421.1 - 0.057 14.2 0.9 0.11 13.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) CENP-Q PF13094.6 KDO33421.1 - 0.095 12.9 6.4 2 8.6 6.2 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.18 KDO33421.1 - 1.7 9.0 5.7 30 4.9 0.0 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Myosin_head PF00063.21 KDO33424.1 - 7.2e-217 721.8 0.0 9e-217 721.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KDO33424.1 - 2.9e-10 39.0 33.4 0.0015 18.2 0.3 5.9 5 0 0 5 5 5 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KDO33424.1 - 0.00027 20.7 0.3 0.00055 19.7 0.3 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Rootletin PF15035.6 KDO33424.1 - 0.0059 16.6 1.6 0.012 15.6 1.6 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion POTRA_2 PF08479.11 KDO33424.1 - 0.018 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type CCDC144C PF14915.6 KDO33424.1 - 0.032 13.4 8.4 0.034 13.3 6.5 2.0 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region AAA_16 PF13191.6 KDO33424.1 - 0.085 13.2 1.2 0.29 11.5 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_6 PF12774.7 KDO33424.1 - 0.091 11.7 0.2 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region UPF0242 PF06785.11 KDO33424.1 - 0.21 11.7 4.1 0.45 10.6 4.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KDO33424.1 - 0.42 11.3 3.6 1.7 9.3 3.6 2.1 1 0 0 1 1 1 0 Initiation control protein YabA PH PF00169.29 KDO33425.1 - 6.2e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 PH domain SnoaL PF07366.12 KDO33425.1 - 3.8e-05 23.5 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PH_9 PF15410.6 KDO33425.1 - 0.019 15.3 0.0 0.081 13.3 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain DUF3287 PF11690.8 KDO33426.1 - 0.068 12.9 0.6 0.12 12.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) PSD1 PF07587.11 KDO33426.1 - 0.085 12.3 1.3 0.12 11.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1553) Cys_rich_CPXG PF14255.6 KDO33426.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG Myb_DNA-binding PF00249.31 KDO33427.1 - 1.5e-13 50.7 0.7 2.2e-13 50.1 0.7 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO33427.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KDO33427.1 - 0.0077 16.5 0.4 0.015 15.5 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain LRR_6 PF13516.6 KDO33428.1 - 2.8e-14 51.9 22.7 0.033 14.2 0.2 11.1 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 KDO33428.1 - 5.6e-08 33.0 13.7 0.33 11.4 0.8 6.8 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) IQ PF00612.27 KDO33428.1 - 0.074 12.9 0.2 0.074 12.9 0.2 16.2 15 1 1 16 16 16 0 IQ calmodulin-binding motif LRR_8 PF13855.6 KDO33428.1 - 0.12 12.2 10.1 2.1 8.2 0.2 4.1 3 2 0 3 3 3 0 Leucine rich repeat Rdx PF10262.9 KDO33430.1 - 7.1e-06 26.1 0.0 1.2e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Rdx family Rdx PF10262.9 KDO33431.1 - 1.3e-05 25.3 0.2 1.9e-05 24.7 0.2 1.5 1 1 0 1 1 1 1 Rdx family RINGv PF12906.7 KDO33432.1 - 7e-05 22.9 7.7 7e-05 22.9 7.7 2.5 3 0 0 3 3 3 1 RING-variant domain Ni_hydr_CYTB PF01292.20 KDO33432.1 - 0.055 13.1 0.9 0.81 9.3 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 ABC2_membrane_3 PF12698.7 KDO33432.1 - 0.79 8.8 5.5 1.2 8.1 5.1 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4307 PF14155.6 KDO33432.1 - 1.4 8.8 8.7 2.7 7.9 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4307) SlyX PF04102.12 KDO33438.1 - 0.0025 18.4 1.6 0.0025 18.4 1.6 3.9 3 1 0 3 3 3 1 SlyX CENP-K PF11802.8 KDO33438.1 - 0.0076 15.9 0.8 0.014 15.0 0.8 1.4 1 0 0 1 1 1 1 Centromere-associated protein K DUF812 PF05667.11 KDO33438.1 - 0.017 14.1 4.1 0.023 13.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MSA-2c PF12238.8 KDO33438.1 - 0.047 13.7 1.2 0.086 12.8 0.3 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c RasGAP_C PF03836.15 KDO33438.1 - 0.28 11.3 5.4 0.19 11.9 0.4 2.4 3 0 0 3 3 3 0 RasGAP C-terminus Antimicrobial19 PF08225.11 KDO33438.1 - 0.36 10.5 0.1 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide V_ATPase_I PF01496.19 KDO33438.1 - 0.36 8.7 0.9 0.46 8.3 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lzipper-MIP1 PF14389.6 KDO33438.1 - 0.49 10.7 9.7 0.31 11.3 4.5 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Atg14 PF10186.9 KDO33438.1 - 0.58 9.2 4.0 0.26 10.3 1.7 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KDO33438.1 - 0.77 9.8 4.8 5.5 7.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L4 PF00573.22 KDO33439.1 - 3.5e-67 225.8 1.8 4.2e-67 225.6 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family WGG PF10273.9 KDO33440.1 - 1e-19 70.9 0.1 1.8e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 CAGE1 PF15066.6 KDO33440.1 - 0.004 15.9 1.8 0.004 15.9 1.8 1.6 1 1 1 2 2 2 1 Cancer-associated gene protein 1 family DUF4061 PF13270.6 KDO33440.1 - 0.098 13.0 1.1 0.18 12.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) FAP PF07174.11 KDO33441.1 - 2.3 7.6 42.6 1.1 8.6 25.4 2.2 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) PALP PF00291.25 KDO33442.1 - 3.6e-46 157.9 2.8 4.8e-46 157.5 2.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NPCC PF08058.11 KDO33443.1 - 4.2 7.4 5.1 0.69 10.0 0.6 2.0 2 1 0 2 2 2 0 Nuclear pore complex component eRF1_2 PF03464.15 KDO33444.1 - 1.2e-43 148.7 0.0 2.2e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KDO33444.1 - 9.2e-36 122.8 0.1 2.1e-35 121.6 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KDO33444.1 - 1.3e-19 70.5 0.0 2.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KDO33444.1 - 7.8e-11 42.4 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KDO33444.1 - 9.4e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PRIMA1 PF16101.5 KDO33446.1 - 0.0052 16.8 0.3 0.0093 16.0 0.3 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 UPF0697 PF15117.6 KDO33446.1 - 0.13 12.3 0.1 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 DUF98 PF01947.16 KDO33446.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase HEAT_2 PF13646.6 KDO33447.1 - 7.1e-05 23.1 5.5 0.031 14.7 0.0 4.3 2 1 2 4 4 4 2 HEAT repeats DUF383 PF04063.14 KDO33447.1 - 9.4e-05 22.2 0.6 0.011 15.4 0.1 3.5 2 2 0 2 2 2 1 Domain of unknown function (DUF383) Arm PF00514.23 KDO33447.1 - 0.00054 19.9 10.7 0.38 10.9 0.1 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Goodbye PF17109.5 KDO33447.1 - 0.013 16.0 0.3 0.45 11.0 0.2 2.9 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Arm_2 PF04826.13 KDO33447.1 - 0.017 14.6 0.2 4.1 6.8 0.1 2.8 2 0 0 2 2 2 0 Armadillo-like HEAT_EZ PF13513.6 KDO33447.1 - 0.023 15.2 0.2 0.023 15.2 0.2 3.4 2 1 1 3 3 2 0 HEAT-like repeat RXT2_N PF08595.11 KDO33447.1 - 0.049 13.6 0.5 0.15 12.1 0.5 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal CTNNBL PF08216.11 KDO33447.1 - 0.077 13.2 0.3 0.43 10.8 0.1 2.5 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear CENP-Q PF13094.6 KDO33447.1 - 0.096 12.9 7.0 0.34 11.1 1.1 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YlbD_coat PF14071.6 KDO33447.1 - 0.21 11.8 0.3 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Putative coat protein Imm5 PF14423.6 KDO33447.1 - 0.23 11.7 3.0 46 4.2 0.0 3.5 3 0 0 3 3 3 0 Immunity protein Imm5 DUF913 PF06025.12 KDO33447.1 - 1.7 7.5 6.2 7.9 5.3 0.0 3.4 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) Cwf_Cwc_15 PF04889.12 KDO33447.1 - 2.6 7.7 12.3 0.14 11.9 1.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PHD PF00628.29 KDO33448.1 - 5.2e-10 39.1 6.5 1.1e-09 38.0 6.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KDO33448.1 - 0.00054 19.5 1.6 0.0013 18.2 1.6 1.7 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 KDO33448.1 - 0.02 15.0 6.3 0.064 13.4 6.3 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KDO33448.1 - 0.03 14.0 2.9 0.076 12.6 2.9 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-TAZ PF02135.16 KDO33448.1 - 0.55 10.7 7.7 1.7 9.1 0.2 2.9 3 0 0 3 3 3 0 TAZ zinc finger C1_2 PF03107.16 KDO33448.1 - 3.6 8.0 8.2 2.2 8.7 4.5 2.3 2 0 0 2 2 2 0 C1 domain PHD_4 PF16866.5 KDO33448.1 - 4.1 7.6 8.3 14 5.9 8.3 1.9 1 1 0 1 1 1 0 PHD-finger Presenilin PF01080.17 KDO33449.1 - 2.4e-105 352.6 1.1 4.8e-105 351.6 1.1 1.4 1 1 0 1 1 1 1 Presenilin Carn_acyltransf PF00755.20 KDO33450.1 - 1.4e-177 592.0 0.0 1.6e-177 591.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Na_H_Exchanger PF00999.21 KDO33451.1 - 2.8e-60 204.1 37.2 3.4e-60 203.8 37.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_C PF07664.12 KDO33451.1 - 0.99 9.1 4.8 2.3 8.0 0.3 3.4 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus TraL PF07178.11 KDO33451.1 - 7.7 7.1 13.9 0.62 10.6 2.2 3.8 4 0 0 4 4 4 0 TraL protein Pkinase PF00069.25 KDO33453.1 - 6.8e-64 215.8 0.0 1.2e-63 215.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33453.1 - 3.4e-33 115.0 0.0 1.2e-32 113.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 KDO33453.1 - 5.7e-12 46.1 0.4 1.7e-11 44.5 0.1 2.0 2 0 0 2 2 1 1 PH domain Ank_2 PF12796.7 KDO33453.1 - 0.00011 22.7 0.1 0.00029 21.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH_9 PF15410.6 KDO33453.1 - 0.00049 20.5 0.1 0.0017 18.7 0.0 1.9 2 0 0 2 2 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO33453.1 - 0.0011 19.4 1.0 0.0026 18.2 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_4 PF13637.6 KDO33453.1 - 0.006 17.1 0.3 0.014 16.0 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33453.1 - 0.013 16.0 0.3 0.52 11.0 0.0 3.0 3 0 0 3 3 2 0 Ankyrin repeat APH PF01636.23 KDO33453.1 - 0.017 15.0 0.4 5.1 6.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO33453.1 - 0.02 14.2 0.0 0.084 12.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KDO33453.1 - 0.035 13.7 0.1 11 5.6 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank PF00023.30 KDO33453.1 - 0.037 14.5 0.1 0.2 12.2 0.0 2.4 2 0 0 2 2 1 0 Ankyrin repeat TMF_DNA_bd PF12329.8 KDO33453.1 - 0.044 13.8 2.2 0.12 12.3 2.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PH_13 PF16652.5 KDO33453.1 - 0.059 13.2 1.3 0.084 12.7 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain TraG_N PF07916.11 KDO33453.1 - 0.07 12.0 0.3 0.11 11.4 0.3 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region NEMO PF11577.8 KDO33453.1 - 0.11 12.5 1.4 0.32 11.0 1.4 1.8 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO FAM76 PF16046.5 KDO33453.1 - 0.23 10.8 1.8 0.39 10.0 1.8 1.3 1 0 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 KDO33453.1 - 1.3 9.4 6.5 0.13 12.6 0.9 2.2 3 0 0 3 3 2 0 Csm1 N-terminal domain APS_kinase PF01583.20 KDO33454.1 - 8.9e-63 210.9 0.0 1.8e-62 209.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KDO33454.1 - 1.7e-56 191.0 0.0 3.1e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 KDO33454.1 - 2.1e-37 128.4 0.1 3.1e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 KDO33454.1 - 1.8e-32 112.2 0.0 9.1e-32 109.9 0.0 2.2 2 1 0 2 2 2 1 PUA-like domain AAA_33 PF13671.6 KDO33454.1 - 1.8e-06 28.1 0.0 6.7e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KDO33454.1 - 0.0036 17.8 0.1 0.013 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KDO33454.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KDO33454.1 - 0.025 14.3 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 KDO33454.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF815 PF05673.13 KDO33454.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KDO33454.1 - 0.085 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Myb_DNA-binding PF00249.31 KDO33455.1 - 6.2e-33 112.7 8.4 9.9e-18 64.1 1.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO33455.1 - 1.6e-22 79.5 8.1 2.1e-14 53.5 0.7 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KDO33455.1 - 3.1e-06 27.2 0.2 0.0071 16.4 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 KDO33455.1 - 6e-06 26.1 2.0 1.1e-05 25.3 0.3 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KDO33455.1 - 9.8e-05 22.7 7.7 0.00064 20.0 1.1 2.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KDO33455.1 - 0.083 13.1 0.9 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 KDO33455.1 - 0.15 12.2 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_5 PF13873.6 KDO33455.1 - 1.1 9.3 5.6 1.3 9.1 0.3 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KDO33456.1 - 1.2e-23 83.0 1.0 2.2e-23 82.2 1.0 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KDO33456.1 - 8.7e-11 42.0 0.8 3.1e-10 40.2 0.8 1.9 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) tRNA-synt_1c PF00749.21 KDO33456.1 - 0.077 11.9 0.2 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Myb_DNA-bind_6 PF13921.6 KDO33456.1 - 0.11 12.7 0.2 0.29 11.4 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KDO33456.1 - 0.12 12.6 0.2 0.25 11.5 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRM_1 PF00076.22 KDO33457.1 - 2.6e-17 62.4 0.0 5.4e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKA1 PF07160.12 KDO33457.1 - 0.00033 20.6 2.0 0.00038 20.4 2.0 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 YabA PF06156.13 KDO33457.1 - 0.0026 18.4 1.6 0.0035 17.9 1.6 1.2 1 0 0 1 1 1 1 Initiation control protein YabA Spectrin PF00435.21 KDO33457.1 - 0.0087 16.5 5.9 0.16 12.4 5.4 2.1 1 1 1 2 2 2 1 Spectrin repeat RRM_5 PF13893.6 KDO33457.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fib_alpha PF08702.10 KDO33457.1 - 0.02 15.0 1.0 0.026 14.7 1.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.6 KDO33457.1 - 0.025 14.8 2.3 0.034 14.4 2.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.9 KDO33457.1 - 0.031 14.6 2.7 0.067 13.5 2.7 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Methyltransf_29 PF03141.16 KDO33457.1 - 0.032 12.8 0.0 0.038 12.5 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2046 PF09755.9 KDO33457.1 - 0.039 13.2 3.1 0.057 12.6 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Prefoldin_2 PF01920.20 KDO33457.1 - 0.042 13.8 4.1 0.073 13.0 4.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF3220 PF11516.8 KDO33457.1 - 0.047 13.9 0.5 0.074 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) DUF465 PF04325.13 KDO33457.1 - 0.061 13.4 1.6 0.1 12.7 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF465) CENP-F_leu_zip PF10473.9 KDO33457.1 - 0.064 13.3 6.0 0.091 12.8 6.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 KDO33457.1 - 0.076 13.3 4.7 0.12 12.6 4.7 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 GPS2_interact PF15784.5 KDO33457.1 - 0.092 13.2 2.3 0.16 12.4 2.3 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TMPIT PF07851.13 KDO33457.1 - 0.098 11.9 1.1 0.12 11.6 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KDO33457.1 - 0.1 10.5 2.1 0.12 10.2 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KDO33457.1 - 0.12 11.2 3.8 0.14 11.0 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4988 PF16378.5 KDO33457.1 - 0.12 12.0 0.7 0.2 11.3 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function DASH_Spc19 PF08287.11 KDO33457.1 - 0.15 12.0 2.0 0.19 11.6 2.0 1.1 1 0 0 1 1 1 0 Spc19 Spc24 PF08286.11 KDO33457.1 - 0.21 11.9 1.9 0.3 11.3 1.9 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 KDO33457.1 - 0.22 11.3 3.3 0.3 10.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 KDO33457.1 - 0.29 11.7 6.1 0.44 11.1 6.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region CLZ PF16526.5 KDO33457.1 - 0.32 11.4 3.8 0.62 10.5 3.8 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Csm1_N PF18504.1 KDO33457.1 - 0.68 10.3 7.0 1.4 9.3 6.8 1.5 2 0 0 2 2 1 0 Csm1 N-terminal domain HAUS6_N PF14661.6 KDO33457.1 - 0.69 9.5 3.2 0.95 9.0 3.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1664 PF07889.12 KDO33457.1 - 0.86 9.7 3.6 1.4 8.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KDO33457.1 - 1.4 8.7 5.2 2.5 7.9 5.2 1.5 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 KDO33457.1 - 1.5 9.3 5.0 3 8.3 5.0 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) GAT PF03127.14 KDO33458.1 - 0.053 13.8 1.2 0.23 11.8 0.3 2.2 2 0 0 2 2 2 0 GAT domain UPF0160 PF03690.13 KDO33460.1 - 1e-125 419.6 0.0 1.1e-125 419.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) TPR_5 PF12688.7 KDO33461.1 - 0.0022 18.2 4.1 0.008 16.4 4.1 2.0 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_16 PF13432.6 KDO33461.1 - 0.028 15.1 3.8 0.028 15.1 3.8 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3361 PF11841.8 KDO33461.1 - 0.029 14.3 0.1 0.075 13.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) TPR_19 PF14559.6 KDO33461.1 - 0.033 14.7 0.6 0.033 14.7 0.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.6 KDO33461.1 - 0.66 10.3 3.8 0.96 9.8 2.4 2.1 1 1 1 2 2 2 0 AAA ATPase domain Myb_DNA-binding PF00249.31 KDO33462.1 - 5.7e-09 36.0 0.0 0.00036 20.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO33462.1 - 9.6e-07 29.0 0.0 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KDO33462.1 - 0.02 15.0 0.7 14 5.9 0.1 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2232 PF09991.9 KDO33462.1 - 3.8 6.6 5.0 6.4 5.9 5.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) ABC2_membrane PF01061.24 KDO33464.1 - 8.4e-32 110.3 21.1 1.4e-31 109.6 21.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO33464.1 - 3.1e-28 99.0 0.0 8e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 KDO33464.1 - 1.5e-06 28.0 0.5 0.011 15.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KDO33464.1 - 1.9e-06 27.5 1.1 0.0029 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KDO33464.1 - 3.2e-06 27.6 0.1 0.021 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KDO33464.1 - 1.1e-05 25.7 0.1 0.046 14.0 0.1 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KDO33464.1 - 2e-05 24.6 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KDO33464.1 - 9.3e-05 22.2 1.6 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KDO33464.1 - 0.00027 21.1 3.2 0.33 11.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 KDO33464.1 - 0.00047 20.2 0.3 0.97 9.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KDO33464.1 - 0.00069 20.1 0.1 0.038 14.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KDO33464.1 - 0.0011 19.5 0.1 0.87 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KDO33464.1 - 0.0026 17.7 0.7 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.6 KDO33464.1 - 0.0035 17.1 1.6 2.1 8.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KDO33464.1 - 0.0053 17.1 1.1 0.11 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KDO33464.1 - 0.0064 17.0 1.5 0.87 10.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KDO33464.1 - 0.014 15.7 0.2 5.5 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 KDO33464.1 - 0.015 14.9 2.4 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KDO33464.1 - 0.015 15.1 0.4 4.7 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KDO33464.1 - 0.019 14.1 18.8 0.074 12.1 17.7 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_17 PF13207.6 KDO33464.1 - 0.021 15.3 0.8 0.18 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KDO33464.1 - 0.035 13.4 0.1 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 KDO33464.1 - 0.045 14.0 0.7 13 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KDO33464.1 - 0.053 13.0 0.7 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 KDO33464.1 - 0.079 12.2 1.3 3.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 KDO33464.1 - 0.08 12.4 0.0 20 4.5 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KDO33464.1 - 0.11 12.0 3.0 12 5.4 0.0 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KDO33464.1 - 0.18 11.5 0.7 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 KDO33464.1 - 0.19 11.4 0.0 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 KDO33464.1 - 0.2 11.8 0.5 19 5.4 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase UvrD-helicase PF00580.21 KDO33464.1 - 0.28 10.6 1.1 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF4050 PF13259.6 KDO33464.1 - 0.3 11.4 5.2 0.55 10.5 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) MobB PF03205.14 KDO33464.1 - 0.46 10.4 1.4 16 5.4 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TMPIT PF07851.13 KDO33464.1 - 0.59 9.3 4.6 1.2 8.3 4.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein NACHT PF05729.12 KDO33464.1 - 0.62 10.0 9.2 1.7 8.5 0.0 3.6 4 0 0 4 4 3 0 NACHT domain DUF87 PF01935.17 KDO33464.1 - 1.3 9.1 5.5 20 5.2 0.2 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain LRR_8 PF13855.6 KDO33465.1 - 4.5e-20 71.2 23.7 1.5e-09 37.4 1.7 4.7 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KDO33465.1 - 7.9e-13 48.4 20.2 3.8e-05 24.0 1.3 5.3 1 1 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO33465.1 - 0.0064 16.9 12.7 1.2 9.9 0.6 5.6 5 1 0 5 5 5 1 Leucine Rich Repeat XFP PF03894.15 KDO33465.1 - 0.1 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TFIIA PF03153.13 KDO33465.1 - 0.13 12.2 23.8 0.24 11.4 23.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KDO33465.1 - 0.15 11.4 24.0 0.28 10.5 24.0 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KDO33465.1 - 1.2 7.3 23.7 1.9 6.6 23.7 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KDO33465.1 - 3 6.3 12.4 5 5.6 12.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5320 PF17253.2 KDO33465.1 - 3.2 8.9 4.2 68 4.6 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) PPP4R2 PF09184.11 KDO33465.1 - 5.4 6.5 16.1 13 5.3 16.1 1.7 1 0 0 1 1 1 0 PPP4R2 AAA PF00004.29 KDO33466.1 - 7.9e-20 71.6 0.0 2.2e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KDO33466.1 - 4.9e-05 23.4 0.0 0.00025 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KDO33466.1 - 9.8e-05 22.6 0.0 0.0062 16.8 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KDO33466.1 - 0.0039 17.2 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KDO33466.1 - 0.0044 17.4 0.0 0.028 14.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO33466.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KDO33466.1 - 0.011 15.0 0.1 0.021 14.0 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KDO33466.1 - 0.012 15.5 0.3 0.81 9.5 0.0 3.1 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KDO33466.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KDO33466.1 - 0.024 14.0 0.0 0.47 9.8 0.0 2.6 1 1 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 KDO33466.1 - 0.025 14.7 0.2 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KDO33466.1 - 0.027 14.6 0.0 0.097 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KDO33466.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KDO33466.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zot PF05707.12 KDO33466.1 - 0.11 12.1 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.22 KDO33466.1 - 0.13 12.6 0.0 0.72 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KDO33466.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KDO33466.1 - 0.55 9.8 3.1 3.3 7.3 0.1 3.3 3 1 0 4 4 4 0 AAA domain RNA_pol_Rpc4 PF05132.14 KDO33466.1 - 2.2 8.7 10.4 2.2 8.7 2.4 2.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pkinase PF00069.25 KDO33468.1 - 1.8e-70 237.3 0.0 2.4e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33468.1 - 7.4e-38 130.3 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO33468.1 - 6.4e-06 25.2 0.4 1.3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KDO33468.1 - 0.00018 20.9 0.0 0.00048 19.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like POLO_box PF00659.18 KDO33468.1 - 0.0039 17.4 0.0 0.0089 16.2 0.0 1.6 1 0 0 1 1 1 1 POLO box duplicated region APH PF01636.23 KDO33468.1 - 0.0063 16.5 0.3 0.016 15.2 0.3 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 KDO33468.1 - 0.015 15.4 0.1 0.062 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC1 family RIO1 PF01163.22 KDO33468.1 - 0.022 14.3 0.2 0.057 13.0 0.2 1.7 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 KDO33468.1 - 0.06 12.7 1.2 0.092 12.1 0.0 1.8 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 KDO33469.1 - 1.3e-14 53.8 0.1 1.8e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO33469.1 - 2.9e-05 23.7 0.0 4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO33469.1 - 0.00062 19.6 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Pkinase PF00069.25 KDO33471.1 - 3.3e-45 154.5 0.0 5.1e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33471.1 - 2.3e-42 145.1 0.0 4e-42 144.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO33471.1 - 6.7e-06 26.6 0.3 4.3e-05 24.0 0.0 2.5 3 0 0 3 3 3 1 PH domain Pkinase_fungal PF17667.1 KDO33471.1 - 7.3e-05 21.7 0.1 0.00012 21.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase SAM_1 PF00536.30 KDO33471.1 - 0.0013 19.2 0.0 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 KDO33471.1 - 0.0039 16.2 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain SAM_2 PF07647.17 KDO33471.1 - 0.0043 17.1 0.0 0.046 13.8 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) APH PF01636.23 KDO33471.1 - 0.0049 16.8 1.3 0.021 14.8 0.2 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family BCL_N PF04714.13 KDO33471.1 - 0.029 14.4 0.3 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Kinase-like PF14531.6 KDO33471.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Actin PF00022.19 KDO33472.1 - 2.6e-22 79.0 0.0 1e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Actin OSCP PF00213.18 KDO33474.1 - 7.1e-45 153.2 1.5 8.4e-45 153.0 1.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit RNase_PH PF01138.21 KDO33475.1 - 1.3e-17 64.5 0.1 3.4e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KDO33475.1 - 2.2e-08 34.0 0.1 6.1e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF812 PF05667.11 KDO33476.1 - 8.3e-90 302.4 11.9 5e-60 204.0 14.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF812) HALZ PF02183.18 KDO33476.1 - 0.012 15.8 0.3 0.36 11.1 0.1 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 KDO33476.1 - 1.7 9.1 15.4 0.1 13.1 2.6 4.0 3 1 0 3 3 3 0 Cell division protein ZapB FA_desaturase PF00487.24 KDO33477.1 - 1e-12 48.5 24.0 3.9e-12 46.6 24.0 1.9 1 1 0 1 1 1 1 Fatty acid desaturase Sec3_C PF09763.9 KDO33478.1 - 4.8e-26 91.4 0.0 3.1e-14 52.3 0.0 3.5 2 1 0 2 2 2 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KDO33478.1 - 0.00076 19.6 0.0 0.0039 17.3 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH TetR_C_30 PF17939.1 KDO33478.1 - 0.031 14.5 4.1 41 4.4 0.0 4.6 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L4 PF00573.22 KDO33479.1 - 1.5e-41 142.2 0.5 3e-41 141.2 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KDO33479.1 - 1.4e-27 95.5 3.0 2.3e-27 94.8 1.1 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Prefoldin_2 PF01920.20 KDO33479.1 - 0.015 15.3 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit DENN PF02141.21 KDO33480.1 - 6.7e-09 36.0 3.8 6.7e-09 36.0 3.8 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain TPR_1 PF00515.28 KDO33480.1 - 0.019 14.7 0.2 0.86 9.5 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33480.1 - 0.058 13.5 4.2 10 6.5 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33480.1 - 0.14 12.5 16.8 2.7 8.4 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33480.1 - 2.3 9.3 5.4 45 5.2 0.4 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33480.1 - 6.2 7.1 9.4 8.1 6.7 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NAC PF01849.18 KDO33481.1 - 2.2e-23 82.0 0.8 5e-23 80.8 0.8 1.6 1 0 0 1 1 1 1 NAC domain Augurin PF15187.6 KDO33481.1 - 1.2 9.4 7.0 2.4 8.3 0.0 2.7 1 1 0 2 2 2 0 Oesophageal cancer-related gene 4 PBP1_TM PF14812.6 KDO33481.1 - 9.4 6.7 8.8 4.2 7.8 5.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L26 PF16906.5 KDO33482.1 - 9.6e-28 96.5 0.9 1.3e-27 96.1 0.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KDO33482.1 - 3.8e-06 26.6 1.6 3.8e-06 26.6 1.6 2.1 2 1 0 2 2 2 1 KOW motif VEG PF06257.11 KDO33482.1 - 0.14 12.2 2.2 0.43 10.6 0.2 2.2 2 0 0 2 2 2 0 Biofilm formation stimulator VEG MFS_1 PF07690.16 KDO33483.1 - 3.3e-33 115.1 36.7 3.3e-33 115.1 36.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO33483.1 - 1.5e-20 73.1 20.0 6.4e-11 41.3 3.7 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO33483.1 - 1.1e-12 47.6 7.9 1.1e-12 47.6 7.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter dsrm PF00035.26 KDO33484.1 - 6.2e-16 58.9 0.1 3.4e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif TPR_2 PF07719.17 KDO33484.1 - 6.6e-05 22.7 2.9 0.00013 21.8 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33484.1 - 0.0001 22.0 0.3 0.0001 22.0 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO33484.1 - 0.0013 18.8 0.8 0.004 17.3 0.8 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat LPP20 PF02169.16 KDO33484.1 - 0.02 15.2 0.1 0.075 13.4 0.1 1.9 1 0 0 1 1 1 0 LPP20 lipoprotein TPR_14 PF13428.6 KDO33484.1 - 0.051 14.4 0.3 0.051 14.4 0.3 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33484.1 - 0.17 11.6 1.0 12 5.7 0.0 2.9 3 0 0 3 3 3 0 TPR repeat HSP70 PF00012.20 KDO33486.1 - 1.4e-244 812.8 12.3 1.1e-243 809.9 12.3 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO33486.1 - 3.4e-13 49.1 3.3 5.8e-11 41.8 0.0 3.1 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 KDO33486.1 - 0.0078 16.6 7.5 2.3 8.7 0.0 4.1 3 3 0 3 3 3 2 Cell division protein FtsA Peptidase_M24 PF00557.24 KDO33487.1 - 3.9e-50 170.5 0.0 5.5e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PrmA PF06325.13 KDO33489.1 - 7.5e-13 48.5 0.1 1.3e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO33489.1 - 5e-10 39.9 0.0 3e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO33489.1 - 1.4e-09 38.5 0.0 8.9e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KDO33489.1 - 8e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KDO33489.1 - 1.9e-07 31.0 0.0 3.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO33489.1 - 3.7e-06 26.9 0.0 6.3e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KDO33489.1 - 5.3e-06 25.6 0.0 8.5e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.16 KDO33489.1 - 8.5e-06 25.7 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.14 KDO33489.1 - 1e-05 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 KDO33489.1 - 1.7e-05 24.6 0.1 4e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KDO33489.1 - 5.8e-05 23.1 0.1 0.0001 22.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KDO33489.1 - 0.00014 21.7 0.1 0.00023 21.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein GidB PF02527.15 KDO33489.1 - 0.004 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 KDO33489.1 - 0.0044 17.7 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO33489.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KDO33489.1 - 0.01 16.9 0.0 0.021 15.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KDO33489.1 - 0.028 14.1 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Rsm22 PF09243.10 KDO33489.1 - 0.035 13.4 0.2 0.055 12.7 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.20 KDO33489.1 - 0.056 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KDO33489.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fra10Ac1 PF09725.9 KDO33490.1 - 1.1e-44 151.5 1.5 1.6e-44 151.0 1.5 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 APG6_N PF17675.1 KDO33491.1 - 0.0095 16.5 13.9 0.0095 16.5 13.9 4.1 1 1 2 3 3 2 1 Apg6 coiled-coil region DUF1542 PF07564.11 KDO33491.1 - 0.017 15.3 0.7 0.017 15.3 0.7 3.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) GIT_CC PF16559.5 KDO33491.1 - 0.034 14.0 0.2 0.034 14.0 0.2 5.3 4 2 2 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KDO33491.1 - 0.035 14.3 1.3 0.035 14.3 1.3 5.8 2 2 3 5 5 5 0 Centrosomin N-terminal motif 1 GAS PF13851.6 KDO33491.1 - 0.05 12.9 36.2 0.081 12.3 7.0 3.5 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Phlebovirus_NSM PF07246.11 KDO33491.1 - 0.053 12.9 11.7 0.012 15.1 4.5 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF1843 PF08898.10 KDO33491.1 - 0.064 13.8 8.2 0.13 12.7 0.3 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) H-kinase_dim PF02895.14 KDO33491.1 - 0.067 13.6 0.3 0.067 13.6 0.3 3.6 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain bZIP_2 PF07716.15 KDO33491.1 - 0.073 13.2 31.3 0.26 11.4 0.6 6.7 5 2 2 7 7 7 0 Basic region leucine zipper Gly_acyl_tr_C PF08444.10 KDO33491.1 - 0.12 12.6 0.9 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region WD40_alt PF14077.6 KDO33491.1 - 0.12 12.2 2.5 5.5 6.9 0.4 3.7 3 0 0 3 3 3 0 Alternative WD40 repeat motif KASH_CCD PF14662.6 KDO33491.1 - 0.24 11.2 34.5 0.02 14.7 7.4 3.7 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH ABC_tran_CTD PF16326.5 KDO33491.1 - 0.35 11.2 29.5 0.1 12.9 1.3 5.0 2 2 2 4 4 4 0 ABC transporter C-terminal domain PRKG1_interact PF15898.5 KDO33491.1 - 0.35 11.8 32.2 0.47 11.4 5.2 4.0 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 KDO33491.1 - 0.41 10.7 32.4 0.059 13.4 1.3 4.3 3 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Shugoshin_N PF07558.11 KDO33491.1 - 0.49 10.3 11.4 32 4.5 0.3 5.0 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region NEMO PF11577.8 KDO33491.1 - 0.52 10.4 14.7 5.6 7.1 0.2 4.3 4 0 0 4 4 4 0 NF-kappa-B essential modulator NEMO DUF3450 PF11932.8 KDO33491.1 - 1 8.6 28.3 1.5 8.1 1.6 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 KDO33491.1 - 2.2 8.5 36.0 3.5 7.9 1.0 5.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Rota_NSP4 PF01452.16 KDO33491.1 - 3.3 7.3 7.0 1.6 8.4 1.1 2.7 2 1 1 3 3 3 0 Rotavirus non structural protein CPSase_L_D3 PF02787.19 KDO33491.1 - 3.4 8.0 7.5 0.58 10.5 2.3 2.4 1 1 1 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Spc7 PF08317.11 KDO33491.1 - 4.2 6.2 34.8 0.024 13.5 13.6 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein CP12 PF02672.15 KDO33491.1 - 4.2 8.2 16.8 9.6 7.0 0.1 5.2 3 2 2 5 5 5 0 CP12 domain DUF465 PF04325.13 KDO33491.1 - 4.7 7.3 16.7 4.7 7.3 0.2 5.6 4 1 2 6 6 6 0 Protein of unknown function (DUF465) ATG16 PF08614.11 KDO33491.1 - 4.8 7.4 40.5 0.1 12.8 6.5 3.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 KDO33491.1 - 5.1 6.2 35.5 1.2 8.3 22.3 3.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region SOGA PF11365.8 KDO33491.1 - 5.2 8.3 24.8 4.7 8.4 2.3 4.7 3 2 1 4 4 4 0 Protein SOGA HIP1_clath_bdg PF16515.5 KDO33491.1 - 8.5 7.1 39.6 0.21 12.2 2.0 5.3 1 1 5 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Methyltransf_8 PF05148.15 KDO33492.1 - 1.7e-78 263.5 0.0 2e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KDO33492.1 - 2e-06 28.3 0.0 1.9e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33492.1 - 0.00096 19.8 0.0 0.077 13.7 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33492.1 - 0.059 13.2 0.0 0.89 9.3 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Adap_comp_sub PF00928.21 KDO33493.1 - 1.5e-85 286.8 0.0 1.9e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 KDO33493.1 - 4.8e-06 26.2 0.1 7.5e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain Peptidase_C24 PF03510.14 KDO33493.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family Pkinase PF00069.25 KDO33495.1 - 2.9e-25 89.1 0.0 4.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33495.1 - 2.7e-17 62.9 0.0 3.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO33495.1 - 3.1e-09 36.6 0.0 4.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO33495.1 - 0.0004 19.8 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BT1 PF03092.16 KDO33496.1 - 3e-12 45.6 8.1 1.6e-11 43.1 1.9 2.5 2 0 0 2 2 2 2 BT1 family EGF_2 PF07974.13 KDO33497.1 - 1.8e-21 76.2 120.2 4.2e-06 27.0 3.7 10.4 11 0 0 11 11 11 8 EGF-like domain DSPc PF00782.20 KDO33498.1 - 1.9e-27 95.7 0.0 2.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO33498.1 - 0.0053 16.3 0.0 0.0096 15.5 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KDO33498.1 - 0.0057 16.9 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KDO33498.1 - 0.1 12.6 0.0 0.26 11.2 0.1 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Myb_DNA-binding PF00249.31 KDO33499.1 - 1.2e-40 137.5 10.2 3.4e-15 56.0 0.5 4.2 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO33499.1 - 2.4e-36 123.8 3.1 1.2e-15 57.5 0.2 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain MMR_HSR1 PF01926.23 KDO33499.1 - 4e-07 30.1 0.0 7.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO33499.1 - 6.1e-05 23.5 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KDO33499.1 - 0.00011 22.7 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Myb_DNA-bind_4 PF13837.6 KDO33499.1 - 0.00034 20.9 2.2 5.7 7.4 0.0 3.6 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain RsgA_GTPase PF03193.16 KDO33499.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KDO33499.1 - 0.0019 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KDO33499.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 KDO33499.1 - 0.003 16.7 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MADF_DNA_bdg PF10545.9 KDO33499.1 - 0.003 17.8 0.9 1.5 9.2 0.0 3.3 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_22 PF13401.6 KDO33499.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO33499.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rap1_C PF11626.8 KDO33499.1 - 0.06 13.4 1.3 1.3 9.2 0.7 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Dynamin_N PF00350.23 KDO33499.1 - 0.096 12.7 0.1 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Dynamin family SLIDE PF09111.10 KDO33499.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 SLIDE AAA_5 PF07728.14 KDO33499.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KDO33499.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Mannosyl_trans3 PF11051.8 KDO33500.1 - 1.7e-31 109.6 0.0 1.6e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Mannosyltransferase putative TBPIP PF07106.13 KDO33502.1 - 5.3e-24 83.9 1.5 1.1e-23 82.9 0.8 2.0 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 KDO33502.1 - 1.6e-10 40.9 0.8 1.6e-10 40.9 0.8 2.6 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 KDO33502.1 - 0.00012 22.4 2.1 0.00035 20.9 0.8 2.3 1 1 1 2 2 2 1 Penicillinase repressor MscS_porin PF12795.7 KDO33502.1 - 0.0012 18.5 2.1 0.0026 17.4 2.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain PilJ PF13675.6 KDO33502.1 - 0.0022 18.0 1.3 0.0055 16.7 0.9 1.9 1 1 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term Phlebovirus_NSM PF07246.11 KDO33502.1 - 0.0094 15.4 0.4 0.0094 15.4 0.4 1.5 2 0 0 2 2 2 1 Phlebovirus nonstructural protein NS-M Nsp1_C PF05064.13 KDO33502.1 - 0.035 13.9 0.3 0.074 12.9 0.3 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region GCP_N_terminal PF17681.1 KDO33502.1 - 0.037 13.6 0.1 0.068 12.8 0.1 1.4 1 1 0 1 1 1 0 Gamma tubulin complex component N-terminal Fusion_gly PF00523.18 KDO33502.1 - 0.06 11.6 0.0 0.086 11.1 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 ATP-synt_DE PF00401.20 KDO33502.1 - 0.11 12.8 0.4 0.11 12.8 0.4 2.2 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF2730 PF10805.8 KDO33502.1 - 0.13 12.3 0.5 0.29 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) eIF3_subunit PF08597.10 KDO33502.1 - 3.7 7.4 29.4 0.025 14.5 20.5 1.9 2 1 0 2 2 2 0 Translation initiation factor eIF3 subunit Hid1 PF12722.7 KDO33502.1 - 4.2 5.4 6.4 6.1 4.8 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4355 PF14265.6 KDO33502.1 - 4.4 7.6 14.7 0.26 11.5 7.3 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4355) Prefoldin_2 PF01920.20 KDO33502.1 - 5.2 7.1 9.1 1 9.4 0.3 3.2 2 2 2 4 4 4 0 Prefoldin subunit Pkinase PF00069.25 KDO33503.1 - 3.6e-46 157.7 0.0 5.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33503.1 - 9.9e-46 156.1 0.0 1.6e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KDO33503.1 - 6.5e-12 45.0 24.8 1.2e-07 31.4 3.0 4.8 1 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KDO33503.1 - 3e-06 27.5 18.0 0.017 15.5 0.3 5.2 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO33503.1 - 1.9e-05 24.3 9.5 0.00074 19.1 2.6 2.9 1 1 3 4 4 4 3 Leucine-rich repeat Pkinase_fungal PF17667.1 KDO33503.1 - 0.00014 20.8 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO33503.1 - 0.00051 19.5 0.0 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KDO33503.1 - 0.086 12.8 0.2 0.36 10.7 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KDO33504.1 - 5.5e-07 29.2 0.0 7.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33504.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase LRR_4 PF12799.7 KDO33505.1 - 0.029 14.8 0.9 0.093 13.2 0.9 2.0 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KDO33506.1 - 2.5e-46 158.2 0.0 1.4e-45 155.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33506.1 - 1.6e-43 148.9 0.0 2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO33506.1 - 1.1e-06 28.8 1.8 0.18 12.2 0.1 4.2 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO33506.1 - 0.00015 21.4 0.3 0.044 13.5 0.0 2.8 2 0 0 2 2 2 2 Leucine rich repeat Pkinase_fungal PF17667.1 KDO33506.1 - 0.00016 20.6 0.0 0.00021 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 KDO33506.1 - 0.00064 19.6 0.1 6.9 7.0 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich repeat Pkinase_Tyr PF07714.17 KDO33508.1 - 2.1e-42 145.2 0.0 3.4e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO33508.1 - 3.1e-40 138.2 0.0 1e-39 136.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KDO33508.1 - 4.8e-09 35.8 0.5 0.00023 20.9 0.1 3.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KDO33508.1 - 1.7e-07 31.4 0.1 0.29 11.6 0.0 4.5 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) WD40 PF00400.32 KDO33510.1 - 1.3e-63 209.4 23.6 8.9e-08 32.7 0.0 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.11 KDO33510.1 - 1.7e-37 128.5 0.0 3.5e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KDO33510.1 - 8.9e-23 80.4 5.9 0.0014 18.9 0.0 7.8 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO33510.1 - 3.6e-10 39.1 13.5 0.0073 15.0 0.0 6.8 4 3 3 8 8 8 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KDO33510.1 - 1.4e-07 30.6 0.7 0.48 9.1 0.0 4.9 2 2 1 5 5 5 3 Nup133 N terminal like Ge1_WD40 PF16529.5 KDO33510.1 - 1.5e-07 30.7 11.9 0.41 9.6 0.0 6.5 3 3 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KDO33510.1 - 7.7e-07 28.0 1.1 0.021 13.4 0.1 2.9 2 1 1 3 3 3 3 Cytochrome D1 heme domain WD40_like PF17005.5 KDO33510.1 - 2.3e-06 27.2 0.0 0.089 12.1 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 KDO33510.1 - 5e-06 26.5 0.2 0.65 9.8 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A nos_propeller PF18764.1 KDO33510.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat PALB2_WD40 PF16756.5 KDO33510.1 - 0.069 12.1 5.0 1.7 7.4 0.6 3.7 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DUF2025 PF09634.10 KDO33510.1 - 0.17 11.9 0.1 16 5.5 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2025) Disintegrin PF00200.23 KDO33511.1 - 2.1e-20 73.3 79.2 0.00012 22.8 12.1 7.6 5 3 1 6 6 6 6 Disintegrin MtrB PF05440.12 KDO33511.1 - 7.1 7.1 5.6 31 5.1 0.4 3.1 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B TAN PF11640.8 KDO33513.1 - 0.046 13.8 0.9 0.063 13.4 0.9 1.1 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Ribosomal_S19e PF01090.19 KDO33513.1 - 0.057 13.1 0.7 0.082 12.6 0.5 1.5 1 1 0 1 1 1 0 Ribosomal protein S19e Glycos_transf_1 PF00534.20 KDO33514.1 - 0.0001 21.9 0.0 0.00028 20.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO33514.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_hydro_38N PF01074.22 KDO33515.1 - 5.9e-79 265.4 7.4 8.2e-79 265.0 7.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KDO33515.1 - 2.4e-32 112.7 0.0 3.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KDO33515.1 - 3.4e-18 65.6 0.1 7.3e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KDO33515.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glycos_transf_1 PF00534.20 KDO33516.1 - 6.7e-05 22.5 0.0 0.00015 21.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO33516.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Aida_C2 PF14186.6 KDO33517.1 - 7.2e-43 145.7 0.0 1.4e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 KDO33517.1 - 3.2e-23 82.1 0.0 5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Aida N-terminus Adaptin_N PF01602.20 KDO33518.1 - 2.8e-110 369.4 13.0 3.8e-110 368.9 13.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KDO33518.1 - 3e-47 160.5 0.1 1e-46 158.8 0.1 1.9 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KDO33518.1 - 1.6e-30 105.5 0.0 3.7e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KDO33518.1 - 2.8e-15 56.4 5.5 2.6e-06 27.7 0.0 6.3 3 2 3 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KDO33518.1 - 6.2e-14 52.4 14.7 3.3e-08 33.7 1.3 4.2 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO33518.1 - 0.0011 19.4 4.2 2.9 8.5 0.7 4.9 3 1 2 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KDO33518.1 - 0.0061 16.7 12.9 13 6.4 0.0 7.5 8 0 0 8 8 8 1 HEAT repeat Arm PF00514.23 KDO33518.1 - 0.0069 16.4 0.1 10 6.3 0.0 5.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ATPase PF06745.13 KDO33518.1 - 0.068 12.5 0.0 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 KaiC DUF4197 PF13852.6 KDO33518.1 - 0.099 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Prp18 PF02840.15 KDO33519.1 - 1.4e-58 197.0 1.2 3e-58 195.9 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KDO33519.1 - 1.6e-11 43.5 1.5 3.7e-11 42.4 1.5 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like SHIPPO-rpt PF07004.12 KDO33519.1 - 0.0082 17.0 5.7 4.9 8.2 0.0 3.8 3 0 0 3 3 3 2 Sperm-tail PG-rich repeat Pex14_N PF04695.13 KDO33519.1 - 0.037 14.7 3.0 0.13 13.0 3.0 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-CCHC PF00098.23 KDO33520.1 - 2e-14 52.9 38.5 0.00019 21.4 0.2 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 KDO33520.1 - 0.0012 18.7 2.9 0.053 13.4 0.1 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 KDO33520.1 - 0.029 14.1 31.0 0.28 11.0 1.0 5.1 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_6 PF15288.6 KDO33520.1 - 0.029 14.2 0.5 0.029 14.2 0.5 4.4 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_3 PF13917.6 KDO33520.1 - 2.9 7.9 23.6 4.2 7.4 0.4 4.5 2 1 2 4 4 4 0 Zinc knuckle TPR_2 PF07719.17 KDO33521.1 - 0.0092 16.0 0.6 0.48 10.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33521.1 - 0.022 15.4 1.3 0.074 13.7 1.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO33521.1 - 0.23 11.7 1.1 0.53 10.6 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 XkdW PF09636.10 KDO33522.1 - 0.0029 17.7 0.4 0.0093 16.0 0.1 2.1 1 1 1 2 2 2 1 XkdW protein BBP1_C PF15272.6 KDO33522.1 - 0.0055 16.5 5.8 0.0055 16.5 5.8 1.9 1 1 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Nsp1_C PF05064.13 KDO33522.1 - 0.0056 16.5 3.1 0.11 12.3 0.0 2.9 3 1 0 3 3 3 1 Nsp1-like C-terminal region DUF16 PF01519.16 KDO33522.1 - 0.009 16.5 0.2 0.009 16.5 0.2 3.1 2 1 2 4 4 4 1 Protein of unknown function DUF16 Atg14 PF10186.9 KDO33522.1 - 0.19 10.8 15.3 0.088 11.9 2.4 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KDO33522.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KDO33522.1 - 0.36 11.2 2.4 31 5.1 0.1 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KDO33522.1 - 0.61 10.3 12.0 2.2 8.5 4.1 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KDO33522.1 - 0.86 9.5 5.3 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KDO33522.1 - 6.5 7.5 10.0 5.5 7.7 0.1 3.4 1 1 2 3 3 3 0 Initiation control protein YabA Ank_2 PF12796.7 KDO33523.1 - 1.5e-50 169.7 11.0 2.4e-15 56.9 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33523.1 - 1.2e-37 127.7 7.3 1.2e-07 32.1 0.2 7.9 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33523.1 - 1.5e-37 123.3 18.9 0.00035 20.8 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KDO33523.1 - 1.2e-34 117.9 14.5 8.5e-07 29.1 0.4 8.6 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO33523.1 - 1.2e-31 107.7 22.7 5.6e-05 23.4 0.2 10.9 10 1 0 10 10 10 9 Ankyrin repeat APOBEC4 PF18775.1 KDO33523.1 - 0.037 14.2 0.1 20 5.4 0.0 3.7 3 0 0 3 3 3 0 APOBEC4 Nop10p PF04135.12 KDO33524.1 - 2.1e-21 75.7 0.7 3e-21 75.2 0.7 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ras PF00071.22 KDO33525.1 - 1.1e-48 164.9 0.0 1.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO33525.1 - 8.9e-30 103.4 0.0 2.2e-29 102.1 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO33525.1 - 3e-10 39.8 0.0 3.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO33525.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KDO33525.1 - 0.00016 22.0 0.1 0.0012 19.2 0.1 2.2 1 1 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 KDO33525.1 - 0.0078 16.1 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KDO33525.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 KDO33525.1 - 0.015 15.3 0.0 0.093 12.7 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 KDO33525.1 - 0.062 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KDO33525.1 - 0.066 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KDO33525.1 - 0.071 13.5 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KDO33525.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin ArgoMid PF16487.5 KDO33525.1 - 0.093 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute G-alpha PF00503.20 KDO33525.1 - 0.12 11.5 1.4 0.88 8.7 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_25 PF13481.6 KDO33525.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO33525.1 - 0.15 11.8 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO33525.1 - 0.19 11.9 0.2 0.36 11.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KDO33525.1 - 0.2 10.8 0.1 0.27 10.3 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SR-25 PF10500.9 KDO33526.1 - 2.3 7.8 32.9 0.57 9.7 29.9 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HSF_DNA-bind PF00447.17 KDO33528.1 - 8.7e-31 106.4 0.4 8.7e-31 106.4 0.4 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding LPP PF04728.13 KDO33528.1 - 0.011 16.2 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TSC22 PF01166.18 KDO33528.1 - 0.013 15.7 0.1 0.037 14.3 0.1 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4988 PF16378.5 KDO33528.1 - 0.016 14.9 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function SCO1-SenC PF02630.14 KDO33528.1 - 0.018 15.0 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC DUF3294 PF07957.11 KDO33528.1 - 0.026 14.3 0.8 0.039 13.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DivIC PF04977.15 KDO33528.1 - 0.094 12.5 0.0 0.35 10.7 0.1 1.8 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 KDO33528.1 - 0.11 12.9 0.3 0.2 12.2 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HSF_DNA-bind PF00447.17 KDO33529.1 - 2.7e-30 104.9 4.0 2.8e-30 104.8 3.1 1.5 2 0 0 2 2 2 1 HSF-type DNA-binding MscS_porin PF12795.7 KDO33529.1 - 0.0042 16.7 0.3 0.0073 15.9 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain HAUS-augmin3 PF14932.6 KDO33529.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LPP PF04728.13 KDO33529.1 - 0.017 15.5 1.5 0.054 13.9 1.5 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper CAP_N PF01213.19 KDO33529.1 - 0.042 13.3 0.7 0.053 13.0 0.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1664 PF07889.12 KDO33529.1 - 0.078 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 KDO33529.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit TolA_bind_tri PF16331.5 KDO33529.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.6 2 0 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 KDO33529.1 - 0.14 12.8 1.2 0.41 11.3 1.2 1.8 1 1 0 1 1 1 0 SlyX DASH_Hsk3 PF08227.11 KDO33529.1 - 2.1 8.8 8.9 0.26 11.7 3.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like HSF_DNA-bind PF00447.17 KDO33530.1 - 6.6e-23 81.1 2.6 6.6e-23 81.1 2.6 1.8 2 0 0 2 2 1 1 HSF-type DNA-binding TSC22 PF01166.18 KDO33530.1 - 0.00067 19.9 1.3 0.0015 18.8 1.3 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 KDO33530.1 - 0.0017 18.4 0.2 0.0032 17.5 0.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KDO33530.1 - 0.0029 18.0 1.3 0.0064 16.9 1.3 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein COG5 PF10392.9 KDO33530.1 - 0.0062 16.7 0.5 0.011 15.9 0.5 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 KDO33530.1 - 0.0096 16.0 1.4 0.015 15.3 1.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5320 PF17253.2 KDO33530.1 - 0.01 16.9 0.4 0.027 15.5 0.1 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5320) SlyX PF04102.12 KDO33530.1 - 0.015 15.9 0.9 0.034 14.8 0.9 1.6 1 0 0 1 1 1 0 SlyX Dynamitin PF04912.14 KDO33530.1 - 0.016 14.5 0.7 0.022 14.1 0.7 1.1 1 0 0 1 1 1 0 Dynamitin SKA1 PF07160.12 KDO33530.1 - 0.029 14.2 1.2 0.046 13.6 1.2 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Prefoldin PF02996.17 KDO33530.1 - 0.035 14.0 0.2 0.067 13.1 0.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF3543 PF12063.8 KDO33530.1 - 0.051 13.0 0.4 0.089 12.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) DUF2205 PF10224.9 KDO33530.1 - 0.058 13.4 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF812 PF05667.11 KDO33530.1 - 0.061 12.2 0.9 0.076 11.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LPP PF04728.13 KDO33530.1 - 0.079 13.4 1.0 0.21 12.0 1.0 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF4988 PF16378.5 KDO33530.1 - 0.08 12.6 0.4 0.15 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function Seryl_tRNA_N PF02403.22 KDO33530.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Bap31_Bap29_C PF18035.1 KDO33530.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain YlbD_coat PF14071.6 KDO33530.1 - 0.11 12.7 1.7 3.1 8.0 0.9 2.7 2 1 0 3 3 3 0 Putative coat protein DUF5082 PF16888.5 KDO33530.1 - 0.16 12.2 1.2 0.32 11.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Ribosomal_S15 PF00312.22 KDO33530.1 - 0.17 12.1 0.8 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S15 bZIP_1 PF00170.21 KDO33530.1 - 0.23 11.6 0.6 0.44 10.7 0.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor FlaC_arch PF05377.11 KDO33530.1 - 0.71 10.3 3.6 1.4 9.4 3.6 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HSF_DNA-bind PF00447.17 KDO33531.1 - 1.1e-17 64.4 1.9 5e-17 62.3 1.9 2.0 1 1 0 1 1 1 1 HSF-type DNA-binding DUF4988 PF16378.5 KDO33531.1 - 0.00058 19.6 0.4 0.0012 18.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function TSC22 PF01166.18 KDO33531.1 - 0.0036 17.6 0.6 0.0036 17.6 0.6 1.8 2 0 0 2 2 1 1 TSC-22/dip/bun family PPPI_inhib PF14895.6 KDO33531.1 - 0.0067 15.6 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor LPP PF04728.13 KDO33531.1 - 0.0073 16.7 0.7 0.018 15.4 0.7 1.7 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Bap31_Bap29_C PF18035.1 KDO33531.1 - 0.0082 16.1 0.4 0.013 15.5 0.4 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF812 PF05667.11 KDO33531.1 - 0.012 14.6 1.0 0.014 14.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.21 KDO33531.1 - 0.043 13.9 1.0 0.085 13.0 1.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor Prefoldin PF02996.17 KDO33531.1 - 0.052 13.5 0.8 1.3 9.0 0.3 2.1 1 1 0 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 KDO33531.1 - 0.073 13.3 0.5 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 KDO33531.1 - 0.082 13.0 1.9 0.13 12.4 1.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3573 PF12097.8 KDO33531.1 - 0.082 11.7 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Phage_GP20 PF06810.11 KDO33531.1 - 0.098 12.5 1.9 0.17 11.7 1.9 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 TMPIT PF07851.13 KDO33531.1 - 0.1 11.9 0.2 0.1 11.9 0.2 1.5 2 0 0 2 2 2 0 TMPIT-like protein GAT PF03127.14 KDO33531.1 - 0.1 12.9 0.8 0.22 11.9 0.8 1.5 1 0 0 1 1 1 0 GAT domain DUF2205 PF10224.9 KDO33531.1 - 0.16 11.9 0.4 0.16 11.9 0.4 1.7 2 0 0 2 2 1 0 Short coiled-coil protein DivIC PF04977.15 KDO33531.1 - 0.17 11.7 0.8 0.33 10.7 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator EDR1 PF14381.6 KDO33531.1 - 0.3 10.8 2.5 1.9 8.2 1.0 2.1 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF16 PF01519.16 KDO33531.1 - 0.5 10.9 4.8 0.98 9.9 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 HSF_DNA-bind PF00447.17 KDO33532.1 - 2.9e-24 85.5 0.2 5e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Bacillus_HBL PF05791.11 KDO33532.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) HSF_DNA-bind PF00447.17 KDO33533.1 - 1.8e-27 95.8 2.2 3e-27 95.1 2.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HAUS-augmin3 PF14932.6 KDO33533.1 - 0.0065 16.1 0.4 0.01 15.5 0.4 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 SlyX PF04102.12 KDO33533.1 - 0.0099 16.5 0.4 0.02 15.5 0.4 1.5 1 0 0 1 1 1 1 SlyX Tropomyosin_1 PF12718.7 KDO33533.1 - 0.029 14.5 0.7 0.04 14.1 0.7 1.2 1 0 0 1 1 1 0 Tropomyosin like DivIC PF04977.15 KDO33533.1 - 0.11 12.3 1.0 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 Septum formation initiator HSF_DNA-bind PF00447.17 KDO33534.1 - 2.7e-26 92.0 1.8 4.1e-26 91.4 1.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 KDO33535.1 - 6.6e-27 94.0 0.3 9.6e-27 93.5 0.3 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding SPESP1 PF15754.5 KDO33535.1 - 0.0078 15.4 0.3 0.011 15.0 0.3 1.1 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 MscS_porin PF12795.7 KDO33535.1 - 0.056 13.0 1.0 0.084 12.4 1.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF5450 PF17529.2 KDO33535.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5450) HSF_DNA-bind PF00447.17 KDO33536.1 - 4.4e-25 88.1 2.0 5.6e-25 87.8 2.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 KDO33537.1 - 3.5e-18 66.0 0.1 4.8e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 KDO33538.1 - 6.2e-29 100.5 0.3 9.6e-29 99.9 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Bap31_Bap29_C PF18035.1 KDO33538.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4988 PF16378.5 KDO33538.1 - 0.064 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function NPV_P10 PF05531.12 KDO33538.1 - 0.25 11.9 0.7 0.49 10.9 0.1 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Swi3 PF07962.12 KDO33539.1 - 3e-16 59.2 0.0 4.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SEEK1 PF15357.6 KDO33539.1 - 0.034 14.3 0.2 0.075 13.2 0.2 1.6 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 TPR_14 PF13428.6 KDO33541.1 - 8.6e-12 44.8 42.5 0.12 13.2 0.3 13.2 9 4 6 15 15 15 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33541.1 - 1e-07 31.5 17.1 0.0035 17.3 0.5 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33541.1 - 4e-06 27.0 17.3 0.4 11.0 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33541.1 - 6.6e-06 25.9 5.0 0.01 16.0 0.2 6.5 9 0 0 9 9 8 1 Tetratricopeptide repeat Suf PF05843.14 KDO33541.1 - 6.9e-06 26.3 3.6 2.3 8.2 0.0 5.3 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KDO33541.1 - 7e-05 22.8 12.0 0.092 12.7 0.0 6.0 8 2 0 8 8 8 2 Mad3/BUB1 homology region 1 TPR_11 PF13414.6 KDO33541.1 - 0.00082 19.0 0.7 22 4.8 0.0 5.7 5 0 0 5 5 5 0 TPR repeat TPR_15 PF13429.6 KDO33541.1 - 0.0011 18.2 13.4 0.02 14.1 1.0 4.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33541.1 - 0.0014 18.3 4.3 0.1 12.4 0.1 5.6 8 0 0 8 8 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KDO33541.1 - 0.0018 18.0 1.3 0.24 11.1 0.0 3.5 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KDO33541.1 - 0.0027 18.2 10.6 15 6.2 0.1 5.9 4 1 2 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KDO33541.1 - 0.0037 16.5 4.4 0.33 10.0 0.1 4.6 2 2 3 5 5 5 1 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 KDO33541.1 - 0.045 13.8 12.8 0.078 13.0 0.1 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO33541.1 - 1.7 9.5 5.6 8.1 7.4 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33541.1 - 6.9 7.5 14.1 23 5.9 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat AMP-binding PF00501.28 KDO33542.1 - 2.8e-91 306.2 0.1 3.4e-91 306.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO33542.1 - 1.5e-05 25.8 0.0 4.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KDO33542.1 - 0.025 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter HSF_DNA-bind PF00447.17 KDO33543.1 - 7.6e-28 97.0 2.4 7.6e-28 97.0 2.4 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Bap31_Bap29_C PF18035.1 KDO33543.1 - 5.4e-05 23.1 0.0 7.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HCMV_UL139 PF12507.8 KDO33543.1 - 0.022 15.2 0.1 0.053 13.9 0.1 1.6 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein UBA2_C PF16195.5 KDO33543.1 - 0.031 15.0 2.2 0.065 13.9 2.2 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DivIC PF04977.15 KDO33543.1 - 0.062 13.1 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.12 KDO33543.1 - 0.073 13.1 0.6 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 KDO33543.1 - 0.1 12.4 0.3 0.24 11.2 0.1 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Filament PF00038.21 KDO33543.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein Cast PF10174.9 KDO33543.1 - 0.15 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone TMF_DNA_bd PF12329.8 KDO33543.1 - 0.21 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YqjK PF13997.6 KDO33544.1 - 6.7 7.0 6.8 0.76 10.1 0.3 2.7 3 0 0 3 3 3 0 YqjK-like protein cNMP_binding PF00027.29 KDO33545.1 - 1.8e-15 56.8 0.3 1.9e-07 31.0 0.1 3.5 2 2 0 2 2 2 2 Cyclic nucleotide-binding domain DUF2939 PF11159.8 KDO33545.1 - 0.083 13.3 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Aldo_ket_red PF00248.21 KDO33546.1 - 2e-22 79.8 0.0 4.9e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 KDO33547.1 - 7.1e-62 208.8 2.5 1.3e-60 204.7 2.5 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO33547.1 - 1.3e-08 35.7 2.4 1.3e-08 35.7 2.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO33547.1 - 2.9e-05 23.8 3.1 0.001 18.8 1.6 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KDO33547.1 - 0.0011 17.8 0.0 0.89 8.2 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KDO33547.1 - 0.0023 17.4 0.6 0.012 15.1 0.1 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KDO33547.1 - 0.0095 14.9 0.1 0.019 13.9 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme F5_F8_type_C PF00754.25 KDO33548.1 - 0.00014 22.0 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 KDO33548.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 XRCC1 N terminal domain Sugar_tr PF00083.24 KDO33549.1 - 2.9e-38 131.9 21.0 3.8e-38 131.5 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO33549.1 - 1.4e-31 109.7 33.8 1.4e-31 109.7 33.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KDO33549.1 - 7.5e-06 25.5 19.7 0.00019 20.8 3.7 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB EF-hand_7 PF13499.6 KDO33554.1 - 1.2e-16 60.9 2.2 5.3e-05 23.6 0.1 5.2 4 1 2 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.6 KDO33554.1 - 1.2e-15 56.1 0.1 1.9e-05 24.2 0.1 6.5 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 KDO33554.1 - 1.7e-14 53.4 5.5 7.8e-07 28.8 0.2 6.0 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_1 PF00036.32 KDO33554.1 - 2.2e-13 48.7 1.5 2.6e-05 23.4 0.1 5.8 7 0 0 7 7 7 2 EF hand EF-hand_5 PF13202.6 KDO33554.1 - 5.8e-07 28.7 0.7 0.0056 16.1 0.1 2.7 2 0 0 2 2 2 2 EF hand DUF4483 PF14825.6 KDO33554.1 - 9e-06 25.5 1.1 3.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4483) FAT PF02259.23 KDO33554.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 FAT domain K_oxygenase PF13434.6 KDO33554.1 - 0.056 12.6 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) CHAT PF12770.7 KDO33555.1 - 9.3e-15 54.8 1.7 1.8e-14 53.9 1.7 1.4 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 KDO33555.1 - 3.3e-11 43.4 0.2 1.6e-10 41.1 0.0 2.3 3 0 0 3 3 3 1 NACHT domain TPR_12 PF13424.6 KDO33555.1 - 2.3e-05 24.6 0.9 0.00014 22.1 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 KDO33555.1 - 5.1e-05 23.7 4.0 0.00015 22.2 1.2 3.2 2 1 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 KDO33555.1 - 0.0014 18.6 0.3 0.49 10.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KDO33555.1 - 0.0042 17.4 0.1 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Peptidase_C14 PF00656.22 KDO33555.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Caspase domain TPR_10 PF13374.6 KDO33555.1 - 0.0073 16.1 0.3 0.071 13.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33555.1 - 0.012 16.2 0.0 0.12 13.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 KDO33555.1 - 0.022 15.2 0.0 0.066 13.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KDO33555.1 - 0.024 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KDO33555.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NTPase TPR_1 PF00515.28 KDO33555.1 - 0.11 12.4 0.0 3.8 7.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 KDO33556.1 - 1.6e-37 129.1 0.1 1.3e-35 122.8 0.1 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO33556.1 - 4.2e-19 68.9 0.0 1.4e-17 64.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KDO33556.1 - 0.00022 20.5 0.2 0.0013 17.9 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KDO33556.1 - 0.00038 19.8 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Pox_Ag35 PF03286.14 KDO33556.1 - 0.28 11.0 3.8 0.56 10.0 3.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 KDO33556.1 - 4.1 7.8 7.4 1.5 9.3 2.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSF_DNA-bind PF00447.17 KDO33557.1 - 5.5e-28 97.4 0.3 9.4e-28 96.7 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding MAD PF05557.13 KDO33557.1 - 0.015 13.7 0.1 0.018 13.5 0.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Erythro_esteras PF05139.14 KDO33557.1 - 0.017 14.9 0.2 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 Erythromycin esterase LPP PF04728.13 KDO33557.1 - 0.04 14.3 0.3 0.08 13.3 0.3 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper FadR_C PF07840.12 KDO33557.1 - 0.12 12.3 0.6 0.2 11.5 0.6 1.3 1 0 0 1 1 1 0 FadR C-terminal domain DUF4988 PF16378.5 KDO33557.1 - 0.17 11.5 0.2 0.28 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function FlaC_arch PF05377.11 KDO33557.1 - 0.34 11.3 1.1 0.6 10.5 1.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HSF_DNA-bind PF00447.17 KDO33558.1 - 1.6e-30 105.5 2.2 1.6e-30 105.5 2.2 1.5 2 0 0 2 2 2 1 HSF-type DNA-binding Seryl_tRNA_N PF02403.22 KDO33558.1 - 0.054 13.7 0.2 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IZUMO PF15005.6 KDO33558.1 - 0.23 12.0 0.8 0.9 10.0 0.5 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated HSF_DNA-bind PF00447.17 KDO33559.1 - 2.8e-26 91.9 0.6 4.7e-26 91.2 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Pox_A_type_inc PF04508.12 KDO33559.1 - 0.00079 19.2 0.2 0.0042 16.9 0.1 2.1 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat V_ATPase_I PF01496.19 KDO33559.1 - 0.0073 14.3 0.8 0.5 8.2 0.0 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family DUF4363 PF14276.6 KDO33559.1 - 0.13 12.4 1.1 0.26 11.4 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Peptidase_C48 PF02902.19 KDO33560.1 - 4.6e-18 65.9 0.1 2.5e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain EF-hand_1 PF00036.32 KDO33561.1 - 1.2e-28 96.5 4.2 1.5e-06 27.3 0.0 7.4 7 0 0 7 7 7 5 EF hand EF-hand_6 PF13405.6 KDO33561.1 - 2.2e-28 95.7 7.7 3.7e-06 26.4 0.1 7.7 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 KDO33561.1 - 5e-25 87.8 1.3 1.1e-07 32.2 0.2 5.9 4 2 1 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 KDO33561.1 - 5.4e-22 77.4 1.8 2.8e-06 27.1 0.0 9.1 7 3 3 10 10 10 5 EF-hand domain pair EF-hand_5 PF13202.6 KDO33561.1 - 3.1e-17 61.2 3.3 9.5e-06 24.9 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 KDO33561.1 - 2.9e-06 27.5 0.2 8.4 6.8 0.0 6.0 5 2 1 6 6 6 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KDO33561.1 - 0.00013 22.3 0.0 6.6 7.1 0.0 4.3 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KDO33561.1 - 0.025 14.6 0.0 2.7 8.0 0.0 3.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KDO33561.1 - 0.1 12.8 1.2 26 5.1 0.0 3.2 4 1 0 4 4 4 0 Dockerin type I domain EF-hand_10 PF14788.6 KDO33561.1 - 3.4 7.6 4.7 26 4.8 0.0 4.3 6 0 0 6 6 6 0 EF hand REC114-like PF15165.6 KDO33562.1 - 0.015 15.1 0.1 0.043 13.6 0.1 1.7 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like Elicitin PF00964.17 KDO33562.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Elicitin Ofd1_CTDD PF10637.9 KDO33562.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Pex24p PF06398.11 KDO33562.1 - 0.22 10.5 1.1 0.45 9.4 1.1 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Strumpellin PF10266.9 KDO33563.1 - 0 1349.7 0.8 0 1348.6 0.8 1.5 1 1 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin TetR_C_11 PF16859.5 KDO33563.1 - 0.064 13.6 0.2 2.5 8.4 0.0 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF4375 PF14300.6 KDO33563.1 - 4.7 7.5 5.6 21 5.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Aa_trans PF01490.18 KDO33564.1 - 6.9e-38 130.4 22.9 8e-38 130.2 22.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_72 PF03198.14 KDO33565.1 - 2.9e-38 131.9 0.0 1.7e-36 126.0 0.0 2.1 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KDO33565.1 - 0.088 12.2 0.0 0.85 9.0 0.0 2.2 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Cdh1_DBD_1 PF18196.1 KDO33566.1 - 0.85 9.9 4.2 0.85 9.9 0.3 2.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DAO PF01266.24 KDO33569.1 - 5.8e-60 203.7 0.2 6.5e-60 203.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KDO33569.1 - 0.00033 20.0 0.1 0.00051 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KDO33569.1 - 0.00059 19.0 0.2 0.0012 18.1 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KDO33569.1 - 0.00064 18.7 0.1 0.065 12.1 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KDO33569.1 - 0.00071 19.8 0.5 0.0014 18.8 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO33569.1 - 0.0014 18.0 0.3 0.015 14.5 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KDO33569.1 - 0.0023 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KDO33569.1 - 0.015 15.4 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KDO33569.1 - 0.016 15.7 0.2 0.069 13.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO33569.1 - 0.043 12.9 0.2 0.11 11.5 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein LRR_6 PF13516.6 KDO33571.1 - 3.2e-34 114.1 72.4 0.00024 20.9 0.4 18.1 19 0 0 19 19 19 14 Leucine Rich repeat LRR_4 PF12799.7 KDO33571.1 - 2.4e-21 75.4 38.0 0.0032 17.8 0.1 10.7 4 2 9 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO33571.1 - 2e-12 46.7 36.5 0.0016 18.2 0.3 8.5 5 2 3 9 9 9 7 Leucine rich repeat LRR_1 PF00560.33 KDO33571.1 - 6.5e-08 32.1 41.8 6.8 7.7 0.3 14.5 15 3 0 15 15 15 5 Leucine Rich Repeat RNA_pol_A_CTD PF03118.15 KDO33571.1 - 0.0088 15.8 0.2 2 8.2 0.0 3.5 3 0 0 3 3 3 1 Bacterial RNA polymerase, alpha chain C terminal domain LRR_9 PF14580.6 KDO33571.1 - 0.35 10.4 3.4 7.5 6.0 0.1 3.2 1 1 2 3 3 3 0 Leucine-rich repeat DHFR_2 PF06442.11 KDO33571.1 - 0.5 10.2 1.6 12 5.8 0.0 3.3 4 0 0 4 4 4 0 R67 dihydrofolate reductase Acyl_transf_3 PF01757.22 KDO33572.1 - 6e-22 78.2 29.6 8.6e-22 77.6 28.6 1.7 1 1 1 2 2 2 1 Acyltransferase family TPPK_C PF12555.8 KDO33572.1 - 0.031 14.3 0.9 0.23 11.5 0.9 2.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF4405 PF14358.6 KDO33572.1 - 3.3 8.3 12.1 6.5 7.4 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Peptidase_S9 PF00326.21 KDO33574.1 - 1.1e-35 123.1 0.0 2e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KDO33574.1 - 3.8e-26 91.7 0.0 1.8e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VHL PF01847.16 KDO33574.1 - 9.6e-08 31.8 0.0 2.7e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 VHL beta domain Esterase PF00756.20 KDO33574.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Kinesin PF00225.23 KDO33575.1 - 2.7e-61 207.3 0.0 9.9e-36 123.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KDO33575.1 - 6.8e-17 61.8 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 KDO33576.1 - 4.4e-64 216.5 0.4 2.3e-37 128.7 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KDO33576.1 - 6.3e-14 52.1 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF4156 PF13698.6 KDO33576.1 - 0.043 14.1 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) Kinesin PF00225.23 KDO33577.1 - 2.8e-62 210.6 0.3 1.4e-36 126.1 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KDO33577.1 - 6.3e-14 52.1 0.0 1.5e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF4260 PF14079.6 KDO33578.1 - 2e-27 95.4 1.9 2.4e-27 95.1 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Methyltransf_16 PF10294.9 KDO33579.1 - 8.5e-29 100.5 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF2530 PF10745.9 KDO33579.1 - 0.0011 19.2 0.5 0.0025 18.0 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) MTS PF05175.14 KDO33579.1 - 0.024 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KDO33579.1 - 0.024 14.0 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KDO33579.1 - 0.045 13.6 0.0 0.091 12.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Pkinase_Tyr PF07714.17 KDO33580.1 - 9.5e-16 57.8 0.0 3.2e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO33580.1 - 6.1e-12 45.5 0.0 1.6e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO33580.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PspB PF06667.12 KDO33580.1 - 0.17 11.9 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Phage shock protein B MFS_1 PF07690.16 KDO33582.1 - 3.7e-50 170.8 37.4 5.5e-50 170.3 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KDO33582.1 - 3.5e-07 29.8 4.3 3.5e-07 29.8 4.3 2.9 2 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KDO33582.1 - 7.5e-05 21.8 9.0 7.5e-05 21.8 9.0 2.9 1 1 1 3 3 3 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 KDO33582.1 - 0.0088 15.1 0.3 0.0088 15.1 0.3 3.3 2 2 0 3 3 3 1 Nucleoside H+ symporter F-box-like PF12937.7 KDO33583.1 - 3.4e-07 30.0 3.0 6.2e-07 29.2 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KDO33583.1 - 1.8e-06 27.6 0.2 4.1e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KDO33583.1 - 0.071 12.7 0.3 0.19 11.3 0.3 1.7 1 1 0 1 1 1 0 F-box FH2 PF02181.23 KDO33584.1 - 1.5e-66 225.1 6.0 1.9e-66 224.7 6.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 KDO33584.1 - 3.2e-33 115.3 7.8 1.1e-12 48.7 0.1 3.8 4 0 0 4 4 4 3 Subunit CCDC53 of WASH complex VATC PF18716.1 KDO33586.1 - 3.7e-19 68.3 1.6 6.4e-19 67.5 1.6 1.4 1 0 0 1 1 1 1 Vms1-associating treble clef domain PTE PF02126.18 KDO33586.1 - 1.7e-12 47.4 0.0 2.2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotriesterase family LPD22 PF18834.1 KDO33586.1 - 0.068 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 zf-MYND PF01753.18 KDO33586.1 - 0.17 12.0 1.0 0.45 10.7 1.0 1.7 1 1 0 1 1 1 0 MYND finger Tyr-DNA_phospho PF06087.12 KDO33589.1 - 6e-89 298.9 0.0 6.8e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Orn_Arg_deC_N PF02784.16 KDO33591.1 - 2.5e-60 203.9 0.0 3e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KDO33591.1 - 7e-08 32.6 0.0 7.5e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HAT_KAT11 PF08214.11 KDO33592.1 - 4.5e-30 105.1 0.6 4.9e-28 98.4 0.4 2.7 1 1 0 1 1 1 1 Histone acetylation protein zf-TAZ PF02135.16 KDO33592.1 - 1.4e-25 89.5 69.6 3.8e-10 40.1 20.0 5.3 4 2 1 5 5 5 4 TAZ zinc finger Bromodomain PF00439.25 KDO33592.1 - 4.8e-12 45.8 0.1 2.1e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Bromodomain ZZ PF00569.17 KDO33592.1 - 2.9e-07 30.2 4.3 2.9e-07 30.2 4.3 5.0 6 0 0 6 6 6 1 Zinc finger, ZZ type PHD PF00628.29 KDO33592.1 - 6.6e-06 25.9 3.8 6.6e-06 25.9 3.8 5.1 6 1 1 7 7 7 1 PHD-finger KIX_2 PF16987.5 KDO33592.1 - 0.0021 18.0 1.4 0.01 15.8 1.4 2.3 1 0 0 1 1 1 1 KIX domain DUF902 PF06001.13 KDO33592.1 - 0.0039 17.6 3.6 0.012 16.1 3.6 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) Ribophorin_II PF05817.14 KDO33593.1 - 8.4e-62 209.6 4.3 1.2e-61 209.1 4.3 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Bax1-I PF01027.20 KDO33593.1 - 0.022 14.6 8.3 0.037 13.8 8.3 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 ChuX_HutX PF06228.13 KDO33594.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX FF PF01846.19 KDO33595.1 - 5.3e-27 93.7 16.4 9.2e-11 41.8 0.0 5.9 7 1 0 7 7 7 4 FF domain WW PF00397.26 KDO33595.1 - 0.00031 20.8 0.6 0.001 19.1 0.1 2.2 2 0 0 2 2 2 1 WW domain SR-25 PF10500.9 KDO33595.1 - 0.08 12.5 38.3 0.16 11.5 38.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KDO33595.1 - 0.8 8.5 13.8 1.5 7.6 13.8 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF_4G1 PF12152.8 KDO33596.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 MAGI_u5 PF16666.5 KDO33596.1 - 7.1 6.8 15.6 0.11 12.7 3.5 2.8 3 0 0 3 3 3 0 Unstructured region on MAGI MFS_MOT1 PF16983.5 KDO33597.1 - 4.1e-51 172.0 24.6 1.8e-27 95.9 8.9 3.1 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily DUF3953 PF13129.6 KDO33597.1 - 0.049 13.4 0.4 0.049 13.4 0.4 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3953) CHD5 PF04420.14 KDO33597.1 - 0.31 10.9 0.9 1 9.2 0.1 2.2 2 0 0 2 2 2 0 CHD5-like protein AAA_assoc_2 PF16193.5 KDO33599.1 - 0.00093 19.5 0.1 0.0026 18.1 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DUF2968 PF11180.8 KDO33599.1 - 0.32 10.6 4.0 0.79 9.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Rad17 PF03215.15 KDO33600.1 - 1.4e-23 83.7 0.0 1.2e-22 80.8 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KDO33600.1 - 4.1e-08 33.8 0.1 6e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KDO33600.1 - 7.6e-06 26.4 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KDO33600.1 - 0.00011 22.5 0.0 0.00023 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KDO33600.1 - 0.00026 20.7 0.0 0.00083 19.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KDO33600.1 - 0.00039 20.2 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO33600.1 - 0.0015 19.1 0.0 0.0025 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO33600.1 - 0.0017 18.5 0.2 0.0041 17.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 KDO33600.1 - 0.0053 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 KDO33600.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KDO33600.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-RanBP PF00641.18 KDO33600.1 - 0.022 14.0 0.3 0.036 13.4 0.3 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others AAA_5 PF07728.14 KDO33600.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KDO33600.1 - 0.031 14.6 0.0 0.089 13.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 KDO33600.1 - 0.038 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KDO33600.1 - 0.045 14.3 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 KDO33600.1 - 0.051 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_PrkA PF08298.11 KDO33600.1 - 0.064 12.1 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_25 PF13481.6 KDO33600.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KDO33600.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 KDO33600.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 KDO33600.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KDO33600.1 - 0.12 12.9 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KDO33600.1 - 0.13 12.2 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KDO33600.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 KDO33600.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KDO33600.1 - 0.21 11.8 0.4 18 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain E2F_TDP PF02319.20 KDO33601.1 - 5e-37 125.8 0.2 3.1e-19 68.8 0.3 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KDO33601.1 - 0.0076 16.1 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB CRT-like PF08627.10 KDO33602.1 - 4.8e-117 390.6 18.9 5.4e-117 390.5 18.9 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KDO33602.1 - 9.9e-07 28.2 13.4 0.00017 20.9 14.4 2.6 1 1 1 2 2 2 2 UAA transporter family SLC35F PF06027.12 KDO33602.1 - 0.00014 21.5 5.9 0.00014 21.5 5.9 2.1 2 0 0 2 2 2 2 Solute carrier family 35 EamA PF00892.20 KDO33602.1 - 0.003 17.7 28.0 0.0077 16.4 10.5 3.2 3 0 0 3 3 3 2 EamA-like transporter family Acyltransferase PF01553.21 KDO33603.1 - 2.6e-19 69.2 0.0 5.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KDO33603.1 - 8e-14 51.5 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Pkinase PF00069.25 KDO33604.1 - 5.1e-60 203.1 0.0 6.7e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33604.1 - 2e-30 105.9 0.0 2.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO33604.1 - 0.00056 19.0 0.1 0.00098 18.2 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO33604.1 - 0.0061 16.5 0.5 0.021 14.7 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO33604.1 - 0.0085 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KDO33604.1 - 0.054 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KDO33604.1 - 0.19 11.0 1.0 0.23 10.8 0.4 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_transf_1 PF00534.20 KDO33605.1 - 0.00021 20.9 0.1 0.00047 19.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SUV3_C PF12513.8 KDO33606.1 - 2.5e-13 49.7 0.6 5.5e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KDO33606.1 - 7.6e-12 44.9 0.3 2e-11 43.6 0.3 1.8 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KDO33606.1 - 2e-10 41.0 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 KDO33606.1 - 0.0029 17.7 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Suv3 helical N-terminal domain RepA_C PF04796.12 KDO33606.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Plasmid encoded RepA protein NPCBM PF08305.11 KDO33608.1 - 2.4e-19 69.9 0.0 4.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 NPCBM/NEW2 domain SPRY PF00622.28 KDO33608.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain F5_F8_type_C PF00754.25 KDO33608.1 - 0.0019 18.3 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain zf-RanBP PF00641.18 KDO33608.1 - 0.062 12.6 4.6 0.024 14.0 1.3 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HECT PF00632.25 KDO33609.1 - 2.7e-60 204.5 0.0 4.5e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.6 KDO33609.1 - 4.4e-12 46.4 0.0 1.4e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 KDO33609.1 - 3.3e-05 23.7 1.5 8.6e-05 22.3 0.4 2.4 2 0 0 2 2 2 1 UBA/TS-N domain SPRY PF00622.28 KDO33609.1 - 0.0014 18.8 0.0 0.0081 16.3 0.0 2.1 2 0 0 2 2 2 1 SPRY domain MT-A70 PF05063.14 KDO33611.1 - 1.4e-26 93.4 0.0 1.9e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 DEAD PF00270.29 KDO33612.1 - 6.1e-48 162.9 0.0 9.8e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO33612.1 - 5.9e-29 100.7 0.1 7.3e-27 93.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO33612.1 - 1.4e-07 31.7 0.0 3.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATP-synt_DE_N PF02823.16 KDO33613.1 - 1.8e-13 50.2 0.4 3.7e-13 49.2 0.1 1.7 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ank_2 PF12796.7 KDO33614.1 - 1.8e-15 57.3 2.1 9.8e-11 42.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO33614.1 - 2.9e-15 54.8 1.2 0.00089 19.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KDO33614.1 - 3.3e-13 49.9 0.2 0.00011 22.7 0.0 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO33614.1 - 9.8e-13 47.9 7.7 0.0001 22.6 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KDO33614.1 - 1.4e-11 44.4 2.7 6.5e-06 26.3 0.1 4.3 3 2 2 5 5 5 2 Ankyrin repeats (many copies) FYVE PF01363.21 KDO33614.1 - 4.3e-07 30.0 7.9 7.6e-07 29.2 7.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger PDZ PF00595.24 KDO33614.1 - 0.00071 19.9 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain TPR_16 PF13432.6 KDO33615.1 - 1.1e-23 83.6 32.5 3.1e-06 27.7 0.1 5.6 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33615.1 - 1.1e-18 65.7 11.5 0.00022 21.1 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33615.1 - 1.2e-18 67.4 15.3 3.1e-05 24.4 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33615.1 - 2e-16 59.1 2.1 1.8e-05 24.3 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33615.1 - 6.3e-15 54.6 27.9 0.0021 18.7 0.0 8.7 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33615.1 - 2.6e-13 49.0 0.3 0.00017 21.5 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33615.1 - 3.6e-11 43.2 25.3 7.6e-05 22.9 0.8 5.7 4 1 4 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33615.1 - 1.8e-10 40.4 4.6 0.037 14.4 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33615.1 - 5.2e-09 36.2 7.0 0.36 11.6 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33615.1 - 2.9e-08 33.2 16.8 0.0037 17.2 0.1 6.8 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO33615.1 - 4.2e-08 32.8 17.5 5.6e-05 22.9 0.3 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33615.1 - 5.1e-08 32.5 2.8 0.073 12.8 0.0 5.6 3 1 3 6 6 6 2 TPR repeat ANAPC3 PF12895.7 KDO33615.1 - 2.8e-06 27.4 0.5 0.02 15.1 0.0 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KDO33615.1 - 0.00037 20.6 19.7 0.045 13.9 1.6 5.3 3 1 3 6 6 6 3 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 KDO33615.1 - 0.0035 15.8 0.0 0.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_15 PF13429.6 KDO33615.1 - 0.011 14.9 8.5 0.3 10.2 0.0 3.7 3 1 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KDO33615.1 - 0.029 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit BTAD PF03704.17 KDO33615.1 - 0.065 13.7 0.4 0.065 13.7 0.4 4.5 5 1 1 6 6 5 0 Bacterial transcriptional activator domain BT1 PF03092.16 KDO33616.1 - 2.8e-11 42.4 0.4 2.8e-11 42.4 0.4 2.7 3 0 0 3 3 3 2 BT1 family Stealth_CR2 PF11380.8 KDO33617.1 - 2.6e-25 88.7 0.1 6.6e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KDO33617.1 - 3.2e-07 30.0 0.2 7.4e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 EABR PF12180.8 KDO33618.1 - 0.015 14.9 1.7 1.1 8.9 0.1 3.2 3 0 0 3 3 3 0 TSG101 and ALIX binding domain of CEP55 DUF572 PF04502.13 KDO33618.1 - 0.02 14.6 6.1 0.031 13.9 6.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) UBX PF00789.20 KDO33619.1 - 1.5e-17 63.5 0.0 2.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain MCD PF05292.11 KDO33619.1 - 0.026 14.1 2.4 0.049 13.2 2.4 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain ARGLU PF15346.6 KDO33619.1 - 0.77 9.6 24.8 1.1 9.2 24.8 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Sin_N PF04801.13 KDO33619.1 - 0.8 8.8 7.9 1.1 8.4 7.9 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region SLC12 PF03522.15 KDO33619.1 - 1.4 7.9 3.7 1.8 7.5 3.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sua5_yciO_yrdC PF01300.18 KDO33620.1 - 8.5e-47 159.0 0.0 1.2e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KDO33620.1 - 4.4e-12 46.7 0.0 7.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ribosomal_S6 PF01250.17 KDO33621.1 - 9.6e-14 51.4 0.0 2.2e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6 DUF2344 PF10105.9 KDO33621.1 - 0.14 12.0 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) CutA1 PF03091.15 KDO33621.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein DUF1433 PF07252.11 KDO33621.1 - 0.33 11.2 2.7 0.8 10.0 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1433) La PF05383.17 KDO33622.1 - 4.2e-16 58.7 0.1 9.2e-16 57.6 0.1 1.6 1 0 0 1 1 1 1 La domain PBP_N PF17093.5 KDO33623.1 - 1 9.6 7.0 3 8.1 6.9 2.0 1 1 0 1 1 1 0 Penicillin-binding protein N-terminus SYF2 PF08231.12 KDO33625.1 - 2.5e-33 115.7 7.5 2.5e-33 115.7 7.5 1.6 1 1 1 2 2 2 1 SYF2 splicing factor SNARE_assoc PF09335.11 KDO33626.1 - 1.1e-14 54.9 3.0 1.1e-14 54.9 3.0 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein TetR_C_20 PF17925.1 KDO33626.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Med10 PF09748.9 KDO33627.1 - 7e-10 38.9 0.0 9.4e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex IL11 PF07400.11 KDO33627.1 - 0.075 12.7 0.3 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Interleukin 11 WD40 PF00400.32 KDO33628.1 - 5.9e-20 71.2 2.9 0.0021 18.8 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO33628.1 - 6.3e-12 45.6 0.2 4.3e-05 23.7 0.4 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO33628.1 - 2.8e-07 29.6 3.0 2.5e-05 23.2 1.5 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KDO33628.1 - 0.041 12.8 0.1 0.15 11.0 0.2 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SDA1 PF05285.12 KDO33628.1 - 0.056 12.9 12.8 0.086 12.2 12.8 1.4 1 0 0 1 1 1 0 SDA1 Ge1_WD40 PF16529.5 KDO33628.1 - 0.13 11.2 1.6 4.7 6.1 0.1 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Exo_endo_phos PF03372.23 KDO33629.1 - 1.9e-11 43.9 0.3 4.1e-11 42.8 0.3 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_31 PF13847.6 KDO33630.1 - 1e-15 57.8 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33630.1 - 3.5e-14 53.3 0.1 1.3e-13 51.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO33630.1 - 3.7e-13 49.9 0.0 6.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33630.1 - 1.6e-07 32.0 0.0 2.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO33630.1 - 3.8e-07 29.7 0.0 6.3e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KDO33630.1 - 0.00075 19.1 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KDO33630.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 KDO33630.1 - 0.0016 17.7 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MetW PF07021.12 KDO33630.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 KDO33630.1 - 0.017 16.2 0.0 0.025 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KDO33630.1 - 0.041 14.0 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_17 PF12692.7 KDO33630.1 - 0.044 13.8 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_32 PF13679.6 KDO33630.1 - 0.05 13.6 0.0 0.05 13.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Sec1 PF00995.23 KDO33631.1 - 2.5e-90 304.4 0.0 2.9e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CLASP_N PF12348.8 KDO33632.1 - 1e-09 38.3 0.4 0.015 14.9 0.0 4.9 5 0 0 5 5 5 3 CLASP N terminal HEAT PF02985.22 KDO33632.1 - 0.00035 20.6 11.1 71 4.1 0.0 9.9 11 0 0 11 11 11 0 HEAT repeat Ribosomal_S5_C PF03719.15 KDO33632.1 - 0.076 12.5 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain IMS_C PF11799.8 KDO33632.1 - 0.078 13.7 0.9 3.2 8.5 0.0 3.4 3 1 0 3 3 3 0 impB/mucB/samB family C-terminal domain HEAT_EZ PF13513.6 KDO33632.1 - 3.2 8.4 6.7 73 4.0 0.0 6.4 7 0 0 7 7 7 0 HEAT-like repeat Transglut_core PF01841.19 KDO33634.1 - 2.8e-15 56.7 0.2 7.7e-15 55.3 0.2 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KDO33634.1 - 4e-09 36.3 0.1 8.5e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PUB PF09409.10 KDO33634.1 - 3.5e-08 33.3 0.0 1.3e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 PUB domain AZUL PF16558.5 KDO33634.1 - 0.00018 21.6 3.4 0.00022 21.4 0.2 2.8 3 0 0 3 3 3 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Laminin_G_3 PF13385.6 KDO33634.1 - 0.00099 19.3 0.1 0.0044 17.2 0.1 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Thyroglob_assoc PF16597.5 KDO33634.1 - 0.087 13.2 1.8 0.23 11.8 1.8 1.7 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain PAW PF04721.17 KDO33634.1 - 0.19 11.5 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW YfmQ PF10787.9 KDO33634.1 - 0.19 11.5 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group LRR_4 PF12799.7 KDO33635.1 - 3.3e-13 49.6 1.9 0.0036 17.7 0.0 7.1 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO33635.1 - 2.3e-10 39.7 16.1 0.11 12.7 0.1 9.3 11 0 0 11 11 11 4 Leucine Rich repeat LRR_8 PF13855.6 KDO33635.1 - 0.0035 17.1 6.9 0.18 11.6 0.0 4.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 KDO33635.1 - 0.15 12.7 14.8 19 6.3 0.0 7.5 9 0 0 9 9 9 0 Leucine Rich Repeat Kinesin PF00225.23 KDO33636.1 - 2.1e-87 293.2 1.7 3e-87 292.6 1.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO33636.1 - 2.8e-41 140.9 0.0 5.1e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Sec34 PF04136.15 KDO33636.1 - 0.0048 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family T2SSE PF00437.20 KDO33636.1 - 0.0085 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein HALZ PF02183.18 KDO33636.1 - 0.1 12.8 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper NUP50 PF08911.11 KDO33636.1 - 0.13 12.9 0.9 0.44 11.3 0.9 1.9 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Fib_alpha PF08702.10 KDO33636.1 - 1.2 9.3 6.8 0.46 10.6 0.3 3.1 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Syntaxin-18_N PF10496.9 KDO33636.1 - 3.8 7.8 5.8 1.6 9.1 1.4 2.5 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus ABC_membrane PF00664.23 KDO33637.1 - 2.9e-48 164.9 30.3 2.1e-29 103.1 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO33637.1 - 1.4e-43 148.7 0.0 2e-26 93.1 0.0 2.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO33637.1 - 3.8e-13 49.4 2.5 0.005 16.3 0.0 4.2 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO33637.1 - 5.1e-08 32.5 0.1 0.005 16.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO33637.1 - 4.7e-07 29.9 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KDO33637.1 - 4.8e-07 30.5 0.0 0.011 16.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KDO33637.1 - 7.4e-07 29.3 5.6 0.0066 16.3 0.1 3.9 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO33637.1 - 2.7e-06 27.9 1.2 0.013 15.9 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO33637.1 - 4.8e-06 26.6 0.1 0.05 13.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO33637.1 - 1.3e-05 25.5 0.0 0.3 11.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 KDO33637.1 - 0.00033 19.9 0.1 0.53 9.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KDO33637.1 - 0.00053 20.1 1.0 0.36 10.9 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_15 PF13175.6 KDO33637.1 - 0.0008 19.2 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 KDO33637.1 - 0.0011 18.6 0.8 0.15 11.6 0.1 3.3 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KDO33637.1 - 0.0014 18.4 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KDO33637.1 - 0.0017 17.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 KDO33637.1 - 0.0021 18.5 0.0 0.4 11.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KDO33637.1 - 0.0056 15.8 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.6 KDO33637.1 - 0.006 16.8 0.7 2.7 8.3 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KDO33637.1 - 0.0071 15.6 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 KDO33637.1 - 0.022 14.9 0.3 0.47 10.5 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 KDO33637.1 - 0.027 14.7 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO33637.1 - 0.028 15.0 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KDO33637.1 - 0.033 13.0 0.0 4.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 KDO33637.1 - 0.039 13.7 0.2 3.8 7.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KDO33637.1 - 0.048 13.4 0.1 6.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 KDO33637.1 - 0.061 12.7 0.1 7.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 KDO33637.1 - 0.067 12.1 0.1 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain Roc PF08477.13 KDO33637.1 - 0.071 13.3 0.2 16 5.7 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KDO33637.1 - 0.076 12.7 0.5 5.8 6.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO33637.1 - 0.079 13.3 0.0 16 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KDO33637.1 - 0.083 12.9 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 KDO33637.1 - 0.087 12.2 0.1 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KDO33637.1 - 0.13 11.4 0.3 14 4.8 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activat PF00158.26 KDO33637.1 - 0.14 11.9 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2706 PF10913.8 KDO33637.1 - 0.3 10.9 1.3 0.96 9.3 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Aa_trans PF01490.18 KDO33638.1 - 5.1e-37 127.5 31.0 6.6e-37 127.2 31.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAYSvFN PF10260.9 KDO33638.1 - 0.3 11.0 0.1 0.3 11.0 0.1 4.0 5 0 0 5 5 5 0 Uncharacterized conserved domain (SAYSvFN) Pex24p PF06398.11 KDO33638.1 - 4.4 6.2 13.6 0.0084 15.1 2.5 2.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3685 PF12452.8 KDO33639.1 - 0.46 10.1 2.8 0.73 9.5 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) UPRTase PF14681.6 KDO33640.1 - 0.087 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PhnA PF03831.14 KDO33641.1 - 3.2e-20 71.7 0.4 4.7e-20 71.2 0.4 1.3 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 KDO33641.1 - 4.9e-08 32.8 0.6 8.3e-08 32.0 0.6 1.4 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TFIIS_C PF01096.18 KDO33641.1 - 0.085 12.7 1.3 8.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PADR1 PF08063.12 KDO33641.1 - 0.11 12.3 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain Zn-ribbon_8 PF09723.10 KDO33641.1 - 0.13 12.4 1.0 4.9 7.4 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KDO33641.1 - 0.26 11.3 2.3 2.3 8.3 2.8 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-TFIIB PF13453.6 KDO33641.1 - 0.52 9.7 4.6 7.1 6.0 4.6 2.4 1 1 0 1 1 1 0 Transcription factor zinc-finger CTP_transf_like PF01467.26 KDO33642.1 - 1.1e-35 123.0 0.1 3.7e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like DivIC PF04977.15 KDO33642.1 - 0.0006 19.5 0.1 0.0016 18.2 0.1 1.7 1 0 0 1 1 1 1 Septum formation initiator FAD_syn PF06574.12 KDO33642.1 - 0.00078 19.4 0.3 0.34 10.8 0.1 3.4 2 1 0 2 2 2 1 FAD synthetase HR1 PF02185.16 KDO33642.1 - 0.0039 17.3 2.4 0.0097 16.0 2.4 1.6 1 0 0 1 1 1 1 Hr1 repeat T2SSM PF04612.12 KDO33642.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M MHYT PF03707.16 KDO33642.1 - 0.2 11.8 0.7 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat TIP41 PF04176.13 KDO33643.1 - 8.6e-57 191.4 0.3 1.3e-56 190.8 0.1 1.4 2 0 0 2 2 2 1 TIP41-like family FYVE PF01363.21 KDO33644.1 - 2.5e-06 27.5 12.8 5.7e-06 26.4 12.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 KDO33644.1 - 0.028 14.7 7.2 0.028 14.7 7.2 1.9 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.16 KDO33644.1 - 0.19 11.9 10.4 0.33 11.2 10.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger HSF_DNA-bind PF00447.17 KDO33646.1 - 8e-10 39.2 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 KDO33647.1 - 5.4e-20 71.8 0.0 9e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding ApoL PF05461.11 KDO33647.1 - 0.045 13.1 0.2 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein L B56 PF01603.20 KDO33648.1 - 7.3e-175 581.9 0.2 8.5e-175 581.7 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) WW PF00397.26 KDO33649.1 - 2e-51 171.7 24.3 5.8e-09 35.9 0.2 9.2 9 0 0 9 9 9 7 WW domain Ank_2 PF12796.7 KDO33649.1 - 1.4e-38 131.3 17.8 1.5e-11 44.7 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33649.1 - 6.6e-30 103.1 14.3 9e-10 38.9 0.1 8.2 2 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33649.1 - 3.9e-26 90.8 20.1 6.2e-07 29.6 0.1 7.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33649.1 - 1e-22 77.7 16.3 0.023 15.2 0.0 9.7 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KDO33649.1 - 2.5e-22 78.3 24.8 0.0014 19.0 0.4 10.8 11 0 0 11 11 11 6 Ankyrin repeat IQ PF00612.27 KDO33649.1 - 1.3e-16 58.7 107.3 0.00032 20.2 0.5 15.7 16 0 0 16 16 16 11 IQ calmodulin-binding motif PQQ_2 PF13360.6 KDO33649.1 - 8e-07 28.9 7.7 4.6e-05 23.1 3.8 3.3 2 1 0 2 2 2 1 PQQ-like domain Glyco_hyd_101C PF17451.2 KDO33649.1 - 0.0021 18.4 14.2 5.1 7.4 0.1 5.7 3 1 3 6 6 6 2 Glycosyl hydrolase 101 beta sandwich domain RGI1 PF10843.8 KDO33649.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Respiratory growth induced protein 1 PQQ PF01011.21 KDO33649.1 - 0.087 12.8 13.6 3.8 7.6 0.1 5.3 4 1 1 5 5 5 0 PQQ enzyme repeat TPR_2 PF07719.17 KDO33649.1 - 0.14 12.3 1.9 0.96 9.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PDEase_I PF00233.19 KDO33651.1 - 1.2e-63 215.1 0.1 2.3e-63 214.1 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.6 KDO33651.1 - 3.2e-08 34.0 0.0 0.011 16.0 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KDO33651.1 - 0.00014 22.2 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 GAF domain HD PF01966.22 KDO33651.1 - 0.0017 18.6 0.2 0.0065 16.7 0.1 2.0 2 0 0 2 2 2 1 HD domain DUF1192 PF06698.11 KDO33651.1 - 0.35 11.0 1.5 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FlxA PF14282.6 KDO33651.1 - 0.35 10.9 1.1 3.6 7.6 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein EIF_2_alpha PF07541.12 KDO33652.1 - 1.1e-40 138.3 0.1 2.4e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KDO33652.1 - 2.6e-06 27.7 0.0 6.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Ion_trans PF00520.31 KDO33653.1 - 4.6e-29 101.4 13.0 7.1e-29 100.7 13.0 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO33653.1 - 7.1e-19 67.7 0.0 1.5e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO33653.1 - 1.4e-09 37.8 12.5 4.3e-09 36.2 12.5 1.9 1 1 0 1 1 1 1 Ion channel Imm15 PF15561.6 KDO33653.1 - 0.015 15.5 0.2 0.032 14.5 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 15 Ion_trans PF00520.31 KDO33654.1 - 1.3e-29 103.2 7.5 2.7e-29 102.1 7.5 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO33654.1 - 3.1e-12 46.3 1.7 1e-11 44.6 1.7 1.9 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 KDO33654.1 - 9.1e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Tim17 PF02466.19 KDO33655.1 - 1.2e-08 35.3 0.4 2.3e-08 34.4 0.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cullin PF00888.22 KDO33656.1 - 4.3e-181 603.7 0.1 5.1e-181 603.4 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KDO33656.1 - 1.1e-23 83.0 0.8 3e-23 81.6 0.8 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Cas_Cas5d PF09704.10 KDO33656.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) HTH_IclR PF09339.10 KDO33656.1 - 0.022 14.5 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain Pkinase PF00069.25 KDO33657.1 - 3.9e-18 65.8 0.0 6.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO33657.1 - 5e-05 23.3 0.1 0.2 11.6 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO33657.1 - 9.9e-05 21.3 0.0 0.00018 20.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KDO33657.1 - 0.065 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 KDO33657.1 - 0.11 11.8 0.0 0.73 9.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Myosin_head PF00063.21 KDO33658.1 - 6.5e-226 751.7 0.0 1.1e-225 750.9 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KDO33658.1 - 2e-15 56.9 0.0 3.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 KDO33658.1 - 5.6e-11 42.4 2.1 1.2e-10 41.4 2.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger RsgA_GTPase PF03193.16 KDO33658.1 - 0.046 13.6 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KDO33658.1 - 0.15 12.5 2.6 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 KDO33658.1 - 0.76 7.2 13.8 1.1 6.7 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nop53 PF07767.11 KDO33658.1 - 1.2 8.5 19.2 1.8 7.8 19.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 KDO33658.1 - 6.4 6.5 7.4 11 5.7 7.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Oxidored_q2 PF00420.24 KDO33659.1 - 0.016 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PRT_C PF08372.10 KDO33660.1 - 5.6e-07 29.4 0.8 1.7e-06 27.8 0.2 2.0 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal PH PF00169.29 KDO33660.1 - 0.00013 22.4 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF639 PF04842.12 KDO33660.1 - 0.00054 19.4 0.9 0.0019 17.7 0.1 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF639) Pex24p PF06398.11 KDO33660.1 - 0.0018 17.3 1.8 0.11 11.5 0.2 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Reticulon PF02453.17 KDO33660.1 - 0.002 18.1 3.0 0.5 10.3 0.1 2.3 2 0 0 2 2 2 2 Reticulon C2 PF00168.30 KDO33660.1 - 0.02 15.2 0.0 3 8.2 0.0 2.7 2 0 0 2 2 2 0 C2 domain Wzy_C PF04932.15 KDO33660.1 - 0.35 10.5 1.3 0.5 10.0 0.2 1.7 2 0 0 2 2 2 0 O-Antigen ligase Ank PF00023.30 KDO33661.1 - 0.0013 19.1 0.0 0.0041 17.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat BPS PF08947.10 KDO33661.1 - 0.0032 17.2 0.3 0.011 15.6 0.3 1.9 1 0 0 1 1 1 1 BPS (Between PH and SH2) Ank_3 PF13606.6 KDO33661.1 - 0.032 14.8 0.1 0.53 11.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 KDO33661.1 - 0.04 14.3 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO33661.1 - 0.087 13.4 0.0 0.35 11.5 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33661.1 - 0.11 13.2 0.1 0.34 11.6 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) 3HCDH_N PF02737.18 KDO33662.1 - 3.5e-56 189.9 0.1 4.6e-56 189.6 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KDO33662.1 - 1.4e-30 105.7 0.1 2.2e-29 101.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KDO33662.1 - 1e-05 25.8 0.2 1.6e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KDO33662.1 - 0.0067 15.8 0.2 0.011 15.0 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KDO33662.1 - 0.074 12.3 2.1 0.12 11.6 2.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 KDO33662.1 - 0.1 13.2 0.2 0.17 12.5 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1681 PF07933.14 KDO33663.1 - 1.2e-39 135.4 0.0 1.5e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Chorismate_synt PF01264.21 KDO33664.1 - 5.1e-135 449.4 0.0 6.2e-135 449.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase CLASP_N PF12348.8 KDO33665.1 - 2e-17 63.5 0.3 2.8e-17 63.1 0.3 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KDO33665.1 - 0.0045 17.1 0.6 0.44 10.9 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat UbiA PF01040.18 KDO33665.1 - 0.027 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 UbiA prenyltransferase family Cnd1 PF12717.7 KDO33665.1 - 0.051 13.6 0.2 5 7.2 0.1 2.5 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO33665.1 - 0.18 12.4 2.0 12 6.5 0.1 3.3 2 1 1 3 3 3 0 HEAT-like repeat RabGAP-TBC PF00566.18 KDO33666.1 - 6.3e-23 81.6 0.0 1.1e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Thioredoxin PF00085.20 KDO33667.1 - 1e-55 186.1 0.0 7.3e-30 103.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KDO33667.1 - 4.8e-07 30.2 1.1 0.00052 20.4 0.0 2.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KDO33667.1 - 9.4e-06 25.9 0.1 0.45 10.9 0.0 3.8 2 2 2 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KDO33667.1 - 5e-05 22.8 0.4 0.07 12.5 0.1 2.6 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KDO33667.1 - 6.8e-05 23.0 0.1 0.42 10.8 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like LRR19-TM PF15176.6 KDO33667.1 - 0.0027 17.7 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain TraF PF13728.6 KDO33667.1 - 0.011 15.5 0.0 3.9 7.2 0.0 2.6 2 1 0 2 2 2 0 F plasmid transfer operon protein Redoxin PF08534.10 KDO33667.1 - 0.019 14.7 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Redoxin Thioredoxin_9 PF14595.6 KDO33667.1 - 0.023 14.5 0.1 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Pkinase PF00069.25 KDO33668.1 - 5.6e-67 225.9 0.0 6.9e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33668.1 - 1.5e-33 116.2 0.0 2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO33668.1 - 2.2e-06 27.2 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KHA PF11834.8 KDO33668.1 - 8e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Haspin_kinase PF12330.8 KDO33668.1 - 0.027 13.4 0.0 0.22 10.4 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 KDO33668.1 - 0.079 12.5 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KDO33668.1 - 0.19 11.1 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2149 PF09919.9 KDO33669.1 - 0.14 12.5 1.1 0.45 10.8 1.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Utp14 PF04615.13 KDO33669.1 - 1 7.9 28.1 1.3 7.5 28.1 1.1 1 0 0 1 1 1 0 Utp14 protein SRP-alpha_N PF04086.13 KDO33669.1 - 4.6 7.1 32.6 7.7 6.3 32.6 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HAD_SAK_2 PF18143.1 KDO33670.1 - 1.2e-25 90.5 0.0 2.7e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Cation_ATPase_C PF00689.21 KDO33671.1 - 8.5e-48 162.5 2.1 8.5e-48 162.5 2.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO33671.1 - 3.5e-31 108.1 6.1 6e-20 71.5 0.1 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 KDO33671.1 - 1.2e-16 60.6 0.0 3.8e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KDO33671.1 - 1.3e-13 50.4 0.0 2.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KDO33671.1 - 2.3e-07 31.3 0.0 0.025 14.9 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 KDO33671.1 - 2.7e-06 27.7 0.3 7e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 KDO33671.1 - 0.0034 17.2 0.4 0.0063 16.3 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KDO33672.1 - 2.3e-42 144.8 2.3 2.3e-42 144.8 2.3 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KDO33672.1 - 3.8e-20 72.2 0.7 3.8e-20 72.2 0.7 3.4 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 KDO33672.1 - 2e-18 66.3 0.0 4.1e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO33672.1 - 1.8e-14 54.6 0.2 1.7e-13 51.4 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO33672.1 - 6.4e-06 25.8 0.0 1.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO33672.1 - 0.00021 21.2 0.3 0.0067 16.2 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nup192 PF11894.8 KDO33673.1 - 3.6e-82 276.4 1.4 3e-80 270.0 0.7 3.3 2 1 0 2 2 2 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 TRM13 PF05206.14 KDO33675.1 - 3.5e-69 233.3 0.1 3.9e-68 229.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 KDO33675.1 - 3.2e-09 36.4 0.4 3.2e-09 36.4 0.4 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 KDO33675.1 - 1.8e-05 24.5 0.4 3.3e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger S-antigen PF05756.11 KDO33675.1 - 0.037 14.4 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 S-antigen protein Peptidase_M15_4 PF13539.6 KDO33675.1 - 0.14 12.7 0.6 23 5.6 0.1 2.8 2 1 1 3 3 3 0 D-alanyl-D-alanine carboxypeptidase UPF0029 PF01205.19 KDO33676.1 - 2.6e-34 117.7 0.3 3.8e-34 117.2 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KDO33676.1 - 7.5e-15 55.2 0.0 2.3e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 RWD domain Nop14 PF04147.12 KDO33677.1 - 0.0029 15.9 4.4 0.1 10.8 4.0 2.1 2 0 0 2 2 2 2 Nop14-like family YL1 PF05764.13 KDO33677.1 - 0.11 12.6 10.2 0.18 11.9 10.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RR_TM4-6 PF06459.12 KDO33677.1 - 0.15 11.8 2.6 0.24 11.2 2.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KDO33677.1 - 0.26 11.3 8.0 0.41 10.7 8.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4710 PF15828.5 KDO33677.1 - 0.63 10.2 6.8 1.2 9.3 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) CDC45 PF02724.14 KDO33677.1 - 3.1 6.0 8.3 4.5 5.4 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1295 PF06966.12 KDO33680.1 - 5.4e-44 150.5 10.8 7.6e-44 150.0 10.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KDO33680.1 - 0.031 14.7 2.7 0.036 14.5 0.2 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KDO33680.1 - 0.046 13.7 3.2 0.055 13.5 2.0 1.8 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase EGF_2 PF07974.13 KDO33681.1 - 3.1e-20 72.2 94.1 4.9e-05 23.6 2.5 9.9 9 0 0 9 9 9 8 EGF-like domain EGF PF00008.27 KDO33681.1 - 0.01 16.2 80.9 0.018 15.4 9.8 9.3 9 0 0 9 9 9 5 EGF-like domain Peptidase_S74 PF13884.6 KDO33682.1 - 9.3e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Chaperone of endosialidase Jnk-SapK_ap_N PF09744.9 KDO33682.1 - 0.0065 16.7 0.7 0.0097 16.1 0.7 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 KDO33682.1 - 0.0071 16.4 1.0 0.011 15.8 1.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3422 PF11902.8 KDO33682.1 - 0.014 14.5 4.0 0.02 14.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF1993 PF09351.10 KDO33682.1 - 0.1 12.8 1.3 0.15 12.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF4570 PF15134.6 KDO33682.1 - 0.15 12.1 2.4 0.22 11.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CC2-LZ PF16516.5 KDO33682.1 - 0.37 11.2 4.6 0.58 10.5 4.5 1.4 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CLZ PF16526.5 KDO33682.1 - 1.1 9.7 6.7 4 7.9 0.8 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 KDO33682.1 - 6.6 7.4 7.8 91 3.8 6.7 2.4 1 1 1 2 2 2 0 SlyX EGF_2 PF07974.13 KDO33683.1 - 1.5e-09 38.0 49.7 8.3e-05 22.9 4.1 5.8 5 0 0 5 5 5 3 EGF-like domain EGF PF00008.27 KDO33683.1 - 0.0094 16.2 1.5 0.0094 16.2 1.5 6.0 5 2 1 6 6 6 1 EGF-like domain SRP-alpha_N PF04086.13 KDO33684.1 - 0.5 10.2 17.3 0.6 10.0 17.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Di19_C PF14571.6 KDO33684.1 - 0.52 10.9 7.5 0.098 13.2 3.2 1.8 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal Glyco_transf_41 PF13844.6 KDO33685.1 - 1.8e-64 217.9 0.3 8.9e-38 129.9 0.1 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 SCP2 PF02036.17 KDO33685.1 - 5.2e-48 161.7 5.0 2e-24 86.0 0.2 2.7 3 0 0 3 3 2 2 SCP-2 sterol transfer family TPR_1 PF00515.28 KDO33685.1 - 3.2e-16 58.3 5.1 0.0001 22.0 0.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33685.1 - 1.1e-14 53.3 18.5 5.1e-05 23.1 0.5 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33685.1 - 1.6e-11 43.7 7.2 0.003 17.2 0.1 4.8 2 1 2 4 4 4 4 TPR repeat TPR_8 PF13181.6 KDO33685.1 - 3.4e-11 42.4 1.0 0.016 15.3 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Alkyl_sulf_C PF14864.6 KDO33685.1 - 8.4e-11 42.2 1.5 0.00014 22.2 0.1 2.4 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal TPR_14 PF13428.6 KDO33685.1 - 8e-09 35.6 25.5 0.0032 18.2 0.1 6.7 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33685.1 - 2.4e-06 27.5 9.8 1.8 9.1 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33685.1 - 1.7e-05 25.2 20.5 0.0032 17.9 0.2 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33685.1 - 3.7e-05 23.5 2.8 0.31 11.1 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33685.1 - 0.00014 22.1 26.7 0.12 12.7 2.0 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO33685.1 - 0.0003 20.9 15.8 0.0084 16.2 0.7 4.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33685.1 - 0.0058 17.3 35.2 0.14 12.8 5.0 4.9 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33685.1 - 0.019 15.6 6.4 12 6.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 KDO33685.1 - 0.15 11.2 6.6 0.47 9.6 4.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Mod_r PF07200.13 KDO33686.1 - 4.4e-29 101.5 3.2 5.9e-29 101.1 3.2 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 KDO33686.1 - 0.004 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prefoldin_2 PF01920.20 KDO33686.1 - 0.038 13.9 4.0 0.98 9.4 1.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit zf-ANAPC11 PF12861.7 KDO33687.1 - 1.9e-35 120.8 15.6 2.1e-35 120.7 15.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KDO33687.1 - 6.1e-20 71.3 22.3 7.8e-20 70.9 22.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KDO33687.1 - 0.00041 20.6 25.4 0.0043 17.3 25.4 2.1 1 1 0 1 1 1 1 Ring finger domain Rad50_zn_hook PF04423.14 KDO33687.1 - 0.055 13.3 0.4 0.055 13.3 0.4 2.6 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 KDO33687.1 - 0.073 13.0 21.6 0.44 10.5 21.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KDO33687.1 - 0.074 13.2 20.4 0.29 11.3 20.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_47 PF01532.20 KDO33688.1 - 2e-134 449.0 0.0 2.3e-134 448.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M22 PF00814.25 KDO33688.1 - 0.039 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family DUF3586 PF12131.8 KDO33689.1 - 4.2 7.6 13.3 7.8 6.8 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) IMS PF00817.20 KDO33690.1 - 3.9e-43 147.0 0.0 7.9e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KDO33690.1 - 6.3e-10 38.5 1.2 1.4e-09 37.4 1.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KDO33690.1 - 0.00026 21.1 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif LRR_6 PF13516.6 KDO33692.1 - 1.1e-24 84.3 10.9 0.00016 21.5 0.3 9.5 10 0 0 10 10 10 7 Leucine Rich repeat Pyr_redox_2 PF07992.14 KDO33694.1 - 7.2e-45 153.5 0.0 4.2e-44 150.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO33694.1 - 0.017 15.7 1.3 0.58 10.8 0.0 3.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3445 PF11927.8 KDO33694.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) PAN_4 PF14295.6 KDO33695.1 - 1.1e-05 25.2 21.3 0.0024 17.7 1.2 3.7 3 1 0 3 3 3 2 PAN domain Rbx_binding PF18113.1 KDO33695.1 - 0.51 10.2 2.4 0.66 9.8 0.0 2.4 3 0 0 3 3 3 0 Rubredoxin binding C-terminal domain PAN_2 PF08276.11 KDO33695.1 - 1.1 9.4 10.8 0.35 11.0 0.4 2.9 2 0 0 2 2 2 0 PAN-like domain CBM_1 PF00734.18 KDO33696.1 - 3.7e-15 55.6 29.0 1.3e-08 34.6 11.8 3.6 3 0 0 3 3 3 2 Fungal cellulose binding domain PDZ PF00595.24 KDO33697.1 - 1.3e-13 51.1 0.0 3.8e-05 24.0 0.0 4.1 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 KDO33697.1 - 1.9e-11 43.6 0.0 0.00016 21.5 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KDO33697.1 - 7e-05 23.1 0.0 0.034 14.5 0.0 3.4 4 0 0 4 4 4 1 PDZ domain Tricorn_PDZ PF14685.6 KDO33697.1 - 0.14 12.1 0.0 31 4.6 0.0 2.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain NPV_P10 PF05531.12 KDO33698.1 - 0.11 13.0 0.4 0.18 12.3 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nucleoside_tran PF01733.18 KDO33699.1 - 2.7e-25 89.4 12.9 8.3e-25 87.8 12.9 1.8 1 1 0 1 1 1 1 Nucleoside transporter DUF4024 PF13216.6 KDO33699.1 - 0.018 15.0 0.4 0.079 12.9 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) N6-adenineMlase PF10237.9 KDO33700.1 - 3.2e-37 127.8 0.0 3.7e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KDO33700.1 - 0.0067 16.1 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KDO33700.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KDO33700.1 - 0.039 13.8 0.0 0.059 13.2 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Laminin_G_3 PF13385.6 KDO33701.1 - 2.4e-06 27.8 0.0 5.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KDO33701.1 - 0.0067 17.3 0.0 0.083 13.8 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-HC3 PF16827.5 KDO33701.1 - 0.093 13.0 0.5 1.8 8.8 0.1 2.8 2 0 0 2 2 2 0 zinc-finger SapB_2 PF03489.17 KDO33702.1 - 3.8e-21 74.9 24.0 0.00088 19.3 0.0 10.7 11 0 0 11 11 11 8 Saposin-like type B, region 2 DUF1351 PF07083.11 KDO33702.1 - 0.057 13.2 1.4 9.1 6.0 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1351) DUF5572 PF17733.1 KDO33702.1 - 0.11 12.4 0.0 19 5.2 0.0 4.3 5 0 0 5 5 5 0 Family of unknown function (DUF5572) Ank_2 PF12796.7 KDO33703.1 - 6e-39 132.5 0.8 1e-16 61.2 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) FH2 PF02181.23 KDO33703.1 - 1.9e-28 99.7 1.6 2.8e-26 92.5 1.0 2.2 1 1 1 2 2 2 2 Formin Homology 2 Domain Ank_3 PF13606.6 KDO33703.1 - 4.1e-23 78.9 4.6 0.00092 19.5 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KDO33703.1 - 9e-23 80.4 2.5 6.2e-09 36.2 0.4 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO33703.1 - 2.2e-16 59.5 15.5 4.8e-06 26.8 0.4 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KDO33703.1 - 1.6e-13 50.6 7.5 3.5e-05 24.0 0.1 5.5 1 1 5 6 6 6 3 Ankyrin repeats (many copies) WW PF00397.26 KDO33703.1 - 1.2e-06 28.5 2.7 4e-06 26.8 2.7 1.9 1 0 0 1 1 1 1 WW domain PH_12 PF16457.5 KDO33703.1 - 1.9e-05 25.2 0.0 4.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KDO33703.1 - 4.2e-05 24.0 0.1 0.0001 22.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 KDO33703.1 - 0.0023 18.1 0.1 0.0063 16.6 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology C2 PF00168.30 KDO33703.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 C2 domain PH_2 PF08458.10 KDO33703.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region KIAA1430 PF13879.6 KDO33704.1 - 3.5e-26 91.9 13.9 5.7e-26 91.3 13.9 1.3 1 0 0 1 1 1 1 KIAA1430 homologue Phlebovirus_NSM PF07246.11 KDO33704.1 - 1.4 8.2 6.9 1.7 7.9 6.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M RPAP3_C PF13877.6 KDO33705.1 - 1.4e-12 47.9 0.0 5.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Dynein_attach_N PF15867.5 KDO33705.1 - 2e-08 34.0 2.4 3.9e-08 33.1 2.4 1.4 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RhoGAP PF00620.27 KDO33705.1 - 0.052 13.4 0.3 0.32 10.8 0.0 2.2 2 1 0 2 2 2 0 RhoGAP domain DUF2894 PF11445.8 KDO33705.1 - 0.72 10.3 6.6 0.45 11.0 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) LysE PF01810.18 KDO33706.1 - 1.8e-14 53.7 10.0 1.8e-14 53.7 10.0 1.8 2 0 0 2 2 2 1 LysE type translocator MarC PF01914.17 KDO33706.1 - 2.3 7.5 11.5 0.25 10.7 4.8 2.6 2 1 0 2 2 2 0 MarC family integral membrane protein DRIM PF07539.12 KDO33707.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis FA_hydroxylase PF04116.13 KDO33708.1 - 1e-18 67.9 3.2 1.4e-18 67.6 3.2 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 KDO33709.1 - 9e-43 146.5 41.9 1.5e-37 129.3 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO33709.1 - 0.00012 21.1 7.3 0.00012 21.1 7.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.8 KDO33709.1 - 0.00021 20.1 3.9 0.00038 19.2 3.9 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MccV PF17508.2 KDO33709.1 - 2 9.0 11.3 2 9.0 0.1 3.4 3 0 0 3 3 3 0 Microcin V bacteriocin LacY_symp PF01306.19 KDO33709.1 - 2.8 6.6 13.0 0.019 13.8 3.7 1.9 2 1 0 2 2 2 0 LacY proton/sugar symporter TSP_1 PF00090.19 KDO33710.1 - 3.7e-12 46.3 154.0 1.8e-05 24.9 6.0 15.2 13 2 2 15 15 15 10 Thrombospondin type 1 domain PTN_MK_C PF01091.18 KDO33710.1 - 0.00015 22.1 5.5 0.0083 16.5 0.1 13.7 13 4 1 14 14 14 5 PTN/MK heparin-binding protein family, C-terminal domain Atx10homo_assoc PF09759.9 KDO33711.1 - 0.0073 16.3 0.2 0.024 14.6 0.2 1.9 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain NopRA1 PF16201.5 KDO33711.1 - 0.059 13.0 0.1 0.33 10.5 0.0 2.4 2 1 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 PUL PF08324.11 KDO33711.1 - 0.072 12.3 2.4 2.2 7.4 0.1 2.7 3 0 0 3 3 3 0 PUL domain Arm PF00514.23 KDO33711.1 - 0.24 11.5 4.3 18 5.6 0.1 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Peptidase_M16 PF00675.20 KDO33712.1 - 4.2e-23 82.0 0.4 5e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KDO33712.1 - 3.9e-13 49.8 0.0 1.2e-11 45.0 0.0 2.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain DnaJ_C PF01556.18 KDO33713.1 - 1.3e-25 90.2 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KDO33713.1 - 3.9e-10 39.9 13.1 6.5e-10 39.2 13.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KDO33713.1 - 0.0013 18.6 11.0 0.033 14.1 1.8 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KDO33713.1 - 0.068 13.2 6.4 0.42 10.6 0.4 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_CopZ PF18423.1 KDO33713.1 - 0.12 12.3 1.8 6.9 6.7 0.5 2.7 2 0 0 2 2 2 0 Zinc binding domain Lar_restr_allev PF14354.6 KDO33713.1 - 0.13 12.7 9.6 0.079 13.4 3.7 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar Ephrin_rec_like PF07699.13 KDO33713.1 - 0.2 11.5 0.2 0.2 11.5 0.2 1.9 2 1 0 2 2 2 0 Putative ephrin-receptor like zf-C4_Topoisom PF01396.19 KDO33713.1 - 0.34 10.7 1.8 0.91 9.4 1.8 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger FdhE PF04216.12 KDO33713.1 - 1.6 8.5 4.0 2.5 7.9 4.0 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Rsm22 PF09243.10 KDO33714.1 - 7.4e-48 163.2 0.0 5.4e-47 160.3 0.0 2.3 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KDO33714.1 - 2e-09 37.5 0.0 3.2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33714.1 - 5.4e-07 30.3 0.0 1.4e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_34 PF11312.8 KDO33714.1 - 0.11 11.8 0.0 0.53 9.5 0.0 2.0 1 1 1 2 2 2 0 Putative SAM-dependent methyltransferase TP6A_N PF04406.14 KDO33716.1 - 1.2e-16 60.4 0.1 2.3e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prefoldin_3 PF13758.6 KDO33717.1 - 0.0037 17.3 0.8 0.0037 17.3 0.8 2.3 1 1 1 2 2 2 1 Prefoldin subunit Tup_N PF08581.10 KDO33717.1 - 5 7.5 13.2 0.77 10.1 0.6 3.4 2 1 1 3 3 3 0 Tup N-terminal DSPc PF00782.20 KDO33718.1 - 4.6e-22 78.3 0.1 6.8e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO33718.1 - 0.0021 17.6 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KDO33718.1 - 0.0033 17.9 0.0 0.11 13.0 0.0 2.8 2 1 0 2 2 2 1 Rhodanese-like domain DUF442 PF04273.13 KDO33718.1 - 0.017 15.2 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) CheZ PF04344.13 KDO33719.1 - 0.29 11.0 11.0 0.25 11.2 9.1 1.9 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ Fib_alpha PF08702.10 KDO33719.1 - 0.99 9.6 7.1 3.9 7.7 6.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KDO33719.1 - 6.4 7.5 7.1 2.2 9.0 3.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA NHL PF01436.21 KDO33720.1 - 3.4e-27 93.1 37.6 2.7e-05 24.0 0.0 11.9 12 0 0 12 12 12 8 NHL repeat DUF5128 PF17170.4 KDO33720.1 - 0.006 15.8 0.0 0.45 9.6 0.0 3.1 3 0 0 3 3 3 1 6-bladed beta-propeller CCDC66 PF15236.6 KDO33720.1 - 1.1 9.1 16.0 1.9 8.3 16.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 zf-TRM13_CCCH PF11722.8 KDO33721.1 - 0.042 13.6 0.1 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein FA_hydroxylase PF04116.13 KDO33722.1 - 1.5e-30 106.3 19.9 2.2e-30 105.7 14.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KDO33723.1 - 5.8e-30 104.4 15.0 5.8e-30 104.4 15.0 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1418 PF07214.12 KDO33723.1 - 0.74 9.7 3.0 0.75 9.7 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) EGF_Tenascin PF18720.1 KDO33727.1 - 2.8e-05 24.0 4.8 0.00019 21.4 4.9 2.4 2 0 0 2 2 2 1 Tenascin EGF domain KIX_2 PF16987.5 KDO33728.1 - 2.9e-09 36.8 0.5 7.9e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 KIX domain HRDC PF00570.23 KDO33728.1 - 1.2e-08 34.8 0.0 3.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 HRDC domain YabA PF06156.13 KDO33728.1 - 0.07 13.8 0.4 0.17 12.5 0.4 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Fez1 PF06818.15 KDO33728.1 - 0.076 13.5 0.7 0.076 13.5 0.7 1.9 2 0 0 2 2 2 0 Fez1 SlyX PF04102.12 KDO33728.1 - 0.14 12.8 5.5 0.53 10.9 5.5 2.0 1 0 0 1 1 1 0 SlyX Lzipper-MIP1 PF14389.6 KDO33728.1 - 0.16 12.3 2.1 0.63 10.4 0.9 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 KDO33728.1 - 1.4 9.3 3.4 2.6 8.4 1.2 2.6 3 0 0 3 3 3 0 TSC-22/dip/bun family Pkinase PF00069.25 KDO33729.1 - 4e-38 131.3 0.0 2.1e-37 128.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33729.1 - 7.3e-17 61.5 0.0 1.4e-16 60.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KDO33729.1 - 1.1e-05 25.5 4.4 0.0052 16.7 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO33729.1 - 6.7e-05 22.3 0.2 0.00011 21.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KDO33729.1 - 0.0071 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 KDO33729.1 - 0.058 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KDO33729.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KDO33729.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KDO33729.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA PF00004.29 KDO33730.1 - 1.2e-46 158.4 0.0 5.9e-35 120.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO33730.1 - 6e-17 61.2 2.2 4.7e-14 51.9 0.3 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KDO33730.1 - 2.6e-10 41.0 7.7 8.1e-05 23.1 0.2 4.0 2 2 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KDO33730.1 - 1.7e-09 37.6 0.6 1.1e-05 25.2 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_33 PF13671.6 KDO33730.1 - 1.2e-08 35.2 0.1 1.5e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KDO33730.1 - 2.2e-07 30.9 0.0 0.0064 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KDO33730.1 - 2.6e-07 31.2 0.1 0.00034 21.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KDO33730.1 - 1.5e-06 28.6 0.4 0.014 15.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 KDO33730.1 - 2e-06 27.8 0.3 0.00026 21.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KDO33730.1 - 2.3e-06 27.7 0.2 0.00032 20.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KDO33730.1 - 2.7e-06 27.4 3.5 0.026 14.5 0.1 3.5 2 2 0 2 2 2 2 NACHT domain DUF815 PF05673.13 KDO33730.1 - 2.8e-06 26.7 0.1 0.0013 17.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KDO33730.1 - 2.3e-05 24.7 0.0 0.0039 17.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KDO33730.1 - 4.3e-05 23.5 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KDO33730.1 - 6.2e-05 23.3 0.1 0.0084 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KDO33730.1 - 8.5e-05 22.5 0.0 0.49 10.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein RuvB_N PF05496.12 KDO33730.1 - 0.00011 22.0 0.0 0.022 14.5 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KDO33730.1 - 0.00012 22.3 0.0 0.65 10.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 KDO33730.1 - 0.00032 20.6 0.0 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO33730.1 - 0.00033 20.2 0.0 0.047 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 KDO33730.1 - 0.00058 20.4 0.1 0.014 15.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 KDO33730.1 - 0.00091 19.0 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KDO33730.1 - 0.0017 17.8 0.8 0.72 9.2 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KDO33730.1 - 0.0019 18.1 0.7 0.13 12.2 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase DUF853 PF05872.12 KDO33730.1 - 0.0024 16.6 0.0 0.038 12.6 0.1 2.5 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF853) AAA_29 PF13555.6 KDO33730.1 - 0.0024 17.6 0.7 0.16 11.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KDO33730.1 - 0.003 17.2 0.4 0.11 12.0 0.1 2.8 2 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 KDO33730.1 - 0.0045 16.9 0.9 0.015 15.2 0.1 2.0 2 1 0 2 2 2 1 Rad17 P-loop domain AFG1_ATPase PF03969.16 KDO33730.1 - 0.0046 15.9 0.0 0.94 8.3 0.0 2.4 2 1 0 2 2 2 1 AFG1-like ATPase MobB PF03205.14 KDO33730.1 - 0.0054 16.6 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KDO33730.1 - 0.0068 16.3 0.2 0.76 9.7 0.0 2.4 2 0 0 2 2 2 1 NTPase TIP49 PF06068.13 KDO33730.1 - 0.007 15.6 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 KDO33730.1 - 0.008 15.9 0.0 0.089 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KDO33730.1 - 0.0082 16.2 0.2 0.43 10.6 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 KDO33730.1 - 0.01 15.6 0.5 0.25 11.1 0.0 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 KDO33730.1 - 0.018 15.5 0.0 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KDO33730.1 - 0.03 13.9 0.2 1 9.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 KDO33730.1 - 0.034 13.6 0.2 0.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 KDO33730.1 - 0.034 13.8 0.2 2.8 7.6 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KDO33730.1 - 0.037 13.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KDO33730.1 - 0.049 14.1 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KDO33730.1 - 0.062 12.6 0.2 8.6 5.6 0.0 2.6 2 1 0 2 2 2 0 KaiC CBP_BcsQ PF06564.12 KDO33730.1 - 0.063 12.7 0.3 0.33 10.4 0.2 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_21 PF13304.6 KDO33730.1 - 0.075 12.8 0.1 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KDO33730.1 - 0.079 12.5 0.7 3.9 7.0 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 KDO33730.1 - 0.085 12.0 0.1 7.9 5.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Zeta_toxin PF06414.12 KDO33730.1 - 0.087 12.1 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin NB-ARC PF00931.22 KDO33730.1 - 0.11 11.7 0.4 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 KDO33730.1 - 0.13 12.1 0.0 5.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 KDO33730.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein APS_kinase PF01583.20 KDO33730.1 - 0.2 11.6 0.3 12 5.8 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Robl_LC7 PF03259.17 KDO33731.1 - 3.8e-08 33.0 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain RdRP PF05183.12 KDO33732.1 - 2.5e-138 462.3 0.0 3.1e-138 462.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Cytochrom_B558a PF05038.13 KDO33732.1 - 0.13 11.8 0.5 0.31 10.6 0.5 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit EF-hand_1 PF00036.32 KDO33733.1 - 7.6e-42 137.8 14.2 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO33733.1 - 1e-35 122.0 3.4 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO33733.1 - 1.6e-32 111.1 12.1 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KDO33733.1 - 2.2e-30 101.9 7.7 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO33733.1 - 8.7e-27 91.4 10.5 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KDO33733.1 - 2.2e-16 59.9 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KDO33733.1 - 7.2e-10 38.8 0.8 0.00014 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KDO33733.1 - 2e-08 34.5 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KDO33733.1 - 4.2e-07 30.8 0.0 0.00016 22.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KDO33733.1 - 8.7e-06 25.7 0.9 0.042 13.9 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KDO33733.1 - 6.4e-05 23.0 1.0 0.00037 20.5 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KDO33733.1 - 0.00027 21.0 3.9 0.045 13.9 0.3 2.8 1 1 0 2 2 2 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 KDO33733.1 - 0.0013 19.0 0.4 0.73 10.2 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 KDO33733.1 - 0.0017 18.3 0.3 0.58 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1103 PF06513.11 KDO33733.1 - 0.0019 17.9 2.1 0.0022 17.7 2.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 KDO33733.1 - 0.0019 18.9 0.4 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 KDO33733.1 - 0.0024 17.8 1.4 0.49 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 KDO33733.1 - 0.0074 14.9 0.0 0.0074 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF853 PF05872.12 KDO33733.1 - 0.022 13.4 0.1 0.6 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 KDO33733.1 - 0.028 14.6 0.1 4.1 7.7 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 KDO33733.1 - 0.029 14.2 0.6 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KDO33733.1 - 0.035 14.2 0.4 0.54 10.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KDO33733.1 - 0.047 12.9 0.1 3.8 6.6 0.1 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 KDO33733.1 - 0.061 13.0 1.0 0.24 11.0 1.0 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 KDO33733.1 - 0.075 13.4 0.2 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 KDO33733.1 - 0.27 11.3 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 AMP-binding PF00501.28 KDO33734.1 - 7.5e-101 337.8 0.1 8.9e-101 337.5 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO33734.1 - 1.1e-18 68.0 0.1 3.2e-18 66.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 KDO33734.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain WW PF00397.26 KDO33735.1 - 2.4e-06 27.5 2.0 5.4e-06 26.4 2.0 1.7 1 0 0 1 1 1 1 WW domain FAIM1 PF06905.13 KDO33735.1 - 0.0018 18.0 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 Fas apoptotic inhibitory molecule (FAIM1) Mob1_phocein PF03637.17 KDO33736.1 - 5.9e-74 247.7 0.0 7e-74 247.4 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Methyltransf_11 PF08241.12 KDO33737.1 - 2.1e-06 28.3 0.1 7.4e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33737.1 - 1.1e-05 26.0 0.1 4.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33737.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain KELK PF15796.5 KDO33739.1 - 0.095 13.2 3.9 1.4 9.4 0.5 2.6 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Matrilin_ccoil PF10393.9 KDO33739.1 - 0.35 10.8 1.7 7.8 6.5 0.1 2.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin AraC_binding_2 PF14525.6 KDO33740.1 - 0.022 14.4 0.8 0.029 14.0 0.8 1.2 1 0 0 1 1 1 0 AraC-binding-like domain LMBR1 PF04791.16 KDO33740.1 - 0.34 9.8 5.3 0.35 9.7 5.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Med9 PF07544.13 KDO33740.1 - 0.41 10.8 9.4 0.83 9.8 8.9 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF349 PF03993.12 KDO33740.1 - 1.9 8.8 11.8 0.65 10.3 7.8 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Macoilin PF09726.9 KDO33740.1 - 3.2 6.2 13.7 3.2 6.2 13.7 1.0 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 KDO33740.1 - 4.7 6.7 13.5 5.1 6.6 13.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Anoctamin PF04547.12 KDO33741.1 - 5e-77 259.7 10.5 5e-77 259.7 10.5 2.1 2 0 0 2 2 2 1 Calcium-activated chloride channel Tetraspanin PF00335.20 KDO33741.1 - 1.4 8.6 13.3 3.7 7.2 4.4 3.0 2 0 0 2 2 2 0 Tetraspanin family UPF0242 PF06785.11 KDO33742.1 - 0.0019 18.4 10.7 0.0019 18.4 10.7 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF421 PF04239.12 KDO33742.1 - 0.032 14.0 1.6 0.072 12.9 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Suppressor_APC PF11414.8 KDO33742.1 - 0.75 9.9 12.9 0.42 10.7 1.7 3.2 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF4407 PF14362.6 KDO33742.1 - 0.79 9.0 11.6 0.49 9.7 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 KDO33742.1 - 3.1 7.1 25.2 0.58 9.5 13.8 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KDO33742.1 - 3.8 7.8 20.1 2.4 8.4 0.5 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PI3K_P85_iSH2 PF16454.5 KDO33742.1 - 8.1 6.0 22.7 0.38 10.3 4.9 3.3 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SPRY PF00622.28 KDO33743.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 SPRY domain zf-C3HC PF07967.13 KDO33744.1 - 1.1e-25 90.2 4.5 6.5e-22 78.0 0.6 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KDO33744.1 - 9e-05 22.6 0.7 9e-05 22.6 0.7 2.6 2 1 0 2 2 2 1 Rsm1-like PMSI1 PF15322.6 KDO33744.1 - 0.0071 15.8 0.9 0.013 15.0 0.9 1.4 1 0 0 1 1 1 1 Protein missing in infertile sperm 1, putative Cpn60_TCP1 PF00118.24 KDO33745.1 - 3.9e-157 523.8 6.1 4.5e-157 523.6 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ISN1 PF06437.11 KDO33745.1 - 0.041 12.8 0.1 0.069 12.0 0.1 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase FMN_dh PF01070.18 KDO33746.1 - 1.4e-132 441.9 0.1 1.6e-132 441.8 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KDO33746.1 - 7.2e-05 21.9 0.1 0.00017 20.7 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KDO33746.1 - 0.00084 18.7 0.8 0.17 11.2 0.5 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KDO33746.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF1031 PF06275.11 KDO33746.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) His_biosynth PF00977.21 KDO33746.1 - 0.061 12.8 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 KDO33746.1 - 0.15 11.4 0.0 0.5 9.8 0.0 1.9 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NAD_binding_10 PF13460.6 KDO33747.1 - 3.8e-13 49.7 1.3 5.3e-13 49.3 1.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KDO33747.1 - 1.8e-06 28.0 0.3 3.5e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KDO33747.1 - 5.7e-05 23.5 0.1 9.6e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KDO33747.1 - 0.00019 21.0 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KDO33747.1 - 0.00041 19.9 0.5 0.00062 19.3 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KDO33747.1 - 0.00053 19.6 0.4 0.00088 18.9 0.4 1.4 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KDO33747.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KDO33747.1 - 0.002 18.3 0.1 0.0039 17.3 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KDO33747.1 - 0.0036 16.5 0.0 0.0089 15.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO33747.1 - 0.0068 15.5 0.0 0.017 14.2 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KDO33747.1 - 0.023 13.7 0.1 0.11 11.5 0.0 2.0 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RHH_6 PF16762.5 KDO33747.1 - 0.053 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain NAD_binding_4 PF07993.12 KDO33747.1 - 0.057 12.6 0.1 0.47 9.6 0.0 2.3 2 1 1 3 3 3 0 Male sterility protein GFO_IDH_MocA PF01408.22 KDO33747.1 - 0.076 13.8 0.1 0.11 13.3 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF4604 PF15377.6 KDO33748.1 - 0.013 16.0 17.7 0.092 13.2 17.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) CDC45 PF02724.14 KDO33748.1 - 1.3 7.3 5.7 1.5 7.1 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DAHP_synth_2 PF01474.16 KDO33749.1 - 2.4e-194 645.9 0.0 2.7e-194 645.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family ABC_membrane PF00664.23 KDO33750.1 - 1.8e-114 382.0 28.3 7e-62 209.6 4.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO33750.1 - 7.3e-74 246.8 0.2 2.4e-37 128.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO33750.1 - 1.2e-16 60.8 0.0 4.7e-06 26.2 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO33750.1 - 3.8e-10 40.2 0.7 0.0013 19.1 0.2 3.5 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KDO33750.1 - 1.9e-08 33.5 2.6 0.0091 14.8 0.0 3.5 3 1 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KDO33750.1 - 5.5e-08 32.9 0.1 0.028 14.4 0.1 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KDO33750.1 - 9.6e-08 32.6 0.8 0.0066 16.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO33750.1 - 2e-07 30.7 0.0 0.0044 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KDO33750.1 - 6.3e-07 29.9 2.5 0.25 11.8 0.3 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO33750.1 - 1.3e-05 24.8 0.5 1.5 8.3 0.0 4.3 5 0 0 5 5 4 1 AAA domain APS_kinase PF01583.20 KDO33750.1 - 3.2e-05 23.9 0.1 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.14 KDO33750.1 - 3.4e-05 23.9 1.9 0.12 12.4 0.3 4.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO33750.1 - 7.1e-05 22.6 5.0 0.14 11.8 0.7 3.7 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KDO33750.1 - 0.00016 21.8 3.6 0.8 10.0 0.5 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO33750.1 - 0.00043 20.5 0.1 1.3 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KDO33750.1 - 0.00054 19.5 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KDO33750.1 - 0.00056 20.1 0.4 0.061 13.4 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain G-alpha PF00503.20 KDO33750.1 - 0.00087 18.5 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit DEAD PF00270.29 KDO33750.1 - 0.0012 18.6 2.8 0.094 12.5 0.3 3.4 2 2 0 2 2 2 1 DEAD/DEAH box helicase AAA_15 PF13175.6 KDO33750.1 - 0.0016 18.2 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KDO33750.1 - 0.0024 18.1 0.2 2.1 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KDO33750.1 - 0.0027 17.4 0.0 2.5 7.7 0.0 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KDO33750.1 - 0.0044 16.8 1.6 8.3 6.1 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_18 PF13238.6 KDO33750.1 - 0.0053 17.3 0.0 8 7.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO33750.1 - 0.007 15.7 0.1 0.64 9.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.15 KDO33750.1 - 0.015 15.2 0.1 0.86 9.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain KAP_NTPase PF07693.14 KDO33750.1 - 0.018 14.3 0.0 2.1 7.5 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 KDO33750.1 - 0.019 14.1 0.0 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KDO33750.1 - 0.023 15.2 0.1 5.9 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KDO33750.1 - 0.026 14.9 0.3 15 6.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase PRK PF00485.18 KDO33750.1 - 0.027 14.2 0.1 7 6.3 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MoaE PF02391.17 KDO33750.1 - 0.044 14.0 2.5 2.8 8.2 0.1 3.0 3 0 0 3 3 2 0 MoaE protein TniB PF05621.11 KDO33750.1 - 0.047 13.1 0.1 6.8 6.1 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein AAA_24 PF13479.6 KDO33750.1 - 0.049 13.3 0.3 2.2 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain ECH_2 PF16113.5 KDO33750.1 - 0.056 12.9 0.3 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Mg_chelatase PF01078.21 KDO33750.1 - 0.098 12.0 0.0 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KDO33750.1 - 0.11 12.3 0.0 6.7 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KDO33750.1 - 0.14 12.2 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KDO33750.1 - 0.15 12.0 2.9 2.3 8.1 0.1 3.4 4 0 0 4 4 3 0 NACHT domain ATP-synt_ab PF00006.25 KDO33750.1 - 0.31 10.7 1.7 4.3 6.9 0.0 3.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_membrane PF00664.23 KDO33751.1 - 1e-107 359.9 25.5 9.7e-59 199.2 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO33751.1 - 8.2e-74 246.6 0.2 2.4e-37 128.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO33751.1 - 1.7e-14 53.8 6.8 1.2e-05 24.9 1.1 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO33751.1 - 3.6e-10 40.3 0.7 0.0013 19.1 0.2 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KDO33751.1 - 5.6e-09 35.3 1.7 0.0091 14.8 0.0 3.5 3 1 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KDO33751.1 - 5.1e-08 33.0 0.0 0.024 14.6 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KDO33751.1 - 6.9e-08 33.1 0.7 0.005 17.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO33751.1 - 1.7e-07 30.9 0.0 0.004 16.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KDO33751.1 - 1.4e-06 28.7 4.0 0.25 11.8 0.3 4.5 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO33751.1 - 2.5e-05 24.0 0.8 2.2 7.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.20 KDO33751.1 - 2.8e-05 24.1 0.1 0.31 10.9 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.14 KDO33751.1 - 3.9e-05 23.7 2.2 0.12 12.3 0.4 4.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO33751.1 - 5.2e-05 23.0 5.0 0.14 11.8 0.7 4.0 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KDO33751.1 - 0.00016 21.9 3.6 0.8 10.0 0.5 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO33751.1 - 0.0004 20.6 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KDO33751.1 - 0.00057 20.0 0.4 0.061 13.4 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_7 PF12775.7 KDO33751.1 - 0.00071 19.1 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DEAD PF00270.29 KDO33751.1 - 0.00088 19.1 2.6 0.087 12.6 0.3 3.6 2 2 0 2 2 2 1 DEAD/DEAH box helicase G-alpha PF00503.20 KDO33751.1 - 0.00088 18.5 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit IstB_IS21 PF01695.17 KDO33751.1 - 0.0018 18.0 0.8 8.2 6.1 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 KDO33751.1 - 0.002 17.8 0.1 2.5 7.7 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KDO33751.1 - 0.0023 18.2 0.2 2 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KDO33751.1 - 0.0024 17.7 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KDO33751.1 - 0.006 15.9 0.1 0.57 9.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KDO33751.1 - 0.007 16.9 0.0 7.9 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KDO33751.1 - 0.0083 16.1 0.1 0.88 9.5 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain MoaE PF02391.17 KDO33751.1 - 0.012 15.9 0.5 2.8 8.2 0.1 2.9 2 0 0 2 2 2 0 MoaE protein DUF815 PF05673.13 KDO33751.1 - 0.019 14.1 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 KDO33751.1 - 0.026 14.3 0.1 7 6.3 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KDO33751.1 - 0.026 15.0 0.0 6.5 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KDO33751.1 - 0.037 13.3 0.0 4.3 6.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain TniB PF05621.11 KDO33751.1 - 0.042 13.3 0.1 6.8 6.1 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 KDO33751.1 - 0.044 14.2 0.0 15 6.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KDO33751.1 - 0.044 13.5 0.3 2.2 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain ECH_2 PF16113.5 KDO33751.1 - 0.057 12.9 0.3 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Mg_chelatase PF01078.21 KDO33751.1 - 0.096 12.1 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KDO33751.1 - 0.11 12.2 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 KDO33751.1 - 0.11 12.2 0.0 6.7 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KDO33751.1 - 0.13 12.4 0.1 3.1 7.9 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KDO33751.1 - 0.17 11.8 2.9 2.3 8.1 0.1 3.3 4 0 0 4 4 3 0 NACHT domain ATP-synt_ab PF00006.25 KDO33751.1 - 0.42 10.2 1.8 4.3 6.9 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_membrane PF00664.23 KDO33753.1 - 7.4e-108 360.3 32.0 8.8e-61 205.9 6.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO33753.1 - 1.4e-73 245.9 0.2 2.4e-37 128.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO33753.1 - 2.6e-13 49.9 10.7 9.6e-06 25.2 0.1 4.2 3 2 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO33753.1 - 1.6e-10 41.4 0.4 0.0013 19.0 0.2 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KDO33753.1 - 2.2e-08 33.3 2.8 0.0092 14.8 0.0 3.4 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KDO33753.1 - 4.2e-08 33.8 0.9 0.0066 16.8 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO33753.1 - 9e-08 32.2 0.1 0.025 14.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO33753.1 - 2.3e-07 30.5 0.0 0.0044 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KDO33753.1 - 6e-07 30.0 2.6 0.25 11.8 0.3 4.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO33753.1 - 1.9e-05 24.4 1.0 1.8 8.1 0.0 4.4 5 0 0 5 5 5 1 AAA domain APS_kinase PF01583.20 KDO33753.1 - 2.1e-05 24.5 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.14 KDO33753.1 - 3.2e-05 24.0 2.0 0.12 12.4 0.3 4.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KDO33753.1 - 6.9e-05 22.7 5.3 0.14 11.8 0.7 3.9 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KDO33753.1 - 0.00018 21.7 3.7 0.81 10.0 0.5 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO33753.1 - 0.00023 21.4 0.1 1.3 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KDO33753.1 - 0.00065 19.9 1.1 0.062 13.4 0.1 3.3 3 1 1 4 4 4 1 Helicase HerA, central domain AAA_7 PF12775.7 KDO33753.1 - 0.00075 19.1 0.1 1.4 8.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 KDO33753.1 - 0.00097 18.4 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DEAD PF00270.29 KDO33753.1 - 0.0012 18.6 2.7 0.094 12.5 0.3 3.4 2 2 0 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.6 KDO33753.1 - 0.0019 18.4 0.2 2.1 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KDO33753.1 - 0.0023 17.7 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KDO33753.1 - 0.0033 16.8 0.1 0.64 9.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 KDO33753.1 - 0.0045 16.8 1.5 8.9 6.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 KDO33753.1 - 0.0048 16.5 0.2 2.5 7.7 0.0 2.7 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KDO33753.1 - 0.0078 16.8 0.0 8.5 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO33753.1 - 0.012 14.8 0.0 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KDO33753.1 - 0.018 15.0 0.1 0.92 9.4 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain MoaE PF02391.17 KDO33753.1 - 0.023 15.0 2.1 2.8 8.2 0.1 3.3 3 0 0 3 3 2 0 MoaE protein PRK PF00485.18 KDO33753.1 - 0.023 14.4 0.1 6.5 6.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KDO33753.1 - 0.025 15.1 0.0 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KDO33753.1 - 0.038 13.2 0.0 4.6 6.4 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain TniB PF05621.11 KDO33753.1 - 0.046 13.1 0.1 6.8 6.0 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 KDO33753.1 - 0.051 14.0 0.0 17 5.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KDO33753.1 - 0.052 13.3 0.4 2.2 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain ECH_2 PF16113.5 KDO33753.1 - 0.053 13.0 0.4 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Mg_chelatase PF01078.21 KDO33753.1 - 0.099 12.0 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KDO33753.1 - 0.12 12.2 0.0 6.8 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KDO33753.1 - 0.13 12.3 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KDO33753.1 - 0.16 11.9 2.9 2.3 8.1 0.1 3.4 4 0 0 4 4 3 0 NACHT domain Roc PF08477.13 KDO33753.1 - 0.16 12.2 0.0 29 4.9 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 KDO33753.1 - 0.5 10.0 2.4 4.5 6.9 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Thioredoxin PF00085.20 KDO33754.1 - 1.1e-08 35.0 0.6 3.5e-08 33.4 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Evr1_Alr PF04777.13 KDO33754.1 - 2.6e-06 27.8 1.6 6.6e-06 26.5 1.6 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Zn_Tnp_IS1595 PF12760.7 KDO33754.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RBFA PF02033.18 KDO33755.1 - 1e-11 45.2 0.0 1.8e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A DUF3668 PF12416.8 KDO33755.1 - 0.058 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Cep120 protein LINES_N PF14694.6 KDO33756.1 - 1e-05 25.2 0.3 2.6e-05 23.9 0.2 1.7 1 1 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 KDO33756.1 - 0.00022 20.6 0.1 0.00066 19.1 0.1 1.8 1 0 0 1 1 1 1 Lines C-terminus ThrE PF06738.12 KDO33757.1 - 0.11 11.8 0.1 1 8.7 0.0 2.0 1 1 1 2 2 2 0 Putative threonine/serine exporter Amidase PF01425.21 KDO33758.1 - 2.2e-129 432.3 0.1 2.8e-129 432.0 0.1 1.1 1 0 0 1 1 1 1 Amidase LRR_6 PF13516.6 KDO33759.1 - 1.2e-12 46.7 19.0 0.0084 16.1 0.1 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KDO33759.1 - 1.9e-09 37.7 2.7 0.012 16.1 0.7 4.8 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO33759.1 - 3.5e-06 26.8 6.9 7 7.6 0.1 6.9 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 KDO33759.1 - 7.4e-06 25.6 7.4 0.085 12.6 2.4 4.9 3 1 2 5 5 5 3 Leucine rich repeat Inhibitor_I68 PF10468.9 KDO33759.1 - 0.098 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 LRR_12 PF18837.1 KDO33759.1 - 0.11 12.1 0.2 0.68 9.6 0.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeat LRR_9 PF14580.6 KDO33759.1 - 0.17 11.3 0.1 0.39 10.2 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat EF-hand_8 PF13833.6 KDO33760.1 - 1.3e-14 53.7 3.5 2e-06 27.5 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO33760.1 - 2e-12 45.9 15.8 0.0024 17.7 0.0 6.8 6 1 1 7 7 7 3 EF-hand domain EF-hand_1 PF00036.32 KDO33760.1 - 2.1e-12 45.6 14.8 0.00062 19.1 0.1 6.5 7 0 0 7 7 6 4 EF hand EF-hand_7 PF13499.6 KDO33760.1 - 2.5e-12 47.1 6.6 0.0067 16.9 0.1 5.0 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO33760.1 - 1.8e-05 24.0 2.5 0.14 11.7 0.2 5.0 5 0 0 5 5 5 1 EF hand EF-hand_4 PF12763.7 KDO33760.1 - 0.019 14.9 0.6 8.8 6.3 0.0 3.5 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand MvaI_BcnI PF15515.6 KDO33760.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family IBB PF01749.20 KDO33760.1 - 0.25 11.8 0.1 0.25 11.8 0.1 2.5 2 0 0 2 2 2 0 Importin beta binding domain Histone_HNS PF00816.21 KDO33760.1 - 0.34 11.8 2.9 36 5.3 0.0 3.8 3 1 1 4 4 4 0 H-NS histone family DUF1771 PF08590.10 KDO33760.1 - 0.37 11.2 2.5 0.43 11.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DUF1387 PF07139.11 KDO33760.1 - 4.3 7.0 9.1 13 5.4 9.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ArAE_2 PF10334.9 KDO33761.1 - 0.12 12.1 0.2 0.33 10.7 0.2 1.6 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 MAT1 PF06391.13 KDO33762.1 - 1.6e-24 86.9 18.9 2.1e-24 86.5 18.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KDO33762.1 - 0.00068 19.5 5.2 0.0016 18.3 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) F-actin_cap_A PF01267.17 KDO33762.1 - 0.01 15.3 2.1 0.019 14.4 2.1 1.4 1 0 0 1 1 1 0 F-actin capping protein alpha subunit zf-C3HC4 PF00097.25 KDO33762.1 - 0.014 15.3 10.5 0.024 14.5 10.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_pol3_chi PF04364.13 KDO33762.1 - 0.045 13.9 3.7 0.057 13.6 0.2 2.2 1 1 1 2 2 2 0 DNA polymerase III chi subunit, HolC zf-RING_2 PF13639.6 KDO33762.1 - 0.061 13.7 9.5 0.11 12.8 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KDO33762.1 - 0.065 13.3 6.2 0.12 12.4 6.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger IBR PF01485.21 KDO33762.1 - 0.41 10.9 11.0 3.9 7.8 0.4 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KDO33762.1 - 0.68 9.9 14.1 3.6 7.6 14.4 2.0 1 1 1 2 2 2 0 zinc-RING finger domain PAPS_reduct PF01507.19 KDO33762.1 - 1.3 9.1 4.8 1.9 8.5 4.8 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zf-C3HC4_2 PF13923.6 KDO33762.1 - 2.1 8.2 11.9 5.2 7.0 11.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO33762.1 - 2.4 7.8 10.1 6.9 6.4 10.1 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO33762.1 - 3.3 7.7 8.5 6.5 6.7 8.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 APC_rep PF18797.1 KDO33762.1 - 4.7 8.2 9.5 8 7.5 3.6 3.4 2 1 1 3 3 3 0 Adenomatous polyposis coli (APC) repeat Opiods_neuropep PF01160.18 KDO33763.1 - 0.13 12.4 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Inh PF02974.14 KDO33763.1 - 0.21 11.7 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 Protease inhibitor Inh Methyltransf_16 PF10294.9 KDO33764.1 - 3.7e-13 49.6 0.0 5.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KDO33764.1 - 3e-08 33.6 0.0 4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO33764.1 - 2.2e-06 27.6 0.0 3.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO33764.1 - 6e-06 26.9 0.0 1.2e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO33764.1 - 0.00011 22.8 0.0 0.00027 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO33764.1 - 0.00068 20.3 0.0 0.0016 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO33764.1 - 0.011 15.3 0.0 0.048 13.2 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase small domain FMN_red PF03358.15 KDO33764.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase SET PF00856.28 KDO33765.1 - 2.4e-09 37.8 0.0 3.5e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KDO33765.1 - 0.055 14.1 0.0 7.8 7.2 0.0 2.3 2 0 0 2 2 2 0 SAF domain Amino_oxidase PF01593.24 KDO33766.1 - 4e-18 65.9 0.0 9.9e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KDO33766.1 - 1.7e-14 53.8 0.0 3.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO33766.1 - 2.1e-11 43.6 0.4 8.8e-07 28.4 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO33766.1 - 1.1e-09 38.4 0.3 1.2e-06 28.4 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO33766.1 - 1.2e-07 31.2 0.2 1.9e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KDO33766.1 - 3e-07 30.6 0.6 0.028 14.4 0.0 2.7 3 0 0 3 3 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KDO33766.1 - 9.7e-07 28.5 0.2 1.8e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO33766.1 - 0.00022 20.1 0.5 0.015 14.1 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KDO33766.1 - 0.00047 20.7 1.4 0.042 14.4 0.5 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KDO33766.1 - 0.00071 18.9 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KDO33766.1 - 0.0031 16.7 1.2 0.0062 15.7 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KDO33766.1 - 0.0061 15.7 3.8 0.79 8.7 0.3 2.9 2 1 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KDO33766.1 - 0.0062 15.4 0.1 2.2 7.0 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase ApbA PF02558.16 KDO33766.1 - 0.018 14.7 0.2 0.07 12.8 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KDO33766.1 - 0.053 13.1 0.3 0.085 12.4 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Flavi_NS2B PF01002.19 KDO33766.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Pyr_redox_3 PF13738.6 KDO33766.1 - 0.076 12.2 1.7 0.36 10.0 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.11 KDO33766.1 - 0.11 12.4 0.2 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) FAD_binding_3 PF01494.19 KDO33766.1 - 0.14 11.4 0.6 0.37 10.0 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KDO33766.1 - 0.17 11.7 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CTC1 PF15489.6 KDO33767.1 - 8.4e-12 43.5 8.0 8e-08 30.3 1.8 2.9 2 1 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 CTC1_2 PF15491.6 KDO33767.1 - 0.14 11.5 0.0 1.6 8.0 0.0 2.5 3 0 0 3 3 3 0 CST, telomere maintenance, complex subunit CTC1 KIX_2 PF16987.5 KDO33769.1 - 0.0042 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 KDO33769.1 - 0.091 13.0 0.3 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 KIX domain PAP_central PF04928.17 KDO33770.1 - 4.8e-71 238.6 0.0 9.2e-71 237.7 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KDO33770.1 - 0.00033 20.3 0.0 0.0074 15.9 0.0 2.4 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KDO33770.1 - 0.0026 18.0 0.0 0.0052 17.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KDO33770.1 - 0.039 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF4269 PF14091.6 KDO33770.1 - 0.062 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DUF3498 PF12004.8 KDO33770.1 - 0.66 9.1 7.7 0.97 8.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Dicty_REP PF05086.12 KDO33770.1 - 5.6 4.8 6.1 7.8 4.3 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.22 KDO33772.1 - 7.6e-40 136.2 0.1 9.2e-40 135.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO33772.1 - 8.1e-20 71.2 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO33772.1 - 7e-09 35.4 0.2 8.9e-09 35.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO33772.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain WD40 PF00400.32 KDO33773.1 - 6.3e-17 61.6 13.3 0.00032 21.5 0.3 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO33773.1 - 3.7e-14 52.8 5.2 0.00066 19.9 0.1 7.0 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KDO33773.1 - 0.00019 20.6 4.0 0.052 12.6 0.1 4.1 4 1 0 4 4 4 2 Coatomer WD associated region IKI3 PF04762.12 KDO33773.1 - 0.0027 15.8 0.4 1.7 6.5 0.0 3.1 2 1 1 3 3 3 2 IKI3 family Ge1_WD40 PF16529.5 KDO33773.1 - 0.083 11.8 0.0 8.1 5.3 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 KDO33773.1 - 0.24 10.1 0.7 4.5 5.9 0.0 3.2 5 0 0 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pkinase PF00069.25 KDO33774.1 - 1.1e-67 228.2 0.0 1.5e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33774.1 - 6.6e-36 123.9 0.0 1.6e-35 122.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO33774.1 - 1.4e-05 25.6 0.0 3.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KDO33774.1 - 0.00042 20.7 0.0 0.00091 19.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SnoaL_2 PF12680.7 KDO33774.1 - 0.0078 16.8 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain Kdo PF06293.14 KDO33774.1 - 0.015 14.6 0.3 0.028 13.7 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO33774.1 - 0.02 13.7 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO33774.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KDO33774.1 - 0.058 12.3 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain NUDIX PF00293.28 KDO33775.1 - 1.4e-16 60.7 0.1 2e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain TPR_16 PF13432.6 KDO33778.1 - 0.0077 16.9 8.3 0.47 11.1 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33778.1 - 0.026 15.3 12.1 2 9.5 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.21 KDO33780.1 - 5.5e-48 163.8 0.0 7.7e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KDO33780.1 - 4.1e-41 139.9 0.0 8.5e-41 138.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KDO33780.1 - 0.046 14.2 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.19 KDO33780.1 - 0.11 11.3 0.0 0.24 10.1 0.0 1.5 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase PEX11 PF05648.14 KDO33781.1 - 3.8e-33 114.8 0.9 4.2e-33 114.7 0.9 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lzipper-MIP1 PF14389.6 KDO33781.1 - 0.16 12.2 0.2 0.36 11.2 0.2 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 BET PF17035.5 KDO33782.1 - 4.1e-17 62.1 0.3 9.7e-17 60.9 0.3 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Kelch_5 PF13854.6 KDO33782.1 - 3.2e-16 58.9 1.3 2.1e-06 27.5 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Bromodomain PF00439.25 KDO33782.1 - 5e-16 58.5 0.0 1.4e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Kelch_6 PF13964.6 KDO33782.1 - 1.7e-11 44.0 0.5 0.04 14.2 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KDO33782.1 - 7.6e-11 41.4 6.0 0.0084 15.7 0.0 6.2 5 2 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KDO33782.1 - 2.2e-09 37.2 2.6 0.0045 17.0 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KDO33782.1 - 6.1e-05 22.8 3.0 2.5 8.2 0.0 5.4 4 2 0 4 4 4 2 Kelch motif EB PF01683.18 KDO33782.1 - 5.8 7.3 6.6 1.4 9.3 1.3 2.2 2 0 0 2 2 2 0 EB module Exo_endo_phos PF03372.23 KDO33783.1 - 3.8e-19 69.1 0.1 5.1e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PRD_Mga PF08270.11 KDO33784.1 - 0.032 13.9 0.9 0.093 12.4 0.1 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain DUF948 PF06103.11 KDO33784.1 - 6.6 7.1 10.4 12 6.2 0.3 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) RNA_pol_L_2 PF13656.6 KDO33785.1 - 4.5e-24 84.0 0.0 5.4e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KDO33785.1 - 5.5e-06 25.7 0.0 7.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain KRBA1 PF15287.6 KDO33785.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 KRBA1 family repeat Pex24p PF06398.11 KDO33785.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin p450 PF00067.22 KDO33786.1 - 1.7e-45 155.6 0.0 3.3e-45 154.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KDO33787.1 - 3.5e-12 45.8 0.0 3.8e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIG2_2 PF13772.6 KDO33788.1 - 3.8e-06 27.2 0.0 6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KDO33788.1 - 0.00085 19.9 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GGACT PF06094.12 KDO33789.1 - 9.5e-07 29.4 0.0 1.7e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KDO33789.1 - 7.1e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Kinesin PF00225.23 KDO33790.1 - 9.5e-82 274.6 0.0 1.4e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO33790.1 - 2.6e-12 46.9 0.2 1.5e-10 41.2 0.2 2.7 1 1 0 1 1 1 1 Microtubule binding THOC7 PF05615.13 KDO33790.1 - 0.016 15.5 1.4 0.031 14.5 1.4 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 Spc7 PF08317.11 KDO33790.1 - 0.016 14.1 5.6 0.025 13.5 5.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BBP1_C PF15272.6 KDO33790.1 - 0.028 14.2 2.1 0.049 13.4 2.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ADIP PF11559.8 KDO33790.1 - 0.11 12.6 6.6 0.75 9.9 6.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KDO33790.1 - 0.13 11.6 7.2 0.28 10.4 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TRAF_BIRC3_bd PF16673.5 KDO33790.1 - 0.17 11.7 2.1 0.41 10.5 2.1 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain TBCC_N PF16752.5 KDO33790.1 - 0.24 11.8 3.0 0.55 10.7 3.0 1.5 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain SOGA PF11365.8 KDO33790.1 - 1.2 10.3 7.0 13 7.0 3.7 2.5 1 1 1 2 2 2 0 Protein SOGA DUF724 PF05266.14 KDO33790.1 - 2 8.2 5.1 3.6 7.4 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.14 KDO33790.1 - 2.6 8.4 8.9 4.5 7.6 8.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PhyH PF05721.13 KDO33791.1 - 1.5e-49 169.2 0.0 1.8e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KDO33791.1 - 0.015 15.7 0.2 0.4 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase p450 PF00067.22 KDO33792.1 - 1.5e-79 267.9 0.0 1.9e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-HC5HC2H_2 PF13832.6 KDO33793.1 - 1.3e-38 131.5 67.2 8.5e-16 58.1 12.1 7.5 6 1 1 7 7 7 5 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO33793.1 - 4e-25 87.9 76.6 1.3e-13 51.0 7.6 8.5 6 2 2 8 8 8 3 PHD-like zinc-binding domain PHD PF00628.29 KDO33793.1 - 8.6e-18 64.0 82.4 1.3e-07 31.4 4.1 7.9 8 0 0 8 8 8 6 PHD-finger PHD_2 PF13831.6 KDO33793.1 - 3.1e-13 49.0 23.8 1.2e-12 47.1 1.3 6.7 7 0 0 7 7 7 3 PHD-finger C1_1 PF00130.22 KDO33793.1 - 0.00031 20.6 5.4 0.0012 18.7 0.7 8.0 7 1 1 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) NADH-G_4Fe-4S_3 PF10588.9 KDO33793.1 - 0.03 13.9 3.9 0.88 9.2 0.6 3.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region AT_hook PF02178.19 KDO33793.1 - 0.26 11.3 13.0 5.3 7.2 0.3 3.3 2 0 0 2 2 2 0 AT hook motif Cullin_binding PF03556.15 KDO33794.1 - 3.6e-33 114.5 1.0 6.1e-33 113.8 1.0 1.4 1 0 0 1 1 1 1 Cullin binding SAP PF02037.27 KDO33794.1 - 2.1e-09 36.9 1.5 4.6e-09 35.8 1.5 1.7 1 0 0 1 1 1 1 SAP domain VMR2 PF17055.5 KDO33794.1 - 0.0086 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Viral matrix protein M2 HgmA PF04209.13 KDO33796.1 - 4.1e-209 694.6 2.1 4.6e-209 694.4 2.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase RGS PF00615.19 KDO33797.1 - 0.0076 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2304 PF10066.9 KDO33797.1 - 0.025 14.8 2.6 0.025 14.8 2.6 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Xpo1 PF08389.12 KDO33798.1 - 3.9e-26 91.9 0.0 3e-25 89.0 0.0 2.6 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 KDO33798.1 - 0.091 13.2 0.4 50 4.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeats Dynein_C PF18199.1 KDO33800.1 - 1.9e-74 250.6 0.0 3.4e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KDO33800.1 - 2e-73 246.2 0.0 3.6e-73 245.3 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 KDO33800.1 - 7.7e-46 156.7 10.7 6.9e-45 153.6 4.2 2.7 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KDO33800.1 - 5e-42 143.5 0.0 9e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KDO33800.1 - 4.2e-34 117.2 0.1 4.7e-33 113.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Laminin_II PF06009.12 KDO33800.1 - 0.0079 16.2 3.2 0.018 15.1 0.8 2.4 2 0 0 2 2 2 1 Laminin Domain II CLZ PF16526.5 KDO33800.1 - 0.14 12.6 2.9 0.12 12.7 0.2 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_6 PF12774.7 KDO33801.1 - 1.4e-136 454.8 0.0 1.5e-135 451.4 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KDO33801.1 - 1.8e-87 294.1 0.0 3.4e-87 293.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KDO33801.1 - 4.6e-79 265.4 0.0 8.7e-79 264.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KDO33801.1 - 6.2e-59 198.6 0.0 8.1e-53 178.6 0.0 3.8 3 0 0 3 3 3 3 P-loop containing dynein motor region Kelch_5 PF13854.6 KDO33801.1 - 1e-30 105.2 4.2 1.1e-06 28.5 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KDO33801.1 - 1.9e-27 94.6 5.5 1.8e-08 34.4 0.0 6.3 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KDO33801.1 - 1.9e-26 91.8 13.6 5.9e-06 26.2 0.0 6.7 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO33801.1 - 1e-23 82.6 6.0 3.1e-08 33.1 0.1 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KDO33801.1 - 5.3e-23 80.1 14.0 3.6e-06 26.7 0.3 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KDO33801.1 - 9.3e-23 80.0 12.1 8.9e-07 29.1 0.0 7.5 7 0 0 7 7 7 3 Galactose oxidase, central domain AAA_5 PF07728.14 KDO33801.1 - 5.1e-20 71.9 0.0 1.2e-09 38.3 0.0 5.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KDO33801.1 - 2e-15 57.0 0.0 6.6e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KDO33801.1 - 6.6e-14 51.9 0.4 1.9e-12 47.2 0.4 3.2 2 1 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KDO33801.1 - 2.4e-06 28.1 2.5 0.47 10.8 0.0 5.0 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KDO33801.1 - 2.5e-06 27.8 0.4 1.1 9.5 0.0 4.6 4 0 0 4 4 4 1 AAA domain TIG PF01833.24 KDO33801.1 - 4.9e-06 26.5 0.6 1.1e-05 25.4 0.6 1.7 1 0 0 1 1 1 1 IPT/TIG domain AAA_30 PF13604.6 KDO33801.1 - 2.1e-05 24.4 1.8 2.1 8.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KDO33801.1 - 9.3e-05 22.8 6.1 0.49 10.7 0.1 4.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KDO33801.1 - 0.00024 21.6 0.8 1.8 9.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain Filamin PF00630.19 KDO33801.1 - 0.00033 21.4 0.0 0.00072 20.3 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat ATP_bind_1 PF03029.17 KDO33801.1 - 0.0022 17.8 0.3 0.03 14.1 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 KDO33801.1 - 0.0028 18.1 0.1 1.9 8.9 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KDO33801.1 - 0.003 17.1 0.6 1.8 8.0 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.17 KDO33801.1 - 0.013 15.2 0.5 7.5 6.2 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 KDO33801.1 - 0.024 14.8 1.0 17 5.6 0.0 3.9 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KDO33801.1 - 0.062 12.7 5.4 2.8 7.3 0.1 4.1 4 1 0 4 4 4 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KDO33801.1 - 0.12 12.8 1.4 12 6.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 KDO33801.1 - 0.2 11.4 1.5 28 4.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain 2-Hacid_dh_C PF02826.19 KDO33802.1 - 3.6e-56 189.3 0.0 1.3e-55 187.5 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO33802.1 - 1.7e-26 92.5 0.1 1.9e-26 92.3 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KDO33802.1 - 7e-06 26.3 0.4 0.00012 22.2 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KDO33802.1 - 0.00018 21.1 0.1 0.0026 17.4 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KDO33802.1 - 0.0015 19.1 1.1 0.13 12.9 0.1 2.8 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KDO33802.1 - 0.0086 16.0 0.6 0.019 14.8 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KDO33802.1 - 0.01 15.9 0.5 0.027 14.5 0.5 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CoA_binding_2 PF13380.6 KDO33802.1 - 0.017 15.6 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Shikimate_DH PF01488.20 KDO33802.1 - 0.077 13.1 0.1 0.44 10.6 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 KDO33802.1 - 0.18 11.6 0.5 0.8 9.6 0.0 2.2 3 0 0 3 3 3 0 Rossmann-like domain 2-Hacid_dh_C PF02826.19 KDO33803.1 - 8.2e-54 181.7 0.0 1.5e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO33803.1 - 3.8e-22 78.4 0.0 5.9e-22 77.8 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KDO33803.1 - 0.00036 20.7 0.4 0.0015 18.7 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding_2 PF13380.6 KDO33803.1 - 0.0016 18.9 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain IlvN PF07991.12 KDO33803.1 - 0.008 15.8 0.0 0.047 13.3 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KDO33803.1 - 0.015 15.4 0.8 0.024 14.7 0.1 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KDO33803.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KDO33803.1 - 0.11 12.5 0.0 0.57 10.2 0.0 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh PF00389.30 KDO33804.1 - 6.3e-08 32.4 0.0 7.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 KDO33805.1 - 2.5e-54 183.3 0.0 3.5e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO33805.1 - 7.7e-28 96.8 0.0 9.2e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KDO33805.1 - 3.4e-06 27.3 0.1 6.3e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KDO33805.1 - 0.0018 17.9 0.0 0.0051 16.4 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KDO33805.1 - 0.0039 17.1 0.1 0.0066 16.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KDO33805.1 - 0.033 14.2 0.3 0.072 13.2 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CoA_binding_2 PF13380.6 KDO33805.1 - 0.098 13.2 0.0 0.32 11.5 0.0 1.8 1 1 0 1 1 1 0 CoA binding domain EF-hand_7 PF13499.6 KDO33806.1 - 0.0065 16.9 0.0 0.022 15.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO33806.1 - 0.0065 15.9 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 EF hand V_ATPase_I PF01496.19 KDO33806.1 - 0.13 10.1 4.7 0.18 9.7 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3552 PF12072.8 KDO33806.1 - 6.8 6.0 24.0 12 5.3 11.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TPR_19 PF14559.6 KDO33808.1 - 1.5e-05 25.4 18.9 0.00095 19.6 0.4 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33808.1 - 0.0037 17.3 4.7 14 6.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33808.1 - 0.057 14.1 0.0 0.057 14.1 0.0 6.5 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33808.1 - 0.058 13.8 0.1 65 4.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33808.1 - 0.27 11.6 0.6 25 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33808.1 - 1.7 9.4 5.4 75 4.3 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KDO33808.1 - 4.1 7.9 5.1 14 6.2 0.0 4.1 6 0 0 6 6 6 0 PPR repeat Thaumatin PF00314.17 KDO33809.1 - 9.7e-05 22.1 3.1 0.00082 19.1 2.0 2.7 2 1 1 3 3 3 2 Thaumatin family SOG2 PF10428.9 KDO33809.1 - 1.1 8.4 9.8 1.4 8.0 9.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AFG1_ATPase PF03969.16 KDO33810.1 - 1.2e-89 300.7 0.5 9.2e-87 291.3 0.1 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KDO33810.1 - 2.7e-05 24.6 0.4 0.00017 22.0 0.1 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO33810.1 - 0.00048 20.4 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KDO33810.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KDO33810.1 - 0.018 15.5 0.0 0.065 13.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KDO33810.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KDO33810.1 - 0.042 14.4 0.0 0.19 12.2 0.0 1.9 1 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 KDO33810.1 - 0.051 13.6 0.1 0.22 11.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KDO33810.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KDO33810.1 - 0.083 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KDO33810.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain N1221 PF07923.13 KDO33811.1 - 0.0039 16.4 0.6 0.0051 16.0 0.6 1.2 1 0 0 1 1 1 1 N1221-like protein Snapin_Pallidin PF14712.6 KDO33811.1 - 0.0081 16.6 3.5 0.025 15.0 2.6 2.3 1 1 1 2 2 2 1 Snapin/Pallidin BLOC1_2 PF10046.9 KDO33811.1 - 0.0085 16.4 2.7 0.022 15.1 2.7 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med28 PF11594.8 KDO33811.1 - 0.022 14.8 1.3 0.059 13.4 0.7 1.9 1 1 1 2 2 2 0 Mediator complex subunit 28 TBCC_N PF16752.5 KDO33811.1 - 0.035 14.5 1.1 0.074 13.5 1.1 1.6 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain LMBR1 PF04791.16 KDO33811.1 - 0.039 12.9 2.0 0.052 12.5 2.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein A_thal_3526 PF09713.10 KDO33811.1 - 0.041 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Dor1 PF04124.12 KDO33811.1 - 0.053 12.2 3.3 0.12 11.0 2.2 1.9 1 1 1 2 2 2 0 Dor1-like family Sec34 PF04136.15 KDO33811.1 - 0.066 13.1 4.4 0.64 9.9 0.5 2.6 1 1 2 3 3 3 0 Sec34-like family FlxA PF14282.6 KDO33811.1 - 0.07 13.1 1.4 0.2 11.6 1.4 1.7 1 0 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.22 KDO33811.1 - 0.16 12.2 5.6 0.58 10.4 5.6 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KDO33811.1 - 0.23 12.0 2.1 0.92 10.0 0.2 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 KDO33811.1 - 0.23 11.9 7.2 0.034 14.5 2.5 2.1 3 0 0 3 3 1 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 KDO33811.1 - 0.26 11.5 7.3 0.21 11.8 4.5 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2937 PF11157.8 KDO33811.1 - 0.3 10.8 0.9 0.92 9.2 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) OmpH PF03938.14 KDO33811.1 - 0.4 11.0 5.2 0.87 9.9 5.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AATF-Che1 PF13339.6 KDO33811.1 - 0.52 11.0 8.1 1.9 9.2 8.1 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor TPR_MLP1_2 PF07926.12 KDO33811.1 - 0.59 10.2 7.8 0.12 12.4 4.4 1.7 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF4446 PF14584.6 KDO33811.1 - 0.6 10.1 4.3 1.1 9.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Spc7 PF08317.11 KDO33811.1 - 0.6 8.9 7.5 0.81 8.5 7.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMCO5 PF14992.6 KDO33811.1 - 0.67 9.5 7.5 0.96 9.0 7.5 1.3 1 0 0 1 1 1 0 TMCO5 family TMPIT PF07851.13 KDO33811.1 - 0.7 9.1 2.1 0.92 8.7 2.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 KDO33811.1 - 0.79 9.5 4.9 0.2 11.5 2.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KDO33811.1 - 0.89 10.2 5.1 1.8 9.2 1.5 2.7 1 1 1 2 2 2 0 SlyX Jnk-SapK_ap_N PF09744.9 KDO33811.1 - 0.94 9.7 8.8 0.31 11.3 5.0 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 KDO33811.1 - 1.6 9.2 5.0 12 6.4 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 HalX PF08663.10 KDO33811.1 - 3.2 8.1 6.5 14 6.1 0.3 3.1 3 1 0 3 3 2 0 HalX domain KELK PF15796.5 KDO33811.1 - 3.9 8.0 10.4 0.47 10.9 5.7 2.0 2 0 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 KDO33812.1 - 0.77 10.3 18.2 1.5 9.3 8.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Guanylate_cyc PF00211.20 KDO33813.1 - 2.8e-13 49.9 0.0 9.7e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Ribosom_S12_S23 PF00164.25 KDO33814.1 - 1.9e-50 169.3 0.6 2.4e-50 168.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Pkinase PF00069.25 KDO33815.1 - 2.4e-72 243.5 0.0 2.9e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33815.1 - 6.8e-40 137.0 0.0 9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO33815.1 - 1.7e-09 37.4 0.0 5e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO33815.1 - 2e-06 26.9 0.0 2.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO33815.1 - 0.00023 21.2 0.2 0.00071 19.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KDO33815.1 - 0.0041 16.5 0.1 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KDO33815.1 - 0.0047 16.6 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KDO33815.1 - 0.009 15.0 0.0 0.019 13.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KDO33815.1 - 0.014 15.0 0.1 0.03 13.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase_C PF00433.24 KDO33815.1 - 0.03 15.0 0.2 0.076 13.7 0.2 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF5448 PF17526.2 KDO33815.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Mitofilin PF09731.9 KDO33816.1 - 1.7e-41 142.8 60.7 9.8e-40 137.0 60.7 2.5 1 1 0 1 1 1 1 Mitochondrial inner membrane protein SPT_ssu-like PF11779.8 KDO33817.1 - 4.2e-09 35.9 1.9 4.6e-09 35.8 1.9 1.0 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ras PF00071.22 KDO33818.1 - 4.7e-37 127.1 0.6 8.9e-36 122.9 0.6 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KDO33818.1 - 2.9e-26 92.0 0.2 2.9e-26 92.0 0.2 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO33818.1 - 1.9e-09 37.2 0.1 3.3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO33818.1 - 4.2e-05 23.6 0.1 8.9e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO33818.1 - 0.0015 18.0 0.0 0.002 17.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KDO33818.1 - 0.002 17.9 0.6 0.0049 16.6 0.2 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SAM35 PF10806.8 KDO33818.1 - 0.0097 16.2 0.5 0.015 15.5 0.5 1.2 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex YjeF_N PF03853.15 KDO33818.1 - 0.064 13.1 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus FeoB_N PF02421.18 KDO33818.1 - 0.096 12.2 0.3 0.46 10.0 0.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Ank_2 PF12796.7 KDO33819.1 - 9.1e-39 131.9 9.2 1.4e-11 44.8 0.0 5.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33819.1 - 3.1e-33 113.7 10.4 8.3e-09 35.8 0.1 9.4 2 2 9 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33819.1 - 6e-30 99.9 14.5 0.0093 16.4 0.1 10.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KDO33819.1 - 6.2e-30 102.9 11.3 9.9e-08 32.1 0.0 7.1 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO33819.1 - 3.4e-26 90.5 19.8 0.0022 18.3 0.1 10.5 10 0 0 10 10 10 7 Ankyrin repeat RNase_T PF00929.24 KDO33820.1 - 2.4e-06 28.2 0.1 2e-05 25.2 0.1 2.3 1 1 0 1 1 1 1 Exonuclease SH3_9 PF14604.6 KDO33821.1 - 2e-30 104.4 3.7 7e-15 54.6 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KDO33821.1 - 5e-26 90.0 0.1 1.2e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KDO33821.1 - 4.1e-21 74.4 0.0 4.7e-11 42.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Pkinase PF00069.25 KDO33822.1 - 1.8e-71 240.6 0.0 2.5e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33822.1 - 4e-38 131.2 0.0 7.4e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KDO33822.1 - 9.9e-19 65.4 6.2 2.2e-05 23.7 0.3 5.0 5 0 0 5 5 4 4 EF hand EF-hand_6 PF13405.6 KDO33822.1 - 3.8e-17 60.7 0.8 0.00042 20.0 0.0 5.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KDO33822.1 - 4.2e-16 59.2 0.3 1.1e-05 25.8 0.1 4.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KDO33822.1 - 1.7e-14 53.4 4.7 0.00034 20.4 0.1 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO33822.1 - 9.1e-08 31.3 0.5 0.038 13.5 0.1 4.5 5 0 0 5 5 5 2 EF hand Kinase-like PF14531.6 KDO33822.1 - 8.4e-05 22.0 0.4 0.00036 19.9 0.4 1.9 1 1 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.7 KDO33822.1 - 0.0001 22.2 0.0 0.051 13.5 0.0 3.0 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 KDO33822.1 - 0.0019 17.6 0.2 0.0035 16.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 KDO33822.1 - 0.0045 17.3 0.4 0.087 13.2 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain Haspin_kinase PF12330.8 KDO33822.1 - 0.0072 15.3 0.3 0.18 10.7 0.3 2.2 1 1 0 1 1 1 1 Haspin like kinase domain RelB_N PF18506.1 KDO33822.1 - 0.028 14.2 0.3 37 4.2 0.1 3.6 3 0 0 3 3 3 0 RelB Antitoxin alpha helical domain APH PF01636.23 KDO33822.1 - 0.053 13.4 0.1 1 9.3 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 KDO33822.1 - 0.14 12.5 0.2 15 5.9 0.0 2.8 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PglD_N PF17836.1 KDO33822.1 - 0.17 12.6 0.0 4.8 7.9 0.0 2.5 2 0 0 2 2 2 0 PglD N-terminal domain C2 PF00168.30 KDO33823.1 - 5.2e-13 49.2 0.0 7.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain Cu-oxidase PF00394.22 KDO33824.1 - 2.6e-32 112.1 0.0 1.3e-30 106.7 0.0 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KDO33824.1 - 7.7e-30 103.4 10.7 3.3e-27 94.9 1.4 4.2 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KDO33824.1 - 2.2e-25 89.0 2.9 3.4e-24 85.2 0.1 3.1 2 1 2 4 4 4 1 Multicopper oxidase CENP-F_leu_zip PF10473.9 KDO33826.1 - 2.4e-06 27.6 83.7 0.00029 20.9 8.5 10.7 2 2 4 9 9 9 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KDO33826.1 - 0.00079 20.0 49.8 0.0058 17.2 0.5 10.0 3 3 8 11 11 11 2 Initiation control protein YabA ATG16 PF08614.11 KDO33826.1 - 0.0013 19.0 10.3 0.0013 19.0 10.3 8.4 1 1 5 8 8 8 5 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KDO33826.1 - 0.0057 15.6 97.5 0.022 13.6 1.2 7.6 2 2 6 9 9 9 4 Spc7 kinetochore protein THOC7 PF05615.13 KDO33826.1 - 0.018 15.4 0.7 0.018 15.4 0.7 9.4 5 3 3 8 8 8 0 Tho complex subunit 7 Rhabdo_ncap_2 PF03216.13 KDO33826.1 - 0.4 10.1 8.5 0.22 10.9 1.1 2.9 3 0 0 3 3 3 0 Rhabdovirus nucleoprotein FlaC_arch PF05377.11 KDO33826.1 - 1.7 9.1 17.7 45 4.5 0.0 8.3 10 0 0 10 10 10 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KDO33826.1 - 2 7.9 86.2 0.22 11.1 25.5 7.8 2 2 3 6 6 6 0 Intermediate filament protein APG6_N PF17675.1 KDO33826.1 - 2.3 8.7 113.5 0.3 11.6 8.0 10.3 1 1 6 9 9 9 0 Apg6 coiled-coil region Fez1 PF06818.15 KDO33826.1 - 2.7 8.4 88.2 1.4 9.3 8.0 7.0 1 1 6 7 7 7 0 Fez1 KASH_CCD PF14662.6 KDO33826.1 - 2.8 7.7 78.2 3.8 7.3 11.6 7.1 4 2 1 6 6 6 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KDO33826.1 - 3.2 7.0 81.9 0.37 10.1 14.7 7.2 2 2 2 6 6 6 0 Growth-arrest specific micro-tubule binding Thymopoietin PF08198.11 KDO33827.1 - 0.11 12.1 0.1 20 4.9 0.0 3.3 2 0 0 2 2 2 0 Thymopoietin protein RRM_occluded PF16842.5 KDO33827.1 - 0.6 10.0 6.7 23 4.9 0.1 4.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif CENP-F_leu_zip PF10473.9 KDO33827.1 - 3.2 7.8 66.5 1.5 8.9 1.8 7.6 3 2 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Surfac_D-trimer PF09006.11 KDO33827.1 - 8.2 6.4 9.1 2.5 8.1 0.1 3.7 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation FAST_1 PF06743.15 KDO33829.1 - 5.7e-07 29.4 0.0 0.0086 16.0 0.0 4.8 4 2 2 6 6 6 2 FAST kinase-like protein, subdomain 1 DUF4716 PF15837.5 KDO33829.1 - 0.1 12.7 1.0 0.62 10.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) FAM221 PF14753.6 KDO33831.1 - 3.4e-32 111.6 18.6 5.2e-32 111.0 18.6 1.2 1 0 0 1 1 1 1 Protein FAM221A/B Arm PF00514.23 KDO33835.1 - 1.9e-10 40.4 10.7 0.0023 17.9 0.0 6.6 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KDO33835.1 - 4.4e-07 29.6 1.0 1.3 9.5 0.0 5.4 5 1 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KDO33835.1 - 5.7e-05 23.4 9.1 0.09 13.2 0.1 4.3 3 2 0 3 3 3 2 HEAT repeats Atx10homo_assoc PF09759.9 KDO33835.1 - 0.0048 16.9 0.1 0.52 10.4 0.0 3.4 1 1 3 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KDO33835.1 - 0.0054 16.2 0.1 0.39 10.1 0.0 2.6 1 1 0 2 2 2 1 Armadillo-like IBN_N PF03810.19 KDO33835.1 - 0.0077 16.1 0.7 10 6.1 0.0 3.7 4 1 1 5 5 5 1 Importin-beta N-terminal domain UNC45-central PF11701.8 KDO33835.1 - 0.015 15.3 0.3 0.13 12.2 0.1 2.4 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Cnd1 PF12717.7 KDO33835.1 - 0.12 12.4 0.4 33 4.5 0.0 3.3 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO33835.1 - 0.33 11.5 14.2 7.3 7.2 0.1 5.6 4 4 1 5 5 5 0 HEAT-like repeat zf-RING_2 PF13639.6 KDO33837.1 - 2.2e-13 50.3 12.9 2.2e-13 50.3 12.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KDO33837.1 - 4.6e-08 32.6 12.8 1.6e-07 30.9 12.8 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO33837.1 - 4.9e-07 29.9 12.9 1.5e-06 28.4 12.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO33837.1 - 8.9e-06 25.4 12.0 8.9e-06 25.4 12.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO33837.1 - 9.7e-06 25.4 15.2 1.3e-05 25.0 9.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO33837.1 - 9.4e-05 22.4 12.4 0.00016 21.6 7.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO33837.1 - 0.0001 22.1 13.3 0.0001 22.1 13.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO33837.1 - 0.00062 19.7 12.0 0.00062 19.7 12.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO33837.1 - 0.012 15.5 10.5 0.029 14.2 10.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO33837.1 - 0.034 14.2 7.4 0.034 14.2 7.4 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2781 PF10914.8 KDO33837.1 - 0.15 12.4 7.4 0.034 14.6 2.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2781) zf-RING_10 PF16685.5 KDO33837.1 - 0.16 12.1 10.5 0.65 10.2 7.4 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KDO33837.1 - 0.23 11.7 12.5 0.51 10.6 11.1 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KDO33837.1 - 1.7 8.3 10.6 4.8 6.9 10.6 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KDO33837.1 - 7 6.5 13.0 1.4 8.8 7.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_assoc PF16606.5 KDO33838.1 - 0.016 15.4 0.2 0.043 14.0 0.2 1.7 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers Afi1 PF07792.12 KDO33838.1 - 1.1 9.7 6.3 0.32 11.5 0.7 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1697 PF08002.11 KDO33839.1 - 3.8e-27 95.4 0.0 5.6e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) UMPH-1 PF05822.12 KDO33840.1 - 1.2e-81 273.9 0.0 1.4e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KDO33840.1 - 0.0001 22.8 0.2 0.00019 21.9 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aminotran_5 PF00266.19 KDO33841.1 - 5.3e-20 71.7 0.0 9e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KDO33841.1 - 8.5e-08 31.1 0.0 1.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KDO33841.1 - 3.8e-06 26.3 0.0 8.4e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KDO33841.1 - 0.0051 16.1 0.2 0.82 8.9 0.0 2.3 1 1 0 2 2 2 2 Beta-eliminating lyase SepSecS PF05889.13 KDO33841.1 - 0.12 11.0 0.0 0.24 10.1 0.0 1.5 1 1 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 KDO33841.1 - 0.25 10.6 1.9 0.44 9.8 1.9 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DnaJ PF00226.31 KDO33842.1 - 2.6e-22 78.7 0.7 3.9e-22 78.1 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 KDO33842.1 - 3e-17 63.2 16.3 1.9e-09 37.6 1.0 3.2 2 1 1 3 3 3 3 Transmembrane Fragile-X-F protein CD225 PF04505.12 KDO33842.1 - 0.026 14.6 0.4 0.026 14.6 0.4 4.0 4 1 0 4 4 4 0 Interferon-induced transmembrane protein Sugar_tr PF00083.24 KDO33843.1 - 2.8e-52 178.1 22.1 3.7e-52 177.7 22.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO33843.1 - 4.8e-31 108.0 48.6 1.6e-28 99.7 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KDO33843.1 - 3.6e-05 23.2 9.0 3.6e-05 23.2 9.0 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB fn3 PF00041.21 KDO33844.1 - 4e-39 132.8 4.2 8.6e-11 42.0 0.0 6.3 6 0 0 6 6 6 5 Fibronectin type III domain Kelch_5 PF13854.6 KDO33844.1 - 3.9e-20 71.4 2.4 1.2e-06 28.4 0.0 6.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KDO33844.1 - 1.4e-06 28.4 6.9 0.0056 16.9 0.2 6.3 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.25 KDO33844.1 - 0.00027 20.4 6.8 0.034 13.8 0.2 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KDO33844.1 - 0.0023 17.9 3.4 11 6.2 0.0 4.8 4 0 0 4 4 4 1 Kelch motif P_proprotein PF01483.20 KDO33844.1 - 0.0052 16.8 0.1 0.064 13.3 0.1 2.4 1 1 0 1 1 1 1 Proprotein convertase P-domain Pur_ac_phosph_N PF16656.5 KDO33844.1 - 0.14 12.8 2.8 3.4 8.3 0.1 4.2 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Gly_rich PF12810.7 KDO33844.1 - 2.6 7.9 89.0 3 7.7 82.1 2.7 2 1 0 2 2 2 0 Glycine rich protein SPDY PF03771.16 KDO33844.1 - 4 7.4 7.4 4.2 7.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF317) UPF0489 PF12640.7 KDO33845.1 - 1e-43 149.6 0.0 1.8e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain Arginase PF00491.21 KDO33845.1 - 0.24 10.9 0.6 0.32 10.4 0.6 1.2 1 0 0 1 1 1 0 Arginase family PPR_long PF17177.4 KDO33846.1 - 7.2e-10 38.6 0.3 0.0002 20.8 0.0 2.6 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KDO33846.1 - 1.9e-06 27.9 0.1 0.0062 16.7 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 KDO33846.1 - 2.2e-05 24.4 0.3 0.67 10.3 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 KDO33846.1 - 0.025 14.6 0.0 12 6.0 0.0 3.9 3 1 1 4 4 4 0 Pentatricopeptide repeat domain DUF1221 PF06760.11 KDO33846.1 - 0.063 12.8 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) AAA PF00004.29 KDO33847.1 - 3.3e-07 30.8 0.0 7.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO33847.1 - 3.9e-07 30.6 0.1 2.9e-06 27.8 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 KDO33847.1 - 4.4e-05 23.3 0.0 8.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KDO33847.1 - 0.00011 22.2 0.1 0.24 11.3 0.0 2.8 3 0 0 3 3 3 2 NTPase NACHT PF05729.12 KDO33847.1 - 0.00013 22.0 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KDO33847.1 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KDO33847.1 - 0.00023 21.2 0.0 0.00093 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KDO33847.1 - 0.00031 21.0 0.0 0.00069 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KDO33847.1 - 0.00055 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO33847.1 - 0.0007 19.8 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO33847.1 - 0.00082 19.1 0.1 0.0022 17.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO33847.1 - 0.0019 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO33847.1 - 0.0027 18.1 0.0 0.011 16.0 0.0 2.0 1 1 1 2 2 1 1 AAA domain AAA_22 PF13401.6 KDO33847.1 - 0.0042 17.4 0.1 0.017 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KDO33847.1 - 0.0062 16.1 0.2 0.19 11.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KDO33847.1 - 0.0068 16.9 0.0 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KDO33847.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.12 KDO33847.1 - 0.015 15.0 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KDO33847.1 - 0.016 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KDO33847.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KDO33847.1 - 0.018 15.5 0.0 0.053 13.9 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KDO33847.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KDO33847.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 KDO33847.1 - 0.02 14.0 0.1 0.04 13.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KDO33847.1 - 0.023 14.5 0.1 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KDO33847.1 - 0.024 14.0 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KDO33847.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KDO33847.1 - 0.047 13.3 0.2 0.097 12.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KDO33847.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KDO33847.1 - 0.084 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KDO33847.1 - 0.087 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KDO33847.1 - 0.15 11.6 0.0 0.44 10.1 0.0 1.8 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain EcKinase PF02958.20 KDO33848.1 - 8.9e-13 48.2 0.1 2.1e-11 43.7 0.0 2.6 3 0 0 3 3 3 1 Ecdysteroid kinase APH PF01636.23 KDO33848.1 - 1e-11 45.3 1.6 1.6e-11 44.6 1.6 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KDO33848.1 - 6.8e-10 38.4 0.0 4.1e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 KDO33848.1 - 0.00032 20.4 0.0 0.00099 18.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KDO33848.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HHH PF00633.23 KDO33848.1 - 0.18 11.7 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Tyrosinase PF00264.20 KDO33849.1 - 1.9e-10 41.4 0.0 2.1e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase TPR_12 PF13424.6 KDO33850.1 - 1.9e-13 50.5 5.8 5.6e-08 33.0 0.9 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33850.1 - 2.9e-11 42.7 1.5 0.00063 19.5 0.0 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO33850.1 - 1.2e-09 37.6 4.6 0.00018 21.3 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33850.1 - 1.3e-08 34.4 2.0 0.65 10.4 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO33850.1 - 2.6e-05 24.0 5.3 1 9.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33850.1 - 0.003 17.2 4.7 5.3 6.8 0.1 4.3 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 KDO33850.1 - 0.022 15.1 0.1 13 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 KDO33850.1 - 0.04 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 KDO33850.1 - 4 8.5 7.9 15 6.7 1.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33850.1 - 6.2 7.4 8.4 16 6.1 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF63 PF01889.17 KDO33851.1 - 0.12 12.6 7.7 0.22 11.7 7.7 1.5 1 1 0 1 1 1 0 Membrane protein of unknown function DUF63 Syja_N PF02383.18 KDO33852.1 - 7.1e-80 268.7 0.0 9.9e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain TAFII55_N PF04658.13 KDO33853.1 - 2.1e-22 79.6 2.9 1.2e-21 77.1 0.1 2.7 2 2 0 2 2 2 1 TAFII55 protein conserved region NuA4 PF09340.10 KDO33853.1 - 0.56 10.1 4.0 18 5.3 0.1 2.7 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 NAC PF01849.18 KDO33854.1 - 0.27 11.3 1.6 0.32 11.0 0.3 1.7 2 0 0 2 2 2 0 NAC domain LPMO_10 PF03067.15 KDO33855.1 - 6.6e-24 85.6 0.3 1.2e-23 84.8 0.3 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_1 PF00734.18 KDO33855.1 - 1.7e-12 47.1 9.1 5.3e-12 45.5 9.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain PT PF04886.12 KDO33855.1 - 1.1 8.9 43.3 1.6 8.4 12.2 3.5 1 1 1 2 2 2 0 PT repeat IATP PF04568.12 KDO33856.1 - 0.0002 21.7 2.9 0.00031 21.1 2.9 1.4 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HBS1_N PF08938.10 KDO33856.1 - 0.059 13.7 1.0 0.13 12.5 0.6 1.7 1 1 1 2 2 2 0 HBS1 N-terminus Peptidase_C1 PF00112.23 KDO33857.1 - 3.4e-54 184.2 1.2 3.4e-54 184.2 1.2 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Ricin_B_lectin PF00652.22 KDO33857.1 - 1.8e-29 102.5 12.9 2.5e-15 56.9 2.8 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO33857.1 - 3.4e-10 40.5 13.7 7.3e-05 23.4 4.3 4.3 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO33857.1 - 0.0013 18.4 2.1 1.1 8.8 0.0 3.0 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain Inhibitor_I29 PF08246.12 KDO33857.1 - 0.0029 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Ricin_B_lectin PF00652.22 KDO33858.1 - 2.1e-31 108.8 16.1 9.6e-14 51.7 4.2 2.6 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO33858.1 - 1.3e-10 41.9 8.7 9.7e-06 26.2 2.5 3.8 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO33858.1 - 9.1e-05 22.1 0.7 0.32 10.6 0.5 2.4 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain SAE2 PF08573.10 KDO33859.1 - 0.042 15.0 3.5 0.054 14.6 3.5 1.1 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3597 PF12200.8 KDO33859.1 - 0.081 13.5 4.9 0.11 13.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) RabGAP-TBC PF00566.18 KDO33860.1 - 2.2e-32 112.5 0.0 3.3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YqjK PF13997.6 KDO33860.1 - 0.12 12.6 0.8 20 5.5 0.2 2.5 2 0 0 2 2 2 0 YqjK-like protein PH PF00169.29 KDO33861.1 - 7.3e-16 58.6 0.1 1.3e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO33861.1 - 4.9e-06 26.9 0.1 0.0078 16.6 0.0 2.5 2 1 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 KDO33861.1 - 0.0018 18.5 0.0 0.0055 16.9 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KDO33861.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 KDO33861.1 - 0.033 14.3 0.0 0.057 13.5 0.0 1.6 1 1 0 1 1 1 0 PH domain FHA PF00498.26 KDO33862.1 - 1e-12 48.2 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO33862.1 - 1e-08 35.3 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Cep57_CLD PF14073.6 KDO33863.1 - 6e-06 26.4 26.4 6e-06 26.4 26.4 2.8 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 KDO33863.1 - 0.0046 17.4 0.1 0.0046 17.4 0.1 4.8 4 1 2 6 6 6 2 Centrosome microtubule-binding domain of Cep57 DUF4140 PF13600.6 KDO33863.1 - 0.014 15.8 1.7 0.014 15.8 1.7 6.4 4 3 1 5 5 4 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KDO33863.1 - 0.27 11.3 21.3 3.1 7.8 2.6 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KDO33863.1 - 0.4 10.8 0.1 0.4 10.8 0.1 5.1 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.11 KDO33863.1 - 0.44 9.4 44.5 0.016 14.1 18.8 4.1 3 1 1 4 4 4 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KDO33863.1 - 0.81 9.9 39.3 0.099 12.9 0.5 5.7 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KDO33863.1 - 0.85 10.1 40.2 0.55 10.8 15.3 4.6 2 2 2 4 4 4 0 Apg6 coiled-coil region FNIP_M PF14637.6 KDO33863.1 - 4.3 7.3 12.7 20 5.1 0.2 4.4 3 1 2 5 5 5 0 Folliculin-interacting protein middle domain Prefoldin PF02996.17 KDO33863.1 - 4.7 7.1 24.8 0.8 9.6 1.1 6.1 3 3 2 6 6 6 0 Prefoldin subunit FH2 PF02181.23 KDO33863.1 - 7 5.7 20.7 4.4 6.3 6.5 3.7 2 1 1 3 3 3 0 Formin Homology 2 Domain WW PF00397.26 KDO33865.1 - 3.3e-11 43.0 4.2 3.2e-06 27.1 2.3 2.7 2 1 0 2 2 2 2 WW domain PQQ PF01011.21 KDO33865.1 - 0.038 13.9 0.2 7 6.8 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Ank_4 PF13637.6 KDO33866.1 - 1.6e-19 70.0 1.1 1.5e-10 41.4 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO33866.1 - 2e-17 63.6 0.4 1.6e-14 54.2 0.1 3.9 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO33866.1 - 1.1e-16 60.7 1.4 5.2e-07 29.8 0.8 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO33866.1 - 1.5e-16 60.0 5.9 0.00056 20.2 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KDO33866.1 - 3.7e-16 57.6 3.0 0.00074 19.8 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat DUF2993 PF11209.8 KDO33867.1 - 0.023 15.0 0.9 0.079 13.2 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) DUF1664 PF07889.12 KDO33867.1 - 0.92 9.6 17.6 0.029 14.4 3.4 4.4 3 1 1 5 5 5 0 Protein of unknown function (DUF1664) FlxA PF14282.6 KDO33867.1 - 3.6 7.6 11.9 4.6 7.3 0.1 3.7 3 0 0 3 3 3 0 FlxA-like protein BLOC1_2 PF10046.9 KDO33867.1 - 5.5 7.4 9.0 8.6 6.7 0.8 3.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 KDO33867.1 - 5.9 4.7 11.0 10 3.9 11.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nuc_sug_transp PF04142.15 KDO33868.1 - 1.9e-28 99.6 11.6 2.5e-28 99.2 11.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KDO33868.1 - 4.5e-06 26.1 3.9 4.5e-06 26.1 3.9 1.8 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport DUF2515 PF10720.9 KDO33868.1 - 0.017 14.3 0.0 0.044 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) CRT-like PF08627.10 KDO33868.1 - 0.018 14.0 2.3 0.041 12.8 0.8 2.0 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO33868.1 - 0.1 12.7 26.0 0.19 11.9 8.6 2.1 2 0 0 2 2 2 0 EamA-like transporter family Fer2 PF00111.27 KDO33869.1 - 1.4e-09 37.8 0.6 2e-09 37.3 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ras PF00071.22 KDO33870.1 - 5e-42 143.3 0.0 7.7e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO33870.1 - 2.9e-15 56.5 0.0 6.3e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase KHA PF11834.8 KDO33870.1 - 1.2e-12 47.7 0.0 3.1e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 KHA, dimerisation domain of potassium ion channel Arf PF00025.21 KDO33870.1 - 1.7e-06 27.6 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RAP PF08373.10 KDO33870.1 - 2.1e-06 27.7 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RAP domain GTP_EFTU PF00009.27 KDO33870.1 - 5.8e-06 26.0 0.2 1.9e-05 24.3 0.0 1.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FAST_1 PF06743.15 KDO33870.1 - 8.9e-06 25.6 0.0 0.003 17.5 0.0 3.6 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 MMR_HSR1 PF01926.23 KDO33870.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DCX PF03607.17 KDO33870.1 - 0.099 12.8 0.1 1 9.5 0.0 2.8 3 0 0 3 3 3 0 Doublecortin FAST_2 PF08368.12 KDO33870.1 - 0.12 13.2 0.0 0.34 11.7 0.0 1.7 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Kinesin PF00225.23 KDO33871.1 - 1.2e-87 294.0 0.0 3.2e-87 292.6 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO33871.1 - 1.6e-18 67.1 0.0 2.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Ecm29 PF13001.7 KDO33872.1 - 6.3e-43 147.2 0.7 1.1e-42 146.4 0.7 1.4 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.22 KDO33872.1 - 0.0011 19.0 1.4 25 5.5 0.0 6.2 5 0 0 5 5 5 1 HEAT repeat Rota_NS6 PF04866.12 KDO33872.1 - 0.044 14.0 0.0 0.22 11.8 0.0 2.2 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 Lyase_1 PF00206.20 KDO33875.1 - 7.8e-107 357.3 0.0 1e-106 356.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KDO33875.1 - 2.6e-25 88.6 0.6 8.8e-25 86.9 0.2 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus Gly-zipper_YMGG PF13441.6 KDO33876.1 - 0.0035 17.1 4.7 0.0056 16.4 4.7 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KDO33876.1 - 0.0097 15.9 5.0 0.016 15.2 5.0 1.3 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 KDO33876.1 - 0.013 15.3 3.4 0.02 14.7 3.4 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 KDO33876.1 - 0.059 13.2 3.2 0.096 12.5 3.2 1.3 1 0 0 1 1 1 0 Glycine-zipper domain SAM_1 PF00536.30 KDO33877.1 - 7.6e-14 51.9 0.1 2.1e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 KDO33877.1 - 1.1e-12 47.9 1.0 9.3e-09 35.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO33877.1 - 8.7e-09 35.8 0.0 0.00051 20.5 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 KDO33877.1 - 1.1e-08 35.1 0.1 3.1e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IQ PF00612.27 KDO33877.1 - 4.5e-08 32.2 26.5 0.01 15.6 0.1 6.3 6 0 0 6 6 6 4 IQ calmodulin-binding motif Ank_2 PF12796.7 KDO33877.1 - 6.9e-08 33.0 0.1 3.9e-07 30.6 0.1 2.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO33877.1 - 9.4e-07 29.0 0.9 0.064 13.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat MT PF12777.7 KDO33877.1 - 9.9e-07 28.1 0.2 9.9e-07 28.1 0.2 3.4 4 0 0 4 4 3 2 Microtubule-binding stalk of dynein motor Ank_3 PF13606.6 KDO33877.1 - 2e-05 24.6 0.0 0.54 11.0 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat SAM_3 PF18016.1 KDO33877.1 - 0.019 14.8 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nsp1_C PF05064.13 KDO33877.1 - 1.9 8.3 11.0 0.092 12.6 2.3 2.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region PX PF00787.24 KDO33878.1 - 2.7e-16 59.6 0.1 3e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 PX domain Ank_2 PF12796.7 KDO33879.1 - 4.3e-27 94.5 27.3 5e-08 33.4 0.1 4.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33879.1 - 7.2e-21 74.3 22.6 6e-07 29.9 0.3 8.3 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33879.1 - 8.2e-16 57.9 12.2 0.022 15.1 0.1 8.7 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33879.1 - 1.9e-15 55.4 9.0 1.8 9.4 0.0 10.4 9 2 2 11 11 11 3 Ankyrin repeat DUF5049 PF16468.5 KDO33879.1 - 0.00019 21.3 0.1 24 4.9 0.0 5.1 3 1 2 5 5 5 1 Domain of unknown function (DUF5049) DUF3322 PF11795.8 KDO33879.1 - 0.088 12.8 0.0 1.5 8.8 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank PF00023.30 KDO33879.1 - 0.12 12.9 17.1 23 5.7 0.1 7.1 5 1 3 8 8 8 0 Ankyrin repeat Bromodomain PF00439.25 KDO33880.1 - 6.4e-34 115.9 0.0 8.4e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 Bromodomain WSD PF15613.6 KDO33880.1 - 4.1e-11 43.2 0.7 4.1e-11 43.2 0.7 3.2 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DNMT1-RFD PF12047.8 KDO33880.1 - 3.1e-05 24.1 0.0 0.0053 16.8 0.0 2.6 2 0 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain RWP-RK PF02042.15 KDO33882.1 - 4.3e-19 68.2 0.1 9.8e-19 67.1 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 KDO33882.1 - 5.5e-13 48.9 0.1 1.7e-12 47.3 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO33882.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 1.9 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KDO33882.1 - 0.0042 17.3 0.1 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF3813 PF12758.7 KDO33882.1 - 0.012 15.9 0.2 0.28 11.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) CDC45 PF02724.14 KDO33882.1 - 0.11 10.8 5.0 0.15 10.3 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 KDO33883.1 - 5.7e-18 64.9 15.1 6.5e-07 30.0 2.7 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO33883.1 - 3.3e-08 33.7 0.1 0.0016 18.7 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 KDO33883.1 - 0.0047 15.3 2.1 0.0057 15.0 2.1 1.1 1 0 0 1 1 1 1 CDC45-like protein CNDH2_C PF16858.5 KDO33883.1 - 0.024 14.5 1.5 0.04 13.8 1.5 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Apt1 PF10351.9 KDO33883.1 - 0.39 9.5 2.1 0.56 9.0 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pes-10 PF07149.11 KDO33883.1 - 0.46 9.5 8.2 0.69 8.9 8.2 1.2 1 0 0 1 1 1 0 Pes-10 RXT2_N PF08595.11 KDO33883.1 - 2 8.4 5.9 3.7 7.5 5.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 KDO33883.1 - 2.9 7.2 12.0 4.4 6.6 12.0 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 KDO33883.1 - 5.3 6.1 20.7 8.9 5.3 20.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KDO33883.1 - 6.2 6.5 7.0 12 5.5 7.0 1.4 1 0 0 1 1 1 0 FAM176 family PI3K_1B_p101 PF10486.9 KDO33883.1 - 7 4.3 5.5 10 3.8 5.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 KDO33883.1 - 8.6 5.6 15.8 14 4.9 15.8 1.2 1 0 0 1 1 1 0 NOA36 protein tRNA-synt_2 PF00152.20 KDO33884.1 - 3.1e-83 279.5 0.0 4.1e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KDO33884.1 - 4.8e-13 48.9 0.0 8.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KDO33884.1 - 2.1e-09 37.2 0.1 0.00012 21.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Cys_rich_FGFR PF00839.17 KDO33884.1 - 0.097 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Cysteine rich repeat Sacchrp_dh_NADP PF03435.18 KDO33885.1 - 5.4e-17 62.3 0.0 8.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF2781 PF10914.8 KDO33886.1 - 2.1e-20 73.6 11.3 2.9e-20 73.2 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Glycos_transf_1 PF00534.20 KDO33887.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 RRM_1 PF00076.22 KDO33888.1 - 2.5e-20 72.0 0.0 1.8e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 KDO33888.1 - 0.00025 20.4 0.4 0.00069 19.0 0.4 1.8 1 0 0 1 1 1 1 Lsm interaction motif RRM_occluded PF16842.5 KDO33888.1 - 0.0026 17.6 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RL PF17797.1 KDO33888.1 - 0.034 14.1 0.1 1.3 9.0 0.0 2.8 2 1 0 2 2 2 0 RL domain NLRC4_HD2 PF17776.1 KDO33888.1 - 0.098 13.2 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 NLRC4 helical domain HD2 WD40 PF00400.32 KDO33889.1 - 8.7e-44 146.7 22.5 6.6e-08 33.1 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO33889.1 - 1e-12 48.2 1.6 0.073 13.4 0.0 6.8 2 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO33889.1 - 3.5e-05 23.3 0.0 0.00011 21.6 0.0 1.9 1 1 1 2 2 2 1 WD40-like domain Nup160 PF11715.8 KDO33889.1 - 7.4e-05 21.6 1.3 0.36 9.4 0.1 4.0 2 1 0 4 4 4 2 Nucleoporin Nup120/160 PQQ PF01011.21 KDO33889.1 - 0.016 15.1 0.5 9.9 6.3 0.1 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat Frtz PF11768.8 KDO33889.1 - 0.021 13.1 0.0 3.1 6.0 0.0 2.6 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KDO33889.1 - 0.027 13.4 2.3 11 4.8 0.0 3.4 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain LisH PF08513.11 KDO33889.1 - 0.03 14.3 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 LisH Ge1_WD40 PF16529.5 KDO33889.1 - 0.032 13.2 0.2 1.5 7.7 0.1 3.3 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KDO33889.1 - 0.051 14.1 3.4 26 5.5 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain LisH_TPL PF17814.1 KDO33889.1 - 0.067 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 LisH-like dimerisation domain Peptidase_M24 PF00557.24 KDO33890.1 - 6.3e-59 199.2 1.6 6.3e-59 199.2 0.2 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 KDO33890.1 - 1.2e-25 89.7 0.0 3.7e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain CC2-LZ PF16516.5 KDO33890.1 - 0.073 13.5 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MTP18 PF10558.9 KDO33891.1 - 1.8e-22 80.1 2.0 6.6e-12 45.7 0.4 2.0 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Sulfate_transp PF00916.20 KDO33892.1 - 1.3e-22 80.1 21.7 2.4e-22 79.2 21.7 1.5 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KDO33892.1 - 2.5e-14 53.1 0.0 6.2e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KDO33892.1 - 9.2e-08 31.7 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain F420_oxidored PF03807.17 KDO33892.1 - 0.034 14.7 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Metallophos PF00149.28 KDO33893.1 - 4.1e-13 50.3 0.0 6.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KDO33893.1 - 1e-06 29.2 0.2 2.6e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KDO33893.1 - 0.00031 21.6 1.5 0.00078 20.2 0.1 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C RHD3 PF05879.12 KDO33894.1 - 0.00082 17.6 0.1 0.0042 15.3 0.0 2.0 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KDO33894.1 - 0.0016 18.5 0.0 0.0054 16.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 KDO33894.1 - 0.003 16.9 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KDO33894.1 - 0.0072 16.4 0.1 0.17 12.0 0.1 2.4 1 1 1 2 2 2 1 Dynamin family FliG_M PF14841.6 KDO33894.1 - 0.034 14.4 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 0 FliG middle domain TPR_2 PF07719.17 KDO33895.1 - 1e-29 100.2 8.9 0.0039 17.2 0.0 11.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO33895.1 - 3.1e-23 80.6 1.2 0.0079 16.0 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO33895.1 - 2.5e-22 79.1 2.9 3.2e-07 30.8 0.1 5.9 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 KDO33895.1 - 7.6e-22 77.7 20.6 2.1e-06 28.3 0.0 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KDO33895.1 - 3.9e-21 73.5 1.4 0.022 14.9 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KDO33895.1 - 6.6e-20 70.1 21.3 0.0014 19.3 0.0 11.1 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 KDO33895.1 - 3.4e-19 68.9 19.8 0.00068 19.9 0.1 7.9 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KDO33895.1 - 3.4e-19 68.2 0.0 4.5e-06 26.2 0.0 8.0 7 1 2 9 9 9 4 TPR repeat TPR_9 PF13371.6 KDO33895.1 - 2.9e-15 56.2 6.6 2.9e-05 24.1 0.0 5.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO33895.1 - 1.3e-11 44.0 0.2 0.19 12.2 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO33895.1 - 1.4e-10 41.2 3.6 0.056 13.7 0.0 4.9 2 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KDO33895.1 - 1.1e-08 34.5 5.3 0.32 11.1 0.0 8.7 8 0 0 8 8 8 1 Tetratricopeptide repeat NARP1 PF12569.8 KDO33895.1 - 3.9e-05 22.8 1.3 0.00097 18.2 0.1 3.0 3 1 0 4 4 4 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KDO33895.1 - 9.4e-05 22.2 16.5 0.61 10.0 0.0 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KDO33895.1 - 0.00024 20.4 0.1 3 7.0 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO33895.1 - 0.00027 21.3 16.2 2 9.3 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 KDO33895.1 - 0.0026 18.1 3.0 0.4 11.1 0.1 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO33895.1 - 0.0072 16.9 7.4 1e+02 3.9 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KDO33895.1 - 0.034 13.9 1.2 12 5.6 0.0 3.9 4 0 0 4 4 3 0 26S proteasome subunit RPN7 MAS20 PF02064.15 KDO33895.1 - 0.051 13.7 0.1 85 3.2 0.0 4.4 3 1 3 6 6 6 0 MAS20 protein import receptor DUF5113 PF17140.4 KDO33895.1 - 0.055 13.3 1.8 2 8.2 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF5113) TPR_3 PF07720.12 KDO33895.1 - 0.075 13.1 0.4 20 5.3 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1635 PF07795.11 KDO33895.1 - 0.13 12.1 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TPR_21 PF09976.9 KDO33895.1 - 0.21 11.3 0.0 0.21 11.3 0.0 3.1 5 0 0 5 5 4 0 Tetratricopeptide repeat-like domain BTAD PF03704.17 KDO33895.1 - 2.6 8.5 11.2 19 5.6 0.3 4.6 3 2 2 5 5 4 0 Bacterial transcriptional activator domain Ion_trans PF00520.31 KDO33896.1 - 2.4e-22 79.4 16.3 3.3e-22 78.9 16.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KDO33896.1 - 2.6e-13 49.7 3.3 2.6e-13 49.7 3.3 2.3 2 1 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KDO33896.1 - 0.0053 16.8 0.0 0.022 14.8 0.0 2.1 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain GAS PF13851.6 KDO33897.1 - 0.0013 18.1 20.4 0.0013 18.1 20.4 6.6 1 1 4 6 6 6 3 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 KDO33897.1 - 0.019 14.9 1.1 0.019 14.9 1.1 11.8 8 6 3 11 11 11 0 Prefoldin subunit zf-CHY PF05495.12 KDO33898.1 - 2.1e-18 66.6 21.4 2.1e-18 66.6 21.4 3.3 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.6 KDO33898.1 - 4.2e-05 23.8 13.4 4.2e-05 23.8 13.4 5.7 2 2 2 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KDO33898.1 - 0.00048 19.8 4.2 0.00048 19.8 4.2 4.7 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KDO33898.1 - 0.0033 17.4 7.9 0.0033 17.4 7.9 4.2 6 0 0 6 6 6 1 RING-type zinc-finger YL1 PF05764.13 KDO33898.1 - 0.19 11.8 7.9 0.27 11.3 7.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein ubiquitin PF00240.23 KDO33899.1 - 0.0029 17.3 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO33899.1 - 0.0035 17.2 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BHD_3 PF10405.9 KDO33900.1 - 5.4e-24 84.4 0.1 1.1e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KDO33900.1 - 2.1e-14 53.1 0.1 6.6e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KDO33900.1 - 2.6e-08 34.3 0.5 2e-07 31.5 0.2 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily BHD_2 PF10404.9 KDO33900.1 - 1.3e-07 32.4 3.4 1.3e-07 32.4 3.4 2.6 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 KDO33900.1 - 0.002 17.8 0.0 0.0058 16.3 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain FXR_C3 PF16097.5 KDO33901.1 - 0.69 10.6 6.6 0.47 11.2 3.7 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Na_sulph_symp PF00939.19 KDO33902.1 - 2e-29 103.0 42.2 2.7e-29 102.5 42.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KDO33902.1 - 1.5e-27 97.6 5.5 4.9e-13 49.7 2.9 2.8 1 1 0 2 2 2 2 SPX domain CitMHS PF03600.16 KDO33902.1 - 2.8e-27 95.7 40.7 2.8e-27 95.7 40.7 2.1 1 1 1 2 2 2 2 Citrate transporter FbpA PF05833.11 KDO33902.1 - 0.037 12.8 0.4 0.054 12.2 0.4 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IF-2B PF01008.17 KDO33903.1 - 1.1e-68 231.6 1.7 2.4e-68 230.4 1.7 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Csa1 PF06023.12 KDO33903.1 - 0.033 13.5 0.2 0.047 13.1 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 UQ_con PF00179.26 KDO33904.1 - 4.4e-41 139.8 0.0 5.6e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KDO33904.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KDO33904.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain PfkB PF00294.24 KDO33905.1 - 4.7e-46 157.5 1.2 7.5e-46 156.8 1.2 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KDO33905.1 - 1.8e-05 24.3 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PhyH PF05721.13 KDO33905.1 - 0.00096 19.5 0.0 0.0064 16.8 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Carb_kinase PF01256.17 KDO33905.1 - 0.0015 18.1 0.1 0.0029 17.1 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate kinase tRNA-synt_1 PF00133.22 KDO33906.1 - 1.6e-217 723.6 0.0 2.2e-217 723.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KDO33906.1 - 6e-25 88.0 0.1 1.2e-24 87.1 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KDO33906.1 - 4e-13 48.9 0.4 0.001 17.9 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KDO33906.1 - 1.9e-05 24.2 0.0 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain CDC50 PF03381.15 KDO33907.1 - 1.6e-53 182.0 0.0 2e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF202 PF02656.15 KDO33907.1 - 0.96 9.9 4.2 0.77 10.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 KDO33907.1 - 1.1 9.4 4.8 0.55 10.3 0.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 KDO33907.1 - 1.3 8.9 7.3 2.9 7.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PTPA PF03095.15 KDO33908.1 - 1.7e-117 392.2 0.0 2e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_S18 PF01084.20 KDO33909.1 - 3.1e-16 59.3 0.3 6.2e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Peptidase_M50 PF02163.22 KDO33915.1 - 3.8e-07 29.6 4.0 1.3e-06 27.9 4.3 1.6 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 KDO33915.1 - 0.0083 15.8 1.7 0.0083 15.8 1.7 2.2 1 1 1 2 2 2 2 Peptidase M50B-like MoaC PF01967.21 KDO33916.1 - 3.8e-52 176.0 1.2 4.5e-52 175.7 1.2 1.1 1 0 0 1 1 1 1 MoaC family ATP_bind_1 PF03029.17 KDO33917.1 - 3.2e-71 239.9 0.4 5.4e-71 239.2 0.4 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KDO33917.1 - 2e-08 34.0 0.1 5.6e-08 32.6 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KDO33917.1 - 2e-07 30.8 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KDO33917.1 - 1.1e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO33917.1 - 2.2e-05 24.9 0.0 3.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KDO33917.1 - 0.00022 21.0 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KDO33917.1 - 0.00031 20.3 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 KDO33917.1 - 0.00049 19.8 0.0 0.0065 16.1 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KDO33917.1 - 0.00083 19.4 0.0 0.0093 16.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KDO33917.1 - 0.00089 19.8 0.1 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO33917.1 - 0.0015 18.7 0.1 0.0036 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO33917.1 - 0.0025 18.1 0.0 0.0063 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain PhoH PF02562.16 KDO33917.1 - 0.0026 17.3 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein RsgA_GTPase PF03193.16 KDO33917.1 - 0.0044 16.9 0.0 2.2 8.2 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase NB-ARC PF00931.22 KDO33917.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.15 KDO33917.1 - 0.0064 16.4 0.0 0.044 13.7 0.0 2.1 1 1 0 1 1 1 1 NTPase AAA_30 PF13604.6 KDO33917.1 - 0.0066 16.2 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KDO33917.1 - 0.011 15.5 0.1 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KDO33917.1 - 0.017 14.7 0.6 0.13 11.8 0.6 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KDO33917.1 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.18 KDO33917.1 - 0.019 14.3 0.1 0.14 11.5 0.0 2.3 3 0 0 3 3 3 0 Septin AAA_31 PF13614.6 KDO33917.1 - 0.02 14.8 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KDO33917.1 - 0.021 14.1 1.1 0.024 13.9 0.0 1.8 3 0 0 3 3 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KDO33917.1 - 0.022 13.8 0.1 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 KDO33917.1 - 0.023 14.1 0.2 0.076 12.4 0.1 1.9 2 1 1 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.17 KDO33917.1 - 0.023 14.8 0.9 0.56 10.2 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 KDO33917.1 - 0.024 15.0 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KDO33917.1 - 0.025 14.5 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 KDO33917.1 - 0.026 13.7 0.2 0.63 9.1 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KDO33917.1 - 0.026 13.9 0.9 0.21 11.0 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein Roc PF08477.13 KDO33917.1 - 0.028 14.6 0.4 0.095 12.9 0.0 2.1 3 0 0 3 3 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO33917.1 - 0.03 13.8 0.0 0.21 11.0 0.0 2.3 2 1 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 KDO33917.1 - 0.03 13.9 0.1 2.1 7.9 0.0 2.8 1 1 0 2 2 2 0 Ras family UvrD-helicase PF00580.21 KDO33917.1 - 0.039 13.5 0.4 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain SRPRB PF09439.10 KDO33917.1 - 0.041 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MipZ PF09140.11 KDO33917.1 - 0.044 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 KDO33917.1 - 0.062 13.1 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 KDO33917.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KDO33917.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KDO33917.1 - 0.092 13.1 0.0 0.33 11.4 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 KDO33917.1 - 0.1 12.8 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KDO33917.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 KDO33917.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KDO33917.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Stanniocalcin PF03298.13 KDO33917.1 - 0.21 10.9 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Stanniocalcin family RecQ_Zn_bind PF16124.5 KDO33919.1 - 1.6e-18 67.2 8.1 1.6e-18 67.2 8.1 2.2 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 KDO33919.1 - 1.8e-16 60.4 0.0 4.2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO33919.1 - 4.9e-16 59.0 0.0 2.4e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 KDO33919.1 - 1.3e-13 50.8 0.0 2.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain RQC PF09382.10 KDO33919.1 - 2.3e-11 43.5 0.2 6.4e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 RQC domain PagP PF07017.11 KDO33919.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP GSHPx PF00255.19 KDO33920.1 - 1e-25 89.4 0.0 2e-21 75.6 0.1 2.1 1 1 1 2 2 2 2 Glutathione peroxidase GSHPx PF00255.19 KDO33921.1 - 1.7e-28 98.4 0.1 3.4e-28 97.4 0.1 1.5 1 1 0 1 1 1 1 Glutathione peroxidase PINIT PF14324.6 KDO33921.1 - 0.09 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 PINIT domain GSHPx PF00255.19 KDO33923.1 - 1.8e-26 91.8 0.1 3.5e-25 87.7 0.1 2.3 1 1 0 1 1 1 1 Glutathione peroxidase DUF2244 PF10003.9 KDO33923.1 - 0.009 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) RabGAP-TBC PF00566.18 KDO33924.1 - 2.7e-33 115.4 0.2 7.8e-33 113.9 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 KDO33924.1 - 1.7e-06 28.2 0.4 0.00013 22.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33924.1 - 6.7e-06 26.1 0.7 0.0029 18.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KDO33924.1 - 1.3e-05 25.4 0.0 0.017 15.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KDO33924.1 - 4e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33924.1 - 0.0002 21.9 0.1 0.01 16.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Metallophos PF00149.28 KDO33925.1 - 2.4e-21 77.2 0.2 4.3e-21 76.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO33925.1 - 1.3e-14 54.8 0.0 5.8e-14 52.7 0.0 2.2 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KDO33925.1 - 3.7e-11 43.5 3.5 2.2e-09 37.7 0.1 2.7 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Pkinase PF00069.25 KDO33926.1 - 4.1e-75 252.5 0.0 4.8e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33926.1 - 8.2e-33 113.8 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO33926.1 - 1.6e-05 24.4 0.1 0.00068 19.0 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KDO33926.1 - 0.00031 19.8 0.1 0.0084 15.1 0.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO33926.1 - 0.00059 19.3 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO33926.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KDO33926.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 KDO33926.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CBS PF00571.28 KDO33927.1 - 5e-21 74.9 2.6 0.00029 21.2 0.0 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 KDO33927.1 - 7.5e-09 35.4 0.0 1.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF2431 PF10354.9 KDO33928.1 - 5.8e-47 160.1 0.0 1e-46 159.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Actin PF00022.19 KDO33929.1 - 7.1e-93 311.4 0.0 1.3e-92 310.6 0.0 1.4 1 1 0 1 1 1 1 Actin LRR_8 PF13855.6 KDO33930.1 - 4.9e-14 51.8 7.3 1.2e-06 28.1 0.4 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KDO33930.1 - 1.3e-09 38.2 0.1 2.3e-05 24.7 0.1 4.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO33930.1 - 1.4e-05 25.4 9.6 3.9e-05 24.0 9.6 1.8 1 0 0 1 1 1 1 LNR domain DUF4571 PF15137.6 KDO33930.1 - 0.016 14.9 0.4 0.036 13.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4571) Cys_Met_Meta_PP PF01053.20 KDO33931.1 - 6e-141 469.4 0.0 6.9e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KDO33931.1 - 1.1e-11 44.6 0.1 1.6e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KDO33931.1 - 5.3e-10 39.2 0.3 7.9e-10 38.6 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KDO33931.1 - 2.7e-06 26.6 0.5 4.3e-06 25.9 0.5 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KDO33931.1 - 1.5e-05 24.4 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KDO33931.1 - 0.0014 17.6 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 KDO33931.1 - 0.0038 15.8 0.1 0.0055 15.3 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KDO33931.1 - 0.046 12.4 0.0 0.065 11.9 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 KDO33931.1 - 0.054 13.7 0.0 0.57 10.4 0.0 2.4 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain MFS_2 PF13347.6 KDO33932.1 - 8.7e-06 24.5 13.3 0.0018 16.9 2.1 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_Mycoplasma PF07672.13 KDO33932.1 - 0.43 9.8 5.5 0.17 11.1 1.6 2.3 3 0 0 3 3 3 0 Mycoplasma MFS transporter DUF423 PF04241.15 KDO33932.1 - 2.1 8.6 11.0 0.25 11.6 1.3 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF423) Citrate_bind PF16114.5 KDO33934.1 - 2.6e-89 297.4 0.0 4.8e-89 296.5 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KDO33934.1 - 7.8e-24 84.4 0.0 1.3e-21 77.1 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KDO33934.1 - 3.5e-14 52.9 0.0 6.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KDO33934.1 - 3.7e-08 34.0 0.0 1.3e-07 32.2 0.0 2.1 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KDO33934.1 - 0.0009 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain IBR PF01485.21 KDO33935.1 - 0.00076 19.6 8.4 0.00076 19.6 8.4 3.1 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Nre_C PF04895.12 KDO33935.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal Nre, C-terminal zf-Di19 PF05605.12 KDO33935.1 - 0.32 11.3 15.3 5.5 7.4 5.2 3.8 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SAM_2 PF07647.17 KDO33936.1 - 3.2e-09 36.8 0.0 7.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO33936.1 - 1.1e-08 35.3 0.4 2.3e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF3394 PF11874.8 KDO33936.1 - 0.022 14.5 0.1 0.076 12.7 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) HhH-GPD PF00730.25 KDO33936.1 - 0.039 14.4 0.0 0.098 13.1 0.0 1.7 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein AphA_like PF14557.6 KDO33936.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Caps_synth_GfcC PF06251.11 KDO33936.1 - 0.25 10.9 1.0 0.51 9.9 0.2 1.7 2 0 0 2 2 2 0 Capsule biosynthesis GfcC KOW PF00467.29 KDO33937.1 - 0.099 12.6 0.7 43 4.3 0.1 3.8 3 0 0 3 3 3 0 KOW motif NUDIX PF00293.28 KDO33938.1 - 2.1e-16 60.1 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 KDO33938.1 - 1.7e-08 34.6 2.5 1.7e-08 34.6 2.5 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KDO33938.1 - 0.0076 16.6 1.5 0.51 10.9 0.2 3.0 2 0 0 2 2 2 1 Zinc-finger double domain Glyco_trans_4_4 PF13579.6 KDO33938.1 - 0.024 15.1 0.7 0.32 11.4 0.7 2.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain GAGA PF09237.11 KDO33938.1 - 0.12 12.2 0.4 14 5.6 0.0 2.4 2 0 0 2 2 2 0 GAGA factor DUF4451 PF14616.6 KDO33938.1 - 0.17 12.1 1.9 1.1 9.5 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) YacG PF03884.14 KDO33938.1 - 0.64 9.8 3.1 2.2 8.1 0.9 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-C2H2_4 PF13894.6 KDO33938.1 - 2.1 9.4 9.1 6.5 7.9 1.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger EF-hand_1 PF00036.32 KDO33939.1 - 4.7e-17 60.2 16.9 0.00087 18.7 3.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KDO33939.1 - 4.9e-15 54.1 15.8 0.00057 19.6 2.7 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KDO33939.1 - 3.1e-12 46.7 13.5 1.4e-06 28.7 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KDO33939.1 - 1e-11 44.5 10.2 0.0006 19.6 0.6 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KDO33939.1 - 0.0083 15.6 19.4 1.8 8.2 1.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 KDO33939.1 - 0.04 13.9 2.1 1.7 8.6 0.1 2.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-MYND PF01753.18 KDO33940.1 - 7.1e-11 42.0 15.7 1.5e-10 41.0 15.7 1.6 1 0 0 1 1 1 1 MYND finger EF-hand_like PF09279.11 KDO33940.1 - 0.028 14.9 0.3 0.081 13.4 0.2 1.8 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Caleosin PF05042.13 KDO33940.1 - 0.17 11.8 0.4 13 5.7 0.1 2.5 1 1 2 3 3 3 0 Caleosin related protein zf-HIT PF04438.16 KDO33940.1 - 3.1 7.8 13.1 1.3 9.0 10.5 1.7 2 0 0 2 2 2 0 HIT zinc finger Pro_isomerase PF00160.21 KDO33941.1 - 3.1e-48 164.0 0.0 7e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KDO33941.1 - 5.2e-11 42.4 0.2 1.1e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KDO33941.1 - 1.5e-06 28.3 0.1 5.3e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KDO33941.1 - 0.0054 16.5 0.3 0.029 14.2 0.4 2.2 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KDO33941.1 - 0.08 13.1 0.0 0.37 11.0 0.0 2.1 1 1 1 2 2 2 0 U-box domain TAA-Trp-ring PF15401.6 KDO33941.1 - 0.27 11.7 1.7 2.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin IBR PF01485.21 KDO33942.1 - 0.0094 16.2 13.4 0.0094 16.2 13.4 3.5 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Nre_C PF04895.12 KDO33942.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal Nre, C-terminal SAM_2 PF07647.17 KDO33943.1 - 2.3e-09 37.2 0.1 8.1e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO33943.1 - 1.1e-08 35.4 0.4 2.5e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF3394 PF11874.8 KDO33943.1 - 0.034 13.8 0.1 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) HhH-GPD PF00730.25 KDO33943.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Tropomyosin_1 PF12718.7 KDO33944.1 - 0.0068 16.6 12.3 0.0068 16.6 12.3 2.7 1 1 1 2 2 2 1 Tropomyosin like zf-NADH-PPase PF09297.11 KDO33944.1 - 0.044 13.4 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Chorein_N PF12624.7 KDO33944.1 - 0.064 13.4 2.2 0.13 12.4 1.0 2.2 2 1 0 2 2 2 0 N-terminal region of Chorein or VPS13 DUF1949 PF09186.11 KDO33944.1 - 0.59 10.1 4.7 0.26 11.2 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) LIF_OSM PF01291.17 KDO33944.1 - 0.71 10.0 5.1 6.2 6.9 0.5 2.4 2 1 0 2 2 2 0 LIF / OSM family DUF4253 PF14062.6 KDO33944.1 - 0.97 9.6 5.4 0.64 10.2 2.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4253) zf-ZPR1 PF03367.13 KDO33944.1 - 2.2 8.1 5.8 0.38 10.6 0.3 2.3 1 1 0 2 2 2 0 ZPR1 zinc-finger domain TFIIA PF03153.13 KDO33944.1 - 7.7 6.4 21.0 11 5.9 21.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.27 KDO33945.1 - 2e-38 131.9 0.0 5.1e-26 91.4 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KDO33945.1 - 1e-14 54.3 0.0 2.8e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KDO33945.1 - 5e-12 45.7 0.0 1.3e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KDO33945.1 - 0.00011 22.6 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KDO33945.1 - 0.00098 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV VHL_C PF17211.3 KDO33946.1 - 0.084 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 VHL box domain Csm1_N PF18504.1 KDO33946.1 - 0.16 12.3 0.2 0.26 11.7 0.2 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain ATG13 PF10033.9 KDO33948.1 - 1.8e-16 60.6 0.1 1.1e-15 58.0 0.1 2.1 1 1 1 2 2 2 1 Autophagy-related protein 13 EamA PF00892.20 KDO33950.1 - 3.5e-19 69.3 32.3 6.8e-14 52.2 16.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUSP PF06337.12 KDO33951.1 - 1.7e-10 41.4 0.0 2.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 KDO33951.1 - 5.8e-06 26.5 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Arm PF00514.23 KDO33952.1 - 0.0001 22.2 36.2 0.5 10.5 0.1 10.7 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KDO33952.1 - 0.0011 19.3 5.4 0.0028 18.0 0.4 4.2 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KDO33952.1 - 0.002 18.6 8.2 1.6 9.3 0.1 5.2 5 0 0 5 5 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KDO33952.1 - 0.064 13.9 0.8 16 6.2 0.1 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO33952.1 - 0.076 13.1 9.7 0.026 14.6 1.4 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 KDO33952.1 - 0.28 10.8 8.5 1.4 8.5 0.1 4.8 4 1 2 6 6 6 0 Nucleolar pre-ribosomal-associated protein 1 DUF383 PF04063.14 KDO33952.1 - 0.46 10.1 14.8 0.07 12.8 2.7 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF383) KAP PF05804.12 KDO33952.1 - 1.6 6.8 9.4 0.63 8.1 2.7 3.1 2 1 0 3 3 3 0 Kinesin-associated protein (KAP) HEAT PF02985.22 KDO33952.1 - 2.1 8.8 19.5 2.8 8.4 0.1 6.5 7 0 0 7 7 7 0 HEAT repeat Abhydrolase_9_N PF15420.6 KDO33952.1 - 4.1 7.3 8.4 0.27 11.2 1.0 2.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Methyltransf_16 PF10294.9 KDO33953.1 - 6.6e-25 87.8 0.0 8.6e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO33953.1 - 2.1e-06 27.4 0.1 3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KDO33953.1 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO33953.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KDO33953.1 - 0.0021 18.7 0.9 0.026 15.2 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO33953.1 - 0.0022 17.8 0.0 0.0091 15.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO33953.1 - 0.052 14.2 0.0 0.17 12.6 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain GidB PF02527.15 KDO33953.1 - 0.17 11.2 0.3 0.97 8.7 0.1 2.3 2 1 0 2 2 2 0 rRNA small subunit methyltransferase G IQ PF00612.27 KDO33954.1 - 4 7.5 14.6 2.7 8.0 4.1 3.2 2 1 0 2 2 2 0 IQ calmodulin-binding motif zf-CCCH_4 PF18044.1 KDO33955.1 - 1.9e-14 53.0 32.7 3.7e-05 23.4 2.4 4.7 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KDO33955.1 - 1.8e-13 50.0 38.3 4.8e-06 26.4 3.7 4.8 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 KDO33955.1 - 2.2e-12 46.5 33.7 2.7e-05 23.9 3.5 4.8 3 2 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO33955.1 - 7.1e-07 29.9 20.1 0.31 11.8 1.5 4.5 3 1 1 4 4 4 4 Torus domain zf-RING_5 PF14634.6 KDO33955.1 - 1.8e-06 27.8 5.9 2e-06 27.7 3.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCCH_3 PF15663.5 KDO33955.1 - 1.1e-05 25.6 8.7 0.00018 21.7 2.1 3.0 3 1 0 3 3 3 2 Zinc-finger containing family zf-C3HC4_2 PF13923.6 KDO33955.1 - 4.5e-05 23.2 7.7 0.00014 21.7 5.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO33955.1 - 0.0001 22.2 0.4 0.0001 22.2 0.4 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO33955.1 - 0.00019 21.2 6.5 0.00061 19.6 4.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 KDO33955.1 - 0.00032 21.1 38.1 0.018 15.5 1.1 5.1 4 1 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-RING_2 PF13639.6 KDO33955.1 - 0.00032 21.0 5.2 0.00032 21.0 5.2 3.7 4 0 0 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 KDO33955.1 - 0.0069 16.1 2.5 0.0069 16.1 2.5 3.4 3 1 0 3 3 3 1 RING-like zinc finger zf-UDP PF14569.6 KDO33955.1 - 0.012 15.7 2.7 0.026 14.6 2.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 KDO33955.1 - 0.13 12.2 9.9 0.03 14.2 4.6 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-primase PF09329.11 KDO33955.1 - 0.54 10.1 5.2 3.4 7.5 0.7 2.8 2 0 0 2 2 2 0 Primase zinc finger Cytochrome_C554 PF13435.6 KDO33955.1 - 0.68 10.9 5.1 0.18 12.8 1.3 2.0 2 0 0 2 2 1 0 Cytochrome c554 and c-prime zf-C3HC4_4 PF15227.6 KDO33955.1 - 0.83 9.9 9.3 0.88 9.8 5.0 3.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SH3_19 PF18597.1 KDO33956.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain Mlo PF03094.15 KDO33957.1 - 6.4e-05 21.5 6.1 0.00064 18.2 1.7 2.5 2 1 0 2 2 2 2 Mlo family SKG6 PF08693.10 KDO33958.1 - 0.0036 16.7 0.0 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain THF_DHG_CYH_C PF02882.19 KDO33959.1 - 1.6e-64 216.0 0.9 1.6e-64 216.0 0.9 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KDO33959.1 - 1.8e-39 134.6 0.2 2.6e-39 134.1 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KDO33959.1 - 0.00048 19.2 0.2 0.00077 18.5 0.2 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Fic_N PF13784.6 KDO33961.1 - 0.0075 16.3 0.3 0.073 13.1 0.1 2.6 1 1 1 2 2 2 1 Fic/DOC family N-terminal CENP-B_dimeris PF09026.10 KDO33961.1 - 0.68 10.4 7.7 1.8 9.0 7.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO33961.1 - 4.8 6.4 5.5 7.3 5.8 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein GP67 PF17634.2 KDO33961.1 - 5.1 7.6 13.5 3.3 8.2 9.2 2.9 3 0 0 3 3 3 0 Gene product 67 Cwf_Cwc_15 PF04889.12 KDO33961.1 - 5.5 6.7 10.6 15 5.2 6.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_17 PF00332.18 KDO33962.1 - 1.4e-05 24.9 0.3 0.11 12.1 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Patatin PF01734.22 KDO33962.1 - 0.053 13.7 1.1 0.095 12.9 1.1 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase Zip PF02535.22 KDO33963.1 - 4.1e-36 124.9 20.5 7.5e-34 117.4 20.5 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter YrhK PF14145.6 KDO33963.1 - 0.02 14.8 1.8 0.1 12.5 1.6 2.3 2 0 0 2 2 2 0 YrhK-like protein FAD_binding_2 PF00890.24 KDO33965.1 - 2.5e-75 254.1 1.9 3.1e-75 253.9 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KDO33965.1 - 3.2e-09 36.5 0.1 0.0012 18.1 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO33965.1 - 3e-06 27.1 0.3 5e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KDO33965.1 - 2.3e-05 23.7 0.5 0.0025 17.0 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Succ_DH_flav_C PF02910.20 KDO33965.1 - 7.8e-05 22.7 0.1 0.00023 21.2 0.1 1.8 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term NAD_binding_8 PF13450.6 KDO33965.1 - 0.0029 17.8 0.3 0.0075 16.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KDO33965.1 - 0.0058 15.9 0.2 0.0099 15.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KDO33965.1 - 0.01 15.1 4.9 0.2 10.9 0.1 2.9 3 1 0 3 3 3 0 Thi4 family AlaDh_PNT_C PF01262.21 KDO33965.1 - 0.038 13.3 0.2 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KDO33965.1 - 0.16 10.9 0.7 0.28 10.2 0.7 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KDO33965.1 - 1.3 8.3 6.9 19 4.5 5.4 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ank_2 PF12796.7 KDO33969.1 - 2.4e-21 76.1 2.4 5e-06 27.0 0.5 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33969.1 - 2e-18 66.5 4.6 0.00049 20.6 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33969.1 - 5.2e-15 55.3 12.7 1.1e-05 25.6 0.2 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO33969.1 - 1.8e-13 50.2 11.4 0.059 13.8 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KDO33969.1 - 5.8e-11 41.6 1.4 2.4 9.0 0.0 6.2 5 0 0 5 5 5 3 Ankyrin repeat DUF1720 PF08226.11 KDO33969.1 - 4.9 7.6 7.3 15 6.1 6.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) zf-B_box PF00643.24 KDO33970.1 - 6.8e-06 26.1 3.8 1e-05 25.6 3.8 1.3 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KDO33970.1 - 0.003 17.8 2.1 0.0056 16.9 2.1 1.4 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 KDO33970.1 - 0.0062 16.4 6.5 0.0062 16.4 6.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KDO33971.1 - 1.4e-13 50.8 7.2 1.4e-13 50.8 7.2 2.8 2 2 1 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KDO33971.1 - 4.8e-13 49.2 5.9 4.8e-13 49.2 5.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KDO33971.1 - 1.3e-09 37.7 5.3 1.3e-09 37.7 5.3 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO33971.1 - 6.1e-09 35.5 2.5 1.7e-08 34.0 2.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KDO33971.1 - 4.4e-08 33.3 7.6 4.4e-08 33.3 7.6 3.4 2 2 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO33971.1 - 1.6e-07 31.0 3.9 1.6e-07 31.0 3.9 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO33971.1 - 5.3e-07 29.5 2.6 5.3e-07 29.5 2.6 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KDO33971.1 - 3.6e-06 26.9 2.5 3.6e-06 26.9 2.5 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KDO33971.1 - 1.7e-05 24.6 4.1 1.7e-05 24.6 4.1 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KDO33971.1 - 4.2e-05 23.5 1.7 4.2e-05 23.5 1.7 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KDO33971.1 - 8.5e-05 22.3 5.0 8.5e-05 22.3 5.0 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KDO33971.1 - 0.0017 17.9 3.7 0.0017 17.9 3.7 2.8 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 KDO33971.1 - 0.0028 17.9 3.4 0.0028 17.9 3.4 2.3 2 1 0 2 2 2 1 FYVE-type zinc finger Baculo_RING PF05883.11 KDO33971.1 - 0.027 14.5 0.1 0.027 14.5 0.1 1.5 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3H2C3 PF17122.5 KDO33971.1 - 0.053 13.6 3.6 0.053 13.6 3.6 2.9 4 1 0 4 4 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 KDO33971.1 - 2.4 8.4 16.8 3.1 8.1 4.1 3.6 2 2 2 4 4 4 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KDO33971.1 - 5.7 7.2 13.4 0.11 12.6 3.8 2.8 2 1 0 2 2 2 0 RING-variant domain CH_2 PF06294.11 KDO33972.1 - 1.4e-26 92.4 0.0 3.6e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KDO33972.1 - 1.4e-08 34.4 0.6 8.1e-07 28.8 0.0 3.1 3 0 0 3 3 3 1 CAMSAP CH domain V-ATPase_H_N PF03224.14 KDO33974.1 - 0.0079 15.5 0.0 0.054 12.8 0.0 2.1 1 1 0 1 1 1 1 V-ATPase subunit H Arm PF00514.23 KDO33974.1 - 0.022 14.8 0.2 5.1 7.3 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TetR_C_16 PF17920.1 KDO33974.1 - 0.16 12.2 3.6 0.82 9.9 0.2 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TPR_4 PF07721.14 KDO33975.1 - 0.044 14.4 0.7 0.044 14.4 0.7 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Rod_C PF10493.9 KDO33976.1 - 2.1e-30 105.6 0.6 6.1e-30 104.1 0.6 1.6 1 1 0 1 1 1 1 Rough deal protein C-terminal region Hemerythrin PF01814.23 KDO33976.1 - 1.2 9.7 6.2 0.42 11.2 1.5 2.7 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Cdc6_C PF09079.11 KDO33978.1 - 0.00028 20.8 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain HSP70 PF00012.20 KDO33979.1 - 8e-135 450.3 0.7 9.8e-135 450.1 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO33979.1 - 3e-15 55.9 0.8 3.4e-14 52.4 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 KDO33979.1 - 0.00023 19.9 0.0 0.041 12.5 0.0 2.1 2 0 0 2 2 2 2 Actin StbA PF06406.11 KDO33979.1 - 0.051 12.8 0.1 0.15 11.3 0.1 1.8 1 1 0 1 1 1 0 StbA protein FTR PF01913.18 KDO33979.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Gln-synt_N_2 PF16952.5 KDO33979.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain AA_permease_2 PF13520.6 KDO33980.1 - 8.8e-36 123.6 40.7 1.2e-35 123.1 40.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO33980.1 - 4.9e-21 74.9 31.5 7e-21 74.4 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KDO33981.1 - 9.7e-62 208.7 0.0 1.3e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO33981.1 - 1.3e-42 145.9 0.0 1.8e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO33981.1 - 1e-05 25.0 0.1 1.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO33981.1 - 2e-05 24.1 0.0 5.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO33981.1 - 0.0034 16.2 0.3 0.0079 15.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KDO33981.1 - 0.016 15.1 5.5 0.14 12.1 0.3 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KDO33981.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KDO33981.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KDO33982.1 - 1.2e-44 152.6 0.0 1.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO33982.1 - 5.2e-43 147.3 0.0 8e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 KDO33982.1 - 3.1e-07 30.6 6.6 0.0013 19.1 1.2 4.1 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO33982.1 - 1.3e-06 28.1 1.7 1.1e-05 25.1 0.4 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 KDO33982.1 - 0.00041 20.2 0.5 2.4 8.4 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KDO33982.1 - 0.074 13.6 0.4 13 6.8 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat ABC1 PF03109.16 KDO33982.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 KDO33982.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PX PF00787.24 KDO33983.1 - 8.1e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 PX domain 2-Hacid_dh_C PF02826.19 KDO33984.1 - 5.7e-52 175.6 0.0 8.6e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KDO33984.1 - 4.6e-29 100.8 0.0 6.6e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KDO33984.1 - 2.2e-05 24.1 0.2 0.00019 21.1 0.1 2.5 2 1 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 KDO33984.1 - 4.2e-05 23.8 0.1 0.0001 22.5 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KDO33984.1 - 0.016 15.3 0.4 0.039 14.0 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KDO33984.1 - 0.18 11.7 0.5 2.3 8.1 0.1 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NUDIX_2 PF13869.6 KDO33988.1 - 0.32 10.5 6.2 0.35 10.4 2.6 2.5 2 1 0 2 2 2 0 Nucleotide hydrolase MscS_porin PF12795.7 KDO33989.1 - 0.0015 18.1 25.8 0.0015 18.1 25.8 5.6 3 1 3 6 6 6 2 Mechanosensitive ion channel porin domain YueH PF14166.6 KDO33989.1 - 0.41 10.5 4.8 0.56 10.1 0.4 3.4 2 0 0 2 2 2 0 YueH-like protein Csm2_III-A PF03750.13 KDO33989.1 - 1 10.2 14.5 0.68 10.8 0.1 4.5 3 1 0 3 3 3 0 Csm2 Type III-A Ion_trans PF00520.31 KDO33990.1 - 2.3e-120 400.4 73.3 3e-36 124.9 8.1 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KDO33990.1 - 2.9e-06 26.3 67.3 0.00015 20.6 4.3 8.5 7 2 2 9 9 9 6 Polycystin cation channel GPHH PF16905.5 KDO33990.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KDO33990.1 - 0.037 13.8 0.1 0.23 11.4 0.1 2.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank_2 PF12796.7 KDO33991.1 - 8.2e-17 61.6 7.8 4.8e-07 30.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO33991.1 - 3.5e-13 49.8 10.1 0.0024 18.4 0.5 6.0 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO33991.1 - 1.8e-11 44.0 15.4 0.00025 21.3 0.2 7.1 1 1 7 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO33991.1 - 1.2e-06 28.4 6.0 0.65 10.7 0.0 6.1 7 0 0 7 7 7 2 Ankyrin repeat DUF1707 PF08044.11 KDO33991.1 - 0.1 12.7 3.5 24 5.1 0.0 5.1 5 1 1 6 6 6 0 Domain of unknown function (DUF1707) DUF411 PF04214.13 KDO33991.1 - 0.14 12.1 1.9 35 4.4 0.0 3.8 2 1 3 5 5 5 0 Protein of unknown function, DUF Ank PF00023.30 KDO33991.1 - 1.5 9.4 7.9 2.4e+02 2.4 3.6 5.1 3 1 0 3 3 3 0 Ankyrin repeat RCC1_2 PF13540.6 KDO33992.1 - 1.2e-40 136.5 52.7 7.4e-11 41.6 1.9 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KDO33992.1 - 0.0004 20.9 32.4 1.6 9.4 0.4 8.7 8 1 1 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RTBV_P12 PF06361.11 KDO33992.1 - 0.22 12.0 0.0 35 4.9 0.0 3.2 1 1 2 3 3 3 0 Rice tungro bacilliform virus P12 protein cNMP_binding PF00027.29 KDO33993.1 - 4.1e-07 30.0 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain tRNA_bind PF01588.20 KDO33995.1 - 1.5e-26 92.3 0.2 3.8e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain NAGPA PF09992.9 KDO33995.1 - 0.038 14.2 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphodiester glycosidase F5_F8_type_C PF00754.25 KDO33996.1 - 0.0021 18.2 0.8 0.24 11.5 0.0 2.7 2 1 1 3 3 3 2 F5/8 type C domain Toxin_21 PF08091.11 KDO33996.1 - 0.057 13.4 0.9 0.12 12.3 0.9 1.5 1 0 0 1 1 1 0 Spider insecticidal peptide HMG-CoA_red PF00368.18 KDO33998.1 - 4.6e-134 447.1 3.6 5.2e-134 446.9 3.6 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase zf-CCHC PF00098.23 KDO34000.1 - 0.04 14.0 1.7 0.064 13.4 1.7 1.3 1 0 0 1 1 1 0 Zinc knuckle SpecificRecomb PF10136.9 KDO34000.1 - 0.088 11.1 0.2 0.13 10.5 0.2 1.3 1 0 0 1 1 1 0 Site-specific recombinase Pkinase PF00069.25 KDO34001.1 - 9.1e-68 228.5 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34001.1 - 4.4e-34 118.0 0.0 5.4e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KDO34001.1 - 0.00058 20.5 0.1 0.0016 19.1 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KDO34001.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO34001.1 - 0.035 13.4 0.2 0.057 12.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_Packaging_2 PF11123.8 KDO34004.1 - 0.029 14.6 0.9 0.36 11.0 0.1 2.9 2 0 0 2 2 2 0 DNA packaging protein Baculo_PEP_C PF04513.12 KDO34004.1 - 2.5 8.2 16.8 8 6.5 0.4 4.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L35Ae PF01247.18 KDO34008.1 - 0.032 14.4 0.1 0.051 13.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L35Ae PH PF00169.29 KDO34009.1 - 7.3e-30 103.6 0.0 8.1e-17 61.7 0.0 2.2 1 1 1 2 2 2 2 PH domain PH_11 PF15413.6 KDO34009.1 - 4.1e-11 43.2 0.7 6.5e-05 23.3 0.3 2.9 1 1 1 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KDO34009.1 - 1.1e-05 25.7 0.3 0.0087 16.4 0.0 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain PH_12 PF16457.5 KDO34009.1 - 0.051 14.1 0.0 0.94 10.0 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain HECT PF00632.25 KDO34010.1 - 7.3e-76 255.6 0.0 9.8e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO34010.1 - 0.00018 20.7 2.0 0.00041 19.6 2.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1460 PF07313.12 KDO34010.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DZR PF12773.7 KDO34010.1 - 0.092 12.8 0.9 0.16 12.0 0.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Disintegrin PF00200.23 KDO34011.1 - 5.1e-26 91.3 101.9 2.1e-05 25.2 12.8 8.3 6 5 0 6 6 6 5 Disintegrin ARL17 PF15840.5 KDO34011.1 - 0.00072 19.9 2.2 34 4.9 0.1 5.0 4 0 0 4 4 4 3 ADP-ribosylation factor-like protein 17 TTL PF03133.15 KDO34012.1 - 5.2e-55 186.7 0.3 7.7e-55 186.1 0.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family CRAL_TRIO PF00650.20 KDO34013.1 - 9.5e-31 106.7 0.2 1.3e-30 106.2 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain 4HBT_2 PF13279.6 KDO34014.1 - 7.8e-20 71.6 0.0 1.1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KDO34014.1 - 0.014 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase 4HBT PF03061.22 KDO34014.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily ADIP PF11559.8 KDO34015.1 - 1.6e-06 28.3 12.3 1.6e-06 28.3 12.3 3.7 4 1 0 4 4 4 2 Afadin- and alpha -actinin-Binding PX PF00787.24 KDO34016.1 - 2.7e-05 24.1 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PX domain UCH PF00443.29 KDO34017.1 - 1.6e-20 73.7 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO34017.1 - 1.1e-10 41.7 0.0 4.9e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 KDO34017.1 - 0.00067 18.9 1.1 0.00067 18.9 1.1 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others PDZ PF00595.24 KDO34017.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KDO34017.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain ResB PF05140.14 KDO34018.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 ResB-like family DUF1178 PF06676.11 KDO34019.1 - 0.0043 17.4 0.0 0.0046 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) NADH-G_4Fe-4S_3 PF10588.9 KDO34019.1 - 0.027 14.0 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn-ribbon_8 PF09723.10 KDO34019.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Disintegrin PF00200.23 KDO34020.1 - 9e-11 42.4 27.0 4.5e-06 27.4 0.6 3.6 3 1 0 3 3 3 3 Disintegrin JmjC PF02373.22 KDO34021.1 - 8.8e-18 64.8 0.1 6.5e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KDO34021.1 - 1e-10 41.8 0.1 3e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Cupin-like domain F-box-like PF12937.7 KDO34021.1 - 2e-05 24.4 0.1 6.6e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like APH PF01636.23 KDO34021.1 - 0.00026 21.0 3.7 0.072 13.0 0.1 2.9 2 1 0 2 2 2 2 Phosphotransferase enzyme family Cupin_4 PF08007.12 KDO34021.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily protein PH PF00169.29 KDO34022.1 - 1.5e-07 31.9 0.0 2.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KDO34022.1 - 0.056 13.9 0.1 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KDO34024.1 - 5.5e-07 30.1 0.0 9.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 PH domain SnoaL PF07366.12 KDO34024.1 - 0.018 14.8 0.1 0.046 13.5 0.1 1.6 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase PH_15 PF17339.2 KDO34024.1 - 0.19 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 PH domain Prefoldin PF02996.17 KDO34025.1 - 3.1e-12 46.5 0.1 3.7e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1241 PF06840.11 KDO34025.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1241) Sbi-IV PF11621.8 KDO34025.1 - 0.032 14.6 2.3 0.38 11.2 0.1 2.6 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI DUF2922 PF11148.8 KDO34026.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Patched PF02460.18 KDO34027.1 - 3.7e-71 240.3 6.3 7.4e-71 239.3 6.3 1.4 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KDO34027.1 - 1.3e-42 145.3 2.0 1.3e-42 145.3 2.0 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KDO34027.1 - 0.67 8.8 39.6 0.0056 15.7 12.1 2.3 2 0 0 2 2 2 0 MMPL family CSRNP_N PF16019.5 KDO34028.1 - 5e-06 26.6 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Fib_alpha PF08702.10 KDO34029.1 - 0.0031 17.7 4.8 0.0031 17.7 4.8 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 KDO34029.1 - 0.0046 17.2 4.8 0.11 12.8 0.7 2.7 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 KDO34029.1 - 0.02 15.4 5.9 0.05 14.2 4.4 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CHDCT2 PF08074.11 KDO34029.1 - 0.2 11.8 3.6 0.64 10.2 3.6 1.9 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain NPV_P10 PF05531.12 KDO34029.1 - 0.21 12.1 6.4 0.074 13.5 0.8 2.6 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KDO34029.1 - 0.32 11.3 4.9 7.9 6.8 4.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) RPW8 PF05659.11 KDO34029.1 - 0.34 10.6 4.4 1.7 8.3 1.1 2.4 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Med9 PF07544.13 KDO34029.1 - 0.46 10.6 10.1 0.18 11.9 3.2 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spectrin PF00435.21 KDO34029.1 - 1.2 9.6 8.3 18 5.9 2.7 2.9 2 0 0 2 2 2 0 Spectrin repeat bZIP_1 PF00170.21 KDO34029.1 - 1.4 9.1 7.9 0.18 11.9 1.4 2.9 2 1 2 4 4 4 0 bZIP transcription factor CEP209_CC5 PF16574.5 KDO34029.1 - 1.8 8.7 12.9 4 7.6 12.9 1.6 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 bZIP_2 PF07716.15 KDO34029.1 - 2.2 8.4 8.4 0.46 10.6 3.5 2.5 2 0 0 2 2 2 0 Basic region leucine zipper UPF0242 PF06785.11 KDO34029.1 - 2.2 8.4 8.4 5.5 7.0 8.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KDO34029.1 - 5.1 5.6 6.0 8.5 4.9 5.3 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A BST2 PF16716.5 KDO34029.1 - 5.8 7.6 7.0 6 7.5 4.1 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 PHO4 PF01384.20 KDO34030.1 - 1.8e-67 227.8 17.1 1.8e-67 227.8 17.1 1.5 2 0 0 2 2 2 1 Phosphate transporter family PHO4 PF01384.20 KDO34031.1 - 1.3e-65 221.7 18.3 1.6e-65 221.4 18.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF2456 PF10445.9 KDO34031.1 - 0.044 13.8 1.7 10 6.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) TetR_C_14 PF17754.1 KDO34032.1 - 0.034 14.1 0.1 0.034 14.1 0.1 1.1 1 0 0 1 1 1 0 MftR C-terminal domain PspA_IM30 PF04012.12 KDO34033.1 - 0.00062 19.4 1.1 0.067 12.8 0.0 2.1 2 0 0 2 2 2 2 PspA/IM30 family Apolipoprotein PF01442.18 KDO34033.1 - 0.063 13.1 8.0 0.55 10.1 8.0 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TPPII PF12580.8 KDO34033.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II DUF3138 PF11336.8 KDO34033.1 - 0.088 11.4 1.0 0.11 11.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Syntaxin-6_N PF09177.11 KDO34033.1 - 0.21 12.1 2.3 9.4 6.9 0.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KDO34033.1 - 0.26 11.3 1.8 0.52 10.4 1.6 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 KDO34034.1 - 4.3e-08 33.6 48.2 0.025 15.1 17.4 5.1 1 1 3 4 4 4 4 YtxH-like protein Apolipoprotein PF01442.18 KDO34034.1 - 7.9e-08 32.4 29.5 0.00054 19.9 14.5 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KDO34034.1 - 3.9e-07 30.6 43.3 0.059 14.0 8.9 4.3 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 KDO34034.1 - 8.9e-06 25.7 75.5 0.073 13.2 12.1 5.8 3 1 3 6 6 6 5 Late embryogenesis abundant protein ApoLp-III PF07464.11 KDO34034.1 - 0.18 11.9 27.1 3.5 7.7 16.5 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 KDO34034.1 - 0.47 10.4 9.1 8.7 6.3 3.0 3.8 1 1 1 2 2 2 0 Apolipoprotein O Apolipoprotein PF01442.18 KDO34035.1 - 8e-09 35.6 20.7 1.1e-08 35.2 20.7 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KDO34035.1 - 0.00032 20.8 16.5 0.00063 19.9 16.1 1.6 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF4954 PF16314.5 KDO34035.1 - 0.0027 15.9 0.8 0.0034 15.6 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) OmpH PF03938.14 KDO34035.1 - 0.0028 18.0 3.9 0.0028 18.0 3.9 2.0 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) Prominin PF05478.11 KDO34035.1 - 0.0041 15.1 5.4 0.0053 14.8 5.4 1.1 1 0 0 1 1 1 1 Prominin AAA_32 PF13654.6 KDO34035.1 - 0.016 14.0 9.3 0.021 13.6 9.3 1.0 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 KDO34035.1 - 0.019 13.6 4.0 0.021 13.4 4.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_13 PF13166.6 KDO34035.1 - 0.03 13.0 10.6 0.035 12.8 10.6 1.0 1 0 0 1 1 1 0 AAA domain LMP PF04778.12 KDO34035.1 - 0.057 13.3 7.7 0.12 12.3 2.1 2.1 1 1 1 2 2 2 0 LMP repeated region DUF3584 PF12128.8 KDO34035.1 - 0.07 10.7 13.6 0.08 10.4 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CdvA PF18822.1 KDO34035.1 - 0.07 13.0 7.7 1.8 8.4 2.2 3.0 2 1 0 3 3 3 0 CdvA-like coiled-coil domain YusW PF14039.6 KDO34035.1 - 0.072 13.6 4.8 0.079 13.5 2.7 2.2 1 1 2 3 3 2 0 YusW-like protein Baculo_PEP_C PF04513.12 KDO34035.1 - 0.09 12.8 12.9 0.11 12.6 10.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus T7SS_ESX_EspC PF10824.8 KDO34035.1 - 0.099 13.1 19.8 0.72 10.4 6.1 2.3 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF883 PF05957.13 KDO34035.1 - 0.099 13.3 17.6 1.1 9.9 2.5 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 KDO34035.1 - 0.11 11.9 15.7 0.13 11.6 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gp-FAR-1 PF05823.12 KDO34035.1 - 0.13 12.6 6.3 0.3 11.4 6.3 1.6 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Urb2 PF10441.9 KDO34035.1 - 0.13 12.2 4.1 0.2 11.5 4.1 1.2 1 0 0 1 1 1 0 Urb2/Npa2 family Remorin_C PF03763.13 KDO34035.1 - 0.16 11.8 15.7 0.39 10.6 5.0 2.2 1 1 1 2 2 2 0 Remorin, C-terminal region YqhG PF11079.8 KDO34035.1 - 0.17 10.8 4.1 0.23 10.4 3.8 1.3 1 1 0 1 1 1 0 Bacterial protein YqhG of unknown function Carbpep_Y_N PF05388.11 KDO34035.1 - 0.19 12.3 5.4 0.27 11.8 4.9 1.6 1 1 0 1 1 1 0 Carboxypeptidase Y pro-peptide LUC7 PF03194.15 KDO34035.1 - 0.19 11.4 7.7 0.25 11.0 7.7 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Exonuc_VII_L PF02601.15 KDO34035.1 - 0.19 11.2 11.7 0.23 11.0 11.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_M32 PF02074.15 KDO34035.1 - 0.23 10.2 9.0 0.25 10.0 9.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Muted PF14942.6 KDO34035.1 - 0.24 11.8 12.9 2 8.8 12.9 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Tweety PF04906.13 KDO34035.1 - 0.24 10.0 6.9 0.15 10.7 4.6 1.7 1 1 1 2 2 2 0 Tweety YtxH PF12732.7 KDO34035.1 - 0.24 11.9 14.9 28 5.3 4.7 3.2 1 1 1 2 2 2 0 YtxH-like protein Phe_tRNA-synt_N PF02912.18 KDO34035.1 - 0.25 11.3 13.6 0.45 10.5 2.0 3.3 1 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain KapB PF08810.10 KDO34035.1 - 0.34 11.1 6.3 0.41 10.8 1.3 2.7 2 1 1 3 3 3 0 Kinase associated protein B Lectin_N PF03954.14 KDO34035.1 - 0.42 10.4 10.9 0.074 12.8 5.0 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 KDO34035.1 - 0.5 10.4 9.8 3.1 7.9 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KDO34035.1 - 0.83 9.8 10.1 1.5 9.0 4.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YlqD PF11068.8 KDO34035.1 - 0.9 9.9 12.6 1.5 9.2 12.4 1.5 1 1 0 1 1 1 0 YlqD protein DUF1690 PF07956.11 KDO34035.1 - 1 9.8 12.9 3.8 7.9 6.4 1.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Spore_SspJ PF09575.10 KDO34035.1 - 1.2 9.6 4.9 0.43 11.0 0.7 2.2 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) GAT PF03127.14 KDO34035.1 - 1.8 8.9 7.9 3.6 8.0 0.2 2.9 1 1 2 3 3 3 0 GAT domain DUF3080 PF11279.8 KDO34035.1 - 1.8 7.7 13.9 2.9 7.0 13.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) YabA PF06156.13 KDO34035.1 - 1.9 9.2 6.1 8.6 7.1 6.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA HSCB_C PF07743.13 KDO34035.1 - 1.9 9.0 17.5 11 6.6 6.7 3.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain UPF0242 PF06785.11 KDO34035.1 - 2.1 8.4 13.8 2.9 7.9 3.8 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CTU2 PF10288.9 KDO34035.1 - 2.6 8.3 10.1 5.7 7.2 10.1 1.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 NPV_P10 PF05531.12 KDO34035.1 - 2.7 8.5 8.8 2.7 8.5 4.9 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tape_meas_lam_C PF09718.10 KDO34035.1 - 2.8 8.2 10.1 8.5 6.6 0.3 2.8 2 2 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) COG2 PF06148.11 KDO34035.1 - 3 7.9 9.1 1.1 9.4 3.2 2.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1682 PF07946.14 KDO34035.1 - 4.1 6.5 12.8 0.017 14.4 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) CheZ PF04344.13 KDO34035.1 - 5 7.0 13.2 13 5.6 12.6 1.9 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ Phage_Mu_Gam PF07352.12 KDO34035.1 - 5.1 7.0 13.3 11 5.9 4.6 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein HisKA_3 PF07730.13 KDO34035.1 - 5.8 7.5 10.5 18 5.9 4.7 2.9 2 1 0 2 2 2 0 Histidine kinase PIN_8 PF18476.1 KDO34035.1 - 5.9 6.7 8.9 16 5.3 8.9 1.7 1 1 0 1 1 1 0 PIN like domain HU-CCDC81_bac_2 PF18175.1 KDO34035.1 - 6.7 6.7 6.2 6.6 6.7 0.4 3.1 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 TMPIT PF07851.13 KDO34035.1 - 7 5.8 9.2 14 4.8 9.2 1.6 1 1 0 1 1 1 0 TMPIT-like protein CSN5_C PF18323.1 KDO34035.1 - 7.3 7.6 9.2 22 6.1 0.4 2.3 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Nup54 PF13874.6 KDO34035.1 - 7.6 6.6 13.0 0.56 10.3 5.8 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF5403 PF17395.2 KDO34035.1 - 8.4 6.8 7.7 1.9 8.8 0.9 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5403) DUF2203 PF09969.9 KDO34035.1 - 9.4 7.0 11.4 1.8 9.3 3.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_C48 PF02902.19 KDO34036.1 - 5.2e-21 75.5 0.0 8.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain hNIFK_binding PF12196.8 KDO34036.1 - 0.2 11.1 2.4 0.39 10.3 0.5 2.5 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Pkinase PF00069.25 KDO34037.1 - 1e-67 228.3 0.0 1.3e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34037.1 - 3.2e-35 121.7 0.0 4.3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO34037.1 - 1.1e-05 24.9 0.2 2e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO34037.1 - 0.00045 19.1 0.0 0.0011 17.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KDO34037.1 - 0.0075 15.9 0.3 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KDO34037.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DEAD PF00270.29 KDO34038.1 - 1.8e-12 47.4 0.0 4.9e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KDO34038.1 - 1.3e-05 25.3 0.0 0.00038 20.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KDO34038.1 - 0.15 11.1 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CENP-B_dimeris PF09026.10 KDO34038.1 - 5.1 7.5 7.4 6.3 7.2 4.5 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 KDO34039.1 - 8.9e-09 35.8 0.2 0.0025 18.4 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34039.1 - 1.1e-08 35.5 0.3 1.4e-06 28.8 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34039.1 - 0.0006 20.1 0.1 0.085 13.2 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34039.1 - 0.0028 18.0 0.1 0.79 10.5 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat PH PF00169.29 KDO34040.1 - 4.7e-10 39.9 0.0 9.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KDO34040.1 - 0.00067 19.9 0.9 0.0028 17.9 0.9 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KDO34040.1 - 0.0038 17.6 2.2 0.051 14.0 2.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 KDO34040.1 - 0.058 13.1 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 PH domain SPRY PF00622.28 KDO34041.1 - 7e-21 74.6 1.6 2.5e-14 53.4 0.1 3.3 2 1 1 3 3 3 3 SPRY domain HECT PF00632.25 KDO34041.1 - 4e-18 65.9 0.0 1.4e-17 64.2 0.0 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.6 KDO34041.1 - 6.9e-05 23.0 0.0 0.00041 20.5 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily RCC1 PF00415.18 KDO34042.1 - 6.6e-75 247.6 22.0 2.4e-13 50.5 0.3 8.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO34042.1 - 7.9e-33 111.6 47.2 2.9e-08 33.3 3.4 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 KDO34042.1 - 0.13 12.5 2.3 6.9 7.0 0.0 3.4 3 1 0 3 3 3 0 Putative heavy-metal chelation DUF4419 PF14388.6 KDO34045.1 - 8.9e-96 320.9 0.0 1e-95 320.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) CHAP PF05257.16 KDO34047.1 - 1.2e-12 48.2 0.0 2.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 CHAP domain POR PF01558.18 KDO34047.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase HPS3_Mid PF14762.6 KDO34049.1 - 0.26 10.0 0.5 0.42 9.3 0.5 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region CENP-B_dimeris PF09026.10 KDO34050.1 - 0.85 10.0 34.8 0.054 13.9 9.8 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 KDO34051.1 - 5.7e-20 71.7 16.9 2.3e-06 28.1 0.3 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34051.1 - 1.3e-18 67.1 3.9 0.00092 19.7 0.0 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34051.1 - 3.2e-12 46.4 10.6 0.13 12.6 0.0 8.1 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34051.1 - 3.6e-07 30.0 0.7 3.5 8.5 0.0 7.8 9 0 0 9 9 9 1 Ankyrin repeat Ank PF00023.30 KDO34051.1 - 5.9e-05 23.3 2.8 2.7 8.6 0.0 6.8 3 2 0 3 3 3 1 Ankyrin repeat DUF1707 PF08044.11 KDO34051.1 - 0.0095 16.0 12.4 31 4.7 0.1 6.7 3 1 4 7 7 7 0 Domain of unknown function (DUF1707) Ank_2 PF12796.7 KDO34052.1 - 0.0014 19.2 0.4 0.0032 18.0 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF1843 PF08898.10 KDO34052.1 - 0.0073 16.8 0.4 0.02 15.4 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Ank_3 PF13606.6 KDO34052.1 - 0.15 12.7 0.3 31 5.6 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeat H2TH PF06831.14 KDO34052.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain EamA PF00892.20 KDO34054.1 - 1e-07 32.2 26.1 6.8e-05 23.1 5.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 KDO34055.1 - 4.4e-13 49.6 5.4 8.2e-06 26.3 0.1 5.5 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34055.1 - 1.9e-07 31.2 10.0 10 6.6 0.0 9.0 7 2 3 10 10 10 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO34055.1 - 3.1e-06 27.6 16.8 0.41 11.3 0.1 7.7 6 3 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34055.1 - 4.2e-06 26.7 5.2 15 6.5 0.0 8.5 9 0 0 9 9 9 1 Ankyrin repeat Glycos_transf_1 PF00534.20 KDO34058.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 2-ph_phosp PF04029.14 KDO34058.1 - 0.019 14.1 0.2 0.037 13.2 0.2 1.3 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase Glyco_trans_1_4 PF13692.6 KDO34058.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ank_2 PF12796.7 KDO34060.1 - 1.1e-21 77.2 17.2 2.1e-06 28.2 0.4 6.3 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34060.1 - 8.6e-16 58.1 21.6 3.5e-05 24.3 0.3 7.9 5 4 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34060.1 - 6.9e-11 42.2 21.0 0.0012 19.2 0.2 8.9 5 3 5 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34060.1 - 6.9e-08 32.2 13.1 0.15 12.7 0.0 10.0 13 0 0 13 13 13 2 Ankyrin repeat DUF249 PF03158.13 KDO34060.1 - 0.014 15.1 0.0 3.4 7.3 0.0 3.3 3 1 0 3 3 3 0 Multigene family 530 protein Ank PF00023.30 KDO34060.1 - 0.75 10.3 18.6 2 9.0 0.2 7.1 7 2 0 7 7 7 0 Ankyrin repeat GST_N PF02798.20 KDO34061.1 - 6.2e-17 61.7 0.1 1.6e-16 60.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO34061.1 - 4.4e-15 55.8 0.1 7.9e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO34061.1 - 2.1e-13 50.4 0.0 4.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO34061.1 - 6.1e-08 32.8 0.0 1.8e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO34061.1 - 0.0032 17.4 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO34061.1 - 0.022 15.0 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KDO34061.1 - 0.023 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin DUF4278 PF14105.6 KDO34061.1 - 0.086 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) GST_N PF02798.20 KDO34062.1 - 6.7e-16 58.4 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO34062.1 - 2.7e-13 50.1 0.0 4.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO34062.1 - 5.9e-12 45.7 0.0 9.7e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO34062.1 - 8.4e-08 32.3 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO34062.1 - 1e-06 28.6 0.0 6.6e-06 26.1 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO34062.1 - 8e-05 22.8 0.0 0.00016 21.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KDO34063.1 - 4.2e-14 52.7 0.0 7.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KDO34063.1 - 5.7e-14 52.2 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KDO34063.1 - 7.3e-11 42.2 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KDO34063.1 - 4.9e-07 29.9 0.0 8.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO34063.1 - 1.7e-06 27.9 0.1 4.7e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KDO34063.1 - 0.0059 16.8 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PI3_PI4_kinase PF00454.27 KDO34064.1 - 1.1e-49 169.5 0.0 3.3e-48 164.7 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KDO34064.1 - 2.3e-32 111.9 1.5 3.9e-32 111.1 1.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 KDO34064.1 - 1.4e-07 31.6 0.0 1.2e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KDO34064.1 - 8.1e-05 22.6 0.0 0.00052 19.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KDO34064.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Nudc_N PF14050.6 KDO34065.1 - 4.2e-23 81.1 0.1 6.1e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 KDO34065.1 - 1e-15 58.5 0.0 1.5e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF2963 PF11178.8 KDO34065.1 - 0.047 13.4 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) RNA_ligase PF09414.10 KDO34067.1 - 6.5e-16 59.1 0.0 1e-15 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA ligase YcgR PF07317.12 KDO34069.1 - 0.063 13.1 0.2 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Flagellar regulator YcgR FAM25 PF15825.5 KDO34069.1 - 2.2 8.7 3.8 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 FAM25 family CUE PF02845.16 KDO34070.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain GYF PF02213.16 KDO34071.1 - 5.2e-11 42.0 0.1 1.3e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 GYF domain Fcf1 PF04900.12 KDO34072.1 - 7.9e-39 132.1 2.6 1.5e-38 131.2 2.6 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KDO34072.1 - 1.1e-10 41.8 0.1 2.2e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 PIN like domain PITH PF06201.13 KDO34073.1 - 1.1e-37 129.6 0.0 1.3e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain zf-RING_5 PF14634.6 KDO34075.1 - 3.7e-05 23.6 12.4 8e-05 22.5 12.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain NapB PF03892.14 KDO34075.1 - 1.6 8.7 5.4 0.37 10.8 0.6 2.4 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) zf-C2HC5 PF06221.13 KDO34075.1 - 7.4 6.6 13.1 20 5.2 3.9 3.0 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type Acetyltransf_9 PF13527.7 KDO34077.1 - 0.0074 16.4 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KDO34077.1 - 0.032 13.7 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_1 PF00583.25 KDO34077.1 - 0.094 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4833 PF16117.5 KDO34080.1 - 3.4e-13 49.8 0.0 5.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) PX PF00787.24 KDO34080.1 - 1.6e-06 28.1 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 PX domain START PF01852.19 KDO34080.1 - 2.5e-06 27.1 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 START domain Cellulase PF00150.18 KDO34083.1 - 1.3e-20 74.0 0.4 1.9e-20 73.4 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ricin_B_lectin PF00652.22 KDO34083.1 - 3.1e-20 72.7 3.6 2.3e-09 37.6 0.1 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO34083.1 - 3e-05 24.7 0.3 0.016 15.9 0.1 3.2 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Barwin PF00967.17 KDO34083.1 - 0.022 14.6 0.1 0.068 13.0 0.1 1.8 1 0 0 1 1 1 0 Barwin family DUF3995 PF13160.6 KDO34083.1 - 0.071 13.5 1.5 0.35 11.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Ezh2_MCSS PF18600.1 KDO34083.1 - 0.18 11.4 1.5 0.5 10.0 1.5 1.7 1 0 0 1 1 1 0 MCSS domain LicD PF04991.13 KDO34084.1 - 1.8e-18 67.5 0.0 4.7e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 LicD family LicD PF04991.13 KDO34085.1 - 8.5e-07 29.3 0.0 0.046 13.8 0.0 2.1 2 0 0 2 2 2 2 LicD family LicD PF04991.13 KDO34086.1 - 8e-13 49.0 1.1 1e-12 48.7 0.1 1.7 2 1 0 2 2 2 1 LicD family Ank_2 PF12796.7 KDO34087.1 - 6.8e-09 36.2 1.4 3e-06 27.7 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34087.1 - 1.1e-06 29.1 0.3 0.00019 21.9 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34087.1 - 3.5e-06 26.9 0.5 1.1 10.1 0.1 4.0 2 2 2 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO34087.1 - 0.00019 21.7 0.6 0.46 11.0 0.1 3.5 1 1 2 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KDO34087.1 - 0.00059 20.1 0.3 0.98 9.8 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FancD2 PF14631.6 KDO34088.1 - 0.031 11.7 2.4 0.048 11.1 2.4 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PMD PF10536.9 KDO34088.1 - 0.13 11.3 1.8 0.23 10.5 1.8 1.3 1 0 0 1 1 1 0 Plant mobile domain TetR_C_15 PF17918.1 KDO34089.1 - 0.058 14.1 2.7 1.3 9.8 0.1 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Thymopoietin PF08198.11 KDO34089.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Thymopoietin protein DNA_pol3_alpha PF07733.12 KDO34089.1 - 0.11 12.1 0.1 2.2 7.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain Ring_hydroxyl_B PF00866.18 KDO34089.1 - 0.27 11.3 1.3 0.61 10.1 1.3 1.5 1 0 0 1 1 1 0 Ring hydroxylating beta subunit DUF3883 PF13020.6 KDO34090.1 - 1.1e-18 67.1 0.0 3.2e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) DUF4131 PF13567.6 KDO34091.1 - 1.6 8.3 5.9 12 5.5 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) BK_channel_a PF03493.18 KDO34092.1 - 1.3e-18 67.0 0.0 5.9e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO34092.1 - 5.7e-12 45.4 0.9 5.7e-12 45.4 0.9 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KDO34092.1 - 1.7e-11 43.8 6.4 3.1e-11 43.0 6.4 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO34092.1 - 8.5e-06 26.0 0.0 0.0032 17.7 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain DUF973 PF06157.11 KDO34092.1 - 1.1 8.3 5.3 0.29 10.1 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF973) Glyoxalase PF00903.25 KDO34093.1 - 4.8e-11 43.0 0.0 6.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KDO34093.1 - 8.5e-06 26.0 0.0 1.2e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO34093.1 - 0.075 13.8 0.0 0.097 13.5 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain YmgD PF16456.5 KDO34093.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 YmgD protein F-box-like PF12937.7 KDO34094.1 - 0.061 13.2 1.6 0.16 11.9 1.6 1.8 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 KDO34094.1 - 0.13 12.2 1.0 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 F-box domain DUF5525 PF17663.1 KDO34095.1 - 0.013 13.6 1.3 0.014 13.5 1.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Zw10 PF06248.13 KDO34096.1 - 2.1e-23 82.8 7.6 1e-21 77.1 6.7 3.3 1 1 1 2 2 2 1 Centromere/kinetochore Zw10 UCH PF00443.29 KDO34099.1 - 3.3e-22 79.2 0.0 2.3e-21 76.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO34099.1 - 9e-13 48.5 5.5 1.3e-11 44.6 0.1 2.9 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KDO34099.1 - 0.003 17.1 0.1 0.0071 15.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Phage_GP20 PF06810.11 KDO34099.1 - 0.29 10.9 9.1 4.9 7.0 0.3 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 CASP_C PF08172.12 KDO34099.1 - 0.33 10.2 13.4 0.012 14.9 5.7 2.1 2 0 0 2 2 2 0 CASP C terminal DUF4407 PF14362.6 KDO34099.1 - 0.46 9.8 18.3 0.91 8.8 18.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Myosin_head PF00063.21 KDO34100.1 - 2.2e-11 42.7 0.0 2.6e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Aida_C2 PF14186.6 KDO34101.1 - 4.3e-25 88.1 0.0 6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal adhesion Ank_5 PF13857.6 KDO34101.1 - 4e-07 30.2 0.0 7.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO34101.1 - 0.00099 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34101.1 - 0.046 14.3 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO34101.1 - 0.065 13.8 0.0 0.21 12.2 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeat Presenilin PF01080.17 KDO34104.1 - 0.38 9.5 4.5 0.43 9.3 4.5 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KDO34104.1 - 5 5.8 8.0 6.3 5.5 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 KDO34104.1 - 10 6.2 6.7 14 5.7 6.7 1.2 1 0 0 1 1 1 0 DDHD domain SHE3 PF17078.5 KDO34106.1 - 0.0026 17.5 20.2 0.083 12.6 0.5 2.5 2 1 0 2 2 2 2 SWI5-dependent HO expression protein 3 Filament PF00038.21 KDO34106.1 - 0.029 14.0 27.0 0.23 11.0 19.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 KDO34106.1 - 0.071 13.6 8.4 2.1 8.8 0.2 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF244 PF03112.14 KDO34106.1 - 0.19 11.6 1.8 0.34 10.7 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein family (ORF7) DUF FlaC_arch PF05377.11 KDO34106.1 - 0.26 11.7 2.7 11 6.6 0.1 3.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) ApoO PF09769.9 KDO34106.1 - 2.3 8.2 6.8 4.6 7.2 0.9 3.4 2 1 2 4 4 4 0 Apolipoprotein O DUF4874 PF16173.5 KDO34106.1 - 2.9 7.6 6.4 1.5 8.5 2.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4874) TINF2_N PF14973.6 KDO34106.1 - 5.6 7.3 15.2 13 6.2 0.1 3.3 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus FUSC PF04632.12 KDO34106.1 - 6.1 5.2 21.4 1.7 7.1 11.7 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF5401 PF17380.2 KDO34106.1 - 8.6 4.3 29.0 16 3.4 28.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5401) Pkinase_Tyr PF07714.17 KDO34107.1 - 9.2e-35 120.2 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34107.1 - 3.7e-31 108.5 0.0 5.2e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Lebercilin PF15619.6 KDO34109.1 - 0.0019 17.9 1.0 0.0019 17.9 1.0 4.7 3 1 2 5 5 5 1 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.9 KDO34109.1 - 0.0032 17.7 0.1 0.0032 17.7 0.1 2.6 2 1 1 3 3 3 1 Golgi transport complex subunit 5 DUF5082 PF16888.5 KDO34109.1 - 0.013 15.8 13.2 0.05 13.9 5.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Cauli_AT PF03233.13 KDO34109.1 - 0.13 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Aphid transmission protein Sec5 PF15469.6 KDO34109.1 - 0.19 11.5 3.2 2.3 8.0 0.1 3.0 2 1 1 3 3 3 0 Exocyst complex component Sec5 PDZ_assoc PF10600.9 KDO34109.1 - 0.28 12.0 12.4 0.63 10.9 1.2 3.4 1 1 2 3 3 3 0 PDZ-associated domain of NMDA receptors Baculo_PEP_C PF04513.12 KDO34109.1 - 0.77 9.8 5.7 2.5 8.1 1.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KDO34109.1 - 0.93 9.5 8.5 8.6 6.4 0.5 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KDO34109.1 - 1.1 9.7 36.9 0.15 12.5 18.5 3.6 1 1 1 2 2 2 0 Fez1 LPP PF04728.13 KDO34109.1 - 2.7 8.4 6.6 2.8 8.4 0.1 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 KDO34109.1 - 5 7.5 13.0 0.3 11.4 0.3 3.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 adh_short_C2 PF13561.6 KDO34110.1 - 7.4e-53 179.5 0.1 9.7e-53 179.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO34110.1 - 1e-49 168.6 0.1 1.3e-49 168.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO34110.1 - 9.4e-09 35.4 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain FTR PF01913.18 KDO34110.1 - 0.018 15.0 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Med27 PF11571.8 KDO34111.1 - 7e-21 74.4 0.7 2e-20 73.0 0.7 1.8 1 0 0 1 1 1 1 Mediator complex subunit 27 6PF2K PF01591.18 KDO34111.1 - 0.3 10.4 1.5 0.53 9.6 0.0 2.1 3 0 0 3 3 3 0 6-phosphofructo-2-kinase IBR PF01485.21 KDO34113.1 - 1.9e-11 44.0 30.3 1.1e-07 32.0 12.2 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KDO34113.1 - 1.3e-06 28.3 3.2 1.3e-06 28.3 3.2 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KDO34113.1 - 5.5e-05 23.0 1.5 5.5e-05 23.0 1.5 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO34113.1 - 0.0013 19.0 7.3 0.0013 19.0 7.3 4.1 2 2 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 KDO34113.1 - 0.0018 18.4 0.4 0.0018 18.4 0.4 4.8 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING Copine PF07002.16 KDO34114.1 - 6.7e-56 189.2 0.0 8.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 KDO34114.1 - 5.6e-09 35.7 8.9 5.6e-09 35.7 8.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) vWA-TerF-like PF10138.9 KDO34114.1 - 0.00029 21.0 0.2 0.0015 18.7 0.2 2.0 1 1 0 1 1 1 1 vWA found in TerF C terminus zf-C3HC4_2 PF13923.6 KDO34114.1 - 0.0011 18.8 12.5 0.0011 18.8 12.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO34114.1 - 0.049 14.0 13.4 0.096 13.0 11.0 2.5 2 0 0 2 2 2 0 Ring finger domain DUF2039 PF10217.9 KDO34114.1 - 0.061 13.7 4.7 0.14 12.5 4.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 KDO34114.1 - 0.081 12.9 13.3 1.4 9.0 13.3 2.5 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO34114.1 - 0.094 12.6 11.0 0.86 9.5 11.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KDO34114.1 - 0.13 12.5 6.4 0.97 9.6 6.6 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 KDO34114.1 - 0.18 11.9 3.0 0.36 10.9 3.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C3HC4 PF00097.25 KDO34114.1 - 0.85 9.5 17.5 0.048 13.5 11.1 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 KDO34114.1 - 5.4 6.7 14.5 1.1 8.8 0.2 3.4 3 0 0 3 3 3 0 RecR protein FYVE PF01363.21 KDO34115.1 - 8.3e-17 61.1 25.6 1.2e-12 47.8 8.5 2.5 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 KDO34115.1 - 3.1e-06 27.4 17.0 0.003 17.7 5.6 2.4 2 0 0 2 2 2 2 FYVE-type zinc finger Rad50_zn_hook PF04423.14 KDO34115.1 - 0.045 13.6 0.3 0.14 12.1 0.3 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif GAF PF01590.26 KDO34117.1 - 4.2e-05 24.2 0.0 4.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 GAF domain Peptidase_S29 PF02907.15 KDO34117.1 - 0.00049 19.9 0.0 0.00054 19.7 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease FYVE PF01363.21 KDO34118.1 - 3.2e-19 68.8 42.9 2.4e-10 40.4 18.3 2.6 1 1 1 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 KDO34118.1 - 0.00017 21.8 33.1 0.16 12.2 17.4 2.5 1 1 1 2 2 2 2 FYVE-type zinc finger BaffR-Tall_bind PF09256.10 KDO34118.1 - 0.23 11.3 8.7 0.35 10.7 0.7 3.1 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding FYVE PF01363.21 KDO34119.1 - 1.8e-21 76.1 39.5 2.5e-11 43.5 14.9 2.5 2 0 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 KDO34119.1 - 6.4e-10 39.8 0.2 1.9e-09 38.3 0.1 1.9 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO34119.1 - 9.1e-05 22.7 21.7 0.00065 19.9 5.1 2.5 2 0 0 2 2 2 2 FYVE-type zinc finger FYVE PF01363.21 KDO34120.1 - 3.3e-05 23.9 21.2 8.6e-05 22.6 21.2 1.6 1 1 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34120.1 - 3.5e-05 24.4 0.0 6.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO34120.1 - 0.0026 18.0 11.2 0.0047 17.1 11.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger MGC-24 PF05283.11 KDO34121.1 - 0.012 16.1 2.4 0.023 15.2 2.4 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FYVE PF01363.21 KDO34122.1 - 7.5e-25 86.9 89.6 1.6e-08 34.5 11.2 5.9 6 0 0 6 6 6 5 FYVE zinc finger FYVE PF01363.21 KDO34123.1 - 2.9e-20 72.2 33.2 9.9e-15 54.4 13.2 2.4 2 0 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 KDO34123.1 - 2e-07 31.7 0.2 8.6e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO34123.1 - 0.00061 20.0 25.2 0.014 15.6 8.1 2.2 2 0 0 2 2 2 2 FYVE-type zinc finger GAF_3 PF13492.6 KDO34123.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 GAF domain FYVE PF01363.21 KDO34124.1 - 1.3e-49 166.2 54.5 2.9e-14 52.9 9.2 4.2 4 0 0 4 4 4 4 FYVE zinc finger FYVE_2 PF02318.16 KDO34124.1 - 6.7e-11 42.4 39.6 0.0042 17.3 4.0 4.3 4 0 0 4 4 4 4 FYVE-type zinc finger GAF PF01590.26 KDO34124.1 - 5.6e-07 30.3 0.0 1.6e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain Elf1 PF05129.13 KDO34124.1 - 0.027 14.5 2.0 0.027 14.5 2.0 5.1 4 2 1 5 5 5 0 Transcription elongation factor Elf1 like GAF_3 PF13492.6 KDO34124.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain IncF PF17626.2 KDO34125.1 - 0.57 10.6 6.6 0.12 12.7 2.6 1.9 2 0 0 2 2 2 0 Inclusion membrane protein F DSPc PF00782.20 KDO34126.1 - 1.1e-29 102.9 0.0 1.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO34126.1 - 0.0068 16.0 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KDO34126.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family WD40 PF00400.32 KDO34128.1 - 5.9e-20 71.2 18.6 0.00048 20.9 0.0 9.4 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34128.1 - 5.2e-11 42.7 1.4 0.00013 22.2 0.0 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO34128.1 - 0.00012 21.1 1.9 0.29 10.0 0.3 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_7 PF13499.6 KDO34128.1 - 0.0006 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KDO34128.1 - 0.00061 19.1 0.0 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KDO34128.1 - 0.0021 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 KDO34128.1 - 0.0053 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 KDO34128.1 - 0.012 15.5 0.0 0.038 13.9 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 KDO34128.1 - 0.021 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair PQQ_2 PF13360.6 KDO34128.1 - 0.048 13.2 1.4 0.11 12.0 0.6 2.0 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KDO34128.1 - 0.56 8.8 5.4 2 7.0 0.1 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 LRR_4 PF12799.7 KDO34129.1 - 3e-58 192.8 88.5 3.6e-07 30.4 5.4 15.4 11 4 2 15 15 15 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO34129.1 - 2.5e-57 193.1 26.9 1.1e-12 47.8 4.7 8.1 3 2 5 8 8 8 7 Leucine-rich repeat LRR_8 PF13855.6 KDO34129.1 - 6.6e-43 144.3 85.0 4.2e-07 29.6 3.0 11.9 8 2 4 12 12 12 12 Leucine rich repeat LRR_6 PF13516.6 KDO34129.1 - 0.0019 18.1 68.2 2.5 8.4 0.4 18.6 18 1 1 19 19 19 3 Leucine Rich repeat HTH_46 PF15977.5 KDO34129.1 - 0.055 13.5 0.2 0.34 10.9 0.0 2.5 2 1 0 2 2 2 0 Winged helix-turn-helix DNA binding LRR_2 PF07723.13 KDO34129.1 - 0.13 13.0 2.5 20 6.1 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat RNase_P_p30 PF01876.16 KDO34130.1 - 1.5e-31 109.5 0.0 2e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 CBFD_NFYB_HMF PF00808.23 KDO34131.1 - 8.6e-08 32.4 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NOA36 PF06524.12 KDO34131.1 - 1.5 8.1 9.2 1.6 8.0 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein Iso_dh PF00180.20 KDO34132.1 - 3.4e-72 243.5 0.0 4e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 KDO34132.1 - 0.11 13.2 0.7 0.48 11.2 0.2 2.2 2 0 0 2 2 2 0 Phenylalanine zipper Ank_4 PF13637.6 KDO34133.1 - 1.4e-33 114.8 9.6 8.2e-08 32.6 0.1 5.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34133.1 - 8.9e-33 112.7 0.7 6.3e-14 52.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34133.1 - 1.9e-28 98.2 3.8 9.9e-09 35.3 0.1 6.2 4 3 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34133.1 - 3.4e-25 85.3 1.0 2.5e-06 27.4 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KDO34133.1 - 2.6e-23 81.4 9.5 3.6e-07 30.3 0.3 6.3 4 2 1 5 5 5 5 Ankyrin repeat VWA_3_C PF18571.1 KDO34133.1 - 0.0021 17.9 0.7 9.9 6.1 0.0 3.9 4 0 0 4 4 4 2 von Willebrand factor type A C-terminal domain Ribosomal_L10 PF00466.20 KDO34134.1 - 1.6e-22 79.5 0.0 3.2e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KDO34134.1 - 3.1e-20 71.9 0.1 8.6e-20 70.5 0.1 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KDO34134.1 - 1.4e-09 38.4 7.6 2.5e-09 37.6 7.6 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 KDO34135.1 - 8.5e-32 108.9 0.1 1.2e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 LCAT PF02450.15 KDO34135.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase zf-B_box PF00643.24 KDO34136.1 - 2.5e-09 37.1 31.5 2.5e-06 27.5 3.1 3.5 2 1 1 3 3 3 3 B-box zinc finger IQ PF00612.27 KDO34136.1 - 6.2e-09 34.9 95.6 0.0044 16.7 1.7 13.4 12 0 0 12 12 12 8 IQ calmodulin-binding motif p25-alpha PF05517.12 KDO34136.1 - 1.3e-07 31.9 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 p25-alpha Ribosomal_L40e PF01020.17 KDO34136.1 - 3.6 7.5 8.8 3.5 7.6 1.3 3.2 2 0 0 2 2 2 0 Ribosomal L40e family FYVE PF01363.21 KDO34137.1 - 5.6e-17 61.6 10.6 1.7e-16 60.1 10.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO34137.1 - 0.035 14.3 4.4 0.082 13.1 4.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KDO34137.1 - 8.4 6.6 14.1 4.9 7.4 9.9 2.7 2 1 0 2 2 2 0 B-box zinc finger Med9 PF07544.13 KDO34138.1 - 5.6e-13 48.8 0.3 7.2e-13 48.4 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KDO34138.1 - 0.037 14.3 0.8 0.049 13.9 0.5 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Peptidase_M14 PF00246.24 KDO34139.1 - 8e-41 140.7 0.0 1e-40 140.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase FYVE PF01363.21 KDO34140.1 - 1.6e-18 66.6 9.6 3e-18 65.7 9.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34140.1 - 8.7e-08 32.9 0.0 1.7e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain C1_2 PF03107.16 KDO34140.1 - 0.033 14.5 6.5 0.075 13.4 6.5 1.6 1 0 0 1 1 1 0 C1 domain GAF_3 PF13492.6 KDO34140.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 GAF domain FYVE_2 PF02318.16 KDO34140.1 - 0.75 10.0 6.8 1.7 8.9 6.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Zf_RING PF16744.5 KDO34140.1 - 4.1 7.6 9.2 11 6.2 9.2 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger FYVE PF01363.21 KDO34141.1 - 2.5e-31 107.6 42.8 4.8e-11 42.6 8.3 3.4 3 0 0 3 3 3 3 FYVE zinc finger GAF PF01590.26 KDO34141.1 - 2.6e-07 31.3 0.2 1.5e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KDO34141.1 - 1.7e-05 25.2 0.0 3.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 KDO34141.1 - 0.00012 22.2 33.5 0.073 13.3 4.5 3.8 4 0 0 4 4 4 3 FYVE-type zinc finger GAF_3 PF13492.6 KDO34141.1 - 0.0013 19.0 0.0 0.0035 17.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain IBR PF01485.21 KDO34141.1 - 0.024 14.9 29.1 0.22 11.8 3.3 4.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DnaJ_CXXCXGXG PF00684.19 KDO34141.1 - 0.71 10.3 18.3 1.3 9.4 0.2 4.5 5 0 0 5 5 5 0 DnaJ central domain zf-C2HE PF16278.5 KDO34141.1 - 7.7 7.1 8.4 8.2 7.0 3.4 3.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 KDO34143.1 - 8.8e-22 77.0 39.0 3.8e-08 33.3 6.2 3.3 3 0 0 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.16 KDO34143.1 - 5.6e-08 33.0 28.5 0.0016 18.7 1.4 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger RMI2 PF16100.5 KDO34144.1 - 1.7e-17 63.5 0.1 4.7e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 FHA PF00498.26 KDO34144.1 - 4.5e-14 52.6 0.2 1e-13 51.4 0.1 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KDO34144.1 - 2.6e-05 24.4 0.2 0.002 18.4 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain IQ PF00612.27 KDO34144.1 - 0.0022 17.7 0.4 0.011 15.5 0.1 6.2 6 0 0 6 6 6 3 IQ calmodulin-binding motif FYVE PF01363.21 KDO34145.1 - 1.2e-16 60.6 12.5 2.2e-16 59.8 12.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34145.1 - 5.8e-08 33.4 0.0 1.2e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KDO34145.1 - 0.0069 16.7 0.0 0.021 15.2 0.0 1.8 1 1 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 KDO34145.1 - 0.031 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Peptidase_S29 PF02907.15 KDO34145.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease C1_2 PF03107.16 KDO34145.1 - 0.17 12.2 5.0 0.46 10.8 5.0 1.7 1 0 0 1 1 1 0 C1 domain FYVE PF01363.21 KDO34146.1 - 1.8e-16 60.0 12.7 3.5e-16 59.1 12.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34146.1 - 1.3e-08 35.6 0.0 3.2e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KDO34146.1 - 0.0024 18.2 0.0 0.0082 16.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain Zf_RING PF16744.5 KDO34146.1 - 1.5 9.0 11.8 7.3 6.8 11.8 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger SHQ1 PF04925.15 KDO34147.1 - 2.2e-51 173.9 0.1 3.7e-51 173.2 0.1 1.3 1 0 0 1 1 1 1 SHQ1 protein FYVE PF01363.21 KDO34148.1 - 1.9e-08 34.3 14.3 1.9e-08 34.3 14.3 2.1 2 1 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 KDO34148.1 - 9.3e-06 26.3 0.0 1.8e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain Med13_C PF06333.12 KDO34148.1 - 0.016 14.5 0.0 0.016 14.5 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain FYVE_2 PF02318.16 KDO34148.1 - 0.058 13.6 7.5 0.23 11.7 7.5 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger SpoVT_C PF15714.5 KDO34148.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Dzip-like_N PF13815.6 KDO34148.1 - 0.11 12.5 2.6 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2HC5 PF06221.13 KDO34148.1 - 3.9 7.5 13.7 12 6.0 11.9 2.5 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE PF01363.21 KDO34149.1 - 2.6e-07 30.7 6.1 7.3e-07 29.2 6.1 1.8 1 1 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34149.1 - 0.00027 21.6 0.0 0.00079 20.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KDO34149.1 - 0.0011 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO34149.1 - 0.0012 19.2 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain RRXRR PF14239.6 KDO34149.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 RRXRR protein FYVE PF01363.21 KDO34150.1 - 2.4e-18 66.0 11.3 5e-18 65.0 11.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34150.1 - 3.4e-10 40.7 0.0 8.7e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KDO34150.1 - 2.7e-07 30.9 0.0 9.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KDO34150.1 - 0.053 13.9 0.0 0.63 10.4 0.0 2.3 2 0 0 2 2 2 0 GAF domain Sgf11_N PF18519.1 KDO34150.1 - 0.14 11.7 0.2 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain C1_2 PF03107.16 KDO34150.1 - 0.32 11.3 5.9 0.8 10.1 5.9 1.7 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 KDO34150.1 - 0.66 10.2 6.6 1.5 9.1 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PI3Ka PF00613.20 KDO34151.1 - 1.2e-45 155.2 0.5 2.6e-45 154.1 0.5 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KDO34151.1 - 7.5e-30 104.5 0.7 3.2e-16 59.9 0.2 2.8 1 1 2 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KDO34151.1 - 4e-25 88.4 0.0 7.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DnaJ PF00226.31 KDO34152.1 - 7.8e-08 32.3 0.1 1.8e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KDO34152.1 - 8.6e-06 26.2 2.3 4.7 7.8 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34152.1 - 0.0038 17.9 6.8 2e+02 3.3 0.0 6.6 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34152.1 - 0.0039 17.3 0.1 66 4.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34152.1 - 0.0067 16.7 2.4 8.4 6.8 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34152.1 - 0.057 13.5 2.7 7.6 6.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34152.1 - 0.062 13.4 8.4 14 6.1 0.1 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34152.1 - 0.083 13.1 11.0 4.9 7.4 0.1 5.3 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KDO34152.1 - 0.12 13.1 7.4 1.3 9.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34152.1 - 0.18 12.5 3.7 1.1e+02 3.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Leu_Phe_trans PF03588.14 KDO34155.1 - 7.7e-28 97.1 0.0 1.1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 KDO34155.1 - 0.07 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RasGEF PF00617.19 KDO34156.1 - 3.5e-38 131.6 2.6 4.9e-38 131.1 1.0 1.8 1 1 1 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KDO34156.1 - 2e-14 53.7 0.3 4.9e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif tRNA-synt_1g PF09334.11 KDO34157.1 - 6.6e-101 337.9 0.4 7.7e-100 334.4 0.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KDO34157.1 - 1.2e-24 86.6 1.4 1.3e-10 40.2 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KDO34157.1 - 3.6e-11 43.0 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 KDO34157.1 - 0.0023 17.0 0.0 0.0056 15.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) Peptidase_M20 PF01546.28 KDO34159.1 - 4.1e-34 118.1 0.0 5.4e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO34159.1 - 1.6e-09 37.7 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KDO34159.1 - 6.4e-06 26.0 0.0 5.3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Patatin PF01734.22 KDO34160.1 - 6.9e-11 42.7 5.0 3.1e-05 24.2 1.9 2.1 1 1 1 2 2 2 2 Patatin-like phospholipase Patatin PF01734.22 KDO34161.1 - 2.8e-14 53.8 1.3 6.1e-07 29.8 1.0 2.0 1 1 1 2 2 2 2 Patatin-like phospholipase cNMP_binding PF00027.29 KDO34162.1 - 3.3e-12 46.3 0.1 6.9e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 KDO34163.1 - 4.8e-15 55.4 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO34163.1 - 3.4e-05 23.2 12.2 0.00015 21.1 12.2 1.9 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO34164.1 - 1.8e-15 56.8 0.1 4.7e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO34164.1 - 2.5e-15 56.4 18.8 3.8e-15 55.8 18.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KDO34165.1 - 2.5e-18 66.2 10.5 4.4e-18 65.4 10.5 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO34165.1 - 5.9e-17 61.5 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4179 PF13786.6 KDO34165.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2976 PF11190.8 KDO34165.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Pkinase PF00069.25 KDO34166.1 - 7.2e-49 166.5 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34166.1 - 5.7e-48 163.4 0.0 8.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO34166.1 - 0.00013 22.3 15.1 0.0029 18.0 3.9 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO34166.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO34166.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 KDO34166.1 - 1 9.2 9.8 0.41 10.4 3.6 3.1 1 1 3 4 4 4 0 Leucine rich repeat MCM_OB PF17207.3 KDO34167.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 MCM OB domain AAA_11 PF13086.6 KDO34167.1 - 5 6.8 10.5 9.3 6.0 10.5 1.4 1 0 0 1 1 1 0 AAA domain Histone PF00125.24 KDO34168.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KDO34168.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KDO34168.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO34168.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KDO34168.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KDO34168.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KDO34169.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KDO34169.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KDO34169.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KDO34169.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KDO34169.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KDO34169.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KDO34169.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF2116 PF09889.9 KDO34170.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Bromo_MP PF01573.16 KDO34171.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Bromovirus movement protein GRIP PF01465.20 KDO34173.1 - 8.7e-17 60.8 0.3 4.9e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 GRIP domain Tup_N PF08581.10 KDO34173.1 - 0.013 15.8 33.6 0.76 10.1 3.1 7.6 5 3 2 7 7 7 0 Tup N-terminal Csm1_N PF18504.1 KDO34173.1 - 0.024 14.9 43.1 0.027 14.8 0.8 8.5 7 1 2 9 9 9 0 Csm1 N-terminal domain Ribosomal_S15 PF00312.22 KDO34173.1 - 0.98 9.7 4.5 3.4 7.9 0.5 3.3 3 0 0 3 3 3 0 Ribosomal protein S15 DUF641 PF04859.12 KDO34173.1 - 4 7.8 51.4 0.081 13.3 4.7 6.0 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 KDO34173.1 - 9 7.0 53.8 0.38 11.4 0.3 9.0 6 2 4 10 10 10 0 SlyX SAP PF02037.27 KDO34174.1 - 8.4e-13 47.7 0.7 1.8e-12 46.7 0.7 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KDO34174.1 - 7.7e-06 25.6 19.6 0.00093 19.0 4.2 3.8 1 1 2 4 4 4 3 Tho1/MOS11 C-terminal domain DUF3275 PF11679.8 KDO34174.1 - 4.2 7.3 9.1 7.3 6.5 8.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) ANAPC4_WD40 PF12894.7 KDO34175.1 - 1.9e-13 50.5 1.1 0.0075 16.6 0.0 6.5 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KDO34175.1 - 5.9e-08 32.2 11.8 0.00018 20.7 0.2 5.1 3 3 1 4 4 4 2 Coatomer WD associated region Clathrin PF00637.20 KDO34175.1 - 2.5e-06 27.4 27.7 0.043 13.7 0.2 9.4 5 2 6 11 11 11 3 Region in Clathrin and VPS WD40 PF00400.32 KDO34175.1 - 7.4e-05 23.4 1.4 5.1 8.1 0.0 5.5 6 0 0 6 6 5 1 WD domain, G-beta repeat DPPIV_N PF00930.21 KDO34175.1 - 0.0092 14.8 1.0 1 8.1 0.2 3.2 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Sec16_C PF12931.7 KDO34175.1 - 0.05 13.3 7.9 4.2 6.9 0.1 5.1 5 0 0 5 5 5 0 Sec23-binding domain of Sec16 Mistic PF11458.8 KDO34175.1 - 0.09 12.7 0.2 0.75 9.8 0.0 2.6 2 0 0 2 2 2 0 Membrane-integrating protein Mistic DZR PF12773.7 KDO34175.1 - 0.1 12.6 9.6 0.26 11.3 9.6 1.8 1 0 0 1 1 1 0 Double zinc ribbon PPR PF01535.20 KDO34175.1 - 0.18 12.1 10.1 24 5.4 0.2 6.8 8 0 0 8 8 7 0 PPR repeat zf-ribbon_3 PF13248.6 KDO34175.1 - 0.21 11.1 6.1 0.41 10.1 2.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain TPR_7 PF13176.6 KDO34175.1 - 0.35 11.0 24.6 18 5.7 1.7 10.1 11 2 0 11 11 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34175.1 - 0.37 11.0 36.3 4.6 7.6 1.5 10.8 11 1 1 12 12 11 0 Tetratricopeptide repeat PPR_2 PF13041.6 KDO34175.1 - 1.3 9.2 6.8 21 5.4 0.0 5.7 4 1 1 5 5 5 0 PPR repeat family TPR_11 PF13414.6 KDO34175.1 - 5 6.9 6.8 21 4.9 0.0 5.1 5 0 0 5 5 5 0 TPR repeat CTP_transf_1 PF01148.20 KDO34176.1 - 7.8e-39 134.0 13.7 1e-36 127.1 13.7 2.2 1 1 0 1 1 1 1 Cytidylyltransferase family DUF2975 PF11188.8 KDO34176.1 - 6.3 6.7 9.1 11 6.0 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) ACBP PF00887.19 KDO34177.1 - 4.6e-31 106.9 1.6 5.1e-31 106.7 1.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Pyridoxal_deC PF00282.19 KDO34178.1 - 1.5e-18 66.7 0.0 2.3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KDO34178.1 - 2.5e-08 33.3 0.0 5.6e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Apq12 PF12716.7 KDO34178.1 - 0.17 11.8 3.1 0.3 11.0 0.3 2.5 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis Acyl_transf_3 PF01757.22 KDO34179.1 - 1.1e-17 64.2 33.5 1.1e-17 64.2 33.5 1.8 2 1 0 2 2 2 1 Acyltransferase family DUF4131 PF13567.6 KDO34179.1 - 0.14 11.8 0.1 0.14 11.8 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1418 PF07214.12 KDO34179.1 - 0.58 10.0 6.1 7.6 6.5 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF3323 PF11796.8 KDO34180.1 - 0.071 13.0 0.7 0.37 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Catalase PF00199.19 KDO34180.1 - 0.18 10.8 0.0 0.54 9.3 0.0 1.6 2 0 0 2 2 2 0 Catalase LsmAD PF06741.13 KDO34181.1 - 1.4e-15 57.6 0.3 4.9e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 LsmAD domain Ank_2 PF12796.7 KDO34181.1 - 3.7e-07 30.6 0.1 9.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_2 PF07719.17 KDO34181.1 - 1.3e-05 24.9 6.5 0.77 10.0 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34181.1 - 2.4e-05 24.5 4.2 7.2e-05 23.0 4.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Ank_5 PF13857.6 KDO34181.1 - 0.00077 19.7 0.1 0.0074 16.6 0.0 2.6 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34181.1 - 0.0012 19.1 0.0 0.015 15.8 0.0 2.7 3 0 0 3 3 2 1 Ankyrin repeat TPR_MalT PF17874.1 KDO34181.1 - 0.0013 18.1 0.1 0.0028 17.1 0.1 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 KDO34181.1 - 0.0075 16.4 7.1 0.37 11.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_4 PF13637.6 KDO34181.1 - 0.024 15.2 0.0 0.1 13.2 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (many copies) TPR_7 PF13176.6 KDO34181.1 - 0.039 14.0 2.4 2.6 8.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34181.1 - 0.057 13.3 5.4 5.2 7.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank PF00023.30 KDO34181.1 - 0.06 13.8 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat TPR_10 PF13374.6 KDO34181.1 - 0.58 10.1 2.8 2.9 7.9 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD_2 PF13831.6 KDO34182.1 - 1.8 8.2 9.7 0.08 12.5 2.5 2.6 2 1 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KDO34182.1 - 3.8 7.7 6.8 0.16 12.1 0.7 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain PX PF00787.24 KDO34183.1 - 3.2e-24 85.1 0.2 5.1e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KDO34183.1 - 9.2e-11 41.7 1.1 1.4e-10 41.1 1.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like BAR PF03114.18 KDO34183.1 - 0.036 13.7 3.1 0.12 12.0 3.1 1.8 1 1 0 1 1 1 0 BAR domain TIR_2 PF13676.6 KDO34184.1 - 9e-20 71.4 0.0 3.8e-13 50.1 0.0 3.0 2 1 1 3 3 3 2 TIR domain SH2 PF00017.24 KDO34184.1 - 7.8e-10 38.7 0.0 2.5e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 SH2 domain AAA_16 PF13191.6 KDO34184.1 - 2.6e-06 27.9 0.0 6.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KDO34184.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Zn_Tnp_IS1595 PF12760.7 KDO34184.1 - 0.014 15.4 0.7 0.037 14.0 0.7 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KDO34184.1 - 0.028 14.3 0.2 0.081 12.9 0.2 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon NACHT PF05729.12 KDO34184.1 - 0.099 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KDO34184.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NSP11 PF06471.12 KDO34184.1 - 0.19 10.1 0.1 0.38 9.2 0.0 1.5 2 0 0 2 2 2 0 NSP11 DUF2075 PF09848.9 KDO34184.1 - 0.22 10.7 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FYVE PF01363.21 KDO34185.1 - 4e-12 46.1 11.8 8.8e-12 45.0 11.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34185.1 - 8.8e-08 32.9 0.6 2.3e-07 31.5 0.2 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KDO34185.1 - 3.6e-05 24.1 0.1 0.00012 22.4 0.1 1.9 2 0 0 2 2 2 1 GAF domain PHF5 PF03660.14 KDO34185.1 - 0.033 14.4 6.2 0.066 13.4 6.2 1.4 1 0 0 1 1 1 0 PHF5-like protein FYVE PF01363.21 KDO34186.1 - 5.9e-14 52.0 15.0 6e-14 51.9 12.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 KDO34186.1 - 0.00038 21.1 0.4 0.00038 21.1 0.4 2.3 1 1 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO34186.1 - 0.0032 17.7 7.9 0.007 16.6 7.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 KDO34186.1 - 0.019 15.3 0.1 0.043 14.2 0.1 1.6 1 0 0 1 1 1 0 GAF domain DUF4428 PF14471.6 KDO34186.1 - 0.06 13.3 2.0 0.15 12.0 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) FYVE PF01363.21 KDO34187.1 - 9.4e-13 48.1 12.9 1.8e-12 47.2 12.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34187.1 - 1.1e-09 39.0 1.0 2.1e-09 38.1 0.3 1.8 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KDO34187.1 - 3.2e-08 34.0 0.2 6.7e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KDO34187.1 - 4e-05 23.9 0.1 8.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 GAF domain YdjC PF04794.12 KDO34187.1 - 0.021 14.8 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 YdjC-like protein FYVE_2 PF02318.16 KDO34187.1 - 0.037 14.3 8.4 0.072 13.3 8.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger dUTPase PF00692.19 KDO34188.1 - 9.3e-45 151.5 0.0 1.2e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF3037 PF11236.8 KDO34188.1 - 0.13 12.7 0.4 0.39 11.1 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Sugar_tr PF00083.24 KDO34189.1 - 2e-30 106.1 24.9 1.7e-23 83.2 4.9 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KDO34189.1 - 4.5e-23 81.7 56.0 7.3e-22 77.8 32.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KDO34190.1 - 1.3e-07 32.2 11.2 2.1 9.4 0.7 6.6 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34190.1 - 0.00047 20.4 0.1 2 8.8 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KDO34191.1 - 1.7e-43 148.9 0.0 4.6e-43 147.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34191.1 - 3.9e-30 105.0 0.0 6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34191.1 - 2.4e-05 23.8 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO34191.1 - 0.0016 17.3 0.1 0.0042 15.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase zf-C3HC4 PF00097.25 KDO34191.1 - 0.0052 16.6 5.7 0.013 15.4 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) APH PF01636.23 KDO34191.1 - 0.062 13.2 1.1 0.069 13.1 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_2 PF13923.6 KDO34191.1 - 0.077 12.9 5.8 0.3 11.0 5.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KDO34191.1 - 0.084 12.8 5.7 0.21 11.5 5.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO34191.1 - 0.2 11.7 1.5 0.41 10.7 0.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KDO34191.1 - 0.48 10.3 4.3 1.8 8.5 4.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO34191.1 - 0.49 10.8 8.8 0.087 13.2 4.6 2.0 2 0 0 2 2 1 0 Ring finger domain zf-RING_5 PF14634.6 KDO34191.1 - 0.57 10.2 5.4 1.3 9.1 5.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KDO34191.1 - 5.7 7.2 6.2 13 6.1 6.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING AA_permease_2 PF13520.6 KDO34192.1 - 4e-40 137.9 36.5 4e-40 137.9 36.5 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KDO34192.1 - 3.8e-25 88.4 36.7 3.8e-25 88.4 36.7 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KDO34192.1 - 4e-12 46.0 3.6 4e-12 46.0 3.6 3.6 4 0 0 4 4 4 1 C-terminus of AA_permease Voltage_CLC PF00654.20 KDO34193.1 - 8.8e-67 225.8 27.8 1.6e-66 225.0 27.8 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KDO34193.1 - 0.00036 20.9 0.4 1 9.8 0.1 2.5 2 0 0 2 2 2 2 CBS domain F5_F8_type_C PF00754.25 KDO34194.1 - 2.8 8.1 8.1 0.25 11.4 2.7 1.8 2 0 0 2 2 2 0 F5/8 type C domain WD40 PF00400.32 KDO34195.1 - 0.042 14.7 3.0 4.1 8.4 0.0 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34195.1 - 0.073 13.4 0.0 12 6.3 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KDO34195.1 - 0.1 10.9 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Hamartin PF04388.12 KDO34195.1 - 0.32 9.6 25.6 0.48 9.0 25.6 1.2 1 0 0 1 1 1 0 Hamartin protein GMP_PDE_delta PF05351.11 KDO34196.1 - 3.2e-33 115.0 0.0 5.7e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 GMP-PDE, delta subunit DUF1357 PF07094.11 KDO34196.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) LRR_6 PF13516.6 KDO34197.1 - 1.3e-15 56.1 18.5 0.0001 22.1 0.3 6.5 6 0 0 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.33 KDO34197.1 - 5.4e-05 23.2 0.8 8.1 7.4 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 KDO34197.1 - 0.17 12.4 6.3 0.35 11.4 0.3 3.5 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) FlaC_arch PF05377.11 KDO34197.1 - 0.79 10.2 10.6 53 4.3 0.3 5.1 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KDO34197.1 - 1.3 9.2 17.7 6 7.1 0.2 4.3 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Exo_endo_phos PF03372.23 KDO34198.1 - 8.9e-07 28.7 0.1 2.1e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M20 PF01546.28 KDO34199.1 - 2.8e-16 59.8 0.0 1.1e-13 51.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 WD40 PF00400.32 KDO34199.1 - 7.8e-14 51.9 6.6 2.9e-06 27.9 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.14 KDO34199.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.11 KDO34199.1 - 0.03 13.1 0.5 1.9 7.2 0.2 2.8 1 1 1 2 2 2 0 Nup133 N terminal like WD40 PF00400.32 KDO34200.1 - 9.5e-30 102.2 21.6 9.4e-08 32.6 0.2 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Peptidase_M20 PF01546.28 KDO34200.1 - 6.9e-06 25.9 0.0 0.00055 19.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KDO34200.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 KDO34200.1 - 0.0067 15.1 14.8 0.75 8.4 1.4 5.4 3 1 1 5 5 5 2 Nucleoporin Nup120/160 Pkinase PF00069.25 KDO34201.1 - 5.2e-48 163.7 0.0 7.2e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34201.1 - 9.5e-46 156.2 0.0 1.3e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO34201.1 - 3.5e-05 22.8 0.0 5.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KDO34201.1 - 0.018 14.0 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO34201.1 - 0.035 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_CR2 PF02439.15 KDO34201.1 - 0.056 13.2 0.5 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3767 PF12597.8 KDO34201.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Kinase-like PF14531.6 KDO34201.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EphA2_TM PF14575.6 KDO34201.1 - 0.14 13.0 0.2 0.6 11.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KDO34201.1 - 0.16 11.4 2.8 0.39 10.2 2.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Stevor PF17410.2 KDO34201.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Pkinase PF00069.25 KDO34202.1 - 8e-33 113.9 0.0 1.5e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34202.1 - 2.4e-31 109.0 0.0 4.6e-18 65.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase MLANA PF14991.6 KDO34202.1 - 0.017 15.4 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A DUF202 PF02656.15 KDO34202.1 - 0.04 14.3 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF202) AstA PF04958.12 KDO34202.1 - 0.098 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Hum_adeno_E3A PF05393.11 KDO34202.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein PHBC_N PF12551.8 KDO34202.1 - 0.13 12.1 0.5 0.31 10.8 0.5 1.6 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Adeno_E3_CR2 PF02439.15 KDO34202.1 - 0.43 10.4 5.5 0.9 9.4 5.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BK_channel_a PF03493.18 KDO34203.1 - 1.4e-24 86.1 0.1 1.8e-23 82.5 0.1 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO34203.1 - 2.5e-12 46.6 0.2 2.5e-12 46.6 0.2 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KDO34203.1 - 2.1e-11 43.5 10.7 4.9e-11 42.3 10.7 1.6 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO34203.1 - 0.00041 20.6 0.0 0.036 14.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain CBP_BcsG PF11658.8 KDO34203.1 - 0.05 12.0 0.0 0.12 10.7 0.0 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Lig_chan PF00060.26 KDO34203.1 - 0.13 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel Phytochelatin PF05023.14 KDO34204.1 - 5.8e-13 48.5 0.0 2.7e-10 39.8 0.0 2.7 1 1 1 2 2 2 2 Phytochelatin synthase Amidase PF01425.21 KDO34205.1 - 9.9e-55 186.3 0.2 1.3e-52 179.3 0.1 2.9 1 1 0 2 2 2 2 Amidase FHA PF00498.26 KDO34206.1 - 3e-08 33.9 0.1 5.6e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain CHAT PF12770.7 KDO34206.1 - 5.6e-06 26.0 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 KDO34206.1 - 7.9e-06 25.9 0.5 0.0014 18.6 0.5 2.4 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KDO34206.1 - 0.00039 20.9 0.0 0.00077 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KDO34206.1 - 0.008 16.6 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KDO34206.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KDO34206.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KDO34206.1 - 0.077 12.2 0.0 1.3 8.2 0.0 2.2 1 1 1 2 2 2 0 NB-ARC domain TsaE PF02367.17 KDO34206.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KDO34206.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TAL_effector PF03377.13 KDO34206.1 - 0.17 12.3 0.0 0.54 10.6 0.0 1.9 1 0 0 1 1 1 0 TAL effector repeat RNA_helicase PF00910.22 KDO34206.1 - 0.2 12.1 0.0 0.95 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Abhydrolase_1 PF00561.20 KDO34207.1 - 3.9e-26 92.2 0.6 1.2e-24 87.4 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO34207.1 - 1e-21 78.6 0.0 1.2e-21 78.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO34207.1 - 5.6e-19 68.3 0.1 7.1e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KDO34207.1 - 0.00023 20.8 0.8 0.03 13.9 0.1 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 KDO34207.1 - 0.0005 20.0 0.1 0.00095 19.1 0.1 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_8 PF06259.12 KDO34207.1 - 0.0075 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 KDO34207.1 - 0.012 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 KDO34207.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 KDO34207.1 - 0.051 13.3 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KDO34207.1 - 0.071 12.9 0.0 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Kelch_1 PF01344.25 KDO34208.1 - 2.9e-40 135.6 7.4 2.5e-09 36.6 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KDO34208.1 - 5.8e-39 131.9 19.0 5.8e-10 39.0 0.3 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO34208.1 - 3.3e-38 129.1 4.6 1.1e-06 28.4 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KDO34208.1 - 9.1e-35 118.3 21.0 8.2e-07 29.2 0.2 6.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO34208.1 - 1e-33 114.5 7.3 6.8e-05 23.0 0.2 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KDO34208.1 - 2.5e-33 112.8 13.0 2.3e-07 30.5 0.1 6.2 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 KDO34208.1 - 1.4e-27 96.1 1.5 6.5e-26 90.7 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KDO34208.1 - 0.0022 18.1 0.4 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch MAPEG PF01124.18 KDO34209.1 - 2.3e-19 69.6 2.0 2.7e-19 69.4 2.0 1.0 1 0 0 1 1 1 1 MAPEG family SLC35F PF06027.12 KDO34210.1 - 8.4e-57 193.0 19.3 9.7e-57 192.7 19.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KDO34210.1 - 3.6e-08 32.7 3.3 3.6e-08 32.7 3.3 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KDO34210.1 - 0.00089 19.4 10.1 0.00089 19.4 10.1 2.5 2 0 0 2 2 2 1 EamA-like transporter family DoxX_2 PF13564.6 KDO34210.1 - 0.012 15.7 4.1 0.057 13.5 4.1 2.3 1 0 0 1 1 1 0 DoxX-like family CTK3 PF12243.8 KDO34211.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Lung_7-TM_R PF06814.13 KDO34213.1 - 0.28 10.4 13.2 2.5 7.3 13.2 2.2 1 1 0 1 1 1 0 Lung seven transmembrane receptor Tropomyosin_1 PF12718.7 KDO34214.1 - 0.01 16.0 2.6 0.75 9.9 0.0 2.0 1 1 1 2 2 2 0 Tropomyosin like ETRAMP PF09716.10 KDO34214.1 - 0.32 11.1 1.8 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ATG11 PF10377.9 KDO34215.1 - 4.3e-19 68.9 0.0 9.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.12 KDO34215.1 - 2.5e-15 56.5 10.2 1.1e-10 41.3 0.6 3.7 2 1 2 4 4 4 2 Autophagy protein Apg17 KLRAQ PF10205.9 KDO34215.1 - 0.0034 17.6 0.8 0.055 13.7 0.0 2.8 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein ubiquitin PF00240.23 KDO34215.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family AKNA PF12443.8 KDO34215.1 - 0.025 15.2 0.0 11 6.8 0.1 3.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor TBK1_ULD PF18396.1 KDO34215.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RNase_E_G PF10150.9 KDO34215.1 - 0.062 12.7 0.4 0.14 11.6 0.4 1.5 1 0 0 1 1 1 0 Ribonuclease E/G family Gemin7 PF11095.8 KDO34215.1 - 0.062 13.2 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) TSC22 PF01166.18 KDO34215.1 - 0.15 12.4 0.3 0.69 10.3 0.1 2.3 2 0 0 2 2 1 0 TSC-22/dip/bun family Atg14 PF10186.9 KDO34215.1 - 0.23 10.5 6.1 0.45 9.5 0.0 3.4 2 2 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 BMFP PF04380.13 KDO34215.1 - 0.59 10.7 5.5 36 4.9 0.1 4.5 4 0 0 4 4 4 0 Membrane fusogenic activity Lzipper-MIP1 PF14389.6 KDO34215.1 - 2.3 8.6 6.1 10 6.5 0.0 4.1 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 COG5 PF10392.9 KDO34215.1 - 5.1 7.3 8.1 1.2 9.4 0.2 3.6 3 1 1 4 4 4 0 Golgi transport complex subunit 5 ABC_tran_CTD PF16326.5 KDO34215.1 - 6.2 7.1 17.0 0.42 10.9 0.2 5.3 5 1 1 6 6 6 0 ABC transporter C-terminal domain Abhydrolase_3 PF07859.13 KDO34216.1 - 4.8e-21 75.6 1.9 8.3e-21 74.8 1.9 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KDO34216.1 - 4.9e-16 58.7 0.1 9.2e-15 54.5 0.0 2.5 2 1 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KDO34216.1 - 1.9e-06 27.0 0.3 0.0059 15.5 0.1 2.3 1 1 1 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KDO34216.1 - 0.0023 18.6 8.1 0.0023 18.6 8.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KDO34216.1 - 0.0043 16.4 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 KDO34216.1 - 0.028 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase rve_3 PF13683.6 KDO34216.1 - 0.087 12.6 0.0 5.2 6.9 0.1 2.5 2 0 0 2 2 2 0 Integrase core domain WD40 PF00400.32 KDO34217.1 - 3.1e-29 100.6 17.1 9.6e-07 29.4 1.0 8.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34217.1 - 8.6e-23 80.5 0.1 0.00019 21.7 0.0 6.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ricin_B_lectin PF00652.22 KDO34217.1 - 7e-20 71.6 3.7 2.4e-10 40.7 0.0 3.6 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain Cellulase PF00150.18 KDO34217.1 - 1.4e-14 54.2 0.4 2.7e-14 53.3 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RicinB_lectin_2 PF14200.6 KDO34217.1 - 2.3e-12 47.4 5.8 2.2e-07 31.5 0.0 4.5 4 1 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.16 KDO34217.1 - 2e-07 29.9 0.5 0.004 15.8 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KDO34217.1 - 1.7e-05 24.0 3.8 0.63 8.9 0.0 4.7 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 KDO34217.1 - 0.00012 21.7 0.1 0.42 10.2 0.0 2.9 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain eIF2A PF08662.11 KDO34217.1 - 0.00028 20.8 0.0 0.85 9.5 0.0 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KDO34217.1 - 0.0012 17.3 0.0 0.049 11.9 0.0 2.8 2 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 KDO34217.1 - 0.0025 16.9 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Nbas_N PF15492.6 KDO34217.1 - 0.0071 15.7 0.0 0.1 11.9 0.0 2.7 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KDO34217.1 - 0.012 15.0 0.0 5.9 6.1 0.0 3.6 3 1 1 4 4 4 0 WD40-like domain Nup160 PF11715.8 KDO34217.1 - 0.017 13.8 0.0 0.27 9.8 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ PF01011.21 KDO34217.1 - 0.018 14.9 0.0 7.6 6.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Lactonase PF10282.9 KDO34217.1 - 0.074 12.3 0.0 0.44 9.8 0.0 1.9 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ET PF01684.16 KDO34217.1 - 0.18 12.2 1.5 15 6.0 0.1 2.6 2 0 0 2 2 2 0 ET module Lon_C PF05362.13 KDO34218.1 - 2.1e-56 190.7 0.1 3.8e-56 189.9 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KDO34218.1 - 6.1e-21 75.2 0.0 1.2e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KDO34218.1 - 5.2e-12 46.1 0.0 8.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KDO34218.1 - 7.7e-11 42.2 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO34218.1 - 2.9e-07 30.8 0.0 5.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KDO34218.1 - 7.6e-05 22.5 0.1 0.00021 21.1 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KDO34218.1 - 0.00015 22.0 0.9 0.024 14.9 0.9 2.6 1 1 0 1 1 1 1 AAA domain ChlI PF13541.6 KDO34218.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 KDO34218.1 - 0.0008 18.4 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain NACHT PF05729.12 KDO34218.1 - 0.0013 18.7 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KDO34218.1 - 0.0014 19.0 6.5 0.0039 17.6 0.1 3.1 2 2 0 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 KDO34218.1 - 0.0046 16.9 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 1 NTPase RuvB_N PF05496.12 KDO34218.1 - 0.0059 16.4 0.2 0.027 14.2 0.2 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KDO34218.1 - 0.023 14.4 0.2 0.058 13.1 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KDO34218.1 - 0.026 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KDO34218.1 - 0.027 14.4 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KDO34218.1 - 0.029 14.9 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KDO34218.1 - 0.041 14.0 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KDO34218.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KDO34218.1 - 0.051 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KDO34218.1 - 0.059 13.4 0.2 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KDO34218.1 - 0.1 11.8 0.0 0.35 10.0 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 KDO34218.1 - 0.13 11.6 0.3 0.28 10.5 0.1 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KDO34218.1 - 0.15 11.7 4.8 0.11 12.1 0.4 2.9 3 1 1 4 4 3 0 AAA domain Roc PF08477.13 KDO34218.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase V-ATPase_C PF03223.15 KDO34219.1 - 1.7e-113 379.8 0.3 2.1e-113 379.5 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C COG2 PF06148.11 KDO34219.1 - 0.073 13.2 0.4 7.2 6.7 0.1 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mst1_SARAH PF11629.8 KDO34219.1 - 0.67 10.1 3.2 1 9.5 0.4 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 RRM_1 PF00076.22 KDO34220.1 - 8.8e-77 252.9 4.7 1.1e-18 66.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO34220.1 - 1.1e-11 44.4 0.0 0.036 13.7 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO34220.1 - 1.8e-07 30.9 0.2 0.048 13.5 0.0 4.6 6 0 0 6 6 6 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KDO34220.1 - 0.0018 18.4 0.1 27 5.0 0.0 4.8 5 0 0 5 5 5 0 RNA recognition motif SseB_C PF14581.6 KDO34220.1 - 0.037 14.1 0.2 0.23 11.6 0.0 2.5 3 0 0 3 3 3 0 SseB protein C-terminal domain BUD22 PF09073.10 KDO34220.1 - 0.044 13.1 24.1 0.12 11.7 24.1 1.7 1 0 0 1 1 1 0 BUD22 Nup35_RRM_2 PF14605.6 KDO34220.1 - 0.079 13.0 3.0 28 4.8 0.1 4.3 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif DUF2098 PF09871.9 KDO34220.1 - 0.21 11.9 0.1 0.21 11.9 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) PHM7_cyt PF14703.6 KDO34220.1 - 0.31 11.2 7.8 5.6 7.2 0.5 5.3 3 3 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter AATF-Che1 PF13339.6 KDO34220.1 - 7 7.3 10.9 50 4.6 0.1 3.6 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Sld5 PF05916.11 KDO34223.1 - 4.4e-09 36.8 0.0 7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein TFIIF_alpha PF05793.12 KDO34224.1 - 1.2e-22 80.2 38.4 2.5e-18 66.0 38.4 2.5 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2868 PF11067.8 KDO34224.1 - 0.15 11.5 0.2 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF4660 PF15559.6 KDO34225.1 - 0.00041 20.6 0.2 0.00041 20.6 0.2 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4660) DUF3246 PF11596.8 KDO34225.1 - 0.4 10.1 3.5 0.47 9.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) ELMO_CED12 PF04727.13 KDO34226.1 - 1.5e-32 113.1 0.0 3e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family RhoGAP PF00620.27 KDO34226.1 - 6e-19 68.4 0.2 2.3e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain RUN PF02759.19 KDO34226.1 - 2.9e-13 49.9 0.7 1.7e-12 47.5 0.1 2.5 3 0 0 3 3 3 1 RUN domain Nuc_rec_co-act PF08815.10 KDO34226.1 - 0.042 13.7 0.2 11 5.9 0.6 2.7 2 0 0 2 2 2 0 Nuclear receptor coactivator Enkurin PF13864.6 KDO34226.1 - 1.2 9.6 4.4 0.64 10.5 0.3 2.5 2 0 0 2 2 2 0 Calmodulin-binding Golgin_A5 PF09787.9 KDO34228.1 - 6.6e-13 48.8 40.6 2.3e-10 40.4 22.3 3.6 1 1 2 3 3 3 2 Golgin subfamily A member 5 Leu_zip PF15294.6 KDO34228.1 - 5e-05 22.9 7.9 5e-05 22.9 7.9 3.3 1 1 3 4 4 4 1 Leucine zipper Hrs_helical PF12210.8 KDO34228.1 - 0.088 13.4 0.6 0.088 13.4 0.6 5.0 3 2 2 5 5 5 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Fez1 PF06818.15 KDO34228.1 - 0.57 10.6 38.3 0.26 11.7 11.2 3.1 1 1 1 2 2 2 0 Fez1 Shugoshin_N PF07558.11 KDO34228.1 - 2.1 8.3 9.5 1.8 8.5 0.1 3.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Tetraspanin PF00335.20 KDO34229.1 - 5.1e-08 32.9 22.2 1e-07 31.9 22.2 1.5 1 1 0 1 1 1 1 Tetraspanin family CDP-OH_P_transf PF01066.21 KDO34230.1 - 1.9e-15 57.4 0.4 1.9e-15 57.4 0.4 4.0 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Mito_carr PF00153.27 KDO34231.1 - 1.9e-57 191.1 0.6 3.3e-20 71.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.7 KDO34231.1 - 0.2 12.2 0.1 27 5.4 0.0 2.3 2 0 0 2 2 2 0 YtxH-like protein Snf7 PF03357.21 KDO34232.1 - 5.7e-30 104.2 24.1 6.8e-30 103.9 24.1 1.1 1 0 0 1 1 1 1 Snf7 Arm-DNA-bind_3 PF13356.6 KDO34232.1 - 0.025 14.9 0.3 0.073 13.5 0.3 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain RGS-like PF09128.11 KDO34232.1 - 0.96 9.1 11.6 0.08 12.7 5.4 1.9 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain PBP1_TM PF14812.6 KDO34233.1 - 0.026 14.9 3.9 0.049 14.0 1.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Crust_neurohorm PF01147.17 KDO34233.1 - 0.066 13.0 2.3 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family NOA36 PF06524.12 KDO34233.1 - 0.93 8.8 4.1 2.1 7.6 4.1 1.5 1 0 0 1 1 1 0 NOA36 protein DUF724 PF05266.14 KDO34236.1 - 0.0018 18.1 1.4 0.0018 18.1 1.4 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF724) BAR PF03114.18 KDO34236.1 - 0.067 12.8 5.7 0.059 13.0 0.9 2.3 2 0 0 2 2 2 0 BAR domain Atg14 PF10186.9 KDO34236.1 - 0.17 11.0 19.6 0.23 10.5 4.0 3.2 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 EF-hand_7 PF13499.6 KDO34236.1 - 0.18 12.3 0.0 0.55 10.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair ATG16 PF08614.11 KDO34236.1 - 0.64 10.2 31.5 0.023 14.9 7.2 4.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KDO34236.1 - 2.7 8.1 10.8 1.4 9.0 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KDO34236.1 - 4.5 7.8 18.1 0.26 11.8 2.2 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region Phage_Mu_F PF04233.14 KDO34236.1 - 6.2 7.6 7.1 1.4 9.7 2.4 2.3 2 0 0 2 2 2 0 Phage Mu protein F like protein Mtc PF03820.17 KDO34239.1 - 2.3e-104 348.8 0.0 2.6e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.32 KDO34240.1 - 1.6e-54 180.6 20.2 8.9e-10 39.0 0.5 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34240.1 - 1.3e-15 57.4 0.0 0.0044 17.3 0.0 5.2 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KDO34240.1 - 2e-06 27.0 4.2 0.00053 19.1 2.6 3.0 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO34240.1 - 6.2e-06 25.1 0.6 0.27 9.8 0.0 4.1 1 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KDO34240.1 - 0.00076 18.3 0.0 0.51 9.0 0.0 2.8 1 1 1 3 3 3 2 Nup133 N terminal like ELMO_CED12 PF04727.13 KDO34241.1 - 1.8e-41 142.2 1.8 2.1e-41 141.9 0.1 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family AAA_34 PF13872.6 KDO34242.1 - 1.1e-100 336.4 0.1 1.6e-100 335.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KDO34242.1 - 9.7e-84 281.2 0.4 2.8e-83 279.7 0.2 1.8 1 1 1 2 2 2 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KDO34242.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KDO34242.1 - 0.058 13.7 0.1 0.22 11.9 0.1 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Cript PF10235.9 KDO34243.1 - 4.7e-30 104.0 4.7 4.7e-30 104.0 4.7 1.3 2 0 0 2 2 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 KDO34243.1 - 0.004 17.5 11.7 0.0056 17.0 8.5 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_15 PF17032.5 KDO34243.1 - 0.011 16.5 8.5 0.022 15.5 5.1 2.4 2 1 0 2 2 2 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 KDO34243.1 - 0.02 14.9 6.7 0.049 13.6 2.8 2.1 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 KDO34243.1 - 0.025 14.6 12.3 0.2 11.7 8.0 2.5 1 1 1 2 2 2 0 Double zinc ribbon DUF3638 PF12340.8 KDO34243.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) PHF5 PF03660.14 KDO34243.1 - 0.17 12.1 9.0 0.078 13.2 5.8 2.1 2 1 0 2 2 2 0 PHF5-like protein Gin PF10764.9 KDO34243.1 - 0.29 11.1 8.1 4.9 7.2 0.1 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DUF1272 PF06906.11 KDO34243.1 - 0.3 11.2 7.3 0.17 12.0 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-Di19 PF05605.12 KDO34243.1 - 0.34 11.2 9.5 11 6.4 4.7 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.12 KDO34243.1 - 0.53 9.8 7.1 12 5.5 0.1 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 KDO34243.1 - 0.65 9.8 11.0 7.4 6.4 2.9 3.4 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 KDO34243.1 - 1.3 8.9 10.5 1.5 8.8 3.7 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KDO34243.1 - 3.9 7.9 11.6 16 5.9 7.6 2.7 2 1 1 3 3 3 0 C1 domain Pkinase PF00069.25 KDO34245.1 - 1e-28 100.4 0.0 1.4e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34245.1 - 9.9e-17 61.1 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO34245.1 - 2.6e-08 33.1 0.0 3.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KDO34245.1 - 0.0018 17.3 0.2 0.0029 16.7 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KDO34245.1 - 0.0062 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Loricrin PF15847.5 KDO34245.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Major keratinocyte cell envelope protein VPS9 PF02204.18 KDO34246.1 - 1.2e-08 35.1 0.0 2.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.25 KDO34247.1 - 3.8e-59 200.2 0.0 4.5e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34247.1 - 1.5e-40 139.1 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34247.1 - 9.7e-05 21.8 0.0 0.00051 19.5 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO34247.1 - 0.00061 18.7 0.0 0.00083 18.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase BRO1 PF03097.18 KDO34248.1 - 3.1e-104 348.9 2.9 3.1e-104 348.9 2.9 1.8 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KDO34248.1 - 1.6e-43 149.1 3.6 1.6e-43 149.1 3.6 2.3 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4122 PF13498.6 KDO34248.1 - 0.19 11.4 0.4 0.45 10.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) PCI PF01399.27 KDO34249.1 - 1e-13 51.7 0.0 1.7e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain RasGEF PF00617.19 KDO34249.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RasGEF domain zf-MIZ PF02891.20 KDO34250.1 - 3e-17 62.1 2.0 3e-17 62.1 2.0 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.27 KDO34250.1 - 3.5e-07 29.8 0.0 7.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain PINIT PF14324.6 KDO34250.1 - 5.1e-05 23.7 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 PINIT domain C1_1 PF00130.22 KDO34250.1 - 0.0084 16.0 3.3 0.0084 16.0 3.3 3.2 2 2 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.8 KDO34250.1 - 0.034 14.0 0.3 0.081 12.8 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KDO34250.1 - 0.11 12.4 23.0 0.042 13.7 13.9 2.4 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 KDO34250.1 - 0.51 10.6 12.4 0.14 12.4 6.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.6 KDO34250.1 - 0.55 9.8 14.4 0.07 12.7 8.5 2.3 2 0 0 2 2 2 0 PHD-finger DUF3449 PF11931.8 KDO34251.1 - 5.8e-76 254.4 1.4 5.1e-75 251.3 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KDO34251.1 - 8.1e-27 93.6 1.7 1.4e-26 92.8 0.5 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KDO34251.1 - 4.4e-11 42.5 4.1 4.6e-10 39.2 1.1 2.7 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KDO34251.1 - 5.1e-09 36.2 5.7 2e-08 34.3 1.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KDO34251.1 - 8.6e-09 35.5 1.6 8.6e-09 35.5 1.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KDO34251.1 - 0.00017 21.9 0.8 0.0058 16.9 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) MapZ_EC1 PF18041.1 KDO34251.1 - 0.0084 16.3 0.9 0.028 14.7 0.0 2.3 2 0 0 2 2 2 1 MapZ extracellular domain 1 zf-C2H2_4 PF13894.6 KDO34251.1 - 0.065 14.1 3.0 7.6 7.7 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Vps39_2 PF10367.9 KDO34251.1 - 0.097 13.1 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-DBF PF07535.12 KDO34251.1 - 0.27 11.4 5.5 0.73 10.0 0.3 2.9 2 0 0 2 2 2 0 DBF zinc finger DUF2175 PF09943.9 KDO34251.1 - 0.93 9.8 5.1 23 5.4 1.3 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3134 PF11332.8 KDO34251.1 - 0.93 9.9 0.0 0.93 9.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) PIG-F PF06699.11 KDO34252.1 - 1.5e-30 106.7 8.5 1.7e-30 106.5 8.5 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F VWA_3 PF13768.6 KDO34252.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4389 PF14333.6 KDO34252.1 - 1.4 8.9 7.5 0.23 11.4 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4389) DJ-1_PfpI PF01965.24 KDO34253.1 - 1.7e-43 148.3 0.1 1.9e-43 148.1 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Ras PF00071.22 KDO34254.1 - 3.7e-53 179.4 0.0 4.3e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO34254.1 - 1.3e-28 99.6 0.1 2.4e-28 98.8 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO34254.1 - 7.8e-11 41.7 0.0 9.5e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KDO34254.1 - 4.3e-05 23.6 0.0 8.5e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO34254.1 - 0.00032 20.6 0.0 0.75 9.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KDO34254.1 - 0.00072 19.1 0.0 0.012 15.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KDO34254.1 - 0.011 15.5 0.1 0.022 14.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KDO34254.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KDO34254.1 - 0.13 12.0 0.1 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain BCDHK_Adom3 PF10436.9 KDO34255.1 - 1e-55 188.0 0.0 1.4e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KDO34255.1 - 6.9e-13 49.1 0.0 3e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KDO34255.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1640 PF07798.11 KDO34256.1 - 0.0017 18.5 6.0 0.11 12.5 2.2 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KDO34256.1 - 0.038 14.0 11.6 2.5 8.2 0.6 4.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KDO34256.1 - 0.061 13.8 10.8 5.8 7.3 0.2 3.6 3 1 1 4 4 4 0 Fez1 DUF16 PF01519.16 KDO34256.1 - 0.23 12.0 1.4 15 6.1 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function DUF16 ATG16 PF08614.11 KDO34256.1 - 0.25 11.6 9.6 0.27 11.4 4.9 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.6 KDO34256.1 - 0.91 10.0 7.5 30 5.1 0.2 4.9 4 1 0 5 5 5 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 KDO34256.1 - 1.5 9.4 4.3 4.8 7.8 0.7 3.4 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Med11 PF10280.9 KDO34256.1 - 1.5 9.3 5.0 0.64 10.5 0.6 2.6 4 1 0 4 4 4 0 Mediator complex protein SesA PF17107.5 KDO34256.1 - 2.7 8.2 5.6 3.7 7.8 0.0 3.8 3 1 2 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF724 PF05266.14 KDO34256.1 - 5.8 6.7 9.6 9.4 6.0 0.4 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF724) DUF641 PF04859.12 KDO34256.1 - 6.1 7.2 6.5 9.4 6.6 1.3 3.5 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) DUF2730 PF10805.8 KDO34256.1 - 7 6.8 5.7 21 5.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) RPN7 PF10602.9 KDO34257.1 - 3.8e-35 121.2 0.2 7.1e-33 113.7 0.2 2.5 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KDO34257.1 - 7.9e-17 61.7 0.1 2.4e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 PCI domain HTH_Crp_2 PF13545.6 KDO34257.1 - 0.0061 16.5 0.0 0.037 14.0 0.0 2.2 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain TPR_2 PF07719.17 KDO34257.1 - 0.011 15.8 0.0 0.042 14.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34257.1 - 0.021 15.1 0.7 0.2 12.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO34259.1 - 7.1e-28 97.7 0.1 2.1e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34259.1 - 3e-17 62.8 0.0 7.3e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO34259.1 - 3.2e-09 36.1 0.0 3.2e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KDO34259.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KDO34259.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cas_Csy2 PF09614.10 KDO34259.1 - 0.088 12.1 0.5 0.14 11.5 0.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Activator_LAG-3 PF11498.8 KDO34259.1 - 1.2 8.0 21.0 1.8 7.5 21.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AICARFT_IMPCHas PF01808.18 KDO34260.1 - 2.3e-83 280.1 0.2 2.9e-83 279.7 0.2 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KDO34260.1 - 2.4e-26 91.8 0.0 5.6e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Aminotran_3 PF00202.21 KDO34261.1 - 4.6e-120 401.0 0.0 5.5e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Bax1-I PF01027.20 KDO34262.1 - 2.3e-32 112.5 23.7 2.8e-32 112.2 23.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 UL41A PF17591.2 KDO34262.1 - 3.4 7.8 5.4 1.2 9.3 0.4 2.5 1 1 1 2 2 2 0 Herpesvirus UL41A EF-hand_1 PF00036.32 KDO34263.1 - 1e-11 43.5 0.8 9.6e-05 21.7 0.1 3.0 2 0 0 2 2 2 2 EF hand LRR_6 PF13516.6 KDO34263.1 - 2.7e-10 39.4 29.3 0.052 13.6 0.0 7.7 7 0 0 7 7 7 6 Leucine Rich repeat EF-hand_7 PF13499.6 KDO34263.1 - 3.8e-09 36.9 0.0 1e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO34263.1 - 3e-08 32.9 0.3 0.00089 19.0 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO34263.1 - 4.9e-08 32.1 1.4 0.00053 19.4 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO34263.1 - 4.3e-06 26.5 0.1 2.1e-05 24.3 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain pair LRR_4 PF12799.7 KDO34263.1 - 0.011 16.2 18.3 1.7 9.2 1.8 5.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO34263.1 - 0.013 15.9 6.7 31 5.7 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat SPARC_Ca_bdg PF10591.9 KDO34263.1 - 0.071 13.4 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_8 PF13855.6 KDO34263.1 - 0.43 10.4 16.9 47 3.9 7.0 5.4 4 1 1 5 5 5 0 Leucine rich repeat AGO_N PF18236.1 KDO34264.1 - 0.077 13.2 0.2 0.16 12.2 0.1 1.5 2 0 0 2 2 2 0 Argonaute N domain Sulfotransfer_3 PF13469.6 KDO34266.1 - 1.8e-28 100.4 0.1 3.4e-28 99.5 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KDO34266.1 - 0.00052 19.6 0.0 0.0036 16.8 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain PCNA_C PF02747.15 KDO34267.1 - 1.2e-53 180.7 0.1 3.3e-53 179.3 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KDO34267.1 - 2.7e-49 166.1 0.4 4.9e-49 165.3 0.4 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KDO34267.1 - 3.4e-06 26.7 0.0 4.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KDO34267.1 - 9.1e-06 24.9 0.0 2.4e-05 23.6 0.0 1.4 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 CCD48 PF15799.5 KDO34267.1 - 0.013 13.9 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DHHC PF01529.20 KDO34268.1 - 3e-35 121.2 8.3 3e-35 121.2 8.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Aa_trans PF01490.18 KDO34269.1 - 5.5e-65 219.7 31.5 6.4e-65 219.4 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH-u_ox-rdase PF10785.9 KDO34269.1 - 0.18 12.5 1.9 0.45 11.2 0.0 2.7 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit YrhC PF14143.6 KDO34269.1 - 0.64 10.2 6.5 0.52 10.4 0.6 3.5 3 0 0 3 3 3 0 YrhC-like protein Ribosomal_S25 PF03297.15 KDO34270.1 - 1e-38 131.6 8.7 1.1e-38 131.4 8.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DprA_WH PF17782.1 KDO34270.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 DprA winged helix domain Mitoc_mL59 PF18126.1 KDO34270.1 - 0.35 11.2 6.7 0.46 10.8 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Peptidase_M24 PF00557.24 KDO34271.1 - 3.4e-09 36.7 0.1 5.9e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KDO34271.1 - 0.001 19.7 0.1 0.009 16.7 0.0 2.5 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain UFD1 PF03152.14 KDO34272.1 - 1.3e-40 138.7 0.0 1.8e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf_UBZ PF18439.1 KDO34272.1 - 0.018 14.6 21.4 0.22 11.1 0.2 5.4 4 1 1 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-RING_7 PF02591.15 KDO34272.1 - 0.084 13.1 4.7 4.6 7.5 0.0 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain Sec16_C PF12931.7 KDO34274.1 - 8.6e-09 35.5 1.0 7.4e-08 32.4 1.0 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KDO34274.1 - 3.2e-07 30.9 6.5 2.6 9.1 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat NTP_transferase PF00483.23 KDO34275.1 - 3.5e-47 161.1 0.0 4.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KDO34275.1 - 1.2e-10 40.7 6.1 9.6e-07 28.3 1.3 3.0 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KDO34275.1 - 1e-09 38.9 0.0 1.2e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KDO34275.1 - 0.048 13.4 10.8 0.062 13.1 5.4 3.3 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KDO34275.1 - 0.074 12.0 0.0 0.37 9.7 0.0 2.1 2 1 0 2 2 2 0 L-fucokinase Polyketide_cyc2 PF10604.9 KDO34276.1 - 0.041 14.2 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Aldedh PF00171.22 KDO34277.1 - 2.6e-38 131.7 0.0 3.8e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family U3_assoc_6 PF08640.11 KDO34278.1 - 3.2e-29 100.8 3.8 9e-29 99.4 3.8 1.8 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KDO34278.1 - 2.2e-08 34.2 14.4 0.36 11.8 1.1 8.0 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34278.1 - 1.6e-06 28.5 0.2 0.048 14.2 0.0 5.2 7 1 0 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KDO34278.1 - 0.0018 17.5 12.4 0.0096 15.1 2.0 4.0 3 1 2 5 5 5 2 NRDE-2, necessary for RNA interference DUF2594 PF10769.9 KDO34278.1 - 0.0044 17.0 0.3 0.035 14.1 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2594) Suf PF05843.14 KDO34278.1 - 0.0058 16.7 1.0 9.9 6.0 0.0 3.8 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_9 PF13371.6 KDO34278.1 - 0.28 11.4 3.7 0.89 9.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO34278.1 - 1 10.0 7.0 2.1 9.1 0.8 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_RNApol_7kD PF03604.13 KDO34279.1 - 2.7e-14 52.6 6.9 3.7e-14 52.1 6.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Nudix_N_2 PF14803.6 KDO34279.1 - 0.0048 16.8 1.0 0.47 10.4 0.1 2.2 2 0 0 2 2 2 2 Nudix N-terminal DZR PF12773.7 KDO34279.1 - 0.031 14.3 0.2 0.048 13.7 0.2 1.3 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KDO34279.1 - 0.056 13.0 0.1 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_13 PF09855.9 KDO34279.1 - 0.076 13.2 1.2 0.12 12.6 0.1 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-Mss51 PF13824.6 KDO34279.1 - 0.099 12.8 1.3 0.94 9.6 0.1 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HypA PF01155.19 KDO34279.1 - 0.1 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KDO34279.1 - 0.11 13.2 0.4 0.11 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rubredoxin_2 PF18073.1 KDO34279.1 - 0.79 9.5 5.0 4 7.2 0.3 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain NMD3 PF04981.13 KDO34280.1 - 7.4e-79 264.6 4.1 7.4e-79 264.6 4.1 1.8 2 0 0 2 2 2 1 NMD3 family TPR_8 PF13181.6 KDO34281.1 - 0.0045 17.1 3.3 0.81 10.1 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO34281.1 - 0.18 12.5 2.9 2.5 9.0 2.9 3.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34281.1 - 0.36 10.7 2.8 1e+02 2.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34281.1 - 6 7.4 16.2 0.37 11.3 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L9_N PF01281.19 KDO34282.1 - 1.2e-19 69.6 3.3 2.8e-19 68.4 0.7 2.3 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 KDO34282.1 - 1.3e-09 38.4 0.2 3.3e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain DUF531 PF04407.12 KDO34282.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) DUF543 PF04418.12 KDO34283.1 - 6.2e-20 71.0 0.3 7.3e-20 70.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ApoL PF05461.11 KDO34283.1 - 0.055 12.8 0.1 0.059 12.7 0.1 1.0 1 0 0 1 1 1 0 Apolipoprotein L DUF3767 PF12597.8 KDO34283.1 - 0.47 10.3 3.7 2.5 8.0 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3767) UAA PF08449.11 KDO34284.1 - 1.7e-51 175.2 17.6 1e-49 169.4 17.6 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KDO34284.1 - 6.9e-06 25.6 14.2 6.8e-05 22.3 1.7 2.5 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 KDO34284.1 - 1e-05 25.7 28.8 0.00032 20.9 10.6 2.8 2 2 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 KDO34284.1 - 3.7e-05 22.8 2.9 3.7e-05 22.8 2.9 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KDO34284.1 - 0.0049 16.1 5.5 0.07 12.3 2.2 2.4 1 1 1 2 2 2 2 Nucleotide-sugar transporter YEATS PF03366.16 KDO34285.1 - 4.2e-29 100.3 0.0 7e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 YEATS family FHA PF00498.26 KDO34286.1 - 1.7e-12 47.5 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KDO34286.1 - 8.1e-07 29.3 0.0 2.3e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF2508 PF10704.9 KDO34286.1 - 0.063 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) RRM_1 PF00076.22 KDO34287.1 - 2e-16 59.6 0.0 3.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Guanylate_cyc PF00211.20 KDO34288.1 - 6.5e-12 45.4 0.1 1.7e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KDO34288.1 - 0.00086 19.7 5.5 0.024 15.0 0.6 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KDO34288.1 - 0.0038 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KDO34288.1 - 0.0053 16.5 0.0 0.08 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Exo_endo_phos PF03372.23 KDO34289.1 - 2e-18 66.8 0.2 6.8e-18 65.0 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tower PF09121.10 KDO34289.1 - 0.0081 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Tower Ku PF02735.16 KDO34290.1 - 8.2e-49 166.1 0.0 1.3e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KDO34290.1 - 1.4e-25 90.4 0.0 2.7e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KDO34290.1 - 1.8e-11 44.5 0.1 4.7e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KDO34290.1 - 1.3e-08 34.4 0.1 3.9e-08 32.9 0.1 1.9 1 0 0 1 1 1 1 SAP domain Phage_TAC_5 PF08890.11 KDO34290.1 - 0.045 13.8 0.1 0.43 10.6 0.1 2.2 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC SMI1_KNR4 PF09346.10 KDO34291.1 - 7e-09 36.2 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KDO34291.1 - 2.2e-05 24.9 0.0 6.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall fn3 PF00041.21 KDO34292.1 - 7.4e-12 45.5 0.1 1.8e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain TSP_1 PF00090.19 KDO34292.1 - 7.2e-05 22.9 2.5 7.2e-05 22.9 2.5 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain GPI-anchored PF10342.9 KDO34292.1 - 0.0063 17.3 0.2 0.014 16.1 0.2 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EGF PF00008.27 KDO34292.1 - 0.014 15.7 5.0 0.042 14.2 5.0 1.9 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 KDO34292.1 - 0.02 15.3 0.7 0.02 15.3 0.7 2.4 2 1 0 2 2 2 0 EGF-like domain Pur_ac_phosph_N PF16656.5 KDO34292.1 - 0.039 14.5 0.0 0.081 13.5 0.0 1.4 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain EGF_alliinase PF04863.13 KDO34292.1 - 0.075 13.4 5.4 0.19 12.1 5.4 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain fn3_4 PF16794.5 KDO34292.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Fibronectin-III type domain DUF1179 PF06678.11 KDO34292.1 - 2.6 8.1 6.0 0.27 11.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Synaptobrevin PF00957.21 KDO34293.1 - 1.1e-06 28.4 0.2 2.4e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Synaptobrevin ANAPC4_WD40 PF12894.7 KDO34293.1 - 5e-05 23.5 0.0 0.059 13.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PDZ_6 PF17820.1 KDO34293.1 - 0.023 14.5 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.32 KDO34293.1 - 0.43 11.5 2.5 1.4 9.9 0.2 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.32 KDO34294.1 - 6.2e-23 80.7 14.7 6.8e-06 26.7 0.2 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34294.1 - 8.5e-06 26.0 0.1 0.33 11.3 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KDO34294.1 - 0.061 12.0 3.6 30 3.1 0.0 4.5 5 2 1 6 6 6 0 Nucleoporin Nup120/160 DnaJ PF00226.31 KDO34295.1 - 2.6e-20 72.3 0.1 4.2e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4264 PF14084.6 KDO34295.1 - 0.21 11.3 0.0 0.46 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) His_Phos_1 PF00300.22 KDO34296.1 - 2.7e-16 59.9 0.5 2e-15 57.0 0.5 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DTW PF03942.15 KDO34297.1 - 1.9e-16 60.3 0.0 7e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 DTW domain zf-CCHC PF00098.23 KDO34297.1 - 0.017 15.1 3.3 0.017 15.1 3.3 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KDO34297.1 - 0.061 13.1 0.6 0.061 13.1 0.6 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KDO34298.1 - 0.0037 17.3 3.4 0.0037 17.3 3.4 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KDO34298.1 - 0.012 15.4 0.6 0.012 15.4 0.6 2.3 1 1 1 2 2 2 0 Zinc knuckle TPR_1 PF00515.28 KDO34299.1 - 1.6e-07 30.9 1.9 0.0073 16.1 0.2 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34299.1 - 6.3e-07 29.8 10.8 2.4e-05 24.7 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34299.1 - 3e-06 27.4 9.3 0.0012 19.1 0.4 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34299.1 - 1.5e-05 25.0 2.7 0.021 15.0 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34299.1 - 4.6e-05 23.2 11.3 0.024 14.7 0.2 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34299.1 - 0.00049 19.9 0.4 0.022 14.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KDO34299.1 - 0.0018 17.7 2.1 0.0018 17.7 2.1 3.0 3 0 0 3 3 3 1 MalT-like TPR region TPR_8 PF13181.6 KDO34299.1 - 0.0019 18.2 2.6 0.13 12.5 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO34299.1 - 0.0052 17.0 2.6 0.017 15.4 0.0 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KDO34299.1 - 0.0071 17.0 0.0 0.0071 17.0 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34299.1 - 0.011 16.5 12.4 0.18 12.7 0.2 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34299.1 - 0.019 15.6 0.3 0.019 15.6 0.3 4.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Tcf25 PF04910.14 KDO34299.1 - 0.051 12.6 0.5 0.37 9.8 0.1 2.4 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Peroxin-3 PF04882.12 KDO34299.1 - 0.33 9.9 3.1 0.47 9.4 3.1 1.2 1 0 0 1 1 1 0 Peroxin-3 Mito_carr PF00153.27 KDO34300.1 - 2.5e-33 113.9 4.2 3.5e-16 58.9 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Sensor_TM1 PF13755.6 KDO34301.1 - 0.053 13.3 0.6 0.079 12.7 0.6 1.2 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain TRAP_beta PF05753.14 KDO34301.1 - 0.15 11.4 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) DS PF01916.17 KDO34302.1 - 9.5e-135 448.4 0.0 1.1e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sigma_reg_N PF13800.6 KDO34303.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Aminotran_5 PF00266.19 KDO34304.1 - 5.3e-57 193.5 0.2 4.3e-56 190.5 0.2 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KDO34304.1 - 8.9e-07 27.8 0.0 1.5e-06 27.0 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KDO34304.1 - 1.1e-05 25.0 1.0 1.6e-05 24.4 1.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SpoU_methylase PF00588.19 KDO34304.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 SpoU rRNA Methylase family Fcf1 PF04900.12 KDO34305.1 - 2.5e-17 63.1 0.0 4.5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KDO34305.1 - 9.7e-08 32.3 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Pkinase PF00069.25 KDO34306.1 - 1.1e-68 231.5 0.0 1.8e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KDO34306.1 - 1.4e-59 198.2 0.3 9.9e-21 73.6 0.0 4.0 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO34306.1 - 7.9e-35 120.4 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO34306.1 - 0.0022 17.9 0.0 0.02 14.8 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO34306.1 - 0.0082 15.5 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KDO34306.1 - 0.096 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_S28 PF05577.12 KDO34307.1 - 1.1e-66 225.5 0.0 1.3e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KDO34307.1 - 1e-05 24.5 0.0 1.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 KDO34307.1 - 3.1e-05 23.8 0.1 8.5e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO34307.1 - 0.0024 17.2 0.1 0.0043 16.3 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DEAD PF00270.29 KDO34308.1 - 1.9e-37 128.7 0.1 5e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO34308.1 - 9.9e-28 96.7 0.6 5.5e-25 87.9 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KDO34308.1 - 0.015 14.1 0.2 4.1 6.1 0.1 2.8 4 0 0 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Red1 PF07964.11 KDO34308.1 - 1.6 6.9 19.0 2.7 6.1 19.0 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Dicty_REP PF05086.12 KDO34308.1 - 6.8 4.5 11.2 11 3.9 11.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tetraspanin PF00335.20 KDO34309.1 - 1.3e-18 67.6 12.5 2.9e-18 66.5 12.5 1.5 1 1 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KDO34309.1 - 0.016 14.8 1.1 0.016 14.8 1.1 2.9 4 0 0 4 4 4 0 SUR7/PalI family DUF2062 PF09835.9 KDO34309.1 - 0.099 12.5 0.0 0.099 12.5 0.0 3.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2981 PF11200.8 KDO34309.1 - 0.15 11.8 5.7 0.3 10.8 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2615 PF11027.8 KDO34309.1 - 0.16 12.1 0.1 2.2 8.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) HpcH_HpaI PF03328.14 KDO34309.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF4743 PF15916.5 KDO34310.1 - 1.8e-21 76.3 0.1 2.8e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KDO34310.1 - 7.2e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TPR_1 PF00515.28 KDO34311.1 - 2.2e-19 68.4 2.3 0.0012 18.6 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34311.1 - 1.4e-17 62.3 4.2 0.00092 19.2 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 KDO34311.1 - 1.9e-14 53.1 1.5 0.0015 18.2 0.0 4.4 1 1 3 4 4 4 4 TPR repeat cNMP_binding PF00027.29 KDO34311.1 - 1.3e-10 41.2 0.1 0.0095 16.0 0.0 4.2 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain TPR_16 PF13432.6 KDO34311.1 - 9.9e-09 35.7 3.1 0.00015 22.3 0.2 3.7 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO34311.1 - 9.4e-08 31.9 0.9 0.4 11.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34311.1 - 9.6e-07 29.2 0.1 0.066 13.7 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34311.1 - 6.5e-05 22.8 0.4 0.44 10.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34311.1 - 0.00014 22.1 5.4 0.0075 16.5 0.6 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34311.1 - 0.00084 20.0 14.2 0.11 13.4 0.1 4.9 4 2 2 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34311.1 - 0.0095 15.9 6.0 0.56 10.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34311.1 - 0.012 15.7 0.6 0.36 11.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KDO34311.1 - 0.21 12.0 2.5 3.5 8.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KDO34311.1 - 0.43 10.5 2.5 56 3.8 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO34312.1 - 3.5e-74 249.5 0.0 5.2e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34312.1 - 4e-32 111.5 0.0 6.5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KDO34312.1 - 4.3e-25 85.3 7.9 3.5e-08 32.4 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KDO34312.1 - 1.3e-22 80.0 1.7 4.1e-10 40.0 0.8 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO34312.1 - 1.5e-20 71.3 6.4 1.7e-05 24.4 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KDO34312.1 - 6.6e-19 66.5 5.7 1.9e-05 23.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KDO34312.1 - 1.2e-18 66.7 7.7 7.4e-09 35.3 0.7 3.5 1 1 2 3 3 3 3 EF-hand domain pair Kdo PF06293.14 KDO34312.1 - 6.8e-07 28.9 0.1 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 KDO34312.1 - 3.7e-05 24.0 0.2 0.65 10.4 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain APH PF01636.23 KDO34312.1 - 8.8e-05 22.5 0.0 0.00084 19.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 KDO34312.1 - 0.00012 22.0 1.6 0.092 12.7 0.1 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KDO34312.1 - 0.00081 19.7 0.0 0.77 10.1 0.1 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Choline_kinase PF01633.20 KDO34312.1 - 0.0011 18.6 0.0 0.0033 17.1 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Caleosin PF05042.13 KDO34312.1 - 0.017 15.0 0.2 1.8 8.5 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein EcKinase PF02958.20 KDO34312.1 - 0.05 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RNB PF00773.19 KDO34313.1 - 3.5e-86 289.5 0.0 5.2e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KDO34313.1 - 4.1e-17 62.0 0.0 9.9e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 KDO34313.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KDO34313.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 KDO34313.1 - 0.02 15.1 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 0 Cold shock domain OB_RNB PF08206.11 KDO34313.1 - 0.031 14.0 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain TPR_12 PF13424.6 KDO34314.1 - 4.2e-24 84.6 22.5 5.4e-12 45.8 1.1 6.1 3 2 3 6 6 6 5 Tetratricopeptide repeat Ank_4 PF13637.6 KDO34314.1 - 8e-18 64.6 8.6 5.9e-11 42.7 1.0 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34314.1 - 1.6e-16 60.7 6.6 2.6e-09 37.5 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34314.1 - 2.5e-15 56.3 10.5 2.9e-08 33.8 1.4 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34314.1 - 5.5e-14 50.9 7.0 2.2e-05 24.5 0.1 4.9 5 0 0 5 5 4 3 Ankyrin repeat Ank PF00023.30 KDO34314.1 - 3e-13 49.5 10.6 7.7e-08 32.4 0.3 4.7 4 1 0 4 4 4 2 Ankyrin repeat TPR_10 PF13374.6 KDO34314.1 - 3.3e-07 30.0 27.0 0.0039 17.0 0.3 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34314.1 - 0.0014 18.3 4.7 0.99 9.3 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34314.1 - 0.012 15.7 13.5 0.35 11.1 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34314.1 - 0.022 14.8 7.1 3 8.1 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN6_N PF18055.1 KDO34314.1 - 0.076 13.4 0.3 0.58 10.5 0.1 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_3 PF07720.12 KDO34314.1 - 0.11 12.6 2.2 1.2 9.3 1.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34314.1 - 0.17 12.8 13.4 3.6 8.6 0.5 5.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34314.1 - 0.22 12.2 5.4 50 4.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO34314.1 - 0.46 11.2 12.5 1.3 9.8 1.5 4.7 2 2 1 3 3 3 0 Tetratricopeptide repeat zf-ZPR1 PF03367.13 KDO34315.1 - 5.6e-106 351.3 0.0 1.9e-55 187.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Kinesin PF00225.23 KDO34317.1 - 7.5e-48 163.2 0.0 1.5e-47 162.2 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO34317.1 - 1.9e-13 50.6 0.0 3.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 KDO34317.1 - 4.1e-05 23.7 0.0 9.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 KDO34317.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KDO34317.1 - 0.1 12.5 0.1 0.34 10.9 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif MOFRL PF05161.13 KDO34317.1 - 0.11 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 MOFRL family ANAPC4_WD40 PF12894.7 KDO34318.1 - 5.1e-05 23.5 0.0 0.047 14.0 0.0 3.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Med16 PF11635.8 KDO34318.1 - 0.057 11.3 0.0 0.067 11.1 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 WD40 PF00400.32 KDO34318.1 - 0.086 13.8 3.6 0.22 12.5 0.1 3.3 4 1 1 5 5 5 0 WD domain, G-beta repeat WD40 PF00400.32 KDO34321.1 - 3.6e-07 30.8 3.3 9.4e-05 23.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KDO34321.1 - 0.00015 21.6 3.3 0.00018 21.3 1.6 2.1 1 1 1 2 2 2 1 F-box-like Nup160 PF11715.8 KDO34321.1 - 0.069 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Oxidored_q3 PF00499.20 KDO34322.1 - 0.0014 18.3 2.5 0.0014 18.3 2.5 2.5 2 1 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Apo-CIII PF05778.12 KDO34322.1 - 0.091 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Cadherin_5 PF17892.1 KDO34322.1 - 0.14 12.2 0.1 0.41 10.6 0.1 1.8 1 0 0 1 1 1 0 Cadherin-like domain Peptidase_M14 PF00246.24 KDO34323.1 - 2e-39 136.1 0.0 2.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CH PF00307.31 KDO34324.1 - 4.6e-06 26.8 0.0 1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Calponin homology (CH) domain DUF5005 PF16396.5 KDO34324.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) LOR PF04525.12 KDO34325.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 LURP-one-related Hydrolase_4 PF12146.8 KDO34326.1 - 9.6e-54 182.2 0.0 1.2e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO34326.1 - 4.6e-13 49.4 0.2 5.7e-08 32.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO34326.1 - 6.6e-12 46.5 0.2 6.6e-12 46.5 0.2 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KDO34326.1 - 1.2e-05 24.9 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KDO34326.1 - 5.2e-05 23.0 0.1 0.0006 19.5 0.1 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KDO34326.1 - 0.1 12.3 0.0 2.5 7.9 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Mito_carr PF00153.27 KDO34327.1 - 6.9e-63 208.6 0.2 4.3e-23 81.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KDO34328.1 - 3.4e-27 94.2 4.6 4.2e-12 45.8 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Dicty_REP PF05086.12 KDO34331.1 - 8.3 4.2 6.0 15 3.4 6.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hexapep PF00132.24 KDO34332.1 - 2.5e-18 65.0 24.6 4.9e-07 29.2 0.9 6.2 3 2 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 KDO34332.1 - 5.6e-12 45.9 0.2 1.2e-11 44.8 0.2 1.6 1 1 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 KDO34332.1 - 0.0032 17.2 16.7 0.62 9.9 0.2 5.3 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase BLOC1_2 PF10046.9 KDO34333.1 - 1.2e-15 57.5 4.1 1.5e-15 57.3 4.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KDO34333.1 - 0.00044 19.2 2.0 0.00048 19.1 2.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 KDO34333.1 - 0.0042 16.7 2.2 0.0046 16.6 2.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Cucumo_coat PF00760.18 KDO34333.1 - 0.0043 16.7 0.3 0.0046 16.6 0.3 1.0 1 0 0 1 1 1 1 Cucumovirus coat protein Pepsin-I3 PF06394.13 KDO34333.1 - 0.0052 17.0 0.1 0.17 12.1 0.0 2.1 2 0 0 2 2 2 1 Pepsin inhibitor-3-like repeated domain COG5 PF10392.9 KDO34333.1 - 0.01 16.0 0.9 0.076 13.2 0.2 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Snapin_Pallidin PF14712.6 KDO34333.1 - 0.011 16.2 3.0 1.7 9.1 0.6 2.2 2 0 0 2 2 2 0 Snapin/Pallidin UPF0242 PF06785.11 KDO34333.1 - 0.028 14.5 1.8 0.029 14.5 1.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 KDO34333.1 - 0.032 14.3 1.0 0.043 13.8 1.0 1.2 1 0 0 1 1 1 0 Laminin Domain II Osmo_CC PF08946.10 KDO34333.1 - 0.038 14.2 0.5 0.093 13.0 0.5 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil CLZ PF16526.5 KDO34333.1 - 0.042 14.2 4.4 0.78 10.1 0.4 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CHASE7 PF17151.4 KDO34333.1 - 0.06 12.9 1.1 0.072 12.7 0.6 1.5 1 1 0 1 1 1 0 Periplasmic sensor domain DUF4446 PF14584.6 KDO34333.1 - 0.068 13.2 1.1 0.11 12.5 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 KDO34333.1 - 0.08 13.0 2.5 0.67 10.0 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 KDO34333.1 - 0.11 11.1 0.4 0.12 10.9 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dam1 PF08653.10 KDO34333.1 - 0.13 12.0 2.4 3.7 7.4 0.3 2.6 1 1 0 2 2 2 0 DASH complex subunit Dam1 V-SNARE PF05008.15 KDO34333.1 - 0.16 12.4 3.1 0.24 11.8 2.2 1.8 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Metalloenzyme PF01676.18 KDO34333.1 - 0.23 10.8 0.4 0.27 10.5 0.4 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF2205 PF10224.9 KDO34333.1 - 0.27 11.2 4.1 8.8 6.4 0.2 2.2 1 1 1 2 2 2 0 Short coiled-coil protein zf-C4H2 PF10146.9 KDO34333.1 - 0.39 11.0 2.7 0.43 10.8 2.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Rx_N PF18052.1 KDO34333.1 - 0.84 10.0 5.0 1.4 9.3 5.0 1.5 1 1 0 1 1 1 0 Rx N-terminal domain Guanylate_cyc PF00211.20 KDO34334.1 - 1.6e-08 34.4 0.0 3.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UCR_TM PF02921.14 KDO34334.1 - 0.058 13.9 5.1 0.16 12.5 0.1 3.3 3 1 0 3 3 3 0 Ubiquinol cytochrome reductase transmembrane region Ank_2 PF12796.7 KDO34335.1 - 1.8e-38 131.0 17.7 6e-11 42.8 1.5 7.0 4 3 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34335.1 - 1.2e-24 86.3 14.8 8.2e-07 29.5 0.2 8.2 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34335.1 - 3.5e-23 79.2 15.9 0.0075 16.7 0.1 11.5 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 KDO34335.1 - 1.9e-21 75.8 25.2 0.0056 17.0 1.3 11.1 7 3 5 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 KDO34335.1 - 1.9e-20 72.3 28.4 0.00026 21.3 0.1 10.4 8 2 1 9 9 9 6 Ankyrin repeat Ion_trans PF00520.31 KDO34335.1 - 0.00065 19.0 17.4 0.0012 18.1 17.4 1.4 1 0 0 1 1 1 1 Ion transport protein TraQ PF09679.10 KDO34335.1 - 0.37 10.7 2.2 16 5.5 0.6 2.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) TMF_TATA_bd PF12325.8 KDO34335.1 - 1.1 9.5 8.8 0.23 11.7 3.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ion_trans PF00520.31 KDO34337.1 - 0.006 15.9 6.4 0.0089 15.3 6.4 1.2 1 0 0 1 1 1 1 Ion transport protein Lectin_N PF03954.14 KDO34337.1 - 0.11 12.2 5.9 0.18 11.6 1.8 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Apolipoprotein PF01442.18 KDO34337.1 - 0.12 12.2 17.1 0.35 10.7 16.4 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YabA PF06156.13 KDO34337.1 - 6.4 7.5 10.9 6.3 7.5 0.6 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Pkinase PF00069.25 KDO34338.1 - 2.8e-58 197.4 0.0 4e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34338.1 - 1.2e-28 100.1 0.0 1.9e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34338.1 - 0.00043 19.7 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 KDO34338.1 - 0.004 17.7 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.23 KDO34338.1 - 0.048 13.6 0.9 0.19 11.6 0.1 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family AAA PF00004.29 KDO34339.1 - 1.3e-43 148.6 0.1 3.2e-43 147.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO34339.1 - 4.2e-11 42.5 0.1 1.3e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KDO34339.1 - 1.9e-06 27.9 0.2 1.2e-05 25.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO34339.1 - 3.2e-06 27.4 0.0 6.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KDO34339.1 - 7.5e-06 26.4 0.1 9.9e-05 22.8 0.1 2.3 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KDO34339.1 - 4.2e-05 23.3 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KDO34339.1 - 4.7e-05 23.7 0.2 0.0068 16.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO34339.1 - 0.0013 19.0 0.0 0.0021 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KDO34339.1 - 0.0019 17.9 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KDO34339.1 - 0.0023 17.4 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.26 KDO34339.1 - 0.0023 17.7 0.1 0.033 13.9 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 KDO34339.1 - 0.0026 17.0 0.0 0.0049 16.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KDO34339.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KDO34339.1 - 0.0039 16.6 0.1 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KDO34339.1 - 0.0045 17.5 0.0 0.012 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KDO34339.1 - 0.005 17.1 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KDO34339.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KDO34339.1 - 0.017 14.5 0.0 0.062 12.6 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 KDO34339.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO34339.1 - 0.018 15.4 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KDO34339.1 - 0.02 14.6 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO34339.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KDO34339.1 - 0.028 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KDO34339.1 - 0.041 13.9 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KDO34339.1 - 0.042 13.4 0.0 0.099 12.2 0.0 1.5 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KDO34339.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KDO34339.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.6 KDO34339.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KDO34339.1 - 0.13 12.6 0.1 0.38 11.1 0.1 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 KDO34339.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ubiquitin PF00240.23 KDO34340.1 - 2e-07 30.6 0.4 5.5e-07 29.3 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KDO34340.1 - 7.1e-05 23.2 0.1 0.00031 21.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KDO34340.1 - 0.0027 17.5 0.5 0.018 14.9 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KDO34340.1 - 0.016 15.2 0.4 0.079 13.0 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain RAWUL PF16207.5 KDO34340.1 - 0.054 14.2 0.0 0.07 13.8 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Tyrosinase PF00264.20 KDO34342.1 - 5.6e-20 72.6 3.9 9.3e-10 39.2 1.6 2.7 1 1 1 2 2 2 2 Common central domain of tyrosinase PAN_1 PF00024.26 KDO34342.1 - 8.1e-19 67.4 17.6 3e-06 27.1 1.4 3.7 2 1 1 3 3 3 3 PAN domain PAN_4 PF14295.6 KDO34342.1 - 2.9e-15 55.9 38.4 1.1e-05 25.2 5.6 4.0 4 0 0 4 4 4 3 PAN domain HTH_OrfB_IS605 PF12323.8 KDO34342.1 - 0.0029 17.1 3.8 0.47 10.0 0.0 3.5 3 0 0 3 3 3 2 Helix-turn-helix domain Trypan_PARP PF05887.11 KDO34342.1 - 0.0078 16.2 1.6 0.0087 16.0 0.2 1.8 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) WD40 PF00400.32 KDO34344.1 - 1.1e-16 60.9 17.0 1.2e-05 25.9 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KDO34344.1 - 3.1e-16 59.4 0.1 8.3e-15 54.8 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KDO34344.1 - 1.5e-09 38.0 0.9 0.005 17.1 0.2 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_25 PF13649.6 KDO34345.1 - 4.2e-10 40.2 0.0 8.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO34345.1 - 6.2e-09 35.8 0.0 8.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO34345.1 - 5.6e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KDO34345.1 - 0.00039 19.8 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UDG PF03167.19 KDO34346.1 - 0.0019 18.2 0.0 0.0083 16.1 0.0 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily GMC_oxred_N PF00732.19 KDO34347.1 - 2.1e-27 96.2 0.6 1.2e-26 93.9 0.6 2.1 1 1 0 1 1 1 1 GMC oxidoreductase PAN_4 PF14295.6 KDO34347.1 - 1.7e-21 75.8 33.9 5.1e-09 35.9 6.0 3.8 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KDO34347.1 - 9.4e-15 54.4 14.3 3.3e-05 23.8 3.4 3.7 2 1 1 3 3 3 3 PAN domain GMC_oxred_C PF05199.13 KDO34347.1 - 5e-09 36.8 0.2 1.9e-08 34.9 0.0 2.1 3 0 0 3 3 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KDO34347.1 - 1.9e-07 30.5 0.8 3.3e-06 26.5 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KDO34347.1 - 2.7e-05 24.3 2.3 7.1e-05 23.0 0.2 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KDO34347.1 - 0.00015 21.1 1.1 0.00015 21.1 1.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KDO34347.1 - 0.00022 20.6 0.1 0.00042 19.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KDO34347.1 - 0.0048 16.2 0.3 0.0076 15.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KDO34347.1 - 0.0064 16.1 1.5 0.014 15.0 1.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KDO34347.1 - 0.0065 15.2 0.3 0.0094 14.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KDO34347.1 - 0.022 14.0 1.1 0.032 13.5 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KDO34347.1 - 0.097 11.7 0.4 0.17 10.9 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein PAN_2 PF08276.11 KDO34347.1 - 3.9 7.7 28.6 0.42 10.8 3.9 3.5 3 0 0 3 3 3 0 PAN-like domain RabGAP-TBC PF00566.18 KDO34348.1 - 9e-07 28.8 0.1 1.3e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GMC_oxred_N PF00732.19 KDO34349.1 - 3.9e-22 79.0 0.9 2.1e-21 76.6 0.1 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KDO34349.1 - 7.7e-12 45.9 0.3 1.6e-11 44.9 0.1 1.6 2 0 0 2 2 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KDO34349.1 - 2.9e-06 27.4 2.1 1.6e-05 25.0 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KDO34349.1 - 5.3e-06 25.8 1.0 1.8e-05 24.1 1.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KDO34349.1 - 2.4e-05 23.7 1.2 4.5e-05 22.8 0.7 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KDO34349.1 - 0.00025 20.4 0.9 0.00039 19.8 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KDO34349.1 - 0.00054 19.2 2.6 0.00094 18.4 2.6 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KDO34349.1 - 0.0026 16.5 0.7 0.0044 15.8 0.7 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KDO34349.1 - 0.0043 16.7 1.5 0.0084 15.7 1.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO34349.1 - 0.0043 16.1 0.5 0.0083 15.2 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KDO34349.1 - 0.19 11.0 2.2 0.32 10.3 2.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KDO34349.1 - 0.53 9.5 2.3 0.44 9.7 0.7 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAN_4 PF14295.6 KDO34350.1 - 7.8e-31 105.7 41.3 7.9e-09 35.3 4.8 4.7 4 0 0 4 4 4 4 PAN domain GMC_oxred_N PF00732.19 KDO34350.1 - 7.9e-26 91.1 1.1 3.6e-25 88.9 1.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase PAN_1 PF00024.26 KDO34350.1 - 3.1e-18 65.5 16.8 0.00038 20.4 0.7 4.4 3 1 1 4 4 4 4 PAN domain GMC_oxred_C PF05199.13 KDO34350.1 - 1.6e-08 35.2 0.1 8.6e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KDO34350.1 - 1.7e-06 27.4 0.2 4e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KDO34350.1 - 6.9e-06 25.5 0.2 1.6e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KDO34350.1 - 3.1e-05 24.1 0.1 0.00014 22.0 0.1 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KDO34350.1 - 0.00032 20.0 0.5 0.00063 19.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KDO34350.1 - 0.00097 18.8 1.0 0.0024 17.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KDO34350.1 - 0.011 15.0 0.4 0.017 14.4 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KDO34350.1 - 0.015 14.0 0.2 0.027 13.2 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KDO34350.1 - 0.018 14.1 1.4 0.082 11.9 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KDO34350.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KDO34350.1 - 0.29 10.2 1.4 6.3 5.8 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Asparaginase_2 PF01112.18 KDO34351.1 - 2.7e-77 259.8 0.2 3.5e-77 259.4 0.2 1.0 1 0 0 1 1 1 1 Asparaginase Metallophos PF00149.28 KDO34352.1 - 7.4e-39 134.4 0.1 1e-38 133.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_6 PF13516.6 KDO34353.1 - 1.9e-11 43.1 27.5 0.0054 16.7 0.3 8.2 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 KDO34353.1 - 0.0011 19.2 8.4 1.9 9.4 0.1 5.6 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 KDO34353.1 - 0.0056 17.1 1.9 0.0056 17.1 1.9 4.7 2 1 4 6 6 6 3 Leucine Rich repeats (2 copies) Lung_7-TM_R PF06814.13 KDO34354.1 - 5.6e-16 58.6 13.4 8.9e-16 58.0 13.4 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KDO34354.1 - 1.3e-09 37.9 7.3 2.9e-09 36.7 7.2 1.6 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain zf-SNAP50_C PF12251.8 KDO34355.1 - 9.6e-44 149.5 0.5 1.4e-43 148.9 0.5 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal OrfB_Zn_ribbon PF07282.11 KDO34355.1 - 0.2 11.6 0.5 0.37 10.8 0.5 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain LIM PF00412.22 KDO34355.1 - 0.3 11.3 4.7 0.3 11.3 3.1 1.8 2 0 0 2 2 2 0 LIM domain Pkinase PF00069.25 KDO34356.1 - 6.5e-63 212.6 0.0 1.2e-62 211.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34356.1 - 2.1e-36 125.5 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 KDO34356.1 - 1.2e-07 31.7 14.6 2.6e-07 30.7 14.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO34356.1 - 0.0044 17.2 9.8 0.0094 16.2 9.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Kinase-like PF14531.6 KDO34356.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Hs1pro-1_C PF07014.12 KDO34357.1 - 3.9e-10 39.7 0.4 6.6e-09 35.6 0.4 2.2 1 1 0 1 1 1 1 Hs1pro-1 protein C-terminus Trp_dioxygenase PF03301.13 KDO34357.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase RMI1_C PF16099.5 KDO34357.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Cyclin PF08613.11 KDO34358.1 - 1.9e-12 47.9 0.0 2.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KDO34358.1 - 1.7e-09 37.5 0.2 4e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain WW PF00397.26 KDO34358.1 - 2.9e-08 33.7 2.9 2.9e-08 33.7 2.9 2.1 2 0 0 2 2 2 1 WW domain Pkinase PF00069.25 KDO34359.1 - 2.8e-59 200.6 0.0 4.1e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34359.1 - 1e-41 143.0 0.0 1.5e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34359.1 - 1.4e-08 34.4 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO34359.1 - 0.00011 21.1 0.2 0.00022 20.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO34359.1 - 0.025 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3246 PF11596.8 KDO34359.1 - 0.098 12.1 2.3 0.15 11.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 KDO34359.1 - 0.59 10.5 7.8 1.4 9.3 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KDO34359.1 - 0.76 9.0 6.2 1.4 8.2 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KDO34359.1 - 1 9.4 4.0 0.27 11.2 0.7 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal LRR_8 PF13855.6 KDO34360.1 - 7e-44 147.4 40.5 4.2e-08 32.8 1.7 9.9 5 3 6 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 KDO34360.1 - 4e-32 109.7 40.7 0.00012 22.3 0.1 11.3 8 4 2 12 12 12 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO34360.1 - 1.3e-08 34.2 34.2 12 7.0 0.0 15.1 15 2 0 15 15 15 1 Leucine Rich Repeat WW PF00397.26 KDO34360.1 - 7.2e-05 22.8 0.1 0.00023 21.2 0.1 1.9 1 0 0 1 1 1 1 WW domain LRR_6 PF13516.6 KDO34360.1 - 0.0076 16.2 35.2 5.8 7.2 0.1 12.3 14 0 0 14 14 14 1 Leucine Rich repeat LRR_9 PF14580.6 KDO34360.1 - 0.025 14.1 11.1 0.38 10.3 0.4 4.7 4 2 1 5 5 5 0 Leucine-rich repeat V-SNARE PF05008.15 KDO34360.1 - 0.12 12.8 2.0 0.44 11.0 0.2 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus HAD_2 PF13419.6 KDO34360.1 - 0.19 11.8 0.7 0.43 10.6 0.7 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AAA_13 PF13166.6 KDO34360.1 - 2 7.0 9.5 3.5 6.2 9.5 1.3 1 0 0 1 1 1 0 AAA domain CREPT PF16566.5 KDO34360.1 - 2.1 8.5 0.0 2.1 8.5 0.0 4.7 5 0 0 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour ING PF12998.7 KDO34360.1 - 4.8 7.8 5.8 9.3 6.9 0.3 3.3 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding HTH_28 PF13518.6 KDO34361.1 - 7.8e-09 35.5 0.0 0.33 11.1 0.0 4.5 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 KDO34361.1 - 8.1e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KDO34361.1 - 2.6e-06 27.0 0.0 0.067 12.8 0.0 3.3 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KDO34361.1 - 1.7e-05 24.5 3.1 0.29 11.0 0.0 5.0 4 2 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.6 KDO34361.1 - 1.9e-05 24.3 0.6 3.1 7.7 0.0 4.4 4 1 0 4 4 4 2 Helix-turn-helix domain Octopine_DH PF02317.17 KDO34361.1 - 0.00018 21.6 0.0 0.15 12.1 0.0 3.8 4 0 0 4 4 4 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain HTH_Tnp_ISL3 PF13542.6 KDO34361.1 - 0.0024 17.2 0.0 5 6.6 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 YdaS_antitoxin PF15943.5 KDO34361.1 - 0.0025 17.6 0.0 9.5 6.2 0.0 3.3 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_20 PF12840.7 KDO34361.1 - 0.0047 17.0 0.2 10 6.3 0.0 3.8 3 1 1 4 4 4 1 Helix-turn-helix domain HTH_5 PF01022.20 KDO34361.1 - 0.0056 16.5 0.0 6.2 6.8 0.0 3.3 3 1 0 3 3 3 1 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 KDO34361.1 - 0.0099 15.4 1.1 3.5 7.2 0.0 3.5 4 0 0 4 4 4 1 Sigma-70, region 4 MarR_2 PF12802.7 KDO34361.1 - 0.011 15.7 2.5 3.7 7.5 0.1 2.9 3 0 0 3 3 3 0 MarR family BrkDBD PF09607.10 KDO34361.1 - 0.038 13.8 0.8 0.95 9.3 0.0 2.9 4 0 0 4 4 4 0 Brinker DNA-binding domain GntR PF00392.21 KDO34361.1 - 0.061 13.0 0.7 6.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Mor PF08765.11 KDO34361.1 - 0.12 12.3 0.1 5.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Mor transcription activator family RNase_T PF00929.24 KDO34362.1 - 1.4e-12 48.5 0.0 2.3e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 Exonuclease zf_CCCH_4 PF18345.1 KDO34362.1 - 1.1e-09 38.1 17.8 1.9e-06 27.7 5.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KDO34362.1 - 6.1e-09 35.5 11.4 3.7e-07 29.8 1.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KDO34362.1 - 7.6e-09 35.3 14.1 7.5e-07 28.9 3.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KDO34362.1 - 2.8e-05 24.8 5.9 0.0017 19.0 0.4 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KDO34362.1 - 5.6e-05 23.5 14.5 0.0075 16.7 3.1 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KDO34362.1 - 8.3e-05 22.8 2.1 0.36 11.1 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger containing family DNA_pol_A_exo1 PF01612.20 KDO34362.1 - 0.0015 18.3 0.0 0.0055 16.4 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease 3Beta_HSD PF01073.19 KDO34363.1 - 1.4e-55 188.3 0.0 1.8e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KDO34363.1 - 6.4e-35 120.7 0.0 2.7e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KDO34363.1 - 7.5e-21 74.9 0.0 1.1e-19 71.0 0.0 2.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KDO34363.1 - 1.6e-17 63.5 0.1 3.1e-13 49.5 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KDO34363.1 - 6.1e-17 62.1 0.0 1.5e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Cyt-b5 PF00173.28 KDO34363.1 - 3.2e-16 59.2 0.0 6.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RmlD_sub_bind PF04321.17 KDO34363.1 - 5.2e-13 48.7 0.0 7.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KDO34363.1 - 1.1e-07 31.9 2.9 4.6e-06 26.7 2.9 2.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KDO34363.1 - 1.2e-06 27.8 0.3 8.3e-06 25.1 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KDO34363.1 - 8.2e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KDO34363.1 - 0.00068 19.2 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_7 PF13241.6 KDO34363.1 - 0.014 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KDO34363.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KDO34363.1 - 0.1 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SnoaL_3 PF13474.6 KDO34364.1 - 1.7e-16 60.6 0.0 3.1e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_3 PF07859.13 KDO34365.1 - 3.1e-40 138.3 0.0 4.5e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KDO34365.1 - 3e-11 42.8 0.0 4.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KDO34365.1 - 0.0064 15.4 0.2 0.16 10.8 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family PBP_sp32 PF07222.12 KDO34365.1 - 0.035 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Spt20 PF12090.8 KDO34366.1 - 0.051 13.2 15.0 0.078 12.6 15.0 1.2 1 0 0 1 1 1 0 Spt20 family Agenet PF05641.12 KDO34366.1 - 0.094 13.2 0.1 0.32 11.5 0.2 1.8 2 0 0 2 2 2 0 Agenet domain Suf PF05843.14 KDO34366.1 - 0.42 10.6 4.0 0.64 10.0 4.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 KDO34366.1 - 0.85 10.6 2.3 5 8.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 KDO34366.1 - 1.1 9.2 20.2 1.9 8.4 20.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 KDO34366.1 - 1.9 8.9 9.0 5.8 7.3 9.0 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Rrn6 PF10214.9 KDO34366.1 - 3 6.2 13.8 4.5 5.6 13.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CCT PF06203.14 KDO34367.1 - 5.3e-17 61.6 9.1 8e-17 61.0 9.1 1.2 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 KDO34367.1 - 0.63 10.0 3.1 1.2 9.1 3.1 1.5 1 0 0 1 1 1 0 Divergent CCT motif UAA PF08449.11 KDO34368.1 - 2.8e-06 26.8 3.0 5.1e-06 25.9 3.0 1.3 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 KDO34368.1 - 1.7e-05 24.5 4.3 4.1e-05 23.2 4.3 1.6 1 0 0 1 1 1 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 KDO34368.1 - 9.3e-05 21.7 2.2 0.00014 21.1 2.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KDO34368.1 - 0.00011 21.5 3.9 0.00019 20.8 3.9 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 KDO34368.1 - 0.00099 19.3 10.7 0.00099 19.3 10.7 3.2 2 1 1 3 3 3 2 EamA-like transporter family PPTA PF01239.22 KDO34369.1 - 1.2e-13 50.3 18.6 3.4e-06 26.6 0.8 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 KDO34369.1 - 0.067 13.6 0.8 4.8 7.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 KDO34370.1 - 1.3e-14 53.8 0.3 7.5e-14 51.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 KDO34370.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 Upf2 PF04050.14 KDO34370.1 - 9.5 7.0 10.4 1.9 9.2 7.1 1.5 2 0 0 2 2 2 0 Up-frameshift suppressor 2 DUF4483 PF14825.6 KDO34371.1 - 2.5e-28 98.8 0.0 4.5e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Lipase_3 PF01764.25 KDO34372.1 - 1.7e-29 102.5 0.0 4.1e-29 101.3 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 KDO34372.1 - 0.00053 19.6 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KDO34372.1 - 0.015 15.9 0.5 0.015 15.9 0.5 3.4 2 1 0 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KDO34372.1 - 0.14 11.9 0.1 0.62 9.7 0.1 1.9 2 0 0 2 2 2 0 PGAP1-like protein DUF498 PF04430.14 KDO34373.1 - 4e-31 107.3 0.0 5.2e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) PC4 PF02229.16 KDO34374.1 - 1.4e-39 133.5 1.2 6.2e-19 67.4 0.2 2.4 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) SRF-TF PF00319.18 KDO34375.1 - 2.8e-23 81.1 0.2 4.9e-23 80.3 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-TAZ PF02135.16 KDO34376.1 - 6.5e-15 55.4 26.0 7.9e-10 39.1 11.9 2.5 2 0 0 2 2 2 2 TAZ zinc finger TAF4 PF05236.14 KDO34376.1 - 2.6e-07 30.7 6.2 4.7e-07 29.8 6.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 KDO34376.1 - 0.0011 18.7 0.7 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit HLH PF00010.26 KDO34377.1 - 3.6e-09 36.4 0.6 7.7e-08 32.2 0.3 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KDO34377.1 - 0.037 14.3 1.1 0.065 13.5 1.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DHquinase_II PF01220.19 KDO34379.1 - 2.2e-05 24.2 0.1 0.00038 20.1 0.0 2.1 2 0 0 2 2 2 2 Dehydroquinase class II Yae1_N PF09811.9 KDO34380.1 - 9.3e-08 31.7 7.0 1.3e-07 31.2 7.0 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ribosomal_L29 PF00831.23 KDO34381.1 - 4.3e-19 68.2 1.2 4.3e-19 68.2 1.2 2.4 3 0 0 3 3 3 1 Ribosomal L29 protein Prominin PF05478.11 KDO34381.1 - 0.093 10.7 1.6 0.098 10.6 1.6 1.0 1 0 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 KDO34381.1 - 0.094 12.8 2.3 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Macro PF01661.21 KDO34382.1 - 1.4e-14 54.1 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Macro domain Macro PF01661.21 KDO34383.1 - 5e-14 52.4 0.0 8.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Macro domain Rad51 PF08423.11 KDO34384.1 - 1.2e-28 100.1 0.0 1.6e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KDO34384.1 - 1.7e-08 34.1 0.0 3.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KDO34384.1 - 5.8e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KDO34384.1 - 2.4e-05 24.0 0.1 5.6e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KDO34384.1 - 0.16 11.7 0.0 0.57 9.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF2306 PF10067.9 KDO34385.1 - 1.5e-13 51.2 3.9 1.8e-13 51.0 3.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 KDO34385.1 - 1.4e-05 25.4 4.9 0.017 15.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF420) CM2 PF03021.14 KDO34385.1 - 0.084 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M2 protein DUF2306 PF10067.9 KDO34386.1 - 5.6e-09 36.4 8.9 6.7e-09 36.1 8.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 KDO34386.1 - 0.00058 20.2 5.8 0.014 15.7 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF420) SLATT_1 PF18181.1 KDO34386.1 - 3.2 7.7 4.5 3.9 7.4 2.9 1.7 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2306 PF10067.9 KDO34387.1 - 1.2e-13 51.5 4.0 1.4e-13 51.3 4.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 KDO34387.1 - 0.0001 22.6 4.5 0.015 15.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF420) CM2 PF03021.14 KDO34387.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M2 protein 7TMR-DISM_7TM PF07695.11 KDO34387.1 - 0.14 12.1 0.4 0.24 11.3 0.2 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling MIR PF02815.19 KDO34388.1 - 6.3e-13 49.0 0.2 1.2e-11 44.8 0.2 2.4 1 1 0 1 1 1 1 MIR domain PDZ PF00595.24 KDO34389.1 - 0.0001 22.6 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain UBA PF00627.31 KDO34389.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain PDZ_6 PF17820.1 KDO34389.1 - 0.02 14.7 0.0 0.061 13.2 0.0 1.9 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 KDO34389.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain SPX PF03105.19 KDO34389.1 - 1.8 8.4 9.4 2.6 7.9 9.4 1.2 1 0 0 1 1 1 0 SPX domain CCT PF06203.14 KDO34390.1 - 4.9e-14 52.1 11.3 9.7e-14 51.1 11.3 1.5 1 0 0 1 1 1 1 CCT motif Asp1 PF16993.5 KDO34390.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 LRR_8 PF13855.6 KDO34391.1 - 0.0069 16.1 8.0 0.0076 16.0 4.3 2.8 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO34391.1 - 0.017 15.6 3.4 0.062 13.8 2.2 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO34391.1 - 0.071 13.7 1.8 29 5.7 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 KDO34391.1 - 0.36 11.0 6.6 12 6.2 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat ABC_tran PF00005.27 KDO34392.1 - 3.4e-48 163.6 0.0 3.4e-28 98.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO34392.1 - 5.2e-44 150.9 32.9 8.7e-28 97.7 9.0 3.3 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO34392.1 - 1.1e-06 28.2 5.8 0.0075 15.7 2.2 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO34392.1 - 6e-06 26.7 0.1 0.0086 16.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO34392.1 - 2.7e-05 24.2 0.5 0.048 13.7 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO34392.1 - 6.3e-05 22.6 0.4 0.13 12.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO34392.1 - 8.1e-05 22.6 0.2 0.54 10.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 KDO34392.1 - 0.0048 16.1 0.3 0.83 8.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KDO34392.1 - 0.0072 16.7 0.1 1.4 9.3 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_21 PF13304.6 KDO34392.1 - 0.017 15.0 1.3 4.5 7.0 0.3 3.4 2 2 2 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KDO34392.1 - 0.017 14.9 1.0 4.3 7.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DEAD PF00270.29 KDO34392.1 - 0.021 14.6 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KDO34392.1 - 0.033 13.7 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KDO34392.1 - 0.034 14.2 1.6 0.93 9.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KDO34392.1 - 0.061 13.8 0.1 2.9 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO34392.1 - 0.077 12.3 0.1 13 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KDO34392.1 - 0.09 12.8 3.5 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KDO34392.1 - 0.094 12.9 0.6 4.2 7.6 0.1 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KDO34392.1 - 0.12 12.6 3.3 12 6.2 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO34392.1 - 0.13 11.8 1.0 6.6 6.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 KDO34392.1 - 0.2 10.7 1.7 4.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KDO34392.1 - 0.52 9.6 2.2 10 5.3 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin ABC_membrane PF00664.23 KDO34395.1 - 3.9e-49 167.8 40.2 2.8e-25 89.5 18.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO34395.1 - 7.6e-40 136.6 0.6 8.4e-17 62.0 0.0 3.6 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 KDO34395.1 - 1.8e-06 27.6 6.4 0.0032 16.9 0.3 4.0 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO34395.1 - 3.5e-06 27.5 0.2 0.0085 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO34395.1 - 1.7e-05 24.9 0.0 0.033 14.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO34395.1 - 4.4e-05 23.1 0.5 0.13 12.0 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO34395.1 - 0.00023 21.1 1.9 0.58 10.0 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase IstB_IS21 PF01695.17 KDO34395.1 - 0.007 16.1 1.1 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO34395.1 - 0.0071 16.7 0.1 1.4 9.4 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_21 PF13304.6 KDO34395.1 - 0.019 14.8 1.1 6.3 6.5 0.2 3.4 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KDO34395.1 - 0.025 14.1 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KDO34395.1 - 0.033 14.3 1.6 0.92 9.6 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 KDO34395.1 - 0.044 12.9 2.4 0.81 8.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KDO34395.1 - 0.048 13.7 2.7 2.3 8.2 0.2 2.5 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 KDO34395.1 - 0.049 12.9 0.6 11 5.2 0.1 2.5 2 1 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 KDO34395.1 - 0.057 12.7 0.4 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KDO34395.1 - 0.059 13.9 0.1 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KDO34395.1 - 0.061 12.7 0.2 11 5.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KDO34395.1 - 0.067 13.5 2.8 12 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KDO34395.1 - 0.083 13.1 0.2 5.1 7.3 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KDO34395.1 - 0.13 11.9 0.9 5.8 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 KDO34395.1 - 0.17 11.7 1.2 3.6 7.4 0.2 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 KDO34395.1 - 0.18 10.8 1.8 5.2 6.0 0.0 3.0 2 1 0 3 3 3 0 Type II/IV secretion system protein AAA_18 PF13238.6 KDO34395.1 - 0.19 12.3 0.0 3.7 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KDO34395.1 - 0.23 11.1 0.3 12 5.5 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 KDO34395.1 - 1.4 8.7 3.1 23 4.7 2.0 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase dCMP_cyt_deam_1 PF00383.23 KDO34396.1 - 2.7e-28 97.8 0.6 1.3e-27 95.6 0.0 2.3 3 0 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KDO34396.1 - 2.8e-15 56.3 0.0 3.8e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 MafB19-like deaminase APOBEC4_like PF18774.1 KDO34396.1 - 0.035 14.0 0.2 0.095 12.6 0.1 1.8 2 0 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase Gln-synt_C-ter PF18318.1 KDO34396.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain SNAD4 PF18750.1 KDO34396.1 - 0.064 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KDO34396.1 - 0.084 13.0 0.2 0.22 11.7 0.2 1.7 1 0 0 1 1 1 0 APOBEC3 Ank_2 PF12796.7 KDO34399.1 - 1.3e-10 41.7 9.2 0.0045 17.5 0.1 5.3 2 1 5 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34399.1 - 7.9e-08 32.7 6.7 0.21 12.2 0.3 6.6 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34399.1 - 0.041 14.4 5.6 1.6e+02 3.4 0.0 6.7 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KDO34399.1 - 0.12 12.8 9.0 3.7 8.0 0.8 6.1 5 3 2 7 7 7 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34400.1 - 6e-13 49.2 2.3 2.4e-06 28.0 0.3 4.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34400.1 - 3.8e-08 33.7 7.6 0.0018 18.8 0.1 5.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34400.1 - 4.2e-08 33.3 7.5 0.14 12.5 0.0 5.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34400.1 - 8.3e-06 25.8 4.0 3.3 8.6 0.0 6.7 8 0 0 8 8 8 1 Ankyrin repeat DUF2534 PF10749.9 KDO34400.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) Ank_2 PF12796.7 KDO34401.1 - 4.6e-17 62.4 2.8 8.6e-05 23.1 0.0 4.7 3 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34401.1 - 8.8e-17 61.2 9.0 0.011 16.3 0.0 7.6 6 1 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34401.1 - 5.4e-09 36.1 7.5 3 8.3 0.0 8.4 6 2 3 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34401.1 - 1.5e-07 31.1 4.8 1.1 10.1 0.0 8.5 12 0 0 12 12 12 2 Ankyrin repeat Ank PF00023.30 KDO34401.1 - 0.19 12.2 0.6 67 4.2 0.0 4.9 6 1 1 7 7 7 0 Ankyrin repeat Abhydrolase_1 PF00561.20 KDO34404.1 - 1.3e-10 41.4 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO34404.1 - 3.7e-05 23.1 0.0 0.00018 20.9 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO34404.1 - 0.00034 21.3 13.2 0.011 16.4 13.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family ABC_membrane PF00664.23 KDO34405.1 - 2.4e-49 168.4 35.1 5.2e-27 95.2 17.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO34405.1 - 7.5e-37 126.9 0.0 4.8e-28 98.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO34405.1 - 4.7e-06 26.2 5.0 0.0027 17.2 0.3 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO34405.1 - 8.7e-06 26.2 0.8 0.012 16.0 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO34405.1 - 2e-05 24.6 0.3 0.047 13.8 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO34405.1 - 4.3e-05 23.2 0.3 0.13 12.0 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO34405.1 - 0.00013 21.9 0.3 0.61 10.0 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 KDO34405.1 - 0.00089 19.6 0.0 0.15 12.4 0.0 2.9 3 0 0 3 3 3 1 RNA helicase DUF815 PF05673.13 KDO34405.1 - 0.0067 15.6 1.1 0.69 9.0 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DEAD PF00270.29 KDO34405.1 - 0.011 15.6 0.4 0.11 12.2 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 KDO34405.1 - 0.013 15.2 0.4 4.2 7.1 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 KDO34405.1 - 0.033 13.7 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KDO34405.1 - 0.052 14.0 0.1 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO34405.1 - 0.054 13.6 1.5 0.91 9.6 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KDO34405.1 - 0.059 12.7 0.2 11 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 KDO34405.1 - 0.085 13.1 1.5 4.1 7.7 0.1 3.5 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KDO34405.1 - 0.089 12.4 1.5 4.3 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KDO34405.1 - 0.097 12.5 1.7 4.2 7.1 0.3 3.4 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KDO34405.1 - 0.12 11.4 1.2 5.1 6.1 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KDO34405.1 - 0.13 12.3 6.1 2.4 8.2 0.1 3.2 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.9 KDO34405.1 - 0.14 11.9 0.7 29 4.4 0.0 3.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KDO34405.1 - 0.16 12.3 3.6 13 6.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain IQ PF00612.27 KDO34406.1 - 1.5e-11 43.0 29.8 0.0067 16.1 2.0 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif TFIIA PF03153.13 KDO34406.1 - 7.1 6.5 6.5 36 4.2 5.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_4 PF12799.7 KDO34407.1 - 1.9e-22 78.9 20.8 6.5e-10 39.1 0.5 4.7 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO34407.1 - 8.4e-17 61.2 0.1 6.8e-12 45.2 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KDO34407.1 - 5.6e-10 38.8 12.2 9.6e-05 22.1 0.7 3.4 1 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KDO34407.1 - 0.002 18.1 1.2 7.5 6.9 0.1 4.0 3 0 0 3 3 3 1 Leucine Rich repeat T6PP_N PF18572.1 KDO34407.1 - 0.0051 16.6 0.4 0.011 15.6 0.4 1.5 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain TBCA PF02970.16 KDO34407.1 - 0.43 10.9 6.0 0.31 11.4 0.2 2.7 2 1 0 2 2 2 0 Tubulin binding cofactor A DUF1722 PF08349.11 KDO34407.1 - 0.59 10.4 4.0 4.7 7.5 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) PAP2_C PF14360.6 KDO34408.1 - 2.2e-08 34.5 4.7 2.2e-08 34.5 4.7 2.3 2 1 1 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KDO34408.1 - 0.0015 18.3 3.2 0.0015 18.3 3.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KDO34408.1 - 0.0054 16.4 10.4 0.0054 16.4 10.4 2.5 2 1 0 2 2 2 1 PAP2 superfamily PPR_long PF17177.4 KDO34409.1 - 1.4e-07 31.1 1.3 1.2e-06 28.1 1.1 2.6 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KDO34409.1 - 3e-07 30.5 0.3 0.045 14.0 0.0 4.1 3 1 2 5 5 5 2 PPR repeat family PPR PF01535.20 KDO34409.1 - 6.8e-06 26.0 0.0 0.15 12.4 0.0 4.4 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 KDO34409.1 - 1.9e-05 24.7 0.0 0.0013 18.7 0.0 2.6 1 1 2 3 3 3 2 Pentatricopeptide repeat domain TPR_19 PF14559.6 KDO34409.1 - 0.00047 20.6 6.6 0.16 12.5 1.7 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34409.1 - 0.013 15.6 0.9 1.3 9.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4611 PF15387.6 KDO34409.1 - 0.036 14.3 4.2 0.066 13.4 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PPR_1 PF12854.7 KDO34409.1 - 0.081 12.6 0.0 24 4.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat Cwf_Cwc_15 PF04889.12 KDO34409.1 - 3.1 7.5 7.1 4.7 6.9 7.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PrsW-protease PF13367.6 KDO34410.1 - 0.52 9.7 2.0 3 7.3 0.1 2.5 3 0 0 3 3 3 0 PrsW family intramembrane metalloprotease EF-hand_4 PF12763.7 KDO34412.1 - 6.9e-19 67.7 0.0 5.9e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KDO34412.1 - 5e-08 33.3 0.1 1.7e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO34412.1 - 8.1e-08 31.6 0.0 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KDO34412.1 - 4.5e-07 29.0 0.0 0.0024 17.3 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KDO34412.1 - 7.2e-05 22.1 0.0 0.028 13.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KDO34412.1 - 0.037 13.9 0.2 3.6 7.5 0.1 2.6 1 1 1 2 2 2 0 EF-hand domain pair DUF1707 PF08044.11 KDO34412.1 - 0.082 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Pkinase PF00069.25 KDO34413.1 - 3.3e-63 213.5 0.0 4.9e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34413.1 - 9.7e-43 146.3 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 KDO34413.1 - 5.8e-38 130.8 0.0 7.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 KDO34413.1 - 5.5e-07 29.2 0.0 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO34413.1 - 2.3e-05 23.4 0.0 7.2e-05 21.7 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO34413.1 - 7.2e-05 22.2 0.1 0.00017 21.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FliJ PF02050.16 KDO34413.1 - 0.25 11.6 4.1 0.5 10.6 4.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.12 KDO34413.1 - 0.67 10.0 8.8 2.4 8.2 8.8 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.6 KDO34413.1 - 0.96 9.6 12.9 3.8 7.7 4.1 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RNase_HII PF01351.18 KDO34414.1 - 1.4e-39 136.1 0.0 1.4e-39 136.1 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease HII Mucin-like PF16058.5 KDO34415.1 - 0.092 12.8 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Mucin-like COPI_assoc PF08507.10 KDO34417.1 - 1.3e-16 60.8 26.0 1e-09 38.5 4.6 2.3 2 0 0 2 2 2 2 COPI associated protein EF-hand_7 PF13499.6 KDO34417.1 - 3.3e-15 56.3 2.5 1.8e-07 31.5 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO34417.1 - 2.6e-14 51.8 0.5 0.027 14.4 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 KDO34417.1 - 1.9e-11 42.7 0.9 0.0055 16.2 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KDO34417.1 - 2.2e-08 33.2 1.5 0.31 10.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KDO34417.1 - 4.5e-05 23.2 4.9 0.013 15.3 0.2 3.4 4 0 0 4 4 4 2 EF-hand domain pair MgtE_N PF03448.17 KDO34417.1 - 0.00013 22.5 0.8 0.18 12.4 0.4 3.1 2 0 0 2 2 2 2 MgtE intracellular N domain TetR_C_33 PF13305.6 KDO34417.1 - 0.017 15.9 2.5 0.3 11.9 0.0 3.8 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Cg6151-P PF10233.9 KDO34417.1 - 0.018 15.4 3.6 0.018 15.4 3.6 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P EF-hand_10 PF14788.6 KDO34417.1 - 0.032 14.1 0.0 10 6.1 0.0 3.1 3 0 0 3 3 3 0 EF hand Pro_isomerase PF00160.21 KDO34419.1 - 9.5e-46 155.9 0.0 1.1e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF773 PF05600.12 KDO34420.1 - 1.2e-100 337.6 0.0 5.8e-99 332.1 0.0 2.0 1 1 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Hydrolase_4 PF12146.8 KDO34420.1 - 0.11 11.8 0.4 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TMF_DNA_bd PF12329.8 KDO34420.1 - 0.16 12.0 0.6 35 4.5 0.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KDO34420.1 - 2 8.5 6.1 1.1 9.3 0.8 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding AA_kinase PF00696.28 KDO34422.1 - 2.2e-39 135.5 2.4 3.5e-39 134.8 2.4 1.3 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 KDO34422.1 - 1.9e-11 43.2 0.5 3.6e-07 29.1 0.1 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.16 KDO34424.1 - 4.6e-09 35.7 24.9 4.6e-09 35.7 24.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily HhH-GPD PF00730.25 KDO34426.1 - 1.2e-22 80.4 0.0 2.2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KDO34426.1 - 5.2e-09 35.5 0.2 2.2e-08 33.6 0.0 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KDO34426.1 - 0.0021 18.6 0.0 0.24 12.1 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 KDO34426.1 - 0.028 14.7 5.0 0.054 13.8 5.0 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Translat_reg PF01818.17 KDO34426.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator PDZ_6 PF17820.1 KDO34427.1 - 0.0043 16.9 0.1 1.5 8.7 0.0 2.9 2 1 0 2 2 2 2 PDZ domain FPN1 PF06963.12 KDO34428.1 - 2.5e-21 75.8 1.4 2.5e-21 75.8 1.4 2.0 2 0 0 2 2 2 1 Ferroportin1 (FPN1) RRM PF10378.9 KDO34428.1 - 0.051 13.3 0.2 0.95 9.2 0.1 2.3 2 0 0 2 2 2 0 Putative RRM domain Glycos_transf_1 PF00534.20 KDO34429.1 - 4.3e-35 120.8 0.0 6.4e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO34429.1 - 5.2e-20 72.3 0.1 9.2e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KDO34429.1 - 5e-13 49.4 0.1 1.1e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KDO34429.1 - 1.2e-06 29.1 0.2 1.2e-06 29.1 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KDO34429.1 - 9.6e-06 25.9 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 bact-PGI_C PF10432.9 KDO34429.1 - 0.1 12.6 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Alpha_kinase PF02816.18 KDO34430.1 - 7.4e-56 189.2 0.0 1.1e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 KDO34430.1 - 6.3e-06 25.8 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 KDO34430.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G FeS_assembly_P PF01883.19 KDO34431.1 - 1.5e-13 50.7 0.0 4e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein VBS PF08913.10 KDO34432.1 - 0.08 13.4 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Vinculin Binding Site DUF1400 PF07176.11 KDO34432.1 - 0.098 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) LOR PF04525.12 KDO34434.1 - 1.6e-08 34.3 0.0 0.00076 19.1 0.0 2.6 3 0 0 3 3 3 2 LURP-one-related LOR PF04525.12 KDO34435.1 - 1.6e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 LURP-one-related LOR PF04525.12 KDO34436.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 LURP-one-related Rho_GDI PF02115.17 KDO34437.1 - 1.4e-41 142.4 0.0 1.7e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF1681 PF07933.14 KDO34438.1 - 8.1e-39 132.7 0.0 1e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Kinesin PF00225.23 KDO34439.1 - 6e-74 248.9 0.0 7.5e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO34439.1 - 1.6e-14 54.1 0.0 2.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 KDO34439.1 - 0.0075 16.0 3.6 0.034 13.8 0.0 2.8 2 2 0 2 2 2 1 AAA domain DUF87 PF01935.17 KDO34439.1 - 0.2 11.7 1.1 0.31 11.1 0.2 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain MFS_1 PF07690.16 KDO34440.1 - 5.6e-26 91.3 32.9 5.6e-26 91.3 32.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO34440.1 - 2.4e-25 88.9 14.8 1.4e-08 33.5 0.9 3.7 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family RVT_1 PF00078.27 KDO34440.1 - 3.8e-13 49.5 0.0 6e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.24 KDO34440.1 - 1.8e-10 40.3 20.5 6e-09 35.3 20.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO34441.1 - 3.7e-24 85.3 36.9 3.7e-24 85.3 36.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO34441.1 - 1.2e-21 76.7 9.4 4.2e-08 31.9 0.3 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO34441.1 - 5.9e-05 22.1 12.4 5.9e-05 22.1 12.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter GRDP-like PF07173.12 KDO34442.1 - 2.6e-16 60.5 0.4 5.7e-16 59.4 0.4 1.5 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like CDC24_OB3 PF17244.2 KDO34442.1 - 0.077 12.7 0.6 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 MFS_1 PF07690.16 KDO34443.1 - 3.6e-28 98.5 35.9 3.6e-28 98.5 35.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO34443.1 - 2.9e-24 85.3 9.9 2.1e-17 62.6 1.7 4.0 2 1 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO34443.1 - 5.6e-15 55.2 19.5 1.1e-14 54.2 19.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2754 PF10953.8 KDO34443.1 - 8.4 6.7 8.5 0.76 10.1 1.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2754) MFS_1 PF07690.16 KDO34444.1 - 4.6e-30 104.7 27.9 4.6e-30 104.7 27.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO34444.1 - 8.1e-21 73.9 17.4 4.4e-17 61.6 2.0 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO34444.1 - 3.3e-17 62.5 5.2 7.2e-17 61.4 5.2 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KDO34445.1 - 7.9e-29 100.3 16.0 1.3e-19 70.0 0.7 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KDO34445.1 - 2.3e-27 95.8 29.9 2.3e-27 95.8 29.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO34445.1 - 5.5e-11 42.0 20.9 3e-10 39.6 20.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KDO34446.1 - 1.8e-31 109.0 16.1 2.5e-21 75.6 0.3 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KDO34446.1 - 5.8e-31 107.7 28.6 5.8e-31 107.7 28.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KDO34446.1 - 8.1e-12 44.7 24.1 3e-11 42.9 24.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4748 PF15932.5 KDO34446.1 - 0.0056 16.4 0.4 0.016 14.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) PUCC PF03209.15 KDO34446.1 - 0.049 12.6 18.0 0.011 14.8 2.3 2.3 2 0 0 2 2 2 0 PUCC protein PsbL PF02419.17 KDO34446.1 - 0.4 10.7 7.1 4.4 7.4 0.5 3.3 3 0 0 3 3 3 0 PsbL protein DUF2614 PF11023.8 KDO34446.1 - 2.1 8.5 13.8 0.051 13.7 5.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain Myosin_head PF00063.21 KDO34447.1 - 8.6e-208 691.8 0.0 5.4e-207 689.2 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 KDO34447.1 - 3.5e-14 52.7 12.5 8.8e-14 51.4 12.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 KDO34447.1 - 1.1e-07 30.9 42.5 0.032 14.0 5.6 6.4 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_16 PF13191.6 KDO34447.1 - 0.021 15.2 0.0 0.021 15.2 0.0 3.2 3 1 1 4 4 4 0 AAA ATPase domain AAA_lid_6 PF17866.1 KDO34447.1 - 0.082 13.1 0.0 0.55 10.5 0.0 2.5 1 0 0 1 1 1 0 AAA lid domain DUF1319 PF07028.11 KDO34447.1 - 0.16 12.2 5.0 0.19 12.0 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Myosin_N PF02736.19 KDO34447.1 - 0.16 11.8 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Zeta_toxin PF06414.12 KDO34447.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 KDO34447.1 - 0.34 11.4 1.8 40 4.6 1.7 2.5 2 0 0 2 2 2 0 AAA domain Med26 PF08711.11 KDO34448.1 - 4.8e-05 23.3 2.6 6.7e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 KDO34448.1 - 0.0056 16.6 4.3 0.0097 15.8 4.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KDO34448.1 - 0.024 14.7 5.2 0.041 13.9 5.2 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 KDO34448.1 - 0.44 11.1 3.9 0.87 10.2 3.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ntox14 PF15522.6 KDO34450.1 - 0.36 10.2 2.3 0.83 9.0 1.8 1.8 1 1 1 2 2 2 0 Novel toxin 14 HTH_24 PF13412.6 KDO34452.1 - 0.23 11.0 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_membrane PF00664.23 KDO34456.1 - 6e-27 95.0 18.7 7.9e-27 94.6 18.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region WD40 PF00400.32 KDO34457.1 - 2e-19 69.6 6.0 1.5e-06 28.8 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO34457.1 - 5.1e-07 29.0 3.1 0.14 11.1 0.0 3.9 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KDO34457.1 - 1.7e-06 28.2 0.0 6.5 7.1 0.0 5.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KDO34457.1 - 5.3e-06 25.4 0.0 0.0064 15.3 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.12 KDO34457.1 - 0.0087 16.0 3.1 0.52 10.3 0.1 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Rubis-subs-bind PF09273.11 KDO34458.1 - 1.2e-19 71.3 0.2 2e-19 70.6 0.2 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KDO34458.1 - 1.1e-05 25.9 0.0 2.7e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 SET domain ABC_membrane PF00664.23 KDO34459.1 - 2.2e-39 135.8 32.9 3.8e-27 95.6 4.2 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO34459.1 - 8.5e-39 133.2 1.2 4.9e-19 69.2 0.0 3.4 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 KDO34459.1 - 2.9e-07 30.1 3.1 0.019 14.4 0.2 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO34459.1 - 8.5e-06 25.8 0.1 0.014 15.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO34459.1 - 2e-05 24.6 0.1 0.049 13.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KDO34459.1 - 2.1e-05 25.0 0.4 0.068 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KDO34459.1 - 0.00034 20.3 0.3 0.95 9.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO34459.1 - 0.0011 19.3 4.3 3.4 7.9 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_21 PF13304.6 KDO34459.1 - 0.0017 18.2 0.1 1.2 8.9 0.0 3.5 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KDO34459.1 - 0.0044 17.4 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 KDO34459.1 - 0.0052 16.0 0.2 0.57 9.3 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KDO34459.1 - 0.0066 16.2 1.5 0.66 9.7 0.3 2.9 2 1 0 2 2 2 1 IstB-like ATP binding protein Dynamin_N PF00350.23 KDO34459.1 - 0.015 15.4 0.2 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 KDO34459.1 - 0.019 15.5 0.2 0.54 10.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO34459.1 - 0.02 15.3 0.4 4.6 7.7 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO34459.1 - 0.041 13.5 1.2 1.5 8.4 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 KDO34459.1 - 0.064 12.8 2.5 6.9 6.2 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KDO34459.1 - 0.073 12.7 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain YscO-like PF16789.5 KDO34459.1 - 0.094 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 YscO-like protein Roc PF08477.13 KDO34459.1 - 0.12 12.6 0.3 5.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KDO34459.1 - 0.14 12.1 0.4 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KDO34459.1 - 0.16 11.6 0.8 20 4.7 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KDO34459.1 - 0.23 11.5 1.1 0.6 10.2 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain DUF5321 PF17254.2 KDO34459.1 - 0.26 10.7 1.8 0.23 10.9 0.3 1.6 2 0 0 2 2 1 0 Family of unknown function (DUF5321) AAA_30 PF13604.6 KDO34459.1 - 0.38 10.4 4.7 36 4.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 KDO34460.1 - 4.9e-13 49.2 10.8 7.3e-13 48.6 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KDO34460.1 - 2.4e-09 36.8 5.7 4.5e-09 35.9 5.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KDO34460.1 - 4.8e-09 35.9 11.3 7.7e-09 35.3 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO34460.1 - 1.1e-06 28.9 10.7 2.4e-06 27.7 10.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO34460.1 - 8.7e-06 25.5 9.4 1.3e-05 24.9 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO34460.1 - 0.00039 20.3 7.6 0.00057 19.8 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO34460.1 - 0.00043 20.1 6.2 0.00065 19.5 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO34460.1 - 0.0011 19.0 11.9 0.0019 18.2 11.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KDO34460.1 - 0.0011 19.0 3.0 0.0019 18.2 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KDO34460.1 - 0.052 13.5 4.8 0.2 11.6 2.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HEAT_2 PF13646.6 KDO34460.1 - 0.069 13.6 1.7 0.16 12.4 1.7 1.6 1 0 0 1 1 1 0 HEAT repeats WAC_Acf1_DNA_bd PF10537.9 KDO34460.1 - 0.22 12.1 0.2 25 5.4 0.2 2.2 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal zf-C3H2C3 PF17122.5 KDO34460.1 - 0.24 11.4 9.8 0.21 11.6 5.4 2.4 2 0 0 2 2 2 0 Zinc-finger Rad50_zn_hook PF04423.14 KDO34460.1 - 0.25 11.2 3.3 9.2 6.2 0.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Nse PF11789.8 KDO34460.1 - 0.29 11.0 3.4 0.53 10.1 3.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KDO34460.1 - 0.43 10.3 6.0 0.86 9.3 6.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KDO34460.1 - 4 7.3 6.5 11 5.9 6.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SYS1 PF09801.9 KDO34461.1 - 3.3e-39 134.3 0.3 3.8e-39 134.1 0.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MFS_2 PF13347.6 KDO34461.1 - 0.028 13.0 0.0 0.032 12.8 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein Kei1 PF08552.11 KDO34461.1 - 0.25 11.2 2.7 0.33 10.8 2.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 F-box-like PF12937.7 KDO34462.1 - 9.5e-05 22.2 1.7 0.0004 20.2 1.7 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KDO34462.1 - 0.023 14.6 1.0 0.078 12.9 1.0 1.9 1 0 0 1 1 1 0 F-box domain APC1_C PF18122.1 KDO34462.1 - 0.36 10.8 3.3 0.25 11.3 0.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain zf-C3HC4 PF00097.25 KDO34463.1 - 2.8e-08 33.5 10.8 4.1e-08 33.0 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO34463.1 - 2.8e-08 33.5 10.3 4e-08 33.0 10.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO34463.1 - 4e-08 33.5 9.2 6e-08 32.9 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KDO34463.1 - 6.3e-08 32.4 8.9 8.8e-08 31.9 8.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO34463.1 - 1e-07 31.8 6.2 3.4e-07 30.2 6.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO34463.1 - 2.2e-07 30.7 8.8 3.4e-07 30.1 8.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO34463.1 - 1.2e-06 28.3 8.8 1.1e-05 25.2 9.6 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 KDO34463.1 - 2e-06 27.5 0.6 0.023 14.5 0.0 2.3 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-Nse PF11789.8 KDO34463.1 - 8.9e-06 25.4 6.4 1.5e-05 24.7 6.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KDO34463.1 - 6.7e-05 23.0 11.0 0.00011 22.3 11.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KDO34463.1 - 0.0013 19.0 9.0 0.0044 17.3 9.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KDO34463.1 - 0.0079 16.0 7.0 0.19 11.6 2.3 2.2 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KDO34463.1 - 0.0098 15.5 3.6 0.0098 15.5 3.6 2.1 1 1 1 2 2 2 1 P-11 zinc finger zf-RING_6 PF14835.6 KDO34463.1 - 0.021 14.7 1.9 0.034 14.0 1.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3088 PF11287.8 KDO34463.1 - 0.23 11.2 2.6 0.42 10.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3088) zinc-ribbons_6 PF07191.12 KDO34463.1 - 0.62 10.1 6.6 1.6 8.8 6.5 1.7 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 KDO34463.1 - 1.4 9.0 6.8 5.9 7.0 6.3 2.0 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.21 KDO34463.1 - 1.5 9.0 6.4 14 5.9 6.6 2.2 1 1 1 2 2 2 0 FYVE zinc finger DUF676 PF05057.14 KDO34464.1 - 2e-36 125.5 0.0 3.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KDO34464.1 - 2.6e-06 27.3 0.0 8.8e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KDO34464.1 - 0.0001 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KDO34464.1 - 0.00049 20.8 0.0 0.00073 20.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 KDO34464.1 - 0.02 14.1 0.0 0.059 12.5 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KDO34464.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KDO34464.1 - 0.032 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PfkB PF00294.24 KDO34465.1 - 6.3e-23 81.5 0.0 9.1e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UEV PF05743.13 KDO34467.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 UEV domain Mito_carr PF00153.27 KDO34468.1 - 2.5e-50 168.4 1.1 7.2e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC_membrane PF00664.23 KDO34469.1 - 1.4e-84 284.0 34.1 1.2e-46 159.6 12.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO34469.1 - 1.7e-53 180.8 0.0 1.1e-29 103.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO34469.1 - 2e-07 30.7 5.1 0.051 13.0 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 KDO34469.1 - 8.6e-07 28.2 1.5 0.0024 16.9 0.2 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KDO34469.1 - 3.2e-06 27.2 1.8 0.054 13.6 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO34469.1 - 1.2e-05 25.0 0.9 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO34469.1 - 0.00017 21.6 0.1 0.46 10.4 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KDO34469.1 - 0.00053 20.1 2.4 0.06 13.4 0.4 2.4 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KDO34469.1 - 0.00056 20.3 0.1 0.49 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KDO34469.1 - 0.0013 18.5 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.17 KDO34469.1 - 0.0016 18.6 2.3 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KDO34469.1 - 0.0032 16.4 1.3 1.6 7.5 0.2 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 KDO34469.1 - 0.0034 17.9 0.3 3.6 8.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KDO34469.1 - 0.012 15.5 1.1 0.57 9.9 0.0 2.9 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KDO34469.1 - 0.022 13.8 0.2 3.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KDO34469.1 - 0.036 13.4 1.9 2 7.7 0.3 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KDO34469.1 - 0.042 14.0 0.2 0.73 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO34469.1 - 0.047 13.3 0.2 5.2 6.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO34469.1 - 0.055 13.2 3.4 4.1 7.1 0.1 3.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KDO34469.1 - 0.062 12.5 0.7 4.7 6.3 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_18 PF13238.6 KDO34469.1 - 0.09 13.3 1.3 10 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KDO34469.1 - 0.097 12.7 0.1 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 KDO34469.1 - 0.1 12.5 0.1 5 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 KDO34469.1 - 0.1 12.9 3.7 1.6 9.0 0.3 3.0 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KDO34469.1 - 0.1 12.2 2.1 1.1 8.9 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KDO34469.1 - 0.11 12.7 0.5 6.4 7.0 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KDO34469.1 - 0.12 11.6 1.3 3.5 6.8 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KDO34469.1 - 0.17 11.6 1.6 15 5.3 0.5 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KDO34469.1 - 0.22 11.4 3.6 2.3 8.1 0.2 3.2 3 0 0 3 3 3 0 NACHT domain DEAD PF00270.29 KDO34470.1 - 7.4e-49 165.9 0.1 1.9e-48 164.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO34470.1 - 2.9e-31 108.1 0.0 3.3e-28 98.3 0.0 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO34470.1 - 0.00034 20.6 0.4 0.0084 16.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KDO34470.1 - 0.0088 15.3 0.0 0.0088 15.3 0.0 2.2 3 0 0 3 3 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KDO34470.1 - 0.0096 15.3 0.0 0.0096 15.3 0.0 3.1 2 1 0 2 2 1 1 U3-containing 90S pre-ribosomal complex subunit CCER1 PF15482.6 KDO34470.1 - 0.14 12.0 2.4 0.32 10.9 2.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 UTP25 PF06862.12 KDO34470.1 - 0.15 10.8 0.0 0.53 9.0 0.0 1.8 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 KDO34470.1 - 0.18 12.1 1.7 7.5 6.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain Protocadherin PF08374.11 KDO34470.1 - 1.5 8.7 7.0 3 7.8 7.0 1.4 1 0 0 1 1 1 0 Protocadherin DDRGK PF09756.9 KDO34470.1 - 1.9 8.1 16.8 0.73 9.4 14.2 1.7 2 0 0 2 2 2 0 DDRGK domain DUF4770 PF15994.5 KDO34470.1 - 3.9 7.7 8.1 8.6 6.6 8.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 KDO34470.1 - 7.3 6.6 6.5 13 5.8 6.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pkinase_Tyr PF07714.17 KDO34472.1 - 1.2e-20 73.9 0.3 3.6e-18 65.8 1.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KDO34472.1 - 4.5e-13 49.2 0.3 8.3e-12 45.0 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Topoisom_I PF01028.20 KDO34473.1 - 1.2e-92 309.4 3.0 2.8e-92 308.1 3.0 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KDO34473.1 - 1.1e-83 279.9 0.2 1.1e-83 279.9 0.2 3.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KDO34473.1 - 9.6e-31 105.5 0.5 3.6e-30 103.7 0.5 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase_Tyr PF07714.17 KDO34474.1 - 7.2e-53 179.5 0.0 1.1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34474.1 - 1.3e-35 123.0 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO34474.1 - 0.0047 15.8 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO34474.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF737 PF05300.11 KDO34474.1 - 0.13 12.6 1.2 0.22 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) APG6_N PF17675.1 KDO34474.1 - 0.17 12.4 5.3 0.3 11.6 5.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SecD_SecF PF02355.16 KDO34474.1 - 5.2 6.4 6.1 0.4 10.0 0.8 1.8 2 0 0 2 2 2 0 Protein export membrane protein GHMP_kinases_N PF00288.26 KDO34475.1 - 1.7e-12 47.4 0.3 4.4e-12 46.1 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KDO34475.1 - 2.2e-08 34.3 0.1 4.8e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal APG9 PF04109.16 KDO34475.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 FlgT_N PF16548.5 KDO34475.1 - 0.17 12.5 0.3 3.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain DUF1298 PF06974.13 KDO34476.1 - 5.5e-29 101.0 0.0 9.6e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KDO34476.1 - 1.7e-22 80.5 0.4 5.5e-18 65.7 0.2 2.3 1 1 1 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KDO34476.1 - 0.00013 20.8 0.3 0.00018 20.3 0.3 1.1 1 0 0 1 1 1 1 Condensation domain Endopep_inhib PF16800.5 KDO34476.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor DUF4107 PF13389.6 KDO34477.1 - 0.89 9.7 2.1 2.5 8.3 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Pap_E4 PF02711.14 KDO34477.1 - 8.3 7.4 11.9 20 6.2 1.0 3.5 2 1 1 3 3 3 0 E4 protein FAM194 PF14977.6 KDO34478.1 - 4.6e-23 81.6 0.0 7.6e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 FAM194 protein Thioredoxin PF00085.20 KDO34478.1 - 2.5e-05 24.2 0.0 0.00041 20.3 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 KDO34478.1 - 0.00013 21.8 0.2 0.0018 18.3 0.2 2.5 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KDO34478.1 - 0.0063 16.9 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain zinc_ribbon_10 PF10058.9 KDO34478.1 - 0.036 13.8 0.3 0.094 12.5 0.3 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF3173 PF11372.8 KDO34478.1 - 0.068 13.1 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) DUF4971 PF16341.5 KDO34478.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) FYVE PF01363.21 KDO34480.1 - 1.4e-13 50.8 13.8 1.4e-13 50.8 13.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger FIST PF08495.10 KDO34480.1 - 6.6e-11 42.5 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 FIST N domain FYVE_2 PF02318.16 KDO34480.1 - 0.00099 19.3 4.5 0.0023 18.1 4.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger FIST_C PF10442.9 KDO34480.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FIST C domain IBR PF01485.21 KDO34480.1 - 0.7 10.2 6.8 1.9 8.8 6.8 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KDO34480.1 - 1.2 9.6 12.1 2.9 8.3 12.1 1.7 1 0 0 1 1 1 0 Ring finger domain PDEase_I PF00233.19 KDO34481.1 - 4.4e-70 236.1 3.0 6e-70 235.7 3.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Glyco_hydro_18 PF00704.28 KDO34482.1 - 5.6e-14 52.6 0.0 1.7e-13 51.0 0.0 1.5 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 KDO34482.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 WD40 PF00400.32 KDO34483.1 - 8.7e-36 121.3 24.1 0.0013 19.5 0.0 10.3 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34483.1 - 1.4e-17 63.8 1.7 0.31 11.3 0.0 7.6 4 1 3 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KDO34483.1 - 0.00075 17.9 0.4 0.081 11.2 0.0 2.9 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz TauE PF01925.19 KDO34484.1 - 1.9e-21 76.8 25.0 3.6e-12 46.4 1.7 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE TauE PF01925.19 KDO34485.1 - 1.8e-24 86.7 29.4 4.5e-13 49.4 3.6 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE CcmD PF04995.14 KDO34485.1 - 0.29 11.2 5.1 0.18 11.9 1.5 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Pkinase_Tyr PF07714.17 KDO34486.1 - 5.2e-57 193.1 0.0 7.1e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34486.1 - 6.8e-37 127.3 0.0 9.9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO34486.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO34486.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KDO34487.1 - 1.4e-56 191.6 0.0 1.8e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34487.1 - 6.8e-36 124.0 0.0 9e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO34487.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO34487.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KDO34487.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TMEM247 PF15444.6 KDO34487.1 - 0.17 11.9 0.2 0.27 11.3 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Haspin_kinase PF12330.8 KDO34487.1 - 0.31 9.9 0.0 0.47 9.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KDO34488.1 - 7.9e-37 126.9 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34488.1 - 1.5e-24 86.8 0.0 2.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KDO34488.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KDO34488.1 - 0.066 12.6 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO34488.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TRAM1 PF08390.11 KDO34488.1 - 8.1 6.2 7.0 0.47 10.1 1.0 2.1 2 0 0 2 2 2 0 TRAM1-like protein Pkinase_Tyr PF07714.17 KDO34489.1 - 3.9e-55 186.9 0.0 5.2e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34489.1 - 1.4e-39 136.0 0.0 2.1e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO34489.1 - 0.0079 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO34489.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KDO34489.1 - 0.21 10.3 0.0 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Sas10_Utp3 PF04000.15 KDO34490.1 - 4.5e-15 56.1 0.2 1.9e-14 54.0 0.2 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Trypsin_2 PF13365.6 KDO34492.1 - 3.5e-17 63.7 0.6 5.9e-17 63.0 0.6 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO34492.1 - 2e-10 40.9 1.3 2.7e-10 40.4 1.3 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KDO34492.1 - 0.0047 15.7 2.6 0.86 8.2 0.1 2.8 2 1 1 3 3 3 2 Peptidase S46 Peptidase_S29 PF02907.15 KDO34492.1 - 0.026 14.2 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease RNB PF00773.19 KDO34493.1 - 1.3e-87 294.2 0.0 1.8e-87 293.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KDO34493.1 - 1.8e-16 59.9 0.0 4.9e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 KDO34493.1 - 1.6e-08 34.4 0.0 4.8e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 KDO34493.1 - 4.3e-08 33.4 0.0 1.3e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Pkinase_Tyr PF07714.17 KDO34494.1 - 2.4e-55 187.6 0.0 2.8e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34494.1 - 3.1e-40 138.2 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO34494.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KDO34494.1 - 0.02 13.7 0.0 0.04 12.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KDO34494.1 - 0.06 13.3 1.0 8.7 6.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO34494.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Mito_carr PF00153.27 KDO34495.1 - 2.2e-58 194.2 1.0 1e-18 67.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Carb_anhydrase PF00194.21 KDO34496.1 - 5.2e-32 111.4 0.0 1.1e-31 110.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Polyketide_cyc PF03364.20 KDO34498.1 - 2.9e-24 85.7 0.2 5.6e-24 84.8 0.2 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EF-hand_1 PF00036.32 KDO34498.1 - 5.1e-08 31.9 0.1 0.0011 18.4 0.0 3.5 3 0 0 3 3 3 2 EF hand Polyketide_cyc2 PF10604.9 KDO34498.1 - 1.5e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EF-hand_6 PF13405.6 KDO34498.1 - 6e-05 22.6 0.1 0.002 17.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KDO34498.1 - 0.00012 21.4 0.0 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KDO34498.1 - 0.0019 18.6 0.6 0.023 15.2 0.1 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO34498.1 - 0.0033 17.2 0.1 0.14 12.1 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain pair DUF4913 PF16259.5 KDO34498.1 - 0.078 13.1 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Trypsin_2 PF13365.6 KDO34499.1 - 1.3e-15 58.6 0.1 3.4e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO34499.1 - 0.0043 16.9 1.6 0.0043 16.9 1.6 2.3 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 KDO34499.1 - 0.006 15.3 2.2 0.73 8.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KDO34499.1 - 0.15 11.2 2.8 10 5.2 0.0 3.2 3 0 0 3 3 3 0 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.6 KDO34500.1 - 3e-16 60.6 0.4 3e-16 60.6 0.4 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KDO34500.1 - 4.2e-05 23.5 1.4 7.5e-05 22.6 1.4 1.3 1 0 0 1 1 1 1 Trypsin MHYT PF03707.16 KDO34500.1 - 1 9.6 4.8 1.1 9.4 0.2 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Trypsin_2 PF13365.6 KDO34501.1 - 1.3e-05 26.1 0.2 2e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Arif-1 PF06770.11 KDO34503.1 - 0.032 13.9 0.0 0.032 13.9 0.0 1.0 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Pkinase PF00069.25 KDO34505.1 - 2.3e-65 220.6 0.0 3.1e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34505.1 - 3.3e-24 85.6 0.0 4.4e-23 81.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO34505.1 - 0.026 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO34505.1 - 0.17 11.2 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO34505.1 - 0.19 11.6 0.1 5.6 6.8 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family LIN52 PF10044.9 KDO34509.1 - 0.0002 22.0 0.1 0.0003 21.4 0.1 1.3 1 0 0 1 1 1 1 Retinal tissue protein HMA PF00403.26 KDO34510.1 - 0.00011 22.5 0.4 0.00077 19.9 0.0 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain RAB3GAP2_N PF14655.6 KDO34510.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-RING_11 PF17123.5 KDO34511.1 - 1.6e-07 30.9 3.8 2.7e-07 30.2 2.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger ubiquitin PF00240.23 KDO34511.1 - 8.7e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-RING_2 PF13639.6 KDO34511.1 - 2.2e-06 27.9 10.9 2.2e-06 27.9 10.9 2.9 3 1 1 4 4 3 1 Ring finger domain zf-rbx1 PF12678.7 KDO34511.1 - 0.00054 20.2 7.6 0.00054 20.2 7.6 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KDO34511.1 - 0.0034 17.2 10.0 0.0034 17.2 10.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO34511.1 - 0.016 15.1 9.7 0.016 15.1 9.7 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Cys_rich_CPXG PF14255.6 KDO34511.1 - 0.13 12.1 0.2 0.13 12.1 0.2 2.9 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-C3HC4_3 PF13920.6 KDO34511.1 - 0.33 10.8 17.6 1.5 8.8 9.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO34511.1 - 0.56 10.1 21.4 0.15 11.9 11.7 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KDO34511.1 - 1.8 8.8 8.8 4.9 7.4 8.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KDO34511.1 - 2.3 8.4 16.9 0.29 11.2 5.9 2.9 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KDO34511.1 - 2.5 7.9 19.7 0.49 10.2 8.1 3.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KDO34511.1 - 3.1 7.5 15.3 0.05 13.2 6.8 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KDO34511.1 - 3.1 8.0 11.6 1.4 9.1 4.1 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 KDO34511.1 - 3.7 7.8 16.7 0.22 11.7 5.3 2.3 1 1 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KDO34511.1 - 6.1 7.2 16.3 0.55 10.5 6.1 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KDO34512.1 - 2.7e-05 24.4 15.0 2.7e-05 24.4 15.0 3.0 3 1 0 3 3 3 1 Ring finger domain ubiquitin PF00240.23 KDO34512.1 - 0.00098 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-C3HC4 PF00097.25 KDO34512.1 - 0.035 14.0 18.9 0.066 13.1 14.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO34512.1 - 2.3 8.2 17.8 29 4.6 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KDO34512.1 - 2.4 8.0 8.0 6.6 6.6 8.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KDO34512.1 - 2.5 8.5 18.9 4.6 7.6 13.5 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain Asn_synthase PF00733.21 KDO34513.1 - 2.1e-68 231.6 0.0 2.6e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KDO34513.1 - 3.4e-37 127.1 0.1 9.7e-37 125.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KDO34513.1 - 1.4e-33 116.0 0.1 4.4e-33 114.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KDO34513.1 - 0.0006 19.3 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein Pkinase_Tyr PF07714.17 KDO34514.1 - 1.3e-56 191.8 0.0 1.7e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34514.1 - 2.2e-38 132.2 0.0 3.8e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KDO34514.1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B_6 PF16661.5 KDO34515.1 - 1.5e-10 40.8 0.0 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KDO34515.1 - 6.8e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 KDO34515.1 - 0.018 15.0 0.0 0.8 9.6 0.0 3.2 3 1 0 3 3 3 0 Beta-lactamase superfamily domain Sec1 PF00995.23 KDO34516.1 - 2.8e-61 208.5 0.0 4e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Ank_2 PF12796.7 KDO34516.1 - 1.8e-15 57.3 9.1 3.7e-10 40.3 1.7 4.2 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34516.1 - 6.2e-13 49.0 11.3 2.4e-06 28.0 0.7 5.3 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34516.1 - 1.8e-08 34.0 7.0 2.6 8.9 0.1 7.1 4 1 2 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KDO34516.1 - 8.1e-08 32.4 9.2 0.82 10.1 0.2 6.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KDO34516.1 - 0.0016 18.8 15.1 4.7 7.8 0.4 6.4 2 1 3 5 5 5 3 Ankyrin repeat FeoB_associated PF12669.7 KDO34518.1 - 0.077 13.4 0.3 0.12 12.8 0.3 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein adh_short PF00106.25 KDO34519.1 - 1e-35 123.0 0.3 1.3e-35 122.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO34519.1 - 2.7e-22 79.5 2.1 3.8e-22 79.0 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO34519.1 - 8.3e-12 45.4 2.4 1.7e-11 44.4 2.4 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KDO34519.1 - 0.028 14.0 0.3 0.042 13.4 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.8 KDO34519.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PX PF00787.24 KDO34520.1 - 4e-07 30.0 0.6 2e-05 24.5 0.0 3.0 3 0 0 3 3 3 1 PX domain Succ_CoA_lig PF13607.6 KDO34520.1 - 3.5 7.4 6.1 0.35 10.7 0.2 2.4 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain N6_N4_Mtase PF01555.18 KDO34520.1 - 6.2 6.5 6.3 1.2 8.8 0.2 2.5 2 1 0 3 3 3 0 DNA methylase PspA_IM30 PF04012.12 KDO34521.1 - 0.00026 20.6 15.6 0.001 18.7 15.6 1.7 1 1 0 1 1 1 1 PspA/IM30 family KASH_CCD PF14662.6 KDO34521.1 - 0.011 15.5 16.5 0.022 14.6 16.5 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FAS_I_H PF18314.1 KDO34521.1 - 0.016 14.9 1.0 0.016 14.9 1.0 2.1 1 1 2 3 3 3 0 Fatty acid synthase type I helical domain DUF1515 PF07439.11 KDO34521.1 - 0.052 13.6 6.6 0.033 14.2 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) PEARLI-4 PF05278.12 KDO34521.1 - 0.094 12.3 6.2 0.17 11.5 6.2 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc7 PF08317.11 KDO34521.1 - 0.1 11.5 14.2 0.11 11.4 10.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GvpG PF05120.12 KDO34521.1 - 0.15 12.1 8.2 0.098 12.7 3.5 2.7 2 2 0 2 2 2 0 Gas vesicle protein G Sec2p PF06428.11 KDO34521.1 - 0.16 12.0 14.1 0.21 11.6 3.0 3.4 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p UPF0242 PF06785.11 KDO34521.1 - 0.19 11.9 17.2 32 4.6 17.1 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 KDO34521.1 - 0.2 11.7 5.2 3.2 7.8 2.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Leu_zip PF15294.6 KDO34521.1 - 0.21 11.1 16.6 0.54 9.7 15.8 1.8 1 1 1 2 2 2 0 Leucine zipper Exonuc_VII_L PF02601.15 KDO34521.1 - 0.21 11.1 6.1 0.26 10.8 6.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 KDO34521.1 - 0.21 11.7 16.0 0.36 10.9 14.6 2.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KDO34521.1 - 0.23 10.8 10.2 0.29 10.5 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KDO34521.1 - 0.26 10.3 9.7 0.45 9.6 9.7 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 KDO34521.1 - 0.27 11.3 17.3 0.16 12.1 8.4 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF148 PF02520.17 KDO34521.1 - 0.35 11.0 9.1 0.31 11.1 6.3 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF148 PKcGMP_CC PF16808.5 KDO34521.1 - 0.37 10.7 0.1 0.37 10.7 0.1 4.4 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Prominin PF05478.11 KDO34521.1 - 0.54 8.1 4.5 0.81 7.6 4.5 1.2 1 0 0 1 1 1 0 Prominin bZIP_1 PF00170.21 KDO34521.1 - 0.65 10.1 18.6 0.49 10.5 3.2 3.9 3 1 1 4 4 4 0 bZIP transcription factor V_ATPase_I_N PF18670.1 KDO34521.1 - 0.66 10.4 4.2 0.37 11.2 0.3 2.3 2 1 1 3 3 3 0 V-type ATPase subunit I, N-terminal domain Cep57_CLD_2 PF14197.6 KDO34521.1 - 0.75 9.9 18.3 0.05 13.7 8.6 2.9 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 Apolipoprotein PF01442.18 KDO34521.1 - 0.8 9.6 17.9 8 6.3 17.9 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMPIT PF07851.13 KDO34521.1 - 0.91 8.7 6.7 0.36 10.0 4.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.18 KDO34521.1 - 1 8.6 8.9 1.1 8.6 8.1 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ACCA PF03255.14 KDO34521.1 - 1 9.2 10.0 8.9 6.2 0.0 3.2 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2203 PF09969.9 KDO34521.1 - 1.2 9.9 8.3 0.77 10.5 1.6 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 KDO34521.1 - 1.2 9.7 7.1 1.3 9.7 4.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V-ATPase_G_2 PF16999.5 KDO34521.1 - 1.3 9.5 14.1 0.23 11.9 3.5 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4061 PF13270.6 KDO34521.1 - 2 8.8 11.0 6.3 7.2 8.9 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) FAM76 PF16046.5 KDO34521.1 - 2.1 7.6 13.9 14 4.9 13.9 2.0 1 1 0 1 1 1 0 FAM76 protein DUF883 PF05957.13 KDO34521.1 - 4.9 7.8 10.3 0.8 10.3 0.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Med9 PF07544.13 KDO34521.1 - 5.9 7.1 12.2 8.8 6.5 5.2 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 KDO34521.1 - 9.2 6.4 9.9 30 4.8 7.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PH PF00169.29 KDO34522.1 - 1.3e-17 64.2 0.0 3.3e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PTEN_C2 PF10409.9 KDO34522.1 - 7.4e-11 41.9 0.3 7.8e-10 38.6 0.3 2.3 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 KDO34522.1 - 8.8e-10 39.0 0.1 2.6e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain Y_phosphatase PF00102.27 KDO34522.1 - 6.9e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KDO34522.1 - 8.3e-06 25.9 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KDO34522.1 - 7.1e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KDO34522.1 - 0.0061 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 KDO34522.1 - 0.0088 15.6 0.3 0.028 14.0 0.3 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KDO34522.1 - 0.014 15.6 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate PH_3 PF14593.6 KDO34522.1 - 0.015 15.4 0.0 0.05 13.7 0.0 1.9 1 1 0 1 1 1 0 PH domain PH_8 PF15409.6 KDO34522.1 - 0.031 14.6 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Myotub-related PF06602.14 KDO34522.1 - 0.076 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain HSF_DNA-bind PF00447.17 KDO34523.1 - 4.1e-25 88.2 0.3 5.8e-25 87.7 0.3 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DNA_pol_B_exo2 PF10108.9 KDO34523.1 - 0.091 12.4 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pkinase_Tyr PF07714.17 KDO34524.1 - 2.2e-44 151.7 0.0 2.9e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34524.1 - 1.6e-35 122.8 0.0 2.3e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO34524.1 - 1.9e-05 24.7 3.2 0.03 14.2 0.1 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KDO34524.1 - 0.0024 17.3 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S14 PF00253.21 KDO34524.1 - 0.017 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e PIG-X PF08320.12 KDO34526.1 - 5.5e-29 101.6 1.0 3e-28 99.2 1.0 2.0 1 1 0 1 1 1 1 PIG-X / PBN1 TraW_N PF12477.8 KDO34526.1 - 0.94 9.5 6.1 20 5.3 5.6 3.1 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal adh_short PF00106.25 KDO34528.1 - 5.2e-45 153.3 4.6 7.3e-45 152.8 4.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO34528.1 - 1.2e-39 136.3 4.4 3.5e-39 134.7 4.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO34528.1 - 4.2e-16 59.4 2.0 5.9e-16 58.9 2.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KDO34528.1 - 0.0078 15.5 3.6 0.011 15.1 1.0 2.4 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KDO34528.1 - 0.013 15.4 1.5 0.024 14.5 1.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KDO34528.1 - 0.077 12.4 0.4 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_72 PF03198.14 KDO34529.1 - 5.6e-48 163.8 0.0 8.1e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KDO34529.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.6 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) CIAPIN1 PF05093.13 KDO34530.1 - 4.1e-16 59.3 17.2 1.5e-12 47.9 3.9 2.4 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SPT6_acidic PF14632.6 KDO34530.1 - 0.061 13.9 1.5 0.12 12.9 1.5 1.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 adh_short PF00106.25 KDO34531.1 - 1.3e-44 152.1 0.2 1.8e-44 151.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO34531.1 - 1.1e-25 90.6 0.2 1.6e-25 90.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO34531.1 - 8.4e-12 45.4 0.4 1.3e-11 44.7 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KDO34531.1 - 0.00077 19.9 0.2 0.0016 18.8 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KDO34531.1 - 0.0037 17.2 0.1 0.0055 16.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KDO34531.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KDO34531.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 KDO34531.1 - 0.018 14.6 1.2 0.035 13.7 1.2 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KDO34531.1 - 0.025 14.5 0.7 0.044 13.7 0.7 1.4 1 0 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KDO34531.1 - 0.04 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.27 KDO34531.1 - 0.13 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LRR_6 PF13516.6 KDO34532.1 - 3.6e-07 29.7 0.1 4.7 7.5 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat SET_assoc PF11767.8 KDO34532.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DEAD PF00270.29 KDO34533.1 - 3.1e-46 157.4 0.2 6.8e-46 156.2 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO34533.1 - 5.2e-23 81.5 0.0 2.9e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KDO34533.1 - 4.5e-17 62.0 0.8 2.8e-16 59.5 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KDO34533.1 - 6.2e-10 39.3 0.2 1.5e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF19 PF01579.18 KDO34533.1 - 0.028 14.2 1.5 0.088 12.6 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF19) Abhydrolase_1 PF00561.20 KDO34534.1 - 6.4e-16 58.8 0.2 4.8e-14 52.6 0.1 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO34534.1 - 2.3e-12 46.7 0.1 2.2e-11 43.5 0.1 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO34534.1 - 4.3e-07 30.7 0.3 4.3e-07 30.7 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 KDO34534.1 - 0.00082 18.2 0.0 0.0047 15.7 0.0 1.9 2 0 0 2 2 2 1 Ndr family FGAR-AT_N PF18076.1 KDO34535.1 - 0.042 13.8 0.9 14 5.7 0.0 2.7 1 1 2 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase N-terminal HycH PF07450.11 KDO34535.1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH DUF1917 PF08939.10 KDO34536.1 - 1e-18 68.2 0.0 7.2e-18 65.4 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) PDZ PF00595.24 KDO34537.1 - 1.3e-06 28.7 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KDO34537.1 - 4.1e-05 23.3 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain NAD_kinase PF01513.21 KDO34538.1 - 1.3e-61 208.4 0.0 2.3e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KDO34538.1 - 0.0029 17.2 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pox_A_type_inc PF04508.12 KDO34538.1 - 0.0096 15.7 0.1 0.029 14.2 0.1 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat PspA_IM30 PF04012.12 KDO34538.1 - 0.14 11.7 1.0 0.22 11.1 1.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family P_C10 PF14974.6 KDO34539.1 - 9.1e-19 67.5 1.1 1.4e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Protein C10 Ig_3 PF13927.6 KDO34539.1 - 2.6e-05 24.7 0.0 5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain WD40 PF00400.32 KDO34539.1 - 0.0012 19.6 1.1 0.035 15.0 0.2 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat IQ PF00612.27 KDO34539.1 - 0.0089 15.7 2.6 0.027 14.3 2.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zn_ribbon_SprT PF17283.2 KDO34539.1 - 0.018 15.0 3.9 0.041 13.8 3.9 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Ig_2 PF13895.6 KDO34539.1 - 0.025 14.9 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain TraI PF07057.11 KDO34539.1 - 0.039 14.1 0.7 0.085 13.0 0.7 1.5 1 0 0 1 1 1 0 DNA helicase TraI DUF3042 PF11240.8 KDO34540.1 - 0.93 9.6 3.0 1.6 8.8 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) PPE PF00823.19 KDO34541.1 - 0.46 10.6 7.4 0.96 9.5 2.4 2.6 2 1 1 3 3 3 0 PPE family Ank_4 PF13637.6 KDO34542.1 - 4.1e-51 170.7 24.5 1.1e-07 32.3 0.0 11.5 6 3 5 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34542.1 - 3.7e-44 148.2 34.6 0.00039 20.7 0.3 16.4 2 2 15 17 17 17 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34542.1 - 1e-43 147.8 16.5 3.3e-08 34.0 0.1 7.8 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO34542.1 - 3.4e-27 91.5 10.7 3.1 8.7 0.0 15.8 15 1 1 16 16 16 7 Ankyrin repeat Ank PF00023.30 KDO34542.1 - 5.5e-09 36.1 5.2 28 5.4 0.0 11.3 6 2 2 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 KDO34542.1 - 3.2e-07 30.2 1.6 3.5 7.6 0.0 8.9 9 2 2 11 11 11 1 Domain of unknown function (DUF5049) DUF1979 PF09322.10 KDO34542.1 - 0.0028 17.5 0.2 12 5.9 0.0 6.0 7 0 0 7 7 7 1 Domain of unknown function (DUF1979) Kinesin PF00225.23 KDO34544.1 - 4.2e-103 344.8 0.0 6.2e-103 344.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO34544.1 - 1.7e-22 80.0 0.0 4.6e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF3694 PF12473.8 KDO34544.1 - 5.8e-05 23.8 0.0 0.00021 22.0 0.0 2.1 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KDO34544.1 - 0.03 14.5 0.6 0.11 12.7 0.5 2.0 1 1 0 1 1 1 0 Kinesin-associated Epimerase PF01370.21 KDO34545.1 - 4.4e-32 111.5 0.1 5.8e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KDO34545.1 - 8.2e-24 84.2 0.8 5.5e-17 61.8 0.2 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KDO34545.1 - 1.8e-19 70.3 0.4 2.6e-19 69.8 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KDO34545.1 - 3.1e-19 69.1 0.0 4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KDO34545.1 - 2.6e-15 56.6 0.0 5.5e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KDO34545.1 - 3.4e-14 52.6 0.3 4.6e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KDO34545.1 - 1.8e-10 40.8 0.1 2.7e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KDO34545.1 - 4.9e-10 39.0 0.5 2.2e-09 36.9 0.5 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KDO34545.1 - 0.00025 21.0 0.3 0.00075 19.4 0.3 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KDO34545.1 - 0.00038 20.0 0.2 0.0027 17.2 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 KDO34545.1 - 0.00079 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain His_Phos_1 PF00300.22 KDO34546.1 - 4.5e-14 52.6 0.0 1.4e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 KDO34547.1 - 3.9e-16 59.3 0.0 1.3e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DnaJ_C PF01556.18 KDO34548.1 - 1.5e-30 106.2 0.0 2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO34548.1 - 5.7e-27 93.6 0.6 8.7e-27 93.0 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KDO34548.1 - 3.9e-14 52.8 17.4 6.2e-14 52.1 17.4 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KDO34548.1 - 5e-06 26.4 8.4 0.0017 18.3 0.6 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KDO34548.1 - 0.00084 19.3 7.7 0.19 11.8 0.7 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KDO34548.1 - 0.0092 16.0 9.3 0.015 15.3 9.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_10 PF16685.5 KDO34548.1 - 6.2 7.0 8.9 0.65 10.2 0.3 2.4 2 1 0 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 KDO34548.1 - 9.8 5.8 10.3 2.9 7.5 1.2 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Pirin PF02678.16 KDO34549.1 - 7.3e-26 90.3 0.0 2.1e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KDO34549.1 - 4.9e-25 87.9 0.0 3.3e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Peptidase_S10 PF00450.22 KDO34551.1 - 6.6e-102 342.0 0.0 8e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UBA PF00627.31 KDO34552.1 - 5.1e-29 99.8 13.8 1.6e-15 56.6 0.1 4.0 4 0 0 4 4 4 2 UBA/TS-N domain XPC-binding PF09280.11 KDO34552.1 - 9.4e-24 82.9 6.7 9.4e-24 82.9 6.7 3.4 2 1 1 3 3 2 1 XPC-binding domain ubiquitin PF00240.23 KDO34552.1 - 7.3e-23 80.1 1.1 1.5e-22 79.1 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KDO34552.1 - 0.0023 17.7 0.3 0.0053 16.6 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KDO34552.1 - 0.0031 17.2 4.6 1.5 8.6 0.0 3.3 4 0 0 4 4 4 2 CUE domain DUF2407 PF10302.9 KDO34552.1 - 0.01 16.4 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KDO34552.1 - 0.016 15.6 0.2 0.032 14.6 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1421 PF07223.11 KDO34552.1 - 0.065 13.1 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Ubiquitin_2 PF14560.6 KDO34552.1 - 0.092 13.2 0.1 0.3 11.6 0.1 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KDO34552.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DnaB_2 PF07261.11 KDO34552.1 - 0.18 11.6 0.0 15 5.4 0.0 2.9 3 0 0 3 3 3 0 Replication initiation and membrane attachment UBA_3 PF09288.10 KDO34552.1 - 0.18 11.7 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3135 PF11333.8 KDO34552.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.9 2 2 0 2 2 1 0 Protein of unknown function (DUF3135) FliJ PF02050.16 KDO34552.1 - 0.44 10.8 6.5 1.1 9.5 6.5 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3617 PF12276.8 KDO34552.1 - 0.5 10.7 12.3 0.23 11.8 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3617) DUF3306 PF11748.8 KDO34552.1 - 6.6 7.6 9.3 0.78 10.6 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Prismane PF03063.20 KDO34553.1 - 1.8e-99 333.8 0.0 2.3e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 KDO34553.1 - 1.9e-38 132.2 0.0 3.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KDO34553.1 - 3.5e-25 88.9 0.0 7.6e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KDO34553.1 - 1.1e-05 26.1 0.0 3.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ThuA PF06283.11 KDO34553.1 - 0.076 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Trehalose utilisation IRK_C PF17655.1 KDO34554.1 - 4.1e-28 98.1 0.1 1.6e-13 50.6 0.0 2.5 3 0 0 3 3 3 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KDO34554.1 - 7.1e-07 29.1 6.0 2.8e-06 27.2 6.0 1.9 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KDO34554.1 - 0.00059 19.8 1.9 0.0012 18.8 1.9 1.5 1 0 0 1 1 1 1 Ion channel Pirin PF02678.16 KDO34556.1 - 6.2e-15 55.1 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Pirin GST_C_3 PF14497.6 KDO34556.1 - 1.2e-11 44.7 0.1 1.8e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO34556.1 - 6.8e-08 32.7 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KDO34556.1 - 3.4e-07 30.4 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO34556.1 - 0.0033 17.4 0.1 0.0083 16.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO34556.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KDO34556.1 - 0.081 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Amidase PF01425.21 KDO34557.1 - 2.2e-91 307.1 1.1 7e-91 305.4 1.1 1.7 1 1 0 1 1 1 1 Amidase Glyco_hydro81C PF17652.1 KDO34558.1 - 1.2e-117 393.1 0.6 1.7e-117 392.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KDO34558.1 - 4e-49 167.5 0.1 5.3e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Borrelia_P83 PF05262.11 KDO34560.1 - 0.0014 17.2 9.5 0.0014 17.2 9.5 1.4 2 0 0 2 2 2 1 Borrelia P83/100 protein U1snRNP70_N PF12220.8 KDO34560.1 - 0.0032 18.1 1.9 0.0032 18.1 1.9 2.6 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal YbjQ_1 PF01906.17 KDO34561.1 - 1.7e-23 83.2 0.5 2.4e-23 82.7 0.5 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF3605 PF12239.8 KDO34564.1 - 0.0037 17.6 2.4 0.0087 16.4 2.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) MS_channel PF00924.18 KDO34565.1 - 9.6e-21 74.3 0.3 1.4e-19 70.5 0.3 2.2 1 1 0 1 1 1 1 Mechanosensitive ion channel DUF4271 PF14093.6 KDO34565.1 - 0.093 12.6 7.8 0.14 12.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) FerA PF08165.11 KDO34565.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 FerA (NUC095) domain Topoisom_bac PF01131.20 KDO34566.1 - 1.5e-103 347.0 0.0 3.2e-103 345.9 0.0 1.5 2 0 0 2 2 2 1 DNA topoisomerase zf-GRF PF06839.12 KDO34566.1 - 1.1e-41 140.7 20.4 7.7e-17 61.1 1.4 4.1 3 0 0 3 3 3 3 GRF zinc finger Toprim PF01751.22 KDO34566.1 - 2.1e-17 63.2 0.0 5.4e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Toprim domain p450 PF00067.22 KDO34567.1 - 1.2e-25 90.2 0.0 2.8e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Ribosomal_L20 PF00453.18 KDO34568.1 - 3.4e-41 139.7 1.6 3.8e-41 139.5 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 SMC_ScpA PF02616.14 KDO34568.1 - 0.045 13.7 0.2 0.055 13.4 0.2 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA SPA PF08616.10 KDO34569.1 - 7.6e-07 29.1 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KDO34569.1 - 1.2e-06 27.5 0.0 1.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 KDO34569.1 - 0.008 16.1 0.1 4.5 7.2 0.0 2.9 3 0 0 3 3 3 2 DENN (AEX-3) domain Afi1 PF07792.12 KDO34569.1 - 0.029 14.9 0.4 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_C15 PF01470.17 KDO34570.1 - 7.7e-18 65.4 0.0 9.2e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Peptidase_C15 PF01470.17 KDO34571.1 - 4.5e-26 92.3 0.0 5.4e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase HECT_2 PF09814.9 KDO34572.1 - 4e-38 131.3 0.0 9.5e-38 130.0 0.0 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SCAB_CC PF16712.5 KDO34572.1 - 0.019 14.8 0.3 0.056 13.3 0.5 1.6 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein YcgR PF07317.12 KDO34572.1 - 0.02 14.8 0.1 0.072 13.0 0.1 2.0 1 1 0 1 1 1 0 Flagellar regulator YcgR She9_MDM33 PF05546.11 KDO34572.1 - 0.23 11.2 2.5 0.15 11.9 0.4 1.6 2 0 0 2 2 2 0 She9 / Mdm33 family PSCyt3 PF07627.11 KDO34572.1 - 0.29 11.4 1.7 2.3 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) Yippee-Mis18 PF03226.14 KDO34572.1 - 1.5 9.1 4.5 35 4.7 0.0 2.8 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MT PF12777.7 KDO34573.1 - 0.04 12.9 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Peptidase_C1 PF00112.23 KDO34574.1 - 1.6e-60 204.9 2.8 1.9e-60 204.7 2.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO34574.1 - 0.00038 19.3 2.8 0.0083 15.0 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Acyl-CoA_dh_M PF02770.19 KDO34575.1 - 6.7e-18 64.7 0.1 1.4e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KDO34575.1 - 1.1e-12 47.9 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 KDO34575.1 - 9.4e-07 29.2 2.8 1.3e-05 25.4 0.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KDO34575.1 - 0.021 15.4 0.0 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Pkinase PF00069.25 KDO34576.1 - 1.7e-70 237.4 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34576.1 - 2.9e-33 115.3 0.0 1.7e-32 112.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34576.1 - 3.7e-07 29.8 0.0 5.5e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KDO34576.1 - 8.7e-05 21.6 0.2 0.00016 20.8 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KDO34576.1 - 0.0039 17.1 0.3 2.1 8.2 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO34576.1 - 0.056 12.2 0.0 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase FeoB_N PF02421.18 KDO34576.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B FTA2 PF13095.6 KDO34576.1 - 0.071 12.7 0.2 14 5.2 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KDO34576.1 - 0.085 12.2 0.4 0.15 11.4 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_A_exo1 PF01612.20 KDO34579.1 - 9.6e-41 139.4 1.2 1.7e-40 138.6 1.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 KDO34579.1 - 1.4e-13 50.6 0.0 3.5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 KDO34579.1 - 1.3e-08 35.4 0.2 4.1e-08 33.8 0.2 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain PXPV PF12778.7 KDO34579.1 - 5 7.1 13.8 10 6.1 9.8 2.6 1 1 1 2 2 2 0 PXPV repeat (3 copies) PWI PF01480.17 KDO34580.1 - 1.6e-08 34.7 0.0 4.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PWI domain zf-U11-48K PF05253.12 KDO34580.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger F_bP_aldolase PF01116.20 KDO34581.1 - 1.4e-89 300.3 0.1 1.7e-89 300.0 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LRR_4 PF12799.7 KDO34582.1 - 8.4e-19 67.4 7.0 1.9e-05 24.9 0.2 3.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO34582.1 - 6.4e-17 61.6 4.6 1.5e-15 57.1 4.8 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KDO34582.1 - 1.7e-09 37.3 10.0 0.0033 17.1 8.6 3.5 2 2 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KDO34582.1 - 0.0091 16.0 1.9 4.1 7.7 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KDO34582.1 - 0.28 11.9 4.9 74 4.5 0.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat SAM_3 PF18016.1 KDO34582.1 - 1.4 8.8 5.1 15 5.5 0.3 3.4 2 1 2 4 4 4 0 SAM domain (Sterile alpha motif) Asn_synthase PF00733.21 KDO34583.1 - 2e-19 70.5 0.0 2.8e-17 63.4 0.2 2.0 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 KDO34583.1 - 0.0046 16.5 0.0 0.03 13.8 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DZR PF12773.7 KDO34583.1 - 0.032 14.2 1.5 0.097 12.7 1.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KDO34583.1 - 1.1 9.0 3.4 2.8 7.8 3.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Ysc84 PF04366.12 KDO34584.1 - 4.1e-35 120.3 0.2 8.2e-35 119.4 0.2 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator EF-hand_1 PF00036.32 KDO34585.1 - 1.6e-22 77.3 6.8 3e-07 29.5 0.8 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KDO34585.1 - 1.1e-18 67.4 2.9 7e-12 45.6 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO34585.1 - 1.6e-16 58.7 5.7 1.4e-05 24.6 0.0 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KDO34585.1 - 1.1e-14 54.0 4.6 5.7e-05 22.9 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KDO34585.1 - 1.3e-12 46.6 6.0 0.00017 20.9 0.7 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KDO34585.1 - 1.1e-07 32.0 0.1 3.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain eIF3g PF12353.8 KDO34586.1 - 2.2e-29 102.4 0.6 3.4e-29 101.8 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KDO34586.1 - 1.4e-18 66.4 0.0 2.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEBP_beta PF07404.11 KDO34588.1 - 0.61 9.4 2.0 1 8.7 2.0 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) AAA_16 PF13191.6 KDO34589.1 - 4e-06 27.3 0.1 1.3e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KDO34589.1 - 0.0066 16.4 0.2 0.014 15.3 0.2 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KDO34589.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KDO34589.1 - 0.033 14.6 0.0 0.051 14.0 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO34589.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CobU PF02283.16 KDO34589.1 - 0.13 11.9 0.1 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_14 PF13173.6 KDO34589.1 - 0.14 12.2 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Glyco_transf_20 PF00982.21 KDO34590.1 - 2.4e-98 329.9 0.0 1.4e-84 284.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KDO34590.1 - 1e-37 129.5 0.0 1.7e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KDO34590.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phospho_p8 PF10195.9 KDO34591.1 - 1.9 9.0 15.4 2.6 8.6 1.9 3.1 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 Choline_transpo PF04515.12 KDO34592.1 - 5.2e-80 269.1 32.2 5.2e-80 269.1 32.2 2.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter LisH PF08513.11 KDO34593.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 LisH RED_C PF07807.11 KDO34594.1 - 0.0071 16.8 0.7 0.018 15.5 0.7 1.7 1 0 0 1 1 1 1 RED-like protein C-terminal region Bot1p PF12298.8 KDO34594.1 - 0.0085 16.3 0.4 0.015 15.5 0.4 1.4 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Aminotran_3 PF00202.21 KDO34595.1 - 1e-114 383.4 0.0 1.2e-114 383.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KDO34595.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KDO34595.1 - 0.11 11.4 0.0 0.56 9.1 0.0 1.9 1 1 0 1 1 1 0 Aminotransferase class-V ATP-gua_PtransN PF02807.15 KDO34596.1 - 2.5e-25 88.6 0.0 3.6e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Cpn60_TCP1 PF00118.24 KDO34597.1 - 2.4e-153 511.3 0.1 2.7e-153 511.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2121 PF09894.9 KDO34597.1 - 0.019 14.5 0.1 0.05 13.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) Beta_helix_2 PF18835.1 KDO34597.1 - 0.15 11.9 0.1 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase ATP-gua_Ptrans PF00217.19 KDO34598.1 - 2.1e-73 246.3 0.0 2.7e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KDO34598.1 - 3.6e-26 91.3 0.0 6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4660 PF15559.6 KDO34599.1 - 0.037 14.3 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) DHHC PF01529.20 KDO34600.1 - 1.1e-34 119.4 12.0 1.1e-34 119.4 12.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase LCD1 PF09798.9 KDO34601.1 - 0.015 13.9 0.0 0.015 13.8 0.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SNARE PF05739.19 KDO34601.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 SNARE domain Sec20 PF03908.13 KDO34601.1 - 0.041 13.8 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 Sec20 Use1 PF09753.9 KDO34601.1 - 0.18 11.5 1.4 0.38 10.4 0.1 1.8 1 1 0 1 1 1 0 Membrane fusion protein Use1 Gelsolin PF00626.22 KDO34602.1 - 2e-90 296.8 0.0 1.4e-18 66.6 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 KDO34602.1 - 8.9e-16 57.7 1.1 1.7e-15 56.8 1.1 1.5 1 0 0 1 1 1 1 Villin headpiece domain Pkinase PF00069.25 KDO34603.1 - 1e-68 231.6 0.0 1.1e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34603.1 - 4.3e-35 121.3 0.0 5.3e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34603.1 - 2.2e-06 27.2 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rota_NSP4 PF01452.16 KDO34603.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Rotavirus non structural protein CENP-B_N PF04218.13 KDO34603.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain ATG16 PF08614.11 KDO34604.1 - 0.013 15.7 11.3 0.013 15.7 11.3 3.1 2 2 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3810 PF12725.7 KDO34604.1 - 0.11 11.8 1.3 0.22 10.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ESM4 PF15952.5 KDO34604.1 - 0.14 12.5 5.0 0.25 11.7 5.0 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family YjfB_motility PF14070.6 KDO34604.1 - 0.33 11.2 6.9 0.093 12.9 0.9 2.8 3 0 0 3 3 3 0 Putative motility protein MitMem_reg PF13012.6 KDO34604.1 - 1.2 9.5 7.6 0.85 10.1 4.4 2.3 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Fib_alpha PF08702.10 KDO34604.1 - 3.7 7.7 8.8 5.8 7.1 7.3 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 KDO34605.1 - 1.6e-56 188.8 41.3 4.7e-12 46.3 0.1 7.6 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34605.1 - 1.6e-33 114.3 17.6 4.1e-07 30.2 0.6 7.2 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO34605.1 - 4.1e-30 103.8 5.8 1.5e-05 25.4 0.0 8.0 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KDO34605.1 - 3.2e-26 90.6 27.1 0.00014 22.2 0.0 11.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 KDO34605.1 - 1.3e-23 80.5 17.2 0.014 15.9 0.0 12.6 12 0 0 12 12 12 6 Ankyrin repeat RIH_assoc PF08454.11 KDO34605.1 - 5.3e-14 51.9 0.0 2.3e-13 49.9 0.0 2.2 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 KDO34605.1 - 2.6e-06 26.8 0.0 6.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 KDO34605.1 - 0.00064 19.0 27.9 0.0019 17.5 27.9 1.9 1 0 0 1 1 1 1 Ion transport protein MIR PF02815.19 KDO34605.1 - 0.034 14.0 0.1 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 MIR domain Lebercilin PF15619.6 KDO34606.1 - 2.2e-08 34.0 30.8 2.2e-08 34.0 30.8 2.8 1 1 2 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Csm1_N PF18504.1 KDO34606.1 - 0.00086 19.6 3.5 0.00086 19.6 3.5 5.8 2 2 3 6 6 6 1 Csm1 N-terminal domain CEP63 PF17045.5 KDO34606.1 - 1.6 8.6 37.9 0.65 9.8 6.4 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Leu_zip PF15294.6 KDO34606.1 - 3.5 7.1 33.8 1.7 8.1 16.5 2.1 1 1 1 2 2 2 0 Leucine zipper Adaptin_binding PF10199.9 KDO34606.1 - 6.7 7.3 11.7 4.4e+02 1.5 11.6 2.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ATG16 PF08614.11 KDO34606.1 - 8.9 6.5 41.2 9.7 6.4 19.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) QWRF PF04484.12 KDO34607.1 - 0.00063 19.6 7.5 0.00086 19.1 7.5 1.1 1 0 0 1 1 1 1 QWRF family PcfK PF14058.6 KDO34608.1 - 0.028 14.7 5.8 0.075 13.3 5.8 1.7 1 0 0 1 1 1 0 PcfK-like protein DUF4710 PF15828.5 KDO34608.1 - 0.2 11.8 8.1 0.61 10.2 8.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Peptidase_S49_N PF08496.10 KDO34608.1 - 0.52 10.4 5.4 0.84 9.7 4.3 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal NST1 PF13945.6 KDO34608.1 - 0.68 10.0 11.6 0.15 12.1 3.6 2.8 3 0 0 3 3 3 0 Salt tolerance down-regulator Presenilin PF01080.17 KDO34608.1 - 2.4 6.8 5.5 7 5.3 4.1 2.1 2 0 0 2 2 2 0 Presenilin Aldo_ket_red PF00248.21 KDO34609.1 - 2.5e-39 135.3 0.0 2.7e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ACD PF16671.5 KDO34609.1 - 0.094 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Actin cross-linking domain HECT PF00632.25 KDO34610.1 - 7.8e-77 258.8 0.0 1.3e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 KDO34610.1 - 1.2e-05 24.5 2.2 2e-05 23.8 2.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KDO34610.1 - 0.041 13.3 0.4 0.1 12.0 0.4 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SUKH_5 PF14567.6 KDO34610.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall EF-hand_7 PF13499.6 KDO34611.1 - 4.7e-11 43.0 0.5 3.3e-06 27.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO34611.1 - 1.5e-08 33.9 0.1 0.0017 18.1 0.0 2.9 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KDO34611.1 - 1.6e-05 24.1 0.0 0.15 11.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KDO34611.1 - 0.0043 17.4 0.2 1 9.7 0.0 2.7 1 1 2 3 3 3 2 EF-hand domain EFhand_Ca_insen PF08726.10 KDO34611.1 - 0.026 14.6 1.6 0.13 12.4 0.1 2.4 2 1 0 2 2 2 0 Ca2+ insensitive EF hand TPR_1 PF00515.28 KDO34612.1 - 2.3e-07 30.3 0.0 0.0018 18.0 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO34612.1 - 3.9e-05 24.2 0.0 7.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34612.1 - 0.00028 20.8 0.0 0.98 9.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34612.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34612.1 - 0.013 15.9 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO34612.1 - 0.035 13.8 0.0 2.9 7.6 0.0 2.2 1 1 1 2 2 2 0 TPR repeat TPR_17 PF13431.6 KDO34612.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34612.1 - 0.075 13.9 0.0 3.3 8.8 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34612.1 - 0.089 13.0 0.0 20 5.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PX PF00787.24 KDO34613.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 PX domain Myb_DNA-binding PF00249.31 KDO34614.1 - 2.6e-31 107.5 3.5 4.4e-16 58.8 1.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KDO34614.1 - 4.6e-27 94.0 1.0 2.1e-18 66.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO34614.1 - 1.3e-08 34.6 0.5 0.00014 21.7 0.1 2.5 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KDO34614.1 - 9.2e-06 25.8 2.2 0.029 14.5 0.1 3.0 3 0 0 3 3 3 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KDO34614.1 - 0.0034 17.4 0.8 0.15 12.0 0.1 2.6 1 1 1 2 2 2 1 SLIDE AAA PF00004.29 KDO34615.1 - 5.7e-98 324.5 0.0 1.2e-47 161.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO34615.1 - 6.3e-25 86.7 10.4 4.2e-12 45.7 1.0 3.5 2 2 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KDO34615.1 - 1.7e-21 76.2 0.6 4.3e-21 74.9 0.3 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KDO34615.1 - 1e-14 54.6 0.0 3.5e-06 26.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 KDO34615.1 - 3.9e-14 52.2 0.0 9.1e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 KDO34615.1 - 3.3e-13 50.1 0.0 1.2e-06 28.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KDO34615.1 - 4.9e-12 46.6 3.5 0.00048 20.5 0.1 4.6 3 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KDO34615.1 - 2.7e-11 43.8 0.0 3.7e-05 23.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KDO34615.1 - 9.8e-11 41.8 0.1 2.2e-05 24.5 0.1 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO34615.1 - 1.5e-10 41.5 1.0 0.019 15.2 0.0 5.0 4 2 0 4 4 3 2 AAA domain TIP49 PF06068.13 KDO34615.1 - 2.6e-08 33.5 0.1 0.0013 18.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KDO34615.1 - 3.4e-08 33.6 0.0 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 KDO34615.1 - 7.8e-08 32.2 0.2 1.3e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KDO34615.1 - 5.3e-07 29.2 0.3 0.033 13.6 0.0 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KDO34615.1 - 6.1e-07 29.8 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KDO34615.1 - 7.4e-07 29.8 0.0 0.066 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KDO34615.1 - 3.6e-06 26.5 0.2 1.7 8.0 0.0 3.4 3 0 0 3 3 3 2 KaiC IstB_IS21 PF01695.17 KDO34615.1 - 3.7e-06 26.8 0.1 0.07 12.9 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KDO34615.1 - 4.4e-06 26.6 0.0 0.0057 16.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 KDO34615.1 - 5.2e-06 26.4 0.0 0.068 13.0 0.0 3.2 3 1 1 4 4 3 2 Bacterial dnaA protein ATPase_2 PF01637.18 KDO34615.1 - 7.1e-06 26.1 0.1 0.1 12.5 0.0 2.9 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KDO34615.1 - 1.2e-05 24.9 0.1 0.067 12.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KDO34615.1 - 1.8e-05 24.4 2.0 1.8 8.1 0.1 3.7 2 2 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KDO34615.1 - 1.9e-05 25.1 0.0 0.12 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KDO34615.1 - 3.5e-05 23.8 0.1 0.26 11.3 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KDO34615.1 - 4e-05 23.9 0.1 0.16 12.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KDO34615.1 - 5.1e-05 23.3 0.0 0.81 9.6 0.0 3.6 3 1 0 4 4 4 2 NACHT domain AAA_24 PF13479.6 KDO34615.1 - 5.5e-05 23.0 0.0 0.16 11.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KDO34615.1 - 9.6e-05 22.1 0.0 0.73 9.5 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KDO34615.1 - 0.00012 22.6 0.0 0.37 11.3 0.0 3.2 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 KDO34615.1 - 0.00032 20.0 0.0 0.87 8.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Parvo_NS1 PF01057.17 KDO34615.1 - 0.00043 19.5 0.1 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KDO34615.1 - 0.00046 19.4 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 KDO34615.1 - 0.00078 19.6 0.0 0.56 10.3 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 KDO34615.1 - 0.001 19.2 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family ResIII PF04851.15 KDO34615.1 - 0.001 19.1 0.0 0.089 12.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KDO34615.1 - 0.0011 18.8 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KDO34615.1 - 0.0016 17.7 0.0 0.39 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 KDO34615.1 - 0.003 17.1 1.4 1.3 8.4 0.0 2.8 3 0 0 3 3 2 1 PhoH-like protein NTPase_1 PF03266.15 KDO34615.1 - 0.003 17.5 0.9 2.6 7.9 0.0 4.0 3 1 1 4 4 4 1 NTPase UFD1 PF03152.14 KDO34615.1 - 0.0053 16.2 0.0 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_11 PF13086.6 KDO34615.1 - 0.0057 16.5 0.3 5.5 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KDO34615.1 - 0.0083 15.4 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 KDO34615.1 - 0.0098 15.8 0.0 1.8 8.4 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 KDO34615.1 - 0.015 15.7 0.5 15 5.9 0.1 3.4 3 1 0 4 4 2 0 AAA domain AAA_30 PF13604.6 KDO34615.1 - 0.027 14.2 1.4 4.9 6.8 0.1 3.0 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 KDO34615.1 - 0.029 13.6 0.1 2.6 7.2 0.0 3.1 2 2 2 4 4 4 0 KAP family P-loop domain Zot PF05707.12 KDO34615.1 - 0.044 13.4 0.0 0.9 9.2 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 KDO34615.1 - 0.066 12.9 0.0 17 5.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 KDO34615.1 - 0.069 13.3 0.0 7.4 6.7 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 KDO34615.1 - 0.12 12.1 0.0 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 KDO34615.1 - 0.15 11.8 0.0 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.23 KDO34616.1 - 2.5e-64 217.7 0.4 3e-64 217.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KDO34616.1 - 3.7e-10 40.3 1.9 4.4e-06 27.1 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KDO34616.1 - 0.0014 19.2 0.6 0.039 14.6 0.1 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KDO34616.1 - 0.0038 17.0 0.1 0.026 14.3 0.2 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KDO34616.1 - 0.01 16.4 0.1 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF383 PF04063.14 KDO34617.1 - 1.5e-35 122.6 0.0 1.5e-35 122.6 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KDO34617.1 - 9.3e-19 67.0 0.2 9.3e-19 67.0 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF384) Neurochondrin PF05536.11 KDO34617.1 - 8.7e-06 24.4 1.4 0.0055 15.1 0.3 2.9 2 1 1 3 3 3 2 Neurochondrin HEAT PF02985.22 KDO34617.1 - 0.066 13.5 4.6 9.6 6.8 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.23 KDO34617.1 - 0.33 11.0 7.1 1.3 9.2 0.1 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Pirin_C PF05726.13 KDO34618.1 - 2.3e-25 89.0 0.0 2.2e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 KDO34618.1 - 1.1e-15 57.5 0.0 3.7e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Pirin IRK_C PF17655.1 KDO34619.1 - 1.4e-25 89.9 0.0 3e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KDO34619.1 - 1.2e-11 44.6 7.9 6.3e-11 42.3 7.9 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KDO34619.1 - 0.025 14.5 9.9 0.049 13.6 9.7 1.6 1 1 1 2 2 2 0 Ion channel Ion_trans PF00520.31 KDO34619.1 - 0.03 13.6 3.1 0.043 13.0 3.1 1.2 1 0 0 1 1 1 0 Ion transport protein RabGAP-TBC PF00566.18 KDO34620.1 - 1.6e-18 67.2 0.2 3.7e-18 66.0 0.2 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 KDO34620.1 - 8.5e-18 64.8 0.0 3e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO34620.1 - 0.025 15.0 0.0 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain V-ATPase_H_N PF03224.14 KDO34620.1 - 0.033 13.5 0.0 0.078 12.3 0.0 1.6 1 1 0 1 1 1 0 V-ATPase subunit H zf-P11 PF03854.14 KDO34620.1 - 0.23 11.1 2.3 0.2 11.3 0.4 1.9 2 0 0 2 2 2 0 P-11 zinc finger His_Phos_2 PF00328.22 KDO34621.1 - 5.4e-22 78.7 0.0 9.8e-22 77.8 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ank_2 PF12796.7 KDO34622.1 - 2.2e-85 281.3 23.9 4.3e-19 68.9 1.2 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KDO34622.1 - 7.7e-56 184.2 22.1 1.1e-05 25.7 0.3 11.1 10 1 1 11 11 11 10 Ankyrin repeat Ank_4 PF13637.6 KDO34622.1 - 1.3e-54 181.8 16.1 8.4e-10 39.0 0.0 8.5 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34622.1 - 4e-52 168.1 9.2 5.6e-05 23.2 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 KDO34622.1 - 1.5e-35 120.8 21.6 5.7e-06 26.5 0.0 8.8 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 KDO34622.1 - 0.0058 16.5 8.9 27 4.8 0.1 6.9 8 0 0 8 8 8 0 Superinfection immunity protein GATase_7 PF13537.6 KDO34622.1 - 0.022 14.7 0.0 37 4.2 0.0 4.7 5 1 1 6 6 6 0 Glutamine amidotransferase domain Pyridoxal_deC PF00282.19 KDO34622.1 - 0.033 12.9 0.2 5.1 5.7 0.0 3.9 4 1 1 5 5 5 0 Pyridoxal-dependent decarboxylase conserved domain T6SS-SciN PF12790.7 KDO34622.1 - 0.044 13.5 0.4 23 4.7 0.0 3.8 4 0 0 4 4 4 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 CEP44 PF15007.6 KDO34623.1 - 3.8e-32 111.1 0.2 5.8e-32 110.5 0.2 1.3 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 ABC_tran_CTD PF16326.5 KDO34623.1 - 0.063 13.5 0.3 0.37 11.1 0.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain HalX PF08663.10 KDO34623.1 - 0.14 12.5 0.5 2.4 8.6 0.1 2.5 1 1 1 2 2 2 0 HalX domain IQ PF00612.27 KDO34624.1 - 7.4e-26 87.5 119.9 0.001 18.6 0.3 17.6 18 0 0 18 18 18 14 IQ calmodulin-binding motif EF-hand_1 PF00036.32 KDO34624.1 - 8.2e-16 56.3 0.7 8.4e-07 28.1 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO34624.1 - 9.8e-13 48.4 0.8 9.8e-13 48.4 0.8 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KDO34624.1 - 6.5e-12 45.1 1.1 1.1e-11 44.3 0.3 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO34624.1 - 1.4e-11 43.4 0.2 6.2e-06 25.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO34624.1 - 1.6e-11 43.1 0.7 3.9e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 EF hand WW PF00397.26 KDO34624.1 - 3.1e-11 43.2 16.9 1e-06 28.7 3.7 2.5 2 0 0 2 2 2 2 WW domain EF-hand_9 PF14658.6 KDO34624.1 - 3.6e-05 24.0 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 KDO34624.1 - 0.00027 20.8 0.1 0.00085 19.2 0.1 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Nkap_C PF06047.11 KDO34625.1 - 7.8 6.7 13.0 84 3.4 9.6 3.1 2 1 1 3 3 3 0 NF-kappa-B-activating protein C-terminal domain Cellulase PF00150.18 KDO34626.1 - 2.2e-13 50.3 1.0 7e-13 48.6 1.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 KDO34626.1 - 0.0026 17.4 0.0 0.006 16.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.18 KDO34627.1 - 1.6e-12 47.5 1.2 8e-12 45.2 1.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 KDO34627.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core IGPD PF00475.18 KDO34628.1 - 1.8e-60 203.4 0.6 3.3e-60 202.6 0.6 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.6 KDO34628.1 - 2.9e-16 60.0 0.0 5.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KDO34628.1 - 4.7e-06 27.0 2.3 0.0029 17.9 0.0 3.0 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KDO34628.1 - 0.0012 18.8 1.0 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like DUF3168 PF11367.8 KDO34628.1 - 6.7 6.9 8.7 4.3 7.5 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF3168) WD40 PF00400.32 KDO34629.1 - 5.4e-36 122.0 34.8 1e-05 26.2 0.8 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34629.1 - 1.3e-07 31.9 1.9 0.0065 16.7 0.0 4.9 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KDO34629.1 - 0.00018 21.3 0.6 0.00043 20.1 0.6 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KDO34629.1 - 0.0003 19.6 2.9 0.059 12.0 0.3 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 CtIP_N PF10482.9 KDO34629.1 - 0.011 15.7 4.3 0.027 14.5 4.3 1.6 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain HMMR_N PF15905.5 KDO34629.1 - 0.025 14.1 4.6 0.036 13.6 4.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal WD40_like PF17005.5 KDO34629.1 - 0.042 13.2 0.1 4.1 6.6 0.1 2.9 4 0 0 4 4 4 0 WD40-like domain Viral_env_E26 PF11050.8 KDO34629.1 - 0.11 11.9 1.8 0.18 11.2 1.1 1.6 2 0 0 2 2 2 0 Virus envelope protein E26 EzrA PF06160.12 KDO34629.1 - 0.11 10.6 2.4 0.15 10.2 2.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Alpha-mann_mid PF09261.11 KDO34629.1 - 1.6 8.9 5.3 0.99 9.6 1.3 2.7 2 1 1 3 3 3 0 Alpha mannosidase middle domain AstE_AspA PF04952.14 KDO34630.1 - 6.6e-17 61.5 0.0 8.4e-17 61.2 0.0 1.3 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Phage_holin_3_6 PF07332.11 KDO34631.1 - 0.55 10.3 5.9 0.98 9.5 5.9 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 KDO34632.1 - 7.3e-21 74.7 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34632.1 - 4.2e-11 42.6 0.0 7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO34632.1 - 3.3e-05 22.9 0.4 8.2e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KDO34632.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_2 PF07719.17 KDO34633.1 - 1.4e-35 118.5 17.9 1.1e-06 28.3 1.3 10.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34633.1 - 1.5e-33 113.2 16.9 1.6e-08 34.0 1.1 9.3 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KDO34633.1 - 1.6e-24 85.3 7.8 3e-11 42.8 0.2 7.6 6 3 3 9 9 8 3 TPR repeat TPR_8 PF13181.6 KDO34633.1 - 4.4e-21 73.3 13.1 2e-06 27.6 0.3 8.8 10 0 0 10 10 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO34633.1 - 8.3e-17 61.2 23.2 7.5e-09 35.7 0.0 7.5 5 2 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KDO34633.1 - 9e-17 59.8 10.3 7.3e-05 22.5 0.3 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34633.1 - 1.8e-16 60.2 22.5 4.7e-10 39.6 2.1 8.4 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34633.1 - 8.8e-16 57.3 17.7 0.00042 20.9 0.4 9.6 7 2 4 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO34633.1 - 5.7e-15 55.7 12.8 5.5e-07 30.1 0.4 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34633.1 - 7.7e-14 52.0 5.1 0.00016 22.1 0.1 6.7 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KDO34633.1 - 9.3e-12 44.5 12.0 0.0039 17.5 0.0 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34633.1 - 2.2e-08 34.2 13.7 0.034 14.8 0.6 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KDO34633.1 - 6.5e-08 32.2 12.9 0.061 13.2 2.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34633.1 - 3.3e-06 27.1 11.5 1.7e-05 24.9 1.3 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KDO34633.1 - 3.6e-05 23.7 13.8 0.0028 17.6 0.0 5.4 7 0 0 7 7 5 2 Tetratricopeptide repeat BTAD PF03704.17 KDO34633.1 - 0.00049 20.5 3.3 0.11 12.9 0.4 3.3 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 KDO34633.1 - 0.00052 19.3 4.8 0.67 9.1 0.2 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO34633.1 - 0.0016 18.9 5.6 2.6 8.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KDO34633.1 - 0.01 16.3 0.1 0.19 12.2 0.1 2.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation MIT PF04212.18 KDO34633.1 - 0.017 15.2 2.7 36 4.5 0.3 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KDO34633.1 - 0.034 14.2 3.8 1 9.4 0.4 4.0 4 2 0 4 4 3 0 Domain of Unknown Function (DUF3856) PknG_TPR PF16918.5 KDO34633.1 - 0.054 12.2 0.8 0.13 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat SHNi-TPR PF10516.9 KDO34633.1 - 0.13 11.7 4.9 3.3 7.3 0.2 3.1 3 0 0 3 3 3 0 SHNi-TPR SNAP PF14938.6 KDO34633.1 - 0.18 11.2 5.5 0.21 11.0 1.1 2.9 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KDO34633.1 - 3.4 7.0 11.9 0.45 9.8 0.8 4.2 4 2 3 7 7 7 0 MalT-like TPR region Aa_trans PF01490.18 KDO34634.1 - 6.9e-19 67.8 17.0 6.9e-19 67.8 17.0 2.7 2 1 1 3 3 3 2 Transmembrane amino acid transporter protein MutS_V PF00488.21 KDO34635.1 - 1.6e-65 220.7 0.1 3.2e-65 219.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KDO34635.1 - 6.1e-28 98.4 0.6 1.4e-27 97.2 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KDO34635.1 - 1.3e-05 25.5 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KDO34635.1 - 0.0023 18.2 0.0 0.0098 16.2 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV Leptin PF02024.15 KDO34635.1 - 0.12 12.1 2.4 0.14 11.9 0.5 2.1 2 0 0 2 2 2 0 Leptin AAA_29 PF13555.6 KDO34635.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RdRP PF05183.12 KDO34636.1 - 3.7e-139 465.1 0.0 4.5e-138 461.5 0.0 2.0 1 1 0 1 1 1 1 RNA dependent RNA polymerase DENN PF02141.21 KDO34637.1 - 2.5e-15 56.9 1.0 5.8e-15 55.7 0.1 2.0 2 1 0 2 2 2 1 DENN (AEX-3) domain RGS PF00615.19 KDO34637.1 - 1.9e-07 31.3 0.5 0.0019 18.5 0.0 2.9 3 0 0 3 3 3 2 Regulator of G protein signaling domain RSN1_7TM PF02714.15 KDO34638.1 - 1.5e-30 106.4 19.7 2.6e-30 105.6 19.7 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KDO34638.1 - 2.3e-11 43.7 2.0 2.3e-11 43.7 2.0 4.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KDO34638.1 - 1.6e-06 28.5 0.0 6.7e-05 23.2 0.0 2.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter HSF_DNA-bind PF00447.17 KDO34639.1 - 3.5e-24 85.3 0.3 5.6e-24 84.6 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4988 PF16378.5 KDO34639.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function PPR_2 PF13041.6 KDO34641.1 - 1.1e-34 118.3 8.4 1e-12 48.0 0.9 4.4 1 1 4 5 5 5 4 PPR repeat family PPR PF01535.20 KDO34641.1 - 1.1e-20 72.4 4.9 0.00014 21.8 0.4 4.7 5 0 0 5 5 5 4 PPR repeat PPR_1 PF12854.7 KDO34641.1 - 1.1e-18 66.7 3.9 1.9e-07 30.7 0.0 4.3 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.6 KDO34641.1 - 6.8e-17 61.3 0.3 1.4e-07 31.5 0.0 2.7 1 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KDO34641.1 - 8.2e-09 35.1 1.6 1.1e-07 31.4 2.4 2.1 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KDO34641.1 - 0.002 18.6 0.0 0.45 11.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_4 PF02390.17 KDO34641.1 - 0.006 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KDO34641.1 - 0.015 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DivIC PF04977.15 KDO34642.1 - 0.008 15.9 0.3 0.013 15.2 0.3 1.3 1 0 0 1 1 1 1 Septum formation initiator Asp_Glu_race PF01177.22 KDO34642.1 - 0.011 15.6 0.3 0.014 15.2 0.3 1.0 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase DUF4686 PF15742.5 KDO34642.1 - 0.014 14.5 0.2 0.015 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Spectrin PF00435.21 KDO34642.1 - 0.015 15.7 1.0 0.024 15.1 0.9 1.5 1 1 0 1 1 1 0 Spectrin repeat ATG16 PF08614.11 KDO34642.1 - 0.018 15.2 0.7 0.024 14.9 0.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KDO34642.1 - 0.034 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Nup54 PF13874.6 KDO34642.1 - 0.04 14.0 0.8 0.048 13.8 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LRR_6 PF13516.6 KDO34643.1 - 1.8e-09 36.9 0.0 2 8.6 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 KDO34643.1 - 1.9e-07 31.3 0.5 0.0062 16.9 0.2 5.2 3 2 3 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO34643.1 - 0.0043 17.4 7.2 6.1 7.8 0.0 6.3 7 1 0 7 7 7 1 Leucine Rich Repeat F-box PF00646.33 KDO34643.1 - 0.005 16.7 0.1 0.63 10.0 0.0 3.3 3 0 0 3 3 3 1 F-box domain SAM_Ste50p PF09235.10 KDO34643.1 - 0.082 13.2 1.5 5 7.4 0.1 3.9 3 2 1 4 4 4 0 Ste50p, sterile alpha motif DUF4442 PF14539.6 KDO34644.1 - 1.2e-31 109.5 0.2 1.4e-31 109.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) DAHP_synth_1 PF00793.20 KDO34645.1 - 1.6e-96 322.4 0.0 2.1e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Dzip-like_N PF13815.6 KDO34646.1 - 1.3e-31 109.0 8.3 1.3e-31 109.0 8.3 4.2 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal IQ PF00612.27 KDO34646.1 - 1.7e-06 27.3 9.6 0.051 13.4 0.1 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif ADIP PF11559.8 KDO34646.1 - 0.0075 16.4 4.2 0.0075 16.4 4.2 4.7 4 1 1 5 5 5 1 Afadin- and alpha -actinin-Binding HALZ PF02183.18 KDO34646.1 - 0.0082 16.3 0.8 0.0082 16.3 0.8 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper HAUS4 PF14735.6 KDO34646.1 - 0.0088 15.8 10.0 0.0088 15.8 10.0 3.3 2 1 0 3 3 3 1 HAUS augmin-like complex subunit 4 Thioredoxin_4 PF13462.6 KDO34647.1 - 2.7e-08 34.1 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KDO34647.1 - 4e-06 26.7 0.1 0.0023 17.8 0.0 2.4 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Aminotran_1_2 PF00155.21 KDO34648.1 - 2.1e-86 290.4 0.0 2.4e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Neuregulin PF02158.15 KDO34649.1 - 0.023 14.1 1.8 0.029 13.7 1.8 1.0 1 0 0 1 1 1 0 Neuregulin intracellular region CCT PF06203.14 KDO34649.1 - 0.22 11.6 3.6 0.35 11.0 3.6 1.2 1 0 0 1 1 1 0 CCT motif Tudor-knot PF11717.8 KDO34650.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HNH PF01844.23 KDO34650.1 - 0.0027 17.9 2.2 0.008 16.3 2.2 1.9 1 1 0 1 1 1 1 HNH endonuclease TUDOR PF00567.24 KDO34650.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Rhodanese_C PF12368.8 KDO34650.1 - 0.044 14.2 0.9 0.55 10.6 0.9 2.3 1 1 1 2 2 2 0 Rhodanase C-terminal zf-CCHC_5 PF14787.6 KDO34650.1 - 0.35 10.6 2.9 16 5.3 0.1 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger HSP70 PF00012.20 KDO34651.1 - 1.2e-61 208.7 4.3 1.2e-59 202.1 0.6 2.1 1 1 1 2 2 2 2 Hsp70 protein TPR_2 PF07719.17 KDO34651.1 - 7.8e-12 44.4 9.3 2.5e-06 27.2 0.4 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34651.1 - 1.9e-11 43.3 8.1 3.4e-05 23.5 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34651.1 - 2.7e-07 30.3 5.3 0.0037 17.4 1.2 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MreB_Mbl PF06723.13 KDO34651.1 - 5.9e-06 25.3 2.8 5.2e-05 22.2 1.7 2.5 2 1 0 2 2 2 1 MreB/Mbl protein TPR_12 PF13424.6 KDO34651.1 - 0.0007 19.8 7.6 0.0015 18.7 4.6 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO34651.1 - 0.0012 19.1 6.6 0.01 16.1 1.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34651.1 - 0.0015 18.5 4.8 0.036 14.1 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO34651.1 - 0.0016 18.6 9.5 0.0075 16.5 9.5 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KDO34651.1 - 0.002 17.8 4.0 0.51 10.1 3.1 3.1 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KDO34651.1 - 0.0034 17.8 1.9 0.0034 17.8 1.9 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34651.1 - 0.0047 17.0 1.2 0.024 14.8 1.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 KDO34651.1 - 0.01 16.0 0.4 0.01 16.0 0.4 2.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome C chaperone FGGY_C PF02782.16 KDO34651.1 - 0.013 15.2 1.9 0.02 14.6 0.9 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain TPR_16 PF13432.6 KDO34651.1 - 0.086 13.5 8.0 13 6.5 1.8 4.4 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34651.1 - 0.99 10.2 12.3 0.78 10.5 0.6 4.1 5 0 0 5 5 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KDO34651.1 - 1.5 9.0 10.5 2.3 8.3 2.2 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat NEMP PF10225.9 KDO34653.1 - 1.3e-16 61.1 10.5 1.3e-09 38.1 0.6 2.5 2 0 0 2 2 2 2 NEMP family DUF1461 PF07314.11 KDO34653.1 - 0.052 13.5 1.8 0.53 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF3341 PF11821.8 KDO34653.1 - 0.23 11.1 1.5 3.3 7.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Scaffolding_pro PF11418.8 KDO34654.1 - 0.77 10.4 7.8 1.3 9.6 0.4 3.2 1 1 2 3 3 3 0 Phi29 scaffolding protein PIN_8 PF18476.1 KDO34654.1 - 2 8.2 9.8 0.6 9.9 6.2 1.8 1 1 1 2 2 2 0 PIN like domain Exo_endo_phos PF03372.23 KDO34655.1 - 1.2e-10 41.3 0.2 1.9e-10 40.7 0.2 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 KDO34656.1 - 4.1e-65 219.8 0.0 4.9e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34656.1 - 5.6e-30 104.5 0.0 7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34656.1 - 7.6e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO34656.1 - 0.0018 17.7 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KDO34656.1 - 0.0022 17.1 0.1 0.0031 16.6 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ABC1 PF03109.16 KDO34656.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 KDO34656.1 - 0.015 15.2 2.0 1.2 9.0 0.7 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO34656.1 - 0.029 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KDO34656.1 - 0.048 13.3 0.3 0.077 12.6 0.3 1.4 1 1 0 1 1 1 0 RIO1 family RAMP4 PF06624.12 KDO34656.1 - 0.15 12.2 0.5 0.41 10.7 0.1 1.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Uds1 PF15456.6 KDO34657.1 - 0.16 12.2 3.8 0.29 11.3 3.8 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Pkinase PF00069.25 KDO34658.1 - 4.7e-54 183.5 0.0 6.5e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34658.1 - 5.9e-52 176.5 0.0 7.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO34658.1 - 1.4e-06 28.5 4.2 0.14 12.6 0.2 5.3 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KDO34658.1 - 0.00011 21.1 0.1 0.00017 20.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KDO34658.1 - 0.001 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KDO34658.1 - 0.016 15.2 0.0 0.04 13.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.12 KDO34658.1 - 0.063 13.5 6.7 4.2 7.6 0.8 3.8 2 1 1 4 4 4 0 FNIP Repeat FTA2 PF13095.6 KDO34658.1 - 0.1 12.2 0.0 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 KDO34659.1 - 1.3e-52 178.7 1.9 3.2e-52 177.4 1.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KDO34659.1 - 2.6e-42 144.5 5.1 1.4e-41 142.1 5.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO34659.1 - 3.7e-06 27.0 4.7 2.6e-05 24.2 1.2 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KDO34659.1 - 0.0012 18.4 2.1 0.0018 17.8 1.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Band_7 PF01145.25 KDO34660.1 - 5.7e-30 104.6 0.5 8.6e-30 104.1 0.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KDO34660.1 - 1.8e-26 91.9 1.7 4.4e-26 90.7 1.7 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 DUF4938 PF16292.5 KDO34660.1 - 0.048 13.0 1.7 0.082 12.2 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4938) Band_7_1 PF13421.6 KDO34660.1 - 0.08 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family Prenyltrans PF00432.21 KDO34662.1 - 5.7e-24 83.6 8.9 3.6e-07 29.8 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat CSRNP_N PF16019.5 KDO34663.1 - 0.058 13.3 0.8 0.18 11.7 0.8 1.8 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF3295 PF11702.8 KDO34663.1 - 0.89 8.8 5.5 1 8.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CSRNP_N PF16019.5 KDO34664.1 - 0.00089 19.2 1.1 0.0013 18.7 1.1 1.3 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus PBP1_TM PF14812.6 KDO34664.1 - 0.72 10.3 7.5 0.37 11.2 2.8 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 KDO34665.1 - 4e-12 45.7 44.5 2.2e-06 26.8 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KDO34665.1 - 9.6e-07 27.7 11.8 9.6e-07 27.7 11.8 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein APG6_N PF17675.1 KDO34668.1 - 0.003 18.1 17.2 0.0033 17.9 8.9 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region RTBV_P46 PF06216.11 KDO34668.1 - 0.059 12.3 0.2 0.096 11.6 0.2 1.3 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF812 PF05667.11 KDO34668.1 - 0.089 11.7 8.9 0.1 11.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Nitrophorin PF02087.15 KDO34668.1 - 0.13 12.3 0.3 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Nitrophorin HALZ PF02183.18 KDO34668.1 - 0.18 12.0 3.2 0.33 11.2 1.6 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 KDO34668.1 - 0.19 12.4 7.2 0.97 10.1 2.9 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DMPK_coil PF08826.10 KDO34668.1 - 0.49 10.5 10.0 0.32 11.1 4.5 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like FlxA PF14282.6 KDO34668.1 - 0.55 10.3 5.9 1.5 8.9 5.9 1.7 1 1 0 1 1 1 0 FlxA-like protein ADIP PF11559.8 KDO34668.1 - 1.2 9.2 11.3 0.07 13.2 4.0 2.2 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding eIF3_N PF09440.10 KDO34668.1 - 2.8 8.4 10.5 6.3 7.2 3.4 2.6 1 1 2 3 3 3 0 eIF3 subunit 6 N terminal domain TPR_MLP1_2 PF07926.12 KDO34668.1 - 6.3 6.9 20.4 3.6 7.7 8.7 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein RasGAP PF00616.19 KDO34669.1 - 1.8e-10 40.9 0.0 7e-09 35.7 0.0 2.1 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Epimerase PF01370.21 KDO34670.1 - 3.2e-54 184.0 0.0 4.1e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KDO34670.1 - 2.9e-15 56.5 0.2 1.3e-14 54.4 0.0 1.8 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KDO34670.1 - 1.7e-06 27.4 0.0 2.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KDO34670.1 - 0.0022 17.2 3.3 0.0099 15.0 0.3 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KDO34670.1 - 0.0089 15.1 0.3 0.11 11.5 0.3 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RRM_1 PF00076.22 KDO34671.1 - 2.7e-22 78.4 0.0 4e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO34671.1 - 8.3e-13 48.0 0.0 1.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KDO34671.1 - 4e-09 36.2 0.0 0.00019 21.2 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KDO34671.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 KorB_C PF06613.11 KDO34671.1 - 0.11 12.5 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain DUF3806 PF12713.7 KDO34671.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) CSRNP_N PF16019.5 KDO34673.1 - 2.2e-05 24.5 0.2 4.5e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus PBP1_TM PF14812.6 KDO34673.1 - 5.3 7.5 8.4 4.1 7.9 5.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0370 PF13980.6 KDO34673.1 - 9.7 6.3 8.7 0.56 10.3 3.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) CSRNP_N PF16019.5 KDO34674.1 - 0.006 16.5 0.1 0.013 15.5 0.1 1.6 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus HEAT PF02985.22 KDO34674.1 - 0.021 15.0 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat PH PF00169.29 KDO34675.1 - 0.027 15.0 0.0 0.074 13.6 0.0 1.7 2 0 0 2 2 2 0 PH domain LRR_4 PF12799.7 KDO34676.1 - 1e-05 25.8 0.1 0.15 12.5 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO34676.1 - 1.9e-05 24.4 1.0 0.085 13.0 0.0 3.4 4 0 0 4 4 4 2 Leucine Rich repeat F-box PF00646.33 KDO34676.1 - 0.01 15.7 0.1 0.032 14.1 0.1 1.8 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 KDO34676.1 - 0.047 13.5 1.8 17 5.3 0.0 4.4 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 KDO34676.1 - 0.089 13.4 0.3 81 4.4 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat CSRNP_N PF16019.5 KDO34677.1 - 3.3e-05 23.9 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus AAA_lid_3 PF17862.1 KDO34677.1 - 0.27 11.1 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA+ lid domain CSRNP_N PF16019.5 KDO34678.1 - 2.7e-06 27.5 4.0 1.6e-05 25.0 4.0 1.9 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus CSRNP_N PF16019.5 KDO34679.1 - 0.0023 17.9 4.3 0.0078 16.2 4.3 1.7 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus CSRNP_N PF16019.5 KDO34680.1 - 0.0054 16.7 0.9 0.0078 16.1 0.9 1.3 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus PBP1_TM PF14812.6 KDO34680.1 - 0.59 10.5 8.2 0.33 11.3 3.8 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NTPase_I-T PF01931.18 KDO34681.1 - 9e-56 188.2 0.0 1e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 MU2_FHA PF18221.1 KDO34681.1 - 0.1 12.6 0.0 2.2 8.4 0.0 2.2 1 1 1 2 2 2 0 Mutator 2 Fork head associated domain TMEM135_C_rich PF15982.5 KDO34683.1 - 0.029 15.0 0.3 0.07 13.7 0.2 1.7 1 1 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 MSL2-CXC PF16682.5 KDO34683.1 - 0.42 10.8 3.7 0.14 12.3 0.6 1.7 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Pkinase PF00069.25 KDO34684.1 - 3.9e-50 170.7 0.0 4.3e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34684.1 - 5.7e-29 101.2 0.0 6.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO34684.1 - 2.3e-05 23.8 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO34684.1 - 2.9e-05 23.5 0.1 0.00016 21.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KDO34684.1 - 0.00012 22.1 1.9 0.059 13.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Occludin_ELL PF07303.13 KDO34685.1 - 0.12 13.1 0.7 28 5.5 0.0 3.1 2 1 0 2 2 2 0 Occludin homology domain DUF2730 PF10805.8 KDO34685.1 - 0.3 11.2 8.3 5.1 7.2 0.4 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 KDO34685.1 - 0.76 9.8 9.4 2.2 8.3 0.0 4.3 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KDO34685.1 - 0.79 10.1 7.4 1.2 9.4 0.1 4.0 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 KDO34685.1 - 1.9 8.9 7.9 2 8.9 1.4 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) DNA_repr_REX1B PF14966.6 KDO34685.1 - 2.7 8.7 13.3 5.9 7.6 1.0 4.2 2 2 2 4 4 4 0 DNA repair REX1-B Seryl_tRNA_N PF02403.22 KDO34685.1 - 8.1 6.7 14.6 2.9 8.1 3.3 3.4 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 KDO34685.1 - 8.1 7.0 15.7 3.7 8.1 8.3 3.6 2 2 1 3 3 3 0 Spectrin repeat EPL1 PF10513.9 KDO34686.1 - 0.00024 21.5 6.5 0.29 11.5 4.2 3.2 2 1 0 2 2 2 2 Enhancer of polycomb-like G10 PF01125.17 KDO34686.1 - 0.25 11.1 0.9 0.64 9.8 0.4 1.8 1 1 0 1 1 1 0 G10 protein TPR_2 PF07719.17 KDO34688.1 - 6.6e-10 38.3 0.0 0.18 12.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34688.1 - 5.9e-07 29.7 7.4 0.00014 22.0 0.1 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34688.1 - 3e-06 26.8 0.0 0.62 10.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34688.1 - 1.2e-05 25.7 0.1 0.011 16.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34688.1 - 2.8e-05 24.0 0.0 0.24 11.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34688.1 - 4.1e-05 23.3 0.0 1.7 8.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO34688.1 - 8.5e-05 23.1 3.7 0.0054 17.3 0.4 3.0 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KDO34688.1 - 0.00018 21.8 1.4 1 10.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34688.1 - 0.00019 21.8 0.0 0.94 10.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KDO34688.1 - 0.00024 21.2 0.1 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34688.1 - 0.00062 20.4 3.8 0.094 13.6 0.0 3.8 2 1 2 4 4 3 1 Tetratricopeptide repeat Cohesin_load PF10345.9 KDO34688.1 - 0.0015 17.1 0.0 0.0021 16.6 0.0 1.1 1 0 0 1 1 1 1 Cohesin loading factor IQ PF00612.27 KDO34688.1 - 0.098 12.5 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_10 PF13374.6 KDO34688.1 - 0.43 10.5 0.0 0.43 10.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 KDO34689.1 - 8.1e-16 58.2 3.8 1.5e-09 38.2 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34689.1 - 1.9e-13 50.3 6.2 1e-11 44.8 1.9 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34689.1 - 1.2e-11 45.0 0.4 1.6e-11 44.6 0.4 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO34689.1 - 1.4e-09 38.0 7.4 5.3e-06 26.6 2.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KDO34689.1 - 5.4e-07 29.4 1.9 0.017 15.6 0.2 3.2 4 0 0 4 4 4 2 Ankyrin repeat HSF_DNA-bind PF00447.17 KDO34690.1 - 1.4e-29 102.5 1.1 2.2e-29 101.9 0.4 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding DASH_Dad2 PF08654.10 KDO34690.1 - 0.003 18.0 0.2 0.0051 17.2 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF5327 PF17261.2 KDO34690.1 - 0.01 16.5 4.3 0.027 15.2 4.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5327) DUF4208 PF13907.6 KDO34690.1 - 0.046 14.2 0.3 0.098 13.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) YlbD_coat PF14071.6 KDO34690.1 - 0.056 13.7 1.0 0.11 12.7 1.0 1.5 1 0 0 1 1 1 0 Putative coat protein DUF812 PF05667.11 KDO34690.1 - 0.06 12.2 0.2 0.07 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SKA1 PF07160.12 KDO34690.1 - 0.072 12.9 2.2 0.11 12.3 2.2 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4988 PF16378.5 KDO34690.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function CCDC53 PF10152.9 KDO34690.1 - 0.65 10.4 3.8 0.48 10.8 1.5 1.9 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex TcdA_TcdB_pore PF12920.7 KDO34691.1 - 0.25 9.5 0.1 0.36 9.0 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Transket_pyr PF02779.24 KDO34692.1 - 5.3e-46 156.5 0.0 8.7e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KDO34692.1 - 4.9e-43 146.0 0.9 1.1e-42 144.8 0.5 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KDO34692.1 - 0.00053 20.3 0.1 0.0014 18.9 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Caveolin PF01146.17 KDO34693.1 - 5.8 6.9 8.5 2.9 7.8 3.2 2.3 2 0 0 2 2 2 0 Caveolin Cyclin_N PF00134.23 KDO34695.1 - 1.3e-26 92.8 0.4 1.9e-26 92.3 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO34695.1 - 0.021 14.9 0.3 0.099 12.7 0.0 2.2 3 0 0 3 3 3 0 Cyclin, C-terminal domain Ribosomal_L23 PF00276.20 KDO34696.1 - 1.2e-15 57.6 1.6 1.2e-15 57.6 1.6 2.5 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 KDO34696.1 - 1.3e-11 44.5 11.8 4.1e-11 42.9 11.8 1.9 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain YihI PF04220.12 KDO34696.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Der GTPase activator (YihI) RPA PF10134.9 KDO34696.1 - 0.033 13.7 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 Replication initiator protein A Hydrolase_2 PF07486.12 KDO34696.1 - 0.08 13.8 0.1 0.16 12.9 0.1 1.5 1 0 0 1 1 1 0 Cell Wall Hydrolase TusA PF01206.17 KDO34696.1 - 0.15 11.9 0.4 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Sulfurtransferase TusA IspA PF04279.15 KDO34697.1 - 0.00045 20.4 1.2 0.00045 20.4 1.2 1.7 2 0 0 2 2 2 1 Intracellular septation protein A DUF3159 PF11361.8 KDO34697.1 - 0.13 12.0 9.9 0.2 11.4 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) ADH_N PF08240.12 KDO34698.1 - 2e-25 88.8 5.5 3.4e-25 88.0 5.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KDO34698.1 - 1.3e-18 67.2 0.1 2.3e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO34698.1 - 1.9e-08 35.4 0.0 2.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KDO34698.1 - 3.9e-06 26.3 0.1 6.5e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KDO34698.1 - 0.0018 17.7 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KDO34698.1 - 0.17 12.5 0.9 2.2 8.9 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.12 KDO34699.1 - 2e-14 53.4 0.2 2.7e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KDO34699.1 - 6.3e-10 39.1 0.0 9.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KDO34699.1 - 6.3e-09 37.0 0.0 8.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase_Tyr PF07714.17 KDO34701.1 - 6.6e-60 202.6 0.0 8.7e-56 189.1 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KDO34701.1 - 4e-50 170.6 0.0 4.1e-41 141.1 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 KDO34701.1 - 0.00092 18.6 0.6 0.18 11.2 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KDO34701.1 - 0.0045 16.0 0.1 0.37 9.7 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KDO34701.1 - 0.018 14.4 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like ABC1 PF03109.16 KDO34701.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 KDO34701.1 - 0.23 11.4 7.9 4.8 7.0 0.4 3.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family CAF1 PF04857.20 KDO34705.1 - 2.3e-21 76.3 0.3 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 2 CAF1 family ribonuclease SRPRB PF09439.10 KDO34706.1 - 5.8e-35 120.3 0.0 7.5e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KDO34706.1 - 5.4e-14 52.0 0.0 7.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KDO34706.1 - 4.6e-09 36.5 0.0 6.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KDO34706.1 - 2.8e-07 30.3 0.0 3.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KDO34706.1 - 5.5e-06 26.4 0.0 7.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KDO34706.1 - 3.4e-05 23.3 0.0 4.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KDO34706.1 - 6e-05 22.7 0.0 0.0012 18.5 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KDO34706.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 KDO34706.1 - 0.0059 16.8 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KDO34706.1 - 0.011 16.0 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KDO34706.1 - 0.02 15.3 0.2 0.062 13.7 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KDO34706.1 - 0.024 14.4 0.4 0.57 9.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KDO34706.1 - 0.025 14.5 0.0 0.27 11.1 0.0 2.1 1 1 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KDO34706.1 - 0.028 14.4 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tir_receptor_C PF07489.11 KDO34706.1 - 0.031 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mg_chelatase PF01078.21 KDO34706.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 KDO34706.1 - 0.088 12.6 0.0 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KDO34706.1 - 0.1 12.9 0.2 0.21 12.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 KDO34706.1 - 0.1 12.2 0.3 3 7.4 0.1 2.2 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KDO34706.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KDO34706.1 - 0.14 11.8 0.7 0.49 10.0 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_PrkA PF08298.11 KDO34706.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Ribosomal_L36 PF00444.18 KDO34707.1 - 4.7e-21 74.7 12.0 5.8e-21 74.4 12.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 FBP_C PF16571.5 KDO34707.1 - 0.029 13.9 0.7 0.034 13.7 0.7 1.1 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger FKBP_C PF00254.28 KDO34708.1 - 7.8e-33 112.7 0.0 9.6e-33 112.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1778 PF08681.11 KDO34709.1 - 0.04 13.9 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Ribosomal_L29 PF00831.23 KDO34709.1 - 0.069 13.1 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein LapA_dom PF06305.11 KDO34709.1 - 0.23 11.3 1.3 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain adh_short PF00106.25 KDO34710.1 - 3.2e-48 163.8 0.7 4.1e-48 163.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO34710.1 - 3.3e-33 115.2 0.3 4.6e-33 114.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO34710.1 - 1.9e-13 50.8 0.4 3.1e-13 50.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KDO34710.1 - 0.0018 17.8 0.6 0.012 15.1 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KDO34710.1 - 0.0026 17.7 0.8 0.0046 16.9 0.8 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KDO34710.1 - 0.032 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.18 KDO34710.1 - 0.095 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YabA PF06156.13 KDO34712.1 - 0.007 17.0 6.1 0.013 16.1 6.1 1.5 1 0 0 1 1 1 1 Initiation control protein YabA DUF4407 PF14362.6 KDO34712.1 - 0.1 11.9 8.0 0.15 11.3 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KDO34712.1 - 0.18 12.0 13.3 0.26 11.5 13.3 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KDO34712.1 - 0.24 10.2 13.9 0.33 9.8 13.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MutS_III PF05192.18 KDO34712.1 - 0.27 11.4 7.4 0.38 11.0 7.4 1.2 1 0 0 1 1 1 0 MutS domain III DUF724 PF05266.14 KDO34712.1 - 0.29 11.0 11.6 0.43 10.4 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 KDO34712.1 - 0.29 11.3 10.8 1 9.5 10.8 2.0 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 V_ATPase_I PF01496.19 KDO34712.1 - 0.3 9.0 4.7 0.34 8.8 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28_assoc PF14775.6 KDO34712.1 - 0.39 10.9 9.8 2.8 8.1 0.3 3.2 2 1 0 2 2 2 0 Sperm tail C-terminal domain FAM76 PF16046.5 KDO34712.1 - 0.47 9.8 6.3 0.59 9.4 6.3 1.1 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 KDO34712.1 - 1.3 8.1 13.2 1.6 7.7 13.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KDO34712.1 - 1.9 9.2 12.2 2.8e+02 2.2 0.2 3.5 1 1 1 2 2 2 0 SlyX BCL_N PF04714.13 KDO34712.1 - 3 8.0 5.7 3.3 7.9 0.4 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region TMPIT PF07851.13 KDO34712.1 - 4.6 6.4 5.8 5.6 6.1 5.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 KDO34712.1 - 7.7 7.0 21.7 44 4.6 18.2 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 KDO34713.1 - 3.8e-70 236.3 0.0 5e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34713.1 - 4.3e-43 147.5 0.0 5.8e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO34713.1 - 1.3e-08 34.5 0.0 4.1e-07 29.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KDO34713.1 - 2e-08 33.9 0.3 3.2e-08 33.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KDO34713.1 - 3.6e-07 29.9 0.2 6.7e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KDO34713.1 - 1.1e-06 27.8 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KDO34713.1 - 0.00042 20.0 0.1 0.00078 19.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO34713.1 - 0.017 15.1 0.0 0.06 13.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO34713.1 - 0.088 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DENN PF02141.21 KDO34714.1 - 1.2e-31 110.1 9.9 4.5e-31 108.3 3.8 3.1 3 1 0 3 3 3 1 DENN (AEX-3) domain RGS PF00615.19 KDO34714.1 - 3.4e-10 40.2 0.3 4.5e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Regulator of G protein signaling domain dDENN PF03455.19 KDO34714.1 - 7.1e-06 25.9 0.6 7.1e-06 25.9 0.6 2.6 2 0 0 2 2 2 1 dDENN domain Avl9 PF09794.9 KDO34714.1 - 0.00089 18.1 0.0 0.0025 16.6 0.0 1.7 1 0 0 1 1 1 1 Transport protein Avl9 TPR_12 PF13424.6 KDO34716.1 - 0.021 15.1 4.2 0.021 15.1 4.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34716.1 - 0.033 15.0 2.7 0.77 10.7 2.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34716.1 - 0.17 11.7 4.8 0.7 9.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KDO34716.1 - 1.8 8.6 6.6 12 5.9 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad51 PF08423.11 KDO34717.1 - 0.0005 19.4 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KDO34717.1 - 0.0018 17.9 0.1 0.0024 17.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KDO34717.1 - 0.12 11.6 0.0 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 KaiC Ank_4 PF13637.6 KDO34718.1 - 6.4e-17 61.7 5.5 1.5e-12 47.8 0.5 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34718.1 - 1.7e-13 50.9 0.1 5.2e-13 49.4 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34718.1 - 7.1e-12 45.3 0.8 2.2e-09 37.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34718.1 - 7.7e-12 44.3 0.4 6e-05 23.1 0.0 3.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KDO34718.1 - 7e-10 38.9 0.9 0.00024 21.4 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Glyco_transf_28 PF03033.20 KDO34719.1 - 3.3e-11 43.4 0.0 6.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KDO34719.1 - 4.8e-06 25.7 0.0 1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KDO34719.1 - 0.0008 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Calreticulin PF00262.18 KDO34720.1 - 7.4e-109 364.0 12.6 2e-78 263.8 2.8 2.3 1 1 1 2 2 2 2 Calreticulin family Lipase_3 PF01764.25 KDO34721.1 - 7.8e-05 22.6 0.2 0.00024 21.0 0.2 1.8 1 1 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KDO34721.1 - 0.00055 20.1 0.0 0.00082 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain FYVE PF01363.21 KDO34722.1 - 2.8e-17 62.6 9.2 5.4e-17 61.7 9.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO34722.1 - 3e-05 24.2 2.6 4.7e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger EF1G PF00647.19 KDO34723.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain PA PF02225.22 KDO34724.1 - 0.0021 18.0 0.3 0.0043 17.0 0.2 1.7 1 1 1 2 2 2 1 PA domain Aa_trans PF01490.18 KDO34726.1 - 1.3e-45 155.8 21.5 1.6e-45 155.6 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2518 PF10726.9 KDO34726.1 - 0.082 12.6 4.1 0.21 11.2 0.2 2.9 3 0 0 3 3 3 0 Protein of function (DUF2518) Cyt-b5 PF00173.28 KDO34727.1 - 3.3e-18 65.6 0.0 4.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CSL PF05207.13 KDO34728.1 - 5.9e-10 38.7 2.5 5.5e-08 32.4 2.5 2.2 1 1 0 1 1 1 1 CSL zinc finger HR1 PF02185.16 KDO34729.1 - 0.17 12.1 3.6 0.49 10.5 3.6 1.8 1 0 0 1 1 1 0 Hr1 repeat GMC_oxred_N PF00732.19 KDO34731.1 - 1.1e-85 287.6 0.0 2e-85 286.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KDO34731.1 - 1.6e-36 126.0 0.1 2.5e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KDO34731.1 - 0.00013 22.1 0.0 0.00061 20.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KDO34731.1 - 0.0018 17.4 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KDO34731.1 - 0.0055 16.3 1.7 0.026 14.1 1.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KDO34731.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KDO34731.1 - 0.059 13.6 0.0 0.27 11.5 0.0 2.1 2 1 1 3 3 3 0 TrkA-N domain Pyr_redox_2 PF07992.14 KDO34731.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO34731.1 - 0.24 10.1 0.1 0.62 8.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein LRR_8 PF13855.6 KDO34732.1 - 1.9e-06 27.5 4.5 5.4e-06 26.1 1.5 2.9 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KDO34732.1 - 2.3e-06 27.9 6.3 0.0039 17.6 4.3 4.0 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) Notch PF00066.17 KDO34732.1 - 2.4e-05 24.7 8.0 5.4e-05 23.6 8.0 1.6 1 0 0 1 1 1 1 LNR domain LRR_9 PF14580.6 KDO34732.1 - 0.0034 16.9 1.4 0.012 15.2 1.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeat MFS_2 PF13347.6 KDO34733.1 - 3e-07 29.3 33.1 1.6e-05 23.6 19.5 3.2 2 2 0 2 2 2 2 MFS/sugar transport protein ENTH PF01417.20 KDO34735.1 - 2.1e-11 43.9 0.0 5e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 KDO34735.1 - 0.0007 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 ANTH domain RasGEF_N_2 PF14663.6 KDO34735.1 - 0.24 11.8 0.2 2.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Q_salvage PF10343.9 KDO34736.1 - 3.3e-75 253.3 0.0 4.9e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family AMP-binding PF00501.28 KDO34737.1 - 3.6e-83 279.5 0.0 4.7e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO34737.1 - 0.00016 22.6 0.6 0.00037 21.4 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO34738.1 - 2.2e-75 253.8 0.1 3e-75 253.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KDO34738.1 - 1.3e-08 34.2 0.6 0.01 15.6 0.8 5.5 6 1 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 KDO34738.1 - 0.00075 20.4 0.0 0.0023 18.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KDO34738.1 - 0.0088 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 KDO34738.1 - 0.01 15.6 7.5 0.12 12.2 0.7 5.0 6 0 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase AA_permease PF00324.21 KDO34739.1 - 3.4e-19 68.8 43.6 4.9e-19 68.3 43.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KDO34739.1 - 1.8e-18 66.6 46.4 2.9e-18 65.9 46.1 1.4 1 1 0 1 1 1 1 Amino acid permease DUF2516 PF10724.9 KDO34739.1 - 1.7 9.0 8.3 0.42 10.9 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) AA_permease_2 PF13520.6 KDO34740.1 - 4.1e-18 65.4 45.8 6.5e-18 64.8 45.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KDO34740.1 - 7.1e-17 61.2 44.2 1.7e-16 59.9 44.2 1.6 1 1 0 1 1 1 1 Amino acid permease Hydrolase_4 PF12146.8 KDO34741.1 - 7.5e-10 38.5 0.0 3.9e-08 32.9 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO34741.1 - 5.9e-09 36.0 0.1 1.8e-06 27.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO34741.1 - 1.4e-06 29.1 1.0 2.1e-06 28.5 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KDO34741.1 - 0.00031 20.5 0.1 0.00042 20.0 0.1 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KDO34741.1 - 0.0023 17.6 0.0 0.0072 16.0 0.0 1.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KDO34741.1 - 0.0029 17.5 0.1 0.0037 17.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KDO34741.1 - 0.0044 16.9 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 KDO34741.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Glycos_transf_1 PF00534.20 KDO34742.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO34742.1 - 0.042 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 PilS PF08805.11 KDO34743.1 - 0.0089 15.9 0.2 0.011 15.5 0.2 1.1 1 0 0 1 1 1 1 PilS N terminal Glycos_transf_1 PF00534.20 KDO34744.1 - 3e-06 26.9 0.0 1.2e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KDO34744.1 - 0.0013 19.2 0.0 0.0026 18.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KDO34744.1 - 0.011 16.1 0.2 0.096 13.1 0.2 2.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 MFS_2 PF13347.6 KDO34746.1 - 1e-07 30.9 35.7 1.8e-07 30.1 14.9 3.0 2 2 1 3 3 3 2 MFS/sugar transport protein Mannosyl_trans3 PF11051.8 KDO34747.1 - 3.5e-32 111.9 0.0 1.7e-21 76.8 0.0 2.2 1 1 0 2 2 2 2 Mannosyltransferase putative ATP-synt_Z PF16594.5 KDO34747.1 - 0.35 10.4 3.1 0.51 9.9 0.1 2.4 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated Acatn PF13000.7 KDO34748.1 - 5e-113 378.5 23.2 2.8e-66 224.2 7.1 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 KH_8 PF17903.1 KDO34750.1 - 1.3e-31 108.5 1.6 1.4e-31 108.4 0.2 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain CALM_bind PF16025.5 KDO34750.1 - 0.64 10.5 5.4 1.5 9.4 5.4 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding HrpB7 PF09486.10 KDO34751.1 - 0.00051 20.5 11.1 0.00051 20.5 11.1 2.3 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 KDO34751.1 - 0.0057 17.1 0.6 2.5 8.6 0.0 3.0 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KDO34751.1 - 0.033 14.5 7.2 4.4 7.7 0.2 3.6 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laps PF10169.9 KDO34751.1 - 0.087 13.4 4.2 0.12 12.9 3.1 1.8 1 1 1 2 2 2 0 Learning-associated protein Gly_acyl_tr_N PF06021.11 KDO34751.1 - 0.13 12.4 0.9 0.3 11.2 0.1 1.9 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase TACC_C PF05010.14 KDO34751.1 - 0.26 11.1 13.6 0.17 11.6 5.9 2.8 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 KDO34751.1 - 0.31 11.2 13.9 0.63 10.3 3.4 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 KDO34751.1 - 0.41 11.1 11.6 14 6.2 4.4 3.6 1 1 1 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 KDO34751.1 - 0.41 9.5 13.3 0.77 8.6 1.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Med9 PF07544.13 KDO34751.1 - 0.46 10.6 9.3 6.1 7.0 0.1 3.6 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FTA4 PF13093.6 KDO34751.1 - 0.61 10.0 14.8 3.6 7.4 7.7 2.1 1 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF489 PF04356.12 KDO34751.1 - 0.8 9.7 6.5 0.24 11.4 2.5 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF489) DivIC PF04977.15 KDO34751.1 - 1.4 8.8 12.2 7.4 6.4 2.7 3.6 2 1 1 3 3 3 0 Septum formation initiator BST2 PF16716.5 KDO34751.1 - 1.4 9.5 11.5 1.4 9.6 2.1 3.2 2 2 0 2 2 2 0 Bone marrow stromal antigen 2 KxDL PF10241.9 KDO34751.1 - 1.9 8.8 10.5 1.7 9.0 2.0 3.6 2 2 2 4 4 4 0 Uncharacterized conserved protein APG6_N PF17675.1 KDO34751.1 - 3.9 8.0 17.4 1.2 9.7 1.5 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 KDO34751.1 - 5.2 7.2 10.7 0.51 10.5 0.3 3.8 3 2 2 5 5 5 0 bZIP transcription factor YabA PF06156.13 KDO34751.1 - 5.4 7.7 8.8 13 6.4 1.0 2.8 1 1 1 3 3 3 0 Initiation control protein YabA MscS_porin PF12795.7 KDO34751.1 - 8.3 5.9 19.6 0.11 12.0 3.7 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FKBP_C PF00254.28 KDO34753.1 - 9e-36 122.1 0.0 1.1e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IF4E PF01652.18 KDO34754.1 - 2e-39 134.9 0.8 2.5e-39 134.6 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E YrhK PF14145.6 KDO34755.1 - 6.7e-26 89.9 28.2 1.4e-10 40.9 1.6 3.4 3 0 0 3 3 3 3 YrhK-like protein DUF4386 PF14329.6 KDO34755.1 - 0.043 13.7 0.5 0.043 13.7 0.5 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4386) TraQ PF09679.10 KDO34755.1 - 0.35 10.8 1.4 23 5.0 0.6 2.8 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF3668 PF12416.8 KDO34756.1 - 1.2e-16 61.3 0.0 2.9e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Cep120 protein PRIMA1 PF16101.5 KDO34756.1 - 0.08 13.0 0.3 0.08 13.0 0.3 2.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF983 PF06170.12 KDO34756.1 - 0.13 12.7 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF983) SNF2_N PF00176.23 KDO34757.1 - 1e-69 234.9 0.3 2.3e-69 233.8 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KDO34757.1 - 2.5e-34 117.7 0.2 2.2e-33 114.7 0.2 2.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 KDO34757.1 - 8.7e-19 67.9 0.0 3.8e-18 65.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO34757.1 - 1.7e-09 37.9 0.4 1.2e-08 35.2 0.0 2.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 KDO34757.1 - 7.8e-06 26.4 0.1 7.8e-06 26.4 0.1 3.1 2 1 0 2 2 1 1 HMG-box domain HDA2-3 PF11496.8 KDO34757.1 - 9.1e-06 25.0 0.0 9.1e-06 25.0 0.0 2.3 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 KDO34757.1 - 1.4e-05 25.2 0.0 7.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD PF00270.29 KDO34757.1 - 1.8e-05 24.6 0.0 8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HMG_box PF00505.19 KDO34757.1 - 9.3e-05 22.8 0.0 9.3e-05 22.8 0.0 3.1 3 0 0 3 3 2 1 HMG (high mobility group) box Myb_DNA-bind_6 PF13921.6 KDO34757.1 - 0.0021 18.3 0.8 0.012 15.9 0.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_22 PF13401.6 KDO34757.1 - 0.12 12.7 0.3 5.3 7.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain Tyrosinase PF00264.20 KDO34757.1 - 0.24 11.7 1.9 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Common central domain of tyrosinase PP2C PF00481.21 KDO34758.1 - 4.2e-48 164.2 0.0 2.6e-47 161.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO34758.1 - 5.9e-05 22.8 0.1 0.00037 20.2 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C CMAS PF02353.20 KDO34759.1 - 1.3e-87 293.6 0.9 1.6e-87 293.3 0.9 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KDO34759.1 - 2e-13 50.8 0.0 4.8e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO34759.1 - 9.7e-11 42.2 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO34759.1 - 1.4e-10 41.1 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO34759.1 - 5.7e-10 39.3 0.0 9.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO34759.1 - 8.9e-08 32.8 0.0 1.6e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO34759.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KDO34759.1 - 0.0013 18.4 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KDO34759.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KDO34759.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KDO34759.1 - 0.036 13.7 0.0 0.066 12.8 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KDO34759.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 KDO34759.1 - 0.096 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FYVE PF01363.21 KDO34760.1 - 2e-21 75.9 76.6 5.4e-09 36.1 13.2 5.6 5 0 0 5 5 5 4 FYVE zinc finger FYVE_2 PF02318.16 KDO34760.1 - 0.0067 16.6 56.6 0.014 15.6 8.1 4.6 4 0 0 4 4 4 3 FYVE-type zinc finger FYVE PF01363.21 KDO34762.1 - 3.2e-11 43.2 15.7 7.4e-11 42.0 15.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO34762.1 - 0.001 19.3 8.0 0.002 18.3 8.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4428 PF14471.6 KDO34762.1 - 5.2 7.1 8.6 12 5.9 8.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) PAPS_reduct PF01507.19 KDO34763.1 - 1e-25 90.8 0.0 1.3e-23 83.9 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FYVE PF01363.21 KDO34764.1 - 3.3e-08 33.6 9.7 8.3e-08 32.3 9.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO34764.1 - 2.3e-05 24.6 3.3 5.5e-05 23.4 3.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger BK_channel_a PF03493.18 KDO34765.1 - 1.3e-15 57.4 0.0 2.7e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KDO34765.1 - 1.2e-13 50.8 0.4 3.7e-13 49.2 0.4 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KDO34765.1 - 2.1e-12 46.8 8.1 3.8e-12 45.9 8.1 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KDO34765.1 - 1.4e-06 28.5 0.0 0.00017 21.8 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.26 KDO34765.1 - 0.0072 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Glyco_hydro_14 PF01373.17 KDO34766.1 - 2.5e-92 309.9 1.2 3e-92 309.7 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 FYVE PF01363.21 KDO34768.1 - 5.3e-14 52.1 16.8 9.3e-14 51.3 16.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 KDO34768.1 - 5.4e-09 36.8 0.4 1e-08 35.9 0.1 1.7 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 KDO34768.1 - 0.14 12.3 9.1 0.28 11.4 9.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Pyridox_oxase_2 PF12766.7 KDO34769.1 - 8.3e-27 93.7 0.0 1.3e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KDO34769.1 - 1.5e-15 57.2 0.0 2.6e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cnn_1N PF07989.11 KDO34771.1 - 0.01 16.0 0.3 0.016 15.4 0.3 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF1279 PF06916.13 KDO34771.1 - 0.022 15.3 0.1 0.065 13.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) OmpH PF03938.14 KDO34771.1 - 0.025 14.9 0.2 0.038 14.3 0.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 KDO34771.1 - 0.028 14.5 2.0 0.042 13.9 2.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 KDO34771.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 KDO34771.1 - 0.65 10.3 4.5 1.1 9.5 4.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper MFS_2 PF13347.6 KDO34772.1 - 7.9e-07 28.0 9.6 7.9e-07 28.0 9.6 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein CytoC_RC PF02276.18 KDO34773.1 - 0.067 12.6 0.0 0.074 12.4 0.0 1.0 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Pyridoxal_deC PF00282.19 KDO34774.1 - 5.4e-73 245.9 0.0 8e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HORMA PF02301.18 KDO34775.1 - 5.4e-07 29.4 0.0 3.1e-06 26.9 0.0 1.8 1 1 1 2 2 2 1 HORMA domain PDZ PF00595.24 KDO34776.1 - 1.9e-16 60.1 0.0 0.0097 16.2 0.0 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KDO34776.1 - 4.2e-14 52.1 0.3 0.098 12.5 0.0 5.8 6 0 0 6 6 6 5 PDZ domain zf-MYND PF01753.18 KDO34776.1 - 1.1e-06 28.6 8.1 2e-06 27.8 8.1 1.4 1 0 0 1 1 1 1 MYND finger PDZ_2 PF13180.6 KDO34776.1 - 0.067 13.5 0.3 8.9 6.7 0.0 3.9 5 0 0 5 5 5 0 PDZ domain PriA_CRR PF18319.1 KDO34776.1 - 0.11 12.6 1.8 0.32 11.0 1.8 1.8 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain zf-Mss51 PF13824.6 KDO34776.1 - 1.1 9.3 8.3 3.9 7.6 8.3 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PRORP PF16953.5 KDO34779.1 - 2.7e-44 151.5 0.2 1.6e-43 149.0 0.1 1.9 2 0 0 2 2 2 1 Protein-only RNase P PPR_long PF17177.4 KDO34779.1 - 1.8e-40 138.6 5.4 2.3e-40 138.2 2.8 2.0 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KDO34779.1 - 7.7e-09 35.5 1.7 0.00089 19.3 0.3 4.0 2 2 1 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 KDO34779.1 - 4.9e-08 33.0 2.3 0.011 15.9 0.3 4.3 2 2 3 5 5 5 2 PPR repeat family PPR PF01535.20 KDO34779.1 - 2e-06 27.6 0.2 0.16 12.3 0.2 4.5 4 0 0 4 4 4 1 PPR repeat RNase_Zc3h12a PF11977.8 KDO34779.1 - 6.8e-05 22.7 0.1 0.00039 20.2 0.1 2.2 2 1 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Phage_ABA_S PF18066.1 KDO34779.1 - 0.046 14.4 2.1 3 8.6 0.0 4.0 3 1 1 4 4 4 0 Phage ABA sandwich domain DUF2497 PF10691.9 KDO34779.1 - 0.075 13.5 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) PPR_1 PF12854.7 KDO34779.1 - 0.098 12.4 1.2 5.9 6.7 0.1 3.0 3 0 0 3 3 3 0 PPR repeat Pkinase_Tyr PF07714.17 KDO34780.1 - 4.7e-34 117.8 0.0 9.6e-34 116.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34780.1 - 1.6e-30 106.4 0.0 2.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_5 PF13854.6 KDO34781.1 - 1.3e-27 95.2 1.1 1e-06 28.6 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KDO34781.1 - 6.2e-27 93.3 18.2 2.4e-08 34.0 0.1 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KDO34781.1 - 8.6e-24 83.3 15.0 7.5e-07 29.1 0.0 7.3 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO34781.1 - 4.9e-21 74.3 8.9 2.4e-05 24.4 0.1 6.7 5 1 2 7 7 6 4 Kelch motif Kelch_2 PF07646.15 KDO34781.1 - 9.3e-20 69.8 1.0 0.00052 19.9 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KDO34781.1 - 8.1e-15 54.1 6.0 0.0093 15.5 1.1 6.6 5 2 0 5 5 5 3 Kelch motif zf-RING_2 PF13639.6 KDO34781.1 - 6.6e-13 48.8 4.9 1.5e-12 47.6 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KDO34781.1 - 7.3e-11 42.2 3.6 1.6e-10 41.1 3.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KDO34781.1 - 6e-09 35.6 5.6 1.1e-08 34.7 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO34781.1 - 2.4e-08 33.6 2.6 4.6e-08 32.7 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KDO34781.1 - 1.8e-07 31.1 0.7 4.7e-07 29.8 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KDO34781.1 - 4.2e-07 29.7 4.4 7.3e-07 29.0 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO34781.1 - 9.4e-07 28.7 2.8 1.7e-06 27.9 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO34781.1 - 6e-06 26.0 1.7 9.9e-06 25.3 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO34781.1 - 4.2e-05 23.5 2.9 9.4e-05 22.4 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KDO34781.1 - 0.0042 16.7 2.9 0.0077 15.8 2.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KDO34781.1 - 0.0067 16.3 6.1 0.037 13.9 6.5 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KDO34781.1 - 0.035 14.0 0.4 0.035 14.0 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KDO34781.1 - 0.04 14.1 4.1 0.18 12.0 4.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KDO34781.1 - 0.093 12.9 5.4 0.2 11.9 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RAG2 PF03089.14 KDO34781.1 - 0.11 11.5 0.0 11 4.9 0.0 2.5 1 1 1 2 2 2 0 Recombination activating protein 2 PHD PF00628.29 KDO34781.1 - 0.13 12.1 3.2 0.25 11.3 3.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 KDO34781.1 - 0.16 11.8 2.1 0.3 10.9 2.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 KDO34781.1 - 0.43 10.8 4.0 0.93 9.7 4.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KDO34781.1 - 0.51 10.2 3.4 1.1 9.1 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KDO34781.1 - 0.54 10.3 6.8 1.5 8.9 1.7 2.5 2 0 0 2 2 2 0 Zinc-finger Kelch_5 PF13854.6 KDO34782.1 - 3.7e-24 84.2 6.7 0.00031 20.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KDO34782.1 - 1.2e-19 70.0 19.4 2.4e-08 33.9 0.2 6.9 6 2 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KDO34782.1 - 3.1e-16 58.7 1.5 0.00014 21.3 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KDO34782.1 - 3.1e-15 55.8 12.5 0.0012 19.1 0.1 6.7 4 1 2 6 6 6 4 Kelch motif zf-RING_2 PF13639.6 KDO34782.1 - 1.2e-12 47.9 5.9 1.9e-12 47.3 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain Kelch_3 PF13415.6 KDO34782.1 - 8.5e-11 41.9 22.8 0.00063 20.0 0.1 6.7 7 0 0 7 7 6 3 Galactose oxidase, central domain zf-RING_11 PF17123.5 KDO34782.1 - 2.3e-09 36.8 2.8 4.2e-09 36.0 2.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger Kelch_2 PF07646.15 KDO34782.1 - 8.3e-08 31.9 11.2 0.1 12.6 0.0 5.7 6 2 0 6 6 5 3 Kelch motif zf-C3HC4 PF00097.25 KDO34782.1 - 2.3e-07 30.6 4.4 3.5e-07 30.0 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KDO34782.1 - 3.2e-07 30.1 5.7 5.1e-07 29.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KDO34782.1 - 5.8e-07 29.7 8.6 2e-06 28.0 8.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO34782.1 - 9.3e-07 28.8 3.7 1.7e-06 28.0 3.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO34782.1 - 4.4e-06 26.6 3.3 6.7e-06 26.0 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KDO34782.1 - 0.00023 21.0 6.6 0.0017 18.2 7.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO34782.1 - 0.00075 19.5 3.8 0.0071 16.4 3.8 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO34782.1 - 0.0012 18.7 2.3 0.002 18.0 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KDO34782.1 - 0.0085 15.7 3.0 0.016 14.8 3.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO34782.1 - 0.0095 15.7 1.7 0.016 15.0 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KDO34782.1 - 0.011 15.9 3.3 0.041 14.1 3.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KDO34782.1 - 0.032 14.6 2.2 0.049 13.9 2.2 1.3 1 0 0 1 1 1 0 RING-like domain RAG2 PF03089.14 KDO34782.1 - 0.089 11.8 0.0 2 7.3 0.0 2.6 3 0 0 3 3 3 0 Recombination activating protein 2 zf-C3H2C3 PF17122.5 KDO34782.1 - 0.1 12.7 4.2 0.12 12.5 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 KDO34782.1 - 0.38 10.9 4.2 0.99 9.6 4.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 KDO34782.1 - 0.4 10.6 1.2 7.7 6.4 0.3 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 KDO34782.1 - 0.68 9.9 3.7 18 5.4 0.6 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger RINGv PF12906.7 KDO34782.1 - 1 9.5 4.1 2 8.6 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KDO34782.1 - 1 9.3 3.7 1.7 8.6 3.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KDO34782.1 - 1.1 9.1 3.8 2.2 8.2 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 KDO34782.1 - 7.5 6.9 7.5 19 5.6 0.4 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 KDO34783.1 - 4.4e-63 213.1 0.0 1.2e-39 136.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34783.1 - 2.9e-30 105.4 0.0 5.1e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KDO34783.1 - 7.8e-06 25.4 0.2 1.4e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO34783.1 - 1.6e-05 24.4 0.0 0.033 13.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Seadorna_VP7 PF07387.11 KDO34783.1 - 0.00039 19.6 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KDO34783.1 - 0.00095 19.1 0.2 0.42 10.5 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO34783.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KDO34783.1 - 0.057 13.0 0.0 4.6 6.8 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KDO34783.1 - 0.057 12.2 0.5 0.12 11.2 0.5 1.4 1 0 0 1 1 1 0 Fungal protein kinase tRNA_int_endo PF01974.17 KDO34784.1 - 1.5e-17 63.4 0.0 2.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pex16 PF08610.10 KDO34786.1 - 1.1e-58 199.0 0.0 1.3e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) UCH PF00443.29 KDO34787.1 - 6.6e-36 124.1 0.0 1.9e-35 122.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO34787.1 - 2.1e-11 44.0 0.7 3.2e-11 43.4 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4606 PF15379.6 KDO34787.1 - 0.018 15.2 0.2 3.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Lipase_3 PF01764.25 KDO34788.1 - 1.1e-29 103.1 0.0 2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KDO34788.1 - 6.1e-07 28.9 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KDO34788.1 - 4.8e-05 23.0 0.0 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KDO34788.1 - 0.0013 19.3 1.6 0.0013 19.3 1.6 2.8 2 1 0 3 3 3 1 Alpha/beta hydrolase family DUF900 PF05990.12 KDO34788.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 KDO34788.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain RNA_pol_Rpb1_1 PF04997.12 KDO34788.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Esterase PF00756.20 KDO34788.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CPP1-like PF11833.8 KDO34788.1 - 0.64 9.7 6.1 2 8.0 6.1 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ank_4 PF13637.6 KDO34789.1 - 3.3e-24 84.9 0.1 1.8e-09 37.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO34789.1 - 9.3e-23 80.6 0.1 3e-17 63.0 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34789.1 - 6.5e-14 51.8 3.7 1.6e-06 28.2 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KDO34789.1 - 2.9e-13 49.6 0.1 0.0048 17.3 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KDO34789.1 - 4.7e-12 45.0 0.1 0.0065 16.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Inv-AAD PF18785.1 KDO34790.1 - 7.6e-28 97.0 0.3 4.5e-26 91.2 0.3 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KDO34790.1 - 2.6e-21 75.4 0.3 3.1e-21 75.1 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KDO34790.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KDO34790.1 - 0.074 12.9 0.5 0.38 10.6 0.5 2.0 1 1 0 1 1 1 0 APOBEC-like N-terminal domain SNAD1 PF18744.1 KDO34790.1 - 0.14 12.0 0.2 0.18 11.6 0.2 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 TSNAXIP1_N PF15739.5 KDO34791.1 - 0.052 13.9 0.1 0.065 13.6 0.1 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Zea_mays_MuDR PF05928.11 KDO34791.1 - 0.14 11.8 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) AFT PF08731.11 KDO34792.1 - 0.003 18.0 5.7 3.1 8.2 0.1 3.3 3 0 0 3 3 3 2 Transcription factor AFT FAR1 PF03101.15 KDO34792.1 - 0.0034 18.0 3.6 0.43 11.3 0.3 2.7 3 0 0 3 3 3 2 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.15 KDO34792.1 - 0.28 11.2 6.0 15 5.7 0.2 3.7 3 1 0 3 3 3 0 MuDR family transposase LRR_6 PF13516.6 KDO34793.1 - 4.1e-16 57.6 21.6 0.0004 20.2 1.0 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KDO34793.1 - 4.1e-05 23.8 15.8 1.6 9.3 3.7 5.6 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KDO34793.1 - 0.00041 20.5 4.3 12 6.9 0.1 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 KDO34793.1 - 0.0058 16.4 22.4 4.8 7.0 0.0 6.2 4 3 1 5 5 5 3 Leucine rich repeat ABC_tran PF00005.27 KDO34794.1 - 6.3e-28 98.0 0.0 4.3e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO34794.1 - 1.9e-24 86.8 14.6 7.8e-13 48.7 3.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region Mg_chelatase PF01078.21 KDO34794.1 - 0.092 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MIB_HERC2 PF06701.13 KDO34795.1 - 7.4e-21 74.2 6.3 1.3e-20 73.4 6.3 1.4 1 0 0 1 1 1 1 Mib_herc2 HECT PF00632.25 KDO34796.1 - 2.4e-48 165.2 0.0 4.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 KDO34796.1 - 1.8e-10 40.5 7.1 1.8e-10 40.5 7.1 3.4 3 0 0 3 3 3 2 Zinc finger, ZZ type zf-RanBP PF00641.18 KDO34796.1 - 0.0011 18.2 25.9 0.0026 17.0 9.5 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others LRR_4 PF12799.7 KDO34797.1 - 6.6e-08 32.7 1.1 0.33 11.4 0.1 4.7 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KDO34797.1 - 3.1e-05 23.7 10.5 1.2 9.4 0.0 7.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 KDO34797.1 - 0.0071 16.7 5.4 1e+02 4.1 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Sugar_tr PF00083.24 KDO34798.1 - 1.6e-33 116.3 17.6 4.1e-33 114.9 17.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO34798.1 - 2.3e-10 39.9 39.3 7.5e-05 21.8 18.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Defensin_propep PF00879.18 KDO34798.1 - 0.61 10.4 4.1 0.62 10.4 0.1 2.7 2 0 0 2 2 2 0 Defensin propeptide PH_6 PF15406.6 KDO34801.1 - 0.0056 17.0 0.1 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 KDO34801.1 - 0.032 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 PH domain RP-C_C PF11800.8 KDO34803.1 - 0.028 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Methyltransf_31 PF13847.6 KDO34803.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pox_G9-A16 PF03003.16 KDO34805.1 - 9.8 5.9 9.1 1.8 8.3 0.7 2.2 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 NTP_transf_2 PF01909.23 KDO34806.1 - 3.1e-10 40.2 0.0 6.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KDO34806.1 - 4.7e-05 23.5 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 KDO34806.1 - 0.022 15.0 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Polbeta PF18765.1 KDO34806.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Methyltr_RsmB-F PF01189.17 KDO34807.1 - 1.9e-19 70.1 0.0 1.1e-18 67.6 0.0 2.2 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F EF-hand_1 PF00036.32 KDO34810.1 - 2.1e-11 42.5 7.6 0.0026 17.2 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO34810.1 - 8.1e-10 37.8 2.6 0.011 15.6 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KDO34810.1 - 1.7e-09 38.0 4.7 0.0026 18.2 4.4 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO34810.1 - 0.00011 21.5 2.7 0.2 11.2 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO34810.1 - 0.00022 21.0 8.2 0.45 10.4 2.3 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_11 PF08976.11 KDO34810.1 - 0.041 14.8 1.9 0.7 10.8 0.3 2.4 1 1 1 2 2 2 0 EF-hand domain YqzH PF14164.6 KDO34810.1 - 0.081 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 YqzH-like protein EF-hand_7 PF13499.6 KDO34811.1 - 1.6e-12 47.7 2.7 4.7e-08 33.4 1.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KDO34811.1 - 2.3e-12 45.5 10.6 2.4e-05 23.5 1.3 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KDO34811.1 - 1.2e-10 40.4 3.8 0.0025 17.6 0.9 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KDO34811.1 - 1.1e-08 34.1 4.2 0.0013 18.1 1.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KDO34811.1 - 2.6e-05 24.0 11.2 0.12 12.2 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair GDP_Man_Dehyd PF16363.5 KDO34812.1 - 1.7e-50 172.3 0.0 1.1e-49 169.6 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KDO34812.1 - 1.5e-45 155.5 0.0 2e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KDO34812.1 - 1.6e-08 33.9 0.0 2.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KDO34812.1 - 1.2e-07 31.1 0.0 0.0061 15.7 0.0 2.9 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KDO34812.1 - 1.3e-07 31.1 0.3 0.016 14.4 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KDO34812.1 - 3.7e-07 29.5 0.0 4.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KDO34812.1 - 0.00033 20.2 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KDO34812.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 KR domain UDPG_MGDP_dh_N PF03721.14 KDO34812.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PP2C PF00481.21 KDO34813.1 - 1.6e-74 250.8 0.5 2.1e-74 250.4 0.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KDO34813.1 - 2e-06 27.6 0.0 4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KDO34813.1 - 0.0019 18.1 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) EF1G PF00647.19 KDO34814.1 - 8.5e-37 125.5 0.8 1.8e-36 124.4 0.8 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KDO34814.1 - 1.5e-14 54.0 0.0 3.4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KDO34814.1 - 9.3e-08 32.0 0.1 1.9e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KDO34814.1 - 2.5e-07 30.8 0.0 6.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KDO34814.1 - 2.7e-06 27.6 3.2 1.3e-05 25.4 0.2 3.1 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KDO34814.1 - 0.0023 17.7 0.1 0.0042 16.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KDO34814.1 - 0.025 14.9 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SHNi-TPR PF10516.9 KDO34814.1 - 0.17 11.4 0.1 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 SHNi-TPR Tctex-1 PF03645.13 KDO34814.1 - 0.82 9.9 5.4 1.2 9.5 1.4 2.6 2 1 0 2 2 2 0 Tctex-1 family SCAN PF02023.17 KDO34815.1 - 0.021 14.6 1.1 0.42 10.4 0.1 2.7 2 1 1 3 3 3 0 SCAN domain DUF4326 PF14216.6 KDO34815.1 - 0.2 12.4 1.3 17 6.2 0.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4326) DUF4207 PF13904.6 KDO34815.1 - 1.2 8.8 15.7 1.2 8.7 4.9 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4207) DUSP PF06337.12 KDO34816.1 - 1.5e-12 47.9 0.0 3.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 DUSP domain PX PF00787.24 KDO34816.1 - 7.2e-08 32.4 1.3 1.3e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 PX domain IQ PF00612.27 KDO34816.1 - 0.033 14.0 0.2 0.033 14.0 0.2 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif GTP_CH_N PF12471.8 KDO34817.1 - 1.1e-79 266.8 0.0 3e-79 265.3 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KDO34817.1 - 1e-16 61.0 0.0 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Hyccin PF09790.9 KDO34817.1 - 0.13 11.3 0.3 0.19 10.8 0.3 1.2 1 0 0 1 1 1 0 Hyccin Lyase_1 PF00206.20 KDO34818.1 - 3e-22 79.4 0.0 4.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KDO34818.1 - 1.6e-19 70.2 0.1 4.7e-19 68.7 0.1 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus CAP59_mtransfer PF11735.8 KDO34819.1 - 1.4e-57 195.2 0.0 1.8e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 YmcE_antitoxin PF15939.5 KDO34819.1 - 0.054 13.6 0.0 8 6.7 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system Pkinase_Tyr PF07714.17 KDO34822.1 - 1.6e-27 96.5 0.0 2.4e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34822.1 - 5.2e-17 62.1 0.0 2.5e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 KDO34823.1 - 5.3e-29 97.6 12.1 7.4e-07 28.3 0.1 5.9 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KDO34823.1 - 5.5e-26 90.8 20.7 1.3e-08 35.2 0.2 4.8 2 2 5 7 7 7 6 EF-hand domain pair EF-hand_6 PF13405.6 KDO34823.1 - 2e-25 86.5 17.0 3.8e-06 26.4 0.1 6.1 6 0 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 KDO34823.1 - 2.7e-23 81.5 11.5 2.9e-05 23.8 0.2 5.4 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KDO34823.1 - 2.8e-23 80.3 16.6 0.00027 20.3 0.1 6.0 6 0 0 6 6 6 5 EF hand Caleosin PF05042.13 KDO34823.1 - 1.2e-06 28.6 1.2 0.046 13.7 0.1 3.7 3 1 1 4 4 4 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 KDO34823.1 - 0.0042 17.4 0.0 6.8 7.1 0.0 3.4 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KDO34823.1 - 0.0054 17.0 0.1 7.3 7.0 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_4 PF12763.7 KDO34823.1 - 0.013 15.5 1.2 2.6 8.0 0.2 3.5 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand UcrQ PF02939.16 KDO34823.1 - 0.051 13.5 0.1 0.096 12.6 0.1 1.3 1 0 0 1 1 1 0 UcrQ family Ank_2 PF12796.7 KDO34824.1 - 7.9e-24 84.1 1.5 1.3e-12 48.2 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO34824.1 - 4.1e-19 68.4 2.9 1.4e-05 25.3 0.2 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO34824.1 - 4.1e-18 64.9 2.3 0.0049 17.3 0.1 5.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KDO34824.1 - 3.5e-17 60.7 0.3 0.00097 19.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KDO34824.1 - 6.6e-17 61.7 0.9 4.4e-06 27.1 0.2 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) FYVE PF01363.21 KDO34824.1 - 6.7e-15 55.0 14.4 1.1e-14 54.3 14.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger ER_lumen_recept PF00810.18 KDO34825.1 - 5.5e-33 114.9 8.5 7.4e-33 114.4 5.8 2.0 2 0 0 2 2 2 1 ER lumen protein retaining receptor Malic_M PF03949.15 KDO34826.1 - 3.9e-93 311.4 0.2 4.8e-93 311.1 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KDO34826.1 - 3.7e-76 255.0 0.0 5.8e-76 254.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DnaJ_C PF01556.18 KDO34827.1 - 8.2e-32 110.3 0.1 1.1e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KDO34827.1 - 7.2e-26 90.1 0.3 1.2e-25 89.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KDO34827.1 - 7.3e-15 55.1 21.7 1.1e-14 54.5 21.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KDO34827.1 - 7.6e-06 25.8 11.1 0.0073 16.3 1.2 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KDO34827.1 - 0.023 14.4 1.1 0.023 14.4 1.1 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 KDO34827.1 - 0.023 14.7 12.3 0.54 10.3 3.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KDO34827.1 - 0.08 13.3 14.6 5.3 7.5 0.3 4.1 1 1 3 4 4 4 0 Restriction alleviation protein Lar DUF2933 PF11666.8 KDO34827.1 - 0.38 10.8 9.2 0.82 9.8 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) zinc-ribbons_6 PF07191.12 KDO34827.1 - 2.9 8.0 10.0 15 5.7 10.0 1.9 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KDO34827.1 - 3.7 7.6 12.1 11 6.1 12.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.18 KDO34827.1 - 4.7 7.1 17.0 5.2 7.0 0.3 4.0 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Pkinase PF00069.25 KDO34828.1 - 3.9e-63 213.3 0.0 5.5e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34828.1 - 4.4e-31 108.1 0.0 7.8e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO34828.1 - 3.4e-11 43.6 0.1 7.6e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 PH domain SnoaL_2 PF12680.7 KDO34828.1 - 0.0026 18.4 0.1 0.0066 17.1 0.1 1.8 1 0 0 1 1 1 1 SnoaL-like domain PH_11 PF15413.6 KDO34828.1 - 0.0026 18.1 1.3 0.069 13.6 1.3 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 KDO34828.1 - 0.0027 16.7 0.1 0.0057 15.6 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH_8 PF15409.6 KDO34828.1 - 0.0049 17.1 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 KDO34828.1 - 0.015 14.6 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KDO34829.1 - 2.7e-68 230.2 0.0 3.6e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34829.1 - 3.8e-31 108.3 0.0 5.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KDO34829.1 - 6e-11 42.8 0.1 2.6e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KDO34829.1 - 0.00021 21.7 2.1 0.0078 16.6 2.1 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 KDO34829.1 - 0.0015 17.6 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KDO34829.1 - 0.015 14.7 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KDO34830.1 - 0.0022 17.9 0.1 0.0051 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.27 KDO34831.1 - 6e-39 133.7 0.0 2.6e-22 79.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO34831.1 - 6.9e-38 130.9 2.7 8.2e-23 81.4 0.0 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO34831.1 - 2.2e-09 37.1 0.4 0.016 14.6 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO34831.1 - 1.7e-05 25.1 0.0 0.19 12.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KDO34831.1 - 4.1e-05 22.8 0.0 0.19 10.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KDO34831.1 - 4.3e-05 24.0 0.5 0.55 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KDO34831.1 - 0.00023 21.8 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KDO34831.1 - 0.00034 20.6 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO34831.1 - 0.00035 20.3 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO34831.1 - 0.0004 20.3 0.0 0.45 10.3 0.0 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KDO34831.1 - 0.00054 20.0 0.0 0.043 13.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 KDO34831.1 - 0.0014 18.6 0.2 1.4 8.9 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KDO34831.1 - 0.0015 19.0 0.3 0.46 10.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KDO34831.1 - 0.0037 16.8 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 KDO34831.1 - 0.0045 16.6 2.5 0.38 10.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KDO34831.1 - 0.0055 16.4 0.1 3.3 7.4 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein cobW PF02492.19 KDO34831.1 - 0.0059 16.2 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KDO34831.1 - 0.006 16.7 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KDO34831.1 - 0.0069 16.1 0.2 4.1 7.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO34831.1 - 0.011 15.9 0.5 0.42 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO34831.1 - 0.018 14.2 0.0 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KDO34831.1 - 0.023 14.6 0.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 KDO34831.1 - 0.024 15.2 0.0 8.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO34831.1 - 0.026 13.8 0.0 4.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AFG1_ATPase PF03969.16 KDO34831.1 - 0.034 13.0 0.9 4.6 6.0 0.2 3.0 2 1 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.6 KDO34831.1 - 0.057 13.1 0.2 6.9 6.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KDO34831.1 - 0.063 13.2 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KDO34831.1 - 0.064 12.7 0.1 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.6 KDO34831.1 - 0.075 13.4 0.1 14 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KDO34831.1 - 0.1 13.0 0.0 17 5.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.12 KDO34831.1 - 0.11 12.3 0.3 6.3 6.7 0.1 2.7 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KDO34831.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 KDO34831.1 - 0.15 11.3 0.0 9.1 5.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.15 KDO34831.1 - 0.26 11.2 1.3 26 4.7 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.6 KDO34831.1 - 0.41 10.4 0.7 3.5 7.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KDO34831.1 - 1.1 9.2 2.7 18 5.4 0.4 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KDO34832.1 - 3.7e-47 160.3 0.0 1.9e-28 99.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO34832.1 - 5.4e-36 124.7 19.5 5.4e-28 98.4 5.6 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 KDO34832.1 - 9e-06 26.2 5.1 0.035 14.5 1.6 3.6 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.19 KDO34832.1 - 1.5e-05 24.6 6.3 0.23 10.9 0.3 4.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KDO34832.1 - 4.7e-05 23.5 0.0 0.051 13.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO34832.1 - 0.00042 20.6 0.3 1.5 9.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KDO34832.1 - 0.00059 19.6 1.7 1.5 8.5 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KDO34832.1 - 0.0009 19.2 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KDO34832.1 - 0.0016 18.3 1.2 6.1 6.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO34832.1 - 0.0022 17.7 0.1 2.4 8.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO34832.1 - 0.033 14.7 0.1 1.8 9.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO34832.1 - 0.058 13.9 0.0 5.8 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KDO34832.1 - 0.1 11.8 0.3 13 4.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KDO34832.1 - 0.15 12.1 1.7 6 6.9 0.5 2.3 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 KDO34832.1 - 0.15 12.0 0.8 5.8 6.9 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KDO34832.1 - 0.42 10.7 0.8 1.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain LRR_6 PF13516.6 KDO34833.1 - 6.4e-15 53.9 17.3 0.056 13.5 0.0 8.7 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 KDO34833.1 - 1.4e-10 41.3 14.1 0.00019 21.8 0.1 6.3 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO34833.1 - 1.4e-05 24.7 16.2 0.00026 20.7 1.4 5.8 5 2 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 KDO34833.1 - 0.0037 17.6 6.1 56 4.9 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich Repeat APG6_N PF17675.1 KDO34834.1 - 0.89 10.1 31.3 1.1 9.8 2.9 3.5 2 2 1 3 3 3 0 Apg6 coiled-coil region Goodbye PF17109.5 KDO34834.1 - 2 8.9 7.3 0.33 11.4 0.2 3.1 2 2 1 4 4 4 0 fungal STAND N-terminal Goodbye domain V_ATPase_I PF01496.19 KDO34834.1 - 5.6 4.7 20.0 0.49 8.3 14.0 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KDO34834.1 - 9.8 6.7 11.5 6.2 7.3 0.9 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AMP-binding PF00501.28 KDO34836.1 - 5.1e-88 295.5 0.0 7.1e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 KDO34837.1 - 4.8e-44 150.2 0.0 1.4e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO34837.1 - 6.2e-37 127.7 8.6 7.4e-23 81.6 1.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 KDO34837.1 - 8e-07 29.1 0.1 0.052 13.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KDO34837.1 - 1e-05 25.1 2.1 3.1 7.2 0.1 4.0 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO34837.1 - 1.2e-05 25.8 7.2 0.00046 20.6 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO34837.1 - 1.2e-05 25.4 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO34837.1 - 3.7e-05 23.4 0.1 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO34837.1 - 0.00014 22.4 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KDO34837.1 - 0.00025 21.3 0.2 0.91 9.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KDO34837.1 - 0.00038 20.4 0.0 4.3 7.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KDO34837.1 - 0.00072 19.3 0.2 0.34 10.6 0.1 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF815 PF05673.13 KDO34837.1 - 0.0022 17.2 0.1 1.9 7.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KDO34837.1 - 0.0022 18.1 0.4 0.39 10.8 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KDO34837.1 - 0.0098 15.6 0.3 0.33 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KDO34837.1 - 0.01 15.2 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KDO34837.1 - 0.015 15.5 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KDO34837.1 - 0.015 15.5 0.0 6 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KDO34837.1 - 0.054 13.2 0.0 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KDO34837.1 - 0.056 12.7 0.1 3.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 KDO34837.1 - 0.056 12.7 0.0 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 KDO34837.1 - 0.078 12.5 0.0 7 6.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KDO34837.1 - 0.089 11.8 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PRK PF00485.18 KDO34837.1 - 0.15 11.7 0.1 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KDO34837.1 - 0.17 12.3 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 KDO34837.1 - 0.22 11.1 0.0 24 4.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 KDO34838.1 - 4.5e-30 104.4 0.0 7.3e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO34838.1 - 9.7e-24 83.9 0.0 2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KDO34838.1 - 7.7e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KDO34838.1 - 7.1e-08 32.1 0.0 1.6e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KDO34838.1 - 0.00033 20.3 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KDO34838.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KDO34838.1 - 0.033 14.1 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ThiF PF00899.21 KDO34839.1 - 1.4e-21 77.0 0.0 1.9e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KDO34839.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Gemini_mov PF01708.16 KDO34840.1 - 0.034 13.9 0.3 0.049 13.4 0.3 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein Myosin_tail_1 PF01576.19 KDO34841.1 - 0.00042 18.3 14.0 0.00048 18.1 14.0 1.1 1 0 0 1 1 1 1 Myosin tail UPF0242 PF06785.11 KDO34841.1 - 0.0089 16.2 11.0 0.23 11.5 1.6 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 KDO34841.1 - 0.037 13.6 13.2 0.43 10.0 2.1 2.0 1 1 1 2 2 2 0 Leucine zipper BST2 PF16716.5 KDO34841.1 - 0.046 14.3 3.1 0.046 14.3 3.1 3.4 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 TTRAP PF14203.6 KDO34841.1 - 0.078 13.0 3.1 0.38 10.8 0.3 3.0 1 1 2 3 3 3 0 Putative tranposon-transfer assisting protein Laminin_II PF06009.12 KDO34841.1 - 0.09 12.8 7.1 0.78 9.7 0.8 2.3 1 1 1 2 2 2 0 Laminin Domain II TMF_TATA_bd PF12325.8 KDO34841.1 - 0.13 12.5 9.5 1.1 9.5 2.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Muted PF14942.6 KDO34841.1 - 0.24 11.7 6.8 0.28 11.5 6.5 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Atg14 PF10186.9 KDO34841.1 - 0.28 10.2 9.0 0.35 9.9 9.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KDO34841.1 - 0.28 11.3 4.1 0.41 10.8 3.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KDO34841.1 - 0.37 10.0 6.9 0.44 9.7 0.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.18 KDO34841.1 - 0.97 8.7 6.1 1.1 8.4 6.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 KDO34841.1 - 1 8.8 8.7 1.2 8.7 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SYCE1 PF15233.6 KDO34841.1 - 1.1 9.4 12.1 3.6 7.6 3.5 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF16 PF01519.16 KDO34841.1 - 2.1 8.9 6.7 57 4.3 6.7 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 KDO34841.1 - 2.3 8.3 13.9 1.3 9.1 0.1 3.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KDO34841.1 - 2.8 7.2 12.9 6.2 6.1 13.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FadA PF09403.10 KDO34841.1 - 2.9 8.5 10.9 1.7 9.2 3.4 3.0 1 1 2 3 3 3 0 Adhesion protein FadA ABC_tran_CTD PF16326.5 KDO34841.1 - 3.7 7.9 12.2 11 6.4 5.8 3.2 1 1 2 3 3 3 0 ABC transporter C-terminal domain FAM76 PF16046.5 KDO34841.1 - 3.8 6.8 8.5 5.7 6.2 8.5 1.4 1 1 0 1 1 1 0 FAM76 protein Filament PF00038.21 KDO34842.1 - 0.028 14.0 0.3 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein Syntaxin_2 PF14523.6 KDO34842.1 - 0.047 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Acyl-CoA_dh_2 PF08028.11 KDO34843.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 KDO34845.1 - 1.1e-85 287.9 0.0 1.7e-85 287.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO34845.1 - 0.0031 18.5 0.5 0.015 16.2 0.6 2.2 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO34847.1 - 4.1e-92 309.0 0.0 5e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KDO34848.1 - 5.4e-87 292.1 0.1 6.8e-87 291.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO34848.1 - 0.0016 19.4 2.0 0.0018 19.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KDO34849.1 - 9.6e-14 51.1 16.8 1.9e-13 50.0 16.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_28 PF02636.17 KDO34850.1 - 1.8e-73 247.4 0.0 2.1e-72 243.9 0.0 2.1 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Mpv17_PMP22 PF04117.12 KDO34851.1 - 1e-15 57.7 1.3 1.7e-15 57.0 1.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Trep_Strep PF09605.10 KDO34851.1 - 0.047 13.7 0.4 0.093 12.7 0.1 1.6 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Voltage_CLC PF00654.20 KDO34852.1 - 5.6e-54 183.7 34.0 5.6e-54 183.7 34.0 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KDO34852.1 - 7e-09 36.0 5.0 1.7e-06 28.4 0.2 3.2 3 0 0 3 3 3 2 CBS domain Tautomerase PF01361.21 KDO34854.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme TTL PF03133.15 KDO34855.1 - 6.5e-82 275.0 0.0 8.8e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KDO34855.1 - 1.9e-07 30.6 0.0 0.00019 20.8 0.0 3.3 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KDO34855.1 - 0.0028 16.9 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KDO34855.1 - 0.19 11.8 0.0 5.5 7.0 0.0 2.8 2 1 0 2 2 2 0 ATP-grasp domain DUF4506 PF14958.6 KDO34856.1 - 1.2e-07 31.4 0.0 2.2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4506) Lectin_N PF03954.14 KDO34856.1 - 0.21 11.4 2.3 0.42 10.3 2.3 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ank_5 PF13857.6 KDO34857.1 - 0.01 16.1 0.2 0.023 15.0 0.2 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 KDO34857.1 - 0.026 15.0 0.2 0.059 13.8 0.2 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 KDO34857.1 - 0.085 13.5 0.0 0.34 11.6 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 KDO34857.1 - 0.093 13.3 0.1 0.18 12.4 0.1 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) KIAA1430 PF13879.6 KDO34858.1 - 4.7e-19 69.1 0.9 1.2e-18 67.8 0.9 1.7 1 0 0 1 1 1 1 KIAA1430 homologue RPAP1_N PF08621.10 KDO34858.1 - 0.84 9.5 4.0 7 6.5 0.1 3.1 3 0 0 3 3 3 0 RPAP1-like, N-terminal GPI-anchored PF10342.9 KDO34859.1 - 0.00012 22.8 0.0 0.00015 22.5 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PNP_UDP_1 PF01048.20 KDO34861.1 - 1.8e-24 86.3 0.0 2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DEAD PF00270.29 KDO34862.1 - 1.3e-45 155.3 0.1 2.3e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO34862.1 - 5e-32 110.5 0.3 4.7e-31 107.4 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO34862.1 - 7e-06 26.1 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KDO34862.1 - 0.00018 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO34862.1 - 0.002 18.5 0.4 0.029 14.7 0.2 2.3 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 KDO34862.1 - 0.0052 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KDO34862.1 - 0.026 13.3 0.1 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 KDO34862.1 - 0.099 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 KDO34862.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 KDO34862.1 - 0.13 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.25 KDO34862.1 - 0.16 11.2 0.0 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Hydrolase_4 PF12146.8 KDO34863.1 - 8.3e-13 48.1 2.2 6.9e-07 28.8 0.5 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO34863.1 - 1.7e-07 32.1 10.4 7.8e-07 29.9 4.1 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KDO34863.1 - 4.9e-07 29.7 0.5 0.00053 19.7 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KDO34863.1 - 1e-06 28.7 0.1 0.0074 16.1 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KDO34863.1 - 4.2e-05 23.1 0.1 7.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KDO34863.1 - 0.00018 21.4 0.2 0.00029 20.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KDO34863.1 - 0.00022 20.6 0.1 0.0083 15.5 0.0 2.1 1 1 1 2 2 2 1 Secretory lipase FSH1 PF03959.13 KDO34863.1 - 0.0013 18.5 0.0 0.0043 16.7 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 KDO34863.1 - 0.031 13.8 0.0 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LIDHydrolase PF10230.9 KDO34863.1 - 0.035 13.6 0.1 1.2 8.6 0.0 2.0 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase RMMBL PF07521.12 KDO34863.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Erg28 PF03694.13 KDO34864.1 - 0.00012 22.4 2.3 0.00018 21.8 1.8 1.5 1 1 0 1 1 1 1 Erg28 like protein PCO_ADO PF07847.12 KDO34865.1 - 4.3e-13 49.2 0.1 6.4e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 PCO_ADO PCO_ADO PF07847.12 KDO34866.1 - 7.5e-06 25.5 0.0 7.5e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 PCO_ADO Voltage_CLC PF00654.20 KDO34869.1 - 1.9e-71 241.2 26.1 1.9e-71 241.2 26.1 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel GCIP PF13324.6 KDO34870.1 - 4.1e-25 88.9 0.2 5.8e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting zf-C3HC4_2 PF13923.6 KDO34871.1 - 2.8e-07 30.3 8.8 2.8e-07 30.3 8.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO34871.1 - 4.8e-07 29.5 8.4 4.8e-07 29.5 8.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KDO34871.1 - 3.8e-06 26.7 6.0 3.8e-06 26.7 6.0 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RanBP PF00641.18 KDO34871.1 - 1.7e-05 24.0 1.3 1.7e-05 24.0 1.3 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_UBOX PF13445.6 KDO34871.1 - 2.2e-05 24.4 6.6 3.8e-05 23.6 5.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KDO34871.1 - 3.2e-05 24.2 9.4 3.2e-05 24.2 9.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KDO34871.1 - 0.00011 22.3 8.8 0.00011 22.3 8.8 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KDO34871.1 - 0.00042 20.2 10.6 0.00042 20.2 10.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KDO34871.1 - 0.0011 19.0 5.9 0.0011 19.0 5.9 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KDO34871.1 - 0.0034 17.2 12.5 0.0034 17.2 12.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KDO34871.1 - 0.019 14.8 2.0 0.052 13.4 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KDO34871.1 - 0.36 10.6 11.5 2.7 7.8 6.2 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KDO34871.1 - 2.5 8.5 10.7 0.28 11.5 5.4 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KDO34871.1 - 3.4 7.9 13.5 0.12 12.6 7.0 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KDO34871.1 - 7.8 6.6 17.6 13 5.9 0.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon ABC_membrane PF00664.23 KDO34872.1 - 1.1e-58 199.1 18.9 4.7e-32 111.7 4.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KDO34872.1 - 1.3e-47 161.7 0.0 4e-26 92.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KDO34872.1 - 5.3e-08 32.6 5.2 0.00085 18.8 0.3 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO34872.1 - 1.9e-06 28.4 0.9 0.0082 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KDO34872.1 - 2.1e-05 24.6 0.1 0.25 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KDO34872.1 - 0.00015 21.5 1.6 0.043 13.6 0.1 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO34872.1 - 0.00019 21.8 0.2 1.3 9.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KDO34872.1 - 0.00029 20.8 0.2 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KDO34872.1 - 0.00062 19.9 0.5 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_21 PF13304.6 KDO34872.1 - 0.012 15.4 0.3 3 7.6 0.0 3.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KDO34872.1 - 0.019 14.3 0.6 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 KDO34872.1 - 0.022 15.3 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KDO34872.1 - 0.037 13.8 0.3 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 KDO34872.1 - 0.042 13.4 0.2 11 5.5 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF87 PF01935.17 KDO34872.1 - 0.055 13.6 0.4 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KDO34872.1 - 0.084 12.6 5.0 2.6 7.7 0.0 3.4 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KDO34872.1 - 0.12 11.6 0.3 4 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KDO34872.1 - 0.14 11.7 2.8 5.4 6.6 0.1 3.2 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KDO34872.1 - 0.14 12.0 0.2 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KDO34872.1 - 0.16 11.1 0.6 4.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KDO34872.1 - 0.21 11.1 0.8 1.4 8.5 0.1 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MFS_MOT1 PF16983.5 KDO34872.1 - 0.34 11.3 6.2 0.15 12.5 0.8 3.2 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily TIMELESS PF04821.14 KDO34873.1 - 3.1e-58 197.2 1.3 6.2e-58 196.3 1.3 1.5 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KDO34873.1 - 4.6e-08 32.7 0.1 4.6e-08 32.7 0.1 4.0 4 0 0 4 4 4 1 Timeless protein C terminal region DUF4746 PF15928.5 KDO34873.1 - 0.0093 15.4 0.3 0.0093 15.4 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) SpmSyn_N PF17950.1 KDO34873.1 - 0.057 13.6 0.2 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal FAM176 PF14851.6 KDO34873.1 - 0.058 13.1 15.3 0.1 12.2 3.4 3.1 2 0 0 2 2 2 0 FAM176 family DUF913 PF06025.12 KDO34873.1 - 0.38 9.7 4.7 0.063 12.2 0.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TLP-20 PF06088.11 KDO34873.1 - 0.82 9.5 11.2 3.2 7.6 3.3 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Mis14 PF08641.12 KDO34873.1 - 8.5 6.7 14.1 0.99 9.7 5.7 2.6 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Glyco_hydro_72 PF03198.14 KDO34874.1 - 4.9e-54 183.7 0.1 6.4e-54 183.3 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KDO34874.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.5 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_2 PF13347.6 KDO34875.1 - 1.3e-06 27.3 9.0 1.3e-06 27.3 9.0 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein DUF2545 PF10810.8 KDO34875.1 - 0.031 14.4 1.3 0.031 14.4 1.3 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2545) IL15 PF02372.15 KDO34875.1 - 0.039 14.0 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 Interleukin 15 Fringe PF02434.16 KDO34876.1 - 2.5e-05 23.8 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Pkinase_Tyr PF07714.17 KDO34877.1 - 2.3e-42 145.1 0.0 2.8e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34877.1 - 3.2e-39 134.9 0.0 4.5e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_1b PF00579.25 KDO34878.1 - 1.4e-76 257.7 0.0 1.8e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 KDO34878.1 - 0.00011 21.9 0.4 0.00019 21.1 0.4 1.4 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 KDO34878.1 - 0.0034 17.2 0.2 0.89 9.4 0.1 2.3 1 1 1 2 2 2 2 Tyrosyl-tRNA synthetase C-terminal domain Acetyltransf_6 PF13480.7 KDO34878.1 - 0.18 12.0 1.0 0.41 10.8 0.1 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Ric8 PF10165.9 KDO34879.1 - 6.2e-27 94.7 2.6 8.3e-27 94.3 2.6 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn LRR_6 PF13516.6 KDO34880.1 - 2.4e-17 61.4 24.1 0.082 13.0 0.3 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 KDO34880.1 - 1.9e-13 50.4 17.9 6.6e-05 23.2 0.0 6.1 4 1 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO34880.1 - 1.4e-05 24.7 7.3 0.082 12.7 0.0 4.9 2 1 3 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KDO34880.1 - 7e-05 22.9 23.8 2 9.3 0.1 9.7 11 1 0 11 11 11 2 Leucine Rich Repeat SelB-wing_2 PF09106.11 KDO34880.1 - 0.019 15.2 0.1 0.065 13.4 0.1 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix TFIIE_alpha PF02002.17 KDO34880.1 - 0.098 12.5 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 TFIIE alpha subunit COPIIcoated_ERV PF07970.12 KDO34883.1 - 2.8e-42 145.1 0.1 3.9e-42 144.6 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KDO34883.1 - 2.7e-19 69.3 0.2 5.5e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-BED PF02892.15 KDO34884.1 - 0.00016 21.6 2.8 1.2 9.2 0.4 3.3 3 0 0 3 3 3 2 BED zinc finger zf-UDP PF14569.6 KDO34884.1 - 0.079 13.1 0.6 3.4 7.8 0.1 2.9 2 0 0 2 2 2 0 Zinc-binding RING-finger Ist1 PF03398.14 KDO34885.1 - 2.4e-60 203.2 3.0 2.9e-60 202.9 3.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway CcmE PF03100.15 KDO34885.1 - 0.16 12.0 0.1 0.39 10.7 0.0 1.6 1 1 1 2 2 2 0 CcmE AHH PF14412.6 KDO34886.1 - 0.025 14.7 1.5 0.025 14.7 1.5 1.5 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF1840 PF08895.11 KDO34886.1 - 0.057 13.8 1.2 0.09 13.1 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) LRR_4 PF12799.7 KDO34887.1 - 7.2e-06 26.3 2.8 2.8e-05 24.4 0.5 2.9 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO34887.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 KDO34887.1 - 1.9 8.3 6.7 0.71 9.7 0.4 2.7 2 1 0 2 2 2 0 Leucine rich repeat DnaJ PF00226.31 KDO34888.1 - 1.2e-12 47.7 0.2 2.6e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DMSP_lyase PF16867.5 KDO34888.1 - 0.00071 19.3 0.3 0.0024 17.6 0.0 1.9 2 1 0 2 2 2 1 Dimethlysulfonioproprionate lyase SBDS_C PF09377.10 KDO34888.1 - 0.14 12.1 0.1 0.18 11.8 0.1 1.3 1 1 0 1 1 1 0 SBDS protein C-terminal domain Pneumo_att_G PF05539.11 KDO34888.1 - 0.22 11.1 1.3 0.25 10.9 1.3 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Globin PF00042.22 KDO34889.1 - 0.0028 18.2 0.3 0.012 16.2 0.3 2.0 1 1 0 1 1 1 1 Globin Pkinase_Tyr PF07714.17 KDO34891.1 - 1.3e-44 152.4 0.0 1.8e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34891.1 - 5.3e-39 134.2 0.0 8.7e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO34891.1 - 0.0094 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO34891.1 - 0.22 10.2 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L34 PF00468.17 KDO34892.1 - 0.067 13.2 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L34 FYVE PF01363.21 KDO34893.1 - 7.6e-19 67.6 7.6 1.3e-18 66.9 7.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KDO34893.1 - 0.0012 19.0 5.2 0.0018 18.4 5.2 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger zf_C2HC_14 PF18574.1 KDO34893.1 - 0.021 14.6 1.8 0.047 13.5 1.8 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain AKAP95 PF04988.12 KDO34893.1 - 0.094 12.9 0.5 0.13 12.5 0.5 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Siva PF05458.12 KDO34893.1 - 0.47 10.1 7.2 0.7 9.5 7.2 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DZR PF12773.7 KDO34893.1 - 1.3 9.1 10.8 57 3.8 10.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon Pkinase_Tyr PF07714.17 KDO34894.1 - 3e-44 151.3 0.0 4e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34894.1 - 9.5e-38 130.1 0.0 1.4e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO34894.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO34894.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 KDO34895.1 - 1.1e-17 64.1 1.7 0.00029 21.6 0.2 8.5 8 0 0 8 8 8 4 WD domain, G-beta repeat C2 PF00168.30 KDO34895.1 - 2e-09 37.6 0.0 8.5e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain ANAPC4_WD40 PF12894.7 KDO34895.1 - 0.00054 20.2 0.0 0.26 11.6 0.0 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Aa_trans PF01490.18 KDO34896.1 - 5.5e-33 114.3 25.1 7.6e-33 113.8 25.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein C2 PF00168.30 KDO34897.1 - 2.3e-18 66.4 0.0 4.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.11 KDO34897.1 - 0.0093 15.0 1.1 0.014 14.4 1.1 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin C2 PF00168.30 KDO34898.1 - 1.1e-21 77.0 0.0 6.3e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 C2 domain Pex24p PF06398.11 KDO34898.1 - 0.0041 16.1 3.9 0.0045 16.0 3.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Sel1 PF08238.12 KDO34899.1 - 1.1e-10 41.8 31.6 1.6e-05 25.4 0.3 7.4 7 1 0 7 7 7 4 Sel1 repeat TPR_6 PF13174.6 KDO34899.1 - 0.79 10.5 17.1 37 5.3 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 KDO34900.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box PF00646.33 KDO34900.1 - 0.00061 19.6 0.3 0.0012 18.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KDO34900.1 - 0.016 15.1 1.4 0.037 13.9 1.4 1.7 1 0 0 1 1 1 0 F-box-like Aa_trans PF01490.18 KDO34901.1 - 2.4e-60 204.4 16.7 2.8e-60 204.2 16.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO34901.1 - 1.1e-07 31.3 1.2 1.1e-07 31.3 1.2 2.2 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family DUF1240 PF06836.12 KDO34901.1 - 1.3 9.5 4.7 0.64 10.6 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) RR_TM4-6 PF06459.12 KDO34902.1 - 2.2 8.0 7.7 3.1 7.5 7.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 His_Phos_2 PF00328.22 KDO34903.1 - 1.7e-13 50.7 0.1 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) bZIP_2 PF07716.15 KDO34904.1 - 0.0034 17.4 0.5 0.0034 17.4 0.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper Ank_2 PF12796.7 KDO34905.1 - 1.8e-17 63.7 2.7 2.4e-11 44.1 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34905.1 - 6.2e-13 49.0 0.6 2.4e-12 47.1 0.3 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO34905.1 - 1.3e-11 44.5 2.2 1.3e-06 28.5 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO34905.1 - 7.6e-10 38.8 7.9 1.4e-05 25.4 0.1 3.8 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KDO34905.1 - 5e-08 32.6 2.2 0.00088 19.6 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Biopterin_H PF00351.21 KDO34906.1 - 1.6e-149 497.4 0.0 2.1e-149 497.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KDO34906.1 - 2.3e-05 24.1 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain Ank_2 PF12796.7 KDO34908.1 - 2.3e-21 76.1 5.5 2.7e-06 27.9 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO34908.1 - 1.6e-19 67.9 17.7 0.045 14.3 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KDO34908.1 - 9.5e-16 58.0 11.8 0.00051 20.5 0.0 6.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KDO34908.1 - 1.3e-12 47.6 14.2 0.35 11.4 0.0 8.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KDO34908.1 - 4.2e-09 36.5 7.1 0.048 14.0 0.1 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Pkinase PF00069.25 KDO34908.1 - 4.7e-07 29.4 0.0 8.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KDO34908.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Phage_T7_tail PF03906.14 KDO34909.1 - 0.00031 20.4 0.1 0.00042 20.0 0.1 1.1 1 0 0 1 1 1 1 Phage T7 tail fibre protein DUF1640 PF07798.11 KDO34910.1 - 0.00016 21.8 28.3 0.073 13.1 1.1 5.6 3 2 1 4 4 4 2 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 KDO34910.1 - 0.00029 20.9 26.0 0.13 12.3 1.6 6.0 1 1 4 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus FAM117 PF15388.6 KDO34910.1 - 0.27 10.6 2.7 2.8 7.3 0.2 2.7 3 0 0 3 3 3 0 Protein Family FAM117 Bacillus_HBL PF05791.11 KDO34910.1 - 0.57 10.0 7.4 24 4.7 0.0 4.2 4 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) CdvA PF18822.1 KDO34910.1 - 1 9.2 10.5 0.54 10.1 0.1 4.2 5 2 0 5 5 5 0 CdvA-like coiled-coil domain DUF1848 PF08902.11 KDO34910.1 - 1.5 8.5 3.6 2 8.0 0.0 2.7 2 2 1 3 3 3 0 Domain of unknown function (DUF1848) HIP1_clath_bdg PF16515.5 KDO34910.1 - 8.8 7.0 25.6 0.43 11.2 2.3 5.5 2 1 2 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LsmAD PF06741.13 KDO34911.1 - 5.4e-25 87.7 3.7 5.4e-25 87.7 3.7 1.7 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KDO34911.1 - 2.4e-13 50.0 0.0 6.7e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 KDO34911.1 - 8.9e-05 22.5 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Gemin7 PF11095.8 KDO34911.1 - 0.00074 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) PAM2 PF07145.15 KDO34911.1 - 0.001 18.6 2.4 0.29 10.9 0.2 2.7 1 1 1 2 2 2 2 Ataxin-2 C-terminal region LPP20 PF02169.16 KDO34911.1 - 0.021 15.2 0.9 0.039 14.3 0.9 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein DUF150_C PF17384.2 KDO34911.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain LSM PF01423.22 KDO34911.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 LSM domain Gemin6 PF06372.12 KDO34911.1 - 0.13 11.8 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Gemin6 protein MMR_HSR1 PF01926.23 KDO34912.1 - 2.7e-14 53.2 0.0 2.2e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KDO34912.1 - 2.5e-06 27.5 0.0 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KDO34912.1 - 4.4e-06 26.3 0.1 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KDO34912.1 - 0.00055 20.0 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 Dynamin family PolC_DP2 PF03833.13 KDO34912.1 - 0.023 12.6 0.8 0.034 12.0 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 KDO34912.1 - 0.56 10.4 7.4 1.5 9.0 7.4 1.7 1 1 0 1 1 1 0 B-box zinc finger Stig1 PF04885.13 KDO34912.1 - 2.3 8.7 7.9 0.14 12.7 2.5 1.7 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Crust_neurohorm PF01147.17 KDO34912.1 - 2.5 8.0 5.8 0.25 11.2 0.8 1.9 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family cNMP_binding PF00027.29 KDO34914.1 - 2.9e-28 97.8 0.0 5.3e-12 45.6 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO34914.1 - 2.5e-15 56.4 41.5 1.2e-10 41.1 3.7 3.2 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 KDO34914.1 - 0.00046 20.1 7.2 0.00046 20.1 7.2 3.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KDO34915.1 - 5.9e-11 42.1 9.5 9.4e-11 41.4 9.5 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KDO34915.1 - 3.9e-06 26.8 0.1 8e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KDO34915.1 - 0.019 14.9 3.0 0.019 14.9 3.0 2.3 2 0 0 2 2 2 0 Ion channel CtaG_Cox11 PF04442.14 KDO34916.1 - 3.4e-61 205.7 0.0 4.9e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Proteasome PF00227.26 KDO34917.1 - 4.4e-26 91.5 0.2 1.1e-25 90.3 0.2 1.5 1 1 0 1 1 1 1 Proteasome subunit cNMP_binding PF00027.29 KDO34918.1 - 4.6e-38 129.2 0.3 1.4e-18 66.7 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DUF5586 PF17824.1 KDO34918.1 - 0.00054 19.2 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) ATP-synt_DE_N PF02823.16 KDO34918.1 - 0.0051 16.7 0.0 4.6 7.2 0.0 2.5 2 0 0 2 2 2 2 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF5044 PF16447.5 KDO34918.1 - 0.011 15.5 0.1 0.33 10.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5044) MAM33 PF02330.16 KDO34918.1 - 0.013 15.5 0.7 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein EF-hand_14 PF17959.1 KDO34918.1 - 0.026 14.9 0.2 7 7.1 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Dpy-30 PF05186.13 KDO34918.1 - 0.15 11.8 0.3 0.83 9.4 0.2 2.3 2 1 0 2 2 2 0 Dpy-30 motif Ank_3 PF13606.6 KDO34919.1 - 8.5e-22 74.9 3.9 0.00014 22.0 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KDO34919.1 - 7.8e-21 74.5 3.2 1.1e-11 45.1 0.4 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO34919.1 - 2.7e-19 69.2 4.0 4.4e-10 39.9 0.6 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO34919.1 - 4.1e-16 58.6 10.1 6.1e-06 26.4 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KDO34919.1 - 8.6e-12 45.1 8.7 0.0016 18.7 0.1 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) CAMSAP_CC1 PF17095.5 KDO34919.1 - 0.02 14.7 0.2 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin eIF_4EBP PF05456.11 KDO34919.1 - 0.065 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RTBV_P46 PF06216.11 KDO34919.1 - 0.082 11.8 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein CENP-Q PF13094.6 KDO34919.1 - 0.33 11.1 6.6 0.77 9.9 6.0 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 KDO34919.1 - 0.46 9.5 2.8 0.75 8.8 2.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4763 PF15960.5 KDO34919.1 - 0.61 9.3 3.4 0.93 8.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TMF_DNA_bd PF12329.8 KDO34919.1 - 0.63 10.1 6.8 1.3 9.1 4.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF676 PF05057.14 KDO34921.1 - 3e-14 53.1 0.0 5.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_1 PF00515.28 KDO34921.1 - 1.2e-08 34.4 4.5 0.15 11.9 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34921.1 - 1.8e-08 33.9 20.6 0.23 11.7 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KDO34921.1 - 2.7e-08 34.0 37.7 0.00021 21.5 2.4 6.0 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 KDO34921.1 - 7.4e-05 22.5 24.5 0.051 13.5 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34921.1 - 0.0031 17.6 7.5 1.1 9.7 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KDO34921.1 - 0.0039 17.8 4.7 0.011 16.4 4.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPR_4 PF07721.14 KDO34921.1 - 0.012 16.1 0.6 0.012 16.1 0.6 5.5 5 0 0 5 5 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KDO34921.1 - 0.042 13.5 1.2 1.6 8.4 0.3 3.2 2 1 0 2 2 2 0 26S proteasome subunit RPN7 PilP PF04351.13 KDO34921.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilP TPR_7 PF13176.6 KDO34921.1 - 0.36 10.9 14.2 1 9.5 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF410 PF04190.13 KDO34921.1 - 0.53 10.0 5.7 0.93 9.2 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF410) TPR_16 PF13432.6 KDO34921.1 - 0.97 10.1 30.7 0.79 10.4 1.3 6.2 3 3 2 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 KDO34922.1 - 2e-48 164.4 0.0 5.8e-48 163.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO34922.1 - 1.2e-33 115.8 0.0 5.7e-33 113.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO34922.1 - 6.6e-05 23.0 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KDO34922.1 - 0.0009 18.5 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase IRK_C PF17655.1 KDO34923.1 - 2.4e-21 76.1 0.2 2.2e-15 56.7 0.0 2.8 2 1 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 KDO34923.1 - 3.2e-10 39.8 20.9 4.3e-05 23.4 8.0 2.7 2 0 0 2 2 2 2 Ion channel IRK PF01007.20 KDO34923.1 - 2.3e-09 37.2 12.7 0.0005 19.9 1.7 3.8 2 2 1 3 3 3 3 Inward rectifier potassium channel transmembrane domain TPT PF03151.16 KDO34924.1 - 1.1e-05 25.0 4.9 0.025 13.9 0.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KDO34924.1 - 2.7e-05 24.3 23.8 0.0014 18.9 4.9 3.3 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KDO34924.1 - 0.0032 16.7 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KDO34924.1 - 0.037 13.2 0.2 0.037 13.2 0.2 2.5 3 0 0 3 3 3 0 UAA transporter family cNMP_binding PF00027.29 KDO34925.1 - 2.7e-52 174.8 2.2 1.1e-16 60.6 0.1 5.5 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KDO34925.1 - 2e-27 96.0 36.0 1.6e-11 43.9 7.1 3.9 3 0 0 3 3 3 3 Ion transport protein Ion_trans_2 PF07885.16 KDO34925.1 - 2.3e-10 40.3 21.8 4.5e-06 26.5 4.3 4.3 3 0 0 3 3 3 2 Ion channel Choline_transpo PF04515.12 KDO34926.1 - 2.9e-56 191.1 28.9 2.9e-56 191.1 28.9 2.8 3 0 0 3 3 3 1 Plasma-membrane choline transporter Hexapep PF00132.24 KDO34926.1 - 0.037 13.8 0.3 0.077 12.7 0.3 1.5 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Pkinase_Tyr PF07714.17 KDO34927.1 - 4.6e-51 173.6 0.0 7.6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO34927.1 - 5.5e-50 170.2 0.0 7.6e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KDO34927.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KDO34927.1 - 0.0048 15.7 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase GT87 PF09594.10 KDO34927.1 - 0.033 13.9 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 87 Kinase-like PF14531.6 KDO34927.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KDO34928.1 - 2e-51 174.9 0.0 2.6e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34928.1 - 2.4e-51 174.5 0.0 3.1e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO34928.1 - 0.0008 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KDO34928.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO34928.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lebercilin PF15619.6 KDO34931.1 - 0.0061 16.2 28.0 0.0062 16.2 3.5 4.2 2 1 1 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease CP12 PF02672.15 KDO34931.1 - 0.016 16.0 0.5 0.016 16.0 0.5 3.2 3 0 0 3 3 3 0 CP12 domain DUF1664 PF07889.12 KDO34931.1 - 0.035 14.1 25.4 0.04 14.0 4.4 3.7 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 KDO34931.1 - 0.47 10.8 2.4 7.4 6.9 0.0 2.9 2 1 1 3 3 3 0 Retrotransposon gag protein BLOC1_2 PF10046.9 KDO34931.1 - 0.92 9.9 14.2 4.7 7.6 2.5 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DELLA PF12041.8 KDO34931.1 - 1.3 9.0 4.7 1.1 9.2 0.3 2.7 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal T3SSipB PF16535.5 KDO34931.1 - 1.7 9.1 19.6 1.3 9.5 2.7 2.8 2 2 0 2 2 2 0 Type III cell invasion protein SipB Sec7 PF01369.20 KDO34932.1 - 1.5e-58 197.5 0.0 2.9e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KDO34932.1 - 3.5e-10 40.3 0.0 9.4e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO34932.1 - 0.093 13.2 0.0 0.6 10.6 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Mito_carr PF00153.27 KDO34933.1 - 9.6e-64 211.4 1.8 2.6e-20 72.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein STIMATE PF12400.8 KDO34934.1 - 1e-33 116.6 1.5 1.7e-33 115.8 1.5 1.4 1 0 0 1 1 1 1 STIMATE family Kelch_1 PF01344.25 KDO34935.1 - 1.5e-44 149.4 13.5 1.3e-08 34.3 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KDO34935.1 - 4.1e-41 138.0 12.7 1.5e-09 37.8 0.1 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KDO34935.1 - 2.5e-36 123.3 9.1 2e-07 31.1 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KDO34935.1 - 8.7e-35 118.5 12.2 1.9e-05 24.5 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO34935.1 - 8.3e-31 105.5 14.3 1.1e-06 28.4 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KDO34935.1 - 8.8e-31 104.7 13.0 5.5e-05 23.0 0.1 6.3 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 KDO34935.1 - 1.4e-21 76.8 1.0 5.1e-21 75.0 0.2 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KDO34935.1 - 0.00024 21.1 0.3 0.0012 18.9 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Med26 PF08711.11 KDO34940.1 - 4.2e-08 33.1 0.3 1.4e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RTP1_C1 PF10363.9 KDO34940.1 - 0.018 15.2 0.3 0.031 14.5 0.3 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 BID PF06393.11 KDO34940.1 - 0.058 12.9 0.1 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 BH3 interacting domain (BID) Mito_carr PF00153.27 KDO34941.1 - 8e-67 221.2 1.4 9.8e-26 89.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO34941.1 - 0.085 12.0 0.6 2.9 7.0 0.0 2.7 4 0 0 4 4 4 0 Gammaproteobacterial serine protease DUF4131 PF13567.6 KDO34942.1 - 0.83 9.3 3.9 1.5 8.5 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FlxA PF14282.6 KDO34945.1 - 0.0017 18.3 0.1 0.0017 18.3 0.1 3.3 2 1 1 3 3 3 1 FlxA-like protein Syntaxin_2 PF14523.6 KDO34945.1 - 0.0055 17.0 9.6 0.0063 16.9 2.2 2.5 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 KDO34945.1 - 0.01 15.6 2.7 0.01 15.6 2.7 2.8 1 1 1 2 2 2 1 Syntaxin V-SNARE PF05008.15 KDO34945.1 - 0.012 16.0 4.8 3.6 8.0 0.0 3.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DASH_Spc34 PF08657.10 KDO34945.1 - 0.016 15.0 0.8 0.023 14.5 0.8 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 MCPsignal PF00015.21 KDO34945.1 - 0.022 14.6 2.9 0.022 14.6 2.9 2.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 KDO34945.1 - 0.037 13.9 0.7 0.037 13.9 0.7 2.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF4201 PF13870.6 KDO34945.1 - 0.038 13.7 6.9 0.1 12.3 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KDO34945.1 - 0.088 12.8 12.7 4.7 7.3 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 KDO34945.1 - 0.09 12.7 10.5 0.046 13.6 3.7 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DivIVA PF05103.13 KDO34945.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.9 2 1 1 3 3 3 0 DivIVA protein Spectrin PF00435.21 KDO34945.1 - 0.32 11.5 8.1 5.5 7.5 3.2 2.5 2 1 0 2 2 2 0 Spectrin repeat RecC_C PF17946.1 KDO34945.1 - 0.4 10.4 2.5 1.6 8.5 0.4 2.3 1 1 1 2 2 2 0 RecC C-terminal domain FlaC_arch PF05377.11 KDO34945.1 - 0.48 10.8 7.5 5.4 7.5 0.3 3.6 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 KDO34945.1 - 0.55 9.7 11.5 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain COMPASS-Shg1 PF05205.12 KDO34945.1 - 1 10.1 6.1 2.2 9.0 4.0 2.3 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 IZUMO PF15005.6 KDO34945.1 - 1.1 9.8 4.2 2.4 8.6 1.0 2.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Spc7 PF08317.11 KDO34945.1 - 1.3 7.9 11.8 0.28 10.0 5.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KDO34945.1 - 2.2 8.3 5.5 27 4.8 0.2 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KDO34945.1 - 2.9 7.2 7.8 7.6 5.8 7.7 1.7 1 1 1 2 2 2 0 FAM76 protein RasGAP_C PF03836.15 KDO34945.1 - 4.1 7.5 7.1 5.5 7.1 1.6 2.7 1 1 1 2 2 2 0 RasGAP C-terminus DUF883 PF05957.13 KDO34945.1 - 7.7 7.2 8.3 5.4 7.7 0.5 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) p25-alpha PF05517.12 KDO34946.1 - 5.7e-11 42.8 0.0 8.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 p25-alpha DinB_2 PF12867.7 KDO34946.1 - 0.019 15.5 1.1 0.046 14.2 0.2 2.0 2 0 0 2 2 2 0 DinB superfamily p25-alpha PF05517.12 KDO34947.1 - 3.7e-16 59.7 0.0 4.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 p25-alpha Ephrin_rec_like PF07699.13 KDO34949.1 - 4.2e-38 128.9 110.4 3.1e-08 33.3 4.5 11.9 1 1 13 14 14 14 14 Putative ephrin-receptor like Kelch_3 PF13415.6 KDO34949.1 - 2.7e-14 53.0 12.4 0.00061 20.0 0.1 6.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KDO34949.1 - 4.1e-10 39.4 7.0 0.023 14.7 0.0 6.4 6 0 0 6 6 6 2 Kelch motif TNFR_c6 PF00020.18 KDO34949.1 - 1.4e-08 35.0 71.6 0.074 13.5 0.2 12.7 4 3 6 14 14 14 10 TNFR/NGFR cysteine-rich region Kelch_4 PF13418.6 KDO34949.1 - 3.1e-06 27.1 10.9 0.014 15.4 0.1 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain GOLD_2 PF13897.6 KDO34950.1 - 4.4e-05 24.0 0.0 0.0036 17.8 0.0 2.4 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking DUF4407 PF14362.6 KDO34950.1 - 0.00025 20.5 0.3 0.00025 20.5 0.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 KDO34950.1 - 0.0088 16.6 5.1 0.018 15.6 5.1 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Med21 PF11221.8 KDO34950.1 - 0.01 16.1 0.1 0.01 16.1 0.1 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex CENP-F_leu_zip PF10473.9 KDO34950.1 - 0.011 15.8 1.3 0.021 14.9 1.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KDO34950.1 - 0.023 15.1 0.3 0.053 13.9 0.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 KDO34950.1 - 0.025 14.7 1.0 0.025 14.7 1.0 1.8 2 0 0 2 2 1 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 KDO34950.1 - 0.028 14.7 7.1 0.089 13.0 7.1 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KDO34950.1 - 0.072 13.2 2.7 0.16 12.0 2.7 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 KDO34950.1 - 0.14 12.2 2.7 0.24 11.5 2.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A_type_inc PF04508.12 KDO34950.1 - 0.18 11.7 2.1 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ABC_tran_CTD PF16326.5 KDO34950.1 - 0.85 9.9 7.7 0.092 13.0 1.0 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Wbp11 PF09429.10 KDO34950.1 - 1 9.8 5.9 0.59 10.6 0.5 2.5 2 1 1 3 3 3 0 WW domain binding protein 11 Fez1 PF06818.15 KDO34950.1 - 1.5 9.3 5.6 0.14 12.6 0.9 1.6 2 0 0 2 2 2 0 Fez1 CLZ PF16526.5 KDO34950.1 - 3.5 8.0 6.9 0.36 11.2 1.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4404 PF14357.6 KDO34950.1 - 8.3 7.1 8.4 0.41 11.3 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) HA2 PF04408.23 KDO34951.1 - 3.3e-26 91.7 0.1 6.5e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KDO34951.1 - 2.2e-13 50.4 0.0 6.5e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KDO34951.1 - 6.1e-13 49.1 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO34951.1 - 7.4e-08 32.4 0.1 2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO34951.1 - 9.7e-05 22.7 1.9 0.0003 21.1 0.7 2.4 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KDO34951.1 - 0.00072 18.7 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KDO34951.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 KDO34951.1 - 0.024 14.1 0.1 0.065 12.7 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 KDO34951.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Helicase Microtub_bd PF16796.5 KDO34951.1 - 0.056 13.4 0.0 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding ABC_tran PF00005.27 KDO34951.1 - 0.12 12.8 0.4 3.8 8.0 0.4 2.7 1 1 0 1 1 1 0 ABC transporter Peptidase_M91 PF14891.6 KDO34951.1 - 0.21 11.9 0.1 0.4 11.0 0.1 1.4 1 0 0 1 1 1 0 Effector protein DUF815 PF05673.13 KDO34952.1 - 0.019 14.2 0.0 0.019 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PMM PF03332.13 KDO34953.1 - 1e-90 303.4 0.2 1.4e-90 303.0 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KDO34953.1 - 0.0001 22.1 0.1 0.00034 20.4 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hanta_nucleocap PF00846.18 KDO34953.1 - 0.19 10.2 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Slu7 PF11708.8 KDO34954.1 - 8.8e-93 310.9 12.4 8.8e-93 310.9 12.4 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KDO34954.1 - 0.022 14.5 0.5 0.043 13.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4050 PF13259.6 KDO34954.1 - 0.045 14.1 0.5 0.045 14.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Ribosomal_S26e PF01283.19 KDO34955.1 - 1.9e-48 163.4 7.9 2.1e-48 163.2 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e HSF_DNA-bind PF00447.17 KDO34956.1 - 2.5e-08 34.4 1.0 5e-06 27.0 1.0 2.5 1 1 0 1 1 1 1 HSF-type DNA-binding tRNA-synt_2b PF00587.25 KDO34957.1 - 1.1e-39 136.3 0.0 1.5e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KDO34957.1 - 1.3e-18 67.2 6.6 2.8e-18 66.1 6.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Oxidored_FMN PF00724.20 KDO34957.1 - 0.034 13.4 0.9 0.053 12.8 0.9 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family 2Fe-2S_thioredx PF01257.19 KDO34958.1 - 5.4e-61 204.7 0.2 6.8e-61 204.4 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin UCR_hinge PF02320.16 KDO34959.1 - 5.6e-19 68.1 1.1 6.9e-19 67.8 1.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Lipase_GDSL PF00657.22 KDO34959.1 - 0.19 11.7 0.0 0.21 11.5 0.0 1.0 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Cys_Met_Meta_PP PF01053.20 KDO34960.1 - 4.7e-37 127.4 0.0 6.1e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KDO34960.1 - 0.0018 17.6 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MutS_III PF05192.18 KDO34962.1 - 3.6 7.7 7.3 4.9 7.3 7.3 1.2 1 0 0 1 1 1 0 MutS domain III Ricin_B_lectin PF00652.22 KDO34963.1 - 6.9e-13 49.0 0.5 1.3e-12 48.1 0.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 KDO34963.1 - 3.8e-05 23.5 1.1 0.00029 20.6 0.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 RicinB_lectin_2 PF14200.6 KDO34963.1 - 0.00015 22.5 5.2 0.00034 21.3 2.4 3.0 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like SH2 PF00017.24 KDO34964.1 - 1.6e-11 44.1 0.0 4.4e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 SH2 domain TPR_12 PF13424.6 KDO34964.1 - 6e-11 42.5 9.1 4.1e-10 39.8 3.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34964.1 - 2.4e-07 30.3 6.0 0.00026 20.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO34964.1 - 3.8e-07 29.8 0.3 0.0048 17.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO34964.1 - 5e-07 29.4 6.6 3.9e-05 23.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34964.1 - 4.5e-06 26.3 2.9 0.0022 17.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KDO34964.1 - 9.5e-06 25.4 7.3 0.015 15.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KDO34964.1 - 0.044 13.9 0.2 7.1 6.8 0.0 2.4 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 KDO34964.1 - 0.051 14.4 2.3 7.9 7.6 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34964.1 - 0.086 13.5 0.9 6.7 7.6 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KDO34965.1 - 7.8e-44 150.0 0.0 1.1e-43 149.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO34965.1 - 3.7e-43 147.7 0.0 4.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO34965.1 - 0.00073 18.4 0.1 0.0015 17.4 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase MGC-24 PF05283.11 KDO34965.1 - 0.02 15.4 3.8 0.02 15.4 3.8 3.0 1 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 KDO34965.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Plasmodium_Vir PF05795.11 KDO34965.1 - 0.42 10.0 2.1 0.66 9.3 0.1 1.8 1 1 0 2 2 2 0 Plasmodium vivax Vir protein Glyco_hydro_47 PF01532.20 KDO34966.1 - 1.3e-113 380.4 0.0 1.6e-113 380.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KDO34966.1 - 7.5e-08 32.3 0.1 2.1e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 PA domain PRKCSH PF07915.13 KDO34966.1 - 6.2e-06 27.1 0.0 1.5e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KDO34966.1 - 0.0062 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Mycoplasma_p37 PF06646.11 KDO34966.1 - 0.044 13.0 0.4 0.075 12.2 0.4 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 ANAPC4_WD40 PF12894.7 KDO34967.1 - 6.4e-05 23.2 0.0 0.2 12.0 0.0 4.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO34967.1 - 9e-05 23.2 1.8 0.38 11.7 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Glyco_hydro_18 PF00704.28 KDO34968.1 - 1.2e-71 242.0 0.0 1.4e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DAGAT PF03982.13 KDO34969.1 - 0.00012 21.1 0.0 0.00018 20.5 0.0 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KDO34969.1 - 0.06 13.0 0.0 0.48 10.0 0.0 2.1 1 1 0 1 1 1 0 Acyltransferase Ank_2 PF12796.7 KDO34970.1 - 1.1e-09 38.8 0.1 8.5e-09 35.9 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KDO34970.1 - 4.4e-09 36.4 1.1 0.0022 18.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KDO34970.1 - 8.5e-07 29.1 1.3 9.6e-05 22.6 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KDO34970.1 - 1.7e-05 25.2 0.3 0.002 18.6 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO34970.1 - 2.2e-05 24.5 0.8 0.49 11.1 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeat WASH_WAHD PF11945.8 KDO34970.1 - 0.066 12.7 0.0 11 5.4 0.0 2.1 2 0 0 2 2 2 0 WAHD domain of WASH complex PIN_3 PF13470.6 KDO34970.1 - 0.073 13.8 0.4 0.14 12.9 0.4 1.5 1 0 0 1 1 1 0 PIN domain WD40 PF00400.32 KDO34971.1 - 9.2e-12 45.3 11.0 0.0014 19.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34971.1 - 3.1e-05 24.2 0.2 0.0064 16.8 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO34971.1 - 0.0011 18.8 0.0 0.0028 17.6 0.0 1.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KDO34971.1 - 0.0027 16.3 0.0 0.0051 15.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 KDO34971.1 - 0.011 15.1 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KDO34971.1 - 0.012 14.6 0.1 0.25 10.3 0.0 2.6 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Reprolysin_4 PF13583.6 KDO34971.1 - 0.048 13.3 0.2 0.19 11.4 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like HEV_ORF1 PF02444.16 KDO34971.1 - 0.21 12.2 2.1 2.1 8.9 0.3 2.3 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) APG6 PF04111.12 KDO34973.1 - 2.2e-52 177.6 0.0 2.8e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KDO34973.1 - 0.17 12.4 2.7 0.27 11.8 2.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DRIM PF07539.12 KDO34978.1 - 1.7e-113 380.1 6.1 7.4e-112 374.7 0.1 4.3 4 1 0 4 4 4 2 Down-regulated in metastasis DUF732 PF05305.14 KDO34978.1 - 0.078 13.4 0.2 0.32 11.4 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) UME PF08064.13 KDO34978.1 - 0.085 12.8 8.7 0.67 9.9 0.0 6.1 8 0 0 8 8 8 0 UME (NUC010) domain DUF3385 PF11865.8 KDO34978.1 - 0.13 12.2 15.7 1.1 9.1 0.1 7.1 8 0 0 8 8 8 0 Domain of unknown function (DUF3385) CENP-B_dimeris PF09026.10 KDO34978.1 - 0.99 9.8 7.6 7.9 6.9 2.4 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HEAT PF02985.22 KDO34978.1 - 3.5 8.1 11.8 3.9 8.0 0.5 6.3 6 0 0 6 6 6 0 HEAT repeat zf-Tim10_DDP PF02953.15 KDO34979.1 - 1.9e-17 62.6 6.1 2.5e-17 62.3 6.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 KDO34979.1 - 0.014 15.0 1.6 0.016 14.8 1.6 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Chalcone PF02431.15 KDO34979.1 - 0.15 11.5 0.7 0.18 11.2 0.7 1.0 1 0 0 1 1 1 0 Chalcone-flavanone isomerase DUF2116 PF09889.9 KDO34979.1 - 2.6 8.1 5.8 0.68 10.0 0.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Na_H_antiporter PF03553.14 KDO34980.1 - 6e-36 124.2 5.7 6e-36 124.2 5.7 2.4 1 1 1 2 2 2 1 Na+/H+ antiporter family Mito_carr PF00153.27 KDO34981.1 - 5.6e-57 189.7 7.1 1.4e-23 82.6 0.0 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KDO34981.1 - 0.0042 16.3 1.3 0.013 14.6 0.0 2.4 4 0 0 4 4 4 1 Gammaproteobacterial serine protease ZapC PF07126.12 KDO34981.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Cell-division protein ZapC AdHead_fibreRBD PF16812.5 KDO34982.1 - 0.069 13.0 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Kri1 PF05178.12 KDO34982.1 - 0.31 11.6 0.0 0.31 11.6 0.0 2.7 3 0 0 3 3 3 0 KRI1-like family FliJ PF02050.16 KDO34982.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.2 4 0 0 4 4 4 0 Flagellar FliJ protein WD40 PF00400.32 KDO34982.1 - 2.7 9.0 0.0 2.7 9.0 0.0 6.3 6 2 1 7 7 7 0 WD domain, G-beta repeat NopRA1 PF16201.5 KDO34983.1 - 1.7e-52 178.0 0.5 1.7e-52 178.0 0.5 2.4 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 KDO34983.1 - 1.6e-24 86.9 0.5 3.6e-24 85.7 0.5 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Nefa_Nip30_N PF10187.9 KDO34984.1 - 6.5e-16 58.6 0.2 6.5e-16 58.6 0.2 1.4 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 AJAP1_PANP_C PF15298.6 KDO34984.1 - 0.33 11.1 2.5 0.48 10.6 2.5 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus eIF3_N PF09440.10 KDO34985.1 - 2.6e-39 134.7 2.1 2.6e-39 134.7 2.1 2.2 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KDO34985.1 - 2.1e-12 47.5 0.2 5.2e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 PCI domain TPR_3 PF07720.12 KDO34985.1 - 0.0039 17.1 3.4 0.0094 15.9 3.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO34985.1 - 0.045 14.0 1.0 0.18 12.1 0.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MutS_V PF00488.21 KDO34986.1 - 6.5e-74 248.0 1.5 7.8e-74 247.8 0.2 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KDO34986.1 - 1.3e-25 90.8 0.1 2.5e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KDO34986.1 - 3e-11 43.5 0.0 5.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KDO34986.1 - 0.00011 22.5 0.3 0.0022 18.3 0.1 2.6 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 KDO34986.1 - 0.037 13.6 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KDO34986.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KDO34988.1 - 4.1e-35 121.1 0.0 1e-34 119.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO34988.1 - 5.8e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KDO34988.1 - 6.2e-05 23.4 0.1 0.0037 17.7 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO34988.1 - 0.00044 20.5 0.1 0.066 13.5 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KDO34988.1 - 0.00073 19.5 0.0 0.03 14.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO34988.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KDO34988.1 - 0.0043 16.3 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KDO34988.1 - 0.0051 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KDO34988.1 - 0.0069 15.5 0.0 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KDO34988.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KDO34988.1 - 0.0088 15.3 0.2 0.018 14.3 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KDO34988.1 - 0.015 15.9 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KDO34988.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KDO34988.1 - 0.02 14.3 0.2 0.11 11.8 0.1 2.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KDO34988.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KDO34988.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KDO34988.1 - 0.028 14.8 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 KDO34988.1 - 0.029 14.4 0.0 0.082 12.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.18 KDO34988.1 - 0.038 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_2 PF07724.14 KDO34988.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KDO34988.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KDO34988.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.12 KDO34988.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KDO34988.1 - 0.21 10.9 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 KDO34988.1 - 0.21 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PLU-1 PF08429.11 KDO34989.1 - 1.4e-37 129.7 11.5 8.7e-18 64.6 0.6 6.1 3 2 3 6 6 6 6 PLU-1-like protein PHD PF00628.29 KDO34989.1 - 5.6e-10 38.9 6.0 1.2e-09 37.9 6.0 1.6 1 0 0 1 1 1 1 PHD-finger ELM2 PF01448.24 KDO34989.1 - 0.041 14.6 0.5 0.26 12.1 0.0 2.8 3 0 0 3 3 3 0 ELM2 domain MutS_III PF05192.18 KDO34989.1 - 0.066 13.4 3.3 3.8 7.7 0.4 3.7 2 1 0 2 2 2 0 MutS domain III BING4CT PF08149.11 KDO34990.1 - 5.1e-38 128.7 0.0 2.7e-36 123.2 0.0 2.9 3 0 0 3 3 3 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KDO34990.1 - 3.9e-05 23.9 0.0 0.19 12.0 0.0 3.6 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO34990.1 - 0.00014 22.6 0.1 0.0032 18.3 0.0 3.2 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40_like PF17005.5 KDO34990.1 - 0.02 14.2 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain DUF5302 PF17227.2 KDO34990.1 - 0.048 14.7 1.7 0.048 14.7 1.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5302) R3H PF01424.22 KDO34991.1 - 9.6e-13 47.9 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 KDO34991.1 - 1.6e-10 41.6 1.6 1.6e-10 41.6 1.6 2.5 3 0 0 3 3 3 1 SUZ domain Ada3 PF10198.9 KDO34992.1 - 2e-06 27.9 18.9 7.4e-05 22.9 18.9 2.0 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 Coilin_N PF15862.5 KDO34992.1 - 0.03 14.1 5.9 0.046 13.5 5.9 1.3 1 0 0 1 1 1 0 Coilin N-terminus Med19 PF10278.9 KDO34992.1 - 0.1 12.5 5.7 0.13 12.2 5.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TPR_2 PF07719.17 KDO34993.1 - 7.6e-08 31.9 0.3 0.00033 20.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO34993.1 - 5e-06 26.1 0.0 0.035 13.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KDO34993.1 - 9.6e-06 26.0 4.7 0.018 15.8 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO34993.1 - 2.4e-05 24.0 0.2 0.12 12.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KDO34993.1 - 4.1e-05 24.0 0.1 0.087 13.5 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO34993.1 - 4.8e-05 23.9 5.2 0.013 16.2 0.0 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO34993.1 - 4.9e-05 22.9 0.2 0.99 9.1 0.1 3.3 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 KDO34993.1 - 0.00013 21.9 0.0 0.12 12.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO34993.1 - 0.00026 21.4 0.2 0.7 10.5 0.0 3.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO34993.1 - 0.00031 20.9 1.6 1.3 9.6 0.0 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KDO34993.1 - 0.00046 20.4 0.5 0.75 10.1 0.1 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KDO34993.1 - 0.00072 19.8 8.0 0.23 11.8 0.6 3.0 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KDO34993.1 - 0.0026 18.1 0.8 2.9 8.3 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 KDO34993.1 - 0.025 15.2 11.3 0.047 14.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FAT PF02259.23 KDO34993.1 - 0.046 12.9 0.0 0.79 8.9 0.0 2.0 1 1 1 2 2 2 0 FAT domain TPR_10 PF13374.6 KDO34993.1 - 0.06 13.2 2.8 3.8 7.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 KDO34994.1 - 2.6e-23 81.8 12.7 6e-09 36.4 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO34994.1 - 1.1e-13 51.3 0.1 1.2e-05 25.5 0.3 4.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO34994.1 - 0.0005 20.0 0.3 1.2 9.0 0.0 4.5 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KDO34994.1 - 0.073 13.0 1.9 11 6.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat p53-inducible11 PF14936.6 KDO34995.1 - 0.00019 21.5 1.2 0.00022 21.3 1.2 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 EMP24_GP25L PF01105.24 KDO34996.1 - 7e-31 107.6 0.0 8e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FCD PF07729.12 KDO34996.1 - 0.016 15.7 0.6 0.024 15.0 0.1 1.5 2 0 0 2 2 2 0 FCD domain Mn_catalase PF05067.12 KDO34996.1 - 0.058 12.4 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Manganese containing catalase PCAF_N PF06466.11 KDO34999.1 - 0.0068 16.0 0.6 1 8.9 0.5 2.5 1 1 1 2 2 2 2 PCAF (P300/CBP-associated factor) N-terminal domain Radial_spoke_3 PF06098.11 KDO35000.1 - 1.1e-99 333.3 6.9 1.3e-99 333.1 6.9 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 AAA_32 PF13654.6 KDO35000.1 - 0.00074 18.4 3.6 0.00093 18.1 3.6 1.2 1 0 0 1 1 1 1 AAA domain MIP PF00230.20 KDO35001.1 - 1.6e-52 178.5 7.1 1.9e-52 178.2 7.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1418 PF07214.12 KDO35001.1 - 0.087 12.7 0.3 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) SET PF00856.28 KDO35002.1 - 4.3e-07 30.5 0.0 8.4e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 SET domain Lactamase_B_2 PF12706.7 KDO35003.1 - 3.9e-07 29.8 0.1 0.016 14.8 0.0 2.7 3 1 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO35003.1 - 0.00081 19.5 0.7 0.0021 18.1 0.7 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-HC5HC2H PF13771.6 KDO35004.1 - 0.0081 16.4 6.0 0.0081 16.4 6.0 2.9 2 1 0 2 2 2 1 PHD-like zinc-binding domain C1_1 PF00130.22 KDO35004.1 - 0.0088 15.9 4.5 0.0088 15.9 4.5 2.9 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KDO35004.1 - 0.015 15.2 7.8 0.015 15.2 7.8 2.5 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KDO35004.1 - 0.017 15.3 4.5 0.017 15.3 4.5 2.8 3 1 0 3 3 3 0 PHD-zinc-finger like domain DUF383 PF04063.14 KDO35004.1 - 0.052 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Rhodanese_C PF12368.8 KDO35004.1 - 0.076 13.4 5.2 0.39 11.1 5.2 2.3 1 0 0 1 1 1 0 Rhodanase C-terminal HTH_Tnp_Tc5 PF03221.16 KDO35006.1 - 1.8e-13 50.3 0.4 2.1e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KDO35006.1 - 6.3e-07 29.2 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4143 PF13635.6 KDO35006.1 - 0.065 13.4 0.0 0.9 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4143) Exo_endo_phos PF03372.23 KDO35007.1 - 2.8e-07 30.3 0.2 3.8e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RanBP PF00641.18 KDO35007.1 - 0.0015 17.8 3.5 0.0028 16.9 3.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RabGAP-TBC PF00566.18 KDO35009.1 - 7.1e-41 140.2 0.0 9.5e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CH PF00307.31 KDO35009.1 - 5.7e-14 52.2 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CN_hydrolase PF00795.22 KDO35011.1 - 2.7e-50 171.1 0.1 5.5e-50 170.1 0.1 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase UPF0242 PF06785.11 KDO35011.1 - 0.041 14.0 0.2 0.041 14.0 0.2 4.0 2 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 KDO35011.1 - 0.14 12.0 0.1 5.9 6.8 0.0 3.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec7 PF01369.20 KDO35012.1 - 9.3e-56 188.4 0.0 1.8e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KDO35012.1 - 9.4e-13 48.4 0.3 3.7e-12 46.4 0.3 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PH PF00169.29 KDO35012.1 - 9.4e-06 26.1 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 PH domain bZIP_1 PF00170.21 KDO35013.1 - 8.3e-13 48.2 8.8 8.3e-13 48.2 8.8 2.4 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KDO35013.1 - 3e-09 36.8 8.9 3e-09 36.8 8.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DUF1548 PF07579.11 KDO35013.1 - 0.1 13.0 0.4 0.47 10.8 0.0 2.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) bZIP_Maf PF03131.17 KDO35013.1 - 3.1 8.4 17.3 0.054 14.0 7.3 2.7 2 1 0 2 2 2 0 bZIP Maf transcription factor Cullin PF00888.22 KDO35014.1 - 1.2e-176 589.0 2.2 1.5e-176 588.7 2.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KDO35014.1 - 2.9e-25 88.1 2.0 4.4e-25 87.5 0.7 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain WD40 PF00400.32 KDO35015.1 - 6.3e-11 42.7 0.1 0.063 14.2 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35015.1 - 4.1e-07 30.2 0.0 3.3 8.1 0.0 5.2 1 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KDO35015.1 - 0.00026 19.6 0.0 0.00048 18.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Sorting_nexin PF03700.13 KDO35015.1 - 1.2 9.7 3.9 2.7 8.6 3.7 1.7 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain LRR_4 PF12799.7 KDO35016.1 - 3.5e-21 74.9 12.1 3e-05 24.3 0.0 5.5 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO35016.1 - 5.4e-17 61.3 17.7 2.8e-08 33.4 1.0 4.9 2 1 3 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 KDO35016.1 - 2.2e-08 33.5 12.4 1.3 9.3 0.1 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 KDO35016.1 - 2.2e-05 24.0 1.7 0.063 12.8 0.2 2.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KDO35016.1 - 9.8e-05 22.4 16.2 5.9 7.8 0.6 6.7 6 1 0 6 6 6 2 Leucine Rich Repeat ECH_1 PF00378.20 KDO35017.1 - 4.1e-66 222.9 0.2 4.6e-66 222.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO35017.1 - 6.9e-31 108.0 0.5 8.2e-30 104.4 0.6 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Elicitin PF00964.17 KDO35018.1 - 0.00087 19.3 4.0 0.096 12.8 0.7 2.8 2 2 0 2 2 2 2 Elicitin RPAP2_Rtr1 PF04181.13 KDO35018.1 - 0.059 13.7 0.9 1.2 9.6 0.0 3.1 4 0 0 4 4 4 0 Rtr1/RPAP2 family CoA_transf_3 PF02515.17 KDO35019.1 - 7.7e-101 337.8 0.0 8.8e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III His_Phos_2 PF00328.22 KDO35020.1 - 1.2e-31 110.5 0.0 1.5e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5375 PF17345.2 KDO35020.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5375) ERG4_ERG24 PF01222.17 KDO35021.1 - 3e-76 256.9 12.8 3.4e-76 256.7 12.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KDO35021.1 - 0.0017 17.9 0.2 0.0043 16.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) 3Beta_HSD PF01073.19 KDO35022.1 - 0.0064 15.5 0.7 0.0085 15.1 0.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_17 PF13207.6 KDO35022.1 - 0.02 15.3 1.1 0.034 14.6 1.1 1.4 1 0 0 1 1 1 0 AAA domain FYVE_2 PF02318.16 KDO35022.1 - 0.036 14.3 5.2 0.055 13.7 4.6 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger DUF4333 PF14230.6 KDO35022.1 - 0.074 13.3 0.9 0.25 11.6 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4333) CHCH PF06747.13 KDO35022.1 - 0.17 12.1 3.8 0.29 11.3 3.8 1.4 1 0 0 1 1 1 0 CHCH domain Peptidase_C1 PF00112.23 KDO35023.1 - 1.6e-96 322.6 16.8 5e-53 180.4 1.0 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KDO35023.1 - 0.11 11.2 10.0 0.56 8.9 0.8 2.9 3 0 0 3 3 3 0 Peptidase C1-like family Cellulase PF00150.18 KDO35024.1 - 5.2e-28 98.3 0.0 8.5e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KDO35025.1 - 1.1e-29 103.8 0.0 1.5e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KDO35026.1 - 4.3e-30 105.1 0.2 5.6e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAM72 PF14976.6 KDO35026.1 - 0.083 13.0 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 FAM72 protein Cellulase PF00150.18 KDO35027.1 - 4.6e-27 95.2 0.0 6.3e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 KDO35029.1 - 5.8e-23 81.6 0.0 7.6e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35029.1 - 3.5e-17 62.6 0.0 4.8e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO35029.1 - 0.045 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NAD_binding_6 PF08030.12 KDO35030.1 - 4.2e-32 111.4 0.0 7.9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KDO35030.1 - 1.2e-20 73.7 0.0 2.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KDO35030.1 - 1.6e-14 54.1 5.8 1.6e-14 54.1 5.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KDO35030.1 - 0.01 16.5 0.0 0.034 14.8 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain EF-hand_6 PF13405.6 KDO35030.1 - 0.046 13.7 0.2 0.34 11.0 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 KDO35030.1 - 0.071 13.6 0.1 0.81 10.2 0.1 2.4 2 1 1 3 3 3 0 EF-hand domain pair Ald_Xan_dh_C2 PF02738.18 KDO35031.1 - 1.3e-194 647.8 10.5 1.8e-194 647.3 10.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KDO35031.1 - 4e-40 137.3 0.0 8.7e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 KDO35031.1 - 1.7e-28 98.5 0.4 4.7e-28 97.0 0.4 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KDO35031.1 - 6.6e-27 93.7 0.0 1.9e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KDO35031.1 - 2.4e-26 92.3 0.6 8.5e-26 90.5 0.6 2.1 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 KDO35031.1 - 9.5e-08 31.9 1.1 9.5e-08 31.9 1.1 2.7 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DREV PF05219.12 KDO35032.1 - 1.1e-59 201.7 0.0 1.3e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KDO35032.1 - 3.8e-11 43.1 0.0 6.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO35032.1 - 2.6e-07 31.3 0.0 4.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KDO35032.1 - 1.7e-05 25.4 0.0 4.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO35032.1 - 0.00089 19.9 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KDO35032.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.17 KDO35032.1 - 0.1 11.7 0.0 1.5 7.9 0.0 2.0 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 KDO35032.1 - 0.2 11.5 0.1 22 4.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Kinesin PF00225.23 KDO35033.1 - 7.5e-58 196.0 0.1 1e-57 195.6 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO35033.1 - 6.5e-12 45.6 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KDO35033.1 - 0.017 15.5 0.0 0.05 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 KDO35033.1 - 0.023 14.5 1.5 0.024 14.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO35033.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KDO35033.1 - 0.039 13.5 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KDO35033.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KDO35033.1 - 0.14 12.5 0.0 0.58 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DnaJ PF00226.31 KDO35034.1 - 4.8e-25 87.5 0.7 4.8e-25 87.5 0.7 2.8 3 0 0 3 3 3 1 DnaJ domain TF_AP-2 PF03299.14 KDO35034.1 - 0.045 13.7 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 Transcription factor AP-2 Nuc_sug_transp PF04142.15 KDO35035.1 - 1.6e-46 158.9 21.3 3.5e-46 157.8 21.3 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KDO35035.1 - 0.00098 18.4 17.4 0.0051 16.0 17.0 2.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KDO35035.1 - 0.063 13.5 36.2 0.029 14.6 10.4 2.7 2 1 0 2 2 2 0 EamA-like transporter family TMEM43 PF07787.12 KDO35035.1 - 7 6.0 6.7 17 4.7 6.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 43 LMBR1 PF04791.16 KDO35036.1 - 1.6e-11 43.8 21.5 2.1e-09 36.9 7.0 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein His_Phos_2 PF00328.22 KDO35037.1 - 3.6e-15 56.2 0.0 3.6e-07 29.9 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF389 PF04087.14 KDO35037.1 - 0.0085 16.1 0.2 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF389) Las1 PF04031.13 KDO35038.1 - 2.7e-42 144.5 1.1 4.3e-42 143.8 1.1 1.3 1 0 0 1 1 1 1 Las1-like Methyltransf_16 PF10294.9 KDO35040.1 - 5.7e-11 42.5 0.1 3.5e-10 39.9 0.1 1.9 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO35040.1 - 0.00059 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KDO35040.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KDO35040.1 - 0.0034 18.1 0.0 0.0089 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KDO35040.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Toprim PF01751.22 KDO35040.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Toprim domain TIM21 PF08294.11 KDO35041.1 - 5.3 6.9 5.7 3.8 7.4 3.8 1.8 1 1 1 2 2 2 0 TIM21 GCV_H PF01597.19 KDO35042.1 - 4.4e-35 120.2 0.1 5.3e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KDO35042.1 - 0.0008 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KDO35042.1 - 0.0025 17.6 0.1 0.0039 17.0 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Hint PF01079.20 KDO35042.1 - 0.036 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Hint module Ribonuclease_T2 PF00445.18 KDO35043.1 - 8.9e-26 91.2 0.0 1.2e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family PX PF00787.24 KDO35044.1 - 1.3e-09 38.1 0.1 2.4e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 PX domain MMtag PF10159.9 KDO35045.1 - 5.1e-31 106.8 1.6 5.1e-31 106.8 1.6 2.4 2 0 0 2 2 2 1 Multiple myeloma tumor-associated GAGA_bind PF06217.12 KDO35045.1 - 0.03 14.6 7.6 0.033 14.5 7.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PRP38_assoc PF12871.7 KDO35045.1 - 0.077 13.6 27.0 0.045 14.4 24.6 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Thg1C PF14413.6 KDO35045.1 - 0.4 10.9 6.1 0.94 9.6 6.1 1.7 1 0 0 1 1 1 0 Thg1 C terminal domain CDC45 PF02724.14 KDO35045.1 - 3.7 5.7 15.6 4.7 5.4 15.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1509 PF07420.11 KDO35045.1 - 4.7 6.1 9.8 6.1 5.7 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) RNA_pol_Rpc4 PF05132.14 KDO35045.1 - 7.4 7.0 10.1 13 6.2 10.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_S49_N PF08496.10 KDO35045.1 - 9.7 6.2 12.2 22 5.1 12.2 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MatE PF01554.18 KDO35046.1 - 2.7e-46 157.2 39.3 4.1e-23 81.8 13.2 2.4 2 0 0 2 2 2 2 MatE MatE PF01554.18 KDO35047.1 - 5.2e-45 153.0 37.0 2.1e-25 89.2 8.8 2.5 3 0 0 3 3 3 2 MatE LigB PF02900.18 KDO35047.1 - 0.1 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_C31 PF05410.13 KDO35047.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha 7tm_3 PF00003.22 KDO35048.1 - 6e-37 127.6 25.6 1e-36 126.9 25.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR VPS13_C PF16909.5 KDO35051.1 - 1.6e-49 168.1 0.2 9.4e-46 155.8 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KDO35051.1 - 1.8e-23 83.3 0.0 4.1e-16 59.2 0.0 4.8 4 1 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KDO35051.1 - 7.5e-13 48.8 0.1 3.1e-10 40.2 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal PH PF00169.29 KDO35051.1 - 1e-12 48.5 0.0 0.0016 18.9 0.0 3.7 3 0 0 3 3 3 3 PH domain Chorein_N PF12624.7 KDO35051.1 - 1.2e-12 47.9 0.1 5.7e-12 45.8 0.0 2.3 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KDO35051.1 - 0.00013 22.2 0.1 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain PDZ_6 PF17820.1 KDO35051.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KDO35051.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Apt1 PF10351.9 KDO35051.1 - 0.19 10.6 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMC_N PF02463.19 KDO35052.1 - 7.2e-26 91.0 0.3 1.1e-25 90.4 0.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO35052.1 - 1.9e-10 41.6 34.9 1.9e-10 41.6 34.9 5.1 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KDO35052.1 - 1.2e-05 25.3 1.9 1.2e-05 25.3 1.9 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KDO35052.1 - 0.012 15.3 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KDO35052.1 - 0.016 15.0 1.2 0.073 12.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DASH_Dad3 PF08656.10 KDO35052.1 - 4.5 7.4 7.9 2.4 8.3 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad3 Nbl1_Borealin_N PF10444.9 KDO35053.1 - 2.5e-09 36.6 3.7 2.5e-09 36.6 3.7 2.8 4 0 0 4 4 4 1 Nbl1 / Borealin N terminal Apolipoprotein PF01442.18 KDO35053.1 - 0.0088 15.9 1.1 0.23 11.3 0.1 2.1 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain Borealin PF10512.9 KDO35053.1 - 3.6 7.6 9.9 0.83 9.6 4.9 2.6 2 1 0 2 2 2 0 Cell division cycle-associated protein 8 2OG-FeII_Oxy_2 PF13532.6 KDO35054.1 - 4.7e-36 124.8 0.0 6.5e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ctr PF04145.15 KDO35055.1 - 0.032 14.8 0.0 0.034 14.8 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF3989 PF13150.6 KDO35055.1 - 0.04 13.6 0.3 0.08 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF3099 PF11298.8 KDO35055.1 - 0.054 13.6 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DUF334 PF03904.13 KDO35055.1 - 0.23 11.0 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DNA_pol_B PF00136.21 KDO35056.1 - 1.5e-89 300.9 0.0 2.1e-89 300.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KDO35056.1 - 7e-17 61.6 0.0 8.5e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KDO35056.1 - 6.9e-08 32.9 1.1 1.8e-07 31.5 1.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta OrfB_Zn_ribbon PF07282.11 KDO35056.1 - 0.00024 20.9 0.1 0.0059 16.5 0.0 2.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Pentapeptide_2 PF01469.18 KDO35057.1 - 0.91 9.5 5.2 1.9 8.5 5.2 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Helicase_C PF00271.31 KDO35058.1 - 2.4e-06 27.9 0.0 4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1877 PF08974.10 KDO35060.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Zwilch PF09817.9 KDO35060.1 - 0.033 12.6 0.0 0.05 12.0 0.0 1.2 1 0 0 1 1 1 0 RZZ complex, subunit zwilch Radical_SAM_C PF16199.5 KDO35061.1 - 2.3e-22 78.8 0.2 4.3e-22 77.9 0.2 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KDO35061.1 - 3.4e-15 56.8 0.5 1.2e-14 55.0 0.3 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KDO35061.1 - 6.7e-08 32.8 0.1 2.3e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO35061.1 - 2.7e-05 24.1 0.1 5.8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO35061.1 - 0.0075 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ParA PF10609.9 KDO35062.1 - 8.3e-78 261.2 0.1 1.1e-77 260.8 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 KDO35062.1 - 3.8e-16 59.5 0.0 8.9e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CbiA PF01656.23 KDO35062.1 - 2.6e-13 50.1 0.0 4.3e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KDO35062.1 - 1e-10 41.8 0.4 1.9e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KDO35062.1 - 5.5e-09 35.7 0.2 2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 ATPase MipZ FeS_assembly_P PF01883.19 KDO35062.1 - 3.6e-08 33.5 0.0 9.3e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ArsA_ATPase PF02374.15 KDO35062.1 - 1.2e-06 27.9 0.1 0.04 13.1 0.2 2.4 2 0 0 2 2 2 2 Anion-transporting ATPase CBP_BcsQ PF06564.12 KDO35062.1 - 0.00029 20.4 0.3 0.0026 17.3 0.3 2.2 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 KDO35062.1 - 0.00059 19.2 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 KDO35062.1 - 0.0044 16.5 0.2 0.0067 15.9 0.2 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 KDO35062.1 - 0.043 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KDO35062.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase IL17 PF06083.11 KDO35062.1 - 0.15 12.6 0.0 0.51 10.9 0.0 1.9 2 0 0 2 2 2 0 Interleukin-17 FTHFS PF01268.19 KDO35062.1 - 0.17 10.0 0.0 0.27 9.4 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase MOZ_SAS PF01853.18 KDO35063.1 - 7.9e-64 214.6 0.0 1.4e-63 213.8 0.0 1.4 1 1 1 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KDO35063.1 - 8.9e-17 60.4 1.7 1.2e-16 60.0 0.2 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KDO35063.1 - 0.00025 21.4 0.0 0.00046 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO35063.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PhnA_Zn_Ribbon PF08274.12 KDO35063.1 - 0.082 12.9 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF4423 PF14394.6 KDO35063.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Acetyltransf_10 PF13673.7 KDO35063.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.31 KDO35064.1 - 3e-09 36.9 0.2 7.3e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain SnAPC_2_like PF11035.8 KDO35064.1 - 0.045 13.9 0.1 0.056 13.6 0.1 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF3887 PF13026.6 KDO35064.1 - 0.18 12.6 1.2 11 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Pur_ac_phosph_N PF16656.5 KDO35065.1 - 5.2e-23 81.4 0.8 1.3e-22 80.2 0.2 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KDO35065.1 - 2.3e-20 74.0 0.0 4.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KDO35065.1 - 1e-16 61.5 0.1 4.3e-16 59.5 0.2 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 KDO35065.1 - 0.043 14.0 0.1 0.4 10.9 0.0 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SWIB PF02201.18 KDO35066.1 - 2.8e-60 200.2 1.3 2.7e-29 100.8 0.0 3.1 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.11 KDO35066.1 - 6.3e-16 58.0 2.6 2.3e-15 56.3 2.6 2.0 1 0 0 1 1 1 1 DEK C terminal domain TSP9 PF11493.8 KDO35066.1 - 0.052 14.2 0.2 0.052 14.2 0.2 2.8 3 1 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 DUF3246 PF11596.8 KDO35066.1 - 1 8.7 5.3 0.17 11.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF4611 PF15387.6 KDO35066.1 - 1.3 9.3 16.1 0.098 12.9 2.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KDO35066.1 - 3.4 5.9 8.9 6.4 4.9 3.5 2.2 2 0 0 2 2 2 0 CDC45-like protein FHA PF00498.26 KDO35067.1 - 3.2e-16 59.4 0.0 6.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain WD40 PF00400.32 KDO35067.1 - 1.7e-13 50.8 11.0 0.00011 22.9 0.1 5.9 5 1 1 6 6 6 2 WD domain, G-beta repeat Yop-YscD_cpl PF16697.5 KDO35067.1 - 1.7e-07 31.4 0.1 6.5e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain TFB6 PF17110.5 KDO35067.1 - 0.15 11.8 1.0 0.31 10.8 1.0 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 KDO35067.1 - 3 5.8 11.5 4.2 5.3 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KDO35067.1 - 5.6 6.6 13.1 12 5.5 13.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Adaptin_binding PF10199.9 KDO35068.1 - 0.1 13.2 6.6 15 6.2 9.4 2.8 2 2 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 HA2 PF04408.23 KDO35068.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.8 3 1 0 3 3 3 0 Helicase associated domain (HA2) GREB1 PF15782.5 KDO35068.1 - 6.2 3.8 10.8 8.4 3.4 10.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MatE PF01554.18 KDO35069.1 - 5.7e-38 130.1 24.6 7.3e-22 77.7 10.3 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KDO35069.1 - 7.5e-05 22.8 28.9 0.00019 21.5 7.0 3.7 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KDO35070.1 - 2.5e-20 72.7 22.6 6.1e-11 42.2 12.0 2.7 3 0 0 3 3 3 2 MatE MatE PF01554.18 KDO35071.1 - 1.3e-50 171.2 28.7 1.5e-27 96.2 8.4 2.2 2 0 0 2 2 2 2 MatE SlyX PF04102.12 KDO35072.1 - 0.0021 18.6 0.6 0.017 15.7 0.5 2.6 2 0 0 2 2 2 1 SlyX ZapB PF06005.12 KDO35072.1 - 0.2 12.1 1.7 0.57 10.7 1.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapB AAA_23 PF13476.6 KDO35073.1 - 8.3e-31 108.1 0.0 8.3e-31 108.1 0.0 6.0 3 1 0 4 4 4 1 AAA domain SMC_N PF02463.19 KDO35073.1 - 3.7e-16 59.2 0.0 4.7e-15 55.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KDO35073.1 - 3.6e-13 50.0 0.3 7.8e-07 29.1 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KDO35073.1 - 1.3e-09 38.3 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 KDO35073.1 - 1e-05 25.3 1.7 4.9e-05 23.1 0.2 3.2 2 0 0 2 2 2 1 Rad50 zinc hook motif SbcCD_C PF13558.6 KDO35073.1 - 0.0002 21.5 0.0 0.00074 19.7 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KDO35073.1 - 0.011 16.3 18.1 0.024 15.1 0.0 5.5 4 2 0 4 4 4 0 ABC transporter AAA_29 PF13555.6 KDO35073.1 - 0.076 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KDO35073.1 - 0.33 11.2 0.0 0.33 11.2 0.0 5.9 7 1 1 8 8 8 0 AAA domain BAG PF02179.16 KDO35074.1 - 2.5e-08 34.2 0.4 5.2e-08 33.2 0.4 1.6 1 0 0 1 1 1 1 BAG domain RRN3 PF05327.11 KDO35074.1 - 0.0078 14.8 3.5 0.0085 14.7 3.5 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KDO35074.1 - 0.018 14.5 9.4 0.023 14.1 9.4 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KDO35074.1 - 0.072 11.9 1.6 0.085 11.6 1.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KDO35074.1 - 0.12 11.7 6.8 0.15 11.4 6.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KDO35074.1 - 0.17 10.1 13.6 0.23 9.7 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family FRQ PF09421.10 KDO35074.1 - 0.19 9.7 3.9 0.21 9.6 3.9 1.0 1 0 0 1 1 1 0 Frequency clock protein CobT PF06213.12 KDO35074.1 - 0.3 10.5 12.2 0.45 9.9 12.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 KDO35074.1 - 0.45 9.9 10.2 0.66 9.3 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 KDO35074.1 - 0.47 8.5 18.9 0.63 8.1 18.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 KDO35074.1 - 0.69 9.8 10.5 1.3 8.9 10.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 KDO35074.1 - 1.2 7.1 3.5 1.4 6.9 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tim54 PF11711.8 KDO35074.1 - 1.3 7.7 4.1 1.8 7.3 4.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YL1 PF05764.13 KDO35074.1 - 2.2 8.3 12.7 2.9 8.0 12.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.11 KDO35074.1 - 2.2 7.8 14.8 3 7.4 14.8 1.1 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.16 KDO35074.1 - 3 7.0 10.4 4.2 6.5 10.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GCIP PF13324.6 KDO35074.1 - 4.9 6.7 7.3 9.6 5.7 7.3 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Red1 PF07964.11 KDO35074.1 - 8.5 4.5 6.1 12 4.0 6.1 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Abhydrolase_1 PF00561.20 KDO35075.1 - 1.7e-15 57.4 0.0 2.3e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO35075.1 - 2.6e-11 43.3 0.1 1.2e-10 41.1 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO35075.1 - 1.4e-06 29.1 0.5 1.4e-06 29.1 0.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family MOZART1 PF12554.8 KDO35076.1 - 1.3e-22 79.3 0.0 1.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.7 KDO35076.1 - 0.011 15.4 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated AAA_2 PF07724.14 KDO35077.1 - 4.7e-44 150.5 1.6 6.8e-36 123.9 0.7 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KDO35077.1 - 3e-17 63.3 0.6 1.6e-07 31.8 0.1 2.8 2 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KDO35077.1 - 1.1e-08 35.0 2.2 3.8e-08 33.3 0.2 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KDO35077.1 - 1.9e-08 34.4 0.3 1.6e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KDO35077.1 - 1.7e-06 27.9 1.3 0.00018 21.3 0.1 3.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 KDO35077.1 - 2.5e-06 26.8 0.1 0.00055 19.1 0.0 2.6 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 KDO35077.1 - 3.8e-06 27.4 1.7 2.8e-05 24.6 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO35077.1 - 7.4e-06 26.3 0.1 8.8e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KDO35077.1 - 2.6e-05 23.7 0.3 0.0017 17.8 0.0 3.2 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 KDO35077.1 - 3.1e-05 23.7 1.0 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 KDO35077.1 - 0.00022 20.5 0.1 0.00026 20.3 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_33 PF13671.6 KDO35077.1 - 0.00024 21.3 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KDO35077.1 - 0.00061 19.5 0.3 0.046 13.4 0.0 3.2 3 2 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 KDO35077.1 - 0.00072 18.9 0.1 0.0023 17.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KDO35077.1 - 0.0016 19.0 0.4 0.011 16.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KDO35077.1 - 0.0045 17.5 0.1 0.013 16.0 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 KDO35077.1 - 0.0051 16.8 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KDO35077.1 - 0.0055 17.0 0.1 0.033 14.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 KDO35077.1 - 0.012 15.3 0.0 0.057 13.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KDO35077.1 - 0.016 14.6 0.0 0.048 13.1 0.0 1.9 1 1 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 KDO35077.1 - 0.017 14.9 0.4 0.088 12.5 0.4 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO35077.1 - 0.025 14.9 0.0 0.45 10.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 KDO35077.1 - 0.032 14.1 0.0 0.87 9.5 0.0 2.5 1 1 1 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KDO35077.1 - 0.034 13.7 0.0 0.094 12.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KDO35077.1 - 0.035 14.0 3.0 2.3 8.1 2.7 2.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KDO35077.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 KDO35077.1 - 0.045 13.4 2.5 0.25 11.0 0.0 3.0 3 1 1 4 4 4 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KDO35077.1 - 0.047 13.7 0.0 0.26 11.3 0.0 2.2 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KDO35077.1 - 0.052 13.5 1.4 0.82 9.6 0.1 2.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 KDO35077.1 - 0.067 13.1 0.1 0.67 9.9 0.0 2.5 3 1 0 3 3 2 0 NACHT domain AAA_19 PF13245.6 KDO35077.1 - 0.17 12.2 3.7 0.96 9.8 3.7 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KDO35077.1 - 0.68 10.4 5.6 9.1 6.7 0.1 3.8 3 1 1 4 4 3 0 AAA domain CBS PF00571.28 KDO35079.1 - 0.00052 20.4 0.0 1.6 9.2 0.0 3.1 2 0 0 2 2 2 2 CBS domain Peptidase_M50B PF13398.6 KDO35080.1 - 5.4e-17 62.1 18.5 5.4e-17 62.1 18.5 1.5 1 1 1 2 2 2 1 Peptidase M50B-like GDP_Man_Dehyd PF16363.5 KDO35081.1 - 1.9e-73 247.8 0.0 3.2e-73 247.0 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KDO35081.1 - 2.4e-60 204.0 0.0 2.8e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KDO35081.1 - 7.6e-18 64.6 0.2 9.4e-16 57.8 0.1 3.0 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KDO35081.1 - 8.4e-17 61.1 0.0 6.5e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KDO35081.1 - 1.4e-16 60.5 0.0 1.1e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO35081.1 - 4.8e-14 52.1 0.0 8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KDO35081.1 - 6.8e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KDO35081.1 - 3.1e-05 23.5 0.0 7.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KDO35081.1 - 0.0045 17.3 0.1 0.0068 16.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KDO35081.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 KR domain AhpC-TSA PF00578.21 KDO35083.1 - 2.4e-18 66.2 0.0 3.1e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KDO35083.1 - 2.3e-07 30.5 0.0 5.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KDO35083.1 - 4.3e-07 29.7 0.0 5.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KDO35083.1 - 0.00075 19.6 0.0 0.00091 19.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Myb_DNA-binding PF00249.31 KDO35084.1 - 4.2e-11 42.9 0.0 1.3e-09 38.1 0.0 2.7 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KDO35084.1 - 2.7e-05 24.0 0.5 2.7e-05 24.0 0.5 3.4 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KDO35084.1 - 0.0016 18.6 0.4 0.007 16.6 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain LRR_6 PF13516.6 KDO35085.1 - 2.9e-18 64.3 12.8 0.0013 18.6 0.0 7.7 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KDO35085.1 - 1.4e-13 50.8 0.5 0.0021 18.4 0.0 5.2 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO35085.1 - 7.8e-06 25.6 10.9 0.065 13.0 0.2 4.4 3 2 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KDO35085.1 - 9.4e-06 25.5 6.1 4 8.4 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat PALP PF00291.25 KDO35086.1 - 3.1e-08 33.4 0.0 4e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tash_PEST PF07708.11 KDO35086.1 - 2.3 8.5 4.3 17 5.7 0.3 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Abhydrolase_1 PF00561.20 KDO35087.1 - 1.6e-13 50.9 0.0 3.5e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KDO35087.1 - 6.2e-10 38.8 0.1 1.8e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KDO35087.1 - 2.7e-07 31.4 0.0 4.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KDO35087.1 - 0.00058 19.8 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Peptidase_S15 PF02129.18 KDO35087.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 KDO35087.1 - 0.059 12.7 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) BAG PF02179.16 KDO35088.1 - 1.2e-07 32.0 0.5 1.2e-07 32.0 0.5 1.8 2 0 0 2 2 2 1 BAG domain RRN3 PF05327.11 KDO35088.1 - 0.0019 16.9 4.7 0.002 16.8 4.7 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KDO35088.1 - 0.014 14.8 9.6 0.019 14.4 9.6 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KDO35088.1 - 0.071 11.9 1.3 0.083 11.7 1.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KDO35088.1 - 0.12 11.8 7.0 0.15 11.4 7.0 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 KDO35088.1 - 0.15 11.4 13.3 0.21 10.9 13.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 KDO35088.1 - 0.18 10.0 13.5 0.23 9.6 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family FRQ PF09421.10 KDO35088.1 - 0.19 9.7 3.9 0.22 9.5 3.9 1.0 1 0 0 1 1 1 0 Frequency clock protein Zip PF02535.22 KDO35088.1 - 0.25 10.5 0.2 0.32 10.2 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 KDO35088.1 - 0.72 9.2 8.1 1 8.7 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sigma70_ner PF04546.13 KDO35088.1 - 0.84 9.5 10.6 1.6 8.6 10.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KDO35088.1 - 1.4 6.9 20.2 1.9 6.5 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 KDO35088.1 - 2.6 8.1 13.1 3.5 7.7 13.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein IFT57 PF10498.9 KDO35088.1 - 3.8 6.4 8.1 5.8 5.8 8.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PPP4R2 PF09184.11 KDO35088.1 - 6.8 6.2 14.7 9 5.8 14.7 1.1 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.11 KDO35088.1 - 9.9 4.1 6.6 13 3.7 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen STIMATE PF12400.8 KDO35089.1 - 1.6e-33 115.9 7.2 3e-33 115.1 7.2 1.4 1 0 0 1 1 1 1 STIMATE family MgtE PF01769.16 KDO35089.1 - 0.13 12.6 8.9 1.6 9.2 2.9 2.4 2 1 0 2 2 2 0 Divalent cation transporter Kinesin PF00225.23 KDO35090.1 - 7.3e-110 367.0 2.8 1.7e-109 365.8 0.3 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO35090.1 - 8.2e-28 97.2 0.0 3.1e-27 95.3 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding NPV_P10 PF05531.12 KDO35090.1 - 0.23 12.0 10.6 0.11 13.0 1.0 4.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein ResIII PF04851.15 KDO35090.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF641 PF04859.12 KDO35090.1 - 2.1 8.7 29.0 0.28 11.5 4.8 3.9 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Nas2_N PF18265.1 KDO35091.1 - 1.9e-26 91.8 0.0 2.9e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KDO35091.1 - 1.8e-06 27.7 0.1 3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO35091.1 - 2.6e-05 24.4 0.0 5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KDO35091.1 - 6.2e-05 23.3 0.0 9.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KDO35091.1 - 6.9e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Mrr_cat PF04471.12 KDO35093.1 - 2e-10 40.7 0.0 2.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease DUF2034 PF10356.9 KDO35093.1 - 7.4e-08 32.0 0.0 0.0016 17.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Dak1 PF02733.17 KDO35094.1 - 7e-106 353.6 2.6 9.4e-106 353.2 2.6 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KDO35094.1 - 1.1e-40 139.4 5.3 1.9e-40 138.6 5.3 1.4 1 0 0 1 1 1 1 DAK2 domain ATP-synt_10 PF05176.14 KDO35095.1 - 1.4e-26 93.3 0.0 1.8e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein RHS PF03527.14 KDO35095.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 RHS protein BSD PF03909.17 KDO35098.1 - 3.6e-10 39.7 1.2 1e-09 38.3 1.2 1.8 1 0 0 1 1 1 1 BSD domain SLAM PF06214.11 KDO35098.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein Peptidase_C2 PF00648.21 KDO35099.1 - 4.5e-62 209.7 0.0 3.1e-59 200.4 0.0 2.3 1 1 1 2 2 2 2 Calpain family cysteine protease EF-hand_1 PF00036.32 KDO35099.1 - 1.4e-16 58.7 0.8 0.00013 21.2 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KDO35099.1 - 9.7e-15 54.8 0.2 9.5e-09 35.6 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KDO35099.1 - 4.1e-12 45.0 0.9 0.061 13.3 0.0 4.9 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KDO35099.1 - 1.5e-09 37.6 0.3 5.6e-05 22.9 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO35099.1 - 5.4e-09 35.1 4.1 0.017 14.6 0.0 4.7 4 0 0 4 4 4 2 EF hand Calpain_III PF01067.22 KDO35099.1 - 1.5e-08 35.0 0.0 1.7e-07 31.6 0.0 2.5 1 1 0 1 1 1 1 Calpain large subunit, domain III WW PF00397.26 KDO35099.1 - 5.1e-05 23.3 0.4 0.00013 21.9 0.4 1.8 1 0 0 1 1 1 1 WW domain MIP-T3_C PF17749.1 KDO35099.1 - 0.29 11.1 3.8 0.71 9.8 3.8 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Kelch_1 PF01344.25 KDO35100.1 - 8.1e-36 121.4 8.5 4.8e-11 42.1 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KDO35100.1 - 1.7e-33 114.3 9.7 9.4e-08 32.0 0.1 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KDO35100.1 - 5.3e-32 109.5 18.3 1e-06 28.8 0.3 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO35100.1 - 3.3e-28 97.0 8.7 1.9e-07 31.1 0.3 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KDO35100.1 - 4.3e-25 87.2 13.0 5.1e-06 26.3 0.7 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KDO35100.1 - 9.7e-24 82.4 8.5 3e-07 30.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif RAG2 PF03089.14 KDO35100.1 - 0.00086 18.4 0.6 0.057 12.4 0.0 3.2 2 1 1 3 3 3 1 Recombination activating protein 2 DUF5074 PF16819.5 KDO35100.1 - 0.17 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) HELP PF03451.14 KDO35101.1 - 2.4e-62 206.7 0.7 1.2e-21 76.3 0.0 3.5 3 0 0 3 3 3 3 HELP motif WD40 PF00400.32 KDO35101.1 - 1.5e-49 164.9 103.8 4.2e-05 24.2 0.2 28.5 30 0 0 30 30 30 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35101.1 - 5.4e-22 77.9 1.7 0.0061 16.8 0.0 13.5 13 3 3 16 16 16 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO35101.1 - 0.00058 19.8 0.0 15 5.4 0.0 6.5 6 1 0 7 7 7 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KDO35101.1 - 0.0012 17.5 0.8 0.018 13.6 0.1 3.2 3 1 0 3 3 3 1 Cytochrome D1 heme domain Frtz PF11768.8 KDO35101.1 - 0.008 14.6 0.0 9.3 4.4 0.0 3.7 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF3615 PF12274.8 KDO35101.1 - 0.018 15.5 3.5 4.6 7.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3615) WD40_like PF17005.5 KDO35101.1 - 0.044 13.1 2.2 3.5 6.9 0.0 4.6 5 0 0 5 5 5 0 WD40-like domain PD40 PF07676.12 KDO35101.1 - 0.073 13.0 0.0 21 5.2 0.0 3.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EF-hand_4 PF12763.7 KDO35101.1 - 0.078 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HlyD_3 PF13437.6 KDO35102.1 - 0.1 13.3 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein MR_MLE_C PF13378.6 KDO35103.1 - 0.078 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like DUF3591 PF12157.8 KDO35104.1 - 8.6e-87 291.6 0.0 8.6e-87 291.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KDO35104.1 - 8.2e-16 57.9 0.0 2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 KDO35104.1 - 2.6e-05 23.9 0.1 6.5e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KDO35104.1 - 0.26 11.5 1.2 0.5 10.5 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Kelch_1 PF01344.25 KDO35105.1 - 2.8e-34 116.5 6.6 1.5e-08 34.0 0.2 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KDO35105.1 - 1.8e-32 111.0 17.1 1.2e-05 25.5 0.2 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KDO35105.1 - 6.3e-31 106.1 9.5 3.4e-07 30.2 0.1 6.7 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KDO35105.1 - 4.8e-27 93.3 10.2 1.5e-06 28.3 0.3 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KDO35105.1 - 8.4e-26 89.5 9.9 6.6e-06 26.0 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KDO35105.1 - 2.1e-24 84.5 7.8 3.4e-06 26.8 0.1 6.5 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.14 KDO35105.1 - 0.0023 17.0 0.1 0.017 14.1 0.0 2.5 3 1 0 3 3 3 1 Recombination activating protein 2 PCI PF01399.27 KDO35106.1 - 1.8e-15 57.3 0.0 7.5e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KDO35106.1 - 7.1e-15 54.8 4.8 2.3e-14 53.2 4.8 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PknG_TPR PF16918.5 KDO35106.1 - 0.0036 16.1 4.0 0.0063 15.3 3.9 1.4 1 1 0 1 1 1 1 Protein kinase G tetratricopeptide repeat Voldacs PF03517.13 KDO35107.1 - 1.4e-20 73.9 1.8 6.5e-10 39.3 0.0 2.3 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 KDO35107.1 - 0.0045 17.2 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Ser_hydrolase PF06821.13 KDO35108.1 - 5.4e-10 39.4 0.0 6.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 KDO35108.1 - 9.5e-06 26.4 0.3 0.00053 20.7 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF1057 PF06342.12 KDO35108.1 - 0.00032 19.8 0.0 0.00046 19.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 KDO35108.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KDO35108.1 - 0.17 11.1 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 FAD-oxidase_C PF02913.19 KDO35110.1 - 0.17 11.5 3.7 0.21 11.2 3.7 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain FAM117 PF15388.6 KDO35110.1 - 0.29 10.5 5.3 0.33 10.3 5.3 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Amnionless PF14828.6 KDO35110.1 - 2.1 7.1 5.4 2.5 6.8 5.4 1.1 1 0 0 1 1 1 0 Amnionless PDZ_6 PF17820.1 KDO35112.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO35112.1 - 0.0051 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain TTRAP PF14203.6 KDO35112.1 - 0.059 13.4 3.6 3.9 7.5 0.7 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Proteasome PF00227.26 KDO35113.1 - 1.4e-30 106.2 0.0 1.6e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-CCHC_3 PF13917.6 KDO35114.1 - 3.6e-20 71.6 1.8 8.1e-20 70.5 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle AF-4 PF05110.13 KDO35114.1 - 0.00042 18.6 29.9 0.00051 18.3 29.9 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 KDO35114.1 - 0.0055 16.5 6.7 0.0058 16.4 6.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein eIF3g PF12353.8 KDO35114.1 - 0.13 12.6 0.4 0.13 12.6 0.4 2.0 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G SPX PF03105.19 KDO35114.1 - 0.72 9.7 18.1 0.77 9.6 18.1 1.0 1 0 0 1 1 1 0 SPX domain Secretin_N_2 PF07655.13 KDO35114.1 - 1 10.0 21.3 1.5 9.4 21.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 KDO35114.1 - 1.1 7.7 16.1 1 7.8 16.1 1.0 1 0 0 1 1 1 0 Macoilin family NAM-associated PF14303.6 KDO35114.1 - 1.5 9.6 18.7 2 9.1 18.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF913 PF06025.12 KDO35114.1 - 2.5 7.0 8.8 3 6.7 8.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tmemb_cc2 PF10267.9 KDO35114.1 - 3.7 6.6 9.7 3.6 6.6 9.7 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Herpes_capsid PF06112.11 KDO35114.1 - 5.4 7.1 20.5 6.9 6.7 20.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PI3K_1B_p101 PF10486.9 KDO35114.1 - 8.9 3.9 17.8 9.8 3.8 17.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 KDO35115.1 - 4.7e-51 173.7 0.0 6e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35115.1 - 4.3e-23 81.9 0.0 9.3e-23 80.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KDO35115.1 - 3.4e-05 23.9 0.1 6.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KDO35115.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO35115.1 - 0.02 14.3 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KDO35115.1 - 0.027 13.5 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 KDO35115.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Nucleoporin_FG PF13634.6 KDO35116.1 - 3.7e-05 24.5 1.9 0.025 15.4 0.3 2.7 1 1 1 2 2 2 2 Nucleoporin FG repeat region Root_cap PF06830.11 KDO35116.1 - 0.24 11.5 0.7 0.52 10.5 0.7 1.5 1 0 0 1 1 1 0 Root cap DnaJ PF00226.31 KDO35118.1 - 4e-26 90.9 0.5 1e-25 89.6 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KDO35118.1 - 1.7e-19 70.0 0.7 3.8e-19 68.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 KDO35118.1 - 0.00066 19.6 1.3 0.0024 17.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AMP-binding PF00501.28 KDO35120.1 - 3.7e-84 282.8 0.0 4.7e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO35120.1 - 0.023 15.6 0.0 0.06 14.3 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO35122.1 - 2.5e-82 276.7 0.0 3.6e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO35122.1 - 0.0069 17.3 0.3 0.017 16.1 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KDO35123.1 - 2.4e-74 250.4 0.0 3.7e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioredoxin PF00085.20 KDO35123.1 - 1e-25 89.7 0.0 2.9e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin AMP-binding_C PF13193.6 KDO35123.1 - 0.01 16.8 0.2 0.028 15.4 0.2 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Thioredoxin_7 PF13899.6 KDO35123.1 - 0.036 14.2 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Pkinase_Tyr PF07714.17 KDO35124.1 - 5.5e-38 130.7 0.0 7.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO35124.1 - 3.3e-31 108.6 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CEP44 PF15007.6 KDO35124.1 - 0.11 12.6 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 Flavodoxin_1 PF00258.25 KDO35126.1 - 0.0092 16.2 0.0 0.015 15.5 0.0 1.2 1 1 0 1 1 1 1 Flavodoxin bZIP_1 PF00170.21 KDO35126.1 - 0.034 14.2 10.4 0.05 13.7 10.4 1.2 1 0 0 1 1 1 0 bZIP transcription factor DUF4337 PF14235.6 KDO35126.1 - 0.043 13.9 5.3 0.053 13.6 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PRA-PH PF01503.17 KDO35126.1 - 0.049 14.1 2.3 0.069 13.6 2.3 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase bZIP_2 PF07716.15 KDO35126.1 - 0.063 13.4 11.6 0.088 12.9 11.6 1.2 1 0 0 1 1 1 0 Basic region leucine zipper DUF3958 PF13125.6 KDO35127.1 - 0.0053 16.9 1.5 0.0053 16.9 1.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3958) LMBR1 PF04791.16 KDO35127.1 - 0.13 11.1 6.7 0.18 10.7 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein OS-D PF03392.13 KDO35127.1 - 0.25 11.5 3.1 0.14 12.2 0.6 2.0 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D FapA PF03961.13 KDO35127.1 - 1.3 7.5 4.4 1.8 7.1 4.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS-augmin3 PF14932.6 KDO35128.1 - 0.053 13.1 7.0 0.078 12.5 7.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF5311 PF17238.2 KDO35128.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5311) HAUS-augmin3 PF14932.6 KDO35130.1 - 0.052 13.1 6.5 0.076 12.6 6.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TSC22 PF01166.18 KDO35130.1 - 0.74 10.2 4.8 0.75 10.1 1.2 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4315 PF14193.6 KDO35130.1 - 9.2 6.4 9.0 0.31 11.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) CALM_bind PF16025.5 KDO35132.1 - 0.00093 19.6 12.4 0.0024 18.3 12.3 1.8 1 1 0 1 1 1 1 Calcium-dependent calmodulin binding T7SS_ESX_EspC PF10824.8 KDO35132.1 - 0.0021 18.5 1.4 0.0069 16.8 0.1 2.4 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm bZIP_2 PF07716.15 KDO35132.1 - 5.4 7.2 18.7 0.77 9.9 11.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_2 PF07716.15 KDO35133.1 - 0.019 15.0 6.3 0.019 15.0 6.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper T7SS_ESX_EspC PF10824.8 KDO35133.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm CALM_bind PF16025.5 KDO35133.1 - 0.41 11.2 8.6 1.6 9.2 8.6 2.2 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding Tnp_P_element PF12017.8 KDO35134.1 - 0.22 10.9 2.1 0.69 9.3 0.7 2.0 1 1 1 2 2 2 0 Transposase protein CsiV PF10972.8 KDO35135.1 - 0.0078 16.0 2.8 0.012 15.4 2.8 1.2 1 0 0 1 1 1 1 Peptidoglycan-binding protein, CsiV RCC1 PF00415.18 KDO35136.1 - 1.3e-67 224.2 13.5 3.4e-17 62.8 0.1 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO35136.1 - 7.5e-30 102.1 27.8 8.7e-08 31.8 0.4 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat KIX_2 PF16987.5 KDO35137.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 KIX domain DUF4592 PF15262.6 KDO35137.1 - 0.031 15.0 0.0 0.041 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) PapD-like PF14874.6 KDO35138.1 - 7.1e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like zf-H2C2_2 PF13465.6 KDO35140.1 - 5.6e-22 77.1 24.2 0.0021 18.4 0.4 8.1 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KDO35140.1 - 4.5e-20 70.6 50.6 0.00012 22.6 0.4 7.8 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KDO35140.1 - 2e-17 62.6 50.1 7.4e-05 23.0 0.8 7.8 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-Di19 PF05605.12 KDO35140.1 - 1.9e-09 37.6 36.7 0.0016 18.7 0.8 5.8 2 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KDO35140.1 - 7.6e-08 32.5 9.6 0.008 16.5 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KDO35140.1 - 2.3e-06 27.7 4.8 0.89 9.9 0.0 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KDO35140.1 - 3.3e-06 26.9 31.7 0.003 17.5 0.1 6.1 7 0 0 7 7 6 4 C2H2-type zinc finger zf_UBZ PF18439.1 KDO35140.1 - 5.1e-06 26.0 3.7 0.3 10.7 0.0 5.0 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KDO35140.1 - 0.00013 22.2 23.7 0.018 15.3 1.1 3.9 2 2 2 4 4 4 3 C2H2-type zinc ribbon DZR PF12773.7 KDO35140.1 - 0.0013 18.8 13.5 0.12 12.4 0.4 3.2 2 1 0 2 2 2 2 Double zinc ribbon IBR PF01485.21 KDO35140.1 - 0.0018 18.5 15.9 0.59 10.4 0.0 3.8 1 1 2 3 3 3 2 IBR domain, a half RING-finger domain zf-MYST PF17772.1 KDO35140.1 - 0.0037 16.9 10.3 0.11 12.1 0.8 4.6 4 1 0 5 5 5 1 MYST family zinc finger domain ADK_lid PF05191.14 KDO35140.1 - 0.011 15.7 16.7 0.015 15.2 1.4 4.1 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_3rep PF18868.1 KDO35140.1 - 0.011 16.4 21.6 5.4 7.7 0.8 5.5 3 2 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KDO35140.1 - 0.11 12.3 0.0 0.11 12.3 0.0 4.8 6 0 0 6 6 6 0 zinc-finger C2H2-type Ribosomal_L37ae PF01780.19 KDO35140.1 - 0.19 11.8 8.8 5.2 7.2 0.5 3.7 2 2 1 3 3 3 0 Ribosomal L37ae protein family FOXP-CC PF16159.5 KDO35140.1 - 0.77 10.4 11.8 15 6.3 0.1 4.4 3 2 1 4 4 4 0 FOXP coiled-coil domain Rubredoxin PF00301.20 KDO35140.1 - 2.4 8.3 7.6 15 5.7 0.1 4.4 5 0 0 5 5 5 0 Rubredoxin CpXC PF14353.6 KDO35140.1 - 5.2 7.1 11.7 12 6.0 0.1 3.6 2 2 1 3 3 3 0 CpXC protein Tyrosinase PF00264.20 KDO35142.1 - 3.9e-26 92.7 0.0 1.9e-25 90.5 0.0 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase RicinB_lectin_2 PF14200.6 KDO35142.1 - 0.00014 22.5 6.6 0.044 14.5 1.3 3.0 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.13 KDO35142.1 - 0.01 16.0 0.0 0.033 14.4 0.0 1.9 2 0 0 2 2 2 0 Fascin domain FRG1 PF06229.12 KDO35142.1 - 0.097 12.4 0.0 2.7 7.7 0.0 2.9 1 1 1 2 2 2 0 FRG1-like domain Tyrosinase PF00264.20 KDO35143.1 - 1.1e-26 94.5 1.1 2.9e-26 93.1 0.1 2.1 2 0 0 2 2 2 1 Common central domain of tyrosinase RicinB_lectin_2 PF14200.6 KDO35143.1 - 0.088 13.6 0.1 0.37 11.5 0.1 2.1 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like GTP-bdg_M PF16360.5 KDO35144.1 - 0.033 14.8 0.8 0.051 14.2 0.8 1.3 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Atg14 PF10186.9 KDO35144.1 - 0.05 12.7 0.4 0.059 12.5 0.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RicinB_lectin_2 PF14200.6 KDO35145.1 - 3.7e-07 30.8 3.1 0.0017 19.1 1.0 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 KDO35145.1 - 0.0019 17.9 0.0 0.33 10.7 0.0 2.7 1 1 2 3 3 3 2 FRG1-like domain Fascin PF06268.13 KDO35145.1 - 0.11 12.7 0.0 2.7 8.2 0.0 2.8 2 1 1 3 3 3 0 Fascin domain Rubredoxin_2 PF18073.1 KDO35145.1 - 2.3 8.0 8.5 2.1 8.1 0.1 3.6 4 0 0 4 4 4 0 Rubredoxin metal binding domain PH PF00169.29 KDO35146.1 - 5e-12 46.3 0.0 1.4e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 PH domain WW PF00397.26 KDO35146.1 - 0.0003 20.8 7.0 0.00061 19.8 7.0 1.6 1 0 0 1 1 1 1 WW domain PH_6 PF15406.6 KDO35146.1 - 0.025 14.8 0.0 0.16 12.2 0.0 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KDO35146.1 - 0.029 14.8 0.6 0.14 12.6 0.0 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 KDO35146.1 - 0.098 12.9 0.1 0.53 10.6 0.0 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain MBD PF01429.19 KDO35146.1 - 0.11 12.2 0.1 0.4 10.4 0.1 2.0 1 0 0 1 1 1 0 Methyl-CpG binding domain T4BSS_DotI_IcmL PF11393.8 KDO35147.1 - 0.065 12.7 1.7 12 5.4 0.1 2.9 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component DUF1087 PF06465.13 KDO35147.1 - 0.17 12.0 1.8 5 7.2 0.0 3.3 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1087) DUF3361 PF11841.8 KDO35148.1 - 4.5e-05 23.4 0.1 0.00018 21.5 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3361) PKD_channel PF08016.12 KDO35148.1 - 0.0005 18.9 1.0 0.25 10.0 1.8 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_4 PF13637.6 KDO35149.1 - 3e-13 50.0 8.6 0.0056 17.2 0.2 6.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO35149.1 - 1.3e-10 41.7 1.4 6.2e-05 23.5 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO35149.1 - 9e-07 29.1 6.0 0.026 14.8 0.0 5.3 2 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO35149.1 - 0.0019 18.5 9.8 6.1 7.8 0.0 6.3 6 1 1 7 7 7 2 Ankyrin repeat RT_RNaseH PF17917.1 KDO35149.1 - 0.024 14.9 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF5049 PF16468.5 KDO35149.1 - 0.035 14.0 0.5 7.7 6.5 0.0 4.3 6 0 0 6 6 6 0 Domain of unknown function (DUF5049) Ank_2 PF12796.7 KDO35150.1 - 2.1e-23 82.7 2.7 3.7e-05 24.2 0.1 6.4 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO35150.1 - 7.5e-11 42.3 12.4 0.22 12.2 0.0 9.2 5 4 4 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO35150.1 - 1.9e-10 40.8 11.1 4.6 7.7 0.0 9.9 6 3 5 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO35150.1 - 3.8e-08 33.0 6.2 14 6.6 0.0 9.4 11 0 0 11 11 11 2 Ankyrin repeat DUF5049 PF16468.5 KDO35150.1 - 0.19 11.6 1.4 93 3.0 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5049) Ank PF00023.30 KDO35150.1 - 0.25 11.9 5.9 1.1e+02 3.5 0.6 6.7 7 1 0 7 7 7 0 Ankyrin repeat cwf21 PF08312.12 KDO35156.1 - 1.9e-18 66.3 6.5 1.9e-18 66.3 6.5 2.2 2 1 0 2 2 2 1 cwf21 domain LAM_C PF12544.8 KDO35156.1 - 1.7 8.8 5.7 9 6.5 5.7 2.3 1 1 0 1 1 1 0 Lysine-2,3-aminomutase Ephrin_rec_like PF07699.13 KDO35157.1 - 2.9e-13 49.3 27.7 1.4e-05 24.8 1.5 4.1 1 1 4 5 5 5 5 Putative ephrin-receptor like 6PF2K PF01591.18 KDO35158.1 - 1.6e-58 197.6 0.2 3.2e-56 190.1 0.2 2.1 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KDO35158.1 - 6e-23 81.6 0.5 1.3e-22 80.5 0.5 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KDO35158.1 - 1.1e-07 32.1 0.0 2.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KDO35158.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KDO35158.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RRM_1 PF00076.22 KDO35159.1 - 4.9e-06 26.3 0.0 1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO35159.1 - 0.00029 20.9 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif TetR_C_14 PF17754.1 KDO35159.1 - 0.0031 17.4 4.6 0.0047 16.9 4.6 1.2 1 0 0 1 1 1 1 MftR C-terminal domain Pkinase PF00069.25 KDO35160.1 - 1.4e-66 224.6 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35160.1 - 5.3e-36 124.2 0.0 6.4e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO35160.1 - 4.3e-10 39.3 0.1 6.4e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO35160.1 - 2.6e-08 33.5 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO35160.1 - 3.6e-08 32.6 0.1 5.5e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KDO35160.1 - 0.00012 21.8 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KDO35160.1 - 0.0023 17.9 0.6 0.024 14.6 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KDO35160.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WaaY PF06176.11 KDO35160.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KDO35160.1 - 0.065 12.8 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RAMP4 PF06624.12 KDO35160.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 RadC PF04002.15 KDO35160.1 - 0.14 12.1 0.2 0.35 10.8 0.2 1.7 1 1 0 1 1 1 0 RadC-like JAB domain IQ PF00612.27 KDO35161.1 - 8.1e-05 22.1 2.5 8.1e-05 22.1 2.5 5.0 4 0 0 4 4 4 2 IQ calmodulin-binding motif TPR_2 PF07719.17 KDO35161.1 - 0.0004 20.3 1.0 0.13 12.4 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO35161.1 - 0.014 16.1 0.3 0.014 16.1 0.3 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KDO35162.1 - 7.2e-66 222.9 17.1 1.3e-64 218.7 17.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KDO35162.1 - 1.4e-19 70.3 55.9 1.2e-17 63.9 28.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Adeno_E3_CR2 PF02439.15 KDO35163.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MORN PF02493.20 KDO35164.1 - 3.4e-35 117.9 65.6 4.6e-07 29.3 1.0 11.1 11 0 0 11 11 11 9 MORN repeat MORN_2 PF07661.13 KDO35164.1 - 6.6 7.3 6.2 14 6.3 0.2 3.7 3 0 0 3 3 3 0 MORN repeat variant ABC2_membrane PF01061.24 KDO35165.1 - 1.5e-30 106.2 17.1 2e-30 105.8 17.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KDO35165.1 - 2.4e-26 92.9 0.0 3.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KDO35165.1 - 2.7e-08 34.0 0.3 0.0043 16.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO35165.1 - 2.9e-06 27.8 0.1 7.7e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KDO35165.1 - 9.9e-05 21.9 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KDO35165.1 - 0.0002 21.0 0.0 0.067 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KDO35165.1 - 0.00068 19.3 0.1 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KDO35165.1 - 0.0033 17.7 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KDO35165.1 - 0.0047 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 KDO35165.1 - 0.01 15.8 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KDO35165.1 - 0.02 15.4 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO35165.1 - 0.037 14.3 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KDO35165.1 - 0.051 14.1 0.0 0.085 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KDO35165.1 - 0.054 13.9 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 KDO35165.1 - 0.058 12.5 12.2 0.092 11.8 12.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF87 PF01935.17 KDO35165.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Rad17 PF03215.15 KDO35165.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 KDO35165.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KDO35165.1 - 0.13 12.2 0.1 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KDO35165.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SLBB PF10531.9 KDO35165.1 - 0.2 11.6 0.3 0.52 10.2 0.1 1.8 2 0 0 2 2 2 0 SLBB domain ABC_tran PF00005.27 KDO35166.1 - 5.6e-28 98.2 0.0 7.9e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KDO35166.1 - 4.9e-21 75.1 15.6 7.7e-21 74.5 15.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KDO35166.1 - 8.3e-08 32.4 0.1 0.007 16.2 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO35166.1 - 2e-05 25.1 0.3 5.6e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KDO35166.1 - 0.0013 19.1 0.0 0.0047 17.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KDO35166.1 - 0.0014 18.3 0.2 0.0059 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KDO35166.1 - 0.0015 18.2 0.2 0.0036 17.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KDO35166.1 - 0.0027 17.2 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KDO35166.1 - 0.0062 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KDO35166.1 - 0.024 15.2 0.0 0.039 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KDO35166.1 - 0.029 13.5 12.5 0.04 13.0 12.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 KDO35166.1 - 0.031 14.8 0.3 0.05 14.1 0.3 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KDO35166.1 - 0.044 14.0 0.8 0.14 12.4 0.3 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KDO35166.1 - 0.045 13.8 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KDO35166.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KDO35166.1 - 0.076 13.1 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain MeaB PF03308.16 KDO35166.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KDO35166.1 - 0.26 10.4 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Kinocilin PF15033.6 KDO35166.1 - 1.1 8.9 6.8 2.2 8.0 3.2 2.7 2 1 1 3 3 3 0 Kinocilin protein DUF4589 PF15252.6 KDO35167.1 - 0.084 12.9 0.6 0.082 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) MORN PF02493.20 KDO35168.1 - 6.4e-48 157.9 66.8 4.5e-07 29.4 1.0 11.3 11 0 0 11 11 11 11 MORN repeat Nop14 PF04147.12 KDO35169.1 - 1.5 7.0 6.4 1.8 6.7 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.13 KDO35169.1 - 2.2 6.3 11.0 3.4 5.7 11.0 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SDA1 PF05285.12 KDO35169.1 - 3 7.2 6.9 3.7 6.9 6.9 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KDO35169.1 - 8.3 4.4 9.1 10 4.1 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CTP_transf_1 PF01148.20 KDO35170.1 - 3.1e-42 145.2 10.8 3.9e-42 144.8 10.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 KDO35170.1 - 0.0075 16.3 0.5 0.018 15.0 0.2 1.8 1 1 0 1 1 1 1 CDP-archaeol synthase Nucleoporin_FG2 PF15967.5 KDO35170.1 - 0.39 9.2 1.4 0.57 8.6 1.4 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF2749 PF10907.8 KDO35173.1 - 0.072 13.3 1.2 0.13 12.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) LRR_8 PF13855.6 KDO35174.1 - 0.035 13.9 6.9 4.7 7.1 0.0 4.4 3 2 1 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 KDO35174.1 - 0.27 11.4 18.4 1.3 9.2 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat LEM PF03020.15 KDO35175.1 - 0.075 12.6 0.3 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 LEM domain Nodulin PF02451.15 KDO35175.1 - 2.7 7.4 5.1 5.7 6.4 5.1 1.4 1 0 0 1 1 1 0 Nodulin PDZ_6 PF17820.1 KDO35176.1 - 3.3e-08 33.2 0.0 0.00086 19.1 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KDO35176.1 - 1.4e-07 31.7 0.0 0.0028 18.0 0.0 2.2 1 1 1 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KDO35176.1 - 0.0023 18.2 0.0 0.097 13.0 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Gram_pos_anchor PF00746.21 KDO35177.1 - 0.0017 18.3 0.6 0.0034 17.3 0.6 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Trp_oprn_chp PF09534.10 KDO35177.1 - 0.022 14.6 1.5 0.047 13.5 1.5 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 KDO35177.1 - 0.096 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Fusion_gly PF00523.18 KDO35178.1 - 0.14 10.4 0.6 0.19 9.9 0.6 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF4131 PF13567.6 KDO35178.1 - 0.18 11.5 0.4 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Wzz PF02706.15 KDO35178.1 - 0.19 12.0 0.0 0.36 11.2 0.0 1.3 1 0 0 1 1 1 0 Chain length determinant protein Yip1 PF04893.17 KDO35181.1 - 0.012 15.4 0.9 0.022 14.5 0.2 1.7 2 0 0 2 2 2 0 Yip1 domain DUF2076 PF09849.9 KDO35181.1 - 0.14 12.2 7.5 0.21 11.6 7.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2157 PF09925.9 KDO35181.1 - 0.16 11.7 2.0 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) CYSTM PF12734.7 KDO35181.1 - 0.34 11.3 0.0 0.34 11.3 0.0 4.6 3 1 1 4 4 4 0 Cysteine-rich TM module stress tolerance Keratin_2_head PF16208.5 KDO35181.1 - 2.2 8.4 16.6 4.2 7.5 16.6 1.4 1 0 0 1 1 1 0 Keratin type II head DUF4131 PF13567.6 KDO35181.1 - 5.1 6.7 5.8 12 5.5 1.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3482 PF11981.8 KDO35181.1 - 8.3 5.7 10.3 11 5.3 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) PXPV PF12778.7 KDO35182.1 - 0.0012 18.7 8.9 0.0012 18.7 8.9 2.5 2 0 0 2 2 2 1 PXPV repeat (3 copies) DUF2076 PF09849.9 KDO35182.1 - 0.35 10.9 4.0 0.45 10.5 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Keratin_2_head PF16208.5 KDO35182.1 - 7.3 6.7 16.5 11 6.1 16.5 1.3 1 0 0 1 1 1 0 Keratin type II head PX PF00787.24 KDO35183.1 - 0.00017 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 PX domain DPM3 PF08285.11 KDO35184.1 - 0.00063 19.9 0.2 0.0011 19.2 0.1 1.5 1 1 1 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF997 PF06196.12 KDO35184.1 - 0.11 12.6 1.8 0.17 11.9 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF997) STAS_2 PF13466.6 KDO35185.1 - 5.4 7.4 11.2 0.23 11.8 2.9 2.6 3 0 0 3 3 3 0 STAS domain SNF2_N PF00176.23 KDO35187.1 - 7.5e-44 149.9 0.1 1.5e-43 148.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KDO35187.1 - 1.9e-15 57.1 0.0 3.4e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.8 KDO35187.1 - 3.1e-12 46.5 0.5 5.7e-12 45.6 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) HEAT PF02985.22 KDO35187.1 - 0.0043 17.2 11.9 0.42 11.0 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat SWI2_SNF2 PF18766.1 KDO35187.1 - 0.04 13.6 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KDO35187.1 - 0.046 12.9 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEAT_2 PF13646.6 KDO35187.1 - 1.3 9.5 27.7 0.071 13.5 0.5 6.4 5 2 3 8 8 8 0 HEAT repeats Swi3 PF07962.12 KDO35188.1 - 0.13 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Pkinase PF00069.25 KDO35189.1 - 5e-71 239.1 0.0 6.8e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35189.1 - 2.5e-38 131.9 0.0 3.6e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KDO35189.1 - 1.9e-36 124.0 0.1 6.4e-19 67.9 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KDO35189.1 - 1.8e-05 24.2 0.0 3.7e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KDO35189.1 - 2.5e-05 23.2 0.0 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KDO35189.1 - 0.0011 18.9 2.0 0.0053 16.7 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF4524 PF15025.6 KDO35189.1 - 0.004 16.9 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4524) Lipase_GDSL_2 PF13472.6 KDO35192.1 - 5.7e-22 79.0 0.1 7.9e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KDO35192.1 - 3.7e-10 40.1 0.0 8.5e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SH3_11 PF18103.1 KDO35192.1 - 0.023 14.8 0.7 0.056 13.6 0.7 1.6 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain DUF459 PF04311.13 KDO35192.1 - 0.038 13.0 0.1 0.31 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF459) Peptidase_C1 PF00112.23 KDO35193.1 - 1.1e-53 182.6 0.7 1.1e-53 182.6 0.7 1.8 2 0 0 2 2 2 1 Papain family cysteine protease Ricin_B_lectin PF00652.22 KDO35193.1 - 6.5e-24 84.6 12.3 2e-13 50.7 1.6 2.7 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KDO35193.1 - 0.0008 19.0 0.9 0.76 9.4 0.1 2.8 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain TRP PF06011.12 KDO35195.1 - 1.8e-15 56.7 31.2 7.1e-15 54.7 31.2 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Ferric_reduct PF01794.19 KDO35197.1 - 3.9e-16 59.3 8.5 3.9e-16 59.3 8.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO35197.1 - 1.6e-11 44.6 0.0 2.2e-06 27.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DOMON PF03351.17 KDO35197.1 - 3.9e-09 36.8 0.0 6.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 DOMON domain FAD_binding_8 PF08022.12 KDO35197.1 - 1.7e-08 34.5 0.0 3.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KDO35197.1 - 7.3e-06 26.6 0.0 1.8e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TMEM125 PF15109.6 KDO35197.1 - 0.055 13.8 1.2 0.49 10.7 0.4 2.9 2 0 0 2 2 2 0 TMEM125 protein family Pkinase PF00069.25 KDO35198.1 - 7.1e-70 235.4 0.0 8.2e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35198.1 - 6.6e-30 104.2 0.0 8.8e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO35198.1 - 0.0028 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO35198.1 - 0.015 15.3 0.1 0.026 14.4 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KDO35198.1 - 0.02 14.2 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO35198.1 - 0.03 13.4 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 KDO35199.1 - 2.3e-08 34.5 6.2 1.3e-05 25.9 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L40e PF01020.17 KDO35200.1 - 4e-29 100.3 10.7 4.3e-29 100.1 10.7 1.0 1 0 0 1 1 1 1 Ribosomal L40e family Ferric_reduct PF01794.19 KDO35201.1 - 2.5e-15 56.7 8.9 2.5e-15 56.7 8.9 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KDO35201.1 - 1.3e-12 48.1 0.0 2.3e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DOMON PF03351.17 KDO35201.1 - 9.5e-12 45.2 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 DOMON domain NAD_binding_1 PF00175.21 KDO35201.1 - 6.4e-08 33.2 0.0 1.8e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KDO35201.1 - 6e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_4 PF01565.23 KDO35202.1 - 1.1e-21 77.0 0.3 2.1e-21 76.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KDO35202.1 - 3.2e-05 24.0 0.1 6.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KDO35203.1 - 1.8e-22 79.6 0.1 3.6e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KDO35203.1 - 3.1e-06 27.2 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ERG2_Sigma1R PF04622.12 KDO35203.1 - 0.036 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein AAA_22 PF13401.6 KDO35204.1 - 3.9e-09 36.9 0.0 1.2e-06 28.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KDO35204.1 - 1.1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KDO35204.1 - 1.2e-06 29.0 0.6 5.7e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 KDO35204.1 - 0.00095 19.1 0.0 0.0091 15.9 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KDO35204.1 - 0.08 13.3 0.6 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MitMem_reg PF13012.6 KDO35205.1 - 2.9e-34 117.8 0.7 5.9e-34 116.9 0.7 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KDO35205.1 - 9.9e-26 90.0 0.0 1.8e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rab5-bind PF09311.11 KDO35205.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Rabaptin-like protein HMMR_N PF15905.5 KDO35206.1 - 0.0003 20.4 4.7 0.0003 20.4 4.7 1.8 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4559 PF15112.6 KDO35206.1 - 0.0017 18.1 3.4 0.0031 17.3 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) Baculo_PEP_C PF04513.12 KDO35206.1 - 0.016 15.3 0.4 0.045 13.8 0.0 1.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.12 KDO35206.1 - 0.036 14.7 5.3 6.4 7.4 2.6 2.9 2 1 0 2 2 2 0 Striatin family Astro_capsid_p PF12226.8 KDO35206.1 - 0.97 8.5 13.9 1.5 7.9 13.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SEEEED PF14797.6 KDO35206.1 - 4.5 7.4 18.8 0.93 9.7 15.0 1.8 1 1 1 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex ADIP PF11559.8 KDO35206.1 - 6.7 6.8 9.9 6.2 6.9 1.6 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2457 PF10446.9 KDO35206.1 - 9.5 5.2 16.7 13 4.8 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EF-hand_1 PF00036.32 KDO35207.1 - 1.6e-05 24.1 0.1 0.00022 20.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KDO35207.1 - 0.00067 19.4 0.2 0.0068 16.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KDO35207.1 - 0.0027 17.1 0.1 0.011 15.2 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KDO35207.1 - 0.0079 16.1 0.2 0.49 10.4 0.0 3.3 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF3573 PF12097.8 KDO35207.1 - 0.07 11.9 0.5 0.14 10.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Caldesmon PF02029.15 KDO35207.1 - 0.11 11.3 1.5 0.23 10.2 1.5 1.5 1 0 0 1 1 1 0 Caldesmon EF-hand_7 PF13499.6 KDO35207.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF4489 PF14879.6 KDO35207.1 - 0.15 12.2 0.3 0.28 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) TerB PF05099.13 KDO35207.1 - 0.53 10.2 0.0 0.53 10.2 0.0 3.3 4 0 0 4 4 4 0 Tellurite resistance protein TerB DXP_reductoisom PF02670.16 KDO35207.1 - 1.6 9.4 4.2 20 5.9 0.0 2.8 3 0 0 3 3 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TSC22 PF01166.18 KDO35207.1 - 3.6 8.0 11.0 6.1 7.2 1.5 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family Spc24 PF08286.11 KDO35207.1 - 6.2 7.1 12.0 1.4 9.2 0.7 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DEAD PF00270.29 KDO35208.1 - 3.7e-38 131.0 0.0 1.1e-37 129.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO35208.1 - 1.8e-23 83.0 0.0 3.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KDO35208.1 - 0.0039 17.5 0.0 0.042 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 KDO35208.1 - 0.005 16.1 0.0 0.0071 15.6 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KDO35208.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Chlamy_scaf PF09675.10 KDO35208.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) CMS1 PF14617.6 KDO35208.1 - 0.17 11.2 0.2 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Peripla_BP_3 PF13377.6 KDO35209.1 - 0.18 12.1 3.9 0.35 11.2 3.9 1.5 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Glyco_hydro_14 PF01373.17 KDO35210.1 - 3.1e-91 306.3 0.0 3.8e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 AP_endonuc_2 PF01261.24 KDO35210.1 - 0.073 12.5 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel CPSase_L_D2 PF02786.17 KDO35211.1 - 4.7e-78 261.5 0.1 7.9e-78 260.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KDO35211.1 - 7.9e-44 148.7 1.0 2e-43 147.4 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KDO35211.1 - 1.2e-35 121.9 0.0 5.2e-35 119.8 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KDO35211.1 - 2.8e-17 62.3 1.9 8e-17 60.8 1.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 KDO35211.1 - 7.6e-13 48.9 0.0 2.8e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 KDO35211.1 - 2.5e-08 33.7 0.1 5.5e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KDO35211.1 - 8.1e-08 32.0 0.1 2.7e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KDO35211.1 - 0.0065 16.3 0.2 0.018 14.9 0.2 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_5 PF13549.6 KDO35211.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KDO35211.1 - 0.012 14.9 0.0 0.038 13.2 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 KDO35211.1 - 0.029 14.3 0.7 0.064 13.2 0.7 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain VWA PF00092.28 KDO35212.1 - 2.5e-24 86.5 0.0 1.1e-23 84.4 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KDO35212.1 - 1.2e-15 57.8 0.2 2.2e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KDO35212.1 - 1.6e-11 44.8 0.1 4.5e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KDO35212.1 - 6.5e-05 22.4 0.4 0.0002 20.8 0.0 2.0 2 1 0 2 2 2 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 KDO35212.1 - 0.015 15.5 0.1 0.096 12.8 0.0 2.2 2 0 0 2 2 2 0 VWA-like domain (DUF2201) Vwaint PF14624.6 KDO35212.1 - 0.031 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 VWA / Hh protein intein-like COOH-NH2_lig PF14395.6 KDO35212.1 - 0.16 11.2 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 HTH_6 PF01418.17 KDO35213.1 - 0.93 9.5 3.6 0.92 9.5 0.5 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF4392 PF14336.6 KDO35214.1 - 6.1e-72 242.6 0.3 9.9e-72 241.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) FH2 PF02181.23 KDO35215.1 - 1.7e-91 307.1 0.1 1.7e-91 307.1 0.1 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 KDO35215.1 - 1e-32 113.7 30.4 2.6e-12 47.4 0.0 5.2 5 1 0 5 5 4 3 Subunit CCDC53 of WASH complex FYVE PF01363.21 KDO35215.1 - 4.2e-09 36.4 13.5 1.4e-08 34.8 13.5 1.8 1 1 0 1 1 1 1 FYVE zinc finger zinc_ribbon_2 PF13240.6 KDO35215.1 - 2.3e-05 23.9 2.9 8.2e-05 22.2 2.9 2.0 1 0 0 1 1 1 1 zinc-ribbon domain Pex24p PF06398.11 KDO35215.1 - 0.00043 19.4 0.0 0.00084 18.4 0.0 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FYVE_2 PF02318.16 KDO35215.1 - 0.00054 20.2 4.8 0.00054 20.2 4.8 3.2 4 0 0 4 4 3 1 FYVE-type zinc finger DZR PF12773.7 KDO35215.1 - 0.002 18.1 10.0 0.15 12.1 10.0 2.6 1 1 0 1 1 1 1 Double zinc ribbon TolA_bind_tri PF16331.5 KDO35215.1 - 0.36 10.9 4.5 2.8 8.1 0.7 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation Hemerythrin PF01814.23 KDO35215.1 - 0.48 11.0 2.6 1.3 9.7 0.1 3.0 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain HIP1_clath_bdg PF16515.5 KDO35215.1 - 1.6 9.4 7.8 22 5.7 0.0 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KDO35215.1 - 2.7 7.2 9.0 5.4 6.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) C1_1 PF00130.22 KDO35215.1 - 3.9 7.4 13.2 1.7 8.6 5.3 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SKA2 PF16740.5 KDO35215.1 - 5.4 6.8 7.7 8.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Ricin_B_lectin PF00652.22 KDO35216.1 - 1.5e-20 73.7 16.8 6.8e-09 36.1 3.7 3.3 3 0 0 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KDO35216.1 - 1.4e-10 41.8 17.4 0.013 16.3 4.6 4.6 3 2 0 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KDO35216.1 - 6.4e-06 25.8 3.0 0.059 13.0 0.2 2.5 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain cNMP_binding PF00027.29 KDO35217.1 - 2.2e-42 143.0 0.0 9.2e-21 73.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PX PF00787.24 KDO35218.1 - 2.3e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 PX domain DEAD PF00270.29 KDO35219.1 - 4.6e-45 153.5 0.0 8e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO35219.1 - 5.4e-27 94.3 0.1 5e-26 91.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO35219.1 - 8.8e-05 22.6 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GUCT PF08152.12 KDO35219.1 - 0.026 14.8 0.0 0.091 13.1 0.0 2.0 1 0 0 1 1 1 0 GUCT (NUC152) domain SWI2_SNF2 PF18766.1 KDO35219.1 - 0.044 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase V_ATPase_prox PF18274.1 KDO35219.1 - 0.079 12.9 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe CMS1 PF14617.6 KDO35219.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NTF2 PF02136.20 KDO35220.1 - 0.042 14.4 0.3 20 5.8 0.3 2.9 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Nop14 PF04147.12 KDO35221.1 - 2.3 6.3 3.9 2.5 6.2 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family HSP70 PF00012.20 KDO35222.1 - 1.5e-266 885.4 7.0 1.7e-266 885.2 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO35222.1 - 3.5e-15 55.7 0.1 3.4e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KDO35222.1 - 0.0075 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KDO35222.1 - 0.021 13.9 0.4 0.13 11.2 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Raco_middle PF17651.1 KDO35222.1 - 0.025 14.2 0.5 9 6.0 0.0 3.6 3 1 1 4 4 4 0 RACo middle region Methyltrn_RNA_3 PF02598.17 KDO35223.1 - 2.6e-85 286.4 0.3 3.5e-85 286.0 0.0 1.3 2 0 0 2 2 2 1 Putative RNA methyltransferase Pap_E4 PF02711.14 KDO35223.1 - 8.4 7.4 0.0 8.4 7.4 0.0 3.4 3 0 0 3 3 3 0 E4 protein HlyIII PF03006.20 KDO35225.1 - 4.6e-60 203.1 23.6 2.4e-59 200.8 23.6 1.9 1 1 0 1 1 1 1 Haemolysin-III related BT1 PF03092.16 KDO35225.1 - 9.1 4.4 11.1 14 3.8 11.1 1.2 1 0 0 1 1 1 0 BT1 family Filament PF00038.21 KDO35226.1 - 0.0032 17.1 4.5 0.0032 17.1 4.5 2.9 2 1 1 3 3 3 1 Intermediate filament protein MscS_porin PF12795.7 KDO35226.1 - 0.13 11.8 23.3 0.13 11.7 11.5 2.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain RseA_C PF03873.13 KDO35226.1 - 0.19 12.0 7.4 0.82 10.0 6.4 2.6 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain DUF5082 PF16888.5 KDO35226.1 - 8.6 6.7 10.7 1.3 9.3 2.1 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF5082) DUF4047 PF13256.6 KDO35226.1 - 8.7 6.6 9.4 1.2 9.3 0.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4047) Fib_alpha PF08702.10 KDO35226.1 - 8.9 6.5 19.3 0.81 9.9 1.4 4.3 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family zf-RVT PF13966.6 KDO35227.1 - 3e-05 24.7 0.1 4.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase WD40 PF00400.32 KDO35228.1 - 1.8e-26 91.8 29.6 0.00012 22.8 0.1 12.3 13 0 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35228.1 - 1.9e-06 28.1 0.0 2.1 8.7 0.0 5.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 KDO35228.1 - 0.00044 19.6 0.1 0.0015 18.0 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KDO35228.1 - 0.0031 17.9 0.1 0.011 16.1 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KDO35228.1 - 0.0036 16.7 0.1 0.01 15.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KDO35228.1 - 0.019 14.8 0.1 0.066 13.2 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain TPR_12 PF13424.6 KDO35229.1 - 2.8e-41 139.7 13.4 6.3e-13 48.8 0.0 5.1 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KDO35229.1 - 1.1e-28 98.2 14.5 2.1e-07 30.6 0.1 7.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KDO35229.1 - 3.4e-13 48.8 8.0 0.00063 19.5 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KDO35229.1 - 7.3e-11 41.3 6.3 0.0054 16.8 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO35229.1 - 1.5e-07 30.9 8.0 0.16 12.0 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KDO35229.1 - 4.3e-07 29.6 3.9 0.096 13.0 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KDO35229.1 - 4e-06 27.4 0.6 0.36 11.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO35229.1 - 0.0001 22.8 4.2 5.2 8.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KDO35229.1 - 0.0055 16.4 11.3 1.7 8.4 0.0 5.0 6 0 0 6 6 6 2 TPR repeat TPR_6 PF13174.6 KDO35229.1 - 0.0076 16.8 7.0 6.4 7.6 0.0 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KDO35229.1 - 0.02 15.3 2.1 7.3 7.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MOR2-PAG1_C PF14225.6 KDO35229.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.4 1 1 0 1 1 1 0 Cell morphogenesis C-terminal Osmo_CC PF08946.10 KDO35229.1 - 0.026 14.8 0.1 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil LANC_like PF05147.13 KDO35229.1 - 0.043 12.4 0.1 0.057 12.0 0.1 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PPR PF01535.20 KDO35229.1 - 0.061 13.6 0.8 13 6.3 0.0 3.5 4 0 0 4 4 3 0 PPR repeat DUF4404 PF14357.6 KDO35229.1 - 0.069 13.8 0.1 7.2 7.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) MIT PF04212.18 KDO35229.1 - 0.085 12.9 0.3 4.6 7.4 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NB-LRR PF12061.8 KDO35229.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Late blight resistance protein R1 TPR_3 PF07720.12 KDO35229.1 - 0.15 12.1 2.2 3.3 7.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KDO35229.1 - 0.26 11.4 2.6 2.2 8.4 0.2 3.1 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 KDO35229.1 - 0.29 11.9 3.3 79 4.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KDO35229.1 - 3.1 7.9 6.4 2.4 8.3 0.1 3.3 4 0 0 4 4 4 0 Exonuclease VII small subunit Tmemb_185A PF10269.9 KDO35230.1 - 0.00036 20.3 4.2 0.00036 20.3 4.2 2.4 2 1 1 3 3 3 1 Transmembrane Fragile-X-F protein MRF_C2 PF13888.6 KDO35230.1 - 0.21 11.5 0.7 0.34 10.8 0.7 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 PHD PF00628.29 KDO35231.1 - 1.6e-09 37.5 7.9 1.6e-09 37.5 7.9 4.1 3 1 1 4 4 4 1 PHD-finger zf-RING_2 PF13639.6 KDO35231.1 - 0.0017 18.6 11.3 0.0017 18.6 11.3 4.2 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 KDO35231.1 - 0.0018 18.1 9.3 0.0018 18.1 9.3 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) 3Beta_HSD PF01073.19 KDO35236.1 - 2.9e-21 75.7 0.0 3.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KDO35236.1 - 4.8e-20 72.1 0.1 6.2e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KDO35236.1 - 1.3e-14 54.4 0.0 2.5e-14 53.4 0.0 1.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KDO35236.1 - 3.9e-12 46.4 0.9 6.5e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KDO35236.1 - 1.3e-10 40.8 0.2 6.8e-10 38.5 0.2 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KDO35236.1 - 3.4e-07 30.1 0.3 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KDO35236.1 - 4.5e-05 23.0 0.1 0.00023 20.7 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KDO35236.1 - 6.5e-05 22.9 0.1 0.00018 21.5 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KDO35236.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO35236.1 - 0.024 13.8 0.5 0.3 10.2 0.1 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain Glyco_hydro81C PF17652.1 KDO35237.1 - 6.8e-116 387.3 2.7 1e-115 386.8 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KDO35237.1 - 6.9e-40 137.2 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain 3Beta_HSD PF01073.19 KDO35238.1 - 1e-19 70.6 0.0 1.3e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KDO35238.1 - 2.4e-17 63.2 0.0 3.8e-17 62.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KDO35238.1 - 1.9e-14 53.4 0.0 7.3e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KDO35238.1 - 9.8e-14 51.5 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KDO35238.1 - 2.2e-11 44.0 0.0 3.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KDO35238.1 - 5.6e-07 29.6 0.1 1.3e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KDO35238.1 - 3.6e-06 26.7 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KDO35238.1 - 3.9e-05 23.2 0.0 7.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KDO35238.1 - 0.0042 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KDO35238.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NSs PF11073.8 KDO35242.1 - 0.0052 16.3 0.2 0.75 9.2 0.0 2.2 2 0 0 2 2 2 2 Rift valley fever virus non structural protein (NSs) like Gp_dh_C PF02800.20 KDO35245.1 - 1.1e-65 220.0 0.0 1.6e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KDO35245.1 - 5.8e-39 132.5 0.1 3.1e-38 130.2 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KDO35245.1 - 0.097 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RII_binding_1 PF10522.9 KDO35245.1 - 0.099 12.9 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 RII binding domain UCH PF00443.29 KDO35246.1 - 9.5e-09 35.1 0.0 6.5e-06 25.8 0.0 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO35246.1 - 0.032 13.8 0.5 0.11 12.0 0.1 1.9 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase T7SS_ESX1_EccB PF05108.13 KDO35246.1 - 0.057 12.1 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B RNA_pol_Rpb2_4 PF04566.13 KDO35247.1 - 0.062 13.6 0.1 0.087 13.1 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Epimerase PF01370.21 KDO35249.1 - 2.4e-20 73.0 0.0 3.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KDO35249.1 - 3e-19 69.1 0.0 4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KDO35249.1 - 9.5e-13 48.2 0.0 1.4e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KDO35249.1 - 3.1e-12 46.8 0.0 5.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KDO35249.1 - 1.7e-10 40.5 0.1 7.4e-10 38.4 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KDO35249.1 - 5.6e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KDO35249.1 - 4.7e-05 23.4 0.1 0.00012 22.0 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KDO35249.1 - 0.00014 21.4 0.1 0.00053 19.5 0.0 2.0 1 1 1 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KDO35249.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HOOK PF05622.12 KDO35250.1 - 1.2e-16 60.1 56.5 1.2e-16 60.1 56.5 3.8 1 1 2 3 3 3 2 HOOK protein HemN_C PF06969.16 KDO35250.1 - 0.21 11.7 8.9 0.071 13.2 1.0 3.7 3 0 0 3 3 3 0 HemN C-terminal domain GCR PF02155.15 KDO35250.1 - 1.9 7.5 13.2 1.1 8.2 1.5 3.5 1 1 1 3 3 3 0 Glucocorticoid receptor PLAC8 PF04749.17 KDO35251.1 - 2.1e-20 73.5 12.5 2.8e-20 73.1 12.5 1.2 1 0 0 1 1 1 1 PLAC8 family ARF7EP_C PF14949.6 KDO35251.1 - 0.0068 17.0 0.3 0.0068 17.0 0.3 1.6 2 0 0 2 2 2 1 ARF7 effector protein C-terminus Phage_holin_3_6 PF07332.11 KDO35251.1 - 0.044 13.8 1.4 0.06 13.4 1.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 KDO35253.1 - 9.7e-53 179.2 0.0 2.3e-52 178.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35253.1 - 1.2e-21 77.2 0.4 8.1e-21 74.5 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KDO35253.1 - 0.00063 18.8 0.2 0.0015 17.6 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KDO35253.1 - 0.0041 16.5 0.2 0.021 14.1 0.2 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KDO35253.1 - 0.0099 15.3 0.4 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KDO35253.1 - 0.039 13.0 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KDO35253.1 - 0.055 13.4 0.3 0.66 9.9 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KDO35253.1 - 0.087 13.5 0.2 0.25 12.1 0.2 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Lge1 PF11488.8 KDO35253.1 - 2.2 8.5 7.3 2.4e+02 2.0 7.3 2.6 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 HTH_Tnp_Tc3_1 PF11427.8 KDO35255.1 - 1.2e-09 37.9 0.2 5.5e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 Tc3 transposase HTH_38 PF13936.6 KDO35255.1 - 1.3e-06 28.1 0.9 1.3e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KDO35255.1 - 3e-06 26.8 1.1 0.0025 17.6 0.0 2.4 2 1 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 KDO35255.1 - 8.5e-05 23.1 0.2 0.001 19.6 0.2 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KDO35255.1 - 0.0081 16.3 1.1 3.2 7.9 0.2 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain Dimerisation PF08100.11 KDO35255.1 - 0.021 14.9 0.6 0.054 13.5 0.3 1.8 2 0 0 2 2 2 0 Dimerisation domain HTH_7 PF02796.15 KDO35255.1 - 0.09 12.9 1.0 4.8 7.4 0.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase ABC_tran PF00005.27 KDO35256.1 - 1.3e-38 132.6 0.0 8.2e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KDO35256.1 - 4.8e-37 128.1 1.4 1.7e-24 86.9 0.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KDO35256.1 - 2.3e-05 23.9 0.0 3.3 7.1 0.0 3.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KDO35256.1 - 2.5e-05 23.9 0.1 0.33 10.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KDO35256.1 - 0.0013 18.9 0.3 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KDO35256.1 - 0.0018 18.3 0.2 0.036 14.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KDO35256.1 - 0.0031 17.8 2.9 3.3 8.0 0.1 3.2 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KDO35256.1 - 0.0053 16.1 0.1 0.89 8.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KDO35256.1 - 0.0056 16.6 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KDO35256.1 - 0.0083 16.0 7.1 1.2 8.9 0.1 4.1 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4536 PF15055.6 KDO35256.1 - 0.028 14.7 0.1 0.12 12.7 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) AAA_33 PF13671.6 KDO35256.1 - 0.065 13.4 4.0 0.36 11.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KDO35256.1 - 0.13 12.8 0.0 4.6 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KDO35256.1 - 0.15 12.0 1.1 12 5.8 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 KDO35256.1 - 0.46 10.9 9.3 2.5 8.4 0.0 4.0 4 0 0 4 4 3 0 AAA ATPase domain DUF87 PF01935.17 KDO35256.1 - 1 9.4 2.0 6.1 6.9 0.7 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain RRM_1 PF00076.22 KDO35258.1 - 6.9e-30 102.7 1.2 2.2e-14 53.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO35258.1 - 1.9e-06 27.5 0.0 0.048 13.3 0.0 2.1 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KDO35258.1 - 1.6e-05 24.9 0.4 0.0011 18.9 0.1 2.4 2 0 0 2 2 2 1 Limkain b1 RRM_occluded PF16842.5 KDO35258.1 - 0.013 15.3 0.0 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KDO35258.1 - 0.065 13.2 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KDO35260.1 - 1.3e-16 60.2 0.0 2.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KDO35260.1 - 1.4e-08 34.4 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEM4 PF02602.15 KDO35261.1 - 1.9e-30 105.9 2.5 2.6e-30 105.5 2.5 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD RecA_dep_nuc PF16786.5 KDO35261.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease TMEM154 PF15102.6 KDO35262.1 - 0.0051 16.7 1.4 0.0051 16.7 1.4 3.1 3 1 1 4 4 4 1 TMEM154 protein family DUF4366 PF14283.6 KDO35262.1 - 0.15 12.1 2.4 0.35 10.9 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Podoplanin PF05808.11 KDO35262.1 - 2.1 8.4 13.2 0.5 10.4 8.7 2.2 2 0 0 2 2 2 0 Podoplanin ATP1G1_PLM_MAT8 PF02038.16 KDO35263.1 - 0.41 10.1 1.3 0.64 9.5 1.3 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Formyl_trans_N PF00551.19 KDO35264.1 - 1.7e-24 86.6 0.0 2.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KDO35264.1 - 2.8e-12 46.8 0.0 4.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF2183 PF09949.9 KDO35265.1 - 0.0015 18.9 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) YfhO PF09586.10 KDO35265.1 - 2.7 6.1 7.8 4.2 5.5 7.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Peptidase_M3 PF01432.20 KDO35266.1 - 4.6e-122 408.6 0.0 5.6e-122 408.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KDO35266.1 - 0.054 13.1 0.4 0.098 12.3 0.4 1.3 1 0 0 1 1 1 0 Peptidase M50B-like NUDIX PF00293.28 KDO35267.1 - 4.3e-10 39.7 0.0 6.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Gon7 PF08738.10 KDO35268.1 - 0.011 15.8 0.2 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Gon7 family DUF2142 PF09913.9 KDO35268.1 - 0.11 11.3 0.0 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) ZapB PF06005.12 KDO35268.1 - 0.19 12.2 2.6 0.46 11.0 2.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB BLM10_mid PF16507.5 KDO35269.1 - 9e-42 143.4 0.0 9.3e-41 140.0 0.0 2.0 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KDO35269.1 - 3.1e-26 91.1 0.4 2.4e-25 88.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KDO35269.1 - 0.66 10.4 8.3 87 3.8 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat Metallophos PF00149.28 KDO35270.1 - 1.9e-36 126.5 0.1 2.5e-36 126.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KDO35270.1 - 1.8e-16 60.3 0.5 3.8e-16 59.2 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Acyltransferase PF01553.21 KDO35271.1 - 1.5e-13 50.5 0.0 1.5e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Med9 PF07544.13 KDO35271.1 - 0.018 15.1 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ubiquitin PF00240.23 KDO35272.1 - 1.1e-16 60.3 0.0 2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KDO35272.1 - 2.1e-06 27.5 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KDO35272.1 - 0.0011 19.0 0.0 0.0032 17.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KDO35272.1 - 0.026 15.1 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 KDO35272.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KDO35272.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF962 PF06127.11 KDO35273.1 - 3.9e-24 84.5 1.6 3.1e-23 81.7 1.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Sas10_Utp3 PF04000.15 KDO35274.1 - 7.7e-09 36.1 0.4 7.7e-09 36.1 0.4 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TetR_C_30 PF17939.1 KDO35274.1 - 0.036 14.3 0.0 0.081 13.1 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AIF_C PF14721.6 KDO35274.1 - 2.3 8.6 5.4 2.1 8.7 4.2 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex2_Pex12 PF04757.14 KDO35275.1 - 3.8e-22 79.0 0.6 6.1e-22 78.3 0.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KDO35275.1 - 5.3e-09 35.8 10.9 8.7e-09 35.1 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KDO35275.1 - 9.7e-09 35.4 14.6 1.6e-08 34.7 14.6 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KDO35275.1 - 1.5e-08 34.3 11.1 2.6e-08 33.6 11.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KDO35275.1 - 6e-08 32.4 14.0 1e-07 31.7 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO35275.1 - 1.1e-07 31.6 12.6 1.9e-07 30.8 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KDO35275.1 - 2e-05 24.5 12.4 7.5e-05 22.7 12.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KDO35275.1 - 2e-05 24.4 11.0 3.8e-05 23.6 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KDO35275.1 - 5.5e-05 23.4 10.8 0.00011 22.5 10.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KDO35275.1 - 0.00052 20.1 11.3 0.00065 19.8 9.6 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KDO35275.1 - 0.1 12.7 4.9 0.26 11.4 4.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KDO35275.1 - 0.36 11.0 10.6 0.67 10.1 10.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KDO35275.1 - 1 9.3 6.6 1.9 8.4 6.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ABC2_membrane PF01061.24 KDO35276.1 - 7.8e-66 221.5 62.6 1.8e-37 128.8 22.3 2.8 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KDO35276.1 - 1.4e-36 126.1 0.0 1.2e-18 67.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KDO35276.1 - 1.1e-09 38.0 36.2 7.3e-07 28.6 11.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KDO35276.1 - 7e-08 32.1 0.4 0.0016 18.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO35276.1 - 4.2e-06 26.8 0.1 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KDO35276.1 - 4.6e-06 26.7 2.6 0.44 10.3 0.1 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO35276.1 - 2.7e-05 24.8 1.4 0.031 14.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KDO35276.1 - 2.7e-05 23.8 0.1 0.19 11.3 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KDO35276.1 - 8.1e-05 22.9 0.2 0.37 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KDO35276.1 - 0.00025 20.6 0.0 0.33 10.3 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain PDR_CDR PF06422.12 KDO35276.1 - 0.00048 20.0 10.1 0.002 18.0 0.2 3.9 3 0 0 3 3 3 1 CDR ABC transporter AAA_18 PF13238.6 KDO35276.1 - 0.0007 20.1 0.0 1.9 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KDO35276.1 - 0.00075 19.9 0.1 0.7 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KDO35276.1 - 0.0054 16.9 0.0 4.3 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 KDO35276.1 - 0.0065 16.2 1.4 3 7.7 0.1 2.9 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_30 PF13604.6 KDO35276.1 - 0.0068 16.1 3.9 1.6 8.4 0.6 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KDO35276.1 - 0.0072 16.4 0.2 5.1 7.2 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KDO35276.1 - 0.014 15.7 0.6 5 7.4 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KDO35276.1 - 0.016 15.6 1.9 3.4 8.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KDO35276.1 - 0.034 13.4 0.9 6.7 5.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KDO35276.1 - 0.039 13.9 0.8 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KDO35276.1 - 0.069 13.1 3.1 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KDO35276.1 - 0.084 12.5 3.2 2.4 7.7 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 KDO35276.1 - 0.12 11.7 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 KDO35276.1 - 0.12 12.7 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KDO35276.1 - 0.13 11.6 0.1 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 KDO35276.1 - 0.15 11.1 0.3 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 KDO35276.1 - 0.16 11.7 1.9 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KDO35276.1 - 0.17 11.9 4.8 7.9 6.5 1.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 KDO35276.1 - 0.39 10.6 4.4 0.92 9.4 0.1 2.8 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 KDO35276.1 - 1.2 9.4 5.0 1.7 8.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KDO35276.1 - 2 8.1 3.3 2.9 7.6 0.1 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase eIF2A PF08662.11 KDO35278.1 - 9.1e-54 182.3 6.8 4.9e-48 163.6 1.0 3.5 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KDO35278.1 - 1.5e-07 29.9 0.1 3.8e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KDO35278.1 - 2.7e-05 24.4 0.1 4.9 7.5 0.0 5.8 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KDO35278.1 - 3.2e-05 23.7 0.0 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KDO35278.1 - 0.0002 22.0 0.1 0.68 10.9 0.0 5.0 4 1 1 5 5 5 1 WD domain, G-beta repeat Zein-binding PF04576.15 KDO35278.1 - 0.1 12.9 2.3 0.22 11.8 2.3 1.6 1 0 0 1 1 1 0 Zein-binding Pyrophosphatase PF00719.19 KDO35279.1 - 8.1e-50 168.8 0.1 9.7e-50 168.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase WD40 PF00400.32 KDO35280.1 - 2.1e-28 97.9 28.6 0.00014 22.5 0.0 10.4 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35280.1 - 1.5e-18 66.9 0.4 2.5e-05 24.5 0.0 6.3 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO35280.1 - 6.3e-06 25.7 0.0 5.5 6.2 0.0 4.7 3 1 2 5 5 5 3 WD40-like domain PQQ_2 PF13360.6 KDO35280.1 - 0.0089 15.6 1.6 0.18 11.3 0.2 3.1 2 2 0 3 3 3 1 PQQ-like domain eIF2A PF08662.11 KDO35280.1 - 0.01 15.7 0.0 0.33 10.8 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KDO35280.1 - 0.014 15.9 13.5 6.7 7.3 0.1 6.1 7 0 0 7 7 7 0 PQQ-like domain Nup160 PF11715.8 KDO35280.1 - 0.046 12.4 0.2 0.47 9.0 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KDO35280.1 - 0.17 10.4 0.1 13 4.2 0.0 3.0 4 1 1 5 5 5 0 Cytochrome D1 heme domain RF3_C PF16658.5 KDO35281.1 - 0.0051 16.6 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain B12D PF06522.11 KDO35282.1 - 4.3e-13 48.9 0.0 6.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Pkinase PF00069.25 KDO35283.1 - 2.1e-33 115.8 0.0 4.2e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35283.1 - 1.6e-19 70.2 0.0 2.5e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO35283.1 - 7.5e-11 41.9 0.0 3.2e-10 39.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KDO35283.1 - 0.029 13.7 0.1 0.061 12.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPT PF03151.16 KDO35284.1 - 4e-30 105.2 23.5 4.9e-30 104.9 23.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KDO35284.1 - 4.1e-07 29.5 22.6 5.5e-07 29.1 22.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KDO35284.1 - 4.5e-05 23.6 17.1 4.5e-05 23.6 17.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KDO35284.1 - 0.00019 20.8 25.0 0.0006 19.1 23.3 2.4 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport SAM_2 PF07647.17 KDO35285.1 - 1.6e-12 47.4 0.2 2.6e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KDO35285.1 - 3.2e-11 43.5 0.2 4.6e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SLBP_RNA_bind PF15247.6 KDO35285.1 - 0.0058 16.7 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Peptidase_C97 PF05903.14 KDO35286.1 - 2.6e-44 150.7 0.0 3.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KDO35286.1 - 9.1e-05 21.8 0.8 0.00017 20.9 0.8 1.4 1 0 0 1 1 1 1 PUL domain DRIM PF07539.12 KDO35286.1 - 0.023 13.0 0.2 0.039 12.2 0.2 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis LRAT PF04970.13 KDO35286.1 - 0.055 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF3348 PF11828.8 KDO35286.1 - 0.059 13.0 0.9 0.23 11.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) HSF_DNA-bind PF00447.17 KDO35287.1 - 4.4e-22 78.5 0.1 5.9e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding CPSase_L_D2 PF02786.17 KDO35288.1 - 3e-74 249.1 0.3 5.7e-74 248.2 0.3 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KDO35288.1 - 3.2e-68 229.4 0.0 5.3e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KDO35288.1 - 5e-39 133.3 0.2 2.9e-38 130.8 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KDO35288.1 - 2.5e-30 104.8 0.0 1e-29 102.8 0.0 2.2 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KDO35288.1 - 6.5e-27 94.7 0.0 1.3e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KDO35288.1 - 5.8e-17 61.3 5.1 1.5e-16 60.0 5.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KDO35288.1 - 3.9e-11 42.9 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KDO35288.1 - 8.5e-11 41.5 1.0 6.5e-05 22.7 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KDO35288.1 - 1.2e-06 28.2 0.2 3.4e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KDO35288.1 - 1.7e-06 28.1 0.0 4.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KDO35288.1 - 7.2e-05 22.1 1.2 0.076 12.2 0.1 2.9 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 KDO35288.1 - 0.00014 21.5 0.1 0.00029 20.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KDO35288.1 - 0.00016 22.3 0.3 0.79 10.4 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein NQRA PF05896.11 KDO35288.1 - 0.0031 17.0 0.7 0.0052 16.3 0.7 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 KDO35288.1 - 0.0082 16.1 0.8 0.024 14.6 0.8 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 KDO35288.1 - 0.0087 15.3 0.0 0.07 12.4 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 KDO35288.1 - 0.0091 15.7 0.6 0.022 14.5 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GCV_H PF01597.19 KDO35288.1 - 0.028 14.3 1.3 0.11 12.4 1.3 2.1 1 0 0 1 1 1 0 Glycine cleavage H-protein HSF_DNA-bind PF00447.17 KDO35289.1 - 1.3e-24 86.7 0.9 2.1e-24 86.0 0.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding TMEM65 PF10507.9 KDO35290.1 - 6.7e-35 119.3 2.5 1.2e-34 118.6 2.5 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 KDO35290.1 - 0.023 14.2 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KDO35290.1 - 0.041 14.3 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KDO35290.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KDO35290.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 EF hand Myosin_head PF00063.21 KDO35291.1 - 1.8e-214 713.9 2.8 2.8e-214 713.2 2.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KDO35291.1 - 1.5e-32 112.8 6.2 2.8e-32 111.9 6.2 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 KDO35291.1 - 5.7e-05 23.4 1.0 0.017 15.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KDO35291.1 - 0.0013 19.1 0.6 0.0057 17.0 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KDO35291.1 - 0.0061 16.9 0.5 0.044 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KDO35291.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KDO35291.1 - 0.23 11.3 3.3 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PDEase_I PF00233.19 KDO35292.1 - 4.1e-49 167.5 1.4 4.9e-49 167.2 1.4 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2273 PF10031.9 KDO35293.1 - 2.9 8.0 11.7 0.19 11.7 4.8 2.2 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) TPR_2 PF07719.17 KDO35294.1 - 4.9e-16 57.5 3.2 0.00017 21.5 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KDO35294.1 - 4.1e-13 49.6 0.3 2e-07 31.4 0.1 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO35294.1 - 6.3e-13 47.9 3.1 0.00016 21.4 0.2 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KDO35294.1 - 1.7e-12 47.0 4.4 0.00085 19.9 0.1 4.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KDO35294.1 - 4.6e-12 45.4 0.9 0.0063 16.8 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KDO35294.1 - 3.3e-11 43.6 7.8 3e-05 24.6 0.2 3.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KDO35294.1 - 8e-11 41.4 1.6 0.0011 18.6 0.1 4.2 2 2 2 4 4 4 2 TPR repeat TPR_12 PF13424.6 KDO35294.1 - 4.6e-10 39.7 2.9 6.7e-05 23.1 0.6 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KDO35294.1 - 1.5e-09 37.2 4.6 0.23 11.6 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO35294.1 - 3.8e-07 29.8 1.6 1.5 9.3 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KDO35294.1 - 7.2e-07 29.3 4.9 0.0072 16.4 0.1 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KDO35294.1 - 2.5e-06 27.2 8.3 0.19 11.6 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KDO35294.1 - 4.1e-06 26.9 0.0 9.1 7.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KDO35294.1 - 2e-05 24.8 3.0 0.17 12.3 0.2 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat Coatomer_E PF04733.14 KDO35294.1 - 0.0002 20.9 0.0 0.03 13.7 0.0 2.3 2 1 0 2 2 2 1 Coatomer epsilon subunit DUF4919 PF16266.5 KDO35294.1 - 0.00021 21.3 0.1 0.16 11.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4919) TPR_MalT PF17874.1 KDO35294.1 - 0.001 18.5 1.5 0.055 12.8 0.0 2.6 1 1 2 3 3 3 1 MalT-like TPR region BTAD PF03704.17 KDO35294.1 - 0.0043 17.5 1.0 0.11 13.0 0.4 2.6 1 1 2 3 3 3 2 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 KDO35294.1 - 0.0055 16.7 0.5 3 7.7 0.1 2.1 1 1 0 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 KDO35294.1 - 0.02 15.1 0.4 0.1 12.8 0.3 2.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TAF1_subA PF14929.6 KDO35294.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_15 PF13429.6 KDO35294.1 - 0.04 13.1 0.8 4.4 6.4 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 KDO35294.1 - 0.11 12.6 0.2 1.1 9.4 0.0 2.4 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) SMBP PF16785.5 KDO35294.1 - 0.17 12.1 0.8 0.78 10.0 0.1 2.1 1 1 0 1 1 1 0 Small metal-binding protein TPR_6 PF13174.6 KDO35294.1 - 0.29 11.9 5.9 14 6.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat B12D PF06522.11 KDO35295.1 - 6.8e-15 54.6 0.0 8.9e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 KDO35296.1 - 3.3e-12 46.0 0.0 4.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3987 PF13148.6 KDO35297.1 - 0.024 13.7 0.4 0.032 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) V-SNARE PF05008.15 KDO35297.1 - 0.028 14.8 2.1 0.063 13.7 0.1 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4201 PF13870.6 KDO35297.1 - 0.078 12.7 0.9 0.1 12.3 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc24 PF08286.11 KDO35297.1 - 0.082 13.2 0.4 0.12 12.6 0.4 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 KDO35297.1 - 0.12 12.6 4.5 0.25 11.6 4.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain GIT_CC PF16559.5 KDO35297.1 - 0.38 10.7 3.5 0.62 10.0 3.5 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor GreA_GreB_N PF03449.15 KDO35297.1 - 0.75 10.0 3.0 7.6 6.8 0.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal EF-hand_1 PF00036.32 KDO35298.1 - 0.042 13.4 1.2 0.18 11.4 0.0 2.7 3 0 0 3 3 3 0 EF hand Jnk-SapK_ap_N PF09744.9 KDO35298.1 - 0.064 13.5 10.8 0.045 14.0 1.1 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NOA36 PF06524.12 KDO35298.1 - 0.22 10.8 5.7 0.11 11.8 3.6 1.6 2 0 0 2 2 2 0 NOA36 protein DHR10 PF18595.1 KDO35298.1 - 1.3 9.1 12.3 0.13 12.4 1.4 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TSC22 PF01166.18 KDO35298.1 - 4.4 7.7 6.3 20 5.6 0.3 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF1336 PF07059.12 KDO35299.1 - 6.4e-56 190.0 0.0 1.4e-55 188.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 KDO35299.1 - 2.3e-19 69.6 0.5 3.7e-19 69.0 0.5 1.3 1 0 0 1 1 1 1 START domain PH PF00169.29 KDO35299.1 - 2.2e-05 24.9 0.9 5.8e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 PH domain Kelch_1 PF01344.25 KDO35300.1 - 7.4e-40 134.3 18.3 8.8e-11 41.2 0.0 7.1 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 KDO35300.1 - 6.2e-33 112.0 8.0 1.5e-05 25.1 0.0 6.6 2 2 4 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KDO35300.1 - 7.5e-19 67.5 5.2 0.049 13.9 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KDO35300.1 - 1.8e-15 56.6 3.2 0.0016 18.4 0.1 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KDO35300.1 - 6.7e-10 38.5 7.1 0.025 14.6 0.2 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KDO35300.1 - 0.00052 19.9 6.1 2.9 8.0 0.0 4.7 5 0 0 5 5 5 2 Kelch motif zf-C2H2 PF00096.26 KDO35300.1 - 0.087 13.3 0.2 0.26 11.8 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type STIMATE PF12400.8 KDO35301.1 - 2.6e-34 118.4 6.9 2.6e-34 118.4 6.9 1.5 2 0 0 2 2 2 1 STIMATE family Oxidored_FMN PF00724.20 KDO35302.1 - 1e-84 284.8 0.0 1.2e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KDO35302.1 - 0.14 11.6 0.0 8.7 5.7 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel ANAPC4_WD40 PF12894.7 KDO35303.1 - 0.054 13.8 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain BT1 PF03092.16 KDO35304.1 - 1.5e-10 40.0 2.4 1.5e-10 40.0 2.4 3.1 3 0 0 3 3 3 3 BT1 family TIP120 PF08623.10 KDO35305.1 - 0.11 12.3 0.6 0.18 11.6 0.6 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) BTB PF00651.31 KDO35306.1 - 2.1e-20 73.0 0.6 1.5e-17 63.8 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain Rad60-SLD PF11976.8 KDO35306.1 - 0.0034 17.2 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HECW1_helix PF18436.1 KDO35306.1 - 0.089 12.9 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 BACK PF07707.15 KDO35306.1 - 0.18 11.9 4.5 0.58 10.3 0.2 3.2 3 1 1 4 4 4 0 BTB And C-terminal Kelch Acyltransferase PF01553.21 KDO35307.1 - 8.4e-16 57.8 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KDO35307.1 - 2.1e-12 46.9 0.0 3.7e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Smim3 PF17307.2 KDO35307.1 - 2.1 7.9 5.4 0.28 10.7 0.9 1.8 2 0 0 2 2 2 0 Small integral membrane protein 3 Ion_trans PF00520.31 KDO35308.1 - 2.3e-05 23.7 13.5 0.0014 18.0 13.5 3.2 1 1 1 2 2 2 1 Ion transport protein DUF2973 PF11189.8 KDO35308.1 - 0.69 10.0 2.7 0.62 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) RIH_assoc PF08454.11 KDO35309.1 - 1.2e-12 47.6 1.2 2.8e-12 46.4 1.2 1.6 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 KDO35312.1 - 7e-06 25.4 0.1 1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Ion transport protein DUF2973 PF11189.8 KDO35312.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) PQ-loop PF04193.14 KDO35313.1 - 2.1e-35 120.3 19.9 3.9e-18 65.0 7.3 2.7 3 0 0 3 3 3 2 PQ loop repeat PQ-loop PF04193.14 KDO35314.1 - 7e-37 125.0 14.8 4.4e-18 64.8 7.3 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF3852 PF12963.7 KDO35314.1 - 2.1 8.7 6.8 0.91 9.9 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3852) PQ-loop PF04193.14 KDO35315.1 - 2.7e-32 110.3 17.7 2.9e-18 65.4 6.2 3.1 4 0 0 4 4 4 2 PQ loop repeat DUF5090 PF17009.5 KDO35315.1 - 1.6 8.7 6.6 0.88 9.5 1.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) Ank_2 PF12796.7 KDO35316.1 - 8.3e-06 26.3 0.0 0.023 15.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO35316.1 - 0.00057 20.1 2.0 2.1 9.2 0.2 4.1 4 1 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KDO35316.1 - 0.1 13.2 0.1 0.42 11.2 0.1 2.1 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Leucyl-specific PF14795.6 KDO35317.1 - 0.048 13.7 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain YL1 PF05764.13 KDO35318.1 - 0.0072 16.5 3.2 0.0095 16.1 3.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein RRN3 PF05327.11 KDO35318.1 - 0.0077 14.8 2.0 0.01 14.4 2.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF4825 PF16107.5 KDO35318.1 - 0.055 13.6 0.7 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4825) DUF4611 PF15387.6 KDO35318.1 - 0.2 11.9 7.0 0.48 10.7 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GOLD_2 PF13897.6 KDO35318.1 - 0.29 11.6 2.0 0.51 10.8 2.0 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Pkinase PF00069.25 KDO35319.1 - 3.2e-49 167.7 0.0 4.9e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35319.1 - 4.7e-16 58.9 0.0 9.7e-16 57.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase eIF3g PF12353.8 KDO35319.1 - 1.9e-08 34.8 52.5 0.0023 18.3 0.2 7.7 2 1 6 8 8 8 6 Eukaryotic translation initiation factor 3 subunit G DUF1752 PF08550.10 KDO35319.1 - 1.2e-07 31.4 1.8 2.8e-07 30.3 1.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PH PF00169.29 KDO35319.1 - 1.4e-06 28.7 0.0 3.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 PH domain LRR_8 PF13855.6 KDO35320.1 - 1.2e-08 34.5 0.0 2.1e-05 24.2 0.0 4.0 3 1 1 4 4 4 2 Leucine rich repeat EutH PF04346.12 KDO35320.1 - 0.22 10.7 6.1 1.1 8.3 1.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation protein, EutH Ank_5 PF13857.6 KDO35321.1 - 0.00048 20.4 0.4 0.0073 16.6 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO35321.1 - 0.002 18.7 0.0 0.12 12.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO35321.1 - 0.019 15.5 1.2 33 5.5 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 KDO35321.1 - 1.2 9.7 0.1 1.2 9.7 0.1 3.0 4 0 0 4 4 4 0 Ankyrin repeat ELO PF01151.18 KDO35322.1 - 4.7e-44 150.8 17.2 5.4e-44 150.6 17.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PfkB PF00294.24 KDO35323.1 - 5.2e-51 173.7 0.1 6e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Dehydrin PF00257.19 KDO35324.1 - 0.0012 19.5 1.9 0.0019 18.8 1.9 1.3 1 0 0 1 1 1 1 Dehydrin CcmD PF04995.14 KDO35324.1 - 0.071 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3290 PF11694.8 KDO35324.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) TSC22 PF01166.18 KDO35325.1 - 0.086 13.2 0.4 11 6.4 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CcmD PF04995.14 KDO35326.1 - 0.065 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PepSY_2 PF13670.6 KDO35327.1 - 0.14 12.2 0.6 0.16 12.0 0.6 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain GRP PF07172.11 KDO35329.1 - 1.8 9.3 25.7 3.6 8.3 25.7 1.6 1 1 0 1 1 1 0 Glycine rich protein family EthD PF07110.11 KDO35330.1 - 0.26 12.4 3.1 16 6.7 0.3 2.3 1 1 0 2 2 2 0 EthD domain DUF3796 PF12676.7 KDO35330.1 - 3.2 8.2 5.2 16 6.0 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) WD40 PF00400.32 KDO35331.1 - 2e-12 47.4 5.0 0.0076 17.1 0.3 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat MPS2 PF17060.5 KDO35331.1 - 7.1e-05 22.2 12.9 7.1e-05 22.2 12.9 3.0 1 1 2 3 3 3 1 Monopolar spindle protein 2 KASH_CCD PF14662.6 KDO35331.1 - 0.0029 17.5 22.2 0.0029 17.5 22.2 5.4 1 1 1 4 4 4 1 Coiled-coil region of CCDC155 or KASH HSP70 PF00012.20 KDO35333.1 - 5.8e-86 289.0 0.0 8.8e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO35333.1 - 4.5e-07 29.0 2.8 9.5e-07 27.9 2.8 1.5 1 0 0 1 1 1 1 MreB/Mbl protein GP46 PF07409.12 KDO35333.1 - 0.073 12.8 0.4 0.26 11.1 0.4 2.0 1 0 0 1 1 1 0 Phage protein GP46 Peptidase_C25_C PF03785.14 KDO35333.1 - 0.14 12.0 2.5 0.76 9.7 0.5 3.1 4 0 0 4 4 4 0 Peptidase family C25, C terminal ig-like domain HSP70 PF00012.20 KDO35334.1 - 3.3e-94 316.2 0.0 3.8e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KDO35334.1 - 4.8e-06 25.6 3.7 7.9e-06 24.9 0.8 2.4 2 1 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 KDO35334.1 - 0.0082 14.8 0.7 0.026 13.1 0.1 2.0 3 0 0 3 3 3 1 Actin BcrAD_BadFG PF01869.20 KDO35334.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family PilM_2 PF11104.8 KDO35334.1 - 0.054 12.5 2.2 3.9 6.4 0.0 2.6 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; FtsA PF14450.6 KDO35334.1 - 0.2 12.1 1.6 2.9 8.4 0.1 2.8 2 1 0 2 2 2 0 Cell division protein FtsA 2_5_RNA_ligase2 PF13563.6 KDO35335.1 - 6.8e-21 74.8 0.2 8.1e-21 74.5 0.2 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KDO35335.1 - 0.0034 17.6 0.2 0.056 13.7 0.0 2.2 2 0 0 2 2 2 1 LigT like Phosphoesterase SWI2_SNF2 PF18766.1 KDO35336.1 - 2.3e-26 92.8 1.0 3.9e-26 92.1 1.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 KDO35336.1 - 5e-21 75.4 0.2 7.7e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KDO35336.1 - 3.2e-12 46.6 1.3 5.4e-12 45.8 1.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase WW PF00397.26 KDO35336.1 - 4e-08 33.2 0.3 8.2e-08 32.2 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF2075 PF09848.9 KDO35336.1 - 0.008 15.5 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KDO35336.1 - 0.057 12.8 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KDO35336.1 - 0.11 13.0 0.1 0.28 11.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KDO35336.1 - 0.11 12.7 0.4 0.51 10.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain DENN PF02141.21 KDO35337.1 - 1.3e-23 84.0 2.5 1.3e-23 84.0 2.5 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KDO35337.1 - 1.6e-05 25.5 0.0 5.7e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Avl9 PF09794.9 KDO35337.1 - 0.17 10.6 0.1 0.3 9.7 0.1 1.3 1 0 0 1 1 1 0 Transport protein Avl9 zf-HIT PF04438.16 KDO35338.1 - 4.2e-09 36.1 13.0 7.2e-09 35.4 13.0 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 KDO35338.1 - 0.0015 18.3 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dam1 PF08653.10 KDO35338.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 TPR_20 PF14561.6 KDO35338.1 - 0.22 11.9 3.1 0.41 11.0 3.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.18 KDO35338.1 - 1 9.5 12.4 1.7 8.8 12.4 1.4 1 0 0 1 1 1 0 MYND finger RNase_Zc3h12a PF11977.8 KDO35339.1 - 3.5e-16 59.4 0.0 6.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 KDO35339.1 - 0.00024 20.7 0.1 0.00049 19.7 0.1 1.4 1 0 0 1 1 1 1 Protein-only RNase P NOA36 PF06524.12 KDO35340.1 - 7.8 5.7 9.2 10 5.3 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.19 KDO35341.1 - 0.083 10.8 0.1 0.088 10.7 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNARE_assoc PF09335.11 KDO35342.1 - 2.6e-05 24.7 1.0 6.5e-05 23.4 1.0 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein ANAPC4_WD40 PF12894.7 KDO35345.1 - 1.3e-18 67.1 0.2 0.0026 18.0 0.1 8.8 2 2 8 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KDO35345.1 - 8.8e-13 48.5 20.4 0.046 14.6 0.0 10.0 11 0 0 11 11 11 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KDO35345.1 - 0.0018 17.3 0.1 2.1 7.2 0.0 3.8 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 KDO35345.1 - 0.0018 16.9 0.0 1.2 7.7 0.0 2.7 2 1 1 3 3 3 2 beta-propeller of ELYS nucleoporin DUF5570 PF17731.1 KDO35345.1 - 0.0028 17.7 0.3 0.0067 16.5 0.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5570) PQQ_3 PF13570.6 KDO35345.1 - 0.0029 18.1 0.4 12 6.6 0.1 5.0 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 KDO35345.1 - 0.0043 16.7 1.0 0.072 12.7 0.1 2.9 2 2 0 2 2 2 1 PQQ-like domain Ribonuclease_3 PF00636.26 KDO35346.1 - 1e-30 106.5 0.0 1.3e-16 61.1 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KDO35346.1 - 5.5e-16 58.5 1.8 4.3e-15 55.6 0.1 3.0 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KDO35346.1 - 3.1e-15 56.5 0.0 3.3e-08 33.7 0.0 3.6 2 1 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.29 KDO35346.1 - 0.00018 21.3 0.2 0.00035 20.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KDO35346.1 - 0.0046 17.4 0.0 0.019 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KDO35346.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KDO35346.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KDO35346.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rpr2 PF04032.16 KDO35347.1 - 2.9e-08 33.9 0.1 4.4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Utp12 PF04003.12 KDO35348.1 - 3.4 8.0 8.6 34 4.8 0.3 3.8 2 1 1 3 3 3 0 Dip2/Utp12 Family Cullin PF00888.22 KDO35349.1 - 1.2e-25 90.2 0.0 1.7e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KDO35349.1 - 7.4e-19 68.0 0.0 2.4e-18 66.4 0.0 2.0 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 PPP4R2 PF09184.11 KDO35350.1 - 8.3e-14 51.9 0.1 8.8e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 PPP4R2 Strumpellin PF10266.9 KDO35350.1 - 0.008 13.9 0.0 0.008 13.9 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DUF2397 PF09660.10 KDO35351.1 - 0.012 14.5 1.9 0.022 13.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Hamartin PF04388.12 KDO35351.1 - 0.63 8.6 5.4 0.61 8.7 5.4 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 KDO35351.1 - 2.3 6.8 3.6 2.1 6.9 3.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PQ-loop PF04193.14 KDO35352.1 - 4.3e-29 100.1 8.9 2.7e-14 52.7 5.3 2.6 2 0 0 2 2 2 2 PQ loop repeat ABC_tran PF00005.27 KDO35354.1 - 4e-34 118.1 0.1 1.1e-33 116.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KDO35354.1 - 4.7e-22 78.9 12.4 9.4e-21 74.7 12.4 2.2 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO35354.1 - 9.6e-07 28.5 0.0 3.6e-05 23.3 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KDO35354.1 - 0.0011 19.3 0.3 0.014 15.6 0.1 2.6 2 1 0 2 2 1 1 AAA domain DUF87 PF01935.17 KDO35354.1 - 0.009 16.1 0.1 0.029 14.5 0.1 1.9 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 KDO35354.1 - 0.022 13.7 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_21 PF13304.6 KDO35354.1 - 0.025 14.4 0.1 1.3 8.8 0.1 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KDO35354.1 - 0.027 14.4 0.0 0.09 12.7 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 KDO35354.1 - 0.033 14.4 0.2 0.43 10.8 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KDO35354.1 - 0.033 14.3 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO35354.1 - 0.075 13.4 0.8 0.37 11.1 0.8 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KDO35354.1 - 0.095 12.9 1.9 6.2 7.0 0.3 3.1 1 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KDO35354.1 - 0.11 12.2 0.3 0.38 10.5 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ECSCR PF15820.5 KDO35354.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Ank_2 PF12796.7 KDO35355.1 - 3.9e-33 113.9 1.5 4.4e-13 49.6 0.2 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO35355.1 - 1.9e-23 82.5 4.0 1.6e-05 25.4 0.2 6.2 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO35355.1 - 6.5e-21 72.2 11.9 0.025 15.1 0.1 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KDO35355.1 - 1.2e-17 63.8 16.5 5.9e-06 26.4 1.2 6.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KDO35355.1 - 1.4e-17 63.3 19.3 0.027 14.9 0.4 8.0 7 1 1 8 8 8 5 Ankyrin repeat Patched PF02460.18 KDO35356.1 - 4.4e-59 200.4 16.9 2.5e-46 158.2 2.4 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KDO35356.1 - 7.7e-37 126.5 5.5 7.7e-37 126.5 5.5 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 KDO35356.1 - 7.5e-12 45.3 7.1 7.5e-12 45.3 7.1 1.8 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus PQ-loop PF04193.14 KDO35360.1 - 2.6e-18 65.5 5.2 4.1e-10 39.3 0.4 3.2 3 0 0 3 3 3 2 PQ loop repeat ABC_tran PF00005.27 KDO35361.1 - 2.4e-45 154.4 0.3 7.3e-23 81.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KDO35361.1 - 8.5e-20 70.6 5.5 8.5e-20 70.6 5.5 2.5 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KDO35361.1 - 2.5e-19 70.2 5.8 0.00018 21.4 0.0 4.7 3 2 2 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO35361.1 - 8.3e-12 45.0 2.0 0.0019 17.7 0.0 4.2 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KDO35361.1 - 4.2e-06 26.6 0.0 0.018 14.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KDO35361.1 - 1.1e-05 25.1 1.7 0.035 13.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KDO35361.1 - 2e-05 24.6 0.1 0.017 15.2 0.2 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KDO35361.1 - 7.8e-05 23.1 0.0 0.35 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO35361.1 - 0.00036 20.5 2.4 0.21 11.5 0.1 2.8 3 0 0 3 3 2 2 RsgA GTPase MeaB PF03308.16 KDO35361.1 - 0.00079 18.5 0.1 0.046 12.7 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KDO35361.1 - 0.00086 19.1 3.1 0.24 11.1 0.0 3.6 4 1 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 KDO35361.1 - 0.001 19.6 0.9 0.052 14.0 0.1 4.6 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.6 KDO35361.1 - 0.0014 19.0 2.9 0.46 10.8 0.0 3.8 3 2 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KDO35361.1 - 0.0015 18.8 0.7 4.2 7.7 0.0 3.5 4 0 0 4 4 2 1 AAA domain NACHT PF05729.12 KDO35361.1 - 0.0023 17.9 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 KDO35361.1 - 0.0065 15.7 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 KDO35361.1 - 0.0081 15.8 0.3 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KDO35361.1 - 0.011 15.7 0.0 7 6.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KDO35361.1 - 0.013 15.7 1.7 1.6 8.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KDO35361.1 - 0.014 15.2 3.0 3.8 7.2 0.2 3.4 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.14 KDO35361.1 - 0.014 14.7 0.1 6.7 5.9 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain AAA_18 PF13238.6 KDO35361.1 - 0.033 14.7 6.5 1.7 9.2 0.5 4.0 4 1 0 4 4 3 0 AAA domain DUF87 PF01935.17 KDO35361.1 - 0.042 13.9 0.1 0.042 13.9 0.1 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain SbcCD_C PF13558.6 KDO35361.1 - 0.049 13.9 0.1 5.2 7.4 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KDO35361.1 - 0.051 13.7 7.5 1.5 9.0 0.0 3.5 4 1 0 4 4 4 0 AAA domain Thymidylate_kin PF02223.17 KDO35361.1 - 0.053 13.2 1.3 1.3 8.6 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.15 KDO35361.1 - 0.069 13.1 0.2 3.7 7.4 0.1 2.8 2 0 0 2 2 2 0 NTPase MobB PF03205.14 KDO35361.1 - 0.069 13.0 0.3 10 6.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Phage_int_SAM_2 PF12834.7 KDO35361.1 - 0.07 13.8 0.7 12 6.7 0.2 2.7 2 0 0 2 2 2 0 Phage integrase, N-terminal Roc PF08477.13 KDO35361.1 - 0.077 13.2 0.1 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KDO35361.1 - 0.1 12.3 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KDO35361.1 - 0.12 12.9 0.1 33 4.9 0.0 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 KDO35361.1 - 0.12 11.8 1.8 7.1 6.0 0.0 3.2 3 1 0 3 3 3 0 ADP-ribosylation factor family AAA_17 PF13207.6 KDO35361.1 - 0.25 11.8 2.2 28 5.1 0.1 3.6 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KDO35361.1 - 0.85 9.6 0.0 0.85 9.6 0.0 3.3 4 0 0 4 4 4 0 Dynamin family AAA_13 PF13166.6 KDO35361.1 - 2.6 6.6 13.6 0.55 8.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 KDO35361.1 - 3.1 7.5 6.3 23 4.6 0.1 3.6 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein YecM PF06185.12 KDO35363.1 - 3.3e-23 82.3 0.0 9.4e-22 77.5 0.0 2.0 1 1 0 1 1 1 1 YecM protein DUF3017 PF11222.8 KDO35363.1 - 0.34 11.2 1.9 0.71 10.2 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) Arm PF00514.23 KDO35365.1 - 3.8e-16 58.5 50.5 0.0003 20.7 0.3 15.7 18 1 0 18 18 18 6 Armadillo/beta-catenin-like repeat KAP PF05804.12 KDO35365.1 - 2.9e-10 39.0 17.7 9.2e-05 20.8 0.6 4.7 3 3 1 4 4 4 3 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 KDO35365.1 - 0.00013 22.2 7.6 3.9 7.9 0.0 6.6 4 3 3 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KDO35365.1 - 0.00015 21.8 10.4 0.0017 18.4 0.2 4.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KDO35365.1 - 0.0012 18.9 5.1 3.8 8.0 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KDO35365.1 - 0.014 15.9 21.1 8.5 7.0 0.4 7.6 8 0 0 8 8 8 0 HEAT-like repeat Arm_2 PF04826.13 KDO35365.1 - 0.043 13.3 16.8 3.7 6.9 0.2 5.8 4 2 2 6 6 6 0 Armadillo-like HutD PF05962.11 KDO35365.1 - 0.12 12.3 0.0 0.43 10.5 0.0 1.9 1 0 0 1 1 1 0 HutD LRR_8 PF13855.6 KDO35366.1 - 1.4e-26 92.0 23.7 1.7e-09 37.3 2.0 4.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KDO35366.1 - 3.4e-25 87.7 39.5 1.2e-07 31.9 5.8 4.9 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KDO35366.1 - 9.8e-11 41.5 5.1 5.6e-05 22.7 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KDO35366.1 - 3.4e-07 29.9 12.6 2.5 9.0 0.0 7.6 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KDO35366.1 - 1.9e-05 24.3 14.8 9.8 6.5 0.6 6.5 6 0 0 6 6 6 4 Leucine Rich repeat LRR_5 PF13306.6 KDO35366.1 - 0.00014 21.9 0.2 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 KDO35366.1 - 0.14 12.9 4.7 9.3 7.1 0.3 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat DUF5566 PF17721.1 KDO35366.1 - 0.21 11.9 0.1 0.28 11.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5566) MFS_1 PF07690.16 KDO35367.1 - 4.4e-26 91.7 41.4 5.6e-14 51.8 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KDO35367.1 - 1e-06 28.4 5.4 1e-06 28.4 5.4 2.4 2 1 0 2 2 2 1 Nodulin-like Sugar_tr PF00083.24 KDO35367.1 - 0.021 13.7 25.4 0.034 13.0 9.2 2.1 2 0 0 2 2 2 0 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 KDO35367.1 - 3.3 8.1 7.8 0.53 10.6 0.7 3.3 4 1 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V LRR_6 PF13516.6 KDO35368.1 - 5.3e-19 66.6 28.8 0.0018 18.1 0.1 8.6 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 KDO35368.1 - 4.8e-06 26.8 8.1 0.015 15.8 0.0 5.2 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO35368.1 - 0.00068 19.3 13.4 0.031 14.1 0.0 5.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KDO35368.1 - 0.0074 16.7 7.7 73 4.5 0.0 6.6 7 1 1 8 8 8 0 Leucine Rich Repeat ATP-synt_ab PF00006.25 KDO35369.1 - 4.3e-49 167.1 0.4 6.9e-24 84.7 0.0 2.2 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KDO35369.1 - 1.3e-22 80.0 1.6 3e-22 78.9 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 KDO35369.1 - 0.0091 16.3 0.8 0.099 13.0 0.3 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KDO35369.1 - 0.019 14.9 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab_N PF02874.23 KDO35370.1 - 5.2e-23 81.4 1.6 9.8e-23 80.5 1.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MSA-2c PF12238.8 KDO35371.1 - 0.073 13.1 1.1 0.14 12.1 1.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c RCC1 PF00415.18 KDO35373.1 - 7.1e-67 221.9 25.8 3.3e-14 53.3 0.2 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KDO35373.1 - 1.1e-29 101.6 50.1 2.9e-07 30.1 0.2 8.4 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Filamin PF00630.19 KDO35373.1 - 1.5e-09 38.6 0.0 1.5e-08 35.4 0.0 2.5 2 1 0 2 2 2 1 Filamin/ABP280 repeat TPR_2 PF07719.17 KDO35373.1 - 0.0013 18.7 4.4 6.6 7.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KDO35373.1 - 0.01 16.3 5.4 0.026 15.0 1.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KDO35373.1 - 0.19 11.6 1.4 32 4.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KDO35373.1 - 4.3 7.1 4.7 50 3.7 0.1 3.3 3 0 0 3 3 3 0 TPR repeat Kinesin PF00225.23 KDO35374.1 - 7.8e-105 350.5 0.2 1e-104 350.1 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO35374.1 - 1.9e-19 70.1 0.0 5.8e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Herpes_BLRF2 PF05812.12 KDO35374.1 - 0.025 14.7 3.2 0.2 11.8 0.2 3.0 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein DUF4407 PF14362.6 KDO35374.1 - 0.17 11.2 9.2 0.042 13.2 5.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KDO35374.1 - 0.17 12.4 11.9 0.65 10.5 0.7 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region TssO PF17561.2 KDO35374.1 - 0.18 11.9 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO THOC7 PF05615.13 KDO35374.1 - 0.32 11.3 12.7 2.2 8.6 3.2 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4200 PF13863.6 KDO35374.1 - 0.35 11.3 10.4 2.2 8.7 0.3 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) HAUS-augmin3 PF14932.6 KDO35374.1 - 0.5 9.9 11.3 0.46 10.0 4.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 KDO35374.1 - 0.63 9.4 8.7 1.3 8.4 1.9 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.8 KDO35374.1 - 1 9.5 3.0 1.6 8.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.22 KDO35374.1 - 3.2 8.0 8.2 13 6.1 0.4 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 KDO35374.1 - 4.1 7.3 14.5 1.2 9.0 3.1 3.1 3 1 0 3 3 3 0 Septum formation initiator YabA PF06156.13 KDO35374.1 - 5.6 7.7 9.5 1.3 9.7 0.7 3.7 3 1 0 4 4 3 0 Initiation control protein YabA Carb_kinase PF01256.17 KDO35375.1 - 1.6e-51 175.2 0.2 1.8e-51 175.0 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate kinase TMEM154 PF15102.6 KDO35376.1 - 0.00028 20.8 0.0 0.00091 19.1 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family Barwin PF00967.17 KDO35376.1 - 0.013 15.3 0.5 0.023 14.5 0.5 1.4 1 0 0 1 1 1 0 Barwin family DAP10 PF07213.11 KDO35376.1 - 0.078 13.0 0.3 0.078 13.0 0.3 2.4 2 1 0 2 2 2 0 DAP10 membrane protein Voltage_CLC PF00654.20 KDO35377.1 - 1.5e-69 234.9 22.7 2.2e-69 234.4 22.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KDO35377.1 - 9.1e-08 32.4 0.2 0.0012 19.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain Phage_GP20 PF06810.11 KDO35378.1 - 0.0097 15.7 2.3 0.019 14.8 2.3 1.4 1 0 0 1 1 1 1 Phage minor structural protein GP20 PRKG1_interact PF15898.5 KDO35378.1 - 0.016 16.1 1.1 0.042 14.8 1.1 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain PTS_IIB PF02302.17 KDO35378.1 - 0.018 15.8 1.3 8.1 7.2 0.3 3.1 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit BST2 PF16716.5 KDO35378.1 - 0.11 13.1 5.2 0.31 11.7 5.2 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Scaffolding_pro PF11418.8 KDO35378.1 - 0.15 12.6 0.3 5.5 7.6 0.2 2.4 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF724 PF05266.14 KDO35378.1 - 0.6 9.9 1.9 1 9.2 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 KDO35378.1 - 0.97 9.9 4.0 1.2 9.6 2.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 KDO35378.1 - 2.6 6.8 5.4 4.1 6.2 5.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_2 PF07716.15 KDO35378.1 - 2.7 8.1 5.3 52 4.0 0.1 3.6 4 0 0 4 4 4 0 Basic region leucine zipper Glyco_hydro_17 PF00332.18 KDO35379.1 - 0.035 13.7 2.3 0.11 12.1 1.8 2.0 3 0 0 3 3 3 0 Glycosyl hydrolases family 17 PRCC PF10253.9 KDO35379.1 - 0.072 13.9 1.4 0.1 13.3 1.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MHYT PF03707.16 KDO35379.1 - 1.5 9.0 5.4 1.6 9.0 0.4 2.5 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat MSA-2c PF12238.8 KDO35379.1 - 9.4 6.2 12.9 20 5.1 12.9 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c PolyA_pol PF01743.20 KDO35380.1 - 1.5e-28 99.7 0.0 2.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KDO35380.1 - 6.5e-05 22.6 0.0 0.00017 21.2 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KDO35380.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Glyco_hydro_17 PF00332.18 KDO35381.1 - 0.02 14.5 4.7 0.048 13.2 3.5 2.1 3 0 0 3 3 3 0 Glycosyl hydrolases family 17 NdhS PF11623.8 KDO35381.1 - 0.12 12.1 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S Pkinase_Tyr PF07714.17 KDO35383.1 - 7.3e-44 150.0 0.0 1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO35383.1 - 5.8e-41 140.6 0.0 2.3e-30 105.9 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 KDO35383.1 - 0.0057 15.5 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_4 PF12799.7 KDO35383.1 - 0.48 10.9 2.8 0.44 11.0 0.4 1.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) PDCD7 PF16021.5 KDO35385.1 - 2.4e-08 33.4 11.1 7e-08 31.9 0.2 2.5 2 1 0 2 2 2 2 Programmed cell death protein 7 Pkinase PF00069.25 KDO35386.1 - 2.2e-43 148.5 0.0 4e-43 147.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35386.1 - 4.4e-43 147.4 0.0 6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO35386.1 - 0.034 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LapA_dom PF06305.11 KDO35386.1 - 0.045 13.6 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HemY_N PF07219.13 KDO35386.1 - 0.13 12.5 0.0 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 HemY protein N-terminus SKG6 PF08693.10 KDO35386.1 - 0.13 11.7 0.9 0.25 10.8 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 KDO35388.1 - 1.1e-41 142.9 0.0 5.6e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35388.1 - 2.8e-40 138.2 0.0 3.9e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 KDO35388.1 - 1.8e-10 40.9 7.8 0.015 15.7 1.8 4.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO35388.1 - 7.7e-07 28.8 9.9 0.065 13.0 1.2 4.0 1 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KDO35388.1 - 0.21 11.1 0.0 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat Pkinase_fungal PF17667.1 KDO35388.1 - 0.21 10.3 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ABC2_membrane PF01061.24 KDO35389.1 - 2.8e-64 216.4 60.5 2.2e-35 122.0 27.8 2.9 2 1 1 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KDO35389.1 - 7.5e-36 123.7 0.0 3.5e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO35389.1 - 1.3e-12 48.1 0.1 0.015 15.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KDO35389.1 - 4.1e-10 40.3 0.4 0.00067 20.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KDO35389.1 - 2.5e-08 34.0 0.8 0.0015 18.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KDO35389.1 - 6.1e-07 29.1 3.3 0.0053 16.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KDO35389.1 - 6.8e-07 28.7 44.0 1.4e-05 24.4 11.9 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 KDO35389.1 - 8e-07 28.7 0.3 0.026 14.0 0.0 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KDO35389.1 - 1.1e-06 28.4 0.1 0.013 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KDO35389.1 - 1.1e-05 25.9 0.0 0.28 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KDO35389.1 - 1.7e-05 25.1 0.1 0.14 12.5 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KDO35389.1 - 2.9e-05 23.9 4.3 0.055 13.2 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KDO35389.1 - 5.2e-05 23.3 1.1 0.018 15.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KDO35389.1 - 0.00013 22.3 0.4 0.83 9.9 0.2 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KDO35389.1 - 0.00013 21.3 0.1 0.12 11.7 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 KDO35389.1 - 0.00025 21.5 0.2 1 9.8 0.1 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KDO35389.1 - 0.00026 21.6 0.2 0.13 12.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KDO35389.1 - 0.00054 20.1 1.0 1.4 9.0 0.4 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KDO35389.1 - 0.00058 19.9 1.1 0.48 10.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase PDR_assoc PF08370.11 KDO35389.1 - 0.0032 17.2 0.1 0.012 15.3 0.1 2.0 1 0 0 1 1 1 1 Plant PDR ABC transporter associated Rad17 PF03215.15 KDO35389.1 - 0.0074 16.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 KDO35389.1 - 0.021 14.5 1.2 6.4 6.4 0.9 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KDO35389.1 - 0.032 13.8 3.9 0.34 10.5 0.8 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KDO35389.1 - 0.037 14.2 0.3 9 6.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KDO35389.1 - 0.037 14.1 0.0 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 KDO35389.1 - 0.041 13.8 1.0 29 4.5 0.0 3.2 3 0 0 3 3 3 0 NTPase SbcCD_C PF13558.6 KDO35389.1 - 0.057 13.7 0.0 2.1 8.7 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KDO35389.1 - 0.1 13.0 0.0 23 5.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 KDO35389.1 - 0.11 12.4 0.4 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 KDO35389.1 - 0.12 12.3 3.4 8.3 6.3 0.6 2.4 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KDO35389.1 - 0.17 11.4 0.8 3.8 7.0 0.2 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KDO35389.1 - 0.19 11.7 1.4 5.1 7.1 0.3 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KDO35389.1 - 0.21 11.3 2.0 2 8.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 KDO35389.1 - 0.22 10.9 0.4 8.4 5.7 0.1 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Pkinase_Tyr PF07714.17 KDO35390.1 - 8e-41 140.0 0.0 1.2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO35390.1 - 4.2e-40 137.8 0.0 2.4e-28 99.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain LPG_synthase_TM PF03706.13 KDO35390.1 - 0.0041 16.7 0.1 0.007 15.9 0.1 1.3 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Pkinase_fungal PF17667.1 KDO35390.1 - 0.024 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2681 PF10883.8 KDO35390.1 - 0.066 13.6 0.6 0.13 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) OPA3 PF07047.12 KDO35390.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) FtsL PF04999.13 KDO35390.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Cell division protein FtsL Kinase-like PF14531.6 KDO35390.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_8 PF13855.6 KDO35391.1 - 0.069 12.9 1.5 0.65 9.8 2.0 2.4 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KDO35391.1 - 0.087 13.3 1.0 0.46 11.0 1.2 2.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Bromodomain PF00439.25 KDO35392.1 - 1.2e-21 76.6 0.1 2e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain COBRA1 PF06209.13 KDO35392.1 - 6.7e-12 45.0 0.2 6.7e-12 45.0 0.2 3.2 4 1 0 4 4 4 2 Cofactor of BRCA1 (COBRA1) Adap_comp_sub PF00928.21 KDO35393.1 - 1.5e-68 231.0 0.1 2e-68 230.6 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KDO35393.1 - 0.0064 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TniB PF05621.11 KDO35393.1 - 0.0092 15.4 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Ank_5 PF13857.6 KDO35394.1 - 0.00016 21.9 0.1 0.002 18.4 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO35394.1 - 0.00081 19.9 0.1 0.17 12.5 0.0 3.0 2 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO35394.1 - 0.0067 17.0 0.2 2.8 8.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) EMP70 PF02990.16 KDO35395.1 - 7.3e-204 678.2 7.9 1e-203 677.7 7.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Acetyltransf_10 PF13673.7 KDO35396.1 - 6e-13 48.9 0.0 7.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO35396.1 - 2.1e-08 34.5 0.1 2.9e-08 34.0 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO35396.1 - 0.0007 19.8 0.0 0.0008 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO35397.1 - 9.9e-14 51.4 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO35397.1 - 4.9e-09 36.4 0.0 6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO35397.1 - 2.1e-08 34.5 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO35397.1 - 5.2e-05 23.3 0.0 6.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO35397.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 KDO35397.1 - 0.0079 16.9 0.0 0.017 15.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO35397.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase EF-hand_1 PF00036.32 KDO35398.1 - 9.1e-14 49.9 2.5 1e-05 24.7 0.7 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO35398.1 - 8.9e-12 45.3 2.7 2.9e-11 43.6 2.7 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO35398.1 - 5.4e-11 41.5 0.5 7.1e-05 22.4 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO35398.1 - 1.9e-06 27.6 3.8 0.01 15.6 0.7 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO35398.1 - 3.1e-06 26.4 9.6 0.0012 18.2 0.3 3.3 4 0 0 4 4 4 2 EF hand FUSC PF04632.12 KDO35398.1 - 7.5e-05 21.5 6.2 7.5e-05 21.5 6.2 2.2 2 1 1 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 KDO35398.1 - 7.7 5.2 12.7 2.5 6.8 7.6 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Lactamase_B_2 PF12706.7 KDO35399.1 - 4.7e-30 104.6 0.9 5.9e-30 104.3 0.9 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KDO35399.1 - 3.7e-07 30.2 0.0 8.5e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO35399.1 - 8.8e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KDO35400.1 - 1.1e-25 90.3 0.1 2.3e-25 89.3 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO35400.1 - 5.1e-07 29.9 0.0 1.1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KDO35400.1 - 0.00023 21.1 0.0 0.0014 18.6 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_10 PF13673.7 KDO35401.1 - 4.8e-16 58.9 0.0 6.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO35401.1 - 4.7e-11 43.0 0.0 6.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KDO35401.1 - 2.1e-09 37.6 0.0 3.1e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KDO35401.1 - 0.00013 22.0 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KDO35401.1 - 0.0094 16.1 0.6 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 KDO35401.1 - 0.054 14.2 0.1 0.31 11.8 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KDO35401.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.7 KDO35402.1 - 1e-16 61.1 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO35402.1 - 2e-10 40.9 0.0 2.7e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KDO35402.1 - 2e-07 31.2 0.0 2.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KDO35402.1 - 0.00038 20.5 0.0 0.00043 20.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO35402.1 - 0.00087 19.2 0.0 0.0027 17.6 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KDO35402.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KDO35402.1 - 0.21 11.0 0.0 0.45 10.0 0.0 1.7 1 1 0 1 1 1 0 Putative acetyl-transferase CRAL_TRIO PF00650.20 KDO35403.1 - 1.1e-19 70.8 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KDO35404.1 - 1.3e-18 67.2 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain TFB6 PF17110.5 KDO35404.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH EF-hand_1 PF00036.32 KDO35405.1 - 2.5e-10 39.2 2.5 0.00015 21.0 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KDO35405.1 - 3.6e-10 40.1 0.1 9.2e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO35405.1 - 2.6e-09 36.2 0.1 0.00016 21.3 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KDO35405.1 - 1.5e-05 24.3 1.6 0.013 14.9 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KDO35405.1 - 0.015 15.2 0.4 1.8 8.5 0.3 2.9 3 0 0 3 3 3 0 EF-hand domain pair ALMT PF11744.8 KDO35405.1 - 0.18 10.6 0.0 0.18 10.6 0.0 2.7 3 0 0 3 3 3 0 Aluminium activated malate transporter T7SS_ESX_EspC PF10824.8 KDO35405.1 - 2.3 8.7 5.4 2.8 8.5 0.2 3.0 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm EF-hand_1 PF00036.32 KDO35406.1 - 3.8e-14 51.1 2.2 3.7e-06 26.1 0.3 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KDO35406.1 - 6.4e-13 49.0 3.2 3.6e-12 46.5 3.2 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KDO35406.1 - 3.3e-11 42.2 0.3 0.00012 21.7 0.0 3.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KDO35406.1 - 8.8e-07 28.7 2.7 0.0057 16.5 0.6 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO35406.1 - 1.7e-06 27.3 8.1 0.0022 17.4 0.1 3.5 4 0 0 4 4 4 2 EF hand DUF2207 PF09972.9 KDO35406.1 - 0.02 13.7 6.5 0.017 13.9 1.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EF-hand_9 PF14658.6 KDO35406.1 - 0.11 12.8 0.1 0.46 10.8 0.1 2.1 1 1 0 1 1 1 0 EF-hand domain FUSC_2 PF13515.6 KDO35406.1 - 1.4 9.0 31.1 0.063 13.4 12.7 3.8 2 1 1 3 3 3 0 Fusaric acid resistance protein-like DUF2120 PF09893.9 KDO35406.1 - 3.2 7.9 6.3 1.8 8.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) FUSC PF04632.12 KDO35406.1 - 6.1 5.2 14.8 0.24 9.9 7.7 2.3 2 1 1 3 3 3 0 Fusaric acid resistance protein family CK2S PF15011.6 KDO35407.1 - 0.015 15.2 1.2 0.071 13.0 1.2 1.9 1 1 0 1 1 1 0 Casein Kinase 2 substrate Thiolase_N PF00108.23 KDO35408.1 - 1.8e-87 293.0 1.4 3.2e-87 292.2 1.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KDO35408.1 - 4.4e-45 152.3 4.0 6.4e-44 148.5 0.4 2.7 2 1 0 2 2 2 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KDO35408.1 - 1.2e-05 25.0 4.4 6.5e-05 22.6 1.4 3.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KDO35408.1 - 0.02 13.6 0.4 0.043 12.5 0.3 1.5 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KDO35408.1 - 0.054 13.3 3.3 2.3 8.1 0.2 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CLAMP PF14769.6 KDO35409.1 - 2e-19 69.8 1.2 3.6e-19 69.0 1.2 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 CAP_N PF01213.19 KDO35410.1 - 9.3e-63 212.6 0.0 1.7e-62 211.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KDO35410.1 - 5.5e-51 172.3 4.5 7.6e-51 171.8 4.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KDO35410.1 - 2.3e-05 24.1 3.9 5.7e-05 22.8 3.9 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C Ribosomal_60s PF00428.19 KDO35410.1 - 6.1 7.5 21.8 1.3 9.6 3.5 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-TAZ PF02135.16 KDO35411.1 - 2.5e-07 31.0 17.8 3.5e-07 30.6 16.9 1.6 2 0 0 2 2 2 1 TAZ zinc finger DUF2382 PF09557.10 KDO35412.1 - 1.7 9.0 11.3 2.4 8.4 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) Beta_elim_lyase PF01212.21 KDO35415.1 - 1.4e-31 109.9 0.0 1.7e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase TIR_2 PF13676.6 KDO35416.1 - 8.5e-07 29.6 0.0 2.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 TIR domain Arm PF00514.23 KDO35416.1 - 0.0011 19.0 0.8 19 5.5 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3027 PF11228.8 KDO35416.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) SAM_2 PF07647.17 KDO35416.1 - 0.016 15.3 0.1 0.56 10.4 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) NAD_Gly3P_dh_C PF07479.14 KDO35417.1 - 3.6e-47 160.2 0.0 8.2e-47 159.1 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KDO35417.1 - 8.3e-46 155.8 0.1 1.6e-45 154.9 0.1 1.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.24 KDO35417.1 - 0.11 13.0 0.0 0.75 10.3 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CRAL_TRIO PF00650.20 KDO35419.1 - 3.4e-17 62.6 0.0 5.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Tctex-1 PF03645.13 KDO35420.1 - 4.2e-25 88.0 0.8 5.9e-25 87.5 0.8 1.2 1 0 0 1 1 1 1 Tctex-1 family Peptidase_C25 PF01364.18 KDO35421.1 - 0.054 12.7 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 Cu-oxidase_3 PF07732.15 KDO35422.1 - 3.2e-15 56.2 0.5 2.6e-14 53.3 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KDO35422.1 - 0.00011 21.9 0.1 0.00011 21.9 0.1 3.5 2 1 2 4 4 4 1 Multicopper oxidase DUF3522 PF12036.8 KDO35423.1 - 1.5e-08 35.1 13.0 2.2e-08 34.6 13.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DKCLD PF08068.12 KDO35425.1 - 1.3e-33 114.9 1.3 1e-31 108.8 0.5 3.0 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 KDO35425.1 - 6e-23 81.9 5.0 2.7e-21 76.5 0.7 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KDO35425.1 - 3.2e-21 75.2 0.9 6.1e-21 74.3 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KDO35425.1 - 3.9e-20 71.6 2.4 8.2e-20 70.6 2.4 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KDO35425.1 - 0.0042 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 UPF0113 PUA domain RR_TM4-6 PF06459.12 KDO35425.1 - 0.051 13.4 11.3 0.07 12.9 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KDO35425.1 - 0.16 12.0 24.6 0.37 10.9 24.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.9 KDO35425.1 - 0.91 9.4 17.5 1.9 8.4 17.5 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Coilin_N PF15862.5 KDO35425.1 - 7.1 6.4 16.2 14 5.5 16.2 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUSP PF06337.12 KDO35426.1 - 1.2e-08 35.5 0.0 2.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 DUSP domain RPN2_C PF18004.1 KDO35426.1 - 0.89 9.5 7.0 1.7 8.6 7.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Trypan_PARP PF05887.11 KDO35426.1 - 0.9 9.5 8.5 0.2 11.6 2.4 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIF_alpha PF05793.12 KDO35426.1 - 1.2 7.6 13.7 1.9 7.0 13.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AP3D1 PF06375.11 KDO35426.1 - 3 8.1 13.6 0.83 9.9 10.3 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PDCD2_C PF04194.13 KDO35427.1 - 3.9e-37 128.0 1.0 1.1e-36 126.5 0.0 2.2 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 KDO35427.1 - 5.3e-07 29.6 12.7 5.3e-07 29.6 12.7 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KDO35427.1 - 0.0026 17.6 5.0 0.0026 17.6 5.0 3.5 3 0 0 3 3 3 1 HIT zinc finger HTH_Crp_2 PF13545.6 KDO35427.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Prok-RING_2 PF14445.6 KDO35427.1 - 0.043 14.0 1.6 0.043 14.0 1.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 HNH_2 PF13391.6 KDO35427.1 - 0.067 13.3 0.1 0.43 10.8 0.1 2.4 1 1 0 1 1 1 0 HNH endonuclease BAR PF03114.18 KDO35428.1 - 6.4e-05 22.7 3.5 0.00016 21.4 3.5 1.6 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.10 KDO35428.1 - 0.0022 17.6 5.1 0.36 10.4 1.1 3.1 2 1 1 3 3 3 2 Vps5 C terminal like RPN1_RPN2_N PF17781.1 KDO35428.1 - 0.01 15.3 0.2 3.1 7.1 0.0 2.1 1 1 0 2 2 2 0 RPN1/RPN2 N-terminal domain DUF3829 PF12889.7 KDO35428.1 - 0.056 12.9 1.3 0.73 9.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Syntaxin_2 PF14523.6 KDO35428.1 - 0.62 10.5 5.1 1.1 9.6 2.0 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Beach PF02138.18 KDO35429.1 - 2.2e-24 86.3 0.0 4.4e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PQQ_2 PF13360.6 KDO35429.1 - 0.0019 17.8 0.1 0.0046 16.6 0.1 1.7 1 0 0 1 1 1 1 PQQ-like domain Pkinase PF00069.25 KDO35429.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WD40 PF00400.32 KDO35429.1 - 0.012 16.5 3.8 0.44 11.5 0.2 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KDO35429.1 - 6.3 7.4 6.3 23 5.6 0.2 3.7 4 0 0 4 4 4 0 PQQ-like domain PAP2 PF01569.21 KDO35430.1 - 1.3e-17 63.9 5.3 1.3e-17 63.9 5.3 2.3 2 0 0 2 2 2 2 PAP2 superfamily IQ PF00612.27 KDO35431.1 - 5.7e-28 94.1 67.6 0.00065 19.3 0.3 12.8 13 0 0 13 13 13 11 IQ calmodulin-binding motif AnkUBD PF18418.1 KDO35431.1 - 0.026 14.7 0.1 0.089 12.9 0.1 1.9 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain DUF3573 PF12097.8 KDO35431.1 - 4.4 6.0 5.4 6.8 5.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DDOST_48kD PF03345.14 KDO35433.1 - 1.2e-101 340.6 0.0 2.2e-99 333.1 0.0 2.0 1 1 1 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta PX PF00787.24 KDO35434.1 - 4.8e-06 26.5 0.1 2.1e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 PX domain WW PF00397.26 KDO35435.1 - 1.8e-05 24.7 0.3 4.5e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 KDO35435.1 - 0.0054 17.0 1.8 0.0064 16.8 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase 101 beta sandwich domain Sialidase PF02973.16 KDO35435.1 - 0.069 12.6 1.0 0.11 12.0 1.0 1.3 1 0 0 1 1 1 0 Sialidase, N-terminal domain Sec34 PF04136.15 KDO35435.1 - 0.13 12.1 3.5 4.2 7.2 0.2 2.9 2 1 1 3 3 3 0 Sec34-like family Tup_N PF08581.10 KDO35435.1 - 0.17 12.2 4.7 12 6.3 0.1 3.3 3 0 0 3 3 3 0 Tup N-terminal CENP-H PF05837.12 KDO35435.1 - 0.28 11.6 4.9 1.1 9.7 4.6 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Taxilin PF09728.9 KDO35435.1 - 0.86 8.7 6.6 0.74 8.9 5.2 1.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF1664 PF07889.12 KDO35435.1 - 1.1 9.4 8.1 6.9 6.7 1.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 KDO35435.1 - 1.8 9.2 4.4 12 6.6 3.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 KDO35435.1 - 2.2 9.0 9.7 3.1 8.5 5.0 2.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 KDO35435.1 - 5.7 7.9 8.0 2.7 9.0 0.2 3.1 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain FYVE PF01363.21 KDO35436.1 - 2.9e-11 43.4 12.5 6.1e-11 42.3 12.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pentapeptide_4 PF13599.6 KDO35436.1 - 0.00081 19.5 0.4 0.002 18.3 0.4 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) FYVE_2 PF02318.16 KDO35436.1 - 0.0023 18.1 7.1 0.0053 17.0 7.1 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Pentapeptide_3 PF13576.6 KDO35436.1 - 0.011 15.9 9.3 0.034 14.3 9.3 1.9 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Prok-RING_4 PF14447.6 KDO35436.1 - 2.4 8.1 6.9 7.9 6.4 7.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 HypA PF01155.19 KDO35436.1 - 2.8 8.0 6.7 0.79 9.8 0.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-piccolo PF05715.13 KDO35436.1 - 3.7 7.8 9.4 12 6.1 9.4 1.9 1 1 0 1 1 1 0 Piccolo Zn-finger C1_2 PF03107.16 KDO35436.1 - 7.4 7.0 13.3 0.11 12.9 4.1 2.4 3 0 0 3 3 3 0 C1 domain DZR PF12773.7 KDO35436.1 - 8.5 6.5 10.3 1.4e+02 2.6 10.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon E1-E2_ATPase PF00122.20 KDO35437.1 - 7.4e-46 155.9 4.5 7.9e-46 155.8 1.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KDO35437.1 - 4.8e-35 120.9 25.4 5e-17 62.2 4.1 3.5 4 0 0 4 4 4 3 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KDO35437.1 - 8.8e-24 83.4 0.0 1.7e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KDO35437.1 - 3.8e-19 69.8 0.0 3.2e-09 37.4 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KDO35437.1 - 4.5e-13 48.7 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KDO35437.1 - 5.6e-06 26.3 0.2 0.001 18.8 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Radial_spoke PF04712.12 KDO35438.1 - 1.2e-85 288.4 0.0 4e-50 171.2 0.0 2.1 1 1 1 2 2 2 2 Radial spokehead-like protein zf-RanBP PF00641.18 KDO35439.1 - 6.7e-07 28.5 22.3 7.2e-05 22.0 1.8 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KDO35439.1 - 6.9 6.1 8.7 13 5.3 0.1 3.5 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ABA_GPCR PF12430.8 KDO35440.1 - 7.5e-31 107.3 10.2 7.5e-31 107.3 10.2 2.0 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KDO35440.1 - 4.4e-21 74.7 0.0 1.2e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Fer2_2 PF01799.20 KDO35440.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 [2Fe-2S] binding domain DUF5353 PF17304.2 KDO35440.1 - 7.2 6.4 9.2 0.1 12.3 0.7 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5353) ABC_tran PF00005.27 KDO35441.1 - 9.6e-30 103.9 0.0 2.3e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KDO35441.1 - 8.4e-26 91.2 11.2 1.7e-25 90.2 11.2 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KDO35441.1 - 2e-06 27.4 0.2 1.5e-05 24.6 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KDO35441.1 - 9.6e-06 26.1 0.0 3.1e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KDO35441.1 - 0.00044 20.5 0.7 0.0078 16.5 0.3 2.8 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KDO35441.1 - 0.0012 17.7 0.2 0.0088 14.9 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class ABC_membrane_2 PF06472.15 KDO35441.1 - 0.0033 16.9 0.2 0.0092 15.4 0.2 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 RsgA_GTPase PF03193.16 KDO35441.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KDO35441.1 - 0.0069 16.2 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KDO35441.1 - 0.0086 15.8 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KDO35441.1 - 0.018 15.5 0.1 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KDO35441.1 - 0.019 14.6 0.3 0.65 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KDO35441.1 - 0.019 15.5 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KDO35441.1 - 0.03 14.3 0.0 0.93 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KDO35441.1 - 0.035 14.0 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KDO35441.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KDO35441.1 - 0.045 13.1 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 KDO35441.1 - 0.059 13.6 0.1 0.25 11.6 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KDO35441.1 - 0.072 12.8 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KDO35441.1 - 0.1 13.0 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KDO35441.1 - 0.11 12.4 0.2 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 KDO35441.1 - 0.16 11.6 0.1 0.96 9.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KDO35441.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin zf-MYND PF01753.18 KDO35442.1 - 2.5e-07 30.7 14.4 2.5e-07 30.7 14.4 2.7 2 0 0 2 2 2 1 MYND finger CSRNP_N PF16019.5 KDO35442.1 - 4.5e-06 26.7 14.0 0.007 16.3 0.7 3.4 2 1 0 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus FTCD_C PF04961.12 KDO35442.1 - 0.0027 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Aldedh PF00171.22 KDO35442.1 - 0.046 12.2 0.1 0.071 11.6 0.1 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Orn_Arg_deC_N PF02784.16 KDO35443.1 - 9.2e-38 130.0 0.0 1.2e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KDO35443.1 - 4.3e-11 42.9 0.0 6.5e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain EF-hand_7 PF13499.6 KDO35444.1 - 1.1e-09 38.6 0.3 2.5e-06 27.8 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KDO35444.1 - 3.1e-07 29.6 0.2 0.0082 15.6 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KDO35444.1 - 6.2e-07 28.8 0.0 0.071 13.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KDO35444.1 - 1.2e-05 24.5 0.0 0.23 11.1 0.0 2.8 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KDO35444.1 - 0.009 16.3 3.2 0.84 10.0 0.0 3.2 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Acyltransf_C PF16076.5 KDO35444.1 - 0.11 12.6 1.1 0.42 10.7 0.1 2.5 3 0 0 3 3 3 0 Acyltransferase C-terminus DUF1664 PF07889.12 KDO35445.1 - 0.0021 18.1 2.4 0.21 11.6 0.1 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 KDO35445.1 - 0.008 16.3 0.1 9.9 6.2 0.0 3.2 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) DUF2703 PF10865.8 KDO35445.1 - 0.028 14.6 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2703) Baculo_PEP_C PF04513.12 KDO35445.1 - 0.03 14.4 8.1 1.6 8.8 0.9 3.5 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 KDO35445.1 - 0.035 14.4 6.9 0.75 10.1 0.0 3.9 2 2 2 5 5 5 0 Uncharacterized conserved protein Apolipoprotein PF01442.18 KDO35445.1 - 0.079 12.8 24.7 0.035 14.0 14.6 2.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4618 PF15397.6 KDO35445.1 - 0.12 11.7 3.1 0.35 10.2 1.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) ApoO PF09769.9 KDO35445.1 - 0.13 12.2 0.0 17 5.4 0.0 3.1 2 1 0 3 3 3 0 Apolipoprotein O Rh5 PF18515.1 KDO35445.1 - 0.21 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain Jnk-SapK_ap_N PF09744.9 KDO35445.1 - 0.38 11.0 9.5 0.2 11.8 4.9 2.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 CLZ PF16526.5 KDO35445.1 - 0.56 10.6 8.3 0.6 10.5 0.4 4.0 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 KDO35445.1 - 0.71 10.4 6.3 1.4 9.5 1.6 3.4 3 1 0 3 3 2 0 Cell division protein ZapB Cep57_MT_bd PF06657.13 KDO35445.1 - 0.78 10.2 7.4 4.6 7.8 1.1 3.7 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 KDO35445.1 - 0.92 10.2 14.5 2.6 8.7 0.7 4.7 1 1 2 4 4 4 0 SlyX SK_channel PF03530.14 KDO35446.1 - 1.5e-08 34.6 1.4 1.6e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 KDO35446.1 - 3.9e-06 26.7 5.6 9.9e-06 25.4 5.6 1.7 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 KDO35446.1 - 0.24 11.3 1.4 0.45 10.4 1.4 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel DUF997 PF06196.12 KDO35446.1 - 6.8 6.8 7.5 7.9 6.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DAO PF01266.24 KDO35447.1 - 1.8e-69 235.0 1.4 2.2e-69 234.7 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KDO35447.1 - 1.5e-07 31.5 0.4 1.5e-07 31.5 0.4 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KDO35447.1 - 1.1e-06 28.1 3.7 1.6e-06 27.5 3.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KDO35447.1 - 6.1e-05 22.4 1.7 0.00079 18.7 0.7 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KDO35447.1 - 0.00015 21.2 0.1 0.0044 16.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO35447.1 - 0.00016 20.6 1.1 0.0014 17.5 1.7 1.9 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.18 KDO35447.1 - 0.00058 19.8 0.3 0.0011 18.9 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KDO35447.1 - 0.0014 19.2 0.1 0.024 15.2 0.4 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KDO35447.1 - 0.0035 16.7 0.4 0.0059 15.9 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KDO35447.1 - 0.0069 15.7 0.6 0.011 15.0 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KDO35447.1 - 0.0089 15.3 1.0 0.02 14.2 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KDO35447.1 - 0.023 14.1 6.2 0.038 13.3 6.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KDO35447.1 - 0.025 13.9 0.1 0.059 12.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KDO35447.1 - 0.033 14.3 0.6 0.057 13.6 0.2 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KDO35447.1 - 0.041 13.8 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KDO35447.1 - 0.046 13.3 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.15 KDO35447.1 - 0.16 11.8 0.3 0.37 10.6 0.3 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein GIDA PF01134.22 KDO35447.1 - 0.17 10.9 1.9 0.24 10.4 1.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KDO35447.1 - 0.88 8.5 4.9 0.33 10.0 2.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Ion_trans_2 PF07885.16 KDO35448.1 - 0.00026 20.9 6.6 0.00068 19.5 6.6 1.7 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 KDO35448.1 - 0.0018 18.3 2.1 0.01 15.8 0.2 2.7 3 0 0 3 3 3 1 Calcium-activated SK potassium channel SATase_N PF06426.14 KDO35448.1 - 0.021 15.2 0.4 0.056 13.8 0.4 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Lig_chan PF00060.26 KDO35448.1 - 0.094 12.6 0.4 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel PX PF00787.24 KDO35449.1 - 8.1e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 PX domain APG9 PF04109.16 KDO35450.1 - 3.1e-132 442.0 1.7 3.7e-132 441.7 1.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 cNMP_binding PF00027.29 KDO35451.1 - 6.3e-07 29.4 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Glyco_hydro_3 PF00933.21 KDO35452.1 - 7.2e-58 196.4 0.0 9.7e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KDO35452.1 - 1.6e-38 132.8 0.0 2.6e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KDO35452.1 - 2.9e-11 43.3 0.1 7e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain HHH_5 PF14520.6 KDO35453.1 - 0.0047 17.5 0.0 0.012 16.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain BAF PF02961.14 KDO35453.1 - 0.012 16.1 0.1 0.048 14.1 0.0 2.2 1 1 0 1 1 1 0 Barrier to autointegration factor IMS_HHH PF11798.8 KDO35453.1 - 0.031 14.6 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 IMS family HHH motif Cyclase PF04199.13 KDO35453.1 - 0.15 12.3 0.0 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative cyclase HHH PF00633.23 KDO35453.1 - 0.15 11.9 0.5 0.48 10.4 0.5 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Internalin_N PF12354.8 KDO35455.1 - 0.3 11.2 10.8 5.2 7.2 1.9 3.3 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal DUF424 PF04242.13 KDO35455.1 - 1.9 8.8 3.4 46 4.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF424) SinI PF08671.10 KDO35455.1 - 4.5 7.1 16.0 2.8 7.8 0.0 6.6 9 0 0 9 9 9 0 Anti-repressor SinI TAF1D PF15333.6 KDO35456.1 - 1.1 8.9 6.6 3.5 7.3 6.6 1.8 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Esterase PF00756.20 KDO35457.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ABC2_membrane_3 PF12698.7 KDO35461.1 - 1.8e-53 181.9 52.1 1.8e-33 116.1 14.3 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KDO35461.1 - 1.1e-37 129.6 0.0 4.1e-27 95.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO35461.1 - 2.5e-11 44.0 0.9 2.3e-07 31.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KDO35461.1 - 0.0041 17.6 3.6 0.0058 17.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO35461.1 - 0.0056 16.4 0.5 0.095 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KDO35461.1 - 0.006 16.3 0.3 0.006 16.3 0.3 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KDO35461.1 - 0.041 13.3 0.2 4.2 6.7 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KDO35461.1 - 0.054 13.4 1.3 0.086 12.7 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase ABC2_membrane_2 PF12679.7 KDO35461.1 - 0.11 11.7 0.1 0.11 11.7 0.1 4.0 3 2 1 4 4 4 0 ABC-2 family transporter protein AAA_15 PF13175.6 KDO35461.1 - 0.21 11.2 1.3 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KDO35461.1 - 0.76 9.5 2.0 5.1 6.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KDO35461.1 - 0.87 9.4 4.3 0.95 9.2 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal DUF3584 PF12128.8 KDO35461.1 - 2.9 5.3 3.7 4.5 4.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Hepar_II_III PF07940.13 KDO35462.1 - 4.2e-09 36.4 0.4 8.8e-09 35.3 0.4 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein Fip1 PF05182.13 KDO35462.1 - 0.42 10.2 2.3 0.9 9.1 2.3 1.5 1 0 0 1 1 1 0 Fip1 motif DUF1741 PF08427.10 KDO35463.1 - 0.35 10.5 3.3 0.54 9.9 2.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1741) Atg14 PF10186.9 KDO35463.1 - 9.2 5.2 13.2 14 4.6 12.6 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MatE PF01554.18 KDO35464.1 - 3.5e-33 114.5 34.0 1.5e-19 70.2 15.0 2.3 2 0 0 2 2 2 2 MatE PAPA-1 PF04795.12 KDO35465.1 - 0.011 16.5 5.8 0.011 16.5 5.8 2.0 2 0 0 2 2 2 0 PAPA-1-like conserved region UPF0242 PF06785.11 KDO35465.1 - 0.2 11.8 18.0 0.44 10.6 3.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 KDO35465.1 - 0.26 11.6 10.2 3.4 8.1 3.4 3.4 1 1 2 3 3 3 0 TSC-22/dip/bun family Phage_GPO PF05929.11 KDO35465.1 - 0.5 10.0 9.9 0.58 9.7 9.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RRP36 PF06102.12 KDO35465.1 - 0.53 10.2 16.6 0.89 9.5 16.0 1.5 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 YabA PF06156.13 KDO35465.1 - 0.54 10.9 14.3 2 9.1 9.8 2.5 1 1 2 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 KDO35465.1 - 0.83 9.2 9.9 0.93 9.0 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 KDO35465.1 - 2.7 8.7 14.0 2.7 8.7 4.3 3.5 2 1 2 4 4 4 0 SlyX ZapB PF06005.12 KDO35465.1 - 4.7 7.7 18.8 9.7 6.7 7.0 2.8 1 1 1 3 3 3 0 Cell division protein ZapB LAMTOR PF15454.6 KDO35465.1 - 5.7 7.6 10.0 11 6.7 2.8 2.9 1 1 1 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CHDCT2 PF08074.11 KDO35465.1 - 7.4 6.7 11.7 2.1 8.5 3.9 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Ras PF00071.22 KDO35466.1 - 4.1e-42 143.5 0.0 4.9e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KDO35466.1 - 5.6e-30 104.0 0.0 8.6e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KDO35466.1 - 1.9e-14 53.5 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KDO35466.1 - 1.8e-05 24.2 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KDO35466.1 - 7.1e-05 21.8 0.0 0.00086 18.2 0.1 2.0 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 KDO35466.1 - 0.00096 19.2 0.0 0.0018 18.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KDO35466.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KDO35466.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KDO35466.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KDO35466.1 - 0.036 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2165 PF09933.9 KDO35466.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Sigma54_activat PF00158.26 KDO35466.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC2_membrane_3 PF12698.7 KDO35467.1 - 6.6e-53 180.0 58.1 1.6e-31 109.7 23.7 3.0 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 KDO35467.1 - 6.7e-53 178.9 0.0 2.8e-27 95.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO35467.1 - 1.5e-19 70.9 2.0 2.6e-07 30.8 0.0 3.8 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KDO35467.1 - 4.4e-05 23.0 0.0 1.1 8.7 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KDO35467.1 - 0.00049 19.9 0.9 0.29 10.8 0.1 2.6 3 0 0 3 3 3 2 AAA ATPase domain ABC2_membrane_2 PF12679.7 KDO35467.1 - 0.0011 18.4 33.9 0.0011 18.3 8.5 3.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KDO35467.1 - 0.0045 16.7 0.3 0.0045 16.7 0.3 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KDO35467.1 - 0.0061 17.1 0.2 0.0061 17.1 0.2 2.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KDO35467.1 - 0.012 15.8 0.0 6.1 7.1 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KDO35467.1 - 0.022 14.5 0.5 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 KDO35467.1 - 0.024 14.1 48.6 0.76 9.2 16.5 3.9 3 0 0 3 3 3 0 ABC-2 type transporter RsgA_GTPase PF03193.16 KDO35467.1 - 0.033 14.1 1.7 0.039 13.9 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF2279 PF10043.9 KDO35467.1 - 0.24 12.2 1.9 0.51 11.1 0.2 2.4 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) AAA_24 PF13479.6 KDO35467.1 - 0.27 10.9 0.3 6.8 6.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KDO35467.1 - 1.7 8.4 4.0 2.2 8.0 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 KDO35467.1 - 8.7 5.9 5.9 5 6.7 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 KDO35468.1 - 3.4e-46 157.1 0.5 4.7e-46 156.6 0.5 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KDO35468.1 - 1.1e-24 86.2 0.0 3.4e-24 84.6 0.0 1.9 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KDO35468.1 - 0.0045 16.9 0.1 3 7.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 KDO35468.1 - 0.0048 16.9 0.0 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KDO35468.1 - 0.0057 16.2 0.3 0.19 11.2 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KDO35468.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KDO35468.1 - 0.022 15.1 0.0 0.084 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KDO35468.1 - 0.038 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 KDO35468.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 KDO35468.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 KDO35468.1 - 0.11 12.2 0.0 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cellulase PF00150.18 KDO35470.1 - 1.1e-24 87.3 4.0 1.5e-24 86.9 4.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 KDO35470.1 - 0.031 13.7 0.1 0.17 11.3 0.1 2.1 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Palm_thioest PF02089.15 KDO35471.1 - 2.2e-70 237.2 0.0 2.6e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KDO35471.1 - 0.00075 20.2 0.6 0.013 16.1 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KDO35471.1 - 0.0054 16.3 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KDO35471.1 - 0.013 14.8 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO35471.1 - 0.064 12.9 0.1 0.15 11.7 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 KDO35472.1 - 1.1e-77 261.2 0.0 1.3e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KDO35472.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DEAD PF00270.29 KDO35473.1 - 1.3e-18 67.4 0.0 2.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KDO35473.1 - 2e-17 63.6 5.6 5e-17 62.4 5.6 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 KDO35473.1 - 2e-14 53.9 0.0 1.7e-13 50.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO35473.1 - 0.011 15.8 0.0 0.053 13.5 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KDO35476.1 - 1.8e-20 73.2 18.0 3.4e-20 72.3 18.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DSPc PF00782.20 KDO35477.1 - 5.8e-30 103.8 0.0 8e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO35477.1 - 0.0034 17.0 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Reprolysin_5 PF13688.6 KDO35479.1 - 2.8e-16 60.2 0.9 2.8e-16 60.2 0.9 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KDO35479.1 - 1.7e-12 47.5 1.8 1.2e-11 44.7 1.8 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KDO35479.1 - 1.5e-09 38.0 0.2 3.5e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KDO35479.1 - 2.2e-08 34.7 0.3 9.3e-08 32.6 0.3 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 KDO35479.1 - 2.8e-05 24.2 7.2 0.00015 21.9 7.2 2.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain Oxidored_q2 PF00420.24 KDO35479.1 - 0.005 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM154 PF15102.6 KDO35479.1 - 0.39 10.6 0.0 0.39 10.6 0.0 4.4 3 2 0 3 3 3 0 TMEM154 protein family His_Phos_2 PF00328.22 KDO35480.1 - 1.8e-12 47.3 0.0 4e-11 42.9 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) FAD_binding_1 PF00667.20 KDO35481.1 - 2.3e-18 66.6 0.0 3.6e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KDO35481.1 - 2e-14 54.2 0.0 3.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 KDO35481.1 - 7.8e-06 25.5 2.8 1.6e-05 24.4 2.8 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal RRM_1 PF00076.22 KDO35482.1 - 2.2e-56 187.6 0.0 5.7e-19 67.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO35482.1 - 8.2e-11 41.9 0.0 2.6e-05 24.2 0.0 3.8 3 2 0 3 3 3 3 RNA recognition motif RRM_occluded PF16842.5 KDO35482.1 - 1.4e-07 31.2 0.0 0.033 14.0 0.0 3.7 3 2 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KDO35482.1 - 5.3e-06 26.3 0.0 0.49 10.4 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KDO35482.1 - 0.00022 20.8 0.0 0.054 13.1 0.0 3.0 1 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KDO35482.1 - 0.0013 18.7 0.0 0.6 10.2 0.0 3.0 3 1 0 3 3 3 1 RNA binding motif RL PF17797.1 KDO35482.1 - 0.021 14.8 0.0 2.7 8.0 0.0 3.1 3 0 0 3 3 3 0 RL domain PHM7_cyt PF14703.6 KDO35482.1 - 0.022 15.0 0.0 2.8 8.2 0.0 3.6 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DUF4651 PF15513.6 KDO35482.1 - 0.03 14.1 0.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) RRM_Rrp7 PF17799.1 KDO35482.1 - 0.053 13.3 0.0 2.8 7.7 0.0 3.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain PPR PF01535.20 KDO35483.1 - 2e-06 27.7 1.1 3.7 8.0 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.6 KDO35483.1 - 2e-06 27.9 0.0 0.017 15.3 0.0 4.8 4 1 0 4 4 4 2 PPR repeat family PPR_long PF17177.4 KDO35483.1 - 0.0022 17.4 0.2 0.054 12.8 0.0 2.8 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP Ank_4 PF13637.6 KDO35484.1 - 2.4e-27 94.9 5.2 3e-11 43.6 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KDO35484.1 - 2.3e-19 69.8 0.1 1.7e-10 41.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KDO35484.1 - 6.1e-18 64.7 4.7 3.1e-07 30.5 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO35484.1 - 1.6e-15 55.7 0.6 0.0024 18.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KDO35484.1 - 7.1e-14 51.5 5.8 3e-05 24.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeat Gp58 PF07902.11 KDO35485.1 - 4.2e-06 25.3 3.8 6.6e-06 24.7 3.8 1.3 1 0 0 1 1 1 1 gp58-like protein DUF2333 PF10095.9 KDO35485.1 - 0.0029 16.7 0.1 0.0029 16.7 0.1 2.7 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2333) Baculo_PEP_C PF04513.12 KDO35485.1 - 0.02 14.9 21.1 0.52 10.3 0.9 5.1 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KDO35485.1 - 0.021 14.7 41.3 0.82 9.5 6.0 3.6 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 KDO35485.1 - 0.064 13.4 5.5 1.9 8.6 1.2 3.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family GP3_package PF16677.5 KDO35485.1 - 0.094 12.9 0.3 0.29 11.3 0.2 1.8 1 1 0 1 1 1 0 DNA-packaging protein gp3 DUF4795 PF16043.5 KDO35485.1 - 0.14 11.7 11.6 2.4 7.7 5.5 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) T3SS_needle_F PF09392.10 KDO35485.1 - 1.4 9.1 5.0 4 7.7 0.2 3.4 3 2 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF ApoLp-III PF07464.11 KDO35485.1 - 1.8 8.6 11.7 0.33 11.1 6.0 2.6 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ADIP PF11559.8 KDO35485.1 - 2.3 8.3 24.3 0.6 10.2 0.2 5.1 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding COG2 PF06148.11 KDO35485.1 - 2.4 8.2 11.7 0.54 10.3 0.3 4.1 1 1 4 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC53 PF10152.9 KDO35485.1 - 3.4 8.1 5.5 2.6 8.4 0.2 2.9 1 1 0 2 2 2 0 Subunit CCDC53 of WASH complex ABC_tran_CTD PF16326.5 KDO35485.1 - 3.9 7.8 20.3 0.45 10.8 0.2 5.9 3 1 2 5 5 5 0 ABC transporter C-terminal domain HSP70 PF00012.20 KDO35486.1 - 1.1e-233 776.9 21.9 7.4e-124 414.1 4.5 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KDO35486.1 - 8.3e-14 51.1 3.5 1.6e-11 43.6 0.1 3.4 3 1 0 4 4 4 2 MreB/Mbl protein Radial_spoke_3 PF06098.11 KDO35486.1 - 3.1e-05 23.4 5.8 3.1e-05 23.4 5.8 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 Hydantoinase_A PF01968.18 KDO35486.1 - 0.00028 20.2 2.5 0.23 10.7 0.2 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KDO35486.1 - 0.013 15.3 0.3 0.064 13.0 0.0 2.3 2 1 1 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3486 PF11985.8 KDO35486.1 - 0.31 11.4 0.0 0.31 11.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3486) FtsA PF14450.6 KDO35486.1 - 1.4 9.4 6.9 66 4.0 2.8 3.7 2 1 0 2 2 2 0 Cell division protein FtsA Tox-REase-7 PF15649.6 KDO35487.1 - 0.059 13.7 0.2 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 Med30 PF11315.8 KDO35487.1 - 3.7 7.7 10.3 0.59 10.3 1.6 2.7 2 1 0 2 2 2 0 Mediator complex subunit 30 MORN PF02493.20 KDO35488.1 - 2.7e-21 74.1 28.3 1.5e-06 27.8 0.0 6.8 6 1 0 6 6 6 5 MORN repeat ThiF PF00899.21 KDO35490.1 - 1.3e-89 299.8 0.0 1.1e-63 214.9 0.0 2.8 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KDO35490.1 - 2.1e-65 221.2 0.3 3.5e-65 220.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 KDO35490.1 - 8.2e-16 58.0 0.0 2.8e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 KDO35490.1 - 4.7e-10 39.5 0.2 2.8e-08 33.8 0.2 2.8 1 1 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain VirE3 PF06661.11 KDO35491.1 - 0.0098 15.2 3.4 0.015 14.6 3.4 1.3 1 0 0 1 1 1 1 VirE3 Pkinase PF00069.25 KDO35492.1 - 6.1e-61 206.1 0.3 8.8e-61 205.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35492.1 - 1.9e-40 138.8 0.0 3.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KDO35492.1 - 1.5e-06 27.3 0.3 7.6e-06 24.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KDO35492.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO35492.1 - 0.044 13.7 5.4 0.4 10.6 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KDO35492.1 - 0.044 12.7 0.0 0.09 11.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain zf-piccolo PF05715.13 KDO35492.1 - 0.095 12.9 0.6 0.17 12.0 0.6 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4_3 PF13920.6 KDO35493.1 - 4.4e-14 52.1 14.0 6.6e-14 51.5 14.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO35493.1 - 6.1e-07 29.2 14.8 1e-06 28.5 14.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KDO35493.1 - 3.5e-05 24.0 16.8 6.1e-05 23.3 16.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C4H2 PF10146.9 KDO35493.1 - 0.041 14.2 0.2 0.078 13.3 0.2 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein zf-RING_5 PF14634.6 KDO35493.1 - 0.058 13.4 15.0 0.095 12.7 15.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.21 KDO35494.1 - 1e-11 44.8 12.7 2.4e-11 43.6 12.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 KDO35494.1 - 6.7e-06 25.7 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO35494.1 - 0.12 12.6 12.4 0.38 11.0 12.4 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Kinesin PF00225.23 KDO35495.1 - 2.3e-109 365.4 0.0 4e-109 364.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KDO35495.1 - 1.1e-28 100.0 2.3 1.3e-28 99.8 0.0 2.2 3 0 0 3 3 3 1 Microtubule binding APG17 PF04108.12 KDO35495.1 - 0.0027 16.9 25.8 0.0064 15.7 12.0 3.4 2 2 0 2 2 2 1 Autophagy protein Apg17 Apolipoprotein PF01442.18 KDO35495.1 - 0.011 15.6 43.1 16 5.3 4.7 4.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain AAA_7 PF12775.7 KDO35495.1 - 0.033 13.7 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SHE3 PF17078.5 KDO35495.1 - 0.071 12.8 13.1 0.018 14.7 1.3 3.4 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Baculo_PEP_C PF04513.12 KDO35495.1 - 0.085 12.9 24.0 1 9.4 0.1 4.5 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 KDO35495.1 - 0.087 13.1 0.0 0.087 13.1 0.0 3.8 3 1 1 4 4 4 0 AAA domain Bac_DnaA PF00308.18 KDO35495.1 - 0.09 12.6 2.8 0.098 12.5 0.0 2.4 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_16 PF13191.6 KDO35495.1 - 0.52 10.7 0.0 0.52 10.7 0.0 3.7 2 1 0 2 2 1 0 AAA ATPase domain Sec8_exocyst PF04048.14 KDO35495.1 - 2.6 7.9 16.1 3.1 7.7 0.0 4.7 4 1 2 6 6 6 0 Sec8 exocyst complex component specific domain ACPS PF01648.20 KDO35496.1 - 7.5e-17 61.5 0.0 3.8e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily ICL PF00463.21 KDO35497.1 - 9.4e-202 671.2 1.9 1.2e-200 667.5 1.9 1.9 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KDO35497.1 - 3.9e-13 49.4 0.2 2.1e-12 47.0 0.1 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PIG-P PF08510.12 KDO35498.1 - 0.5 10.3 4.6 0.12 12.3 0.7 1.9 2 0 0 2 2 2 0 PIG-P FYVE_2 PF02318.16 KDO35498.1 - 1.9 8.7 5.2 3.6 7.8 2.1 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PX PF00787.24 KDO35499.1 - 3.3e-07 30.3 0.2 1.4e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 PX domain GCIP PF13324.6 KDO35499.1 - 0.018 14.7 0.9 0.039 13.5 0.9 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Peptidase_U57 PF05582.12 KDO35499.1 - 0.1 11.9 0.2 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 YabG peptidase U57 Glycos_transf_N PF04413.16 KDO35500.1 - 2.1e-48 164.3 0.0 3.8e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) SET PF00856.28 KDO35500.1 - 2.7e-20 73.4 0.2 9.9e-10 39.1 0.1 3.4 2 2 0 2 2 2 2 SET domain Peptidase_M73 PF12389.8 KDO35500.1 - 0.16 11.8 0.0 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase QVR PF17064.5 KDO35500.1 - 0.22 11.8 9.8 0.3 11.4 0.8 2.5 2 0 0 2 2 2 0 Sleepless protein RRM_1 PF00076.22 KDO35501.1 - 6.7e-33 112.3 0.0 1.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KDO35501.1 - 5.2e-14 52.1 0.1 3.6e-06 27.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KDO35501.1 - 0.00017 21.5 0.1 0.085 12.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KDO35501.1 - 0.031 14.0 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Pro_CA PF00484.19 KDO35502.1 - 3.3e-50 170.4 0.1 4.6e-50 169.9 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Nuf2 PF03800.14 KDO35503.1 - 8.1e-33 113.5 0.0 8.1e-33 113.5 0.0 2.3 3 0 0 3 3 3 1 Nuf2 family DHR10 PF18595.1 KDO35503.1 - 3.2e-20 72.3 22.2 3.2e-20 72.3 22.2 4.2 2 2 1 4 4 4 1 Designed helical repeat protein 10 domain Baculo_LEF-11 PF06385.12 KDO35503.1 - 0.0023 18.4 1.7 0.0071 16.8 1.7 1.8 1 0 0 1 1 1 1 Baculovirus LEF-11 protein DUF3584 PF12128.8 KDO35503.1 - 0.21 9.1 46.7 0.17 9.4 45.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lipase_GDSL_2 PF13472.6 KDO35503.1 - 1.6 9.1 3.8 1.6 9.1 0.8 2.4 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family WbqC PF08889.11 KDO35503.1 - 4.7 7.0 11.4 0.47 10.3 2.6 2.4 1 1 1 2 2 2 0 WbqC-like protein family PseudoU_synth_2 PF00849.22 KDO35504.1 - 5.9e-26 91.5 0.1 1.1e-25 90.6 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ank_2 PF12796.7 KDO35505.1 - 1.8e-43 147.0 8.5 3.5e-16 59.5 0.1 6.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) RTP1_C1 PF10363.9 KDO35505.1 - 1.5e-29 102.5 0.2 6.5e-29 100.4 0.2 2.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Ank_4 PF13637.6 KDO35505.1 - 3.7e-29 100.7 14.6 6.3e-07 29.8 0.3 8.3 2 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO35505.1 - 2.1e-27 94.8 15.7 7.9e-07 29.2 0.2 7.8 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO35505.1 - 3.8e-25 85.2 16.8 0.00015 21.9 0.0 11.1 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 KDO35505.1 - 4.9e-19 67.9 38.7 0.0001 22.6 0.0 11.6 11 0 0 11 11 11 6 Ankyrin repeat F-box PF00646.33 KDO35505.1 - 6.1e-06 26.0 0.4 2.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain RTP1_C2 PF10304.9 KDO35505.1 - 0.00036 20.2 0.0 0.00097 18.8 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 F-box-like PF12937.7 KDO35505.1 - 0.011 15.6 0.4 0.072 13.0 0.0 2.5 2 0 0 2 2 2 0 F-box-like TMEM187 PF15100.6 KDO35505.1 - 0.056 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 TMEM187 protein family P5CR_dimer PF14748.6 KDO35506.1 - 8.6e-36 122.3 0.3 1.6e-35 121.4 0.3 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KDO35506.1 - 3.9e-17 62.6 0.1 9.1e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KDO35506.1 - 3.2e-05 24.1 0.1 8.5e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KDO35506.1 - 0.00017 21.3 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KDO35506.1 - 0.0014 18.6 0.4 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KDO35506.1 - 0.0028 17.6 0.1 0.0028 17.6 0.1 2.1 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KDO35506.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.15 KDO35506.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_7 PF13241.6 KDO35506.1 - 0.061 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Prefoldin_2 PF01920.20 KDO35507.1 - 9.5e-17 60.9 5.1 1.1e-16 60.6 5.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 KDO35507.1 - 0.00028 20.6 8.9 0.0043 16.8 2.1 2.8 2 1 1 3 3 3 2 Septum formation initiator DUF4140 PF13600.6 KDO35507.1 - 0.022 15.2 9.5 0.4 11.1 2.7 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5082 PF16888.5 KDO35507.1 - 0.024 14.9 5.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TerB_C PF15615.6 KDO35507.1 - 0.027 14.8 3.3 0.036 14.3 3.3 1.2 1 0 0 1 1 1 0 TerB-C domain FlaC_arch PF05377.11 KDO35507.1 - 0.084 13.3 2.9 0.44 11.0 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3847 PF12958.7 KDO35507.1 - 0.099 12.8 6.4 0.11 12.6 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) FliD_N PF02465.18 KDO35507.1 - 0.1 13.3 4.6 10 6.9 2.4 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spectrin PF00435.21 KDO35507.1 - 0.15 12.6 7.4 0.71 10.4 2.8 2.2 1 1 1 2 2 2 0 Spectrin repeat bZIP_2 PF07716.15 KDO35507.1 - 0.33 11.1 8.6 5.8 7.1 4.0 2.4 2 0 0 2 2 2 0 Basic region leucine zipper YabA PF06156.13 KDO35507.1 - 0.57 10.9 4.8 7.2 7.3 4.0 2.0 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 KDO35507.1 - 0.95 10.0 4.3 3.5 8.1 0.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 KDO35507.1 - 1.6 9.0 9.4 1.1 9.5 0.3 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KDO35507.1 - 2.6 8.6 14.7 2.5 8.6 12.3 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region EMC3_TMCO1 PF01956.16 KDO35507.1 - 4 7.1 5.0 1.1 9.0 1.3 1.7 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Aa_trans PF01490.18 KDO35508.1 - 1.2e-57 195.5 18.9 1.4e-57 195.3 18.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KDO35508.1 - 5.3e-08 32.3 15.6 5.3e-08 32.3 15.6 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3687 PF12459.8 KDO35508.1 - 0.0082 15.6 0.1 0.0082 15.6 0.1 2.5 2 0 0 2 2 2 1 D-Ala-teichoic acid biosynthesis protein MscS_TM PF12794.7 KDO35508.1 - 2.1 7.1 13.5 0.49 9.2 2.9 3.0 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 BBS2_Mid PF14783.6 KDO35509.1 - 1.6e-05 24.9 0.0 0.00041 20.4 0.0 2.9 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 KDO35509.1 - 0.005 15.7 0.1 0.19 10.4 0.0 2.3 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal CNV-Replicase_N PF16688.5 KDO35509.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 Tmemb_185A PF10269.9 KDO35510.1 - 1.9e-06 27.8 14.0 0.0082 15.9 2.2 3.0 2 1 0 2 2 2 2 Transmembrane Fragile-X-F protein Filament PF00038.21 KDO35511.1 - 0.0017 18.0 26.6 0.0017 18.0 26.6 5.9 2 1 2 5 5 5 1 Intermediate filament protein Nsp1_C PF05064.13 KDO35511.1 - 0.0055 16.5 1.2 0.0055 16.5 1.2 7.3 6 3 3 9 9 9 1 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 KDO35511.1 - 0.013 15.5 10.5 0.013 15.5 10.5 7.9 3 1 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 KDO35511.1 - 0.22 11.5 55.8 0.2 11.7 2.6 6.5 5 1 2 7 7 7 0 Laminin Domain II PI_PP_I PF18363.1 KDO35511.1 - 0.48 10.6 7.7 11 6.3 0.6 4.6 4 1 1 5 5 5 0 Phosphoinositide phosphatase insertion domain Fib_alpha PF08702.10 KDO35511.1 - 0.65 10.2 56.4 0.026 14.7 7.5 7.3 4 1 3 8 8 8 0 Fibrinogen alpha/beta chain family EGF_alliinase PF04863.13 KDO35512.1 - 0.046 14.1 1.0 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 Alliinase EGF-like domain RabGAP-TBC PF00566.18 KDO35513.1 - 4e-35 121.4 0.0 2.7e-34 118.7 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF5400 PF17379.2 KDO35513.1 - 0.12 12.9 1.9 5.3 7.6 0.4 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5400) F-box-like PF12937.7 KDO35514.1 - 0.0031 17.4 0.3 0.013 15.4 0.3 2.1 1 0 0 1 1 1 1 F-box-like EAGR_box PF16713.5 KDO35514.1 - 0.088 12.5 0.6 0.21 11.3 0.6 1.6 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box Chibby PF14645.6 KDO35515.1 - 2.5e-05 24.7 1.1 3.6e-05 24.2 0.3 1.7 1 1 1 2 2 2 1 Chibby family bZIP_2 PF07716.15 KDO35515.1 - 0.024 14.7 1.8 0.024 14.7 1.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 KDO35515.1 - 0.058 13.7 2.0 0.093 13.1 0.3 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KDO35515.1 - 0.062 13.4 1.2 0.062 13.4 1.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor PH PF00169.29 KDO35517.1 - 6.8e-12 45.8 0.1 1.5e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KDO35517.1 - 5e-11 43.0 0.5 8.9e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KDO35517.1 - 1e-06 28.9 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain COPIIcoated_ERV PF07970.12 KDO35518.1 - 2.3e-31 109.4 0.1 4.2e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KDO35518.1 - 8.2e-26 90.2 0.2 1.8e-25 89.1 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 KDO35518.1 - 1.5e-20 73.1 0.0 3.1e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO35518.1 - 0.00091 19.7 0.1 0.0039 17.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain SOR_SNZ PF01680.17 KDO35519.1 - 2.5e-110 367.1 11.6 2.5e-110 367.1 11.6 1.7 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 KDO35519.1 - 9.9e-09 34.9 11.5 1.7e-08 34.1 0.9 2.8 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KDO35519.1 - 6.8e-06 25.4 0.6 0.032 13.3 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KDO35519.1 - 0.0011 18.5 1.1 0.016 14.7 0.2 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein OMPdecase PF00215.24 KDO35519.1 - 0.002 17.8 0.4 0.9 9.1 0.0 2.4 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family IMPDH PF00478.25 KDO35519.1 - 0.0091 15.0 3.0 0.012 14.6 3.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 KDO35519.1 - 0.016 14.4 2.3 0.046 12.9 0.1 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KDO35519.1 - 0.03 13.5 0.2 0.66 9.1 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 KDO35519.1 - 0.031 14.3 0.1 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 KDO35519.1 - 0.48 9.8 10.1 0.21 10.9 1.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Vps51 PF08700.11 KDO35520.1 - 1.8e-22 79.2 1.6 8e-22 77.1 0.9 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 KDO35520.1 - 2.2e-12 47.2 7.5 5.1e-12 46.0 7.5 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 KDO35520.1 - 2.4e-12 46.2 4.5 2.4e-12 46.2 4.5 1.7 2 0 0 2 2 2 1 Dor1-like family COG5 PF10392.9 KDO35520.1 - 2.8e-05 24.3 1.1 6.9e-05 23.0 0.4 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Zw10 PF06248.13 KDO35520.1 - 4.2e-05 22.3 6.2 7e-05 21.6 6.2 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG2 PF06148.11 KDO35520.1 - 5.1e-05 23.4 1.6 0.00015 21.9 1.6 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 KDO35520.1 - 0.00027 20.3 6.6 0.00053 19.4 6.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex SRP1_TIP1 PF00660.17 KDO35520.1 - 0.054 13.6 0.3 0.68 10.0 0.0 2.8 2 1 0 2 2 2 0 Seripauperin and TIP1 family BORCS6 PF10157.9 KDO35520.1 - 0.083 13.1 1.2 0.24 11.6 1.2 1.9 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 HIP1_clath_bdg PF16515.5 KDO35520.1 - 0.11 13.1 1.3 0.39 11.3 1.3 2.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rhodanese PF00581.20 KDO35523.1 - 5e-21 75.2 0.0 2.4e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain CAP PF00188.26 KDO35524.1 - 1.2e-08 35.8 0.0 1.7e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Lactamase_B_2 PF12706.7 KDO35526.1 - 1.1e-11 44.7 0.4 5.6e-11 42.3 0.4 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KDO35526.1 - 0.0073 16.3 3.7 0.021 14.8 2.7 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Ran_BP1 PF00638.18 KDO35527.1 - 1.7e-07 31.5 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Stealth_CR2 PF11380.8 KDO35529.1 - 9.5e-44 148.0 0.2 3.1e-42 143.1 0.0 2.4 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KDO35529.1 - 8.4e-17 60.8 8.0 2.1e-16 59.5 8.0 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KDO35529.1 - 8.8e-14 51.7 29.7 2e-08 34.6 8.9 2.7 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 KDO35529.1 - 2.6e-11 43.1 1.2 5.2e-11 42.1 1.2 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 KDO35529.1 - 7.8e-10 38.5 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR2 PF11380.8 KDO35530.1 - 5.9e-44 148.7 0.0 6.5e-43 145.3 0.0 2.3 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KDO35530.1 - 2.2e-16 59.5 6.0 4.6e-16 58.5 6.0 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KDO35530.1 - 7e-13 48.8 28.5 2.2e-07 31.2 8.7 2.8 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 KDO35530.1 - 2.5e-11 43.1 1.2 5.1e-11 42.1 1.2 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 KDO35530.1 - 1.8e-08 34.2 0.0 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR2 PF11380.8 KDO35531.1 - 1.3e-26 92.9 0.0 9.7e-24 83.6 0.0 3.3 2 1 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KDO35531.1 - 8.7e-17 60.8 3.5 8.7e-17 60.8 3.5 2.8 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KDO35531.1 - 1.6e-14 54.0 23.5 3.2e-07 30.7 6.3 2.6 2 0 0 2 2 2 2 LNR domain Stealth_CR4 PF17103.5 KDO35531.1 - 1.1e-13 50.8 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 KDO35531.1 - 4.8e-11 42.2 3.5 9.7e-11 41.2 3.5 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 EF-hand_6 PF13405.6 KDO35531.1 - 0.013 15.3 0.0 0.054 13.4 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 KDO35531.1 - 0.038 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 KDO35531.1 - 0.13 11.8 0.0 0.49 10.0 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KDO35531.1 - 0.18 11.4 0.0 0.61 9.8 0.0 1.9 1 0 0 1 1 1 0 EF hand SHIPPO-rpt PF07004.12 KDO35534.1 - 4.8e-11 43.0 22.3 0.19 12.7 0.3 8.3 8 0 0 8 8 8 6 Sperm-tail PG-rich repeat Hexapep PF00132.24 KDO35535.1 - 4e-07 29.5 10.4 9.9e-05 21.9 4.3 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) BT1 PF03092.16 KDO35535.1 - 0.018 13.3 0.1 0.018 13.3 0.1 3.2 3 0 0 3 3 3 0 BT1 family Fucokinase PF07959.12 KDO35535.1 - 0.032 13.2 1.6 0.053 12.5 0.8 1.6 1 1 0 1 1 1 0 L-fucokinase UPF0242 PF06785.11 KDO35535.1 - 0.035 14.2 2.4 0.31 11.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus TRP PF06011.12 KDO35536.1 - 7.3e-09 34.9 29.5 5.1e-08 32.1 29.5 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel MIG-14_Wnt-bd PF06664.12 KDO35536.1 - 0.0017 17.6 6.0 0.0017 17.6 6.0 2.6 3 0 0 3 3 3 1 Wnt-binding factor required for Wnt secretion OppC_N PF12911.7 KDO35536.1 - 1.9 8.5 0.0 1.9 8.5 0.0 4.7 4 1 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Chordopox_A13L PF05961.11 KDO35536.1 - 2.7 8.3 7.4 17 5.8 0.0 4.3 4 0 0 4 4 4 0 Chordopoxvirus A13L protein DUF443 PF04276.12 KDO35536.1 - 3.9 7.2 9.9 0.12 12.2 1.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Pkinase PF00069.25 KDO35537.1 - 1e-53 182.4 0.0 1.5e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cyclin_N PF00134.23 KDO35537.1 - 7e-33 113.1 6.4 9.7e-33 112.6 2.7 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KDO35537.1 - 3.3e-21 75.6 0.7 6.7e-21 74.6 0.7 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase_Tyr PF07714.17 KDO35537.1 - 3.8e-15 55.9 0.0 6.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 KDO35537.1 - 5.2e-09 35.9 0.0 5.3e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KDO35537.1 - 0.0019 18.0 0.1 0.0051 16.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Kdo PF06293.14 KDO35537.1 - 0.02 14.2 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Complex1_LYR PF05347.15 KDO35539.1 - 8e-11 41.8 0.0 9.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KDO35539.1 - 0.013 16.1 0.1 0.017 15.7 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_2 PF13233.6 KDO35539.1 - 0.023 15.4 0.0 0.027 15.2 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Methyltransf_16 PF10294.9 KDO35540.1 - 1.3e-20 73.8 0.0 1.7e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KDO35540.1 - 7e-14 51.9 0.1 9.3e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KDO35540.1 - 7.2e-08 32.2 0.1 1.1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KDO35540.1 - 2.3e-06 28.2 0.1 3.8e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KDO35540.1 - 3.1e-05 23.9 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO35540.1 - 0.00017 21.4 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KDO35540.1 - 0.00091 18.9 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KDO35540.1 - 0.00095 19.0 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KDO35540.1 - 0.002 18.7 0.0 0.0031 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KDO35540.1 - 0.0023 17.0 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KDO35540.1 - 0.0087 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KDO35540.1 - 0.014 16.1 0.1 0.021 15.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KDO35540.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MethyltransfD12 PF02086.15 KDO35540.1 - 0.23 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase GatB_N PF02934.15 KDO35541.1 - 4.7e-106 354.1 0.1 6e-106 353.8 0.1 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KDO35541.1 - 1.3e-39 135.4 0.0 2.8e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 GatB domain CSRNP_N PF16019.5 KDO35542.1 - 7.6e-05 22.7 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus AA_permease_2 PF13520.6 KDO35543.1 - 2.1e-45 155.3 42.4 2.1e-45 155.3 42.4 1.9 1 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KDO35543.1 - 1.4e-33 116.2 41.5 2.5e-33 115.4 41.5 1.4 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KDO35543.1 - 2.6e-19 69.0 7.9 2.6e-19 69.0 7.9 3.9 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.13 KDO35543.1 - 5.6e-06 25.4 14.7 5.6e-06 25.4 14.7 3.2 2 1 0 2 2 2 1 Spore germination protein HNF-1A_C PF04813.12 KDO35544.1 - 0.92 10.3 4.3 0.25 12.1 0.6 1.8 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Cyclin_C_2 PF16899.5 KDO35545.1 - 1.2e-11 44.9 1.2 1.3e-10 41.6 0.1 2.7 2 1 1 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KDO35545.1 - 9.4e-06 25.4 0.5 1.9e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KDO35545.1 - 0.0018 18.3 0.0 0.0056 16.7 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Peptidase_S49_N PF08496.10 KDO35545.1 - 3.5 7.7 13.5 6.8 6.7 13.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2347 PF09804.9 KDO35545.1 - 4.5 6.8 7.1 5.8 6.4 5.7 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) PPR_2 PF13041.6 KDO35546.1 - 1.5e-42 143.6 0.0 1.2e-07 31.8 0.0 10.3 8 2 2 10 10 10 9 PPR repeat family PPR PF01535.20 KDO35546.1 - 8e-29 97.9 0.0 0.027 14.7 0.0 12.6 14 0 0 14 14 14 6 PPR repeat PPR_3 PF13812.6 KDO35546.1 - 2e-19 69.4 0.0 0.0097 16.0 0.0 10.1 8 2 4 12 12 12 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 KDO35546.1 - 6.9e-14 51.2 0.2 0.31 10.8 0.0 9.7 11 0 0 11 11 11 2 PPR repeat PPR_long PF17177.4 KDO35546.1 - 2.6e-13 49.8 6.4 0.002 17.6 0.0 6.9 3 2 3 7 7 7 3 Pentacotripeptide-repeat region of PRORP TPR_4 PF07721.14 KDO35546.1 - 0.036 14.7 8.8 4 8.3 0.1 5.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KDO35546.1 - 0.1 13.2 10.2 4.2 8.1 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KDO35546.1 - 0.4 10.3 4.9 5 6.8 0.1 4.5 3 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_19 PF14559.6 KDO35546.1 - 1.4 9.5 16.1 0.24 11.9 0.3 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KDO35546.1 - 7 7.7 30.0 70 4.7 0.0 11.2 10 3 4 14 14 14 0 Tetratricopeptide repeat DEAD PF00270.29 KDO35547.1 - 5.2e-40 137.1 0.1 1.2e-39 135.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO35547.1 - 2.9e-28 98.4 0.0 1.5e-27 96.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO35547.1 - 3.4e-08 33.7 0.9 2.4e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SDA1 PF05285.12 KDO35547.1 - 0.00014 21.5 32.2 0.00033 20.2 32.2 1.6 1 0 0 1 1 1 1 SDA1 AAA_22 PF13401.6 KDO35547.1 - 0.16 12.2 0.3 19 5.5 0.0 3.2 2 1 0 2 2 2 0 AAA domain RNA12 PF10443.9 KDO35547.1 - 0.21 10.3 5.2 0.14 10.9 2.8 1.8 2 0 0 2 2 2 0 RNA12 protein DUF913 PF06025.12 KDO35547.1 - 1.5 7.8 7.5 3 6.7 7.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KDO35547.1 - 4 5.5 47.0 7.3 4.7 47.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2151 PF10221.9 KDO35547.1 - 6.9 5.1 8.7 4.5 5.7 6.9 1.6 2 0 0 2 2 2 0 Cell cycle and development regulator Ku_PK_bind PF08785.11 KDO35548.1 - 0.0012 18.9 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Ku C terminal domain like LegC3_N PF18654.1 KDO35548.1 - 0.054 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain PI3_PI4_kinase PF00454.27 KDO35550.1 - 3.6e-34 118.7 0.0 5e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase LLC1 PF14945.6 KDO35551.1 - 0.032 14.8 0.1 0.057 14.0 0.1 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein TFR_dimer PF04253.15 KDO35552.1 - 4.2e-27 94.6 0.0 6.9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KDO35552.1 - 1.1e-09 38.1 0.0 2.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 KDO35552.1 - 0.00023 20.9 0.1 0.00087 19.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 DIOX_N PF14226.6 KDO35553.1 - 4.6e-19 69.3 0.0 7.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO35553.1 - 4.2e-18 65.7 0.0 8.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LEA_4 PF02987.16 KDO35554.1 - 1.5e-07 31.3 18.1 2e-05 24.6 18.1 2.1 1 1 0 1 1 1 1 Late embryogenesis abundant protein DUF883 PF05957.13 KDO35554.1 - 0.00017 22.1 6.4 0.00022 21.7 6.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KDO35554.1 - 0.00041 20.8 7.6 0.00055 20.4 7.6 1.2 1 0 0 1 1 1 1 YtxH-like protein ATP-synt_B PF00430.18 KDO35554.1 - 0.32 11.1 3.8 0.4 10.8 3.8 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MT0933_antitox PF14013.6 KDO35554.1 - 0.91 9.9 14.3 0.14 12.5 6.1 2.2 1 1 1 2 2 2 0 MT0933-like antitoxin protein 2OG-FeII_Oxy PF03171.20 KDO35555.1 - 2.6e-16 59.9 0.1 4.1e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KDO35555.1 - 3.5e-13 50.3 0.0 6.3e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TFIIF_beta PF02270.15 KDO35556.1 - 2.5e-23 82.0 0.4 4.3e-23 81.2 0.4 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KDO35556.1 - 1.2e-09 39.0 0.4 4.1e-09 37.2 0.4 2.1 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TMEM107 PF14995.6 KDO35557.1 - 1e-09 38.9 0.9 1e-09 38.9 0.9 2.0 1 1 1 2 2 2 1 Transmembrane protein CCB1 PF12046.8 KDO35557.1 - 0.096 12.0 1.9 0.13 11.6 1.9 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Phage_connect_1 PF05135.13 KDO35559.1 - 0.037 14.5 0.0 0.092 13.3 0.0 1.7 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein SieB PF14163.6 KDO35562.1 - 0.031 13.8 1.6 0.053 13.0 1.6 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Phage_holin_3_6 PF07332.11 KDO35562.1 - 0.29 11.2 4.2 0.46 10.5 4.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 KDO35562.1 - 2.3 7.8 4.5 4.2 7.0 4.5 1.3 1 0 0 1 1 1 0 Tetraspanin family IQ PF00612.27 KDO35564.1 - 0.00035 20.1 24.5 0.016 14.9 5.3 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif FAD-oxidase_C PF02913.19 KDO35564.1 - 2.1 7.9 5.1 2.7 7.5 5.1 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain PX PF00787.24 KDO35567.1 - 0.0079 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 KDO35568.1 - 1.3e-23 83.7 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35568.1 - 9.2e-23 80.8 0.0 1.1e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Nuf2 PF03800.14 KDO35569.1 - 9.7e-31 106.7 0.0 1.6e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Nuf2 family ATG16 PF08614.11 KDO35569.1 - 1.5e-06 28.6 11.6 2.2e-06 28.0 11.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KDO35569.1 - 0.00083 19.2 5.7 0.0016 18.3 5.7 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CCDC144C PF14915.6 KDO35569.1 - 0.0027 16.9 5.9 0.0033 16.6 4.9 1.6 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region UPF0242 PF06785.11 KDO35569.1 - 0.0096 16.0 3.3 0.015 15.4 3.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 KDO35569.1 - 0.014 15.1 7.9 0.13 12.0 8.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Golgin_A5 PF09787.9 KDO35569.1 - 0.015 14.8 6.2 0.022 14.2 6.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 KDO35569.1 - 0.022 14.8 8.0 0.036 14.1 8.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPAM PF02090.15 KDO35569.1 - 0.025 14.4 7.2 0.034 14.0 3.3 2.3 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DivIC PF04977.15 KDO35569.1 - 0.032 14.0 8.9 2.4 8.0 0.1 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF724 PF05266.14 KDO35569.1 - 0.057 13.2 4.3 0.093 12.5 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSC22 PF01166.18 KDO35569.1 - 0.059 13.7 3.6 1.3 9.4 0.1 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family YscO PF07321.12 KDO35569.1 - 0.073 13.0 10.6 0.12 12.4 10.6 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO RNR_Alpha PF17975.1 KDO35569.1 - 0.082 13.4 1.8 0.8 10.2 0.0 2.4 1 1 1 2 2 2 0 Ribonucleotide reductase alpha domain YabA PF06156.13 KDO35569.1 - 0.086 13.5 5.7 1.3 9.8 0.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 KDO35569.1 - 0.1 12.8 7.8 0.27 11.5 7.8 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KDO35569.1 - 0.11 11.3 9.5 1.4 7.7 6.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 KDO35569.1 - 0.11 12.6 8.2 2.9 8.1 0.2 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 KDO35569.1 - 0.12 12.5 6.5 0.27 11.4 0.0 2.9 1 1 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 KDO35569.1 - 0.12 12.8 10.7 0.16 12.4 1.6 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 KDO35569.1 - 0.15 12.5 10.9 0.32 11.5 0.8 2.8 1 1 2 3 3 3 0 Cell division protein ZapB Ly49 PF08391.10 KDO35569.1 - 0.27 11.6 1.5 0.44 10.9 1.5 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Csm1_N PF18504.1 KDO35569.1 - 0.29 11.5 6.8 0.9 9.9 0.1 2.6 1 1 2 3 3 3 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 KDO35569.1 - 0.31 11.3 5.9 0.79 10.0 6.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KDO35569.1 - 0.43 10.6 2.0 0.7 9.9 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KDO35569.1 - 0.46 11.0 12.3 1.5 9.4 12.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 KDO35569.1 - 0.47 9.5 5.3 0.77 8.8 5.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KDO35569.1 - 0.63 10.1 9.8 0.19 11.8 3.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 KDO35569.1 - 0.66 9.7 11.1 2.1 8.1 8.6 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family COG2 PF06148.11 KDO35569.1 - 1.1 9.4 5.2 11 6.1 2.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 KDO35569.1 - 1.2 9.4 8.6 7.6 6.8 0.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 KDO35569.1 - 1.3 8.2 10.0 1.2 8.4 6.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KDO35569.1 - 3.9 6.8 8.9 9.5 5.5 8.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2935 PF11155.8 KDO35570.1 - 0.014 15.7 0.4 0.015 15.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) His_Phos_1 PF00300.22 KDO35571.1 - 6.2e-35 120.6 0.1 8.3e-28 97.4 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pkinase_Tyr PF07714.17 KDO35572.1 - 3.3e-23 82.3 0.0 4.1e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KDO35572.1 - 2.6e-22 79.4 0.0 3.2e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PAT1 PF09770.9 KDO35573.1 - 0.2 9.9 54.3 0.27 9.5 54.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 KDO35573.1 - 6.7 5.0 4.9 9.8 4.4 4.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 B_lectin PF01453.24 KDO35574.1 - 0.00026 21.5 0.0 0.11 13.0 0.2 2.2 1 1 1 2 2 2 2 D-mannose binding lectin NRDE-2 PF08424.10 KDO35575.1 - 7e-37 127.3 9.1 4.7e-36 124.5 9.1 2.0 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KDO35575.1 - 3.4e-05 24.3 8.0 1.1 10.3 0.4 6.4 5 0 0 5 5 5 2 Tetratricopeptide repeat ERG4_ERG24 PF01222.17 KDO35576.1 - 1.7e-128 429.1 11.3 1.9e-128 428.9 11.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KDO35576.1 - 0.072 12.6 3.3 0.04 13.4 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) PCMT PF01135.19 KDO35577.1 - 3.5e-39 134.7 0.0 4.6e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KDO35577.1 - 3.4e-10 39.9 0.0 8.5e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO35577.1 - 3.5e-09 37.2 0.0 7.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KDO35577.1 - 3.1e-08 33.4 0.1 4.4e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KDO35577.1 - 1.5e-07 32.0 0.0 2.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KDO35577.1 - 1.6e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KDO35577.1 - 5.5e-07 29.6 0.0 8.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KDO35577.1 - 7.2e-07 28.9 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KDO35577.1 - 4.5e-06 26.7 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO35577.1 - 7.7e-06 26.6 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KDO35577.1 - 1.4e-05 25.1 0.1 2.7e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KDO35577.1 - 0.00018 20.5 0.0 0.00093 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_3 PF01596.17 KDO35577.1 - 0.00022 20.5 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase AviRa PF11599.8 KDO35577.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Drc1-Sld2 PF11719.8 KDO35577.1 - 0.0035 17.0 0.0 0.0072 15.9 0.0 1.5 2 0 0 2 2 2 1 DNA replication and checkpoint protein NodS PF05401.11 KDO35577.1 - 0.0043 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KDO35577.1 - 0.0068 15.7 0.2 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TrmK PF04816.12 KDO35577.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Met_10 PF02475.16 KDO35577.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltr_RsmB-F PF01189.17 KDO35577.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F B9-C2 PF07162.11 KDO35578.1 - 2.5e-43 148.2 0.3 3.3e-43 147.8 0.3 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4551 PF15087.6 KDO35578.1 - 3.4 6.4 10.6 4.7 5.9 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Thioredoxin PF00085.20 KDO35579.1 - 3e-23 81.8 0.1 3.6e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KDO35579.1 - 1.2e-05 25.7 0.1 0.00013 22.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KDO35579.1 - 0.0003 21.0 0.1 0.017 15.5 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Phosducin PF02114.16 KDO35579.1 - 0.00081 18.4 0.0 0.00096 18.2 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.6 KDO35579.1 - 0.016 15.2 0.0 0.033 14.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 KDO35579.1 - 0.023 14.5 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 KDO35579.1 - 0.027 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin GIT_SHD PF08518.11 KDO35579.1 - 0.11 12.1 1.4 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT ArfGap PF01412.18 KDO35579.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CRT-like PF08627.10 KDO35580.1 - 3.9e-66 223.3 13.7 4.7e-66 223.0 13.7 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 KDO35580.1 - 7.7e-07 28.9 12.8 1.2e-06 28.3 0.6 2.6 2 1 1 3 3 3 3 Solute carrier family 35 UAA PF08449.11 KDO35580.1 - 0.00052 19.3 1.9 0.00052 19.3 1.9 1.7 2 0 0 2 2 2 1 UAA transporter family UPF0060 PF02694.15 KDO35580.1 - 0.029 14.6 2.0 0.31 11.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family CRT-like PF08627.10 KDO35581.1 - 9.4e-62 208.9 15.7 1.1e-61 208.7 15.7 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 KDO35581.1 - 1.4e-05 24.8 2.6 1.4e-05 24.8 2.6 2.2 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 KDO35581.1 - 0.027 14.6 0.3 0.027 14.6 0.3 3.9 3 2 1 4 4 4 0 EamA-like transporter family CRT-like PF08627.10 KDO35582.1 - 3.1e-63 213.7 12.1 3.7e-63 213.5 12.1 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 KDO35582.1 - 9e-08 32.0 0.4 9e-08 32.0 0.4 2.5 2 1 0 2 2 2 2 Solute carrier family 35 PUNUT PF16913.5 KDO35582.1 - 0.15 11.2 6.7 1.4 8.1 0.8 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Ribosomal_L22 PF00237.19 KDO35583.1 - 1.8e-25 89.2 0.2 2.9e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e BP28CT PF08146.12 KDO35584.1 - 2.6e-34 118.3 0.0 1.6e-33 115.8 0.0 2.5 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KDO35584.1 - 8e-18 64.9 0.1 8e-18 64.9 0.1 6.9 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 ParcG PF10274.9 KDO35584.1 - 0.12 12.5 9.9 26 4.9 0.0 5.8 6 0 0 6 6 6 0 Parkin co-regulated protein HEAT PF02985.22 KDO35584.1 - 0.2 12.0 11.5 51 4.5 0.5 7.6 7 0 0 7 7 7 0 HEAT repeat CRAL_TRIO_2 PF13716.6 KDO35584.1 - 0.71 10.0 2.9 30 4.7 0.2 3.1 3 0 0 3 3 3 0 Divergent CRAL/TRIO domain NYD-SP28 PF14772.6 KDO35585.1 - 2.7e-28 98.0 12.5 2.7e-28 98.0 12.5 6.3 4 1 3 8 8 8 1 Sperm tail NYD-SP28_assoc PF14775.6 KDO35585.1 - 7.1e-18 64.5 0.2 7.1e-18 64.5 0.2 5.2 3 1 2 5 5 5 1 Sperm tail C-terminal domain Tai4 PF16695.5 KDO35585.1 - 1.6 9.3 6.1 1.4 9.5 1.1 2.8 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein Pro_isomerase PF00160.21 KDO35586.1 - 2.2e-49 167.8 0.1 2.5e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ParBc PF02195.18 KDO35587.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain CRT-like PF08627.10 KDO35588.1 - 8.8e-62 209.0 8.8 1e-61 208.8 8.8 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 KDO35588.1 - 7.9e-07 28.9 0.1 7.9e-07 28.9 0.1 2.1 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 KDO35589.1 - 1.1e-62 211.9 12.4 1.3e-62 211.7 12.4 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 KDO35589.1 - 2.6e-07 30.4 9.0 4.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 KDO35589.1 - 0.0017 17.6 1.9 0.013 14.7 0.3 2.3 2 1 0 2 2 2 1 Nucleotide-sugar transporter MFS_MOT1 PF16983.5 KDO35589.1 - 1.2 9.5 7.3 0.5 10.8 2.1 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily TALPID3 PF15324.6 KDO35590.1 - 0.14 9.8 5.8 0.17 9.6 5.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Keratin_2_tail PF16210.5 KDO35590.1 - 1.8 8.8 16.3 2.4 8.4 16.3 1.1 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail ERO1 PF04137.15 KDO35591.1 - 2.3e-115 385.6 0.1 3e-115 385.2 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HSF_DNA-bind PF00447.17 KDO35592.1 - 2e-24 86.0 0.5 3.5e-24 85.2 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 KDO35593.1 - 1.5e-25 89.7 0.6 2.5e-25 88.9 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3123 PF11321.8 KDO35593.1 - 9.7 6.9 6.6 1 10.1 1.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3123) HSF_DNA-bind PF00447.17 KDO35594.1 - 2.9e-25 88.7 0.1 4.5e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding WD40 PF00400.32 KDO35595.1 - 1.1e-69 228.6 14.9 2e-09 37.9 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35595.1 - 2.2e-20 72.8 1.6 0.00016 21.9 0.0 7.0 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KDO35595.1 - 5.7e-11 42.3 5.9 0.00018 21.0 0.4 5.4 4 2 0 5 5 5 4 WD40-like domain eIF2A PF08662.11 KDO35595.1 - 3.7e-10 40.0 7.9 0.0045 16.9 0.0 3.5 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KDO35595.1 - 9.2e-10 38.0 3.6 0.022 13.7 0.0 5.0 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KDO35595.1 - 1.5e-06 27.2 7.0 0.37 9.4 0.0 5.3 2 2 4 6 6 6 3 Nucleoporin Nup120/160 DUF5570 PF17731.1 KDO35595.1 - 5.8e-05 23.2 4.8 0.087 12.9 0.0 4.7 1 1 4 5 5 4 1 Family of unknown function (DUF5570) WD40_3 PF15911.5 KDO35595.1 - 0.0048 16.9 0.0 9.4 6.3 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Frtz PF11768.8 KDO35595.1 - 0.033 12.5 0.1 41 2.3 0.0 4.2 2 1 3 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz PKD PF00801.20 KDO35595.1 - 0.058 13.3 0.6 48 3.9 0.1 3.4 3 0 0 3 3 3 0 PKD domain zf-RING_2 PF13639.6 KDO35596.1 - 9.4e-12 45.1 3.5 1.6e-11 44.4 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain Tom7 PF08038.12 KDO35596.1 - 5.2e-11 42.0 0.1 1e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 TOM7 family zf-rbx1 PF12678.7 KDO35596.1 - 4.7e-08 33.2 4.7 9.4e-08 32.2 4.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KDO35596.1 - 9.6e-08 31.9 1.4 1.5e-07 31.3 0.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KDO35596.1 - 4.9e-07 29.5 3.3 1.5e-06 28.0 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KDO35596.1 - 5.8e-07 29.3 3.4 9.3e-07 28.6 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KDO35596.1 - 1.6e-06 28.0 1.7 2.7e-06 27.2 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KDO35596.1 - 4.5e-06 26.4 2.3 8.9e-06 25.5 2.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KDO35596.1 - 4.7e-06 26.2 0.9 4.7e-06 26.2 0.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 KDO35596.1 - 0.0018 18.1 3.0 0.0054 16.6 3.0 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KDO35596.1 - 0.0022 18.0 1.4 0.0043 17.1 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KDO35596.1 - 0.044 13.4 4.3 0.11 12.2 4.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KDO35596.1 - 0.048 13.5 0.3 0.089 12.6 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KDO35596.1 - 0.11 12.8 1.3 0.23 11.8 1.3 1.5 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KDO35596.1 - 0.2 11.8 3.4 0.59 10.3 3.4 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KDO35596.1 - 0.26 11.4 2.8 0.26 11.3 1.1 1.9 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 KDO35596.1 - 0.46 10.7 3.0 1.6 9.0 3.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KDO35596.1 - 0.79 9.9 5.2 9.6 6.5 5.7 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SR-25 PF10500.9 KDO35597.1 - 0.18 11.4 2.9 0.46 10.1 2.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4074 PF13293.6 KDO35598.1 - 0.1 12.9 0.9 1.3 9.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4074) His_biosynth PF00977.21 KDO35599.1 - 1.2e-43 149.3 0.1 6e-43 146.9 0.1 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KDO35599.1 - 1.2e-20 74.2 0.0 1.8e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KDO35599.1 - 2.4e-06 27.5 0.0 1.6e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KDO35599.1 - 2e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KDO35599.1 - 0.00054 19.8 0.1 0.0024 17.7 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 DUF2754 PF10953.8 KDO35600.1 - 2.9 8.2 5.8 0.49 10.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) SHIPPO-rpt PF07004.12 KDO35601.1 - 0.0058 17.5 0.1 2.7 9.1 0.0 3.0 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat zf-C3HC4_3 PF13920.6 KDO35602.1 - 7.8e-11 41.7 16.1 1.7e-10 40.6 16.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KDO35602.1 - 1.8e-06 27.7 14.8 3.6e-06 26.7 14.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 K-box PF01486.17 KDO35602.1 - 0.00032 20.8 14.5 0.00032 20.8 14.5 2.5 1 1 1 2 2 2 1 K-box region RRM_1 PF00076.22 KDO35602.1 - 0.0029 17.4 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gti1_Pac2 PF09729.9 KDO35602.1 - 0.12 12.5 7.9 0.03 14.4 3.6 2.3 2 1 0 2 2 2 0 Gti1/Pac2 family Metal_resist PF13801.6 KDO35602.1 - 0.72 10.0 16.4 0.13 12.4 6.4 2.6 1 1 1 2 2 2 0 Heavy-metal resistance FAM220 PF15487.6 KDO35602.1 - 0.77 9.3 6.6 0.26 10.9 0.8 2.5 2 0 0 2 2 2 0 FAM220 family DUF3246 PF11596.8 KDO35602.1 - 4.7 6.6 9.9 5.1 6.4 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CREPT PF16566.5 KDO35602.1 - 9.4 6.4 16.3 1.8 8.7 9.1 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Myosin_head PF00063.21 KDO35603.1 - 1.9e-167 558.5 0.0 1.4e-166 555.6 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) KLRAQ PF10205.9 KDO35603.1 - 0.0019 18.4 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein AAA_22 PF13401.6 KDO35603.1 - 0.0081 16.4 0.0 0.037 14.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KDO35603.1 - 0.035 13.2 0.0 0.1 11.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KDO35603.1 - 0.63 10.4 0.0 0.63 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 KDO35603.1 - 4.9 7.7 5.6 17 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain PI3_PI4_kinase PF00454.27 KDO35605.1 - 4.3e-48 164.3 0.0 7.8e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KDO35605.1 - 2.9e-41 140.9 0.6 1e-40 139.1 0.0 2.1 3 0 0 3 3 3 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KDO35605.1 - 1.3e-09 38.1 0.0 6e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KDO35605.1 - 0.00041 19.8 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) zf-H2C2_2 PF13465.6 KDO35606.1 - 2.9e-16 59.1 38.0 1.1e-06 28.7 1.8 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KDO35606.1 - 1.2e-14 53.8 34.8 1e-05 25.7 0.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO35606.1 - 4e-11 42.8 33.3 0.00015 22.3 0.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KDO35606.1 - 8.2e-05 22.5 0.3 8.2e-05 22.5 0.3 5.0 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2HE PF16278.5 KDO35606.1 - 0.0036 17.7 0.7 0.0036 17.7 0.7 2.3 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KDO35606.1 - 0.28 11.5 0.0 0.28 11.5 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO35606.1 - 0.31 11.5 0.1 0.31 11.5 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KDO35606.1 - 0.32 11.7 14.1 2 9.1 0.1 4.0 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KDO35606.1 - 0.48 10.5 9.4 2.7 8.1 0.9 2.6 1 1 1 2 2 2 0 Aberrant zinc-finger Endonuclease_7 PF02945.15 KDO35606.1 - 3.7 7.5 15.3 0.15 12.0 1.4 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII zf-H2C2_2 PF13465.6 KDO35607.1 - 3.6e-16 58.7 37.5 1.3e-06 28.6 1.8 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KDO35607.1 - 1.7e-14 53.4 34.8 1.1e-05 25.6 0.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KDO35607.1 - 5.4e-11 42.4 33.3 0.00017 22.2 0.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KDO35607.1 - 9e-05 22.4 0.3 9e-05 22.4 0.3 5.1 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2HE PF16278.5 KDO35607.1 - 0.004 17.6 0.7 0.004 17.6 0.7 2.3 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 KDO35607.1 - 0.19 11.9 7.5 2.7 8.1 0.6 2.5 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KDO35607.1 - 0.31 11.4 0.0 0.31 11.4 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KDO35607.1 - 0.34 11.4 0.1 0.34 11.4 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KDO35607.1 - 1.2 9.9 15.0 2.1 9.0 0.1 4.1 2 1 2 4 4 4 0 FOXP coiled-coil domain CCAP PF11105.8 KDO35607.1 - 9.7 6.2 8.1 2.2 8.2 3.0 2.2 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a DBR1 PF05011.13 KDO35608.1 - 1.7e-26 93.3 0.0 2.4e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KDO35608.1 - 4.6e-10 40.3 0.7 6.6e-10 39.8 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KDO35608.1 - 0.073 13.3 0.3 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain UCH_1 PF13423.6 KDO35609.1 - 3.3e-33 115.6 0.1 1.1e-24 87.7 0.1 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KDO35609.1 - 0.012 15.1 0.1 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 KDO35609.1 - 0.018 15.3 0.0 13 6.2 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RcnB PF11776.8 KDO35609.1 - 0.025 14.6 0.1 0.077 13.1 0.1 1.9 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Frtz PF11768.8 KDO35609.1 - 0.13 10.5 0.0 3.3 5.9 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2807 PF10988.8 KDO35610.1 - 4.7e-13 49.3 7.4 5.7e-08 32.8 2.7 2.3 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain Pro_isomerase PF00160.21 KDO35611.1 - 9.4e-39 133.2 0.1 1.2e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 KDO35612.1 - 6.4e-35 120.8 0.0 8.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1084 PF06454.11 KDO35613.1 - 0.16 11.3 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Bromodomain PF00439.25 KDO35614.1 - 3.6e-22 78.2 0.4 1.1e-21 76.7 0.2 1.9 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 KDO35614.1 - 6.4e-11 42.5 0.1 1.3e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KDO35614.1 - 3.6e-10 39.9 0.1 1.1e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KDO35614.1 - 2e-06 28.1 0.4 3.9e-06 27.2 0.4 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KDO35614.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein UPF0054 PF02130.17 KDO35614.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Fucose_iso_N2 PF07882.12 KDO35614.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Ribosomal_60s PF00428.19 KDO35615.1 - 4.1e-17 62.5 5.6 5.1e-17 62.2 5.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein eIF3_subunit PF08597.10 KDO35615.1 - 0.015 15.3 0.6 0.022 14.7 0.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RecR PF02132.15 KDO35617.1 - 0.4 10.3 5.7 12 5.5 0.4 3.7 3 0 0 3 3 3 0 RecR protein bZIP_2 PF07716.15 KDO35618.1 - 2.7e-07 30.6 23.1 5e-06 26.5 17.0 2.8 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KDO35618.1 - 1.8e-06 27.9 16.1 1.8e-06 27.9 16.1 2.4 2 0 0 2 2 2 1 bZIP transcription factor DUF601 PF04642.12 KDO35618.1 - 0.00031 20.4 1.0 0.00044 19.8 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF601 YabA PF06156.13 KDO35618.1 - 5 7.8 8.5 1.9 9.2 0.5 2.6 2 1 0 2 2 2 0 Initiation control protein YabA RWP-RK PF02042.15 KDO35620.1 - 0.00061 19.7 1.0 0.31 11.1 0.1 2.2 1 1 1 2 2 2 2 RWP-RK domain TPR_10 PF13374.6 KDO35621.1 - 0.052 13.4 5.0 4.4 7.3 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KDO35621.1 - 1.1 9.7 12.5 23 5.4 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat START PF01852.19 KDO35622.1 - 4.9e-14 52.2 0.1 1e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 KDO35622.1 - 0.01 16.1 4.2 0.018 15.3 4.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KDO35622.1 - 0.12 12.5 7.9 0.25 11.5 7.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-piccolo PF05715.13 KDO35622.1 - 0.32 11.2 5.4 0.33 11.1 3.3 2.1 2 0 0 2 2 2 0 Piccolo Zn-finger AMP-binding PF00501.28 KDO35623.1 - 9.2e-97 324.3 0.2 1.2e-96 324.0 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KDO35623.1 - 6.5e-23 81.5 0.6 1.6e-22 80.2 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KDO35623.1 - 1.7e-17 63.1 1.7 4e-17 61.9 1.7 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 KDO35624.1 - 1.1e-17 64.1 10.8 2.5e-06 28.1 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35624.1 - 0.0012 19.1 0.1 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KDO35624.1 - 0.009 14.8 0.1 0.11 11.2 0.0 2.2 1 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 KDO35624.1 - 0.025 13.2 1.0 0.2 10.2 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 F-box-like PF12937.7 KDO35624.1 - 0.043 13.7 0.8 0.089 12.7 0.1 1.9 2 0 0 2 2 2 0 F-box-like PLDc PF00614.22 KDO35626.1 - 2.1e-06 27.7 0.1 5.1e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 KDO35626.1 - 0.00014 21.8 0.0 0.0071 16.2 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain PX PF00787.24 KDO35626.1 - 0.042 13.8 0.2 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 PX domain PH PF00169.29 KDO35626.1 - 0.12 12.9 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 PH domain DUF997 PF06196.12 KDO35626.1 - 0.83 9.7 5.2 4.6 7.3 5.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF997) DUF2207 PF09972.9 KDO35626.1 - 4.2 6.0 4.5 3 6.5 2.6 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2039 PF10217.9 KDO35627.1 - 8.6e-31 106.1 12.3 8.6e-31 106.1 12.3 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 KDO35627.1 - 0.0042 17.6 13.0 0.0042 17.6 13.0 2.0 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 KDO35627.1 - 0.017 15.1 11.7 0.028 14.4 11.7 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF3381 PF11861.8 KDO35627.1 - 0.032 14.1 9.4 0.048 13.5 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) ADK_lid PF05191.14 KDO35627.1 - 1.3 9.0 8.0 13 5.8 0.0 3.2 2 1 1 3 3 3 0 Adenylate kinase, active site lid NUDIX PF00293.28 KDO35628.1 - 7.1e-09 35.8 0.2 1.7e-07 31.3 0.2 2.2 1 1 0 1 1 1 1 NUDIX domain RyR PF02026.16 KDO35630.1 - 4.2e-61 203.1 0.0 1.5e-29 102.0 0.0 2.7 2 0 0 2 2 2 2 RyR domain PKD_channel PF08016.12 KDO35630.1 - 1.6e-44 152.3 2.9 2.6e-44 151.6 2.9 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KDO35630.1 - 4.4e-11 42.5 14.3 4.4e-11 42.5 14.3 1.7 2 0 0 2 2 2 1 Ion transport protein Ni_hydr_CYTB PF01292.20 KDO35630.1 - 0.65 9.6 5.0 1.1 8.8 0.5 2.6 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 TAL_FSA PF00923.19 KDO35631.1 - 4.5e-102 341.3 0.1 5.1e-102 341.1 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 KDO35632.1 - 1.7e-51 175.1 0.0 2.4e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35632.1 - 6.6e-51 173.1 0.0 9.5e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KDO35633.1 - 2.5e-28 99.6 0.8 3.2e-28 99.3 0.8 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KDO35633.1 - 0.0065 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KDO35633.1 - 0.05 13.0 0.0 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyoxalase PF00903.25 KDO35635.1 - 4.2e-20 72.2 0.0 1.2e-10 41.7 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KDO35635.1 - 1.4e-07 32.3 0.1 9.8e-05 23.1 0.0 3.1 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KDO35635.1 - 1.7e-07 31.5 0.0 1.4e-05 25.4 0.0 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.8 KDO35635.1 - 0.1 12.4 0.0 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Kinesin PF00225.23 KDO35636.1 - 7.4e-97 324.3 0.0 3.5e-96 322.0 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO35636.1 - 2.9e-26 92.2 0.0 1.1e-25 90.3 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding IMPDH PF00478.25 KDO35637.1 - 3.3e-132 440.7 4.6 3.8e-132 440.5 4.6 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KDO35637.1 - 4e-16 59.2 0.1 6.1e-09 36.2 0.1 3.6 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 KDO35637.1 - 8.4e-10 38.5 2.0 5e-07 29.4 2.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KDO35637.1 - 5.9e-07 28.8 1.4 2.7e-06 26.6 1.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KDO35637.1 - 3.9e-05 23.2 3.1 0.0004 19.9 2.3 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KDO35637.1 - 0.00092 18.6 0.1 0.0022 17.3 0.1 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KDO35637.1 - 0.014 14.6 0.8 0.099 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.17 KDO35637.1 - 0.045 12.9 1.8 0.3 10.1 0.1 2.6 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KDO35637.1 - 0.13 11.5 3.7 0.081 12.1 0.5 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KDO35637.1 - 0.16 11.4 0.6 0.62 9.5 0.2 2.2 1 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator AIM24 PF01987.17 KDO35638.1 - 1.1e-62 211.5 1.1 1.4e-62 211.1 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4073 PF13285.6 KDO35638.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) WW PF00397.26 KDO35638.1 - 0.13 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 WW domain Disintegrin PF00200.23 KDO35639.1 - 8.2e-12 45.8 43.9 0.00051 20.8 12.5 5.2 3 3 1 4 4 4 4 Disintegrin Disintegrin PF00200.23 KDO35640.1 - 8.5e-22 77.7 81.0 1.6e-05 25.6 11.9 7.9 5 4 3 8 8 8 6 Disintegrin PH PF00169.29 KDO35641.1 - 3.5e-20 72.5 0.0 1.5e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 PH domain VPS9 PF02204.18 KDO35641.1 - 6.3e-11 42.4 0.5 1.3e-10 41.4 0.5 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PDZ PF00595.24 KDO35641.1 - 1.1e-05 25.6 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 KDO35641.1 - 7.3e-05 23.0 0.2 0.42 10.9 0.2 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PDZ_6 PF17820.1 KDO35641.1 - 0.0003 20.6 0.2 0.00071 19.4 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO35641.1 - 0.016 15.5 0.1 0.036 14.4 0.1 1.6 1 0 0 1 1 1 0 PDZ domain PH_3 PF14593.6 KDO35641.1 - 0.017 15.2 0.0 0.37 10.9 0.0 2.7 3 0 0 3 3 3 0 PH domain GDP_Man_Dehyd PF16363.5 KDO35642.1 - 1.1e-147 491.8 0.0 1.2e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KDO35642.1 - 9.4e-71 238.1 0.0 1.2e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KDO35642.1 - 0.0002 20.6 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KDO35642.1 - 0.056 12.6 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 KDO35642.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Pribosyltran PF00156.27 KDO35643.1 - 1e-20 73.8 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KDO35643.1 - 0.0069 15.9 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 KDO35643.1 - 0.023 14.1 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MTCP1 PF08991.10 KDO35644.1 - 8.9e-10 38.7 11.6 2.8e-09 37.1 11.6 1.8 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type NAM-associated PF14303.6 KDO35644.1 - 0.00025 21.8 3.4 0.00059 20.6 3.4 1.6 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain YqfQ PF14181.6 KDO35644.1 - 2.4 8.3 4.8 5.3 7.2 4.8 1.5 1 0 0 1 1 1 0 YqfQ-like protein COPI_assoc PF08507.10 KDO35646.1 - 2.8e-11 43.6 9.4 3.6e-11 43.2 9.4 1.1 1 0 0 1 1 1 1 COPI associated protein DUF373 PF04123.13 KDO35646.1 - 0.066 12.6 3.9 0.086 12.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1211 PF06736.11 KDO35646.1 - 0.084 13.3 2.7 0.16 12.4 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF2985 PF11204.8 KDO35646.1 - 0.21 11.7 9.2 2.4 8.4 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) UQ_con PF00179.26 KDO35647.1 - 1.5e-15 57.1 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KDO35647.1 - 0.0054 16.6 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KDO35647.1 - 0.057 13.7 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain LTD PF00932.19 KDO35648.1 - 7.6e-10 39.1 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain CTP_transf_like PF01467.26 KDO35649.1 - 6.3e-08 32.9 0.0 7.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Methyltransf_16 PF10294.9 KDO35650.1 - 5.6e-24 84.8 0.0 8.2e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KDO35650.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KDO35650.1 - 0.0002 21.2 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO35650.1 - 0.016 15.9 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KDO35650.1 - 0.022 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KDO35650.1 - 0.047 13.4 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KDO35650.1 - 0.087 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KDO35650.1 - 0.13 13.0 0.0 0.25 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain YjgF_endoribonc PF14588.6 KDO35651.1 - 3.7e-25 88.8 0.0 4.2e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 KDO35651.1 - 2.9e-17 62.8 0.1 6.9e-17 61.6 0.1 1.5 1 1 0 1 1 1 1 Endoribonuclease L-PSP DUF755 PF05501.11 KDO35652.1 - 0.098 12.9 2.8 0.45 10.8 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF755) ATPase PF06745.13 KDO35652.1 - 0.28 10.5 4.0 1.9 7.8 0.1 3.2 3 0 0 3 3 3 0 KaiC DUF1664 PF07889.12 KDO35652.1 - 0.42 10.7 26.7 1.9 8.6 1.9 6.4 6 1 1 7 7 7 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KDO35652.1 - 1.6 8.6 5.5 6 6.8 0.6 3.8 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD Prefoldin_3 PF13758.6 KDO35652.1 - 4.5 7.4 8.0 5.5 7.1 0.0 4.3 3 2 0 4 4 4 0 Prefoldin subunit DUF2205 PF10224.9 KDO35653.1 - 0.0014 18.6 0.6 0.0014 18.6 0.6 5.9 7 2 0 7 7 7 1 Short coiled-coil protein DUF5082 PF16888.5 KDO35653.1 - 0.045 14.0 0.2 0.045 14.0 0.2 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 KDO35653.1 - 0.16 12.3 0.2 0.16 12.3 0.2 6.4 7 0 0 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5320 PF17253.2 KDO35653.1 - 0.61 11.2 4.9 7.8 7.6 0.3 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Tup_N PF08581.10 KDO35653.1 - 1.7 9.0 11.9 18 5.7 0.1 5.1 5 0 0 5 5 5 0 Tup N-terminal AKNA PF12443.8 KDO35653.1 - 3 8.6 10.6 4.9 7.9 0.6 4.0 3 1 1 4 4 4 0 AT-hook-containing transcription factor DUF1664 PF07889.12 KDO35653.1 - 7.9 6.5 21.5 13 5.8 0.1 6.2 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) Ceramidase_alk PF04734.13 KDO35654.1 - 1.6e-128 429.5 0.0 1.5e-127 426.4 0.0 1.9 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KDO35654.1 - 9.7e-42 142.7 0.8 2.4e-41 141.4 0.1 1.9 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal CDC27 PF09507.10 KDO35656.1 - 0.066 12.6 2.4 0.086 12.2 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BTHB PF18410.1 KDO35657.1 - 2.6e-06 27.1 0.1 0.00027 20.7 0.0 2.8 1 1 1 2 2 2 2 Basic tilted helix bundle domain MAPEG PF01124.18 KDO35658.1 - 2.2e-17 63.2 0.0 3.3e-17 62.6 0.0 1.3 1 1 0 1 1 1 1 MAPEG family CBP4 PF07960.11 KDO35658.1 - 0.056 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 CBP4 ECH_1 PF00378.20 KDO35659.1 - 1.7e-40 139.0 0.0 2.2e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KDO35659.1 - 3.3e-21 76.1 0.0 4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SNO PF01174.19 KDO35660.1 - 1.5e-52 178.2 0.0 1.8e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KDO35660.1 - 3.4e-09 36.6 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KDO35660.1 - 0.00036 20.3 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KDO35660.1 - 0.0022 17.8 0.0 0.02 14.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KDO35660.1 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DEAD PF00270.29 KDO35662.1 - 5.3e-24 84.9 0.1 1.6e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO35662.1 - 7e-22 77.9 0.1 1.3e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO35662.1 - 0.00067 19.7 0.0 0.0024 17.9 0.0 2.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KDO35662.1 - 0.00082 19.7 0.2 0.0076 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MRP-L28 PF09812.9 KDO35663.1 - 0.00036 20.7 0.1 0.00045 20.4 0.1 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 Kv2channel PF03521.14 KDO35663.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel CG-1 PF03859.16 KDO35664.1 - 1.2e-28 99.2 0.2 9.1e-28 96.4 0.0 2.2 2 0 0 2 2 2 1 CG-1 domain Ank_5 PF13857.6 KDO35664.1 - 9.9e-18 64.0 2.9 4e-12 46.1 0.4 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) IQ PF00612.27 KDO35664.1 - 6.9e-12 44.1 7.0 0.006 16.3 0.1 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ank_2 PF12796.7 KDO35664.1 - 5e-11 43.0 0.2 1.2e-10 41.8 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KDO35664.1 - 1.9e-07 30.8 0.8 0.00024 21.3 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KDO35664.1 - 2.3e-06 28.0 0.6 1.2e-05 25.8 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KDO35664.1 - 1.1e-05 25.6 7.0 3.4e-05 24.1 0.2 3.3 4 0 0 4 4 4 1 Ankyrin repeat TIG PF01833.24 KDO35664.1 - 0.024 14.7 0.1 0.21 11.7 0.1 2.2 1 1 0 1 1 1 0 IPT/TIG domain DEP PF00610.21 KDO35665.1 - 2.3e-19 69.2 0.0 9e-12 44.9 0.0 2.5 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.32 KDO35666.1 - 5.9e-09 36.4 3.5 0.13 13.2 0.0 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat DUF3742 PF12553.8 KDO35667.1 - 0.063 13.4 0.1 0.063 13.4 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DUF2304 PF10066.9 KDO35667.1 - 1.9 8.8 8.4 6.3 7.1 8.4 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) YjeF_N PF03853.15 KDO35668.1 - 1e-37 129.6 0.0 1.3e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus WD40 PF00400.32 KDO35669.1 - 2e-28 98.1 15.8 0.0089 16.9 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35669.1 - 2.3e-08 34.2 0.1 1 9.7 0.0 6.7 3 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KDO35669.1 - 7.8e-07 29.4 1.7 0.15 12.6 0.0 6.0 6 0 0 6 6 6 2 PQQ-like domain WD40_like PF17005.5 KDO35669.1 - 0.00013 21.4 0.0 0.0049 16.2 0.0 3.1 3 1 1 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KDO35669.1 - 0.021 13.6 0.7 3.4 6.3 0.0 3.2 2 2 0 2 2 2 0 Nup133 N terminal like DUF2076 PF09849.9 KDO35670.1 - 0.24 11.4 7.0 0.034 14.2 2.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Arv1 PF04161.13 KDO35672.1 - 6.6e-44 150.6 8.2 8.3e-44 150.3 8.2 1.1 1 0 0 1 1 1 1 Arv1-like family Acyl-CoA_dh_M PF02770.19 KDO35673.1 - 2.2e-12 47.0 0.0 5.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KDO35673.1 - 1.8e-09 38.2 0.0 3.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Methyltransf_28 PF02636.17 KDO35674.1 - 2.1e-34 119.3 0.0 3.6e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KDO35674.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KDO35674.1 - 0.0065 17.2 0.0 0.015 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO35674.1 - 0.0097 16.6 0.0 0.089 13.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain PPR_2 PF13041.6 KDO35675.1 - 4.1e-06 26.9 3.6 3.5e-05 23.9 0.5 2.8 2 1 1 3 3 3 1 PPR repeat family MRP-S27 PF10037.9 KDO35675.1 - 0.0017 17.3 1.4 0.0027 16.7 1.4 1.5 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_3 PF13812.6 KDO35675.1 - 0.0086 16.1 4.0 0.034 14.2 0.4 2.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KDO35675.1 - 0.07 12.5 1.1 0.79 9.0 0.3 2.1 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KDO35675.1 - 0.31 11.4 1.6 38 4.8 0.1 3.3 4 0 0 4 4 4 0 PPR repeat TPR_15 PF13429.6 KDO35676.1 - 0.0066 15.7 1.1 0.0091 15.2 0.7 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat PPR PF01535.20 KDO35676.1 - 0.0097 16.1 0.0 0.093 13.0 0.0 2.7 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.6 KDO35676.1 - 0.01 16.6 0.7 0.051 14.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 KDO35676.1 - 0.017 15.2 0.1 0.4 10.8 0.0 3.1 2 1 2 4 4 4 0 Pentatricopeptide repeat domain MRP-S27 PF10037.9 KDO35676.1 - 0.026 13.4 1.5 0.16 10.8 0.0 2.4 1 1 2 3 3 3 0 Mitochondrial 28S ribosomal protein S27 AAA_assoc_2 PF16193.5 KDO35676.1 - 0.063 13.6 1.3 0.11 12.9 0.2 1.9 2 1 0 2 2 2 0 AAA C-terminal domain PPR_2 PF13041.6 KDO35676.1 - 0.084 13.1 0.0 1.9 8.7 0.0 2.8 2 1 1 3 3 3 0 PPR repeat family PPR_long PF17177.4 KDO35676.1 - 0.11 11.8 3.5 0.31 10.4 2.3 2.2 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 KDO35676.1 - 0.12 12.4 0.2 0.8 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 KDO35676.1 - 0.13 12.3 0.4 0.92 9.6 0.1 2.0 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein SIR2 PF02146.17 KDO35677.1 - 5.8e-21 75.2 0.2 8.3e-14 51.9 0.0 2.3 1 1 1 2 2 2 2 Sir2 family Stealth_CR2 PF11380.8 KDO35678.1 - 1e-32 112.5 0.0 1.7e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KDO35678.1 - 2.7e-12 46.2 0.6 5e-12 45.3 0.6 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 KDO35679.1 - 8.2e-44 148.2 0.1 9.4e-42 141.6 0.0 3.1 3 0 0 3 3 3 1 Stealth protein CR2, conserved region 2 Methyltransf_16 PF10294.9 KDO35679.1 - 1.3e-23 83.6 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Stealth_CR3 PF17102.5 KDO35679.1 - 5.7e-17 61.4 2.9 5.7e-17 61.4 2.9 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KDO35679.1 - 1.2e-12 48.1 23.5 2e-06 28.1 7.0 2.8 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 KDO35679.1 - 1.9e-11 43.5 0.6 3.6e-11 42.6 0.6 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 KDO35679.1 - 6.5e-10 38.7 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Methyltransf_23 PF13489.6 KDO35679.1 - 0.0037 17.1 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PAS_6 PF08348.11 KDO35679.1 - 0.084 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 YheO-like PAS domain Romo1 PF10247.9 KDO35680.1 - 5.1 7.5 9.2 0.71 10.3 4.1 2.1 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 SAM_1 PF00536.30 KDO35681.1 - 1.1e-08 35.4 0.4 1e-07 32.3 0.1 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KDO35681.1 - 2.8e-07 30.5 0.4 1.3e-06 28.4 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LSM PF01423.22 KDO35682.1 - 1.8e-17 62.7 0.5 3.6e-17 61.8 0.5 1.4 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KDO35682.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Hfq protein tRNA_lig_kinase PF08303.11 KDO35682.1 - 0.11 12.5 1.5 0.93 9.6 1.1 1.9 1 1 1 2 2 2 0 tRNA ligase kinase domain WD40 PF00400.32 KDO35683.1 - 8.2e-32 108.8 11.5 1.4e-06 28.9 0.2 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 KDO35683.1 - 3.9e-28 97.6 14.4 6.6e-28 96.8 14.4 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KDO35683.1 - 2.7e-08 34.0 0.0 0.013 15.8 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KDO35683.1 - 8.4e-06 25.8 0.0 0.0012 18.8 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KDO35683.1 - 0.01 14.8 0.1 0.52 9.2 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SMBP PF16785.5 KDO35683.1 - 0.084 13.1 0.8 1.3 9.3 0.8 2.3 2 0 0 2 2 2 0 Small metal-binding protein Spc24 PF08286.11 KDO35685.1 - 0.15 12.3 1.9 0.2 11.9 1.9 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KDO35685.1 - 0.3 11.1 6.4 2 8.4 0.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 KDO35685.1 - 0.82 10.2 9.0 1 9.9 9.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region adh_short PF00106.25 KDO35686.1 - 2.4e-30 105.4 0.2 1.8e-29 102.6 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KDO35686.1 - 1.9e-20 73.4 0.2 2.8e-20 72.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KDO35686.1 - 1.6e-08 34.7 0.8 2.4e-08 34.1 0.8 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KDO35686.1 - 0.00012 22.1 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KDO35686.1 - 0.00091 18.7 0.2 0.0016 17.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KDO35686.1 - 0.0068 16.7 0.2 0.01 16.1 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 KDO35686.1 - 0.027 13.7 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 KDO35686.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_trans_4_4 PF13579.6 KDO35686.1 - 0.13 12.7 0.2 0.13 12.7 0.2 2.0 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain VHS PF00790.19 KDO35687.1 - 2.6e-14 53.3 0.0 3.9e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KDO35687.1 - 0.0033 17.7 0.5 0.014 15.7 0.1 2.1 2 0 0 2 2 2 1 GAT domain Replic_Relax PF13814.6 KDO35687.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Replication-relaxation MORN PF02493.20 KDO35688.1 - 1.4e-15 56.1 12.7 1.8e-05 24.4 1.3 4.2 3 1 0 3 3 3 3 MORN repeat Acid_phosphat_B PF03767.14 KDO35689.1 - 1.9e-27 96.3 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Frataxin_Cyay PF01491.16 KDO35690.1 - 7.6e-30 103.2 0.0 9e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Tyr_Deacylase PF02580.16 KDO35692.1 - 2.5e-46 157.8 0.0 2.8e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase ROK PF00480.20 KDO35697.1 - 2.4e-54 184.8 0.0 3.1e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 KDO35697.1 - 0.0022 17.0 0.9 0.22 10.5 0.5 2.3 2 0 0 2 2 2 2 Glucokinase TPR_2 PF07719.17 KDO35698.1 - 1.1e-13 50.2 0.3 0.00017 21.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KDO35698.1 - 3.2e-12 45.7 0.5 0.0032 17.2 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KDO35698.1 - 6.7e-10 38.4 0.1 0.00041 20.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KDO35698.1 - 3.1e-06 26.8 0.5 0.0021 17.7 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.6 KDO35698.1 - 5.1e-06 26.5 1.1 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KDO35698.1 - 1e-05 25.9 0.7 0.00064 20.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KDO35698.1 - 1.3e-05 25.6 1.4 0.16 12.9 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KDO35698.1 - 2.9e-05 24.1 0.1 0.00064 19.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KDO35698.1 - 0.00041 20.9 1.1 0.46 11.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 KDO35698.1 - 0.0011 18.0 0.2 0.0013 17.8 0.2 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KDO35698.1 - 0.003 16.8 1.3 0.0038 16.5 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KDO35698.1 - 0.094 12.8 0.3 21 5.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sulfate_transp PF00916.20 KDO35699.1 - 1.1e-32 113.2 14.9 1.7e-32 112.7 14.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KDO35699.1 - 2.5e-12 46.7 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KDO35699.1 - 7.6e-09 35.2 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KDO35699.1 - 0.0017 18.6 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain Methyltransf_11 PF08241.12 KDO35701.1 - 1e-09 38.9 0.0 1.9e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KDO35701.1 - 1.2e-09 38.8 0.0 1.9e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KDO35701.1 - 2.1e-09 37.3 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KDO35701.1 - 0.00016 22.3 0.0 0.00031 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain IGPS PF00218.21 KDO35703.1 - 4.3e-76 255.5 0.4 1e-75 254.2 0.2 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KDO35703.1 - 3.3e-40 137.9 0.1 4.9e-35 121.1 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CBM_1 PF00734.18 KDO35704.1 - 1.2e-15 57.2 15.4 3.5e-09 36.5 5.7 3.7 4 0 0 4 4 4 2 Fungal cellulose binding domain DSPc PF00782.20 KDO35705.1 - 9.3e-07 28.7 0.0 1.2e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KDO35705.1 - 2e-06 27.6 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KDO35705.1 - 0.026 14.7 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 KDO35705.1 - 0.071 12.0 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain WD40 PF00400.32 KDO35706.1 - 2.1e-12 47.3 9.8 0.00065 20.5 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat MDH PF02315.16 KDO35706.1 - 0.034 14.2 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit ANAPC4_WD40 PF12894.7 KDO35706.1 - 0.045 14.0 0.5 5.1 7.5 0.1 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain 5-FTHF_cyc-lig PF01812.20 KDO35707.1 - 3.1e-45 154.3 0.0 3.5e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Synaptobrevin PF00957.21 KDO35709.1 - 3.4e-15 55.6 0.3 6.3e-15 54.7 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KDO35709.1 - 1.4e-13 50.6 0.0 2.6e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 KDO35709.1 - 0.013 15.3 0.3 0.042 13.7 0.2 1.9 1 1 0 1 1 1 0 Nsp1-like C-terminal region AAA PF00004.29 KDO35710.1 - 6.3e-71 237.0 0.0 1.1e-37 129.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KDO35710.1 - 1.8e-22 78.9 4.2 1.1e-13 50.8 0.4 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KDO35710.1 - 5.9e-12 46.3 4.8 3.7e-05 24.2 0.9 4.0 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KDO35710.1 - 2.7e-08 33.9 0.1 0.0054 16.7 0.1 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KDO35710.1 - 6.8e-06 26.4 0.4 0.0079 16.5 0.1 3.7 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KDO35710.1 - 3e-05 24.2 0.0 0.055 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KDO35710.1 - 5.7e-05 22.5 0.0 0.073 12.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KDO35710.1 - 9.2e-05 22.6 0.0 0.23 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KDO35710.1 - 0.00013 21.8 0.0 0.37 10.5 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KDO35710.1 - 0.00021 20.9 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 KDO35710.1 - 0.00022 21.2 0.1 0.068 13.1 0.1 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KDO35710.1 - 0.00043 20.3 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KDO35710.1 - 0.00089 19.6 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 KDO35710.1 - 0.0011 18.2 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KDO35710.1 - 0.0057 16.6 0.6 0.23 11.4 0.1 2.6 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.12 KDO35710.1 - 0.0063 15.8 0.0 1.4 8.1 0.1 3.0 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 KDO35710.1 - 0.0065 15.9 0.2 1.1 8.6 0.1 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KDO35710.1 - 0.0065 16.5 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_2 PF02933.17 KDO35710.1 - 0.014 15.1 0.0 0.055 13.3 0.0 2.0 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), domain 2 AAA_29 PF13555.6 KDO35710.1 - 0.015 15.0 0.0 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KDO35710.1 - 0.026 15.0 0.0 7.2 7.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KDO35710.1 - 0.031 14.8 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KDO35710.1 - 0.032 14.6 0.1 0.73 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KDO35710.1 - 0.045 13.5 1.1 4 7.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.11 KDO35710.1 - 0.049 13.5 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KDO35710.1 - 0.065 13.2 0.2 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_11 PF13086.6 KDO35710.1 - 0.083 12.7 0.0 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KDO35710.1 - 0.094 12.3 1.8 20 4.7 0.1 3.4 3 1 1 4 4 3 0 AAA domain AFG1_ATPase PF03969.16 KDO35710.1 - 0.094 11.6 0.0 0.77 8.6 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.6 KDO35710.1 - 0.13 12.0 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KDO35710.1 - 0.21 11.3 0.0 8.1 6.1 0.0 3.1 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KDO35710.1 - 0.23 11.3 0.0 18 5.2 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Arm PF00514.23 KDO35712.1 - 1.2e-33 114.0 16.7 8.4e-10 38.4 0.0 8.9 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KDO35712.1 - 2.1e-18 64.8 11.4 0.013 15.7 0.0 8.2 9 0 0 9 9 8 4 HEAT repeat HEAT_2 PF13646.6 KDO35712.1 - 5.1e-15 55.6 14.9 0.0013 19.1 0.5 5.6 2 2 5 7 7 7 6 HEAT repeats Cnd1 PF12717.7 KDO35712.1 - 2.1e-13 50.6 1.0 0.015 15.3 0.0 4.6 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO35712.1 - 9.1e-12 45.2 21.9 0.00065 20.1 0.4 7.4 6 2 2 8 8 8 6 HEAT-like repeat DNA_alkylation PF08713.11 KDO35712.1 - 9.7e-09 35.2 0.0 0.056 13.2 0.0 4.1 3 1 1 4 4 4 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 KDO35712.1 - 1.2e-07 30.7 4.2 0.0076 14.9 0.1 3.4 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 KDO35712.1 - 9.9e-07 28.6 1.4 0.1 12.1 0.0 3.7 3 1 1 4 4 4 2 CLASP N terminal CHASE6_C PF17150.4 KDO35712.1 - 2.8e-06 27.9 1.5 32 5.3 0.0 6.4 7 0 0 7 7 7 0 C-terminal domain of two-partite extracellular sensor domain V-ATPase_H_N PF03224.14 KDO35712.1 - 3.8e-05 23.1 0.2 0.8 8.9 0.1 3.2 2 1 0 2 2 2 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 KDO35712.1 - 7.6e-05 22.7 1.1 0.5 10.4 0.3 4.3 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.9 KDO35712.1 - 9.8e-05 21.0 2.6 0.0025 16.4 0.1 3.1 2 1 2 4 4 4 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 KDO35712.1 - 0.00027 21.0 0.1 6.1 7.0 0.0 4.3 3 1 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.6 KDO35712.1 - 0.0003 21.0 0.2 1.4 9.2 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_UF PF18817.1 KDO35712.1 - 0.0022 18.2 0.2 1.2 9.4 0.0 4.4 5 0 0 5 5 5 1 Repeat of uncharacterized protein PH0542 Mo25 PF08569.11 KDO35712.1 - 0.012 15.0 0.1 0.98 8.7 0.1 3.0 1 1 1 2 2 2 0 Mo25-like Npa1 PF11707.8 KDO35712.1 - 0.026 13.9 0.3 2.6 7.3 0.0 2.8 3 0 0 3 3 3 0 Ribosome 60S biogenesis N-terminal DUF3144 PF11342.8 KDO35712.1 - 0.11 12.8 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) Arm_2 PF04826.13 KDO35712.1 - 0.11 11.9 2.9 8.1 5.8 0.0 3.6 3 1 2 5 5 5 0 Armadillo-like PPR_long PF17177.4 KDO35713.1 - 3.4e-05 23.3 0.0 0.00013 21.4 0.0 2.0 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KDO35713.1 - 0.0024 18.1 0.1 0.021 15.0 0.0 2.6 3 1 1 4 4 4 1 PPR repeat family PPR PF01535.20 KDO35713.1 - 0.018 15.2 0.1 9.7 6.7 0.0 3.9 4 0 0 4 4 4 0 PPR repeat MNE1 PF13762.6 KDO35713.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Astacin PF01400.24 KDO35714.1 - 8.4e-29 100.6 0.1 1.3e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) YkyA PF10368.9 KDO35715.1 - 5.5e-07 29.4 5.7 5.5e-07 29.4 5.7 3.2 1 1 0 2 2 2 1 Putative cell-wall binding lipoprotein Mce4_CUP1 PF11887.8 KDO35715.1 - 0.0026 17.2 6.5 0.0026 17.2 6.5 2.2 1 1 1 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative Filament PF00038.21 KDO35715.1 - 0.57 9.7 52.0 0.42 10.1 28.3 5.5 3 1 1 5 5 5 0 Intermediate filament protein DUF4407 PF14362.6 KDO35715.1 - 0.75 9.1 56.1 0.59 9.4 5.9 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) PAP_assoc PF03828.19 KDO35716.1 - 8.3e-06 25.9 0.7 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase PAP_central PF04928.17 KDO35716.1 - 0.015 14.3 0.2 0.63 9.0 0.0 2.8 3 0 0 3 3 3 0 Poly(A) polymerase central domain DUF4770 PF15994.5 KDO35716.1 - 2 8.6 9.0 5.3 7.3 9.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Lipoxygenase PF00305.19 KDO35719.1 - 4.9e-14 51.7 2.2 2e-13 49.7 2.2 1.8 1 1 0 1 1 1 1 Lipoxygenase p450 PF00067.22 KDO35719.1 - 2.8e-13 49.4 0.0 7.4e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 EF-hand_6 PF13405.6 KDO35720.1 - 0.017 15.0 0.5 11 6.2 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain WD40 PF00400.32 KDO35721.1 - 4.5e-13 49.5 10.3 0.0011 19.7 0.0 9.1 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KDO35721.1 - 1.4e-08 34.9 0.0 0.5 10.7 0.0 7.2 5 3 3 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain XkdW PF09636.10 KDO35721.1 - 0.064 13.3 0.7 0.45 10.6 0.7 2.6 1 0 0 1 1 1 0 XkdW protein NOA36 PF06524.12 KDO35721.1 - 0.069 12.5 13.2 0.15 11.3 13.2 1.5 1 0 0 1 1 1 0 NOA36 protein Ge1_WD40 PF16529.5 KDO35721.1 - 0.15 11.0 0.2 1.3 7.9 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-B_dimeris PF09026.10 KDO35721.1 - 7.2 7.1 17.4 24 5.4 17.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hydrolase_4 PF12146.8 KDO35722.1 - 1.2e-13 50.9 0.1 9.9e-12 44.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KDO35722.1 - 1.2e-07 31.6 0.1 1.1e-05 25.2 0.2 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KDO35722.1 - 3.4e-06 27.8 0.0 6.6e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KDO35722.1 - 3.4e-05 23.6 0.0 0.0028 17.3 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KDO35722.1 - 9.6e-05 21.2 0.0 0.07 11.8 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 KDO35722.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KDO35722.1 - 0.11 12.0 0.0 0.76 9.2 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 KDO35722.1 - 0.11 12.0 0.0 0.7 9.4 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family PDZ_6 PF17820.1 KDO35723.1 - 1.5e-08 34.4 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KDO35723.1 - 2.4e-07 31.0 0.0 4.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KDO35723.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KDO35723.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Mito_carr PF00153.27 KDO35724.1 - 9.4e-53 176.1 8.7 2.7e-21 75.3 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein bZIP_1 PF00170.21 KDO35725.1 - 2.1e-07 30.9 9.9 3.2e-07 30.3 9.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KDO35725.1 - 9.7e-06 25.6 7.2 1.5e-05 25.0 7.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KDO35725.1 - 0.00034 21.1 1.6 0.00061 20.3 1.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor RGS PF00615.19 KDO35726.1 - 1.1e-24 87.0 4.9 3.2e-15 56.4 0.2 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_60s PF00428.19 KDO35726.1 - 0.016 15.8 0.6 0.052 14.1 0.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein NB-ARC PF00931.22 KDO35726.1 - 0.028 13.6 0.2 0.057 12.6 0.2 1.5 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 KDO35727.1 - 9.4e-62 208.8 0.0 1.3e-60 205.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 KDO35727.1 - 2.3e-53 178.2 0.8 6.6e-17 61.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KDO35727.1 - 4.5e-28 98.2 0.0 6.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO35727.1 - 0.0002 20.8 0.0 0.0033 16.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Cupin_3 PF05899.12 KDO35727.1 - 0.1 12.3 0.0 12 5.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF861) Kdo PF06293.14 KDO35727.1 - 0.13 11.6 0.0 0.74 9.1 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP5K PF01504.18 KDO35728.1 - 2.1e-69 233.8 0.1 3.8e-69 233.0 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 KDO35728.1 - 5.4e-08 32.4 2.2 5.4e-08 32.4 2.2 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KDO35728.1 - 0.044 13.1 7.7 0.11 11.8 7.7 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3180 PF11377.8 KDO35728.1 - 0.86 9.7 7.4 0.15 12.2 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Dicty_CAR PF05462.11 KDO35728.1 - 8.4 5.4 15.0 0.82 8.7 8.2 2.5 2 1 0 2 2 2 0 Slime mold cyclic AMP receptor UMP1 PF05348.11 KDO35729.1 - 8.1e-25 87.4 0.2 8.9e-25 87.2 0.2 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ank_2 PF12796.7 KDO35730.1 - 2.9e-29 101.5 17.7 6.2e-09 36.3 0.4 5.1 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KDO35730.1 - 2.5e-21 75.8 19.5 7.4e-06 26.4 0.5 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KDO35730.1 - 4.5e-12 46.0 23.1 0.38 11.1 0.1 9.3 2 1 8 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KDO35730.1 - 4.7e-11 41.9 12.0 1.4 9.7 0.0 9.1 6 2 3 9 9 9 3 Ankyrin repeat DUF5049 PF16468.5 KDO35730.1 - 2.6e-06 27.2 0.5 0.84 9.6 0.0 5.4 3 1 2 5 5 5 1 Domain of unknown function (DUF5049) Ank PF00023.30 KDO35730.1 - 0.0043 17.4 13.2 0.88 10.1 0.7 7.1 3 2 3 6 6 6 1 Ankyrin repeat Prok-JAB PF14464.6 KDO35730.1 - 3 7.6 8.0 1.7 8.4 2.4 2.8 3 0 0 3 3 3 0 Prokaryotic homologs of the JAB domain PEX11 PF05648.14 KDO35731.1 - 2.5e-13 50.0 0.1 2.9e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Dor1 PF04124.12 KDO35731.1 - 0.016 13.9 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family PH PF00169.29 KDO35732.1 - 0.0012 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 PH domain RAB3GAP2_N PF14655.6 KDO35732.1 - 0.0064 15.8 0.0 0.0082 15.4 0.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus F1F0-ATPsyn_F PF10791.9 KDO35733.1 - 0.031 14.7 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi GAF PF01590.26 KDO35734.1 - 1.1e-14 55.2 0.1 1.1e-10 42.3 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KDO35734.1 - 1.1e-07 32.2 0.1 8.1e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 GAF domain ATG16 PF08614.11 KDO35734.1 - 0.014 15.6 24.2 0.55 10.4 10.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 KDO35734.1 - 0.55 9.1 4.8 0.79 8.6 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cep57_CLD PF14073.6 KDO35734.1 - 1.1 9.2 21.3 4.5 7.3 8.4 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 She9_MDM33 PF05546.11 KDO35734.1 - 1.1 9.0 12.3 0.65 9.8 0.5 2.3 1 1 1 2 2 2 0 She9 / Mdm33 family CorA PF01544.18 KDO35734.1 - 1.9 7.7 12.0 1 8.6 7.4 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 KDO35734.1 - 2.4 8.5 6.4 0.82 10.0 3.3 1.9 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 KDO35734.1 - 3.9 5.3 11.9 29 2.4 11.9 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 KDO35734.1 - 4.7 7.3 24.2 4.9 7.2 11.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KDO35734.1 - 5 7.8 14.0 0.26 11.9 6.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 KDO35734.1 - 5.6 7.1 16.9 0.41 10.7 9.2 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GBP_C PF02841.14 KDO35734.1 - 6.9 6.0 16.3 0.44 9.9 10.6 1.8 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain TMF_TATA_bd PF12325.8 KDO35734.1 - 7.1 6.9 15.0 0.14 12.4 5.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 KDO35734.1 - 9.6 6.0 13.1 0.45 10.3 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pkinase PF00069.25 KDO35735.1 - 5.5e-59 199.7 0.0 7.4e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35735.1 - 1.2e-28 100.1 0.0 1.8e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO35735.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FYVE_2 PF02318.16 KDO35735.1 - 0.031 14.5 9.2 0.074 13.3 9.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Haspin_kinase PF12330.8 KDO35735.1 - 0.059 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Dynein_AAA_lid PF17852.1 KDO35735.1 - 0.08 13.0 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain RRM_2 PF04059.12 KDO35737.1 - 5.6e-45 151.5 0.2 9.1e-45 150.8 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 zf-B_box PF00643.24 KDO35737.1 - 1.4e-06 28.4 18.1 0.00086 19.4 4.4 2.8 2 0 0 2 2 2 2 B-box zinc finger RRM_1 PF00076.22 KDO35737.1 - 1.8e-05 24.5 0.1 0.032 14.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KDO35737.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 KDO35737.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family Kinesin PF00225.23 KDO35738.1 - 3.2e-104 348.5 0.0 3.2e-104 348.5 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KDO35738.1 - 2.2e-44 151.0 0.0 4.3e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding WW PF00397.26 KDO35738.1 - 2e-10 40.6 2.5 3.8e-10 39.7 2.5 1.5 1 0 0 1 1 1 1 WW domain CCDC92 PF14916.6 KDO35738.1 - 0.034 13.9 0.4 0.034 13.9 0.4 2.9 3 0 0 3 3 3 0 Coiled-coil domain of unknown function JIP_LZII PF16471.5 KDO35738.1 - 0.28 11.4 12.7 0.52 10.5 2.7 3.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF641 PF04859.12 KDO35738.1 - 1.8 8.9 28.5 2.4 8.5 5.5 4.3 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) XhlA PF10779.9 KDO35738.1 - 2.5 8.4 7.0 12 6.2 0.1 3.6 2 1 2 4 4 4 0 Haemolysin XhlA DUF1192 PF06698.11 KDO35738.1 - 3.4 7.8 14.3 0.24 11.5 0.5 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Rootletin PF15035.6 KDO35738.1 - 8 6.4 31.4 0.035 14.1 6.3 2.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KDO35738.1 - 9.7 6.2 35.1 1.1 9.3 7.3 4.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcD_C PF12320.8 KDO35739.1 - 0.16 12.3 1.2 2.7 8.4 0.3 2.6 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Nucleoporin_FG2 PF15967.5 KDO35740.1 - 5e-12 45.2 17.1 5e-12 45.2 17.1 4.0 1 1 3 4 4 4 3 Nucleoporin FG repeated region Fmp27_WPPW PF10359.9 KDO35740.1 - 0.0042 16.0 1.2 0.26 10.1 0.0 2.0 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain SlyX PF04102.12 KDO35740.1 - 0.021 15.4 7.6 0.17 12.5 0.8 3.2 3 0 0 3 3 3 0 SlyX IATP PF04568.12 KDO35740.1 - 0.8 10.2 0.0 0.8 10.2 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Nucleoporin_FG PF13634.6 KDO35740.1 - 1.4 9.8 99.8 1.8 9.4 35.9 4.7 2 2 2 4 4 4 0 Nucleoporin FG repeat region Fib_alpha PF08702.10 KDO35740.1 - 5.7 7.1 5.7 3.2 7.9 0.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KDO35740.1 - 8.9 6.1 11.1 5.3 6.8 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MFS_1 PF07690.16 KDO35741.1 - 9e-35 120.2 23.9 9e-35 120.2 23.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KDO35741.1 - 1.3e-23 83.2 11.3 5.6e-13 48.0 0.0 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KDO35741.1 - 1.6e-08 33.9 9.9 1.6e-08 33.9 9.9 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter DUF423 PF04241.15 KDO35743.1 - 6.2e-29 100.1 0.9 6.2e-29 100.1 0.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) CLASP_N PF12348.8 KDO35745.1 - 1.4e-34 119.6 0.4 5.9e-22 78.3 0.1 4.9 4 1 1 5 5 5 2 CLASP N terminal HEAT_2 PF13646.6 KDO35745.1 - 4.5e-09 36.6 3.1 0.7 10.3 0.0 7.1 5 2 1 7 7 7 1 HEAT repeats HEAT PF02985.22 KDO35745.1 - 1.2e-08 34.4 6.3 2.4 8.6 0.0 8.4 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 KDO35745.1 - 2.5e-06 27.7 1.8 2.9 7.9 0.1 5.7 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO35745.1 - 3.3e-05 24.3 5.0 42 4.8 0.0 8.1 8 1 1 9 9 9 0 HEAT-like repeat Adaptin_N PF01602.20 KDO35745.1 - 0.00016 20.4 2.9 0.98 7.9 0.0 4.7 4 2 1 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 KDO35745.1 - 0.00016 21.8 0.1 19 5.5 0.0 5.7 4 3 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DCB PF16213.5 KDO35745.1 - 0.0038 16.9 1.6 0.14 11.8 0.0 3.4 3 1 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 MOR2-PAG1_C PF14225.6 KDO35745.1 - 0.0053 16.6 0.5 12 5.7 0.0 3.9 4 0 0 4 4 4 2 Cell morphogenesis C-terminal Arm PF00514.23 KDO35745.1 - 1.7 8.8 9.2 64 3.8 0.1 6.2 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.8 KDO35745.1 - 5.1 7.7 6.2 26 5.5 0.0 4.7 6 2 1 7 7 5 0 Rix1 complex component involved in 60S ribosome maturation PhoLip_ATPase_C PF16212.5 KDO35746.1 - 5.1e-68 229.5 15.8 5.1e-68 229.5 15.8 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KDO35746.1 - 7.6e-24 83.2 1.4 7.6e-24 83.2 1.4 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KDO35746.1 - 8.6e-12 45.8 0.2 1.9e-05 25.0 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KDO35746.1 - 1.1e-10 41.5 0.0 4.2e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KDO35746.1 - 0.0011 18.5 0.1 0.014 14.9 0.0 2.8 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KDO35746.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-UBR PF02207.20 KDO35747.1 - 1.3e-12 47.7 9.3 1.3e-12 47.7 9.3 3.6 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) TRPM_tetra PF16519.5 KDO35748.1 - 0.001 19.1 3.8 0.11 12.6 0.0 3.6 4 0 0 4 4 4 1 Tetramerisation domain of TRPM Allexi_40kDa PF05549.11 KDO35748.1 - 0.0073 15.8 0.7 0.0073 15.8 0.7 3.7 1 1 3 4 4 4 1 Allexivirus 40kDa protein DUF489 PF04356.12 KDO35748.1 - 0.037 14.1 0.6 0.037 14.1 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF1043 PF06295.12 KDO35748.1 - 0.061 13.3 0.2 0.061 13.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) PI3K_P85_iSH2 PF16454.5 KDO35748.1 - 0.069 12.7 2.8 0.22 11.1 2.8 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tropomyosin_1 PF12718.7 KDO35748.1 - 0.23 11.6 4.6 5.3 7.2 0.7 2.8 1 1 1 2 2 2 0 Tropomyosin like CdvA PF18822.1 KDO35748.1 - 0.29 10.9 3.1 2.1 8.2 0.0 3.9 3 2 3 6 6 6 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 KDO35748.1 - 0.42 10.6 17.6 2.2 8.3 2.1 4.3 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KDO35748.1 - 0.98 9.8 10.6 19 5.7 0.1 4.9 6 0 0 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Polyoma_coat2 PF00761.20 KDO35748.1 - 1.4 8.6 5.8 0.72 9.5 3.1 1.9 2 0 0 2 2 2 0 Polyomavirus coat protein PRKG1_interact PF15898.5 KDO35748.1 - 1.5 9.8 12.3 2.7 8.9 0.6 3.4 3 1 1 4 4 3 0 cGMP-dependent protein kinase interacting domain Sec34 PF04136.15 KDO35748.1 - 1.9 8.3 9.1 2.2 8.1 0.3 3.7 3 1 0 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 KDO35748.1 - 2.9 8.1 14.9 1 9.5 1.1 4.5 3 2 0 5 5 5 0 Fibrinogen alpha/beta chain family DUF148 PF02520.17 KDO35748.1 - 5.3 7.2 7.3 17 5.6 1.8 3.5 3 1 0 3 3 3 0 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.12 KDO35748.1 - 6.7 6.8 24.7 1.6 8.8 0.4 4.6 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein PRELI PF04707.14 KDO35749.1 - 2.9e-34 118.2 0.0 3.3e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Gluconate_2-dh3 PF13618.6 KDO35749.1 - 0.047 13.9 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 HEAT PF02985.22 KDO35750.1 - 1.7e-20 71.3 11.7 0.0013 18.8 0.1 9.2 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 KDO35750.1 - 2.1e-16 60.1 2.0 7.4e-05 23.1 0.0 6.6 3 1 3 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KDO35750.1 - 0.00018 22.0 0.0 0.014 15.9 0.0 3.8 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KDO35750.1 - 0.002 18.2 0.3 8.2 6.4 1.3 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KDO35750.1 - 0.028 14.9 0.7 7.3 7.2 0.0 4.6 3 1 2 5 5 5 0 HEAT-like repeat CLASP_N PF12348.8 KDO35750.1 - 0.041 13.4 0.0 0.57 9.7 0.0 2.4 2 1 0 2 2 2 0 CLASP N terminal SspB PF04386.13 KDO35750.1 - 0.049 13.5 0.7 0.086 12.7 0.7 1.3 1 0 0 1 1 1 0 Stringent starvation protein B AIF-MLS PF14962.6 KDO35750.1 - 7.9 6.4 8.5 19 5.2 8.5 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Pkinase PF00069.25 KDO35751.1 - 7.3e-51 173.1 0.0 1e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35751.1 - 1.4e-48 165.5 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KDO35751.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KDO35751.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KDO35751.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KDO35751.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KDO35751.1 - 0.16 11.9 0.2 0.37 10.7 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.6 KDO35751.1 - 0.3 10.9 4.6 5.5 6.8 0.7 3.2 2 1 1 3 3 3 0 Leucine rich repeat DEAD PF00270.29 KDO35752.1 - 6.8e-47 159.5 0.0 1.4e-46 158.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KDO35752.1 - 2.3e-28 98.8 0.0 8.6e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KDO35752.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF742 PF05331.11 KDO35752.1 - 0.11 12.3 0.2 0.38 10.6 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF742) AAA_22 PF13401.6 KDO35752.1 - 0.27 11.5 0.9 2.8 8.2 0.9 2.4 1 1 0 1 1 1 0 AAA domain Oxidored_FMN PF00724.20 KDO35753.1 - 2.4e-83 280.3 0.0 3.3e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KDO35753.1 - 7e-29 101.0 2.4 1.2e-28 100.3 2.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KDO35753.1 - 1.9e-09 37.6 0.0 1.3e-08 34.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KDO35753.1 - 1.1e-08 34.7 2.1 0.00083 18.7 0.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KDO35753.1 - 2.8e-08 34.2 6.0 0.0009 19.8 1.0 4.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KDO35753.1 - 2.1e-07 30.0 2.8 2.9e-07 29.5 0.5 2.2 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KDO35753.1 - 4.1e-07 29.5 4.2 6.4e-07 28.9 0.1 2.6 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KDO35753.1 - 1.2e-06 28.1 0.3 2e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KDO35753.1 - 7.5e-06 25.3 0.8 1.7e-05 24.1 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KDO35753.1 - 6e-05 22.5 1.7 1 8.7 0.1 3.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KDO35753.1 - 7.8e-05 22.6 1.9 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KDO35753.1 - 0.00012 21.4 0.1 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KDO35753.1 - 0.00027 20.7 0.2 0.00027 20.7 0.2 4.3 4 1 0 5 5 5 1 FAD dependent oxidoreductase GIDA PF01134.22 KDO35753.1 - 0.00062 19.0 0.7 0.00062 19.0 0.7 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KDO35753.1 - 0.0016 18.5 3.7 0.046 13.7 0.1 3.6 4 0 0 4 4 3 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KDO35753.1 - 0.002 17.8 0.5 0.0098 15.5 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KDO35753.1 - 0.003 17.5 0.1 0.04 13.9 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 KDO35753.1 - 0.0051 16.1 0.1 0.0051 16.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 KDO35753.1 - 0.0059 15.1 0.0 0.13 10.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like PglD_N PF17836.1 KDO35753.1 - 0.018 15.7 0.3 6.9 7.4 0.0 3.0 3 0 0 3 3 2 0 PglD N-terminal domain K_oxygenase PF13434.6 KDO35753.1 - 0.046 12.9 0.1 3.9 6.5 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.6 KDO35753.1 - 0.048 14.2 0.5 0.17 12.4 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.17 KDO35753.1 - 0.19 12.3 1.2 17 6.1 0.3 3.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KDO35753.1 - 0.53 10.8 2.9 2 8.9 0.1 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding CoA_binding PF02629.19 KDO35753.1 - 1.2 9.9 3.3 30 5.4 0.0 3.8 4 0 0 4 4 3 0 CoA binding domain Glycoprotein_G PF00802.19 KDO35754.1 - 0.14 11.5 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G eIF3g PF12353.8 KDO35754.1 - 0.95 9.9 5.6 1.2 9.6 0.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G MS_channel PF00924.18 KDO35756.1 - 2.9e-19 69.4 0.0 4.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel UCH PF00443.29 KDO35757.1 - 1.2e-30 106.9 0.0 1.3e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO35757.1 - 8.7e-06 25.5 0.4 4.5e-05 23.2 0.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KDO35757.1 - 0.0001 21.9 0.2 0.003 17.1 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ANXA2R PF15721.5 KDO35757.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Annexin-2 receptor UCH PF00443.29 KDO35758.1 - 3.1e-10 40.0 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KDO35758.1 - 0.00027 20.7 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KDO35758.1 - 0.00029 20.5 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family LRR_9 PF14580.6 KDO35759.1 - 7.7e-15 54.8 11.3 1.5e-14 53.9 0.7 3.2 3 1 1 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 KDO35759.1 - 3e-14 52.9 24.1 2.6e-06 27.7 5.8 4.6 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KDO35759.1 - 6.7e-08 32.2 24.2 2.8e-05 23.8 7.6 3.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KDO35759.1 - 6.5 7.1 12.8 6.2 7.1 0.7 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Cyt-b5 PF00173.28 KDO35760.1 - 2.3e-23 82.1 0.1 5.9e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain PI3_PI4_kinase PF00454.27 KDO35761.1 - 1.1e-36 127.0 0.8 7.3e-34 117.7 0.2 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KDO35761.1 - 0.00013 21.4 0.5 0.00025 20.5 0.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KDO35761.1 - 0.011 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) SnoaL_4 PF13577.6 KDO35762.1 - 7e-11 42.3 0.0 9.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KDO35762.1 - 4.1e-06 27.4 0.1 6.7e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF572 PF04502.13 KDO35763.1 - 3.7e-51 174.7 0.0 4.2e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Cys_rich_KTR PF14205.6 KDO35763.1 - 0.048 13.5 0.0 0.17 11.7 0.0 1.9 1 1 1 2 2 2 0 Cysteine-rich KTR TPR_2 PF07719.17 KDO35764.1 - 2.9e-06 27.0 0.8 0.079 13.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KDO35764.1 - 1.3e-05 24.8 0.3 0.022 14.6 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KDO35764.1 - 0.00026 21.2 0.0 0.00026 21.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KDO35764.1 - 0.079 13.0 0.3 1.2 9.2 0.6 2.7 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain C2 PF00168.30 KDO35764.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 C2 domain PUF PF00806.19 KDO35765.1 - 1.1e-62 204.3 8.4 4.7e-09 35.4 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Pro_CA PF00484.19 KDO35766.1 - 2.5e-99 330.0 3.8 5.2e-49 166.5 0.3 2.1 2 0 0 2 2 2 2 Carbonic anhydrase Membr_traf_MHD PF10540.9 KDO35766.1 - 0.0054 16.9 0.0 4 7.6 0.0 2.2 2 0 0 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF918 PF06033.11 KDO35766.1 - 0.029 14.4 1.2 11 6.1 0.1 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF918) P-mevalo_kinase PF04275.14 KDO35766.1 - 0.032 14.2 0.1 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Phosphomevalonate kinase WI12 PF07107.11 KDO35766.1 - 0.039 14.1 0.5 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Wound-induced protein WI12 zf-IS66 PF13005.7 KDO35766.1 - 0.045 14.2 0.0 9.5 6.7 0.0 2.7 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 AvrPphF-ORF-2 PF09143.10 KDO35766.1 - 0.077 12.9 0.0 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 AvrPphF-ORF-2 PNP_UDP_1 PF01048.20 KDO35766.1 - 0.11 11.7 0.1 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Phosphorylase superfamily RsbRD_N PF14361.6 KDO35766.1 - 0.19 12.4 0.1 32 5.3 0.0 2.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Pro_CA PF00484.19 KDO35767.1 - 3.9e-50 170.2 0.1 5.2e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase NAD_Gly3P_dh_N PF01210.23 KDO35768.1 - 5.5e-39 133.7 0.0 1.1e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KDO35768.1 - 6.5e-38 130.2 0.1 1.1e-37 129.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KDO35768.1 - 1.2e-11 45.0 0.0 3e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KDO35768.1 - 2.6e-08 34.2 0.0 4.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KDO35768.1 - 2.2e-07 30.6 0.0 3.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KDO35768.1 - 4e-07 29.5 0.1 1.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KDO35768.1 - 5.1e-06 26.5 0.0 8.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KDO35768.1 - 0.00049 19.5 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KDO35768.1 - 0.008 17.0 0.2 0.032 15.0 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KDO35768.1 - 0.0085 16.4 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KDO35768.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Pyr_redox_2 PF07992.14 KDO35768.1 - 0.039 13.2 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KDO35768.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KDO35768.1 - 0.077 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KDO35768.1 - 0.12 12.4 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 KDO35768.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Rossmann-like PF10727.9 KDO35768.1 - 0.15 11.9 0.9 0.52 10.2 0.9 1.9 1 1 0 1 1 1 0 Rossmann-like domain LPD7 PF18821.1 KDO35768.1 - 0.22 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 Prenyltransf PF01255.19 KDO35769.1 - 2.4e-70 236.6 0.0 2.8e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3618 PF12277.8 KDO35769.1 - 0.011 16.0 0.2 0.023 14.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF5612 PF18462.1 KDO35769.1 - 0.02 14.7 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) Swi3 PF07962.12 KDO35769.1 - 0.029 14.3 0.0 4.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 ABC2_membrane_3 PF12698.7 KDO35770.1 - 1.9e-52 178.5 61.5 6.8e-34 117.5 29.1 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 KDO35770.1 - 7.7e-52 175.5 0.0 2.6e-27 96.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KDO35770.1 - 7.4e-21 75.2 1.5 4.9e-07 29.8 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KDO35770.1 - 5.7e-05 23.0 0.2 0.16 11.7 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 KDO35770.1 - 0.00024 20.6 0.0 1.1 8.6 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KDO35770.1 - 0.0005 20.6 3.6 0.0029 18.1 0.2 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane PF01061.24 KDO35770.1 - 0.00059 19.3 51.1 0.0036 16.7 20.2 3.8 4 0 0 4 4 4 2 ABC-2 type transporter SbcCD_C PF13558.6 KDO35770.1 - 0.0016 18.6 0.0 0.82 10.0 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KDO35770.1 - 0.0029 17.3 1.4 0.011 15.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KDO35770.1 - 0.0034 17.3 0.2 0.037 13.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KDO35770.1 - 0.018 14.8 0.2 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KDO35770.1 - 0.02 15.3 0.0 4.7 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 KDO35770.1 - 0.022 14.6 1.8 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 MukB N-terminal MMR_HSR1 PF01926.23 KDO35770.1 - 0.15 12.1 0.2 7.1 6.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4162 PF13732.6 KDO35770.1 - 0.17 12.6 0.2 18 6.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) SRP54 PF00448.22 KDO35770.1 - 0.29 10.7 3.3 8.9 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 KDO35771.1 - 3.3e-41 140.8 0.0 5.4e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KDO35771.1 - 2e-10 40.5 0.1 5e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KDO35771.1 - 5.9e-07 30.0 0.0 0.00053 20.4 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KDO35771.1 - 1.4e-05 25.1 0.1 0.00013 22.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KDO35771.1 - 1.9e-05 24.9 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KDO35771.1 - 4.8e-05 23.7 0.4 0.035 14.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KDO35771.1 - 7.5e-05 22.5 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KDO35771.1 - 0.0019 17.9 0.1 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 KDO35771.1 - 0.0023 17.1 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KDO35771.1 - 0.0024 18.2 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Prot_ATP_OB_N PF17758.1 KDO35771.1 - 0.0025 17.4 0.3 0.0095 15.6 0.0 2.0 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KDO35771.1 - 0.004 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KDO35771.1 - 0.0061 17.1 0.0 0.015 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KDO35771.1 - 0.008 15.4 0.4 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 KDO35771.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KDO35771.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KDO35771.1 - 0.017 14.7 0.2 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KDO35771.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KDO35771.1 - 0.024 14.0 0.1 0.11 11.8 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 KDO35771.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KDO35771.1 - 0.027 14.2 0.0 0.087 12.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KDO35771.1 - 0.028 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KDO35771.1 - 0.042 13.3 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KDO35771.1 - 0.053 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KDO35771.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KDO35771.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KDO35771.1 - 0.093 12.6 0.2 0.36 10.7 0.0 2.1 2 1 1 3 3 2 0 NACHT domain Herpes_pp85 PF04637.12 KDO35771.1 - 5.9 5.2 5.8 9.2 4.6 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pro_isomerase PF00160.21 KDO35773.1 - 3.2e-37 128.2 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VPS13_C PF16909.5 KDO35774.1 - 5.3e-40 137.1 2.1 1.8e-35 122.3 0.1 2.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KDO35774.1 - 2.4e-20 72.8 0.1 7.3e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 C2 PF00168.30 KDO35774.1 - 1.3e-10 41.5 0.0 2.2e-08 34.3 0.0 3.0 2 0 0 2 2 2 1 C2 domain VPS13 PF16908.5 KDO35774.1 - 3.3e-07 30.4 1.1 4.7e-05 23.3 1.1 2.8 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 KDO35774.1 - 0.00032 20.2 0.0 0.44 9.9 0.0 3.1 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 KDO35774.1 - 0.015 15.7 0.0 0.052 13.9 0.0 1.9 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain DIOX_N PF14226.6 KDO35775.1 - 2.5e-28 99.2 0.0 3.6e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KDO35775.1 - 8.1e-23 80.8 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBM_1 PF00734.18 KDO35776.1 - 5.5e-16 58.2 35.9 7.6e-09 35.4 10.9 7.1 6 1 0 6 6 6 3 Fungal cellulose binding domain CarbpepA_inh PF02977.15 KDO35776.1 - 0.039 13.7 0.9 0.039 13.7 0.9 3.7 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor HA2 PF04408.23 KDO35777.1 - 7.6e-23 80.9 1.2 2.5e-22 79.2 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KDO35777.1 - 4.2e-13 49.4 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KDO35777.1 - 2.4e-09 37.5 0.0 5.9e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KDO35777.1 - 1e-06 28.7 0.1 2.8e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KDO35777.1 - 1.8e-05 25.0 0.1 8.1e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KDO35777.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KDO35777.1 - 0.0025 18.2 0.1 0.0069 16.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KDO35777.1 - 0.0053 16.9 0.5 0.059 13.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.14 KDO35777.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 KDO35777.1 - 0.0064 15.8 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KDO35777.1 - 0.012 15.7 0.5 7.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KDO35777.1 - 0.015 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KDO35777.1 - 0.026 14.5 0.1 0.14 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KDO35777.1 - 0.034 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KDO35777.1 - 0.038 14.5 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KDO35777.1 - 0.041 14.4 0.3 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KDO35777.1 - 0.041 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KDO35777.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 KDO35777.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 KDO35777.1 - 0.12 12.5 0.1 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KDO35778.1 - 4.8e-54 183.5 0.0 1.2e-53 182.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KDO35778.1 - 6.1e-34 117.5 0.0 1.2e-32 113.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KDO35778.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KDO35778.1 - 0.014 15.3 0.1 0.064 13.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KDO35778.1 - 0.065 12.8 0.5 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KDO35778.1 - 0.089 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KDO35778.1 - 0.12 11.8 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YjgF_endoribonc PF14588.6 KDO35779.1 - 8.4e-30 103.9 0.0 9.6e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 KDO35779.1 - 2.7e-17 62.9 0.0 3.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP His_Phos_2 PF00328.22 KDO35780.1 - 6.8e-14 52.0 2.0 9.9e-06 25.1 1.6 3.0 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Myosin_head PF00063.21 KDO35781.1 - 7e-24 84.0 0.1 8.2e-24 83.8 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KDO35781.1 - 2.9e-08 33.4 0.1 1.1e-07 31.6 0.1 1.8 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.21 KDO35782.1 - 1.3e-173 578.9 0.1 2.2e-173 578.1 0.1 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KDO35782.1 - 8.4e-10 37.6 22.6 0.0038 16.9 1.3 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif DivIC PF04977.15 KDO35782.1 - 0.0017 18.1 12.4 0.047 13.5 0.4 3.9 4 0 0 4 4 4 2 Septum formation initiator TraC PF07820.12 KDO35782.1 - 0.19 12.1 10.4 1.6 9.1 1.5 4.3 4 0 0 4 4 4 0 TraC-like protein PriA_C PF18074.1 KDO35782.1 - 0.49 11.2 2.2 4.3 8.2 0.1 3.6 3 0 0 3 3 3 0 Primosomal protein N C-terminal domain TLE_N PF03920.15 KDO35782.1 - 4.4 7.4 9.6 9.5 6.3 0.3 2.8 1 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DegT_DnrJ_EryC1 PF01041.17 KDO35783.1 - 1e-30 107.3 0.0 4.9e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KDO35783.1 - 0.017 14.1 0.0 0.061 12.3 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KDO35783.1 - 0.025 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II zf-RVT PF13966.6 KDO35784.1 - 0.0015 19.2 0.7 0.0015 19.2 0.7 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Pro_CA PF00484.19 KDO35785.1 - 1.1e-13 51.8 0.0 1.3e-13 51.6 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Saprolegnia_parasitica_CBS_223.65-ASM15154v2/GCA_000151545.2_ASM15154v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Saprolegnia_parasitica_CBS_223.65-ASM15154v2/GCA_000151545.2_ASM15154v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Saprolegnia_parasitica_CBS_223.65-ASM15154v2/GCA_000151545.2_ASM15154v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Saprolegnia_parasitica_CBS_223.65-ASM15154v2/GCA_000151545.2_ASM15154v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 12:09:54 2019 # [ok]